locus-tag	class	description
DV130_RS00015	COG3842	ATPase activity
DV130_RS00020	COG2226	methyltransferase
DV130_RS00035	COG3935	DnaD domain protein
DV130_RS00045	COG5263	repeat protein
DV130_RS00045	COG4193	domain, Protein
DV130_RS00055	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DV130_RS00075	COG0251	oxidation-reduction process
DV130_RS00085	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DV130_RS00105	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DV130_RS00125	COG1307	EDD domain protein, DegV family
DV130_RS00135	COG0617	tRNA 3'-terminal CCA addition
DV130_RS00140	COG0488	(ABC) transporter
DV130_RS00145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DV130_RS00155	COG0625	glutathione transferase activity
DV130_RS00160	COG0242	peptide deformylase activity
DV130_RS00195	COG0436	Aminotransferase
DV130_RS00205	COG0017	Asparaginyl-tRNA synthetase
DV130_RS00215	COG0629	single-stranded DNA binding
DV130_RS00220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DV130_RS00230	COG1098	S1 RNA binding domain
DV130_RS00235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DV130_RS00240	COG2827	Endonuclease containing a URI domain
DV130_RS00265	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DV130_RS00270	COG2244	polysaccharide biosynthetic process
DV130_RS00275	COG4166	transmembrane transport
DV130_RS00285	COG1132	(ABC) transporter
DV130_RS00295	COG0626	cystathionine gamma-synthase activity
DV130_RS00300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DV130_RS00305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DV130_RS00330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DV130_RS00390	COG2706	6-phosphogluconolactonase activity
DV130_RS00395	COG0628	permease
DV130_RS00400	COG0457	Tetratricopeptide repeat
DV130_RS00410	COG1126	abc transporter atp-binding protein
DV130_RS00415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS00425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DV130_RS00470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DV130_RS00490	COG0513	Belongs to the DEAD box helicase family
DV130_RS00505	COG0726	polysaccharide deacetylase
DV130_RS00510	COG0656	L-ascorbic acid biosynthetic process
DV130_RS00535	COG3976	FMN-binding domain protein
DV130_RS00535	COG1053	succinate dehydrogenase
DV130_RS00535	COG0431	NADPH-dependent FMN reductase
DV130_RS00565	COG1272	protein, Hemolysin III
DV130_RS00580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DV130_RS00585	COG1393	Belongs to the ArsC family
DV130_RS00595	COG1126	abc transporter atp-binding protein
DV130_RS00605	COG0492	ferredoxin-NADP+ reductase activity
DV130_RS00640	COG0561	phosphatase activity
DV130_RS00655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DV130_RS00660	COG0697	spore germination
DV130_RS00665	COG2188	Transcriptional regulator
DV130_RS00695	COG0826	peptidase U32
DV130_RS00710	COG1131	(ABC) transporter
DV130_RS00730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DV130_RS00740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DV130_RS00770	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DV130_RS00790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DV130_RS00800	COG0647	UMP catabolic process
DV130_RS00810	COG1393	Belongs to the ArsC family
DV130_RS00820	COG0483	inositol monophosphate 1-phosphatase activity
DV130_RS00825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DV130_RS00825	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DV130_RS00830	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DV130_RS00835	COG0573	inorganic phosphate transmembrane transporter activity
DV130_RS00840	COG0581	inorganic phosphate transmembrane transporter activity
DV130_RS00845	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DV130_RS00850	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DV130_RS00855	COG0704	Plays a role in the regulation of phosphate uptake
DV130_RS00860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS00865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DV130_RS00870	COG3527	Alpha-acetolactate decarboxylase
DV130_RS00885	COG3842	ATPase activity
DV130_RS00925	COG1131	(ABC) transporter
DV130_RS00940	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DV130_RS00965	COG0287	Prephenate dehydrogenase
DV130_RS00975	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DV130_RS00980	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DV130_RS00985	COG0077	Prephenate dehydratase
DV130_RS00995	COG3475	LICD family
DV130_RS01005	COG1215	transferase activity, transferring glycosyl groups
DV130_RS01040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DV130_RS01040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DV130_RS01055	COG0402	S-adenosylhomocysteine deaminase activity
DV130_RS01105	COG0515	serine threonine protein kinase
DV130_RS01110	COG1770	oligopeptidase
DV130_RS01120	COG0577	efflux transmembrane transporter activity
DV130_RS01120	COG1136	(ABC) transporter
DV130_RS01150	COG0295	cytidine deaminase activity
DV130_RS01155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DV130_RS01185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DV130_RS01205	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DV130_RS01210	COG0716	FMN binding
DV130_RS01215	COG1605	Chorismate mutase
DV130_RS01215	COG0077	Prephenate dehydratase
DV130_RS01220	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DV130_RS01225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DV130_RS01245	COG1078	dGTPase activity
DV130_RS01275	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DV130_RS01290	COG1704	LemA family
DV130_RS01300	COG0488	(ABC) transporter
DV130_RS01315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DV130_RS01330	COG0505	Belongs to the CarA family
DV130_RS01340	COG3475	LICD family
DV130_RS01345	COG3475	LICD family
DV130_RS01360	COG1063	alcohol dehydrogenase
DV130_RS01375	COG4750	Nucleotidyl transferase
DV130_RS01380	COG0758	DNA mediated transformation
DV130_RS01390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DV130_RS01395	COG2832	Protein of unknown function (DUF454)
DV130_RS01400	COG3142	Participates in the control of copper homeostasis
DV130_RS01415	COG0473	3-isopropylmalate dehydrogenase activity
DV130_RS01425	COG0066	3-isopropylmalate dehydratase activity
DV130_RS01435	COG1401	restriction endodeoxyribonuclease activity
DV130_RS01460	COG1196	nuclear chromosome segregation
DV130_RS01465	COG0561	phosphatase activity
DV130_RS01470	COG0561	phosphatase activity
DV130_RS01475	COG0552	protein localization to endoplasmic reticulum
DV130_RS01480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DV130_RS01485	COG1126	abc transporter atp-binding protein
DV130_RS01490	COG0765	amino acid transport
DV130_RS01515	COG2816	NAD+ diphosphatase activity
DV130_RS01520	COG1827	regulation of RNA biosynthetic process
DV130_RS01530	COG4684	Psort location CytoplasmicMembrane, score
DV130_RS01535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DV130_RS01550	COG1194	a g-specific adenine glycosylase
DV130_RS01555	COG0745	RESPONSE REGULATOR receiver
DV130_RS01560	COG5002	protein histidine kinase activity
DV130_RS01565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DV130_RS01580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DV130_RS01590	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DV130_RS01595	COG3764	Sortase (surface protein transpeptidase)
DV130_RS01615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DV130_RS01650	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DV130_RS01655	COG1438	arginine binding
DV130_RS01660	COG0497	DNA recombination
DV130_RS01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DV130_RS01705	COG3684	Belongs to the aldolase LacD family
DV130_RS01710	COG3711	transcriptional antiterminator
DV130_RS01740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DV130_RS01745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DV130_RS01750	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DV130_RS01755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS01770	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
DV130_RS01775	COG1011	Hydrolase
DV130_RS01790	COG1051	belongs to the nudix hydrolase family
DV130_RS01795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DV130_RS01805	COG0534	Mate efflux family protein
DV130_RS01810	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DV130_RS01815	COG0022	dehydrogenase e1 component
DV130_RS01820	COG0508	dehydrogenase complex catalyzes the overall conversion of
DV130_RS01825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DV130_RS01830	COG0095	Lipoate-protein ligase
DV130_RS01835	COG0095	Lipoate-protein ligase
DV130_RS01850	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DV130_RS01855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DV130_RS01860	COG0582	viral genome integration into host DNA
DV130_RS01870	COG1396	sequence-specific DNA binding
DV130_RS01885	COG1122	ATPase activity
DV130_RS01910	COG3843	relaxase mobilization nuclease domain protein
DV130_RS01950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DV130_RS01960	COG0542	response to heat
DV130_RS01965	COG1396	sequence-specific DNA binding
DV130_RS02005	COG2197	response regulator
DV130_RS02020	COG1136	(ABC) transporter
DV130_RS02070	COG1136	(ABC) transporter
DV130_RS02130	COG0791	NLP P60 protein
DV130_RS02130	COG0741	lytic transglycosylase activity
DV130_RS02160	COG2946	Replication initiation factor
DV130_RS02170	COG1674	ftsk spoiiie
DV130_RS02255	COG0270	DNA (cytosine-5-)-methyltransferase activity
DV130_RS02280	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DV130_RS02280	COG3583	domain protein
DV130_RS02315	COG0582	viral genome integration into host DNA
DV130_RS02390	COG4974	Belongs to the 'phage' integrase family
DV130_RS02420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DV130_RS02430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DV130_RS02440	COG1012	belongs to the aldehyde dehydrogenase family
DV130_RS02445	COG1523	belongs to the glycosyl hydrolase 13 family
DV130_RS02465	COG0488	(ABC) transporter
DV130_RS02475	COG1307	EDD domain protein, DegV family
DV130_RS02480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DV130_RS02485	COG0196	riboflavin kinase activity
DV130_RS02535	COG0280	phosphate acetyltransferase
DV130_RS02540	COG0564	pseudouridine synthase activity
DV130_RS02550	COG2357	RelA SpoT domain protein
DV130_RS02560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DV130_RS02565	COG1104	cysteine desulfurase activity
DV130_RS02585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DV130_RS02595	COG0210	DNA helicase
DV130_RS02610	COG0024	Methionine aminopeptidase
DV130_RS02615	COG4109	DRTGG domain
DV130_RS02625	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DV130_RS02655	COG0438	transferase activity, transferring glycosyl groups
DV130_RS02660	COG0438	transferase activity, transferring glycosyl groups
DV130_RS02665	COG2151	metal-sulfur cluster biosynthetic enzyme
DV130_RS02670	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DV130_RS02675	COG0358	DNA primase activity
DV130_RS02680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DV130_RS02695	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DV130_RS02700	COG0772	Belongs to the SEDS family
DV130_RS02735	COG1597	lipid kinase activity
DV130_RS02785	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DV130_RS02790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DV130_RS02815	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DV130_RS02825	COG0741	lytic transglycosylase activity
DV130_RS02850	COG2890	protein-(glutamine-N5) methyltransferase activity
DV130_RS02855	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DV130_RS02860	COG1435	thymidine kinase activity
DV130_RS02865	COG1942	4-Oxalocrotonate Tautomerase
DV130_RS02880	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DV130_RS02890	COG4708	membrane
DV130_RS02900	COG1970	mechanosensitive ion channel activity
DV130_RS02945	COG0803	Belongs to the bacterial solute-binding protein 9 family
DV130_RS02945	COG3443	Belongs to the bacterial solute-binding protein 9 family
DV130_RS02950	COG0531	amino acid
DV130_RS02955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DV130_RS02960	COG0785	Cytochrome C biogenesis protein
DV130_RS02980	COG0584	glycerophosphoryl diester phosphodiesterase
DV130_RS02985	COG2176	DNA-directed DNA polymerase activity
DV130_RS02995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DV130_RS03005	COG0494	nUDIX hydrolase
DV130_RS03025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DV130_RS03030	COG0588	phosphoglycerate mutase activity
DV130_RS03055	COG4122	O-methyltransferase activity
DV130_RS03070	COG3615	Tellurite resistance protein tehB
DV130_RS03070	COG0500	methyltransferase
DV130_RS03080	COG0557	exoribonuclease II activity
DV130_RS03090	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DV130_RS03095	COG2814	Major facilitator Superfamily
DV130_RS03100	COG0237	dephospho-CoA kinase activity
DV130_RS03105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DV130_RS03115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DV130_RS03125	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DV130_RS03130	COG5263	repeat protein
DV130_RS03130	COG4193	domain, Protein
DV130_RS03135	COG0167	dihydroorotate dehydrogenase activity
DV130_RS03140	COG0543	2 iron, 2 sulfur cluster binding
DV130_RS03170	COG1131	(ABC) transporter
DV130_RS03180	COG0658	competence protein
DV130_RS03180	COG2333	competence protein COMEC
DV130_RS03185	COG1596	polysaccharide export
DV130_RS03185	COG1555	photosystem II stabilization
DV130_RS03190	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DV130_RS03195	COG0686	Belongs to the AlaDH PNT family
DV130_RS03200	COG0686	Belongs to the AlaDH PNT family
DV130_RS03205	COG0686	Belongs to the AlaDH PNT family
DV130_RS03225	COG1702	phosphate starvation-inducible protein PhoH
DV130_RS03235	COG2996	Protein conserved in bacteria
DV130_RS03245	COG0528	UMP kinase activity
DV130_RS03265	COG0470	DNA polymerase III
DV130_RS03275	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DV130_RS03290	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DV130_RS03295	COG0564	pseudouridine synthase activity
DV130_RS03300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DV130_RS03305	COG0583	DNA-binding transcription factor activity
DV130_RS03325	COG0561	phosphatase activity
DV130_RS03330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DV130_RS03350	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DV130_RS03360	COG1982	Orn Lys Arg decarboxylase major
DV130_RS03375	COG0577	efflux transmembrane transporter activity
DV130_RS03380	COG1136	(ABC) transporter
DV130_RS03400	COG2183	response to ionizing radiation
DV130_RS03415	COG0701	Predicted permease
DV130_RS03420	COG3689	TIGRFAM TIGR03943 family protein
DV130_RS03450	COG0469	pyruvate kinase activity
DV130_RS03470	COG1438	arginine binding
DV130_RS03480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
DV130_RS03535	COG1104	cysteine desulfurase activity
DV130_RS03545	COG1674	ftsk spoiiie
DV130_RS03545	COG0697	spore germination
DV130_RS03550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS03550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DV130_RS03550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DV130_RS03555	COG1105	Belongs to the carbohydrate kinase PfkB family
DV130_RS03560	COG1349	DNA-binding transcription factor activity
DV130_RS03575	COG0628	permease
DV130_RS03580	COG1686	Belongs to the peptidase S11 family
DV130_RS03585	COG0719	Fe-S assembly protein
DV130_RS03595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DV130_RS03600	COG0719	Fe-S assembly protein
DV130_RS03615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DV130_RS03620	COG1956	GAF domain-containing protein
DV130_RS03630	COG0539	negative regulation of cytoplasmic translation
DV130_RS03665	COG4166	transmembrane transport
DV130_RS03670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DV130_RS03675	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DV130_RS03680	COG0187	DNA topoisomerase II activity
DV130_RS03695	COG1079	Belongs to the binding-protein-dependent transport system permease family
DV130_RS03700	COG4603	Belongs to the binding-protein-dependent transport system permease family
DV130_RS03705	COG3845	ABC transporter
DV130_RS03710	COG1744	ABC transporter substrate-binding protein PnrA-like
DV130_RS03715	COG0295	cytidine deaminase activity
DV130_RS03725	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DV130_RS03730	COG2813	Specifically methylates the guanine in position
DV130_RS03780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DV130_RS03800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DV130_RS03805	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DV130_RS03810	COG1126	abc transporter atp-binding protein
DV130_RS03815	COG0765	amino acid transport
DV130_RS03820	COG4703	Protein of unknown function (DUF1797)
DV130_RS03825	COG0542	response to heat
DV130_RS03835	COG0494	nUDIX hydrolase
DV130_RS03875	COG0187	DNA topoisomerase II activity
DV130_RS03885	COG0693	protein deglycase activity
DV130_RS03890	COG0772	Belongs to the SEDS family
DV130_RS03915	COG5002	protein histidine kinase activity
DV130_RS03920	COG0745	RESPONSE REGULATOR receiver
DV130_RS03950	COG1028	Short-chain dehydrogenase reductase Sdr
DV130_RS03960	COG4989	oxidoreductase activity
DV130_RS03980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DV130_RS03980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DV130_RS03985	COG0577	efflux transmembrane transporter activity
DV130_RS03990	COG1136	(ABC) transporter
DV130_RS03995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DV130_RS04000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DV130_RS04005	COG1268	BioY protein
DV130_RS04015	COG4443	Transcriptional Coactivator p15 (PC4)
DV130_RS04025	COG1328	CTP reductase activity
DV130_RS04025	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DV130_RS04050	COG1837	Belongs to the UPF0109 family
DV130_RS04080	COG0488	(ABC) transporter
DV130_RS04095	COG4470	Protein conserved in bacteria
DV130_RS04100	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DV130_RS04110	COG0167	dihydroorotate dehydrogenase activity
DV130_RS04125	COG0513	Belongs to the DEAD box helicase family
DV130_RS04135	COG2190	(PTS) system
DV130_RS04135	COG1263	PTS System
DV130_RS04135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS04140	COG2177	Part of the ABC transporter FtsEX involved in
DV130_RS04145	COG2884	Cell division ATP-binding protein ftsE
DV130_RS04155	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DV130_RS04155	COG0617	tRNA 3'-terminal CCA addition
DV130_RS04155	COG0517	IMP dehydrogenase activity
DV130_RS04200	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DV130_RS04205	COG2131	deaminase
DV130_RS04215	COG1307	EDD domain protein, DegV family
DV130_RS04220	COG2081	HI0933 family
DV130_RS04230	COG0789	Transcriptional regulator
DV130_RS04235	COG0733	neurotransmitter:sodium symporter activity
DV130_RS04240	COG1482	cell wall glycoprotein biosynthetic process
DV130_RS04245	COG2723	6-phospho-beta-galactosidase activity
DV130_RS04260	COG0028	Belongs to the TPP enzyme family
DV130_RS04265	COG2217	Heavy metal translocating P-type atpase
DV130_RS04300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DV130_RS04310	COG4172	Belongs to the ABC transporter superfamily
DV130_RS04325	COG0352	thiamine-phosphate diphosphorylase activity
DV130_RS04345	COG1304	FMN binding
DV130_RS04355	COG1304	FMN binding
DV130_RS04365	COG4215	(ABC) transporter
DV130_RS04375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS04380	COG1131	(ABC) transporter
DV130_RS04405	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DV130_RS04415	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DV130_RS04430	COG1136	(ABC) transporter
DV130_RS04450	COG1217	gtp-binding protein TYPA
DV130_RS04455	COG1187	pseudouridine synthase activity
DV130_RS04465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DV130_RS04480	COG0300	oxidoreductase activity
DV130_RS04490	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DV130_RS04495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DV130_RS04515	COG1940	carbohydrate kinase activity
DV130_RS04530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DV130_RS04535	COG3064	Membrane
DV130_RS04545	COG2972	Histidine kinase
DV130_RS04550	COG4753	response regulator
DV130_RS04550	COG2207	Transcriptional regulator
DV130_RS04560	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DV130_RS04560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DV130_RS04565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DV130_RS04570	COG0785	Cytochrome C biogenesis protein
DV130_RS04590	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DV130_RS04610	COG3250	beta-galactosidase activity
DV130_RS04620	COG3775	system Galactitol-specific IIC component
DV130_RS04635	COG1404	Belongs to the peptidase S8 family
DV130_RS04665	COG4555	ABC transporter
DV130_RS04710	COG1363	Peptidase, m42
DV130_RS04715	COG1114	Component of the transport system for branched-chain amino acids
DV130_RS04730	COG1573	uracil-dna glycosylase
DV130_RS04745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS04785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DV130_RS04785	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DV130_RS04795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS04800	COG0765	amino acid transport
DV130_RS04805	COG0765	amino acid transport
DV130_RS04810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DV130_RS04815	COG0191	fructose-bisphosphate aldolase activity
DV130_RS04820	COG5002	protein histidine kinase activity
DV130_RS04825	COG0745	RESPONSE REGULATOR receiver
DV130_RS04830	COG0577	efflux transmembrane transporter activity
DV130_RS04835	COG1136	(ABC) transporter
DV130_RS04840	COG0577	efflux transmembrane transporter activity
DV130_RS04855	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DV130_RS04860	COG0215	cysteine-tRNA ligase activity
DV130_RS04875	COG1045	serine acetyltransferase
DV130_RS04900	COG3620	sequence-specific DNA binding
DV130_RS04915	COG0072	phenylalanine-tRNA ligase activity
DV130_RS04915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DV130_RS04920	COG0456	acetyltransferase
DV130_RS04935	COG1263	PTS System
DV130_RS04935	COG2190	(PTS) system
DV130_RS04935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS04940	COG3711	transcriptional antiterminator
DV130_RS04965	COG0525	valine-tRNA ligase activity
DV130_RS04975	COG0519	Catalyzes the synthesis of GMP from XMP
DV130_RS05035	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DV130_RS05040	COG0195	Participates in both transcription termination and antitermination
DV130_RS05060	COG1266	CAAX protease self-immunity
DV130_RS05155	COG2274	protein secretion by the type I secretion system
DV130_RS05185	COG3290	protein histidine kinase activity
DV130_RS05210	COG1131	(ABC) transporter
DV130_RS05215	COG0537	adenosine 5'-monophosphoramidase activity
DV130_RS05225	COG0484	heat shock protein binding
DV130_RS05275	COG4974	Belongs to the 'phage' integrase family
DV130_RS05285	COG0732	type I restriction modification DNA specificity domain
DV130_RS05305	COG0174	glutamine synthetase
DV130_RS05310	COG0789	Transcriptional regulator
DV130_RS05330	COG1283	sodium-dependent phosphate transmembrane transporter activity
DV130_RS05335	COG0504	CTP synthase activity
DV130_RS05345	COG1247	-acetyltransferase
DV130_RS05355	COG0671	phosphoesterase, PA-phosphatase related
DV130_RS05360	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DV130_RS05375	COG1122	ATPase activity
DV130_RS05395	COG0569	domain protein
DV130_RS05400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DV130_RS05410	COG2723	6-phospho-beta-galactosidase activity
DV130_RS05415	COG1447	Phosphotransferase system cellobiose-specific component IIA
DV130_RS05425	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS05430	COG1940	carbohydrate kinase activity
DV130_RS05430	COG1846	Transcriptional regulator
DV130_RS05500	COG1882	Formate acetyltransferase
DV130_RS05510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DV130_RS05530	COG0765	amino acid transport
DV130_RS05550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DV130_RS05570	COG0440	acetolactate synthase activity
DV130_RS05575	COG0028	Belongs to the TPP enzyme family
DV130_RS05580	COG1461	Dihydroxyacetone kinase
DV130_RS05590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DV130_RS05605	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DV130_RS05625	COG1063	alcohol dehydrogenase
DV130_RS05670	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DV130_RS05675	COG0439	Biotin carboxylase
DV130_RS05690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DV130_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
DV130_RS05700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DV130_RS05710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DV130_RS05720	COG1846	Transcriptional regulator
DV130_RS05725	COG1024	Enoyl-CoA hydratase
DV130_RS05735	COG0527	aspartate kinase activity
DV130_RS05745	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DV130_RS05760	COG1115	amino acid carrier protein
DV130_RS05785	COG0681	Belongs to the peptidase S26 family
DV130_RS05790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DV130_RS05800	COG0582	viral genome integration into host DNA
DV130_RS05830	COG2197	response regulator
DV130_RS05835	COG4585	Histidine kinase
DV130_RS05890	COG0745	RESPONSE REGULATOR receiver
DV130_RS05895	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DV130_RS05905	COG0116	Belongs to the methyltransferase superfamily
DV130_RS05930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DV130_RS05935	COG0366	Alpha amylase catalytic
DV130_RS05945	COG4166	transmembrane transport
DV130_RS05955	COG4372	Transposase
DV130_RS05965	COG1091	dTDP-4-dehydrorhamnose reductase activity
DV130_RS05970	COG1088	dTDP-glucose 4,6-dehydratase activity
DV130_RS05980	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DV130_RS05985	COG0647	UMP catabolic process
DV130_RS05990	COG1213	nucleotidyl transferase
DV130_RS05995	COG0371	Dehydrogenase
DV130_RS06015	COG1216	Glycosyl transferase, family 2
DV130_RS06015	COG1442	glycosyl transferase family 8
DV130_RS06035	COG0489	protein tyrosine kinase activity
DV130_RS06040	COG3944	biosynthesis protein
DV130_RS06045	COG4464	protein tyrosine phosphatase activity
DV130_RS06060	COG4166	transmembrane transport
DV130_RS06065	COG0366	Alpha amylase catalytic
DV130_RS06090	COG0768	penicillin binding
DV130_RS06095	COG4839	cell division protein FtsL
DV130_RS06120	COG1609	Transcriptional regulator
DV130_RS06135	COG3716	PTS system mannose fructose sorbose family IID component
DV130_RS06140	COG3715	PTS system
DV130_RS06145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS06150	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
DV130_RS06160	COG1028	Short-chain dehydrogenase reductase Sdr
DV130_RS06195	COG5492	domain, Protein
DV130_RS06205	COG0386	Belongs to the glutathione peroxidase family
DV130_RS06240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS06255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS06255	COG3711	transcriptional antiterminator
DV130_RS06270	COG2723	6-phospho-beta-galactosidase activity
DV130_RS06295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DV130_RS06305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DV130_RS06305	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DV130_RS06315	COG0285	dihydrofolate synthase activity
DV130_RS06320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DV130_RS06330	COG2252	PERMEase
DV130_RS06335	COG0561	phosphatase activity
DV130_RS06340	COG1064	alcohol dehydrogenase
DV130_RS06350	COG3715	PTS system
DV130_RS06355	COG3716	PTS system mannose fructose sorbose family IID component
DV130_RS06360	COG3579	cysteine-type endopeptidase activity
DV130_RS06370	COG1187	pseudouridine synthase activity
DV130_RS06380	COG2261	transglycosylase associated protein
DV130_RS06385	COG2309	aminopeptidase activity
DV130_RS06405	COG2176	DNA-directed DNA polymerase activity
DV130_RS06430	COG1523	belongs to the glycosyl hydrolase 13 family
DV130_RS06445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DV130_RS06450	COG2723	6-phospho-beta-galactosidase activity
DV130_RS06460	COG0750	zinc metalloprotease
DV130_RS06465	COG4589	Belongs to the CDS family
DV130_RS06470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DV130_RS06520	COG1882	Formate acetyltransferase
DV130_RS06525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS06530	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS06535	COG1447	Phosphotransferase system cellobiose-specific component IIA
DV130_RS06545	COG1349	DNA-binding transcription factor activity
DV130_RS06550	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DV130_RS06570	COG3842	ATPase activity
DV130_RS06575	COG3842	ATPase activity
DV130_RS06580	COG1178	ABC-type Fe3 transport system permease component
DV130_RS06605	COG3830	Belongs to the UPF0237 family
DV130_RS06615	COG0202	RNA polymerase activity
DV130_RS06620	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DV130_RS06630	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DV130_RS06635	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DV130_RS06645	COG0201	protein transport
DV130_RS06660	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DV130_RS06700	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DV130_RS06725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DV130_RS06790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DV130_RS06800	COG0285	dihydrofolate synthase activity
DV130_RS06825	COG1393	Belongs to the ArsC family
DV130_RS06835	COG0006	proline dipeptidase activity
DV130_RS06840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DV130_RS06920	COG0582	viral genome integration into host DNA
DV130_RS06945	COG2818	Glycosylase
DV130_RS06965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DV130_RS06965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DV130_RS07005	COG1780	Probably involved in ribonucleotide reductase function
DV130_RS07015	COG4753	response regulator
DV130_RS07015	COG2207	Transcriptional regulator
DV130_RS07020	COG2972	Histidine kinase
DV130_RS07040	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DV130_RS07045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DV130_RS07050	COG1464	Belongs to the NlpA lipoprotein family
DV130_RS07055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DV130_RS07085	COG1396	sequence-specific DNA binding
DV130_RS07140	COG0438	transferase activity, transferring glycosyl groups
DV130_RS07175	COG1214	PFAM Peptidase M22, glycoprotease
DV130_RS07210	COG0445	tRNA wobble uridine modification
DV130_RS07215	COG0494	nUDIX hydrolase
DV130_RS07330	COG1760	l-serine dehydratase
DV130_RS07335	COG1760	l-serine dehydratase
DV130_RS07340	COG0546	phosphoglycolate phosphatase activity
DV130_RS07365	COG1695	Transcriptional regulator
DV130_RS07395	COG1653	transport
DV130_RS07400	COG0395	ABC-type sugar transport system, permease component
DV130_RS07405	COG4209	transmembrane transport
DV130_RS07435	COG5002	protein histidine kinase activity
DV130_RS07455	COG1215	transferase activity, transferring glycosyl groups
DV130_RS07465	COG0569	domain protein
DV130_RS07470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DV130_RS07505	COG1937	Protein conserved in bacteria
DV130_RS07510	COG2514	catechol 2,3-dioxygenase activity
DV130_RS07520	COG2222	sugar isomerase
DV130_RS07530	COG3716	PTS system mannose fructose sorbose family IID component
DV130_RS07535	COG3715	PTS system
DV130_RS07540	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS07555	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DV130_RS07555	COG3583	domain protein
DV130_RS07555	COG3064	Membrane
DV130_RS07560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DV130_RS07575	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DV130_RS07590	COG0151	Belongs to the GarS family
DV130_RS07605	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DV130_RS07615	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DV130_RS07620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DV130_RS07635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DV130_RS07640	COG2274	protein secretion by the type I secretion system
DV130_RS07650	COG1388	LysM domain
DV130_RS07650	COG1134	teichoic acid transport
DV130_RS07680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DV130_RS07695	COG0436	Aminotransferase
DV130_RS07700	COG2855	membrane
DV130_RS07705	COG1832	CoA-binding protein
DV130_RS07710	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DV130_RS07710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DV130_RS07735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DV130_RS07750	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DV130_RS07760	COG0756	dUTP diphosphatase activity
DV130_RS07830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DV130_RS07835	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DV130_RS07855	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DV130_RS07860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DV130_RS07870	COG0012	GTP binding
DV130_RS07875	COG4974	Belongs to the 'phage' integrase family
DV130_RS07965	COG0592	DNA-directed DNA polymerase activity
DV130_RS07975	COG1475	DNA binding
DV130_RS07980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DV130_RS08035	COG0488	(ABC) transporter
DV130_RS08040	COG0180	Tryptophanyl-tRNA synthetase
DV130_RS08045	COG0517	IMP dehydrogenase activity
DV130_RS08045	COG0516	GMP reductase activity
DV130_RS08055	COG2501	S4 domain
DV130_RS08060	COG0612	Peptidase, M16
DV130_RS08065	COG0612	Peptidase, M16
DV130_RS08075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DV130_RS08080	COG1122	ATPase activity
DV130_RS08085	COG1122	ATPase activity
DV130_RS08090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DV130_RS08095	COG1792	Involved in formation and maintenance of cell shape
DV130_RS08105	COG3942	CHAP domain
DV130_RS08150	COG1739	Uncharacterized protein family UPF0029
DV130_RS08155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DV130_RS08160	COG1040	competence protein
DV130_RS08180	COG0305	Participates in initiation and elongation during chromosome replication
DV130_RS08200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DV130_RS08205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DV130_RS08210	COG1116	anion transmembrane transporter activity
DV130_RS08215	COG4463	regulation of RNA biosynthetic process
DV130_RS08220	COG0542	response to heat
DV130_RS08230	COG0745	RESPONSE REGULATOR receiver
DV130_RS08235	COG5002	protein histidine kinase activity
DV130_RS08240	COG1755	Isoprenylcysteine carboxyl methyltransferase
DV130_RS08245	COG0366	Alpha amylase catalytic
DV130_RS08250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DV130_RS08270	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DV130_RS08275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DV130_RS08310	COG2211	Major facilitator Superfamily
DV130_RS08325	COG1696	Membrane protein involved in D-alanine export
DV130_RS08335	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DV130_RS08340	COG1846	Transcriptional regulator
DV130_RS08345	COG1121	(ABC) transporter
DV130_RS08350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DV130_RS08355	COG0803	Belongs to the bacterial solute-binding protein 9 family
DV130_RS08355	COG3443	Belongs to the bacterial solute-binding protein 9 family
DV130_RS08370	COG1070	Carbohydrate kinase
DV130_RS08390	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS08400	COG3716	PTS system mannose fructose sorbose family IID component
DV130_RS08420	COG1454	alcohol dehydrogenase
DV130_RS08435	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DV130_RS08435	COG3583	domain protein
DV130_RS08435	COG3064	Membrane
DV130_RS08450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DV130_RS08455	COG1288	antiporter activity
DV130_RS08460	COG0549	Belongs to the carbamate kinase family
DV130_RS08485	COG3537	Alpha-1,2-mannosidase
DV130_RS08495	COG0383	alpha-mannosidase activity
DV130_RS08530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DV130_RS08550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS08565	COG3959	Transketolase, thiamine diphosphate binding domain
DV130_RS08570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DV130_RS08585	COG2151	metal-sulfur cluster biosynthetic enzyme
DV130_RS08605	COG0124	histidyl-tRNA synthetase
DV130_RS08620	COG1476	TRANSCRIPTIONal
DV130_RS08655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DV130_RS08675	COG1609	Transcriptional regulator
DV130_RS08680	COG5521	maltodextrose utilization protein MalA
DV130_RS08685	COG4974	Belongs to the 'phage' integrase family
DV130_RS08710	COG3620	sequence-specific DNA binding
DV130_RS08795	COG3833	ABC-type maltose transport systems, permease component
DV130_RS08800	COG1175	transmembrane transport
DV130_RS08805	COG2182	Extracellular solute-binding protein
DV130_RS08810	COG1640	4-alpha-glucanotransferase
DV130_RS08815	COG0058	SHG alpha-glucan phosphorylase activity
DV130_RS08835	COG2226	methyltransferase
DV130_RS08845	COG2217	Heavy metal translocating P-type atpase
DV130_RS08855	COG4499	WXG100 protein secretion system (Wss), protein YukC
DV130_RS08855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DV130_RS08860	COG0697	spore germination
DV130_RS08875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DV130_RS08890	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DV130_RS08910	COG0704	Plays a role in the regulation of phosphate uptake
DV130_RS08915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DV130_RS08925	COG0573	inorganic phosphate transmembrane transporter activity
DV130_RS08930	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DV130_RS08935	COG5002	protein histidine kinase activity
DV130_RS08940	COG0745	RESPONSE REGULATOR receiver
DV130_RS08965	COG1438	arginine binding
DV130_RS08975	COG1132	(ABC) transporter
DV130_RS08985	COG1132	(ABC) transporter
DV130_RS08990	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DV130_RS09115	COG0582	viral genome integration into host DNA
DV130_RS09150	COG1674	ftsk spoiiie
DV130_RS09180	COG0534	Mate efflux family protein
DV130_RS09185	COG0131	Imidazoleglycerol-phosphate dehydratase
DV130_RS09185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DV130_RS09200	COG3759	membrane
DV130_RS09205	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DV130_RS09230	COG1063	alcohol dehydrogenase
DV130_RS09240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DV130_RS09245	COG1459	type II secretion system
DV130_RS09250	COG4537	Required for transformation and DNA binding
DV130_RS09295	COG0706	membrane insertase activity
DV130_RS09300	COG1847	R3H domain protein
DV130_RS09310	COG3037	sugar-specific permease SgaT UlaA
DV130_RS09320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS09330	COG3623	hexulose-6-phosphate isomerase
DV130_RS09350	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DV130_RS09360	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DV130_RS09370	COG1454	alcohol dehydrogenase
DV130_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
DV130_RS09375	COG1447	Phosphotransferase system cellobiose-specific component IIA
DV130_RS09385	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS09390	COG2723	6-phospho-beta-galactosidase activity
DV130_RS09395	COG2188	Transcriptional regulator
DV130_RS09400	COG1129	ABC transporter
DV130_RS09415	COG0157	Belongs to the NadC ModD family
DV130_RS09425	COG0577	efflux transmembrane transporter activity
DV130_RS09435	COG0564	pseudouridine synthase activity
DV130_RS09440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DV130_RS09445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DV130_RS09545	COG1131	(ABC) transporter
DV130_RS09555	COG4585	Histidine kinase
DV130_RS09560	COG2197	response regulator
DV130_RS09565	COG1609	Transcriptional regulator
DV130_RS09575	COG0252	asparaginase activity
DV130_RS09580	COG0561	phosphatase activity
DV130_RS09585	COG0589	response to stress
DV130_RS09595	COG0436	Aminotransferase
DV130_RS09615	COG0084	hydrolase, TatD family'
DV130_RS09620	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DV130_RS09650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DV130_RS09655	COG1162	GTPase activity
DV130_RS09665	COG1564	THIamine pyrophosphokinase
DV130_RS09685	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DV130_RS09695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DV130_RS09705	COG1254	Belongs to the acylphosphatase family
DV130_RS09710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DV130_RS09730	COG0742	ribosomal rna small subunit methyltransferase
DV130_RS09740	COG3480	Lon protease (S16) C-terminal proteolytic domain
DV130_RS09750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DV130_RS09765	COG1253	flavin adenine dinucleotide binding
DV130_RS09795	COG1136	(ABC) transporter
DV130_RS09795	COG0577	efflux transmembrane transporter activity
DV130_RS09830	COG0802	atpase or kinase
DV130_RS09840	COG1316	TRANSCRIPTIONal
DV130_RS09865	COG5263	repeat protein
DV130_RS09865	COG5632	N-Acetylmuramoyl-L-alanine amidase
DV130_RS09925	COG1285	pathogenesis
DV130_RS09930	COG1178	ABC-type Fe3 transport system permease component
DV130_RS09935	COG3842	ATPase activity
DV130_RS10000	COG1132	(ABC) transporter
DV130_RS10035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DV130_RS10040	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DV130_RS10045	COG4221	oxidoreductase activity
DV130_RS10105	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DV130_RS10220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DV130_RS10220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DV130_RS10225	COG2207	Transcriptional regulator
DV130_RS10230	COG3345	alpha-galactosidase
DV130_RS10235	COG1653	transport
DV130_RS10240	COG1175	transmembrane transport
DV130_RS10245	COG0395	ABC-type sugar transport system, permease component
DV130_RS10250	COG0366	Alpha amylase catalytic
DV130_RS10265	COG4166	transmembrane transport
DV130_RS10270	COG0601	transmembrane transport
DV130_RS10275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DV130_RS10285	COG4608	Belongs to the ABC transporter superfamily
DV130_RS10305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DV130_RS10310	COG2188	Transcriptional regulator
DV130_RS10315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS10315	COG1263	PTS System
DV130_RS10325	COG0366	Alpha amylase catalytic
DV130_RS10340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DV130_RS10350	COG0517	IMP dehydrogenase activity
DV130_RS10370	COG1187	pseudouridine synthase activity
DV130_RS10380	COG4607	ABC-type enterochelin transport system periplasmic component
DV130_RS10385	COG4604	ABC transporter, ATP-binding protein
DV130_RS10390	COG4605	iron ion homeostasis
DV130_RS10395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DV130_RS10410	COG1363	Peptidase, m42
DV130_RS10435	COG1174	glycine betaine transport
DV130_RS10440	COG3201	nicotinamide mononucleotide transporter
DV130_RS10450	COG1230	cation diffusion facilitator family transporter
DV130_RS10455	COG0789	Transcriptional regulator
DV130_RS10460	COG1063	alcohol dehydrogenase
DV130_RS10465	COG1609	Transcriptional regulator
DV130_RS10470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DV130_RS10500	COG2233	PERMEase
DV130_RS10520	COG0708	Exodeoxyribonuclease III
DV130_RS10540	COG1132	(ABC) transporter
DV130_RS10545	COG1132	(ABC) transporter
DV130_RS10555	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DV130_RS10560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DV130_RS10570	COG5434	Belongs to the glycosyl hydrolase 28 family
DV130_RS10600	COG1178	ABC-type Fe3 transport system permease component
DV130_RS10605	COG1285	pathogenesis
DV130_RS10630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DV130_RS10635	COG0512	Glutamine amidotransferase of anthranilate synthase
DV130_RS10680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DV130_RS10690	COG1846	Transcriptional regulator
DV130_RS10690	COG1940	carbohydrate kinase activity
DV130_RS10695	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS10705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS10710	COG1447	Phosphotransferase system cellobiose-specific component IIA
DV130_RS10715	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DV130_RS10725	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DV130_RS10745	COG3237	CsbD-like
DV130_RS10765	COG2261	transglycosylase associated protein
DV130_RS10770	COG3711	transcriptional antiterminator
DV130_RS10780	COG4209	transmembrane transport
DV130_RS10785	COG0395	ABC-type sugar transport system, permease component
DV130_RS10790	COG1653	transport
DV130_RS10795	COG1621	beta-fructofuranosidase activity
DV130_RS10840	COG0582	viral genome integration into host DNA
DV130_RS10850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DV130_RS10895	COG1051	belongs to the nudix hydrolase family
DV130_RS10910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DV130_RS10915	COG1164	Oligoendopeptidase f
DV130_RS10920	COG0640	Transcriptional regulator
DV130_RS10925	COG1131	(ABC) transporter
DV130_RS10940	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DV130_RS10950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DV130_RS10955	COG3118	belongs to the thioredoxin family
DV130_RS10975	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DV130_RS10985	COG0668	transmembrane transport
DV130_RS11000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DV130_RS11005	COG1534	Rna-binding protein
DV130_RS11010	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DV130_RS11015	COG1713	HD superfamily hydrolase involved in NAD metabolism
DV130_RS11025	COG0799	negative regulation of ribosome biogenesis
DV130_RS11030	COG2226	methyltransferase
DV130_RS11050	COG0194	GDP metabolic process
DV130_RS11060	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DV130_RS11070	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DV130_RS11070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DV130_RS11075	COG0631	protein serine/threonine phosphatase activity
DV130_RS11080	COG0515	serine threonine protein kinase
DV130_RS11080	COG2815	serine threonine protein kinase
DV130_RS11105	COG3425	synthase
DV130_RS11115	COG1609	Transcriptional regulator
DV130_RS11120	COG1621	beta-fructofuranosidase activity
DV130_RS11135	COG1263	PTS System
DV130_RS11135	COG2190	(PTS) system
DV130_RS11135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS11140	COG1940	carbohydrate kinase activity
DV130_RS11160	COG4152	abc transporter atp-binding protein
DV130_RS11165	COG1668	transmembrane transport
DV130_RS11175	COG1131	(ABC) transporter
DV130_RS11180	COG1725	Transcriptional regulator
DV130_RS11195	COG1484	DNA-dependent DNA replication
DV130_RS11240	COG1131	(ABC) transporter
DV130_RS11255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DV130_RS11260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DV130_RS11275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DV130_RS11285	COG3458	cephalosporin-C deacetylase activity
DV130_RS11310	COG1653	transport
DV130_RS11315	COG1175	transmembrane transport
DV130_RS11325	COG4409	exo-alpha-(2->6)-sialidase activity
DV130_RS11330	COG0673	inositol 2-dehydrogenase activity
DV130_RS11340	COG1263	PTS System
DV130_RS11340	COG2190	(PTS) system
DV130_RS11340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DV130_RS11350	COG1175	transmembrane transport
DV130_RS11355	COG0395	ABC-type sugar transport system, permease component
DV130_RS11360	COG2731	YhcH YjgK YiaL family protein
DV130_RS11380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DV130_RS11395	COG0768	penicillin binding
DV130_RS11410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DV130_RS11430	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DV130_RS11450	COG3599	regulation of cell shape
DV130_RS11490	COG0577	efflux transmembrane transporter activity
DV130_RS11490	COG1136	(ABC) transporter
DV130_RS11500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DV130_RS11505	COG0803	Belongs to the bacterial solute-binding protein 9 family
DV130_RS11520	COG3590	peptidase
DV130_RS11570	COG1959	2 iron, 2 sulfur cluster binding
DV130_RS11585	COG0745	RESPONSE REGULATOR receiver
DV130_RS11590	COG5002	protein histidine kinase activity
DV130_RS11625	COG2910	NAD(P)H-binding
DV130_RS11640	COG0204	Acyl-transferase
DV130_RS11645	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DV130_RS11665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DV130_RS11670	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DV130_RS11670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DV130_RS11670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DV130_RS11675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DV130_RS11680	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DV130_RS11685	COG2801	Transposase and inactivated derivatives
DV130_RS11700	COG2384	SAM-dependent methyltransferase
DV130_RS11705	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DV130_RS11710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DV130_RS11720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DV130_RS11725	COG0463	Glycosyl transferase, family 2
DV130_RS11745	COG2824	Alkylphosphonate utilization operon protein PhnA
DV130_RS11770	COG0351	phosphomethylpyrimidine kinase
DV130_RS11775	COG4720	Psort location CytoplasmicMembrane, score
DV130_RS11790	COG0006	proline dipeptidase activity
DV130_RS11795	COG3442	glutamine amidotransferase
DV130_RS11800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DV130_RS11805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DV130_RS11810	COG2223	nitrite transmembrane transporter activity
DV130_RS11815	COG0513	Belongs to the DEAD box helicase family