locus-tag	class	description
PCS8235_RS00020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PCS8235_RS00025	COG0285	dihydrofolate synthase activity
PCS8235_RS00035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PCS8235_RS00035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PCS8235_RS00045	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PCS8235_RS00060	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS00075	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS00075	COG3711	transcriptional antiterminator
PCS8235_RS00090	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS00105	COG0386	Belongs to the glutathione peroxidase family
PCS8235_RS00135	COG1028	Short-chain dehydrogenase reductase Sdr
PCS8235_RS00145	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PCS8235_RS00150	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS00155	COG3715	PTS system
PCS8235_RS00160	COG3716	PTS system mannose fructose sorbose family IID component
PCS8235_RS00175	COG1609	Transcriptional regulator
PCS8235_RS00205	COG4839	cell division protein FtsL
PCS8235_RS00210	COG0768	penicillin binding
PCS8235_RS00290	COG3344	reverse transcriptase
PCS8235_RS00305	COG0366	Alpha amylase catalytic
PCS8235_RS00310	COG4166	transmembrane transport
PCS8235_RS00345	COG3944	biosynthesis protein
PCS8235_RS00405	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PCS8235_RS00415	COG1088	dTDP-glucose 4,6-dehydratase activity
PCS8235_RS00430	COG4372	Transposase
PCS8235_RS00435	COG4166	transmembrane transport
PCS8235_RS00440	COG0366	Alpha amylase catalytic
PCS8235_RS00445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PCS8235_RS00470	COG0116	Belongs to the methyltransferase superfamily
PCS8235_RS00480	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PCS8235_RS00485	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS00535	COG4585	Histidine kinase
PCS8235_RS00540	COG2197	response regulator
PCS8235_RS00580	COG2801	Transposase and inactivated derivatives
PCS8235_RS00585	COG2801	Transposase and inactivated derivatives
PCS8235_RS00600	COG2213	PTS system mannitol-specific
PCS8235_RS00605	COG3711	transcriptional antiterminator
PCS8235_RS00610	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS00635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
PCS8235_RS00640	COG0681	Belongs to the peptidase S26 family
PCS8235_RS00665	COG1115	amino acid carrier protein
PCS8235_RS00690	COG0527	aspartate kinase activity
PCS8235_RS00695	COG1024	Enoyl-CoA hydratase
PCS8235_RS00700	COG1846	Transcriptional regulator
PCS8235_RS00710	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCS8235_RS00720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PCS8235_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
PCS8235_RS00730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PCS8235_RS00745	COG0439	Biotin carboxylase
PCS8235_RS00750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PCS8235_RS00785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PCS8235_RS00800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PCS8235_RS00810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PCS8235_RS00820	COG1461	Dihydroxyacetone kinase
PCS8235_RS00825	COG0028	Belongs to the TPP enzyme family
PCS8235_RS00830	COG0440	acetolactate synthase activity
PCS8235_RS00850	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PCS8235_RS00865	COG0765	amino acid transport
PCS8235_RS00890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PCS8235_RS00895	COG1882	Formate acetyltransferase
PCS8235_RS00920	COG1846	Transcriptional regulator
PCS8235_RS00920	COG1940	carbohydrate kinase activity
PCS8235_RS00925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS00935	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCS8235_RS00940	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS00945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS00945	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS00950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCS8235_RS00955	COG0569	domain protein
PCS8235_RS00975	COG1122	ATPase activity
PCS8235_RS00990	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PCS8235_RS00995	COG0671	phosphoesterase, PA-phosphatase related
PCS8235_RS01015	COG1132	(ABC) transporter
PCS8235_RS01035	COG1247	-acetyltransferase
PCS8235_RS01050	COG0504	CTP synthase activity
PCS8235_RS01055	COG1283	sodium-dependent phosphate transmembrane transporter activity
PCS8235_RS01080	COG0789	Transcriptional regulator
PCS8235_RS01085	COG0174	glutamine synthetase
PCS8235_RS01100	COG4974	Belongs to the 'phage' integrase family
PCS8235_RS01110	COG0732	type I restriction modification DNA specificity domain
PCS8235_RS01155	COG0484	heat shock protein binding
PCS8235_RS01175	COG0537	adenosine 5'-monophosphoramidase activity
PCS8235_RS01180	COG1131	(ABC) transporter
PCS8235_RS01205	COG3290	protein histidine kinase activity
PCS8235_RS01215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCS8235_RS01220	COG2274	protein secretion by the type I secretion system
PCS8235_RS01225	COG2274	protein secretion by the type I secretion system
PCS8235_RS01310	COG1266	CAAX protease self-immunity
PCS8235_RS01330	COG0195	Participates in both transcription termination and antitermination
PCS8235_RS01335	COG2740	Nucleic-acid-binding protein implicated in transcription termination
PCS8235_RS01410	COG0519	Catalyzes the synthesis of GMP from XMP
PCS8235_RS01420	COG0525	valine-tRNA ligase activity
PCS8235_RS01460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS01460	COG1263	PTS System
PCS8235_RS01460	COG2190	(PTS) system
PCS8235_RS01480	COG0456	acetyltransferase
PCS8235_RS01485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCS8235_RS01485	COG0072	phenylalanine-tRNA ligase activity
PCS8235_RS01500	COG3620	sequence-specific DNA binding
PCS8235_RS01520	COG1045	serine acetyltransferase
PCS8235_RS01530	COG0215	cysteine-tRNA ligase activity
PCS8235_RS01535	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PCS8235_RS01570	COG0577	efflux transmembrane transporter activity
PCS8235_RS01575	COG1136	(ABC) transporter
PCS8235_RS01580	COG0577	efflux transmembrane transporter activity
PCS8235_RS01585	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS01590	COG5002	protein histidine kinase activity
PCS8235_RS01595	COG0191	fructose-bisphosphate aldolase activity
PCS8235_RS01600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PCS8235_RS01605	COG0765	amino acid transport
PCS8235_RS01610	COG0765	amino acid transport
PCS8235_RS01615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS01625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PCS8235_RS01625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PCS8235_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS01685	COG1573	uracil-dna glycosylase
PCS8235_RS01695	COG1114	Component of the transport system for branched-chain amino acids
PCS8235_RS01700	COG1363	Peptidase, m42
PCS8235_RS01740	COG4555	ABC transporter
PCS8235_RS01770	COG1404	Belongs to the peptidase S8 family
PCS8235_RS01785	COG3775	system Galactitol-specific IIC component
PCS8235_RS01795	COG3250	beta-galactosidase activity
PCS8235_RS01820	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PCS8235_RS01840	COG0785	Cytochrome C biogenesis protein
PCS8235_RS01845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCS8235_RS01850	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCS8235_RS01850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCS8235_RS01855	COG4753	response regulator
PCS8235_RS01855	COG2207	Transcriptional regulator
PCS8235_RS01860	COG2972	Histidine kinase
PCS8235_RS01870	COG3064	Membrane
PCS8235_RS01875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCS8235_RS01890	COG1940	carbohydrate kinase activity
PCS8235_RS01910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PCS8235_RS01915	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
PCS8235_RS01925	COG0300	oxidoreductase activity
PCS8235_RS01940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PCS8235_RS01950	COG1187	pseudouridine synthase activity
PCS8235_RS01955	COG1217	gtp-binding protein TYPA
PCS8235_RS01975	COG1136	(ABC) transporter
PCS8235_RS01990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
PCS8235_RS02035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PCS8235_RS02060	COG1131	(ABC) transporter
PCS8235_RS02070	COG1126	abc transporter atp-binding protein
PCS8235_RS02075	COG1129	ABC transporter
PCS8235_RS02080	COG4215	(ABC) transporter
PCS8235_RS02090	COG1304	FMN binding
PCS8235_RS02095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PCS8235_RS02100	COG1304	FMN binding
PCS8235_RS02110	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PCS8235_RS02115	COG0352	thiamine-phosphate diphosphorylase activity
PCS8235_RS02125	COG4172	Belongs to the ABC transporter superfamily
PCS8235_RS02135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PCS8235_RS02150	COG0352	thiamine-phosphate diphosphorylase activity
PCS8235_RS02170	COG2217	Heavy metal translocating P-type atpase
PCS8235_RS02175	COG0028	Belongs to the TPP enzyme family
PCS8235_RS02185	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS02190	COG1482	cell wall glycoprotein biosynthetic process
PCS8235_RS02195	COG0733	neurotransmitter:sodium symporter activity
PCS8235_RS02215	COG2081	HI0933 family
PCS8235_RS02220	COG1307	EDD domain protein, DegV family
PCS8235_RS02230	COG2131	deaminase
PCS8235_RS02235	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PCS8235_RS02275	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PCS8235_RS02275	COG0617	tRNA 3'-terminal CCA addition
PCS8235_RS02275	COG0517	IMP dehydrogenase activity
PCS8235_RS02280	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PCS8235_RS02285	COG2884	Cell division ATP-binding protein ftsE
PCS8235_RS02290	COG2177	Part of the ABC transporter FtsEX involved in
PCS8235_RS02295	COG1263	PTS System
PCS8235_RS02295	COG2190	(PTS) system
PCS8235_RS02295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS02305	COG0513	Belongs to the DEAD box helicase family
PCS8235_RS02315	COG0167	dihydroorotate dehydrogenase activity
PCS8235_RS02325	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PCS8235_RS02330	COG4470	Protein conserved in bacteria
PCS8235_RS02345	COG0488	(ABC) transporter
PCS8235_RS02370	COG1837	Belongs to the UPF0109 family
PCS8235_RS02395	COG1328	CTP reductase activity
PCS8235_RS02395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PCS8235_RS02405	COG4443	Transcriptional Coactivator p15 (PC4)
PCS8235_RS02415	COG1268	BioY protein
PCS8235_RS02420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCS8235_RS02425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCS8235_RS02430	COG1136	(ABC) transporter
PCS8235_RS02435	COG0577	efflux transmembrane transporter activity
PCS8235_RS02440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCS8235_RS02440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCS8235_RS02465	COG4989	oxidoreductase activity
PCS8235_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
PCS8235_RS02505	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS02510	COG5002	protein histidine kinase activity
PCS8235_RS02530	COG0772	Belongs to the SEDS family
PCS8235_RS02535	COG0693	protein deglycase activity
PCS8235_RS02545	COG0187	DNA topoisomerase II activity
PCS8235_RS02585	COG0542	response to heat
PCS8235_RS02595	COG4703	Protein of unknown function (DUF1797)
PCS8235_RS02600	COG0765	amino acid transport
PCS8235_RS02605	COG1126	abc transporter atp-binding protein
PCS8235_RS02610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PCS8235_RS02620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PCS8235_RS02625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PCS8235_RS02640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PCS8235_RS02680	COG0268	Binds directly to 16S ribosomal RNA
PCS8235_RS02685	COG1072	(Pantothenic acid kinase))
PCS8235_RS02695	COG2813	Specifically methylates the guanine in position
PCS8235_RS02710	COG0295	cytidine deaminase activity
PCS8235_RS02715	COG1744	ABC transporter substrate-binding protein PnrA-like
PCS8235_RS02720	COG3845	ABC transporter
PCS8235_RS02725	COG4603	Belongs to the binding-protein-dependent transport system permease family
PCS8235_RS02730	COG1079	Belongs to the binding-protein-dependent transport system permease family
PCS8235_RS02755	COG0187	DNA topoisomerase II activity
PCS8235_RS02770	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCS8235_RS02775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
PCS8235_RS02780	COG4166	transmembrane transport
PCS8235_RS02815	COG0539	negative regulation of cytoplasmic translation
PCS8235_RS02820	COG1956	GAF domain-containing protein
PCS8235_RS02825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PCS8235_RS02840	COG0719	Fe-S assembly protein
PCS8235_RS02845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PCS8235_RS02855	COG0719	Fe-S assembly protein
PCS8235_RS02865	COG1686	Belongs to the peptidase S11 family
PCS8235_RS02870	COG0628	permease
PCS8235_RS02880	COG1349	DNA-binding transcription factor activity
PCS8235_RS02885	COG1105	Belongs to the carbohydrate kinase PfkB family
PCS8235_RS02890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCS8235_RS02890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
PCS8235_RS02890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS02900	COG1674	ftsk spoiiie
PCS8235_RS02900	COG0697	spore germination
PCS8235_RS02910	COG1104	cysteine desulfurase activity
PCS8235_RS02970	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
PCS8235_RS02980	COG1438	arginine binding
PCS8235_RS03000	COG0469	pyruvate kinase activity
PCS8235_RS03010	COG0582	viral genome integration into host DNA
PCS8235_RS03045	COG3689	TIGRFAM TIGR03943 family protein
PCS8235_RS03050	COG0701	Predicted permease
PCS8235_RS03060	COG2183	response to ionizing radiation
PCS8235_RS03090	COG1136	(ABC) transporter
PCS8235_RS03095	COG0577	efflux transmembrane transporter activity
PCS8235_RS03110	COG1982	Orn Lys Arg decarboxylase major
PCS8235_RS03125	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PCS8235_RS03145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PCS8235_RS03150	COG0561	phosphatase activity
PCS8235_RS03165	COG0583	DNA-binding transcription factor activity
PCS8235_RS03170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PCS8235_RS03175	COG0564	pseudouridine synthase activity
PCS8235_RS03180	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PCS8235_RS03195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PCS8235_RS03205	COG0470	DNA polymerase III
PCS8235_RS03245	COG0528	UMP kinase activity
PCS8235_RS03255	COG2996	Protein conserved in bacteria
PCS8235_RS03265	COG1702	phosphate starvation-inducible protein PhoH
PCS8235_RS03285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PCS8235_RS03290	COG1596	polysaccharide export
PCS8235_RS03290	COG1555	photosystem II stabilization
PCS8235_RS03295	COG2333	competence protein COMEC
PCS8235_RS03295	COG0658	competence protein
PCS8235_RS03300	COG1131	(ABC) transporter
PCS8235_RS03330	COG0543	2 iron, 2 sulfur cluster binding
PCS8235_RS03335	COG0167	dihydroorotate dehydrogenase activity
PCS8235_RS03340	COG5263	repeat protein
PCS8235_RS03340	COG4193	domain, Protein
PCS8235_RS03345	COG1293	RNA-binding protein homologous to eukaryotic snRNP
PCS8235_RS03355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
PCS8235_RS03365	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PCS8235_RS03370	COG0237	dephospho-CoA kinase activity
PCS8235_RS03375	COG2814	Major facilitator Superfamily
PCS8235_RS03385	COG0557	exoribonuclease II activity
PCS8235_RS03395	COG0500	methyltransferase
PCS8235_RS03395	COG3615	Tellurite resistance protein tehB
PCS8235_RS03410	COG4122	O-methyltransferase activity
PCS8235_RS03420	COG2801	Transposase and inactivated derivatives
PCS8235_RS03435	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PCS8235_RS03455	COG0494	nUDIX hydrolase
PCS8235_RS03465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PCS8235_RS03475	COG2176	DNA-directed DNA polymerase activity
PCS8235_RS03480	COG0584	glycerophosphoryl diester phosphodiesterase
PCS8235_RS03495	COG0785	Cytochrome C biogenesis protein
PCS8235_RS03500	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCS8235_RS03505	COG0531	amino acid
PCS8235_RS03510	COG3443	Belongs to the bacterial solute-binding protein 9 family
PCS8235_RS03510	COG0803	Belongs to the bacterial solute-binding protein 9 family
PCS8235_RS03540	COG2195	Cleaves the N-terminal amino acid of tripeptides
PCS8235_RS03560	COG0681	Belongs to the peptidase S26 family
PCS8235_RS03570	COG4509	Sortase family
PCS8235_RS03580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PCS8235_RS03585	COG1970	mechanosensitive ion channel activity
PCS8235_RS03595	COG4708	membrane
PCS8235_RS03605	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PCS8235_RS03620	COG1942	4-Oxalocrotonate Tautomerase
PCS8235_RS03625	COG1435	thymidine kinase activity
PCS8235_RS03635	COG2890	protein-(glutamine-N5) methyltransferase activity
PCS8235_RS03660	COG0741	lytic transglycosylase activity
PCS8235_RS03670	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCS8235_RS03695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCS8235_RS03700	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCS8235_RS03750	COG1597	lipid kinase activity
PCS8235_RS03790	COG1131	(ABC) transporter
PCS8235_RS03810	COG0772	Belongs to the SEDS family
PCS8235_RS03815	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PCS8235_RS03830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCS8235_RS03835	COG0358	DNA primase activity
PCS8235_RS03840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PCS8235_RS03845	COG2151	metal-sulfur cluster biosynthetic enzyme
PCS8235_RS03850	COG0438	transferase activity, transferring glycosyl groups
PCS8235_RS03855	COG0438	transferase activity, transferring glycosyl groups
PCS8235_RS03880	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCS8235_RS03890	COG4109	DRTGG domain
PCS8235_RS03895	COG0024	Methionine aminopeptidase
PCS8235_RS03910	COG0210	DNA helicase
PCS8235_RS03920	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PCS8235_RS03940	COG1104	cysteine desulfurase activity
PCS8235_RS03945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCS8235_RS03955	COG2357	RelA SpoT domain protein
PCS8235_RS03965	COG0564	pseudouridine synthase activity
PCS8235_RS03970	COG0280	phosphate acetyltransferase
PCS8235_RS04025	COG0196	riboflavin kinase activity
PCS8235_RS04030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PCS8235_RS04035	COG1307	EDD domain protein, DegV family
PCS8235_RS04045	COG0488	(ABC) transporter
PCS8235_RS04075	COG1523	belongs to the glycosyl hydrolase 13 family
PCS8235_RS04085	COG1012	belongs to the aldehyde dehydrogenase family
PCS8235_RS04090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PCS8235_RS04100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PCS8235_RS04110	COG0560	Phosphoserine phosphatase
PCS8235_RS04135	COG4974	Belongs to the 'phage' integrase family
PCS8235_RS04240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
PCS8235_RS04240	COG3583	domain protein
PCS8235_RS04245	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PCS8235_RS04270	COG0095	Lipoate-protein ligase
PCS8235_RS04275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCS8235_RS04280	COG0508	dehydrogenase complex catalyzes the overall conversion of
PCS8235_RS04285	COG0022	dehydrogenase e1 component
PCS8235_RS04290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PCS8235_RS04295	COG0534	Mate efflux family protein
PCS8235_RS04305	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PCS8235_RS04310	COG1051	belongs to the nudix hydrolase family
PCS8235_RS04325	COG1011	Hydrolase
PCS8235_RS04350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS04355	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
PCS8235_RS04360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCS8235_RS04365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PCS8235_RS04375	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS04390	COG3711	transcriptional antiterminator
PCS8235_RS04395	COG3684	Belongs to the aldolase LacD family
PCS8235_RS04450	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PCS8235_RS04455	COG0497	DNA recombination
PCS8235_RS04460	COG1438	arginine binding
PCS8235_RS04465	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
PCS8235_RS04500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PCS8235_RS04520	COG3764	Sortase (surface protein transpeptidase)
PCS8235_RS04525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PCS8235_RS04535	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PCS8235_RS04550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PCS8235_RS04555	COG5002	protein histidine kinase activity
PCS8235_RS04560	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS04565	COG1194	a g-specific adenine glycosylase
PCS8235_RS04580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PCS8235_RS04585	COG4684	Psort location CytoplasmicMembrane, score
PCS8235_RS04595	COG1827	regulation of RNA biosynthetic process
PCS8235_RS04625	COG0765	amino acid transport
PCS8235_RS04630	COG1126	abc transporter atp-binding protein
PCS8235_RS04635	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PCS8235_RS04640	COG0552	protein localization to endoplasmic reticulum
PCS8235_RS04645	COG0561	phosphatase activity
PCS8235_RS04650	COG0561	phosphatase activity
PCS8235_RS04655	COG1196	nuclear chromosome segregation
PCS8235_RS04680	COG1401	restriction endodeoxyribonuclease activity
PCS8235_RS04700	COG0066	3-isopropylmalate dehydratase activity
PCS8235_RS04710	COG0473	3-isopropylmalate dehydrogenase activity
PCS8235_RS04725	COG3142	Participates in the control of copper homeostasis
PCS8235_RS04730	COG2832	Protein of unknown function (DUF454)
PCS8235_RS04735	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PCS8235_RS04745	COG0758	DNA mediated transformation
PCS8235_RS04750	COG4750	Nucleotidyl transferase
PCS8235_RS04765	COG1063	alcohol dehydrogenase
PCS8235_RS04780	COG3475	LICD family
PCS8235_RS04785	COG3475	LICD family
PCS8235_RS04795	COG0505	Belongs to the CarA family
PCS8235_RS04810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PCS8235_RS04825	COG0488	(ABC) transporter
PCS8235_RS04830	COG0501	Belongs to the peptidase M48B family
PCS8235_RS04835	COG1704	LemA family
PCS8235_RS04850	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PCS8235_RS04865	COG1078	dGTPase activity
PCS8235_RS04890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCS8235_RS04895	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PCS8235_RS04900	COG1605	Chorismate mutase
PCS8235_RS04900	COG0077	Prephenate dehydratase
PCS8235_RS04905	COG0716	FMN binding
PCS8235_RS04910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PCS8235_RS04940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PCS8235_RS04990	COG0295	cytidine deaminase activity
PCS8235_RS05015	COG0395	ABC-type sugar transport system, permease component
PCS8235_RS05020	COG4209	transmembrane transport
PCS8235_RS05025	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PCS8235_RS05045	COG2801	Transposase and inactivated derivatives
PCS8235_RS05065	COG0577	efflux transmembrane transporter activity
PCS8235_RS05065	COG1136	(ABC) transporter
PCS8235_RS05075	COG1770	oligopeptidase
PCS8235_RS05080	COG0515	serine threonine protein kinase
PCS8235_RS05130	COG0402	S-adenosylhomocysteine deaminase activity
PCS8235_RS05140	COG1132	(ABC) transporter
PCS8235_RS05145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCS8235_RS05145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PCS8235_RS05180	COG1215	transferase activity, transferring glycosyl groups
PCS8235_RS05190	COG3475	LICD family
PCS8235_RS05200	COG0077	Prephenate dehydratase
PCS8235_RS05205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PCS8235_RS05210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
PCS8235_RS05220	COG0287	Prephenate dehydrogenase
PCS8235_RS05245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
PCS8235_RS05255	COG1131	(ABC) transporter
PCS8235_RS05295	COG3842	ATPase activity
PCS8235_RS05310	COG3527	Alpha-acetolactate decarboxylase
PCS8235_RS05315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
PCS8235_RS05320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS05325	COG0704	Plays a role in the regulation of phosphate uptake
PCS8235_RS05330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCS8235_RS05335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCS8235_RS05340	COG0581	inorganic phosphate transmembrane transporter activity
PCS8235_RS05345	COG0573	inorganic phosphate transmembrane transporter activity
PCS8235_RS05350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCS8235_RS05360	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
PCS8235_RS05360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCS8235_RS05365	COG0483	inositol monophosphate 1-phosphatase activity
PCS8235_RS05375	COG1393	Belongs to the ArsC family
PCS8235_RS05385	COG0647	UMP catabolic process
PCS8235_RS05395	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PCS8235_RS05455	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PCS8235_RS05475	COG1131	(ABC) transporter
PCS8235_RS05480	COG0826	peptidase U32
PCS8235_RS05485	COG0826	peptidase U32
PCS8235_RS05515	COG1132	(ABC) transporter
PCS8235_RS05520	COG1132	(ABC) transporter
PCS8235_RS05535	COG1129	ABC transporter
PCS8235_RS05575	COG2188	Transcriptional regulator
PCS8235_RS05580	COG0697	spore germination
PCS8235_RS05585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PCS8235_RS05600	COG0561	phosphatase activity
PCS8235_RS05625	COG0492	ferredoxin-NADP+ reductase activity
PCS8235_RS05635	COG1126	abc transporter atp-binding protein
PCS8235_RS05645	COG1393	Belongs to the ArsC family
PCS8235_RS05665	COG1272	protein, Hemolysin III
PCS8235_RS05695	COG0431	NADPH-dependent FMN reductase
PCS8235_RS05695	COG1053	succinate dehydrogenase
PCS8235_RS05695	COG3976	FMN-binding domain protein
PCS8235_RS05735	COG0656	L-ascorbic acid biosynthetic process
PCS8235_RS05740	COG0726	polysaccharide deacetylase
PCS8235_RS05785	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PCS8235_RS05820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PCS8235_RS05830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS05835	COG1126	abc transporter atp-binding protein
PCS8235_RS05850	COG0628	permease
PCS8235_RS05855	COG2706	6-phosphogluconolactonase activity
PCS8235_RS05920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PCS8235_RS05945	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
PCS8235_RS05960	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
PCS8235_RS05965	COG0626	cystathionine gamma-synthase activity
PCS8235_RS05970	COG1132	(ABC) transporter
PCS8235_RS05985	COG4166	transmembrane transport
PCS8235_RS05990	COG2244	polysaccharide biosynthetic process
PCS8235_RS05995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PCS8235_RS06000	COG3237	CsbD-like
PCS8235_RS06020	COG2827	Endonuclease containing a URI domain
PCS8235_RS06025	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PCS8235_RS06030	COG1098	S1 RNA binding domain
PCS8235_RS06040	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PCS8235_RS06045	COG0629	single-stranded DNA binding
PCS8235_RS06055	COG0017	Asparaginyl-tRNA synthetase
PCS8235_RS06065	COG0436	Aminotransferase
PCS8235_RS06095	COG0242	peptide deformylase activity
PCS8235_RS06100	COG0625	glutathione transferase activity
PCS8235_RS06110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PCS8235_RS06115	COG0488	(ABC) transporter
PCS8235_RS06120	COG0617	tRNA 3'-terminal CCA addition
PCS8235_RS06130	COG1307	EDD domain protein, DegV family
PCS8235_RS06150	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PCS8235_RS06165	COG0391	Required for morphogenesis under gluconeogenic growth conditions
PCS8235_RS06175	COG0251	oxidation-reduction process
PCS8235_RS06195	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PCS8235_RS06205	COG5263	repeat protein
PCS8235_RS06205	COG4193	domain, Protein
PCS8235_RS06215	COG3935	DnaD domain protein
PCS8235_RS06230	COG2226	methyltransferase
PCS8235_RS06235	COG3842	ATPase activity
PCS8235_RS06245	COG1335	isochorismatase
PCS8235_RS06260	COG0513	Belongs to the DEAD box helicase family
PCS8235_RS06265	COG2223	nitrite transmembrane transporter activity
PCS8235_RS06270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PCS8235_RS06275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PCS8235_RS06280	COG3442	glutamine amidotransferase
PCS8235_RS06285	COG0006	proline dipeptidase activity
PCS8235_RS06290	COG2801	Transposase and inactivated derivatives
PCS8235_RS06305	COG4720	Psort location CytoplasmicMembrane, score
PCS8235_RS06310	COG0351	phosphomethylpyrimidine kinase
PCS8235_RS06330	COG2824	Alkylphosphonate utilization operon protein PhnA
PCS8235_RS06350	COG0463	Glycosyl transferase, family 2
PCS8235_RS06355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PCS8235_RS06365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PCS8235_RS06370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PCS8235_RS06375	COG2384	SAM-dependent methyltransferase
PCS8235_RS06380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
PCS8235_RS06385	COG0204	Acyl-transferase
PCS8235_RS06400	COG2910	NAD(P)H-binding
PCS8235_RS06425	COG5002	protein histidine kinase activity
PCS8235_RS06430	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS06445	COG1959	2 iron, 2 sulfur cluster binding
PCS8235_RS06490	COG3590	peptidase
PCS8235_RS06505	COG0803	Belongs to the bacterial solute-binding protein 9 family
PCS8235_RS06510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PCS8235_RS06520	COG0577	efflux transmembrane transporter activity
PCS8235_RS06520	COG1136	(ABC) transporter
PCS8235_RS06555	COG3599	regulation of cell shape
PCS8235_RS06575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PCS8235_RS06595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PCS8235_RS06610	COG0768	penicillin binding
PCS8235_RS06625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PCS8235_RS06645	COG2731	YhcH YjgK YiaL family protein
PCS8235_RS06650	COG0395	ABC-type sugar transport system, permease component
PCS8235_RS06655	COG1175	transmembrane transport
PCS8235_RS06665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS06665	COG2190	(PTS) system
PCS8235_RS06665	COG1263	PTS System
PCS8235_RS06675	COG0673	inositol 2-dehydrogenase activity
PCS8235_RS06680	COG4409	exo-alpha-(2->6)-sialidase activity
PCS8235_RS06690	COG1175	transmembrane transport
PCS8235_RS06695	COG1653	transport
PCS8235_RS06720	COG3458	cephalosporin-C deacetylase activity
PCS8235_RS06725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PCS8235_RS06740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCS8235_RS06745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PCS8235_RS06750	COG0653	protein targeting
PCS8235_RS06760	COG1131	(ABC) transporter
PCS8235_RS06795	COG1484	DNA-dependent DNA replication
PCS8235_RS06810	COG1725	Transcriptional regulator
PCS8235_RS06815	COG1131	(ABC) transporter
PCS8235_RS06825	COG1668	transmembrane transport
PCS8235_RS06830	COG4152	abc transporter atp-binding protein
PCS8235_RS06845	COG1940	carbohydrate kinase activity
PCS8235_RS06850	COG1263	PTS System
PCS8235_RS06850	COG2190	(PTS) system
PCS8235_RS06850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS06860	COG1621	beta-fructofuranosidase activity
PCS8235_RS06865	COG1609	Transcriptional regulator
PCS8235_RS06875	COG3425	synthase
PCS8235_RS06900	COG2815	serine threonine protein kinase
PCS8235_RS06900	COG0515	serine threonine protein kinase
PCS8235_RS06905	COG0631	protein serine/threonine phosphatase activity
PCS8235_RS06910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PCS8235_RS06910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PCS8235_RS06920	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PCS8235_RS06930	COG0194	GDP metabolic process
PCS8235_RS06950	COG2226	methyltransferase
PCS8235_RS06955	COG0799	negative regulation of ribosome biogenesis
PCS8235_RS06965	COG1713	HD superfamily hydrolase involved in NAD metabolism
PCS8235_RS06970	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PCS8235_RS06975	COG1534	Rna-binding protein
PCS8235_RS06980	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PCS8235_RS06995	COG0668	transmembrane transport
PCS8235_RS07020	COG3118	belongs to the thioredoxin family
PCS8235_RS07025	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PCS8235_RS07035	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PCS8235_RS07050	COG1164	Oligoendopeptidase f
PCS8235_RS07055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PCS8235_RS07120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PCS8235_RS07130	COG1621	beta-fructofuranosidase activity
PCS8235_RS07135	COG0395	ABC-type sugar transport system, permease component
PCS8235_RS07140	COG1175	transmembrane transport
PCS8235_RS07150	COG1609	Transcriptional regulator
PCS8235_RS07155	COG3711	transcriptional antiterminator
PCS8235_RS07180	COG3237	CsbD-like
PCS8235_RS07200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PCS8235_RS07210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS07215	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCS8235_RS07220	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS07235	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS07240	COG1846	Transcriptional regulator
PCS8235_RS07240	COG1940	carbohydrate kinase activity
PCS8235_RS07250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
PCS8235_RS07295	COG0512	Glutamine amidotransferase of anthranilate synthase
PCS8235_RS07300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PCS8235_RS07320	COG1285	pathogenesis
PCS8235_RS07325	COG1178	ABC-type Fe3 transport system permease component
PCS8235_RS07355	COG5434	Belongs to the glycosyl hydrolase 28 family
PCS8235_RS07365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PCS8235_RS07370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PCS8235_RS07375	COG1132	(ABC) transporter
PCS8235_RS07380	COG1132	(ABC) transporter
PCS8235_RS07405	COG0708	Exodeoxyribonuclease III
PCS8235_RS07420	COG2233	PERMEase
PCS8235_RS07450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PCS8235_RS07455	COG1609	Transcriptional regulator
PCS8235_RS07460	COG1063	alcohol dehydrogenase
PCS8235_RS07475	COG1230	cation diffusion facilitator family transporter
PCS8235_RS07485	COG3201	nicotinamide mononucleotide transporter
PCS8235_RS07490	COG1732	Glycine betaine
PCS8235_RS07515	COG1363	Peptidase, m42
PCS8235_RS07530	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PCS8235_RS07535	COG4605	iron ion homeostasis
PCS8235_RS07540	COG4604	ABC transporter, ATP-binding protein
PCS8235_RS07545	COG4607	ABC-type enterochelin transport system periplasmic component
PCS8235_RS07555	COG1187	pseudouridine synthase activity
PCS8235_RS07575	COG0517	IMP dehydrogenase activity
PCS8235_RS07585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PCS8235_RS07600	COG0366	Alpha amylase catalytic
PCS8235_RS07605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS07605	COG1263	PTS System
PCS8235_RS07610	COG2188	Transcriptional regulator
PCS8235_RS07615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCS8235_RS07640	COG2252	PERMEase
PCS8235_RS07645	COG0561	phosphatase activity
PCS8235_RS07650	COG1064	alcohol dehydrogenase
PCS8235_RS07660	COG3715	PTS system
PCS8235_RS07665	COG3716	PTS system mannose fructose sorbose family IID component
PCS8235_RS07670	COG3579	cysteine-type endopeptidase activity
PCS8235_RS07675	COG1187	pseudouridine synthase activity
PCS8235_RS07680	COG2261	transglycosylase associated protein
PCS8235_RS07685	COG2309	aminopeptidase activity
PCS8235_RS07705	COG2176	DNA-directed DNA polymerase activity
PCS8235_RS07730	COG1523	belongs to the glycosyl hydrolase 13 family
PCS8235_RS07740	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PCS8235_RS07745	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS07755	COG0750	zinc metalloprotease
PCS8235_RS07760	COG4589	Belongs to the CDS family
PCS8235_RS07765	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PCS8235_RS07795	COG0495	leucyl-tRNA aminoacylation
PCS8235_RS07810	COG1882	Formate acetyltransferase
PCS8235_RS07815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS07820	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS07825	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCS8235_RS07835	COG1349	DNA-binding transcription factor activity
PCS8235_RS07840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCS8235_RS07855	COG1840	ABC-type Fe3 transport system, periplasmic component
PCS8235_RS07865	COG1178	ABC-type Fe3 transport system permease component
PCS8235_RS07885	COG3830	Belongs to the UPF0237 family
PCS8235_RS07895	COG0202	RNA polymerase activity
PCS8235_RS07900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PCS8235_RS07910	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PCS8235_RS07920	COG0201	protein transport
PCS8235_RS07935	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PCS8235_RS07975	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PCS8235_RS08000	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PCS8235_RS08035	COG0602	queuosine metabolic process
PCS8235_RS08065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PCS8235_RS08075	COG0285	dihydrofolate synthase activity
PCS8235_RS08100	COG1393	Belongs to the ArsC family
PCS8235_RS08110	COG0006	proline dipeptidase activity
PCS8235_RS08115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PCS8235_RS08140	COG2818	Glycosylase
PCS8235_RS08160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PCS8235_RS08160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PCS8235_RS08195	COG1780	Probably involved in ribonucleotide reductase function
PCS8235_RS08205	COG2207	Transcriptional regulator
PCS8235_RS08205	COG4753	response regulator
PCS8235_RS08210	COG2972	Histidine kinase
PCS8235_RS08230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PCS8235_RS08235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PCS8235_RS08240	COG1464	Belongs to the NlpA lipoprotein family
PCS8235_RS08245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS08285	COG1396	sequence-specific DNA binding
PCS8235_RS08330	COG0438	transferase activity, transferring glycosyl groups
PCS8235_RS08355	COG1214	PFAM Peptidase M22, glycoprotease
PCS8235_RS08390	COG0445	tRNA wobble uridine modification
PCS8235_RS08495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PCS8235_RS08500	COG0577	efflux transmembrane transporter activity
PCS8235_RS08500	COG1136	(ABC) transporter
PCS8235_RS08525	COG1760	l-serine dehydratase
PCS8235_RS08530	COG1760	l-serine dehydratase
PCS8235_RS08535	COG0546	phosphoglycolate phosphatase activity
PCS8235_RS08560	COG1695	Transcriptional regulator
PCS8235_RS08590	COG1653	transport
PCS8235_RS08595	COG0395	ABC-type sugar transport system, permease component
PCS8235_RS08600	COG4209	transmembrane transport
PCS8235_RS08620	COG5002	protein histidine kinase activity
PCS8235_RS08650	COG1215	transferase activity, transferring glycosyl groups
PCS8235_RS08655	COG0569	domain protein
PCS8235_RS08660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PCS8235_RS08685	COG1937	Protein conserved in bacteria
PCS8235_RS08690	COG2514	catechol 2,3-dioxygenase activity
PCS8235_RS08700	COG2222	sugar isomerase
PCS8235_RS08710	COG3716	PTS system mannose fructose sorbose family IID component
PCS8235_RS08715	COG3715	PTS system
PCS8235_RS08720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS08740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PCS8235_RS08755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PCS8235_RS08760	COG0151	Belongs to the GarS family
PCS8235_RS08765	COG0138	bifunctional purine biosynthesis protein purh
PCS8235_RS08775	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PCS8235_RS08780	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PCS8235_RS08785	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PCS8235_RS08790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PCS8235_RS08800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PCS8235_RS08805	COG2274	protein secretion by the type I secretion system
PCS8235_RS08825	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PCS8235_RS08840	COG0436	Aminotransferase
PCS8235_RS08845	COG2855	membrane
PCS8235_RS08855	COG1832	CoA-binding protein
PCS8235_RS08860	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCS8235_RS08860	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PCS8235_RS08880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PCS8235_RS08895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PCS8235_RS08905	COG0756	dUTP diphosphatase activity
PCS8235_RS08935	COG3335	DDE superfamily endonuclease
PCS8235_RS08980	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PCS8235_RS08985	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
PCS8235_RS09010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PCS8235_RS09015	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PCS8235_RS09025	COG0012	GTP binding
PCS8235_RS09035	COG0592	DNA-directed DNA polymerase activity
PCS8235_RS09045	COG1475	DNA binding
PCS8235_RS09050	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PCS8235_RS09095	COG1511	domain protein
PCS8235_RS09125	COG0488	(ABC) transporter
PCS8235_RS09130	COG0180	Tryptophanyl-tRNA synthetase
PCS8235_RS09135	COG0516	GMP reductase activity
PCS8235_RS09135	COG0517	IMP dehydrogenase activity
PCS8235_RS09145	COG2501	S4 domain
PCS8235_RS09150	COG0612	Peptidase, M16
PCS8235_RS09155	COG0612	Peptidase, M16
PCS8235_RS09165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PCS8235_RS09170	COG1122	ATPase activity
PCS8235_RS09175	COG1122	ATPase activity
PCS8235_RS09180	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PCS8235_RS09185	COG1792	Involved in formation and maintenance of cell shape
PCS8235_RS09195	COG3942	CHAP domain
PCS8235_RS09230	COG1739	Uncharacterized protein family UPF0029
PCS8235_RS09235	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PCS8235_RS09240	COG1040	competence protein
PCS8235_RS09260	COG0305	Participates in initiation and elongation during chromosome replication
PCS8235_RS09280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
PCS8235_RS09285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
PCS8235_RS09290	COG1116	anion transmembrane transporter activity
PCS8235_RS09295	COG4463	regulation of RNA biosynthetic process
PCS8235_RS09300	COG0542	response to heat
PCS8235_RS09320	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS09325	COG5002	protein histidine kinase activity
PCS8235_RS09330	COG1755	Isoprenylcysteine carboxyl methyltransferase
PCS8235_RS09335	COG0366	Alpha amylase catalytic
PCS8235_RS09340	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PCS8235_RS09365	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PCS8235_RS09370	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PCS8235_RS09385	COG3344	reverse transcriptase
PCS8235_RS09405	COG1696	Membrane protein involved in D-alanine export
PCS8235_RS09415	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PCS8235_RS09420	COG1846	Transcriptional regulator
PCS8235_RS09425	COG1121	(ABC) transporter
PCS8235_RS09430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PCS8235_RS09435	COG0803	Belongs to the bacterial solute-binding protein 9 family
PCS8235_RS09435	COG3443	Belongs to the bacterial solute-binding protein 9 family
PCS8235_RS09455	COG1070	Carbohydrate kinase
PCS8235_RS09475	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PCS8235_RS09485	COG3716	PTS system mannose fructose sorbose family IID component
PCS8235_RS09505	COG1454	alcohol dehydrogenase
PCS8235_RS09515	COG3064	Membrane
PCS8235_RS09515	COG3583	domain protein
PCS8235_RS09515	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PCS8235_RS09525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PCS8235_RS09530	COG1288	antiporter activity
PCS8235_RS09535	COG0549	Belongs to the carbamate kinase family
PCS8235_RS09565	COG0383	alpha-mannosidase activity
PCS8235_RS09615	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PCS8235_RS09635	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS09650	COG3959	Transketolase, thiamine diphosphate binding domain
PCS8235_RS09655	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PCS8235_RS09670	COG2151	metal-sulfur cluster biosynthetic enzyme
PCS8235_RS09700	COG1476	TRANSCRIPTIONal
PCS8235_RS09735	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PCS8235_RS09745	COG1609	Transcriptional regulator
PCS8235_RS09750	COG5521	maltodextrose utilization protein MalA
PCS8235_RS09755	COG3833	ABC-type maltose transport systems, permease component
PCS8235_RS09760	COG1175	transmembrane transport
PCS8235_RS09765	COG2182	Extracellular solute-binding protein
PCS8235_RS09770	COG1640	4-alpha-glucanotransferase
PCS8235_RS09775	COG0058	SHG alpha-glucan phosphorylase activity
PCS8235_RS09795	COG2226	methyltransferase
PCS8235_RS09805	COG2217	Heavy metal translocating P-type atpase
PCS8235_RS09815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PCS8235_RS09815	COG4499	WXG100 protein secretion system (Wss), protein YukC
PCS8235_RS09820	COG0697	spore germination
PCS8235_RS09835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PCS8235_RS09845	COG1210	Utp--glucose-1-phosphate uridylyltransferase
PCS8235_RS09870	COG0704	Plays a role in the regulation of phosphate uptake
PCS8235_RS09875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
PCS8235_RS09885	COG0573	inorganic phosphate transmembrane transporter activity
PCS8235_RS09890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
PCS8235_RS09900	COG0745	RESPONSE REGULATOR receiver
PCS8235_RS09920	COG1438	arginine binding
PCS8235_RS09930	COG1132	(ABC) transporter
PCS8235_RS09940	COG1132	(ABC) transporter
PCS8235_RS09945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
PCS8235_RS10060	COG0534	Mate efflux family protein
PCS8235_RS10065	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
PCS8235_RS10065	COG0131	Imidazoleglycerol-phosphate dehydratase
PCS8235_RS10080	COG3759	membrane
PCS8235_RS10085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PCS8235_RS10110	COG1063	alcohol dehydrogenase
PCS8235_RS10120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PCS8235_RS10125	COG1459	type II secretion system
PCS8235_RS10130	COG4537	Required for transformation and DNA binding
PCS8235_RS10190	COG0706	membrane insertase activity
PCS8235_RS10195	COG1847	R3H domain protein
PCS8235_RS10205	COG3037	sugar-specific permease SgaT UlaA
PCS8235_RS10215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
PCS8235_RS10225	COG3623	hexulose-6-phosphate isomerase
PCS8235_RS10245	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PCS8235_RS10255	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PCS8235_RS10265	COG1454	alcohol dehydrogenase
PCS8235_RS10265	COG1012	belongs to the aldehyde dehydrogenase family
PCS8235_RS10270	COG1447	Phosphotransferase system cellobiose-specific component IIA
PCS8235_RS10280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PCS8235_RS10285	COG2723	6-phospho-beta-galactosidase activity
PCS8235_RS10290	COG2188	Transcriptional regulator
PCS8235_RS10295	COG4133	protoheme IX ABC transporter activity
PCS8235_RS10305	COG0157	Belongs to the NadC ModD family
PCS8235_RS10320	COG0577	efflux transmembrane transporter activity
PCS8235_RS10330	COG0564	pseudouridine synthase activity
PCS8235_RS10335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PCS8235_RS10360	COG4608	Belongs to the ABC transporter superfamily
PCS8235_RS10365	COG0444	Belongs to the ABC transporter superfamily
PCS8235_RS10370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PCS8235_RS10375	COG0601	transmembrane transport
PCS8235_RS10380	COG4166	transmembrane transport
PCS8235_RS10390	COG0366	Alpha amylase catalytic
PCS8235_RS10400	COG0395	ABC-type sugar transport system, permease component
PCS8235_RS10405	COG1175	transmembrane transport
PCS8235_RS10410	COG1653	transport
PCS8235_RS10415	COG3345	alpha-galactosidase
PCS8235_RS10420	COG2207	Transcriptional regulator
PCS8235_RS10425	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
PCS8235_RS10425	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
PCS8235_RS10545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PCS8235_RS10580	COG4221	oxidoreductase activity
PCS8235_RS10585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PCS8235_RS10590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PCS8235_RS10620	COG1132	(ABC) transporter
PCS8235_RS10710	COG5632	N-Acetylmuramoyl-L-alanine amidase
PCS8235_RS10710	COG5263	repeat protein
PCS8235_RS10730	COG1316	TRANSCRIPTIONal
PCS8235_RS10740	COG0802	atpase or kinase
PCS8235_RS10770	COG1136	(ABC) transporter
PCS8235_RS10805	COG1253	flavin adenine dinucleotide binding
PCS8235_RS10820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PCS8235_RS10830	COG3480	Lon protease (S16) C-terminal proteolytic domain
PCS8235_RS10835	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PCS8235_RS10840	COG0742	ribosomal rna small subunit methyltransferase
PCS8235_RS10855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PCS8235_RS10860	COG1254	Belongs to the acylphosphatase family
PCS8235_RS10870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PCS8235_RS10880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PCS8235_RS10895	COG1564	THIamine pyrophosphokinase
PCS8235_RS10905	COG1162	GTPase activity
PCS8235_RS10945	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PCS8235_RS10950	COG0084	hydrolase, TatD family'
PCS8235_RS10970	COG0436	Aminotransferase
PCS8235_RS10980	COG0589	response to stress
PCS8235_RS10985	COG0561	phosphatase activity
PCS8235_RS10990	COG0252	asparaginase activity
PCS8235_RS11000	COG1609	Transcriptional regulator
PCS8235_RS11005	COG2197	response regulator
PCS8235_RS11010	COG4585	Histidine kinase
PCS8235_RS11015	COG0842	Transport permease protein
PCS8235_RS11020	COG1131	(ABC) transporter
PCS8235_RS11210	COG2801	Transposase and inactivated derivatives
PCS8235_RS11215	COG2801	Transposase and inactivated derivatives
PCS8235_RS11225	COG3711	transcriptional antiterminator
PCS8235_RS11245	COG1126	abc transporter atp-binding protein
PCS8235_RS11250	COG1242	4 iron, 4 sulfur cluster binding
PCS8235_RS11255	COG1242	4 iron, 4 sulfur cluster binding
PCS8235_RS11285	COG2826	transposase and inactivated derivatives, IS30 family
PCS8235_RS11295	COG0765	amino acid transport
PCS8235_RS11310	COG0494	nUDIX hydrolase
PCS8235_RS11320	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
PCS8235_RS11330	COG2801	Transposase and inactivated derivatives
PCS8235_RS11385	COG0686	Belongs to the AlaDH PNT family
PCS8235_RS11390	COG0686	Belongs to the AlaDH PNT family
PCS8235_RS11400	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PCS8235_RS11435	COG0366	Alpha amylase catalytic
PCS8235_RS11500	COG0582	viral genome integration into host DNA
PCS8235_RS11630	COG1132	(ABC) transporter
PCS8235_RS11780	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PCS8235_RS11860	COG2801	Transposase and inactivated derivatives
PCS8235_RS11870	COG3335	DDE superfamily endonuclease
PCS8235_RS11930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PCS8235_RS12015	COG3335	DDE superfamily endonuclease