locus-tag class description SPH_RS00005 PF00308 Bacterial dnaA protein SPH_RS00005 PF08299 Bacterial dnaA protein helix-turn-helix SPH_RS00010 PF02768 DNA polymerase III beta subunit, C-terminal domain SPH_RS00010 PF02767 DNA polymerase III beta subunit, central domain SPH_RS00010 PF00712 DNA polymerase III beta subunit, N-terminal domain SPH_RS00020 PF06071 Protein of unknown function (DUF933) SPH_RS00020 PF01926 50S ribosome-binding GTPase SPH_RS00025 PF01195 Peptidyl-tRNA hydrolase SPH_RS00030 PF17757 UvrB interaction domain SPH_RS00030 PF03461 TRCF domain SPH_RS00030 PF00271 Helicase conserved C-terminal domain SPH_RS00030 PF00270 DEAD/DEAH box helicase SPH_RS00030 PF02559 CarD-like/TRCF domain SPH_RS00035 PF01479 S4 domain SPH_RS00055 PF01171 PP-loop family SPH_RS00055 PF11734 TilS substrate C-terminal domain SPH_RS00060 PF00156 Phosphoribosyl transferase domain SPH_RS00065 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS00065 PF17862 AAA+ lid domain SPH_RS00065 PF06480 FtsH Extracellular SPH_RS00065 PF01434 Peptidase family M41 SPH_RS00125 PF00709 Adenylosuccinate synthetase SPH_RS00215 PF00589 Phage integrase family SPH_RS00315 PF01473 Putative cell wall binding repeat SPH_RS00315 PF01510 N-acetylmuramoyl-L-alanine amidase SPH_RS00325 PF14437 MafB19-like deaminase SPH_RS00330 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS00330 PF00589 Phage integrase family SPH_RS00345 PF01381 Helix-turn-helix SPH_RS00355 PF10548 P22AR C-terminal domain SPH_RS00355 PF08346 AntA/AntB antirepressor SPH_RS00385 PF00436 Single-strand binding protein family SPH_RS00570 PF00692 dUTPase SPH_RS00585 PF00484 Carbonic anhydrase SPH_RS00595 PF14572 Phosphoribosyl synthetase-associated domain SPH_RS00595 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPH_RS00615 PF01367 5'-3' exonuclease, C-terminal SAM fold SPH_RS00615 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain SPH_RS00615 PF00476 DNA polymerase family A SPH_RS00620 PF13380 CoA binding domain SPH_RS00630 PF03601 Conserved hypothetical protein 698 SPH_RS00635 PF00155 Aminotransferase class I and II SPH_RS00640 PF02565 Recombination protein O C terminal SPH_RS00640 PF11967 Recombination protein O N terminal SPH_RS00645 PF02504 Fatty acid synthesis protein SPH_RS00650 PF00550 Phosphopantetheine attachment site SPH_RS00695 PF00005 ABC transporter SPH_RS00695 PF01476 LysM domain SPH_RS00710 PF00005 ABC transporter SPH_RS00710 PF03412 Peptidase C39 family SPH_RS00710 PF00664 ABC transporter transmembrane region SPH_RS00720 PF01259 SAICAR synthetase SPH_RS00725 PF01259 SAICAR synthetase SPH_RS00730 PF00586 AIR synthase related protein, N-terminal domain SPH_RS00730 PF02769 AIR synthase related protein, C-terminal domain SPH_RS00730 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain SPH_RS00735 PF00156 Phosphoribosyl transferase domain SPH_RS00740 PF02769 AIR synthase related protein, C-terminal domain SPH_RS00740 PF00586 AIR synthase related protein, N-terminal domain SPH_RS00745 PF00551 Formyl transferase SPH_RS00750 PF04892 VanZ like family SPH_RS00755 PF01808 AICARFT/IMPCHase bienzyme SPH_RS00755 PF02142 MGS-like domain SPH_RS00760 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPH_RS00760 PF02844 Phosphoribosylglycinamide synthetase, N domain SPH_RS00760 PF02843 Phosphoribosylglycinamide synthetase, C domain SPH_RS00765 PF00731 AIR carboxylase SPH_RS00770 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPH_RS00770 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain SPH_RS00770 PF02222 ATP-grasp domain SPH_RS00780 PF10397 Adenylosuccinate lyase C-terminus SPH_RS00780 PF00206 Lyase SPH_RS00785 PF00746 LPXTG cell wall anchor motif SPH_RS00785 PF00728 Glycosyl hydrolase family 20, catalytic domain SPH_RS00785 PF04650 YSIRK type signal peptide SPH_RS00785 PF07501 G5 domain SPH_RS00790 PF07702 UTRA domain SPH_RS00790 PF00392 Bacterial regulatory proteins, gntR family SPH_RS00795 PF01301 Glycosyl hydrolases family 35 SPH_RS00800 PF03830 PTS system sorbose subfamily IIB component SPH_RS00805 PF03609 PTS system sorbose-specific iic component SPH_RS00810 PF03613 PTS system mannose/fructose/sorbose family IID component SPH_RS00820 PF01380 SIS domain SPH_RS00825 PF01263 Aldose 1-epimerase SPH_RS00830 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPH_RS00835 PF02583 Metal-sensitive transcriptional repressor SPH_RS00860 PF02386 Cation transport protein SPH_RS00865 PF02254 TrkA-N domain SPH_RS00865 PF02080 TrkA-C domain SPH_RS00870 PF00535 Glycosyl transferase family 2 SPH_RS00885 PF00486 Transcriptional regulatory protein, C terminal SPH_RS00885 PF00072 Response regulator receiver domain SPH_RS00890 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS00890 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS00895 PF01479 S4 domain SPH_RS00895 PF00163 Ribosomal protein S4/S9 N-terminal domain SPH_RS00915 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS00920 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS00930 PF12010 Domain of unknown function (DUF3502) SPH_RS00935 PF12368 Rhodanase C-terminal SPH_RS00935 PF17773 UPF0176 acylphosphatase like domain SPH_RS00935 PF00581 Rhodanese-like domain SPH_RS00960 PF03551 Transcriptional regulator PadR-like family SPH_RS00960 PF10400 Virulence activator alpha C-term SPH_RS00975 PF02719 Polysaccharide biosynthesis protein SPH_RS00980 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS00985 PF03313 Serine dehydratase alpha chain SPH_RS00990 PF03315 Serine dehydratase beta chain SPH_RS00990 PF01842 ACT domain SPH_RS00995 PF01476 LysM domain SPH_RS00995 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPH_RS01000 PF01381 Helix-turn-helix SPH_RS01025 PF02687 FtsX-like permease family SPH_RS01025 PF12704 MacB-like periplasmic core domain SPH_RS01025 PF00005 ABC transporter SPH_RS01030 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS01035 PF00764 Arginosuccinate synthase SPH_RS01040 PF00206 Lyase SPH_RS01040 PF14698 Argininosuccinate lyase C-terminal SPH_RS01120 PF00293 NUDIX domain SPH_RS01125 PF01134 Glucose inhibited division protein A SPH_RS01125 PF13932 GidA associated domain SPH_RS01135 PF00753 Metallo-beta-lactamase superfamily SPH_RS01135 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPH_RS01135 PF17770 Ribonuclease J C-terminal domain SPH_RS01140 PF07288 Protein of unknown function (DUF1447) SPH_RS01160 PF00814 Glycoprotease family SPH_RS01170 PF00814 Glycoprotease family SPH_RS01175 PF01610 Transposase SPH_RS01175 PF13683 Integrase core domain SPH_RS01195 PF00534 Glycosyl transferases group 1 SPH_RS01195 PF13439 Glycosyltransferase Family 4 SPH_RS01200 PF00535 Glycosyl transferase family 2 SPH_RS01205 PF00664 ABC transporter transmembrane region SPH_RS01205 PF03412 Peptidase C39 family SPH_RS01205 PF00005 ABC transporter SPH_RS01220 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPH_RS01220 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPH_RS01225 PF01381 Helix-turn-helix SPH_RS01260 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS01265 PF03180 NLPA lipoprotein SPH_RS01270 PF07687 Peptidase dimerisation domain SPH_RS01270 PF01546 Peptidase family M20/M25/M40 SPH_RS01275 PF00005 ABC transporter SPH_RS01275 PF09383 NIL domain SPH_RS01280 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS01295 PF00672 HAMP domain SPH_RS01295 PF06580 Histidine kinase SPH_RS01295 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS01295 PF02743 Cache domain SPH_RS01300 PF00072 Response regulator receiver domain SPH_RS01300 PF12833 Helix-turn-helix domain SPH_RS01310 PF07972 NrdI Flavodoxin like SPH_RS01330 PF04397 LytTr DNA-binding domain SPH_RS01335 PF08676 MutL C terminal dimerisation domain SPH_RS01335 PF01119 DNA mismatch repair protein, C-terminal domain SPH_RS01340 PF00885 6,7-dimethyl-8-ribityllumazine synthase SPH_RS01345 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SPH_RS01345 PF00925 GTP cyclohydrolase II SPH_RS01350 PF00677 Lumazine binding domain SPH_RS01355 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS01355 PF01872 RibD C-terminal domain SPH_RS01360 PF07499 RuvA, C-terminal domain SPH_RS01360 PF01330 RuvA N terminal domain SPH_RS01365 PF13302 Acetyltransferase (GNAT) domain SPH_RS01365 PF13673 Acetyltransferase (GNAT) domain SPH_RS01365 PF00117 Glutamine amidotransferase class-I SPH_RS01365 PF00958 GMP synthase C terminal domain SPH_RS01365 PF03352 Methyladenine glycosylase SPH_RS01390 PF00589 Phage integrase family SPH_RS01390 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS01465 PF00005 ABC transporter SPH_RS01465 PF17755 UvrA DNA-binding domain SPH_RS01465 PF17760 UvrA interaction domain SPH_RS01470 PF01321 Creatinase/Prolidase N-terminal domain SPH_RS01470 PF00557 Metallopeptidase family M24 SPH_RS01475 PF03960 ArsC family SPH_RS01485 PF06135 IreB regulatory phosphoprotein SPH_RS01490 PF03652 Holliday junction resolvase SPH_RS01495 PF06949 Protein of unknown function (DUF1292) SPH_RS01500 PF02875 Mur ligase family, glutamate ligase domain SPH_RS01500 PF08245 Mur ligase middle domain SPH_RS01510 PF13091 PLD-like domain SPH_RS01525 PF03477 ATP cone domain SPH_RS01525 PF13597 Anaerobic ribonucleoside-triphosphate reductase SPH_RS01550 PF00338 Ribosomal protein S10p/S20e SPH_RS01555 PF00297 Ribosomal protein L3 SPH_RS01560 PF00573 Ribosomal protein L4/L1 family SPH_RS01565 PF00276 Ribosomal protein L23 SPH_RS01570 PF03947 Ribosomal Proteins L2, C-terminal domain SPH_RS01570 PF00181 Ribosomal Proteins L2, RNA binding domain SPH_RS01575 PF00203 Ribosomal protein S19 SPH_RS01580 PF00237 Ribosomal protein L22p/L17e SPH_RS01585 PF07650 KH domain SPH_RS01585 PF00189 Ribosomal protein S3, C-terminal domain SPH_RS01590 PF00252 Ribosomal protein L16p/L10e SPH_RS01595 PF00831 Ribosomal L29 protein SPH_RS01600 PF00366 Ribosomal protein S17 SPH_RS01605 PF00238 Ribosomal protein L14p/L23e SPH_RS01610 PF00467 KOW motif SPH_RS01610 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 SPH_RS01615 PF00673 ribosomal L5P family C-terminus SPH_RS01615 PF00281 Ribosomal protein L5 SPH_RS01620 PF00253 Ribosomal protein S14p/S29e SPH_RS01625 PF00410 Ribosomal protein S8 SPH_RS01630 PF00347 Ribosomal protein L6 SPH_RS01635 PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SPH_RS01640 PF00333 Ribosomal protein S5, N-terminal domain SPH_RS01640 PF03719 Ribosomal protein S5, C-terminal domain SPH_RS01645 PF00327 Ribosomal protein L30p/L7e SPH_RS01650 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SPH_RS01655 PF00344 SecY translocase SPH_RS01665 PF01176 Translation initiation factor 1A / IF-1 SPH_RS01670 PF00444 Ribosomal protein L36 SPH_RS01675 PF00416 Ribosomal protein S13/S18 SPH_RS01680 PF00411 Ribosomal protein S11 SPH_RS01685 PF01000 RNA polymerase Rpb3/RpoA insert domain SPH_RS01685 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain SPH_RS01685 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain SPH_RS01690 PF01196 Ribosomal protein L17 SPH_RS01700 PF05167 Uncharacterised ACR (DUF711) SPH_RS01715 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS01720 PF08402 TOBE domain SPH_RS01720 PF00005 ABC transporter SPH_RS01745 PF12833 Helix-turn-helix domain SPH_RS01745 PF00072 Response regulator receiver domain SPH_RS01755 PF04055 Radical SAM superfamily SPH_RS01760 PF08220 DeoR-like helix-turn-helix domain SPH_RS01760 PF00455 DeoR C terminal sensor domain SPH_RS01765 PF04198 Putative sugar-binding domain SPH_RS01765 PF13936 Helix-turn-helix domain SPH_RS01770 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS01775 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS01780 PF02378 Phosphotransferase system, EIIC SPH_RS01785 PF02901 Pyruvate formate lyase-like SPH_RS01785 PF01228 Glycine radical SPH_RS01790 PF00923 Transaldolase/Fructose-6-phosphate aldolase SPH_RS01795 PF00465 Iron-containing alcohol dehydrogenase SPH_RS01800 PF08264 Anticodon-binding domain of tRNA SPH_RS01800 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS01800 PF13603 Leucyl-tRNA synthetase, Domain 2 SPH_RS01800 PF09334 tRNA synthetases class I (M) SPH_RS01825 PF17864 RuvB AAA lid domain SPH_RS01825 PF05491 RuvB C-terminal winged helix domain SPH_RS01825 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPH_RS01835 PF01255 Putative undecaprenyl diphosphate synthase SPH_RS01845 PF02163 Peptidase family M50 SPH_RS01850 PF03129 Anticodon binding domain SPH_RS01850 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS01850 PF04073 Aminoacyl-tRNA editing domain SPH_RS01855 PF00232 Glycosyl hydrolase family 1 SPH_RS01860 PF01380 SIS domain SPH_RS01875 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS01875 PF03714 Bacterial pullanase-associated domain SPH_RS01875 PF00128 Alpha amylase, catalytic domain SPH_RS01880 PF00164 Ribosomal protein S12/S23 SPH_RS01885 PF00177 Ribosomal protein S7p/S5e SPH_RS01890 PF03764 Elongation factor G, domain IV SPH_RS01890 PF00679 Elongation factor G C-terminus SPH_RS01890 PF03144 Elongation factor Tu domain 2 SPH_RS01890 PF14492 Elongation Factor G, domain II SPH_RS01890 PF00009 Elongation factor Tu GTP binding domain SPH_RS01895 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPH_RS01895 PF14480 DNA polymerase III polC-type N-terminus I SPH_RS01895 PF11490 DNA polymerase III polC-type N-terminus II SPH_RS01895 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPH_RS01895 PF02811 PHP domain SPH_RS01895 PF00929 Exonuclease SPH_RS01915 PF02073 Thermophilic metalloprotease (M29) SPH_RS01925 PF00849 RNA pseudouridylate synthase SPH_RS01925 PF01479 S4 domain SPH_RS01935 PF03051 Peptidase C1-like family SPH_RS01940 PF03613 PTS system mannose/fructose/sorbose family IID component SPH_RS01945 PF03609 PTS system sorbose-specific iic component SPH_RS01950 PF03830 PTS system sorbose subfamily IIB component SPH_RS01950 PF03610 PTS system fructose IIA component SPH_RS01955 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS01955 PF00107 Zinc-binding dehydrogenase SPH_RS01965 PF00860 Permease family SPH_RS01980 PF00809 Pterin binding enzyme SPH_RS01985 PF02875 Mur ligase family, glutamate ligase domain SPH_RS01985 PF08245 Mur ligase middle domain SPH_RS01990 PF01227 GTP cyclohydrolase I SPH_RS01995 PF02152 Dihydroneopterin aldolase SPH_RS01995 PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SPH_RS02005 PF00572 Ribosomal protein L13 SPH_RS02010 PF00380 Ribosomal protein S9/S16 SPH_RS02020 PF09397 Ftsk gamma domain SPH_RS02020 PF17854 FtsK alpha domain SPH_RS02020 PF01580 FtsK/SpoIIIE family SPH_RS02045 PF13635 Domain of unknown function (DUF4143) SPH_RS02045 PF13173 AAA domain SPH_RS02055 PF01055 Glycosyl hydrolases family 31 SPH_RS02055 PF16338 Domain of unknown function (DUF4968) SPH_RS02055 PF17137 Domain of unknown function (DUF5110) SPH_RS02055 PF13802 Galactose mutarotase-like SPH_RS02060 PF00255 Glutathione peroxidase SPH_RS02065 PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain SPH_RS02065 PF02278 Polysaccharide lyase family 8, super-sandwich domain SPH_RS02065 PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain SPH_RS02070 PF01797 Transposase IS200 like SPH_RS02080 PF00294 pfkB family carbohydrate kinase SPH_RS02100 PF07470 Glycosyl Hydrolase Family 88 SPH_RS02105 PF03830 PTS system sorbose subfamily IIB component SPH_RS02110 PF03609 PTS system sorbose-specific iic component SPH_RS02115 PF03613 PTS system mannose/fructose/sorbose family IID component SPH_RS02130 PF00356 Bacterial regulatory proteins, lacI family SPH_RS02155 PF01795 MraW methylase family SPH_RS02165 PF00905 Penicillin binding protein transpeptidase domain SPH_RS02165 PF03717 Penicillin-binding Protein dimerisation domain SPH_RS02165 PF03793 PASTA domain SPH_RS02170 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SPH_RS02170 PF00953 Glycosyl transferase family 4 SPH_RS02175 PF17871 AAA lid domain SPH_RS02175 PF07724 AAA domain (Cdc48 subfamily) SPH_RS02175 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS02175 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS02180 PF02664 S-Ribosylhomocysteinase (LuxS) SPH_RS02185 PF08903 Domain of unknown function (DUF1846) SPH_RS02190 PF00128 Alpha amylase, catalytic domain SPH_RS02190 PF16657 Maltogenic Amylase, C-terminal domain SPH_RS02195 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS02220 PF02706 Chain length determinant protein SPH_RS02225 PF13614 AAA domain SPH_RS02230 PF02397 Bacterial sugar transferase SPH_RS02235 PF03808 Glycosyl transferase WecB/TagA/CpsF family SPH_RS02240 PF04991 LicD family SPH_RS02260 PF02350 UDP-N-acetylglucosamine 2-epimerase SPH_RS02265 PF00483 Nucleotidyl transferase SPH_RS02270 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SPH_RS02275 PF16363 GDP-mannose 4,6 dehydratase SPH_RS02280 PF04321 RmlD substrate binding domain SPH_RS02305 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS02310 PF00754 F5/8 type C domain SPH_RS02310 PF18080 Galactose mutarotase-like fold domain SPH_RS02310 PF17974 Galactose-binding domain-like SPH_RS02310 PF17995 Endo-alpha-N-acetylgalactosaminidase N-terminal SPH_RS02310 PF17451 Glycosyl hydrolase 101 beta sandwich domain SPH_RS02310 PF04650 YSIRK type signal peptide SPH_RS02310 PF12905 Endo-alpha-N-acetylgalactosaminidase SPH_RS02315 PF00905 Penicillin binding protein transpeptidase domain SPH_RS02315 PF00912 Transglycosylase SPH_RS02320 PF03838 Recombination protein U SPH_RS02325 PF06908 YspA SLOG family SPH_RS02330 PF05103 DivIVA protein SPH_RS02335 PF02926 THUMP domain SPH_RS02335 PF01170 Putative RNA methylase family UPF0020 SPH_RS02340 PF18041 MapZ extracellular domain 1 SPH_RS02340 PF18708 MapZ extracellular C-terminal domain 2 SPH_RS02345 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPH_RS02345 PF00393 6-phosphogluconate dehydrogenase, C-terminal domain SPH_RS02350 PF00072 Response regulator receiver domain SPH_RS02350 PF00486 Transcriptional regulatory protein, C terminal SPH_RS02375 PF00288 GHMP kinases N terminal domain SPH_RS02375 PF08544 GHMP kinases C terminal SPH_RS02375 PF10509 Galactokinase galactose-binding signature SPH_RS02385 PF00288 GHMP kinases N terminal domain SPH_RS02385 PF08544 GHMP kinases C terminal SPH_RS02390 PF01070 FMN-dependent dehydrogenase SPH_RS02400 PF07730 Histidine kinase SPH_RS02400 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS02405 PF00072 Response regulator receiver domain SPH_RS02405 PF00196 Bacterial regulatory proteins, luxR family SPH_RS02440 PF13333 Integrase core domain SPH_RS02440 PF00665 Integrase core domain SPH_RS02440 PF13276 HTH-like domain SPH_RS02455 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS02455 PF02378 Phosphotransferase system, EIIC SPH_RS02460 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS02460 PF08279 HTH domain SPH_RS02460 PF05043 Mga helix-turn-helix domain SPH_RS02465 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS02470 PF01232 Mannitol dehydrogenase Rossmann domain SPH_RS02470 PF08125 Mannitol dehydrogenase C-terminal domain SPH_RS02485 PF05697 Bacterial trigger factor protein (TF) SPH_RS02485 PF05698 Bacterial trigger factor protein (TF) C-terminus SPH_RS02485 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPH_RS02490 PF18335 ATP-dependent RecD-like DNA helicase SH3 domain SPH_RS02490 PF13538 UvrD-like helicase C-terminal domain SPH_RS02490 PF14490 Helix-hairpin-helix containing domain SPH_RS02495 PF10502 Signal peptidase, peptidase S26 SPH_RS02500 PF11858 Domain of unknown function (DUF3378) SPH_RS02500 PF01351 Ribonuclease HII SPH_RS02515 PF01713 Smr domain SPH_RS02515 PF00488 MutS domain V SPH_RS02520 PF01235 Sodium:alanine symporter family SPH_RS02535 PF02403 Seryl-tRNA synthetase N-terminal domain SPH_RS02535 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS02545 PF13840 ACT domain SPH_RS02545 PF00696 Amino acid kinase family SPH_RS02550 PF00378 Enoyl-CoA hydratase/isomerase SPH_RS02555 PF01047 MarR family SPH_RS02560 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPH_RS02560 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPH_RS02565 PF00550 Phosphopantetheine attachment site SPH_RS02570 PF03060 Nitronate monooxygenase SPH_RS02575 PF00698 Acyl transferase domain SPH_RS02585 PF00109 Beta-ketoacyl synthase, N-terminal domain SPH_RS02585 PF02801 Beta-ketoacyl synthase, C-terminal domain SPH_RS02590 PF00364 Biotin-requiring enzyme SPH_RS02595 PF07977 FabA-like domain SPH_RS02600 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPH_RS02600 PF02785 Biotin carboxylase C-terminal domain SPH_RS02600 PF00289 Biotin carboxylase, N-terminal domain SPH_RS02605 PF01039 Carboxyl transferase domain SPH_RS02610 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPH_RS02625 PF01029 NusB family SPH_RS02630 PF03780 Asp23 family, cell envelope-related function SPH_RS02635 PF09285 Elongation factor P, C-terminal SPH_RS02635 PF08207 Elongation factor P (EF-P) KOW-like domain SPH_RS02635 PF01132 Elongation factor P (EF-P) OB domain SPH_RS02640 PF02934 GatB/GatE catalytic domain SPH_RS02640 PF02637 GatB domain SPH_RS02645 PF01425 Amidase SPH_RS02650 PF02686 Glu-tRNAGln amidotransferase C subunit SPH_RS02655 PF00009 Elongation factor Tu GTP binding domain SPH_RS02655 PF16658 Class II release factor RF3, C-terminal domain SPH_RS02655 PF03144 Elongation factor Tu domain 2 SPH_RS02665 PF00830 Ribosomal L28 family SPH_RS02670 PF03780 Asp23 family, cell envelope-related function SPH_RS02675 PF13684 Dihydroxyacetone kinase family SPH_RS02675 PF02734 DAK2 domain SPH_RS02680 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPH_RS02680 PF00205 Thiamine pyrophosphate enzyme, central domain SPH_RS02680 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPH_RS02685 PF01842 ACT domain SPH_RS02685 PF10369 Small subunit of acetolactate synthase SPH_RS02690 PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain SPH_RS02690 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SPH_RS02705 PF00585 C-terminal regulatory domain of Threonine dehydratase SPH_RS02705 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS02715 PF00005 ABC transporter SPH_RS02720 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS02745 PF02673 Bacitracin resistance protein BacA SPH_RS02750 PF11798 IMS family HHH motif SPH_RS02750 PF00817 impB/mucB/samB family SPH_RS02750 PF11799 impB/mucB/samB family C-terminal domain SPH_RS02755 PF01228 Glycine radical SPH_RS02755 PF02901 Pyruvate formate lyase-like SPH_RS02760 PF01610 Transposase SPH_RS02760 PF13683 Integrase core domain SPH_RS02800 PF01610 Transposase SPH_RS02800 PF13683 Integrase core domain SPH_RS02830 PF00480 ROK family SPH_RS02835 PF02378 Phosphotransferase system, EIIC SPH_RS02845 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS02850 PF00232 Glycosyl hydrolase family 1 SPH_RS02855 PF02378 Phosphotransferase system, EIIC SPH_RS02855 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS02860 PF02386 Cation transport protein SPH_RS02865 PF02080 TrkA-C domain SPH_RS02865 PF02254 TrkA-N domain SPH_RS02875 PF07155 ECF-type riboflavin transporter, S component SPH_RS02885 PF00005 ABC transporter SPH_RS02885 PF12558 ATP-binding cassette cobalt transporter SPH_RS02895 PF00588 SpoU rRNA Methylase family SPH_RS02900 PF12822 ECF transporter, substrate-specific component SPH_RS02905 PF01569 PAP2 superfamily SPH_RS02915 PF00583 Acetyltransferase (GNAT) family SPH_RS02920 PF05066 HB1, ASXL, restriction endonuclease HTH domain SPH_RS02930 PF06418 CTP synthase N-terminus SPH_RS02930 PF00117 Glutamine amidotransferase class-I SPH_RS02935 PF02690 Na+/Pi-cotransporter SPH_RS02945 PF00162 Phosphoglycerate kinase SPH_RS02950 PF06081 Aromatic acid exporter family member 1 SPH_RS02955 PF13411 MerR HTH family regulatory protein SPH_RS02960 PF00120 Glutamine synthetase, catalytic domain SPH_RS02960 PF03951 Glutamine synthetase, beta-Grasp domain SPH_RS02970 PF01420 Type I restriction modification DNA specificity domain SPH_RS02975 PF02899 Phage integrase, N-terminal SAM-like domain SPH_RS02975 PF00589 Phage integrase family SPH_RS02985 PF01420 Type I restriction modification DNA specificity domain SPH_RS02990 PF12161 HsdM N-terminal domain SPH_RS02990 PF02384 N-6 DNA Methylase SPH_RS02995 PF08463 EcoEI R protein C-terminal SPH_RS02995 PF00271 Helicase conserved C-terminal domain SPH_RS02995 PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) SPH_RS02995 PF04851 Type III restriction enzyme, res subunit SPH_RS03010 PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding SPH_RS03010 PF01628 HrcA protein C terminal domain SPH_RS03015 PF01025 GrpE SPH_RS03020 PF00012 Hsp70 protein SPH_RS03030 PF01556 DnaJ C terminal domain SPH_RS03030 PF00226 DnaJ domain SPH_RS03030 PF00684 DnaJ central domain SPH_RS03040 PF01230 HIT domain SPH_RS03045 PF00005 ABC transporter SPH_RS03070 PF17203 Single cache domain 3 SPH_RS03070 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain SPH_RS03070 PF00989 PAS fold SPH_RS03070 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS03085 PF03412 Peptidase C39 family SPH_RS03085 PF00005 ABC transporter SPH_RS03085 PF00664 ABC transporter transmembrane region SPH_RS03140 PF02517 CPBP intramembrane metalloprotease SPH_RS03150 PF02390 Putative methyltransferase SPH_RS03155 PF02576 RimP N-terminal domain SPH_RS03155 PF17384 RimP C-terminal SH3 domain SPH_RS03160 PF00575 S1 RNA binding domain SPH_RS03160 PF08529 NusA N-terminal domain SPH_RS03160 PF13184 NusA-like KH domain SPH_RS03165 PF04296 Protein of unknown function (DUF448) SPH_RS03170 PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SPH_RS03175 PF11987 Translation-initiation factor 2 SPH_RS03175 PF04760 Translation initiation factor IF-2, N-terminal region SPH_RS03175 PF00009 Elongation factor Tu GTP binding domain SPH_RS03180 PF02033 Ribosome-binding factor A SPH_RS03230 PF00958 GMP synthase C terminal domain SPH_RS03230 PF03352 Methyladenine glycosylase SPH_RS03230 PF13302 Acetyltransferase (GNAT) domain SPH_RS03230 PF13673 Acetyltransferase (GNAT) domain SPH_RS03230 PF00117 Glutamine amidotransferase class-I SPH_RS03240 PF10458 Valyl tRNA synthetase tRNA binding arm SPH_RS03240 PF08264 Anticodon-binding domain of tRNA SPH_RS03240 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS03255 PF17841 BID domain of Bartonella effector protein (Bep) SPH_RS03255 PF02661 Fic/DOC family SPH_RS03280 PF00874 PRD domain SPH_RS03280 PF03123 CAT RNA binding domain SPH_RS03285 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS03285 PF02378 Phosphotransferase system, EIIC SPH_RS03285 PF00367 phosphotransferase system, EIIB SPH_RS03290 PF00232 Glycosyl hydrolase family 1 SPH_RS03295 PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain SPH_RS03295 PF01409 tRNA synthetases class II core domain (F) SPH_RS03300 PF00583 Acetyltransferase (GNAT) family SPH_RS03305 PF03483 B3/4 domain SPH_RS03305 PF03147 Ferredoxin-fold anticodon binding domain SPH_RS03305 PF03484 tRNA synthetase B5 domain SPH_RS03305 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain SPH_RS03305 PF01588 Putative tRNA binding domain SPH_RS03320 PF01381 Helix-turn-helix SPH_RS03325 PF01717 Cobalamin-independent synthase, Catalytic domain SPH_RS03325 PF08267 Cobalamin-independent synthase, N-terminal domain SPH_RS03330 PF02219 Methylenetetrahydrofolate reductase SPH_RS03335 PF01138 3' exoribonuclease family, domain 1 SPH_RS03335 PF03725 3' exoribonuclease family, domain 2 SPH_RS03335 PF00013 KH domain SPH_RS03335 PF00575 S1 RNA binding domain SPH_RS03335 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SPH_RS03340 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS03340 PF06426 Serine acetyltransferase, N-terminal SPH_RS03350 PF09190 DALR domain SPH_RS03350 PF01406 tRNA synthetases class I (C) catalytic domain SPH_RS03355 PF00636 Ribonuclease III domain SPH_RS03360 PF13556 PucR C-terminal helix-turn-helix domain SPH_RS03375 PF12704 MacB-like periplasmic core domain SPH_RS03375 PF02687 FtsX-like permease family SPH_RS03380 PF00005 ABC transporter SPH_RS03385 PF12704 MacB-like periplasmic core domain SPH_RS03385 PF02687 FtsX-like permease family SPH_RS03390 PF00486 Transcriptional regulatory protein, C terminal SPH_RS03390 PF00072 Response regulator receiver domain SPH_RS03395 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS03395 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS03395 PF00672 HAMP domain SPH_RS03400 PF01116 Fructose-bisphosphate aldolase class-II SPH_RS03405 PF00970 Oxidoreductase FAD-binding domain SPH_RS03405 PF00175 Oxidoreductase NAD-binding domain SPH_RS03405 PF00111 2Fe-2S iron-sulfur cluster binding domain SPH_RS03410 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03415 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03420 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03425 PF00005 ABC transporter SPH_RS03430 PF17768 RecJ OB domain SPH_RS03430 PF10141 Single-strand DNA-specific exonuclease, C terminal domain SPH_RS03430 PF01368 DHH family SPH_RS03430 PF02272 DHHA1 domain SPH_RS03435 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPH_RS03435 PF00753 Metallo-beta-lactamase superfamily SPH_RS03435 PF17770 Ribonuclease J C-terminal domain SPH_RS03440 PF00756 Putative esterase SPH_RS03460 PF08459 UvrC Helix-hairpin-helix N-terminal SPH_RS03460 PF02151 UvrB/uvrC motif SPH_RS03460 PF01541 GIY-YIG catalytic domain SPH_RS03470 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03475 PF00881 Nitroreductase family SPH_RS03480 PF01546 Peptidase family M20/M25/M40 SPH_RS03485 PF03167 Uracil DNA glycosylase superfamily SPH_RS03495 PF05525 Branched-chain amino acid transport protein SPH_RS03500 PF05343 M42 glutamyl aminopeptidase SPH_RS03515 PF03946 Ribosomal protein L11, N-terminal domain SPH_RS03515 PF00298 Ribosomal protein L11, RNA binding domain SPH_RS03520 PF00687 Ribosomal protein L1p/L10e family SPH_RS03540 PF00005 ABC transporter SPH_RS03570 PF00082 Subtilase family SPH_RS03575 PF13358 DDE superfamily endonuclease SPH_RS03585 PF13005 zinc-finger binding domain of transposase IS66 SPH_RS03585 PF03050 Transposase IS66 family SPH_RS03585 PF13817 IS66 C-terminal element SPH_RS03585 PF13007 Transposase C of IS166 homeodomain SPH_RS03600 PF03611 PTS system sugar-specific permease component SPH_RS03605 PF16355 Domain of unknown function (DUF4982) SPH_RS03605 PF02837 Glycosyl hydrolases family 2, sugar binding domain SPH_RS03605 PF18565 Glycoside hydrolase family 2 C-terminal domain 5 SPH_RS03605 PF00703 Glycosyl hydrolases family 2 SPH_RS03605 PF02836 Glycosyl hydrolases family 2, TIM barrel domain SPH_RS03625 PF04055 Radical SAM superfamily SPH_RS03625 PF16199 Radical_SAM C-terminal domain SPH_RS03630 PF16199 Radical_SAM C-terminal domain SPH_RS03630 PF04055 Radical SAM superfamily SPH_RS03635 PF06962 Putative rRNA methylase SPH_RS03655 PF02683 Cytochrome C biogenesis protein transmembrane region SPH_RS03660 PF08534 Redoxin SPH_RS03665 PF01625 Peptide methionine sulfoxide reductase SPH_RS03665 PF01641 SelR domain SPH_RS03670 PF12833 Helix-turn-helix domain SPH_RS03670 PF00072 Response regulator receiver domain SPH_RS03675 PF06580 Histidine kinase SPH_RS03675 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS03675 PF00672 HAMP domain SPH_RS03675 PF02743 Cache domain SPH_RS03680 PF04260 Protein of unknown function (DUF436) SPH_RS03685 PF00746 LPXTG cell wall anchor motif SPH_RS03685 PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region SPH_RS03685 PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region SPH_RS03685 PF07501 G5 domain SPH_RS03690 PF04715 Anthranilate synthase component I, N terminal region SPH_RS03690 PF00425 chorismate binding enzyme SPH_RS03705 PF00480 ROK family SPH_RS03710 PF00303 Thymidylate synthase SPH_RS03725 PF01926 50S ribosome-binding GTPase SPH_RS03725 PF16360 GTP-binding GTPase Middle Region SPH_RS03725 PF13167 GTP-binding GTPase N-terminal SPH_RS03730 PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain SPH_RS03730 PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain SPH_RS03735 PF00753 Metallo-beta-lactamase superfamily SPH_RS03735 PF12706 Beta-lactamase superfamily domain SPH_RS03740 PF00106 short chain dehydrogenase SPH_RS03745 PF03466 LysR substrate binding domain SPH_RS03745 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPH_RS03755 PF00581 Rhodanese-like domain SPH_RS03765 PF01479 S4 domain SPH_RS03765 PF00849 RNA pseudouridylate synthase SPH_RS03770 PF14492 Elongation Factor G, domain II SPH_RS03770 PF00679 Elongation factor G C-terminus SPH_RS03770 PF03144 Elongation factor Tu domain 2 SPH_RS03770 PF00009 Elongation factor Tu GTP binding domain SPH_RS03790 PF00005 ABC transporter SPH_RS03795 PF08245 Mur ligase middle domain SPH_RS03795 PF02875 Mur ligase family, glutamate ligase domain SPH_RS03800 PF03033 Glycosyltransferase family 28 N-terminal domain SPH_RS03800 PF04101 Glycosyltransferase family 28 C-terminal domain SPH_RS03805 PF08478 POTRA domain, FtsQ-type SPH_RS03810 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPH_RS03815 PF00156 Phosphoribosyl transferase domain SPH_RS03840 PF00005 ABC transporter SPH_RS03845 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03860 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03865 PF01070 FMN-dependent dehydrogenase SPH_RS03870 PF00152 tRNA synthetases class II (D, K and N) SPH_RS03870 PF01336 OB-fold nucleic acid binding domain SPH_RS03885 PF02110 Hydroxyethylthiazole kinase family SPH_RS03890 PF02581 Thiamine monophosphate synthase SPH_RS03900 PF00005 ABC transporter SPH_RS03910 PF03070 TENA/THI-4/PQQC family SPH_RS03920 PF02110 Hydroxyethylthiazole kinase family SPH_RS03925 PF02581 Thiamine monophosphate synthase SPH_RS03930 PF08543 Phosphomethylpyrimidine kinase SPH_RS03935 PF03965 Penicillinase repressor SPH_RS03945 PF00403 Heavy-metal-associated domain SPH_RS03950 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPH_RS03950 PF00205 Thiamine pyrophosphate enzyme, central domain SPH_RS03950 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPH_RS03965 PF13358 DDE superfamily endonuclease SPH_RS03980 PF01380 SIS domain SPH_RS03980 PF01418 Helix-turn-helix domain, rpiR family SPH_RS03985 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS03990 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03995 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS04035 PF00232 Glycosyl hydrolase family 1 SPH_RS04040 PF01238 Phosphomannose isomerase type I SPH_RS04045 PF00209 Sodium:neurotransmitter symporter family SPH_RS04070 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS04080 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS04090 PF00574 Clp protease SPH_RS04095 PF09902 Uncharacterized protein conserved in bacteria (DUF2129) SPH_RS04100 PF13458 Periplasmic binding protein SPH_RS04105 PF02653 Branched-chain amino acid transport system / permease component SPH_RS04110 PF02653 Branched-chain amino acid transport system / permease component SPH_RS04110 PF11862 Domain of unknown function (DUF3382) SPH_RS04115 PF12399 Branched-chain amino acid ATP-binding cassette transporter SPH_RS04115 PF00005 ABC transporter SPH_RS04120 PF00005 ABC transporter SPH_RS04125 PF00571 CBS domain SPH_RS04125 PF01743 Poly A polymerase head domain SPH_RS04130 PF03462 PCRF domain SPH_RS04130 PF00472 RF-1 domain SPH_RS04135 PF00005 ABC transporter SPH_RS04140 PF02687 FtsX-like permease family SPH_RS04140 PF18075 FtsX extracellular domain SPH_RS04145 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS04145 PF02378 Phosphotransferase system, EIIC SPH_RS04145 PF00367 phosphotransferase system, EIIB SPH_RS04150 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS04155 PF00270 DEAD/DEAH box helicase SPH_RS04155 PF00271 Helicase conserved C-terminal domain SPH_RS04160 PF00438 S-adenosylmethionine synthetase, N-terminal domain SPH_RS04160 PF02773 S-adenosylmethionine synthetase, C-terminal domain SPH_RS04160 PF02772 S-adenosylmethionine synthetase, central domain SPH_RS04165 PF01180 Dihydroorotate dehydrogenase SPH_RS04175 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SPH_RS04175 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SPH_RS04180 PF06265 Protein of unknown function (DUF1027) SPH_RS04185 PF04055 Radical SAM superfamily SPH_RS04195 PF00005 ABC transporter SPH_RS04195 PF12848 ABC transporter SPH_RS04200 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPH_RS04215 PF00886 Ribosomal protein S16 SPH_RS04230 PF05239 PRC-barrel domain SPH_RS04230 PF01782 RimM N-terminal domain SPH_RS04235 PF01746 tRNA (Guanine-1)-methyltransferase SPH_RS04240 PF03477 ATP cone domain SPH_RS04240 PF13597 Anaerobic ribonucleoside-triphosphate reductase SPH_RS04250 PF02229 Transcriptional Coactivator p15 (PC4) SPH_RS04260 PF02632 BioY family SPH_RS04265 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS04265 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS04270 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPH_RS04275 PF00005 ABC transporter SPH_RS04280 PF02687 FtsX-like permease family SPH_RS04280 PF12704 MacB-like periplasmic core domain SPH_RS04285 PF01588 Putative tRNA binding domain SPH_RS04285 PF09334 tRNA synthetases class I (M) SPH_RS04290 PF01610 Transposase SPH_RS04290 PF13683 Integrase core domain SPH_RS04310 PF00248 Aldo/keto reductase family SPH_RS04330 PF02896 PEP-utilising enzyme, TIM barrel domain SPH_RS04330 PF00391 PEP-utilising enzyme, mobile domain SPH_RS04330 PF05524 PEP-utilising enzyme, N-terminal SPH_RS04340 PF11838 ERAP1-like C-terminal domain SPH_RS04340 PF01433 Peptidase family M1 domain SPH_RS04345 PF00072 Response regulator receiver domain SPH_RS04345 PF00486 Transcriptional regulatory protein, C terminal SPH_RS04350 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04350 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS04370 PF14579 Helix-hairpin-helix motif SPH_RS04370 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPH_RS04370 PF02811 PHP domain SPH_RS04370 PF00929 Exonuclease SPH_RS04370 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPH_RS04370 PF11490 DNA polymerase III polC-type N-terminus II SPH_RS04375 PF01098 Cell cycle protein SPH_RS04380 PF01965 DJ-1/PfpI family SPH_RS04390 PF01751 Toprim domain SPH_RS04390 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04390 PF00986 DNA gyrase B subunit, carboxyl terminus SPH_RS04390 PF00204 DNA gyrase B SPH_RS04395 PF06160 Septation ring formation regulator, EzrA SPH_RS04405 PF13358 DDE superfamily endonuclease SPH_RS04415 PF00665 Integrase core domain SPH_RS04415 PF13333 Integrase core domain SPH_RS04435 PF00293 NUDIX domain SPH_RS04450 PF17871 AAA lid domain SPH_RS04450 PF07724 AAA domain (Cdc48 subfamily) SPH_RS04450 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS04450 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS04455 PF08796 Protein of unknown function (DUF1797) SPH_RS04460 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS04465 PF00005 ABC transporter SPH_RS04470 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPH_RS04470 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPH_RS04475 PF01256 Carbohydrate kinase SPH_RS04480 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SPH_RS04485 PF01676 Metalloenzyme superfamily SPH_RS04495 PF01048 Phosphorylase superfamily SPH_RS04510 PF17440 Thiol-activated cytolysin beta sandwich domain SPH_RS04510 PF01289 Thiol-activated cytolysin SPH_RS04515 PF01048 Phosphorylase superfamily SPH_RS04525 PF01649 Ribosomal protein S20 SPH_RS04530 PF00485 Phosphoribulokinase / Uridine kinase family SPH_RS04540 PF05175 Methyltransferase small domain SPH_RS04545 PF00591 Glycosyl transferase family, a/b domain SPH_RS04545 PF02885 Glycosyl transferase family, helical bundle domain SPH_RS04545 PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain SPH_RS04550 PF01791 DeoC/LacD family aldolase SPH_RS04555 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS04560 PF02608 ABC transporter substrate-binding protein PnrA-like SPH_RS04565 PF00005 ABC transporter SPH_RS04570 PF02653 Branched-chain amino acid transport system / permease component SPH_RS04575 PF02653 Branched-chain amino acid transport system / permease component SPH_RS04590 PF13333 Integrase core domain SPH_RS04590 PF00665 Integrase core domain SPH_RS04595 PF02660 Glycerol-3-phosphate acyltransferase SPH_RS04600 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04600 PF00986 DNA gyrase B subunit, carboxyl terminus SPH_RS04600 PF00204 DNA gyrase B SPH_RS04600 PF01751 Toprim domain SPH_RS04610 PF00521 DNA gyrase/topoisomerase IV, subunit A SPH_RS04610 PF03989 DNA gyrase C-terminal domain, beta-propeller SPH_RS04615 PF01063 Amino-transferase class IV SPH_RS04620 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS04635 PF01470 Pyroglutamyl peptidase SPH_RS04655 PF00575 S1 RNA binding domain SPH_RS04660 PF01610 Transposase SPH_RS04660 PF13683 Integrase core domain SPH_RS04675 PF13185 GAF domain SPH_RS04680 PF12169 DNA polymerase III subunits gamma and tau domain III SPH_RS04690 PF00005 ABC transporter SPH_RS04695 PF01458 Uncharacterized protein family (UPF0051) SPH_RS04700 PF00266 Aminotransferase class-V SPH_RS04705 PF01592 NifU-like N terminal domain SPH_RS04710 PF01458 Uncharacterized protein family (UPF0051) SPH_RS04720 PF07943 Penicillin-binding protein 5, C-terminal domain SPH_RS04720 PF00768 D-alanyl-D-alanine carboxypeptidase SPH_RS04725 PF01594 AI-2E family transporter SPH_RS04735 PF08220 DeoR-like helix-turn-helix domain SPH_RS04735 PF00455 DeoR C terminal sensor domain SPH_RS04740 PF00294 pfkB family carbohydrate kinase SPH_RS04745 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS04745 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS04750 PF01580 FtsK/SpoIIIE family SPH_RS04750 PF09397 Ftsk gamma domain SPH_RS04750 PF17854 FtsK alpha domain SPH_RS04760 PF00266 Aminotransferase class-V SPH_RS04765 PF02926 THUMP domain SPH_RS04765 PF02568 Thiamine biosynthesis protein (ThiI) SPH_RS04795 PF02384 N-6 DNA Methylase SPH_RS04800 PF01420 Type I restriction modification DNA specificity domain SPH_RS04815 PF02899 Phage integrase, N-terminal SAM-like domain SPH_RS04815 PF00589 Phage integrase family SPH_RS04825 PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) SPH_RS04825 PF04851 Type III restriction enzyme, res subunit SPH_RS04825 PF00271 Helicase conserved C-terminal domain SPH_RS04825 PF08463 EcoEI R protein C-terminal SPH_RS04835 PF01316 Arginine repressor, DNA binding domain SPH_RS04835 PF02863 Arginine repressor, C-terminal domain SPH_RS04840 PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SPH_RS04840 PF02129 X-Pro dipeptidyl-peptidase (S15 family) SPH_RS04840 PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal SPH_RS04845 PF01336 OB-fold nucleic acid binding domain SPH_RS04845 PF14579 Helix-hairpin-helix motif SPH_RS04845 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPH_RS04845 PF02811 PHP domain SPH_RS04845 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPH_RS04850 PF00365 Phosphofructokinase SPH_RS04855 PF00224 Pyruvate kinase, barrel domain SPH_RS04855 PF02887 Pyruvate kinase, alpha/beta domain SPH_RS04860 PF00589 Phage integrase family SPH_RS04860 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS04895 PF09323 Domain of unknown function (DUF1980) SPH_RS04900 PF03773 Predicted permease SPH_RS04910 PF17674 HHH domain SPH_RS04910 PF09371 Tex-like protein N-terminal domain SPH_RS04910 PF00575 S1 RNA binding domain SPH_RS04910 PF16921 Tex protein YqgF-like domain SPH_RS04915 PF10263 SprT-like family SPH_RS04915 PF17283 SprT-like zinc ribbon domain SPH_RS04935 PF00005 ABC transporter SPH_RS04940 PF02687 FtsX-like permease family SPH_RS04955 PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain SPH_RS04955 PF01276 Orn/Lys/Arg decarboxylase, major domain SPH_RS04970 PF17284 Spermidine synthase tetramerisation domain SPH_RS04975 PF16653 Saccharopine dehydrogenase C-terminal domain SPH_RS04975 PF03435 Saccharopine dehydrogenase NADP binding domain SPH_RS04980 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPH_RS04985 PF04371 Porphyromonas-type peptidyl-arginine deiminase SPH_RS04990 PF00795 Carbon-nitrogen hydrolase SPH_RS05015 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPH_RS05015 PF03466 LysR substrate binding domain SPH_RS05020 PF01252 Signal peptidase (SPase) II SPH_RS05025 PF01479 S4 domain SPH_RS05025 PF00849 RNA pseudouridylate synthase SPH_RS05035 PF01472 PUA domain SPH_RS05035 PF00696 Amino acid kinase family SPH_RS05040 PF00171 Aldehyde dehydrogenase family SPH_RS05045 PF14748 Pyrroline-5-carboxylate reductase dimerisation SPH_RS05045 PF03807 NADP oxidoreductase coenzyme F420-dependent SPH_RS05050 PF02223 Thymidylate kinase SPH_RS05055 PF09115 DNA polymerase III, delta subunit, C terminal SPH_RS05060 PF06156 Initiation control protein YabA SPH_RS05065 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPH_RS05070 PF01134 Glucose inhibited division protein A SPH_RS05075 PF00696 Amino acid kinase family SPH_RS05080 PF01765 Ribosome recycling factor SPH_RS05085 PF13509 S1 domain SPH_RS05085 PF17783 CvfB-like winged helix domain SPH_RS05090 PF06855 YozE SAM-like fold SPH_RS05095 PF02562 PhoH-like protein SPH_RS05100 PF13302 Acetyltransferase (GNAT) domain SPH_RS05105 PF10531 SLBB domain SPH_RS05110 PF00753 Metallo-beta-lactamase superfamily SPH_RS05110 PF13567 Domain of unknown function (DUF4131) SPH_RS05110 PF03772 Competence protein SPH_RS05120 PF00005 ABC transporter SPH_RS05130 PF05198 Translation initiation factor IF-3, N-terminal domain SPH_RS05130 PF00707 Translation initiation factor IF-3, C-terminal domain SPH_RS05135 PF01632 Ribosomal protein L35 SPH_RS05140 PF00453 Ribosomal protein L20 SPH_RS05145 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPH_RS05150 PF00970 Oxidoreductase FAD-binding domain SPH_RS05150 PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SPH_RS05150 PF00175 Oxidoreductase NAD-binding domain SPH_RS05155 PF01180 Dihydroorotate dehydrogenase SPH_RS05160 PF17890 Peptidoglycan hydrolase LytB WW-like domain SPH_RS05160 PF18342 Endo-beta-N-acetylglucosaminidase LytB WW domain SPH_RS05160 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPH_RS05160 PF01473 Putative cell wall binding repeat SPH_RS05165 PF05670 NFACT protein RNA binding domain SPH_RS05170 PF02130 Uncharacterized protein family UPF0054 SPH_RS05175 PF01219 Prokaryotic diacylglycerol kinase SPH_RS05180 PF01926 50S ribosome-binding GTPase SPH_RS05180 PF07650 KH domain SPH_RS05185 PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain SPH_RS05185 PF06827 Zinc finger found in FPG and IleRS SPH_RS05185 PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain SPH_RS05190 PF01121 Dephospho-CoA kinase SPH_RS05195 PF07690 Major Facilitator Superfamily SPH_RS05195 PF00083 Sugar (and other) transporter SPH_RS05200 PF00471 Ribosomal protein L33 SPH_RS05210 PF08206 Ribonuclease B OB domain SPH_RS05210 PF17876 Cold shock domain SPH_RS05210 PF00773 RNB domain SPH_RS05210 PF00575 S1 RNA binding domain SPH_RS05215 PF01668 SmpB protein SPH_RS05220 PF03848 Tellurite resistance protein TehB SPH_RS05220 PF09313 Domain of unknown function (DUF1971) SPH_RS05230 PF01432 Peptidase family M3 SPH_RS05230 PF08439 Oligopeptidase F SPH_RS05235 PF01596 O-methyltransferase SPH_RS05240 PF13145 PPIC-type PPIASE domain SPH_RS05245 PF00665 Integrase core domain SPH_RS05245 PF13333 Integrase core domain SPH_RS05260 PF04073 Aminoacyl-tRNA editing domain SPH_RS05275 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS05275 PF14602 Hexapeptide repeat of succinyl-transferase SPH_RS05275 PF00483 Nucleotidyl transferase SPH_RS05280 PF00293 NUDIX domain SPH_RS05290 PF01048 Phosphorylase superfamily SPH_RS05295 PF04394 Protein of unknown function, DUF536 SPH_RS05295 PF08279 HTH domain SPH_RS05300 PF00929 Exonuclease SPH_RS05300 PF14579 Helix-hairpin-helix motif SPH_RS05300 PF11490 DNA polymerase III polC-type N-terminus II SPH_RS05300 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPH_RS05300 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPH_RS05300 PF02811 PHP domain SPH_RS05305 PF03009 Glycerophosphoryl diester phosphodiesterase family SPH_RS05330 PF02683 Cytochrome C biogenesis protein transmembrane region SPH_RS05335 PF08534 Redoxin SPH_RS05340 PF13520 Amino acid permease SPH_RS05345 PF01297 Zinc-uptake complex component A periplasmic SPH_RS05345 PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment SPH_RS05380 PF01546 Peptidase family M20/M25/M40 SPH_RS05380 PF07687 Peptidase dimerisation domain SPH_RS05385 PF00762 Ferrochelatase SPH_RS05390 PF01741 Large-conductance mechanosensitive channel, MscL SPH_RS05400 PF06177 QueT transporter SPH_RS05410 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPH_RS05410 PF02774 Semialdehyde dehydrogenase, dimerisation domain SPH_RS05415 PF00701 Dihydrodipicolinate synthetase family SPH_RS05420 PF10396 GTP-binding protein TrmE N-terminus SPH_RS05420 PF01926 50S ribosome-binding GTPase SPH_RS05420 PF12631 MnmE helical domain SPH_RS05425 PF01361 Tautomerase enzyme SPH_RS05430 PF00265 Thymidine kinase SPH_RS05440 PF00472 RF-1 domain SPH_RS05440 PF03462 PCRF domain SPH_RS05445 PF05175 Methyltransferase small domain SPH_RS05460 PF00464 Serine hydroxymethyltransferase SPH_RS05480 PF05958 tRNA (Uracil-5-)-methyltransferase SPH_RS05505 PF01032 FecCD transport family SPH_RS05510 PF01032 FecCD transport family SPH_RS05515 PF00005 ABC transporter SPH_RS05535 PF00239 Resolvase, N terminal domain SPH_RS05535 PF02796 Helix-turn-helix domain of resolvase SPH_RS05560 PF00781 Diacylglycerol kinase catalytic domain SPH_RS05565 PF02903 Alpha amylase, N-terminal ig-like domain SPH_RS05565 PF00128 Alpha amylase, catalytic domain SPH_RS05580 PF00583 Acetyltransferase (GNAT) family SPH_RS05600 PF13613 Helix-turn-helix of DDE superfamily endonuclease SPH_RS05600 PF13359 DDE superfamily endonuclease SPH_RS05605 PF01098 Cell cycle protein SPH_RS05610 PF00311 Phosphoenolpyruvate carboxylase SPH_RS05625 PF09383 NIL domain SPH_RS05625 PF00005 ABC transporter SPH_RS05630 PF01807 CHC2 zinc finger SPH_RS05630 PF10410 DnaB-helicase binding domain of primase SPH_RS05630 PF08275 DNA primase catalytic core, N-terminal domain SPH_RS05635 PF04545 Sigma-70, region 4 SPH_RS05635 PF00140 Sigma-70 factor, region 1.2 SPH_RS05635 PF04542 Sigma-70 region 2 SPH_RS05635 PF04539 Sigma-70 region 3 SPH_RS05635 PF03979 Sigma-70 factor, region 1.1 SPH_RS05640 PF01883 Iron-sulfur cluster assembly protein SPH_RS05645 PF13439 Glycosyltransferase Family 4 SPH_RS05645 PF00534 Glycosyl transferases group 1 SPH_RS05650 PF13439 Glycosyltransferase Family 4 SPH_RS05650 PF00534 Glycosyl transferases group 1 SPH_RS05665 PF01018 GTP1/OBG SPH_RS05665 PF09269 Domain of unknown function (DUF1967) SPH_RS05665 PF01926 50S ribosome-binding GTPase SPH_RS05675 PF01610 Transposase SPH_RS05675 PF13683 Integrase core domain SPH_RS05685 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS05695 PF00571 CBS domain SPH_RS05695 PF03061 Thioesterase superfamily SPH_RS05695 PF07085 DRTGG domain SPH_RS05695 PF00392 Bacterial regulatory proteins, gntR family SPH_RS05700 PF00557 Metallopeptidase family M24 SPH_RS05720 PF13361 UvrD-like helicase C-terminal domain SPH_RS05720 PF00580 UvrD/REP helicase N-terminal domain SPH_RS05725 PF04002 RadC-like JAB domain SPH_RS05730 PF07722 Peptidase C26 SPH_RS05735 PF06971 Putative DNA-binding protein N-terminus SPH_RS05735 PF02629 CoA binding domain SPH_RS05750 PF00266 Aminotransferase class-V SPH_RS05755 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPH_RS05755 PF14572 Phosphoribosyl synthetase-associated domain SPH_RS05765 PF04607 Region found in RelA / SpoT proteins SPH_RS05770 PF01513 ATP-NAD kinase SPH_RS05775 PF00849 RNA pseudouridylate synthase SPH_RS05780 PF01515 Phosphate acetyl/butaryl transferase SPH_RS05785 PF01610 Transposase SPH_RS05785 PF13683 Integrase core domain SPH_RS05800 PF02575 YbaB/EbfC DNA-binding family SPH_RS05810 PF00829 Ribosomal prokaryotic L21 protein SPH_RS05820 PF01016 Ribosomal L27 protein SPH_RS05830 PF06574 FAD synthetase SPH_RS05830 PF01687 Riboflavin kinase SPH_RS05835 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPH_RS05835 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPH_RS05840 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS05845 PF00216 Bacterial DNA-binding protein SPH_RS05850 PF16326 ABC transporter C-terminal domain SPH_RS05850 PF00005 ABC transporter SPH_RS05850 PF12848 ABC transporter SPH_RS05865 PF00533 BRCA1 C Terminus (BRCT) domain SPH_RS05865 PF01653 NAD-dependent DNA ligase adenylation domain SPH_RS05865 PF03120 NAD-dependent DNA ligase OB-fold domain SPH_RS05865 PF03119 NAD-dependent DNA ligase C4 zinc finger domain SPH_RS05865 PF12826 Helix-hairpin-helix motif SPH_RS05870 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS05870 PF00128 Alpha amylase, catalytic domain SPH_RS05870 PF17999 Pullulanase N1-terminal domain SPH_RS05880 PF00171 Aldehyde dehydrogenase family SPH_RS05885 PF02806 Alpha amylase, C-terminal all-beta domain SPH_RS05885 PF00128 Alpha amylase, catalytic domain SPH_RS05885 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS05890 PF00483 Nucleotidyl transferase SPH_RS05895 PF00483 Nucleotidyl transferase SPH_RS05900 PF08323 Starch synthase catalytic domain SPH_RS05900 PF00534 Glycosyl transferases group 1 SPH_RS05915 PF02595 Glycerate kinase family SPH_RS05925 PF03952 Enolase, N-terminal domain SPH_RS05925 PF00113 Enolase, C-terminal TIM barrel domain SPH_RS05940 PF12705 PD-(D/E)XK nuclease superfamily SPH_RS05945 PF12705 PD-(D/E)XK nuclease superfamily SPH_RS05945 PF00580 UvrD/REP helicase N-terminal domain SPH_RS05945 PF13361 UvrD-like helicase C-terminal domain SPH_RS05955 PF07501 G5 domain SPH_RS05955 PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region SPH_RS05955 PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region SPH_RS05955 PF04650 YSIRK type signal peptide SPH_RS05955 PF00746 LPXTG cell wall anchor motif SPH_RS05960 PF13683 Integrase core domain SPH_RS05960 PF01610 Transposase SPH_RS05965 PF06970 Replication initiator protein A (RepA) N-terminus SPH_RS05965 PF18008 Replication initiator protein A C-terminal domain SPH_RS05970 PF00145 C-5 cytosine-specific DNA methylase SPH_RS06110 PF01381 Helix-turn-helix SPH_RS06115 PF06414 Zeta toxin SPH_RS06130 PF00302 Chloramphenicol acetyltransferase SPH_RS06135 PF01446 Replication protein SPH_RS06140 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SPH_RS06145 PF00128 Alpha amylase, catalytic domain SPH_RS06145 PF02903 Alpha amylase, N-terminal ig-like domain SPH_RS06160 PF01926 50S ribosome-binding GTPase SPH_RS06165 PF01351 Ribonuclease HII SPH_RS06170 PF00654 Voltage gated chloride channel SPH_RS06175 PF00589 Phage integrase family SPH_RS06185 PF13333 Integrase core domain SPH_RS06185 PF00665 Integrase core domain SPH_RS06190 PF01554 MatE SPH_RS06200 PF01979 Amidohydrolase family SPH_RS06205 PF00293 NUDIX domain SPH_RS06210 PF03167 Uracil DNA glycosylase superfamily SPH_RS06215 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS06225 PF00005 ABC transporter SPH_RS06225 PF00664 ABC transporter transmembrane region SPH_RS06230 PF00005 ABC transporter SPH_RS06240 PF00440 Bacterial regulatory proteins, tetR family SPH_RS06245 PF03610 PTS system fructose IIA component SPH_RS06250 PF02734 DAK2 domain SPH_RS06255 PF02733 Dak1 domain SPH_RS06260 PF00440 Bacterial regulatory proteins, tetR family SPH_RS06260 PF14278 Transcriptional regulator C-terminal region SPH_RS06265 PF02733 Dak1 domain SPH_RS06280 PF00391 PEP-utilising enzyme, mobile domain SPH_RS06280 PF05524 PEP-utilising enzyme, N-terminal SPH_RS06280 PF02896 PEP-utilising enzyme, TIM barrel domain SPH_RS06285 PF00381 PTS HPr component phosphorylation site SPH_RS06290 PF00462 Glutaredoxin SPH_RS06295 PF02867 Ribonucleotide reductase, barrel domain SPH_RS06295 PF00317 Ribonucleotide reductase, all-alpha domain SPH_RS06295 PF08343 Ribonucleotide reductase N-terminal SPH_RS06300 PF00268 Ribonucleotide reductase, small chain SPH_RS06305 PF00455 DeoR C terminal sensor domain SPH_RS06305 PF08220 DeoR-like helix-turn-helix domain SPH_RS06315 PF00232 Glycosyl hydrolase family 1 SPH_RS06320 PF02378 Phosphotransferase system, EIIC SPH_RS06320 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS06325 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS06330 PF03123 CAT RNA binding domain SPH_RS06330 PF00874 PRD domain SPH_RS06335 PF01791 DeoC/LacD family aldolase SPH_RS06340 PF00294 pfkB family carbohydrate kinase SPH_RS06345 PF02502 Ribose/Galactose Isomerase SPH_RS06350 PF02502 Ribose/Galactose Isomerase SPH_RS06355 PF01263 Aldose 1-epimerase SPH_RS06385 PF06421 GTP-binding protein LepA C-terminus SPH_RS06385 PF03144 Elongation factor Tu domain 2 SPH_RS06385 PF00009 Elongation factor Tu GTP binding domain SPH_RS06385 PF00679 Elongation factor G C-terminus SPH_RS06390 PF00149 Calcineurin-like phosphoesterase SPH_RS06395 PF13476 AAA domain SPH_RS06400 PF01316 Arginine repressor, DNA binding domain SPH_RS06400 PF02863 Arginine repressor, C-terminal domain SPH_RS06405 PF01479 S4 domain SPH_RS06405 PF01728 FtsJ-like methyltransferase SPH_RS06410 PF00348 Polyprenyl synthetase SPH_RS06415 PF02609 Exonuclease VII small subunit SPH_RS06420 PF13742 OB-fold nucleic acid binding domain SPH_RS06420 PF02601 Exonuclease VII, large subunit SPH_RS06425 PF00485 Phosphoribulokinase / Uridine kinase family SPH_RS06440 PF16198 tRNA pseudouridylate synthase B C-terminal domain SPH_RS06440 PF01509 TruB family pseudouridylate synthase (N terminal domain) SPH_RS06460 PF04203 Sortase domain SPH_RS06465 PF00521 DNA gyrase/topoisomerase IV, subunit A SPH_RS06465 PF03989 DNA gyrase C-terminal domain, beta-propeller SPH_RS06470 PF00056 lactate/malate dehydrogenase, NAD binding domain SPH_RS06470 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain SPH_RS06475 PF07885 Ion channel SPH_RS06490 PF00753 Metallo-beta-lactamase superfamily SPH_RS06495 PF13426 PAS domain SPH_RS06495 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS06495 PF00672 HAMP domain SPH_RS06495 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS06500 PF00072 Response regulator receiver domain SPH_RS06500 PF00486 Transcriptional regulatory protein, C terminal SPH_RS06505 PF14815 NUDIX domain SPH_RS06505 PF00730 HhH-GPD superfamily base excision DNA repair protein SPH_RS06510 PF01268 Formate--tetrahydrofolate ligase SPH_RS06520 PF02441 Flavoprotein SPH_RS06525 PF12822 ECF transporter, substrate-specific component SPH_RS06535 PF02829 3H domain SPH_RS06535 PF08279 HTH domain SPH_RS06555 PF12344 Ultra-violet resistance protein B SPH_RS06555 PF02151 UvrB/uvrC motif SPH_RS06555 PF17757 UvrB interaction domain SPH_RS06555 PF00271 Helicase conserved C-terminal domain SPH_RS06555 PF04851 Type III restriction enzyme, res subunit SPH_RS06570 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS06575 PF00005 ABC transporter SPH_RS06580 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain SPH_RS06580 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain SPH_RS06585 PF00448 SRP54-type protein, GTPase domain SPH_RS06585 PF02881 SRP54-type protein, helical bundle domain SPH_RS06600 PF06470 SMC proteins Flexible Hinge Domain SPH_RS06600 PF02463 RecF/RecN/SMC N terminal domain SPH_RS06605 PF14622 Ribonuclease-III-like SPH_RS06605 PF00035 Double-stranded RNA binding motif SPH_RS06615 PF00478 IMP dehydrogenase / GMP reductase domain SPH_RS06625 PF12102 Domain of unknown function (DUF3578) SPH_RS06625 PF07728 AAA domain (dynein-related subfamily) SPH_RS06640 PF00694 Aconitase C-terminal domain SPH_RS06650 PF00180 Isocitrate/isopropylmalate dehydrogenase SPH_RS06655 PF00682 HMGL-like SPH_RS06655 PF08502 LeuA allosteric (dimerisation) domain SPH_RS06665 PF03932 CutC family SPH_RS06670 PF04304 Protein of unknown function (DUF454) SPH_RS06675 PF01751 Toprim domain SPH_RS06675 PF01131 DNA topoisomerase SPH_RS06675 PF01396 Topoisomerase DNA binding C4 zinc finger SPH_RS06685 PF02481 DNA recombination-mediator protein A SPH_RS06685 PF18255 DNA processing protein A sterile alpha motif domain SPH_RS06690 PF12804 MobA-like NTP transferase domain SPH_RS06705 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS06710 PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPH_RS06720 PF04991 LicD family SPH_RS06725 PF04991 LicD family SPH_RS06730 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPH_RS06730 PF02142 MGS-like domain SPH_RS06730 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPH_RS06735 PF00117 Glutamine amidotransferase class-I SPH_RS06735 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SPH_RS06740 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPH_RS06740 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPH_RS06745 PF00156 Phosphoribosyl transferase domain SPH_RS06750 PF00633 Helix-hairpin-helix motif SPH_RS06750 PF10576 Iron-sulfur binding domain of endonuclease III SPH_RS06750 PF00730 HhH-GPD superfamily base excision DNA repair protein SPH_RS06765 PF12848 ABC transporter SPH_RS06765 PF00005 ABC transporter SPH_RS06765 PF16326 ABC transporter C-terminal domain SPH_RS06770 PF01435 Peptidase family M48 SPH_RS06775 PF04011 LemA family SPH_RS06780 PF02527 rRNA small subunit methyltransferase G SPH_RS06785 PF00589 Phage integrase family SPH_RS06785 PF02920 DNA binding domain of tn916 integrase SPH_RS06790 PF09035 Excisionase from transposon Tn916 SPH_RS06815 PF03764 Elongation factor G, domain IV SPH_RS06815 PF14492 Elongation Factor G, domain II SPH_RS06815 PF00009 Elongation factor Tu GTP binding domain SPH_RS06815 PF00679 Elongation factor G C-terminus SPH_RS06825 PF00877 NlpC/P60 family SPH_RS06860 PF00398 Ribosomal RNA adenine dimethylase SPH_RS06865 PF06308 23S rRNA methylastransferase leader peptide (ErmCL) SPH_RS06875 PF18106 Rolling Circle replication initiation protein N-terminal domain SPH_RS06875 PF02486 Replication initiation factor SPH_RS06895 PF00860 Permease family SPH_RS06900 PF02978 Signal peptide binding domain SPH_RS06900 PF02881 SRP54-type protein, helical bundle domain SPH_RS06900 PF00448 SRP54-type protein, GTPase domain SPH_RS06905 PF04297 Putative helix-turn-helix protein, YlxM / p13 like SPH_RS06915 PF01966 HD domain SPH_RS06935 PF01245 Ribosomal protein L19 SPH_RS06940 PF02537 CrcB-like protein, Camphor Resistance (CrcB) SPH_RS06945 PF02537 CrcB-like protein, Camphor Resistance (CrcB) SPH_RS06950 PF00800 Prephenate dehydratase SPH_RS06950 PF01817 Chorismate mutase type II SPH_RS06950 PF01842 ACT domain SPH_RS06955 PF00258 Flavodoxin SPH_RS06960 PF02272 DHHA1 domain SPH_RS06960 PF01368 DHH family SPH_RS06965 PF01197 Ribosomal protein L31 SPH_RS06985 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPH_RS06985 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPH_RS07025 PF01527 Transposase SPH_RS07030 PF00665 Integrase core domain SPH_RS07030 PF13333 Integrase core domain SPH_RS07045 PF01813 ATP synthase subunit D SPH_RS07050 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07050 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07055 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07055 PF16886 ATPsynthase alpha/beta subunit N-term extension SPH_RS07055 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07060 PF01990 ATP synthase (F/14-kDa) subunit SPH_RS07075 PF00137 ATP synthase subunit C SPH_RS07080 PF01496 V-type ATPase 116kDa subunit family SPH_RS07090 PF00480 ROK family SPH_RS07095 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPH_RS07095 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS07100 PF13088 BNR repeat-like domain SPH_RS07100 PF02973 Sialidase, N-terminal domain SPH_RS07100 PF02012 BNR/Asp-box repeat SPH_RS07110 PF00474 Sodium:solute symporter family SPH_RS07115 PF00701 Dihydrodipicolinate synthetase family SPH_RS07120 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS07125 PF01380 SIS domain SPH_RS07125 PF01418 Helix-turn-helix domain, rpiR family SPH_RS07150 PF12704 MacB-like periplasmic core domain SPH_RS07150 PF00005 ABC transporter SPH_RS07150 PF02687 FtsX-like permease family SPH_RS07155 PF00005 ABC transporter SPH_RS07155 PF00664 ABC transporter transmembrane region SPH_RS07160 PF00069 Protein kinase domain SPH_RS07170 PF01610 Transposase SPH_RS07170 PF13683 Integrase core domain SPH_RS07175 PF16320 Ribosomal protein L7/L12 dimerisation domain SPH_RS07175 PF00542 Ribosomal protein L7/L12 C-terminal domain SPH_RS07180 PF00466 Ribosomal protein L10 SPH_RS07185 PF01979 Amidohydrolase family SPH_RS07190 PF00005 ABC transporter SPH_RS07190 PF00664 ABC transporter transmembrane region SPH_RS07195 PF00005 ABC transporter SPH_RS07195 PF00664 ABC transporter transmembrane region SPH_RS07200 PF01641 SelR domain SPH_RS07200 PF01625 Peptide methionine sulfoxide reductase SPH_RS07210 PF08544 GHMP kinases C terminal SPH_RS07210 PF00288 GHMP kinases N terminal domain SPH_RS07215 PF03447 Homoserine dehydrogenase, NAD binding domain SPH_RS07215 PF00742 Homoserine dehydrogenase SPH_RS07220 PF05389 Negative regulator of genetic competence (MecA) SPH_RS07235 PF00535 Glycosyl transferase family 2 SPH_RS07240 PF00534 Glycosyl transferases group 1 SPH_RS07240 PF13439 Glycosyltransferase Family 4 SPH_RS07245 PF04991 LicD family SPH_RS07250 PF03816 Cell envelope-related transcriptional attenuator domain SPH_RS07255 PF00800 Prephenate dehydratase SPH_RS07260 PF01202 Shikimate kinase SPH_RS07265 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS07270 PF06133 Control of competence regulator ComK, YlbF/YmcA SPH_RS07275 PF02153 Prephenate dehydrogenase SPH_RS07280 PF01264 Chorismate synthase SPH_RS07285 PF01761 3-dehydroquinate synthase SPH_RS07290 PF08501 Shikimate dehydrogenase substrate binding domain SPH_RS07290 PF18317 Shikimate 5'-dehydrogenase C-terminal domain SPH_RS07295 PF01487 Type I 3-dehydroquinase SPH_RS07300 PF10672 S-adenosylmethionine-dependent methyltransferase SPH_RS07300 PF17785 PUA-like domain SPH_RS07310 PF00005 ABC transporter SPH_RS07315 PF00128 Alpha amylase, catalytic domain SPH_RS07315 PF09154 Domain of unknown function (DUF1939) SPH_RS07320 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPH_RS07320 PF02272 DHHA1 domain SPH_RS07320 PF01411 tRNA synthetases class II (A) SPH_RS07335 PF13416 Bacterial extracellular solute-binding protein SPH_RS07340 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07350 PF00005 ABC transporter SPH_RS07350 PF08402 TOBE domain SPH_RS07355 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SPH_RS07355 PF01565 FAD binding domain SPH_RS07365 PF03306 Alpha-acetolactate decarboxylase SPH_RS07370 PF00155 Aminotransferase class I and II SPH_RS07370 PF00392 Bacterial regulatory proteins, gntR family SPH_RS07375 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS07380 PF01895 PhoU domain SPH_RS07385 PF00005 ABC transporter SPH_RS07390 PF00005 ABC transporter SPH_RS07395 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07400 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07405 PF12849 PBP superfamily domain SPH_RS07410 PF01189 16S rRNA methyltransferase RsmB/F SPH_RS07410 PF13636 RNA-binding PUA-like domain of methyltransferase RsmF SPH_RS07410 PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF SPH_RS07415 PF00459 Inositol monophosphatase family SPH_RS07420 PF05256 Uncharacterised protein family (UPF0223) SPH_RS07425 PF03960 ArsC family SPH_RS07435 PF13344 Haloacid dehalogenase-like hydrolase SPH_RS07445 PF06969 HemN C-terminal domain SPH_RS07445 PF04055 Radical SAM superfamily SPH_RS07460 PF01790 Prolipoprotein diacylglyceryl transferase SPH_RS07465 PF02603 HPr Serine kinase N terminus SPH_RS07465 PF07475 HPr Serine kinase C-terminal domain SPH_RS07470 PF01165 Ribosomal protein S21 SPH_RS07475 PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SPH_RS07480 PF02547 Queuosine biosynthesis protein SPH_RS07500 PF02540 NAD synthase SPH_RS07505 PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family SPH_RS07505 PF17956 Nicotinate phosphoribosyltransferase C-terminal domain SPH_RS07505 PF17767 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SPH_RS07515 PF01381 Helix-turn-helix SPH_RS07525 PF00005 ABC transporter SPH_RS07530 PF01136 Peptidase family U32 SPH_RS07530 PF16325 Peptidase family U32 C-terminal domain SPH_RS07540 PF01136 Peptidase family U32 SPH_RS07540 PF16325 Peptidase family U32 C-terminal domain SPH_RS07555 PF18755 Restriction Enzyme Adenine Methylase Associated SPH_RS07555 PF01555 DNA methylase SPH_RS07560 PF02540 NAD synthase SPH_RS07560 PF00958 GMP synthase C terminal domain SPH_RS07560 PF00117 Glutamine amidotransferase class-I SPH_RS07565 PF07702 UTRA domain SPH_RS07565 PF00392 Bacterial regulatory proteins, gntR family SPH_RS07570 PF00892 EamA-like transporter family SPH_RS07575 PF00144 Beta-lactamase SPH_RS07600 PF09587 Bacterial capsule synthesis protein PGA_cap SPH_RS07615 PF01327 Polypeptide deformylase SPH_RS07620 PF00588 SpoU rRNA Methylase family SPH_RS07620 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPH_RS07625 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS07635 PF00005 ABC transporter SPH_RS07640 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07645 PF03960 ArsC family SPH_RS07650 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain SPH_RS07650 PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain SPH_RS07665 PF03006 Haemolysin-III related SPH_RS07670 PF01174 SNO glutamine amidotransferase family SPH_RS07675 PF01680 SOR/SNZ family SPH_RS07680 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS07680 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS07685 PF02424 ApbE family SPH_RS07690 PF03358 NADPH-dependent FMN reductase SPH_RS07690 PF04205 FMN-binding domain SPH_RS07690 PF00890 FAD binding domain SPH_RS07695 PF04205 FMN-binding domain SPH_RS07695 PF00890 FAD binding domain SPH_RS07695 PF03358 NADPH-dependent FMN reductase SPH_RS07700 PF05979 Bacterial protein of unknown function (DUF896) SPH_RS07705 PF02092 Glycyl-tRNA synthetase beta subunit SPH_RS07710 PF02091 Glycyl-tRNA synthetase alpha subunit SPH_RS07720 PF00248 Aldo/keto reductase family SPH_RS07725 PF01522 Polysaccharide deacetylase SPH_RS07725 PF18627 Peptidoglycan GlcNAc deacetylase N-terminal domain SPH_RS07735 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS07735 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPH_RS07740 PF00270 DEAD/DEAH box helicase SPH_RS07740 PF00271 Helicase conserved C-terminal domain SPH_RS07745 PF13358 DDE superfamily endonuclease SPH_RS07755 PF03144 Elongation factor Tu domain 2 SPH_RS07755 PF00009 Elongation factor Tu GTP binding domain SPH_RS07755 PF03143 Elongation factor Tu C-terminal domain SPH_RS07765 PF00230 Major intrinsic protein SPH_RS07805 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPH_RS07805 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPH_RS07805 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPH_RS07805 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPH_RS07815 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS07820 PF00005 ABC transporter SPH_RS07825 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07835 PF01594 AI-2E family transporter SPH_RS07840 PF10282 Lactonase, 7-bladed beta-propeller SPH_RS07845 PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SPH_RS07845 PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SPH_RS07850 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07850 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07855 PF00231 ATP synthase SPH_RS07860 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07860 PF00306 ATP synthase alpha/beta chain, C terminal domain SPH_RS07860 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07865 PF00213 ATP synthase delta (OSCP) subunit SPH_RS07870 PF00430 ATP synthase B/B' CF(0) SPH_RS07875 PF00119 ATP synthase A chain SPH_RS07880 PF00137 ATP synthase subunit C SPH_RS07890 PF00583 Acetyltransferase (GNAT) family SPH_RS07895 PF03449 Transcription elongation factor, N-terminal SPH_RS07895 PF01272 Transcription elongation factor, GreA/GreB, C-term SPH_RS07900 PF02618 YceG-like family SPH_RS07915 PF01225 Mur ligase family, catalytic domain SPH_RS07915 PF08245 Mur ligase middle domain SPH_RS07915 PF02875 Mur ligase family, glutamate ligase domain SPH_RS07925 PF00176 SNF2 family N-terminal domain SPH_RS07925 PF00271 Helicase conserved C-terminal domain SPH_RS07925 PF12419 SNF2 Helicase protein SPH_RS07930 PF00155 Aminotransferase class I and II SPH_RS07935 PF01053 Cys/Met metabolism PLP-dependent enzyme SPH_RS07940 PF00005 ABC transporter SPH_RS07940 PF00664 ABC transporter transmembrane region SPH_RS07945 PF00005 ABC transporter SPH_RS07945 PF00664 ABC transporter transmembrane region SPH_RS07950 PF00005 ABC transporter SPH_RS07950 PF00664 ABC transporter transmembrane region SPH_RS07955 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS07960 PF01943 Polysaccharide biosynthesis protein SPH_RS07960 PF14667 Polysaccharide biosynthesis C-terminal domain SPH_RS07965 PF02875 Mur ligase family, glutamate ligase domain SPH_RS07965 PF08245 Mur ligase middle domain SPH_RS07970 PF05532 CsbD-like SPH_RS07990 PF01368 DHH family SPH_RS07990 PF02833 DHHA2 domain SPH_RS07995 PF01541 GIY-YIG catalytic domain SPH_RS08000 PF05175 Methyltransferase small domain SPH_RS08005 PF00575 S1 RNA binding domain SPH_RS08010 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPH_RS08015 PF01084 Ribosomal protein S18 SPH_RS08020 PF00436 Single-strand binding protein family SPH_RS08025 PF01250 Ribosomal protein S6 SPH_RS08030 PF01336 OB-fold nucleic acid binding domain SPH_RS08030 PF00152 tRNA synthetases class II (D, K and N) SPH_RS08040 PF00155 Aminotransferase class I and II SPH_RS08055 PF03358 NADPH-dependent FMN reductase SPH_RS08060 PF03883 Peroxide stress protein YaaA SPH_RS08075 PF01327 Polypeptide deformylase SPH_RS08080 PF02798 Glutathione S-transferase, N-terminal domain SPH_RS08085 PF00690 Cation transporter/ATPase, N-terminus SPH_RS08085 PF00689 Cation transporting ATPase, C-terminus SPH_RS08090 PF16916 Dimerisation domain of Zinc Transporter SPH_RS08090 PF01545 Cation efflux family SPH_RS08095 PF16326 ABC transporter C-terminal domain SPH_RS08095 PF00005 ABC transporter SPH_RS08095 PF12848 ABC transporter SPH_RS08100 PF13735 tRNA nucleotidyltransferase domain 2 putative SPH_RS08100 PF01743 Poly A polymerase head domain SPH_RS08100 PF12627 Probable RNA and SrmB- binding site of polymerase A SPH_RS08105 PF01113 Dihydrodipicolinate reductase, N-terminus SPH_RS08105 PF05173 Dihydrodipicolinate reductase, C-terminus SPH_RS08110 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS08120 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPH_RS08120 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPH_RS08120 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPH_RS08120 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPH_RS08130 PF02457 DisA bacterial checkpoint controller nucleotide-binding SPH_RS08140 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS08145 PF10298 WhiA N-terminal LAGLIDADG-like domain SPH_RS08145 PF14527 WhiA LAGLIDADG-like domain SPH_RS08145 PF02650 WhiA C-terminal HTH domain SPH_RS08150 PF01933 Uncharacterised protein family UPF0052 SPH_RS08155 PF03668 P-loop ATPase protein family SPH_RS08160 PF01042 Endoribonuclease L-PSP SPH_RS08165 PF01926 50S ribosome-binding GTPase SPH_RS08170 PF06689 ClpX C4-type zinc finger SPH_RS08170 PF07724 AAA domain (Cdc48 subfamily) SPH_RS08170 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS08180 PF00186 Dihydrofolate reductase SPH_RS08185 PF00210 Ferritin-like domain SPH_RS08190 PF01473 Putative cell wall binding repeat SPH_RS08190 PF17890 Peptidoglycan hydrolase LytB WW-like domain SPH_RS08190 PF18342 Endo-beta-N-acetylglucosaminidase LytB WW domain SPH_RS08190 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPH_RS08195 PF00121 Triosephosphate isomerase SPH_RS08200 PF07261 Replication initiation and membrane attachment SPH_RS08205 PF04204 Homoserine O-succinyltransferase SPH_RS08210 PF00156 Phosphoribosyl transferase domain SPH_RS08215 PF13649 Methyltransferase domain SPH_RS08225 PF00005 ABC transporter SPH_RS08225 PF03459 TOBE domain SPH_RS08225 PF17912 MalK OB fold domain SPH_RS08235 PF00857 Isochorismatase family SPH_RS08240 PF08222 CodY helix-turn-helix domain SPH_RS08240 PF06018 CodY GAF-like domain SPH_RS08245 PF00271 Helicase conserved C-terminal domain SPH_RS08245 PF00270 DEAD/DEAH box helicase SPH_RS08250 PF07690 Major Facilitator Superfamily SPH_RS08255 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS08255 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS08260 PF08245 Mur ligase middle domain SPH_RS08260 PF08353 Domain of unknown function (DUF1727) SPH_RS08265 PF07685 CobB/CobQ-like glutamine amidotransferase domain SPH_RS08270 PF01321 Creatinase/Prolidase N-terminal domain SPH_RS08270 PF00557 Metallopeptidase family M24 SPH_RS08275 PF13333 Integrase core domain SPH_RS08275 PF00665 Integrase core domain SPH_RS08275 PF13276 HTH-like domain SPH_RS08280 PF13276 HTH-like domain SPH_RS08280 PF00665 Integrase core domain SPH_RS08280 PF13333 Integrase core domain SPH_RS08295 PF07155 ECF-type riboflavin transporter, S component SPH_RS08300 PF08543 Phosphomethylpyrimidine kinase SPH_RS08305 PF01416 tRNA pseudouridine synthase SPH_RS08325 PF03831 PhnA domain SPH_RS08325 PF08274 PhnA Zinc-Ribbon SPH_RS08330 PF02224 Cytidylate kinase SPH_RS08345 PF00535 Glycosyl transferase family 2 SPH_RS08350 PF16363 GDP-mannose 4,6 dehydratase SPH_RS08360 PF01266 FAD dependent oxidoreductase SPH_RS08365 PF01784 NIF3 (NGG1p interacting factor 3) SPH_RS08370 PF04816 tRNA (adenine(22)-N(1))-methyltransferase SPH_RS08385 PF13333 Integrase core domain SPH_RS08385 PF00665 Integrase core domain SPH_RS08385 PF13276 HTH-like domain SPH_RS08400 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS08400 PF02780 Transketolase, C-terminal domain SPH_RS08400 PF02779 Transketolase, pyrimidine binding domain SPH_RS08405 PF00834 Ribulose-phosphate 3 epimerase family SPH_RS08410 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS08410 PF02378 Phosphotransferase system, EIIC SPH_RS08415 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS08440 PF01553 Acyltransferase SPH_RS08450 PF00312 Ribosomal protein S15 SPH_RS08455 PF13460 NAD(P)H-binding SPH_RS08470 PF02824 TGS domain SPH_RS08470 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS08470 PF03129 Anticodon binding domain SPH_RS08470 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPH_RS08475 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS08480 PF00072 Response regulator receiver domain SPH_RS08480 PF00486 Transcriptional regulatory protein, C terminal SPH_RS08495 PF02082 Transcriptional regulator SPH_RS08520 PF02580 D-Tyr-tRNA(Tyr) deacylase SPH_RS08525 PF02824 TGS domain SPH_RS08525 PF13291 ACT domain SPH_RS08525 PF04607 Region found in RelA / SpoT proteins SPH_RS08540 PF00753 Metallo-beta-lactamase superfamily SPH_RS08545 PF05649 Peptidase family M13 SPH_RS08545 PF01431 Peptidase family M13 SPH_RS08550 PF00005 ABC transporter SPH_RS08555 PF00950 ABC 3 transport family SPH_RS08560 PF01297 Zinc-uptake complex component A periplasmic SPH_RS08565 PF08534 Redoxin SPH_RS08575 PF02687 FtsX-like permease family SPH_RS08575 PF12704 MacB-like periplasmic core domain SPH_RS08575 PF00005 ABC transporter SPH_RS08585 PF00300 Histidine phosphatase superfamily (branch 1) SPH_RS08600 PF06827 Zinc finger found in FPG and IleRS SPH_RS08600 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS08600 PF08264 Anticodon-binding domain of tRNA SPH_RS08615 PF05103 DivIVA protein SPH_RS08630 PF04472 Cell division protein SepF SPH_RS08635 PF01168 Alanine racemase, N-terminal domain SPH_RS08640 PF00091 Tubulin/FtsZ family, GTPase domain SPH_RS08640 PF12327 FtsZ family, C-terminal domain SPH_RS08645 PF11983 Membrane-attachment and polymerisation-promoting switch SPH_RS08645 PF02491 SHS2 domain inserted in FTSA SPH_RS08655 PF00293 NUDIX domain SPH_RS08660 PF02875 Mur ligase family, glutamate ligase domain SPH_RS08660 PF08245 Mur ligase middle domain SPH_RS08660 PF01225 Mur ligase family, catalytic domain SPH_RS08665 PF01820 D-ala D-ala ligase N-terminus SPH_RS08665 PF07478 D-ala D-ala ligase C-terminus SPH_RS08670 PF02132 RecR protein SPH_RS08670 PF13662 Toprim domain SPH_RS08675 PF03717 Penicillin-binding Protein dimerisation domain SPH_RS08675 PF00905 Penicillin binding protein transpeptidase domain SPH_RS08685 PF00480 ROK family SPH_RS08690 PF00701 Dihydrodipicolinate synthetase family SPH_RS08710 PF04074 YhcH/YjgK/YiaL SPH_RS08715 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08720 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08730 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS08735 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS08735 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPH_RS08740 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08745 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08750 PF01547 Bacterial extracellular solute-binding protein SPH_RS08760 PF02973 Sialidase, N-terminal domain SPH_RS08760 PF13088 BNR repeat-like domain SPH_RS08760 PF04650 YSIRK type signal peptide SPH_RS08775 PF05448 Acetyl xylan esterase (AXE1) SPH_RS08780 PF00270 DEAD/DEAH box helicase SPH_RS08780 PF17191 RecG wedge domain SPH_RS08780 PF00271 Helicase conserved C-terminal domain SPH_RS08785 PF01168 Alanine racemase, N-terminal domain SPH_RS08785 PF00842 Alanine racemase, C-terminal domain SPH_RS08790 PF01648 4'-phosphopantetheinyl transferase superfamily SPH_RS08795 PF00793 DAHP synthetase I family SPH_RS08800 PF00793 DAHP synthetase I family SPH_RS08805 PF07517 SecA DEAD-like domain SPH_RS08805 PF02810 SEC-C motif SPH_RS08805 PF07516 SecA Wing and Scaffold domain SPH_RS08805 PF01043 SecA preprotein cross-linking domain SPH_RS08815 PF00005 ABC transporter SPH_RS08850 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPH_RS08850 PF01926 50S ribosome-binding GTPase SPH_RS08855 PF00881 Nitroreductase family SPH_RS08860 PF07319 Primosomal protein DnaI N-terminus SPH_RS08860 PF01695 IstB-like ATP binding protein SPH_RS08870 PF03477 ATP cone domain SPH_RS08875 PF00392 Bacterial regulatory proteins, gntR family SPH_RS08880 PF00005 ABC transporter SPH_RS08895 PF00005 ABC transporter SPH_RS08895 PF13732 Domain of unknown function (DUF4162) SPH_RS08915 PF00480 ROK family SPH_RS08920 PF02378 Phosphotransferase system, EIIC SPH_RS08920 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS08920 PF00367 phosphotransferase system, EIIB SPH_RS08930 PF00251 Glycosyl hydrolases family 32 N-terminal domain SPH_RS08930 PF08244 Glycosyl hydrolases family 32 C terminal SPH_RS08940 PF00368 Hydroxymethylglutaryl-coenzyme A reductase SPH_RS08945 PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal SPH_RS08945 PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal SPH_RS08975 PF03793 PASTA domain SPH_RS08975 PF00069 Protein kinase domain SPH_RS08985 PF01029 NusB family SPH_RS08985 PF01189 16S rRNA methyltransferase RsmB/F SPH_RS08990 PF00551 Formyl transferase SPH_RS08990 PF02911 Formyl transferase, C-terminal domain SPH_RS08995 PF00271 Helicase conserved C-terminal domain SPH_RS08995 PF17764 3′ DNA-binding domain (3′BD) SPH_RS08995 PF18074 Primosomal protein N C-terminal domain SPH_RS08995 PF18319 PriA DNA helicase Cys-rich region (CRR) domain SPH_RS08995 PF04851 Type III restriction enzyme, res subunit SPH_RS09000 PF01192 RNA polymerase Rpb6 SPH_RS09005 PF00625 Guanylate kinase SPH_RS09010 PF01966 HD domain SPH_RS09010 PF12072 Domain of unknown function (DUF3552) SPH_RS09010 PF00013 KH domain SPH_RS09015 PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system SPH_RS09025 PF05636 HIGH Nucleotidyl Transferase SPH_RS09030 PF13649 Methyltransferase domain SPH_RS09045 PF01966 HD domain SPH_RS09050 PF01467 Cytidylyltransferase-like SPH_RS09055 PF01985 CRS1 / YhbY (CRM) domain SPH_RS09060 PF01926 50S ribosome-binding GTPase SPH_RS09075 PF00924 Mechanosensitive ion channel SPH_RS09085 PF11728 Putative aromatic acid exporter C-terminal domain SPH_RS09085 PF06081 Aromatic acid exporter family member 1 SPH_RS09100 PF16996 Accessory secretory protein Sec Asp4 SPH_RS09110 PF00534 Glycosyl transferases group 1 SPH_RS09115 PF07516 SecA Wing and Scaffold domain SPH_RS09115 PF01043 SecA preprotein cross-linking domain SPH_RS09115 PF07517 SecA DEAD-like domain SPH_RS09125 PF16929 Accessory Sec system GspB-transporter SPH_RS09130 PF16993 Accessory Sec system protein Asp1 SPH_RS09135 PF00344 SecY translocase SPH_RS09140 PF00535 Glycosyl transferase family 2 SPH_RS09145 PF01501 Glycosyl transferase family 8 SPH_RS09150 PF01501 Glycosyl transferase family 8 SPH_RS09155 PF01501 Glycosyl transferase family 8 SPH_RS09155 PF00535 Glycosyl transferase family 2 SPH_RS09160 PF01501 Glycosyl transferase family 8 SPH_RS09160 PF08759 Glycosyltransferase GT-D fold SPH_RS09175 PF00535 Glycosyl transferase family 2 SPH_RS09175 PF01501 Glycosyl transferase family 8 SPH_RS09180 PF01501 Glycosyl transferase family 8 SPH_RS09185 PF01501 Glycosyl transferase family 8 SPH_RS09185 PF00535 Glycosyl transferase family 2 SPH_RS09220 PF00085 Thioredoxin SPH_RS09225 PF06508 Queuosine biosynthesis protein QueC SPH_RS09225 PF14489 QueF-like protein SPH_RS09235 PF00230 Major intrinsic protein SPH_RS09250 PF08439 Oligopeptidase F SPH_RS09250 PF01432 Peptidase family M3 SPH_RS09255 PF04452 RNA methyltransferase SPH_RS09265 PF00293 NUDIX domain SPH_RS09300 PF16193 AAA C-terminal domain SPH_RS09300 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPH_RS09300 PF12002 MgsA AAA+ ATPase C terminal SPH_RS09310 PF00251 Glycosyl hydrolases family 32 N-terminal domain SPH_RS09310 PF08244 Glycosyl hydrolases family 32 C terminal SPH_RS09315 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09320 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09330 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09335 PF08280 M protein trans-acting positive regulator (MGA) HTH domain SPH_RS09335 PF05043 Mga helix-turn-helix domain SPH_RS09335 PF08270 M protein trans-acting positive regulator (MGA) PRD domain SPH_RS09355 PF03780 Asp23 family, cell envelope-related function SPH_RS09360 PF05532 CsbD-like SPH_RS09380 PF03781 Sulfatase-modifying factor enzyme 1 SPH_RS09385 PF16347 Domain of unknown function (DUF4976) SPH_RS09385 PF00884 Sulfatase SPH_RS09390 PF02378 Phosphotransferase system, EIIC SPH_RS09395 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS09400 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS09410 PF02378 Phosphotransferase system, EIIC SPH_RS09415 PF00480 ROK family SPH_RS09430 PF00290 Tryptophan synthase alpha chain SPH_RS09435 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS09440 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SPH_RS09445 PF00218 Indole-3-glycerol phosphate synthase SPH_RS09450 PF00591 Glycosyl transferase family, a/b domain SPH_RS09450 PF02885 Glycosyl transferase family, helical bundle domain SPH_RS09455 PF00117 Glutamine amidotransferase class-I SPH_RS09460 PF04715 Anthranilate synthase component I, N terminal region SPH_RS09460 PF00425 chorismate binding enzyme SPH_RS09475 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09485 PF02308 MgtC family SPH_RS09490 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09495 PF00005 ABC transporter SPH_RS09495 PF08402 TOBE domain SPH_RS09515 PF12708 Pectate lyase superfamily protein SPH_RS09515 PF04650 YSIRK type signal peptide SPH_RS09515 PF13229 Right handed beta helix region SPH_RS09530 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPH_RS09535 PF02397 Bacterial sugar transferase SPH_RS09540 PF00005 ABC transporter SPH_RS09540 PF00664 ABC transporter transmembrane region SPH_RS09545 PF00664 ABC transporter transmembrane region SPH_RS09545 PF00005 ABC transporter SPH_RS09565 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS09580 PF00156 Phosphoribosyl transferase domain SPH_RS09585 PF00860 Permease family SPH_RS09590 PF04556 DpnII restriction endonuclease SPH_RS09595 PF01555 DNA methylase SPH_RS09600 PF02086 D12 class N6 adenine-specific DNA methyltransferase SPH_RS09610 PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain SPH_RS09610 PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain SPH_RS09615 PF00288 GHMP kinases N terminal domain SPH_RS09615 PF10509 Galactokinase galactose-binding signature SPH_RS09615 PF08544 GHMP kinases C terminal SPH_RS09620 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09625 PF00107 Zinc-binding dehydrogenase SPH_RS09625 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS09630 PF13411 MerR HTH family regulatory protein SPH_RS09635 PF01545 Cation efflux family SPH_RS09645 PF04973 Nicotinamide mononucleotide transporter SPH_RS09650 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09655 PF00005 ABC transporter SPH_RS09655 PF00571 CBS domain SPH_RS09675 PF05343 M42 glutamyl aminopeptidase SPH_RS09680 PF01370 NAD dependent epimerase/dehydratase family SPH_RS09690 PF01032 FecCD transport family SPH_RS09695 PF01032 FecCD transport family SPH_RS09700 PF00005 ABC transporter SPH_RS09705 PF01497 Periplasmic binding protein SPH_RS09710 PF01809 Putative membrane protein insertion efficiency factor SPH_RS09715 PF00849 RNA pseudouridylate synthase SPH_RS09715 PF01479 S4 domain SPH_RS09720 PF04079 Segregation and condensation complex subunit ScpB SPH_RS09725 PF02616 Segregation and condensation protein ScpA SPH_RS09730 PF00589 Phage integrase family SPH_RS09730 PF02899 Phage integrase, N-terminal SAM-like domain SPH_RS09745 PF01725 Ham1 family SPH_RS09750 PF01177 Asp/Glu/Hydantoin racemase SPH_RS09755 PF03672 Uncharacterised protein family (UPF0154) SPH_RS09765 PF16657 Maltogenic Amylase, C-terminal domain SPH_RS09765 PF00128 Alpha amylase, catalytic domain SPH_RS09770 PF02378 Phosphotransferase system, EIIC SPH_RS09770 PF00367 phosphotransferase system, EIIB SPH_RS09775 PF07702 UTRA domain SPH_RS09775 PF00392 Bacterial regulatory proteins, gntR family SPH_RS09790 PF01610 Transposase SPH_RS09790 PF13683 Integrase core domain SPH_RS09795 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPH_RS09795 PF00005 ABC transporter SPH_RS09800 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPH_RS09800 PF00005 ABC transporter SPH_RS09805 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09805 PF12911 N-terminal TM domain of oligopeptide transport permease C SPH_RS09810 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09815 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS09825 PF00128 Alpha amylase, catalytic domain SPH_RS09830 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09835 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09840 PF01547 Bacterial extracellular solute-binding protein SPH_RS09845 PF16874 Glycosyl hydrolase family 36 C-terminal domain SPH_RS09845 PF16875 Glycosyl hydrolase family 36 N-terminal domain SPH_RS09850 PF12833 Helix-turn-helix domain SPH_RS09850 PF02311 AraC-like ligand binding domain SPH_RS09855 PF03099 Biotin/lipoate A/B protein ligase family SPH_RS09855 PF02237 Biotin protein ligase C terminal domain SPH_RS09865 PF13683 Integrase core domain SPH_RS09865 PF01610 Transposase SPH_RS09985 PF02631 RecX family SPH_RS09990 PF04167 Protein of unknown function (DUF402) SPH_RS10010 PF13683 Integrase core domain SPH_RS10010 PF01610 Transposase SPH_RS10015 PF00118 TCP-1/cpn60 chaperonin family SPH_RS10020 PF00166 Chaperonin 10 Kd subunit SPH_RS10025 PF00436 Single-strand binding protein family SPH_RS10030 PF00106 short chain dehydrogenase SPH_RS10035 PF14794 Domain of unknown function (DUF4479) SPH_RS10035 PF01588 Putative tRNA binding domain SPH_RS10040 PF00085 Thioredoxin SPH_RS10075 PF00005 ABC transporter SPH_RS10075 PF00664 ABC transporter transmembrane region SPH_RS10085 PF01047 MarR family SPH_RS10090 PF01709 Transcriptional regulator SPH_RS10095 PF01289 Thiol-activated cytolysin SPH_RS10095 PF17440 Thiol-activated cytolysin beta sandwich domain SPH_RS10135 PF00005 ABC transporter SPH_RS10135 PF08402 TOBE domain SPH_RS10140 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS10145 PF02308 MgtC family SPH_RS10155 PF00356 Bacterial regulatory proteins, lacI family SPH_RS10205 PF01510 N-acetylmuramoyl-L-alanine amidase SPH_RS10205 PF01473 Putative cell wall binding repeat SPH_RS10215 PF00154 recA bacterial DNA recombination protein SPH_RS10220 PF18146 Damage-inducible protein CinA KH domain SPH_RS10220 PF00994 Probable molybdopterin binding domain SPH_RS10220 PF02464 Competence-damaged protein SPH_RS10225 PF03816 Cell envelope-related transcriptional attenuator domain SPH_RS10235 PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPH_RS10265 PF00005 ABC transporter SPH_RS10275 PF00334 Nucleoside diphosphate kinase SPH_RS10280 PF04998 RNA polymerase Rpb1, domain 5 SPH_RS10280 PF00623 RNA polymerase Rpb1, domain 2 SPH_RS10280 PF05000 RNA polymerase Rpb1, domain 4 SPH_RS10280 PF04997 RNA polymerase Rpb1, domain 1 SPH_RS10280 PF04983 RNA polymerase Rpb1, domain 3 SPH_RS10285 PF10385 RNA polymerase beta subunit external 1 domain SPH_RS10285 PF04565 RNA polymerase Rpb2, domain 3 SPH_RS10285 PF04561 RNA polymerase Rpb2, domain 2 SPH_RS10285 PF04560 RNA polymerase Rpb2, domain 7 SPH_RS10285 PF00562 RNA polymerase Rpb2, domain 6 SPH_RS10285 PF04563 RNA polymerase beta subunit SPH_RS10295 PF00571 CBS domain SPH_RS10295 PF01595 Cyclin M transmembrane N-terminal domain SPH_RS10295 PF03471 Transporter associated domain SPH_RS10300 PF01223 DNA/RNA non-specific endonuclease SPH_RS10305 PF11772 DNA-directed RNA polymerase subunit beta SPH_RS10310 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS10320 PF13180 PDZ domain SPH_RS10320 PF05362 Lon protease (S16) C-terminal proteolytic domain SPH_RS10325 PF01467 Cytidylyltransferase-like SPH_RS10335 PF03590 Aspartate-ammonia ligase SPH_RS10340 PF01027 Inhibitor of apoptosis-promoting Bax1 SPH_RS10345 PF00588 SpoU rRNA Methylase family SPH_RS10345 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPH_RS10350 PF00708 Acylphosphatase SPH_RS10355 PF02096 60Kd inner membrane protein SPH_RS10360 PF04055 Radical SAM superfamily SPH_RS10365 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPH_RS10365 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPH_RS10370 PF09182 Bacterial purine repressor, N-terminal SPH_RS10370 PF00156 Phosphoribosyl transferase domain SPH_RS10375 PF01966 HD domain SPH_RS10375 PF01336 OB-fold nucleic acid binding domain SPH_RS10380 PF02646 RmuC family SPH_RS10385 PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain SPH_RS10385 PF04263 Thiamin pyrophosphokinase, catalytic domain SPH_RS10390 PF00834 Ribulose-phosphate 3 epimerase family SPH_RS10395 PF03193 RsgA GTPase SPH_RS10395 PF16745 RsgA N-terminal domain SPH_RS10400 PF00398 Ribosomal RNA adenine dimethylase SPH_RS10410 PF00005 ABC transporter SPH_RS10410 PF02687 FtsX-like permease family SPH_RS10410 PF12704 MacB-like periplasmic core domain SPH_RS10430 PF13662 Toprim domain SPH_RS10430 PF13331 Domain of unknown function (DUF4093) SPH_RS10435 PF01026 TatD related DNase SPH_RS10445 PF00468 Ribosomal protein L34 SPH_RS10450 PF00155 Aminotransferase class I and II SPH_RS10460 PF00582 Universal stress protein family SPH_RS10470 PF00710 Asparaginase, N-terminal SPH_RS10470 PF17763 Glutaminase/Asparaginase C-terminal domain SPH_RS10480 PF00356 Bacterial regulatory proteins, lacI family SPH_RS10485 PF00072 Response regulator receiver domain SPH_RS10485 PF00196 Bacterial regulatory proteins, luxR family SPH_RS10490 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS10490 PF07730 Histidine kinase SPH_RS10500 PF00005 ABC transporter SPH_RS10590 PF02357 Transcription termination factor nusG SPH_RS10590 PF00467 KOW motif SPH_RS10600 PF00471 Ribosomal protein L33 SPH_RS10605 PF00912 Transglycosylase SPH_RS10605 PF00905 Penicillin binding protein transpeptidase domain SPH_RS10610 PF00849 RNA pseudouridylate synthase SPH_RS10615 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPH_RS10615 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPH_RS10620 PF02687 FtsX-like permease family SPH_RS10620 PF12704 MacB-like periplasmic core domain SPH_RS10640 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain SPH_RS10640 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain SPH_RS10650 PF00005 ABC transporter SPH_RS10655 PF00392 Bacterial regulatory proteins, gntR family SPH_RS10655 PF07702 UTRA domain SPH_RS10660 PF00232 Glycosyl hydrolase family 1 SPH_RS10665 PF02378 Phosphotransferase system, EIIC SPH_RS10670 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS10675 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS10680 PF00171 Aldehyde dehydrogenase family SPH_RS10680 PF00465 Iron-containing alcohol dehydrogenase SPH_RS10690 PF01451 Low molecular weight phosphotyrosine protein phosphatase SPH_RS10700 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS10700 PF02780 Transketolase, C-terminal domain SPH_RS10700 PF02779 Transketolase, pyrimidine binding domain SPH_RS10715 PF00596 Class II Aldolase and Adducin N-terminal domain SPH_RS10720 PF01261 Xylose isomerase-like TIM barrel SPH_RS10725 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPH_RS10730 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS10735 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS10740 PF03611 PTS system sugar-specific permease component SPH_RS10750 PF01424 R3H domain SPH_RS10750 PF14804 Jag N-terminus SPH_RS10755 PF02096 60Kd inner membrane protein SPH_RS10760 PF00825 Ribonuclease P SPH_RS10765 PF00871 Acetokinase family SPH_RS10805 PF07963 Prokaryotic N-terminal methylation motif SPH_RS10810 PF00482 Type II secretion system (T2SS), protein F SPH_RS10815 PF00437 Type II/IV secretion system protein SPH_RS10825 PF01610 Transposase SPH_RS10825 PF13683 Integrase core domain SPH_RS10830 PF00107 Zinc-binding dehydrogenase SPH_RS10830 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS10830 PF13823 Alcohol dehydrogenase GroES-associated SPH_RS10835 PF01979 Amidohydrolase family SPH_RS10840 PF01757 Acyltransferase family SPH_RS10845 PF01702 Queuine tRNA-ribosyltransferase SPH_RS10875 PF00475 Imidazoleglycerol-phosphate dehydratase SPH_RS10875 PF08645 Polynucleotide kinase 3 phosphatase SPH_RS10880 PF01554 MatE SPH_RS10885 PF14821 Threonine synthase N terminus SPH_RS10885 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS10945 PF00589 Phage integrase family SPH_RS10945 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS10950 PF13291 ACT domain SPH_RS10950 PF04607 Region found in RelA / SpoT proteins SPH_RS10950 PF02824 TGS domain SPH_RS10960 PF00149 Calcineurin-like phosphoesterase SPH_RS10965 PF01610 Transposase SPH_RS10965 PF13683 Integrase core domain SPH_RS11050 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS11055 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPH_RS11060 PF00342 Phosphoglucose isomerase SPH_RS11070 PF07722 Peptidase C26 SPH_RS11075 PF00005 ABC transporter SPH_RS11075 PF00664 ABC transporter transmembrane region SPH_RS11085 PF00664 ABC transporter transmembrane region SPH_RS11085 PF00005 ABC transporter SPH_RS11090 PF00488 MutS domain V SPH_RS11090 PF05190 MutS family domain IV SPH_RS11090 PF05192 MutS domain III SPH_RS11090 PF05188 MutS domain II SPH_RS11090 PF01624 MutS domain I SPH_RS11095 PF01316 Arginine repressor, DNA binding domain SPH_RS11095 PF02863 Arginine repressor, C-terminal domain SPH_RS11100 PF03485 Arginyl tRNA synthetase N terminal domain SPH_RS11100 PF05746 DALR anticodon binding domain SPH_RS11100 PF00750 tRNA synthetases class I (R) SPH_RS11115 PF00486 Transcriptional regulatory protein, C terminal SPH_RS11115 PF00072 Response regulator receiver domain SPH_RS11120 PF16736 Single Cache-like SPH_RS11120 PF00989 PAS fold SPH_RS11120 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS11120 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS11125 PF12849 PBP superfamily domain SPH_RS11130 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11135 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11140 PF00005 ABC transporter SPH_RS11145 PF01895 PhoU domain SPH_RS11160 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPH_RS11160 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPH_RS11165 PF00483 Nucleotidyl transferase SPH_RS11185 PF01812 5-formyltetrahydrofolate cyclo-ligase family SPH_RS11190 PF07687 Peptidase dimerisation domain SPH_RS11190 PF01546 Peptidase family M20/M25/M40 SPH_RS11195 PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal SPH_RS11195 PF14602 Hexapeptide repeat of succinyl-transferase SPH_RS11195 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS11200 PF00892 EamA-like transporter family SPH_RS11205 PF00905 Penicillin binding protein transpeptidase domain SPH_RS11205 PF00912 Transglycosylase SPH_RS11210 PF01479 S4 domain SPH_RS11210 PF00579 tRNA synthetases class I (W and Y) SPH_RS11215 PF00403 Heavy-metal-associated domain SPH_RS11225 PF13847 Methyltransferase domain SPH_RS11245 PF00343 Carbohydrate phosphorylase SPH_RS11250 PF02446 4-alpha-glucanotransferase SPH_RS11260 PF13416 Bacterial extracellular solute-binding protein SPH_RS11265 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11270 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11280 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPH_RS11280 PF00356 Bacterial regulatory proteins, lacI family SPH_RS11285 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPH_RS11285 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPH_RS11290 PF00152 tRNA synthetases class II (D, K and N) SPH_RS11290 PF01336 OB-fold nucleic acid binding domain SPH_RS11290 PF02938 GAD domain SPH_RS11320 PF01381 Helix-turn-helix SPH_RS11335 PF13393 Histidyl-tRNA synthetase SPH_RS11335 PF03129 Anticodon binding domain SPH_RS11350 PF01883 Iron-sulfur cluster assembly protein SPH_RS11360 PF00920 Dehydratase family SPH_RS11365 PF02779 Transketolase, pyrimidine binding domain SPH_RS11365 PF02780 Transketolase, C-terminal domain SPH_RS11365 PF13292 1-deoxy-D-xylulose-5-phosphate synthase SPH_RS11370 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS11375 PF03611 PTS system sugar-specific permease component SPH_RS11385 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS11400 PF01783 Ribosomal L32p protein family SPH_RS11405 PF00471 Ribosomal protein L33 SPH_RS11440 PF00480 ROK family SPH_RS11445 PF07748 Glycosyl hydrolases family 38 C-terminal domain SPH_RS11445 PF01074 Glycosyl hydrolases family 38 N-terminal domain SPH_RS11445 PF18438 Glycosyl hydrolases family 38 C-terminal domain 1 SPH_RS11445 PF17677 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SPH_RS11445 PF09261 Alpha mannosidase middle domain SPH_RS11455 PF17678 Glycosyl hydrolase family 92 N-terminal domain SPH_RS11455 PF07971 Glycosyl hydrolase family 92 SPH_RS11470 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPH_RS11470 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPH_RS11475 PF00696 Amino acid kinase family SPH_RS11480 PF03606 C4-dicarboxylate anaerobic carrier SPH_RS11485 PF01546 Peptidase family M20/M25/M40 SPH_RS11495 PF07501 G5 domain SPH_RS11495 PF00746 LPXTG cell wall anchor motif SPH_RS11495 PF04650 YSIRK type signal peptide SPH_RS11495 PF00728 Glycosyl hydrolase family 20, catalytic domain SPH_RS11510 PF00465 Iron-containing alcohol dehydrogenase SPH_RS11515 PF07882 L-fucose isomerase, second N-terminal domain SPH_RS11515 PF02952 L-fucose isomerase, C-terminal domain SPH_RS11515 PF07881 L-fucose isomerase, first N-terminal domain SPH_RS11520 PF08305 NPCBM/NEW2 domain SPH_RS11520 PF08306 Glycosyl hydrolase family 98 SPH_RS11520 PF08307 Glycosyl hydrolase family 98 C-terminal domain SPH_RS11530 PF03613 PTS system mannose/fructose/sorbose family IID component SPH_RS11540 PF03830 PTS system sorbose subfamily IIB component SPH_RS11550 PF05025 RbsD / FucU transport protein family SPH_RS11555 PF00596 Class II Aldolase and Adducin N-terminal domain SPH_RS11560 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPH_RS11560 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPH_RS11565 PF08220 DeoR-like helix-turn-helix domain SPH_RS11565 PF00455 DeoR C terminal sensor domain SPH_RS11570 PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment SPH_RS11570 PF01297 Zinc-uptake complex component A periplasmic SPH_RS11575 PF00950 ABC 3 transport family SPH_RS11580 PF00005 ABC transporter SPH_RS11585 PF01047 MarR family SPH_RS11590 PF04914 DltD protein SPH_RS11595 PF00550 Phosphopantetheine attachment site SPH_RS11600 PF03062 MBOAT, membrane-bound O-acyltransferase family SPH_RS11605 PF13193 AMP-binding enzyme C-terminal domain SPH_RS11605 PF00501 AMP-binding enzyme SPH_RS11615 PF07690 Major Facilitator Superfamily SPH_RS11620 PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) SPH_RS11640 PF00230 Major intrinsic protein SPH_RS11645 PF16901 C-terminal domain of alpha-glycerophosphate oxidase SPH_RS11645 PF01266 FAD dependent oxidoreductase SPH_RS11650 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPH_RS11650 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPH_RS11660 PF01430 Hsp33 protein SPH_RS11665 PF01207 Dihydrouridine synthase (Dus) SPH_RS11670 PF05062 RICH domain SPH_RS11670 PF00746 LPXTG cell wall anchor motif SPH_RS11670 PF16828 GAG-binding domain on surface antigen SPH_RS11670 PF04650 YSIRK type signal peptide SPH_RS11680 PF01610 Transposase SPH_RS11680 PF13683 Integrase core domain SPH_RS11685 PF18080 Galactose mutarotase-like fold domain SPH_RS11685 PF17995 Endo-alpha-N-acetylgalactosaminidase N-terminal SPH_RS11685 PF17451 Glycosyl hydrolase 101 beta sandwich domain SPH_RS11685 PF12905 Endo-alpha-N-acetylgalactosaminidase SPH_RS11685 PF04650 YSIRK type signal peptide SPH_RS11685 PF00754 F5/8 type C domain SPH_RS11685 PF17974 Galactose-binding domain-like SPH_RS11690 PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SPH_RS11695 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS11695 PF00672 HAMP domain SPH_RS11695 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS11700 PF00486 Transcriptional regulatory protein, C terminal SPH_RS11700 PF00072 Response regulator receiver domain SPH_RS11705 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS11705 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS11705 PF02861 Clp amino terminal domain, pathogenicity island component SPH_RS11705 PF17871 AAA lid domain SPH_RS11705 PF07724 AAA domain (Cdc48 subfamily) SPH_RS11710 PF05848 CtsR N-terminal HTH domain SPH_RS11710 PF17727 CtsR C-terminal dimerization domain SPH_RS11715 PF00005 ABC transporter SPH_RS11720 PF09084 NMT1/THI5 like SPH_RS11725 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11745 PF00772 DnaB-like helicase N terminal domain SPH_RS11745 PF03796 DnaB-like helicase C terminal domain SPH_RS11750 PF03948 Ribosomal protein L9, C-terminal domain SPH_RS11750 PF01281 Ribosomal protein L9, N-terminal domain SPH_RS11755 PF02272 DHHA1 domain SPH_RS11755 PF01368 DHH family SPH_RS11760 PF02482 Sigma 54 modulation protein / S30EA ribosomal protein SPH_RS11760 PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus SPH_RS11770 PF04851 Type III restriction enzyme, res subunit SPH_RS11770 PF00271 Helicase conserved C-terminal domain SPH_RS11775 PF09186 Domain of unknown function (DUF1949) SPH_RS11775 PF01205 Uncharacterized protein family UPF0029 SPH_RS11780 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS11785 PF00889 Elongation factor TS SPH_RS11790 PF00318 Ribosomal protein S2 SPH_RS11795 PF01476 LysM domain SPH_RS11795 PF05257 CHAP domain SPH_RS11805 PF04085 rod shape-determining protein MreC SPH_RS11810 PF02361 Cobalt transport protein SPH_RS11815 PF00005 ABC transporter SPH_RS11820 PF00005 ABC transporter SPH_RS11825 PF01066 CDP-alcohol phosphatidyltransferase SPH_RS11835 PF05193 Peptidase M16 inactive domain SPH_RS11835 PF00675 Insulinase (Peptidase family M16) SPH_RS11840 PF00675 Insulinase (Peptidase family M16) SPH_RS11840 PF05193 Peptidase M16 inactive domain SPH_RS11850 PF02463 RecF/RecN/SMC N terminal domain SPH_RS11855 PF00571 CBS domain SPH_RS11855 PF00478 IMP dehydrogenase / GMP reductase domain SPH_RS11860 PF00579 tRNA synthetases class I (W and Y) SPH_RS11865 PF00005 ABC transporter SPH_RS11865 PF12848 ABC transporter SPH_RS11910 PF03047 COMC family SPH_RS11925 PF13180 PDZ domain SPH_RS11930 PF02195 ParB-like nuclease domain SPH_RS11930 PF17762 HTH domain found in ParB protein