locus-tag	class	description
INV104_RS00010	COG0592	DNA-directed DNA polymerase activity
INV104_RS00020	COG0012	GTP binding
INV104_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
INV104_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
INV104_RS00055	COG0037	tRNA processing
INV104_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
INV104_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
INV104_RS00115	COG3335	DDE superfamily endonuclease
INV104_RS00150	COG0756	dUTP diphosphatase activity
INV104_RS00160	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
INV104_RS00175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INV104_RS00195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INV104_RS00195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
INV104_RS00200	COG1832	CoA-binding protein
INV104_RS00210	COG2855	membrane
INV104_RS00215	COG0436	Aminotransferase
INV104_RS00230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INV104_RS00250	COG2274	protein secretion by the type I secretion system
INV104_RS00255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INV104_RS00265	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
INV104_RS00270	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
INV104_RS00280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
INV104_RS00295	COG0151	Belongs to the GarS family
INV104_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
INV104_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
INV104_RS00320	COG3583	domain protein
INV104_RS00320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
INV104_RS00320	COG3064	Membrane
INV104_RS00335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS00340	COG3715	PTS system
INV104_RS00345	COG3716	PTS system mannose fructose sorbose family IID component
INV104_RS00355	COG2222	sugar isomerase
INV104_RS00365	COG2514	catechol 2,3-dioxygenase activity
INV104_RS00370	COG1937	Protein conserved in bacteria
INV104_RS00395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INV104_RS00400	COG0569	domain protein
INV104_RS00410	COG1215	transferase activity, transferring glycosyl groups
INV104_RS00430	COG5002	protein histidine kinase activity
INV104_RS00445	COG4209	transmembrane transport
INV104_RS00450	COG0395	ABC-type sugar transport system, permease component
INV104_RS00455	COG1653	transport
INV104_RS00485	COG1695	Transcriptional regulator
INV104_RS00510	COG0546	phosphoglycolate phosphatase activity
INV104_RS00515	COG1760	l-serine dehydratase
INV104_RS00520	COG1760	l-serine dehydratase
INV104_RS00615	COG0445	tRNA wobble uridine modification
INV104_RS00650	COG1214	PFAM Peptidase M22, glycoprotease
INV104_RS00685	COG0438	transferase activity, transferring glycosyl groups
INV104_RS00730	COG1396	sequence-specific DNA binding
INV104_RS00770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS00780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS00785	COG1464	Belongs to the NlpA lipoprotein family
INV104_RS00790	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INV104_RS00795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
INV104_RS00815	COG2972	Histidine kinase
INV104_RS00820	COG2207	Transcriptional regulator
INV104_RS00820	COG4753	response regulator
INV104_RS00830	COG1780	Probably involved in ribonucleotide reductase function
INV104_RS00865	COG0019	diaminopimelate decarboxylase activity
INV104_RS00895	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
INV104_RS00895	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
INV104_RS00915	COG2818	Glycosylase
INV104_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
INV104_RS00945	COG0006	proline dipeptidase activity
INV104_RS00955	COG1393	Belongs to the ArsC family
INV104_RS00980	COG0285	dihydrofolate synthase activity
INV104_RS00990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
INV104_RS01055	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
INV104_RS01080	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
INV104_RS01120	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
INV104_RS01135	COG0201	protein transport
INV104_RS01145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
INV104_RS01150	COG0257	Belongs to the bacterial ribosomal protein bL36 family
INV104_RS01160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
INV104_RS01165	COG0202	RNA polymerase activity
INV104_RS01175	COG3830	Belongs to the UPF0237 family
INV104_RS01195	COG1178	ABC-type Fe3 transport system permease component
INV104_RS01200	COG3842	ATPase activity
INV104_RS01220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INV104_RS01225	COG1349	DNA-binding transcription factor activity
INV104_RS01235	COG1447	Phosphotransferase system cellobiose-specific component IIA
INV104_RS01240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS01245	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS01250	COG1882	Formate acetyltransferase
INV104_RS01295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
INV104_RS01300	COG4589	Belongs to the CDS family
INV104_RS01305	COG0750	zinc metalloprotease
INV104_RS01315	COG2723	6-phospho-beta-galactosidase activity
INV104_RS01320	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
INV104_RS01330	COG1523	belongs to the glycosyl hydrolase 13 family
INV104_RS01355	COG2176	DNA-directed DNA polymerase activity
INV104_RS01375	COG2309	aminopeptidase activity
INV104_RS01380	COG2261	transglycosylase associated protein
INV104_RS01385	COG1187	pseudouridine synthase activity
INV104_RS01395	COG3579	cysteine-type endopeptidase activity
INV104_RS01400	COG3716	PTS system mannose fructose sorbose family IID component
INV104_RS01405	COG3715	PTS system
INV104_RS01415	COG1064	alcohol dehydrogenase
INV104_RS01420	COG0561	phosphatase activity
INV104_RS01425	COG2252	PERMEase
INV104_RS01440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
INV104_RS01445	COG0285	dihydrofolate synthase activity
INV104_RS01455	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
INV104_RS01455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
INV104_RS01465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
INV104_RS01480	COG2723	6-phospho-beta-galactosidase activity
INV104_RS01495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS01495	COG3711	transcriptional antiterminator
INV104_RS01510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS01525	COG0386	Belongs to the glutathione peroxidase family
INV104_RS01530	COG5492	domain, Protein
INV104_RS01555	COG1028	Short-chain dehydrogenase reductase Sdr
INV104_RS01565	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
INV104_RS01570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS01575	COG3715	PTS system
INV104_RS01580	COG3716	PTS system mannose fructose sorbose family IID component
INV104_RS01595	COG1609	Transcriptional regulator
INV104_RS01625	COG4839	cell division protein FtsL
INV104_RS01630	COG0768	penicillin binding
INV104_RS01690	COG3344	reverse transcriptase
INV104_RS01705	COG0366	Alpha amylase catalytic
INV104_RS01710	COG4166	transmembrane transport
INV104_RS01750	COG3944	biosynthesis protein
INV104_RS01810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
INV104_RS01820	COG1088	dTDP-glucose 4,6-dehydratase activity
INV104_RS01835	COG4372	Transposase
INV104_RS01840	COG4166	transmembrane transport
INV104_RS01845	COG0366	Alpha amylase catalytic
INV104_RS01850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INV104_RS01875	COG0116	Belongs to the methyltransferase superfamily
INV104_RS01885	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
INV104_RS01890	COG0745	RESPONSE REGULATOR receiver
INV104_RS01940	COG4585	Histidine kinase
INV104_RS01945	COG2197	response regulator
INV104_RS01980	COG2801	Transposase and inactivated derivatives
INV104_RS01995	COG2213	PTS system mannitol-specific
INV104_RS02000	COG3711	transcriptional antiterminator
INV104_RS02005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS02030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
INV104_RS02035	COG0681	Belongs to the peptidase S26 family
INV104_RS02060	COG1115	amino acid carrier protein
INV104_RS02085	COG0527	aspartate kinase activity
INV104_RS02090	COG1024	Enoyl-CoA hydratase
INV104_RS02095	COG1846	Transcriptional regulator
INV104_RS02105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
INV104_RS02115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
INV104_RS02120	COG1028	Short-chain dehydrogenase reductase Sdr
INV104_RS02125	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
INV104_RS02140	COG0439	Biotin carboxylase
INV104_RS02145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
INV104_RS02180	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
INV104_RS02205	COG0227	Belongs to the bacterial ribosomal protein bL28 family
INV104_RS02215	COG1461	Dihydroxyacetone kinase
INV104_RS02220	COG0028	Belongs to the TPP enzyme family
INV104_RS02225	COG0440	acetolactate synthase activity
INV104_RS02245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
INV104_RS02260	COG0765	amino acid transport
INV104_RS02285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
INV104_RS02290	COG1882	Formate acetyltransferase
INV104_RS02330	COG1940	carbohydrate kinase activity
INV104_RS02330	COG1846	Transcriptional regulator
INV104_RS02335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS02345	COG1447	Phosphotransferase system cellobiose-specific component IIA
INV104_RS02350	COG2723	6-phospho-beta-galactosidase activity
INV104_RS02355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS02355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS02360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
INV104_RS02365	COG0569	domain protein
INV104_RS02385	COG1122	ATPase activity
INV104_RS02400	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
INV104_RS02405	COG0671	phosphoesterase, PA-phosphatase related
INV104_RS02440	COG1247	-acetyltransferase
INV104_RS02450	COG0504	CTP synthase activity
INV104_RS02455	COG1283	sodium-dependent phosphate transmembrane transporter activity
INV104_RS02475	COG0789	Transcriptional regulator
INV104_RS02480	COG0174	glutamine synthetase
INV104_RS02490	COG0732	type I restriction modification DNA specificity domain
INV104_RS02495	COG0732	type I restriction modification DNA specificity domain
INV104_RS02535	COG0484	heat shock protein binding
INV104_RS02550	COG0537	adenosine 5'-monophosphoramidase activity
INV104_RS02555	COG1131	(ABC) transporter
INV104_RS02580	COG3290	protein histidine kinase activity
INV104_RS02590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INV104_RS02595	COG2274	protein secretion by the type I secretion system
INV104_RS02675	COG1266	CAAX protease self-immunity
INV104_RS02695	COG0195	Participates in both transcription termination and antitermination
INV104_RS02700	COG2740	Nucleic-acid-binding protein implicated in transcription termination
INV104_RS02775	COG0519	Catalyzes the synthesis of GMP from XMP
INV104_RS02785	COG0525	valine-tRNA ligase activity
INV104_RS02800	COG2801	Transposase and inactivated derivatives
INV104_RS02805	COG2801	Transposase and inactivated derivatives
INV104_RS02825	COG3711	transcriptional antiterminator
INV104_RS02830	COG1263	PTS System
INV104_RS02830	COG2190	(PTS) system
INV104_RS02830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS02845	COG0456	acetyltransferase
INV104_RS02850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INV104_RS02850	COG0072	phenylalanine-tRNA ligase activity
INV104_RS02865	COG3620	sequence-specific DNA binding
INV104_RS02885	COG1045	serine acetyltransferase
INV104_RS02895	COG0215	cysteine-tRNA ligase activity
INV104_RS02900	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
INV104_RS02935	COG0577	efflux transmembrane transporter activity
INV104_RS02940	COG1136	(ABC) transporter
INV104_RS02945	COG0577	efflux transmembrane transporter activity
INV104_RS02950	COG0745	RESPONSE REGULATOR receiver
INV104_RS02955	COG5002	protein histidine kinase activity
INV104_RS02960	COG0191	fructose-bisphosphate aldolase activity
INV104_RS02965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
INV104_RS02970	COG0765	amino acid transport
INV104_RS02975	COG0765	amino acid transport
INV104_RS02980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS02990	COG1126	abc transporter atp-binding protein
INV104_RS02995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
INV104_RS02995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
INV104_RS03035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS03050	COG1573	uracil-dna glycosylase
INV104_RS03060	COG1114	Component of the transport system for branched-chain amino acids
INV104_RS03065	COG1363	Peptidase, m42
INV104_RS03105	COG4555	ABC transporter
INV104_RS03140	COG1404	Belongs to the peptidase S8 family
INV104_RS03150	COG4372	Transposase
INV104_RS03170	COG3775	system Galactitol-specific IIC component
INV104_RS03180	COG3250	beta-galactosidase activity
INV104_RS03200	COG1242	4 iron, 4 sulfur cluster binding
INV104_RS03205	COG1242	4 iron, 4 sulfur cluster binding
INV104_RS03210	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
INV104_RS03230	COG0785	Cytochrome C biogenesis protein
INV104_RS03235	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INV104_RS03240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INV104_RS03240	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INV104_RS03245	COG4753	response regulator
INV104_RS03245	COG2207	Transcriptional regulator
INV104_RS03250	COG2972	Histidine kinase
INV104_RS03260	COG3064	Membrane
INV104_RS03265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INV104_RS03280	COG1940	carbohydrate kinase activity
INV104_RS03300	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
INV104_RS03305	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
INV104_RS03315	COG0300	oxidoreductase activity
INV104_RS03330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
INV104_RS03340	COG1187	pseudouridine synthase activity
INV104_RS03345	COG1217	gtp-binding protein TYPA
INV104_RS03365	COG1136	(ABC) transporter
INV104_RS03380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
INV104_RS03410	COG2826	transposase and inactivated derivatives, IS30 family
INV104_RS03420	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
INV104_RS03445	COG1131	(ABC) transporter
INV104_RS03455	COG1126	abc transporter atp-binding protein
INV104_RS03460	COG1129	ABC transporter
INV104_RS03465	COG4215	(ABC) transporter
INV104_RS03470	COG0765	amino acid transport
INV104_RS03475	COG1304	FMN binding
INV104_RS03480	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
INV104_RS03485	COG1304	FMN binding
INV104_RS03495	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
INV104_RS03500	COG0352	thiamine-phosphate diphosphorylase activity
INV104_RS03510	COG4172	Belongs to the ABC transporter superfamily
INV104_RS03520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
INV104_RS03535	COG0352	thiamine-phosphate diphosphorylase activity
INV104_RS03555	COG2217	Heavy metal translocating P-type atpase
INV104_RS03560	COG0028	Belongs to the TPP enzyme family
INV104_RS03570	COG2723	6-phospho-beta-galactosidase activity
INV104_RS03575	COG1482	cell wall glycoprotein biosynthetic process
INV104_RS03580	COG0733	neurotransmitter:sodium symporter activity
INV104_RS03600	COG2081	HI0933 family
INV104_RS03605	COG1307	EDD domain protein, DegV family
INV104_RS03615	COG2131	deaminase
INV104_RS03620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
INV104_RS03665	COG0517	IMP dehydrogenase activity
INV104_RS03665	COG0617	tRNA 3'-terminal CCA addition
INV104_RS03665	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
INV104_RS03670	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
INV104_RS03675	COG2884	Cell division ATP-binding protein ftsE
INV104_RS03680	COG2177	Part of the ABC transporter FtsEX involved in
INV104_RS03690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS03690	COG2190	(PTS) system
INV104_RS03690	COG1263	PTS System
INV104_RS03700	COG0513	Belongs to the DEAD box helicase family
INV104_RS03710	COG0167	dihydroorotate dehydrogenase activity
INV104_RS03720	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
INV104_RS03725	COG4470	Protein conserved in bacteria
INV104_RS03755	COG0488	(ABC) transporter
INV104_RS03780	COG1837	Belongs to the UPF0109 family
INV104_RS03800	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
INV104_RS03800	COG1328	CTP reductase activity
INV104_RS03810	COG4443	Transcriptional Coactivator p15 (PC4)
INV104_RS03815	COG1268	BioY protein
INV104_RS03820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INV104_RS03825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
INV104_RS03830	COG1136	(ABC) transporter
INV104_RS03835	COG0577	efflux transmembrane transporter activity
INV104_RS03840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INV104_RS03840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INV104_RS03860	COG4989	oxidoreductase activity
INV104_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
INV104_RS03900	COG0745	RESPONSE REGULATOR receiver
INV104_RS03905	COG5002	protein histidine kinase activity
INV104_RS03925	COG0772	Belongs to the SEDS family
INV104_RS03930	COG0693	protein deglycase activity
INV104_RS03940	COG0187	DNA topoisomerase II activity
INV104_RS03960	COG0494	nUDIX hydrolase
INV104_RS03975	COG0542	response to heat
INV104_RS03980	COG4703	Protein of unknown function (DUF1797)
INV104_RS03985	COG0765	amino acid transport
INV104_RS03990	COG1126	abc transporter atp-binding protein
INV104_RS03995	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
INV104_RS04000	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
INV104_RS04020	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
INV104_RS04060	COG2813	Specifically methylates the guanine in position
INV104_RS04065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
INV104_RS04075	COG0295	cytidine deaminase activity
INV104_RS04080	COG1744	ABC transporter substrate-binding protein PnrA-like
INV104_RS04085	COG3845	ABC transporter
INV104_RS04090	COG4603	Belongs to the binding-protein-dependent transport system permease family
INV104_RS04095	COG1079	Belongs to the binding-protein-dependent transport system permease family
INV104_RS04115	COG2801	Transposase and inactivated derivatives
INV104_RS04125	COG0187	DNA topoisomerase II activity
INV104_RS04135	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INV104_RS04140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
INV104_RS04145	COG4166	transmembrane transport
INV104_RS04180	COG0539	negative regulation of cytoplasmic translation
INV104_RS04185	COG1956	GAF domain-containing protein
INV104_RS04190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
INV104_RS04205	COG0719	Fe-S assembly protein
INV104_RS04210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
INV104_RS04220	COG0719	Fe-S assembly protein
INV104_RS04225	COG1686	Belongs to the peptidase S11 family
INV104_RS04230	COG0628	permease
INV104_RS04240	COG1349	DNA-binding transcription factor activity
INV104_RS04245	COG1105	Belongs to the carbohydrate kinase PfkB family
INV104_RS04250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS04250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INV104_RS04250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
INV104_RS04255	COG1674	ftsk spoiiie
INV104_RS04255	COG0697	spore germination
INV104_RS04265	COG1104	cysteine desulfurase activity
INV104_RS04325	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
INV104_RS04370	COG1737	Transcriptional regulator
INV104_RS04375	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
INV104_RS04380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INV104_RS04385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
INV104_RS04395	COG4409	exo-alpha-(2->6)-sialidase activity
INV104_RS04400	COG0673	inositol 2-dehydrogenase activity
INV104_RS04415	COG1269	ATP hydrolysis coupled proton transport
INV104_RS04420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
INV104_RS04470	COG1438	arginine binding
INV104_RS04490	COG0469	pyruvate kinase activity
INV104_RS04500	COG0582	viral genome integration into host DNA
INV104_RS04535	COG3689	TIGRFAM TIGR03943 family protein
INV104_RS04540	COG0701	Predicted permease
INV104_RS04550	COG2183	response to ionizing radiation
INV104_RS04570	COG1136	(ABC) transporter
INV104_RS04575	COG0577	efflux transmembrane transporter activity
INV104_RS04595	COG1982	Orn Lys Arg decarboxylase major
INV104_RS04610	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
INV104_RS04630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
INV104_RS04635	COG0561	phosphatase activity
INV104_RS04655	COG0583	DNA-binding transcription factor activity
INV104_RS04660	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
INV104_RS04665	COG0564	pseudouridine synthase activity
INV104_RS04670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
INV104_RS04685	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
INV104_RS04695	COG0470	DNA polymerase III
INV104_RS04740	COG0528	UMP kinase activity
INV104_RS04750	COG2996	Protein conserved in bacteria
INV104_RS04760	COG1702	phosphate starvation-inducible protein PhoH
INV104_RS04775	COG0686	Belongs to the AlaDH PNT family
INV104_RS04780	COG0686	Belongs to the AlaDH PNT family
INV104_RS04785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
INV104_RS04790	COG1596	polysaccharide export
INV104_RS04790	COG1555	photosystem II stabilization
INV104_RS04795	COG0658	competence protein
INV104_RS04795	COG2333	competence protein COMEC
INV104_RS04805	COG1131	(ABC) transporter
INV104_RS04835	COG0543	2 iron, 2 sulfur cluster binding
INV104_RS04840	COG0167	dihydroorotate dehydrogenase activity
INV104_RS04845	COG5263	repeat protein
INV104_RS04845	COG4193	domain, Protein
INV104_RS04850	COG1293	RNA-binding protein homologous to eukaryotic snRNP
INV104_RS04860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
INV104_RS04870	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
INV104_RS04875	COG0237	dephospho-CoA kinase activity
INV104_RS04880	COG2814	Major facilitator Superfamily
INV104_RS04885	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INV104_RS04895	COG0557	exoribonuclease II activity
INV104_RS04905	COG0500	methyltransferase
INV104_RS04905	COG3615	Tellurite resistance protein tehB
INV104_RS04920	COG4122	O-methyltransferase activity
INV104_RS04930	COG2801	Transposase and inactivated derivatives
INV104_RS04950	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
INV104_RS04970	COG0494	nUDIX hydrolase
INV104_RS04980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
INV104_RS04990	COG2176	DNA-directed DNA polymerase activity
INV104_RS04995	COG0584	glycerophosphoryl diester phosphodiesterase
INV104_RS05015	COG0785	Cytochrome C biogenesis protein
INV104_RS05020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INV104_RS05025	COG0531	amino acid
INV104_RS05030	COG3443	Belongs to the bacterial solute-binding protein 9 family
INV104_RS05030	COG0803	Belongs to the bacterial solute-binding protein 9 family
INV104_RS05070	COG2195	Cleaves the N-terminal amino acid of tripeptides
INV104_RS05090	COG0681	Belongs to the peptidase S26 family
INV104_RS05100	COG4509	Sortase family
INV104_RS05110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
INV104_RS05115	COG1970	mechanosensitive ion channel activity
INV104_RS05125	COG4708	membrane
INV104_RS05135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
INV104_RS05150	COG1942	4-Oxalocrotonate Tautomerase
INV104_RS05155	COG1435	thymidine kinase activity
INV104_RS05165	COG2890	protein-(glutamine-N5) methyltransferase activity
INV104_RS05190	COG0741	lytic transglycosylase activity
INV104_RS05200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INV104_RS05225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INV104_RS05230	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INV104_RS05280	COG1597	lipid kinase activity
INV104_RS05285	COG0366	Alpha amylase catalytic
INV104_RS05325	COG1131	(ABC) transporter
INV104_RS05345	COG0772	Belongs to the SEDS family
INV104_RS05350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
INV104_RS05365	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
INV104_RS05370	COG0358	DNA primase activity
INV104_RS05375	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
INV104_RS05380	COG2151	metal-sulfur cluster biosynthetic enzyme
INV104_RS05385	COG0438	transferase activity, transferring glycosyl groups
INV104_RS05390	COG0438	transferase activity, transferring glycosyl groups
INV104_RS05415	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INV104_RS05425	COG4109	DRTGG domain
INV104_RS05430	COG0024	Methionine aminopeptidase
INV104_RS05445	COG0210	DNA helicase
INV104_RS05455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
INV104_RS05475	COG1104	cysteine desulfurase activity
INV104_RS05480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
INV104_RS05490	COG2357	RelA SpoT domain protein
INV104_RS05500	COG0564	pseudouridine synthase activity
INV104_RS05505	COG0280	phosphate acetyltransferase
INV104_RS05555	COG0196	riboflavin kinase activity
INV104_RS05560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INV104_RS05565	COG1307	EDD domain protein, DegV family
INV104_RS05575	COG0488	(ABC) transporter
INV104_RS05605	COG1523	belongs to the glycosyl hydrolase 13 family
INV104_RS05620	COG1012	belongs to the aldehyde dehydrogenase family
INV104_RS05625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
INV104_RS05635	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
INV104_RS05645	COG0560	Phosphoserine phosphatase
INV104_RS05650	COG0560	Phosphoserine phosphatase
INV104_RS05670	COG4974	Belongs to the 'phage' integrase family
INV104_RS05735	COG0582	viral genome integration into host DNA
INV104_RS05770	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
INV104_RS05770	COG3583	domain protein
INV104_RS05775	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
INV104_RS05795	COG0095	Lipoate-protein ligase
INV104_RS05800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INV104_RS05805	COG0508	dehydrogenase complex catalyzes the overall conversion of
INV104_RS05810	COG0022	dehydrogenase e1 component
INV104_RS05815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
INV104_RS05820	COG0534	Mate efflux family protein
INV104_RS05830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
INV104_RS05835	COG1051	belongs to the nudix hydrolase family
INV104_RS05850	COG1011	Hydrolase
INV104_RS05875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS05880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
INV104_RS05885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INV104_RS05890	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
INV104_RS05900	COG2723	6-phospho-beta-galactosidase activity
INV104_RS05915	COG3711	transcriptional antiterminator
INV104_RS05920	COG3684	Belongs to the aldolase LacD family
INV104_RS05975	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
INV104_RS05980	COG0497	DNA recombination
INV104_RS05985	COG1438	arginine binding
INV104_RS05990	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
INV104_RS06025	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
INV104_RS06045	COG3764	Sortase (surface protein transpeptidase)
INV104_RS06050	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
INV104_RS06060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
INV104_RS06075	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
INV104_RS06080	COG5002	protein histidine kinase activity
INV104_RS06085	COG0745	RESPONSE REGULATOR receiver
INV104_RS06090	COG1194	a g-specific adenine glycosylase
INV104_RS06105	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
INV104_RS06110	COG4684	Psort location CytoplasmicMembrane, score
INV104_RS06120	COG1827	regulation of RNA biosynthetic process
INV104_RS06140	COG0556	nucleotide-excision repair
INV104_RS06150	COG0765	amino acid transport
INV104_RS06155	COG1126	abc transporter atp-binding protein
INV104_RS06160	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
INV104_RS06165	COG0552	protein localization to endoplasmic reticulum
INV104_RS06170	COG0561	phosphatase activity
INV104_RS06175	COG0561	phosphatase activity
INV104_RS06180	COG1196	nuclear chromosome segregation
INV104_RS06205	COG1401	restriction endodeoxyribonuclease activity
INV104_RS06220	COG0066	3-isopropylmalate dehydratase activity
INV104_RS06230	COG0473	3-isopropylmalate dehydrogenase activity
INV104_RS06250	COG3142	Participates in the control of copper homeostasis
INV104_RS06255	COG2832	Protein of unknown function (DUF454)
INV104_RS06260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
INV104_RS06270	COG0758	DNA mediated transformation
INV104_RS06275	COG4750	Nucleotidyl transferase
INV104_RS06290	COG1063	alcohol dehydrogenase
INV104_RS06305	COG3475	LICD family
INV104_RS06310	COG3475	LICD family
INV104_RS06320	COG0505	Belongs to the CarA family
INV104_RS06335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
INV104_RS06350	COG0488	(ABC) transporter
INV104_RS06355	COG0501	Belongs to the peptidase M48B family
INV104_RS06360	COG1704	LemA family
INV104_RS06375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
INV104_RS06390	COG1078	dGTPase activity
INV104_RS06415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
INV104_RS06420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
INV104_RS06425	COG0077	Prephenate dehydratase
INV104_RS06425	COG1605	Chorismate mutase
INV104_RS06430	COG0716	FMN binding
INV104_RS06435	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
INV104_RS06460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
INV104_RS06505	COG0295	cytidine deaminase activity
INV104_RS06530	COG0395	ABC-type sugar transport system, permease component
INV104_RS06535	COG4209	transmembrane transport
INV104_RS06540	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
INV104_RS06555	COG2801	Transposase and inactivated derivatives
INV104_RS06570	COG0577	efflux transmembrane transporter activity
INV104_RS06570	COG1136	(ABC) transporter
INV104_RS06580	COG1770	oligopeptidase
INV104_RS06585	COG0515	serine threonine protein kinase
INV104_RS06620	COG0402	S-adenosylhomocysteine deaminase activity
INV104_RS06630	COG1132	(ABC) transporter
INV104_RS06635	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INV104_RS06635	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
INV104_RS06670	COG1215	transferase activity, transferring glycosyl groups
INV104_RS06680	COG3475	LICD family
INV104_RS06690	COG0077	Prephenate dehydratase
INV104_RS06695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
INV104_RS06700	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
INV104_RS06710	COG0287	Prephenate dehydrogenase
INV104_RS06735	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
INV104_RS06745	COG1131	(ABC) transporter
INV104_RS06785	COG3842	ATPase activity
INV104_RS06800	COG3527	Alpha-acetolactate decarboxylase
INV104_RS06805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
INV104_RS06810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS06815	COG0704	Plays a role in the regulation of phosphate uptake
INV104_RS06820	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INV104_RS06825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INV104_RS06830	COG0581	inorganic phosphate transmembrane transporter activity
INV104_RS06835	COG0573	inorganic phosphate transmembrane transporter activity
INV104_RS06840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
INV104_RS06845	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
INV104_RS06845	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
INV104_RS06850	COG0483	inositol monophosphate 1-phosphatase activity
INV104_RS06860	COG1393	Belongs to the ArsC family
INV104_RS06870	COG0647	UMP catabolic process
INV104_RS06880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
INV104_RS06940	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
INV104_RS06960	COG1131	(ABC) transporter
INV104_RS06965	COG0826	peptidase U32
INV104_RS06975	COG0826	peptidase U32
INV104_RS07000	COG1132	(ABC) transporter
INV104_RS07005	COG1132	(ABC) transporter
INV104_RS07020	COG1129	ABC transporter
INV104_RS07060	COG2188	Transcriptional regulator
INV104_RS07065	COG0697	spore germination
INV104_RS07070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
INV104_RS07085	COG0561	phosphatase activity
INV104_RS07115	COG0492	ferredoxin-NADP+ reductase activity
INV104_RS07125	COG1126	abc transporter atp-binding protein
INV104_RS07135	COG1393	Belongs to the ArsC family
INV104_RS07155	COG1272	protein, Hemolysin III
INV104_RS07185	COG0431	NADPH-dependent FMN reductase
INV104_RS07185	COG3976	FMN-binding domain protein
INV104_RS07185	COG1053	succinate dehydrogenase
INV104_RS07220	COG0656	L-ascorbic acid biosynthetic process
INV104_RS07225	COG0726	polysaccharide deacetylase
INV104_RS07270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INV104_RS07320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
INV104_RS07330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
INV104_RS07335	COG1126	abc transporter atp-binding protein
INV104_RS07350	COG0628	permease
INV104_RS07355	COG2706	6-phosphogluconolactonase activity
INV104_RS07420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
INV104_RS07445	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
INV104_RS07450	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
INV104_RS07455	COG0626	cystathionine gamma-synthase activity
INV104_RS07465	COG1132	(ABC) transporter
INV104_RS07470	COG1132	(ABC) transporter
INV104_RS07475	COG4166	transmembrane transport
INV104_RS07480	COG2244	polysaccharide biosynthetic process
INV104_RS07485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
INV104_RS07515	COG2827	Endonuclease containing a URI domain
INV104_RS07520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
INV104_RS07525	COG1098	S1 RNA binding domain
INV104_RS07535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
INV104_RS07540	COG0629	single-stranded DNA binding
INV104_RS07550	COG0017	Asparaginyl-tRNA synthetase
INV104_RS07560	COG0436	Aminotransferase
INV104_RS07585	COG3711	transcriptional antiterminator
INV104_RS07605	COG0242	peptide deformylase activity
INV104_RS07610	COG0625	glutathione transferase activity
INV104_RS07620	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
INV104_RS07625	COG0488	(ABC) transporter
INV104_RS07630	COG0617	tRNA 3'-terminal CCA addition
INV104_RS07640	COG1307	EDD domain protein, DegV family
INV104_RS07660	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
INV104_RS07680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
INV104_RS07690	COG0251	oxidation-reduction process
INV104_RS07710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
INV104_RS07720	COG5263	repeat protein
INV104_RS07720	COG4193	domain, Protein
INV104_RS07730	COG3935	DnaD domain protein
INV104_RS07745	COG2226	methyltransferase
INV104_RS07755	COG3842	ATPase activity
INV104_RS07765	COG1335	isochorismatase
INV104_RS07775	COG0513	Belongs to the DEAD box helicase family
INV104_RS07785	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
INV104_RS07790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INV104_RS07795	COG3442	glutamine amidotransferase
INV104_RS07800	COG0006	proline dipeptidase activity
INV104_RS07810	COG2801	Transposase and inactivated derivatives
INV104_RS07825	COG4720	Psort location CytoplasmicMembrane, score
INV104_RS07830	COG0351	phosphomethylpyrimidine kinase
INV104_RS07855	COG2824	Alkylphosphonate utilization operon protein PhnA
INV104_RS07880	COG0463	Glycosyl transferase, family 2
INV104_RS07885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
INV104_RS07895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
INV104_RS07900	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
INV104_RS07905	COG2384	SAM-dependent methyltransferase
INV104_RS07910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
INV104_RS07915	COG0204	Acyl-transferase
INV104_RS07930	COG2910	NAD(P)H-binding
INV104_RS07955	COG5002	protein histidine kinase activity
INV104_RS07960	COG0745	RESPONSE REGULATOR receiver
INV104_RS07975	COG1959	2 iron, 2 sulfur cluster binding
INV104_RS08050	COG3590	peptidase
INV104_RS08070	COG0803	Belongs to the bacterial solute-binding protein 9 family
INV104_RS08075	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
INV104_RS08090	COG0577	efflux transmembrane transporter activity
INV104_RS08090	COG1136	(ABC) transporter
INV104_RS08135	COG3599	regulation of cell shape
INV104_RS08155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
INV104_RS08175	COG1051	belongs to the nudix hydrolase family
INV104_RS08180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
INV104_RS08195	COG0768	penicillin binding
INV104_RS08210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
INV104_RS08230	COG2731	YhcH YjgK YiaL family protein
INV104_RS08235	COG0395	ABC-type sugar transport system, permease component
INV104_RS08240	COG1175	transmembrane transport
INV104_RS08250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS08250	COG2190	(PTS) system
INV104_RS08250	COG1263	PTS System
INV104_RS08260	COG0673	inositol 2-dehydrogenase activity
INV104_RS08265	COG4409	exo-alpha-(2->6)-sialidase activity
INV104_RS08275	COG1175	transmembrane transport
INV104_RS08280	COG1653	transport
INV104_RS08300	COG3458	cephalosporin-C deacetylase activity
INV104_RS08305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
INV104_RS08320	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INV104_RS08325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
INV104_RS08330	COG0653	protein targeting
INV104_RS08340	COG1131	(ABC) transporter
INV104_RS08370	COG0778	Nitroreductase
INV104_RS08375	COG1484	DNA-dependent DNA replication
INV104_RS08390	COG1725	Transcriptional regulator
INV104_RS08395	COG1131	(ABC) transporter
INV104_RS08405	COG1668	transmembrane transport
INV104_RS08410	COG4152	abc transporter atp-binding protein
INV104_RS08430	COG1940	carbohydrate kinase activity
INV104_RS08435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS08435	COG1263	PTS System
INV104_RS08435	COG2190	(PTS) system
INV104_RS08445	COG1621	beta-fructofuranosidase activity
INV104_RS08450	COG1609	Transcriptional regulator
INV104_RS08460	COG3425	synthase
INV104_RS08485	COG0515	serine threonine protein kinase
INV104_RS08485	COG2815	serine threonine protein kinase
INV104_RS08490	COG0631	protein serine/threonine phosphatase activity
INV104_RS08495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
INV104_RS08495	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
INV104_RS08505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
INV104_RS08515	COG0194	GDP metabolic process
INV104_RS08540	COG2226	methyltransferase
INV104_RS08545	COG0799	negative regulation of ribosome biogenesis
INV104_RS08555	COG1713	HD superfamily hydrolase involved in NAD metabolism
INV104_RS08560	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
INV104_RS08565	COG1534	Rna-binding protein
INV104_RS08570	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
INV104_RS08585	COG0668	transmembrane transport
INV104_RS08615	COG0438	transferase activity, transferring glycosyl groups
INV104_RS08620	COG0438	transferase activity, transferring glycosyl groups
INV104_RS08625	COG0653	protein targeting
INV104_RS08645	COG0201	protein transport
INV104_RS08650	COG1215	transferase activity, transferring glycosyl groups
INV104_RS08655	COG1215	transferase activity, transferring glycosyl groups
INV104_RS08660	COG1442	glycosyl transferase family 8
INV104_RS08665	COG1442	glycosyl transferase family 8
INV104_RS08670	COG1442	glycosyl transferase family 8
INV104_RS08675	COG0438	transferase activity, transferring glycosyl groups
INV104_RS08680	COG1442	glycosyl transferase family 8
INV104_RS08680	COG1216	Glycosyl transferase, family 2
INV104_RS08685	COG1442	glycosyl transferase family 8
INV104_RS08690	COG1442	glycosyl transferase family 8
INV104_RS08690	COG1216	Glycosyl transferase, family 2
INV104_RS08695	COG1442	glycosyl transferase family 8
INV104_RS08695	COG1216	Glycosyl transferase, family 2
INV104_RS08725	COG3118	belongs to the thioredoxin family
INV104_RS08730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
INV104_RS08735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INV104_RS08750	COG1164	Oligoendopeptidase f
INV104_RS08755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
INV104_RS08760	COG2264	protein methyltransferase activity
INV104_RS08765	COG1051	belongs to the nudix hydrolase family
INV104_RS08805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
INV104_RS08815	COG1621	beta-fructofuranosidase activity
INV104_RS08820	COG0395	ABC-type sugar transport system, permease component
INV104_RS08835	COG1175	transmembrane transport
INV104_RS08845	COG1609	Transcriptional regulator
INV104_RS08850	COG3711	transcriptional antiterminator
INV104_RS08875	COG3237	CsbD-like
INV104_RS08895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
INV104_RS08905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS08910	COG1447	Phosphotransferase system cellobiose-specific component IIA
INV104_RS08915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS08930	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS08935	COG1846	Transcriptional regulator
INV104_RS08935	COG1940	carbohydrate kinase activity
INV104_RS08945	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
INV104_RS08985	COG0512	Glutamine amidotransferase of anthranilate synthase
INV104_RS08990	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
INV104_RS09015	COG1285	pathogenesis
INV104_RS09020	COG1178	ABC-type Fe3 transport system permease component
INV104_RS09050	COG5434	Belongs to the glycosyl hydrolase 28 family
INV104_RS09065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
INV104_RS09070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
INV104_RS09075	COG1132	(ABC) transporter
INV104_RS09080	COG1132	(ABC) transporter
INV104_RS09105	COG0708	Exodeoxyribonuclease III
INV104_RS09125	COG2233	PERMEase
INV104_RS09155	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
INV104_RS09160	COG1609	Transcriptional regulator
INV104_RS09165	COG1063	alcohol dehydrogenase
INV104_RS09170	COG0789	Transcriptional regulator
INV104_RS09175	COG1230	cation diffusion facilitator family transporter
INV104_RS09185	COG3201	nicotinamide mononucleotide transporter
INV104_RS09190	COG1174	glycine betaine transport
INV104_RS09215	COG1363	Peptidase, m42
INV104_RS09230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
INV104_RS09235	COG4605	iron ion homeostasis
INV104_RS09240	COG4604	ABC transporter, ATP-binding protein
INV104_RS09245	COG4607	ABC-type enterochelin transport system periplasmic component
INV104_RS09255	COG1187	pseudouridine synthase activity
INV104_RS09275	COG0517	IMP dehydrogenase activity
INV104_RS09285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
INV104_RS09300	COG0366	Alpha amylase catalytic
INV104_RS09305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS09305	COG1263	PTS System
INV104_RS09310	COG2188	Transcriptional regulator
INV104_RS09315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
INV104_RS09335	COG4608	Belongs to the ABC transporter superfamily
INV104_RS09340	COG0444	Belongs to the ABC transporter superfamily
INV104_RS09345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
INV104_RS09350	COG0601	transmembrane transport
INV104_RS09355	COG4166	transmembrane transport
INV104_RS09365	COG0366	Alpha amylase catalytic
INV104_RS09380	COG1175	transmembrane transport
INV104_RS09385	COG1653	transport
INV104_RS09390	COG3345	alpha-galactosidase
INV104_RS09395	COG2207	Transcriptional regulator
INV104_RS09400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
INV104_RS09400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
INV104_RS09520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
INV104_RS09555	COG4221	oxidoreductase activity
INV104_RS09560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
INV104_RS09565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
INV104_RS09600	COG1132	(ABC) transporter
INV104_RS09685	COG5632	N-Acetylmuramoyl-L-alanine amidase
INV104_RS09685	COG5263	repeat protein
INV104_RS09705	COG1316	TRANSCRIPTIONal
INV104_RS09715	COG0802	atpase or kinase
INV104_RS09745	COG1136	(ABC) transporter
INV104_RS09775	COG1253	flavin adenine dinucleotide binding
INV104_RS09790	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
INV104_RS09800	COG3480	Lon protease (S16) C-terminal proteolytic domain
INV104_RS09805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
INV104_RS09810	COG0742	ribosomal rna small subunit methyltransferase
INV104_RS09830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
INV104_RS09835	COG1254	Belongs to the acylphosphatase family
INV104_RS09845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
INV104_RS09855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
INV104_RS09870	COG1564	THIamine pyrophosphokinase
INV104_RS09880	COG1162	GTPase activity
INV104_RS09920	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
INV104_RS09925	COG0084	hydrolase, TatD family'
INV104_RS09945	COG0436	Aminotransferase
INV104_RS09955	COG0589	response to stress
INV104_RS09960	COG0561	phosphatase activity
INV104_RS09965	COG0252	asparaginase activity
INV104_RS09975	COG1609	Transcriptional regulator
INV104_RS09980	COG2197	response regulator
INV104_RS09985	COG4585	Histidine kinase
INV104_RS09990	COG0842	Transport permease protein
INV104_RS09995	COG1131	(ABC) transporter
INV104_RS10100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INV104_RS10105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INV104_RS10110	COG0564	pseudouridine synthase activity
INV104_RS10120	COG0577	efflux transmembrane transporter activity
INV104_RS10135	COG0157	Belongs to the NadC ModD family
INV104_RS10145	COG4133	protoheme IX ABC transporter activity
INV104_RS10150	COG2188	Transcriptional regulator
INV104_RS10155	COG2723	6-phospho-beta-galactosidase activity
INV104_RS10160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
INV104_RS10170	COG1447	Phosphotransferase system cellobiose-specific component IIA
INV104_RS10175	COG1012	belongs to the aldehyde dehydrogenase family
INV104_RS10175	COG1454	alcohol dehydrogenase
INV104_RS10185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
INV104_RS10195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
INV104_RS10215	COG3623	hexulose-6-phosphate isomerase
INV104_RS10225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS10235	COG3037	sugar-specific permease SgaT UlaA
INV104_RS10245	COG1847	R3H domain protein
INV104_RS10250	COG0706	membrane insertase activity
INV104_RS10305	COG4537	Required for transformation and DNA binding
INV104_RS10310	COG1459	type II secretion system
INV104_RS10315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
INV104_RS10325	COG1063	alcohol dehydrogenase
INV104_RS10350	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
INV104_RS10355	COG3759	membrane
INV104_RS10370	COG0131	Imidazoleglycerol-phosphate dehydratase
INV104_RS10370	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
INV104_RS10375	COG0534	Mate efflux family protein
INV104_RS10490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
INV104_RS10495	COG1132	(ABC) transporter
INV104_RS10505	COG1132	(ABC) transporter
INV104_RS10515	COG1438	arginine binding
INV104_RS10535	COG0745	RESPONSE REGULATOR receiver
INV104_RS10540	COG5002	protein histidine kinase activity
INV104_RS10545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
INV104_RS10550	COG0573	inorganic phosphate transmembrane transporter activity
INV104_RS10560	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
INV104_RS10565	COG0704	Plays a role in the regulation of phosphate uptake
INV104_RS10585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
INV104_RS10595	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
INV104_RS10610	COG0697	spore germination
INV104_RS10615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
INV104_RS10615	COG4499	WXG100 protein secretion system (Wss), protein YukC
INV104_RS10625	COG2217	Heavy metal translocating P-type atpase
INV104_RS10635	COG2226	methyltransferase
INV104_RS10655	COG0058	SHG alpha-glucan phosphorylase activity
INV104_RS10660	COG1640	4-alpha-glucanotransferase
INV104_RS10665	COG2182	Extracellular solute-binding protein
INV104_RS10670	COG1175	transmembrane transport
INV104_RS10675	COG3833	ABC-type maltose transport systems, permease component
INV104_RS10680	COG5521	maltodextrose utilization protein MalA
INV104_RS10685	COG1609	Transcriptional regulator
INV104_RS10695	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
INV104_RS10730	COG1476	TRANSCRIPTIONal
INV104_RS10760	COG2151	metal-sulfur cluster biosynthetic enzyme
INV104_RS10770	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
INV104_RS10775	COG3959	Transketolase, thiamine diphosphate binding domain
INV104_RS10790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
INV104_RS10810	COG0267	Belongs to the bacterial ribosomal protein bL33 family
INV104_RS10850	COG0383	alpha-mannosidase activity
INV104_RS10860	COG3537	Alpha-1,2-mannosidase
INV104_RS10880	COG0549	Belongs to the carbamate kinase family
INV104_RS10885	COG1288	antiporter activity
INV104_RS10890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
INV104_RS10915	COG1454	alcohol dehydrogenase
INV104_RS10935	COG3716	PTS system mannose fructose sorbose family IID component
INV104_RS10945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
INV104_RS10965	COG1070	Carbohydrate kinase
INV104_RS10975	COG0803	Belongs to the bacterial solute-binding protein 9 family
INV104_RS10975	COG3443	Belongs to the bacterial solute-binding protein 9 family
INV104_RS10980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
INV104_RS10985	COG1121	(ABC) transporter
INV104_RS10990	COG1846	Transcriptional regulator
INV104_RS10995	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
INV104_RS11005	COG1696	Membrane protein involved in D-alanine export
INV104_RS11020	COG2211	Major facilitator Superfamily
INV104_RS11025	COG3344	reverse transcriptase
INV104_RS11045	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
INV104_RS11050	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
INV104_RS11070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
INV104_RS11080	COG0366	Alpha amylase catalytic
INV104_RS11085	COG1755	Isoprenylcysteine carboxyl methyltransferase
INV104_RS11090	COG5002	protein histidine kinase activity
INV104_RS11095	COG0745	RESPONSE REGULATOR receiver
INV104_RS11100	COG0542	response to heat
INV104_RS11105	COG4463	regulation of RNA biosynthetic process
INV104_RS11110	COG1116	anion transmembrane transporter activity
INV104_RS11115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
INV104_RS11120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
INV104_RS11140	COG0305	Participates in initiation and elongation during chromosome replication
INV104_RS11160	COG1040	competence protein
INV104_RS11165	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
INV104_RS11170	COG1739	Uncharacterized protein family UPF0029
INV104_RS11205	COG3942	CHAP domain
INV104_RS11215	COG1792	Involved in formation and maintenance of cell shape
INV104_RS11220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
INV104_RS11225	COG1122	ATPase activity
INV104_RS11230	COG1122	ATPase activity
INV104_RS11235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
INV104_RS11245	COG0612	Peptidase, M16
INV104_RS11250	COG0612	Peptidase, M16
INV104_RS11255	COG2501	S4 domain
INV104_RS11265	COG0517	IMP dehydrogenase activity
INV104_RS11265	COG0516	GMP reductase activity
INV104_RS11270	COG0180	Tryptophanyl-tRNA synthetase
INV104_RS11275	COG0488	(ABC) transporter
INV104_RS11285	COG2801	Transposase and inactivated derivatives
INV104_RS11310	COG1511	domain protein
INV104_RS11355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
INV104_RS11360	COG1475	DNA binding
INV104_RS11395	COG0577	efflux transmembrane transporter activity
INV104_RS11395	COG1136	(ABC) transporter
INV104_RS11400	COG3335	DDE superfamily endonuclease