locus-tag	class	description
CWI64_RS00065	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CWI64_RS00070	COG1438	arginine binding
CWI64_RS00090	COG0469	pyruvate kinase activity
CWI64_RS00140	COG3689	TIGRFAM TIGR03943 family protein
CWI64_RS00145	COG0701	Predicted permease
CWI64_RS00160	COG2183	response to ionizing radiation
CWI64_RS00180	COG1136	(ABC) transporter
CWI64_RS00185	COG0577	efflux transmembrane transporter activity
CWI64_RS00205	COG1982	Orn Lys Arg decarboxylase major
CWI64_RS00215	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CWI64_RS00235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CWI64_RS00240	COG0561	phosphatase activity
CWI64_RS00260	COG0583	DNA-binding transcription factor activity
CWI64_RS00265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CWI64_RS00270	COG0564	pseudouridine synthase activity
CWI64_RS00275	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
CWI64_RS00290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CWI64_RS00300	COG0470	DNA polymerase III
CWI64_RS00340	COG0528	UMP kinase activity
CWI64_RS00350	COG2996	Protein conserved in bacteria
CWI64_RS00360	COG1702	phosphate starvation-inducible protein PhoH
CWI64_RS00395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWI64_RS00400	COG1596	polysaccharide export
CWI64_RS00400	COG1555	photosystem II stabilization
CWI64_RS00405	COG0658	competence protein
CWI64_RS00405	COG2333	competence protein COMEC
CWI64_RS00415	COG1131	(ABC) transporter
CWI64_RS00445	COG0543	2 iron, 2 sulfur cluster binding
CWI64_RS00450	COG0167	dihydroorotate dehydrogenase activity
CWI64_RS00455	COG4193	domain, Protein
CWI64_RS00455	COG5263	repeat protein
CWI64_RS00460	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CWI64_RS00470	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CWI64_RS00480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CWI64_RS00485	COG0237	dephospho-CoA kinase activity
CWI64_RS00490	COG2814	Major facilitator Superfamily
CWI64_RS00495	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI64_RS00505	COG0557	exoribonuclease II activity
CWI64_RS00515	COG3615	Tellurite resistance protein tehB
CWI64_RS00515	COG0500	methyltransferase
CWI64_RS00530	COG4122	O-methyltransferase activity
CWI64_RS00560	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CWI64_RS00580	COG0494	nUDIX hydrolase
CWI64_RS00590	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CWI64_RS00600	COG2176	DNA-directed DNA polymerase activity
CWI64_RS00605	COG0584	glycerophosphoryl diester phosphodiesterase
CWI64_RS00625	COG0785	Cytochrome C biogenesis protein
CWI64_RS00630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWI64_RS00635	COG0531	amino acid
CWI64_RS00640	COG3443	Belongs to the bacterial solute-binding protein 9 family
CWI64_RS00640	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWI64_RS00690	COG1970	mechanosensitive ion channel activity
CWI64_RS00700	COG4708	membrane
CWI64_RS00715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CWI64_RS00725	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CWI64_RS00730	COG1942	4-Oxalocrotonate Tautomerase
CWI64_RS00735	COG1435	thymidine kinase activity
CWI64_RS00745	COG2890	protein-(glutamine-N5) methyltransferase activity
CWI64_RS00770	COG0741	lytic transglycosylase activity
CWI64_RS00780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWI64_RS00805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI64_RS00810	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI64_RS00855	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CWI64_RS00880	COG1597	lipid kinase activity
CWI64_RS00895	COG1396	sequence-specific DNA binding
CWI64_RS00900	COG0542	response to heat
CWI64_RS00910	COG1196	nuclear chromosome segregation
CWI64_RS00925	COG3843	relaxase mobilization nuclease domain protein
CWI64_RS00990	COG1396	sequence-specific DNA binding
CWI64_RS01015	COG0772	Belongs to the SEDS family
CWI64_RS01020	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CWI64_RS01045	COG0358	DNA primase activity
CWI64_RS01050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CWI64_RS01055	COG2151	metal-sulfur cluster biosynthetic enzyme
CWI64_RS01060	COG0438	transferase activity, transferring glycosyl groups
CWI64_RS01065	COG0438	transferase activity, transferring glycosyl groups
CWI64_RS01095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWI64_RS01105	COG4109	DRTGG domain
CWI64_RS01110	COG0024	Methionine aminopeptidase
CWI64_RS01125	COG0210	DNA helicase
CWI64_RS01135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWI64_RS01155	COG1104	cysteine desulfurase activity
CWI64_RS01160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWI64_RS01170	COG2357	RelA SpoT domain protein
CWI64_RS01180	COG0564	pseudouridine synthase activity
CWI64_RS01185	COG0280	phosphate acetyltransferase
CWI64_RS01225	COG0196	riboflavin kinase activity
CWI64_RS01230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWI64_RS01235	COG1307	EDD domain protein, DegV family
CWI64_RS01245	COG0488	(ABC) transporter
CWI64_RS01265	COG1523	belongs to the glycosyl hydrolase 13 family
CWI64_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
CWI64_RS01280	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CWI64_RS01290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CWI64_RS01365	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWI64_RS01385	COG0095	Lipoate-protein ligase
CWI64_RS01390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI64_RS01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
CWI64_RS01400	COG0022	dehydrogenase e1 component
CWI64_RS01405	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CWI64_RS01410	COG0534	Mate efflux family protein
CWI64_RS01420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CWI64_RS01425	COG1051	belongs to the nudix hydrolase family
CWI64_RS01440	COG1011	Hydrolase
CWI64_RS01445	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
CWI64_RS01465	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS01470	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CWI64_RS01475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI64_RS01480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CWI64_RS01520	COG3711	transcriptional antiterminator
CWI64_RS01525	COG3684	Belongs to the aldolase LacD family
CWI64_RS01575	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CWI64_RS01580	COG0497	DNA recombination
CWI64_RS01585	COG1438	arginine binding
CWI64_RS01590	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CWI64_RS01625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CWI64_RS01645	COG3764	Sortase (surface protein transpeptidase)
CWI64_RS01650	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWI64_RS01675	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CWI64_RS01680	COG5002	protein histidine kinase activity
CWI64_RS01685	COG0745	RESPONSE REGULATOR receiver
CWI64_RS01690	COG1194	a g-specific adenine glycosylase
CWI64_RS01705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CWI64_RS01710	COG4684	Psort location CytoplasmicMembrane, score
CWI64_RS01720	COG1827	regulation of RNA biosynthetic process
CWI64_RS01750	COG0765	amino acid transport
CWI64_RS01755	COG1126	abc transporter atp-binding protein
CWI64_RS01760	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CWI64_RS01765	COG0552	protein localization to endoplasmic reticulum
CWI64_RS01770	COG0561	phosphatase activity
CWI64_RS01775	COG0561	phosphatase activity
CWI64_RS01780	COG1196	nuclear chromosome segregation
CWI64_RS01805	COG1401	restriction endodeoxyribonuclease activity
CWI64_RS01820	COG0066	3-isopropylmalate dehydratase activity
CWI64_RS01830	COG0473	3-isopropylmalate dehydrogenase activity
CWI64_RS01850	COG3142	Participates in the control of copper homeostasis
CWI64_RS01855	COG2832	Protein of unknown function (DUF454)
CWI64_RS01860	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CWI64_RS01875	COG0758	DNA mediated transformation
CWI64_RS01880	COG4750	Nucleotidyl transferase
CWI64_RS01895	COG1063	alcohol dehydrogenase
CWI64_RS01910	COG3475	LICD family
CWI64_RS01915	COG3475	LICD family
CWI64_RS01925	COG0505	Belongs to the CarA family
CWI64_RS01940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CWI64_RS01955	COG0488	(ABC) transporter
CWI64_RS01965	COG1704	LemA family
CWI64_RS01980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CWI64_RS01995	COG1078	dGTPase activity
CWI64_RS02020	COG1396	sequence-specific DNA binding
CWI64_RS02035	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWI64_RS02040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CWI64_RS02045	COG1605	Chorismate mutase
CWI64_RS02045	COG0077	Prephenate dehydratase
CWI64_RS02050	COG0716	FMN binding
CWI64_RS02055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWI64_RS02075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CWI64_RS02130	COG2081	HI0933 family
CWI64_RS02145	COG0395	ABC-type sugar transport system, permease component
CWI64_RS02150	COG4209	transmembrane transport
CWI64_RS02155	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CWI64_RS02185	COG0577	efflux transmembrane transporter activity
CWI64_RS02185	COG1136	(ABC) transporter
CWI64_RS02195	COG0515	serine threonine protein kinase
CWI64_RS02245	COG0402	S-adenosylhomocysteine deaminase activity
CWI64_RS02260	COG1132	(ABC) transporter
CWI64_RS02265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI64_RS02265	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI64_RS02300	COG1215	transferase activity, transferring glycosyl groups
CWI64_RS02310	COG3475	LICD family
CWI64_RS02320	COG0077	Prephenate dehydratase
CWI64_RS02325	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CWI64_RS02340	COG0287	Prephenate dehydrogenase
CWI64_RS02365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CWI64_RS02415	COG1177	transmembrane transport
CWI64_RS02420	COG3842	ATPase activity
CWI64_RS02435	COG3527	Alpha-acetolactate decarboxylase
CWI64_RS02445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CWI64_RS02450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS02455	COG0704	Plays a role in the regulation of phosphate uptake
CWI64_RS02460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWI64_RS02465	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWI64_RS02470	COG0581	inorganic phosphate transmembrane transporter activity
CWI64_RS02475	COG0573	inorganic phosphate transmembrane transporter activity
CWI64_RS02480	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWI64_RS02485	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWI64_RS02485	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CWI64_RS02490	COG0483	inositol monophosphate 1-phosphatase activity
CWI64_RS02500	COG1393	Belongs to the ArsC family
CWI64_RS02510	COG0647	UMP catabolic process
CWI64_RS02520	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CWI64_RS02565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CWI64_RS02575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CWI64_RS02645	COG2188	Transcriptional regulator
CWI64_RS02650	COG0697	spore germination
CWI64_RS02655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CWI64_RS02670	COG0561	phosphatase activity
CWI64_RS02705	COG0492	ferredoxin-NADP+ reductase activity
CWI64_RS02715	COG1126	abc transporter atp-binding protein
CWI64_RS02725	COG1393	Belongs to the ArsC family
CWI64_RS02730	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CWI64_RS02745	COG1272	protein, Hemolysin III
CWI64_RS02760	COG1136	(ABC) transporter
CWI64_RS02760	COG0577	efflux transmembrane transporter activity
CWI64_RS02790	COG0431	NADPH-dependent FMN reductase
CWI64_RS02790	COG1053	succinate dehydrogenase
CWI64_RS02790	COG3976	FMN-binding domain protein
CWI64_RS02820	COG0656	L-ascorbic acid biosynthetic process
CWI64_RS02825	COG0726	polysaccharide deacetylase
CWI64_RS02855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWI64_RS02890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CWI64_RS02905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS02910	COG1126	abc transporter atp-binding protein
CWI64_RS02925	COG0628	permease
CWI64_RS02930	COG2706	6-phosphogluconolactonase activity
CWI64_RS02995	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CWI64_RS03020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWI64_RS03025	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CWI64_RS03030	COG0626	cystathionine gamma-synthase activity
CWI64_RS03035	COG1132	(ABC) transporter
CWI64_RS03045	COG1132	(ABC) transporter
CWI64_RS03050	COG4166	transmembrane transport
CWI64_RS03055	COG2244	polysaccharide biosynthetic process
CWI64_RS03060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CWI64_RS03085	COG2827	Endonuclease containing a URI domain
CWI64_RS03090	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CWI64_RS03095	COG1098	S1 RNA binding domain
CWI64_RS03105	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CWI64_RS03110	COG0629	single-stranded DNA binding
CWI64_RS03120	COG0017	Asparaginyl-tRNA synthetase
CWI64_RS03130	COG0436	Aminotransferase
CWI64_RS03170	COG0242	peptide deformylase activity
CWI64_RS03175	COG0625	glutathione transferase activity
CWI64_RS03185	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CWI64_RS03190	COG0488	(ABC) transporter
CWI64_RS03195	COG0617	tRNA 3'-terminal CCA addition
CWI64_RS03205	COG1307	EDD domain protein, DegV family
CWI64_RS03225	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CWI64_RS03240	COG1481	regulation of sporulation
CWI64_RS03245	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CWI64_RS03255	COG0251	oxidation-reduction process
CWI64_RS03275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CWI64_RS03295	COG3935	DnaD domain protein
CWI64_RS03310	COG2226	methyltransferase
CWI64_RS03315	COG3842	ATPase activity
CWI64_RS03325	COG1335	isochorismatase
CWI64_RS03340	COG0513	Belongs to the DEAD box helicase family
CWI64_RS03345	COG2223	nitrite transmembrane transporter activity
CWI64_RS03350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI64_RS03355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWI64_RS03360	COG3442	glutamine amidotransferase
CWI64_RS03365	COG0006	proline dipeptidase activity
CWI64_RS03380	COG4720	Psort location CytoplasmicMembrane, score
CWI64_RS03385	COG0351	phosphomethylpyrimidine kinase
CWI64_RS03410	COG2824	Alkylphosphonate utilization operon protein PhnA
CWI64_RS03415	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CWI64_RS03440	COG0463	Glycosyl transferase, family 2
CWI64_RS03445	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWI64_RS03450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CWI64_RS03455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CWI64_RS03460	COG2384	SAM-dependent methyltransferase
CWI64_RS03480	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CWI64_RS03485	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CWI64_RS03490	COG0204	Acyl-transferase
CWI64_RS03505	COG2910	NAD(P)H-binding
CWI64_RS03530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CWI64_RS03535	COG5002	protein histidine kinase activity
CWI64_RS03540	COG0745	RESPONSE REGULATOR receiver
CWI64_RS03555	COG1959	2 iron, 2 sulfur cluster binding
CWI64_RS03610	COG3590	peptidase
CWI64_RS03625	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWI64_RS03630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CWI64_RS03640	COG1136	(ABC) transporter
CWI64_RS03640	COG0577	efflux transmembrane transporter activity
CWI64_RS03680	COG3599	regulation of cell shape
CWI64_RS03700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CWI64_RS03720	COG1051	belongs to the nudix hydrolase family
CWI64_RS03725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CWI64_RS03740	COG0768	penicillin binding
CWI64_RS03755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CWI64_RS03775	COG2731	YhcH YjgK YiaL family protein
CWI64_RS03785	COG0395	ABC-type sugar transport system, permease component
CWI64_RS03790	COG1175	transmembrane transport
CWI64_RS03800	COG2190	(PTS) system
CWI64_RS03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS03800	COG1263	PTS System
CWI64_RS03810	COG0673	inositol 2-dehydrogenase activity
CWI64_RS03815	COG4409	exo-alpha-(2->6)-sialidase activity
CWI64_RS03825	COG1175	transmembrane transport
CWI64_RS03830	COG1653	transport
CWI64_RS03855	COG3458	cephalosporin-C deacetylase activity
CWI64_RS03865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CWI64_RS03880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWI64_RS03885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CWI64_RS03890	COG0653	protein targeting
CWI64_RS03900	COG1131	(ABC) transporter
CWI64_RS03930	COG0778	Nitroreductase
CWI64_RS03935	COG1484	DNA-dependent DNA replication
CWI64_RS03950	COG1725	Transcriptional regulator
CWI64_RS03955	COG1131	(ABC) transporter
CWI64_RS03965	COG1668	transmembrane transport
CWI64_RS03970	COG4152	abc transporter atp-binding protein
CWI64_RS03990	COG1940	carbohydrate kinase activity
CWI64_RS03995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS03995	COG2190	(PTS) system
CWI64_RS03995	COG1263	PTS System
CWI64_RS04005	COG1621	beta-fructofuranosidase activity
CWI64_RS04010	COG1609	Transcriptional regulator
CWI64_RS04020	COG3425	synthase
CWI64_RS04045	COG0515	serine threonine protein kinase
CWI64_RS04045	COG2815	serine threonine protein kinase
CWI64_RS04050	COG0631	protein serine/threonine phosphatase activity
CWI64_RS04055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CWI64_RS04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CWI64_RS04065	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CWI64_RS04075	COG0194	GDP metabolic process
CWI64_RS04090	COG4115	mRNA cleavage
CWI64_RS04105	COG2226	methyltransferase
CWI64_RS04110	COG0799	negative regulation of ribosome biogenesis
CWI64_RS04120	COG1713	HD superfamily hydrolase involved in NAD metabolism
CWI64_RS04125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CWI64_RS04130	COG1534	Rna-binding protein
CWI64_RS04135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CWI64_RS04150	COG0668	transmembrane transport
CWI64_RS04180	COG3118	belongs to the thioredoxin family
CWI64_RS04185	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CWI64_RS04195	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWI64_RS04205	COG1164	Oligoendopeptidase f
CWI64_RS04210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CWI64_RS04280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CWI64_RS04290	COG1621	beta-fructofuranosidase activity
CWI64_RS04295	COG1653	transport
CWI64_RS04300	COG0395	ABC-type sugar transport system, permease component
CWI64_RS04305	COG4209	transmembrane transport
CWI64_RS04315	COG3711	transcriptional antiterminator
CWI64_RS04320	COG2261	transglycosylase associated protein
CWI64_RS04340	COG3237	CsbD-like
CWI64_RS04355	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CWI64_RS04365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS04370	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWI64_RS04375	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS04385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS04390	COG1846	Transcriptional regulator
CWI64_RS04390	COG1940	carbohydrate kinase activity
CWI64_RS04400	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CWI64_RS04445	COG0512	Glutamine amidotransferase of anthranilate synthase
CWI64_RS04450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWI64_RS04470	COG1285	pathogenesis
CWI64_RS04475	COG1178	ABC-type Fe3 transport system permease component
CWI64_RS04495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CWI64_RS04500	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWI64_RS04505	COG0704	Plays a role in the regulation of phosphate uptake
CWI64_RS04520	COG5434	Belongs to the glycosyl hydrolase 28 family
CWI64_RS04530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CWI64_RS04535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CWI64_RS04545	COG1132	(ABC) transporter
CWI64_RS04550	COG1132	(ABC) transporter
CWI64_RS04570	COG0708	Exodeoxyribonuclease III
CWI64_RS04590	COG2233	PERMEase
CWI64_RS04615	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CWI64_RS04620	COG1609	Transcriptional regulator
CWI64_RS04625	COG1063	alcohol dehydrogenase
CWI64_RS04630	COG0789	Transcriptional regulator
CWI64_RS04635	COG1230	cation diffusion facilitator family transporter
CWI64_RS04645	COG3201	nicotinamide mononucleotide transporter
CWI64_RS04650	COG1732	Glycine betaine
CWI64_RS04675	COG1363	Peptidase, m42
CWI64_RS04695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CWI64_RS04700	COG4605	iron ion homeostasis
CWI64_RS04705	COG4604	ABC transporter, ATP-binding protein
CWI64_RS04710	COG4607	ABC-type enterochelin transport system periplasmic component
CWI64_RS04720	COG1187	pseudouridine synthase activity
CWI64_RS04740	COG0517	IMP dehydrogenase activity
CWI64_RS04750	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CWI64_RS04765	COG0366	Alpha amylase catalytic
CWI64_RS04775	COG1263	PTS System
CWI64_RS04775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS04780	COG2188	Transcriptional regulator
CWI64_RS04785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWI64_RS04800	COG4608	Belongs to the ABC transporter superfamily
CWI64_RS04805	COG0444	Belongs to the ABC transporter superfamily
CWI64_RS04810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CWI64_RS04815	COG0601	transmembrane transport
CWI64_RS04820	COG4166	transmembrane transport
CWI64_RS04840	COG0366	Alpha amylase catalytic
CWI64_RS04845	COG0395	ABC-type sugar transport system, permease component
CWI64_RS04850	COG1175	transmembrane transport
CWI64_RS04855	COG1653	transport
CWI64_RS04860	COG3345	alpha-galactosidase
CWI64_RS04865	COG2207	Transcriptional regulator
CWI64_RS04870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CWI64_RS04870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CWI64_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CWI64_RS05005	COG2137	regulation of response to DNA damage stimulus
CWI64_RS05035	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CWI64_RS05045	COG4221	oxidoreductase activity
CWI64_RS05050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI64_RS05055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWI64_RS05100	COG1012	belongs to the aldehyde dehydrogenase family
CWI64_RS05220	COG5263	repeat protein
CWI64_RS05220	COG5632	N-Acetylmuramoyl-L-alanine amidase
CWI64_RS05245	COG1316	TRANSCRIPTIONal
CWI64_RS05255	COG0802	atpase or kinase
CWI64_RS05320	COG0577	efflux transmembrane transporter activity
CWI64_RS05320	COG1136	(ABC) transporter
CWI64_RS05355	COG1253	flavin adenine dinucleotide binding
CWI64_RS05370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CWI64_RS05380	COG3480	Lon protease (S16) C-terminal proteolytic domain
CWI64_RS05390	COG0742	ribosomal rna small subunit methyltransferase
CWI64_RS05410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CWI64_RS05415	COG1254	Belongs to the acylphosphatase family
CWI64_RS05425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWI64_RS05435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CWI64_RS05455	COG1564	THIamine pyrophosphokinase
CWI64_RS05465	COG1162	GTPase activity
CWI64_RS05470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CWI64_RS05495	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CWI64_RS05500	COG0084	hydrolase, TatD family'
CWI64_RS05520	COG0436	Aminotransferase
CWI64_RS05530	COG0589	response to stress
CWI64_RS05535	COG0561	phosphatase activity
CWI64_RS05540	COG0252	asparaginase activity
CWI64_RS05545	COG1609	Transcriptional regulator
CWI64_RS05550	COG2197	response regulator
CWI64_RS05555	COG4585	Histidine kinase
CWI64_RS05560	COG0842	Transport permease protein
CWI64_RS05565	COG1131	(ABC) transporter
CWI64_RS05665	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI64_RS05670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI64_RS05690	COG0577	efflux transmembrane transporter activity
CWI64_RS05700	COG0157	Belongs to the NadC ModD family
CWI64_RS05720	COG1129	ABC transporter
CWI64_RS05730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS05740	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWI64_RS05745	COG1454	alcohol dehydrogenase
CWI64_RS05745	COG1012	belongs to the aldehyde dehydrogenase family
CWI64_RS05755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CWI64_RS05765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CWI64_RS05785	COG3623	hexulose-6-phosphate isomerase
CWI64_RS05795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS05805	COG3037	sugar-specific permease SgaT UlaA
CWI64_RS05815	COG1847	R3H domain protein
CWI64_RS05820	COG0706	membrane insertase activity
CWI64_RS05865	COG4537	Required for transformation and DNA binding
CWI64_RS05870	COG1459	type II secretion system
CWI64_RS05875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CWI64_RS05885	COG1063	alcohol dehydrogenase
CWI64_RS05915	COG3759	membrane
CWI64_RS05930	COG0131	Imidazoleglycerol-phosphate dehydratase
CWI64_RS05930	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CWI64_RS05935	COG0534	Mate efflux family protein
CWI64_RS06050	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CWI64_RS06055	COG1132	(ABC) transporter
CWI64_RS06065	COG1132	(ABC) transporter
CWI64_RS06075	COG1438	arginine binding
CWI64_RS06095	COG0745	RESPONSE REGULATOR receiver
CWI64_RS06100	COG5002	protein histidine kinase activity
CWI64_RS06105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CWI64_RS06110	COG0573	inorganic phosphate transmembrane transporter activity
CWI64_RS06120	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CWI64_RS06125	COG0704	Plays a role in the regulation of phosphate uptake
CWI64_RS06145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CWI64_RS06155	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CWI64_RS06170	COG0697	spore germination
CWI64_RS06175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI64_RS06175	COG4499	WXG100 protein secretion system (Wss), protein YukC
CWI64_RS06185	COG2217	Heavy metal translocating P-type atpase
CWI64_RS06195	COG2226	methyltransferase
CWI64_RS06215	COG0058	SHG alpha-glucan phosphorylase activity
CWI64_RS06220	COG1640	4-alpha-glucanotransferase
CWI64_RS06225	COG2182	Extracellular solute-binding protein
CWI64_RS06230	COG1175	transmembrane transport
CWI64_RS06235	COG3833	ABC-type maltose transport systems, permease component
CWI64_RS06245	COG5521	maltodextrose utilization protein MalA
CWI64_RS06250	COG1609	Transcriptional regulator
CWI64_RS06260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CWI64_RS06295	COG1476	TRANSCRIPTIONal
CWI64_RS06330	COG2151	metal-sulfur cluster biosynthetic enzyme
CWI64_RS06340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CWI64_RS06345	COG3959	Transketolase, thiamine diphosphate binding domain
CWI64_RS06360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS06380	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CWI64_RS06415	COG0383	alpha-mannosidase activity
CWI64_RS06425	COG3537	Alpha-1,2-mannosidase
CWI64_RS06450	COG0549	Belongs to the carbamate kinase family
CWI64_RS06455	COG1288	antiporter activity
CWI64_RS06460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWI64_RS06470	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CWI64_RS06470	COG3583	domain protein
CWI64_RS06470	COG3064	Membrane
CWI64_RS06485	COG1454	alcohol dehydrogenase
CWI64_RS06505	COG3716	PTS system mannose fructose sorbose family IID component
CWI64_RS06515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS06535	COG1070	Carbohydrate kinase
CWI64_RS06550	COG3443	Belongs to the bacterial solute-binding protein 9 family
CWI64_RS06550	COG0803	Belongs to the bacterial solute-binding protein 9 family
CWI64_RS06555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CWI64_RS06560	COG1121	(ABC) transporter
CWI64_RS06565	COG1846	Transcriptional regulator
CWI64_RS06570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CWI64_RS06580	COG1696	Membrane protein involved in D-alanine export
CWI64_RS06595	COG2211	Major facilitator Superfamily
CWI64_RS06625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CWI64_RS06630	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CWI64_RS06650	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CWI64_RS06670	COG1755	Isoprenylcysteine carboxyl methyltransferase
CWI64_RS06675	COG5002	protein histidine kinase activity
CWI64_RS06680	COG0745	RESPONSE REGULATOR receiver
CWI64_RS06695	COG0542	response to heat
CWI64_RS06700	COG4463	regulation of RNA biosynthetic process
CWI64_RS06705	COG1116	anion transmembrane transporter activity
CWI64_RS06710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CWI64_RS06715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CWI64_RS06735	COG0305	Participates in initiation and elongation during chromosome replication
CWI64_RS06755	COG1040	competence protein
CWI64_RS06760	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CWI64_RS06765	COG1739	Uncharacterized protein family UPF0029
CWI64_RS06800	COG0052	Belongs to the universal ribosomal protein uS2 family
CWI64_RS06805	COG3942	CHAP domain
CWI64_RS06815	COG1792	Involved in formation and maintenance of cell shape
CWI64_RS06820	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CWI64_RS06825	COG1122	ATPase activity
CWI64_RS06830	COG1122	ATPase activity
CWI64_RS06835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CWI64_RS06845	COG0612	Peptidase, M16
CWI64_RS06850	COG0612	Peptidase, M16
CWI64_RS06855	COG2501	S4 domain
CWI64_RS06865	COG0516	GMP reductase activity
CWI64_RS06865	COG0517	IMP dehydrogenase activity
CWI64_RS06870	COG0180	Tryptophanyl-tRNA synthetase
CWI64_RS06875	COG0488	(ABC) transporter
CWI64_RS06890	COG1511	domain protein
CWI64_RS06945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CWI64_RS06950	COG1475	DNA binding
CWI64_RS06960	COG0592	DNA-directed DNA polymerase activity
CWI64_RS06970	COG0012	GTP binding
CWI64_RS06980	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CWI64_RS06985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CWI64_RS07010	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CWI64_RS07080	COG0756	dUTP diphosphatase activity
CWI64_RS07090	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CWI64_RS07115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CWI64_RS07130	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWI64_RS07130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CWI64_RS07135	COG1832	CoA-binding protein
CWI64_RS07145	COG2855	membrane
CWI64_RS07150	COG0436	Aminotransferase
CWI64_RS07165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWI64_RS07180	COG2274	protein secretion by the type I secretion system
CWI64_RS07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI64_RS07195	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CWI64_RS07210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CWI64_RS07225	COG0151	Belongs to the GarS family
CWI64_RS07240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CWI64_RS07255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CWI64_RS07260	COG3583	domain protein
CWI64_RS07260	COG3064	Membrane
CWI64_RS07260	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CWI64_RS07275	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS07280	COG3715	PTS system
CWI64_RS07285	COG3716	PTS system mannose fructose sorbose family IID component
CWI64_RS07295	COG2222	sugar isomerase
CWI64_RS07305	COG2514	catechol 2,3-dioxygenase activity
CWI64_RS07310	COG1937	Protein conserved in bacteria
CWI64_RS07340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWI64_RS07345	COG0569	domain protein
CWI64_RS07355	COG1215	transferase activity, transferring glycosyl groups
CWI64_RS07375	COG5002	protein histidine kinase activity
CWI64_RS07400	COG4209	transmembrane transport
CWI64_RS07405	COG0395	ABC-type sugar transport system, permease component
CWI64_RS07455	COG1695	Transcriptional regulator
CWI64_RS07485	COG0546	phosphoglycolate phosphatase activity
CWI64_RS07490	COG1760	l-serine dehydratase
CWI64_RS07495	COG1760	l-serine dehydratase
CWI64_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS07530	COG0137	argininosuccinate synthase activity
CWI64_RS07620	COG0494	nUDIX hydrolase
CWI64_RS07625	COG0445	tRNA wobble uridine modification
CWI64_RS07665	COG1214	PFAM Peptidase M22, glycoprotease
CWI64_RS07675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CWI64_RS07730	COG1396	sequence-specific DNA binding
CWI64_RS07765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS07770	COG1464	Belongs to the NlpA lipoprotein family
CWI64_RS07775	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CWI64_RS07780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CWI64_RS07800	COG2972	Histidine kinase
CWI64_RS07805	COG4753	response regulator
CWI64_RS07805	COG2207	Transcriptional regulator
CWI64_RS07815	COG1780	Probably involved in ribonucleotide reductase function
CWI64_RS07855	COG0019	diaminopimelate decarboxylase activity
CWI64_RS07895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWI64_RS07895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CWI64_RS07915	COG2818	Glycosylase
CWI64_RS07940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CWI64_RS07945	COG0006	proline dipeptidase activity
CWI64_RS07955	COG1393	Belongs to the ArsC family
CWI64_RS07980	COG0285	dihydrofolate synthase activity
CWI64_RS07990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CWI64_RS08020	COG0602	queuosine metabolic process
CWI64_RS08055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CWI64_RS08080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CWI64_RS08120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CWI64_RS08135	COG0201	protein transport
CWI64_RS08145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CWI64_RS08150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CWI64_RS08160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CWI64_RS08165	COG0202	RNA polymerase activity
CWI64_RS08175	COG3830	Belongs to the UPF0237 family
CWI64_RS08200	COG3842	ATPase activity
CWI64_RS08205	COG1840	ABC-type Fe3 transport system, periplasmic component
CWI64_RS08215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CWI64_RS08220	COG1349	DNA-binding transcription factor activity
CWI64_RS08230	COG1447	Phosphotransferase system cellobiose-specific component IIA
CWI64_RS08235	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS08240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS08245	COG1882	Formate acetyltransferase
CWI64_RS08260	COG0495	leucyl-tRNA aminoacylation
CWI64_RS08290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CWI64_RS08295	COG4589	Belongs to the CDS family
CWI64_RS08300	COG0750	zinc metalloprotease
CWI64_RS08310	COG2723	6-phospho-beta-galactosidase activity
CWI64_RS08315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CWI64_RS08325	COG1523	belongs to the glycosyl hydrolase 13 family
CWI64_RS08350	COG2176	DNA-directed DNA polymerase activity
CWI64_RS08370	COG2309	aminopeptidase activity
CWI64_RS08375	COG2261	transglycosylase associated protein
CWI64_RS08380	COG1187	pseudouridine synthase activity
CWI64_RS08390	COG3579	cysteine-type endopeptidase activity
CWI64_RS08395	COG3716	PTS system mannose fructose sorbose family IID component
CWI64_RS08400	COG3715	PTS system
CWI64_RS08410	COG1064	alcohol dehydrogenase
CWI64_RS08415	COG0561	phosphatase activity
CWI64_RS08420	COG2252	PERMEase
CWI64_RS08430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CWI64_RS08435	COG0285	dihydrofolate synthase activity
CWI64_RS08445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CWI64_RS08445	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CWI64_RS08455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CWI64_RS08480	COG2207	Transcriptional regulator
CWI64_RS08480	COG1917	Cupin 2, conserved barrel domain protein
CWI64_RS08500	COG1263	PTS System
CWI64_RS08500	COG2190	(PTS) system
CWI64_RS08500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS08555	COG3493	citrate carrier protein
CWI64_RS08565	COG4565	transcriptional regulatory protein
CWI64_RS08600	COG2723	6-phospho-beta-galactosidase activity
CWI64_RS08615	COG3711	transcriptional antiterminator
CWI64_RS08615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS08630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CWI64_RS08650	COG0386	Belongs to the glutathione peroxidase family
CWI64_RS08655	COG5492	domain, Protein
CWI64_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
CWI64_RS08700	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CWI64_RS08705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS08710	COG3715	PTS system
CWI64_RS08715	COG3716	PTS system mannose fructose sorbose family IID component
CWI64_RS08730	COG1609	Transcriptional regulator
CWI64_RS08760	COG4839	cell division protein FtsL
CWI64_RS08765	COG0768	penicillin binding
CWI64_RS08795	COG0366	Alpha amylase catalytic
CWI64_RS08800	COG4166	transmembrane transport
CWI64_RS08810	COG3344	reverse transcriptase
CWI64_RS08850	COG3475	LICD family
CWI64_RS08870	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CWI64_RS08875	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CWI64_RS08885	COG1088	dTDP-glucose 4,6-dehydratase activity
CWI64_RS08890	COG1091	dTDP-4-dehydrorhamnose reductase activity
CWI64_RS08900	COG4372	Transposase
CWI64_RS08905	COG4372	Transposase
CWI64_RS08915	COG4166	transmembrane transport
CWI64_RS08925	COG0366	Alpha amylase catalytic
CWI64_RS08930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CWI64_RS08955	COG0116	Belongs to the methyltransferase superfamily
CWI64_RS08965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CWI64_RS08970	COG0745	RESPONSE REGULATOR receiver
CWI64_RS09035	COG4585	Histidine kinase
CWI64_RS09040	COG2197	response regulator
CWI64_RS09080	COG2213	PTS system mannitol-specific
CWI64_RS09085	COG3711	transcriptional antiterminator
CWI64_RS09090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS09105	COG0544	peptidyl-prolyl cis-trans isomerase activity
CWI64_RS09110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CWI64_RS09115	COG0681	Belongs to the peptidase S26 family
CWI64_RS09140	COG1115	amino acid carrier protein
CWI64_RS09165	COG0527	aspartate kinase activity
CWI64_RS09175	COG1024	Enoyl-CoA hydratase
CWI64_RS09180	COG1846	Transcriptional regulator
CWI64_RS09190	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CWI64_RS09200	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CWI64_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
CWI64_RS09210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CWI64_RS09225	COG0439	Biotin carboxylase
CWI64_RS09230	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CWI64_RS09270	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CWI64_RS09290	COG1442	glycosyl transferase family 8
CWI64_RS09305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CWI64_RS09315	COG1461	Dihydroxyacetone kinase
CWI64_RS09320	COG0028	Belongs to the TPP enzyme family
CWI64_RS09325	COG0440	acetolactate synthase activity
CWI64_RS09345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CWI64_RS09370	COG0765	amino acid transport
CWI64_RS09400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CWI64_RS09410	COG1882	Formate acetyltransferase
CWI64_RS09445	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CWI64_RS09450	COG0569	domain protein
CWI64_RS09465	COG1122	ATPase activity
CWI64_RS09480	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CWI64_RS09485	COG0671	phosphoesterase, PA-phosphatase related
CWI64_RS09495	COG1247	-acetyltransferase
CWI64_RS09505	COG0504	CTP synthase activity
CWI64_RS09510	COG1283	sodium-dependent phosphate transmembrane transporter activity
CWI64_RS09530	COG0789	Transcriptional regulator
CWI64_RS09535	COG0174	glutamine synthetase
CWI64_RS09560	COG4974	Belongs to the 'phage' integrase family
CWI64_RS09570	COG0732	type I restriction modification DNA specificity domain
CWI64_RS09620	COG0484	heat shock protein binding
CWI64_RS09630	COG0537	adenosine 5'-monophosphoramidase activity
CWI64_RS09635	COG1131	(ABC) transporter
CWI64_RS09665	COG3290	protein histidine kinase activity
CWI64_RS09675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI64_RS09740	COG1266	CAAX protease self-immunity
CWI64_RS09760	COG0195	Participates in both transcription termination and antitermination
CWI64_RS09765	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CWI64_RS09775	COG3064	Membrane
CWI64_RS09775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CWI64_RS09825	COG0519	Catalyzes the synthesis of GMP from XMP
CWI64_RS09835	COG0525	valine-tRNA ligase activity
CWI64_RS09865	COG3711	transcriptional antiterminator
CWI64_RS09870	COG2190	(PTS) system
CWI64_RS09870	COG1263	PTS System
CWI64_RS09870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS09885	COG0456	acetyltransferase
CWI64_RS09890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI64_RS09890	COG0072	phenylalanine-tRNA ligase activity
CWI64_RS09905	COG3620	sequence-specific DNA binding
CWI64_RS09910	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CWI64_RS09930	COG1045	serine acetyltransferase
CWI64_RS09945	COG0215	cysteine-tRNA ligase activity
CWI64_RS09950	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CWI64_RS09970	COG0577	efflux transmembrane transporter activity
CWI64_RS09975	COG1136	(ABC) transporter
CWI64_RS09980	COG0577	efflux transmembrane transporter activity
CWI64_RS09985	COG0745	RESPONSE REGULATOR receiver
CWI64_RS09990	COG5002	protein histidine kinase activity
CWI64_RS09995	COG0191	fructose-bisphosphate aldolase activity
CWI64_RS10000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CWI64_RS10005	COG0765	amino acid transport
CWI64_RS10010	COG0765	amino acid transport
CWI64_RS10015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS10025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CWI64_RS10025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CWI64_RS10065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS10080	COG1573	uracil-dna glycosylase
CWI64_RS10095	COG1114	Component of the transport system for branched-chain amino acids
CWI64_RS10100	COG1363	Peptidase, m42
CWI64_RS10150	COG4555	ABC transporter
CWI64_RS10175	COG1404	Belongs to the peptidase S8 family
CWI64_RS10190	COG3775	system Galactitol-specific IIC component
CWI64_RS10200	COG3250	beta-galactosidase activity
CWI64_RS10230	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CWI64_RS10250	COG0785	Cytochrome C biogenesis protein
CWI64_RS10255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CWI64_RS10260	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI64_RS10260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CWI64_RS10270	COG2207	Transcriptional regulator
CWI64_RS10270	COG4753	response regulator
CWI64_RS10275	COG2972	Histidine kinase
CWI64_RS10285	COG3064	Membrane
CWI64_RS10290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CWI64_RS10305	COG1940	carbohydrate kinase activity
CWI64_RS10325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CWI64_RS10330	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CWI64_RS10340	COG0300	oxidoreductase activity
CWI64_RS10355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CWI64_RS10365	COG1187	pseudouridine synthase activity
CWI64_RS10390	COG1136	(ABC) transporter
CWI64_RS10405	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CWI64_RS10445	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CWI64_RS10470	COG1131	(ABC) transporter
CWI64_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CWI64_RS10485	COG0765	amino acid transport
CWI64_RS10490	COG1304	FMN binding
CWI64_RS10505	COG1304	FMN binding
CWI64_RS10530	COG0352	thiamine-phosphate diphosphorylase activity
CWI64_RS10545	COG4172	Belongs to the ABC transporter superfamily
CWI64_RS10555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CWI64_RS10570	COG0352	thiamine-phosphate diphosphorylase activity
CWI64_RS10590	COG2217	Heavy metal translocating P-type atpase
CWI64_RS10595	COG0028	Belongs to the TPP enzyme family
CWI64_RS10610	COG2723	6-phospho-beta-galactosidase activity
CWI64_RS10615	COG1482	cell wall glycoprotein biosynthetic process
CWI64_RS10625	COG0789	Transcriptional regulator
CWI64_RS10635	COG2081	HI0933 family
CWI64_RS10640	COG1307	EDD domain protein, DegV family
CWI64_RS10650	COG2131	deaminase
CWI64_RS10655	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CWI64_RS10700	COG0517	IMP dehydrogenase activity
CWI64_RS10700	COG0617	tRNA 3'-terminal CCA addition
CWI64_RS10700	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CWI64_RS10710	COG2884	Cell division ATP-binding protein ftsE
CWI64_RS10715	COG2177	Part of the ABC transporter FtsEX involved in
CWI64_RS10720	COG2190	(PTS) system
CWI64_RS10720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CWI64_RS10720	COG1263	PTS System
CWI64_RS10730	COG0513	Belongs to the DEAD box helicase family
CWI64_RS10745	COG0167	dihydroorotate dehydrogenase activity
CWI64_RS10755	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CWI64_RS10760	COG4470	Protein conserved in bacteria
CWI64_RS10765	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CWI64_RS10775	COG0488	(ABC) transporter
CWI64_RS10805	COG1837	Belongs to the UPF0109 family
CWI64_RS10830	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CWI64_RS10830	COG1328	CTP reductase activity
CWI64_RS10840	COG4443	Transcriptional Coactivator p15 (PC4)
CWI64_RS10850	COG1268	BioY protein
CWI64_RS10855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CWI64_RS10860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CWI64_RS10865	COG1136	(ABC) transporter
CWI64_RS10870	COG0577	efflux transmembrane transporter activity
CWI64_RS10880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI64_RS10880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CWI64_RS10900	COG4989	oxidoreductase activity
CWI64_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
CWI64_RS10935	COG0745	RESPONSE REGULATOR receiver
CWI64_RS10940	COG5002	protein histidine kinase activity
CWI64_RS10965	COG0772	Belongs to the SEDS family
CWI64_RS10970	COG0693	protein deglycase activity
CWI64_RS10980	COG0187	DNA topoisomerase II activity
CWI64_RS11015	COG0494	nUDIX hydrolase
CWI64_RS11025	COG0542	response to heat
CWI64_RS11030	COG4703	Protein of unknown function (DUF1797)
CWI64_RS11035	COG0765	amino acid transport
CWI64_RS11040	COG1126	abc transporter atp-binding protein
CWI64_RS11045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CWI64_RS11050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CWI64_RS11070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CWI64_RS11115	COG1072	(Pantothenic acid kinase))
CWI64_RS11125	COG2813	Specifically methylates the guanine in position
CWI64_RS11130	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CWI64_RS11140	COG0295	cytidine deaminase activity
CWI64_RS11145	COG1744	ABC transporter substrate-binding protein PnrA-like
CWI64_RS11175	COG0187	DNA topoisomerase II activity
CWI64_RS11180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CWI64_RS11185	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CWI64_RS11190	COG4166	transmembrane transport
CWI64_RS11225	COG0539	negative regulation of cytoplasmic translation
CWI64_RS11235	COG1956	GAF domain-containing protein
CWI64_RS11240	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CWI64_RS11255	COG0719	Fe-S assembly protein
CWI64_RS11260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CWI64_RS11270	COG0719	Fe-S assembly protein
CWI64_RS11275	COG1686	Belongs to the peptidase S11 family
CWI64_RS11280	COG0628	permease
CWI64_RS11295	COG1349	DNA-binding transcription factor activity
CWI64_RS11300	COG1105	Belongs to the carbohydrate kinase PfkB family
CWI64_RS11305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CWI64_RS11305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI64_RS11305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CWI64_RS11310	COG1674	ftsk spoiiie
CWI64_RS11310	COG0697	spore germination
CWI64_RS11320	COG1104	cysteine desulfurase activity
CWI64_RS11375	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
CWI64_RS11585	COG0560	Phosphoserine phosphatase
CWI64_RS11590	COG0560	Phosphoserine phosphatase
CWI64_RS11620	COG2801	Transposase and inactivated derivatives
CWI64_RS11700	COG2801	Transposase and inactivated derivatives
CWI64_RS11705	COG2801	Transposase and inactivated derivatives