locus-tag	class	description
KK0981_RS00010	COG0592	DNA-directed DNA polymerase activity
KK0981_RS00020	COG0012	GTP binding
KK0981_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KK0981_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KK0981_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KK0981_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KK0981_RS00135	COG0582	viral genome integration into host DNA
KK0981_RS00190	COG0756	dUTP diphosphatase activity
KK0981_RS00200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KK0981_RS00220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KK0981_RS00245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KK0981_RS00245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KK0981_RS00250	COG1832	CoA-binding protein
KK0981_RS00260	COG2855	membrane
KK0981_RS00265	COG0436	Aminotransferase
KK0981_RS00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK0981_RS00305	COG2274	protein secretion by the type I secretion system
KK0981_RS00310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KK0981_RS00325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KK0981_RS00330	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KK0981_RS00340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KK0981_RS00355	COG0151	Belongs to the GarS family
KK0981_RS00370	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KK0981_RS00385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KK0981_RS00390	COG3583	domain protein
KK0981_RS00390	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KK0981_RS00390	COG3064	Membrane
KK0981_RS00410	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS00415	COG3715	PTS system
KK0981_RS00420	COG3716	PTS system mannose fructose sorbose family IID component
KK0981_RS00430	COG2222	sugar isomerase
KK0981_RS00440	COG2514	catechol 2,3-dioxygenase activity
KK0981_RS00445	COG1937	Protein conserved in bacteria
KK0981_RS00480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KK0981_RS00485	COG0569	domain protein
KK0981_RS00515	COG5002	protein histidine kinase activity
KK0981_RS00540	COG4209	transmembrane transport
KK0981_RS00545	COG0395	ABC-type sugar transport system, permease component
KK0981_RS00550	COG1653	transport
KK0981_RS00580	COG1695	Transcriptional regulator
KK0981_RS00605	COG0546	phosphoglycolate phosphatase activity
KK0981_RS00610	COG1760	l-serine dehydratase
KK0981_RS00615	COG1760	l-serine dehydratase
KK0981_RS00645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS00740	COG0445	tRNA wobble uridine modification
KK0981_RS00785	COG1214	PFAM Peptidase M22, glycoprotease
KK0981_RS00825	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS00860	COG1396	sequence-specific DNA binding
KK0981_RS00895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS00900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS00905	COG1464	Belongs to the NlpA lipoprotein family
KK0981_RS00910	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK0981_RS00915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KK0981_RS00935	COG2972	Histidine kinase
KK0981_RS00940	COG2207	Transcriptional regulator
KK0981_RS00940	COG4753	response regulator
KK0981_RS00950	COG1780	Probably involved in ribonucleotide reductase function
KK0981_RS00995	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KK0981_RS00995	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KK0981_RS01015	COG2818	Glycosylase
KK0981_RS01040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KK0981_RS01045	COG0006	proline dipeptidase activity
KK0981_RS01050	COG1393	Belongs to the ArsC family
KK0981_RS01080	COG0285	dihydrofolate synthase activity
KK0981_RS01090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KK0981_RS01155	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KK0981_RS01180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KK0981_RS01220	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KK0981_RS01235	COG0201	protein transport
KK0981_RS01245	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KK0981_RS01250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KK0981_RS01260	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KK0981_RS01265	COG0202	RNA polymerase activity
KK0981_RS01275	COG3830	Belongs to the UPF0237 family
KK0981_RS01300	COG3842	ATPase activity
KK0981_RS01315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KK0981_RS01320	COG1349	DNA-binding transcription factor activity
KK0981_RS01330	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK0981_RS01335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS01340	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS01345	COG1882	Formate acetyltransferase
KK0981_RS01360	COG0495	leucyl-tRNA aminoacylation
KK0981_RS01395	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KK0981_RS01400	COG4589	Belongs to the CDS family
KK0981_RS01405	COG0750	zinc metalloprotease
KK0981_RS01415	COG2723	6-phospho-beta-galactosidase activity
KK0981_RS01420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KK0981_RS01430	COG1523	belongs to the glycosyl hydrolase 13 family
KK0981_RS01460	COG2176	DNA-directed DNA polymerase activity
KK0981_RS01480	COG2309	aminopeptidase activity
KK0981_RS01490	COG1187	pseudouridine synthase activity
KK0981_RS01500	COG3579	cysteine-type endopeptidase activity
KK0981_RS01505	COG3716	PTS system mannose fructose sorbose family IID component
KK0981_RS01510	COG3715	PTS system
KK0981_RS01520	COG1064	alcohol dehydrogenase
KK0981_RS01530	COG0561	phosphatase activity
KK0981_RS01535	COG2252	PERMEase
KK0981_RS01545	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KK0981_RS01550	COG0285	dihydrofolate synthase activity
KK0981_RS01560	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KK0981_RS01560	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KK0981_RS01570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KK0981_RS01595	COG2723	6-phospho-beta-galactosidase activity
KK0981_RS01610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK0981_RS01610	COG3711	transcriptional antiterminator
KK0981_RS01625	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS01645	COG0386	Belongs to the glutathione peroxidase family
KK0981_RS01650	COG5492	domain, Protein
KK0981_RS01655	COG5492	domain, Protein
KK0981_RS01670	COG0800	Aldolase
KK0981_RS01685	COG1028	Short-chain dehydrogenase reductase Sdr
KK0981_RS01695	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
KK0981_RS01700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS01705	COG3715	PTS system
KK0981_RS01710	COG3716	PTS system mannose fructose sorbose family IID component
KK0981_RS01725	COG1609	Transcriptional regulator
KK0981_RS01755	COG4839	cell division protein FtsL
KK0981_RS01760	COG0768	penicillin binding
KK0981_RS01790	COG0366	Alpha amylase catalytic
KK0981_RS01795	COG4166	transmembrane transport
KK0981_RS01855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KK0981_RS01875	COG0366	Alpha amylase catalytic
KK0981_RS01880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK0981_RS01905	COG0116	Belongs to the methyltransferase superfamily
KK0981_RS01915	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KK0981_RS01920	COG0745	RESPONSE REGULATOR receiver
KK0981_RS01985	COG4585	Histidine kinase
KK0981_RS01990	COG2197	response regulator
KK0981_RS02020	COG0582	viral genome integration into host DNA
KK0981_RS02035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KK0981_RS02045	COG0681	Belongs to the peptidase S26 family
KK0981_RS02070	COG1115	amino acid carrier protein
KK0981_RS02095	COG0527	aspartate kinase activity
KK0981_RS02105	COG1024	Enoyl-CoA hydratase
KK0981_RS02110	COG1846	Transcriptional regulator
KK0981_RS02120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KK0981_RS02130	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KK0981_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
KK0981_RS02140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KK0981_RS02155	COG0439	Biotin carboxylase
KK0981_RS02160	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KK0981_RS02205	COG1063	alcohol dehydrogenase
KK0981_RS02210	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KK0981_RS02230	COG1442	glycosyl transferase family 8
KK0981_RS02235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KK0981_RS02245	COG1461	Dihydroxyacetone kinase
KK0981_RS02250	COG0028	Belongs to the TPP enzyme family
KK0981_RS02255	COG0440	acetolactate synthase activity
KK0981_RS02275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KK0981_RS02295	COG0765	amino acid transport
KK0981_RS02315	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KK0981_RS02325	COG1882	Formate acetyltransferase
KK0981_RS02395	COG1940	carbohydrate kinase activity
KK0981_RS02395	COG1846	Transcriptional regulator
KK0981_RS02400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS02410	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK0981_RS02415	COG2723	6-phospho-beta-galactosidase activity
KK0981_RS02425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KK0981_RS02430	COG0569	domain protein
KK0981_RS02450	COG1122	ATPase activity
KK0981_RS02465	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KK0981_RS02470	COG0671	phosphoesterase, PA-phosphatase related
KK0981_RS02480	COG1247	-acetyltransferase
KK0981_RS02490	COG0504	CTP synthase activity
KK0981_RS02495	COG1283	sodium-dependent phosphate transmembrane transporter activity
KK0981_RS02515	COG0789	Transcriptional regulator
KK0981_RS02520	COG0174	glutamine synthetase
KK0981_RS02545	COG4974	Belongs to the 'phage' integrase family
KK0981_RS02555	COG0732	type I restriction modification DNA specificity domain
KK0981_RS02600	COG0484	heat shock protein binding
KK0981_RS02615	COG0537	adenosine 5'-monophosphoramidase activity
KK0981_RS02620	COG1131	(ABC) transporter
KK0981_RS02645	COG3290	protein histidine kinase activity
KK0981_RS02655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KK0981_RS02745	COG1266	CAAX protease self-immunity
KK0981_RS02765	COG0195	Participates in both transcription termination and antitermination
KK0981_RS02770	COG2740	Nucleic-acid-binding protein implicated in transcription termination
KK0981_RS02825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK0981_RS02835	COG0525	valine-tRNA ligase activity
KK0981_RS02870	COG3711	transcriptional antiterminator
KK0981_RS02875	COG1263	PTS System
KK0981_RS02875	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS02875	COG2190	(PTS) system
KK0981_RS02890	COG0456	acetyltransferase
KK0981_RS02895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK0981_RS02895	COG0072	phenylalanine-tRNA ligase activity
KK0981_RS02910	COG3620	sequence-specific DNA binding
KK0981_RS02920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KK0981_RS02935	COG1045	serine acetyltransferase
KK0981_RS02950	COG0215	cysteine-tRNA ligase activity
KK0981_RS02955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KK0981_RS02970	COG0577	efflux transmembrane transporter activity
KK0981_RS02975	COG1136	(ABC) transporter
KK0981_RS02980	COG0577	efflux transmembrane transporter activity
KK0981_RS02985	COG0745	RESPONSE REGULATOR receiver
KK0981_RS02990	COG5002	protein histidine kinase activity
KK0981_RS02995	COG0191	fructose-bisphosphate aldolase activity
KK0981_RS03000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KK0981_RS03005	COG0765	amino acid transport
KK0981_RS03010	COG0765	amino acid transport
KK0981_RS03015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS03025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KK0981_RS03025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KK0981_RS03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS03080	COG1573	uracil-dna glycosylase
KK0981_RS03095	COG1114	Component of the transport system for branched-chain amino acids
KK0981_RS03100	COG1363	Peptidase, m42
KK0981_RS03155	COG4555	ABC transporter
KK0981_RS03185	COG1404	Belongs to the peptidase S8 family
KK0981_RS03200	COG3775	system Galactitol-specific IIC component
KK0981_RS03210	COG3250	beta-galactosidase activity
KK0981_RS03235	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KK0981_RS03260	COG0785	Cytochrome C biogenesis protein
KK0981_RS03265	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK0981_RS03270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KK0981_RS03270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KK0981_RS03280	COG4753	response regulator
KK0981_RS03280	COG2207	Transcriptional regulator
KK0981_RS03285	COG2972	Histidine kinase
KK0981_RS03290	COG4475	Protein of unknown function (DUF436)
KK0981_RS03295	COG3064	Membrane
KK0981_RS03300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KK0981_RS03315	COG1940	carbohydrate kinase activity
KK0981_RS03335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KK0981_RS03340	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
KK0981_RS03350	COG0300	oxidoreductase activity
KK0981_RS03365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KK0981_RS03375	COG1187	pseudouridine synthase activity
KK0981_RS03380	COG1217	gtp-binding protein TYPA
KK0981_RS03400	COG1136	(ABC) transporter
KK0981_RS03415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KK0981_RS03425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KK0981_RS03450	COG1131	(ABC) transporter
KK0981_RS03465	COG4215	(ABC) transporter
KK0981_RS03470	COG0765	amino acid transport
KK0981_RS03475	COG1304	FMN binding
KK0981_RS03485	COG1304	FMN binding
KK0981_RS03505	COG0352	thiamine-phosphate diphosphorylase activity
KK0981_RS03530	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KK0981_RS03545	COG0352	thiamine-phosphate diphosphorylase activity
KK0981_RS03570	COG2217	Heavy metal translocating P-type atpase
KK0981_RS03575	COG0028	Belongs to the TPP enzyme family
KK0981_RS03590	COG2723	6-phospho-beta-galactosidase activity
KK0981_RS03595	COG1482	cell wall glycoprotein biosynthetic process
KK0981_RS03615	COG2081	HI0933 family
KK0981_RS03620	COG1307	EDD domain protein, DegV family
KK0981_RS03630	COG2131	deaminase
KK0981_RS03635	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KK0981_RS03685	COG0617	tRNA 3'-terminal CCA addition
KK0981_RS03685	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KK0981_RS03685	COG0517	IMP dehydrogenase activity
KK0981_RS03695	COG2884	Cell division ATP-binding protein ftsE
KK0981_RS03700	COG2177	Part of the ABC transporter FtsEX involved in
KK0981_RS03705	COG2190	(PTS) system
KK0981_RS03705	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS03705	COG1263	PTS System
KK0981_RS03715	COG0513	Belongs to the DEAD box helicase family
KK0981_RS03730	COG0167	dihydroorotate dehydrogenase activity
KK0981_RS03740	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KK0981_RS03745	COG4470	Protein conserved in bacteria
KK0981_RS03760	COG0488	(ABC) transporter
KK0981_RS03790	COG1837	Belongs to the UPF0109 family
KK0981_RS03815	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KK0981_RS03815	COG1328	CTP reductase activity
KK0981_RS03825	COG4443	Transcriptional Coactivator p15 (PC4)
KK0981_RS03835	COG1268	BioY protein
KK0981_RS03840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK0981_RS03845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KK0981_RS03850	COG1136	(ABC) transporter
KK0981_RS03855	COG0577	efflux transmembrane transporter activity
KK0981_RS03860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK0981_RS03860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK0981_RS03880	COG4989	oxidoreductase activity
KK0981_RS03890	COG1028	Short-chain dehydrogenase reductase Sdr
KK0981_RS03910	COG0745	RESPONSE REGULATOR receiver
KK0981_RS03915	COG5002	protein histidine kinase activity
KK0981_RS03935	COG1199	ATP-dependent helicase activity
KK0981_RS03935	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KK0981_RS03940	COG0772	Belongs to the SEDS family
KK0981_RS03945	COG0693	protein deglycase activity
KK0981_RS03955	COG0187	DNA topoisomerase II activity
KK0981_RS03995	COG0494	nUDIX hydrolase
KK0981_RS04005	COG0542	response to heat
KK0981_RS04010	COG4703	Protein of unknown function (DUF1797)
KK0981_RS04015	COG0765	amino acid transport
KK0981_RS04020	COG1126	abc transporter atp-binding protein
KK0981_RS04025	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KK0981_RS04030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KK0981_RS04050	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KK0981_RS04110	COG2813	Specifically methylates the guanine in position
KK0981_RS04115	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KK0981_RS04125	COG0295	cytidine deaminase activity
KK0981_RS04130	COG1744	ABC transporter substrate-binding protein PnrA-like
KK0981_RS04135	COG3845	ABC transporter
KK0981_RS04140	COG4603	Belongs to the binding-protein-dependent transport system permease family
KK0981_RS04145	COG1079	Belongs to the binding-protein-dependent transport system permease family
KK0981_RS04160	COG0187	DNA topoisomerase II activity
KK0981_RS04165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KK0981_RS04170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KK0981_RS04210	COG0539	negative regulation of cytoplasmic translation
KK0981_RS04220	COG1956	GAF domain-containing protein
KK0981_RS04225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KK0981_RS04240	COG0719	Fe-S assembly protein
KK0981_RS04245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KK0981_RS04255	COG0719	Fe-S assembly protein
KK0981_RS04265	COG1686	Belongs to the peptidase S11 family
KK0981_RS04270	COG0628	permease
KK0981_RS04300	COG1349	DNA-binding transcription factor activity
KK0981_RS04305	COG1105	Belongs to the carbohydrate kinase PfkB family
KK0981_RS04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK0981_RS04310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK0981_RS04310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK0981_RS04315	COG0697	spore germination
KK0981_RS04315	COG1674	ftsk spoiiie
KK0981_RS04325	COG1104	cysteine desulfurase activity
KK0981_RS04385	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KK0981_RS04395	COG1438	arginine binding
KK0981_RS04415	COG0469	pyruvate kinase activity
KK0981_RS04420	COG0582	viral genome integration into host DNA
KK0981_RS04455	COG3689	TIGRFAM TIGR03943 family protein
KK0981_RS04460	COG0701	Predicted permease
KK0981_RS04470	COG2183	response to ionizing radiation
KK0981_RS04490	COG1136	(ABC) transporter
KK0981_RS04495	COG0577	efflux transmembrane transporter activity
KK0981_RS04510	COG1982	Orn Lys Arg decarboxylase major
KK0981_RS04520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KK0981_RS04540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KK0981_RS04545	COG0561	phosphatase activity
KK0981_RS04565	COG0583	DNA-binding transcription factor activity
KK0981_RS04570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KK0981_RS04575	COG0564	pseudouridine synthase activity
KK0981_RS04580	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KK0981_RS04595	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KK0981_RS04605	COG0470	DNA polymerase III
KK0981_RS04650	COG0528	UMP kinase activity
KK0981_RS04660	COG2996	Protein conserved in bacteria
KK0981_RS04670	COG1702	phosphate starvation-inducible protein PhoH
KK0981_RS04675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KK0981_RS04680	COG1596	polysaccharide export
KK0981_RS04680	COG1555	photosystem II stabilization
KK0981_RS04685	COG0658	competence protein
KK0981_RS04685	COG2333	competence protein COMEC
KK0981_RS04715	COG0543	2 iron, 2 sulfur cluster binding
KK0981_RS04720	COG0167	dihydroorotate dehydrogenase activity
KK0981_RS04725	COG5263	repeat protein
KK0981_RS04725	COG4193	domain, Protein
KK0981_RS04730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
KK0981_RS04740	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KK0981_RS04750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KK0981_RS04755	COG0237	dephospho-CoA kinase activity
KK0981_RS04760	COG2814	Major facilitator Superfamily
KK0981_RS04765	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KK0981_RS04775	COG0557	exoribonuclease II activity
KK0981_RS04785	COG0500	methyltransferase
KK0981_RS04785	COG3615	Tellurite resistance protein tehB
KK0981_RS04800	COG4122	O-methyltransferase activity
KK0981_RS04825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KK0981_RS04845	COG0494	nUDIX hydrolase
KK0981_RS04855	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KK0981_RS04865	COG2176	DNA-directed DNA polymerase activity
KK0981_RS04870	COG0584	glycerophosphoryl diester phosphodiesterase
KK0981_RS04890	COG0785	Cytochrome C biogenesis protein
KK0981_RS04895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK0981_RS04900	COG0531	amino acid
KK0981_RS04905	COG0803	Belongs to the bacterial solute-binding protein 9 family
KK0981_RS04905	COG3443	Belongs to the bacterial solute-binding protein 9 family
KK0981_RS04955	COG1970	mechanosensitive ion channel activity
KK0981_RS04965	COG4708	membrane
KK0981_RS04980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KK0981_RS04990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KK0981_RS04995	COG1942	4-Oxalocrotonate Tautomerase
KK0981_RS05000	COG1435	thymidine kinase activity
KK0981_RS05010	COG2890	protein-(glutamine-N5) methyltransferase activity
KK0981_RS05035	COG0741	lytic transglycosylase activity
KK0981_RS05045	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KK0981_RS05070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK0981_RS05075	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK0981_RS05120	COG1597	lipid kinase activity
KK0981_RS05130	COG0366	Alpha amylase catalytic
KK0981_RS05160	COG0772	Belongs to the SEDS family
KK0981_RS05165	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KK0981_RS05180	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KK0981_RS05185	COG0358	DNA primase activity
KK0981_RS05190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KK0981_RS05195	COG2151	metal-sulfur cluster biosynthetic enzyme
KK0981_RS05200	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS05205	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS05235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KK0981_RS05245	COG4109	DRTGG domain
KK0981_RS05250	COG0024	Methionine aminopeptidase
KK0981_RS05265	COG0210	DNA helicase
KK0981_RS05275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KK0981_RS05295	COG1104	cysteine desulfurase activity
KK0981_RS05300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KK0981_RS05310	COG2357	RelA SpoT domain protein
KK0981_RS05320	COG0564	pseudouridine synthase activity
KK0981_RS05325	COG0280	phosphate acetyltransferase
KK0981_RS05370	COG0196	riboflavin kinase activity
KK0981_RS05375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK0981_RS05380	COG1307	EDD domain protein, DegV family
KK0981_RS05390	COG0488	(ABC) transporter
KK0981_RS05410	COG1523	belongs to the glycosyl hydrolase 13 family
KK0981_RS05415	COG1012	belongs to the aldehyde dehydrogenase family
KK0981_RS05420	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KK0981_RS05430	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KK0981_RS05460	COG0582	viral genome integration into host DNA
KK0981_RS05485	COG1074	ATP-dependent DNA helicase activity
KK0981_RS05500	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KK0981_RS05500	COG3583	domain protein
KK0981_RS05525	COG0270	DNA (cytosine-5-)-methyltransferase activity
KK0981_RS05685	COG0488	(ABC) transporter
KK0981_RS05730	COG0741	lytic transglycosylase activity
KK0981_RS05730	COG0791	NLP P60 protein
KK0981_RS05760	COG2946	Replication initiation factor
KK0981_RS05770	COG1674	ftsk spoiiie
KK0981_RS05795	COG1396	sequence-specific DNA binding
KK0981_RS05830	COG1396	sequence-specific DNA binding
KK0981_RS05835	COG0542	response to heat
KK0981_RS05895	COG3843	relaxase mobilization nuclease domain protein
KK0981_RS05915	COG0515	serine threonine protein kinase
KK0981_RS05920	COG1122	ATPase activity
KK0981_RS05950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KK0981_RS05975	COG0095	Lipoate-protein ligase
KK0981_RS05980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK0981_RS05985	COG0508	dehydrogenase complex catalyzes the overall conversion of
KK0981_RS05990	COG0022	dehydrogenase e1 component
KK0981_RS05995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KK0981_RS06000	COG0534	Mate efflux family protein
KK0981_RS06010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KK0981_RS06015	COG1051	belongs to the nudix hydrolase family
KK0981_RS06030	COG1011	Hydrolase
KK0981_RS06035	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
KK0981_RS06055	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK0981_RS06060	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KK0981_RS06065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KK0981_RS06070	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KK0981_RS06105	COG3711	transcriptional antiterminator
KK0981_RS06110	COG3684	Belongs to the aldolase LacD family
KK0981_RS06160	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KK0981_RS06165	COG0497	DNA recombination
KK0981_RS06170	COG1438	arginine binding
KK0981_RS06175	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
KK0981_RS06190	COG1570	exodeoxyribonuclease VII activity
KK0981_RS06210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KK0981_RS06220	COG2873	o-acetylhomoserine
KK0981_RS06235	COG3764	Sortase (surface protein transpeptidase)
KK0981_RS06240	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KK0981_RS06250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KK0981_RS06265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KK0981_RS06270	COG5002	protein histidine kinase activity
KK0981_RS06275	COG0745	RESPONSE REGULATOR receiver
KK0981_RS06280	COG1194	a g-specific adenine glycosylase
KK0981_RS06300	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KK0981_RS06305	COG4684	Psort location CytoplasmicMembrane, score
KK0981_RS06315	COG1827	regulation of RNA biosynthetic process
KK0981_RS06345	COG0765	amino acid transport
KK0981_RS06350	COG1126	abc transporter atp-binding protein
KK0981_RS06355	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KK0981_RS06360	COG0552	protein localization to endoplasmic reticulum
KK0981_RS06365	COG0561	phosphatase activity
KK0981_RS06370	COG0561	phosphatase activity
KK0981_RS06375	COG1196	nuclear chromosome segregation
KK0981_RS06400	COG1401	restriction endodeoxyribonuclease activity
KK0981_RS06425	COG0473	3-isopropylmalate dehydrogenase activity
KK0981_RS06440	COG3142	Participates in the control of copper homeostasis
KK0981_RS06445	COG2832	Protein of unknown function (DUF454)
KK0981_RS06450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KK0981_RS06470	COG0758	DNA mediated transformation
KK0981_RS06475	COG4750	Nucleotidyl transferase
KK0981_RS06490	COG1063	alcohol dehydrogenase
KK0981_RS06505	COG3475	LICD family
KK0981_RS06510	COG3475	LICD family
KK0981_RS06520	COG0505	Belongs to the CarA family
KK0981_RS06535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KK0981_RS06550	COG0488	(ABC) transporter
KK0981_RS06560	COG1704	LemA family
KK0981_RS06575	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KK0981_RS06590	COG1078	dGTPase activity
KK0981_RS06610	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KK0981_RS06615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KK0981_RS06620	COG1605	Chorismate mutase
KK0981_RS06620	COG0077	Prephenate dehydratase
KK0981_RS06625	COG0716	FMN binding
KK0981_RS06630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KK0981_RS06650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KK0981_RS06695	COG0577	efflux transmembrane transporter activity
KK0981_RS06695	COG1136	(ABC) transporter
KK0981_RS06705	COG1770	oligopeptidase
KK0981_RS06760	COG0402	S-adenosylhomocysteine deaminase activity
KK0981_RS06770	COG1132	(ABC) transporter
KK0981_RS06775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KK0981_RS06775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KK0981_RS06815	COG1215	transferase activity, transferring glycosyl groups
KK0981_RS06825	COG3475	LICD family
KK0981_RS06835	COG0077	Prephenate dehydratase
KK0981_RS06840	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KK0981_RS06850	COG3679	Belongs to the UPF0342 family
KK0981_RS06855	COG0287	Prephenate dehydrogenase
KK0981_RS06880	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KK0981_RS06895	COG4555	ABC transporter
KK0981_RS06935	COG3842	ATPase activity
KK0981_RS06950	COG3527	Alpha-acetolactate decarboxylase
KK0981_RS06955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KK0981_RS06960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS06965	COG0704	Plays a role in the regulation of phosphate uptake
KK0981_RS06970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK0981_RS06975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK0981_RS06980	COG0581	inorganic phosphate transmembrane transporter activity
KK0981_RS06985	COG0573	inorganic phosphate transmembrane transporter activity
KK0981_RS06990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KK0981_RS06995	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KK0981_RS06995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KK0981_RS07000	COG0483	inositol monophosphate 1-phosphatase activity
KK0981_RS07010	COG1393	Belongs to the ArsC family
KK0981_RS07025	COG0647	UMP catabolic process
KK0981_RS07035	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KK0981_RS07055	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KK0981_RS07105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KK0981_RS07140	COG0826	peptidase U32
KK0981_RS07175	COG1129	ABC transporter
KK0981_RS07190	COG1132	(ABC) transporter
KK0981_RS07195	COG1132	(ABC) transporter
KK0981_RS07215	COG2188	Transcriptional regulator
KK0981_RS07220	COG0697	spore germination
KK0981_RS07225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KK0981_RS07240	COG0561	phosphatase activity
KK0981_RS07270	COG0492	ferredoxin-NADP+ reductase activity
KK0981_RS07280	COG1126	abc transporter atp-binding protein
KK0981_RS07290	COG1393	Belongs to the ArsC family
KK0981_RS07295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KK0981_RS07310	COG1272	protein, Hemolysin III
KK0981_RS07340	COG0431	NADPH-dependent FMN reductase
KK0981_RS07340	COG1053	succinate dehydrogenase
KK0981_RS07340	COG3976	FMN-binding domain protein
KK0981_RS07365	COG0656	L-ascorbic acid biosynthetic process
KK0981_RS07370	COG0726	polysaccharide deacetylase
KK0981_RS07400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KK0981_RS07440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KK0981_RS07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KK0981_RS07455	COG1126	abc transporter atp-binding protein
KK0981_RS07470	COG0628	permease
KK0981_RS07475	COG2706	6-phosphogluconolactonase activity
KK0981_RS07545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KK0981_RS07570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KK0981_RS07580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KK0981_RS07585	COG0626	cystathionine gamma-synthase activity
KK0981_RS07590	COG1132	(ABC) transporter
KK0981_RS07600	COG1132	(ABC) transporter
KK0981_RS07605	COG4166	transmembrane transport
KK0981_RS07610	COG2244	polysaccharide biosynthetic process
KK0981_RS07615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KK0981_RS07640	COG2827	Endonuclease containing a URI domain
KK0981_RS07645	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KK0981_RS07650	COG1098	S1 RNA binding domain
KK0981_RS07660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KK0981_RS07665	COG0629	single-stranded DNA binding
KK0981_RS07675	COG0017	Asparaginyl-tRNA synthetase
KK0981_RS07685	COG0436	Aminotransferase
KK0981_RS07730	COG0242	peptide deformylase activity
KK0981_RS07735	COG0625	glutathione transferase activity
KK0981_RS07745	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KK0981_RS07750	COG0488	(ABC) transporter
KK0981_RS07755	COG0617	tRNA 3'-terminal CCA addition
KK0981_RS07765	COG1307	EDD domain protein, DegV family
KK0981_RS07785	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KK0981_RS07790	COG0492	ferredoxin-NADP+ reductase activity
KK0981_RS07795	COG1481	regulation of sporulation
KK0981_RS07800	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KK0981_RS07810	COG0251	oxidation-reduction process
KK0981_RS07830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KK0981_RS07840	COG4193	domain, Protein
KK0981_RS07840	COG5263	repeat protein
KK0981_RS07850	COG3935	DnaD domain protein
KK0981_RS07865	COG2226	methyltransferase
KK0981_RS07875	COG3842	ATPase activity
KK0981_RS07885	COG1335	isochorismatase
KK0981_RS07900	COG0513	Belongs to the DEAD box helicase family
KK0981_RS07905	COG2223	nitrite transmembrane transporter activity
KK0981_RS07910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KK0981_RS07915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KK0981_RS07920	COG3442	glutamine amidotransferase
KK0981_RS07925	COG0006	proline dipeptidase activity
KK0981_RS07945	COG4720	Psort location CytoplasmicMembrane, score
KK0981_RS07950	COG0351	phosphomethylpyrimidine kinase
KK0981_RS07975	COG2824	Alkylphosphonate utilization operon protein PhnA
KK0981_RS08000	COG0463	Glycosyl transferase, family 2
KK0981_RS08005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KK0981_RS08015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KK0981_RS08020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KK0981_RS08025	COG2384	SAM-dependent methyltransferase
KK0981_RS08040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KK0981_RS08045	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KK0981_RS08050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK0981_RS08050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK0981_RS08050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KK0981_RS08055	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KK0981_RS08075	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KK0981_RS08080	COG0204	Acyl-transferase
KK0981_RS08095	COG2910	NAD(P)H-binding
KK0981_RS08125	COG5002	protein histidine kinase activity
KK0981_RS08130	COG0745	RESPONSE REGULATOR receiver
KK0981_RS08145	COG1959	2 iron, 2 sulfur cluster binding
KK0981_RS08195	COG3590	peptidase
KK0981_RS08210	COG0803	Belongs to the bacterial solute-binding protein 9 family
KK0981_RS08215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KK0981_RS08225	COG1136	(ABC) transporter
KK0981_RS08225	COG0577	efflux transmembrane transporter activity
KK0981_RS08270	COG3599	regulation of cell shape
KK0981_RS08290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KK0981_RS08310	COG1051	belongs to the nudix hydrolase family
KK0981_RS08315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KK0981_RS08330	COG0768	penicillin binding
KK0981_RS08345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KK0981_RS08365	COG2731	YhcH YjgK YiaL family protein
KK0981_RS08370	COG0395	ABC-type sugar transport system, permease component
KK0981_RS08375	COG1175	transmembrane transport
KK0981_RS08385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS08385	COG2190	(PTS) system
KK0981_RS08385	COG1263	PTS System
KK0981_RS08395	COG0673	inositol 2-dehydrogenase activity
KK0981_RS08400	COG4409	exo-alpha-(2->6)-sialidase activity
KK0981_RS08410	COG1175	transmembrane transport
KK0981_RS08415	COG1653	transport
KK0981_RS08440	COG3458	cephalosporin-C deacetylase activity
KK0981_RS08450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KK0981_RS08465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KK0981_RS08470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KK0981_RS08475	COG0653	protein targeting
KK0981_RS08485	COG1131	(ABC) transporter
KK0981_RS08530	COG1484	DNA-dependent DNA replication
KK0981_RS08545	COG1725	Transcriptional regulator
KK0981_RS08550	COG1131	(ABC) transporter
KK0981_RS08560	COG1668	transmembrane transport
KK0981_RS08565	COG4152	abc transporter atp-binding protein
KK0981_RS08585	COG1940	carbohydrate kinase activity
KK0981_RS08590	COG1263	PTS System
KK0981_RS08590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS08590	COG2190	(PTS) system
KK0981_RS08600	COG1621	beta-fructofuranosidase activity
KK0981_RS08605	COG1609	Transcriptional regulator
KK0981_RS08615	COG3425	synthase
KK0981_RS08640	COG2815	serine threonine protein kinase
KK0981_RS08640	COG0515	serine threonine protein kinase
KK0981_RS08645	COG0631	protein serine/threonine phosphatase activity
KK0981_RS08650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KK0981_RS08650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KK0981_RS08660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KK0981_RS08670	COG0194	GDP metabolic process
KK0981_RS08680	COG4115	mRNA cleavage
KK0981_RS08700	COG2226	methyltransferase
KK0981_RS08705	COG0799	negative regulation of ribosome biogenesis
KK0981_RS08715	COG1713	HD superfamily hydrolase involved in NAD metabolism
KK0981_RS08720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KK0981_RS08725	COG1534	Rna-binding protein
KK0981_RS08730	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KK0981_RS08745	COG0668	transmembrane transport
KK0981_RS08780	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS08785	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS08790	COG0653	protein targeting
KK0981_RS08810	COG0201	protein transport
KK0981_RS08815	COG1215	transferase activity, transferring glycosyl groups
KK0981_RS08820	COG1442	glycosyl transferase family 8
KK0981_RS08825	COG1442	glycosyl transferase family 8
KK0981_RS08830	COG1442	glycosyl transferase family 8
KK0981_RS08830	COG1216	Glycosyl transferase, family 2
KK0981_RS08835	COG1442	glycosyl transferase family 8
KK0981_RS08840	COG0438	transferase activity, transferring glycosyl groups
KK0981_RS08850	COG1442	glycosyl transferase family 8
KK0981_RS08850	COG1216	Glycosyl transferase, family 2
KK0981_RS08855	COG1442	glycosyl transferase family 8
KK0981_RS08860	COG1442	glycosyl transferase family 8
KK0981_RS08865	COG1216	Glycosyl transferase, family 2
KK0981_RS08865	COG1442	glycosyl transferase family 8
KK0981_RS08900	COG3118	belongs to the thioredoxin family
KK0981_RS08905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KK0981_RS08915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KK0981_RS08935	COG1131	(ABC) transporter
KK0981_RS08940	COG0640	Transcriptional regulator
KK0981_RS08945	COG1164	Oligoendopeptidase f
KK0981_RS08950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KK0981_RS09015	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KK0981_RS09025	COG1621	beta-fructofuranosidase activity
KK0981_RS09030	COG1653	transport
KK0981_RS09035	COG0395	ABC-type sugar transport system, permease component
KK0981_RS09050	COG3711	transcriptional antiterminator
KK0981_RS09075	COG3237	CsbD-like
KK0981_RS09085	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KK0981_RS09095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS09100	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK0981_RS09105	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS09115	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS09120	COG1846	Transcriptional regulator
KK0981_RS09120	COG1940	carbohydrate kinase activity
KK0981_RS09175	COG0512	Glutamine amidotransferase of anthranilate synthase
KK0981_RS09180	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KK0981_RS09200	COG1285	pathogenesis
KK0981_RS09205	COG1178	ABC-type Fe3 transport system permease component
KK0981_RS09235	COG5434	Belongs to the glycosyl hydrolase 28 family
KK0981_RS09245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KK0981_RS09250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KK0981_RS09260	COG1132	(ABC) transporter
KK0981_RS09265	COG1132	(ABC) transporter
KK0981_RS09290	COG0708	Exodeoxyribonuclease III
KK0981_RS09310	COG2233	PERMEase
KK0981_RS09335	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KK0981_RS09340	COG1609	Transcriptional regulator
KK0981_RS09345	COG1063	alcohol dehydrogenase
KK0981_RS09350	COG0789	Transcriptional regulator
KK0981_RS09355	COG1230	cation diffusion facilitator family transporter
KK0981_RS09365	COG3201	nicotinamide mononucleotide transporter
KK0981_RS09370	COG1174	glycine betaine transport
KK0981_RS09395	COG1363	Peptidase, m42
KK0981_RS09410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KK0981_RS09415	COG4605	iron ion homeostasis
KK0981_RS09420	COG4604	ABC transporter, ATP-binding protein
KK0981_RS09425	COG4607	ABC-type enterochelin transport system periplasmic component
KK0981_RS09435	COG1187	pseudouridine synthase activity
KK0981_RS09455	COG0517	IMP dehydrogenase activity
KK0981_RS09465	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KK0981_RS09485	COG0366	Alpha amylase catalytic
KK0981_RS09495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS09495	COG1263	PTS System
KK0981_RS09500	COG2188	Transcriptional regulator
KK0981_RS09510	COG4608	Belongs to the ABC transporter superfamily
KK0981_RS09515	COG0444	Belongs to the ABC transporter superfamily
KK0981_RS09520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KK0981_RS09525	COG0601	transmembrane transport
KK0981_RS09530	COG4166	transmembrane transport
KK0981_RS09545	COG0366	Alpha amylase catalytic
KK0981_RS09555	COG0395	ABC-type sugar transport system, permease component
KK0981_RS09560	COG1175	transmembrane transport
KK0981_RS09565	COG1653	transport
KK0981_RS09570	COG3345	alpha-galactosidase
KK0981_RS09580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KK0981_RS09580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KK0981_RS09700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KK0981_RS09705	COG3231	kanamycin kinase activity
KK0981_RS09745	COG4221	oxidoreductase activity
KK0981_RS09750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KK0981_RS09755	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KK0981_RS09850	COG3842	ATPase activity
KK0981_RS09855	COG1178	ABC-type Fe3 transport system permease component
KK0981_RS09860	COG1285	pathogenesis
KK0981_RS09920	COG5263	repeat protein
KK0981_RS09920	COG5632	N-Acetylmuramoyl-L-alanine amidase
KK0981_RS09945	COG1316	TRANSCRIPTIONal
KK0981_RS09955	COG0802	atpase or kinase
KK0981_RS09980	COG0577	efflux transmembrane transporter activity
KK0981_RS09980	COG1136	(ABC) transporter
KK0981_RS10020	COG1253	flavin adenine dinucleotide binding
KK0981_RS10035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KK0981_RS10045	COG3480	Lon protease (S16) C-terminal proteolytic domain
KK0981_RS10055	COG0742	ribosomal rna small subunit methyltransferase
KK0981_RS10075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KK0981_RS10080	COG1254	Belongs to the acylphosphatase family
KK0981_RS10090	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KK0981_RS10100	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KK0981_RS10120	COG1564	THIamine pyrophosphokinase
KK0981_RS10130	COG1162	GTPase activity
KK0981_RS10135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KK0981_RS10165	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KK0981_RS10170	COG0084	hydrolase, TatD family'
KK0981_RS10190	COG0436	Aminotransferase
KK0981_RS10200	COG0589	response to stress
KK0981_RS10205	COG0561	phosphatase activity
KK0981_RS10210	COG0252	asparaginase activity
KK0981_RS10220	COG1609	Transcriptional regulator
KK0981_RS10225	COG2197	response regulator
KK0981_RS10230	COG4585	Histidine kinase
KK0981_RS10240	COG1131	(ABC) transporter
KK0981_RS10340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KK0981_RS10345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK0981_RS10350	COG0564	pseudouridine synthase activity
KK0981_RS10360	COG0577	efflux transmembrane transporter activity
KK0981_RS10370	COG0157	Belongs to the NadC ModD family
KK0981_RS10385	COG1129	ABC transporter
KK0981_RS10390	COG2188	Transcriptional regulator
KK0981_RS10395	COG2723	6-phospho-beta-galactosidase activity
KK0981_RS10400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
KK0981_RS10410	COG1447	Phosphotransferase system cellobiose-specific component IIA
KK0981_RS10415	COG1454	alcohol dehydrogenase
KK0981_RS10415	COG1012	belongs to the aldehyde dehydrogenase family
KK0981_RS10425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KK0981_RS10435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KK0981_RS10455	COG3623	hexulose-6-phosphate isomerase
KK0981_RS10465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK0981_RS10475	COG3037	sugar-specific permease SgaT UlaA
KK0981_RS10485	COG1847	R3H domain protein
KK0981_RS10490	COG0706	membrane insertase activity
KK0981_RS10535	COG4537	Required for transformation and DNA binding
KK0981_RS10540	COG1459	type II secretion system
KK0981_RS10545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KK0981_RS10555	COG1063	alcohol dehydrogenase
KK0981_RS10580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KK0981_RS10585	COG3759	membrane
KK0981_RS10600	COG0131	Imidazoleglycerol-phosphate dehydratase
KK0981_RS10600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KK0981_RS10605	COG0534	Mate efflux family protein
KK0981_RS10725	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KK0981_RS10730	COG1132	(ABC) transporter
KK0981_RS10740	COG1132	(ABC) transporter
KK0981_RS10750	COG1438	arginine binding
KK0981_RS10770	COG0745	RESPONSE REGULATOR receiver
KK0981_RS10775	COG5002	protein histidine kinase activity
KK0981_RS10780	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KK0981_RS10785	COG0573	inorganic phosphate transmembrane transporter activity
KK0981_RS10795	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KK0981_RS10800	COG0704	Plays a role in the regulation of phosphate uptake
KK0981_RS10820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KK0981_RS10840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KK0981_RS10855	COG0697	spore germination
KK0981_RS10860	COG4499	WXG100 protein secretion system (Wss), protein YukC
KK0981_RS10860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KK0981_RS10870	COG2217	Heavy metal translocating P-type atpase
KK0981_RS10880	COG2226	methyltransferase
KK0981_RS10900	COG0058	SHG alpha-glucan phosphorylase activity
KK0981_RS10905	COG1640	4-alpha-glucanotransferase
KK0981_RS10910	COG2182	Extracellular solute-binding protein
KK0981_RS10915	COG1175	transmembrane transport
KK0981_RS10920	COG3833	ABC-type maltose transport systems, permease component
KK0981_RS10930	COG5521	maltodextrose utilization protein MalA
KK0981_RS10935	COG1609	Transcriptional regulator
KK0981_RS10945	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KK0981_RS10980	COG1476	TRANSCRIPTIONal
KK0981_RS11015	COG2151	metal-sulfur cluster biosynthetic enzyme
KK0981_RS11030	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KK0981_RS11035	COG3959	Transketolase, thiamine diphosphate binding domain
KK0981_RS11050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KK0981_RS11070	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KK0981_RS11085	COG0383	alpha-mannosidase activity
KK0981_RS11095	COG3537	Alpha-1,2-mannosidase
KK0981_RS11120	COG0549	Belongs to the carbamate kinase family
KK0981_RS11125	COG1288	antiporter activity
KK0981_RS11130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KK0981_RS11145	COG3525	Glycosyl hydrolase, family 20, catalytic domain
KK0981_RS11145	COG3583	domain protein
KK0981_RS11145	COG3064	Membrane
KK0981_RS11160	COG1454	alcohol dehydrogenase
KK0981_RS11165	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
KK0981_RS11180	COG3716	PTS system mannose fructose sorbose family IID component
KK0981_RS11190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KK0981_RS11210	COG1070	Carbohydrate kinase
KK0981_RS11225	COG3443	Belongs to the bacterial solute-binding protein 9 family
KK0981_RS11225	COG0803	Belongs to the bacterial solute-binding protein 9 family
KK0981_RS11230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KK0981_RS11235	COG1121	(ABC) transporter
KK0981_RS11245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KK0981_RS11255	COG1696	Membrane protein involved in D-alanine export
KK0981_RS11270	COG2211	Major facilitator Superfamily
KK0981_RS11275	COG3344	reverse transcriptase
KK0981_RS11295	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KK0981_RS11300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KK0981_RS11320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KK0981_RS11325	COG0366	Alpha amylase catalytic
KK0981_RS11330	COG1755	Isoprenylcysteine carboxyl methyltransferase
KK0981_RS11335	COG5002	protein histidine kinase activity
KK0981_RS11340	COG0745	RESPONSE REGULATOR receiver
KK0981_RS11345	COG0542	response to heat
KK0981_RS11350	COG4463	regulation of RNA biosynthetic process
KK0981_RS11355	COG1116	anion transmembrane transporter activity
KK0981_RS11365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KK0981_RS11385	COG0305	Participates in initiation and elongation during chromosome replication
KK0981_RS11405	COG1040	competence protein
KK0981_RS11410	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KK0981_RS11415	COG1739	Uncharacterized protein family UPF0029
KK0981_RS11460	COG3942	CHAP domain
KK0981_RS11470	COG1792	Involved in formation and maintenance of cell shape
KK0981_RS11475	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KK0981_RS11480	COG1122	ATPase activity
KK0981_RS11485	COG1122	ATPase activity
KK0981_RS11490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KK0981_RS11500	COG0612	Peptidase, M16
KK0981_RS11505	COG0612	Peptidase, M16
KK0981_RS11510	COG2501	S4 domain
KK0981_RS11520	COG0517	IMP dehydrogenase activity
KK0981_RS11520	COG0516	GMP reductase activity
KK0981_RS11525	COG0180	Tryptophanyl-tRNA synthetase
KK0981_RS11530	COG0488	(ABC) transporter
KK0981_RS11540	COG1511	domain protein
KK0981_RS11545	COG1511	domain protein
KK0981_RS11590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KK0981_RS11595	COG1475	DNA binding