SPH_RS00005 PF00308 Bacterial dnaA protein SPH_RS00005 PF08299 Bacterial dnaA protein helix-turn-helix SPH_RS00010 PF00712 DNA polymerase III beta subunit, N-terminal domain SPH_RS00010 PF02767 DNA polymerase III beta subunit, central domain SPH_RS00010 PF02768 DNA polymerase III beta subunit, C-terminal domain SPH_RS00015 PF06107 SPH_RS00015 SPH_RS00020 PF01926 50S ribosome-binding GTPase SPH_RS00020 PF06071 Protein of unknown function (DUF933) SPH_RS00025 PF01195 Peptidyl-tRNA hydrolase SPH_RS00030 PF00270 DEAD/DEAH box helicase SPH_RS00030 PF00271 Helicase conserved C-terminal domain SPH_RS00030 PF02559 CarD-like/TRCF domain SPH_RS00030 PF03461 TRCF domain SPH_RS00035 PF01479 S4 domain SPH_RS00040 PF04977 Septum formation initiator SPH_RS00050 PF13354 Beta-lactamase enzyme family SPH_RS00055 PF01171 PP-loop family SPH_RS00055 PF11734 TilS substrate C-terminal domain SPH_RS00060 PF00156 Phosphoribosyl transferase domain SPH_RS00065 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS00065 PF01434 Peptidase family M41 SPH_RS00065 PF06480 FtsH Extracellular SPH_RS00115 PF13542 SPH_RS00115 SPH_RS00125 PF00709 Adenylosuccinate synthetase SPH_RS00130 PF00589 Phage integrase family SPH_RS00145 PF00717 Peptidase S24-like SPH_RS00145 PF13443 Cro/C1-type HTH DNA-binding domain SPH_RS00150 PF01381 Helix-turn-helix SPH_RS00155 PF13643 SPH_RS00155 SPH_RS00160 PF02498 SPH_RS00160 SPH_RS00160 PF10552 SPH_RS00160 SPH_RS00180 PF07261 Replication initiation and membrane attachment SPH_RS00180 PF09681 SPH_RS00180 SPH_RS00185 PF01695 IstB-like ATP binding protein SPH_RS00215 PF00589 Phage integrase family SPH_RS00220 PF01844 HNH endonuclease SPH_RS00230 PF03354 SPH_RS00230 SPH_RS00235 PF04860 Phage portal protein SPH_RS00240 PF04586 SPH_RS00240 SPH_RS00245 PF05065 Phage capsid family SPH_RS00255 PF05521 Phage head-tail joining protein SPH_RS00280 PF10145 SPH_RS00280 SPH_RS00290 PF13884 Chaperone of endosialidase SPH_RS00305 PF05105 SPH_RS00305 SPH_RS00310 PF09682 SPH_RS00310 SPH_RS00315 PF01473 Putative cell wall binding repeat SPH_RS00325 PF14437 SPH_RS00325 SPH_RS00330 PF00589 Phage integrase family SPH_RS00330 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS00340 PF06114 Domain of unknown function (DUF955) SPH_RS00345 PF01381 Helix-turn-helix SPH_RS00350 PF13443 Cro/C1-type HTH DNA-binding domain SPH_RS00355 PF03374 SPH_RS00355 SPH_RS00355 PF08346 SPH_RS00355 SPH_RS00375 PF04404 SPH_RS00375 SPH_RS00380 PF07083 SPH_RS00380 SPH_RS00385 PF00436 Single-strand binding protein family SPH_RS00430 PF07852 SPH_RS00430 SPH_RS00445 PF02195 ParB-like nuclease domain SPH_RS00445 PF14386 SPH_RS00445 SPH_RS00460 PF04466 Phage terminase large subunit SPH_RS00465 PF05133 Phage portal protein, SPP1 Gp6-like SPH_RS00470 PF06152 SPH_RS00470 SPH_RS00475 PF06810 SPH_RS00475 SPH_RS00495 PF10665 SPH_RS00495 SPH_RS00500 PF11114 SPH_RS00500 SPH_RS00505 PF12691 SPH_RS00505 SPH_RS00520 PF06854 SPH_RS00520 SPH_RS00530 PF05709 Phage tail protein SPH_RS00545 PF05895 SPH_RS00545 SPH_RS00555 PF05105 SPH_RS00555 SPH_RS00560 PF09682 SPH_RS00560 SPH_RS00570 PF00692 dUTPase SPH_RS00575 PF00300 Histidine phosphatase superfamily (branch 1) SPH_RS00580 PF13481 AAA domain SPH_RS00580 PF13541 Subunit ChlI of Mg-chelatase SPH_RS00585 PF00484 Carbonic anhydrase SPH_RS00590 PF13367 SPH_RS00590 SPH_RS00595 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPH_RS00595 PF14572 Phosphoribosyl synthetase-associated domain SPH_RS00600 PF14690 SPH_RS00600 SPH_RS00610 PF12784 SPH_RS00610 SPH_RS00615 PF00476 DNA polymerase family A SPH_RS00615 PF01367 5'-3' exonuclease, C-terminal SAM fold SPH_RS00615 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain SPH_RS00620 PF13380 CoA binding domain SPH_RS00630 PF03601 SPH_RS00630 SPH_RS00635 PF00155 Aminotransferase class I and II SPH_RS00640 PF02565 Recombination protein O C terminal SPH_RS00640 PF11967 Recombination protein O N terminal SPH_RS00645 PF02504 Fatty acid synthesis protein SPH_RS00650 PF00550 Phosphopantetheine attachment site SPH_RS00655 PF13359 SPH_RS00655 SPH_RS00660 PF10439 SPH_RS00660 SPH_RS00680 PF09221 Bacteriocin class IId cyclical uberolysin-like SPH_RS00690 PF01944 SPH_RS00690 SPH_RS00695 PF00005 ABC transporter SPH_RS00710 PF00005 ABC transporter SPH_RS00710 PF00664 ABC transporter transmembrane region SPH_RS00710 PF03412 Peptidase C39 family SPH_RS00715 PF13437 HlyD family secretion protein SPH_RS00720 PF01259 SAICAR synthetase SPH_RS00730 PF02769 AIR synthase related protein, C-terminal domain SPH_RS00730 PF13507 CobB/CobQ-like glutamine amidotransferase domain SPH_RS00735 PF00156 Phosphoribosyl transferase domain SPH_RS00735 PF13522 Glutamine amidotransferase domain SPH_RS00740 PF00586 AIR synthase related protein, N-terminal domain SPH_RS00740 PF02769 AIR synthase related protein, C-terminal domain SPH_RS00745 PF00551 Formyl transferase SPH_RS00750 PF04892 SPH_RS00750 SPH_RS00755 PF01808 AICARFT/IMPCHase bienzyme SPH_RS00755 PF02142 MGS-like domain SPH_RS00760 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPH_RS00760 PF02843 Phosphoribosylglycinamide synthetase, C domain SPH_RS00760 PF02844 Phosphoribosylglycinamide synthetase, N domain SPH_RS00765 PF00731 AIR carboxylase SPH_RS00770 PF02222 ATP-grasp domain SPH_RS00780 PF00206 Lyase SPH_RS00780 PF10397 Adenylosuccinate lyase C-terminus SPH_RS00785 PF00728 Glycosyl hydrolase family 20, catalytic domain SPH_RS00785 PF00746 SPH_RS00785 SPH_RS00785 PF04650 SPH_RS00785 SPH_RS00785 PF07501 G5 domain SPH_RS00790 PF00392 Bacterial regulatory proteins, gntR family SPH_RS00790 PF07702 UTRA domain SPH_RS00795 PF01301 Glycosyl hydrolases family 35 SPH_RS00800 PF03830 PTS system sorbose subfamily IIB component SPH_RS00805 PF03609 SPH_RS00805 SPH_RS00810 PF03613 SPH_RS00810 SPH_RS00815 PF03610 PTS system fructose IIA component SPH_RS00820 PF01380 SIS domain SPH_RS00825 PF01263 Aldose 1-epimerase SPH_RS00830 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPH_RS00835 PF02583 Metal-sensitive transcriptional repressor SPH_RS00845 PF01048 Phosphorylase superfamily SPH_RS00860 PF02386 Cation transport protein SPH_RS00865 PF02254 TrkA-N domain SPH_RS00870 PF00535 Glycosyl transferase family 2 SPH_RS00880 PF04650 SPH_RS00880 SPH_RS00880 PF11966 SPH_RS00880 SPH_RS00885 PF00072 Response regulator receiver domain SPH_RS00885 PF00486 Transcriptional regulatory protein, C terminal SPH_RS00890 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS00890 PF00672 HAMP domain SPH_RS00890 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS00895 PF00163 Ribosomal protein S4/S9 N-terminal domain SPH_RS00895 PF01479 S4 domain SPH_RS00900 PF01710 Transposase SPH_RS00915 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS00920 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS00930 PF12010 SPH_RS00930 SPH_RS00935 PF00581 Rhodanese-like domain SPH_RS00935 PF12368 SPH_RS00935 SPH_RS00950 PF13349 SPH_RS00950 SPH_RS00955 PF08006 SPH_RS00955 SPH_RS00960 PF03551 Transcriptional regulator PadR-like family SPH_RS00965 PF07690 Major Facilitator Superfamily SPH_RS00970 PF00535 Glycosyl transferase family 2 SPH_RS00975 PF02719 Polysaccharide biosynthesis protein SPH_RS00975 PF13727 CoA-binding domain SPH_RS00980 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS00985 PF03313 SPH_RS00985 SPH_RS00990 PF01842 ACT domain SPH_RS00990 PF03315 Serine dehydratase beta chain SPH_RS00995 PF01476 LysM domain SPH_RS01000 PF12844 Helix-turn-helix domain SPH_RS01015 PF09683 Bacteriocin (Lactococcin_972) SPH_RS01025 PF00005 ABC transporter SPH_RS01030 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS01035 PF00764 Arginosuccinate synthase SPH_RS01040 PF00206 Lyase SPH_RS01040 PF14698 Argininosuccinate lyase C-terminal SPH_RS01110 PF01473 Putative cell wall binding repeat SPH_RS01115 PF03054 tRNA methyl transferase SPH_RS01120 PF00293 NUDIX domain SPH_RS01125 PF01134 Glucose inhibited division protein A SPH_RS01125 PF13932 GidA associated domain 3 SPH_RS01135 PF00753 Metallo-beta-lactamase superfamily SPH_RS01135 PF07521 RNA-metabolising metallo-beta-lactamase SPH_RS01140 PF07288 Protein of unknown function (DUF1447) SPH_RS01160 PF00814 Glycoprotease family SPH_RS01165 PF13673 Acetyltransferase (GNAT) domain SPH_RS01170 PF00814 Glycoprotease family SPH_RS01175 PF01610 SPH_RS01175 SPH_RS01180 PF01610 SPH_RS01180 SPH_RS01180 PF13542 SPH_RS01180 SPH_RS01180 PF14690 SPH_RS01180 SPH_RS01190 PF01710 Transposase SPH_RS01195 PF00534 Glycosyl transferases group 1 SPH_RS01195 PF13439 Glycosyltransferase Family 4 SPH_RS01200 PF00535 Glycosyl transferase family 2 SPH_RS01205 PF00005 ABC transporter SPH_RS01205 PF00664 ABC transporter transmembrane region SPH_RS01215 PF02585 GlcNAc-PI de-N-acetylase SPH_RS01220 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPH_RS01220 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPH_RS01220 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPH_RS01225 PF01381 Helix-turn-helix SPH_RS01235 PF02517 CAAX protease self-immunity SPH_RS01240 PF07690 Major Facilitator Superfamily SPH_RS01250 PF03591 SPH_RS01250 SPH_RS01255 PF05437 SPH_RS01255 SPH_RS01260 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS01265 PF03180 NLPA lipoprotein SPH_RS01270 PF01546 Peptidase family M20/M25/M40 SPH_RS01270 PF07687 Peptidase dimerisation domain SPH_RS01275 PF00005 ABC transporter SPH_RS01275 PF09383 NIL domain SPH_RS01280 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS01285 PF09605 SPH_RS01285 SPH_RS01290 PF04854 SPH_RS01290 SPH_RS01295 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS01295 PF06580 SPH_RS01295 SPH_RS01300 PF00072 Response regulator receiver domain SPH_RS01300 PF12833 Helix-turn-helix domain SPH_RS01310 PF07972 NrdI Flavodoxin like SPH_RS01315 PF13701 SPH_RS01315 SPH_RS01320 PF01566 SPH_RS01320 SPH_RS01325 PF11457 SPH_RS01325 SPH_RS01330 PF04397 LytTr DNA-binding domain SPH_RS01335 PF01119 DNA mismatch repair protein, C-terminal domain SPH_RS01335 PF08676 MutL C terminal dimerisation domain SPH_RS01335 PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS01340 PF00885 6,7-dimethyl-8-ribityllumazine synthase SPH_RS01345 PF00925 GTP cyclohydrolase II SPH_RS01345 PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase SPH_RS01350 PF00677 Lumazine binding domain SPH_RS01355 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS01355 PF01872 RibD C-terminal domain SPH_RS01360 PF01330 RuvA N terminal domain SPH_RS01360 PF07499 RuvA, C-terminal domain SPH_RS01360 PF14520 Helix-hairpin-helix domain SPH_RS01365 PF03352 Methyladenine glycosylase SPH_RS01370 PF02517 CAAX protease self-immunity SPH_RS01375 PF02016 LD-carboxypeptidase SPH_RS01380 PF06570 SPH_RS01380 SPH_RS01385 PF01544 CorA-like Mg2+ transporter protein SPH_RS01390 PF00589 Phage integrase family SPH_RS01390 PF14659 Phage integrase, N-terminal SAM-like domain SPH_RS01395 PF03965 Penicillinase repressor SPH_RS01395 PF04326 Divergent AAA domain SPH_RS01395 PF13749 ATP-dependent DNA helicase recG C-terminal SPH_RS01400 PF01381 Helix-turn-helix SPH_RS01410 PF09669 SPH_RS01410 SPH_RS01440 PF08708 Primase C terminal 1 (PriCT-1) SPH_RS01445 PF08706 SPH_RS01445 SPH_RS01460 PF07374 SPH_RS01460 SPH_RS01465 PF00005 ABC transporter SPH_RS01470 PF00557 Metallopeptidase family M24 SPH_RS01470 PF01321 Creatinase/Prolidase N-terminal domain SPH_RS01475 PF03960 ArsC family SPH_RS01485 PF06135 SPH_RS01485 SPH_RS01490 PF03652 Uncharacterised protein family (UPF0081) SPH_RS01495 PF06949 SPH_RS01495 SPH_RS01500 PF08245 Mur ligase middle domain SPH_RS01505 PF12182 Bacterial lipoprotein SPH_RS01510 PF13091 PLD-like domain SPH_RS01510 PF13396 SPH_RS01510 SPH_RS01525 PF03477 ATP cone domain SPH_RS01525 PF13597 Anaerobic ribonucleoside-triphosphate reductase SPH_RS01535 PF13302 Acetyltransferase (GNAT) domain SPH_RS01540 PF13353 4Fe-4S single cluster domain SPH_RS01545 PF00485 Phosphoribulokinase / Uridine kinase family SPH_RS01550 PF00338 Ribosomal protein S10p/S20e SPH_RS01555 PF00297 Ribosomal protein L3 SPH_RS01560 PF00573 Ribosomal protein L4/L1 family SPH_RS01565 PF00276 Ribosomal protein L23 SPH_RS01570 PF00181 Ribosomal Proteins L2, RNA binding domain SPH_RS01570 PF03947 Ribosomal Proteins L2, C-terminal domain SPH_RS01575 PF00203 Ribosomal protein S19 SPH_RS01580 PF00237 Ribosomal protein L22p/L17e SPH_RS01585 PF00189 Ribosomal protein S3, C-terminal domain SPH_RS01585 PF07650 KH domain SPH_RS01590 PF00252 Ribosomal protein L16p/L10e SPH_RS01595 PF00831 Ribosomal L29 protein SPH_RS01600 PF00366 Ribosomal protein S17 SPH_RS01605 PF00238 Ribosomal protein L14p/L23e SPH_RS01610 PF00467 KOW motif SPH_RS01610 PF17136 SPH_RS01610 SPH_RS01615 PF00281 Ribosomal protein L5 SPH_RS01615 PF00673 ribosomal L5P family C-terminus SPH_RS01620 PF00253 Ribosomal protein S14p/S29e SPH_RS01625 PF00410 Ribosomal protein S8 SPH_RS01630 PF00347 Ribosomal protein L6 SPH_RS01635 PF00861 Ribosomal L18p/L5e family SPH_RS01640 PF00333 Ribosomal protein S5, N-terminal domain SPH_RS01640 PF03719 Ribosomal protein S5, C-terminal domain SPH_RS01645 PF00327 Ribosomal protein L30p/L7e SPH_RS01650 PF00828 Ribosomal protein L18e/L15 SPH_RS01655 PF00344 SecY translocase SPH_RS01660 PF00406 Adenylate kinase SPH_RS01665 PF01176 Translation initiation factor 1A / IF-1 SPH_RS01670 PF00444 Ribosomal protein L36 SPH_RS01675 PF00416 Ribosomal protein S13/S18 SPH_RS01680 PF00411 Ribosomal protein S11 SPH_RS01685 PF01000 RNA polymerase Rpb3/RpoA insert domain SPH_RS01685 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain SPH_RS01685 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain SPH_RS01690 PF01196 Ribosomal protein L17 SPH_RS01695 PF13740 ACT domain SPH_RS01700 PF05167 Uncharacterised ACR (DUF711) SPH_RS01705 PF00300 Histidine phosphatase superfamily (branch 1) SPH_RS01715 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS01720 PF00005 ABC transporter SPH_RS01720 PF08402 TOBE domain SPH_RS01725 PF13343 Bacterial extracellular solute-binding protein SPH_RS01730 PF13531 Bacterial extracellular solute-binding protein SPH_RS01735 PF12833 Helix-turn-helix domain SPH_RS01745 PF00072 Response regulator receiver domain SPH_RS01755 PF04055 Radical SAM superfamily SPH_RS01755 PF13353 4Fe-4S single cluster domain SPH_RS01760 PF00455 SPH_RS01760 SPH_RS01760 PF08220 DeoR-like helix-turn-helix domain SPH_RS01765 PF04198 Putative sugar-binding domain SPH_RS01770 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS01775 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS01780 PF02378 Phosphotransferase system, EIIC SPH_RS01785 PF01228 Glycine radical SPH_RS01785 PF02901 Pyruvate formate lyase SPH_RS01790 PF00923 Transaldolase SPH_RS01795 PF00465 Iron-containing alcohol dehydrogenase SPH_RS01800 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS01800 PF08264 Anticodon-binding domain of tRNA SPH_RS01800 PF09334 tRNA synthetases class I (M) SPH_RS01800 PF13603 Leucyl-tRNA synthetase, Domain 2 SPH_RS01810 PF13302 Acetyltransferase (GNAT) domain SPH_RS01815 PF13673 Acetyltransferase (GNAT) domain SPH_RS01820 PF13955 Toxin Fst, type I toxin-antitoxin system SPH_RS01825 PF05491 Holliday junction DNA helicase ruvB C-terminus SPH_RS01825 PF05496 Holliday junction DNA helicase ruvB N-terminus SPH_RS01830 PF06042 Bacterial protein of unknown function (DUF925) SPH_RS01835 PF01255 Putative undecaprenyl diphosphate synthase SPH_RS01840 PF01148 Cytidylyltransferase family SPH_RS01845 PF02163 Peptidase family M50 SPH_RS01850 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS01850 PF03129 Anticodon binding domain SPH_RS01850 PF04073 Aminoacyl-tRNA editing domain SPH_RS01855 PF00232 Glycosyl hydrolase family 1 SPH_RS01860 PF01380 SIS domain SPH_RS01860 PF13522 Glutamine amidotransferase domain SPH_RS01870 PF00296 Luciferase-like monooxygenase SPH_RS01875 PF00128 Alpha amylase, catalytic domain SPH_RS01875 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS01875 PF03714 Bacterial pullanase-associated domain SPH_RS01875 PF04650 SPH_RS01875 SPH_RS01880 PF00164 Ribosomal protein S12/S23 SPH_RS01885 PF00177 Ribosomal protein S7p/S5e SPH_RS01890 PF00009 Elongation factor Tu GTP binding domain SPH_RS01890 PF00679 Elongation factor G C-terminus SPH_RS01890 PF03144 Elongation factor Tu domain 2 SPH_RS01890 PF03764 Elongation factor G, domain IV SPH_RS01890 PF14492 Elongation Factor G, domain II SPH_RS01895 PF00929 Exonuclease SPH_RS01895 PF02811 PHP domain SPH_RS01895 PF07733 Bacterial DNA polymerase III alpha subunit SPH_RS01895 PF11490 SPH_RS01895 SPH_RS01895 PF14480 SPH_RS01895 SPH_RS01900 PF04221 RelB antitoxin SPH_RS01905 PF15738 SPH_RS01905 SPH_RS01915 PF02073 Thermophilic metalloprotease (M29) SPH_RS01920 PF01844 HNH endonuclease SPH_RS01925 PF00849 RNA pseudouridylate synthase SPH_RS01925 PF01479 S4 domain SPH_RS01935 PF03051 Peptidase C1-like family SPH_RS01940 PF03613 SPH_RS01940 SPH_RS01945 PF03609 SPH_RS01945 SPH_RS01950 PF03610 PTS system fructose IIA component SPH_RS01950 PF03830 PTS system sorbose subfamily IIB component SPH_RS01955 PF00107 Zinc-binding dehydrogenase SPH_RS01955 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS01960 PF08282 haloacid dehalogenase-like hydrolase SPH_RS01965 PF00860 Permease family SPH_RS01970 PF02517 CAAX protease self-immunity SPH_RS01980 PF00809 Pterin binding enzyme SPH_RS01985 PF02875 Mur ligase family, glutamate ligase domain SPH_RS01985 PF08245 Mur ligase middle domain SPH_RS01990 PF01227 GTP cyclohydrolase I SPH_RS01995 PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SPH_RS01995 PF02152 Dihydroneopterin aldolase SPH_RS02000 PF06124 Staphylococcal protein of unknown function (DUF960) SPH_RS02005 PF00572 Ribosomal protein L13 SPH_RS02010 PF00380 Ribosomal protein S9/S16 SPH_RS02015 PF00589 Phage integrase family SPH_RS02040 PF00589 Phage integrase family SPH_RS02045 PF13173 AAA domain SPH_RS02045 PF13635 SPH_RS02045 SPH_RS02055 PF01055 Glycosyl hydrolases family 31 SPH_RS02060 PF00255 Glutathione peroxidase SPH_RS02065 PF00746 SPH_RS02065 SPH_RS02065 PF02278 Polysaccharide lyase family 8, super-sandwich domain SPH_RS02065 PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain SPH_RS02065 PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain SPH_RS02070 PF01797 Transposase IS200 like SPH_RS02075 PF01081 KDPG and KHG aldolase SPH_RS02080 PF00294 pfkB family carbohydrate kinase SPH_RS02085 PF02502 Ribose/Galactose Isomerase SPH_RS02085 PF12408 Ribose-5-phosphate isomerase SPH_RS02090 PF13561 Enoyl-(Acyl carrier protein) reductase SPH_RS02095 PF03610 PTS system fructose IIA component SPH_RS02100 PF07470 Glycosyl Hydrolase Family 88 SPH_RS02105 PF03830 PTS system sorbose subfamily IIB component SPH_RS02110 PF03609 SPH_RS02110 SPH_RS02115 PF03613 SPH_RS02115 SPH_RS02120 PF02699 Preprotein translocase subunit SPH_RS02125 PF07940 Heparinase II/III-like protein SPH_RS02125 PF16889 SPH_RS02125 SPH_RS02130 PF00356 Bacterial regulatory proteins, lacI family SPH_RS02130 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPH_RS02145 PF11683 SPH_RS02145 SPH_RS02150 PF01381 Helix-turn-helix SPH_RS02155 PF01795 MraW methylase family SPH_RS02165 PF00905 Penicillin binding protein transpeptidase domain SPH_RS02165 PF03717 Penicillin-binding Protein dimerisation domain SPH_RS02165 PF03793 PASTA domain SPH_RS02170 PF00953 Glycosyl transferase family 4 SPH_RS02170 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SPH_RS02175 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS02175 PF07724 AAA domain (Cdc48 subfamily) SPH_RS02175 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS02180 PF02664 S-Ribosylhomocysteinase (LuxS) SPH_RS02185 PF08903 Domain of unknown function (DUF1846) SPH_RS02190 PF00128 Alpha amylase, catalytic domain SPH_RS02190 PF16657 SPH_RS02190 SPH_RS02200 PF13358 DDE superfamily endonuclease SPH_RS02205 PF01710 Transposase SPH_RS02210 PF02916 DNA polymerase processivity factor SPH_RS02210 PF03816 Cell envelope-related transcriptional attenuator domain SPH_RS02220 PF02706 Chain length determinant protein SPH_RS02225 PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain SPH_RS02230 PF02397 SPH_RS02230 SPH_RS02235 PF03808 SPH_RS02235 SPH_RS02240 PF04991 SPH_RS02240 SPH_RS02245 PF00535 Glycosyl transferase family 2 SPH_RS02260 PF02350 UDP-N-acetylglucosamine 2-epimerase SPH_RS02265 PF00483 Nucleotidyl transferase SPH_RS02270 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SPH_RS02275 PF16363 SPH_RS02275 SPH_RS02280 PF04321 RmlD substrate binding domain SPH_RS02285 PF03050 SPH_RS02285 SPH_RS02295 PF13817 SPH_RS02295 SPH_RS02300 PF13936 Helix-turn-helix domain SPH_RS02305 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS02310 PF00754 F5/8 type C domain SPH_RS02310 PF04650 SPH_RS02310 SPH_RS02310 PF12905 Endo-alpha-N-acetylgalactosaminidase SPH_RS02315 PF00905 Penicillin binding protein transpeptidase domain SPH_RS02315 PF00912 Transglycosylase SPH_RS02320 PF03838 Recombination protein U SPH_RS02325 PF06908 Protein of unknown function (DUF1273) SPH_RS02330 PF05103 DivIVA protein SPH_RS02335 PF01170 Putative RNA methylase family UPF0020 SPH_RS02335 PF02926 THUMP domain SPH_RS02345 PF00393 6-phosphogluconate dehydrogenase, C-terminal domain SPH_RS02345 PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase SPH_RS02350 PF00072 Response regulator receiver domain SPH_RS02350 PF00486 Transcriptional regulatory protein, C terminal SPH_RS02355 PF01473 Putative cell wall binding repeat SPH_RS02360 PF07690 Major Facilitator Superfamily SPH_RS02370 PF01473 Putative cell wall binding repeat SPH_RS02370 PF13340 SPH_RS02370 SPH_RS02375 PF00288 GHMP kinases N terminal domain SPH_RS02375 PF08544 GHMP kinases C terminal SPH_RS02380 PF00288 GHMP kinases N terminal domain SPH_RS02380 PF08544 GHMP kinases C terminal SPH_RS02385 PF00288 GHMP kinases N terminal domain SPH_RS02385 PF08544 GHMP kinases C terminal SPH_RS02390 PF01070 FMN-dependent dehydrogenase SPH_RS02395 PF09922 Cell wall-active antibiotics response protein (DUF2154) SPH_RS02400 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS02400 PF07730 Histidine kinase SPH_RS02405 PF00072 Response regulator receiver domain SPH_RS02405 PF00196 Bacterial regulatory proteins, luxR family SPH_RS02410 PF08713 DNA alkylation repair enzyme SPH_RS02415 PF08713 DNA alkylation repair enzyme SPH_RS02420 PF08713 DNA alkylation repair enzyme SPH_RS02430 PF00089 Trypsin SPH_RS02435 PF01473 Putative cell wall binding repeat SPH_RS02440 PF00665 Integrase core domain SPH_RS02440 PF13276 SPH_RS02440 SPH_RS02455 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS02455 PF02378 Phosphotransferase system, EIIC SPH_RS02460 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS02460 PF05043 Mga helix-turn-helix domain SPH_RS02460 PF08279 HTH domain SPH_RS02465 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS02470 PF01232 Mannitol dehydrogenase Rossmann domain SPH_RS02470 PF08125 Mannitol dehydrogenase C-terminal domain SPH_RS02485 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPH_RS02485 PF05697 Bacterial trigger factor protein (TF) SPH_RS02485 PF05698 Bacterial trigger factor protein (TF) C-terminus SPH_RS02490 PF13538 UvrD-like helicase C-terminal domain SPH_RS02490 PF13604 AAA domain SPH_RS02490 PF14490 Helix-hairpin-helix containing domain SPH_RS02495 PF00717 Peptidase S24-like SPH_RS02500 PF01351 Ribonuclease HII SPH_RS02500 PF11858 Domain of unknown function (DUF3378) SPH_RS02505 PF05164 Cell division protein ZapA SPH_RS02510 PF02674 SPH_RS02510 SPH_RS02515 PF00488 MutS domain V SPH_RS02515 PF01713 Smr domain SPH_RS02520 PF01235 SPH_RS02520 SPH_RS02525 PF02627 Carboxymuconolactone decarboxylase family SPH_RS02530 PF03595 Voltage-dependent anion channel SPH_RS02535 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS02535 PF02403 Seryl-tRNA synthetase N-terminal domain SPH_RS02540 PF06115 SPH_RS02540 SPH_RS02545 PF00696 Amino acid kinase family SPH_RS02545 PF13840 ACT domain SPH_RS02550 PF00378 Enoyl-CoA hydratase/isomerase family SPH_RS02555 PF01047 MarR family SPH_RS02560 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPH_RS02560 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPH_RS02565 PF00550 Phosphopantetheine attachment site SPH_RS02570 PF03060 Nitronate monooxygenase SPH_RS02575 PF00698 Acyl transferase domain SPH_RS02580 PF13561 Enoyl-(Acyl carrier protein) reductase SPH_RS02585 PF00109 Beta-ketoacyl synthase, N-terminal domain SPH_RS02585 PF02801 Beta-ketoacyl synthase, C-terminal domain SPH_RS02590 PF00364 Biotin-requiring enzyme SPH_RS02595 PF07977 FabA-like domain SPH_RS02600 PF00289 Carbamoyl-phosphate synthase L chain, N-terminal domain SPH_RS02600 PF02785 Biotin carboxylase C-terminal domain SPH_RS02600 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPH_RS02605 PF01039 Carboxyl transferase domain SPH_RS02610 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPH_RS02625 PF01029 NusB family SPH_RS02630 PF03780 SPH_RS02630 SPH_RS02635 PF01132 Elongation factor P (EF-P) OB domain SPH_RS02635 PF08207 Elongation factor P (EF-P) KOW-like domain SPH_RS02635 PF09285 Elongation factor P, C-terminal SPH_RS02640 PF02637 GatB domain SPH_RS02640 PF02934 GatB/GatE catalytic domain SPH_RS02645 PF01425 Amidase SPH_RS02650 PF02686 Glu-tRNAGln amidotransferase C subunit SPH_RS02655 PF00009 Elongation factor Tu GTP binding domain SPH_RS02655 PF03144 Elongation factor Tu domain 2 SPH_RS02655 PF16658 SPH_RS02655 SPH_RS02665 PF00830 Ribosomal L28 family SPH_RS02670 PF03780 SPH_RS02670 SPH_RS02675 PF02734 DAK2 domain SPH_RS02675 PF13684 Dihydroxyacetone kinase family SPH_RS02680 PF00205 Thiamine pyrophosphate enzyme, central domain SPH_RS02680 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPH_RS02680 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPH_RS02685 PF01842 ACT domain SPH_RS02685 PF10369 Small subunit of acetolactate synthase SPH_RS02690 PF01450 Acetohydroxy acid isomeroreductase, catalytic domain SPH_RS02690 PF07991 Acetohydroxy acid isomeroreductase, catalytic domain SPH_RS02705 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS02705 PF00585 C-terminal regulatory domain of Threonine dehydratase SPH_RS02715 PF00005 ABC transporter SPH_RS02720 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS02720 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS02725 PF09972 SPH_RS02725 SPH_RS02735 PF02371 SPH_RS02735 SPH_RS02745 PF02673 SPH_RS02745 SPH_RS02750 PF00817 impB/mucB/samB family SPH_RS02750 PF11798 IMS family HHH motif SPH_RS02750 PF11799 impB/mucB/samB family C-terminal domain SPH_RS02755 PF01228 Glycine radical SPH_RS02755 PF02901 Pyruvate formate lyase SPH_RS02760 PF01610 SPH_RS02760 SPH_RS02760 PF13542 SPH_RS02760 SPH_RS02760 PF14690 SPH_RS02760 SPH_RS02765 PF05043 Mga helix-turn-helix domain SPH_RS02765 PF08270 SPH_RS02765 SPH_RS02765 PF08280 M protein trans-acting positive regulator (MGA) HTH domain SPH_RS02770 PF05738 Cna protein B-type domain SPH_RS02770 PF13519 von Willebrand factor type A domain SPH_RS02775 PF00746 SPH_RS02775 SPH_RS02775 PF05738 Cna protein B-type domain SPH_RS02775 PF16555 SPH_RS02775 SPH_RS02775 PF16569 SPH_RS02775 SPH_RS02775 PF16570 SPH_RS02775 SPH_RS02780 PF05738 Cna protein B-type domain SPH_RS02785 PF04203 Sortase family SPH_RS02790 PF04203 Sortase family SPH_RS02795 PF04203 Sortase family SPH_RS02800 PF01610 SPH_RS02800 SPH_RS02805 PF01610 SPH_RS02805 SPH_RS02810 PF13542 SPH_RS02810 SPH_RS02810 PF14690 SPH_RS02810 SPH_RS02830 PF00480 ROK family SPH_RS02830 PF12802 MarR family SPH_RS02835 PF02378 Phosphotransferase system, EIIC SPH_RS02840 PF16126 SPH_RS02840 SPH_RS02845 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS02850 PF00232 Glycosyl hydrolase family 1 SPH_RS02855 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS02855 PF02378 Phosphotransferase system, EIIC SPH_RS02860 PF02386 Cation transport protein SPH_RS02865 PF02080 TrkA-C domain SPH_RS02865 PF02254 TrkA-N domain SPH_RS02870 PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase SPH_RS02875 PF07155 ECF-type riboflavin transporter, S component SPH_RS02885 PF00005 ABC transporter SPH_RS02885 PF12558 SPH_RS02885 SPH_RS02890 PF02361 Cobalt transport protein SPH_RS02895 PF00588 SpoU rRNA Methylase family SPH_RS02900 PF12822 Protein of unknown function (DUF3816) SPH_RS02905 PF01569 PAP2 superfamily SPH_RS02915 PF13302 Acetyltransferase (GNAT) domain SPH_RS02920 PF05066 HB1, ASXL, restriction endonuclease HTH domain SPH_RS02930 PF00117 Glutamine amidotransferase class-I SPH_RS02930 PF06418 CTP synthase N-terminus SPH_RS02935 PF01895 PhoU domain SPH_RS02935 PF02690 SPH_RS02935 SPH_RS02940 PF03644 Glycosyl hydrolase family 85 SPH_RS02940 PF07501 G5 domain SPH_RS02940 PF07523 Bacterial Ig-like domain (group 3) SPH_RS02945 PF00162 Phosphoglycerate kinase SPH_RS02950 PF06081 SPH_RS02950 SPH_RS02955 PF13411 MerR HTH family regulatory protein SPH_RS02960 PF00120 Glutamine synthetase, catalytic domain SPH_RS02960 PF03951 Glutamine synthetase, beta-Grasp domain SPH_RS02970 PF01420 Type I restriction modification DNA specificity domain SPH_RS02975 PF00589 Phage integrase family SPH_RS02980 PF01420 Type I restriction modification DNA specificity domain SPH_RS02985 PF01420 Type I restriction modification DNA specificity domain SPH_RS02990 PF02384 N-6 DNA Methylase SPH_RS02990 PF12161 HsdM N-terminal domain SPH_RS02995 PF00271 Helicase conserved C-terminal domain SPH_RS02995 PF04851 Type III restriction enzyme, res subunit SPH_RS02995 PF08463 SPH_RS02995 SPH_RS03010 PF01628 HrcA protein C terminal domain SPH_RS03010 PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding SPH_RS03015 PF01025 GrpE SPH_RS03020 PF00012 Hsp70 protein SPH_RS03030 PF00226 DnaJ domain SPH_RS03030 PF00684 DnaJ central domain SPH_RS03030 PF01556 DnaJ C terminal domain SPH_RS03040 PF01230 HIT domain SPH_RS03045 PF00005 ABC transporter SPH_RS03050 PF05975 SPH_RS03050 SPH_RS03060 PF04397 LytTr DNA-binding domain SPH_RS03065 PF00072 Response regulator receiver domain SPH_RS03065 PF04397 LytTr DNA-binding domain SPH_RS03070 PF14501 GHKL domain SPH_RS03075 PF03047 SPH_RS03075 SPH_RS03080 PF13437 HlyD family secretion protein SPH_RS03085 PF00005 ABC transporter SPH_RS03085 PF00664 ABC transporter transmembrane region SPH_RS03085 PF03412 Peptidase C39 family SPH_RS03090 PF10439 SPH_RS03090 SPH_RS03095 PF10439 SPH_RS03095 SPH_RS03100 PF10439 SPH_RS03100 SPH_RS03130 PF02517 CAAX protease self-immunity SPH_RS03140 PF02517 CAAX protease self-immunity SPH_RS03145 PF01636 Phosphotransferase enzyme family SPH_RS03150 PF02390 Putative methyltransferase SPH_RS03155 PF02576 Uncharacterised BCR, YhbC family COG0779 SPH_RS03160 PF08529 NusA N-terminal domain SPH_RS03160 PF13184 NusA-like KH domain SPH_RS03165 PF04296 Protein of unknown function (DUF448) SPH_RS03170 PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SPH_RS03175 PF00009 Elongation factor Tu GTP binding domain SPH_RS03175 PF04760 Translation initiation factor IF-2, N-terminal region SPH_RS03175 PF11987 Translation-initiation factor 2 SPH_RS03180 PF02033 Ribosome-binding factor A SPH_RS03205 PF08984 Domain of unknown function (DUF1858) SPH_RS03210 PF01814 Hemerythrin HHE cation binding domain SPH_RS03210 PF04282 SPH_RS03210 SPH_RS03210 PF13596 PAS domain SPH_RS03215 PF08930 Domain of unknown function (DUF1912) SPH_RS03225 PF01613 Flavin reductase like domain SPH_RS03230 PF13302 Acetyltransferase (GNAT) domain SPH_RS03235 PF13238 AAA domain SPH_RS03240 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS03240 PF08264 Anticodon-binding domain of tRNA SPH_RS03240 PF10458 Valyl tRNA synthetase tRNA binding arm SPH_RS03245 PF00145 C-5 cytosine-specific DNA methylase SPH_RS03255 PF02661 Fic/DOC family SPH_RS03265 PF04851 Type III restriction enzyme, res subunit SPH_RS03280 PF00874 PRD domain SPH_RS03280 PF03123 CAT RNA binding domain SPH_RS03285 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS03285 PF00367 phosphotransferase system, EIIB SPH_RS03285 PF02378 Phosphotransferase system, EIIC SPH_RS03290 PF00232 Glycosyl hydrolase family 1 SPH_RS03295 PF01409 tRNA synthetases class II core domain (F) SPH_RS03295 PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain SPH_RS03300 PF00583 Acetyltransferase (GNAT) family SPH_RS03305 PF01588 Putative tRNA binding domain SPH_RS03305 PF03147 Ferredoxin-fold anticodon binding domain SPH_RS03305 PF03483 B3/4 domain SPH_RS03305 PF03484 tRNA synthetase B5 domain SPH_RS03310 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS03315 PF13936 Helix-turn-helix domain SPH_RS03320 PF01381 Helix-turn-helix SPH_RS03325 PF01717 Cobalamin-independent synthase, Catalytic domain SPH_RS03325 PF08267 Cobalamin-independent synthase, N-terminal domain SPH_RS03330 PF02219 Methylenetetrahydrofolate reductase SPH_RS03335 PF00013 KH domain SPH_RS03335 PF00575 S1 RNA binding domain SPH_RS03335 PF01138 3' exoribonuclease family, domain 1 SPH_RS03335 PF03725 3' exoribonuclease family, domain 2 SPH_RS03335 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SPH_RS03340 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS03345 PF13673 Acetyltransferase (GNAT) domain SPH_RS03350 PF01406 tRNA synthetases class I (C) catalytic domain SPH_RS03350 PF09190 DALR domain SPH_RS03355 PF00636 Ribonuclease III domain SPH_RS03360 PF13556 PucR C-terminal helix-turn-helix domain SPH_RS03375 PF02687 SPH_RS03375 SPH_RS03380 PF00005 ABC transporter SPH_RS03385 PF02687 SPH_RS03385 SPH_RS03390 PF00072 Response regulator receiver domain SPH_RS03390 PF00486 Transcriptional regulatory protein, C terminal SPH_RS03395 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS03395 PF00672 HAMP domain SPH_RS03395 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS03400 PF01116 Fructose-bisphosphate aldolase class-II SPH_RS03405 PF00175 Oxidoreductase NAD-binding domain SPH_RS03405 PF01794 SPH_RS03405 SPH_RS03405 PF08022 SPH_RS03405 SPH_RS03410 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03415 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03420 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03425 PF00005 ABC transporter SPH_RS03430 PF01368 DHH family SPH_RS03430 PF02272 DHHA1 domain SPH_RS03430 PF10141 SPH_RS03430 SPH_RS03435 PF00753 Metallo-beta-lactamase superfamily SPH_RS03435 PF07521 RNA-metabolising metallo-beta-lactamase SPH_RS03440 PF00756 Putative esterase SPH_RS03445 PF02388 FemAB family SPH_RS03450 PF02388 FemAB family SPH_RS03455 PF00413 Matrixin SPH_RS03460 PF01541 GIY-YIG catalytic domain SPH_RS03460 PF02151 UvrB/uvrC motif SPH_RS03460 PF08459 UvrC Helix-hairpin-helix N-terminal SPH_RS03465 PF12850 Calcineurin-like phosphoesterase superfamily domain SPH_RS03470 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03475 PF00881 Nitroreductase family SPH_RS03480 PF01546 Peptidase family M20/M25/M40 SPH_RS03485 PF03167 Uracil DNA glycosylase superfamily SPH_RS03490 PF00581 Rhodanese-like domain SPH_RS03495 PF05525 SPH_RS03495 SPH_RS03500 PF05343 M42 glutamyl aminopeptidase SPH_RS03505 PF01230 HIT domain SPH_RS03510 PF02557 D-alanyl-D-alanine carboxypeptidase SPH_RS03515 PF00298 Ribosomal protein L11, RNA binding domain SPH_RS03515 PF03946 Ribosomal protein L11, N-terminal domain SPH_RS03520 PF00687 Ribosomal protein L1p/L10e family SPH_RS03530 PF02556 Preprotein translocase subunit SecB SPH_RS03540 PF00005 ABC transporter SPH_RS03545 PF06182 SPH_RS03545 SPH_RS03550 PF06182 SPH_RS03550 SPH_RS03570 PF00082 Subtilase family SPH_RS03570 PF00746 SPH_RS03570 SPH_RS03570 PF06280 Fn3-like domain (DUF1034) SPH_RS03575 PF13358 DDE superfamily endonuclease SPH_RS03585 PF03050 SPH_RS03585 SPH_RS03590 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS03595 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS03600 PF03611 SPH_RS03600 SPH_RS03605 PF00703 Glycosyl hydrolases family 2 SPH_RS03605 PF00746 SPH_RS03605 SPH_RS03605 PF02836 Glycosyl hydrolases family 2, TIM barrel domain SPH_RS03605 PF02837 Glycosyl hydrolases family 2, sugar binding domain SPH_RS03605 PF04650 SPH_RS03605 SPH_RS03605 PF07501 G5 domain SPH_RS03605 PF07532 SPH_RS03605 SPH_RS03605 PF16355 SPH_RS03605 SPH_RS03610 PF13751 SPH_RS03610 SPH_RS03620 PF11877 SPH_RS03620 SPH_RS03630 PF16199 SPH_RS03630 SPH_RS03635 PF06962 Putative rRNA methylase SPH_RS03650 PF03631 SPH_RS03650 SPH_RS03655 PF02683 SPH_RS03655 SPH_RS03660 PF00578 AhpC/TSA family SPH_RS03665 PF01625 Peptide methionine sulfoxide reductase SPH_RS03665 PF01641 SelR domain SPH_RS03670 PF00072 Response regulator receiver domain SPH_RS03670 PF12833 Helix-turn-helix domain SPH_RS03675 PF00672 HAMP domain SPH_RS03675 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS03675 PF02743 Cache domain SPH_RS03675 PF06580 SPH_RS03675 SPH_RS03680 PF04260 Protein of unknown function (DUF436) SPH_RS03685 PF00746 SPH_RS03685 SPH_RS03685 PF05342 SPH_RS03685 SPH_RS03685 PF07501 G5 domain SPH_RS03685 PF07580 SPH_RS03685 SPH_RS03690 PF00425 chorismate binding enzyme SPH_RS03690 PF01063 Aminotransferase class IV SPH_RS03695 PF12697 Alpha/beta hydrolase family SPH_RS03700 PF01473 Putative cell wall binding repeat SPH_RS03700 PF05901 SPH_RS03700 SPH_RS03705 PF00480 ROK family SPH_RS03710 PF00303 Thymidylate synthase SPH_RS03715 PF11240 SPH_RS03715 SPH_RS03720 PF01715 IPP transferase SPH_RS03725 PF01926 50S ribosome-binding GTPase SPH_RS03725 PF13167 SPH_RS03725 SPH_RS03725 PF16360 SPH_RS03725 SPH_RS03735 PF00753 Metallo-beta-lactamase superfamily SPH_RS03735 PF12706 Beta-lactamase superfamily domain SPH_RS03740 PF00106 short chain dehydrogenase SPH_RS03745 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPH_RS03745 PF03466 LysR substrate binding domain SPH_RS03750 PF06014 Bacterial protein of unknown function (DUF910) SPH_RS03755 PF00581 Rhodanese-like domain SPH_RS03765 PF00849 RNA pseudouridylate synthase SPH_RS03770 PF00009 Elongation factor Tu GTP binding domain SPH_RS03770 PF00679 Elongation factor G C-terminus SPH_RS03770 PF03144 Elongation factor Tu domain 2 SPH_RS03775 PF11364 SPH_RS03775 SPH_RS03780 PF09683 Bacteriocin (Lactococcin_972) SPH_RS03790 PF00005 ABC transporter SPH_RS03795 PF02875 Mur ligase family, glutamate ligase domain SPH_RS03795 PF08245 Mur ligase middle domain SPH_RS03800 PF03033 Glycosyltransferase family 28 N-terminal domain SPH_RS03800 PF04101 Glycosyltransferase family 28 C-terminal domain SPH_RS03805 PF08478 POTRA domain, FtsQ-type SPH_RS03810 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPH_RS03815 PF00156 Phosphoribosyl transferase domain SPH_RS03840 PF00005 ABC transporter SPH_RS03845 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS03860 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03870 PF00152 tRNA synthetases class II (D, K and N) SPH_RS03870 PF01336 OB-fold nucleic acid binding domain SPH_RS03880 PF03070 TENA/THI-4/PQQC family SPH_RS03885 PF02110 Hydroxyethylthiazole kinase family SPH_RS03890 PF02581 Thiamine monophosphate synthase/TENI SPH_RS03895 PF09819 SPH_RS03895 SPH_RS03900 PF00005 ABC transporter SPH_RS03910 PF03070 TENA/THI-4/PQQC family SPH_RS03915 PF09512 SPH_RS03915 SPH_RS03920 PF02110 Hydroxyethylthiazole kinase family SPH_RS03925 PF02581 Thiamine monophosphate synthase/TENI SPH_RS03930 PF08543 Phosphomethylpyrimidine kinase SPH_RS03935 PF03965 Penicillinase repressor SPH_RS03940 PF13473 Cupredoxin-like domain SPH_RS03945 PF00122 E1-E2 ATPase SPH_RS03945 PF00702 haloacid dehalogenase-like hydrolase SPH_RS03945 PF13473 Cupredoxin-like domain SPH_RS03950 PF00205 Thiamine pyrophosphate enzyme, central domain SPH_RS03950 PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain SPH_RS03950 PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain SPH_RS03965 PF13358 DDE superfamily endonuclease SPH_RS03970 PF13592 SPH_RS03970 SPH_RS03975 PF04854 SPH_RS03975 SPH_RS03980 PF01380 SIS domain SPH_RS03985 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS03990 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS03995 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS04005 PF13416 Bacterial extracellular solute-binding protein SPH_RS04010 PF12831 FAD dependent oxidoreductase SPH_RS04015 PF01230 HIT domain SPH_RS04020 PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS04025 PF04074 Domain of unknown function (DUF386) SPH_RS04035 PF00232 Glycosyl hydrolase family 1 SPH_RS04040 PF01238 Phosphomannose isomerase type I SPH_RS04045 PF00209 Sodium:neurotransmitter symporter family SPH_RS04055 PF01609 Transposase DDE domain SPH_RS04060 PF08002 Protein of unknown function (DUF1697) SPH_RS04065 PF03486 HI0933-like protein SPH_RS04070 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS04075 PF00440 Bacterial regulatory proteins, tetR family SPH_RS04080 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS04085 PF14681 Uracil phosphoribosyltransferase SPH_RS04090 PF00574 Clp protease SPH_RS04095 PF09902 SPH_RS04095 SPH_RS04100 PF13458 Periplasmic binding protein SPH_RS04105 PF02653 SPH_RS04105 SPH_RS04110 PF02653 SPH_RS04110 SPH_RS04115 PF00005 ABC transporter SPH_RS04115 PF12399 Branched-chain amino acid ATP-binding cassette transporter SPH_RS04120 PF00005 ABC transporter SPH_RS04125 PF00571 CBS domain SPH_RS04130 PF00472 RF-1 domain SPH_RS04130 PF03462 PCRF domain SPH_RS04135 PF00005 ABC transporter SPH_RS04140 PF02687 SPH_RS04140 SPH_RS04145 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS04145 PF00367 phosphotransferase system, EIIB SPH_RS04145 PF02378 Phosphotransferase system, EIIC SPH_RS04150 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS04155 PF00270 DEAD/DEAH box helicase SPH_RS04155 PF00271 Helicase conserved C-terminal domain SPH_RS04160 PF00438 S-adenosylmethionine synthetase, N-terminal domain SPH_RS04160 PF02772 S-adenosylmethionine synthetase, central domain SPH_RS04160 PF02773 S-adenosylmethionine synthetase, C-terminal domain SPH_RS04165 PF01180 Dihydroorotate dehydrogenase SPH_RS04170 PF06144 DNA polymerase III, delta subunit SPH_RS04175 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SPH_RS04175 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SPH_RS04180 PF06265 Protein of unknown function (DUF1027) SPH_RS04185 PF04055 Radical SAM superfamily SPH_RS04185 PF13394 4Fe-4S single cluster domain SPH_RS04190 PF04892 SPH_RS04190 SPH_RS04195 PF00005 ABC transporter SPH_RS04195 PF12848 ABC transporter SPH_RS04200 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPH_RS04215 PF00886 Ribosomal protein S16 SPH_RS04220 PF13083 KH domain SPH_RS04225 PF12697 Alpha/beta hydrolase family SPH_RS04230 PF01782 RimM N-terminal domain SPH_RS04230 PF05239 PRC-barrel domain SPH_RS04235 PF01746 tRNA (Guanine-1)-methyltransferase SPH_RS04240 PF03477 ATP cone domain SPH_RS04250 PF02229 Transcriptional Coactivator p15 (PC4) SPH_RS04260 PF02632 BioY family SPH_RS04265 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS04265 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS04270 PF16576 SPH_RS04270 SPH_RS04275 PF00005 ABC transporter SPH_RS04280 PF02687 SPH_RS04280 SPH_RS04280 PF12704 MacB-like periplasmic core domain SPH_RS04285 PF01588 Putative tRNA binding domain SPH_RS04285 PF09334 tRNA synthetases class I (M) SPH_RS04290 PF01610 SPH_RS04290 SPH_RS04290 PF13542 SPH_RS04290 SPH_RS04290 PF14690 SPH_RS04290 SPH_RS04300 PF03551 Transcriptional regulator PadR-like family SPH_RS04310 PF00248 Aldo/keto reductase family SPH_RS04315 PF11195 SPH_RS04315 SPH_RS04320 PF13561 Enoyl-(Acyl carrier protein) reductase SPH_RS04325 PF00293 NUDIX domain SPH_RS04330 PF02896 PEP-utilising enzyme, TIM barrel domain SPH_RS04335 PF04266 ASCH domain SPH_RS04340 PF01433 Peptidase family M1 SPH_RS04340 PF11838 ERAP1-like C-terminal domain SPH_RS04345 PF00072 Response regulator receiver domain SPH_RS04345 PF00486 Transcriptional regulatory protein, C terminal SPH_RS04350 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS04350 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04355 PF11674 SPH_RS04355 SPH_RS04360 PF01136 SPH_RS04360 SPH_RS04370 PF00270 DEAD/DEAH box helicase SPH_RS04370 PF00929 Exonuclease SPH_RS04370 PF13307 Helicase C-terminal domain SPH_RS04375 PF01098 SPH_RS04375 SPH_RS04380 PF01965 DJ-1/PfpI family SPH_RS04385 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS04390 PF00204 DNA gyrase B SPH_RS04390 PF00986 DNA gyrase B subunit, carboxyl terminus SPH_RS04390 PF01751 Toprim domain SPH_RS04390 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04395 PF06160 SPH_RS04395 SPH_RS04400 PF13592 SPH_RS04400 SPH_RS04405 PF13358 DDE superfamily endonuclease SPH_RS04410 PF05717 SPH_RS04410 SPH_RS04415 PF00665 Integrase core domain SPH_RS04430 PF08860 Domain of unknown function (DUF1827) SPH_RS04435 PF00293 NUDIX domain SPH_RS04440 PF01710 Transposase SPH_RS04445 PF13358 DDE superfamily endonuclease SPH_RS04450 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS04450 PF02151 UvrB/uvrC motif SPH_RS04450 PF07724 AAA domain (Cdc48 subfamily) SPH_RS04450 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS04455 PF08796 Protein of unknown function (DUF1797) SPH_RS04460 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS04465 PF00005 ABC transporter SPH_RS04470 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPH_RS04470 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPH_RS04475 PF01256 Carbohydrate kinase SPH_RS04480 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SPH_RS04485 PF01676 Metalloenzyme superfamily SPH_RS04490 PF08002 Protein of unknown function (DUF1697) SPH_RS04495 PF01048 Phosphorylase superfamily SPH_RS04500 PF01764 Lipase (class 3) SPH_RS04505 PF00754 F5/8 type C domain SPH_RS04510 PF01289 Thiol-activated cytolysin SPH_RS04515 PF01048 Phosphorylase superfamily SPH_RS04525 PF01649 Ribosomal protein S20 SPH_RS04530 PF00485 Phosphoribulokinase / Uridine kinase family SPH_RS04540 PF05175 Methyltransferase small domain SPH_RS04545 PF00591 Glycosyl transferase family, a/b domain SPH_RS04545 PF02885 Glycosyl transferase family, helical bundle domain SPH_RS04545 PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain SPH_RS04550 PF01791 DeoC/LacD family aldolase SPH_RS04555 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS04560 PF02608 Basic membrane protein SPH_RS04565 PF00005 ABC transporter SPH_RS04570 PF02653 SPH_RS04570 SPH_RS04575 PF02653 SPH_RS04575 SPH_RS04590 PF00665 Integrase core domain SPH_RS04590 PF13276 SPH_RS04590 SPH_RS04595 PF02660 SPH_RS04595 SPH_RS04600 PF00204 DNA gyrase B SPH_RS04600 PF00986 DNA gyrase B subunit, carboxyl terminus SPH_RS04600 PF01751 Toprim domain SPH_RS04600 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS04610 PF00521 DNA gyrase/topoisomerase IV, subunit A SPH_RS04610 PF03989 DNA gyrase C-terminal domain, beta-propeller SPH_RS04615 PF01063 Aminotransferase class IV SPH_RS04625 PF06149 SPH_RS04625 SPH_RS04630 PF06166 SPH_RS04630 SPH_RS04635 PF01470 Pyroglutamyl peptidase SPH_RS04640 PF11184 SPH_RS04640 SPH_RS04655 PF00575 S1 RNA binding domain SPH_RS04660 PF01610 SPH_RS04660 SPH_RS04665 PF01610 SPH_RS04665 SPH_RS04670 PF13542 SPH_RS04670 SPH_RS04670 PF14690 SPH_RS04670 SPH_RS04675 PF13185 GAF domain SPH_RS04680 PF12169 DNA polymerase III subunits gamma and tau domain III SPH_RS04680 PF13177 DNA polymerase III, delta subunit SPH_RS04685 PF11676 SPH_RS04685 SPH_RS04690 PF00005 ABC transporter SPH_RS04695 PF01458 Uncharacterized protein family (UPF0051) SPH_RS04700 PF00266 Aminotransferase class-V SPH_RS04705 PF01592 NifU-like N terminal domain SPH_RS04710 PF01458 Uncharacterized protein family (UPF0051) SPH_RS04720 PF00768 D-alanyl-D-alanine carboxypeptidase SPH_RS04720 PF07943 Penicillin-binding protein 5, C-terminal domain SPH_RS04725 PF01594 SPH_RS04725 SPH_RS04735 PF00455 SPH_RS04735 SPH_RS04735 PF08220 DeoR-like helix-turn-helix domain SPH_RS04740 PF00294 pfkB family carbohydrate kinase SPH_RS04745 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS04745 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS04745 PF02378 Phosphotransferase system, EIIC SPH_RS04750 PF01580 FtsK/SpoIIIE family SPH_RS04750 PF09397 Ftsk gamma domain SPH_RS04760 PF00266 Aminotransferase class-V SPH_RS04765 PF02568 Thiamine biosynthesis protein (ThiI) SPH_RS04765 PF02926 THUMP domain SPH_RS04770 PF00756 Putative esterase SPH_RS04780 PF00756 Putative esterase SPH_RS04785 PF13535 ATP-grasp domain SPH_RS04795 PF02384 N-6 DNA Methylase SPH_RS04795 PF12161 HsdM N-terminal domain SPH_RS04800 PF01420 Type I restriction modification DNA specificity domain SPH_RS04810 PF02661 Fic/DOC family SPH_RS04815 PF00589 Phage integrase family SPH_RS04815 PF13495 Phage integrase, N-terminal SAM-like domain SPH_RS04820 PF01420 Type I restriction modification DNA specificity domain SPH_RS04825 PF00271 Helicase conserved C-terminal domain SPH_RS04825 PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) SPH_RS04825 PF04851 Type III restriction enzyme, res subunit SPH_RS04825 PF08463 SPH_RS04825 SPH_RS04825 PF13643 SPH_RS04825 SPH_RS04835 PF01316 Arginine repressor, DNA binding domain SPH_RS04835 PF02863 Arginine repressor, C-terminal domain SPH_RS04840 PF02129 X-Pro dipeptidyl-peptidase (S15 family) SPH_RS04840 PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SPH_RS04840 PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal SPH_RS04845 PF01336 OB-fold nucleic acid binding domain SPH_RS04845 PF02811 PHP domain SPH_RS04845 PF07733 Bacterial DNA polymerase III alpha subunit SPH_RS04845 PF14579 Helix-hairpin-helix motif SPH_RS04850 PF00365 Phosphofructokinase SPH_RS04855 PF00224 Pyruvate kinase, barrel domain SPH_RS04855 PF02887 Pyruvate kinase, alpha/beta domain SPH_RS04860 PF00589 Phage integrase family SPH_RS04870 PF14133 SPH_RS04870 SPH_RS04880 PF13613 SPH_RS04880 SPH_RS04895 PF09323 SPH_RS04895 SPH_RS04900 PF03773 SPH_RS04900 SPH_RS04910 PF00575 S1 RNA binding domain SPH_RS04910 PF09371 Tex-like protein N-terminal domain SPH_RS04910 PF12836 Helix-hairpin-helix motif SPH_RS04910 PF16921 SPH_RS04910 SPH_RS04915 PF10263 SPH_RS04915 SPH_RS04920 PF04024 SPH_RS04920 SPH_RS04935 PF00005 ABC transporter SPH_RS04940 PF02687 SPH_RS04940 SPH_RS04945 PF01988 SPH_RS04945 SPH_RS04955 PF01276 Orn/Lys/Arg decarboxylase, major domain SPH_RS04955 PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain SPH_RS04970 PF01564 Spermine/spermidine synthase SPH_RS04975 PF03435 Saccharopine dehydrogenase SPH_RS04975 PF16653 SPH_RS04975 SPH_RS04980 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPH_RS04985 PF04371 Porphyromonas-type peptidyl-arginine deiminase SPH_RS04990 PF00795 Carbon-nitrogen hydrolase SPH_RS04995 PF08282 haloacid dehalogenase-like hydrolase SPH_RS05005 PF02517 CAAX protease self-immunity SPH_RS05015 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPH_RS05015 PF03466 LysR substrate binding domain SPH_RS05020 PF01252 SPH_RS05020 SPH_RS05025 PF00849 RNA pseudouridylate synthase SPH_RS05025 PF01479 S4 domain SPH_RS05030 PF00753 Metallo-beta-lactamase superfamily SPH_RS05030 PF01473 Putative cell wall binding repeat SPH_RS05035 PF00696 Amino acid kinase family SPH_RS05035 PF01472 PUA domain SPH_RS05040 PF00171 Aldehyde dehydrogenase family SPH_RS05045 PF03807 NADP oxidoreductase coenzyme F420-dependent SPH_RS05045 PF14748 Pyrroline-5-carboxylate reductase dimerisation SPH_RS05050 PF02223 Thymidylate kinase SPH_RS05055 PF13177 DNA polymerase III, delta subunit SPH_RS05060 PF06156 SPH_RS05060 SPH_RS05065 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPH_RS05070 PF01134 Glucose inhibited division protein A SPH_RS05075 PF00696 Amino acid kinase family SPH_RS05080 PF01765 Ribosome recycling factor SPH_RS05085 PF13509 S1 domain SPH_RS05090 PF06855 Protein of unknown function (DUF1250) SPH_RS05095 PF02562 PhoH-like protein SPH_RS05100 PF13302 Acetyltransferase (GNAT) domain SPH_RS05105 PF10531 SLBB domain SPH_RS05105 PF12836 Helix-hairpin-helix motif SPH_RS05110 PF03772 SPH_RS05110 SPH_RS05110 PF13567 SPH_RS05110 SPH_RS05120 PF00005 ABC transporter SPH_RS05130 PF00707 Translation initiation factor IF-3, C-terminal domain SPH_RS05130 PF05198 Translation initiation factor IF-3, N-terminal domain SPH_RS05135 PF01632 Ribosomal protein L35 SPH_RS05140 PF00453 Ribosomal protein L20 SPH_RS05145 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPH_RS05150 PF00175 Oxidoreductase NAD-binding domain SPH_RS05150 PF00970 Oxidoreductase FAD-binding domain SPH_RS05150 PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B SPH_RS05155 PF01180 Dihydroorotate dehydrogenase SPH_RS05160 PF01473 Putative cell wall binding repeat SPH_RS05160 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPH_RS05165 PF05670 SPH_RS05165 SPH_RS05165 PF05833 Fibronectin-binding protein A N-terminus (FbpA) SPH_RS05170 PF02130 Uncharacterized protein family UPF0054 SPH_RS05175 PF01219 Prokaryotic diacylglycerol kinase SPH_RS05180 PF01926 50S ribosome-binding GTPase SPH_RS05180 PF07650 KH domain SPH_RS05185 PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain SPH_RS05185 PF06827 Zinc finger found in FPG and IleRS SPH_RS05185 PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain SPH_RS05190 PF01121 Dephospho-CoA kinase SPH_RS05195 PF07690 Major Facilitator Superfamily SPH_RS05200 PF00471 Ribosomal protein L33 SPH_RS05205 PF03840 Preprotein translocase SecG subunit SPH_RS05210 PF00575 S1 RNA binding domain SPH_RS05210 PF00773 RNB domain SPH_RS05210 PF08206 Ribonuclease B OB domain SPH_RS05215 PF01668 SmpB protein SPH_RS05220 PF03848 Tellurite resistance protein TehB SPH_RS05220 PF09313 Domain of unknown function (DUF1971) SPH_RS05225 PF06054 SPH_RS05225 SPH_RS05230 PF01432 Peptidase family M3 SPH_RS05230 PF08439 Oligopeptidase F SPH_RS05235 PF01596 O-methyltransferase SPH_RS05240 PF13145 PPIC-type PPIASE domain SPH_RS05245 PF13333 SPH_RS05245 SPH_RS05255 PF00300 Histidine phosphatase superfamily (branch 1) SPH_RS05260 PF04073 Aminoacyl-tRNA editing domain SPH_RS05265 PF04018 SPH_RS05265 SPH_RS05270 PF01183 Glycosyl hydrolases family 25 SPH_RS05275 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS05275 PF00483 Nucleotidyl transferase SPH_RS05275 PF14602 Hexapeptide repeat of succinyl-transferase SPH_RS05280 PF00293 NUDIX domain SPH_RS05290 PF01048 Phosphorylase superfamily SPH_RS05295 PF04394 SPH_RS05295 SPH_RS05295 PF13412 Winged helix-turn-helix DNA-binding SPH_RS05300 PF00929 Exonuclease SPH_RS05305 PF03009 Glycerophosphoryl diester phosphodiesterase family SPH_RS05305 PF10110 SPH_RS05305 SPH_RS05310 PF01710 Transposase SPH_RS05330 PF02683 SPH_RS05330 SPH_RS05335 PF00578 AhpC/TSA family SPH_RS05340 PF13520 Amino acid permease SPH_RS05345 PF01297 Periplasmic solute binding protein family SPH_RS05350 PF04270 Streptococcal histidine triad protein SPH_RS05350 PF16645 SPH_RS05350 SPH_RS05355 PF04270 Streptococcal histidine triad protein SPH_RS05360 PF04270 Streptococcal histidine triad protein SPH_RS05365 PF04270 Streptococcal histidine triad protein SPH_RS05380 PF01546 Peptidase family M20/M25/M40 SPH_RS05380 PF07687 Peptidase dimerisation domain SPH_RS05385 PF00762 Ferrochelatase SPH_RS05390 PF01741 Large-conductance mechanosensitive channel, MscL SPH_RS05395 PF04138 SPH_RS05395 SPH_RS05400 PF06177 SPH_RS05400 SPH_RS05410 PF01118 Semialdehyde dehydrogenase, NAD binding domain SPH_RS05410 PF02774 Semialdehyde dehydrogenase, dimerisation domain SPH_RS05415 PF00701 Dihydrodipicolinate synthetase family SPH_RS05420 PF01926 50S ribosome-binding GTPase SPH_RS05420 PF10396 GTP-binding protein TrmE N-terminus SPH_RS05420 PF12631 Catalytic cysteine-containing C-terminus of GTPase, MnmE SPH_RS05425 PF01361 Tautomerase enzyme SPH_RS05430 PF00265 Thymidine kinase SPH_RS05435 PF00583 Acetyltransferase (GNAT) family SPH_RS05440 PF00472 RF-1 domain SPH_RS05440 PF03462 PCRF domain SPH_RS05445 PF05175 Methyltransferase small domain SPH_RS05450 PF01300 Telomere recombination SPH_RS05455 PF00583 Acetyltransferase (GNAT) family SPH_RS05460 PF00464 Serine hydroxymethyltransferase SPH_RS05465 PF04245 SPH_RS05465 SPH_RS05470 PF13702 Lysozyme-like SPH_RS05475 PF06207 SPH_RS05475 SPH_RS05480 PF05958 tRNA (Uracil-5-)-methyltransferase SPH_RS05490 PF13443 Cro/C1-type HTH DNA-binding domain SPH_RS05500 PF01497 Periplasmic binding protein SPH_RS05505 PF01032 FecCD transport family SPH_RS05510 PF01032 FecCD transport family SPH_RS05515 PF00005 ABC transporter SPH_RS05535 PF00239 Resolvase, N terminal domain SPH_RS05535 PF07508 Recombinase SPH_RS05535 PF13408 Recombinase zinc beta ribbon domain SPH_RS05550 PF14243 SPH_RS05550 SPH_RS05555 PF03747 ADP-ribosylglycohydrolase SPH_RS05560 PF00781 Diacylglycerol kinase catalytic domain SPH_RS05565 PF00128 Alpha amylase, catalytic domain SPH_RS05565 PF02903 Alpha amylase, N-terminal ig-like domain SPH_RS05580 PF00583 Acetyltransferase (GNAT) family SPH_RS05605 PF01098 SPH_RS05605 SPH_RS05610 PF00311 Phosphoenolpyruvate carboxylase SPH_RS05615 PF04392 ABC transporter substrate binding protein SPH_RS05620 PF02653 SPH_RS05620 SPH_RS05625 PF00005 ABC transporter SPH_RS05630 PF01807 CHC2 zinc finger SPH_RS05630 PF08275 DNA primase catalytic core, N-terminal domain SPH_RS05630 PF13662 Toprim domain SPH_RS05635 PF00140 Sigma-70 factor, region 1 SPH_RS05635 PF03979 Sigma-70 factor, region 1 SPH_RS05635 PF04539 Sigma-70 region 3 SPH_RS05635 PF04542 Sigma-70 region 2 SPH_RS05635 PF04545 Sigma-70, region 4 SPH_RS05640 PF01883 Domain of unknown function DUF59 SPH_RS05645 PF00534 Glycosyl transferases group 1 SPH_RS05650 PF00534 Glycosyl transferases group 1 SPH_RS05650 PF13439 Glycosyltransferase Family 4 SPH_RS05655 PF04024 SPH_RS05655 SPH_RS05660 PF13253 SPH_RS05660 SPH_RS05665 PF01018 GTP1/OBG SPH_RS05665 PF01926 50S ribosome-binding GTPase SPH_RS05665 PF09269 Domain of unknown function (DUF1967) SPH_RS05675 PF01610 SPH_RS05675 SPH_RS05680 PF01610 SPH_RS05680 SPH_RS05680 PF13542 SPH_RS05680 SPH_RS05685 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS05690 PF13302 Acetyltransferase (GNAT) domain SPH_RS05695 PF00392 Bacterial regulatory proteins, gntR family SPH_RS05695 PF00571 CBS domain SPH_RS05695 PF03061 Thioesterase superfamily SPH_RS05695 PF07085 DRTGG domain SPH_RS05700 PF00557 Metallopeptidase family M24 SPH_RS05710 PF13613 SPH_RS05710 SPH_RS05715 PF01609 Transposase DDE domain SPH_RS05720 PF00580 UvrD/REP helicase N-terminal domain SPH_RS05720 PF13361 UvrD-like helicase C-terminal domain SPH_RS05725 PF04002 RadC-like JAB domain SPH_RS05730 PF07722 Peptidase C26 SPH_RS05735 PF02629 CoA binding domain SPH_RS05735 PF06971 Putative DNA-binding protein N-terminus SPH_RS05740 PF15507 Domain of unknown function (DUF4649) SPH_RS05745 PF08866 Putative amino acid metabolism SPH_RS05750 PF00266 Aminotransferase class-V SPH_RS05755 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPH_RS05755 PF14572 Phosphoribosyl synthetase-associated domain SPH_RS05760 PF01928 CYTH domain SPH_RS05765 PF04607 Region found in RelA / SpoT proteins SPH_RS05770 PF01513 ATP-NAD kinase SPH_RS05775 PF00849 RNA pseudouridylate synthase SPH_RS05780 PF01515 Phosphate acetyl/butaryl transferase SPH_RS05785 PF01610 SPH_RS05785 SPH_RS05790 PF01610 SPH_RS05790 SPH_RS05795 PF13542 SPH_RS05795 SPH_RS05795 PF14690 SPH_RS05795 SPH_RS05800 PF02575 YbaB/EbfC DNA-binding family SPH_RS05805 PF06912 SPH_RS05805 SPH_RS05810 PF00829 Ribosomal prokaryotic L21 protein SPH_RS05815 PF04327 Protein of unknown function (DUF464) SPH_RS05820 PF01016 Ribosomal L27 protein SPH_RS05830 PF01687 Riboflavin kinase SPH_RS05830 PF06574 FAD synthetase SPH_RS05835 PF02588 SPH_RS05835 SPH_RS05835 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPH_RS05840 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS05845 PF00216 Bacterial DNA-binding protein SPH_RS05850 PF00005 ABC transporter SPH_RS05850 PF12848 ABC transporter SPH_RS05850 PF16326 SPH_RS05850 SPH_RS05855 PF12844 Helix-turn-helix domain SPH_RS05860 PF07690 Major Facilitator Superfamily SPH_RS05865 PF00533 BRCA1 C Terminus (BRCT) domain SPH_RS05865 PF01653 NAD-dependent DNA ligase adenylation domain SPH_RS05865 PF03119 NAD-dependent DNA ligase C4 zinc finger domain SPH_RS05865 PF03120 NAD-dependent DNA ligase OB-fold domain SPH_RS05865 PF12826 Helix-hairpin-helix motif SPH_RS05865 PF14520 Helix-hairpin-helix domain SPH_RS05870 PF00128 Alpha amylase, catalytic domain SPH_RS05870 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS05870 PF03714 Bacterial pullanase-associated domain SPH_RS05880 PF00171 Aldehyde dehydrogenase family SPH_RS05885 PF00128 Alpha amylase, catalytic domain SPH_RS05885 PF02806 Alpha amylase, C-terminal all-beta domain SPH_RS05885 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPH_RS05890 PF00483 Nucleotidyl transferase SPH_RS05895 PF00483 Nucleotidyl transferase SPH_RS05900 PF00534 Glycosyl transferases group 1 SPH_RS05900 PF08323 Starch synthase catalytic domain SPH_RS05905 PF12710 haloacid dehalogenase-like hydrolase SPH_RS05910 PF08282 haloacid dehalogenase-like hydrolase SPH_RS05915 PF02595 Glycerate kinase family SPH_RS05920 PF07997 Protein of unknown function (DUF1694) SPH_RS05925 PF00113 Enolase, C-terminal TIM barrel domain SPH_RS05925 PF03952 Enolase, N-terminal domain SPH_RS05930 PF13358 DDE superfamily endonuclease SPH_RS05935 PF01710 Transposase SPH_RS05940 PF04257 Exodeoxyribonuclease V, gamma subunit SPH_RS05940 PF12705 PD-(D/E)XK nuclease superfamily SPH_RS05945 PF00580 UvrD/REP helicase N-terminal domain SPH_RS05945 PF12705 PD-(D/E)XK nuclease superfamily SPH_RS05945 PF13361 UvrD-like helicase C-terminal domain SPH_RS05955 PF00746 SPH_RS05955 SPH_RS05955 PF04650 SPH_RS05955 SPH_RS05955 PF05342 SPH_RS05955 SPH_RS05955 PF07501 G5 domain SPH_RS05955 PF07580 SPH_RS05955 SPH_RS05955 PF07581 SPH_RS05955 SPH_RS05960 PF01610 SPH_RS05960 SPH_RS05960 PF13542 SPH_RS05960 SPH_RS05960 PF14690 SPH_RS05960 SPH_RS05965 PF06970 Replication initiator protein A (RepA) N-terminus SPH_RS05970 PF00145 C-5 cytosine-specific DNA methylase SPH_RS05990 PF02517 CAAX protease self-immunity SPH_RS05995 PF13338 SPH_RS05995 SPH_RS06000 PF08843 Nucleotidyl transferase of unknown function (DUF1814) SPH_RS06015 PF02534 Type IV secretory system Conjugative DNA transfer SPH_RS06025 PF04610 SPH_RS06025 SPH_RS06030 PF12666 SPH_RS06030 SPH_RS06040 PF05257 CHAP domain SPH_RS06090 PF13154 SPH_RS06090 SPH_RS06090 PF13155 Toprim-like SPH_RS06110 PF01381 Helix-turn-helix SPH_RS06115 PF06414 Zeta toxin SPH_RS06130 PF00302 Chloramphenicol acetyltransferase SPH_RS06135 PF01446 SPH_RS06135 SPH_RS06145 PF00128 Alpha amylase, catalytic domain SPH_RS06145 PF02903 Alpha amylase, N-terminal ig-like domain SPH_RS06160 PF01926 50S ribosome-binding GTPase SPH_RS06165 PF01351 Ribonuclease HII SPH_RS06170 PF00654 Voltage gated chloride channel SPH_RS06170 PF02080 TrkA-C domain SPH_RS06175 PF00589 Phage integrase family SPH_RS06185 PF00665 Integrase core domain SPH_RS06185 PF13276 SPH_RS06185 SPH_RS06190 PF01554 MatE SPH_RS06200 PF01979 Amidohydrolase family SPH_RS06205 PF00293 NUDIX domain SPH_RS06210 PF03167 Uracil DNA glycosylase superfamily SPH_RS06215 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS06225 PF00005 ABC transporter SPH_RS06225 PF00664 ABC transporter transmembrane region SPH_RS06230 PF00005 ABC transporter SPH_RS06235 PF12730 SPH_RS06235 SPH_RS06240 PF00440 Bacterial regulatory proteins, tetR family SPH_RS06245 PF03610 PTS system fructose IIA component SPH_RS06250 PF02734 DAK2 domain SPH_RS06255 PF02733 Dak1 domain SPH_RS06260 PF00440 Bacterial regulatory proteins, tetR family SPH_RS06265 PF02733 Dak1 domain SPH_RS06270 PF08020 Protein of unknown function (DUF1706) SPH_RS06275 PF03692 SPH_RS06275 SPH_RS06280 PF00391 PEP-utilising enzyme, mobile domain SPH_RS06280 PF02896 PEP-utilising enzyme, TIM barrel domain SPH_RS06280 PF05524 PEP-utilising enzyme, N-terminal SPH_RS06285 PF00381 PTS HPr component phosphorylation site SPH_RS06290 PF00462 Glutaredoxin SPH_RS06295 PF00317 Ribonucleotide reductase, all-alpha domain SPH_RS06295 PF02867 Ribonucleotide reductase, barrel domain SPH_RS06295 PF08343 Ribonucleotide reductase N-terminal SPH_RS06300 PF00268 Ribonucleotide reductase, small chain SPH_RS06305 PF00455 SPH_RS06305 SPH_RS06305 PF08220 DeoR-like helix-turn-helix domain SPH_RS06310 PF13024 SPH_RS06310 SPH_RS06315 PF00232 Glycosyl hydrolase family 1 SPH_RS06320 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS06320 PF02378 Phosphotransferase system, EIIC SPH_RS06325 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS06330 PF00874 PRD domain SPH_RS06330 PF03123 CAT RNA binding domain SPH_RS06335 PF01791 DeoC/LacD family aldolase SPH_RS06340 PF00294 pfkB family carbohydrate kinase SPH_RS06345 PF02502 Ribose/Galactose Isomerase SPH_RS06350 PF02502 Ribose/Galactose Isomerase SPH_RS06360 PF13359 SPH_RS06360 SPH_RS06370 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS06385 PF00009 Elongation factor Tu GTP binding domain SPH_RS06385 PF00679 Elongation factor G C-terminus SPH_RS06385 PF03144 Elongation factor Tu domain 2 SPH_RS06385 PF06421 GTP-binding protein LepA C-terminus SPH_RS06390 PF00149 Calcineurin-like phosphoesterase SPH_RS06395 PF02463 RecF/RecN/SMC N terminal domain SPH_RS06400 PF01316 Arginine repressor, DNA binding domain SPH_RS06400 PF02863 Arginine repressor, C-terminal domain SPH_RS06405 PF01728 FtsJ-like methyltransferase SPH_RS06410 PF00348 Polyprenyl synthetase SPH_RS06415 PF02609 Exonuclease VII small subunit SPH_RS06420 PF02601 SPH_RS06420 SPH_RS06420 PF13742 SPH_RS06420 SPH_RS06425 PF00485 Phosphoribulokinase / Uridine kinase family SPH_RS06430 PF08951 Enterocin A Immunity SPH_RS06440 PF01509 TruB family pseudouridylate synthase (N terminal domain) SPH_RS06440 PF16198 SPH_RS06440 SPH_RS06445 PF09903 SPH_RS06445 SPH_RS06455 PF01226 Formate/nitrite transporter SPH_RS06460 PF04203 Sortase family SPH_RS06465 PF00521 DNA gyrase/topoisomerase IV, subunit A SPH_RS06465 PF03989 DNA gyrase C-terminal domain, beta-propeller SPH_RS06470 PF00056 lactate/malate dehydrogenase, NAD binding domain SPH_RS06470 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain SPH_RS06475 PF07885 Ion channel SPH_RS06480 PF05016 Plasmid stabilisation system protein SPH_RS06490 PF00753 Metallo-beta-lactamase superfamily SPH_RS06495 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS06495 PF00989 PAS fold SPH_RS06495 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS06500 PF00072 Response regulator receiver domain SPH_RS06500 PF00486 Transcriptional regulatory protein, C terminal SPH_RS06505 PF00633 Helix-hairpin-helix motif SPH_RS06505 PF00730 HhH-GPD superfamily base excision DNA repair protein SPH_RS06505 PF14815 NUDIX domain SPH_RS06510 PF01268 Formate--tetrahydrofolate ligase SPH_RS06515 PF04127 DNA / pantothenate metabolism flavoprotein SPH_RS06520 PF02441 Flavoprotein SPH_RS06525 PF12822 Protein of unknown function (DUF3816) SPH_RS06530 PF07155 ECF-type riboflavin transporter, S component SPH_RS06535 PF02829 3H domain SPH_RS06535 PF08279 HTH domain SPH_RS06540 PF00293 NUDIX domain SPH_RS06545 PF00583 Acetyltransferase (GNAT) family SPH_RS06550 PF13302 Acetyltransferase (GNAT) domain SPH_RS06555 PF00271 Helicase conserved C-terminal domain SPH_RS06555 PF02151 UvrB/uvrC motif SPH_RS06555 PF04851 Type III restriction enzyme, res subunit SPH_RS06555 PF12344 Ultra-violet resistance protein B SPH_RS06565 PF02517 CAAX protease self-immunity SPH_RS06570 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS06570 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS06575 PF00005 ABC transporter SPH_RS06580 PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain SPH_RS06580 PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain SPH_RS06585 PF00448 SRP54-type protein, GTPase domain SPH_RS06585 PF02881 SRP54-type protein, helical bundle domain SPH_RS06590 PF08282 haloacid dehalogenase-like hydrolase SPH_RS06595 PF08282 haloacid dehalogenase-like hydrolase SPH_RS06600 PF02463 RecF/RecN/SMC N terminal domain SPH_RS06600 PF06470 SMC proteins Flexible Hinge Domain SPH_RS06605 PF00035 Double-stranded RNA binding motif SPH_RS06605 PF14622 Ribonuclease-III-like SPH_RS06615 PF00478 IMP dehydrogenase / GMP reductase domain SPH_RS06620 PF10117 SPH_RS06620 SPH_RS06625 PF07728 AAA domain (dynein-related subfamily) SPH_RS06640 PF00694 Aconitase C-terminal domain SPH_RS06645 PF06961 SPH_RS06645 SPH_RS06650 PF00180 Isocitrate/isopropylmalate dehydrogenase SPH_RS06655 PF00682 HMGL-like SPH_RS06655 PF08502 LeuA allosteric (dimerisation) domain SPH_RS06660 PF04237 YjbR SPH_RS06665 PF03932 CutC family SPH_RS06670 PF04304 SPH_RS06670 SPH_RS06675 PF01131 DNA topoisomerase SPH_RS06675 PF01396 SPH_RS06675 SPH_RS06675 PF01751 Toprim domain SPH_RS06685 PF02481 DNA recombination-mediator protein A SPH_RS06690 PF12804 MobA-like NTP transferase domain SPH_RS06695 PF00892 EamA-like transporter family SPH_RS06700 PF01633 Choline/ethanolamine kinase SPH_RS06705 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS06710 PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase SPH_RS06715 PF01943 SPH_RS06715 SPH_RS06720 PF04991 SPH_RS06720 SPH_RS06725 PF04991 SPH_RS06725 SPH_RS06730 PF02142 MGS-like domain SPH_RS06730 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPH_RS06730 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPH_RS06735 PF00117 Glutamine amidotransferase class-I SPH_RS06735 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SPH_RS06740 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPH_RS06740 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPH_RS06745 PF00156 Phosphoribosyl transferase domain SPH_RS06750 PF00633 Helix-hairpin-helix motif SPH_RS06750 PF00730 HhH-GPD superfamily base excision DNA repair protein SPH_RS06755 PF02620 SPH_RS06755 SPH_RS06765 PF00005 ABC transporter SPH_RS06770 PF01435 Peptidase family M48 SPH_RS06775 PF04011 LemA family SPH_RS06780 PF02527 rRNA small subunit methyltransferase G SPH_RS06785 PF00589 Phage integrase family SPH_RS06785 PF02920 DNA binding domain of tn916 integrase SPH_RS06790 PF09035 Excisionase from transposon Tn916 SPH_RS06795 PF12645 SPH_RS06795 SPH_RS06800 PF08281 Sigma-70, region 4 SPH_RS06805 PF01381 Helix-turn-helix SPH_RS06815 PF00009 Elongation factor Tu GTP binding domain SPH_RS06815 PF00679 Elongation factor G C-terminus SPH_RS06815 PF03764 Elongation factor G, domain IV SPH_RS06815 PF14492 Elongation Factor G, domain II SPH_RS06820 PF12642 Conjugative transposon protein TcpC SPH_RS06825 PF00877 NlpC/P60 family SPH_RS06825 PF13702 Lysozyme-like SPH_RS06835 PF12846 AAA-like domain SPH_RS06840 PF12648 SPH_RS06840 SPH_RS06845 PF07275 Antirestriction protein (ArdA) SPH_RS06855 PF01610 SPH_RS06855 SPH_RS06855 PF14690 SPH_RS06855 SPH_RS06860 PF00398 Ribosomal RNA adenine dimethylase SPH_RS06865 PF06308 SPH_RS06865 SPH_RS06870 PF07764 Omega Transcriptional Repressor SPH_RS06875 PF01381 Helix-turn-helix SPH_RS06875 PF02486 SPH_RS06875 SPH_RS06880 PF01580 FtsK/SpoIIIE family SPH_RS06885 PF06125 Bacterial protein of unknown function (DUF961) SPH_RS06890 PF06125 Bacterial protein of unknown function (DUF961) SPH_RS06895 PF00860 Permease family SPH_RS06900 PF00448 SRP54-type protein, GTPase domain SPH_RS06900 PF02881 SRP54-type protein, helical bundle domain SPH_RS06900 PF02978 Signal peptide binding domain SPH_RS06905 PF04297 Putative helix-turn-helix protein, YlxM / p13 like SPH_RS06910 PF09148 Domain of unknown function (DUF1934) SPH_RS06915 PF01966 HD domain SPH_RS06920 PF08282 haloacid dehalogenase-like hydrolase SPH_RS06925 PF02037 SAP domain SPH_RS06935 PF01245 Ribosomal protein L19 SPH_RS06940 PF02537 SPH_RS06940 SPH_RS06945 PF02537 SPH_RS06945 SPH_RS06950 PF01817 Chorismate mutase type II SPH_RS06955 PF00258 Flavodoxin SPH_RS06960 PF01368 DHH family SPH_RS06965 PF01197 Ribosomal protein L31 SPH_RS06980 PF13592 SPH_RS06980 SPH_RS06985 PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase SPH_RS06985 PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain SPH_RS07000 PF01609 Transposase DDE domain SPH_RS07005 PF13384 Homeodomain-like domain SPH_RS07005 PF13592 SPH_RS07005 SPH_RS07030 PF00665 Integrase core domain SPH_RS07030 PF13276 SPH_RS07030 SPH_RS07045 PF01813 ATP synthase subunit D SPH_RS07050 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07050 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07055 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07055 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07055 PF16886 SPH_RS07055 SPH_RS07060 PF01990 ATP synthase (F/14-kDa) subunit SPH_RS07065 PF01992 ATP synthase (C/AC39) subunit SPH_RS07075 PF00137 ATP synthase subunit C SPH_RS07080 PF01496 V-type ATPase 116kDa subunit family SPH_RS07090 PF00480 ROK family SPH_RS07095 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS07095 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPH_RS07100 PF02012 BNR/Asp-box repeat SPH_RS07100 PF02973 Sialidase, N-terminal domain SPH_RS07100 PF13088 BNR repeat-like domain SPH_RS07105 PF04074 Domain of unknown function (DUF386) SPH_RS07110 PF00474 Sodium:solute symporter family SPH_RS07115 PF00701 Dihydrodipicolinate synthetase family SPH_RS07120 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS07125 PF01380 SIS domain SPH_RS07125 PF01418 Helix-turn-helix domain, rpiR family SPH_RS07130 PF02517 CAAX protease self-immunity SPH_RS07145 PF02687 SPH_RS07145 SPH_RS07150 PF00005 ABC transporter SPH_RS07155 PF00005 ABC transporter SPH_RS07160 PF00069 Protein kinase domain SPH_RS07165 PF02517 CAAX protease self-immunity SPH_RS07170 PF01610 SPH_RS07170 SPH_RS07170 PF13542 SPH_RS07170 SPH_RS07170 PF14690 SPH_RS07170 SPH_RS07175 PF00542 Ribosomal protein L7/L12 C-terminal domain SPH_RS07175 PF16320 SPH_RS07175 SPH_RS07180 PF00466 Ribosomal protein L10 SPH_RS07185 PF01979 Amidohydrolase family SPH_RS07190 PF00005 ABC transporter SPH_RS07190 PF00664 ABC transporter transmembrane region SPH_RS07195 PF00005 ABC transporter SPH_RS07195 PF00664 ABC transporter transmembrane region SPH_RS07200 PF01625 Peptide methionine sulfoxide reductase SPH_RS07200 PF01641 SelR domain SPH_RS07210 PF00288 GHMP kinases N terminal domain SPH_RS07210 PF08544 GHMP kinases C terminal SPH_RS07215 PF00742 Homoserine dehydrogenase SPH_RS07215 PF03447 Homoserine dehydrogenase, NAD binding domain SPH_RS07220 PF05389 Negative regulator of genetic competence (MecA) SPH_RS07230 PF14296 SPH_RS07230 SPH_RS07235 PF00535 Glycosyl transferase family 2 SPH_RS07240 PF00534 Glycosyl transferases group 1 SPH_RS07245 PF04991 SPH_RS07245 SPH_RS07250 PF03816 Cell envelope-related transcriptional attenuator domain SPH_RS07255 PF00800 Prephenate dehydratase SPH_RS07260 PF01202 Shikimate kinase SPH_RS07265 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS07270 PF06133 Protein of unknown function (DUF964) SPH_RS07275 PF02153 Prephenate dehydrogenase SPH_RS07280 PF01264 Chorismate synthase SPH_RS07285 PF01761 3-dehydroquinate synthase SPH_RS07290 PF08501 Shikimate dehydrogenase substrate binding domain SPH_RS07295 PF01487 Type I 3-dehydroquinase SPH_RS07300 PF10672 S-adenosylmethionine-dependent methyltransferase SPH_RS07310 PF00005 ABC transporter SPH_RS07315 PF00128 Alpha amylase, catalytic domain SPH_RS07315 PF09154 Domain of unknown function (DUF1939) SPH_RS07320 PF01411 tRNA synthetases class II (A) SPH_RS07320 PF02272 DHHA1 domain SPH_RS07320 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPH_RS07325 PF04525 Tubby C 2 SPH_RS07335 PF13416 Bacterial extracellular solute-binding protein SPH_RS07340 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07345 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07350 PF00005 ABC transporter SPH_RS07350 PF08402 TOBE domain SPH_RS07355 PF01565 FAD binding domain SPH_RS07355 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SPH_RS07365 PF03306 Alpha-acetolactate decarboxylase SPH_RS07370 PF00155 Aminotransferase class I and II SPH_RS07370 PF00392 Bacterial regulatory proteins, gntR family SPH_RS07375 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS07380 PF01895 PhoU domain SPH_RS07385 PF00005 ABC transporter SPH_RS07390 PF00005 ABC transporter SPH_RS07395 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07400 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07405 PF12849 PBP superfamily domain SPH_RS07410 PF01189 NOL1/NOP2/sun family SPH_RS07410 PF13636 pre-rRNA processing and ribosome biogenesis SPH_RS07410 PF17125 SPH_RS07410 SPH_RS07410 PF17126 SPH_RS07410 SPH_RS07415 PF00459 Inositol monophosphatase family SPH_RS07420 PF05256 Uncharacterised protein family (UPF0223) SPH_RS07425 PF03960 ArsC family SPH_RS07430 PF07314 SPH_RS07430 SPH_RS07435 PF13242 HAD-hyrolase-like SPH_RS07435 PF13344 Haloacid dehalogenase-like hydrolase SPH_RS07440 PF01643 Acyl-ACP thioesterase SPH_RS07445 PF04055 Radical SAM superfamily SPH_RS07445 PF06969 HemN C-terminal domain SPH_RS07450 PF12732 SPH_RS07450 SPH_RS07455 PF06103 SPH_RS07455 SPH_RS07460 PF01790 SPH_RS07460 SPH_RS07465 PF02603 HPr Serine kinase N terminus SPH_RS07465 PF07475 HPr Serine kinase C-terminal domain SPH_RS07470 PF01165 Ribosomal protein S21 SPH_RS07475 PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SPH_RS07480 PF02547 Queuosine biosynthesis protein SPH_RS07485 PF01473 Putative cell wall binding repeat SPH_RS07495 PF13302 Acetyltransferase (GNAT) domain SPH_RS07500 PF02540 NAD synthase SPH_RS07505 PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family SPH_RS07515 PF01381 Helix-turn-helix SPH_RS07525 PF00005 ABC transporter SPH_RS07530 PF01136 SPH_RS07530 SPH_RS07530 PF16325 SPH_RS07530 SPH_RS07540 PF01136 SPH_RS07540 SPH_RS07540 PF16325 SPH_RS07540 SPH_RS07545 PF09499 SPH_RS07545 SPH_RS07550 PF09499 SPH_RS07550 SPH_RS07555 PF01555 DNA methylase SPH_RS07560 PF00117 Glutamine amidotransferase class-I SPH_RS07560 PF00958 GMP synthase C terminal domain SPH_RS07560 PF02540 NAD synthase SPH_RS07565 PF00392 Bacterial regulatory proteins, gntR family SPH_RS07565 PF07702 UTRA domain SPH_RS07570 PF00892 EamA-like transporter family SPH_RS07575 PF00144 Beta-lactamase SPH_RS07580 PF14506 CppA N-terminal SPH_RS07580 PF14507 CppA C-terminal SPH_RS07585 PF13472 GDSL-like Lipase/Acylhydrolase family SPH_RS07590 PF08282 haloacid dehalogenase-like hydrolase SPH_RS07600 PF09587 Bacterial capsule synthesis protein PGA_cap SPH_RS07615 PF01327 Polypeptide deformylase SPH_RS07620 PF00588 SpoU rRNA Methylase family SPH_RS07620 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPH_RS07625 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS07630 PF13268 SPH_RS07630 SPH_RS07635 PF00005 ABC transporter SPH_RS07640 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07645 PF03960 ArsC family SPH_RS07650 PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain SPH_RS07655 PF00583 Acetyltransferase (GNAT) family SPH_RS07660 PF08876 SPH_RS07660 SPH_RS07665 PF03006 SPH_RS07665 SPH_RS07670 PF01174 SNO glutamine amidotransferase family SPH_RS07675 PF01680 SOR/SNZ family SPH_RS07680 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS07680 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS07685 PF02424 ApbE family SPH_RS07690 PF03358 NADPH-dependent FMN reductase SPH_RS07695 PF03358 NADPH-dependent FMN reductase SPH_RS07695 PF13596 PAS domain SPH_RS07700 PF05979 Bacterial protein of unknown function (DUF896) SPH_RS07705 PF02092 SPH_RS07705 SPH_RS07710 PF02091 Glycyl-tRNA synthetase alpha subunit SPH_RS07720 PF00248 Aldo/keto reductase family SPH_RS07725 PF01522 Polysaccharide deacetylase SPH_RS07730 PF12784 SPH_RS07730 SPH_RS07735 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS07740 PF00270 DEAD/DEAH box helicase SPH_RS07740 PF00271 Helicase conserved C-terminal domain SPH_RS07745 PF13358 DDE superfamily endonuclease SPH_RS07755 PF00009 Elongation factor Tu GTP binding domain SPH_RS07755 PF03143 Elongation factor Tu C-terminal domain SPH_RS07755 PF03144 Elongation factor Tu domain 2 SPH_RS07765 PF00230 Major intrinsic protein SPH_RS07770 PF00746 SPH_RS07770 SPH_RS07775 PF06458 MucBP domain SPH_RS07790 PF13358 DDE superfamily endonuclease SPH_RS07795 PF01710 Transposase SPH_RS07800 PF01710 Transposase SPH_RS07805 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPH_RS07805 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPH_RS07805 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPH_RS07805 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPH_RS07815 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPH_RS07820 PF00005 ABC transporter SPH_RS07825 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS07830 PF13181 Tetratricopeptide repeat SPH_RS07830 PF13432 Tetratricopeptide repeat SPH_RS07835 PF01594 SPH_RS07835 SPH_RS07840 PF10282 Lactonase, 7-bladed beta-propeller SPH_RS07845 PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SPH_RS07845 PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SPH_RS07850 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07850 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07855 PF00231 ATP synthase SPH_RS07860 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPH_RS07860 PF00306 ATP synthase alpha/beta chain, C terminal domain SPH_RS07860 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPH_RS07865 PF00213 ATP synthase delta (OSCP) subunit SPH_RS07870 PF00430 ATP synthase B/B' CF(0) SPH_RS07875 PF00119 ATP synthase A chain SPH_RS07880 PF00137 ATP synthase subunit C SPH_RS07885 PF13936 Helix-turn-helix domain SPH_RS07890 PF13673 Acetyltransferase (GNAT) domain SPH_RS07895 PF01272 Transcription elongation factor, GreA/GreB, C-term SPH_RS07895 PF03449 Transcription elongation factor, N-terminal SPH_RS07900 PF02618 YceG-like family SPH_RS07905 PF13673 Acetyltransferase (GNAT) domain SPH_RS07910 PF13673 Acetyltransferase (GNAT) domain SPH_RS07915 PF01225 Mur ligase family, catalytic domain SPH_RS07915 PF02875 Mur ligase family, glutamate ligase domain SPH_RS07915 PF08245 Mur ligase middle domain SPH_RS07925 PF00176 SNF2 family N-terminal domain SPH_RS07925 PF00271 Helicase conserved C-terminal domain SPH_RS07925 PF08455 SPH_RS07925 SPH_RS07930 PF00155 Aminotransferase class I and II SPH_RS07935 PF01053 Cys/Met metabolism PLP-dependent enzyme SPH_RS07940 PF00005 ABC transporter SPH_RS07945 PF00664 ABC transporter transmembrane region SPH_RS07950 PF00664 ABC transporter transmembrane region SPH_RS07955 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS07960 PF01943 SPH_RS07960 SPH_RS07960 PF14667 Polysaccharide biosynthesis C-terminal domain SPH_RS07965 PF02875 Mur ligase family, glutamate ligase domain SPH_RS07965 PF08245 Mur ligase middle domain SPH_RS07970 PF05532 CsbD-like SPH_RS07980 PF08820 SPH_RS07980 SPH_RS07985 PF05708 Orthopoxvirus protein of unknown function (DUF830) SPH_RS07990 PF01368 DHH family SPH_RS07990 PF02833 DHHA2 domain SPH_RS07995 PF01541 GIY-YIG catalytic domain SPH_RS08000 PF05175 Methyltransferase small domain SPH_RS08005 PF00575 S1 RNA binding domain SPH_RS08010 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPH_RS08010 PF08282 haloacid dehalogenase-like hydrolase SPH_RS08015 PF01084 Ribosomal protein S18 SPH_RS08020 PF00436 Single-strand binding protein family SPH_RS08025 PF01250 Ribosomal protein S6 SPH_RS08030 PF00152 tRNA synthetases class II (D, K and N) SPH_RS08030 PF01336 OB-fold nucleic acid binding domain SPH_RS08035 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPH_RS08040 PF00155 Aminotransferase class I and II SPH_RS08055 PF03358 NADPH-dependent FMN reductase SPH_RS08060 PF03883 SPH_RS08060 SPH_RS08065 PF13129 SPH_RS08065 SPH_RS08075 PF01327 Polypeptide deformylase SPH_RS08080 PF02798 Glutathione S-transferase, N-terminal domain SPH_RS08080 PF13410 Glutathione S-transferase, C-terminal domain SPH_RS08085 PF00122 E1-E2 ATPase SPH_RS08085 PF00689 Cation transporting ATPase, C-terminus SPH_RS08085 PF00690 Cation transporter/ATPase, N-terminus SPH_RS08085 PF00702 haloacid dehalogenase-like hydrolase SPH_RS08090 PF01545 Cation efflux family SPH_RS08090 PF16916 SPH_RS08090 SPH_RS08095 PF00005 ABC transporter SPH_RS08095 PF12848 ABC transporter SPH_RS08095 PF16326 SPH_RS08095 SPH_RS08100 PF01743 Poly A polymerase head domain SPH_RS08100 PF12627 Probable RNA and SrmB- binding site of polymerase A SPH_RS08100 PF13735 tRNA nucleotidyltransferase domain 2 putative SPH_RS08105 PF01113 Dihydrodipicolinate reductase, N-terminus SPH_RS08105 PF05173 Dihydrodipicolinate reductase, C-terminus SPH_RS08110 PF02645 Uncharacterised protein, DegV family COG1307 SPH_RS08115 PF06619 Protein of unknown function (DUF1149) SPH_RS08120 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPH_RS08120 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPH_RS08120 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPH_RS08120 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPH_RS08125 PF07949 YbbR-like protein SPH_RS08130 PF02457 DisA bacterial checkpoint controller nucleotide-binding SPH_RS08140 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS08145 PF02650 WhiA C-terminal HTH domain SPH_RS08145 PF10298 WhiA N-terminal LAGLIDADG-like domain SPH_RS08145 PF14527 WhiA LAGLIDADG-like domain SPH_RS08150 PF01933 Uncharacterised protein family UPF0052 SPH_RS08155 PF03668 SPH_RS08155 SPH_RS08160 PF01042 Endoribonuclease L-PSP SPH_RS08165 PF01926 50S ribosome-binding GTPase SPH_RS08170 PF06689 ClpX C4-type zinc finger SPH_RS08170 PF07724 AAA domain (Cdc48 subfamily) SPH_RS08170 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS08180 PF00186 Dihydrofolate reductase SPH_RS08185 PF00210 Ferritin-like domain SPH_RS08190 PF01183 Glycosyl hydrolases family 25 SPH_RS08190 PF01473 Putative cell wall binding repeat SPH_RS08195 PF00121 Triosephosphate isomerase SPH_RS08200 PF07261 Replication initiation and membrane attachment SPH_RS08205 PF04204 Homoserine O-succinyltransferase SPH_RS08210 PF00156 Phosphoribosyl transferase domain SPH_RS08215 PF13847 Methyltransferase domain SPH_RS08225 PF00005 ABC transporter SPH_RS08225 PF08402 TOBE domain SPH_RS08235 PF00857 Isochorismatase family SPH_RS08240 PF06018 CodY GAF-like domain SPH_RS08240 PF08222 CodY helix-turn-helix domain SPH_RS08245 PF00270 DEAD/DEAH box helicase SPH_RS08245 PF00271 Helicase conserved C-terminal domain SPH_RS08250 PF07690 Major Facilitator Superfamily SPH_RS08255 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPH_RS08255 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPH_RS08260 PF08245 Mur ligase middle domain SPH_RS08260 PF08353 SPH_RS08260 SPH_RS08265 PF07685 CobB/CobQ-like glutamine amidotransferase domain SPH_RS08270 PF00557 Metallopeptidase family M24 SPH_RS08270 PF01321 Creatinase/Prolidase N-terminal domain SPH_RS08275 PF13333 SPH_RS08275 SPH_RS08280 PF13276 SPH_RS08280 SPH_RS08295 PF07155 ECF-type riboflavin transporter, S component SPH_RS08300 PF08543 Phosphomethylpyrimidine kinase SPH_RS08305 PF01416 tRNA pseudouridine synthase SPH_RS08315 PF07690 Major Facilitator Superfamily SPH_RS08325 PF03831 PhnA protein SPH_RS08325 PF08274 PhnA Zinc-Ribbon SPH_RS08330 PF02224 Cytidylate kinase SPH_RS08340 PF13370 4Fe-4S single cluster domain SPH_RS08345 PF00535 Glycosyl transferase family 2 SPH_RS08350 PF16363 SPH_RS08350 SPH_RS08360 PF01266 FAD dependent oxidoreductase SPH_RS08365 PF01784 NIF3 (NGG1p interacting factor 3) SPH_RS08370 PF04816 Family of unknown function (DUF633) SPH_RS08385 PF00665 Integrase core domain SPH_RS08385 PF13276 SPH_RS08385 SPH_RS08400 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS08400 PF02779 Transketolase, pyrimidine binding domain SPH_RS08400 PF02780 Transketolase, C-terminal domain SPH_RS08405 PF00834 Ribulose-phosphate 3 epimerase family SPH_RS08410 PF02378 Phosphotransferase system, EIIC SPH_RS08415 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS08420 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS08425 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS08430 PF00874 PRD domain SPH_RS08430 PF05043 Mga helix-turn-helix domain SPH_RS08430 PF08279 HTH domain SPH_RS08435 PF00122 E1-E2 ATPase SPH_RS08435 PF00702 haloacid dehalogenase-like hydrolase SPH_RS08440 PF01553 Acyltransferase SPH_RS08445 PF03596 SPH_RS08445 SPH_RS08450 PF00312 Ribosomal protein S15 SPH_RS08455 PF13460 NADH(P)-binding SPH_RS08470 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPH_RS08470 PF02824 TGS domain SPH_RS08470 PF03129 Anticodon binding domain SPH_RS08470 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPH_RS08475 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS08480 PF00072 Response regulator receiver domain SPH_RS08480 PF00486 Transcriptional regulatory protein, C terminal SPH_RS08485 PF11187 Protein of unknown function (DUF2974) SPH_RS08495 PF02082 Transcriptional regulator SPH_RS08500 PF12850 Calcineurin-like phosphoesterase superfamily domain SPH_RS08505 PF01325 Iron dependent repressor, N-terminal DNA binding domain SPH_RS08505 PF02742 Iron dependent repressor, metal binding and dimerisation domain SPH_RS08505 PF04023 FeoA domain SPH_RS08520 PF02580 D-Tyr-tRNA(Tyr) deacylase SPH_RS08525 PF02824 TGS domain SPH_RS08525 PF04607 Region found in RelA / SpoT proteins SPH_RS08525 PF13291 ACT domain SPH_RS08525 PF13328 HD domain SPH_RS08540 PF00753 Metallo-beta-lactamase superfamily SPH_RS08545 PF01431 Peptidase family M13 SPH_RS08545 PF05649 Peptidase family M13 SPH_RS08550 PF00005 ABC transporter SPH_RS08555 PF00950 SPH_RS08555 SPH_RS08560 PF01297 Periplasmic solute binding protein family SPH_RS08565 PF08534 Redoxin SPH_RS08570 PF02687 SPH_RS08570 SPH_RS08575 PF00005 ABC transporter SPH_RS08585 PF00300 Histidine phosphatase superfamily (branch 1) SPH_RS08600 PF00133 tRNA synthetases class I (I, L, M and V) SPH_RS08600 PF06827 Zinc finger found in FPG and IleRS SPH_RS08600 PF08264 Anticodon-binding domain of tRNA SPH_RS08615 PF05103 DivIVA protein SPH_RS08620 PF01479 S4 domain SPH_RS08625 PF02325 SPH_RS08625 SPH_RS08630 PF04472 Protein of unknown function (DUF552) SPH_RS08635 PF01168 Alanine racemase, N-terminal domain SPH_RS08640 PF00091 Tubulin/FtsZ family, GTPase domain SPH_RS08640 PF12327 FtsZ family, C-terminal domain SPH_RS08645 PF02491 SHS2 domain inserted in FTSA SPH_RS08645 PF11983 SPH_RS08645 SPH_RS08645 PF14450 Cell division protein FtsA SPH_RS08650 PF09529 SPH_RS08650 SPH_RS08655 PF00293 NUDIX domain SPH_RS08655 PF12535 Hydrolase of X-linked nucleoside diphosphate N terminal SPH_RS08660 PF01225 Mur ligase family, catalytic domain SPH_RS08660 PF02875 Mur ligase family, glutamate ligase domain SPH_RS08660 PF08245 Mur ligase middle domain SPH_RS08665 PF01820 D-ala D-ala ligase N-terminus SPH_RS08665 PF07478 D-ala D-ala ligase C-terminus SPH_RS08670 PF02132 RecR protein SPH_RS08670 PF13662 Toprim domain SPH_RS08675 PF00905 Penicillin binding protein transpeptidase domain SPH_RS08675 PF03717 Penicillin-binding Protein dimerisation domain SPH_RS08680 PF01380 SIS domain SPH_RS08680 PF01418 Helix-turn-helix domain, rpiR family SPH_RS08685 PF00480 ROK family SPH_RS08690 PF00701 Dihydrodipicolinate synthetase family SPH_RS08695 PF04854 SPH_RS08695 SPH_RS08710 PF04074 Domain of unknown function (DUF386) SPH_RS08715 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08720 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08725 PF01547 Bacterial extracellular solute-binding protein SPH_RS08730 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPH_RS08735 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPH_RS08735 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPH_RS08740 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08745 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS08750 PF01547 Bacterial extracellular solute-binding protein SPH_RS08755 PF04074 Domain of unknown function (DUF386) SPH_RS08760 PF02973 Sialidase, N-terminal domain SPH_RS08760 PF13088 BNR repeat-like domain SPH_RS08775 PF05448 Acetyl xylan esterase (AXE1) SPH_RS08780 PF00270 DEAD/DEAH box helicase SPH_RS08780 PF00271 Helicase conserved C-terminal domain SPH_RS08780 PF17191 SPH_RS08780 SPH_RS08785 PF00842 Alanine racemase, C-terminal domain SPH_RS08785 PF01168 Alanine racemase, N-terminal domain SPH_RS08790 PF01648 4'-phosphopantetheinyl transferase superfamily SPH_RS08795 PF00793 DAHP synthetase I family SPH_RS08800 PF00793 DAHP synthetase I family SPH_RS08805 PF01043 SecA preprotein cross-linking domain SPH_RS08805 PF02810 SEC-C motif SPH_RS08805 PF07516 SecA Wing and Scaffold domain SPH_RS08805 PF07517 SecA DEAD-like domain SPH_RS08815 PF00005 ABC transporter SPH_RS08850 PF01926 50S ribosome-binding GTPase SPH_RS08850 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPH_RS08855 PF00881 Nitroreductase family SPH_RS08860 PF01695 IstB-like ATP binding protein SPH_RS08860 PF07319 Primosomal protein DnaI N-terminus SPH_RS08865 PF07261 Replication initiation and membrane attachment SPH_RS08870 PF03477 ATP cone domain SPH_RS08875 PF00392 Bacterial regulatory proteins, gntR family SPH_RS08880 PF00005 ABC transporter SPH_RS08890 PF12698 ABC-2 family transporter protein SPH_RS08895 PF00005 ABC transporter SPH_RS08895 PF13732 SPH_RS08895 SPH_RS08910 PF09335 SPH_RS08910 SPH_RS08915 PF00480 ROK family SPH_RS08920 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS08920 PF00367 phosphotransferase system, EIIB SPH_RS08920 PF02378 Phosphotransferase system, EIIC SPH_RS08930 PF00251 Glycosyl hydrolases family 32 N-terminal domain SPH_RS08930 PF08244 Glycosyl hydrolases family 32 C terminal SPH_RS08940 PF00368 Hydroxymethylglutaryl-coenzyme A reductase SPH_RS08945 PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal SPH_RS08945 PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal SPH_RS08955 PF13359 SPH_RS08955 SPH_RS08965 PF12821 SPH_RS08965 SPH_RS08970 PF06738 SPH_RS08970 SPH_RS08975 PF00069 Protein kinase domain SPH_RS08975 PF03793 PASTA domain SPH_RS08980 PF13672 Protein phosphatase 2C SPH_RS08985 PF01029 NusB family SPH_RS08985 PF01189 NOL1/NOP2/sun family SPH_RS08990 PF00551 Formyl transferase SPH_RS08990 PF02911 Formyl transferase, C-terminal domain SPH_RS08995 PF00271 Helicase conserved C-terminal domain SPH_RS08995 PF04851 Type III restriction enzyme, res subunit SPH_RS09000 PF01192 RNA polymerase Rpb6 SPH_RS09005 PF00625 Guanylate kinase SPH_RS09010 PF00013 KH domain SPH_RS09010 PF01966 HD domain SPH_RS09010 PF12072 SPH_RS09010 SPH_RS09015 PF06769 Plasmid encoded toxin Txe SPH_RS09020 PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system SPH_RS09025 PF05636 HIGH Nucleotidyl Transferase SPH_RS09030 PF13649 Methyltransferase domain SPH_RS09035 PF02410 Oligomerisation domain SPH_RS09040 PF00857 Isochorismatase family SPH_RS09045 PF01966 HD domain SPH_RS09050 PF01467 Cytidylyltransferase SPH_RS09055 PF01985 CRS1 / YhbY (CRM) domain SPH_RS09060 PF01926 50S ribosome-binding GTPase SPH_RS09065 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS09070 PF01544 CorA-like Mg2+ transporter protein SPH_RS09075 PF00924 Mechanosensitive ion channel SPH_RS09085 PF06081 SPH_RS09085 SPH_RS09085 PF11728 DUF939 C-terminal domain SPH_RS09095 PF17000 SPH_RS09095 SPH_RS09100 PF16996 SPH_RS09100 SPH_RS09110 PF00534 Glycosyl transferases group 1 SPH_RS09115 PF01043 SecA preprotein cross-linking domain SPH_RS09115 PF07516 SecA Wing and Scaffold domain SPH_RS09115 PF07517 SecA DEAD-like domain SPH_RS09120 PF15432 SPH_RS09120 SPH_RS09125 PF16929 SPH_RS09125 SPH_RS09130 PF16993 SPH_RS09130 SPH_RS09135 PF00344 SecY translocase SPH_RS09140 PF00535 Glycosyl transferase family 2 SPH_RS09145 PF01501 Glycosyl transferase family 8 SPH_RS09150 PF01501 Glycosyl transferase family 8 SPH_RS09155 PF00535 Glycosyl transferase family 2 SPH_RS09160 PF01501 Glycosyl transferase family 8 SPH_RS09160 PF08759 Domain of unknown function (DUF1792) SPH_RS09175 PF00535 Glycosyl transferase family 2 SPH_RS09180 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS09185 PF01501 Glycosyl transferase family 8 SPH_RS09205 PF01710 Transposase SPH_RS09210 PF01047 MarR family SPH_RS09215 PF15507 Domain of unknown function (DUF4649) SPH_RS09220 PF00085 Thioredoxin SPH_RS09225 PF06508 Queuosine biosynthesis protein QueC SPH_RS09225 PF14489 QueF-like protein SPH_RS09235 PF00230 Major intrinsic protein SPH_RS09240 PF10978 SPH_RS09240 SPH_RS09250 PF01432 Peptidase family M3 SPH_RS09250 PF08439 Oligopeptidase F SPH_RS09255 PF04452 RNA methyltransferase SPH_RS09260 PF06325 Ribosomal protein L11 methyltransferase (PrmA) SPH_RS09265 PF00293 NUDIX domain SPH_RS09275 PF11217 Protein of unknown function (DUF3013) SPH_RS09285 PF07927 YcfA-like protein SPH_RS09300 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS09300 PF12002 MgsA AAA+ ATPase C terminal SPH_RS09300 PF16193 SPH_RS09300 SPH_RS09310 PF00251 Glycosyl hydrolases family 32 N-terminal domain SPH_RS09310 PF08244 Glycosyl hydrolases family 32 C terminal SPH_RS09315 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09320 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09325 PF13416 Bacterial extracellular solute-binding protein SPH_RS09330 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09330 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPH_RS09335 PF05043 Mga helix-turn-helix domain SPH_RS09335 PF08270 SPH_RS09335 SPH_RS09335 PF08280 M protein trans-acting positive regulator (MGA) HTH domain SPH_RS09350 PF10031 SPH_RS09350 SPH_RS09355 PF03780 SPH_RS09355 SPH_RS09360 PF05532 CsbD-like SPH_RS09365 PF13751 SPH_RS09365 SPH_RS09375 PF01925 SPH_RS09375 SPH_RS09380 PF03781 Sulfatase-modifying factor enzyme 1 SPH_RS09385 PF00884 Sulfatase SPH_RS09385 PF16347 SPH_RS09385 SPH_RS09390 PF02378 Phosphotransferase system, EIIC SPH_RS09395 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS09400 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS09410 PF02378 Phosphotransferase system, EIIC SPH_RS09415 PF00480 ROK family SPH_RS09420 PF00583 Acetyltransferase (GNAT) family SPH_RS09425 PF06750 SPH_RS09425 SPH_RS09430 PF00290 Tryptophan synthase alpha chain SPH_RS09435 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS09440 PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase SPH_RS09445 PF00218 Indole-3-glycerol phosphate synthase SPH_RS09450 PF00591 Glycosyl transferase family, a/b domain SPH_RS09450 PF02885 Glycosyl transferase family, helical bundle domain SPH_RS09455 PF00117 Glutamine amidotransferase class-I SPH_RS09460 PF00425 chorismate binding enzyme SPH_RS09460 PF04715 Anthranilate synthase component I, N terminal region SPH_RS09475 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09475 PF13377 Periplasmic binding protein-like domain SPH_RS09485 PF02308 SPH_RS09485 SPH_RS09490 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09495 PF00005 ABC transporter SPH_RS09495 PF08402 TOBE domain SPH_RS09500 PF13343 Bacterial extracellular solute-binding protein SPH_RS09505 PF08975 Domain of unknown function (DUF1868) SPH_RS09515 PF04650 SPH_RS09515 SPH_RS09515 PF12708 Pectate lyase superfamily protein SPH_RS09515 PF13229 Right handed beta helix region SPH_RS09530 PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family SPH_RS09535 PF02397 SPH_RS09535 SPH_RS09540 PF00005 ABC transporter SPH_RS09540 PF00664 ABC transporter transmembrane region SPH_RS09545 PF00005 ABC transporter SPH_RS09545 PF00664 ABC transporter transmembrane region SPH_RS09550 PF04239 Protein of unknown function (DUF421) SPH_RS09555 PF11694 SPH_RS09555 SPH_RS09560 PF11694 SPH_RS09560 SPH_RS09565 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS09580 PF00156 Phosphoribosyl transferase domain SPH_RS09585 PF00860 Permease family SPH_RS09590 PF04556 SPH_RS09590 SPH_RS09595 PF01555 DNA methylase SPH_RS09600 PF02086 D12 class N6 adenine-specific DNA methyltransferase SPH_RS09605 PF03061 Thioesterase superfamily SPH_RS09610 PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain SPH_RS09610 PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain SPH_RS09615 PF00288 GHMP kinases N terminal domain SPH_RS09615 PF08544 GHMP kinases C terminal SPH_RS09615 PF10509 Galactokinase galactose-binding signature SPH_RS09620 PF00356 Bacterial regulatory proteins, lacI family SPH_RS09620 PF13377 Periplasmic binding protein-like domain SPH_RS09625 PF00107 Zinc-binding dehydrogenase SPH_RS09625 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS09630 PF13411 MerR HTH family regulatory protein SPH_RS09635 PF01545 Cation efflux family SPH_RS09640 PF00440 Bacterial regulatory proteins, tetR family SPH_RS09640 PF14278 SPH_RS09640 SPH_RS09645 PF04973 SPH_RS09645 SPH_RS09650 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09650 PF04069 Substrate binding domain of ABC-type glycine betaine transport system SPH_RS09655 PF00005 ABC transporter SPH_RS09660 PF07366 SnoaL-like polyketide cyclase SPH_RS09660 PF12680 SnoaL-like domain SPH_RS09665 PF01047 MarR family SPH_RS09675 PF05343 M42 glutamyl aminopeptidase SPH_RS09680 PF01370 NAD dependent epimerase/dehydratase family SPH_RS09690 PF01032 FecCD transport family SPH_RS09695 PF01032 FecCD transport family SPH_RS09700 PF00005 ABC transporter SPH_RS09705 PF01497 Periplasmic binding protein SPH_RS09710 PF01809 SPH_RS09710 SPH_RS09715 PF00849 RNA pseudouridylate synthase SPH_RS09715 PF01479 S4 domain SPH_RS09720 PF04079 Putative transcriptional regulators (Ypuh-like) SPH_RS09725 PF02616 ScpA/B protein SPH_RS09730 PF00589 Phage integrase family SPH_RS09730 PF02899 Phage integrase, N-terminal SAM-like domain SPH_RS09735 PF00571 CBS domain SPH_RS09740 PF12850 Calcineurin-like phosphoesterase superfamily domain SPH_RS09745 PF01725 Ham1 family SPH_RS09750 PF01177 Asp/Glu/Hydantoin racemase SPH_RS09755 PF03672 SPH_RS09755 SPH_RS09765 PF00128 Alpha amylase, catalytic domain SPH_RS09765 PF16657 SPH_RS09765 SPH_RS09770 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPH_RS09770 PF00367 phosphotransferase system, EIIB SPH_RS09770 PF02378 Phosphotransferase system, EIIC SPH_RS09775 PF00392 Bacterial regulatory proteins, gntR family SPH_RS09775 PF07702 UTRA domain SPH_RS09780 PF13542 SPH_RS09780 SPH_RS09780 PF14690 SPH_RS09780 SPH_RS09785 PF01610 SPH_RS09785 SPH_RS09790 PF01610 SPH_RS09790 SPH_RS09795 PF00005 ABC transporter SPH_RS09795 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPH_RS09800 PF00005 ABC transporter SPH_RS09800 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPH_RS09805 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09805 PF12911 SPH_RS09805 SPH_RS09810 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09815 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPH_RS09820 PF04932 SPH_RS09820 SPH_RS09825 PF00128 Alpha amylase, catalytic domain SPH_RS09830 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09835 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS09840 PF13416 Bacterial extracellular solute-binding protein SPH_RS09845 PF02065 Melibiase SPH_RS09845 PF16874 SPH_RS09845 SPH_RS09845 PF16875 SPH_RS09845 SPH_RS09850 PF02311 AraC-like ligand binding domain SPH_RS09850 PF12833 Helix-turn-helix domain SPH_RS09855 PF02237 Biotin protein ligase C terminal domain SPH_RS09855 PF03099 Biotin/lipoate A/B protein ligase family SPH_RS09855 PF08279 HTH domain SPH_RS09860 PF13542 SPH_RS09860 SPH_RS09860 PF14690 SPH_RS09860 SPH_RS09865 PF01610 SPH_RS09865 SPH_RS09985 PF02631 RecX family SPH_RS09990 PF04167 Protein of unknown function (DUF402) SPH_RS10000 PF13542 SPH_RS10000 SPH_RS10000 PF14690 SPH_RS10000 SPH_RS10005 PF01610 SPH_RS10005 SPH_RS10010 PF01610 SPH_RS10010 SPH_RS10015 PF00118 TCP-1/cpn60 chaperonin family SPH_RS10020 PF00166 Chaperonin 10 Kd subunit SPH_RS10025 PF00436 Single-strand binding protein family SPH_RS10030 PF00106 short chain dehydrogenase SPH_RS10035 PF01588 Putative tRNA binding domain SPH_RS10035 PF14794 Domain of unknown function (DUF4479) SPH_RS10040 PF00085 Thioredoxin SPH_RS10045 PF15513 Domain of unknown function (DUF4651) SPH_RS10050 PF01473 Putative cell wall binding repeat SPH_RS10060 PF04397 LytTr DNA-binding domain SPH_RS10065 PF01569 PAP2 superfamily SPH_RS10070 PF09966 Uncharacterized protein conserved in bacteria (DUF2200) SPH_RS10075 PF00005 ABC transporter SPH_RS10085 PF12802 MarR family SPH_RS10090 PF01709 Transcriptional regulator SPH_RS10095 PF01289 Thiol-activated cytolysin SPH_RS10110 PF14015 SPH_RS10110 SPH_RS10120 PF13359 SPH_RS10120 SPH_RS10125 PF03009 Glycerophosphoryl diester phosphodiesterase family SPH_RS10125 PF16387 SPH_RS10125 SPH_RS10130 PF13343 Bacterial extracellular solute-binding protein SPH_RS10135 PF00005 ABC transporter SPH_RS10135 PF08402 TOBE domain SPH_RS10140 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS10145 PF02308 SPH_RS10145 SPH_RS10150 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS10155 PF00356 Bacterial regulatory proteins, lacI family SPH_RS10155 PF13416 Bacterial extracellular solute-binding protein SPH_RS10160 PF13613 SPH_RS10160 SPH_RS10165 PF13359 SPH_RS10165 SPH_RS10200 PF01381 Helix-turn-helix SPH_RS10205 PF01473 Putative cell wall binding repeat SPH_RS10210 PF01554 MatE SPH_RS10215 PF00154 recA bacterial DNA recombination protein SPH_RS10220 PF00994 Probable molybdopterin binding domain SPH_RS10220 PF02464 Competence-damaged protein SPH_RS10225 PF03816 Cell envelope-related transcriptional attenuator domain SPH_RS10230 PF00583 Acetyltransferase (GNAT) family SPH_RS10235 PF02367 Uncharacterised P-loop hydrolase UPF0079 SPH_RS10245 PF01381 Helix-turn-helix SPH_RS10255 PF09683 Bacteriocin (Lactococcin_972) SPH_RS10260 PF07242 SPH_RS10260 SPH_RS10265 PF00005 ABC transporter SPH_RS10275 PF00334 Nucleoside diphosphate kinase SPH_RS10280 PF00623 RNA polymerase Rpb1, domain 2 SPH_RS10280 PF04983 RNA polymerase Rpb1, domain 3 SPH_RS10280 PF04997 RNA polymerase Rpb1, domain 1 SPH_RS10280 PF04998 RNA polymerase Rpb1, domain 5 SPH_RS10280 PF05000 RNA polymerase Rpb1, domain 4 SPH_RS10285 PF00562 RNA polymerase Rpb2, domain 6 SPH_RS10285 PF04560 RNA polymerase Rpb2, domain 7 SPH_RS10285 PF04561 RNA polymerase Rpb2, domain 2 SPH_RS10285 PF04563 RNA polymerase beta subunit SPH_RS10285 PF04565 RNA polymerase Rpb2, domain 3 SPH_RS10285 PF10385 RNA polymerase beta subunit external 1 domain SPH_RS10295 PF00571 CBS domain SPH_RS10295 PF01595 SPH_RS10295 SPH_RS10295 PF03471 Transporter associated domain SPH_RS10300 PF01223 DNA/RNA non-specific endonuclease SPH_RS10305 PF11772 SPH_RS10305 SPH_RS10310 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPH_RS10315 PF06612 SPH_RS10315 SPH_RS10320 PF05362 Lon protease (S16) C-terminal proteolytic domain SPH_RS10320 PF13180 PDZ domain SPH_RS10325 PF01467 Cytidylyltransferase SPH_RS10330 PF03602 Conserved hypothetical protein 95 SPH_RS10335 PF03590 Aspartate-ammonia ligase SPH_RS10340 PF01027 Inhibitor of apoptosis-promoting Bax1 SPH_RS10345 PF00588 SpoU rRNA Methylase family SPH_RS10345 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPH_RS10350 PF00708 Acylphosphatase SPH_RS10355 PF02096 60Kd inner membrane protein SPH_RS10360 PF04055 Radical SAM superfamily SPH_RS10360 PF13353 4Fe-4S single cluster domain SPH_RS10365 PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain SPH_RS10365 PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain SPH_RS10370 PF00156 Phosphoribosyl transferase domain SPH_RS10370 PF09182 Bacterial purine repressor, N-terminal SPH_RS10375 PF01966 HD domain SPH_RS10380 PF02646 SPH_RS10380 SPH_RS10385 PF04263 Thiamin pyrophosphokinase, catalytic domain SPH_RS10385 PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain SPH_RS10390 PF00834 Ribulose-phosphate 3 epimerase family SPH_RS10395 PF03193 Protein of unknown function, DUF258 SPH_RS10395 PF16745 SPH_RS10395 SPH_RS10400 PF00398 Ribosomal RNA adenine dimethylase SPH_RS10410 PF00005 ABC transporter SPH_RS10415 PF07242 SPH_RS10415 SPH_RS10420 PF09683 Bacteriocin (Lactococcin_972) SPH_RS10425 PF01381 Helix-turn-helix SPH_RS10430 PF13331 SPH_RS10430 SPH_RS10430 PF13662 Toprim domain SPH_RS10435 PF01026 TatD related DNase SPH_RS10440 PF00746 SPH_RS10440 SPH_RS10440 PF07564 SPH_RS10440 SPH_RS10445 PF00468 Ribosomal protein L34 SPH_RS10450 PF00155 Aminotransferase class I and II SPH_RS10460 PF00582 Universal stress protein family SPH_RS10465 PF01503 Phosphoribosyl-ATP pyrophosphohydrolase SPH_RS10465 PF08282 haloacid dehalogenase-like hydrolase SPH_RS10470 PF00710 Asparaginase SPH_RS10480 PF00356 Bacterial regulatory proteins, lacI family SPH_RS10480 PF13377 Periplasmic binding protein-like domain SPH_RS10485 PF00072 Response regulator receiver domain SPH_RS10485 PF00196 Bacterial regulatory proteins, luxR family SPH_RS10490 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS10490 PF07730 Histidine kinase SPH_RS10495 PF01061 SPH_RS10495 SPH_RS10500 PF00005 ABC transporter SPH_RS10590 PF00467 KOW motif SPH_RS10590 PF02357 Transcription termination factor nusG SPH_RS10595 PF00584 SecE/Sec61-gamma subunits of protein translocation complex SPH_RS10600 PF00471 Ribosomal protein L33 SPH_RS10605 PF00905 Penicillin binding protein transpeptidase domain SPH_RS10605 PF00912 Transglycosylase SPH_RS10610 PF00849 RNA pseudouridylate synthase SPH_RS10615 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPH_RS10615 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPH_RS10620 PF02687 SPH_RS10620 SPH_RS10625 PF13358 DDE superfamily endonuclease SPH_RS10635 PF01710 Transposase SPH_RS10640 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain SPH_RS10640 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain SPH_RS10645 PF07158 SPH_RS10645 SPH_RS10650 PF13555 P-loop containing region of AAA domain SPH_RS10655 PF00392 Bacterial regulatory proteins, gntR family SPH_RS10655 PF07702 UTRA domain SPH_RS10660 PF00232 Glycosyl hydrolase family 1 SPH_RS10665 PF02378 Phosphotransferase system, EIIC SPH_RS10670 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS10675 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPH_RS10680 PF00171 Aldehyde dehydrogenase family SPH_RS10680 PF00465 Iron-containing alcohol dehydrogenase SPH_RS10685 PF02493 MORN repeat SPH_RS10690 PF01451 Low molecular weight phosphotyrosine protein phosphatase SPH_RS10695 PF02699 Preprotein translocase subunit SPH_RS10700 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS10700 PF02779 Transketolase, pyrimidine binding domain SPH_RS10700 PF02780 Transketolase, C-terminal domain SPH_RS10705 PF13483 Beta-lactamase superfamily domain SPH_RS10710 PF00874 PRD domain SPH_RS10715 PF00596 Class II Aldolase and Adducin N-terminal domain SPH_RS10720 PF01261 Xylose isomerase-like TIM barrel SPH_RS10725 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPH_RS10730 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS10735 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS10740 PF03611 SPH_RS10740 SPH_RS10750 PF01424 R3H domain SPH_RS10750 PF13083 KH domain SPH_RS10750 PF14804 Jag N-terminus SPH_RS10755 PF02096 60Kd inner membrane protein SPH_RS10760 PF00825 Ribonuclease P SPH_RS10765 PF00871 Acetokinase family SPH_RS10770 PF02384 N-6 DNA Methylase SPH_RS10775 PF13847 Methyltransferase domain SPH_RS10790 PF15980 SPH_RS10790 SPH_RS10795 PF11773 SPH_RS10795 SPH_RS10805 PF13544 SPH_RS10805 SPH_RS10810 PF00482 Type II secretion system (T2SS), protein F SPH_RS10815 PF00437 Type II/IV secretion system protein SPH_RS10820 PF06279 SPH_RS10820 SPH_RS10825 PF01610 SPH_RS10825 SPH_RS10825 PF13542 SPH_RS10825 SPH_RS10825 PF14690 SPH_RS10825 SPH_RS10830 PF00107 Zinc-binding dehydrogenase SPH_RS10830 PF08240 Alcohol dehydrogenase GroES-like domain SPH_RS10835 PF01979 Amidohydrolase family SPH_RS10840 PF01757 SPH_RS10840 SPH_RS10845 PF01702 Queuine tRNA-ribosyltransferase SPH_RS10850 PF06161 SPH_RS10850 SPH_RS10865 PF01047 MarR family SPH_RS10870 PF01476 LysM domain SPH_RS10875 PF13419 Haloacid dehalogenase-like hydrolase SPH_RS10880 PF01554 MatE SPH_RS10885 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS10885 PF14821 Threonine synthase N terminus SPH_RS10905 PF03372 Endonuclease/Exonuclease/phosphatase family SPH_RS10915 PF01580 FtsK/SpoIIIE family SPH_RS10940 PF11372 SPH_RS10940 SPH_RS10945 PF00589 Phage integrase family SPH_RS10945 PF14657 SPH_RS10945 SPH_RS10950 PF13328 HD domain SPH_RS10960 PF00149 Calcineurin-like phosphoesterase SPH_RS10965 PF01610 SPH_RS10965 SPH_RS10965 PF13542 SPH_RS10965 SPH_RS10965 PF14690 SPH_RS10965 SPH_RS11050 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPH_RS11055 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPH_RS11060 PF00342 Phosphoglucose isomerase SPH_RS11070 PF07722 Peptidase C26 SPH_RS11075 PF00005 ABC transporter SPH_RS11075 PF00664 ABC transporter transmembrane region SPH_RS11080 PF02371 SPH_RS11080 SPH_RS11085 PF00005 ABC transporter SPH_RS11085 PF00664 ABC transporter transmembrane region SPH_RS11090 PF00488 MutS domain V SPH_RS11090 PF01624 MutS domain I SPH_RS11090 PF05188 MutS domain II SPH_RS11090 PF05190 MutS family domain IV SPH_RS11090 PF05192 MutS domain III SPH_RS11095 PF01316 Arginine repressor, DNA binding domain SPH_RS11095 PF02863 Arginine repressor, C-terminal domain SPH_RS11100 PF00750 tRNA synthetases class I (R) SPH_RS11100 PF03485 Arginyl tRNA synthetase N terminal domain SPH_RS11100 PF05746 DALR anticodon binding domain SPH_RS11105 PF13359 SPH_RS11105 SPH_RS11110 PF06172 Cupin superfamily (DUF985) SPH_RS11115 PF00072 Response regulator receiver domain SPH_RS11115 PF00486 Transcriptional regulatory protein, C terminal SPH_RS11120 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS11120 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS11125 PF12849 PBP superfamily domain SPH_RS11130 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11135 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11140 PF00005 ABC transporter SPH_RS11145 PF01895 PhoU domain SPH_RS11150 PF13701 SPH_RS11150 SPH_RS11155 PF01381 Helix-turn-helix SPH_RS11160 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPH_RS11160 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPH_RS11165 PF00483 Nucleotidyl transferase SPH_RS11180 PF01694 Rhomboid family SPH_RS11185 PF01812 5-formyltetrahydrofolate cyclo-ligase family SPH_RS11190 PF01546 Peptidase family M20/M25/M40 SPH_RS11190 PF07687 Peptidase dimerisation domain SPH_RS11195 PF00132 Bacterial transferase hexapeptide (six repeats) SPH_RS11195 PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal SPH_RS11195 PF14602 Hexapeptide repeat of succinyl-transferase SPH_RS11200 PF00892 EamA-like transporter family SPH_RS11205 PF00905 Penicillin binding protein transpeptidase domain SPH_RS11205 PF00912 Transglycosylase SPH_RS11210 PF00579 tRNA synthetases class I (W and Y) SPH_RS11210 PF01479 S4 domain SPH_RS11215 PF00122 E1-E2 ATPase SPH_RS11215 PF00702 haloacid dehalogenase-like hydrolase SPH_RS11225 PF13847 Methyltransferase domain SPH_RS11245 PF00343 Carbohydrate phosphorylase SPH_RS11250 PF02446 4-alpha-glucanotransferase SPH_RS11260 PF13416 Bacterial extracellular solute-binding protein SPH_RS11265 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11270 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11275 PF06691 SPH_RS11275 SPH_RS11280 PF00356 Bacterial regulatory proteins, lacI family SPH_RS11280 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPH_RS11285 PF02588 SPH_RS11285 SPH_RS11285 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPH_RS11290 PF00152 tRNA synthetases class II (D, K and N) SPH_RS11290 PF01336 OB-fold nucleic acid binding domain SPH_RS11290 PF02938 GAD domain SPH_RS11305 PF02517 CAAX protease self-immunity SPH_RS11310 PF11368 SPH_RS11310 SPH_RS11320 PF01381 Helix-turn-helix SPH_RS11335 PF03129 Anticodon binding domain SPH_RS11335 PF13393 Histidyl-tRNA synthetase SPH_RS11345 PF12844 Helix-turn-helix domain SPH_RS11350 PF01883 Domain of unknown function DUF59 SPH_RS11360 PF00920 Dehydratase family SPH_RS11365 PF02779 Transketolase, pyrimidine binding domain SPH_RS11365 PF02780 Transketolase, C-terminal domain SPH_RS11370 PF00456 Transketolase, thiamine diphosphate binding domain SPH_RS11375 PF03611 SPH_RS11375 SPH_RS11380 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS11385 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPH_RS11385 PF00874 PRD domain SPH_RS11385 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPH_RS11390 PF01145 SPFH domain / Band 7 family SPH_RS11400 PF01783 Ribosomal L32p protein family SPH_RS11405 PF00471 Ribosomal protein L33 SPH_RS11410 PF01473 Putative cell wall binding repeat SPH_RS11410 PF13306 Leucine rich repeats (6 copies) SPH_RS11415 PF04326 Divergent AAA domain SPH_RS11420 PF13613 SPH_RS11420 SPH_RS11425 PF13359 SPH_RS11425 SPH_RS11440 PF00480 ROK family SPH_RS11445 PF01074 Glycosyl hydrolases family 38 N-terminal domain SPH_RS11445 PF09261 Alpha mannosidase, middle domain SPH_RS11450 PF06824 Protein of unknown function (DUF1237) SPH_RS11455 PF07971 Glycosyl hydrolase family 92 SPH_RS11460 PF01120 Alpha-L-fucosidase SPH_RS11465 PF02274 Amidinotransferase SPH_RS11470 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPH_RS11470 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPH_RS11475 PF00696 Amino acid kinase family SPH_RS11480 PF03606 SPH_RS11480 SPH_RS11485 PF01546 Peptidase family M20/M25/M40 SPH_RS11495 PF04650 SPH_RS11495 SPH_RS11505 PF01145 SPFH domain / Band 7 family SPH_RS11510 PF00465 Iron-containing alcohol dehydrogenase SPH_RS11515 PF02952 L-fucose isomerase, C-terminal domain SPH_RS11515 PF07881 L-fucose isomerase, first N-terminal domain SPH_RS11515 PF07882 L-fucose isomerase, second N-terminal domain SPH_RS11520 PF00754 F5/8 type C domain SPH_RS11520 PF08306 Glycosyl hydrolase family 98 SPH_RS11520 PF08307 Glycosyl hydrolase family 98 C-terminal domain SPH_RS11525 PF14498 Glycosyl hydrolase family 65, N-terminal domain SPH_RS11530 PF03613 SPH_RS11530 SPH_RS11535 PF03609 SPH_RS11535 SPH_RS11540 PF03830 PTS system sorbose subfamily IIB component SPH_RS11545 PF03610 PTS system fructose IIA component SPH_RS11550 PF05025 RbsD / FucU transport protein family SPH_RS11555 PF00596 Class II Aldolase and Adducin N-terminal domain SPH_RS11560 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPH_RS11560 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPH_RS11565 PF00455 SPH_RS11565 SPH_RS11565 PF08220 DeoR-like helix-turn-helix domain SPH_RS11570 PF01297 Periplasmic solute binding protein family SPH_RS11570 PF09223 YodA lipocalin-like domain SPH_RS11575 PF00950 SPH_RS11575 SPH_RS11580 PF00005 ABC transporter SPH_RS11585 PF01047 MarR family SPH_RS11590 PF04914 DltD C-terminal region SPH_RS11590 PF04915 DltD N-terminal region SPH_RS11590 PF04918 DltD central region SPH_RS11595 PF00550 Phosphopantetheine attachment site SPH_RS11600 PF03062 SPH_RS11600 SPH_RS11605 PF00501 AMP-binding enzyme SPH_RS11605 PF13193 AMP-binding enzyme C-terminal domain SPH_RS11610 PF12459 SPH_RS11610 SPH_RS11615 PF07690 Major Facilitator Superfamily SPH_RS11620 PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) SPH_RS11620 PF08388 SPH_RS11620 SPH_RS11640 PF00230 Major intrinsic protein SPH_RS11645 PF01266 FAD dependent oxidoreductase SPH_RS11645 PF16901 SPH_RS11645 SPH_RS11650 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPH_RS11650 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPH_RS11655 PF05043 Mga helix-turn-helix domain SPH_RS11660 PF01430 Hsp33 protein SPH_RS11665 PF01207 Dihydrouridine synthase (Dus) SPH_RS11670 PF00746 SPH_RS11670 SPH_RS11670 PF05062 RICH domain SPH_RS11675 PF04650 SPH_RS11675 SPH_RS11680 PF01610 SPH_RS11680 SPH_RS11680 PF13542 SPH_RS11680 SPH_RS11680 PF14690 SPH_RS11680 SPH_RS11685 PF01473 Putative cell wall binding repeat SPH_RS11685 PF04650 SPH_RS11685 SPH_RS11685 PF05062 RICH domain SPH_RS11690 PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SPH_RS11695 PF00512 His Kinase A (phospho-acceptor) domain SPH_RS11695 PF00672 HAMP domain SPH_RS11695 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPH_RS11700 PF00072 Response regulator receiver domain SPH_RS11700 PF00486 Transcriptional regulatory protein, C terminal SPH_RS11705 PF00004 ATPase family associated with various cellular activities (AAA) SPH_RS11705 PF02861 Clp amino terminal domain SPH_RS11705 PF07724 AAA domain (Cdc48 subfamily) SPH_RS11705 PF10431 C-terminal, D2-small domain, of ClpB protein SPH_RS11710 PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) SPH_RS11715 PF00005 ABC transporter SPH_RS11720 PF09084 NMT1/THI5 like SPH_RS11725 PF00528 Binding-protein-dependent transport system inner membrane component SPH_RS11730 PF01910 Domain of unknown function DUF77 SPH_RS11735 PF01473 Putative cell wall binding repeat SPH_RS11735 PF05257 CHAP domain SPH_RS11735 PF08460 Bacterial SH3 domain SPH_RS11740 PF06257 Protein of unknown function (DUF1021) SPH_RS11745 PF00772 DnaB-like helicase N terminal domain SPH_RS11745 PF03796 DnaB-like helicase C terminal domain SPH_RS11750 PF01281 Ribosomal protein L9, N-terminal domain SPH_RS11750 PF03948 Ribosomal protein L9, C-terminal domain SPH_RS11755 PF01368 DHH family SPH_RS11755 PF02272 DHHA1 domain SPH_RS11760 PF02482 Sigma 54 modulation protein / S30EA ribosomal protein SPH_RS11760 PF16321 SPH_RS11760 SPH_RS11765 PF00156 Phosphoribosyl transferase domain SPH_RS11770 PF00271 Helicase conserved C-terminal domain SPH_RS11770 PF04851 Type III restriction enzyme, res subunit SPH_RS11775 PF01205 Uncharacterized protein family UPF0029 SPH_RS11775 PF09186 Domain of unknown function (DUF1949) SPH_RS11780 PF00291 Pyridoxal-phosphate dependent enzyme SPH_RS11785 PF00889 Elongation factor TS SPH_RS11790 PF00318 Ribosomal protein S2 SPH_RS11795 PF05257 CHAP domain SPH_RS11800 PF04093 SPH_RS11800 SPH_RS11805 PF04085 rod shape-determining protein MreC SPH_RS11810 PF02361 Cobalt transport protein SPH_RS11815 PF00005 ABC transporter SPH_RS11820 PF00005 ABC transporter SPH_RS11825 PF01066 CDP-alcohol phosphatidyltransferase SPH_RS11830 PF13413 Helix-turn-helix domain SPH_RS11835 PF00675 Insulinase (Peptidase family M16) SPH_RS11835 PF05193 Peptidase M16 inactive domain SPH_RS11840 PF05193 Peptidase M16 inactive domain SPH_RS11845 PF13275 S4 domain SPH_RS11850 PF13175 AAA ATPase domain SPH_RS11855 PF00478 IMP dehydrogenase / GMP reductase domain SPH_RS11855 PF00571 CBS domain SPH_RS11860 PF00579 tRNA synthetases class I (W and Y) SPH_RS11865 PF00005 ABC transporter SPH_RS11865 PF12848 ABC transporter SPH_RS11870 PF09586 SPH_RS11870 SPH_RS11880 PF12698 ABC-2 family transporter protein SPH_RS11885 PF00440 Bacterial regulatory proteins, tetR family SPH_RS11900 PF00072 Response regulator receiver domain SPH_RS11900 PF04397 LytTr DNA-binding domain SPH_RS11905 PF14501 GHKL domain SPH_RS11910 PF03047 SPH_RS11910 SPH_RS11925 PF13180 PDZ domain SPH_RS11925 PF13365 Trypsin-like peptidase domain SPH_RS11930 PF02195 ParB-like nuclease domain SPH_RS11950 PF08797 HIRAN domain SPH_RS11960 PF06605 Prophage endopeptidase tail