locus-tag	class	description
L1A11_RS00010	COG0592	DNA-directed DNA polymerase activity
L1A11_RS00020	COG0012	GTP binding
L1A11_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L1A11_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L1A11_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
L1A11_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L1A11_RS00145	COG1131	(ABC) transporter
L1A11_RS00150	COG0842	Transport permease protein
L1A11_RS00155	COG4585	Histidine kinase
L1A11_RS00160	COG2197	response regulator
L1A11_RS00165	COG1609	Transcriptional regulator
L1A11_RS00175	COG0252	asparaginase activity
L1A11_RS00180	COG0561	phosphatase activity
L1A11_RS00185	COG0589	response to stress
L1A11_RS00195	COG0436	Aminotransferase
L1A11_RS00210	COG0084	hydrolase, TatD family'
L1A11_RS00215	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
L1A11_RS00250	COG1162	GTPase activity
L1A11_RS00260	COG1564	THIamine pyrophosphokinase
L1A11_RS00275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
L1A11_RS00285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L1A11_RS00295	COG1254	Belongs to the acylphosphatase family
L1A11_RS00300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L1A11_RS00315	COG0742	ribosomal rna small subunit methyltransferase
L1A11_RS00325	COG3480	Lon protease (S16) C-terminal proteolytic domain
L1A11_RS00335	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L1A11_RS00350	COG1253	flavin adenine dinucleotide binding
L1A11_RS00375	COG0577	efflux transmembrane transporter activity
L1A11_RS00375	COG1136	(ABC) transporter
L1A11_RS00395	COG0802	atpase or kinase
L1A11_RS00405	COG1316	TRANSCRIPTIONal
L1A11_RS00425	COG5632	N-Acetylmuramoyl-L-alanine amidase
L1A11_RS00425	COG5263	repeat protein
L1A11_RS00510	COG1132	(ABC) transporter
L1A11_RS00550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1A11_RS00555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1A11_RS00560	COG4221	oxidoreductase activity
L1A11_RS00570	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
L1A11_RS00610	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1A11_RS00675	COG0756	dUTP diphosphatase activity
L1A11_RS00685	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
L1A11_RS00700	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L1A11_RS00715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1A11_RS00715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
L1A11_RS00720	COG1832	CoA-binding protein
L1A11_RS00730	COG2855	membrane
L1A11_RS00735	COG0436	Aminotransferase
L1A11_RS00765	COG2274	protein secretion by the type I secretion system
L1A11_RS00770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1A11_RS00780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L1A11_RS00785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
L1A11_RS00795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L1A11_RS00810	COG0151	Belongs to the GarS family
L1A11_RS00820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
L1A11_RS00835	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L1A11_RS00840	COG3583	domain protein
L1A11_RS00840	COG3064	Membrane
L1A11_RS00840	COG3525	Glycosyl hydrolase, family 20, catalytic domain
L1A11_RS00855	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS00860	COG3715	PTS system
L1A11_RS00865	COG3716	PTS system mannose fructose sorbose family IID component
L1A11_RS00875	COG2222	sugar isomerase
L1A11_RS00885	COG2514	catechol 2,3-dioxygenase activity
L1A11_RS00890	COG1937	Protein conserved in bacteria
L1A11_RS00915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1A11_RS00920	COG0569	domain protein
L1A11_RS00950	COG5002	protein histidine kinase activity
L1A11_RS00980	COG4209	transmembrane transport
L1A11_RS00985	COG0395	ABC-type sugar transport system, permease component
L1A11_RS00990	COG1653	transport
L1A11_RS01020	COG1695	Transcriptional regulator
L1A11_RS01045	COG0546	phosphoglycolate phosphatase activity
L1A11_RS01050	COG1760	l-serine dehydratase
L1A11_RS01055	COG1760	l-serine dehydratase
L1A11_RS01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS01125	COG2274	protein secretion by the type I secretion system
L1A11_RS01220	COG0445	tRNA wobble uridine modification
L1A11_RS01250	COG1214	PFAM Peptidase M22, glycoprotease
L1A11_RS01260	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
L1A11_RS01280	COG0438	transferase activity, transferring glycosyl groups
L1A11_RS01315	COG1396	sequence-specific DNA binding
L1A11_RS01350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS01355	COG1464	Belongs to the NlpA lipoprotein family
L1A11_RS01360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L1A11_RS01365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L1A11_RS01385	COG2972	Histidine kinase
L1A11_RS01390	COG4753	response regulator
L1A11_RS01390	COG2207	Transcriptional regulator
L1A11_RS01400	COG1780	Probably involved in ribonucleotide reductase function
L1A11_RS01430	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1A11_RS01430	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L1A11_RS01450	COG2818	Glycosylase
L1A11_RS01475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L1A11_RS01480	COG0006	proline dipeptidase activity
L1A11_RS01485	COG1393	Belongs to the ArsC family
L1A11_RS01510	COG0285	dihydrofolate synthase activity
L1A11_RS01520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L1A11_RS01585	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
L1A11_RS01610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
L1A11_RS01650	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
L1A11_RS01665	COG0201	protein transport
L1A11_RS01675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
L1A11_RS01680	COG0257	Belongs to the bacterial ribosomal protein bL36 family
L1A11_RS01690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
L1A11_RS01695	COG0202	RNA polymerase activity
L1A11_RS01705	COG3830	Belongs to the UPF0237 family
L1A11_RS01725	COG3842	ATPase activity
L1A11_RS01740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
L1A11_RS01745	COG1349	DNA-binding transcription factor activity
L1A11_RS01755	COG1447	Phosphotransferase system cellobiose-specific component IIA
L1A11_RS01760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS01765	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS01770	COG1882	Formate acetyltransferase
L1A11_RS01820	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L1A11_RS01825	COG4589	Belongs to the CDS family
L1A11_RS01830	COG0750	zinc metalloprotease
L1A11_RS01840	COG2723	6-phospho-beta-galactosidase activity
L1A11_RS01845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L1A11_RS01855	COG1523	belongs to the glycosyl hydrolase 13 family
L1A11_RS01875	COG2176	DNA-directed DNA polymerase activity
L1A11_RS01895	COG2309	aminopeptidase activity
L1A11_RS01900	COG2261	transglycosylase associated protein
L1A11_RS01905	COG1187	pseudouridine synthase activity
L1A11_RS01910	COG3579	cysteine-type endopeptidase activity
L1A11_RS01915	COG3716	PTS system mannose fructose sorbose family IID component
L1A11_RS01920	COG3715	PTS system
L1A11_RS01930	COG1064	alcohol dehydrogenase
L1A11_RS01935	COG0561	phosphatase activity
L1A11_RS01940	COG2252	PERMEase
L1A11_RS01950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L1A11_RS01955	COG0285	dihydrofolate synthase activity
L1A11_RS01960	COG0302	gtp cyclohydrolase
L1A11_RS01965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
L1A11_RS01965	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L1A11_RS01975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
L1A11_RS01990	COG2723	6-phospho-beta-galactosidase activity
L1A11_RS02005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1A11_RS02005	COG3711	transcriptional antiterminator
L1A11_RS02020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS02035	COG0386	Belongs to the glutathione peroxidase family
L1A11_RS02055	COG0800	Aldolase
L1A11_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
L1A11_RS02080	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
L1A11_RS02085	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS02090	COG3715	PTS system
L1A11_RS02095	COG3716	PTS system mannose fructose sorbose family IID component
L1A11_RS02110	COG1609	Transcriptional regulator
L1A11_RS02140	COG4839	cell division protein FtsL
L1A11_RS02145	COG0768	penicillin binding
L1A11_RS02170	COG0366	Alpha amylase catalytic
L1A11_RS02175	COG4166	transmembrane transport
L1A11_RS02245	COG0366	Alpha amylase catalytic
L1A11_RS02250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1A11_RS02275	COG0116	Belongs to the methyltransferase superfamily
L1A11_RS02285	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
L1A11_RS02290	COG0745	RESPONSE REGULATOR receiver
L1A11_RS02350	COG4585	Histidine kinase
L1A11_RS02355	COG2197	response regulator
L1A11_RS02375	COG0582	viral genome integration into host DNA
L1A11_RS02385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L1A11_RS02390	COG0681	Belongs to the peptidase S26 family
L1A11_RS02415	COG1115	amino acid carrier protein
L1A11_RS02430	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
L1A11_RS02440	COG0527	aspartate kinase activity
L1A11_RS02445	COG1024	Enoyl-CoA hydratase
L1A11_RS02450	COG1846	Transcriptional regulator
L1A11_RS02460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L1A11_RS02470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L1A11_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
L1A11_RS02480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L1A11_RS02495	COG0439	Biotin carboxylase
L1A11_RS02500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
L1A11_RS02560	COG1442	glycosyl transferase family 8
L1A11_RS02570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
L1A11_RS02580	COG1461	Dihydroxyacetone kinase
L1A11_RS02585	COG0028	Belongs to the TPP enzyme family
L1A11_RS02590	COG0440	acetolactate synthase activity
L1A11_RS02610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L1A11_RS02625	COG0765	amino acid transport
L1A11_RS02645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L1A11_RS02650	COG1882	Formate acetyltransferase
L1A11_RS02675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L1A11_RS02680	COG0569	domain protein
L1A11_RS02700	COG1122	ATPase activity
L1A11_RS02715	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
L1A11_RS02720	COG0671	phosphoesterase, PA-phosphatase related
L1A11_RS02730	COG1247	-acetyltransferase
L1A11_RS02740	COG0504	CTP synthase activity
L1A11_RS02745	COG1283	sodium-dependent phosphate transmembrane transporter activity
L1A11_RS02765	COG0789	Transcriptional regulator
L1A11_RS02770	COG0174	glutamine synthetase
L1A11_RS02790	COG0732	type I restriction modification DNA specificity domain
L1A11_RS02795	COG4974	Belongs to the 'phage' integrase family
L1A11_RS02815	COG0732	type I restriction modification DNA specificity domain
L1A11_RS02855	COG0484	heat shock protein binding
L1A11_RS02870	COG0537	adenosine 5'-monophosphoramidase activity
L1A11_RS02875	COG1131	(ABC) transporter
L1A11_RS02880	COG4473	ABC transporter
L1A11_RS02900	COG3290	protein histidine kinase activity
L1A11_RS02910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L1A11_RS02950	COG1266	CAAX protease self-immunity
L1A11_RS02970	COG0195	Participates in both transcription termination and antitermination
L1A11_RS02975	COG2740	Nucleic-acid-binding protein implicated in transcription termination
L1A11_RS03035	COG0519	Catalyzes the synthesis of GMP from XMP
L1A11_RS03045	COG0525	valine-tRNA ligase activity
L1A11_RS03065	COG3711	transcriptional antiterminator
L1A11_RS03070	COG2190	(PTS) system
L1A11_RS03070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS03070	COG1263	PTS System
L1A11_RS03090	COG0456	acetyltransferase
L1A11_RS03095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1A11_RS03095	COG0072	phenylalanine-tRNA ligase activity
L1A11_RS03110	COG3620	sequence-specific DNA binding
L1A11_RS03115	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
L1A11_RS03130	COG1045	serine acetyltransferase
L1A11_RS03140	COG0215	cysteine-tRNA ligase activity
L1A11_RS03145	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
L1A11_RS03165	COG0577	efflux transmembrane transporter activity
L1A11_RS03170	COG1136	(ABC) transporter
L1A11_RS03175	COG0577	efflux transmembrane transporter activity
L1A11_RS03185	COG0745	RESPONSE REGULATOR receiver
L1A11_RS03190	COG5002	protein histidine kinase activity
L1A11_RS03195	COG0191	fructose-bisphosphate aldolase activity
L1A11_RS03205	COG0765	amino acid transport
L1A11_RS03210	COG0765	amino acid transport
L1A11_RS03215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS03225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L1A11_RS03225	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
L1A11_RS03255	COG0322	excinuclease ABC activity
L1A11_RS03265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS03280	COG1573	uracil-dna glycosylase
L1A11_RS03290	COG1114	Component of the transport system for branched-chain amino acids
L1A11_RS03295	COG1363	Peptidase, m42
L1A11_RS03340	COG4555	ABC transporter
L1A11_RS03370	COG1404	Belongs to the peptidase S8 family
L1A11_RS03385	COG3775	system Galactitol-specific IIC component
L1A11_RS03395	COG3250	beta-galactosidase activity
L1A11_RS03420	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
L1A11_RS03440	COG0785	Cytochrome C biogenesis protein
L1A11_RS03445	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1A11_RS03450	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1A11_RS03450	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1A11_RS03455	COG2207	Transcriptional regulator
L1A11_RS03455	COG4753	response regulator
L1A11_RS03460	COG2972	Histidine kinase
L1A11_RS03470	COG3064	Membrane
L1A11_RS03475	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L1A11_RS03490	COG1940	carbohydrate kinase activity
L1A11_RS03505	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
L1A11_RS03510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L1A11_RS03515	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
L1A11_RS03525	COG0300	oxidoreductase activity
L1A11_RS03540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
L1A11_RS03550	COG1187	pseudouridine synthase activity
L1A11_RS03555	COG1217	gtp-binding protein TYPA
L1A11_RS03575	COG1136	(ABC) transporter
L1A11_RS03590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L1A11_RS03600	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
L1A11_RS03620	COG1131	(ABC) transporter
L1A11_RS03625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS03635	COG4215	(ABC) transporter
L1A11_RS03640	COG4597	amino acid ABC transporter
L1A11_RS03645	COG1304	FMN binding
L1A11_RS03655	COG1304	FMN binding
L1A11_RS03670	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
L1A11_RS03675	COG0352	thiamine-phosphate diphosphorylase activity
L1A11_RS03685	COG4172	Belongs to the ABC transporter superfamily
L1A11_RS03695	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L1A11_RS03710	COG0352	thiamine-phosphate diphosphorylase activity
L1A11_RS03730	COG2217	Heavy metal translocating P-type atpase
L1A11_RS03735	COG0028	Belongs to the TPP enzyme family
L1A11_RS03755	COG1482	cell wall glycoprotein biosynthetic process
L1A11_RS03775	COG2081	HI0933 family
L1A11_RS03780	COG1307	EDD domain protein, DegV family
L1A11_RS03790	COG2131	deaminase
L1A11_RS03795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
L1A11_RS03835	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L1A11_RS03835	COG0617	tRNA 3'-terminal CCA addition
L1A11_RS03835	COG0517	IMP dehydrogenase activity
L1A11_RS03845	COG2884	Cell division ATP-binding protein ftsE
L1A11_RS03850	COG2177	Part of the ABC transporter FtsEX involved in
L1A11_RS03855	COG1263	PTS System
L1A11_RS03855	COG2190	(PTS) system
L1A11_RS03855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS03865	COG0513	Belongs to the DEAD box helicase family
L1A11_RS03875	COG0167	dihydroorotate dehydrogenase activity
L1A11_RS03885	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L1A11_RS03890	COG4470	Protein conserved in bacteria
L1A11_RS03905	COG0488	(ABC) transporter
L1A11_RS03910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L1A11_RS03930	COG1837	Belongs to the UPF0109 family
L1A11_RS03955	COG1328	CTP reductase activity
L1A11_RS03955	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
L1A11_RS03965	COG4443	Transcriptional Coactivator p15 (PC4)
L1A11_RS03975	COG1268	BioY protein
L1A11_RS03980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1A11_RS03990	COG1136	(ABC) transporter
L1A11_RS03995	COG0577	efflux transmembrane transporter activity
L1A11_RS04000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1A11_RS04000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L1A11_RS04015	COG4989	oxidoreductase activity
L1A11_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
L1A11_RS04055	COG0745	RESPONSE REGULATOR receiver
L1A11_RS04060	COG5002	protein histidine kinase activity
L1A11_RS04080	COG0772	Belongs to the SEDS family
L1A11_RS04085	COG0693	protein deglycase activity
L1A11_RS04095	COG0187	DNA topoisomerase II activity
L1A11_RS04115	COG0494	nUDIX hydrolase
L1A11_RS04125	COG0542	response to heat
L1A11_RS04130	COG4703	Protein of unknown function (DUF1797)
L1A11_RS04135	COG0765	amino acid transport
L1A11_RS04140	COG1126	abc transporter atp-binding protein
L1A11_RS04145	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
L1A11_RS04150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L1A11_RS04170	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
L1A11_RS04215	COG2813	Specifically methylates the guanine in position
L1A11_RS04220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
L1A11_RS04230	COG0295	cytidine deaminase activity
L1A11_RS04235	COG1744	ABC transporter substrate-binding protein PnrA-like
L1A11_RS04240	COG3845	ABC transporter
L1A11_RS04245	COG4603	Belongs to the binding-protein-dependent transport system permease family
L1A11_RS04250	COG1079	Belongs to the binding-protein-dependent transport system permease family
L1A11_RS04270	COG0187	DNA topoisomerase II activity
L1A11_RS04275	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L1A11_RS04280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L1A11_RS04285	COG4166	transmembrane transport
L1A11_RS04320	COG0539	negative regulation of cytoplasmic translation
L1A11_RS04330	COG1956	GAF domain-containing protein
L1A11_RS04335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L1A11_RS04350	COG0719	Fe-S assembly protein
L1A11_RS04355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L1A11_RS04365	COG0719	Fe-S assembly protein
L1A11_RS04370	COG1686	Belongs to the peptidase S11 family
L1A11_RS04375	COG0628	permease
L1A11_RS04390	COG1349	DNA-binding transcription factor activity
L1A11_RS04395	COG1105	Belongs to the carbohydrate kinase PfkB family
L1A11_RS04400	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1A11_RS04400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1A11_RS04400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1A11_RS04405	COG1674	ftsk spoiiie
L1A11_RS04405	COG0697	spore germination
L1A11_RS04415	COG1104	cysteine desulfurase activity
L1A11_RS04480	COG1438	arginine binding
L1A11_RS04500	COG0469	pyruvate kinase activity
L1A11_RS04505	COG0582	viral genome integration into host DNA
L1A11_RS04535	COG3689	TIGRFAM TIGR03943 family protein
L1A11_RS04540	COG0701	Predicted permease
L1A11_RS04550	COG2183	response to ionizing radiation
L1A11_RS04570	COG1136	(ABC) transporter
L1A11_RS04575	COG0577	efflux transmembrane transporter activity
L1A11_RS04590	COG1982	Orn Lys Arg decarboxylase major
L1A11_RS04610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
L1A11_RS04630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L1A11_RS04635	COG0561	phosphatase activity
L1A11_RS04655	COG0583	DNA-binding transcription factor activity
L1A11_RS04660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
L1A11_RS04665	COG0564	pseudouridine synthase activity
L1A11_RS04670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
L1A11_RS04685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
L1A11_RS04695	COG0470	DNA polymerase III
L1A11_RS04740	COG0528	UMP kinase activity
L1A11_RS04750	COG2996	Protein conserved in bacteria
L1A11_RS04760	COG1702	phosphate starvation-inducible protein PhoH
L1A11_RS04780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L1A11_RS04785	COG1596	polysaccharide export
L1A11_RS04785	COG1555	photosystem II stabilization
L1A11_RS04790	COG2333	competence protein COMEC
L1A11_RS04790	COG0658	competence protein
L1A11_RS04800	COG1131	(ABC) transporter
L1A11_RS04830	COG0543	2 iron, 2 sulfur cluster binding
L1A11_RS04835	COG0167	dihydroorotate dehydrogenase activity
L1A11_RS04840	COG4193	domain, Protein
L1A11_RS04840	COG5263	repeat protein
L1A11_RS04845	COG1293	RNA-binding protein homologous to eukaryotic snRNP
L1A11_RS04855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
L1A11_RS04865	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
L1A11_RS04870	COG0237	dephospho-CoA kinase activity
L1A11_RS04875	COG2814	Major facilitator Superfamily
L1A11_RS04880	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1A11_RS04890	COG0557	exoribonuclease II activity
L1A11_RS04900	COG3615	Tellurite resistance protein tehB
L1A11_RS04900	COG0500	methyltransferase
L1A11_RS04915	COG4122	O-methyltransferase activity
L1A11_RS04940	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L1A11_RS04960	COG0494	nUDIX hydrolase
L1A11_RS04970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L1A11_RS04980	COG2176	DNA-directed DNA polymerase activity
L1A11_RS04985	COG0584	glycerophosphoryl diester phosphodiesterase
L1A11_RS05005	COG0785	Cytochrome C biogenesis protein
L1A11_RS05010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
L1A11_RS05015	COG0531	amino acid
L1A11_RS05020	COG3443	Belongs to the bacterial solute-binding protein 9 family
L1A11_RS05020	COG0803	Belongs to the bacterial solute-binding protein 9 family
L1A11_RS05060	COG1970	mechanosensitive ion channel activity
L1A11_RS05070	COG4708	membrane
L1A11_RS05080	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
L1A11_RS05090	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
L1A11_RS05095	COG1942	4-Oxalocrotonate Tautomerase
L1A11_RS05100	COG1435	thymidine kinase activity
L1A11_RS05105	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
L1A11_RS05110	COG2890	protein-(glutamine-N5) methyltransferase activity
L1A11_RS05135	COG0741	lytic transglycosylase activity
L1A11_RS05145	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
L1A11_RS05165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1A11_RS05170	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1A11_RS05225	COG1597	lipid kinase activity
L1A11_RS05230	COG0366	Alpha amylase catalytic
L1A11_RS05240	COG1396	sequence-specific DNA binding
L1A11_RS05245	COG0542	response to heat
L1A11_RS05250	COG0613	PHP domain protein
L1A11_RS05270	COG1181	Belongs to the D-alanine--D-alanine ligase family
L1A11_RS05275	COG0148	phosphopyruvate hydratase activity
L1A11_RS05280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L1A11_RS05285	COG3959	Transketolase, thiamine diphosphate binding domain
L1A11_RS05290	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L1A11_RS05295	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L1A11_RS05305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L1A11_RS05320	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
L1A11_RS05320	COG0028	Belongs to the TPP enzyme family
L1A11_RS05335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L1A11_RS05345	COG4555	ABC transporter
L1A11_RS05370	COG1396	sequence-specific DNA binding
L1A11_RS05400	COG0772	Belongs to the SEDS family
L1A11_RS05405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
L1A11_RS05420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L1A11_RS05425	COG0358	DNA primase activity
L1A11_RS05430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
L1A11_RS05435	COG2151	metal-sulfur cluster biosynthetic enzyme
L1A11_RS05440	COG0438	transferase activity, transferring glycosyl groups
L1A11_RS05445	COG0438	transferase activity, transferring glycosyl groups
L1A11_RS05470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L1A11_RS05480	COG4109	DRTGG domain
L1A11_RS05485	COG0024	Methionine aminopeptidase
L1A11_RS05495	COG0210	DNA helicase
L1A11_RS05505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L1A11_RS05525	COG1104	cysteine desulfurase activity
L1A11_RS05530	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L1A11_RS05540	COG2357	RelA SpoT domain protein
L1A11_RS05550	COG0564	pseudouridine synthase activity
L1A11_RS05555	COG0280	phosphate acetyltransferase
L1A11_RS05590	COG0196	riboflavin kinase activity
L1A11_RS05595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1A11_RS05600	COG1307	EDD domain protein, DegV family
L1A11_RS05610	COG0488	(ABC) transporter
L1A11_RS05630	COG1523	belongs to the glycosyl hydrolase 13 family
L1A11_RS05635	COG1012	belongs to the aldehyde dehydrogenase family
L1A11_RS05640	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
L1A11_RS05650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
L1A11_RS05660	COG0560	Phosphoserine phosphatase
L1A11_RS05665	COG0560	Phosphoserine phosphatase
L1A11_RS05685	COG0582	viral genome integration into host DNA
L1A11_RS05710	COG1074	ATP-dependent DNA helicase activity
L1A11_RS05730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L1A11_RS05735	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L1A11_RS05750	COG0095	Lipoate-protein ligase
L1A11_RS05755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1A11_RS05760	COG0508	dehydrogenase complex catalyzes the overall conversion of
L1A11_RS05765	COG0022	dehydrogenase e1 component
L1A11_RS05770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L1A11_RS05775	COG0534	Mate efflux family protein
L1A11_RS05785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
L1A11_RS05790	COG1051	belongs to the nudix hydrolase family
L1A11_RS05805	COG1011	Hydrolase
L1A11_RS05810	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
L1A11_RS05825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1A11_RS05830	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L1A11_RS05835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1A11_RS05840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L1A11_RS05870	COG3711	transcriptional antiterminator
L1A11_RS05875	COG3684	Belongs to the aldolase LacD family
L1A11_RS05925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L1A11_RS05930	COG0497	DNA recombination
L1A11_RS05935	COG1438	arginine binding
L1A11_RS05940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
L1A11_RS05970	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L1A11_RS05990	COG3764	Sortase (surface protein transpeptidase)
L1A11_RS05995	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
L1A11_RS06005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L1A11_RS06020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
L1A11_RS06025	COG5002	protein histidine kinase activity
L1A11_RS06030	COG0745	RESPONSE REGULATOR receiver
L1A11_RS06035	COG1194	a g-specific adenine glycosylase
L1A11_RS06050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L1A11_RS06055	COG4684	Psort location CytoplasmicMembrane, score
L1A11_RS06065	COG1827	regulation of RNA biosynthetic process
L1A11_RS06095	COG0765	amino acid transport
L1A11_RS06100	COG1126	abc transporter atp-binding protein
L1A11_RS06105	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
L1A11_RS06110	COG0552	protein localization to endoplasmic reticulum
L1A11_RS06115	COG0561	phosphatase activity
L1A11_RS06120	COG0561	phosphatase activity
L1A11_RS06125	COG1196	nuclear chromosome segregation
L1A11_RS06150	COG1401	restriction endodeoxyribonuclease activity
L1A11_RS06160	COG0066	3-isopropylmalate dehydratase activity
L1A11_RS06190	COG3142	Participates in the control of copper homeostasis
L1A11_RS06195	COG2832	Protein of unknown function (DUF454)
L1A11_RS06200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
L1A11_RS06210	COG0758	DNA mediated transformation
L1A11_RS06215	COG4750	Nucleotidyl transferase
L1A11_RS06230	COG1063	alcohol dehydrogenase
L1A11_RS06245	COG3475	LICD family
L1A11_RS06250	COG3475	LICD family
L1A11_RS06260	COG0505	Belongs to the CarA family
L1A11_RS06275	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L1A11_RS06290	COG0488	(ABC) transporter
L1A11_RS06300	COG1704	LemA family
L1A11_RS06315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L1A11_RS06330	COG1078	dGTPase activity
L1A11_RS06350	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L1A11_RS06355	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
L1A11_RS06360	COG0077	Prephenate dehydratase
L1A11_RS06360	COG1605	Chorismate mutase
L1A11_RS06365	COG0716	FMN binding
L1A11_RS06370	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
L1A11_RS06390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L1A11_RS06435	COG1136	(ABC) transporter
L1A11_RS06435	COG0577	efflux transmembrane transporter activity
L1A11_RS06445	COG0515	serine threonine protein kinase
L1A11_RS06495	COG0402	S-adenosylhomocysteine deaminase activity
L1A11_RS06510	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1A11_RS06510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
L1A11_RS06540	COG1215	transferase activity, transferring glycosyl groups
L1A11_RS06550	COG3475	LICD family
L1A11_RS06560	COG0077	Prephenate dehydratase
L1A11_RS06565	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
L1A11_RS06580	COG0287	Prephenate dehydrogenase
L1A11_RS06605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
L1A11_RS06615	COG1131	(ABC) transporter
L1A11_RS06655	COG3842	ATPase activity
L1A11_RS06670	COG3527	Alpha-acetolactate decarboxylase
L1A11_RS06675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L1A11_RS06680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS06685	COG0704	Plays a role in the regulation of phosphate uptake
L1A11_RS06690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L1A11_RS06695	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L1A11_RS06700	COG0581	inorganic phosphate transmembrane transporter activity
L1A11_RS06705	COG0573	inorganic phosphate transmembrane transporter activity
L1A11_RS06710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L1A11_RS06715	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1A11_RS06715	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
L1A11_RS06720	COG0483	inositol monophosphate 1-phosphatase activity
L1A11_RS06730	COG1393	Belongs to the ArsC family
L1A11_RS06740	COG0647	UMP catabolic process
L1A11_RS06750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L1A11_RS06785	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
L1A11_RS06795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
L1A11_RS06805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
L1A11_RS06850	COG0826	peptidase U32
L1A11_RS06870	COG1132	(ABC) transporter
L1A11_RS06875	COG1132	(ABC) transporter
L1A11_RS06890	COG1129	ABC transporter
L1A11_RS06925	COG2188	Transcriptional regulator
L1A11_RS06930	COG0697	spore germination
L1A11_RS06935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L1A11_RS06950	COG0561	phosphatase activity
L1A11_RS06970	COG0492	ferredoxin-NADP+ reductase activity
L1A11_RS06980	COG1126	abc transporter atp-binding protein
L1A11_RS06990	COG1393	Belongs to the ArsC family
L1A11_RS06995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L1A11_RS07010	COG1272	protein, Hemolysin III
L1A11_RS07040	COG3976	FMN-binding domain protein
L1A11_RS07040	COG1053	succinate dehydrogenase
L1A11_RS07040	COG0431	NADPH-dependent FMN reductase
L1A11_RS07050	COG0751	glycine-tRNA ligase activity
L1A11_RS07065	COG0656	L-ascorbic acid biosynthetic process
L1A11_RS07070	COG0726	polysaccharide deacetylase
L1A11_RS07105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L1A11_RS07140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L1A11_RS07150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L1A11_RS07155	COG1126	abc transporter atp-binding protein
L1A11_RS07170	COG0628	permease
L1A11_RS07175	COG2706	6-phosphogluconolactonase activity
L1A11_RS07190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
L1A11_RS07235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L1A11_RS07260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
L1A11_RS07265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
L1A11_RS07270	COG0626	cystathionine gamma-synthase activity
L1A11_RS07275	COG1132	(ABC) transporter
L1A11_RS07280	COG1132	(ABC) transporter
L1A11_RS07290	COG4166	transmembrane transport
L1A11_RS07295	COG2244	polysaccharide biosynthetic process
L1A11_RS07300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L1A11_RS07325	COG2827	Endonuclease containing a URI domain
L1A11_RS07330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
L1A11_RS07335	COG1098	S1 RNA binding domain
L1A11_RS07345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
L1A11_RS07350	COG0629	single-stranded DNA binding
L1A11_RS07360	COG0017	Asparaginyl-tRNA synthetase
L1A11_RS07370	COG0436	Aminotransferase
L1A11_RS07400	COG0242	peptide deformylase activity
L1A11_RS07405	COG0625	glutathione transferase activity
L1A11_RS07415	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
L1A11_RS07420	COG0488	(ABC) transporter
L1A11_RS07425	COG0617	tRNA 3'-terminal CCA addition
L1A11_RS07435	COG1307	EDD domain protein, DegV family
L1A11_RS07455	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
L1A11_RS07470	COG0391	Required for morphogenesis under gluconeogenic growth conditions
L1A11_RS07480	COG0251	oxidation-reduction process
L1A11_RS07500	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L1A11_RS07520	COG3935	DnaD domain protein
L1A11_RS07535	COG2226	methyltransferase
L1A11_RS07545	COG3842	ATPase activity
L1A11_RS07555	COG1335	isochorismatase
L1A11_RS07565	COG0513	Belongs to the DEAD box helicase family
L1A11_RS07570	COG2223	nitrite transmembrane transporter activity
L1A11_RS07575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L1A11_RS07580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L1A11_RS07585	COG3442	glutamine amidotransferase
L1A11_RS07590	COG0006	proline dipeptidase activity
L1A11_RS07605	COG4720	Psort location CytoplasmicMembrane, score
L1A11_RS07610	COG0351	phosphomethylpyrimidine kinase
L1A11_RS07630	COG2824	Alkylphosphonate utilization operon protein PhnA
L1A11_RS07650	COG0463	Glycosyl transferase, family 2
L1A11_RS07655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1A11_RS07665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L1A11_RS07670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L1A11_RS07675	COG2384	SAM-dependent methyltransferase
L1A11_RS07695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L1A11_RS07700	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L1A11_RS07705	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L1A11_RS07705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1A11_RS07705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1A11_RS07710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L1A11_RS07730	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L1A11_RS07735	COG0204	Acyl-transferase
L1A11_RS07750	COG2910	NAD(P)H-binding
L1A11_RS07770	COG5002	protein histidine kinase activity
L1A11_RS07775	COG0745	RESPONSE REGULATOR receiver
L1A11_RS07790	COG1959	2 iron, 2 sulfur cluster binding
L1A11_RS07830	COG3590	peptidase
L1A11_RS07845	COG0803	Belongs to the bacterial solute-binding protein 9 family
L1A11_RS07850	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
L1A11_RS07860	COG1136	(ABC) transporter
L1A11_RS07860	COG0577	efflux transmembrane transporter activity
L1A11_RS07910	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
L1A11_RS07930	COG1051	belongs to the nudix hydrolase family
L1A11_RS07935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L1A11_RS07950	COG0768	penicillin binding
L1A11_RS07965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L1A11_RS07980	COG2731	YhcH YjgK YiaL family protein
L1A11_RS07985	COG0395	ABC-type sugar transport system, permease component
L1A11_RS07990	COG1175	transmembrane transport
L1A11_RS08000	COG1263	PTS System
L1A11_RS08000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS08000	COG2190	(PTS) system
L1A11_RS08010	COG0673	inositol 2-dehydrogenase activity
L1A11_RS08015	COG4409	exo-alpha-(2->6)-sialidase activity
L1A11_RS08025	COG1175	transmembrane transport
L1A11_RS08030	COG1653	transport
L1A11_RS08055	COG3458	cephalosporin-C deacetylase activity
L1A11_RS08060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L1A11_RS08075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L1A11_RS08080	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L1A11_RS08085	COG0653	protein targeting
L1A11_RS08095	COG1131	(ABC) transporter
L1A11_RS08125	COG0778	Nitroreductase
L1A11_RS08130	COG1484	DNA-dependent DNA replication
L1A11_RS08145	COG1725	Transcriptional regulator
L1A11_RS08150	COG1131	(ABC) transporter
L1A11_RS08160	COG1668	transmembrane transport
L1A11_RS08165	COG4152	abc transporter atp-binding protein
L1A11_RS08185	COG1940	carbohydrate kinase activity
L1A11_RS08190	COG2190	(PTS) system
L1A11_RS08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS08190	COG1263	PTS System
L1A11_RS08195	COG1621	beta-fructofuranosidase activity
L1A11_RS08200	COG1609	Transcriptional regulator
L1A11_RS08210	COG3425	synthase
L1A11_RS08235	COG2815	serine threonine protein kinase
L1A11_RS08235	COG0515	serine threonine protein kinase
L1A11_RS08240	COG0631	protein serine/threonine phosphatase activity
L1A11_RS08245	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
L1A11_RS08245	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
L1A11_RS08255	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L1A11_RS08265	COG0194	GDP metabolic process
L1A11_RS08280	COG1323	Belongs to the UPF0348 family
L1A11_RS08285	COG2226	methyltransferase
L1A11_RS08290	COG0799	negative regulation of ribosome biogenesis
L1A11_RS08300	COG1713	HD superfamily hydrolase involved in NAD metabolism
L1A11_RS08305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
L1A11_RS08310	COG1534	Rna-binding protein
L1A11_RS08315	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
L1A11_RS08330	COG0668	transmembrane transport
L1A11_RS08355	COG3118	belongs to the thioredoxin family
L1A11_RS08360	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
L1A11_RS08370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L1A11_RS08380	COG1164	Oligoendopeptidase f
L1A11_RS08385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L1A11_RS08395	COG1051	belongs to the nudix hydrolase family
L1A11_RS08430	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L1A11_RS08480	COG1621	beta-fructofuranosidase activity
L1A11_RS08485	COG1653	transport
L1A11_RS08490	COG0395	ABC-type sugar transport system, permease component
L1A11_RS08495	COG4209	transmembrane transport
L1A11_RS08505	COG3711	transcriptional antiterminator
L1A11_RS08510	COG2261	transglycosylase associated protein
L1A11_RS08530	COG3237	CsbD-like
L1A11_RS08550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L1A11_RS08560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS08565	COG1447	Phosphotransferase system cellobiose-specific component IIA
L1A11_RS08570	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS08580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS08585	COG1846	Transcriptional regulator
L1A11_RS08585	COG1940	carbohydrate kinase activity
L1A11_RS08595	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L1A11_RS08640	COG0512	Glutamine amidotransferase of anthranilate synthase
L1A11_RS08645	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
L1A11_RS08665	COG1285	pathogenesis
L1A11_RS08670	COG1178	ABC-type Fe3 transport system permease component
L1A11_RS08700	COG5434	Belongs to the glycosyl hydrolase 28 family
L1A11_RS08705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
L1A11_RS08710	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
L1A11_RS08715	COG1132	(ABC) transporter
L1A11_RS08720	COG1132	(ABC) transporter
L1A11_RS08735	COG0708	Exodeoxyribonuclease III
L1A11_RS08755	COG2233	PERMEase
L1A11_RS08780	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
L1A11_RS08785	COG1609	Transcriptional regulator
L1A11_RS08790	COG1063	alcohol dehydrogenase
L1A11_RS08795	COG0789	Transcriptional regulator
L1A11_RS08800	COG1230	cation diffusion facilitator family transporter
L1A11_RS08810	COG3201	nicotinamide mononucleotide transporter
L1A11_RS08815	COG1174	glycine betaine transport
L1A11_RS08840	COG1363	Peptidase, m42
L1A11_RS08845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L1A11_RS08850	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L1A11_RS08855	COG4605	iron ion homeostasis
L1A11_RS08860	COG4604	ABC transporter, ATP-binding protein
L1A11_RS08865	COG4607	ABC-type enterochelin transport system periplasmic component
L1A11_RS08875	COG1187	pseudouridine synthase activity
L1A11_RS08905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
L1A11_RS08920	COG0366	Alpha amylase catalytic
L1A11_RS08925	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
L1A11_RS08925	COG1263	PTS System
L1A11_RS08930	COG2188	Transcriptional regulator
L1A11_RS08940	COG4608	Belongs to the ABC transporter superfamily
L1A11_RS08945	COG0444	Belongs to the ABC transporter superfamily
L1A11_RS08950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L1A11_RS08955	COG0601	transmembrane transport
L1A11_RS08960	COG4166	transmembrane transport
L1A11_RS08970	COG0366	Alpha amylase catalytic
L1A11_RS08980	COG0395	ABC-type sugar transport system, permease component
L1A11_RS08985	COG1175	transmembrane transport
L1A11_RS08990	COG1653	transport
L1A11_RS08995	COG3345	alpha-galactosidase
L1A11_RS09000	COG2207	Transcriptional regulator
L1A11_RS09005	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
L1A11_RS09005	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
L1A11_RS09135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1A11_RS09140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1A11_RS09145	COG0564	pseudouridine synthase activity
L1A11_RS09155	COG1136	(ABC) transporter
L1A11_RS09155	COG0577	efflux transmembrane transporter activity
L1A11_RS09165	COG0157	Belongs to the NadC ModD family
L1A11_RS09180	COG1129	ABC transporter
L1A11_RS09185	COG2188	Transcriptional regulator
L1A11_RS09190	COG2723	6-phospho-beta-galactosidase activity
L1A11_RS09195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
L1A11_RS09205	COG1447	Phosphotransferase system cellobiose-specific component IIA
L1A11_RS09210	COG1012	belongs to the aldehyde dehydrogenase family
L1A11_RS09210	COG1454	alcohol dehydrogenase
L1A11_RS09220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L1A11_RS09230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L1A11_RS09250	COG3623	hexulose-6-phosphate isomerase
L1A11_RS09260	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1A11_RS09270	COG3037	sugar-specific permease SgaT UlaA
L1A11_RS09280	COG1847	R3H domain protein
L1A11_RS09285	COG0706	membrane insertase activity
L1A11_RS09330	COG4537	Required for transformation and DNA binding
L1A11_RS09335	COG1459	type II secretion system
L1A11_RS09340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L1A11_RS09350	COG1063	alcohol dehydrogenase
L1A11_RS09380	COG3759	membrane
L1A11_RS09395	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
L1A11_RS09395	COG0131	Imidazoleglycerol-phosphate dehydratase
L1A11_RS09400	COG0534	Mate efflux family protein
L1A11_RS09515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
L1A11_RS09520	COG1132	(ABC) transporter
L1A11_RS09530	COG1132	(ABC) transporter
L1A11_RS09540	COG1438	arginine binding
L1A11_RS09560	COG0745	RESPONSE REGULATOR receiver
L1A11_RS09565	COG5002	protein histidine kinase activity
L1A11_RS09570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
L1A11_RS09575	COG0573	inorganic phosphate transmembrane transporter activity
L1A11_RS09585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L1A11_RS09590	COG0704	Plays a role in the regulation of phosphate uptake
L1A11_RS09610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L1A11_RS09620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L1A11_RS09635	COG0697	spore germination
L1A11_RS09640	COG4499	WXG100 protein secretion system (Wss), protein YukC
L1A11_RS09640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L1A11_RS09650	COG2217	Heavy metal translocating P-type atpase
L1A11_RS09660	COG2226	methyltransferase
L1A11_RS09675	COG0058	SHG alpha-glucan phosphorylase activity
L1A11_RS09680	COG1640	4-alpha-glucanotransferase
L1A11_RS09685	COG2182	Extracellular solute-binding protein
L1A11_RS09690	COG1175	transmembrane transport
L1A11_RS09695	COG3833	ABC-type maltose transport systems, permease component
L1A11_RS09700	COG5521	maltodextrose utilization protein MalA
L1A11_RS09705	COG1609	Transcriptional regulator
L1A11_RS09715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
L1A11_RS09750	COG1476	TRANSCRIPTIONal
L1A11_RS09780	COG2151	metal-sulfur cluster biosynthetic enzyme
L1A11_RS09795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
L1A11_RS09800	COG3959	Transketolase, thiamine diphosphate binding domain
L1A11_RS09815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
L1A11_RS09835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
L1A11_RS09850	COG0383	alpha-mannosidase activity
L1A11_RS09860	COG3537	Alpha-1,2-mannosidase
L1A11_RS09880	COG0549	Belongs to the carbamate kinase family
L1A11_RS09885	COG1288	antiporter activity
L1A11_RS09890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
L1A11_RS09900	COG3064	Membrane
L1A11_RS09900	COG3525	Glycosyl hydrolase, family 20, catalytic domain
L1A11_RS09900	COG3583	domain protein
L1A11_RS09915	COG1454	alcohol dehydrogenase
L1A11_RS09920	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
L1A11_RS09925	COG0235	Class ii aldolase
L1A11_RS09955	COG1175	transmembrane transport
L1A11_RS09960	COG1653	transport
L1A11_RS09965	COG1070	Carbohydrate kinase
L1A11_RS09975	COG0803	Belongs to the bacterial solute-binding protein 9 family
L1A11_RS09975	COG3443	Belongs to the bacterial solute-binding protein 9 family
L1A11_RS09980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L1A11_RS09985	COG1121	(ABC) transporter
L1A11_RS09990	COG1846	Transcriptional regulator
L1A11_RS09995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
L1A11_RS10005	COG1696	Membrane protein involved in D-alanine export
L1A11_RS10025	COG3344	reverse transcriptase
L1A11_RS10040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
L1A11_RS10045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
L1A11_RS10065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L1A11_RS10075	COG1755	Isoprenylcysteine carboxyl methyltransferase
L1A11_RS10080	COG5002	protein histidine kinase activity
L1A11_RS10085	COG0745	RESPONSE REGULATOR receiver
L1A11_RS10090	COG0542	response to heat
L1A11_RS10095	COG4463	regulation of RNA biosynthetic process
L1A11_RS10100	COG1116	anion transmembrane transporter activity
L1A11_RS10105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L1A11_RS10130	COG0305	Participates in initiation and elongation during chromosome replication
L1A11_RS10150	COG1040	competence protein
L1A11_RS10155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
L1A11_RS10160	COG1739	Uncharacterized protein family UPF0029
L1A11_RS10195	COG3942	CHAP domain
L1A11_RS10205	COG1792	Involved in formation and maintenance of cell shape
L1A11_RS10210	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
L1A11_RS10215	COG1122	ATPase activity
L1A11_RS10220	COG1122	ATPase activity
L1A11_RS10225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L1A11_RS10235	COG0612	Peptidase, M16
L1A11_RS10240	COG0612	Peptidase, M16
L1A11_RS10245	COG2501	S4 domain
L1A11_RS10255	COG0516	GMP reductase activity
L1A11_RS10255	COG0517	IMP dehydrogenase activity
L1A11_RS10260	COG0180	Tryptophanyl-tRNA synthetase
L1A11_RS10265	COG0488	(ABC) transporter
L1A11_RS10275	COG1511	domain protein
L1A11_RS10285	COG1511	domain protein
L1A11_RS10330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L1A11_RS10335	COG1475	DNA binding