locus-tag	class	description
SPJ_RS00010	COG0592	DNA-directed DNA polymerase activity
SPJ_RS00020	COG0012	GTP binding
SPJ_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SPJ_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SPJ_RS00060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SPJ_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SPJ_RS00115	COG3335	DDE superfamily endonuclease
SPJ_RS00150	COG0582	viral genome integration into host DNA
SPJ_RS00155	COG0582	viral genome integration into host DNA
SPJ_RS00195	COG5632	N-Acetylmuramoyl-L-alanine amidase
SPJ_RS00195	COG5263	repeat protein
SPJ_RS00205	COG0756	dUTP diphosphatase activity
SPJ_RS00215	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SPJ_RS00235	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SPJ_RS00255	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SPJ_RS00255	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SPJ_RS00260	COG1832	CoA-binding protein
SPJ_RS00265	COG2855	membrane
SPJ_RS00270	COG0436	Aminotransferase
SPJ_RS00285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SPJ_RS00330	COG1388	LysM domain
SPJ_RS00330	COG1134	teichoic acid transport
SPJ_RS00345	COG2274	protein secretion by the type I secretion system
SPJ_RS00350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPJ_RS00365	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SPJ_RS00380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SPJ_RS00395	COG0151	Belongs to the GarS family
SPJ_RS00400	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SPJ_RS00415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SPJ_RS00420	COG3583	domain protein
SPJ_RS00420	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SPJ_RS00420	COG3064	Membrane
SPJ_RS00435	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS00440	COG3715	PTS system
SPJ_RS00445	COG3716	PTS system mannose fructose sorbose family IID component
SPJ_RS00455	COG2222	sugar isomerase
SPJ_RS00465	COG2514	catechol 2,3-dioxygenase activity
SPJ_RS00470	COG1937	Protein conserved in bacteria
SPJ_RS00505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SPJ_RS00510	COG0569	domain protein
SPJ_RS00520	COG1215	transferase activity, transferring glycosyl groups
SPJ_RS00540	COG5002	protein histidine kinase activity
SPJ_RS00560	COG4209	transmembrane transport
SPJ_RS00565	COG0395	ABC-type sugar transport system, permease component
SPJ_RS00575	COG1653	transport
SPJ_RS00605	COG1695	Transcriptional regulator
SPJ_RS00630	COG0546	phosphoglycolate phosphatase activity
SPJ_RS00635	COG1760	l-serine dehydratase
SPJ_RS00640	COG1760	l-serine dehydratase
SPJ_RS00645	COG1388	LysM domain
SPJ_RS00645	COG1705	Flagellar rod assembly protein muramidase FlgJ
SPJ_RS00665	COG0577	efflux transmembrane transporter activity
SPJ_RS00665	COG1136	(ABC) transporter
SPJ_RS00670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS00690	COG2274	protein secretion by the type I secretion system
SPJ_RS00750	COG0494	nUDIX hydrolase
SPJ_RS00755	COG0445	tRNA wobble uridine modification
SPJ_RS00785	COG1214	PFAM Peptidase M22, glycoprotease
SPJ_RS00825	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS00860	COG1396	sequence-specific DNA binding
SPJ_RS00890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS00895	COG1464	Belongs to the NlpA lipoprotein family
SPJ_RS00900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SPJ_RS00905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SPJ_RS00925	COG2972	Histidine kinase
SPJ_RS00930	COG4753	response regulator
SPJ_RS00930	COG2207	Transcriptional regulator
SPJ_RS00940	COG1780	Probably involved in ribonucleotide reductase function
SPJ_RS00970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SPJ_RS00970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SPJ_RS00990	COG0519	Catalyzes the synthesis of GMP from XMP
SPJ_RS01015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SPJ_RS01020	COG0006	proline dipeptidase activity
SPJ_RS01025	COG1393	Belongs to the ArsC family
SPJ_RS01050	COG0285	dihydrofolate synthase activity
SPJ_RS01060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SPJ_RS01125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SPJ_RS01150	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SPJ_RS01190	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SPJ_RS01205	COG0201	protein transport
SPJ_RS01215	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SPJ_RS01220	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SPJ_RS01230	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SPJ_RS01235	COG0202	RNA polymerase activity
SPJ_RS01245	COG3830	Belongs to the UPF0237 family
SPJ_RS01270	COG3842	ATPase activity
SPJ_RS01290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SPJ_RS01295	COG1349	DNA-binding transcription factor activity
SPJ_RS01305	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPJ_RS01310	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS01315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS01320	COG1882	Formate acetyltransferase
SPJ_RS01365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SPJ_RS01370	COG4589	Belongs to the CDS family
SPJ_RS01375	COG0750	zinc metalloprotease
SPJ_RS01385	COG2723	6-phospho-beta-galactosidase activity
SPJ_RS01390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SPJ_RS01400	COG1523	belongs to the glycosyl hydrolase 13 family
SPJ_RS01420	COG2176	DNA-directed DNA polymerase activity
SPJ_RS01440	COG2309	aminopeptidase activity
SPJ_RS01445	COG2261	transglycosylase associated protein
SPJ_RS01450	COG1187	pseudouridine synthase activity
SPJ_RS01460	COG3579	cysteine-type endopeptidase activity
SPJ_RS01465	COG3716	PTS system mannose fructose sorbose family IID component
SPJ_RS01470	COG3715	PTS system
SPJ_RS01480	COG1064	alcohol dehydrogenase
SPJ_RS01485	COG0561	phosphatase activity
SPJ_RS01490	COG2252	PERMEase
SPJ_RS01500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SPJ_RS01505	COG0285	dihydrofolate synthase activity
SPJ_RS01515	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SPJ_RS01515	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SPJ_RS01530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SPJ_RS01555	COG0386	Belongs to the glutathione peroxidase family
SPJ_RS01560	COG5492	domain, Protein
SPJ_RS01585	COG1028	Short-chain dehydrogenase reductase Sdr
SPJ_RS01595	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SPJ_RS01600	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS01605	COG3715	PTS system
SPJ_RS01610	COG3716	PTS system mannose fructose sorbose family IID component
SPJ_RS01625	COG1609	Transcriptional regulator
SPJ_RS01650	COG4839	cell division protein FtsL
SPJ_RS01655	COG0768	penicillin binding
SPJ_RS01680	COG0366	Alpha amylase catalytic
SPJ_RS01720	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
SPJ_RS01735	COG1216	Glycosyl transferase, family 2
SPJ_RS01740	COG1442	glycosyl transferase family 8
SPJ_RS01740	COG1216	Glycosyl transferase, family 2
SPJ_RS01760	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
SPJ_RS01785	COG4166	transmembrane transport
SPJ_RS01790	COG0366	Alpha amylase catalytic
SPJ_RS01795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPJ_RS01820	COG0116	Belongs to the methyltransferase superfamily
SPJ_RS01830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SPJ_RS01835	COG0745	RESPONSE REGULATOR receiver
SPJ_RS01885	COG4585	Histidine kinase
SPJ_RS01890	COG2197	response regulator
SPJ_RS01925	COG2801	Transposase and inactivated derivatives
SPJ_RS01945	COG2213	PTS system mannitol-specific
SPJ_RS01950	COG3711	transcriptional antiterminator
SPJ_RS01955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPJ_RS01980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SPJ_RS01985	COG0681	Belongs to the peptidase S26 family
SPJ_RS02010	COG1115	amino acid carrier protein
SPJ_RS02035	COG0527	aspartate kinase activity
SPJ_RS02040	COG1024	Enoyl-CoA hydratase
SPJ_RS02045	COG1846	Transcriptional regulator
SPJ_RS02055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SPJ_RS02065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SPJ_RS02070	COG1028	Short-chain dehydrogenase reductase Sdr
SPJ_RS02075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SPJ_RS02090	COG0439	Biotin carboxylase
SPJ_RS02095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SPJ_RS02145	COG1442	glycosyl transferase family 8
SPJ_RS02150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SPJ_RS02160	COG1461	Dihydroxyacetone kinase
SPJ_RS02165	COG0028	Belongs to the TPP enzyme family
SPJ_RS02170	COG0440	acetolactate synthase activity
SPJ_RS02190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SPJ_RS02205	COG0765	amino acid transport
SPJ_RS02230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SPJ_RS02235	COG1882	Formate acetyltransferase
SPJ_RS02275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SPJ_RS02280	COG0569	domain protein
SPJ_RS02300	COG1122	ATPase activity
SPJ_RS02315	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SPJ_RS02320	COG0671	phosphoesterase, PA-phosphatase related
SPJ_RS02330	COG1247	-acetyltransferase
SPJ_RS02345	COG0504	CTP synthase activity
SPJ_RS02370	COG0789	Transcriptional regulator
SPJ_RS02375	COG0174	glutamine synthetase
SPJ_RS02385	COG0732	type I restriction modification DNA specificity domain
SPJ_RS02395	COG4974	Belongs to the 'phage' integrase family
SPJ_RS02445	COG0484	heat shock protein binding
SPJ_RS02460	COG0537	adenosine 5'-monophosphoramidase activity
SPJ_RS02465	COG1131	(ABC) transporter
SPJ_RS02490	COG3290	protein histidine kinase activity
SPJ_RS02500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPJ_RS02505	COG2274	protein secretion by the type I secretion system
SPJ_RS02510	COG2274	protein secretion by the type I secretion system
SPJ_RS02565	COG1266	CAAX protease self-immunity
SPJ_RS02585	COG0195	Participates in both transcription termination and antitermination
SPJ_RS02590	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SPJ_RS02650	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SPJ_RS02660	COG0525	valine-tRNA ligase activity
SPJ_RS02690	COG0456	acetyltransferase
SPJ_RS02695	COG0072	phenylalanine-tRNA ligase activity
SPJ_RS02695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPJ_RS02710	COG3620	sequence-specific DNA binding
SPJ_RS02715	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
SPJ_RS02730	COG1045	serine acetyltransferase
SPJ_RS02740	COG0215	cysteine-tRNA ligase activity
SPJ_RS02745	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SPJ_RS02770	COG0577	efflux transmembrane transporter activity
SPJ_RS02775	COG1136	(ABC) transporter
SPJ_RS02780	COG0577	efflux transmembrane transporter activity
SPJ_RS02785	COG0745	RESPONSE REGULATOR receiver
SPJ_RS02790	COG5002	protein histidine kinase activity
SPJ_RS02795	COG0191	fructose-bisphosphate aldolase activity
SPJ_RS02800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SPJ_RS02805	COG0765	amino acid transport
SPJ_RS02810	COG0765	amino acid transport
SPJ_RS02815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS02825	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SPJ_RS02825	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SPJ_RS02865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS02880	COG1573	uracil-dna glycosylase
SPJ_RS02890	COG1114	Component of the transport system for branched-chain amino acids
SPJ_RS02895	COG1363	Peptidase, m42
SPJ_RS02945	COG4555	ABC transporter
SPJ_RS02975	COG1404	Belongs to the peptidase S8 family
SPJ_RS02990	COG3775	system Galactitol-specific IIC component
SPJ_RS03000	COG3250	beta-galactosidase activity
SPJ_RS03020	COG1242	4 iron, 4 sulfur cluster binding
SPJ_RS03025	COG1242	4 iron, 4 sulfur cluster binding
SPJ_RS03030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SPJ_RS03050	COG0785	Cytochrome C biogenesis protein
SPJ_RS03055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPJ_RS03060	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPJ_RS03060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPJ_RS03065	COG2207	Transcriptional regulator
SPJ_RS03065	COG4753	response regulator
SPJ_RS03070	COG2972	Histidine kinase
SPJ_RS03085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SPJ_RS03095	COG5263	repeat protein
SPJ_RS03095	COG4193	domain, Protein
SPJ_RS03100	COG1940	carbohydrate kinase activity
SPJ_RS03120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SPJ_RS03125	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SPJ_RS03135	COG0300	oxidoreductase activity
SPJ_RS03150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SPJ_RS03160	COG1187	pseudouridine synthase activity
SPJ_RS03165	COG1217	gtp-binding protein TYPA
SPJ_RS03185	COG1136	(ABC) transporter
SPJ_RS03200	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SPJ_RS03210	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SPJ_RS03235	COG1131	(ABC) transporter
SPJ_RS03240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS03250	COG1126	abc transporter atp-binding protein
SPJ_RS03255	COG0765	amino acid transport
SPJ_RS03260	COG0765	amino acid transport
SPJ_RS03265	COG1304	FMN binding
SPJ_RS03275	COG1304	FMN binding
SPJ_RS03290	COG0352	thiamine-phosphate diphosphorylase activity
SPJ_RS03300	COG4172	Belongs to the ABC transporter superfamily
SPJ_RS03310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SPJ_RS03325	COG0352	thiamine-phosphate diphosphorylase activity
SPJ_RS03345	COG2217	Heavy metal translocating P-type atpase
SPJ_RS03350	COG0028	Belongs to the TPP enzyme family
SPJ_RS03375	COG2723	6-phospho-beta-galactosidase activity
SPJ_RS03380	COG1482	cell wall glycoprotein biosynthetic process
SPJ_RS03385	COG0733	neurotransmitter:sodium symporter activity
SPJ_RS03400	COG2081	HI0933 family
SPJ_RS03405	COG1307	EDD domain protein, DegV family
SPJ_RS03415	COG2131	deaminase
SPJ_RS03420	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SPJ_RS03460	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SPJ_RS03460	COG0617	tRNA 3'-terminal CCA addition
SPJ_RS03460	COG0517	IMP dehydrogenase activity
SPJ_RS03465	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SPJ_RS03470	COG2884	Cell division ATP-binding protein ftsE
SPJ_RS03475	COG2177	Part of the ABC transporter FtsEX involved in
SPJ_RS03480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS03480	COG1263	PTS System
SPJ_RS03480	COG2190	(PTS) system
SPJ_RS03490	COG0513	Belongs to the DEAD box helicase family
SPJ_RS03500	COG0167	dihydroorotate dehydrogenase activity
SPJ_RS03510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SPJ_RS03515	COG4470	Protein conserved in bacteria
SPJ_RS03530	COG0488	(ABC) transporter
SPJ_RS03555	COG1837	Belongs to the UPF0109 family
SPJ_RS03575	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SPJ_RS03575	COG1328	CTP reductase activity
SPJ_RS03585	COG4443	Transcriptional Coactivator p15 (PC4)
SPJ_RS03595	COG1268	BioY protein
SPJ_RS03610	COG1136	(ABC) transporter
SPJ_RS03610	COG0577	efflux transmembrane transporter activity
SPJ_RS03620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPJ_RS03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPJ_RS03630	COG1136	(ABC) transporter
SPJ_RS03635	COG0577	efflux transmembrane transporter activity
SPJ_RS03640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPJ_RS03640	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPJ_RS03660	COG4989	oxidoreductase activity
SPJ_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
SPJ_RS03705	COG0745	RESPONSE REGULATOR receiver
SPJ_RS03710	COG5002	protein histidine kinase activity
SPJ_RS03730	COG0772	Belongs to the SEDS family
SPJ_RS03735	COG0693	protein deglycase activity
SPJ_RS03745	COG0187	DNA topoisomerase II activity
SPJ_RS03765	COG0494	nUDIX hydrolase
SPJ_RS03780	COG0542	response to heat
SPJ_RS03785	COG4703	Protein of unknown function (DUF1797)
SPJ_RS03790	COG0765	amino acid transport
SPJ_RS03795	COG1126	abc transporter atp-binding protein
SPJ_RS03800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SPJ_RS03810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SPJ_RS03830	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SPJ_RS03875	COG2813	Specifically methylates the guanine in position
SPJ_RS03880	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SPJ_RS03890	COG0295	cytidine deaminase activity
SPJ_RS03895	COG1744	ABC transporter substrate-binding protein PnrA-like
SPJ_RS03900	COG3845	ABC transporter
SPJ_RS03905	COG4603	Belongs to the binding-protein-dependent transport system permease family
SPJ_RS03910	COG1079	Belongs to the binding-protein-dependent transport system permease family
SPJ_RS03925	COG2801	Transposase and inactivated derivatives
SPJ_RS03935	COG0187	DNA topoisomerase II activity
SPJ_RS03945	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SPJ_RS03950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SPJ_RS03955	COG4166	transmembrane transport
SPJ_RS03990	COG0539	negative regulation of cytoplasmic translation
SPJ_RS04010	COG1956	GAF domain-containing protein
SPJ_RS04015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SPJ_RS04030	COG0719	Fe-S assembly protein
SPJ_RS04035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SPJ_RS04045	COG0719	Fe-S assembly protein
SPJ_RS04055	COG1686	Belongs to the peptidase S11 family
SPJ_RS04060	COG0628	permease
SPJ_RS04070	COG1349	DNA-binding transcription factor activity
SPJ_RS04075	COG1105	Belongs to the carbohydrate kinase PfkB family
SPJ_RS04080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPJ_RS04080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPJ_RS04080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPJ_RS04085	COG0697	spore germination
SPJ_RS04085	COG1674	ftsk spoiiie
SPJ_RS04095	COG1104	cysteine desulfurase activity
SPJ_RS04155	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SPJ_RS04160	COG1438	arginine binding
SPJ_RS04180	COG0469	pyruvate kinase activity
SPJ_RS04215	COG3689	TIGRFAM TIGR03943 family protein
SPJ_RS04220	COG0701	Predicted permease
SPJ_RS04235	COG2183	response to ionizing radiation
SPJ_RS04260	COG1136	(ABC) transporter
SPJ_RS04265	COG0577	efflux transmembrane transporter activity
SPJ_RS04280	COG1982	Orn Lys Arg decarboxylase major
SPJ_RS04295	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SPJ_RS04315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SPJ_RS04320	COG0561	phosphatase activity
SPJ_RS04340	COG0583	DNA-binding transcription factor activity
SPJ_RS04345	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SPJ_RS04350	COG0564	pseudouridine synthase activity
SPJ_RS04355	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SPJ_RS04370	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SPJ_RS04380	COG0470	DNA polymerase III
SPJ_RS04425	COG0528	UMP kinase activity
SPJ_RS04435	COG2996	Protein conserved in bacteria
SPJ_RS04445	COG1702	phosphate starvation-inducible protein PhoH
SPJ_RS04460	COG0686	Belongs to the AlaDH PNT family
SPJ_RS04465	COG0686	Belongs to the AlaDH PNT family
SPJ_RS04470	COG0686	Belongs to the AlaDH PNT family
SPJ_RS04475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SPJ_RS04480	COG1596	polysaccharide export
SPJ_RS04480	COG1555	photosystem II stabilization
SPJ_RS04485	COG2333	competence protein COMEC
SPJ_RS04485	COG0658	competence protein
SPJ_RS04495	COG1131	(ABC) transporter
SPJ_RS04525	COG0543	2 iron, 2 sulfur cluster binding
SPJ_RS04530	COG0167	dihydroorotate dehydrogenase activity
SPJ_RS04535	COG4193	domain, Protein
SPJ_RS04535	COG5263	repeat protein
SPJ_RS04540	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SPJ_RS04550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SPJ_RS04560	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SPJ_RS04565	COG0237	dephospho-CoA kinase activity
SPJ_RS04570	COG2814	Major facilitator Superfamily
SPJ_RS04585	COG0557	exoribonuclease II activity
SPJ_RS04595	COG3615	Tellurite resistance protein tehB
SPJ_RS04595	COG0500	methyltransferase
SPJ_RS04610	COG4122	O-methyltransferase activity
SPJ_RS04620	COG2801	Transposase and inactivated derivatives
SPJ_RS04635	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SPJ_RS04655	COG0494	nUDIX hydrolase
SPJ_RS04665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SPJ_RS04675	COG2176	DNA-directed DNA polymerase activity
SPJ_RS04680	COG0584	glycerophosphoryl diester phosphodiesterase
SPJ_RS04700	COG0785	Cytochrome C biogenesis protein
SPJ_RS04705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPJ_RS04710	COG0531	amino acid
SPJ_RS04715	COG3443	Belongs to the bacterial solute-binding protein 9 family
SPJ_RS04715	COG0803	Belongs to the bacterial solute-binding protein 9 family
SPJ_RS04755	COG1970	mechanosensitive ion channel activity
SPJ_RS04765	COG4708	membrane
SPJ_RS04775	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SPJ_RS04785	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
SPJ_RS04790	COG1942	4-Oxalocrotonate Tautomerase
SPJ_RS04795	COG1435	thymidine kinase activity
SPJ_RS04805	COG2890	protein-(glutamine-N5) methyltransferase activity
SPJ_RS04830	COG0741	lytic transglycosylase activity
SPJ_RS04840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SPJ_RS04860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPJ_RS04865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPJ_RS04920	COG1597	lipid kinase activity
SPJ_RS04925	COG0366	Alpha amylase catalytic
SPJ_RS04940	COG1396	sequence-specific DNA binding
SPJ_RS04945	COG0542	response to heat
SPJ_RS04950	COG0613	PHP domain protein
SPJ_RS04955	COG1196	nuclear chromosome segregation
SPJ_RS04970	COG3843	relaxase mobilization nuclease domain protein
SPJ_RS05005	COG1131	(ABC) transporter
SPJ_RS05025	COG0772	Belongs to the SEDS family
SPJ_RS05030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SPJ_RS05050	COG0358	DNA primase activity
SPJ_RS05055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SPJ_RS05060	COG2151	metal-sulfur cluster biosynthetic enzyme
SPJ_RS05065	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS05070	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS05095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SPJ_RS05105	COG4109	DRTGG domain
SPJ_RS05110	COG0024	Methionine aminopeptidase
SPJ_RS05130	COG0210	DNA helicase
SPJ_RS05140	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SPJ_RS05160	COG1104	cysteine desulfurase activity
SPJ_RS05165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SPJ_RS05175	COG2357	RelA SpoT domain protein
SPJ_RS05185	COG0564	pseudouridine synthase activity
SPJ_RS05190	COG0280	phosphate acetyltransferase
SPJ_RS05240	COG0196	riboflavin kinase activity
SPJ_RS05245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SPJ_RS05250	COG1307	EDD domain protein, DegV family
SPJ_RS05260	COG0488	(ABC) transporter
SPJ_RS05270	COG2814	Major facilitator Superfamily
SPJ_RS05280	COG1523	belongs to the glycosyl hydrolase 13 family
SPJ_RS05290	COG1012	belongs to the aldehyde dehydrogenase family
SPJ_RS05295	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SPJ_RS05305	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SPJ_RS05315	COG0560	Phosphoserine phosphatase
SPJ_RS05320	COG0560	Phosphoserine phosphatase
SPJ_RS05340	COG0582	viral genome integration into host DNA
SPJ_RS05365	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SPJ_RS05365	COG3583	domain protein
SPJ_RS05370	COG3064	Membrane
SPJ_RS05375	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SPJ_RS05395	COG0095	Lipoate-protein ligase
SPJ_RS05400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPJ_RS05405	COG0508	dehydrogenase complex catalyzes the overall conversion of
SPJ_RS05410	COG0022	dehydrogenase e1 component
SPJ_RS05415	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SPJ_RS05420	COG0534	Mate efflux family protein
SPJ_RS05430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SPJ_RS05435	COG1051	belongs to the nudix hydrolase family
SPJ_RS05450	COG1011	Hydrolase
SPJ_RS05470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPJ_RS05475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SPJ_RS05480	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SPJ_RS05485	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SPJ_RS05510	COG3711	transcriptional antiterminator
SPJ_RS05515	COG3684	Belongs to the aldolase LacD family
SPJ_RS05570	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SPJ_RS05575	COG0497	DNA recombination
SPJ_RS05580	COG1438	arginine binding
SPJ_RS05585	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SPJ_RS05620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SPJ_RS05640	COG3764	Sortase (surface protein transpeptidase)
SPJ_RS05645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SPJ_RS05655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SPJ_RS05670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SPJ_RS05675	COG5002	protein histidine kinase activity
SPJ_RS05680	COG0745	RESPONSE REGULATOR receiver
SPJ_RS05685	COG1194	a g-specific adenine glycosylase
SPJ_RS05700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SPJ_RS05705	COG4684	Psort location CytoplasmicMembrane, score
SPJ_RS05715	COG1827	regulation of RNA biosynthetic process
SPJ_RS05745	COG0765	amino acid transport
SPJ_RS05750	COG1126	abc transporter atp-binding protein
SPJ_RS05755	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SPJ_RS05760	COG0552	protein localization to endoplasmic reticulum
SPJ_RS05765	COG0561	phosphatase activity
SPJ_RS05770	COG0561	phosphatase activity
SPJ_RS05775	COG1196	nuclear chromosome segregation
SPJ_RS05800	COG1401	restriction endodeoxyribonuclease activity
SPJ_RS05815	COG0066	3-isopropylmalate dehydratase activity
SPJ_RS05825	COG0473	3-isopropylmalate dehydrogenase activity
SPJ_RS05845	COG3142	Participates in the control of copper homeostasis
SPJ_RS05850	COG2832	Protein of unknown function (DUF454)
SPJ_RS05855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SPJ_RS05865	COG0758	DNA mediated transformation
SPJ_RS05870	COG4750	Nucleotidyl transferase
SPJ_RS05885	COG1063	alcohol dehydrogenase
SPJ_RS05900	COG3475	LICD family
SPJ_RS05905	COG3475	LICD family
SPJ_RS05915	COG0505	Belongs to the CarA family
SPJ_RS05930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SPJ_RS05950	COG0488	(ABC) transporter
SPJ_RS05960	COG1704	LemA family
SPJ_RS05975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SPJ_RS05990	COG1078	dGTPase activity
SPJ_RS06015	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SPJ_RS06020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SPJ_RS06025	COG0077	Prephenate dehydratase
SPJ_RS06025	COG1605	Chorismate mutase
SPJ_RS06030	COG0716	FMN binding
SPJ_RS06035	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SPJ_RS06055	COG3335	DDE superfamily endonuclease
SPJ_RS06065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SPJ_RS06150	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
SPJ_RS06155	COG1269	ATP hydrolysis coupled proton transport
SPJ_RS06170	COG0673	inositol 2-dehydrogenase activity
SPJ_RS06175	COG4409	exo-alpha-(2->6)-sialidase activity
SPJ_RS06185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
SPJ_RS06190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SPJ_RS06195	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
SPJ_RS06200	COG1737	Transcriptional regulator
SPJ_RS06235	COG0402	S-adenosylhomocysteine deaminase activity
SPJ_RS06245	COG1132	(ABC) transporter
SPJ_RS06250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPJ_RS06250	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPJ_RS06285	COG1215	transferase activity, transferring glycosyl groups
SPJ_RS06295	COG3475	LICD family
SPJ_RS06305	COG0077	Prephenate dehydratase
SPJ_RS06310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SPJ_RS06325	COG0287	Prephenate dehydrogenase
SPJ_RS06350	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SPJ_RS06360	COG4555	ABC transporter
SPJ_RS06400	COG3842	ATPase activity
SPJ_RS06415	COG3527	Alpha-acetolactate decarboxylase
SPJ_RS06420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SPJ_RS06430	COG0704	Plays a role in the regulation of phosphate uptake
SPJ_RS06435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPJ_RS06440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPJ_RS06445	COG0581	inorganic phosphate transmembrane transporter activity
SPJ_RS06450	COG0573	inorganic phosphate transmembrane transporter activity
SPJ_RS06455	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SPJ_RS06460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SPJ_RS06460	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SPJ_RS06465	COG0483	inositol monophosphate 1-phosphatase activity
SPJ_RS06475	COG1393	Belongs to the ArsC family
SPJ_RS06485	COG0647	UMP catabolic process
SPJ_RS06495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SPJ_RS06545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SPJ_RS06555	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SPJ_RS06580	COG0826	peptidase U32
SPJ_RS06590	COG0826	peptidase U32
SPJ_RS06620	COG1132	(ABC) transporter
SPJ_RS06635	COG1129	ABC transporter
SPJ_RS06675	COG2188	Transcriptional regulator
SPJ_RS06680	COG0697	spore germination
SPJ_RS06685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SPJ_RS06700	COG0561	phosphatase activity
SPJ_RS06730	COG0492	ferredoxin-NADP+ reductase activity
SPJ_RS06740	COG1126	abc transporter atp-binding protein
SPJ_RS06750	COG1393	Belongs to the ArsC family
SPJ_RS06770	COG1272	protein, Hemolysin III
SPJ_RS06800	COG1053	succinate dehydrogenase
SPJ_RS06800	COG0431	NADPH-dependent FMN reductase
SPJ_RS06800	COG3976	FMN-binding domain protein
SPJ_RS06825	COG0656	L-ascorbic acid biosynthetic process
SPJ_RS06830	COG0726	polysaccharide deacetylase
SPJ_RS06855	COG3335	DDE superfamily endonuclease
SPJ_RS06890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPJ_RS06930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SPJ_RS06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPJ_RS06945	COG1126	abc transporter atp-binding protein
SPJ_RS06955	COG0457	Tetratricopeptide repeat
SPJ_RS06960	COG0628	permease
SPJ_RS06965	COG2706	6-phosphogluconolactonase activity
SPJ_RS07070	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SPJ_RS07075	COG0626	cystathionine gamma-synthase activity
SPJ_RS07080	COG1132	(ABC) transporter
SPJ_RS07085	COG1132	(ABC) transporter
SPJ_RS07095	COG4166	transmembrane transport
SPJ_RS07100	COG2244	polysaccharide biosynthetic process
SPJ_RS07105	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SPJ_RS07130	COG2827	Endonuclease containing a URI domain
SPJ_RS07135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SPJ_RS07140	COG1098	S1 RNA binding domain
SPJ_RS07150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SPJ_RS07155	COG0629	single-stranded DNA binding
SPJ_RS07165	COG0017	Asparaginyl-tRNA synthetase
SPJ_RS07175	COG0436	Aminotransferase
SPJ_RS07200	COG3711	transcriptional antiterminator
SPJ_RS07220	COG0242	peptide deformylase activity
SPJ_RS07225	COG0625	glutathione transferase activity
SPJ_RS07235	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SPJ_RS07240	COG0488	(ABC) transporter
SPJ_RS07245	COG0617	tRNA 3'-terminal CCA addition
SPJ_RS07255	COG1307	EDD domain protein, DegV family
SPJ_RS07275	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SPJ_RS07285	COG0492	ferredoxin-NADP+ reductase activity
SPJ_RS07295	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SPJ_RS07305	COG0251	oxidation-reduction process
SPJ_RS07325	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SPJ_RS07335	COG5263	repeat protein
SPJ_RS07335	COG4193	domain, Protein
SPJ_RS07345	COG3935	DnaD domain protein
SPJ_RS07360	COG2226	methyltransferase
SPJ_RS07370	COG3842	ATPase activity
SPJ_RS07380	COG1335	isochorismatase
SPJ_RS07390	COG0513	Belongs to the DEAD box helicase family
SPJ_RS07395	COG2223	nitrite transmembrane transporter activity
SPJ_RS07400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPJ_RS07405	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SPJ_RS07410	COG3442	glutamine amidotransferase
SPJ_RS07415	COG0006	proline dipeptidase activity
SPJ_RS07420	COG2801	Transposase and inactivated derivatives
SPJ_RS07435	COG4720	Psort location CytoplasmicMembrane, score
SPJ_RS07440	COG0351	phosphomethylpyrimidine kinase
SPJ_RS07465	COG2824	Alkylphosphonate utilization operon protein PhnA
SPJ_RS07485	COG0463	Glycosyl transferase, family 2
SPJ_RS07490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SPJ_RS07495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SPJ_RS07500	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SPJ_RS07505	COG2384	SAM-dependent methyltransferase
SPJ_RS07510	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SPJ_RS07515	COG0204	Acyl-transferase
SPJ_RS07530	COG2910	NAD(P)H-binding
SPJ_RS07550	COG5002	protein histidine kinase activity
SPJ_RS07555	COG0745	RESPONSE REGULATOR receiver
SPJ_RS07570	COG1959	2 iron, 2 sulfur cluster binding
SPJ_RS07640	COG3590	peptidase
SPJ_RS07660	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SPJ_RS07675	COG0577	efflux transmembrane transporter activity
SPJ_RS07675	COG1136	(ABC) transporter
SPJ_RS07720	COG3599	regulation of cell shape
SPJ_RS07740	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SPJ_RS07760	COG1051	belongs to the nudix hydrolase family
SPJ_RS07765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SPJ_RS07780	COG0768	penicillin binding
SPJ_RS07795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SPJ_RS07815	COG2731	YhcH YjgK YiaL family protein
SPJ_RS07820	COG0395	ABC-type sugar transport system, permease component
SPJ_RS07825	COG1175	transmembrane transport
SPJ_RS07835	COG1263	PTS System
SPJ_RS07835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS07835	COG2190	(PTS) system
SPJ_RS07845	COG0673	inositol 2-dehydrogenase activity
SPJ_RS07850	COG4409	exo-alpha-(2->6)-sialidase activity
SPJ_RS07860	COG1175	transmembrane transport
SPJ_RS07865	COG1653	transport
SPJ_RS07890	COG3458	cephalosporin-C deacetylase activity
SPJ_RS07895	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SPJ_RS07910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SPJ_RS07915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SPJ_RS07920	COG0653	protein targeting
SPJ_RS07930	COG1131	(ABC) transporter
SPJ_RS07970	COG0778	Nitroreductase
SPJ_RS07975	COG1484	DNA-dependent DNA replication
SPJ_RS07990	COG1725	Transcriptional regulator
SPJ_RS07995	COG1131	(ABC) transporter
SPJ_RS08005	COG1668	transmembrane transport
SPJ_RS08010	COG4152	abc transporter atp-binding protein
SPJ_RS08030	COG1940	carbohydrate kinase activity
SPJ_RS08035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS08035	COG2190	(PTS) system
SPJ_RS08035	COG1263	PTS System
SPJ_RS08045	COG1621	beta-fructofuranosidase activity
SPJ_RS08050	COG1609	Transcriptional regulator
SPJ_RS08060	COG3425	synthase
SPJ_RS08090	COG0515	serine threonine protein kinase
SPJ_RS08090	COG2815	serine threonine protein kinase
SPJ_RS08095	COG0631	protein serine/threonine phosphatase activity
SPJ_RS08100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SPJ_RS08100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SPJ_RS08110	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SPJ_RS08120	COG0194	GDP metabolic process
SPJ_RS08130	COG4115	mRNA cleavage
SPJ_RS08145	COG2226	methyltransferase
SPJ_RS08150	COG0799	negative regulation of ribosome biogenesis
SPJ_RS08160	COG1713	HD superfamily hydrolase involved in NAD metabolism
SPJ_RS08165	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SPJ_RS08170	COG1534	Rna-binding protein
SPJ_RS08175	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SPJ_RS08190	COG0668	transmembrane transport
SPJ_RS08215	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS08220	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS08225	COG0653	protein targeting
SPJ_RS08245	COG0201	protein transport
SPJ_RS08250	COG1215	transferase activity, transferring glycosyl groups
SPJ_RS08255	COG1442	glycosyl transferase family 8
SPJ_RS08260	COG1442	glycosyl transferase family 8
SPJ_RS08265	COG1442	glycosyl transferase family 8
SPJ_RS08270	COG0438	transferase activity, transferring glycosyl groups
SPJ_RS08275	COG1216	Glycosyl transferase, family 2
SPJ_RS08275	COG1442	glycosyl transferase family 8
SPJ_RS08280	COG1442	glycosyl transferase family 8
SPJ_RS08285	COG1216	Glycosyl transferase, family 2
SPJ_RS08285	COG1442	glycosyl transferase family 8
SPJ_RS08310	COG3118	belongs to the thioredoxin family
SPJ_RS08315	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SPJ_RS08325	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPJ_RS08340	COG1164	Oligoendopeptidase f
SPJ_RS08345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SPJ_RS08405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SPJ_RS08415	COG1621	beta-fructofuranosidase activity
SPJ_RS08420	COG1653	transport
SPJ_RS08425	COG0395	ABC-type sugar transport system, permease component
SPJ_RS08430	COG4209	transmembrane transport
SPJ_RS08440	COG3711	transcriptional antiterminator
SPJ_RS08465	COG3237	CsbD-like
SPJ_RS08480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
SPJ_RS08490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS08495	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPJ_RS08500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS08510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS08515	COG1940	carbohydrate kinase activity
SPJ_RS08515	COG1846	Transcriptional regulator
SPJ_RS08525	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SPJ_RS08565	COG0512	Glutamine amidotransferase of anthranilate synthase
SPJ_RS08570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SPJ_RS08595	COG1285	pathogenesis
SPJ_RS08600	COG1178	ABC-type Fe3 transport system permease component
SPJ_RS08620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SPJ_RS08625	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SPJ_RS08630	COG0704	Plays a role in the regulation of phosphate uptake
SPJ_RS08645	COG5434	Belongs to the glycosyl hydrolase 28 family
SPJ_RS08660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SPJ_RS08665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SPJ_RS08670	COG1132	(ABC) transporter
SPJ_RS08675	COG1132	(ABC) transporter
SPJ_RS08700	COG0708	Exodeoxyribonuclease III
SPJ_RS08720	COG2233	PERMEase
SPJ_RS08745	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SPJ_RS08750	COG1609	Transcriptional regulator
SPJ_RS08755	COG1063	alcohol dehydrogenase
SPJ_RS08760	COG0789	Transcriptional regulator
SPJ_RS08765	COG1230	cation diffusion facilitator family transporter
SPJ_RS08775	COG3201	nicotinamide mononucleotide transporter
SPJ_RS08780	COG1174	glycine betaine transport
SPJ_RS08805	COG1363	Peptidase, m42
SPJ_RS08820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPJ_RS08825	COG4605	iron ion homeostasis
SPJ_RS08830	COG4604	ABC transporter, ATP-binding protein
SPJ_RS08835	COG4607	ABC-type enterochelin transport system periplasmic component
SPJ_RS08845	COG1187	pseudouridine synthase activity
SPJ_RS08865	COG0517	IMP dehydrogenase activity
SPJ_RS08875	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SPJ_RS08890	COG0366	Alpha amylase catalytic
SPJ_RS08895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS08895	COG1263	PTS System
SPJ_RS08900	COG2188	Transcriptional regulator
SPJ_RS08905	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SPJ_RS08910	COG4120	Belongs to the binding-protein-dependent transport system permease family
SPJ_RS08920	COG4608	Belongs to the ABC transporter superfamily
SPJ_RS08925	COG0444	Belongs to the ABC transporter superfamily
SPJ_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SPJ_RS08935	COG0601	transmembrane transport
SPJ_RS08940	COG4166	transmembrane transport
SPJ_RS08950	COG0366	Alpha amylase catalytic
SPJ_RS08960	COG0395	ABC-type sugar transport system, permease component
SPJ_RS08965	COG1175	transmembrane transport
SPJ_RS08970	COG1653	transport
SPJ_RS08975	COG3345	alpha-galactosidase
SPJ_RS08980	COG2207	Transcriptional regulator
SPJ_RS08985	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SPJ_RS08985	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SPJ_RS09110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SPJ_RS09160	COG5263	repeat protein
SPJ_RS09160	COG5632	N-Acetylmuramoyl-L-alanine amidase
SPJ_RS09270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
SPJ_RS09350	COG0629	single-stranded DNA binding
SPJ_RS09445	COG4221	oxidoreductase activity
SPJ_RS09450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPJ_RS09455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPJ_RS09490	COG1132	(ABC) transporter
SPJ_RS09495	COG1132	(ABC) transporter
SPJ_RS09580	COG5263	repeat protein
SPJ_RS09580	COG5632	N-Acetylmuramoyl-L-alanine amidase
SPJ_RS09600	COG1316	TRANSCRIPTIONal
SPJ_RS09610	COG0802	atpase or kinase
SPJ_RS09670	COG0577	efflux transmembrane transporter activity
SPJ_RS09670	COG1136	(ABC) transporter
SPJ_RS09700	COG1253	flavin adenine dinucleotide binding
SPJ_RS09715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SPJ_RS09725	COG3480	Lon protease (S16) C-terminal proteolytic domain
SPJ_RS09735	COG0742	ribosomal rna small subunit methyltransferase
SPJ_RS09755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SPJ_RS09760	COG1254	Belongs to the acylphosphatase family
SPJ_RS09770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SPJ_RS09780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SPJ_RS09795	COG1564	THIamine pyrophosphokinase
SPJ_RS09805	COG1162	GTPase activity
SPJ_RS09840	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SPJ_RS09845	COG0084	hydrolase, TatD family'
SPJ_RS09860	COG0436	Aminotransferase
SPJ_RS09870	COG0589	response to stress
SPJ_RS09875	COG0561	phosphatase activity
SPJ_RS09880	COG0252	asparaginase activity
SPJ_RS09890	COG1609	Transcriptional regulator
SPJ_RS09895	COG2197	response regulator
SPJ_RS09900	COG4585	Histidine kinase
SPJ_RS09905	COG0842	Transport permease protein
SPJ_RS09910	COG1131	(ABC) transporter
SPJ_RS10010	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SPJ_RS10015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPJ_RS10020	COG0564	pseudouridine synthase activity
SPJ_RS10030	COG0577	efflux transmembrane transporter activity
SPJ_RS10045	COG0157	Belongs to the NadC ModD family
SPJ_RS10055	COG4133	protoheme IX ABC transporter activity
SPJ_RS10060	COG2188	Transcriptional regulator
SPJ_RS10065	COG2723	6-phospho-beta-galactosidase activity
SPJ_RS10070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPJ_RS10080	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPJ_RS10085	COG1012	belongs to the aldehyde dehydrogenase family
SPJ_RS10085	COG1454	alcohol dehydrogenase
SPJ_RS10095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SPJ_RS10105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SPJ_RS10125	COG3623	hexulose-6-phosphate isomerase
SPJ_RS10135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPJ_RS10145	COG3037	sugar-specific permease SgaT UlaA
SPJ_RS10155	COG1847	R3H domain protein
SPJ_RS10160	COG0706	membrane insertase activity
SPJ_RS10180	COG2226	methyltransferase
SPJ_RS10205	COG4537	Required for transformation and DNA binding
SPJ_RS10210	COG1459	type II secretion system
SPJ_RS10215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SPJ_RS10225	COG1063	alcohol dehydrogenase
SPJ_RS10250	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SPJ_RS10255	COG3759	membrane
SPJ_RS10270	COG0131	Imidazoleglycerol-phosphate dehydratase
SPJ_RS10270	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SPJ_RS10275	COG0534	Mate efflux family protein
SPJ_RS10390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SPJ_RS10395	COG1132	(ABC) transporter
SPJ_RS10405	COG1132	(ABC) transporter
SPJ_RS10415	COG1438	arginine binding
SPJ_RS10435	COG0745	RESPONSE REGULATOR receiver
SPJ_RS10440	COG5002	protein histidine kinase activity
SPJ_RS10445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SPJ_RS10450	COG0573	inorganic phosphate transmembrane transporter activity
SPJ_RS10460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPJ_RS10465	COG0704	Plays a role in the regulation of phosphate uptake
SPJ_RS10485	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SPJ_RS10495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SPJ_RS10510	COG0697	spore germination
SPJ_RS10515	COG4499	WXG100 protein secretion system (Wss), protein YukC
SPJ_RS10515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPJ_RS10525	COG2217	Heavy metal translocating P-type atpase
SPJ_RS10535	COG2226	methyltransferase
SPJ_RS10555	COG0058	SHG alpha-glucan phosphorylase activity
SPJ_RS10560	COG1640	4-alpha-glucanotransferase
SPJ_RS10565	COG2182	Extracellular solute-binding protein
SPJ_RS10570	COG1175	transmembrane transport
SPJ_RS10575	COG3833	ABC-type maltose transport systems, permease component
SPJ_RS10580	COG5521	maltodextrose utilization protein MalA
SPJ_RS10585	COG1609	Transcriptional regulator
SPJ_RS10595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SPJ_RS10630	COG1476	TRANSCRIPTIONal
SPJ_RS10660	COG2151	metal-sulfur cluster biosynthetic enzyme
SPJ_RS10675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SPJ_RS10680	COG3959	Transketolase, thiamine diphosphate binding domain
SPJ_RS10695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPJ_RS10715	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SPJ_RS10755	COG0383	alpha-mannosidase activity
SPJ_RS10765	COG3537	Alpha-1,2-mannosidase
SPJ_RS10785	COG0549	Belongs to the carbamate kinase family
SPJ_RS10790	COG1288	antiporter activity
SPJ_RS10795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SPJ_RS10810	COG3064	Membrane
SPJ_RS10810	COG3583	domain protein
SPJ_RS10810	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SPJ_RS10820	COG1454	alcohol dehydrogenase
SPJ_RS10840	COG3716	PTS system mannose fructose sorbose family IID component
SPJ_RS10850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPJ_RS10870	COG1070	Carbohydrate kinase
SPJ_RS10880	COG3443	Belongs to the bacterial solute-binding protein 9 family
SPJ_RS10880	COG0803	Belongs to the bacterial solute-binding protein 9 family
SPJ_RS10885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SPJ_RS10890	COG1121	(ABC) transporter
SPJ_RS10895	COG1846	Transcriptional regulator
SPJ_RS10900	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
SPJ_RS10910	COG1696	Membrane protein involved in D-alanine export
SPJ_RS10925	COG2211	Major facilitator Superfamily
SPJ_RS10930	COG3344	reverse transcriptase
SPJ_RS10945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPJ_RS10950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SPJ_RS10970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SPJ_RS10980	COG1755	Isoprenylcysteine carboxyl methyltransferase
SPJ_RS10985	COG5002	protein histidine kinase activity
SPJ_RS10990	COG0745	RESPONSE REGULATOR receiver
SPJ_RS10995	COG0542	response to heat
SPJ_RS11000	COG4463	regulation of RNA biosynthetic process
SPJ_RS11005	COG1116	anion transmembrane transporter activity
SPJ_RS11010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SPJ_RS11015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SPJ_RS11035	COG0305	Participates in initiation and elongation during chromosome replication
SPJ_RS11055	COG1040	competence protein
SPJ_RS11060	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SPJ_RS11065	COG1739	Uncharacterized protein family UPF0029
SPJ_RS11080	COG3335	DDE superfamily endonuclease
SPJ_RS11100	COG3942	CHAP domain
SPJ_RS11110	COG1792	Involved in formation and maintenance of cell shape
SPJ_RS11115	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SPJ_RS11120	COG1122	ATPase activity
SPJ_RS11125	COG1122	ATPase activity
SPJ_RS11130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SPJ_RS11140	COG0612	Peptidase, M16
SPJ_RS11145	COG0612	Peptidase, M16
SPJ_RS11150	COG2501	S4 domain
SPJ_RS11160	COG0517	IMP dehydrogenase activity
SPJ_RS11160	COG0516	GMP reductase activity
SPJ_RS11165	COG0180	Tryptophanyl-tRNA synthetase
SPJ_RS11170	COG0488	(ABC) transporter
SPJ_RS11180	COG1511	domain protein
SPJ_RS11190	COG1511	domain protein
SPJ_RS11235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SPJ_RS11240	COG1475	DNA binding
SPJ_RS11310	COG2274	protein secretion by the type I secretion system