locus-tag	class	description
EF3030_RS00010	COG0592	DNA-directed DNA polymerase activity
EF3030_RS00020	COG0012	GTP binding
EF3030_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EF3030_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EF3030_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EF3030_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EF3030_RS00135	COG0756	dUTP diphosphatase activity
EF3030_RS00145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EF3030_RS00170	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EF3030_RS00185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EF3030_RS00185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EF3030_RS00190	COG1832	CoA-binding protein
EF3030_RS00200	COG2855	membrane
EF3030_RS00205	COG0436	Aminotransferase
EF3030_RS00220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EF3030_RS00235	COG2274	protein secretion by the type I secretion system
EF3030_RS00240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EF3030_RS00245	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EF3030_RS00255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EF3030_RS00270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EF3030_RS00285	COG0151	Belongs to the GarS family
EF3030_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EF3030_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EF3030_RS00320	COG3064	Membrane
EF3030_RS00320	COG3583	domain protein
EF3030_RS00320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EF3030_RS00335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS00340	COG3715	PTS system
EF3030_RS00345	COG3716	PTS system mannose fructose sorbose family IID component
EF3030_RS00355	COG2222	sugar isomerase
EF3030_RS00365	COG2514	catechol 2,3-dioxygenase activity
EF3030_RS00370	COG1937	Protein conserved in bacteria
EF3030_RS00400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EF3030_RS00405	COG0569	domain protein
EF3030_RS00410	COG1215	transferase activity, transferring glycosyl groups
EF3030_RS00430	COG5002	protein histidine kinase activity
EF3030_RS00460	COG4209	transmembrane transport
EF3030_RS00465	COG0395	ABC-type sugar transport system, permease component
EF3030_RS00470	COG1653	transport
EF3030_RS00500	COG1695	Transcriptional regulator
EF3030_RS00530	COG0546	phosphoglycolate phosphatase activity
EF3030_RS00535	COG1760	l-serine dehydratase
EF3030_RS00540	COG1760	l-serine dehydratase
EF3030_RS00570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS00670	COG0494	nUDIX hydrolase
EF3030_RS00675	COG0445	tRNA wobble uridine modification
EF3030_RS00710	COG1214	PFAM Peptidase M22, glycoprotease
EF3030_RS00740	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS00815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS00820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS00825	COG1464	Belongs to the NlpA lipoprotein family
EF3030_RS00830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EF3030_RS00835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EF3030_RS00855	COG2972	Histidine kinase
EF3030_RS00860	COG2207	Transcriptional regulator
EF3030_RS00860	COG4753	response regulator
EF3030_RS00870	COG1780	Probably involved in ribonucleotide reductase function
EF3030_RS00910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EF3030_RS00910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EF3030_RS00930	COG2818	Glycosylase
EF3030_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EF3030_RS00960	COG0006	proline dipeptidase activity
EF3030_RS00970	COG1393	Belongs to the ArsC family
EF3030_RS00995	COG0285	dihydrofolate synthase activity
EF3030_RS01005	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EF3030_RS01070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EF3030_RS01095	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EF3030_RS01135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EF3030_RS01150	COG0201	protein transport
EF3030_RS01160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EF3030_RS01165	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EF3030_RS01175	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EF3030_RS01180	COG0202	RNA polymerase activity
EF3030_RS01190	COG3830	Belongs to the UPF0237 family
EF3030_RS01230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EF3030_RS01235	COG1349	DNA-binding transcription factor activity
EF3030_RS01245	COG1447	Phosphotransferase system cellobiose-specific component IIA
EF3030_RS01250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS01255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS01260	COG1882	Formate acetyltransferase
EF3030_RS01305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EF3030_RS01310	COG4589	Belongs to the CDS family
EF3030_RS01315	COG0750	zinc metalloprotease
EF3030_RS01325	COG2723	6-phospho-beta-galactosidase activity
EF3030_RS01330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EF3030_RS01340	COG1523	belongs to the glycosyl hydrolase 13 family
EF3030_RS01370	COG2176	DNA-directed DNA polymerase activity
EF3030_RS01390	COG2309	aminopeptidase activity
EF3030_RS01395	COG2261	transglycosylase associated protein
EF3030_RS01405	COG1187	pseudouridine synthase activity
EF3030_RS01415	COG3579	cysteine-type endopeptidase activity
EF3030_RS01420	COG3716	PTS system mannose fructose sorbose family IID component
EF3030_RS01425	COG3715	PTS system
EF3030_RS01435	COG1064	alcohol dehydrogenase
EF3030_RS01440	COG0561	phosphatase activity
EF3030_RS01445	COG2252	PERMEase
EF3030_RS01455	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EF3030_RS01460	COG0285	dihydrofolate synthase activity
EF3030_RS01470	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EF3030_RS01470	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EF3030_RS01480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EF3030_RS01510	COG0386	Belongs to the glutathione peroxidase family
EF3030_RS01515	COG5492	domain, Protein
EF3030_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
EF3030_RS01560	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EF3030_RS01565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS01570	COG3715	PTS system
EF3030_RS01575	COG3716	PTS system mannose fructose sorbose family IID component
EF3030_RS01590	COG1609	Transcriptional regulator
EF3030_RS01620	COG4839	cell division protein FtsL
EF3030_RS01625	COG0768	penicillin binding
EF3030_RS01655	COG0366	Alpha amylase catalytic
EF3030_RS01660	COG4166	transmembrane transport
EF3030_RS01705	COG3475	LICD family
EF3030_RS01725	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EF3030_RS01730	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EF3030_RS01740	COG1088	dTDP-glucose 4,6-dehydratase activity
EF3030_RS01745	COG1091	dTDP-4-dehydrorhamnose reductase activity
EF3030_RS01755	COG4372	Transposase
EF3030_RS01760	COG4372	Transposase
EF3030_RS01770	COG4166	transmembrane transport
EF3030_RS01780	COG0366	Alpha amylase catalytic
EF3030_RS01785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EF3030_RS01810	COG0116	Belongs to the methyltransferase superfamily
EF3030_RS01820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EF3030_RS01825	COG0745	RESPONSE REGULATOR receiver
EF3030_RS01890	COG4585	Histidine kinase
EF3030_RS01895	COG2197	response regulator
EF3030_RS01935	COG2213	PTS system mannitol-specific
EF3030_RS01940	COG3711	transcriptional antiterminator
EF3030_RS01945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EF3030_RS01965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EF3030_RS01970	COG0681	Belongs to the peptidase S26 family
EF3030_RS01995	COG1115	amino acid carrier protein
EF3030_RS02020	COG0527	aspartate kinase activity
EF3030_RS02030	COG1024	Enoyl-CoA hydratase
EF3030_RS02035	COG1846	Transcriptional regulator
EF3030_RS02045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EF3030_RS02055	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EF3030_RS02060	COG1028	Short-chain dehydrogenase reductase Sdr
EF3030_RS02065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EF3030_RS02080	COG0439	Biotin carboxylase
EF3030_RS02085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EF3030_RS02145	COG1442	glycosyl transferase family 8
EF3030_RS02150	COG1442	glycosyl transferase family 8
EF3030_RS02160	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EF3030_RS02170	COG1461	Dihydroxyacetone kinase
EF3030_RS02175	COG0028	Belongs to the TPP enzyme family
EF3030_RS02180	COG0440	acetolactate synthase activity
EF3030_RS02200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EF3030_RS02220	COG0765	amino acid transport
EF3030_RS02250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EF3030_RS02260	COG1882	Formate acetyltransferase
EF3030_RS02290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EF3030_RS02295	COG0569	domain protein
EF3030_RS02310	COG1122	ATPase activity
EF3030_RS02325	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EF3030_RS02330	COG0671	phosphoesterase, PA-phosphatase related
EF3030_RS02340	COG1247	-acetyltransferase
EF3030_RS02350	COG0504	CTP synthase activity
EF3030_RS02355	COG1283	sodium-dependent phosphate transmembrane transporter activity
EF3030_RS02375	COG0789	Transcriptional regulator
EF3030_RS02380	COG0174	glutamine synthetase
EF3030_RS02400	COG4974	Belongs to the 'phage' integrase family
EF3030_RS02460	COG0484	heat shock protein binding
EF3030_RS02475	COG0537	adenosine 5'-monophosphoramidase activity
EF3030_RS02480	COG1131	(ABC) transporter
EF3030_RS02505	COG3290	protein histidine kinase activity
EF3030_RS02515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EF3030_RS02520	COG2274	protein secretion by the type I secretion system
EF3030_RS02600	COG1266	CAAX protease self-immunity
EF3030_RS02620	COG0195	Participates in both transcription termination and antitermination
EF3030_RS02625	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EF3030_RS02685	COG0519	Catalyzes the synthesis of GMP from XMP
EF3030_RS02695	COG0525	valine-tRNA ligase activity
EF3030_RS02725	COG3711	transcriptional antiterminator
EF3030_RS02730	COG2190	(PTS) system
EF3030_RS02730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS02730	COG1263	PTS System
EF3030_RS02745	COG0456	acetyltransferase
EF3030_RS02750	COG0072	phenylalanine-tRNA ligase activity
EF3030_RS02750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EF3030_RS02765	COG3620	sequence-specific DNA binding
EF3030_RS02770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EF3030_RS02790	COG1045	serine acetyltransferase
EF3030_RS02805	COG0215	cysteine-tRNA ligase activity
EF3030_RS02810	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EF3030_RS02825	COG0577	efflux transmembrane transporter activity
EF3030_RS02830	COG1136	(ABC) transporter
EF3030_RS02840	COG0745	RESPONSE REGULATOR receiver
EF3030_RS02845	COG5002	protein histidine kinase activity
EF3030_RS02850	COG0191	fructose-bisphosphate aldolase activity
EF3030_RS02855	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EF3030_RS02860	COG0765	amino acid transport
EF3030_RS02865	COG0765	amino acid transport
EF3030_RS02870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS02880	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EF3030_RS02880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EF3030_RS02920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS02935	COG1573	uracil-dna glycosylase
EF3030_RS02950	COG1114	Component of the transport system for branched-chain amino acids
EF3030_RS02955	COG1363	Peptidase, m42
EF3030_RS02995	COG4555	ABC transporter
EF3030_RS03025	COG1404	Belongs to the peptidase S8 family
EF3030_RS03040	COG3775	system Galactitol-specific IIC component
EF3030_RS03050	COG3250	beta-galactosidase activity
EF3030_RS03065	COG1242	4 iron, 4 sulfur cluster binding
EF3030_RS03070	COG1242	4 iron, 4 sulfur cluster binding
EF3030_RS03075	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EF3030_RS03095	COG0785	Cytochrome C biogenesis protein
EF3030_RS03100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EF3030_RS03105	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EF3030_RS03105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EF3030_RS03110	COG4753	response regulator
EF3030_RS03110	COG2207	Transcriptional regulator
EF3030_RS03115	COG2972	Histidine kinase
EF3030_RS03125	COG3064	Membrane
EF3030_RS03130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EF3030_RS03145	COG1940	carbohydrate kinase activity
EF3030_RS03165	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EF3030_RS03170	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EF3030_RS03180	COG0300	oxidoreductase activity
EF3030_RS03195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EF3030_RS03205	COG1187	pseudouridine synthase activity
EF3030_RS03210	COG1217	gtp-binding protein TYPA
EF3030_RS03230	COG1136	(ABC) transporter
EF3030_RS03245	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EF3030_RS03285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EF3030_RS03310	COG1131	(ABC) transporter
EF3030_RS03315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS03325	COG0765	amino acid transport
EF3030_RS03330	COG1304	FMN binding
EF3030_RS03345	COG1304	FMN binding
EF3030_RS03370	COG0352	thiamine-phosphate diphosphorylase activity
EF3030_RS03385	COG4172	Belongs to the ABC transporter superfamily
EF3030_RS03395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EF3030_RS03405	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EF3030_RS03410	COG0352	thiamine-phosphate diphosphorylase activity
EF3030_RS03430	COG2217	Heavy metal translocating P-type atpase
EF3030_RS03435	COG0028	Belongs to the TPP enzyme family
EF3030_RS03455	COG2723	6-phospho-beta-galactosidase activity
EF3030_RS03460	COG1482	cell wall glycoprotein biosynthetic process
EF3030_RS03470	COG0789	Transcriptional regulator
EF3030_RS03480	COG2081	HI0933 family
EF3030_RS03485	COG1307	EDD domain protein, DegV family
EF3030_RS03495	COG2131	deaminase
EF3030_RS03500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EF3030_RS03545	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EF3030_RS03545	COG0517	IMP dehydrogenase activity
EF3030_RS03545	COG0617	tRNA 3'-terminal CCA addition
EF3030_RS03555	COG2884	Cell division ATP-binding protein ftsE
EF3030_RS03560	COG2177	Part of the ABC transporter FtsEX involved in
EF3030_RS03565	COG1263	PTS System
EF3030_RS03565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS03565	COG2190	(PTS) system
EF3030_RS03575	COG0513	Belongs to the DEAD box helicase family
EF3030_RS03590	COG0167	dihydroorotate dehydrogenase activity
EF3030_RS03600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EF3030_RS03605	COG4470	Protein conserved in bacteria
EF3030_RS03610	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EF3030_RS03620	COG0488	(ABC) transporter
EF3030_RS03650	COG1837	Belongs to the UPF0109 family
EF3030_RS03675	COG1328	CTP reductase activity
EF3030_RS03675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EF3030_RS03695	COG1268	BioY protein
EF3030_RS03700	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EF3030_RS03705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EF3030_RS03710	COG1136	(ABC) transporter
EF3030_RS03715	COG0577	efflux transmembrane transporter activity
EF3030_RS03720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EF3030_RS03720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EF3030_RS03740	COG4989	oxidoreductase activity
EF3030_RS03750	COG1028	Short-chain dehydrogenase reductase Sdr
EF3030_RS03775	COG0745	RESPONSE REGULATOR receiver
EF3030_RS03780	COG5002	protein histidine kinase activity
EF3030_RS03805	COG0772	Belongs to the SEDS family
EF3030_RS03810	COG0693	protein deglycase activity
EF3030_RS03820	COG0187	DNA topoisomerase II activity
EF3030_RS03855	COG0494	nUDIX hydrolase
EF3030_RS03865	COG0542	response to heat
EF3030_RS03870	COG4703	Protein of unknown function (DUF1797)
EF3030_RS03875	COG0765	amino acid transport
EF3030_RS03880	COG1126	abc transporter atp-binding protein
EF3030_RS03885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EF3030_RS03895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EF3030_RS03915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EF3030_RS03975	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EF3030_RS03990	COG1744	ABC transporter substrate-binding protein PnrA-like
EF3030_RS04000	COG4603	Belongs to the binding-protein-dependent transport system permease family
EF3030_RS04005	COG1079	Belongs to the binding-protein-dependent transport system permease family
EF3030_RS04020	COG0187	DNA topoisomerase II activity
EF3030_RS04025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EF3030_RS04030	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EF3030_RS04035	COG4166	transmembrane transport
EF3030_RS04070	COG0539	negative regulation of cytoplasmic translation
EF3030_RS04080	COG1956	GAF domain-containing protein
EF3030_RS04100	COG0719	Fe-S assembly protein
EF3030_RS04105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EF3030_RS04115	COG0719	Fe-S assembly protein
EF3030_RS04160	COG1349	DNA-binding transcription factor activity
EF3030_RS04165	COG1105	Belongs to the carbohydrate kinase PfkB family
EF3030_RS04170	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EF3030_RS04170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EF3030_RS04170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EF3030_RS04175	COG0697	spore germination
EF3030_RS04175	COG1674	ftsk spoiiie
EF3030_RS04185	COG1104	cysteine desulfurase activity
EF3030_RS04245	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EF3030_RS04255	COG1438	arginine binding
EF3030_RS04275	COG0469	pyruvate kinase activity
EF3030_RS04285	COG0582	viral genome integration into host DNA
EF3030_RS04325	COG3689	TIGRFAM TIGR03943 family protein
EF3030_RS04330	COG0701	Predicted permease
EF3030_RS04345	COG2183	response to ionizing radiation
EF3030_RS04365	COG1136	(ABC) transporter
EF3030_RS04370	COG0577	efflux transmembrane transporter activity
EF3030_RS04390	COG1982	Orn Lys Arg decarboxylase major
EF3030_RS04400	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EF3030_RS04420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EF3030_RS04425	COG0561	phosphatase activity
EF3030_RS04445	COG0583	DNA-binding transcription factor activity
EF3030_RS04450	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EF3030_RS04455	COG0564	pseudouridine synthase activity
EF3030_RS04460	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EF3030_RS04475	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EF3030_RS04485	COG0470	DNA polymerase III
EF3030_RS04530	COG0528	UMP kinase activity
EF3030_RS04540	COG2996	Protein conserved in bacteria
EF3030_RS04550	COG1702	phosphate starvation-inducible protein PhoH
EF3030_RS04585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EF3030_RS04590	COG1596	polysaccharide export
EF3030_RS04590	COG1555	photosystem II stabilization
EF3030_RS04595	COG2333	competence protein COMEC
EF3030_RS04595	COG0658	competence protein
EF3030_RS04605	COG1131	(ABC) transporter
EF3030_RS04635	COG0543	2 iron, 2 sulfur cluster binding
EF3030_RS04640	COG0167	dihydroorotate dehydrogenase activity
EF3030_RS04645	COG4193	domain, Protein
EF3030_RS04645	COG5263	repeat protein
EF3030_RS04650	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EF3030_RS04660	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EF3030_RS04670	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EF3030_RS04675	COG0237	dephospho-CoA kinase activity
EF3030_RS04680	COG2814	Major facilitator Superfamily
EF3030_RS04685	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EF3030_RS04695	COG0557	exoribonuclease II activity
EF3030_RS04705	COG3615	Tellurite resistance protein tehB
EF3030_RS04705	COG0500	methyltransferase
EF3030_RS04720	COG4122	O-methyltransferase activity
EF3030_RS04750	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EF3030_RS04770	COG0494	nUDIX hydrolase
EF3030_RS04780	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EF3030_RS04790	COG2176	DNA-directed DNA polymerase activity
EF3030_RS04795	COG0584	glycerophosphoryl diester phosphodiesterase
EF3030_RS04815	COG0785	Cytochrome C biogenesis protein
EF3030_RS04820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EF3030_RS04825	COG0531	amino acid
EF3030_RS04830	COG0803	Belongs to the bacterial solute-binding protein 9 family
EF3030_RS04830	COG3443	Belongs to the bacterial solute-binding protein 9 family
EF3030_RS04880	COG1970	mechanosensitive ion channel activity
EF3030_RS04890	COG4708	membrane
EF3030_RS04905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EF3030_RS04915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EF3030_RS04920	COG1942	4-Oxalocrotonate Tautomerase
EF3030_RS04925	COG1435	thymidine kinase activity
EF3030_RS04935	COG2890	protein-(glutamine-N5) methyltransferase activity
EF3030_RS04960	COG0741	lytic transglycosylase activity
EF3030_RS04970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EF3030_RS04995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EF3030_RS05000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EF3030_RS05065	COG1597	lipid kinase activity
EF3030_RS05080	COG1396	sequence-specific DNA binding
EF3030_RS05085	COG0542	response to heat
EF3030_RS05095	COG1196	nuclear chromosome segregation
EF3030_RS05135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EF3030_RS05140	COG2832	Protein of unknown function (DUF454)
EF3030_RS05145	COG3142	Participates in the control of copper homeostasis
EF3030_RS05165	COG0473	3-isopropylmalate dehydrogenase activity
EF3030_RS05175	COG0066	3-isopropylmalate dehydratase activity
EF3030_RS05190	COG1401	restriction endodeoxyribonuclease activity
EF3030_RS05215	COG1196	nuclear chromosome segregation
EF3030_RS05220	COG0561	phosphatase activity
EF3030_RS05225	COG0561	phosphatase activity
EF3030_RS05230	COG0552	protein localization to endoplasmic reticulum
EF3030_RS05240	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EF3030_RS05245	COG1126	abc transporter atp-binding protein
EF3030_RS05250	COG0765	amino acid transport
EF3030_RS05280	COG1827	regulation of RNA biosynthetic process
EF3030_RS05290	COG4684	Psort location CytoplasmicMembrane, score
EF3030_RS05295	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EF3030_RS05310	COG1194	a g-specific adenine glycosylase
EF3030_RS05315	COG0745	RESPONSE REGULATOR receiver
EF3030_RS05320	COG5002	protein histidine kinase activity
EF3030_RS05325	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EF3030_RS05350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EF3030_RS05355	COG3764	Sortase (surface protein transpeptidase)
EF3030_RS05385	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EF3030_RS05405	COG1570	exodeoxyribonuclease VII activity
EF3030_RS05420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EF3030_RS05425	COG1438	arginine binding
EF3030_RS05430	COG0497	DNA recombination
EF3030_RS05435	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EF3030_RS05485	COG3684	Belongs to the aldolase LacD family
EF3030_RS05490	COG3711	transcriptional antiterminator
EF3030_RS05510	COG2723	6-phospho-beta-galactosidase activity
EF3030_RS05530	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EF3030_RS05535	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EF3030_RS05540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EF3030_RS05545	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EF3030_RS05575	COG1011	Hydrolase
EF3030_RS05590	COG1051	belongs to the nudix hydrolase family
EF3030_RS05595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EF3030_RS05605	COG0534	Mate efflux family protein
EF3030_RS05610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EF3030_RS05615	COG0022	dehydrogenase e1 component
EF3030_RS05620	COG0508	dehydrogenase complex catalyzes the overall conversion of
EF3030_RS05625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EF3030_RS05630	COG0095	Lipoate-protein ligase
EF3030_RS05650	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EF3030_RS05660	COG3064	Membrane
EF3030_RS05665	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EF3030_RS05665	COG3583	domain protein
EF3030_RS05735	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EF3030_RS05745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EF3030_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
EF3030_RS05760	COG1523	belongs to the glycosyl hydrolase 13 family
EF3030_RS05780	COG0488	(ABC) transporter
EF3030_RS05790	COG1307	EDD domain protein, DegV family
EF3030_RS05795	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EF3030_RS05800	COG0196	riboflavin kinase activity
EF3030_RS05840	COG0280	phosphate acetyltransferase
EF3030_RS05845	COG0564	pseudouridine synthase activity
EF3030_RS05855	COG2357	RelA SpoT domain protein
EF3030_RS05865	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EF3030_RS05870	COG1104	cysteine desulfurase activity
EF3030_RS05890	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EF3030_RS05900	COG0210	DNA helicase
EF3030_RS05915	COG0024	Methionine aminopeptidase
EF3030_RS05920	COG4109	DRTGG domain
EF3030_RS05930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EF3030_RS05960	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS05965	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS05970	COG2151	metal-sulfur cluster biosynthetic enzyme
EF3030_RS05975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EF3030_RS05980	COG0358	DNA primase activity
EF3030_RS06000	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EF3030_RS06005	COG0772	Belongs to the SEDS family
EF3030_RS06030	COG1396	sequence-specific DNA binding
EF3030_RS06080	COG0758	DNA mediated transformation
EF3030_RS06085	COG4750	Nucleotidyl transferase
EF3030_RS06100	COG1063	alcohol dehydrogenase
EF3030_RS06115	COG3475	LICD family
EF3030_RS06120	COG3475	LICD family
EF3030_RS06130	COG0505	Belongs to the CarA family
EF3030_RS06145	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EF3030_RS06160	COG0488	(ABC) transporter
EF3030_RS06170	COG1704	LemA family
EF3030_RS06185	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EF3030_RS06200	COG1078	dGTPase activity
EF3030_RS06240	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EF3030_RS06245	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EF3030_RS06250	COG0077	Prephenate dehydratase
EF3030_RS06250	COG1605	Chorismate mutase
EF3030_RS06255	COG0716	FMN binding
EF3030_RS06260	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EF3030_RS06285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EF3030_RS06310	COG0402	S-adenosylhomocysteine deaminase activity
EF3030_RS06325	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EF3030_RS06325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EF3030_RS06345	COG4862	establishment of competence for transformation
EF3030_RS06360	COG1215	transferase activity, transferring glycosyl groups
EF3030_RS06370	COG3475	LICD family
EF3030_RS06380	COG0077	Prephenate dehydratase
EF3030_RS06385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EF3030_RS06400	COG0287	Prephenate dehydrogenase
EF3030_RS06425	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EF3030_RS06440	COG1131	(ABC) transporter
EF3030_RS06480	COG3842	ATPase activity
EF3030_RS06495	COG3527	Alpha-acetolactate decarboxylase
EF3030_RS06500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EF3030_RS06505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS06510	COG0704	Plays a role in the regulation of phosphate uptake
EF3030_RS06515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EF3030_RS06520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EF3030_RS06525	COG0581	inorganic phosphate transmembrane transporter activity
EF3030_RS06530	COG0573	inorganic phosphate transmembrane transporter activity
EF3030_RS06535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EF3030_RS06540	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EF3030_RS06540	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EF3030_RS06545	COG0483	inositol monophosphate 1-phosphatase activity
EF3030_RS06555	COG1393	Belongs to the ArsC family
EF3030_RS06565	COG0647	UMP catabolic process
EF3030_RS06575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EF3030_RS06595	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EF3030_RS06630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EF3030_RS06640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EF3030_RS06675	COG0826	peptidase U32
EF3030_RS06710	COG1132	(ABC) transporter
EF3030_RS06725	COG1129	ABC transporter
EF3030_RS06775	COG2188	Transcriptional regulator
EF3030_RS06780	COG0697	spore germination
EF3030_RS06785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EF3030_RS06800	COG0561	phosphatase activity
EF3030_RS06835	COG0492	ferredoxin-NADP+ reductase activity
EF3030_RS06845	COG1126	abc transporter atp-binding protein
EF3030_RS06855	COG1393	Belongs to the ArsC family
EF3030_RS06860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EF3030_RS06875	COG1272	protein, Hemolysin III
EF3030_RS06890	COG1136	(ABC) transporter
EF3030_RS06890	COG0577	efflux transmembrane transporter activity
EF3030_RS06920	COG0431	NADPH-dependent FMN reductase
EF3030_RS06920	COG1053	succinate dehydrogenase
EF3030_RS06920	COG3976	FMN-binding domain protein
EF3030_RS06935	COG0751	glycine-tRNA ligase activity
EF3030_RS06950	COG0656	L-ascorbic acid biosynthetic process
EF3030_RS06955	COG0726	polysaccharide deacetylase
EF3030_RS06970	COG0513	Belongs to the DEAD box helicase family
EF3030_RS06985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EF3030_RS07020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EF3030_RS07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EF3030_RS07040	COG1126	abc transporter atp-binding protein
EF3030_RS07055	COG0628	permease
EF3030_RS07060	COG2706	6-phosphogluconolactonase activity
EF3030_RS07125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EF3030_RS07150	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EF3030_RS07155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EF3030_RS07160	COG0626	cystathionine gamma-synthase activity
EF3030_RS07165	COG1132	(ABC) transporter
EF3030_RS07175	COG1132	(ABC) transporter
EF3030_RS07180	COG4166	transmembrane transport
EF3030_RS07185	COG2244	polysaccharide biosynthetic process
EF3030_RS07190	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EF3030_RS07215	COG2827	Endonuclease containing a URI domain
EF3030_RS07220	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EF3030_RS07225	COG1098	S1 RNA binding domain
EF3030_RS07235	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EF3030_RS07240	COG0629	single-stranded DNA binding
EF3030_RS07255	COG0436	Aminotransferase
EF3030_RS07300	COG0242	peptide deformylase activity
EF3030_RS07305	COG0625	glutathione transferase activity
EF3030_RS07315	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EF3030_RS07320	COG0488	(ABC) transporter
EF3030_RS07335	COG1307	EDD domain protein, DegV family
EF3030_RS07355	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EF3030_RS07370	COG1481	regulation of sporulation
EF3030_RS07375	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EF3030_RS07385	COG0251	oxidation-reduction process
EF3030_RS07405	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EF3030_RS07425	COG3935	DnaD domain protein
EF3030_RS07440	COG2226	methyltransferase
EF3030_RS07445	COG3842	ATPase activity
EF3030_RS07455	COG1335	isochorismatase
EF3030_RS07470	COG0513	Belongs to the DEAD box helicase family
EF3030_RS07475	COG2223	nitrite transmembrane transporter activity
EF3030_RS07480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EF3030_RS07485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EF3030_RS07490	COG3442	glutamine amidotransferase
EF3030_RS07495	COG0006	proline dipeptidase activity
EF3030_RS07510	COG4720	Psort location CytoplasmicMembrane, score
EF3030_RS07515	COG0351	phosphomethylpyrimidine kinase
EF3030_RS07540	COG2824	Alkylphosphonate utilization operon protein PhnA
EF3030_RS07545	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EF3030_RS07570	COG0463	Glycosyl transferase, family 2
EF3030_RS07575	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EF3030_RS07580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EF3030_RS07585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EF3030_RS07590	COG2384	SAM-dependent methyltransferase
EF3030_RS07610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EF3030_RS07620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EF3030_RS07625	COG0204	Acyl-transferase
EF3030_RS07640	COG2910	NAD(P)H-binding
EF3030_RS07665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EF3030_RS07670	COG5002	protein histidine kinase activity
EF3030_RS07675	COG0745	RESPONSE REGULATOR receiver
EF3030_RS07690	COG1959	2 iron, 2 sulfur cluster binding
EF3030_RS07745	COG3590	peptidase
EF3030_RS07760	COG0803	Belongs to the bacterial solute-binding protein 9 family
EF3030_RS07765	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EF3030_RS07775	COG1136	(ABC) transporter
EF3030_RS07775	COG0577	efflux transmembrane transporter activity
EF3030_RS07820	COG3599	regulation of cell shape
EF3030_RS07840	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EF3030_RS07860	COG1051	belongs to the nudix hydrolase family
EF3030_RS07865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EF3030_RS07880	COG0768	penicillin binding
EF3030_RS07895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EF3030_RS07915	COG2731	YhcH YjgK YiaL family protein
EF3030_RS07920	COG0395	ABC-type sugar transport system, permease component
EF3030_RS07925	COG1175	transmembrane transport
EF3030_RS07935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS07935	COG1263	PTS System
EF3030_RS07935	COG2190	(PTS) system
EF3030_RS07945	COG0673	inositol 2-dehydrogenase activity
EF3030_RS07950	COG4409	exo-alpha-(2->6)-sialidase activity
EF3030_RS07960	COG1175	transmembrane transport
EF3030_RS07965	COG1653	transport
EF3030_RS07985	COG3458	cephalosporin-C deacetylase activity
EF3030_RS08000	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EF3030_RS08015	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EF3030_RS08020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EF3030_RS08025	COG0653	protein targeting
EF3030_RS08035	COG1131	(ABC) transporter
EF3030_RS08070	COG1484	DNA-dependent DNA replication
EF3030_RS08085	COG1725	Transcriptional regulator
EF3030_RS08090	COG1131	(ABC) transporter
EF3030_RS08100	COG1668	transmembrane transport
EF3030_RS08105	COG4152	abc transporter atp-binding protein
EF3030_RS08125	COG1940	carbohydrate kinase activity
EF3030_RS08130	COG2190	(PTS) system
EF3030_RS08130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS08130	COG1263	PTS System
EF3030_RS08140	COG1621	beta-fructofuranosidase activity
EF3030_RS08145	COG1609	Transcriptional regulator
EF3030_RS08155	COG3425	synthase
EF3030_RS08180	COG0515	serine threonine protein kinase
EF3030_RS08180	COG2815	serine threonine protein kinase
EF3030_RS08185	COG0631	protein serine/threonine phosphatase activity
EF3030_RS08190	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EF3030_RS08190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EF3030_RS08200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EF3030_RS08210	COG0194	GDP metabolic process
EF3030_RS08220	COG4115	mRNA cleavage
EF3030_RS08240	COG2226	methyltransferase
EF3030_RS08245	COG0799	negative regulation of ribosome biogenesis
EF3030_RS08255	COG1713	HD superfamily hydrolase involved in NAD metabolism
EF3030_RS08260	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EF3030_RS08265	COG1534	Rna-binding protein
EF3030_RS08270	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EF3030_RS08285	COG0668	transmembrane transport
EF3030_RS08295	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EF3030_RS08300	COG4129	membrane
EF3030_RS08320	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS08325	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS08330	COG0653	protein targeting
EF3030_RS08350	COG0201	protein transport
EF3030_RS08355	COG1215	transferase activity, transferring glycosyl groups
EF3030_RS08365	COG1442	glycosyl transferase family 8
EF3030_RS08370	COG1442	glycosyl transferase family 8
EF3030_RS08380	COG1442	glycosyl transferase family 8
EF3030_RS08385	COG0438	transferase activity, transferring glycosyl groups
EF3030_RS08395	COG1442	glycosyl transferase family 8
EF3030_RS08395	COG1216	Glycosyl transferase, family 2
EF3030_RS08400	COG1442	glycosyl transferase family 8
EF3030_RS08405	COG1442	glycosyl transferase family 8
EF3030_RS08405	COG1216	Glycosyl transferase, family 2
EF3030_RS08445	COG3118	belongs to the thioredoxin family
EF3030_RS08450	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EF3030_RS08460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EF3030_RS08475	COG1131	(ABC) transporter
EF3030_RS08480	COG0640	Transcriptional regulator
EF3030_RS08485	COG1164	Oligoendopeptidase f
EF3030_RS08490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EF3030_RS08560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EF3030_RS08575	COG1621	beta-fructofuranosidase activity
EF3030_RS08580	COG1653	transport
EF3030_RS08585	COG0395	ABC-type sugar transport system, permease component
EF3030_RS08590	COG4209	transmembrane transport
EF3030_RS08600	COG3711	transcriptional antiterminator
EF3030_RS08605	COG2261	transglycosylase associated protein
EF3030_RS08625	COG3237	CsbD-like
EF3030_RS08645	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EF3030_RS08655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS08660	COG1447	Phosphotransferase system cellobiose-specific component IIA
EF3030_RS08665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS08675	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS08680	COG1940	carbohydrate kinase activity
EF3030_RS08680	COG1846	Transcriptional regulator
EF3030_RS08735	COG0512	Glutamine amidotransferase of anthranilate synthase
EF3030_RS08740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EF3030_RS08760	COG1285	pathogenesis
EF3030_RS08765	COG1178	ABC-type Fe3 transport system permease component
EF3030_RS08795	COG5434	Belongs to the glycosyl hydrolase 28 family
EF3030_RS08805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EF3030_RS08810	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EF3030_RS08820	COG1132	(ABC) transporter
EF3030_RS08825	COG1132	(ABC) transporter
EF3030_RS08845	COG0708	Exodeoxyribonuclease III
EF3030_RS08865	COG2233	PERMEase
EF3030_RS08890	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EF3030_RS08895	COG1609	Transcriptional regulator
EF3030_RS08900	COG1063	alcohol dehydrogenase
EF3030_RS08905	COG0789	Transcriptional regulator
EF3030_RS08910	COG1230	cation diffusion facilitator family transporter
EF3030_RS08920	COG3201	nicotinamide mononucleotide transporter
EF3030_RS08925	COG1174	glycine betaine transport
EF3030_RS08950	COG1363	Peptidase, m42
EF3030_RS08970	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EF3030_RS08975	COG4605	iron ion homeostasis
EF3030_RS08980	COG4604	ABC transporter, ATP-binding protein
EF3030_RS08985	COG4607	ABC-type enterochelin transport system periplasmic component
EF3030_RS08995	COG1187	pseudouridine synthase activity
EF3030_RS09015	COG0517	IMP dehydrogenase activity
EF3030_RS09025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EF3030_RS09040	COG0366	Alpha amylase catalytic
EF3030_RS09050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EF3030_RS09050	COG1263	PTS System
EF3030_RS09055	COG2188	Transcriptional regulator
EF3030_RS09070	COG4608	Belongs to the ABC transporter superfamily
EF3030_RS09075	COG0444	Belongs to the ABC transporter superfamily
EF3030_RS09080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EF3030_RS09085	COG0601	transmembrane transport
EF3030_RS09090	COG4166	transmembrane transport
EF3030_RS09105	COG0366	Alpha amylase catalytic
EF3030_RS09110	COG0395	ABC-type sugar transport system, permease component
EF3030_RS09115	COG1175	transmembrane transport
EF3030_RS09120	COG1653	transport
EF3030_RS09125	COG3345	alpha-galactosidase
EF3030_RS09130	COG2207	Transcriptional regulator
EF3030_RS09135	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EF3030_RS09135	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EF3030_RS09250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EF3030_RS09255	COG3231	kanamycin kinase activity
EF3030_RS09300	COG4221	oxidoreductase activity
EF3030_RS09305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EF3030_RS09310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EF3030_RS09435	COG5263	repeat protein
EF3030_RS09435	COG5632	N-Acetylmuramoyl-L-alanine amidase
EF3030_RS09460	COG1316	TRANSCRIPTIONal
EF3030_RS09470	COG0802	atpase or kinase
EF3030_RS09500	COG1136	(ABC) transporter
EF3030_RS09525	COG1253	flavin adenine dinucleotide binding
EF3030_RS09540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EF3030_RS09550	COG3480	Lon protease (S16) C-terminal proteolytic domain
EF3030_RS09560	COG0742	ribosomal rna small subunit methyltransferase
EF3030_RS09580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EF3030_RS09585	COG1254	Belongs to the acylphosphatase family
EF3030_RS09595	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EF3030_RS09605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EF3030_RS09625	COG1564	THIamine pyrophosphokinase
EF3030_RS09635	COG1162	GTPase activity
EF3030_RS09665	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EF3030_RS09670	COG0084	hydrolase, TatD family'
EF3030_RS09690	COG0436	Aminotransferase
EF3030_RS09700	COG0589	response to stress
EF3030_RS09705	COG0561	phosphatase activity
EF3030_RS09710	COG0252	asparaginase activity
EF3030_RS09715	COG1609	Transcriptional regulator
EF3030_RS09720	COG2197	response regulator
EF3030_RS09725	COG4585	Histidine kinase
EF3030_RS09730	COG0842	Transport permease protein
EF3030_RS09735	COG1131	(ABC) transporter
EF3030_RS09835	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EF3030_RS09845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EF3030_RS09875	COG0157	Belongs to the NadC ModD family
EF3030_RS09890	COG1129	ABC transporter
EF3030_RS09895	COG2188	Transcriptional regulator
EF3030_RS09900	COG2723	6-phospho-beta-galactosidase activity
EF3030_RS09905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EF3030_RS09915	COG1447	Phosphotransferase system cellobiose-specific component IIA
EF3030_RS09920	COG1012	belongs to the aldehyde dehydrogenase family
EF3030_RS09920	COG1454	alcohol dehydrogenase
EF3030_RS09930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EF3030_RS09940	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EF3030_RS09960	COG3623	hexulose-6-phosphate isomerase
EF3030_RS09970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EF3030_RS09980	COG3037	sugar-specific permease SgaT UlaA
EF3030_RS09990	COG1847	R3H domain protein
EF3030_RS09995	COG0706	membrane insertase activity
EF3030_RS10005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EF3030_RS10040	COG4537	Required for transformation and DNA binding
EF3030_RS10045	COG1459	type II secretion system
EF3030_RS10050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EF3030_RS10060	COG1063	alcohol dehydrogenase
EF3030_RS10090	COG3759	membrane
EF3030_RS10105	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EF3030_RS10105	COG0131	Imidazoleglycerol-phosphate dehydratase
EF3030_RS10110	COG0534	Mate efflux family protein
EF3030_RS10225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EF3030_RS10230	COG1132	(ABC) transporter
EF3030_RS10240	COG1132	(ABC) transporter
EF3030_RS10250	COG1438	arginine binding
EF3030_RS10270	COG0745	RESPONSE REGULATOR receiver
EF3030_RS10275	COG5002	protein histidine kinase activity
EF3030_RS10280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EF3030_RS10285	COG0573	inorganic phosphate transmembrane transporter activity
EF3030_RS10295	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EF3030_RS10300	COG0704	Plays a role in the regulation of phosphate uptake
EF3030_RS10320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EF3030_RS10330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EF3030_RS10345	COG0697	spore germination
EF3030_RS10350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EF3030_RS10350	COG4499	WXG100 protein secretion system (Wss), protein YukC
EF3030_RS10360	COG2217	Heavy metal translocating P-type atpase
EF3030_RS10370	COG2226	methyltransferase
EF3030_RS10390	COG0058	SHG alpha-glucan phosphorylase activity
EF3030_RS10395	COG1640	4-alpha-glucanotransferase
EF3030_RS10400	COG2182	Extracellular solute-binding protein
EF3030_RS10405	COG1175	transmembrane transport
EF3030_RS10410	COG3833	ABC-type maltose transport systems, permease component
EF3030_RS10420	COG5521	maltodextrose utilization protein MalA
EF3030_RS10425	COG1609	Transcriptional regulator
EF3030_RS10435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EF3030_RS10470	COG1476	TRANSCRIPTIONal
EF3030_RS10495	COG2151	metal-sulfur cluster biosynthetic enzyme
EF3030_RS10510	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EF3030_RS10515	COG3959	Transketolase, thiamine diphosphate binding domain
EF3030_RS10530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EF3030_RS10550	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EF3030_RS10585	COG0383	alpha-mannosidase activity
EF3030_RS10595	COG3537	Alpha-1,2-mannosidase
EF3030_RS10615	COG0549	Belongs to the carbamate kinase family
EF3030_RS10620	COG1288	antiporter activity
EF3030_RS10625	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EF3030_RS10655	COG1454	alcohol dehydrogenase
EF3030_RS10665	COG0235	Class ii aldolase
EF3030_RS10695	COG1175	transmembrane transport
EF3030_RS10700	COG1653	transport
EF3030_RS10705	COG1070	Carbohydrate kinase
EF3030_RS10720	COG3443	Belongs to the bacterial solute-binding protein 9 family
EF3030_RS10720	COG0803	Belongs to the bacterial solute-binding protein 9 family
EF3030_RS10725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EF3030_RS10730	COG1121	(ABC) transporter
EF3030_RS10735	COG1846	Transcriptional regulator
EF3030_RS10740	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EF3030_RS10765	COG2211	Major facilitator Superfamily
EF3030_RS10770	COG3344	reverse transcriptase
EF3030_RS10795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EF3030_RS10800	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EF3030_RS10820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EF3030_RS10840	COG1755	Isoprenylcysteine carboxyl methyltransferase
EF3030_RS10845	COG5002	protein histidine kinase activity
EF3030_RS10850	COG0745	RESPONSE REGULATOR receiver
EF3030_RS10865	COG0542	response to heat
EF3030_RS10870	COG4463	regulation of RNA biosynthetic process
EF3030_RS10875	COG1116	anion transmembrane transporter activity
EF3030_RS10880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EF3030_RS10885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EF3030_RS10905	COG0305	Participates in initiation and elongation during chromosome replication
EF3030_RS10925	COG1040	competence protein
EF3030_RS10930	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EF3030_RS10935	COG1739	Uncharacterized protein family UPF0029
EF3030_RS10975	COG3942	CHAP domain
EF3030_RS10985	COG1792	Involved in formation and maintenance of cell shape
EF3030_RS10990	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EF3030_RS10995	COG1122	ATPase activity
EF3030_RS11000	COG1122	ATPase activity
EF3030_RS11005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EF3030_RS11015	COG0612	Peptidase, M16
EF3030_RS11020	COG0612	Peptidase, M16
EF3030_RS11025	COG2501	S4 domain
EF3030_RS11035	COG0516	GMP reductase activity
EF3030_RS11035	COG0517	IMP dehydrogenase activity
EF3030_RS11040	COG0180	Tryptophanyl-tRNA synthetase
EF3030_RS11045	COG0488	(ABC) transporter
EF3030_RS11060	COG1511	domain protein
EF3030_RS11105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EF3030_RS11110	COG1475	DNA binding