locus-tag	class	description
EL277_RS00010	COG0592	DNA-directed DNA polymerase activity
EL277_RS00020	COG0012	GTP binding
EL277_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EL277_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EL277_RS00050	COG0037	tRNA processing
EL277_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EL277_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EL277_RS00135	COG0756	dUTP diphosphatase activity
EL277_RS00145	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EL277_RS00165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL277_RS00190	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL277_RS00190	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EL277_RS00195	COG1832	CoA-binding protein
EL277_RS00205	COG2855	membrane
EL277_RS00210	COG0436	Aminotransferase
EL277_RS00225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL277_RS00240	COG2274	protein secretion by the type I secretion system
EL277_RS00245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL277_RS00255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EL277_RS00260	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EL277_RS00265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EL277_RS00270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EL277_RS00280	COG0138	bifunctional purine biosynthesis protein purh
EL277_RS00285	COG0151	Belongs to the GarS family
EL277_RS00300	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EL277_RS00315	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EL277_RS00320	COG3064	Membrane
EL277_RS00320	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EL277_RS00320	COG3583	domain protein
EL277_RS00335	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS00340	COG3715	PTS system
EL277_RS00345	COG3716	PTS system mannose fructose sorbose family IID component
EL277_RS00355	COG2222	sugar isomerase
EL277_RS00375	COG3583	domain protein
EL277_RS00380	COG2514	catechol 2,3-dioxygenase activity
EL277_RS00385	COG0110	maltose O-acetyltransferase activity
EL277_RS00400	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL277_RS00405	COG0569	domain protein
EL277_RS00435	COG5002	protein histidine kinase activity
EL277_RS00465	COG4209	transmembrane transport
EL277_RS00470	COG0395	ABC-type sugar transport system, permease component
EL277_RS00475	COG1653	transport
EL277_RS00505	COG1695	Transcriptional regulator
EL277_RS00530	COG0546	phosphoglycolate phosphatase activity
EL277_RS00535	COG1760	l-serine dehydratase
EL277_RS00540	COG1760	l-serine dehydratase
EL277_RS00570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS00680	COG0494	nUDIX hydrolase
EL277_RS00685	COG0445	tRNA wobble uridine modification
EL277_RS00725	COG1214	PFAM Peptidase M22, glycoprotease
EL277_RS00735	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EL277_RS00765	COG0438	transferase activity, transferring glycosyl groups
EL277_RS00795	COG1396	sequence-specific DNA binding
EL277_RS00840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS00845	COG1464	Belongs to the NlpA lipoprotein family
EL277_RS00850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL277_RS00855	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL277_RS00875	COG2972	Histidine kinase
EL277_RS00880	COG2207	Transcriptional regulator
EL277_RS00880	COG4753	response regulator
EL277_RS00890	COG1780	Probably involved in ribonucleotide reductase function
EL277_RS00930	COG0019	diaminopimelate decarboxylase activity
EL277_RS00970	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL277_RS00970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EL277_RS00990	COG2818	Glycosylase
EL277_RS01015	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EL277_RS01020	COG0006	proline dipeptidase activity
EL277_RS01030	COG1393	Belongs to the ArsC family
EL277_RS01055	COG0285	dihydrofolate synthase activity
EL277_RS01065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EL277_RS01080	COG1328	CTP reductase activity
EL277_RS01130	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EL277_RS01155	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EL277_RS01185	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EL277_RS01195	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EL277_RS01210	COG0201	protein transport
EL277_RS01220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EL277_RS01225	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EL277_RS01235	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EL277_RS01240	COG0202	RNA polymerase activity
EL277_RS01245	COG0203	ribosomal protein L17
EL277_RS01250	COG3830	Belongs to the UPF0237 family
EL277_RS01255	COG2848	UPF0210 protein
EL277_RS01275	COG3842	ATPase activity
EL277_RS01285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EL277_RS01290	COG1349	DNA-binding transcription factor activity
EL277_RS01300	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL277_RS01305	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS01310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS01315	COG1882	Formate acetyltransferase
EL277_RS01330	COG0495	leucyl-tRNA aminoacylation
EL277_RS01355	COG2255	four-way junction helicase activity
EL277_RS01365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EL277_RS01370	COG4589	Belongs to the CDS family
EL277_RS01375	COG0750	zinc metalloprotease
EL277_RS01380	COG0442	prolyl-tRNA aminoacylation
EL277_RS01385	COG2723	6-phospho-beta-galactosidase activity
EL277_RS01390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EL277_RS01400	COG1523	belongs to the glycosyl hydrolase 13 family
EL277_RS01425	COG2176	DNA-directed DNA polymerase activity
EL277_RS01445	COG2309	aminopeptidase activity
EL277_RS01450	COG2261	transglycosylase associated protein
EL277_RS01460	COG1187	pseudouridine synthase activity
EL277_RS01470	COG3579	cysteine-type endopeptidase activity
EL277_RS01475	COG3716	PTS system mannose fructose sorbose family IID component
EL277_RS01480	COG3715	PTS system
EL277_RS01490	COG1064	alcohol dehydrogenase
EL277_RS01500	COG0561	phosphatase activity
EL277_RS01505	COG2252	PERMEase
EL277_RS01515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EL277_RS01520	COG0285	dihydrofolate synthase activity
EL277_RS01530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EL277_RS01530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EL277_RS01540	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EL277_RS01555	COG1373	ATPase (AAA superfamily
EL277_RS01575	COG2723	6-phospho-beta-galactosidase activity
EL277_RS01590	COG3711	transcriptional antiterminator
EL277_RS01590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS01605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS01625	COG0386	Belongs to the glutathione peroxidase family
EL277_RS01630	COG5492	domain, Protein
EL277_RS01665	COG1028	Short-chain dehydrogenase reductase Sdr
EL277_RS01675	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
EL277_RS01680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS01685	COG3715	PTS system
EL277_RS01690	COG3716	PTS system mannose fructose sorbose family IID component
EL277_RS01705	COG1609	Transcriptional regulator
EL277_RS01735	COG4839	cell division protein FtsL
EL277_RS01740	COG0768	penicillin binding
EL277_RS01770	COG0366	Alpha amylase catalytic
EL277_RS01775	COG4166	transmembrane transport
EL277_RS01790	COG4464	protein tyrosine phosphatase activity
EL277_RS01795	COG3944	biosynthesis protein
EL277_RS01800	COG0489	protein tyrosine kinase activity
EL277_RS01805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EL277_RS01820	COG0438	transferase activity, transferring glycosyl groups
EL277_RS01840	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL277_RS01855	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EL277_RS01890	COG4166	transmembrane transport
EL277_RS01900	COG0366	Alpha amylase catalytic
EL277_RS01905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL277_RS01930	COG0116	Belongs to the methyltransferase superfamily
EL277_RS01940	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EL277_RS01945	COG0745	RESPONSE REGULATOR receiver
EL277_RS02000	COG4585	Histidine kinase
EL277_RS02005	COG2197	response regulator
EL277_RS02045	COG2213	PTS system mannitol-specific
EL277_RS02050	COG3711	transcriptional antiterminator
EL277_RS02055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS02075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EL277_RS02080	COG0681	Belongs to the peptidase S26 family
EL277_RS02105	COG1115	amino acid carrier protein
EL277_RS02130	COG0527	aspartate kinase activity
EL277_RS02140	COG1024	Enoyl-CoA hydratase
EL277_RS02145	COG1846	Transcriptional regulator
EL277_RS02155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EL277_RS02165	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EL277_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
EL277_RS02175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EL277_RS02185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EL277_RS02190	COG0439	Biotin carboxylase
EL277_RS02195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EL277_RS02255	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EL277_RS02260	COG1442	glycosyl transferase family 8
EL277_RS02270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EL277_RS02280	COG1461	Dihydroxyacetone kinase
EL277_RS02285	COG0028	Belongs to the TPP enzyme family
EL277_RS02290	COG0440	acetolactate synthase activity
EL277_RS02310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EL277_RS02330	COG0765	amino acid transport
EL277_RS02350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EL277_RS02360	COG1882	Formate acetyltransferase
EL277_RS02430	COG1846	Transcriptional regulator
EL277_RS02430	COG1940	carbohydrate kinase activity
EL277_RS02435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS02445	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL277_RS02450	COG2723	6-phospho-beta-galactosidase activity
EL277_RS02455	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS02455	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS02460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EL277_RS02465	COG0569	domain protein
EL277_RS02480	COG1122	ATPase activity
EL277_RS02495	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EL277_RS02500	COG0671	phosphoesterase, PA-phosphatase related
EL277_RS02510	COG1247	-acetyltransferase
EL277_RS02520	COG0504	CTP synthase activity
EL277_RS02525	COG1283	sodium-dependent phosphate transmembrane transporter activity
EL277_RS02545	COG0789	Transcriptional regulator
EL277_RS02550	COG0174	glutamine synthetase
EL277_RS02575	COG4974	Belongs to the 'phage' integrase family
EL277_RS02585	COG0732	type I restriction modification DNA specificity domain
EL277_RS02630	COG0484	heat shock protein binding
EL277_RS02645	COG0537	adenosine 5'-monophosphoramidase activity
EL277_RS02650	COG1131	(ABC) transporter
EL277_RS02690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL277_RS02700	COG2274	protein secretion by the type I secretion system
EL277_RS02770	COG1266	CAAX protease self-immunity
EL277_RS02790	COG0195	Participates in both transcription termination and antitermination
EL277_RS02795	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EL277_RS02805	COG3064	Membrane
EL277_RS02805	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EL277_RS02810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EL277_RS02855	COG0519	Catalyzes the synthesis of GMP from XMP
EL277_RS02865	COG0525	valine-tRNA ligase activity
EL277_RS02915	COG3711	transcriptional antiterminator
EL277_RS02920	COG2190	(PTS) system
EL277_RS02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS02920	COG1263	PTS System
EL277_RS02935	COG0456	acetyltransferase
EL277_RS02940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL277_RS02940	COG0072	phenylalanine-tRNA ligase activity
EL277_RS02955	COG3620	sequence-specific DNA binding
EL277_RS02960	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EL277_RS02975	COG1185	polyribonucleotide nucleotidyltransferase activity
EL277_RS02980	COG1045	serine acetyltransferase
EL277_RS02995	COG0215	cysteine-tRNA ligase activity
EL277_RS03000	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EL277_RS03015	COG0577	efflux transmembrane transporter activity
EL277_RS03020	COG1136	(ABC) transporter
EL277_RS03025	COG0577	efflux transmembrane transporter activity
EL277_RS03030	COG0745	RESPONSE REGULATOR receiver
EL277_RS03035	COG5002	protein histidine kinase activity
EL277_RS03040	COG0191	fructose-bisphosphate aldolase activity
EL277_RS03045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EL277_RS03055	COG0765	amino acid transport
EL277_RS03060	COG0765	amino acid transport
EL277_RS03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS03075	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EL277_RS03075	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EL277_RS03115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS03130	COG1573	uracil-dna glycosylase
EL277_RS03145	COG1114	Component of the transport system for branched-chain amino acids
EL277_RS03150	COG1363	Peptidase, m42
EL277_RS03200	COG4555	ABC transporter
EL277_RS03225	COG1404	Belongs to the peptidase S8 family
EL277_RS03265	COG3775	system Galactitol-specific IIC component
EL277_RS03275	COG3250	beta-galactosidase activity
EL277_RS03305	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EL277_RS03325	COG0785	Cytochrome C biogenesis protein
EL277_RS03330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL277_RS03335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL277_RS03335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL277_RS03345	COG4753	response regulator
EL277_RS03345	COG2207	Transcriptional regulator
EL277_RS03350	COG2972	Histidine kinase
EL277_RS03355	COG4475	Protein of unknown function (DUF436)
EL277_RS03360	COG3064	Membrane
EL277_RS03365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL277_RS03380	COG1940	carbohydrate kinase activity
EL277_RS03400	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EL277_RS03405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EL277_RS03415	COG0300	oxidoreductase activity
EL277_RS03430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EL277_RS03440	COG1187	pseudouridine synthase activity
EL277_RS03445	COG1217	gtp-binding protein TYPA
EL277_RS03465	COG1136	(ABC) transporter
EL277_RS03470	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EL277_RS03475	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EL277_RS03480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EL277_RS03525	COG0284	orotidine-5'-phosphate decarboxylase activity
EL277_RS03530	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EL277_RS03555	COG1131	(ABC) transporter
EL277_RS03565	COG1126	abc transporter atp-binding protein
EL277_RS03570	COG0765	amino acid transport
EL277_RS03575	COG0765	amino acid transport
EL277_RS03580	COG1304	FMN binding
EL277_RS03585	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EL277_RS03590	COG1304	FMN binding
EL277_RS03605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EL277_RS03610	COG0352	thiamine-phosphate diphosphorylase activity
EL277_RS03625	COG4172	Belongs to the ABC transporter superfamily
EL277_RS03635	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EL277_RS03645	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EL277_RS03650	COG0352	thiamine-phosphate diphosphorylase activity
EL277_RS03670	COG2217	Heavy metal translocating P-type atpase
EL277_RS03675	COG0028	Belongs to the TPP enzyme family
EL277_RS03690	COG2723	6-phospho-beta-galactosidase activity
EL277_RS03695	COG1482	cell wall glycoprotein biosynthetic process
EL277_RS03705	COG0789	Transcriptional regulator
EL277_RS03715	COG2081	HI0933 family
EL277_RS03720	COG1307	EDD domain protein, DegV family
EL277_RS03730	COG2131	deaminase
EL277_RS03735	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EL277_RS03780	COG0617	tRNA 3'-terminal CCA addition
EL277_RS03780	COG0517	IMP dehydrogenase activity
EL277_RS03780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL277_RS03790	COG2884	Cell division ATP-binding protein ftsE
EL277_RS03795	COG2177	Part of the ABC transporter FtsEX involved in
EL277_RS03800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS03800	COG1263	PTS System
EL277_RS03800	COG2190	(PTS) system
EL277_RS03810	COG0513	Belongs to the DEAD box helicase family
EL277_RS03825	COG0167	dihydroorotate dehydrogenase activity
EL277_RS03835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EL277_RS03840	COG4470	Protein conserved in bacteria
EL277_RS03845	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EL277_RS03855	COG0488	(ABC) transporter
EL277_RS03880	COG1837	Belongs to the UPF0109 family
EL277_RS03895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EL277_RS03905	COG1328	CTP reductase activity
EL277_RS03905	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EL277_RS03915	COG4443	Transcriptional Coactivator p15 (PC4)
EL277_RS03925	COG1268	BioY protein
EL277_RS03930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL277_RS03935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EL277_RS03940	COG1136	(ABC) transporter
EL277_RS03945	COG0577	efflux transmembrane transporter activity
EL277_RS03950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL277_RS03950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL277_RS03970	COG4989	oxidoreductase activity
EL277_RS03980	COG1028	Short-chain dehydrogenase reductase Sdr
EL277_RS04005	COG0745	RESPONSE REGULATOR receiver
EL277_RS04010	COG5002	protein histidine kinase activity
EL277_RS04035	COG0772	Belongs to the SEDS family
EL277_RS04040	COG0693	protein deglycase activity
EL277_RS04050	COG0187	DNA topoisomerase II activity
EL277_RS04105	COG0542	response to heat
EL277_RS04110	COG4703	Protein of unknown function (DUF1797)
EL277_RS04120	COG0765	amino acid transport
EL277_RS04125	COG1126	abc transporter atp-binding protein
EL277_RS04130	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EL277_RS04140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EL277_RS04145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EL277_RS04160	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EL277_RS04200	COG0268	Binds directly to 16S ribosomal RNA
EL277_RS04205	COG1072	(Pantothenic acid kinase))
EL277_RS04215	COG2813	Specifically methylates the guanine in position
EL277_RS04220	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EL277_RS04240	COG0295	cytidine deaminase activity
EL277_RS04245	COG1744	ABC transporter substrate-binding protein PnrA-like
EL277_RS04250	COG3845	ABC transporter
EL277_RS04255	COG4603	Belongs to the binding-protein-dependent transport system permease family
EL277_RS04260	COG1079	Belongs to the binding-protein-dependent transport system permease family
EL277_RS04275	COG0187	DNA topoisomerase II activity
EL277_RS04280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL277_RS04285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EL277_RS04290	COG4166	transmembrane transport
EL277_RS04325	COG0539	negative regulation of cytoplasmic translation
EL277_RS04335	COG1956	GAF domain-containing protein
EL277_RS04340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EL277_RS04355	COG0719	Fe-S assembly protein
EL277_RS04360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EL277_RS04370	COG0719	Fe-S assembly protein
EL277_RS04375	COG1686	Belongs to the peptidase S11 family
EL277_RS04380	COG0628	permease
EL277_RS04395	COG1349	DNA-binding transcription factor activity
EL277_RS04400	COG1105	Belongs to the carbohydrate kinase PfkB family
EL277_RS04405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL277_RS04405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL277_RS04405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS04410	COG0697	spore germination
EL277_RS04410	COG1674	ftsk spoiiie
EL277_RS04420	COG1104	cysteine desulfurase activity
EL277_RS04480	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
EL277_RS04485	COG1438	arginine binding
EL277_RS04505	COG0469	pyruvate kinase activity
EL277_RS04555	COG3689	TIGRFAM TIGR03943 family protein
EL277_RS04560	COG0701	Predicted permease
EL277_RS04570	COG3955	Domain of unknown function (DUF1919)
EL277_RS04575	COG2183	response to ionizing radiation
EL277_RS04595	COG1136	(ABC) transporter
EL277_RS04600	COG0577	efflux transmembrane transporter activity
EL277_RS04620	COG1982	Orn Lys Arg decarboxylase major
EL277_RS04630	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EL277_RS04650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EL277_RS04655	COG0561	phosphatase activity
EL277_RS04675	COG0583	DNA-binding transcription factor activity
EL277_RS04680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EL277_RS04685	COG0564	pseudouridine synthase activity
EL277_RS04690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
EL277_RS04695	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EL277_RS04705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EL277_RS04715	COG0470	DNA polymerase III
EL277_RS04755	COG0528	UMP kinase activity
EL277_RS04765	COG2996	Protein conserved in bacteria
EL277_RS04775	COG1702	phosphate starvation-inducible protein PhoH
EL277_RS04800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EL277_RS04805	COG1596	polysaccharide export
EL277_RS04805	COG1555	photosystem II stabilization
EL277_RS04810	COG0658	competence protein
EL277_RS04810	COG2333	competence protein COMEC
EL277_RS04820	COG1131	(ABC) transporter
EL277_RS04850	COG0543	2 iron, 2 sulfur cluster binding
EL277_RS04855	COG0167	dihydroorotate dehydrogenase activity
EL277_RS04860	COG5263	repeat protein
EL277_RS04860	COG4193	domain, Protein
EL277_RS04865	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EL277_RS04875	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EL277_RS04885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EL277_RS04890	COG0237	dephospho-CoA kinase activity
EL277_RS04895	COG2814	Major facilitator Superfamily
EL277_RS04910	COG0557	exoribonuclease II activity
EL277_RS04920	COG0500	methyltransferase
EL277_RS04920	COG3615	Tellurite resistance protein tehB
EL277_RS04935	COG4122	O-methyltransferase activity
EL277_RS04965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EL277_RS04980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EL277_RS04985	COG0494	nUDIX hydrolase
EL277_RS04995	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EL277_RS05005	COG2176	DNA-directed DNA polymerase activity
EL277_RS05010	COG0584	glycerophosphoryl diester phosphodiesterase
EL277_RS05030	COG0785	Cytochrome C biogenesis protein
EL277_RS05035	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL277_RS05040	COG0531	amino acid
EL277_RS05045	COG3443	Belongs to the bacterial solute-binding protein 9 family
EL277_RS05045	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL277_RS05080	COG2195	Cleaves the N-terminal amino acid of tripeptides
EL277_RS05085	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EL277_RS05090	COG1970	mechanosensitive ion channel activity
EL277_RS05100	COG4708	membrane
EL277_RS05110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EL277_RS05125	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EL277_RS05130	COG1942	4-Oxalocrotonate Tautomerase
EL277_RS05135	COG1435	thymidine kinase activity
EL277_RS05145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EL277_RS05150	COG2890	protein-(glutamine-N5) methyltransferase activity
EL277_RS05165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EL277_RS05175	COG0741	lytic transglycosylase activity
EL277_RS05185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL277_RS05210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL277_RS05215	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL277_RS05265	COG1597	lipid kinase activity
EL277_RS05275	COG0366	Alpha amylase catalytic
EL277_RS05290	COG1396	sequence-specific DNA binding
EL277_RS05295	COG0542	response to heat
EL277_RS05320	COG3843	relaxase mobilization nuclease domain protein
EL277_RS05340	COG0515	serine threonine protein kinase
EL277_RS05345	COG1122	ATPase activity
EL277_RS05360	COG1396	sequence-specific DNA binding
EL277_RS05375	COG0772	Belongs to the SEDS family
EL277_RS05380	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EL277_RS05395	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EL277_RS05400	COG0358	DNA primase activity
EL277_RS05405	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EL277_RS05410	COG2151	metal-sulfur cluster biosynthetic enzyme
EL277_RS05415	COG0438	transferase activity, transferring glycosyl groups
EL277_RS05420	COG0438	transferase activity, transferring glycosyl groups
EL277_RS05445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL277_RS05455	COG4109	DRTGG domain
EL277_RS05460	COG0024	Methionine aminopeptidase
EL277_RS05475	COG0210	DNA helicase
EL277_RS05485	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EL277_RS05505	COG1104	cysteine desulfurase activity
EL277_RS05510	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EL277_RS05520	COG2357	RelA SpoT domain protein
EL277_RS05530	COG0564	pseudouridine synthase activity
EL277_RS05535	COG0280	phosphate acetyltransferase
EL277_RS05575	COG0196	riboflavin kinase activity
EL277_RS05580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL277_RS05585	COG1307	EDD domain protein, DegV family
EL277_RS05595	COG0488	(ABC) transporter
EL277_RS05615	COG1523	belongs to the glycosyl hydrolase 13 family
EL277_RS05620	COG1012	belongs to the aldehyde dehydrogenase family
EL277_RS05630	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EL277_RS05640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EL277_RS05670	COG0582	viral genome integration into host DNA
EL277_RS05690	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EL277_RS05710	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EL277_RS05710	COG3583	domain protein
EL277_RS05720	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EL277_RS05725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EL277_RS05735	COG4974	Belongs to the 'phage' integrase family
EL277_RS05740	COG0095	Lipoate-protein ligase
EL277_RS05745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL277_RS05750	COG0508	dehydrogenase complex catalyzes the overall conversion of
EL277_RS05755	COG0022	dehydrogenase e1 component
EL277_RS05760	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EL277_RS05765	COG0534	Mate efflux family protein
EL277_RS05775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EL277_RS05780	COG1051	belongs to the nudix hydrolase family
EL277_RS05795	COG1011	Hydrolase
EL277_RS05800	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
EL277_RS05820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS05825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EL277_RS05830	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL277_RS05835	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EL277_RS05855	COG2723	6-phospho-beta-galactosidase activity
EL277_RS05870	COG3711	transcriptional antiterminator
EL277_RS05875	COG3684	Belongs to the aldolase LacD family
EL277_RS05925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EL277_RS05930	COG0497	DNA recombination
EL277_RS05935	COG1438	arginine binding
EL277_RS05940	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EL277_RS05975	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EL277_RS05995	COG3764	Sortase (surface protein transpeptidase)
EL277_RS06000	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EL277_RS06030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EL277_RS06035	COG5002	protein histidine kinase activity
EL277_RS06040	COG0745	RESPONSE REGULATOR receiver
EL277_RS06045	COG1194	a g-specific adenine glycosylase
EL277_RS06050	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EL277_RS06060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EL277_RS06065	COG4684	Psort location CytoplasmicMembrane, score
EL277_RS06075	COG1827	regulation of RNA biosynthetic process
EL277_RS06080	COG2816	NAD+ diphosphatase activity
EL277_RS06105	COG0765	amino acid transport
EL277_RS06110	COG1126	abc transporter atp-binding protein
EL277_RS06115	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EL277_RS06120	COG0552	protein localization to endoplasmic reticulum
EL277_RS06125	COG0561	phosphatase activity
EL277_RS06130	COG0561	phosphatase activity
EL277_RS06135	COG1196	nuclear chromosome segregation
EL277_RS06160	COG1401	restriction endodeoxyribonuclease activity
EL277_RS06170	COG0066	3-isopropylmalate dehydratase activity
EL277_RS06180	COG0473	3-isopropylmalate dehydrogenase activity
EL277_RS06195	COG3142	Participates in the control of copper homeostasis
EL277_RS06200	COG2832	Protein of unknown function (DUF454)
EL277_RS06205	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EL277_RS06225	COG0758	DNA mediated transformation
EL277_RS06230	COG4750	Nucleotidyl transferase
EL277_RS06245	COG1063	alcohol dehydrogenase
EL277_RS06250	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EL277_RS06260	COG3475	LICD family
EL277_RS06265	COG3475	LICD family
EL277_RS06275	COG0505	Belongs to the CarA family
EL277_RS06290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EL277_RS06305	COG0488	(ABC) transporter
EL277_RS06315	COG1704	LemA family
EL277_RS06330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EL277_RS06345	COG1078	dGTPase activity
EL277_RS06395	COG2946	Replication initiation factor
EL277_RS06405	COG0582	viral genome integration into host DNA
EL277_RS06420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL277_RS06425	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EL277_RS06430	COG1605	Chorismate mutase
EL277_RS06430	COG0077	Prephenate dehydratase
EL277_RS06435	COG0716	FMN binding
EL277_RS06440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EL277_RS06460	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EL277_RS06555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EL277_RS06560	COG1269	ATP hydrolysis coupled proton transport
EL277_RS06575	COG0673	inositol 2-dehydrogenase activity
EL277_RS06580	COG4409	exo-alpha-(2->6)-sialidase activity
EL277_RS06590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EL277_RS06595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL277_RS06600	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
EL277_RS06605	COG1737	Transcriptional regulator
EL277_RS06655	COG1136	(ABC) transporter
EL277_RS06655	COG0577	efflux transmembrane transporter activity
EL277_RS06665	COG0515	serine threonine protein kinase
EL277_RS06700	COG0402	S-adenosylhomocysteine deaminase activity
EL277_RS06710	COG1132	(ABC) transporter
EL277_RS06715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL277_RS06715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EL277_RS06735	COG4862	establishment of competence for transformation
EL277_RS06750	COG1215	transferase activity, transferring glycosyl groups
EL277_RS06760	COG3475	LICD family
EL277_RS06770	COG0077	Prephenate dehydratase
EL277_RS06775	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EL277_RS06780	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EL277_RS06790	COG0287	Prephenate dehydrogenase
EL277_RS06815	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EL277_RS06840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EL277_RS06870	COG3842	ATPase activity
EL277_RS06885	COG3527	Alpha-acetolactate decarboxylase
EL277_RS06890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EL277_RS06895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS06900	COG0704	Plays a role in the regulation of phosphate uptake
EL277_RS06905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL277_RS06910	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL277_RS06915	COG0581	inorganic phosphate transmembrane transporter activity
EL277_RS06920	COG0573	inorganic phosphate transmembrane transporter activity
EL277_RS06925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL277_RS06930	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EL277_RS06930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL277_RS06935	COG0483	inositol monophosphate 1-phosphatase activity
EL277_RS06945	COG1393	Belongs to the ArsC family
EL277_RS06955	COG0647	UMP catabolic process
EL277_RS06965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EL277_RS06985	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EL277_RS07035	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EL277_RS07055	COG1131	(ABC) transporter
EL277_RS07070	COG0826	peptidase U32
EL277_RS07100	COG1132	(ABC) transporter
EL277_RS07120	COG1129	ABC transporter
EL277_RS07180	COG2188	Transcriptional regulator
EL277_RS07185	COG0697	spore germination
EL277_RS07190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EL277_RS07205	COG0561	phosphatase activity
EL277_RS07240	COG0492	ferredoxin-NADP+ reductase activity
EL277_RS07250	COG1126	abc transporter atp-binding protein
EL277_RS07260	COG1393	Belongs to the ArsC family
EL277_RS07265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EL277_RS07280	COG1272	protein, Hemolysin III
EL277_RS07310	COG0431	NADPH-dependent FMN reductase
EL277_RS07310	COG1053	succinate dehydrogenase
EL277_RS07310	COG3976	FMN-binding domain protein
EL277_RS07330	COG0752	glycyl-tRNA synthetase alpha subunit
EL277_RS07340	COG0656	L-ascorbic acid biosynthetic process
EL277_RS07345	COG0726	polysaccharide deacetylase
EL277_RS07395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL277_RS07430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EL277_RS07445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EL277_RS07450	COG1126	abc transporter atp-binding protein
EL277_RS07475	COG0628	permease
EL277_RS07480	COG2706	6-phosphogluconolactonase activity
EL277_RS07495	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EL277_RS07540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EL277_RS07545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EL277_RS07570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EL277_RS07575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EL277_RS07580	COG0626	cystathionine gamma-synthase activity
EL277_RS07585	COG1132	(ABC) transporter
EL277_RS07590	COG1132	(ABC) transporter
EL277_RS07595	COG4166	transmembrane transport
EL277_RS07600	COG2244	polysaccharide biosynthetic process
EL277_RS07605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EL277_RS07630	COG2827	Endonuclease containing a URI domain
EL277_RS07635	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EL277_RS07640	COG1098	S1 RNA binding domain
EL277_RS07650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EL277_RS07655	COG0629	single-stranded DNA binding
EL277_RS07665	COG0017	Asparaginyl-tRNA synthetase
EL277_RS07675	COG0436	Aminotransferase
EL277_RS07695	COG3022	response to hydroperoxide
EL277_RS07710	COG0242	peptide deformylase activity
EL277_RS07715	COG0625	glutathione transferase activity
EL277_RS07725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EL277_RS07730	COG0488	(ABC) transporter
EL277_RS07735	COG0617	tRNA 3'-terminal CCA addition
EL277_RS07745	COG1307	EDD domain protein, DegV family
EL277_RS07765	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EL277_RS07780	COG1481	regulation of sporulation
EL277_RS07785	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EL277_RS07795	COG0251	oxidation-reduction process
EL277_RS07815	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EL277_RS07825	COG5263	repeat protein
EL277_RS07825	COG4193	domain, Protein
EL277_RS07835	COG3935	DnaD domain protein
EL277_RS07850	COG2226	methyltransferase
EL277_RS07855	COG3842	ATPase activity
EL277_RS07870	COG1335	isochorismatase
EL277_RS07875	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EL277_RS07885	COG0513	Belongs to the DEAD box helicase family
EL277_RS07890	COG2223	nitrite transmembrane transporter activity
EL277_RS07895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EL277_RS07900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL277_RS07905	COG3442	glutamine amidotransferase
EL277_RS07910	COG0006	proline dipeptidase activity
EL277_RS07935	COG4720	Psort location CytoplasmicMembrane, score
EL277_RS07940	COG0351	phosphomethylpyrimidine kinase
EL277_RS07965	COG2824	Alkylphosphonate utilization operon protein PhnA
EL277_RS07970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EL277_RS07985	COG0463	Glycosyl transferase, family 2
EL277_RS07990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EL277_RS08000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EL277_RS08005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EL277_RS08010	COG2384	SAM-dependent methyltransferase
EL277_RS08025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL277_RS08030	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EL277_RS08035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS08035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL277_RS08035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL277_RS08040	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EL277_RS08065	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EL277_RS08070	COG0204	Acyl-transferase
EL277_RS08085	COG2910	NAD(P)H-binding
EL277_RS08110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EL277_RS08115	COG5002	protein histidine kinase activity
EL277_RS08120	COG0745	RESPONSE REGULATOR receiver
EL277_RS08135	COG1959	2 iron, 2 sulfur cluster binding
EL277_RS08195	COG3590	peptidase
EL277_RS08210	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL277_RS08215	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EL277_RS08225	COG0577	efflux transmembrane transporter activity
EL277_RS08225	COG1136	(ABC) transporter
EL277_RS08270	COG3599	regulation of cell shape
EL277_RS08290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EL277_RS08310	COG1051	belongs to the nudix hydrolase family
EL277_RS08315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EL277_RS08320	COG1181	Belongs to the D-alanine--D-alanine ligase family
EL277_RS08330	COG0768	penicillin binding
EL277_RS08345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EL277_RS08365	COG2731	YhcH YjgK YiaL family protein
EL277_RS08375	COG0395	ABC-type sugar transport system, permease component
EL277_RS08380	COG1175	transmembrane transport
EL277_RS08390	COG2190	(PTS) system
EL277_RS08390	COG1263	PTS System
EL277_RS08390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS08400	COG0673	inositol 2-dehydrogenase activity
EL277_RS08405	COG4409	exo-alpha-(2->6)-sialidase activity
EL277_RS08415	COG1175	transmembrane transport
EL277_RS08420	COG1653	transport
EL277_RS08445	COG3458	cephalosporin-C deacetylase activity
EL277_RS08460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EL277_RS08475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EL277_RS08480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EL277_RS08485	COG0653	protein targeting
EL277_RS08495	COG1131	(ABC) transporter
EL277_RS08525	COG0778	Nitroreductase
EL277_RS08530	COG1484	DNA-dependent DNA replication
EL277_RS08545	COG1725	Transcriptional regulator
EL277_RS08550	COG1131	(ABC) transporter
EL277_RS08560	COG1668	transmembrane transport
EL277_RS08565	COG4152	abc transporter atp-binding protein
EL277_RS08585	COG1940	carbohydrate kinase activity
EL277_RS08590	COG1263	PTS System
EL277_RS08590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS08590	COG2190	(PTS) system
EL277_RS08600	COG1621	beta-fructofuranosidase activity
EL277_RS08605	COG1609	Transcriptional regulator
EL277_RS08615	COG3425	synthase
EL277_RS08640	COG0515	serine threonine protein kinase
EL277_RS08640	COG2815	serine threonine protein kinase
EL277_RS08645	COG0631	protein serine/threonine phosphatase activity
EL277_RS08650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EL277_RS08650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EL277_RS08660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EL277_RS08670	COG0194	GDP metabolic process
EL277_RS08680	COG4115	mRNA cleavage
EL277_RS08690	COG1323	Belongs to the UPF0348 family
EL277_RS08695	COG2226	methyltransferase
EL277_RS08700	COG0799	negative regulation of ribosome biogenesis
EL277_RS08710	COG1713	HD superfamily hydrolase involved in NAD metabolism
EL277_RS08715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EL277_RS08720	COG1534	Rna-binding protein
EL277_RS08725	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EL277_RS08740	COG0668	transmembrane transport
EL277_RS08750	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EL277_RS08780	COG0438	transferase activity, transferring glycosyl groups
EL277_RS08785	COG0438	transferase activity, transferring glycosyl groups
EL277_RS08790	COG0653	protein targeting
EL277_RS08810	COG0201	protein transport
EL277_RS08815	COG1215	transferase activity, transferring glycosyl groups
EL277_RS08820	COG1442	glycosyl transferase family 8
EL277_RS08825	COG1442	glycosyl transferase family 8
EL277_RS08830	COG1442	glycosyl transferase family 8
EL277_RS08835	COG0438	transferase activity, transferring glycosyl groups
EL277_RS08850	COG1216	Glycosyl transferase, family 2
EL277_RS08850	COG1442	glycosyl transferase family 8
EL277_RS08900	COG3118	belongs to the thioredoxin family
EL277_RS08905	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EL277_RS08915	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL277_RS08925	COG1164	Oligoendopeptidase f
EL277_RS08930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EL277_RS08935	COG2264	protein methyltransferase activity
EL277_RS08940	COG1051	belongs to the nudix hydrolase family
EL277_RS08985	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EL277_RS08995	COG0582	viral genome integration into host DNA
EL277_RS09005	COG2946	Replication initiation factor
EL277_RS09045	COG1621	beta-fructofuranosidase activity
EL277_RS09050	COG0395	ABC-type sugar transport system, permease component
EL277_RS09065	COG1175	transmembrane transport
EL277_RS09075	COG1609	Transcriptional regulator
EL277_RS09105	COG3237	CsbD-like
EL277_RS09125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EL277_RS09135	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS09140	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL277_RS09145	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS09160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS09165	COG1940	carbohydrate kinase activity
EL277_RS09165	COG1846	Transcriptional regulator
EL277_RS09175	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EL277_RS09220	COG0512	Glutamine amidotransferase of anthranilate synthase
EL277_RS09225	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EL277_RS09245	COG1285	pathogenesis
EL277_RS09250	COG1178	ABC-type Fe3 transport system permease component
EL277_RS09270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EL277_RS09275	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EL277_RS09280	COG0704	Plays a role in the regulation of phosphate uptake
EL277_RS09295	COG5434	Belongs to the glycosyl hydrolase 28 family
EL277_RS09305	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EL277_RS09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EL277_RS09320	COG1132	(ABC) transporter
EL277_RS09325	COG1132	(ABC) transporter
EL277_RS09345	COG0708	Exodeoxyribonuclease III
EL277_RS09360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EL277_RS09365	COG2233	PERMEase
EL277_RS09385	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EL277_RS09390	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EL277_RS09395	COG1609	Transcriptional regulator
EL277_RS09400	COG1063	alcohol dehydrogenase
EL277_RS09405	COG0789	Transcriptional regulator
EL277_RS09410	COG1230	cation diffusion facilitator family transporter
EL277_RS09420	COG3201	nicotinamide mononucleotide transporter
EL277_RS09425	COG1174	glycine betaine transport
EL277_RS09450	COG1363	Peptidase, m42
EL277_RS09465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EL277_RS09470	COG4605	iron ion homeostasis
EL277_RS09475	COG4604	ABC transporter, ATP-binding protein
EL277_RS09480	COG4607	ABC-type enterochelin transport system periplasmic component
EL277_RS09485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EL277_RS09490	COG1187	pseudouridine synthase activity
EL277_RS09510	COG0517	IMP dehydrogenase activity
EL277_RS09520	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EL277_RS09535	COG0366	Alpha amylase catalytic
EL277_RS09545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS09545	COG1263	PTS System
EL277_RS09550	COG2188	Transcriptional regulator
EL277_RS09565	COG4608	Belongs to the ABC transporter superfamily
EL277_RS09570	COG0444	Belongs to the ABC transporter superfamily
EL277_RS09575	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EL277_RS09580	COG0601	transmembrane transport
EL277_RS09585	COG4166	transmembrane transport
EL277_RS09595	COG0366	Alpha amylase catalytic
EL277_RS09600	COG0395	ABC-type sugar transport system, permease component
EL277_RS09605	COG1175	transmembrane transport
EL277_RS09610	COG1653	transport
EL277_RS09615	COG3345	alpha-galactosidase
EL277_RS09620	COG2207	Transcriptional regulator
EL277_RS09625	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EL277_RS09625	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EL277_RS09745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EL277_RS09750	COG2137	regulation of response to DNA damage stimulus
EL277_RS09785	COG4221	oxidoreductase activity
EL277_RS09790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EL277_RS09795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EL277_RS09920	COG5263	repeat protein
EL277_RS09920	COG5632	N-Acetylmuramoyl-L-alanine amidase
EL277_RS09940	COG1546	Belongs to the CinA family
EL277_RS09940	COG1058	Belongs to the CinA family
EL277_RS09945	COG1316	TRANSCRIPTIONal
EL277_RS09955	COG0802	atpase or kinase
EL277_RS10020	COG1136	(ABC) transporter
EL277_RS10045	COG1253	flavin adenine dinucleotide binding
EL277_RS10060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EL277_RS10070	COG3480	Lon protease (S16) C-terminal proteolytic domain
EL277_RS10080	COG0742	ribosomal rna small subunit methyltransferase
EL277_RS10100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EL277_RS10105	COG1254	Belongs to the acylphosphatase family
EL277_RS10115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EL277_RS10125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EL277_RS10145	COG1564	THIamine pyrophosphokinase
EL277_RS10155	COG1162	GTPase activity
EL277_RS10185	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EL277_RS10190	COG0084	hydrolase, TatD family'
EL277_RS10210	COG0436	Aminotransferase
EL277_RS10220	COG0589	response to stress
EL277_RS10225	COG0561	phosphatase activity
EL277_RS10230	COG0252	asparaginase activity
EL277_RS10240	COG1609	Transcriptional regulator
EL277_RS10245	COG2197	response regulator
EL277_RS10250	COG4585	Histidine kinase
EL277_RS10255	COG0842	Transport permease protein
EL277_RS10260	COG1131	(ABC) transporter
EL277_RS10370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL277_RS10375	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL277_RS10380	COG0564	pseudouridine synthase activity
EL277_RS10390	COG0577	efflux transmembrane transporter activity
EL277_RS10400	COG0157	Belongs to the NadC ModD family
EL277_RS10415	COG1129	ABC transporter
EL277_RS10420	COG2188	Transcriptional regulator
EL277_RS10425	COG2723	6-phospho-beta-galactosidase activity
EL277_RS10430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EL277_RS10440	COG1447	Phosphotransferase system cellobiose-specific component IIA
EL277_RS10445	COG1454	alcohol dehydrogenase
EL277_RS10445	COG1012	belongs to the aldehyde dehydrogenase family
EL277_RS10455	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EL277_RS10465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EL277_RS10485	COG3623	hexulose-6-phosphate isomerase
EL277_RS10495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS10505	COG3037	sugar-specific permease SgaT UlaA
EL277_RS10515	COG1847	R3H domain protein
EL277_RS10520	COG0706	membrane insertase activity
EL277_RS10525	COG0594	ribonuclease P activity
EL277_RS10530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EL277_RS10565	COG4537	Required for transformation and DNA binding
EL277_RS10570	COG1459	type II secretion system
EL277_RS10575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EL277_RS10585	COG1063	alcohol dehydrogenase
EL277_RS10610	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EL277_RS10615	COG3759	membrane
EL277_RS10630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EL277_RS10630	COG0131	Imidazoleglycerol-phosphate dehydratase
EL277_RS10635	COG0534	Mate efflux family protein
EL277_RS10740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EL277_RS10755	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EL277_RS10760	COG1132	(ABC) transporter
EL277_RS10770	COG1132	(ABC) transporter
EL277_RS10780	COG1438	arginine binding
EL277_RS10785	COG0018	arginyl-trna synthetase
EL277_RS10800	COG0745	RESPONSE REGULATOR receiver
EL277_RS10805	COG5002	protein histidine kinase activity
EL277_RS10810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EL277_RS10815	COG0573	inorganic phosphate transmembrane transporter activity
EL277_RS10825	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EL277_RS10830	COG0704	Plays a role in the regulation of phosphate uptake
EL277_RS10850	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EL277_RS10870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EL277_RS10885	COG0697	spore germination
EL277_RS10890	COG4499	WXG100 protein secretion system (Wss), protein YukC
EL277_RS10890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EL277_RS10900	COG2217	Heavy metal translocating P-type atpase
EL277_RS10910	COG2226	methyltransferase
EL277_RS10930	COG0058	SHG alpha-glucan phosphorylase activity
EL277_RS10935	COG1640	4-alpha-glucanotransferase
EL277_RS10940	COG2182	Extracellular solute-binding protein
EL277_RS10945	COG1175	transmembrane transport
EL277_RS10950	COG3833	ABC-type maltose transport systems, permease component
EL277_RS10960	COG5521	maltodextrose utilization protein MalA
EL277_RS10965	COG1609	Transcriptional regulator
EL277_RS10975	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EL277_RS10980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EL277_RS11010	COG1476	TRANSCRIPTIONal
EL277_RS11025	COG0124	histidyl-tRNA synthetase
EL277_RS11045	COG2151	metal-sulfur cluster biosynthetic enzyme
EL277_RS11060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EL277_RS11065	COG3959	Transketolase, thiamine diphosphate binding domain
EL277_RS11080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EL277_RS11100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EL277_RS11135	COG0383	alpha-mannosidase activity
EL277_RS11145	COG3537	Alpha-1,2-mannosidase
EL277_RS11170	COG0549	Belongs to the carbamate kinase family
EL277_RS11175	COG1288	antiporter activity
EL277_RS11180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EL277_RS11190	COG3064	Membrane
EL277_RS11190	COG3583	domain protein
EL277_RS11190	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EL277_RS11210	COG1454	alcohol dehydrogenase
EL277_RS11215	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
EL277_RS11230	COG3716	PTS system mannose fructose sorbose family IID component
EL277_RS11240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EL277_RS11260	COG1070	Carbohydrate kinase
EL277_RS11275	COG0803	Belongs to the bacterial solute-binding protein 9 family
EL277_RS11275	COG3443	Belongs to the bacterial solute-binding protein 9 family
EL277_RS11280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EL277_RS11285	COG1121	(ABC) transporter
EL277_RS11290	COG1846	Transcriptional regulator
EL277_RS11295	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EL277_RS11305	COG1696	Membrane protein involved in D-alanine export
EL277_RS11320	COG2211	Major facilitator Superfamily
EL277_RS11350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EL277_RS11355	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EL277_RS11375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EL277_RS11385	COG1755	Isoprenylcysteine carboxyl methyltransferase
EL277_RS11390	COG5002	protein histidine kinase activity
EL277_RS11395	COG0745	RESPONSE REGULATOR receiver
EL277_RS11410	COG0542	response to heat
EL277_RS11415	COG4463	regulation of RNA biosynthetic process
EL277_RS11420	COG1116	anion transmembrane transporter activity
EL277_RS11425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EL277_RS11430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EL277_RS11450	COG0305	Participates in initiation and elongation during chromosome replication
EL277_RS11470	COG1040	competence protein
EL277_RS11475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EL277_RS11480	COG1739	Uncharacterized protein family UPF0029
EL277_RS11515	COG0052	Belongs to the universal ribosomal protein uS2 family
EL277_RS11520	COG3942	CHAP domain
EL277_RS11530	COG1792	Involved in formation and maintenance of cell shape
EL277_RS11535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EL277_RS11540	COG1122	ATPase activity
EL277_RS11545	COG1122	ATPase activity
EL277_RS11550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EL277_RS11560	COG0612	Peptidase, M16
EL277_RS11565	COG0612	Peptidase, M16
EL277_RS11570	COG2501	S4 domain
EL277_RS11580	COG0517	IMP dehydrogenase activity
EL277_RS11580	COG0516	GMP reductase activity
EL277_RS11585	COG0180	Tryptophanyl-tRNA synthetase
EL277_RS11590	COG0488	(ABC) transporter
EL277_RS11600	COG1511	domain protein
EL277_RS11610	COG1511	domain protein
EL277_RS11655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EL277_RS11660	COG1475	DNA binding