locus_tag old_locus_tag gene Name start end strand product note type ID NCBI spr0001 spr0001 dnaA dnaA 1 1362 + chromosomal replication initiation protein binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication%3B can also affect transcription of multiple genes including itself. gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=spr0001 spr0002 spr0002 dnaN dnaN 1521 2657 + DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=spr0002 spr0003 spr0003 spr0003 2722 2916 + hypothetical protein gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=spr0003 spr0004 spr0004 ychF ychF 3000 4115 + GTP-dependent nucleic acid-binding protein EngD translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=spr0004 spr0005 spr0005 pth pth 4186 4755 + peptidyl-tRNA hydrolase Enables the recycling of peptidyl-tRNAs produced at termination of translation gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=spr0005 spr0006 spr0006 mfd mfd 4756 8265 + transcription-repair coupling factor gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=spr0006 spr0007 spr0007 spr0007 8323 8589 + S4 domain-containing protein gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=spr0007 spr0008 spr0008 spr0008 8582 8950 + hypothetical protein gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=spr0008 spr0009 spr0009 spr0009 9001 10338 + hypothetical protein gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=spr0009 spr0010 spr0010 spr0010 10335 11612 + hypothetical protein cell cycle protein of the MesJ/Ycf62 family gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=spr0010 spr0011 spr0011 hgt hgt 11616 12158 + hypoxanthine-guanine phosphoribosyltransferase Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine%2C respectively gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=spr0011 spr0012 spr0012 ftsH ftsH 12174 14132 + cell division protein FtsH gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=spr0012 spr0013 spr0013 comX1 comX1 14254 14733 + competence-specific global transcription modulator sigma factor gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=spr0013 spr0014 spr0014 transposase_A transposase_A 20207 20554 + transposase gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=spr0014 spr0016 spr0016 transposase_B transposase_B 20733 21071 + transposase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=spr0016 spr0017 spr0017 IS1167-truncation IS1167-truncation 21106 21422 - gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=spr0017 spr0018 spr0018 IS1167-truncation IS1167-truncation 21455 21604 - gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=spr0018 spr0020 spr0020 spr0020 22162 22404 + hypothetical protein gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=spr0020 spr0021 spr0021 purA purA 22635 23921 + adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=spr0021 spr0022 spr0022 spr0022 24122 24589 + cytidine/deoxycytidylate deaminase cytidine/deoxycytidylate deaminase gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=spr0022 spr0023 spr0023 dut dut 24776 25219 + deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=spr0023 spr0024 spr0024 spr0024 25158 25736 + hypothetical protein Similar to phosphoglycerate mutase gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=spr0024 spr0025 spr0025 radA radA 25849 27111 + DNA repair protein RadA Sms%3B stabilizes the strand-invasion intermediate during the DNA repair%3B involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=spr0025 spr0026 spr0026 spr0026 27115 27681 + hypothetical protein gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=spr0026 spr0027 spr0027 spr0027 27706 28365 + gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=spr0027 spr0028 spr0028 prsA prsA 28583 29602 + ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=spr0028 spr0030 spr0030 spr0030 30143 30481 - hypothetical protein gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=spr0030 spr0031 spr0031 spr0031 30700 31053 - hypothetical protein gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=spr0031 spr0032 spr0032 polA polA 31306 33939 + DNA polymerase I has 3'-5' exonuclease%2C 5'-3' exonuclease and 5'-3'polymerase activities%2C primarily functions to fill gaps during DNA replication and repair gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=spr0032 spr0033 spr0033 spr0033 34024 34461 + hypothetical protein gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=spr0033 spr0034 spr0034 spr0034 34652 35674 - hypothetical protein gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=spr0034 spr0035 spr0035 aspC aspC 35811 36980 + aromatic amino acid aminotransferase catalyzes the transamination of the aromatic amino acid forming a ketoacid%3B first step in aromatic amino acid degradation in lactococci gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=spr0035 spr0036 spr0036 recO recO 36977 37747 + DNA repair protein RecO involved in DNA repair and RecFOR pathway recombination%3B RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=spr0036 spr0037 spr0037 plsX plsX 37744 38736 + glycerol-3-phosphate acyltransferase PlsX involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsY gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=spr0037 spr0038 spr0038 acpP acpP 38742 38975 + acyl carrier protein gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=spr0038 spr0040 spr0040 thmA thmA 39514 39744 + amphipathic pore-forming protein gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=spr0040 spr0041 spr0041 IS1167 IS1167 40224 40991 - transposase gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=spr0041 spr0042 spr0042 IS1167 IS1167 40982 41500 - transposase gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=spr0042 spr0043 spr0043 comA comA 41902 44055 + competence factor transporting ATP-binding protein/permease ComA Competence induced protein ComA%2C with ComB is responsible for secretion of CSP gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=spr0043 spr0044 spr0044 comB comB 44068 45417 + competence factor transport protein ComB Competence induced protein ComB%2C with ComA is responsible for secretion of CSP gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=spr0044 spr0045 spr0045 purC purC 45545 46294 + phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=spr0045 spr0046 spr0046 purL purL 46493 50221 + phosphoribosylformylglycinamidine synthase gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=spr0046 spr0047 spr0047 purF purF 50314 51756 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=spr0047 spr0048 spr0048 purM purM 51793 52815 + phosphoribosylaminoimidazole synthetase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=spr0048 spr0049 spr0049 purN purN 52812 53357 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=spr0049 spr0050 spr0050 vanZ vanZ 53441 53950 + VanZ protein gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=spr0050 spr0051 spr0051 purH purH 53954 55522 + bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase involved in de novo purine biosynthesis gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=spr0051 spr0052 spr0052 purD purD 55644 56906 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=spr0052 spr0052a spr0052a spr0052a 56979 57146 + hypothetical protein gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=spr0052a spr0053 spr0053 purE purE 57276 57797 + phosphoribosylaminoimidazole carboxylase catalytic subunit Catalyzes a step in the de novo purine nucleotide biosynthetic pathway gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=spr0053 spr0054 spr0054 purK purK 57724 58875 + phosphoribosylaminoimidazole carboxylase ATPase subunit With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=spr0054 spr0055 spr0055 spr0055 58885 59112 + hypothetical protein gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=spr0055 spr0056 spr0056 purB purB 59175 60473 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=spr0056 spr0057 spr0057 strH strH 60528 64466 - beta-N-acetylhexosaminidase gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=spr0057 spr0058 spr0058 spr0058 64781 65539 - hypothetical protein Similar to transcriptional regulator (GntR family) gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=spr0058 spr0059 spr0059 bgaC bgaC 65845 67632 + beta-galactosidase 3 gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=spr0059 spr0060 spr0060 PTS-EIIB PTS-EIIB 67629 68105 + PTS system transporter subunit IIB gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=spr0060 spr0061 spr0061 PTS-EIIC PTS-EIIC 68133 69038 + PTS system transporter subunit IIC gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=spr0061 spr0062 spr0062 PTS-EIID PTS-EIID 69010 69840 + PTS system transporter subunit IID gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=spr0062 spr0063 spr0063 PTS-EII PTS-EII 69847 70251 + PTS system transporter subunit IIA gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=spr0063 spr0064 spr0064 agaS agaS 70549 71715 + sugar isomerase domain-containing protein gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=spr0064 spr0065 spr0065 galM galM 71831 72868 + aldose 1-epimerase gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=spr0065 spr0066 spr0066 spr0066 73075 73929 + hypothetical protein gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=spr0066 spr0067 spr0067 spr0067 74079 74336 + hypothetical protein gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=spr0067 spr0068 spr0068 spr0068 75311 76075 + hypothetical protein Similar to uridine phosphorylase gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=spr0068 spr0069 spr0069 spr0069 76547 76705 + hypothetical protein gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=spr0069 spr0070 spr0070 trkH trkH 76686 78065 + Trk transporter membrane-spanning protein gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=spr0070 spr0071 spr0071 trkA trkA 78058 78744 + Trk transporter NAD+ binding protein gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=spr0071 spr0072 spr0072 spr0072 79054 80070 + gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=spr0072 spr0075 spr0075 spr0075 80186 83671 + cell wall surface anchor family protein Similar to cell wall-associated serine proteinase gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=spr0075 spr0076 spr0076 rr08 rr08 83838 84536 + DNA-binding response regulator gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=spr0076 spr0077 spr0077 hk08 hk08 84533 85585 + sensor histidine kinase gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=spr0077 spr0078 spr0078 rpsD rpsD 85780 86391 + 30S ribosomal protein S4 primary rRNA binding protein%3B nucleates 30S assembly%3B involved in translational accuracy with proteins S5 and S12%3B interacts with protein S5%3B involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA%3B interacts with transcription complex and functions similar to protein NusA in antitermination gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=spr0078 spr0079 spr0079 transposase_A transposase_A 86559 86735 + degenerative transposase gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=spr0079 spr0080 spr0080 spr0080 87044 87313 + hypothetical protein gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=spr0080 spr0081 spr0081 ABC-MSP ABC-MSP 87777 88736 + ABC transporter permease gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=spr0081 spr0082 spr0082 ABC-MSP ABC-MSP 88750 89673 + ABC transporter permease gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=spr0082 spr0083 spr0083 ABC-SBP ABC-SBP 89862 91406 + ABC transporter substrate-binding protein gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=spr0083 spr0084 spr0084 spr0084 91678 92664 + hypothetical protein gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=spr0084 spr0085 spr0085 spr0085 92633 93646 + hypothetical protein gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=spr0085 spr0086 spr0086 spr0086 93718 94782 - hypothetical protein gene gene87 http://www.ncbi.nlm.nih.gov/gene/?term=spr0086 spr0087 spr0087 spr0087 94845 95807 - hypothetical protein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=spr0087 spr0088 spr0088 spr0088 95749 96342 - hypothetical protein gene gene89 http://www.ncbi.nlm.nih.gov/gene/?term=spr0088 spr0089 spr0089 spr0089 96329 96655 - hypothetical protein gene gene90 http://www.ncbi.nlm.nih.gov/gene/?term=spr0089 spr0090 spr0090 spr0090 96794 97960 - transporter gene gene91 http://www.ncbi.nlm.nih.gov/gene/?term=spr0090 spr0091 spr0091 spr0091 98018 99175 + hypothetical protein sugar transferase related protein gene gene92 http://www.ncbi.nlm.nih.gov/gene/?term=spr0091 spr0092 spr0092 capD capD 99217 101067 + capsule polysaccharide biosynthesis protein CapD gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=spr0092 spr0093 spr0093 gph gph 101463 102095 - phosphoglycolate phosphatase gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=spr0093 spr0094 spr0094 sdaA sdaA 102117 102989 - L-serine dehydratase subunit alpha gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=spr0094 spr0095 spr0095 sdaB sdaB 102998 103669 - L-serine dehydratase subunit beta gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=spr0095 spr0096 spr0096 spr0096 103911 104414 + LysM domain-containing protein gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=spr0096 spr0098 spr0098 spr0098 105242 105490 + bacteriocin gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=spr0098 spr0099 spr0099 ABC-MSP ABC-MSP 105545 107653 + amino acid ABC transporter permease gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=spr0099 spr0100 spr0100 ABC-NBD ABC-NBD 107650 108291 + amino acid ABC transporter ATP-binding protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=spr0100 spr0101 spr0101 ABC-SBP ABC-SBP 108506 109303 + amino acid ABC transporter substrate-binding protein gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=spr0101 spr0102 spr0102 argG argG 109269 110516 + argininosuccinate synthase catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis%2C AMP-forming gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=spr0102 spr0103 spr0103 argH argH 110545 111936 + argininosuccinate lyase catalyzes the formation of arginine from (N-L-arginino)succinate gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=spr0103 spr0104 spr0104 spr0104 112225 113124 - hypothetical protein gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=spr0104 spr0106 spr0106 spr0106 113839 115773 + ABC transporter permease/ATP-binding protein Similar to competence factor transporting ATP-binding/permease ComA gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=spr0106 spr0107 spr0107 spr0107 115766 116233 + hypothetical protein gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=spr0107 spr0108 spr0108 spr0108 116230 117582 + hypothetical protein Similar to ComB protein gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=spr0108 spr0109 spr0109 spr0109 117728 118108 + hypothetical protein gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=spr0109 spr0110 spr0110 spr0110 118611 118931 - hypothetical protein gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=spr0110 spr0111 spr0111 spr0111 119688 120059 + hypothetical protein gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=spr0111 spr0112 spr0112 spr0112 120067 120279 + hypothetical protein gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=spr0112 spr0113 spr0113 spr0113 121084 122142 + hypothetical protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=spr0113 spr0114 spr0114 spr0114 122441 123433 + hypothetical protein gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=spr0114 spr0115 spr0115 spr0115 123810 124184 + hypothetical protein gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=spr0115 spr0116 spr0116 spr0116 124191 124373 + hypothetical protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=spr0116 spr0117 spr0117 spr0117 124392 125294 + hypothetical protein gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=spr0117 spr0118 spr0118 spr0118 125317 125703 + hypothetical protein gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=spr0118 spr0119 spr0119 spr0119 125670 126428 + hypothetical protein gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=spr0119 spr0119a spr0119a spr0119a 126907 127104 + hypothetical protein gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=spr0119a spr0120 spr0120 spr0120 127503 127802 + hypothetical protein gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=spr0120 spr0121 spr0121 pspA pspA 128356 130215 + surface protein pspA gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=spr0121 spr0122 spr0122 mnmA mnmA 130562 131737 + tRNA-specific 2-thiouridylase MnmA catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene122 http://www.ncbi.nlm.nih.gov/gene/?term=spr0122 spr0123 spr0123 spr0123 131851 132333 + MutT/nudix family protein Similar to MutT protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=spr0123 spr0124 spr0124 gidA gidA 132343 134256 + tRNA uridine 5-carboxymethylaminomethyl modification protein GidA GidA%3B glucose-inhibited cell division protein A%3B involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=spr0124 spr0125 spr0125 spr0125 134636 136468 - hypothetical protein Predicted hydrolase of the metallo-beta-lactamase superfamily gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=spr0125 spr0126 spr0126 spr0126 136317 136550 - hypothetical protein gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=spr0126 spr0127 spr0127 orf51 orf51 137368 137520 - hypothetical protein Induced during competence gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=spr0127 spr0128 spr0128 spr0128 137522 137707 - hypothetical protein gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=spr0128 spr0129 spr0129 spr0129 137885 138568 + hypothetical protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=spr0129 spr0130 spr0130 rimI rimI 138565 139002 + ribosomal protein alanine acetyltransferase gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=spr0130 spr0131 spr0131 gcp gcp 138992 140002 + DNA-binding/iron metalloprotein/AP endonuclease in most organisms%2C only the N-terminal domain is present in a single polypeptide%3B in some archaea this domain is fused to a kinase domain%3B this gene is essential for growth in Escherichia coli and Bacillus subtilis%3B the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins%3B the Pyrococcus structure shows DNA-binding properties%2C iron-binding%2C ATP-binding%2C and AP endonuclease activity gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=spr0131 spr0132 spr0132 IS1167-truncation IS1167-truncation 140042 140853 - gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=spr0132 spr0135 spr0135 epsG epsG 142595 143809 + exopolysaccharide (EPS) synthesis glycosyltransferase gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=spr0135 spr0136 spr0136 glycosyltransferase glycosyltransferase 143802 144755 + glycosyl transferase gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=spr0136 spr0137 spr0137 ABC-NP ABC-NP 144765 146381 + ABC transporter ATP-binding protein gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=spr0137 spr0138 spr0138 spr0138 147164 147919 + hypothetical protein gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=spr0138 spr0139 spr0139 ugd ugd 147932 149104 + UDP-glucose dehydrogenase gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=spr0139 spr0140 spr0140 mutR mutR 149499 150362 + transcriptional regulator gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=spr0140 spr0141 spr0141 spr0141 150653 150886 + hypothetical protein gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=spr0141 spr0142 spr0142 spr0142 150908 151585 + hypothetical protein gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=spr0142 spr0143 spr0143 spr0143 151597 152262 + hypothetical protein gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=spr0143 spr0144 spr0144 spr0144 152331 153560 + hypothetical protein gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=spr0144 spr0146 spr0146 ABC-SBP ABC-SBP 154470 155300 + amino acid ABC transporter substrate-binding protein gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=spr0146 spr0147 spr0147 ABC-SBP ABC-SBP 155454 156308 + lipoprotein gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=spr0147 spr0148 spr0148 dapE dapE 156408 157781 + hypothetical protein gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=spr0148 spr0149 spr0149 ABC-NBD ABC-NBD 157774 158835 + ABC transporter ATP-binding protein gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=spr0149 spr0150 spr0150 ABC-MSD ABC-MSD 158837 159529 + ABC transporter permease gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=spr0150 spr0151 spr0151 spr0151 159559 160128 - hypothetical protein gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=spr0151 spr0152 spr0152 spr0152 160263 160877 + hypothetical protein gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=spr0152 spr0153 spr0153 hk07 hk07 160855 162525 + histidine kinase gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=spr0153 spr0154 spr0154 rr07 rr07 162537 163823 + DNA-binding response regulator gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=spr0154 spr0155 spr0155 spr0155 163827 164408 + hypothetical protein gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=spr0155 spr0156 spr0156 spr0156 164486 164956 + flavoprotein NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF gene gene153 http://www.ncbi.nlm.nih.gov/gene/?term=spr0156 spr0157 spr0157 spr0157 165249 166511 - hypothetical protein gene gene154 http://www.ncbi.nlm.nih.gov/gene/?term=spr0157 spr0158 spr0158 spr0158 166821 167279 - hypothetical protein gene gene155 http://www.ncbi.nlm.nih.gov/gene/?term=spr0158 spr0159 spr0159 spr0159 167276 167797 - hypothetical protein Similar to autolysin response regulator in Bacillus subtilis gene gene156 http://www.ncbi.nlm.nih.gov/gene/?term=spr0159 spr0160 spr0160 mutL mutL 168072 170021 + DNA mismatch repair protein This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex gene gene157 http://www.ncbi.nlm.nih.gov/gene/?term=spr0160 spr0161 spr0161 ribH ribH 170346 170813 - 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene158 http://www.ncbi.nlm.nih.gov/gene/?term=spr0161 spr0162 spr0162 ribA ribA 170814 172019 - 3%2C4-dihydroxy-2-butanone 4-phosphate synthase gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=spr0162 spr0163 spr0163 ribC ribC 172039 172674 - riboflavin synthase subunit alpha catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=spr0163 spr0164 spr0164 ribD ribD 172659 173759 - riboflavin biosynthesis protein RibD gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=spr0164 spr0165 spr0165 ruvA ruvA 174163 174756 + Holliday junction DNA helicase RuvA plays an essential role in ATP-dependent branch migration of the Holliday junction gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=spr0165 spr0166 spr0166 tag tag 174766 175329 + DNA-3-methyladenine glycosylase I gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=spr0166 spr0167 spr0167 spr0167 175326 176003 + hypothetical protein gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=spr0167 spr0168 spr0168 spr0168 176158 177189 - MccC family protein MccF-like proteins gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=spr0168 spr0169 spr0169 spr0169 177444 178148 - hypothetical protein gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=spr0169 spr0170 spr0170 corA corA 178139 179083 - magnesium/cobalt transporter CorA gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=spr0170 spr0171 spr0171 uvrA uvrA 179215 182046 + excinuclease ABC subunit A The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB%2C the uvrA molecules dissociate gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=spr0171 spr0172 spr0172 pepP pepP 182039 183100 + peptidase M24 family protein gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=spr0172 spr0173 spr0173 spxA spxA 183232 183630 + transcriptional regulator Spx the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters%3B in Bacillus subtilis this protein is a substrate for ClpXP protease%3B blocks transcription of the competence regulatory gene encoded by the srf operon%3B regulates a number of genes involved in thiol homeostasis including trxA and trxB%3B monomeric member of ArsC family of proteins%3B does not bind DNA%3B contains a disulfide bond between C10 and C13 which may sense disulfide stress gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=spr0173 spr0174 spr0174 spr0174 183696 184265 + hypothetical protein gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=spr0174 spr0175 spr0175 spr0175 184352 184618 + hypothetical protein gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=spr0175 spr0176 spr0176 spr0176 184622 185041 + Holliday junction resolvase-like protein similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=spr0176 spr0177 spr0177 spr0177 185057 185362 + hypothetical protein gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=spr0177 spr0178 spr0178 folC folC 185813 187069 + dihydrofolate:folylpolyglutamate synthetase gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=spr0178 spr0179 spr0179 spr0179 187066 187584 + hypothetical protein gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=spr0179 spr0180 spr0180 cls cls 187730 189262 + cardiolipin synthetase gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=spr0180 spr0181 spr0181 orf47 orf47 189340 189483 + hypothetical protein Induced during competence gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=spr0181 spr0182 spr0182 spr0182 189502 191058 + competence-induced protein Ccs4 Competence-induced protein Ccs4 gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=spr0182 spr0183 spr0183 nrdD nrdD 191172 193385 + anaerobic ribonucleoside triphosphate reductase Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=spr0183 spr0184 spr0184 spr0184 193581 194087 + hypothetical protein Similar to histone acetyltransferase HPA2 and related acetyltransferases gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=spr0184 spr0185 spr0185 nrdG nrdG 194080 194670 + anaerobic ribonucleoside-triphosphate reductase activating protein gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=spr0185 spr0186 spr0186 spr0186 194667 195284 + hypothetical protein gene gene183 http://www.ncbi.nlm.nih.gov/gene/?term=spr0186 spr0187 spr0187 rpsJ rpsJ 195551 195859 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene184 http://www.ncbi.nlm.nih.gov/gene/?term=spr0187 spr0188 spr0188 rplC rplC 196076 196702 + 50S ribosomal protein L3 binds directly near the 3' end of the 23S rRNA%2C where it nucleates assembly of the 50S subunit%3B essential for peptidyltransferase activity%3B mutations in this gene confer resistance to tiamulin gene gene185 http://www.ncbi.nlm.nih.gov/gene/?term=spr0188 spr0189 spr0189 rplD rplD 196727 197350 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene186 http://www.ncbi.nlm.nih.gov/gene/?term=spr0189 spr0190 spr0190 rplW rplW 197350 197646 + 50S ribosomal protein L23 binds third domain of 23S rRNA and protein L29%3B part of exit tunnel gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=spr0190 spr0191 spr0191 rplB rplB 197664 198497 + 50S ribosomal protein L2 one of the primary rRNA-binding proteins%3B required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=spr0191 spr0192 spr0192 rpsS rpsS 198601 198882 + 30S ribosomal protein S19 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=spr0192 spr0194 spr0194 rplV rplV 198894 199238 + 50S ribosomal protein L22 binds specifically to 23S rRNA during the early stages of 50S assembly%3B makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome%3B mutations in this gene result in erythromycin resistance%3B located near peptidyl-transferase center gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=spr0194 spr0195 spr0195 rpsC rpsC 199251 199904 + 30S ribosomal protein S3 forms a complex with S10 and S14%3B binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=spr0195 spr0196 spr0196 rplP rplP 199908 200321 + 50S ribosomal protein L16 located in the peptidyl transferase center and may be involved in peptidyl transferase activity%3B similar to archaeal L10e gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=spr0196 spr0197 spr0197 rpmC rpmC 200331 200537 + 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=spr0197 spr0198 spr0198 rpsQ rpsQ 200562 200822 + 30S ribosomal protein S17 primary binding protein%3B helps mediate assembly%3B involved in translation fidelity gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=spr0198 spr0199 spr0199 rplN rplN 200848 201216 + 50S ribosomal protein L14 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=spr0199 spr0200 spr0200 rplX rplX 201294 201599 + 50S ribosomal protein L24 assembly initiator protein%3B binds to 5' end of 23S rRNA and nucleates assembly of the 50S%3B surrounds polypeptide exit tunnel gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=spr0200 spr0201 spr0201 rplE rplE 201623 202165 + 50S ribosomal protein L5 part of 50S and 5S/L5/L18/L25 subcomplex%3B contacts 5S rRNA and P site tRNA%3B forms a bridge to the 30S subunit in the ribosome by binding to S13 gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=spr0201 spr0202 spr0202 rpsN rpsN 202183 202452 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=spr0202 spr0203 spr0203 rpsH rpsH 202737 203135 + 30S ribosomal protein S8 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=spr0203 spr0204 spr0204 rplF rplF 203327 203863 + 50S ribosomal protein L6 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein%3B RNA-binding appears to be in the C-terminal domain%3B mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain%3B it has been localized to a region between the base of the L7/L12 stalk and the central protuberance gene gene200 http://www.ncbi.nlm.nih.gov/gene/?term=spr0204 spr0205 spr0205 rplR rplR 203947 204303 + 50S ribosomal protein L18 binds 5S rRNA along with protein L5 and L25 gene gene201 http://www.ncbi.nlm.nih.gov/gene/?term=spr0205 spr0206 spr0206 rpsE rpsE 204321 204815 + 30S ribosomal protein S5 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body%3B contacts S4 and S8%3B with S4 and S12 plays a role in translational accuracy%3B mutations in this gene result in spectinomycin resistance gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=spr0206 spr0207 spr0207 rpmD rpmD 204829 205011 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=spr0207 spr0208 spr0208 rplO rplO 205156 205596 + 50S ribosomal protein L15 late assembly protein gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=spr0208 spr0209 spr0209 secY secY 205609 206919 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=spr0209 spr0210 spr0210 adk adk 207070 207708 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=spr0210 spr0211 spr0211 infA infA 207825 208043 + translation initiation factor IF-1 stimulates the activities of the other two initiation factors%2C IF-2 and IF-3 gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=spr0211 spr0212 spr0212 rpmJ rpmJ 208068 208184 + 50S ribosomal protein L36 smallest protein in the large subunit%3B similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc%3B the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion%3B the proteins in this group have the motif gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=spr0212 spr0213 spr0213 rpsM rpsM 208202 208567 + 30S ribosomal protein S13 located at the top of the head of the 30S subunit%2C it contacts several helices of the 16S rRNA%3B makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5%3B contacts P-site tRNA gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=spr0213 spr0214 spr0214 rpsK rpsK 208585 208968 + 30S ribosomal protein S11 located on the platform of the 30S subunit%2C it bridges several disparate RNA helices of the 16S rRNA%3B forms part of the Shine-Dalgarno cleft in the 70S ribosome%3B interacts with S7 and S18 and IF-3 gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=spr0214 spr0215 spr0215 rpoA rpoA 209011 209946 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=spr0215 spr0216 spr0216 rplQ rplQ 209958 210344 + 50S ribosomal protein L17 is a component of the macrolide binding site in the peptidyl transferase center gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=spr0216 spr0217 spr0217 spr0217 210609 210875 + hypothetical protein ACT domain-containing protein gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=spr0217 spr0218 spr0218 spr0218 210885 212222 + hypothetical protein gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=spr0218 spr0219 spr0219 gpmB gpmB 212409 213158 + phosphoglycerate mutase gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=spr0219 spr0220 spr0220 ABC-MSP ABC-MSP 213261 214295 - iron ABC transporter permease gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=spr0220 spr0221 spr0221 ABC-MSP ABC-MSP 214280 214906 - iron ABC transporter permease gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=spr0221 spr0222 spr0222 ABC-NBD ABC-NBD 214896 215987 - ABC transporter ATP-binding protein gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=spr0222 spr0223 spr0223 ABC-SBP-truncation ABC-SBP-truncation 216000 216707 - gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=spr0223 spr0225 spr0225 spr0225 217339 217536 - hypothetical protein gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=spr0225 spr0226 spr0226 pflE pflE 217611 218387 - pyruvate formate-lyase 3 gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=spr0226 spr0227 spr0227 deoR deoR 218461 219255 + DEOR-type transcriptional regulator gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=spr0227 spr0228 spr0228 spr0228 219268 220248 + hypothetical protein Resembles sorbitol operon regulator gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=spr0228 spr0229 spr0229 PTS-EIIA PTS-EIIA 220443 220763 + PTS system transporter subunit IIA gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=spr0229 spr0230 spr0230 PTS-EIIB PTS-EIIB 220809 221117 + PTS system transporter subunit IIB gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=spr0230 spr0231 spr0231 PTS-EIIC PTS-EIIC 221110 222432 + PTS system transporter subunit IIC gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=spr0231 spr0232 spr0232 pflF pflF 222574 225021 + formate acetyltransferase 3 gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=spr0232 spr0233 spr0233 talC talC 225040 225708 + fructose-6-phosphate aldolase similar to transaldolase from Escherichia coli%3B many organisms have multiple copies gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=spr0233 spr0234 spr0234 gldA gldA 225726 226814 + glycerol dehydrogenase forms dimers and octamers%3B involved in conversion of glycerol to dihydroxy-acetone gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=spr0234 spr0235 spr0235 leuS leuS 227269 229770 + leucyl-tRNA synthetase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=spr0235 spr0236 spr0236 spr0236 229964 230659 + hypothetical protein Similar to acetyltransferases%2C including N-acetylases of ribosomal proteins gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=spr0236 spr0237 spr0237 spr0237 230671 231087 + hypothetical protein Similar to histone acetyltransferase HPA2 and related acetyltransferases gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=spr0237 spr0238 spr0238 ruvB ruvB 232128 233126 + Holliday junction DNA helicase RuvB promotes strand exchange during homologous recombination%3B RuvAB complex promotes branch migration%3B RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences%3B forms hexameric rings around opposite DNA arms%3B requires ATP for branch migration and orientation of RuvAB complex determines direction of migration gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=spr0238 spr0239 spr0239 spr0239 233107 233679 + hypothetical protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=spr0239 spr0240 spr0240 uppS uppS 233892 234668 + undecaprenyl pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=spr0240 spr0241 spr0241 cdsA cdsA 234677 235480 + phosphatidate cytidylyltransferase gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=spr0241 spr0242 spr0242 eep eep 235502 236761 + determinant for enhanced expression of pheromone gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=spr0242 spr0243 spr0243 proS proS 236774 238627 + prolyl-tRNA synthetase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene238 http://www.ncbi.nlm.nih.gov/gene/?term=spr0243 spr0244 spr0244 bglA bglA 238727 240106 + 6-phospho-beta-glucosidase gene gene239 http://www.ncbi.nlm.nih.gov/gene/?term=spr0244 spr0245 spr0245 glmS glmS 240298 242106 + glucosamine--fructose-6-phosphate aminotransferase Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene240 http://www.ncbi.nlm.nih.gov/gene/?term=spr0245 spr0246 spr0246 spr0246 242225 243274 + hypothetical protein Similar to coenzyme F420-dependent N5%2CN10-methylene tetrahydromethanopterin reductase and and related flavin-dependent oxidoreductases gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=spr0246 spr0247 spr0247 pulA pulA 243374 247144 - alkaline amylopullulanase gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=spr0247 spr0248 spr0248 rpsL rpsL 247561 247974 + 30S ribosomal protein S12 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone%3B located at the interface of the 30S and 50S subunits%2C it traverses the body of the 30S subunit contacting proteins on the other side%3B mutations in the S12 gene confer streptomycin resistance gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=spr0248 spr0249 spr0249 rpsG rpsG 247994 248464 + 30S ribosomal protein S7 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=spr0249 spr0250 spr0250 fusA fusA 248889 250970 + elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=spr0250 spr0251 spr0251 polC polC 251074 255465 + DNA polymerase III PolC catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B required for leading strand synthesis%3B PolC exhibits 3' to 5' exonuclease activity gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=spr0251 spr0252 spr0252 spr0252 255567 255830 + hypothetical protein gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=spr0252 spr0253 spr0253 spr0253 255823 256101 + hypothetical protein gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=spr0253 spr0253a spr0253a spr0253a 256122 256274 + hypothetical protein gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=spr0253a spr0254 spr0254 pepS pepS 256296 257537 + aminopeptidase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=spr0254 spr0255 spr0255 spr0255 257547 257777 + hypothetical protein gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=spr0255 spr0256 spr0256 rsuA rsuA 258090 258812 + ribosomal small subunit pseudouridine synthase A gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=spr0256 spr0257 spr0257 spr0257 258893 259057 + hypothetical protein gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=spr0257 spr0258 spr0258 pepC pepC 259029 260363 + aminopeptidase gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=spr0258 spr0259 spr0259 manN manN 260419 261330 - PTS system mannose-specific transporter subunit EIID gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=spr0259 spr0260 spr0260 manM manM 261354 262157 - PTS system mannose-specific transporter subunit IIC gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=spr0260 spr0261 spr0261 manL manL 262185 263183 - PTS system mannose-specific transporter subunit IIAB gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=spr0261 spr0262 spr0262 adhP adhP 263358 264377 - alcohol dehydrogenase similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=spr0262 spr0263 spr0263 spr0263 264716 265528 - Cof family protein gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=spr0263 spr0264 spr0264 spr0264 265664 267136 + xanthine/uracil permease gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=spr0264 spr0265 spr0265 spr0265 267187 267897 + hypothetical protein gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=spr0265 spr0266 spr0266 sulA sulA 268022 268966 + dihydropteroate synthase gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=spr0266 spr0267 spr0267 sulB sulB 268968 270290 + dihydrofolate synthetase gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=spr0267 spr0268 spr0268 folE folE 270271 270825 + GTP cyclohydrolase I involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=spr0268 spr0269 spr0269 sulD sulD 270868 271680 + bifunctional folate synthesis protein gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=spr0269 spr0270 spr0270 spr0270 271725 272096 - hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=spr0270 spr0271 spr0271 rplM rplM 272399 272845 + 50S ribosomal protein L13 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=spr0271 spr0272 spr0272 rpsI rpsI 272865 273257 + 30S ribosomal protein S9 forms a direct contact with the tRNA during translation gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=spr0272 spr0275 spr0275 spr0275 273944 274309 + hypothetical protein gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=spr0275 spr0276 spr0276 celA celA 274499 275935 + 6-phospho-beta-glucosidase converts 6-phospho-beta-D-glucosyl-(1%2C4)-D-glucose to glucose and glucose 6-phosphate%3B required for cellobiose uptake and metabolism gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=spr0276 spr0277 spr0277 spr0277 275987 276226 + hypothetical protein gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=spr0277 spr0278 spr0278 celB celB 276356 276670 + PTS system cellobiose transporter subunit IIB required for cellobiose uptake and metabolism gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=spr0278 spr0279 spr0279 bglG bglG 276788 278767 + BigG family transcription antiterminator gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=spr0279 spr0280 spr0280 celC celC 278777 279091 + PTS system cellobiose transporter subunit IIA required for cellobiose uptake and metabolism gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=spr0280 spr0281 spr0281 spr0281 279110 279616 + hypothetical protein gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=spr0281 spr0282 spr0282 celD celD 279696 281042 + PTS system cellobiose transporter subunit IIC required for cellobiose uptake and metabolism gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=spr0282 spr0283 spr0283 spr0283 281424 281600 + hypothetical protein gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=spr0283 spr0284 spr0284 xylS xylS 282002 284215 + Alpha-xylosidase gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=spr0284 spr0285 spr0285 basA basA 284437 284913 - glutathione peroxidase gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=spr0285 spr0286 spr0286 hysA hysA 285103 288339 + hyaluronate lyase gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=spr0286 spr0287 spr0287 kdgA kdgA 289483 290112 - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate%3B or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate gene gene281 http://www.ncbi.nlm.nih.gov/gene/?term=spr0287 spr0288 spr0288 kdgK kdgK 290122 291123 - 2-keto-3-deoxygluconate kinase gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=spr0288 spr0289 spr0289 spr0289 291154 291795 - hypothetical protein gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=spr0289 spr0290 spr0290 gno gno 291814 292629 - gluconate 5-dehydrogenase Involved in the nonphosphorylative%2C ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=spr0290 spr0291 spr0291 PTS-EII PTS-EII 292900 293334 + PTS system transporter subunit IIA gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=spr0291 spr0292 spr0292 ugl ugl 293346 294536 + glucuronyl hydrolase gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=spr0292 spr0293 spr0293 PTS-EII PTS-EII 294547 295038 + PTS system transporter subunit IIB gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=spr0293 spr0294 spr0294 PTS-EII PTS-EII 295053 295832 + PTS system transporter subunit IIC gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=spr0294 spr0295 spr0295 PTS-EII PTS-EII 295819 296637 + PTS system transporter subunit IID gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=spr0295 spr0296 spr0296 spr0296 296637 296930 + preprotein translocase%2C YajC subunit gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=spr0296 spr0297 spr0297 spr0297 296952 298853 + hypothetical protein gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=spr0297 spr0298 spr0298 regR regR 298847 299914 + GalR family transcription regulator gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=spr0298 spr0300 spr0300 spr0300 300360 300602 - hypothetical protein gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=spr0300 spr0301 spr0301 yorfE yorfE 300618 300812 - transcriptional regulator gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=spr0301 spr0302 spr0302 mraW mraW 300978 301928 + S-adenosyl-methyltransferase MraW gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=spr0302 spr0303 spr0303 ftsL ftsL 301940 302257 + cell division protein FtsL gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=spr0303 spr0304 spr0304 pbpX pbpX 302261 304513 + penicillin-binding protein 2X gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=spr0304 spr0305 spr0305 mraY mraY 304515 305495 + phospho-N-acetylmuramoyl-pentapeptide-transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=spr0305 spr0307 spr0307 clpL clpL 306052 308157 + ATP-dependent protease ATP-binding subunit gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=spr0307 spr0308 spr0308 luxS luxS 308453 308935 - S-ribosylhomocysteinase catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=spr0308 spr0309 spr0309 spr0309 309030 310514 - hypothetical protein gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=spr0309 spr0310 spr0310 dexB dexB 310667 312274 + glucan 1%2C6-alpha-glucosidase gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=spr0310 spr0311 spr0311 spr0311 312433 312606 + hypothetical protein gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=spr0311 spr0312 spr0312 spr0312 313115 313462 - transposase B gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=spr0312 spr0314 spr0314 cps2A cps2A 313695 314657 + hypothetical protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=spr0314 spr0315 spr0315 cps2H cps2H 314551 315585 + hypothetical protein gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=spr0315 spr0316 spr0316 cps2I cps2I 315715 316872 + hypothetical protein gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=spr0316 spr0317 spr0317 cps2J cps2J 316869 318278 + hypothetical protein gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=spr0317 spr0318 spr0318 cps2K cps2K 318314 319552 + hypothetical protein gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=spr0318 spr0319 spr0319 cps2P cps2P 319581 320186 + hypothetical protein gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=spr0319 spr0320 spr0320 cps2L cps2L 320264 321133 + hypothetical protein gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=spr0320 spr0321 spr0321 cps2M cps2M 321134 321727 + hypothetical protein gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=spr0321 spr0322 spr0322 cpsN cpsN 321740 322789 + dTDP-glucose-4%2C6-dehydratase gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=spr0322 spr0323 spr0323 cpsO cpsO 322855 323706 + dTDP-L-rhamnose synthase gene gene314 http://www.ncbi.nlm.nih.gov/gene/?term=spr0323 spr0325 spr0325 spr0325 324231 324680 + hypothetical protein gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=spr0325 spr0326 spr0326 spr0326 324751 324909 + hypothetical protein gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=spr0326 spr0327 spr0327 aliA aliA 325111 327093 + oligopeptide ABC transporter substrate-binding protein gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=spr0327 spr0328 spr0328 spr0328 327393 332696 + cell wall surface anchor family protein gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=spr0328 spr0329 spr0329 pbpA pbpA 332863 335022 - penicillin-binding protein 1A gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=spr0329 spr0330 spr0330 recU recU 335019 335615 - Holliday junction-specific endonuclease functions in homologous recombination%2C DNA repair%2C and chromosome segregation%3B binds preferentially to three- and four-stranded DNA intermediates%3B introduces specific nick sites in four-stranded DNA substrates%3B functions similarly to Escherichia coli RuvC gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=spr0330 spr0331 spr0331 spr0331 335681 336208 + hypothetical protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=spr0331 spr0332 spr0332 spr0332 336266 336607 + hypothetical protein gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=spr0332 spr0333 spr0333 spr0333 337078 338250 + hypothetical protein gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=spr0333 spr0334 spr0334 spr0334 338263 339657 + hypothetical protein gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=spr0334 spr0335 spr0335 gnd gnd 339733 341157 + 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=spr0335 spr0336 spr0336 csrR csrR 341169 341858 + DNA-binding response regulator gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=spr0336 spr0337 spr0337 cbpF cbpF 341956 342972 + choline-binding protein F gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=spr0337 spr0338 spr0338 mvk mvk 343094 343972 + mevalonate kinase gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=spr0338 spr0339 spr0339 mvd1 mvd1 343873 344907 + diphosphomevalonate decarboxylase gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=spr0339 spr0340 spr0340 mvaK2 mvaK2 344894 345901 + phosphomevalonate kinase gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=spr0340 spr0341 spr0341 fni fni 345885 346895 + isopentenyl pyrophosphate isomerase catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=spr0341 spr0342 spr0342 spr0342 346973 347671 + hypothetical protein gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=spr0342 spr0343 spr0343 hk03 hk03 347668 348663 + sensor histidine kinase gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=spr0343 spr0344 spr0344 rr03 rr03 348677 349309 + DNA-binding response regulator gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=spr0344 spr0349 spr0349 cbpG-truncation cbpG-truncation 350465 351374 + gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=spr0349 spr0351 spr0351 pcpC pcpC 351393 352277 + choline-binding protein gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=spr0351 spr0352 spr0352 IS861-truncation IS861-truncation 352538 353113 - gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=spr0352 spr0352a spr0352a spr0352a 353339 353608 - DNA-binding protein gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=spr0352a spr0356 spr0356 mtlA mtlA 353760 355529 + PTS system mannitol-specific transporter subunit IIBC gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=spr0356 spr0357 spr0357 spr0357 355553 357508 + transcriptional regulator transcriptional regulator gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=spr0357 spr0358 spr0358 mtlF mtlF 357510 357947 + PTS system mannitol-specific transporter subunit IIA gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=spr0358 spr0359 spr0359 mtlD mtlD 358009 359145 + mannitol-1-phosphate 5-dehydrogenase gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=spr0359 spr0362 spr0362 tig tig 359944 361227 + trigger factor Tig%3B RopA%3B peptidyl-prolyl cis/trans isomerase%3B promotes folding of newly synthesized proteins%3B binds ribosomal 50S subunit%3B forms a homodimer gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=spr0362 spr0363 spr0363 recD recD 361275 363641 - exonuclease V gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=spr0363 spr0364 spr0364 spi spi 363875 364489 - signal peptidase I gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=spr0364 spr0365 spr0365 rnhB rnhB 364501 365373 - ribonuclease HIII An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=spr0365 spr0366 spr0366 spr0366 365451 365762 + hypothetical protein gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=spr0366 spr0367 spr0367 spr0367 365759 366307 + hypothetical protein gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=spr0367 spr0368 spr0368 mutS2 mutS2 366411 368747 + MutS2 family protein gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=spr0368 spr0369 spr0369 dagA dagA 369089 370411 + sodium:alanine symporter family protein gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=spr0369 spr0370 spr0370 mip mip 370629 371177 + hypothetical protein gene gene352 http://www.ncbi.nlm.nih.gov/gene/?term=spr0370 spr0371 spr0371 shetA shetA 371275 372186 + exfoliative toxin gene gene353 http://www.ncbi.nlm.nih.gov/gene/?term=spr0371 spr0372 spr0372 serS serS 372211 373485 - seryl-tRNA synthetase catalyzes a two-step reaction%2C first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene354 http://www.ncbi.nlm.nih.gov/gene/?term=spr0372 spr0373 spr0373 spr0373 373698 374069 - hypothetical protein gene gene355 http://www.ncbi.nlm.nih.gov/gene/?term=spr0373 spr0374 spr0374 lysC lysC 374072 375436 - aspartate kinase catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B lysine and threonine sensitive gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=spr0374 spr0375 spr0375 phaB phaB 375761 376546 + enoyl-CoA hydratase Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=spr0375 spr0376 spr0376 spr0376 376640 377074 + hypothetical protein Probable transcriptional regulator gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=spr0376 spr0377 spr0377 fabH fabH 377074 378048 + 3-oxoacyl-ACP synthase FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=spr0377 spr0378 spr0378 acpP acpP 378108 378332 + acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=spr0378 spr0379 spr0379 fabK fabK 378451 379425 + enoyl-acyl carrier protein(ACP) reductase gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=spr0379 spr0380 spr0380 fabD fabD 379418 380338 + ACP S-malonyltransferase gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=spr0380 spr0381 spr0381 fabG fabG 380372 381103 + 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=spr0381 spr0382 spr0382 fabF fabF 381116 382360 + 3-oxoacyl-ACP synthase FabF%3B beta-ketoacyl-ACP synthase II%2C KASII%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=spr0382 spr0383 spr0383 accB accB 382363 382848 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex%2C the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=spr0383 spr0384 spr0384 fabZ fabZ 382845 383267 + (3R)-hydroxymyristoyl-ACP dehydratase in Pseudomonas aeruginosa this enzyme is a trimer of dimers%3B essential for membrane formation%3B performs third step of type II fatty acid biosynthesis%3B catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=spr0384 spr0385 spr0385 accC accC 383279 384646 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=spr0385 spr0386 spr0386 accD accD 384683 385549 + acetyl-CoA carboxylase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=spr0386 spr0387 spr0387 accA accA 385546 386313 + acetyl-CoA carboxylase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein%3B these proteins present a shorter N-terminus gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=spr0387 spr0388 spr0388 spr0388 386472 386657 + hypothetical protein gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=spr0388 spr0390 spr0390 nusB nusB 387424 387864 - transcription antitermination protein NusB Regulates rRNA biosynthesis by transcriptional antitermination gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=spr0390 spr0391 spr0391 spr0391 387839 388228 - hypothetical protein gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=spr0391 spr0392 spr0392 efp efp 388250 388810 - elongation factor P Involved in peptide bond synthesis%3B alters the affinity of the ribosome for aminoacyl-tRNA gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=spr0392 spr0393 spr0393 gatB gatB 388939 390381 - aspartyl/glutamyl-tRNA amidotransferase subunit B allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases%3B reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=spr0393 spr0394 spr0394 gatA gatA 390381 391847 - aspartyl/glutamyl-tRNA amidotransferase subunit A allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases%3B reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=spr0394 spr0395 spr0395 gatC gatC 391847 392149 - aspartyl/glutamyl-tRNA amidotransferase subunit C allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases%3B reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA%3B some Mycoplasma proteins contain an N-terminal fusion to an unknown domain gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=spr0395 spr0396 spr0396 prfC prfC 392362 393906 + peptide chain release factor 3 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred%3B GDP/GTP-binding protein gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=spr0396 spr0397 spr0397 spr0397 394175 394660 + hypothetical protein gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=spr0397 spr0398 spr0398 rpmB rpmB 394776 394964 + 50S ribosomal protein L28 required for 70S ribosome assembly gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=spr0398 spr0399 spr0399 asp23 asp23 395121 395486 + hypothetical protein gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=spr0399 spr0400 spr0400 spr0400 395489 397156 + hypothetical protein gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=spr0400 spr0401 spr0401 ilvB ilvB 397357 399057 + acetolactate synthase catalytic subunit catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=spr0401 spr0402 spr0402 ilvH ilvH 399026 399526 + acetolactate synthase 3 regulatory subunit with IlvI catalyzes the formation of 2-acetolactate from pyruvate%2C the small subunit is required for full activity and valine sensitivity%3B E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates%2C valine sensitivity and affinity for cofactors%3B also known as acetolactate synthase 3 small subunit gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=spr0402 spr0403 spr0403 ilvC ilvC 399592 400614 + ketol-acid reductoisomerase catalyzes the formation of (R)-2%2C3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=spr0403 spr0404 spr0404 spr0404 400691 401181 + gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=spr0404 spr0405 spr0405 spr0405 401195 401551 + hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=spr0405 spr0406 spr0406 ilvA ilvA 401601 402851 + threonine dehydratase catalyzes the formation of 2-oxobutanoate from L-threonine%3B biosynthetic gene gene387 http://www.ncbi.nlm.nih.gov/gene/?term=spr0406 spr0407 spr0407 spr0407 403586 403801 + hypothetical protein gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=spr0407 spr0408 spr0408 glnQ glnQ 403910 404650 - amino acid ABC transporter ATP-binding protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=spr0408 spr0409 spr0409 glnH glnH 404650 406215 - glutamine ABC transporter substrate-binding protein gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=spr0409 spr0410 spr0410 spr0410 406350 408242 + hypothetical protein gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=spr0410 spr0412 spr0412 transposase_F transposase_F 408542 409410 - gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=spr0412 spr0413 spr0413 uppP uppP 409666 410511 + undecaprenyl pyrophosphate phosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=spr0413 spr0414 spr0414 dinP dinP 410657 411727 - DNA polymerase IV involved in translesion DNA polymerization with beta clamp of polymerase III%3B belongs to Y family of polymerases%3B does not contain proofreading function gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=spr0414 spr0415 spr0415 pfl pfl 412113 414437 + formate acetyltransferase gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=spr0415 spr0417 spr0417 spr0417 415349 415633 - hypothetical protein gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=spr0417 spr0420 spr0420 xylR xylR 417068 418291 - ROK family protein gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=spr0420 spr0421 spr0421 PTS-EII PTS-EII 418456 419781 + PTS system cellobiose-specific transporter subunit IIC gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=spr0421 spr0422 spr0422 spr0422 419729 421669 + hypothetical protein gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=spr0422 spr0423 spr0423 PTS-EII PTS-EII 421837 422181 + PTS system lactose-specific transporter subunit IIA gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=spr0423 spr0424 spr0424 lacG lacG 422191 423603 + 6-phospho-beta-galactosidase catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=spr0424 spr0425 spr0425 PTS-EII PTS-EII 423672 425351 + PTS system sugar-specific transporter subunit EII gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=spr0425 spr0426 spr0426 trkH trkH 425479 426918 - Trk transporter membrane-spanning protein gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=spr0426 spr0427 spr0427 trkA trkA 426922 428271 - potassium transporter peripheral membrane component involved in potassium uptake%3B found to be peripherally associated with the inner membrane in Escherichia coli%3B contains an NAD-binding domain gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=spr0427 spr0428 spr0428 spr0428 428433 429308 + hypothetical protein gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=spr0428 spr0429 spr0429 spr0429 429323 429871 + hypothetical protein gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=spr0429 spr0429a spr0429a spr0429a 429878 430090 + hypothetical protein gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=spr0429a spr0430 spr0430 ABC-NBD ABC-NBD 430192 431874 + ABC transporter ATP-binding protein gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=spr0430 spr0431 spr0431 ABC-MSD ABC-MSD 431859 432689 + hypothetical protein gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=spr0431 spr0432 spr0432 cspR cspR 432843 433385 + rRNA methylase gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=spr0432 spr0433 spr0433 spr0433 433829 434407 + hypothetical protein gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=spr0433 spr0434 spr0434 spr0434 434397 435047 + PAP2 family protein Probable phosphatidic acid phosphatase gene gene412 http://www.ncbi.nlm.nih.gov/gene/?term=spr0434 spr0435 spr0435 spr0435 435075 435464 + hypothetical protein gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=spr0435 spr0436 spr0436 spr0436 435469 435918 + hypothetical protein gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=spr0436 spr0437 spr0437 rpoE rpoE 436046 436633 + DNA-directed RNA polymerase subunit delta participates in both the initiation and recycling phases of transcription%3B in the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=spr0437 spr0438 spr0438 pyrG pyrG 437023 438630 + CTP synthetase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=spr0438 spr0439 spr0439 spr0439 439189 440820 - hypothetical protein Probable integral membrane protein gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=spr0439 spr0440 spr0440 spr0440 441113 446092 + endo-beta-N-acetylglucosaminidase Similar to endo-beta-N-acetylglucosaminidase gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=spr0440 spr0441 spr0441 pgk pgk 446182 447378 + phosphoglycerate kinase Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway gene gene419 http://www.ncbi.nlm.nih.gov/gene/?term=spr0441 spr0442 spr0442 spr0442 447514 448041 + hypothetical protein gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=spr0442 spr0443 spr0443 glnR glnR 448118 448474 + transcriptional repressor of the glutamine synthetase gene gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=spr0443 spr0444 spr0444 glnA glnA 448511 449857 + glutamine synthetase%2C type I gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=spr0444 spr0445 spr0445 hsdS hsdS 450637 451917 + type I restriction-modification system S subunit gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=spr0445 spr0446 spr0446 hsdS hsdS 451871 452470 - type I restriction-modification system S subunit gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=spr0446 spr0447 spr0447 xerD xerD 452481 453278 - integrase/recombinase gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=spr0447 spr0448 spr0448 hsdS hsdS 453335 454903 - type I restriction-modification system S subunit gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=spr0448 spr0449 spr0449 hsdM hsdM 454903 456366 - type I restriction-modification system M subunit gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=spr0449 spr0450 spr0450 hsdR hsdR 456379 458712 - type I restriction-modification system R subunit gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=spr0450 spr0451 spr0451 spr0451 459085 459285 + hypothetical protein gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=spr0451 spr0452 spr0452 spr0452 459320 459829 + hypothetical protein gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=spr0452 spr0453 spr0453 hrcA hrcA 459960 461027 + heat-inducible transcription repressor Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=spr0453 spr0454 spr0454 grpE grpE 461030 461578 + heat shock protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=spr0454 spr0455 spr0455 dnaK dnaK 462058 463881 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=spr0455 spr0456 spr0456 dnaJ dnaJ 464641 465759 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=spr0456 spr0457 spr0457 spr0457 466094 466381 - hypothetical protein gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=spr0457 spr0458 spr0458 spr0458 466391 466801 - hypothetical protein HIT-like protein gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=spr0458 spr0459 spr0459 ABC-NBD ABC-NBD 466869 467600 + ABC transporter ATP-binding protein gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=spr0459 spr0460 spr0460 ABC-MSP ABC-MSP 467597 468646 + ABC transporter permease gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=spr0460 spr0461 spr0461 blpT blpT 468814 469143 - hypothetical protein gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=spr0461 spr0462 spr0462 blpS blpS 469419 469757 + regulatory protein BlpS gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=spr0462 spr0463 spr0463 rr13 rr13 469762 470499 + response regulator BlpR gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=spr0463 spr0464 spr0464 hk13 hk13 470513 471853 + histidine kinase gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=spr0464 spr0465 spr0465 ip ip 471895 472050 - peptide pheromone BlpC gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=spr0465 spr0466 spr0466 spr0466 472107 473468 - gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=spr0466 spr0468 spr0468 spr0468 473479 475636 - gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=spr0468 spr0470 spr0470 spr0470 475926 476159 + hypothetical protein gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=spr0470 spr0471 spr0471 spr0471 476175 476354 + hypothetical protein gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=spr0471 spr0472 spr0472 blpY blpY 476191 476880 + immunity protein BlpY gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=spr0472 spr0473 spr0473 blpZ blpZ 476922 477155 + hypothetical protein gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=spr0473 spr0474 spr0474 pncP pncP 477306 477917 + ABC transporter ATP-binding protein gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=spr0474 spr0475 spr0475 spr0475 478078 478872 + hypothetical protein gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=spr0475 spr0476 spr0476 trmB trmB 478869 479504 + tRNA (guanine-N(7)-)-methyltransferase tRNA (guanine-N(7)-)-methyltransferase%3B catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine gene gene452 http://www.ncbi.nlm.nih.gov/gene/?term=spr0476 spr0477 spr0477 spr0477 479630 480109 + hypothetical protein in Streptococcus pneumoniae this gene was found to be essential%3B structure determination of the Streptococcus protein shows that it is similar to a number of other proteins gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=spr0477 spr0478 spr0478 nusA nusA 480153 481289 + transcription elongation factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene454 http://www.ncbi.nlm.nih.gov/gene/?term=spr0478 spr0479 spr0479 spr0479 481311 481604 + hypothetical protein gene gene455 http://www.ncbi.nlm.nih.gov/gene/?term=spr0479 spr0480 spr0480 spr0480 481597 481896 + hypothetical protein Probable ribosomal protein gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=spr0480 spr0481 spr0481 infB infB 481913 484705 + translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=spr0481 spr0482 spr0482 rbfA rbfA 484929 485306 + ribosome-binding factor A associates with free 30S ribosomal subunits%3B essential for efficient processing of 16S rRNA%3B in Escherichia coli rbfA is induced by cold shock gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=spr0482 spr0483 spr0483 spr0483 485549 486364 + hypothetical protein gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=spr0483 spr0484 spr0484 spr0484 486366 486548 + hypothetical protein gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=spr0484 spr0485 spr0485 spr0485 486986 487231 + hypothetical protein gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=spr0485 spr0486 spr0486 spr0486 487231 488565 + hypothetical protein gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=spr0486 spr0487 spr0487 spr0487 488575 488829 + hypothetical protein gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=spr0487 spr0488 spr0488 spr0488 488925 489320 + hypothetical protein gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=spr0488 spr0489 spr0489 spr0489 489732 490181 + hypothetical protein gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=spr0489 spr0490 spr0490 spr0490 490168 490725 + hypothetical protein Probable acetyl transferase gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=spr0490 spr0491 spr0491 spr0491 490727 491689 + hypothetical protein gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=spr0491 spr0492 spr0492 valS valS 491701 494352 + valyl-tRNA synthetase valine--tRNA ligase%3B ValRS%3B converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val)%3B class-I aminoacyl-tRNA synthetase type 1 subfamily%3B has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=spr0492 spr0493 spr0493 spr0493 494407 495177 + hypothetical protein gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=spr0493 spr0494 spr0494 spr0494 495460 496263 + cell filamentation protein Fic-related protein gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=spr0494 spr0495 spr0495 IS861-truncation IS861-truncation 496379 497191 - gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=spr0495 spr0499 spr0499 spr0499 497816 498883 + hypothetical protein gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=spr0499 spr0499a spr0499a spr0499a 497417 497686 - hypothetical protein gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=spr0499a spr0500 spr0500 spr0500 498980 500571 + gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=spr0500 spr0504 spr0504 licT licT 500872 501711 + BglG family transcriptional antiterminator gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=spr0504 spr0505 spr0505 PTS-EII PTS-EII 501729 503567 + PTS system beta-glucosides-specific transporter subunit IIABC gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=spr0505 spr0506 spr0506 bglH bglH 503580 504995 + 6-phospho-beta-glucosidase gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=spr0506 spr0507 spr0507 pheS pheS 505587 506633 + phenylalanyl-tRNA synthetase subunit alpha catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a heterotetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 1 subfamily gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=spr0507 spr0508 spr0508 spr0508 506633 507142 + hypothetical protein Probable transcriptional regulator gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=spr0508 spr0509 spr0509 pheT pheT 507219 509621 + phenylalanyl-tRNA synthetase subunit beta catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a tetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 2 subfamily gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=spr0509 spr0510 spr0510 spr0510 509689 510690 - hypothetical protein gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=spr0510 spr0511 spr0511 IS1239-truncation IS1239-truncation 510846 511341 + gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=spr0511 spr0513 spr0513 spr0513 511419 511685 + hypothetical protein gene gene483 http://www.ncbi.nlm.nih.gov/gene/?term=spr0513 spr0514 spr0514 metE metE 511802 514195 + 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine gene gene484 http://www.ncbi.nlm.nih.gov/gene/?term=spr0514 spr0515 spr0515 metF metF 514259 515125 + 5%2C10-methylenetetrahydrofolate reductase gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=spr0515 spr0516 spr0516 pnpA pnpA 515696 518023 + polynucleotide phosphorylase gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=spr0516 spr0517 spr0517 cysE cysE 518039 518656 + serine acetyltransferase gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=spr0517 spr0518 spr0518 spr0518 518668 519552 + hypothetical protein gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=spr0518 spr0519 spr0519 cysS cysS 519634 520977 + cysteinyl-tRNA synthetase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=spr0519 spr0520 spr0520 spr0520 520970 521356 + hypothetical protein gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=spr0520 spr0521 spr0521 spr0521 521360 522244 + hypothetical protein Leucine rich protein gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=spr0521 spr0522 spr0522 spr0522 522381 522979 + gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=spr0522 spr0523 spr0523 transposase_H-truncation transposase_H-truncation 523125 523511 + gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=spr0523 spr0524 spr0524 vex1 vex1 523650 524927 + peptide ABC transporter permease gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=spr0524 spr0525 spr0525 vex2 vex2 524940 525587 + ABC transporter ATP-binding protein gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=spr0525 spr0526 spr0526 vex3 vex3 525639 527018 + peptide ABC transporter permease gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=spr0526 spr0528 spr0528 vncR vncR 527330 527986 + response regulator VncR gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=spr0528 spr0529 spr0529 vncS vncS 527983 529311 + histidine kinase VncS gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=spr0529 spr0530 spr0530 fba fba 529452 530333 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=spr0530 spr0531 spr0531 spr0531 530654 531856 - oxidoreductase Probable oxidoreductase gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=spr0531 spr0532 spr0532 glnP glnP 532102 532761 - amino acid ABC transporter permease gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=spr0532 spr0533 spr0533 glnP glnP 532771 533448 - amino acid ABC transporter permease gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=spr0533 spr0534 spr0534 glnH glnH 533461 534255 - amino acid ABC transporter amino acid-binding protein gene gene503 http://www.ncbi.nlm.nih.gov/gene/?term=spr0534 spr0535 spr0535 glnQ-truncation glnQ-truncation 534266 535024 - gene gene504 http://www.ncbi.nlm.nih.gov/gene/?term=spr0535 spr0537 spr0537 recJ recJ 535289 537523 + single-stranded-DNA-specific exonuclease RecJ gene gene505 http://www.ncbi.nlm.nih.gov/gene/?term=spr0537 spr0538 spr0538 spr0538 537698 539359 + metallo-beta-lactamase superfamily protein gene gene506 http://www.ncbi.nlm.nih.gov/gene/?term=spr0538 spr0539 spr0539 estA estA 539428 540207 + tributyrin esterase gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=spr0539 spr0540 spr0540 murM murM 540319 541539 + serine/alanine adding enzyme gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=spr0540 spr0541 spr0541 murN murN 541544 542776 + beta-lactam resistance factor gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=spr0541 spr0542 spr0542 spr0542 542892 543551 + hypothetical protein gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=spr0542 spr0543 spr0543 uvrC uvrC 543591 545435 + excinuclease ABC subunit C The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=spr0543 spr0544 spr0544 spr0544 545425 546258 + hypothetical protein gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=spr0544 spr0545 spr0545 ABC-SBP ABC-SBP 546440 547255 - glutamine ABC transporter substrate-binding protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=spr0545 spr0546 spr0546 nrd nrd 547411 548016 + nitroreductase gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=spr0546 spr0547 spr0547 pepV pepV 548029 549429 + dipeptidase PepV divalent metal ion-dependent extracellular dipeptidase%3B able to hydrolyze a broad range of dipeptides but no tri-%2C tetra-%2C or larger oligopeptides%3B differences in the amino acid specificity of the cleavage site varies between species%3B similar to succinyl-diaminopimelate desuccinylases gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=spr0547 spr0548 spr0548 spr0548 549483 550061 + hypothetical protein gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=spr0548 spr0551 spr0551 brnQ brnQ 550668 552008 + branched chain amino acid ABC transporter carrier protein gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=spr0551 spr0552 spr0552 spr0552 552212 553249 + hypothetical protein gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=spr0552 spr0553 spr0553 spr0553 553218 553721 + HIT family protein gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=spr0553 spr0554 spr0554 spr0554 553724 554440 + hypothetical protein carboxypeptidase gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=spr0554 spr0555 spr0555 rplK rplK 554749 555174 + 50S ribosomal protein L11 binds directly to 23S ribosomal RNA gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=spr0555 spr0556 spr0556 rplA rplA 555382 556071 + 50S ribosomal protein L1 in Escherichia coli and Methanococcus%2C this protein autoregulates expression%3B the binding site in the mRNA mimics the binding site in the 23S rRNA gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=spr0556 spr0557 spr0557 ABC-NBD ABC-NBD 558589 559581 + ABC transporter ATP-binding protein gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=spr0557 spr0558 spr0558 spr0558 559541 560401 + hypothetical protein gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=spr0558 spr0559 spr0559 spr0559 560403 561188 + hypothetical protein gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=spr0559 spr0560 spr0560 spr0560 561441 561686 + hypothetical protein gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=spr0560 spr0560a spr0560a spr0560a 561962 562186 - hypothetical protein gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=spr0560a spr0561 spr0561 prtA prtA 562418 568852 + cell wall-associated serine proteinase PrtA gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=spr0561 spr0562 spr0562 PTS-EII PTS-EII 569431 569952 + PTS system transporter subunit IIA gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=spr0562 spr0563 spr0563 spr0563 569990 570295 + hypothetical protein gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=spr0563 spr0564 spr0564 PTS-EII PTS-EII 570343 571818 + PTS system transporter subunit IIC gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=spr0564 spr0565 spr0565 bgaA bgaA 572123 578809 + beta-galactosidase gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=spr0565 spr0566 spr0566 spr0566 579057 579678 - gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=spr0566 spr0567 spr0567 spr0567 579666 579911 - hypothetical protein gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=spr0567 spr0568 spr0568 spr0568 580123 580482 - hypothetical protein gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=spr0568 spr0569 spr0569 spr0569 580406 581026 + hypothetical protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=spr0569 spr0570 spr0570 spr0570 581084 581530 + hypothetical protein gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=spr0570 spr0571 spr0571 spr0571 581508 582071 + hypothetical protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=spr0571 spr0572 spr0572 spr0572 582064 582318 + hypothetical protein gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=spr0572 spr0573 spr0573 nha2 nha2 582330 584384 + sodium/hydrogen exchanger family protein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=spr0573 spr0574 spr0574 spr0574 584548 585423 + ribonuclease BN gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=spr0574 spr0575 spr0575 ccdA ccdA 585634 586344 + cytochrome c-type biogenesis protein gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=spr0575 spr0576 spr0576 spr0576 586337 586930 + hypothetical protein gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=spr0576 spr0577 spr0577 msrA msrA 586941 588053 + bifunctional methionine sulfoxide reductase A/B protein this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus%3B A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress%2C S and R epimers of methionine sulfoxide%2C respectively%3B a fusion gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=spr0577 spr0578 spr0578 rr09 rr09 588303 589058 + DNA-binding response regulator gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=spr0578 spr0579 spr0579 hk09 hk09 589055 590746 + sensor histidine kinase gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=spr0579 spr0580 spr0580 spr0580 590841 591425 + hypothetical protein gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=spr0580 spr0581 spr0581 zmpB zmpB 591447 597077 + zinc metalloprotease Similar to IgA1 protease gene gene548 http://www.ncbi.nlm.nih.gov/gene/?term=spr0581 spr0582 spr0582 pabB pabB 597147 598868 + Para-aminobenzoate synthetase gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=spr0582 spr0583 spr0583 spr0583 599026 600015 + pneumococcal surface protein Similar to 1%2C4-beta-N-acetylmuramidase gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=spr0583 spr0584 spr0584 glcK glcK 600133 601110 + glucokinase gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=spr0584 spr0585 spr0585 thyA thyA 601207 602046 + thymidylate synthase ThyA%3B catalyzes formation of dTMP and 7%2C8-dihydrofolate from 5%2C10-methylenetetrahydrofolate and dUMP%3B involved in deoxyribonucleotide biosynthesis%3B there are 2 copies in some Bacilli%2C one of which appears to be phage-derived gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=spr0585 spr0586 spr0586 spr0586 602094 602264 - hypothetical protein gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=spr0586 spr0588 spr0588 miaA miaA 602334 603269 + tRNA delta(2)-isopentenylpyrophosphate transferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=spr0588 spr0589 spr0589 spr0589 603262 604500 + GTP-binding protein HflX Probable GTP-binding protein gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=spr0589 spr0590 spr0590 spr0590 604493 605116 + hypothetical protein gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=spr0590 spr0591 spr0591 spr0591 605131 606060 + ribonuclease Z member of metallo-beta-lactamase%3B the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase%3B in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not%3B associates with two zinc ions gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=spr0591 spr0592 spr0592 spr0592 606081 606836 + hypothetical protein Probable oxidoreductase gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=spr0592 spr0593 spr0593 cpsY cpsY 606890 607936 - transcriptional regulator gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=spr0593 spr0594 spr0594 spr0594 607862 608131 + hypothetical protein gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=spr0594 spr0595 spr0595 spr0595 608131 608511 + hypothetical protein gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=spr0595 spr0596 spr0596 spr0596 608630 608827 + hypothetical protein gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=spr0596 spr0597 spr0597 rsuA rsuA 608867 609592 - ribosomal small subunit pseudouridine synthase A gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=spr0597 spr0598 spr0598 typA typA 609733 611595 + elongation factor Tu family protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=spr0598 spr0599 spr0599 spr0599 611615 611869 + hypothetical protein gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=spr0599 spr0600 spr0600 spr0600 612185 612532 + hypothetical protein bacteriocin gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=spr0600 spr0601 spr0601 spr0601 612603 614624 + hypothetical protein gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=spr0601 spr0602 spr0602 ABC-NBD ABC-NBD 614626 615267 + sodium ABC transporter ATP-binding protein gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=spr0602 spr0603 spr0603 murD murD 615371 616723 + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=spr0603 spr0604 spr0604 murG murG 616727 617785 + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=spr0604 spr0605 spr0605 divIB divIB 617795 618985 + cell division protein DivIB gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=spr0605 spr0607 spr0607 spr0607 619725 620573 + hypothetical protein gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=spr0607 spr0608 spr0608 spr0608 620557 621929 + gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=spr0608 spr0609 spr0609 ABC-NBD-truncation ABC-NBD-truncation 622097 622972 + gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=spr0609 spr0611 spr0611 spr0611 622965 623678 + hypothetical protein membrane spanning protein gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=spr0611 spr0613 spr0613 pyrF pyrF 624413 625114 + orotidine 5'-phosphate decarboxylase type 1 subfamily%3B involved in last step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate to UMP and carbon dioxide%3B OMP decarboxylase%3B OMPDCase%3B OMPdecase gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=spr0613 spr0614 spr0614 pyrE pyrE 625148 625780 + orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=spr0614 spr0615 spr0615 spr0615 625960 626364 + hypothetical protein gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=spr0615 spr0616 spr0616 spr0616 626460 627224 + hypothetical protein gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=spr0616 spr0617 spr0617 spr0617 627173 627976 + hypothetical protein gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=spr0617 spr0618 spr0618 spr0618 627980 628684 + hypothetical protein gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=spr0618 spr0619 spr0619 ABC-NBD ABC-NBD 628681 629328 + ABC transporter ATP-binding protein gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=spr0619 spr0620 spr0620 ABC-SBP-truncation ABC-SBP-truncation 629408 630273 - gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=spr0620 spr0622 spr0622 glnQ glnQ 630285 631043 - amino acid ABC transporter ATP-binding protein gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=spr0622 spr0623 spr0623 glnP glnP 631044 631721 - amino acid ABC transporter permease gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=spr0623 spr0624 spr0624 glnP glnP 631681 632361 - amino acid ABC transporter permease gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=spr0624 spr0626 spr0626 lysS lysS 632850 634340 + lysyl-tRNA synthetase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=spr0626 spr0627 spr0627 lctO lctO 634965 636101 + lactate oxidase gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=spr0627 spr0628 spr0628 spr0628 636656 637324 + hypothetical protein Probable transcriptional regulator gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=spr0628 spr0629 spr0629 thiM thiM 637592 638395 + hydroxyethylthiazole kinase catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP gene gene590 http://www.ncbi.nlm.nih.gov/gene/?term=spr0629 spr0630 spr0630 thiE thiE 638397 639026 + thiamine-phosphate pyrophosphorylase gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=spr0630 spr0631 spr0631 spr0631 639551 640144 + hypothetical protein gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=spr0631 spr0632 spr0632 ABC-NBD ABC-NBD 640145 641530 + ABC transporter ATP-binding protein gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=spr0632 spr0633 spr0633 spr0633 641532 642182 + hypothetical protein gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=spr0633 spr0634 spr0634 tenA tenA 642193 642885 + extracellular enzyme gene transcriptional regulator gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=spr0634 spr0635 spr0635 spr0635 642890 643414 + hypothetical protein gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=spr0635 spr0636 spr0636 thiM thiM 643414 644217 + hydroxyethylthiazole kinase gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=spr0636 spr0637 spr0637 thiE thiE 644210 644842 + thiamine-phosphate pyrophosphorylase Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=spr0637 spr0638 spr0638 thiD thiD 645051 645842 - phosphomethylpyrimidine kinase catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=spr0638 spr0639 spr0639 copY copY 646178 646603 + COPAB ATPase metal-fist type repressor gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=spr0639 spr0640 spr0640 spr0640 646614 646985 + hypothetical protein gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=spr0640 spr0641 spr0641 ctpA ctpA 646986 649238 + copper transporter P-type ATPase gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=spr0641 spr0642 spr0642 spxB spxB 649445 651220 + pyruvate oxidase gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=spr0642 spr0643 spr0643 spr0643 651331 651678 + hypothetical protein gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=spr0643 spr0644 spr0644 transposase_C transposase_C 651795 652448 - transposase gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=spr0644 spr0645 spr0645 spr0645 652336 652683 - hypothetical protein gene gene606 http://www.ncbi.nlm.nih.gov/gene/?term=spr0645 spr0647 spr0647 pmi pmi 653533 654477 + mannose-6-phosphate isomerase gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=spr0647 spr0648 spr0648 NS_transporter NS_transporter 654580 655971 - sodium-dependent transporter gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=spr0648 spr0649 spr0649 mta mta 656131 656793 + regulator of the multidrug efflux pump pmrA gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=spr0649 spr0650 spr0650 spr0650 656822 657277 - hypothetical protein Similar to mutator protein MutT gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=spr0650 spr0651 spr0651 spr0651 657297 658490 - hypothetical protein gene gene611 http://www.ncbi.nlm.nih.gov/gene/?term=spr0651 spr0652 spr0652 spr0652 658531 659376 - hypothetical protein gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=spr0652 spr0653 spr0653 spr0653 659501 660058 + hypothetical protein Probable transcriptional regulator gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=spr0653 spr0654 spr0654 comEB comEB 660077 660544 + cytidine and deoxycytidylate deaminase late competence operon required for DNA binding and uptake gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=spr0654 spr0655 spr0655 upp upp 660612 661262 + uracil phosphoribosyltransferase Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=spr0655 spr0656 spr0656 clpP clpP 661436 662026 + ATP-dependent Clp protease proteolytic subunit hydrolyzes proteins to small peptides%3B with the ATPase subunits ClpA or ClpX%2C ClpP degrades specific substrates gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=spr0656 spr0657 spr0657 spr0657 662105 662353 + hypothetical protein gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=spr0657 spr0658 spr0658 spr0658 662219 662449 - hypothetical protein gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=spr0658 spr0659 spr0659 livJ livJ 662455 663615 + branched chain amino acid ABC transporter substrate+B481-binding protein gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=spr0659 spr0660 spr0660 livH livH 663874 664752 + branched chain amino acid ABC transporter permease gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=spr0660 spr0661 spr0661 livM livM 664756 665712 + branched chain amino acid ABC transporter permease gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=spr0661 spr0662 spr0662 livG livG 665712 666476 + branched chain amino acid ABC transporter ATP-binding protein gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=spr0662 spr0663 spr0663 livF livF 666476 667186 + branched chain amino acid ABC transporter ATP-binding protein gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=spr0663 spr0664 spr0664 spr0664 667600 668256 + acetoin utilization protein AcuB gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=spr0664 spr0665 spr0665 prfB prfB 668470 669459 + peptide chain release factor 2 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2%3B in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism%3B this protein is similar to release factor 1 gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=spr0665 spr0666 spr0666 ftsE ftsE 669477 670169 + ABC transporter ATP-binding protein gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=spr0666 spr0667 spr0667 ftsX ftsX 670099 671088 + cell division ABC transporter permease FtsX gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=spr0667 spr0668 spr0668 ptsG ptsG 671374 673554 + PTS system transporter subunit IIABC gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=spr0668 spr0669 spr0669 spr0669 673606 674421 + hypothetical protein gene gene629 http://www.ncbi.nlm.nih.gov/gene/?term=spr0669 spr0670 spr0670 rheB rheB 674561 675904 + ATP-dependent RNA helicase gene gene630 http://www.ncbi.nlm.nih.gov/gene/?term=spr0670 spr0671 spr0671 metK metK 676119 677309 + S-adenosylmethionine synthetase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=spr0671 spr0672 spr0672 pyrDA pyrDA 677862 678797 + dihydroorotate dehydrogenase 1A catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=spr0672 spr0673 spr0673 holA holA 678831 679868 + DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=spr0673 spr0674 spr0674 sodA sodA 680041 680646 + superoxide dismutase gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=spr0674 spr0675 spr0675 spr0675 680803 681333 + hypothetical protein gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=spr0675 spr0676 spr0676 spr0676 681354 682439 + ribosomal RNA large subunit methyltransferase N 23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=spr0676 spr0677 spr0677 spr0677 682441 682908 + hypothetical protein gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=spr0677 spr0678 spr0678 ABC-NBD ABC-NBD 682910 684451 + ABC transporter ATP-binding protein gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=spr0678 spr0679 spr0679 ppiA ppiA 684508 685311 - peptidyl-prolyl cis-trans isomerase gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=spr0679 spr0680 spr0680 spr0680 685395 685616 - hypothetical protein gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=spr0680 spr0681 spr0681 spr0681 685504 685734 - hypothetical protein gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=spr0681 spr0682 spr0682 rpsP rpsP 686482 686754 + 30S ribosomal protein S16 binds to lower part of 30S body where it stabilizes two domains%3B required for efficient assembly of 30S%3B in Escherichia coli this protein has nuclease activity gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=spr0682 spr0683 spr0683 spr0683 686774 687013 + hypothetical protein gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=spr0683 spr0684 spr0684 spr0684 687590 688304 + gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=spr0684 spr0686 spr0686 rimM rimM 688409 688927 + 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=spr0686 spr0687 spr0687 trmD trmD 688917 689636 + tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=spr0687 spr0688 spr0688 spr0688 689648 689986 + hypothetical protein gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=spr0688 spr0689 spr0689 spr0689 690017 690337 - hypothetical protein gene gene648 http://www.ncbi.nlm.nih.gov/gene/?term=spr0689 spr0690 spr0690 spr0690 690411 690650 + hypothetical protein gene gene649 http://www.ncbi.nlm.nih.gov/gene/?term=spr0690 spr0691 spr0691 bioY bioY 690854 691390 - biotin synthase gene gene650 http://www.ncbi.nlm.nih.gov/gene/?term=spr0691 spr0692 spr0692 gor gor 691587 692933 - glutathione reductase catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense gene gene651 http://www.ncbi.nlm.nih.gov/gene/?term=spr0692 spr0693 spr0693 spr0693 693198 694397 + hypothetical protein gene gene652 http://www.ncbi.nlm.nih.gov/gene/?term=spr0693 spr0694 spr0694 ABC-NBD ABC-NBD 694381 695082 + ABC transporter ATP-binding protein gene gene653 http://www.ncbi.nlm.nih.gov/gene/?term=spr0694 spr0695 spr0695 spr0695 695084 696343 + hypothetical protein gene gene654 http://www.ncbi.nlm.nih.gov/gene/?term=spr0695 spr0696 spr0696 metG metG 696467 698464 + methionyl-tRNA synthetase methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content gene gene655 http://www.ncbi.nlm.nih.gov/gene/?term=spr0696 spr0696a spr0696a spr0696a 698514 698705 + hypothetical protein gene gene656 http://www.ncbi.nlm.nih.gov/gene/?term=spr0696a spr0697 spr0697 spr0697 698792 699115 + hypothetical protein gene gene657 http://www.ncbi.nlm.nih.gov/gene/?term=spr0697 spr0698 spr0698 spr0698 699119 699994 + hypothetical protein gene gene658 http://www.ncbi.nlm.nih.gov/gene/?term=spr0698 spr0699 spr0699 spr0699 700006 700935 + hypothetical protein gene gene659 http://www.ncbi.nlm.nih.gov/gene/?term=spr0699 spr0700 spr0700 spr0700 701014 701271 + hypothetical protein gene gene660 http://www.ncbi.nlm.nih.gov/gene/?term=spr0700 spr0701 spr0701 fabG fabG 701264 701962 + 3-ketoacyl-ACP reductase Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene661 http://www.ncbi.nlm.nih.gov/gene/?term=spr0701 spr0702 spr0702 spr0702 701973 702452 + MutT/nudix family protein gene gene662 http://www.ncbi.nlm.nih.gov/gene/?term=spr0702 spr0703 spr0703 spr0703 702460 703188 + hypothetical protein gene gene663 http://www.ncbi.nlm.nih.gov/gene/?term=spr0703 spr0704 spr0704 spr0704 703224 704099 + hypothetical protein gene gene664 http://www.ncbi.nlm.nih.gov/gene/?term=spr0704 spr0705 spr0705 spr0705 704074 704514 + hypothetical protein gene gene665 http://www.ncbi.nlm.nih.gov/gene/?term=spr0705 spr0706 spr0706 pepN pepN 704637 707183 + aminopeptidase gene gene666 http://www.ncbi.nlm.nih.gov/gene/?term=spr0706 spr0707 spr0707 ciaR ciaR 707226 707966 + DNA-binding response regulator CiaR gene gene667 http://www.ncbi.nlm.nih.gov/gene/?term=spr0707 spr0708 spr0708 ciaH ciaH 707956 709290 + sensor histidine kinase CiaH gene gene668 http://www.ncbi.nlm.nih.gov/gene/?term=spr0708 spr0709 spr0709 spr0709 709324 709611 - hypothetical protein gene gene669 http://www.ncbi.nlm.nih.gov/gene/?term=spr0709 spr0710 spr0710 spr0710 709610 710680 + hypothetical protein Similar to protease gene gene670 http://www.ncbi.nlm.nih.gov/gene/?term=spr0710 spr0711 spr0711 dinG dinG 710880 713330 + bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon unwinds DNA gene gene671 http://www.ncbi.nlm.nih.gov/gene/?term=spr0711 spr0712 spr0712 rodA rodA 713340 714590 + rod shape-determining protein RodA gene gene672 http://www.ncbi.nlm.nih.gov/gene/?term=spr0712 spr0713 spr0713 thiJ thiJ 714601 715155 + 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein gene gene673 http://www.ncbi.nlm.nih.gov/gene/?term=spr0713 spr0714 spr0714 gph gph 715231 715803 + phosphoglycolate phosphatase gene gene674 http://www.ncbi.nlm.nih.gov/gene/?term=spr0714 spr0715 spr0715 gyrB gyrB 715818 717764 + DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene675 http://www.ncbi.nlm.nih.gov/gene/?term=spr0715 spr0716 spr0716 ezrA ezrA 717819 719573 + septation ring formation regulator EzrA acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation gene gene676 http://www.ncbi.nlm.nih.gov/gene/?term=spr0716 spr0717 spr0717 transposase_C transposase_C 720316 720720 + transposase gene gene677 http://www.ncbi.nlm.nih.gov/gene/?term=spr0717 spr0718 spr0718 transposase_D transposase_D 720608 721261 + transposase gene gene678 http://www.ncbi.nlm.nih.gov/gene/?term=spr0718 spr0719 spr0719 transposase_E transposase_E 721347 721634 - gene gene679 http://www.ncbi.nlm.nih.gov/gene/?term=spr0719 spr0720 spr0720 spr0720 721895 722194 - hypothetical protein gene gene680 http://www.ncbi.nlm.nih.gov/gene/?term=spr0720 spr0721 spr0721 spr0721 722359 722781 - MutT/nudix family protein gene gene681 http://www.ncbi.nlm.nih.gov/gene/?term=spr0721 spr0722 spr0722 transposase_A transposase_A 722874 723221 + transposase gene gene682 http://www.ncbi.nlm.nih.gov/gene/?term=spr0722 spr0725 spr0725 clpE clpE 723946 726204 - ATP dependent protease gene gene683 http://www.ncbi.nlm.nih.gov/gene/?term=spr0725 spr0726 spr0726 spr0726 726433 726663 - hypothetical protein gene gene684 http://www.ncbi.nlm.nih.gov/gene/?term=spr0726 spr0727 spr0727 glnP glnP 726847 727536 + amino acid ABC transporter permease gene gene685 http://www.ncbi.nlm.nih.gov/gene/?term=spr0727 spr0728 spr0728 glnQ glnQ 727536 728270 + amino acid ABC transporter ATP-binding protein gene gene686 http://www.ncbi.nlm.nih.gov/gene/?term=spr0728 spr0729 spr0729 folD folD 728361 729281 + bifunctional 5%2C10-methylene-tetrahydrofolate dehydrogenase/ 5%2C10-methylene-tetrahydrofolate cyclohydrolase catalyzes the formation of 5%2C10-methenyltetrahydrofolate from 5%2C10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5%2C10-methenyltetrahydrofolate gene gene687 http://www.ncbi.nlm.nih.gov/gene/?term=spr0729 spr0730 spr0730 spr0730 729423 730295 + hypothetical protein gene gene688 http://www.ncbi.nlm.nih.gov/gene/?term=spr0730 spr0731 spr0731 rpiA rpiA 730520 731260 + ribose-5-phosphate isomerase A Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway gene gene689 http://www.ncbi.nlm.nih.gov/gene/?term=spr0731 spr0732 spr0732 deoB deoB 731211 732485 + phosphopentomutase catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose gene gene690 http://www.ncbi.nlm.nih.gov/gene/?term=spr0732 spr0733 spr0733 spr0733 732487 733029 + gene gene691 http://www.ncbi.nlm.nih.gov/gene/?term=spr0733 spr0734 spr0734 pnp pnp 733045 733854 + purine nucleoside phosphorylase catalyzes the formation of a purine and ribose phosphate from a purine nucleoside%3B in E. coli this enzyme functions in xanthosine degradation gene gene692 http://www.ncbi.nlm.nih.gov/gene/?term=spr0734 spr0735 spr0735 spr0735 734330 735310 + gene gene693 http://www.ncbi.nlm.nih.gov/gene/?term=spr0735 spr0737 spr0737 spr0737 735335 735847 + hemolysin-like protein Related to a cytolysin gene gene694 http://www.ncbi.nlm.nih.gov/gene/?term=spr0737 spr0738 spr0738 deoD deoD 736505 737215 + purine nucleoside phosphorylase catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate gene gene695 http://www.ncbi.nlm.nih.gov/gene/?term=spr0738 spr0739 spr0739 flaR flaR 737238 737762 - topology modulation protein gene gene696 http://www.ncbi.nlm.nih.gov/gene/?term=spr0739 spr0740 spr0740 rpsT rpsT 737815 738051 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene697 http://www.ncbi.nlm.nih.gov/gene/?term=spr0740 spr0741 spr0741 coaA coaA 738119 739069 - pantothenate kinase catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis gene gene698 http://www.ncbi.nlm.nih.gov/gene/?term=spr0741 spr0742 spr0742 spr0742 739237 739677 + hypothetical protein gene gene699 http://www.ncbi.nlm.nih.gov/gene/?term=spr0742 spr0743 spr0743 spr0743 739884 740474 + hypothetical protein gene gene700 http://www.ncbi.nlm.nih.gov/gene/?term=spr0743 spr0744 spr0744 pdp pdp 740471 741748 + pyrimidine-nucleoside phosphorylase Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway gene gene701 http://www.ncbi.nlm.nih.gov/gene/?term=spr0744 spr0745 spr0745 deoC deoC 741766 742428 + deoxyribose-phosphate aldolase catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate gene gene702 http://www.ncbi.nlm.nih.gov/gene/?term=spr0745 spr0746 spr0746 cdd cdd 742415 742804 + cytidine deaminase Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis gene gene703 http://www.ncbi.nlm.nih.gov/gene/?term=spr0746 spr0747 spr0747 spr0747 742822 743946 + hypothetical protein Similar to basic membrane protein A from Lactococcus lactis subsp. lactis gene gene704 http://www.ncbi.nlm.nih.gov/gene/?term=spr0747 spr0748 spr0748 ABC-NBD ABC-NBD 744090 745625 + sugar ABC transporter ATP-binding protein gene gene705 http://www.ncbi.nlm.nih.gov/gene/?term=spr0748 spr0749 spr0749 ABC-MSP ABC-MSP 745591 746676 + sugar ABC transporter permease gene gene706 http://www.ncbi.nlm.nih.gov/gene/?term=spr0749 spr0750 spr0750 ABC-MSP ABC-MSP 746679 747635 + sugar ABC transporter permease gene gene707 http://www.ncbi.nlm.nih.gov/gene/?term=spr0750 spr0751 spr0751 IS861-truncation IS861-truncation 747720 748235 + gene gene708 http://www.ncbi.nlm.nih.gov/gene/?term=spr0751 spr0753 spr0753 IS861-truncation IS861-truncation 748235 749067 + gene gene709 http://www.ncbi.nlm.nih.gov/gene/?term=spr0753 spr0755 spr0755 spr0755 749110 749751 - glycerol-3-phosphate acyltransferase PlsY involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis%3B functions with PlsX gene gene710 http://www.ncbi.nlm.nih.gov/gene/?term=spr0755 spr0756 spr0756 parE parE 749887 751830 + DNA topoisomerase IV subunit B decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene711 http://www.ncbi.nlm.nih.gov/gene/?term=spr0756 spr0757 spr0757 parC parC 752241 754721 + DNA topoisomerase IV subunit A decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling gene gene712 http://www.ncbi.nlm.nih.gov/gene/?term=spr0757 spr0758 spr0758 ilvE ilvE 754851 755873 + branched-chain amino acid aminotransferase catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids gene gene713 http://www.ncbi.nlm.nih.gov/gene/?term=spr0758 spr0760 spr0760 spr0760 756677 757387 + hypothetical protein integral membrane protein gene gene714 http://www.ncbi.nlm.nih.gov/gene/?term=spr0760 spr0761 spr0761 spr0761 757384 758307 + hypothetical protein membrane protein gene gene715 http://www.ncbi.nlm.nih.gov/gene/?term=spr0761 spr0762 spr0762 pcp pcp 758322 758966 + pyrrolidone-carboxylate peptidase catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline gene gene716 http://www.ncbi.nlm.nih.gov/gene/?term=spr0762 spr0763 spr0763 spr0763 759134 759364 + hypothetical protein gene gene717 http://www.ncbi.nlm.nih.gov/gene/?term=spr0763 spr0764 spr0764 rpsA rpsA 759737 760939 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene720 http://www.ncbi.nlm.nih.gov/gene/?term=spr0764 spr0765 spr0765 IS1167-truncation IS1167-truncation 761074 761602 - gene gene721 http://www.ncbi.nlm.nih.gov/gene/?term=spr0765 spr0767 spr0767 IS1167 IS1167 761883 762401 - transposase gene gene722 http://www.ncbi.nlm.nih.gov/gene/?term=spr0767 spr0768 spr0768 spr0768 762595 763092 + hypothetical protein gene gene723 http://www.ncbi.nlm.nih.gov/gene/?term=spr0768 spr0769 spr0769 dnaX dnaX 763092 764747 + DNA polymerase III subunits gamma and tau catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA gene gene724 http://www.ncbi.nlm.nih.gov/gene/?term=spr0769 spr0770 spr0770 spr0770 764775 764969 + hypothetical protein gene gene725 http://www.ncbi.nlm.nih.gov/gene/?term=spr0770 spr0771 spr0771 ABC-NBD ABC-NBD 765098 765889 + ABC transporter ATP-binding protein gene gene726 http://www.ncbi.nlm.nih.gov/gene/?term=spr0771 spr0772 spr0772 spr0772 765917 767179 + hypothetical protein gene gene727 http://www.ncbi.nlm.nih.gov/gene/?term=spr0772 spr0773 spr0773 spr0773 767190 768416 + hypothetical protein Probable class-V aminotransferase gene gene728 http://www.ncbi.nlm.nih.gov/gene/?term=spr0773 spr0774 spr0774 nifU nifU 768403 768843 + NifU protein gene gene729 http://www.ncbi.nlm.nih.gov/gene/?term=spr0774 spr0775 spr0775 spr0775 768897 770309 + hypothetical protein gene gene730 http://www.ncbi.nlm.nih.gov/gene/?term=spr0775 spr0776 spr0776 dacA dacA 770508 771749 - D-alanyl-D-alanine carboxypeptidase gene gene731 http://www.ncbi.nlm.nih.gov/gene/?term=spr0776 spr0777 spr0777 spr0777 771852 772961 + hypothetical protein permease gene gene732 http://www.ncbi.nlm.nih.gov/gene/?term=spr0777 spr0778 spr0778 fruR fruR 774386 775126 + lactose PTS system repressor gene gene735 http://www.ncbi.nlm.nih.gov/gene/?term=spr0778 spr0779 spr0779 fruB fruB 775123 776034 + 1-phosphofructokinase gene gene736 http://www.ncbi.nlm.nih.gov/gene/?term=spr0779 spr0780 spr0780 fruA fruA 776031 777983 + PTS system fructose specific transporter subunit IIABC gene gene737 http://www.ncbi.nlm.nih.gov/gene/?term=spr0780 spr0781 spr0781 ftsK ftsK 778069 780372 + SpoE family protein gene gene738 http://www.ncbi.nlm.nih.gov/gene/?term=spr0781 spr0782 spr0782 spr0782 780417 780950 - hypothetical protein gene gene739 http://www.ncbi.nlm.nih.gov/gene/?term=spr0782 spr0783 spr0783 spr0783 780983 782125 + pyridoxal-phosphate dependent aminotransferase gene gene740 http://www.ncbi.nlm.nih.gov/gene/?term=spr0783 spr0784 spr0784 thiI thiI 782134 783348 + thiamine biosynthesis protein ThiI Required for the synthesis of the thiazole moiety gene gene741 http://www.ncbi.nlm.nih.gov/gene/?term=spr0784 spr0785 spr0785 spr0785 783459 784307 + hypothetical protein gene gene742 http://www.ncbi.nlm.nih.gov/gene/?term=spr0785 spr0786 spr0786 spr0786 784329 785068 + gene gene743 http://www.ncbi.nlm.nih.gov/gene/?term=spr0786 spr0789 spr0789 spr0789 785081 786247 + hypothetical protein gene gene744 http://www.ncbi.nlm.nih.gov/gene/?term=spr0789 spr0790 spr0790 hsdM hsdM 786755 788248 + type I restriction-modification system M subunit gene gene745 http://www.ncbi.nlm.nih.gov/gene/?term=spr0790 spr0791 spr0791 hsdS hsdS 788261 788872 + type I restriction-modification system S subunit gene gene746 http://www.ncbi.nlm.nih.gov/gene/?term=spr0791 spr0792 spr0792 hsdR hsdR 788951 792301 + type I restriction-modification system R subunit gene gene747 http://www.ncbi.nlm.nih.gov/gene/?term=spr0792 spr0792a spr0792a spr0792a 792572 792772 + hypothetical protein gene gene748 http://www.ncbi.nlm.nih.gov/gene/?term=spr0792a spr0793 spr0793 argR argR 792887 793357 - arginine repressor ArgR gene gene749 http://www.ncbi.nlm.nih.gov/gene/?term=spr0793 spr0794 spr0794 pepXP pepXP 793374 795761 - x-prolyl-dipeptidyl aminopeptidase catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue gene gene750 http://www.ncbi.nlm.nih.gov/gene/?term=spr0794 spr0795 spr0795 dnaE dnaE 795966 799094 + DNA polymerase III DnaE Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria. gene gene751 http://www.ncbi.nlm.nih.gov/gene/?term=spr0795 spr0796 spr0796 pfkA pfkA 799177 800184 + 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene752 http://www.ncbi.nlm.nih.gov/gene/?term=spr0796 spr0797 spr0797 pykF pykF 800243 801748 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene753 http://www.ncbi.nlm.nih.gov/gene/?term=spr0797 spr0799 spr0799 spr0799 803555 804427 + hypothetical protein gene gene754 http://www.ncbi.nlm.nih.gov/gene/?term=spr0799 spr0801 spr0801 IS1381-truncation IS1381-truncation 804534 804917 - gene gene755 http://www.ncbi.nlm.nih.gov/gene/?term=spr0801 spr0802 spr0802 spr0802 805060 805371 + hypothetical protein gene gene756 http://www.ncbi.nlm.nih.gov/gene/?term=spr0802 spr0803 spr0803 spr0803 805375 806091 + hypothetical protein gene gene757 http://www.ncbi.nlm.nih.gov/gene/?term=spr0803 spr0804 spr0804 spr0804 806221 807036 - hypothetical protein gene gene758 http://www.ncbi.nlm.nih.gov/gene/?term=spr0804 spr0805 spr0805 spr0805 807033 807938 - hypothetical protein gene gene759 http://www.ncbi.nlm.nih.gov/gene/?term=spr0805 spr0806 spr0806 spr0806 808280 809649 + gene gene760 http://www.ncbi.nlm.nih.gov/gene/?term=spr0806 spr0808 spr0808 tex tex 809733 811880 + toxin expression transcriptional accessory protein gene gene761 http://www.ncbi.nlm.nih.gov/gene/?term=spr0808 spr0809 spr0809 spr0809 811867 812316 + hypothetical protein gene gene762 http://www.ncbi.nlm.nih.gov/gene/?term=spr0809 spr0810 spr0810 spr0810 812345 812647 + hypothetical protein gene gene763 http://www.ncbi.nlm.nih.gov/gene/?term=spr0810 spr0811 spr0811 spr0811 813001 813192 - hypothetical protein gene gene764 http://www.ncbi.nlm.nih.gov/gene/?term=spr0811 spr0812 spr0812 ABC-NBD ABC-NBD 813563 814378 + ABC transporter ATP-binding protein gene gene765 http://www.ncbi.nlm.nih.gov/gene/?term=spr0812 spr0813 spr0813 ABC-MSD ABC-MSD 814380 816368 + ABC transporter permease gene gene766 http://www.ncbi.nlm.nih.gov/gene/?term=spr0813 spr0814 spr0814 spr0814 816411 817001 - hypothetical protein gene gene767 http://www.ncbi.nlm.nih.gov/gene/?term=spr0814 spr0815 spr0815 spr0815 817081 818001 - transposase gene gene768 http://www.ncbi.nlm.nih.gov/gene/?term=spr0815 spr0816 spr0816 cad cad 818663 820138 + lysine decarboxylase gene gene769 http://www.ncbi.nlm.nih.gov/gene/?term=spr0816 spr0817 spr0817 transposase_F transposase_F 820104 820819 - gene gene770 http://www.ncbi.nlm.nih.gov/gene/?term=spr0817 spr0819 spr0819 speE speE 821075 821935 + spermidine synthase catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine gene gene771 http://www.ncbi.nlm.nih.gov/gene/?term=spr0819 spr0820 spr0820 spr0820 821932 823191 + hypothetical protein gene gene772 http://www.ncbi.nlm.nih.gov/gene/?term=spr0820 spr0821 spr0821 nspC nspC 823191 824318 + carboxynorspermidine decarboxylase gene gene773 http://www.ncbi.nlm.nih.gov/gene/?term=spr0821 spr0822 spr0822 spr0822 824315 825400 + agmatine deiminase catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis gene gene774 http://www.ncbi.nlm.nih.gov/gene/?term=spr0822 spr0823 spr0823 but but 825410 826285 + beta-alanine synthase or beta-ureidopropionase gene gene775 http://www.ncbi.nlm.nih.gov/gene/?term=spr0823 spr0824 spr0824 spr0824 826466 827275 - Cof family protein gene gene776 http://www.ncbi.nlm.nih.gov/gene/?term=spr0824 spr0825 spr0825 spr0825 827547 827768 + hypothetical protein gene gene777 http://www.ncbi.nlm.nih.gov/gene/?term=spr0825 spr0826 spr0826 spr0826 827822 828493 + hypothetical protein gene gene778 http://www.ncbi.nlm.nih.gov/gene/?term=spr0826 spr0828 spr0828 cpsY cpsY 828735 829643 + regulatory function on capsule expression in group B streptococci gene gene779 http://www.ncbi.nlm.nih.gov/gene/?term=spr0828 spr0829 spr0829 lspA lspA 829640 830101 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene780 http://www.ncbi.nlm.nih.gov/gene/?term=spr0829 spr0830 spr0830 rluD rluD 830091 830978 + ribosomal large subunit pseudouridine synthase D gene gene781 http://www.ncbi.nlm.nih.gov/gene/?term=spr0830 spr0831 spr0831 lytD lytD 830981 832864 + choline binding protein E gene gene782 http://www.ncbi.nlm.nih.gov/gene/?term=spr0831 spr0832 spr0832 proB proB 832944 834074 + gamma-glutamyl kinase catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis gene gene783 http://www.ncbi.nlm.nih.gov/gene/?term=spr0832 spr0833 spr0833 proA proA 834084 835346 + gamma-glutamyl phosphate reductase Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway gene gene784 http://www.ncbi.nlm.nih.gov/gene/?term=spr0833 spr0834 spr0834 proC proC 835350 836147 + pyrroline-5-carboxylate reductase gene gene785 http://www.ncbi.nlm.nih.gov/gene/?term=spr0834 spr0835 spr0835 tmk tmk 836263 836901 + thymidylate kinase catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) gene gene786 http://www.ncbi.nlm.nih.gov/gene/?term=spr0835 spr0836 spr0836 holB holB 836898 837788 + DNA polymerase III subunit delta' catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA. gene gene787 http://www.ncbi.nlm.nih.gov/gene/?term=spr0836 spr0837 spr0837 spr0837 837801 838145 + DNA replication intiation control protein YabA in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation%3B interacts with DnaN and DnaA gene gene788 http://www.ncbi.nlm.nih.gov/gene/?term=spr0837 spr0838 spr0838 spr0838 838148 839017 + hypothetical protein gene gene789 http://www.ncbi.nlm.nih.gov/gene/?term=spr0838 spr0839 spr0839 spr0839 839217 839762 + hypothetical protein gene gene790 http://www.ncbi.nlm.nih.gov/gene/?term=spr0839 spr0840 spr0840 spr0840 839871 840518 + hypothetical protein gene gene791 http://www.ncbi.nlm.nih.gov/gene/?term=spr0840 spr0841 spr0841 IS1381 IS1381 840507 840896 - tranposase gene gene792 http://www.ncbi.nlm.nih.gov/gene/?term=spr0841 spr0842 spr0842 IS1381 IS1381 840922 841311 - tranposase gene gene793 http://www.ncbi.nlm.nih.gov/gene/?term=spr0842 spr0844 spr0844 gidA gidA 841805 843139 + tRNA (uracil-5-)-methyltransferase Gid TrmFO%3B Gid%3B glucose-inhibited division protein%3B similar to GidA%3B the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant%3B modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine gene gene794 http://www.ncbi.nlm.nih.gov/gene/?term=spr0844 spr0845 spr0845 pyrH pyrH 843217 843960 + uridylate kinase Catalyzes the phosphorylation of UMP to UDP gene gene795 http://www.ncbi.nlm.nih.gov/gene/?term=spr0845 spr0846 spr0846 frr frr 843969 844526 + ribosome recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene796 http://www.ncbi.nlm.nih.gov/gene/?term=spr0846 spr0847 spr0847 spr0847 844547 845440 + hypothetical protein gene gene797 http://www.ncbi.nlm.nih.gov/gene/?term=spr0847 spr0848 spr0848 spr0848 845449 845664 + hypothetical protein gene gene798 http://www.ncbi.nlm.nih.gov/gene/?term=spr0848 spr0849 spr0849 phoL phoL 845750 846718 + PhoH family protein gene gene799 http://www.ncbi.nlm.nih.gov/gene/?term=spr0849 spr0850 spr0850 spr0850 846911 847411 + hypothetical protein gene gene800 http://www.ncbi.nlm.nih.gov/gene/?term=spr0850 spr0851 spr0851 spr0851 847414 847740 + gene gene801 http://www.ncbi.nlm.nih.gov/gene/?term=spr0851 spr0852 spr0852 ald-truncation ald-truncation 848041 849152 - gene gene802 http://www.ncbi.nlm.nih.gov/gene/?term=spr0852 spr0855 spr0855 spr0855 849329 849898 + hypothetical protein Probable acetyl transferase gene gene803 http://www.ncbi.nlm.nih.gov/gene/?term=spr0855 spr0856 spr0856 celA celA 849966 850616 + competence protein CelA Competence induced%3B comE-like protein A also known as CilE%3B DNA uptake by homology gene gene804 http://www.ncbi.nlm.nih.gov/gene/?term=spr0856 spr0857 spr0857 celB celB 850600 852840 + competence protein CelB Competence induced%3B comE-like protein B%3B DNA uptake by homology gene gene805 http://www.ncbi.nlm.nih.gov/gene/?term=spr0857 spr0859 spr0859 spr0859 853239 853826 + gene gene806 http://www.ncbi.nlm.nih.gov/gene/?term=spr0859 spr0860 spr0860 spr0860 853830 855011 + hypothetical protein gene gene807 http://www.ncbi.nlm.nih.gov/gene/?term=spr0860 spr0861 spr0861 infC infC 855261 855848 + translation initiation factor IF-3 IF-3 has several functions that are required and promote translation initiation including%3B preventing association of 70S by binding to 30S%3B monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites%3B stimulates codon-anticodon interactions at P-site%3B involved in moving mRNA to the P-site%3B and in recycling subunits gene gene808 http://www.ncbi.nlm.nih.gov/gene/?term=spr0861 spr0862 spr0862 rpmI rpmI 855881 856081 + 50S ribosomal protein L35 gene gene809 http://www.ncbi.nlm.nih.gov/gene/?term=spr0862 spr0863 spr0863 rplT rplT 856133 856492 + 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene810 http://www.ncbi.nlm.nih.gov/gene/?term=spr0863 spr0864 spr0864 lguL lguL 856499 856930 + lactoylglutathione lyase gene gene811 http://www.ncbi.nlm.nih.gov/gene/?term=spr0864 spr0865 spr0865 pyrDII pyrDII 857180 857980 + dihydroorotate dehydrogenase electron transfer subunit responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) gene gene812 http://www.ncbi.nlm.nih.gov/gene/?term=spr0865 spr0866 spr0866 pyrD pyrD 857991 858929 + dihydroorotate dehydrogenase 1B catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%2C using a flavin nucleotide as an essential cofactor%3B subclass 1B is a heterotetramer consisting of two PyrDB subunits%2C similar to the PyrDA subunits and two PyrK subunits gene gene813 http://www.ncbi.nlm.nih.gov/gene/?term=spr0866 spr0867 spr0867 lytB lytB 858971 861136 + endo-beta-N-acetylglucosaminidase gene gene814 http://www.ncbi.nlm.nih.gov/gene/?term=spr0867 spr0868 spr0868 flpA flpA 861197 862879 - adherence and virulence protein A gene gene815 http://www.ncbi.nlm.nih.gov/gene/?term=spr0868 spr0869 spr0869 spr0869 862957 863454 + metalloprotease gene gene816 http://www.ncbi.nlm.nih.gov/gene/?term=spr0869 spr0870 spr0870 dgkA dgkA 863435 863830 + diacylglycerol kinase gene gene817 http://www.ncbi.nlm.nih.gov/gene/?term=spr0870 spr0871 spr0871 era era 863847 864746 + GTP-binding protein Era Era%3B Escherichia coli Ras-like protein%3B Bex%3B Bacillus Era-complementing segment%3B essential protein in Escherichia coli that is involved in many cellular processes%3B GTPase%3B binds the cell membrane through apparent C-terminal domain%3B mutants are arrested during the cell cycle%3B Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome gene gene818 http://www.ncbi.nlm.nih.gov/gene/?term=spr0871 spr0872 spr0872 mutM mutM 864795 865619 + formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene819 http://www.ncbi.nlm.nih.gov/gene/?term=spr0872 spr0873 spr0873 coaE coaE 865592 866224 + dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene820 http://www.ncbi.nlm.nih.gov/gene/?term=spr0873 spr0875 spr0875 pmrA pmrA 866211 867410 + major facilitator superfamily multi-drug resistance efflux pump gene gene821 http://www.ncbi.nlm.nih.gov/gene/?term=spr0875 spr0876 spr0876 rpmG rpmG 867410 867559 + 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene822 http://www.ncbi.nlm.nih.gov/gene/?term=spr0876 spr0877 spr0877 secG secG 867599 867832 + preprotein translocase subunit SecG gene gene823 http://www.ncbi.nlm.nih.gov/gene/?term=spr0877 spr0878 spr0878 rnr rnr 867934 870288 + exoribonuclease R gene gene824 http://www.ncbi.nlm.nih.gov/gene/?term=spr0878 spr0879 spr0879 smpB smpB 870251 870718 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene825 http://www.ncbi.nlm.nih.gov/gene/?term=spr0879 spr0880 spr0880 tehB tehB 870728 871594 + tellurite resistance protein TehB with TehA confers resistance to tellurite gene gene826 http://www.ncbi.nlm.nih.gov/gene/?term=spr0880 spr0881 spr0881 coiA coiA 871667 872620 + competence protein CoiA Competence induced protein A gene gene827 http://www.ncbi.nlm.nih.gov/gene/?term=spr0881 spr0882 spr0882 pepB pepB 872639 874441 + oligoendopeptidase F gene gene828 http://www.ncbi.nlm.nih.gov/gene/?term=spr0882 spr0883 spr0883 spr0883 874443 875156 + O-methyltransferase Probable methyltransferase gene gene829 http://www.ncbi.nlm.nih.gov/gene/?term=spr0883 spr0884 spr0884 prsA prsA 875223 876164 + foldase PrsA cis/trans isomerase of peptidylprolyl%3B PPIase%3B membrane-bound lipoprotein gene gene830 http://www.ncbi.nlm.nih.gov/gene/?term=spr0884 spr0885 spr0885 IS861-truncation IS861-truncation 876270 876623 - gene gene831 http://www.ncbi.nlm.nih.gov/gene/?term=spr0885 spr0887 spr0887 gpmB gpmB 877383 878003 - phosphoglycerate mutase gene gene832 http://www.ncbi.nlm.nih.gov/gene/?term=spr0887 spr0888 spr0888 ebsC ebsC 878003 878485 - regulatory protein gene gene833 http://www.ncbi.nlm.nih.gov/gene/?term=spr0888 spr0889 spr0889 spr0889 878485 879327 - hypothetical protein gene gene834 http://www.ncbi.nlm.nih.gov/gene/?term=spr0889 spr0890 spr0890 spr0890 879422 880222 - hypothetical protein gene gene835 http://www.ncbi.nlm.nih.gov/gene/?term=spr0890 spr0891 spr0891 glmU glmU 880306 881745 + bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene836 http://www.ncbi.nlm.nih.gov/gene/?term=spr0891 spr0892 spr0892 spr0892 881755 882300 + hypothetical protein gene gene837 http://www.ncbi.nlm.nih.gov/gene/?term=spr0892 spr0893 spr0893 spr0893 882279 882626 + hypothetical protein gene gene838 http://www.ncbi.nlm.nih.gov/gene/?term=spr0893 spr0894 spr0894 pfs pfs 882643 883335 + 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene839 http://www.ncbi.nlm.nih.gov/gene/?term=spr0894 spr0895 spr0895 spr0895 883412 883903 + hypothetical protein gene gene840 http://www.ncbi.nlm.nih.gov/gene/?term=spr0895 spr0896 spr0896 dnaQ dnaQ 883965 884591 + DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene841 http://www.ncbi.nlm.nih.gov/gene/?term=spr0896 spr0897 spr0897 spr0897 884594 886363 + hypothetical protein gene gene842 http://www.ncbi.nlm.nih.gov/gene/?term=spr0897 spr0898 spr0898 transposase_A transposase_A 886559 886974 + gene gene843 http://www.ncbi.nlm.nih.gov/gene/?term=spr0898 spr0900 spr0900 spr0900 887384 887584 + hypothetical protein gene gene844 http://www.ncbi.nlm.nih.gov/gene/?term=spr0900 spr0902 spr0902 spr0902 887626 888030 + hypothetical protein gene gene845 http://www.ncbi.nlm.nih.gov/gene/?term=spr0902 spr0903 spr0903 ccdA ccdA 888261 888968 + cytochrome c-type biogenesis protein gene gene846 http://www.ncbi.nlm.nih.gov/gene/?term=spr0903 spr0904 spr0904 spr0904 888961 889536 + hypothetical protein Similar to thiol:disulfide interchange protein gene gene847 http://www.ncbi.nlm.nih.gov/gene/?term=spr0904 spr0905 spr0905 yfnA yfnA 889898 891301 + cationic amino acid transporter gene gene848 http://www.ncbi.nlm.nih.gov/gene/?term=spr0905 spr0906 spr0906 lmb lmb 891426 892361 + adhesion lipoprotein gene gene849 http://www.ncbi.nlm.nih.gov/gene/?term=spr0906 spr0907 spr0907 phtD phtD 892369 894930 + pneumococcal histidine triad protein D gene gene850 http://www.ncbi.nlm.nih.gov/gene/?term=spr0907 spr0908 spr0908 phtE phtE 895140 898259 + pneumococcal histidine triad protein E gene gene851 http://www.ncbi.nlm.nih.gov/gene/?term=spr0908 spr0909 spr0909 spr0909 899089 899811 + gene gene852 http://www.ncbi.nlm.nih.gov/gene/?term=spr0909 spr0912 spr0912 spr0912 900059 900688 + hypothetical protein gene gene853 http://www.ncbi.nlm.nih.gov/gene/?term=spr0912 spr0913 spr0913 pepT pepT 900731 901951 - peptidase T catalyzes the release of the N-terminal amino acid from a tripeptide gene gene854 http://www.ncbi.nlm.nih.gov/gene/?term=spr0913 spr0914 spr0914 hemH hemH 902106 903200 + ferrochelatase gene gene855 http://www.ncbi.nlm.nih.gov/gene/?term=spr0914 spr0915 spr0915 mscL mscL 903242 903619 - large conductance mechanosensitive channel protein MscL gene gene856 http://www.ncbi.nlm.nih.gov/gene/?term=spr0915 spr0916 spr0916 mesH mesH 903701 904132 - GtrA family protein gene gene857 http://www.ncbi.nlm.nih.gov/gene/?term=spr0916 spr0917 spr0917 ccl ccl 904183 904764 + hypothetical protein gene gene858 http://www.ncbi.nlm.nih.gov/gene/?term=spr0917 spr0918 spr0918 asd asd 905279 906355 + aspartate-semialdehyde dehydrogenase catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde gene gene860 http://www.ncbi.nlm.nih.gov/gene/?term=spr0918 spr0919 spr0919 dapA dapA 906411 907346 + dihydrodipicolinate synthase catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis gene gene861 http://www.ncbi.nlm.nih.gov/gene/?term=spr0919 spr0920 spr0920 trmE trmE 907393 908766 - tRNA modification GTPase TrmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene862 http://www.ncbi.nlm.nih.gov/gene/?term=spr0920 spr0921 spr0921 xylH xylH 908903 909085 - 4-oxalocrotonate tautomerase 4-OT%3B member of subfamily 5%3B forms a dimer%3B the function in the Escherichia coli cell is unknown gene gene863 http://www.ncbi.nlm.nih.gov/gene/?term=spr0921 spr0922 spr0922 tdk tdk 909208 909807 + thymidine kinase catalyzes the formation of thymidine 5'-phosphate from thymidine gene gene864 http://www.ncbi.nlm.nih.gov/gene/?term=spr0922 spr0923 spr0923 bltD bltD 909797 910276 + spermine/spermidine acetyltransferase gene gene865 http://www.ncbi.nlm.nih.gov/gene/?term=spr0923 spr0924 spr0924 prfA prfA 910286 911365 + peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene866 http://www.ncbi.nlm.nih.gov/gene/?term=spr0924 spr0925 spr0925 hemK hemK 911365 912204 + HemK protein gene gene867 http://www.ncbi.nlm.nih.gov/gene/?term=spr0925 spr0926 spr0926 spr0926 912179 912790 + hypothetical protein gene gene868 http://www.ncbi.nlm.nih.gov/gene/?term=spr0926 spr0927 spr0927 spr0927 912753 913223 + hypothetical protein gene gene869 http://www.ncbi.nlm.nih.gov/gene/?term=spr0927 spr0928 spr0928 glyA glyA 913285 914541 + serine hydroxymethyltransferase catalyzes the reaction of glycine with 5%2C10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate gene gene870 http://www.ncbi.nlm.nih.gov/gene/?term=spr0928 spr0929 spr0929 spr0929 914516 915523 + hypothetical protein gene gene871 http://www.ncbi.nlm.nih.gov/gene/?term=spr0929 spr0930 spr0930 spr0930 915523 916137 + hypothetical protein RAS-related protein gene gene872 http://www.ncbi.nlm.nih.gov/gene/?term=spr0930 spr0931 spr0931 spr0931 916211 917185 + hypothetical protein gene gene873 http://www.ncbi.nlm.nih.gov/gene/?term=spr0931 spr0932 spr0932 spr0932 917259 918890 + hypothetical protein Similar to RNA methyltransferase gene gene874 http://www.ncbi.nlm.nih.gov/gene/?term=spr0932 spr0932a spr0932a spr0932a 919089 919382 + hypothetical protein gene gene875 http://www.ncbi.nlm.nih.gov/gene/?term=spr0932a spr0933 spr0933 spr0933 919628 919846 + hypothetical protein gene gene876 http://www.ncbi.nlm.nih.gov/gene/?term=spr0933 spr0934 spr0934 ABC-SBP ABC-SBP 920239 921264 + iron-compound ABC transporter substrate-binding protein gene gene877 http://www.ncbi.nlm.nih.gov/gene/?term=spr0934 spr0935 spr0935 ABC-MSP ABC-MSP 921242 922261 + iron-compound ABC transporter permease gene gene878 http://www.ncbi.nlm.nih.gov/gene/?term=spr0935 spr0936 spr0936 ABC-MSP ABC-MSP 922261 923268 + iron-compound ABC transporter permease gene gene879 http://www.ncbi.nlm.nih.gov/gene/?term=spr0936 spr0938 spr0938 ABC-NBD ABC-NBD 923268 924062 + iron-compound ABC transporter ATP-binding protein gene gene880 http://www.ncbi.nlm.nih.gov/gene/?term=spr0938 spr0939 spr0939 spr0939 924630 924839 + hypothetical protein gene gene881 http://www.ncbi.nlm.nih.gov/gene/?term=spr0939 spr0940 spr0940 spr0940 924964 925119 + hypothetical protein gene gene882 http://www.ncbi.nlm.nih.gov/gene/?term=spr0940 spr0941 spr0941 spr0941 925803 925964 + hypothetical protein gene gene883 http://www.ncbi.nlm.nih.gov/gene/?term=spr0941 spr0942 spr0942 ccrB ccrB 926056 927735 + hypothetical protein gene gene884 http://www.ncbi.nlm.nih.gov/gene/?term=spr0942 spr0943 spr0943 spr0943 927958 928569 + hypothetical protein gene gene885 http://www.ncbi.nlm.nih.gov/gene/?term=spr0943 spr0944 spr0944 spr0944 928891 929116 + gene gene886 http://www.ncbi.nlm.nih.gov/gene/?term=spr0944 spr0945 spr0945 spr0945 929141 929956 + hypothetical protein gene gene887 http://www.ncbi.nlm.nih.gov/gene/?term=spr0945 spr0946 spr0946 spr0946 929956 930810 + hydrolase hydrolase gene gene888 http://www.ncbi.nlm.nih.gov/gene/?term=spr0946 spr0947 spr0947 spr0947 930871 931806 + hypothetical protein gene gene889 http://www.ncbi.nlm.nih.gov/gene/?term=spr0947 spr0948 spr0948 nplT nplT 931945 933708 + neopullulanase gene gene890 http://www.ncbi.nlm.nih.gov/gene/?term=spr0948 spr0949 spr0949 spr0949 933794 934438 + gene gene891 http://www.ncbi.nlm.nih.gov/gene/?term=spr0949 spr0951 spr0951 spr0951 934826 935359 + transcriptional regulator gene gene892 http://www.ncbi.nlm.nih.gov/gene/?term=spr0951 spr0952 spr0952 spr0952 935359 936120 + hypothetical protein gene gene893 http://www.ncbi.nlm.nih.gov/gene/?term=spr0952 spr0953 spr0953 spr0953 936148 937304 + gene gene894 http://www.ncbi.nlm.nih.gov/gene/?term=spr0953 spr0955 spr0955 spr0955 938136 938495 + Tn5252%2C ORF 10 protein Hypothetical protein in TN5252 gene gene895 http://www.ncbi.nlm.nih.gov/gene/?term=spr0955 spr0956 spr0956 spr0956 938505 938834 + Tn5252%2C ORF 9 protein gene gene896 http://www.ncbi.nlm.nih.gov/gene/?term=spr0956 spr0957 spr0957 relaxase-truncation relaxase-truncation 938857 940062 + gene gene897 http://www.ncbi.nlm.nih.gov/gene/?term=spr0957 spr0959 spr0959 spr0959 940146 940742 + hypothetical protein gene gene898 http://www.ncbi.nlm.nih.gov/gene/?term=spr0959 spr0960 spr0960 mutR mutR 940787 941641 - positive transcriptional regulator MutR gene gene899 http://www.ncbi.nlm.nih.gov/gene/?term=spr0960 spr0961 spr0961 rffD rffD 941893 943188 + UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase gene gene900 http://www.ncbi.nlm.nih.gov/gene/?term=spr0961 spr0962 spr0962 spr0962 943148 943798 + hypothetical protein gene gene901 http://www.ncbi.nlm.nih.gov/gene/?term=spr0962 spr0963 spr0963 spr0963 943808 944590 + hypothetical protein gene gene902 http://www.ncbi.nlm.nih.gov/gene/?term=spr0963 spr0964 spr0964 spr0964 944613 946505 + hypothetical protein gene gene903 http://www.ncbi.nlm.nih.gov/gene/?term=spr0964 spr0965 spr0965 spr0965 946534 947640 + hypothetical protein gene gene904 http://www.ncbi.nlm.nih.gov/gene/?term=spr0965 spr0966 spr0966 spr0966 947648 948958 + hypothetical protein Probable acid-CoA ligase gene gene905 http://www.ncbi.nlm.nih.gov/gene/?term=spr0966 spr0967 spr0967 spr0967 948960 950183 + hypothetical protein gene gene906 http://www.ncbi.nlm.nih.gov/gene/?term=spr0967 spr0968 spr0968 spr0968 950173 951123 + hypothetical protein gene gene907 http://www.ncbi.nlm.nih.gov/gene/?term=spr0968 spr0969 spr0969 nikS nikS 951138 952337 + nikkomycin biosynthesis protein%2C carboxylase gene gene908 http://www.ncbi.nlm.nih.gov/gene/?term=spr0969 spr0970 spr0970 spr0970 952356 953000 + hypothetical protein Probable acetyltransferase gene gene909 http://www.ncbi.nlm.nih.gov/gene/?term=spr0970 spr0971 spr0971 mefE mefE 953383 954594 + macolide ABC transporter permease gene gene910 http://www.ncbi.nlm.nih.gov/gene/?term=spr0971 spr0972 spr0972 spr0972 955253 955474 + hypothetical protein repressor protein gene gene911 http://www.ncbi.nlm.nih.gov/gene/?term=spr0972 spr0973 spr0973 ftsW ftsW 956376 957605 + cell division protein FtsW gene gene912 http://www.ncbi.nlm.nih.gov/gene/?term=spr0973 spr0974 spr0974 ppc ppc 957625 960321 + phosphoenolpyruvate carboxylase catalyzes the formation of oxaloacetate from phosphoenolpyruvate gene gene913 http://www.ncbi.nlm.nih.gov/gene/?term=spr0974 spr0975 spr0975 ABC-SBP ABC-SBP 960704 961738 + hypothetical protein gene gene914 http://www.ncbi.nlm.nih.gov/gene/?term=spr0975 spr0976 spr0976 ABC-MSP ABC-MSP 961807 962673 + ABC transporter permease gene gene915 http://www.ncbi.nlm.nih.gov/gene/?term=spr0976 spr0977 spr0977 ABC-NBD ABC-NBD 962670 963428 + ABC transporter ATP-binding protein gene gene916 http://www.ncbi.nlm.nih.gov/gene/?term=spr0977 spr0978 spr0978 dnaG dnaG 963503 965278 + DNA primase synthesizes RNA primers at the replication forks gene gene917 http://www.ncbi.nlm.nih.gov/gene/?term=spr0978 spr0979 spr0979 rpoD rpoD 965281 966390 + RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B primary sigma factor of bacterium gene gene918 http://www.ncbi.nlm.nih.gov/gene/?term=spr0979 spr0980 spr0980 spr0980 966371 966733 + hypothetical protein gene gene919 http://www.ncbi.nlm.nih.gov/gene/?term=spr0980 spr0981 spr0981 cpoA cpoA 966767 967891 + glycosyl transferase CpoA gene gene920 http://www.ncbi.nlm.nih.gov/gene/?term=spr0981 spr0982 spr0982 spr0982 967907 969232 + glycosyl transferase Probable hexosyltransferase gene gene921 http://www.ncbi.nlm.nih.gov/gene/?term=spr0982 spr0983 spr0983 spr0983 969263 969439 + hypothetical protein gene gene922 http://www.ncbi.nlm.nih.gov/gene/?term=spr0983 spr0984 spr0984 obgE obgE 969702 971006 + GTPase ObgE essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene923 http://www.ncbi.nlm.nih.gov/gene/?term=spr0984 spr0985 spr0985 spr0985 971016 971174 + hypothetical protein gene gene924 http://www.ncbi.nlm.nih.gov/gene/?term=spr0985 spr0988 spr0988 IS1167 IS1167 972009 972563 - transposase gene gene925 http://www.ncbi.nlm.nih.gov/gene/?term=spr0988 spr0989 spr0989 murZ murZ 973796 975055 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation%3B gram-positive bacteria have 2 copies of MurA which are active gene gene926 http://www.ncbi.nlm.nih.gov/gene/?term=spr0989 spr0990 spr0990 spr0990 975065 975622 + hypothetical protein Similar to alanine acetyl transferase gene gene927 http://www.ncbi.nlm.nih.gov/gene/?term=spr0990 spr0991 spr0991 spr0991 975615 976892 + hypothetical protein gene gene928 http://www.ncbi.nlm.nih.gov/gene/?term=spr0991 spr0992 spr0992 map map 976908 977768 + methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides gene gene929 http://www.ncbi.nlm.nih.gov/gene/?term=spr0992 spr0993 spr0993 spr0993 977840 978547 + hypothetical protein gene gene930 http://www.ncbi.nlm.nih.gov/gene/?term=spr0993 spr0994 spr0994 IS1381 IS1381 978562 978951 + tranposase gene gene931 http://www.ncbi.nlm.nih.gov/gene/?term=spr0994 spr0995 spr0995 pcrA pcrA 979142 981433 + ATP-dependent DNA helicase PcrA gene gene932 http://www.ncbi.nlm.nih.gov/gene/?term=spr0995 spr0996 spr0996 radC radC 981461 982156 + DNA repair protein RadC Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase gene gene933 http://www.ncbi.nlm.nih.gov/gene/?term=spr0996 spr0997 spr0997 spr0997 982153 982842 - hypothetical protein Probable amidotransferase gene gene934 http://www.ncbi.nlm.nih.gov/gene/?term=spr0997 spr0998 spr0998 spr0998 982860 983501 - redox-sensing transcriptional repressor Rex modulates transcription in response to the NADH/NAD(+) redox state gene gene935 http://www.ncbi.nlm.nih.gov/gene/?term=spr0998 spr0999 spr0999 spr0999 983584 983835 - hypothetical protein gene gene936 http://www.ncbi.nlm.nih.gov/gene/?term=spr0999 spr1000 spr1000 spr1000 983807 984154 - hypothetical protein gene gene937 http://www.ncbi.nlm.nih.gov/gene/?term=spr1000 spr1001 spr1001 nifS nifS 984159 985274 - pyridoxal-phosphate dependent aminotransferase gene gene938 http://www.ncbi.nlm.nih.gov/gene/?term=spr1001 spr1002 spr1002 prs prs 985284 986243 - ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene939 http://www.ncbi.nlm.nih.gov/gene/?term=spr1002 spr1003 spr1003 spr1003 986356 986925 - hypothetical protein gene gene940 http://www.ncbi.nlm.nih.gov/gene/?term=spr1003 spr1004 spr1004 spr1004 987053 987724 + GTP pyrophosphokinase gene gene941 http://www.ncbi.nlm.nih.gov/gene/?term=spr1004 spr1005 spr1005 ppnK ppnK 987696 988526 + inorganic polyphosphate/ATP-NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene942 http://www.ncbi.nlm.nih.gov/gene/?term=spr1005 spr1006 spr1006 rluD rluD 988523 989419 + 23S rRNA pseudouridine synthase gene gene943 http://www.ncbi.nlm.nih.gov/gene/?term=spr1006 spr1007 spr1007 eutD eutD 989463 990437 + phosphotransacetylase in Salmonella this enzyme is required for ethanolamine catabolism%3B has higher affinity for CoA than Pta gene gene944 http://www.ncbi.nlm.nih.gov/gene/?term=spr1007 spr1009 spr1009 IS1167 IS1167 991498 992016 - transposase gene gene945 http://www.ncbi.nlm.nih.gov/gene/?term=spr1009 spr1010 spr1010 spr1010 992198 992497 - hypothetical protein gene gene946 http://www.ncbi.nlm.nih.gov/gene/?term=spr1010 spr1011 spr1011 spr1011 992899 993603 + hypothetical protein gene gene947 http://www.ncbi.nlm.nih.gov/gene/?term=spr1011 spr1012 spr1012 rplU rplU 993785 994099 + 50S ribosomal protein L21 gene gene948 http://www.ncbi.nlm.nih.gov/gene/?term=spr1012 spr1013 spr1013 spr1013 994115 994459 + hypothetical protein gene gene949 http://www.ncbi.nlm.nih.gov/gene/?term=spr1013 spr1014 spr1014 rpmA rpmA 994500 994769 + 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene950 http://www.ncbi.nlm.nih.gov/gene/?term=spr1014 spr1017 spr1017 mreA mreA 995722 996639 + bifunctional riboflavin kinase/FMN adenylyltransferase catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN%3B in Bacillus the ribC gene has both flavokinase and FAD synthetase activities gene gene951 http://www.ncbi.nlm.nih.gov/gene/?term=spr1017 spr1018 spr1018 spr1018 996732 997580 - hypothetical protein gene gene952 http://www.ncbi.nlm.nih.gov/gene/?term=spr1018 spr1019 spr1019 spr1019 997722 998561 + hypothetical protein Similar to Bacillus subtilis DegV protein gene gene953 http://www.ncbi.nlm.nih.gov/gene/?term=spr1019 spr1020 spr1020 hlpA hlpA 998667 998942 + DNA-binding protein HU gene gene954 http://www.ncbi.nlm.nih.gov/gene/?term=spr1020 spr1021 spr1021 ABC-NBD ABC-NBD 999368 1001269 + ABC transporter ATP-binding protein gene gene955 http://www.ncbi.nlm.nih.gov/gene/?term=spr1021 spr1022 spr1022 rggD rggD 1001242 1002135 + transcriptional regulator MutR gene gene956 http://www.ncbi.nlm.nih.gov/gene/?term=spr1022 spr1023 spr1023 ABC-MSP ABC-MSP 1002215 1003393 + macrolide ABC transporter permease gene gene957 http://www.ncbi.nlm.nih.gov/gene/?term=spr1023 spr1024 spr1024 ligA ligA 1003486 1005444 + NAD-dependent DNA ligase LigA this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene958 http://www.ncbi.nlm.nih.gov/gene/?term=spr1024 spr1025 spr1025 pulI pulI 1005556 1007835 + thermostable pullulanase gene gene959 http://www.ncbi.nlm.nih.gov/gene/?term=spr1025 spr1028 spr1028 gapN gapN 1008379 1009803 + glyceraldehyde-3-phosphate dehydrogenase gene gene960 http://www.ncbi.nlm.nih.gov/gene/?term=spr1028 spr1029 spr1029 glgB glgB 1010268 1012196 + glycogen branching protein catalyzes the transfer of a segment of a 1%2C4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain gene gene961 http://www.ncbi.nlm.nih.gov/gene/?term=spr1029 spr1030 spr1030 glgC glgC 1012186 1013328 + glucose-1-phosphate adenylyltransferase catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate gene gene962 http://www.ncbi.nlm.nih.gov/gene/?term=spr1030 spr1031 spr1031 glgD glgD 1013318 1014457 + required for glycogen biosynthesis gene gene963 http://www.ncbi.nlm.nih.gov/gene/?term=spr1031 spr1032 spr1032 glgA glgA 1014454 1015887 + glycogen synthase catalyzes the formation of alpha-1%2C4-glucan chains from ADP-glucose gene gene964 http://www.ncbi.nlm.nih.gov/gene/?term=spr1032 spr1033 spr1033 serB-truncation serB-truncation 1015946 1016591 + gene gene965 http://www.ncbi.nlm.nih.gov/gene/?term=spr1033 spr1034 spr1034 glxK glxK 1016588 1017715 + glycerate kinase gene gene966 http://www.ncbi.nlm.nih.gov/gene/?term=spr1034 spr1035 spr1035 spr1035 1017712 1018158 - hypothetical protein gene gene967 http://www.ncbi.nlm.nih.gov/gene/?term=spr1035 spr1036 spr1036 eno eno 1018322 1019626 + phosphopyruvate hydratase enolase%3B catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene968 http://www.ncbi.nlm.nih.gov/gene/?term=spr1036 spr1038 spr1038 transposase_A transposase_A 1020607 1020975 - transposase gene gene969 http://www.ncbi.nlm.nih.gov/gene/?term=spr1038 spr1039 spr1039 rexB rexB 1021482 1024757 + second subunit of major exonuclease gene gene970 http://www.ncbi.nlm.nih.gov/gene/?term=spr1039 spr1040 spr1040 rexA rexA 1024754 1028404 + exonuclease RexA gene gene971 http://www.ncbi.nlm.nih.gov/gene/?term=spr1040 spr1041 spr1041 spr1041 1028574 1029752 + hypothetical protein gene gene972 http://www.ncbi.nlm.nih.gov/gene/?term=spr1041 spr1042 spr1042 iga iga 1029961 1035852 + immunoglobulin A1 protease gene gene973 http://www.ncbi.nlm.nih.gov/gene/?term=spr1042 spr1043 spr1043 rbgA rbgA 1036311 1037162 + ribosomal biogenesis GTPase essential GTPase%3B functions in ribosome assembly%3B binds a unique part of the 23S rRNA%3B interacts with ribosomal protein L25(Ctc) gene gene974 http://www.ncbi.nlm.nih.gov/gene/?term=spr1043 spr1044 spr1044 rnhB rnhB 1037149 1037928 + ribonuclease HII RNH2%3B RNase HII%3B binds manganese%3B endonuclease which specifically degrades the RNA of RNA-DNA hybrids gene gene975 http://www.ncbi.nlm.nih.gov/gene/?term=spr1044 spr1045 spr1045 spr1045 1037929 1039494 + voltage-gated chloride channel family protein channel transporter gene gene976 http://www.ncbi.nlm.nih.gov/gene/?term=spr1045 spr1046 spr1046 xerS xerS 1040078 1041148 + site-specific tyrosine recombinase XerS site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerS gene gene977 http://www.ncbi.nlm.nih.gov/gene/?term=spr1046 spr1047 spr1047 lplA lplA 1041221 1042210 - lipoate-protein ligase gene gene978 http://www.ncbi.nlm.nih.gov/gene/?term=spr1047 spr1048 spr1048 acoL acoL 1042274 1043977 - dihydrolipoamide dehydrogenase gene gene979 http://www.ncbi.nlm.nih.gov/gene/?term=spr1048 spr1049 spr1049 acoC acoC 1044023 1045066 - dihydrolipoamide acetyltransferase unlike PdhC proteins from other organisms%2C some Mycoplasma lack an N-terminal lipoyl domain%3B in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain gene gene980 http://www.ncbi.nlm.nih.gov/gene/?term=spr1049 spr1050 spr1050 acoB acoB 1045284 1046276 - acetoin dehydrogenase%2C E1 component subunit beta gene gene981 http://www.ncbi.nlm.nih.gov/gene/?term=spr1050 spr1051 spr1051 acoA acoA 1046292 1047260 - TPP-dependent acetoin dehydrogenase subunit alpha gene gene982 http://www.ncbi.nlm.nih.gov/gene/?term=spr1051 spr1052 spr1052 spr1052 1047414 1048775 - MATE efflux family protein gene gene983 http://www.ncbi.nlm.nih.gov/gene/?term=spr1052 spr1053 spr1053 pyrC pyrC 1049060 1050328 - dihydroorotase catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis gene gene984 http://www.ncbi.nlm.nih.gov/gene/?term=spr1053 spr1054 spr1054 mutX mutX 1050341 1050805 - 8-oxodGTP nucleoside triphosphatase gene gene985 http://www.ncbi.nlm.nih.gov/gene/?term=spr1054 spr1055 spr1055 ung ung 1050815 1051483 - uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene986 http://www.ncbi.nlm.nih.gov/gene/?term=spr1055 spr1056 spr1056 spr1056 1051604 1052251 - hypothetical protein gene gene987 http://www.ncbi.nlm.nih.gov/gene/?term=spr1056 spr1057 spr1057 spr1057 1052265 1052978 - hypothetical protein gene gene988 http://www.ncbi.nlm.nih.gov/gene/?term=spr1057 spr1058 spr1058 spr1058 1053436 1053816 - gene gene989 http://www.ncbi.nlm.nih.gov/gene/?term=spr1058 spr1060 spr1060 phpA phpA 1054238 1056805 - histidine motif-containing protein gene gene990 http://www.ncbi.nlm.nih.gov/gene/?term=spr1060 spr1061 spr1061 phtA phtA 1056930 1059416 - pneumococcal histidine triad protein A gene gene991 http://www.ncbi.nlm.nih.gov/gene/?term=spr1061 spr1062 spr1062 ptsI ptsI 1059635 1061368 - phosphoenolpyruvate-protein phosphotransferase gene gene992 http://www.ncbi.nlm.nih.gov/gene/?term=spr1062 spr1063 spr1063 ptsH ptsH 1061374 1061637 - phosphocarrier protein HPr gene gene993 http://www.ncbi.nlm.nih.gov/gene/?term=spr1063 spr1064 spr1064 nrdH nrdH 1061970 1062206 + glutaredoxin-like protein gene gene994 http://www.ncbi.nlm.nih.gov/gene/?term=spr1064 spr1065 spr1065 nrdE nrdE 1062287 1064446 + ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene995 http://www.ncbi.nlm.nih.gov/gene/?term=spr1065 spr1066 spr1066 nrdF nrdF 1064634 1065596 + ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE gene gene996 http://www.ncbi.nlm.nih.gov/gene/?term=spr1066 spr1067 spr1067 lacR lacR 1065778 1066539 + lactose PTS system repressor gene gene997 http://www.ncbi.nlm.nih.gov/gene/?term=spr1067 spr1069 spr1069 lacG lacG 1067037 1068443 - 6-phospho-beta-galactosidase catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside gene gene998 http://www.ncbi.nlm.nih.gov/gene/?term=spr1069 spr1070 spr1070 lacE lacE 1068652 1070343 - PTS system lactose-specific transporter subunit IIBC gene gene999 http://www.ncbi.nlm.nih.gov/gene/?term=spr1070 spr1071 spr1071 lacF lacF 1070343 1070660 - PTS system lactose-specific transporter subunit IIA gene gene1000 http://www.ncbi.nlm.nih.gov/gene/?term=spr1071 spr1072 spr1072 lacT lacT 1070696 1071532 - transcription antiterminator LacT gene gene1001 http://www.ncbi.nlm.nih.gov/gene/?term=spr1072 spr1073 spr1073 lacD lacD 1071766 1072746 - tagatose 1%2C6-diphosphate aldolase catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1%2C6-bisphosphate%3B in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase%2C encoded by lacD1 and lacD2%3B expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources gene gene1002 http://www.ncbi.nlm.nih.gov/gene/?term=spr1073 spr1074 spr1074 lacC lacC 1072748 1073677 - tagatose-6-phosphate kinase catalyzes the formation of tagatose 1%2C6-bisphosphate from tagatose 6-phosphate and ATP gene gene1003 http://www.ncbi.nlm.nih.gov/gene/?term=spr1074 spr1075 spr1075 lacB lacB 1073688 1074203 - galactose-6-phosphate isomerase subunit LacB catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate gene gene1004 http://www.ncbi.nlm.nih.gov/gene/?term=spr1075 spr1076 spr1076 lacA lacA 1074234 1074659 - galactose-6-phosphate isomerase subunit LacA catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate%3B tagatose pathway for galactose utilization gene gene1005 http://www.ncbi.nlm.nih.gov/gene/?term=spr1076 spr1078 spr1078 spr1078 1075330 1075728 - transposase gene gene1006 http://www.ncbi.nlm.nih.gov/gene/?term=spr1078 spr1079 spr1079 spr1079 1075659 1076180 - hypothetical protein gene gene1007 http://www.ncbi.nlm.nih.gov/gene/?term=spr1079 spr1079a spr1079a spr1079a 1077136 1077288 + hypothetical protein gene gene1010 http://www.ncbi.nlm.nih.gov/gene/?term=spr1079a spr1080 spr1080 spr1080 1076140 1076442 - hypothetical protein gene gene1008 http://www.ncbi.nlm.nih.gov/gene/?term=spr1080 spr1081 spr1081 spr1081 1076480 1076752 - hypothetical protein gene gene1009 http://www.ncbi.nlm.nih.gov/gene/?term=spr1081 spr1082 spr1082 lepA lepA 1077369 1079192 - GTP-binding protein LepA binds to the ribosome on the universally-conserved alpha-sarcin loop gene gene1011 http://www.ncbi.nlm.nih.gov/gene/?term=spr1082 spr1083 spr1083 pphA pphA 1079271 1079999 - serine/threonine protein phosphatase gene gene1012 http://www.ncbi.nlm.nih.gov/gene/?term=spr1083 spr1084 spr1084 recN recN 1080001 1081668 - DNA repair protein RecN gene gene1013 http://www.ncbi.nlm.nih.gov/gene/?term=spr1084 spr1085 spr1085 ahrC ahrC 1081675 1082106 - arginine metabolism transcriptional regulator gene gene1014 http://www.ncbi.nlm.nih.gov/gene/?term=spr1085 spr1086 spr1086 spr1086 1082099 1082914 - hypothetical protein Hemolysin-like protein gene gene1015 http://www.ncbi.nlm.nih.gov/gene/?term=spr1086 spr1087 spr1087 ispA ispA 1082907 1083782 - geranyltranstransferase gene gene1016 http://www.ncbi.nlm.nih.gov/gene/?term=spr1087 spr1088 spr1088 xseB xseB 1083779 1083991 - exodeoxyribonuclease VII small subunit catalyzes the bidirectional exonucleolytic cleavage of DNA gene gene1017 http://www.ncbi.nlm.nih.gov/gene/?term=spr1088 spr1089 spr1089 xseA xseA 1083969 1085315 - exodeoxyribonuclease VII large subunit bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides gene gene1018 http://www.ncbi.nlm.nih.gov/gene/?term=spr1089 spr1090 spr1090 udK udK 1085437 1086075 - uridine kinase functions in pyrimidine salvage%3B pyrimidine ribonucleoside kinase%3B phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor gene gene1019 http://www.ncbi.nlm.nih.gov/gene/?term=spr1090 spr1091 spr1091 spr1091 1086183 1086485 - hypothetical protein gene gene1020 http://www.ncbi.nlm.nih.gov/gene/?term=spr1091 spr1092 spr1092 truB truB 1086726 1087604 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene1021 http://www.ncbi.nlm.nih.gov/gene/?term=spr1092 spr1093 spr1093 spr1093 1087705 1090890 - hypothetical protein gene gene1022 http://www.ncbi.nlm.nih.gov/gene/?term=spr1093 spr1094 spr1094 spr1094 1090902 1092176 - hypothetical protein gene gene1023 http://www.ncbi.nlm.nih.gov/gene/?term=spr1094 spr1095 spr1095 metY-truncation metY-truncation 1092272 1093531 - gene gene1024 http://www.ncbi.nlm.nih.gov/gene/?term=spr1095 spr1097 spr1097 nirC nirC 1093679 1094476 - formate/nitrate transporter gene gene1025 http://www.ncbi.nlm.nih.gov/gene/?term=spr1097 spr1098 spr1098 srtA srtA 1094720 1095463 - sortase proposed to perform the peptide cleavage and the transpeptidation during the process of anchoring proteins to Gram-positive bacterial cell walls gene gene1026 http://www.ncbi.nlm.nih.gov/gene/?term=spr1098 spr1099 spr1099 gyrA gyrA 1095463 1097931 - DNA gyrase subunit A negatively supercoils closed circular double-stranded DNA gene gene1027 http://www.ncbi.nlm.nih.gov/gene/?term=spr1099 spr1100 spr1100 ldh ldh 1098125 1099111 + L-lactate dehydrogenase Converts (S)-lactate and NAD(+) to pyruvate and NADH gene gene1028 http://www.ncbi.nlm.nih.gov/gene/?term=spr1100 spr1101 spr1101 spnII-interrupted-C spnII-interrupted-C 1099497 1102751 - type II restriction endonuclease gene gene1029 http://www.ncbi.nlm.nih.gov/gene/?term=spr1101 spr1102 spr1102 spnII-interrupted-N spnII-interrupted-N 1102916 1104793 - type II restriction endonuclease gene gene1030 http://www.ncbi.nlm.nih.gov/gene/?term=spr1102 spr1103 spr1103 spr1103 1104862 1105125 - hypothetical protein gene gene1031 http://www.ncbi.nlm.nih.gov/gene/?term=spr1103 spr1104 spr1104 spr1104 1105118 1105420 - hypothetical protein gene gene1032 http://www.ncbi.nlm.nih.gov/gene/?term=spr1104 spr1105 spr1105 vicX vicX 1105451 1106260 - metal-dependent hydrolase gene gene1033 http://www.ncbi.nlm.nih.gov/gene/?term=spr1105 spr1106 spr1106 hk02 hk02 1106262 1107611 - sensory box sensor histidine kinase gene gene1034 http://www.ncbi.nlm.nih.gov/gene/?term=spr1106 spr1107 spr1107 rr02 rr02 1107604 1108359 - DNA-binding response regulator gene gene1035 http://www.ncbi.nlm.nih.gov/gene/?term=spr1107 spr1108 spr1108 mutY mutY 1108363 1109538 - A/G-specific adenine glycosylase gene gene1036 http://www.ncbi.nlm.nih.gov/gene/?term=spr1108 spr1109 spr1109 fhs fhs 1109867 1111537 - formate--tetrahydrofolate ligase catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate gene gene1037 http://www.ncbi.nlm.nih.gov/gene/?term=spr1109 spr1110 spr1110 dfp-C-terminus dfp-C-terminus 1111752 1112456 + phosphopantothenate--cysteine ligase gene gene1038 http://www.ncbi.nlm.nih.gov/gene/?term=spr1110 spr1111 spr1111 dfp-N-terminus dfp-N-terminus 1112468 1113019 + phosphopantothenoylcysteine decarboxylase decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine. gene gene1039 http://www.ncbi.nlm.nih.gov/gene/?term=spr1111 spr1112 spr1112 spr1112 1113003 1113566 + hypothetical protein Probable membrane protein gene gene1040 http://www.ncbi.nlm.nih.gov/gene/?term=spr1112 spr1113 spr1113 spr1113 1113794 1114375 + hypothetical protein gene gene1041 http://www.ncbi.nlm.nih.gov/gene/?term=spr1113 spr1114 spr1114 spr1114 1114387 1114902 + hypothetical protein Probable transcriptional regulator gene gene1042 http://www.ncbi.nlm.nih.gov/gene/?term=spr1114 spr1115 spr1115 spr1115 1114899 1115366 - hypothetical protein MutT-like protein gene gene1043 http://www.ncbi.nlm.nih.gov/gene/?term=spr1115 spr1116 spr1116 spr1116 1115440 1115928 - hypothetical protein Acetyltransferase (GNAT) family gene gene1044 http://www.ncbi.nlm.nih.gov/gene/?term=spr1116 spr1117 spr1117 spr1117 1115894 1116457 - hypothetical protein Probable acetyltransferase gene gene1045 http://www.ncbi.nlm.nih.gov/gene/?term=spr1117 spr1118 spr1118 uvrB uvrB 1116467 1118455 - excinuclease ABC subunit B The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion gene gene1046 http://www.ncbi.nlm.nih.gov/gene/?term=spr1118 spr1119 spr1119 spr1119 1118532 1119485 - hypothetical protein transmembrane protein gene gene1047 http://www.ncbi.nlm.nih.gov/gene/?term=spr1119 spr1120 spr1120 glnP glnP 1119658 1121823 + amino acid ABC transporter substrate-binding protein gene gene1048 http://www.ncbi.nlm.nih.gov/gene/?term=spr1120 spr1121 spr1121 glnQ glnQ 1121823 1122563 + amino acid ABC transporter ATP-binding protein gene gene1049 http://www.ncbi.nlm.nih.gov/gene/?term=spr1121 spr1122 spr1122 zwf zwf 1122712 1124199 + glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene1050 http://www.ncbi.nlm.nih.gov/gene/?term=spr1122 spr1123 spr1123 ftsY ftsY 1124245 1125522 - signal recognition particle-docking protein FtsY gene gene1051 http://www.ncbi.nlm.nih.gov/gene/?term=spr1123 spr1124 spr1124 spr1124 1125526 1126344 - Cof family protein gene gene1052 http://www.ncbi.nlm.nih.gov/gene/?term=spr1124 spr1125 spr1125 spr1125 1126344 1127138 - Cof family protein gene gene1053 http://www.ncbi.nlm.nih.gov/gene/?term=spr1125 spr1126 spr1126 smc smc 1127135 1130674 - chromosome condensation and segregation SMC protein gene gene1054 http://www.ncbi.nlm.nih.gov/gene/?term=spr1126 spr1127 spr1127 rnc rnc 1130665 1131363 - ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene1055 http://www.ncbi.nlm.nih.gov/gene/?term=spr1127 spr1128 spr1128 guaC guaC 1131681 1132667 - guanosine 5'-monophosphate oxidoreductase gene gene1057 http://www.ncbi.nlm.nih.gov/gene/?term=spr1128 spr1129 spr1129 spr1129 1132842 1134185 - hypothetical protein gene gene1058 http://www.ncbi.nlm.nih.gov/gene/?term=spr1129 spr1130 spr1130 spr1130 1134145 1136079 - endonuclease Probable endonuclease gene gene1059 http://www.ncbi.nlm.nih.gov/gene/?term=spr1130 spr1131 spr1131 spr1131 1136240 1136410 - hypothetical protein gene gene1060 http://www.ncbi.nlm.nih.gov/gene/?term=spr1131 spr1132 spr1132 spr1132 1136391 1136564 - hypothetical protein gene gene1061 http://www.ncbi.nlm.nih.gov/gene/?term=spr1132 spr1134 spr1134 spr1134 1137389 1137658 - hypothetical protein gene gene1062 http://www.ncbi.nlm.nih.gov/gene/?term=spr1134 spr1135 spr1135 leuB leuB 1137655 1138692 - 3-isopropylmalate dehydrogenase catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis gene gene1063 http://www.ncbi.nlm.nih.gov/gene/?term=spr1135 spr1136 spr1136 leuA-truncation leuA-truncation 1138704 1139798 - gene gene1064 http://www.ncbi.nlm.nih.gov/gene/?term=spr1136 spr1138 spr1138 spr1138 1139817 1140473 - hypothetical protein gene gene1065 http://www.ncbi.nlm.nih.gov/gene/?term=spr1138 spr1139 spr1139 cutC cutC 1140517 1141149 - copper homeostasis protein CutC gene gene1066 http://www.ncbi.nlm.nih.gov/gene/?term=spr1139 spr1140 spr1140 spr1140 1141242 1141601 - hypothetical protein gene gene1067 http://www.ncbi.nlm.nih.gov/gene/?term=spr1140 spr1141 spr1141 topA topA 1141707 1143812 - DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene1068 http://www.ncbi.nlm.nih.gov/gene/?term=spr1141 spr1142 spr1142 spr1142 1143961 1145004 - hypothetical protein gene gene1069 http://www.ncbi.nlm.nih.gov/gene/?term=spr1142 spr1144 spr1144 smf smf 1145894 1146754 - DNA processing protein DprA Also known as Competence induced loci B%2C CilB gene gene1070 http://www.ncbi.nlm.nih.gov/gene/?term=spr1144 spr1145 spr1145 licC licC 1146838 1147527 - hypothetical protein gene gene1071 http://www.ncbi.nlm.nih.gov/gene/?term=spr1145 spr1146 spr1146 licB licB 1147539 1148429 - hypothetical protein gene gene1072 http://www.ncbi.nlm.nih.gov/gene/?term=spr1146 spr1147 spr1147 pck pck 1148407 1149276 - choline kinase gene gene1073 http://www.ncbi.nlm.nih.gov/gene/?term=spr1147 spr1148 spr1148 spr1148 1149293 1150333 - zinc-containing alcohol dehydrogenase Probable oxidoreductase gene gene1074 http://www.ncbi.nlm.nih.gov/gene/?term=spr1148 spr1149 spr1149 ispD ispD 1150320 1151027 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4-diphosphocytidyl-2C-methyl-D-erythritol synthase%3B MEP cytidylyltransferase%3B MCT%3B catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate%3B involved in isoprenoid and isopentenyl-PP biosynthesis%3B forms homodimers gene gene1075 http://www.ncbi.nlm.nih.gov/gene/?term=spr1149 spr1150 spr1150 spr1150 1151363 1152850 + polysaccharide biosynthesis protein Probable oligosaccharide repeat unit transporter gene gene1076 http://www.ncbi.nlm.nih.gov/gene/?term=spr1150 spr1151 spr1151 licD1 licD1 1152860 1153663 + required for phosphorylcholine incorporation in teichoic and lipoteichoic acids gene gene1077 http://www.ncbi.nlm.nih.gov/gene/?term=spr1151 spr1152 spr1152 licD2 licD2 1153665 1154474 + licD protein Required for phosphorylcholine incorporation in teichoic and lipoteichoic acids gene gene1078 http://www.ncbi.nlm.nih.gov/gene/?term=spr1152 spr1153 spr1153 carB carB 1154749 1157925 - carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene1079 http://www.ncbi.nlm.nih.gov/gene/?term=spr1153 spr1154 spr1154 carA carA 1158238 1159317 - carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene1080 http://www.ncbi.nlm.nih.gov/gene/?term=spr1154 spr1155 spr1155 pyrB pyrB 1159367 1160290 - aspartate carbamoyltransferase catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis gene gene1081 http://www.ncbi.nlm.nih.gov/gene/?term=spr1155 spr1156 spr1156 pyrR pyrR 1160309 1160830 - bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes%2C also has been shown to have uracil phosphoribosyltransferase activity gene gene1082 http://www.ncbi.nlm.nih.gov/gene/?term=spr1156 spr1157 spr1157 nth nth 1161041 1161670 - endonuclease III gene gene1083 http://www.ncbi.nlm.nih.gov/gene/?term=spr1157 spr1158 spr1158 spr1158 1161670 1162212 - hypothetical protein gene gene1084 http://www.ncbi.nlm.nih.gov/gene/?term=spr1158 spr1159 spr1159 spr1159 1162382 1162698 + gene gene1085 http://www.ncbi.nlm.nih.gov/gene/?term=spr1159 spr1161 spr1161 ABC-NBD ABC-NBD 1162971 1164497 + ABC transporter ATP-binding protein gene gene1086 http://www.ncbi.nlm.nih.gov/gene/?term=spr1161 spr1162 spr1162 htpX htpX 1164646 1165554 - heat shock protein HtpX metalloprotease gene gene1087 http://www.ncbi.nlm.nih.gov/gene/?term=spr1162 spr1163 spr1163 lemA lemA 1165547 1166107 - cytoplasmic membrane protein gene gene1088 http://www.ncbi.nlm.nih.gov/gene/?term=spr1163 spr1164 spr1164 gidB gidB 1166177 1166914 + 16S rRNA methyltransferase GidB glucose-inhibited division protein B%3B SAM-dependent methyltransferase%3B methylates the N7 position of guanosine in position 527 of 16S rRNA gene gene1089 http://www.ncbi.nlm.nih.gov/gene/?term=spr1164 spr1165 spr1165 pyrP pyrP 1167230 1168549 + uracil permease gene gene1090 http://www.ncbi.nlm.nih.gov/gene/?term=spr1165 spr1166 spr1166 ffh ffh 1168744 1170315 - signal recognition particle protein gene gene1091 http://www.ncbi.nlm.nih.gov/gene/?term=spr1166 spr1167 spr1167 spr1167 1170327 1170659 - DNA-binding protein gene gene1092 http://www.ncbi.nlm.nih.gov/gene/?term=spr1167 spr1168 spr1168 spr1168 1170750 1171127 - hypothetical protein gene gene1093 http://www.ncbi.nlm.nih.gov/gene/?term=spr1168 spr1169 spr1169 spr1169 1171103 1172503 + hypothetical protein gene gene1094 http://www.ncbi.nlm.nih.gov/gene/?term=spr1169 spr1170 spr1170 spr1170 1172516 1173322 + Cof family protein gene gene1095 http://www.ncbi.nlm.nih.gov/gene/?term=spr1170 spr1171 spr1171 rplS rplS 1173490 1173837 - 50S ribosomal protein L19 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site gene gene1097 http://www.ncbi.nlm.nih.gov/gene/?term=spr1171 spr1172 spr1172 crcB crcB 1173956 1174285 - camphor resistance protein CrcB may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene1098 http://www.ncbi.nlm.nih.gov/gene/?term=spr1172 spr1173 spr1173 crcB crcB 1174279 1174653 - camphor resistance protein CrcB may be involved in chromosome condensation%3B overexpression in Escherichia coli protects against decondensation by camphor%3B overexpressing the protein results in an increase in supercoiling gene gene1099 http://www.ncbi.nlm.nih.gov/gene/?term=spr1173 spr1174 spr1174 spr1174 1174650 1174916 - hypothetical protein gene gene1100 http://www.ncbi.nlm.nih.gov/gene/?term=spr1174 spr1175 spr1175 flaV flaV 1175032 1175475 - flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene1101 http://www.ncbi.nlm.nih.gov/gene/?term=spr1175 spr1176 spr1176 spr1176 1175567 1176514 + DHH subfamily 1 protein gene gene1102 http://www.ncbi.nlm.nih.gov/gene/?term=spr1176 spr1177 spr1177 rpmE2 rpmE2 1176610 1176852 + 50S ribosomal protein L31 RpmE2%3B there appears to be two types of ribosomal proteins L31 in bacterial genomes%3B some contain a CxxC motif while others do not%3B Bacillus subtilis has both types%3B the proteins in this cluster do not have the CXXC motif%3B RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth%3B expression of ytiA is controlled by a zinc-specific transcriptional repressor%3B RpmE contains one zinc ion and a CxxC motif is responsible for this binding%3B forms an RNP particle along with proteins L5%2C L18%2C and L25 and 5S rRNA%3B found crosslinked to L2 and L25 and EF-G%3B may be near the peptidyltransferase site of the 50S ribosome gene gene1103 http://www.ncbi.nlm.nih.gov/gene/?term=spr1177 spr1178 spr1178 spr1178 1176909 1177487 - hypothetical protein gene gene1104 http://www.ncbi.nlm.nih.gov/gene/?term=spr1178 spr1179 spr1179 spr1179 1177462 1178466 - hypothetical protein gene gene1105 http://www.ncbi.nlm.nih.gov/gene/?term=spr1179 spr1180 spr1180 transposase_C transposase_C 1178518 1178922 - gene gene1106 http://www.ncbi.nlm.nih.gov/gene/?term=spr1180 spr1181 spr1181 gdhA gdhA 1179472 1180818 + glutamate dehydrogenase converts 2-oxoglutarate to glutamate%3B in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction%3B uses NADPH%3B forms a homohexamer gene gene1107 http://www.ncbi.nlm.nih.gov/gene/?term=spr1181 spr1182 spr1182 spr1182 1181314 1181484 - hypothetical protein gene gene1108 http://www.ncbi.nlm.nih.gov/gene/?term=spr1182 spr1183 spr1183 spr1183 1181497 1182138 - ABC transporter ATP-binding protein gene gene1109 http://www.ncbi.nlm.nih.gov/gene/?term=spr1183 spr1184 spr1184 spr1184 1182410 1182917 + gene gene1110 http://www.ncbi.nlm.nih.gov/gene/?term=spr1184 spr1185 spr1185 spr1185 1183138 1183341 - hypothetical protein gene gene1111 http://www.ncbi.nlm.nih.gov/gene/?term=spr1185 spr1188 spr1188 cdd cdd 1184308 1184715 - cytidine deaminase gene gene1112 http://www.ncbi.nlm.nih.gov/gene/?term=spr1188 spr1189 spr1189 spr1189 1185003 1185491 - hypothetical protein gene gene1113 http://www.ncbi.nlm.nih.gov/gene/?term=spr1189 spr1190 spr1190 spr1190 1185496 1186914 - hypothetical protein gene gene1114 http://www.ncbi.nlm.nih.gov/gene/?term=spr1190 spr1191 spr1191 appD appD 1186915 1188897 - peptide ABC transporter ATP-binding protein gene gene1115 http://www.ncbi.nlm.nih.gov/gene/?term=spr1191 spr1192 spr1192 appC appC 1188910 1189761 - peptide ABC transporter permease gene gene1116 http://www.ncbi.nlm.nih.gov/gene/?term=spr1192 spr1193 spr1193 appB appB 1189778 1190773 - peptide ABC transporter permease gene gene1117 http://www.ncbi.nlm.nih.gov/gene/?term=spr1193 spr1194 spr1194 appA appA 1190838 1192466 - oligopeptide ABC transporter substrate-binding protein gene gene1118 http://www.ncbi.nlm.nih.gov/gene/?term=spr1194 spr1195 spr1195 spr1195 1192548 1193471 - hypothetical protein gene gene1119 http://www.ncbi.nlm.nih.gov/gene/?term=spr1195 spr1196 spr1196 nanE nanE 1193495 1194193 - N-acetylmannosamine-6-phosphate 2-epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene1120 http://www.ncbi.nlm.nih.gov/gene/?term=spr1196 spr1199 spr1199 spr1199 1195086 1195307 - hypothetical protein gene gene1121 http://www.ncbi.nlm.nih.gov/gene/?term=spr1199 spr1201 spr1201 spr1201 1196371 1197690 - hypothetical protein gene gene1122 http://www.ncbi.nlm.nih.gov/gene/?term=spr1201 spr1202 spr1202 ABC-NDB ABC-NDB 1197693 1198451 - ABC transporter ATP-binding protein gene gene1123 http://www.ncbi.nlm.nih.gov/gene/?term=spr1202 spr1203 spr1203 ABC-NP ABC-NP 1198448 1200055 - drug efflux ABC transporter ATP-binding/permease gene gene1124 http://www.ncbi.nlm.nih.gov/gene/?term=spr1203 spr1204 spr1204 ptrB ptrB 1200052 1201992 - prolyl oligopeptidase gene gene1125 http://www.ncbi.nlm.nih.gov/gene/?term=spr1204 spr1205 spr1205 spr1205 1202025 1204661 - hypothetical protein gene gene1126 http://www.ncbi.nlm.nih.gov/gene/?term=spr1205 spr1206 spr1206 spr1206 1205152 1205739 - hypothetical protein gene gene1127 http://www.ncbi.nlm.nih.gov/gene/?term=spr1206 spr1207 spr1207 spr1207 1205988 1206368 - hypothetical protein gene gene1128 http://www.ncbi.nlm.nih.gov/gene/?term=spr1207 spr1208 spr1208 spr1208 1206423 1206701 - hypothetical protein gene gene1129 http://www.ncbi.nlm.nih.gov/gene/?term=spr1208 spr1209 spr1209 spr1209 1206709 1206963 - hypothetical protein gene gene1130 http://www.ncbi.nlm.nih.gov/gene/?term=spr1209 spr1210 spr1210 spr1210 1206960 1207172 - hypothetical protein gene gene1131 http://www.ncbi.nlm.nih.gov/gene/?term=spr1210 spr1211 spr1211 rplL rplL 1207321 1207689 - 50S ribosomal protein L7/L12 present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors gene gene1132 http://www.ncbi.nlm.nih.gov/gene/?term=spr1211 spr1212 spr1212 rplJ rplJ 1207765 1208265 - 50S ribosomal protein L10 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit gene gene1133 http://www.ncbi.nlm.nih.gov/gene/?term=spr1212 spr1214 spr1214 trzA trzA 1208515 1209831 - chlorohydrolase gene gene1134 http://www.ncbi.nlm.nih.gov/gene/?term=spr1214 spr1215 spr1215 ABC-N/P ABC-N/P 1210076 1211866 - ABC transporter ATP-binding protein/permease gene gene1135 http://www.ncbi.nlm.nih.gov/gene/?term=spr1215 spr1216 spr1216 ABC-N/P ABC-N/P 1211829 1213553 - ABC transporter ATP-binding protein/permease gene gene1136 http://www.ncbi.nlm.nih.gov/gene/?term=spr1216 spr1217 spr1217 msrA msrA 1213611 1214549 - bifunctional methionine sulfoxide reductase A/B protein this fusion consists of methionine sulfoxide A reductase at the N-terminus and B at the C-terminus%3B A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress%2C S and R epimers of methionine sulfoxide%2C respectively%3B a fusion gene gene1137 http://www.ncbi.nlm.nih.gov/gene/?term=spr1217 spr1218 spr1218 thrB thrB 1214845 1215714 - homoserine kinase catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate gene gene1138 http://www.ncbi.nlm.nih.gov/gene/?term=spr1218 spr1219 spr1219 hom hom 1215716 1217002 - homoserine dehydrogenase catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine gene gene1139 http://www.ncbi.nlm.nih.gov/gene/?term=spr1219 spr1220 spr1220 mecA mecA 1217153 1217890 - adaptor protein enables recognition and targeting of proteins for proteolysis%2C involved in negative regulation of competence gene gene1140 http://www.ncbi.nlm.nih.gov/gene/?term=spr1220 spr1221 spr1221 spr1221 1218032 1219066 - hypothetical protein gene gene1141 http://www.ncbi.nlm.nih.gov/gene/?term=spr1221 spr1222 spr1222 spr1222 1219095 1220528 - hypothetical protein gene gene1142 http://www.ncbi.nlm.nih.gov/gene/?term=spr1222 spr1223 spr1223 cps23FU cps23FU 1220544 1221530 - galactosyl transferase gene gene1143 http://www.ncbi.nlm.nih.gov/gene/?term=spr1223 spr1224 spr1224 spr1224 1221532 1222689 - hypothetical protein Similar to capsular polysaccharide biosynthsis protein gene gene1144 http://www.ncbi.nlm.nih.gov/gene/?term=spr1224 spr1225 spr1225 licD1 licD1 1222625 1223470 - licD protein gene gene1145 http://www.ncbi.nlm.nih.gov/gene/?term=spr1225 spr1226 spr1226 spr1226 1223749 1225023 - hypothetical protein transcriptional regulator gene gene1146 http://www.ncbi.nlm.nih.gov/gene/?term=spr1226 spr1227 spr1227 pheA pheA 1225020 1225868 - prephenate dehydratase catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis gene gene1147 http://www.ncbi.nlm.nih.gov/gene/?term=spr1227 spr1228 spr1228 aroK aroK 1225865 1226341 - shikimate kinase gene gene1148 http://www.ncbi.nlm.nih.gov/gene/?term=spr1228 spr1229 spr1229 aroA aroA 1226334 1227629 - 3-phosphoshikimate 1-carboxyvinyltransferase catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis gene gene1149 http://www.ncbi.nlm.nih.gov/gene/?term=spr1229 spr1230 spr1230 spr1230 1227709 1228047 - hypothetical protein gene gene1150 http://www.ncbi.nlm.nih.gov/gene/?term=spr1230 spr1231 spr1231 tyrA tyrA 1228058 1229161 - prephenate dehydrogenase catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate gene gene1151 http://www.ncbi.nlm.nih.gov/gene/?term=spr1231 spr1232 spr1232 aroC aroC 1229171 1230337 - chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene1152 http://www.ncbi.nlm.nih.gov/gene/?term=spr1232 spr1233 spr1233 aroB aroB 1230347 1231414 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene1153 http://www.ncbi.nlm.nih.gov/gene/?term=spr1233 spr1234 spr1234 aroE aroE 1231433 1232287 - shikimate 5-dehydrogenase AroE%3B catalyzes the conversion of shikimate to 3-dehydroshikimate gene gene1154 http://www.ncbi.nlm.nih.gov/gene/?term=spr1234 spr1235 spr1235 aroD aroD 1232277 1232954 - 3-dehydroquinate dehydratase catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis gene gene1155 http://www.ncbi.nlm.nih.gov/gene/?term=spr1235 spr1236 spr1236 spr1236 1232951 1234123 - hypothetical protein gene gene1156 http://www.ncbi.nlm.nih.gov/gene/?term=spr1236 spr1237 spr1237 spr1237 1234801 1236462 - hypothetical protein gene gene1157 http://www.ncbi.nlm.nih.gov/gene/?term=spr1237 spr1238 spr1238 ABC-NBD ABC-NBD 1236416 1237222 - ABC transporter ATP-binding protein gene gene1158 http://www.ncbi.nlm.nih.gov/gene/?term=spr1238 spr1239 spr1239 amy amy 1237343 1238797 + cytoplasmic alpha-amylase converts 1%2C4-alpha-D-glucans to maltodextrin gene gene1159 http://www.ncbi.nlm.nih.gov/gene/?term=spr1239 spr1240 spr1240 alaS alaS 1238887 1241505 - alanyl-tRNA synthetase Catalyzes a two-step reaction%2C first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1160 http://www.ncbi.nlm.nih.gov/gene/?term=spr1240 spr1241 spr1241 spr1241 1241527 1242024 - hypothetical protein gene gene1161 http://www.ncbi.nlm.nih.gov/gene/?term=spr1241 spr1242 spr1242 spr1242 1242287 1242526 - hypothetical protein gene gene1162 http://www.ncbi.nlm.nih.gov/gene/?term=spr1242 spr1243 spr1243 potD potD 1242787 1243857 - spermidine/putrescine ABC transporter substrate-binding protein gene gene1163 http://www.ncbi.nlm.nih.gov/gene/?term=spr1243 spr1244 spr1244 potC potC 1243854 1244627 - spermidine/putrescine ABC transporter permease gene gene1164 http://www.ncbi.nlm.nih.gov/gene/?term=spr1244 spr1245 spr1245 potB potB 1244624 1245451 - spermidine/putrescine ABC transporter permease gene gene1165 http://www.ncbi.nlm.nih.gov/gene/?term=spr1245 spr1246 spr1246 potA potA 1245411 1246568 - spermidine/putrescine ABC transporter ATP-binding protein gene gene1166 http://www.ncbi.nlm.nih.gov/gene/?term=spr1246 spr1247 spr1247 murB murB 1246627 1247577 - UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene1167 http://www.ncbi.nlm.nih.gov/gene/?term=spr1247 spr1248 spr1248 spr1248 1247689 1248441 - hypothetical protein gene gene1168 http://www.ncbi.nlm.nih.gov/gene/?term=spr1248 spr1249 spr1249 aldB aldB 1248451 1249182 - alpha-acetolactate decarboxylase gene gene1169 http://www.ncbi.nlm.nih.gov/gene/?term=spr1249 spr1250 spr1250 spr1250 1249324 1250595 + hypothetical protein gene gene1170 http://www.ncbi.nlm.nih.gov/gene/?term=spr1250 spr1251 spr1251 glnH glnH 1250615 1251430 - amino acid ABC transporter amino acid-binding protein gene gene1171 http://www.ncbi.nlm.nih.gov/gene/?term=spr1251 spr1252 spr1252 phoU phoU 1251587 1252240 - phosphate transporter PhoU gene gene1172 http://www.ncbi.nlm.nih.gov/gene/?term=spr1252 spr1253 spr1253 pstB pstB 1252252 1253010 - phosphate transporter ATP-binding protein ATP-binding protein%3B PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation gene gene1173 http://www.ncbi.nlm.nih.gov/gene/?term=spr1253 spr1254 spr1254 pstB pstB 1253023 1253826 - phosphate transporter ATP-binding protein ATP-binding protein%3B PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation gene gene1174 http://www.ncbi.nlm.nih.gov/gene/?term=spr1254 spr1255 spr1255 pstA pstA 1253837 1254721 - phosphate ABC transporter permease gene gene1175 http://www.ncbi.nlm.nih.gov/gene/?term=spr1255 spr1256 spr1256 pstC pstC 1254711 1255628 - phosphate ABC transporter permease gene gene1176 http://www.ncbi.nlm.nih.gov/gene/?term=spr1256 spr1257 spr1257 pstS pstS 1255628 1256506 - phosphate ABC transporter substrate+B766-binding protein gene gene1177 http://www.ncbi.nlm.nih.gov/gene/?term=spr1257 spr1258 spr1258 spr1258 1257080 1258384 - gene gene1178 http://www.ncbi.nlm.nih.gov/gene/?term=spr1258 spr1260 spr1260 spr1260 1258385 1259233 - inositol monophosphatase Similar to E. coli extragenic suppressor protein SuhB gene gene1179 http://www.ncbi.nlm.nih.gov/gene/?term=spr1260 spr1261 spr1261 spr1261 1259148 1259426 - hypothetical protein gene gene1180 http://www.ncbi.nlm.nih.gov/gene/?term=spr1261 spr1262 spr1262 spxA spxA 1259426 1259827 - transcriptional regulator Spx the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters%3B in Bacillus subtilis this protein is a substrate for ClpXP protease%3B blocks transcription of the competence regulatory gene encoded by the srf operon%3B regulates a number of genes involved in thiol homeostasis including trxA and trxB%3B monomeric member of ArsC family of proteins%3B does not bind DNA%3B contains a disulfide bond between C10 and C13 which may sense disulfide stress gene gene1181 http://www.ncbi.nlm.nih.gov/gene/?term=spr1262 spr1263 spr1263 spr1263 1260037 1260687 - hypothetical protein gene gene1182 http://www.ncbi.nlm.nih.gov/gene/?term=spr1263 spr1264 spr1264 nagD nagD 1260644 1261417 - N-acetyl-glucosamine matabolism gene gene1183 http://www.ncbi.nlm.nih.gov/gene/?term=spr1264 spr1265 spr1265 spr1265 1261428 1262165 - acyl-ACP thioesterase Acyl-ACP thioesterase gene gene1184 http://www.ncbi.nlm.nih.gov/gene/?term=spr1265 spr1266 spr1266 hemN hemN 1262170 1263300 - coproporphyrinogen III oxidase catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III gene gene1185 http://www.ncbi.nlm.nih.gov/gene/?term=spr1266 spr1267 spr1267 spr1267 1263384 1263773 - hypothetical protein gene gene1186 http://www.ncbi.nlm.nih.gov/gene/?term=spr1267 spr1268 spr1268 spr1268 1263789 1264172 - hypothetical protein gene gene1187 http://www.ncbi.nlm.nih.gov/gene/?term=spr1268 spr1269 spr1269 lgt lgt 1264173 1264973 - prolipoprotein diacylglyceryl transferase transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein gene gene1188 http://www.ncbi.nlm.nih.gov/gene/?term=spr1269 spr1270 spr1270 hprK hprK 1264954 1265904 - HPr kinase/phosphorylase catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system gene gene1189 http://www.ncbi.nlm.nih.gov/gene/?term=spr1270 spr1271 spr1271 rpsU rpsU 1266019 1266219 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene1190 http://www.ncbi.nlm.nih.gov/gene/?term=spr1271 spr1272 spr1272 nagB nagB 1266335 1267057 - glucosamine-6-phosphate isomerase gene gene1191 http://www.ncbi.nlm.nih.gov/gene/?term=spr1272 spr1273 spr1273 queA queA 1267181 1268221 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene1192 http://www.ncbi.nlm.nih.gov/gene/?term=spr1273 spr1275 spr1275 spr1275 1270613 1271164 - hypothetical protein alanine acetyl transferase gene gene1193 http://www.ncbi.nlm.nih.gov/gene/?term=spr1275 spr1276 spr1276 nadE nadE 1271411 1272235 - NAD synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene1194 http://www.ncbi.nlm.nih.gov/gene/?term=spr1276 spr1277 spr1277 spr1277 1272232 1273692 - nicotinate phosphoribosyltransferase catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate gene gene1195 http://www.ncbi.nlm.nih.gov/gene/?term=spr1277 spr1278 spr1278 spr1278 1273808 1274296 - hypothetical protein gene gene1196 http://www.ncbi.nlm.nih.gov/gene/?term=spr1278 spr1279 spr1279 spr1279 1274286 1274525 - transcriptional repressor transcription regulator gene gene1197 http://www.ncbi.nlm.nih.gov/gene/?term=spr1279 spr1280 spr1280 spr1280 1274880 1275608 - hypothetical protein gene gene1198 http://www.ncbi.nlm.nih.gov/gene/?term=spr1280 spr1281 spr1281 ABC-NBD ABC-NBD 1275624 1276346 - ABC transporter ATP-binding protein gene gene1199 http://www.ncbi.nlm.nih.gov/gene/?term=spr1281 spr1282 spr1282 spr1282 1276851 1277576 - hypothetical protein gene gene1200 http://www.ncbi.nlm.nih.gov/gene/?term=spr1282 spr1284 spr1284 spr1284 1278165 1279469 - protease gene gene1201 http://www.ncbi.nlm.nih.gov/gene/?term=spr1284 spr1286 spr1286 spnIR-truncation spnIR-truncation 1280441 1280632 + gene gene1202 http://www.ncbi.nlm.nih.gov/gene/?term=spr1286 spr1287 spr1287 spnIM spnIM 1280629 1281819 + gene gene1203 http://www.ncbi.nlm.nih.gov/gene/?term=spr1287 spr1288 spr1288 spr1288 1282334 1283326 - hypothetical protein gene gene1204 http://www.ncbi.nlm.nih.gov/gene/?term=spr1288 spr1289 spr1289 ABC-N/P ABC-N/P 1283480 1285240 + ABC transporter ATP-binding protein/permease gene gene1205 http://www.ncbi.nlm.nih.gov/gene/?term=spr1289 spr1290 spr1290 ABC-N/P ABC-N/P 1285200 1286945 + ABC transporter ATP-binding protein gene gene1206 http://www.ncbi.nlm.nih.gov/gene/?term=spr1290 spr1291 spr1291 spr1291 1286956 1287540 + hypothetical protein gene gene1207 http://www.ncbi.nlm.nih.gov/gene/?term=spr1291 spr1292 spr1292 spr1292 1287540 1288235 + hypothetical protein gene gene1208 http://www.ncbi.nlm.nih.gov/gene/?term=spr1292 spr1293 spr1293 ABC-NBD ABC-NBD 1288223 1289587 + ABC transporter ATP-binding protein gene gene1209 http://www.ncbi.nlm.nih.gov/gene/?term=spr1293 spr1294 spr1294 spr1294 1290375 1290836 - hypothetical protein gene gene1210 http://www.ncbi.nlm.nih.gov/gene/?term=spr1294 spr1296 spr1296 spr1296 1291130 1291498 - hypothetical protein gene gene1211 http://www.ncbi.nlm.nih.gov/gene/?term=spr1296 spr1297 spr1297 spr1297 1291422 1291616 - hypothetical protein gene gene1212 http://www.ncbi.nlm.nih.gov/gene/?term=spr1297 spr1298 spr1298 transposase_E transposase_E 1291786 1292136 - transposase gene gene1213 http://www.ncbi.nlm.nih.gov/gene/?term=spr1298 spr1300 spr1300 guaA guaA 1292606 1294168 - GMP synthase contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene1214 http://www.ncbi.nlm.nih.gov/gene/?term=spr1300 spr1301 spr1301 spr1301 1294301 1295008 + hypothetical protein Probable transcription regulator%2C GntR family gene gene1215 http://www.ncbi.nlm.nih.gov/gene/?term=spr1301 spr1302 spr1302 spr1302 1295051 1296007 - hypothetical protein membrane protein gene gene1216 http://www.ncbi.nlm.nih.gov/gene/?term=spr1302 spr1303 spr1303 spr1303 1295956 1296894 - hypothetical protein gene gene1217 http://www.ncbi.nlm.nih.gov/gene/?term=spr1303 spr1304 spr1304 cppA cppA 1296891 1297631 - C3-degrading proteinase gene gene1218 http://www.ncbi.nlm.nih.gov/gene/?term=spr1304 spr1305 spr1305 spr1305 1297700 1298335 - hypothetical protein gene gene1219 http://www.ncbi.nlm.nih.gov/gene/?term=spr1305 spr1306 spr1306 spr1306 1298337 1299164 - Cof family protein gene gene1220 http://www.ncbi.nlm.nih.gov/gene/?term=spr1306 spr1307 spr1307 spr1307 1299186 1300542 - gene gene1221 http://www.ncbi.nlm.nih.gov/gene/?term=spr1307 spr1310 spr1310 def def 1300763 1301374 + peptide deformylase cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins%3B binds iron(2+) gene gene1222 http://www.ncbi.nlm.nih.gov/gene/?term=spr1310 spr1311 spr1311 trmH trmH 1301386 1302147 + tRNA (guanosine-2'-O-)-methyltransferase gene gene1223 http://www.ncbi.nlm.nih.gov/gene/?term=spr1311 spr1312 spr1312 trxB trxB 1302186 1303097 - thioredoxin reductase gene gene1224 http://www.ncbi.nlm.nih.gov/gene/?term=spr1312 spr1313 spr1313 spr1313 1303163 1303399 - hypothetical protein gene gene1225 http://www.ncbi.nlm.nih.gov/gene/?term=spr1313 spr1314 spr1314 ABC-NDB ABC-NDB 1303465 1304208 - amino acid ABC transporter ATP-binding protein gene gene1226 http://www.ncbi.nlm.nih.gov/gene/?term=spr1314 spr1315 spr1315 ABC-MSP ABC-MSP 1304208 1305008 - amino acid ABC transporter permease gene gene1227 http://www.ncbi.nlm.nih.gov/gene/?term=spr1315 spr1316 spr1316 spr1316 1305166 1305522 - hypothetical protein Similar to arsenate reductase gene gene1228 http://www.ncbi.nlm.nih.gov/gene/?term=spr1316 spr1317 spr1317 ogt ogt 1305516 1306046 - methylated-DNA--protein-cysteine S-methyltransferase gene gene1229 http://www.ncbi.nlm.nih.gov/gene/?term=spr1317 spr1318 spr1318 spr1318 1306046 1306540 - hypothetical protein acetyltransferase gene gene1230 http://www.ncbi.nlm.nih.gov/gene/?term=spr1318 spr1319 spr1319 spr1319 1306669 1307121 + hypothetical protein gene gene1231 http://www.ncbi.nlm.nih.gov/gene/?term=spr1319 spr1320 spr1320 spr1320 1307118 1307765 + hemolysin Similar to hemolysin III gene gene1232 http://www.ncbi.nlm.nih.gov/gene/?term=spr1320 spr1321 spr1321 spr1321 1307786 1308367 - glutamine amidotransferase subunit PdxT with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate%3B PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia%3B PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate gene gene1233 http://www.ncbi.nlm.nih.gov/gene/?term=spr1321 spr1322 spr1322 pdx1 pdx1 1308368 1309261 - pyridoxal biosynthesis lyase PdxS with PdxT forms pyridoxal 5'-phosphate from glutamine%2C either ribose 5-phosphate or ribulose 5-phosphate%2C and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate gene gene1234 http://www.ncbi.nlm.nih.gov/gene/?term=spr1322 spr1323 spr1323 nox nox 1309395 1310774 - NADH oxidase gene gene1235 http://www.ncbi.nlm.nih.gov/gene/?term=spr1323 spr1324 spr1324 apbE apbE 1311068 1311991 + thiamine biosynthesis protein ApbE gene gene1236 http://www.ncbi.nlm.nih.gov/gene/?term=spr1324 spr1325 spr1325 spr1325 1312051 1312656 + hypothetical protein gene gene1237 http://www.ncbi.nlm.nih.gov/gene/?term=spr1325 spr1326 spr1326 spr1326 1312674 1313918 + oxidoreductase gene gene1238 http://www.ncbi.nlm.nih.gov/gene/?term=spr1326 spr1327 spr1327 spr1327 1314035 1314292 - hypothetical protein gene gene1239 http://www.ncbi.nlm.nih.gov/gene/?term=spr1327 spr1328 spr1328 glyS glyS 1314334 1316370 - glycyl-tRNA synthetase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene1240 http://www.ncbi.nlm.nih.gov/gene/?term=spr1328 spr1329 spr1329 glyQ glyQ 1316630 1317547 - glycyl-tRNA synthetase subunit alpha glycine--tRNA ligase alpha chain%3B GlyRS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene1241 http://www.ncbi.nlm.nih.gov/gene/?term=spr1329 spr1330 spr1330 spr1330 1317741 1318501 - gene gene1242 http://www.ncbi.nlm.nih.gov/gene/?term=spr1330 spr1332 spr1332 spr1332 1318774 1319616 - hypothetical protein oxidoreductase gene gene1243 http://www.ncbi.nlm.nih.gov/gene/?term=spr1332 spr1333 spr1333 pgdA pgdA 1319730 1321121 - peptidoglycan GlcNAc deacetylase gene gene1244 http://www.ncbi.nlm.nih.gov/gene/?term=spr1333 spr1334 spr1334 spr1334 1321356 1321733 - gene gene1245 http://www.ncbi.nlm.nih.gov/gene/?term=spr1334 spr1335 spr1335 mocA mocA 1321864 1322925 + oxidoreductase gene gene1246 http://www.ncbi.nlm.nih.gov/gene/?term=spr1335 spr1336 spr1336 DEAD/H DEAD/H 1322922 1324004 + DEAD RNA helicase gene gene1247 http://www.ncbi.nlm.nih.gov/gene/?term=spr1336 spr1339 spr1339 IS861-truncation IS861-truncation 1324655 1325487 - gene gene1248 http://www.ncbi.nlm.nih.gov/gene/?term=spr1339 spr1343 spr1343 tuf tuf 1326964 1328160 - elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene1249 http://www.ncbi.nlm.nih.gov/gene/?term=spr1343 spr1344 spr1344 glpF glpF 1329082 1329951 - glycerol uptake facilitator protein gene gene1250 http://www.ncbi.nlm.nih.gov/gene/?term=spr1344 spr1345 spr1345 spr1345 1330175 1330783 - cell wall surface anchor family protein gene gene1251 http://www.ncbi.nlm.nih.gov/gene/?term=spr1345 spr1346 spr1346 spr1346 1330741 1331853 - hypothetical protein gene gene1252 http://www.ncbi.nlm.nih.gov/gene/?term=spr1346 spr1347 spr1347 spr1347 1331958 1332212 - hypothetical protein gene gene1253 http://www.ncbi.nlm.nih.gov/gene/?term=spr1347 spr1348 spr1348 spr1348 1332206 1332448 - hypothetical protein gene gene1254 http://www.ncbi.nlm.nih.gov/gene/?term=spr1348 spr1350 spr1350 transposase_A transposase_A 1333089 1333353 - gene gene1255 http://www.ncbi.nlm.nih.gov/gene/?term=spr1350 spr1351 spr1351 pgm pgm 1333648 1335366 + phosphoglucomutase gene gene1256 http://www.ncbi.nlm.nih.gov/gene/?term=spr1351 spr1352 spr1352 bta bta 1335477 1335824 + bacterocin transport accessory protein gene gene1257 http://www.ncbi.nlm.nih.gov/gene/?term=spr1352 spr1353 spr1353 glnH glnH 1336103 1336939 - amino acid ABC transporter amino acid-binding protein gene gene1258 http://www.ncbi.nlm.nih.gov/gene/?term=spr1353 spr1354 spr1354 glnQ glnQ 1336952 1337581 - amino acid ABC transporter ATP-binding protein gene gene1259 http://www.ncbi.nlm.nih.gov/gene/?term=spr1354 spr1355 spr1355 glnP glnP 1337591 1338289 - amino acid ABC transporter permease gene gene1260 http://www.ncbi.nlm.nih.gov/gene/?term=spr1355 spr1356 spr1356 spr1356 1338378 1339622 - hypothetical protein gene gene1261 http://www.ncbi.nlm.nih.gov/gene/?term=spr1356 spr1357 spr1357 spr1357 1339597 1340763 - hypothetical protein membrane protein gene gene1262 http://www.ncbi.nlm.nih.gov/gene/?term=spr1357 spr1358 spr1358 spr1358 1340907 1341920 + hypothetical protein gene gene1263 http://www.ncbi.nlm.nih.gov/gene/?term=spr1358 spr1359 spr1359 atpC atpC 1341965 1342384 - ATP synthase F0F1 subunit epsilon part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene1264 http://www.ncbi.nlm.nih.gov/gene/?term=spr1359 spr1360 spr1360 atpD atpD 1342395 1343801 - ATP synthase F0F1 subunit beta Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit gene gene1265 http://www.ncbi.nlm.nih.gov/gene/?term=spr1360 spr1361 spr1361 atpG atpG 1343887 1344765 - ATP synthase F0F1 subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene1266 http://www.ncbi.nlm.nih.gov/gene/?term=spr1361 spr1362 spr1362 atpA atpA 1344781 1346286 - ATP synthase F0F1 subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene1267 http://www.ncbi.nlm.nih.gov/gene/?term=spr1362 spr1363 spr1363 atpH atpH 1346301 1346837 - ATP synthase F0F1 subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene1268 http://www.ncbi.nlm.nih.gov/gene/?term=spr1363 spr1364 spr1364 atpF atpF 1346837 1347331 - ATP synthase F0F1 subunit B Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. gene gene1269 http://www.ncbi.nlm.nih.gov/gene/?term=spr1364 spr1365 spr1365 atpB atpB 1347345 1348061 - ATP synthase F0F1 subunit A Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene1270 http://www.ncbi.nlm.nih.gov/gene/?term=spr1365 spr1366 spr1366 atpE atpE 1348096 1348296 - ATP synthase F0F1 subunit C produces ATP from ADP in the presence of a proton gradient across the membrane%3B subunit C is part of the membrane proton channel F0 gene gene1271 http://www.ncbi.nlm.nih.gov/gene/?term=spr1366 spr1367 spr1367 IS1239 IS1239 1348371 1349378 - transposase gene gene1272 http://www.ncbi.nlm.nih.gov/gene/?term=spr1367 spr1368 spr1368 spr1368 1349823 1350305 - hypothetical protein gene gene1273 http://www.ncbi.nlm.nih.gov/gene/?term=spr1368 spr1369 spr1369 greA greA 1350774 1351265 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene1274 http://www.ncbi.nlm.nih.gov/gene/?term=spr1369 spr1370 spr1370 spr1370 1351327 1352982 - hypothetical protein gene gene1275 http://www.ncbi.nlm.nih.gov/gene/?term=spr1370 spr1371 spr1371 spr1371 1353063 1353557 - hypothetical protein acetyltransferase gene gene1276 http://www.ncbi.nlm.nih.gov/gene/?term=spr1371 spr1372 spr1372 spr1372 1353554 1354018 - hypothetical protein N-terminal acetyltransferase related protein gene gene1277 http://www.ncbi.nlm.nih.gov/gene/?term=spr1372 spr1373 spr1373 murC murC 1354028 1355362 - UDP-N-acetylmuramate--L-alanine ligase Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis gene gene1278 http://www.ncbi.nlm.nih.gov/gene/?term=spr1373 spr1374 spr1374 spr1374 1355373 1355990 - hypothetical protein gene gene1279 http://www.ncbi.nlm.nih.gov/gene/?term=spr1374 spr1375 spr1375 snf snf 1356038 1359136 - Snf2 family protein gene gene1280 http://www.ncbi.nlm.nih.gov/gene/?term=spr1375 spr1376 spr1376 patB patB 1359229 1360395 - aminotransferase%2C class II gene gene1281 http://www.ncbi.nlm.nih.gov/gene/?term=spr1376 spr1377 spr1377 metB metB 1360403 1361497 - cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene1282 http://www.ncbi.nlm.nih.gov/gene/?term=spr1377 spr1378 spr1378 ABC-MSP-truncation ABC-MSP-truncation 1361655 1362777 - gene gene1283 http://www.ncbi.nlm.nih.gov/gene/?term=spr1378 spr1382 spr1382 aliB aliB 1363510 1365468 - peptide ABC transporter substrate-binding protein gene gene1284 http://www.ncbi.nlm.nih.gov/gene/?term=spr1382 spr1383 spr1383 PST_transporter PST_transporter 1365671 1367293 - polysaccharide biosynthesis protein gene gene1285 http://www.ncbi.nlm.nih.gov/gene/?term=spr1383 spr1384 spr1384 murE murE 1367399 1368844 + UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine gene gene1286 http://www.ncbi.nlm.nih.gov/gene/?term=spr1384 spr1385 spr1385 spr1385 1368890 1369084 - hypothetical protein gene gene1287 http://www.ncbi.nlm.nih.gov/gene/?term=spr1385 spr1386 spr1386 spr1386 1369185 1369780 - gene gene1288 http://www.ncbi.nlm.nih.gov/gene/?term=spr1386 spr1388 spr1388 spr1388 1369817 1370329 - hypothetical protein gene gene1289 http://www.ncbi.nlm.nih.gov/gene/?term=spr1388 spr1389 spr1389 ppaC ppaC 1370416 1371351 - manganese-dependent inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene1290 http://www.ncbi.nlm.nih.gov/gene/?term=spr1389 spr1390 spr1390 spr1390 1371422 1371721 - hypothetical protein gene gene1291 http://www.ncbi.nlm.nih.gov/gene/?term=spr1390 spr1391 spr1391 spr1391 1371711 1372460 - hypothetical protein gene gene1292 http://www.ncbi.nlm.nih.gov/gene/?term=spr1391 spr1392 spr1392 spr1392 1372514 1372900 - hypothetical protein Similar to general stress protein GSP13 from Lactococcus lactis subsp. lactis and Bacillus subtilis gene gene1293 http://www.ncbi.nlm.nih.gov/gene/?term=spr1392 spr1393 spr1393 spr1393 1372875 1374275 - Cof family protein/peptidyl-prolyl cis-trans isomerase gene gene1294 http://www.ncbi.nlm.nih.gov/gene/?term=spr1393 spr1394 spr1394 rpsR rpsR 1374570 1374809 - 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene1295 http://www.ncbi.nlm.nih.gov/gene/?term=spr1394 spr1395 spr1395 ssbA ssbA 1374841 1375311 - single-stranded DNA-binding protein binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA gene gene1296 http://www.ncbi.nlm.nih.gov/gene/?term=spr1395 spr1396 spr1396 rpsF rpsF 1375323 1375613 - 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene1297 http://www.ncbi.nlm.nih.gov/gene/?term=spr1396 spr1397 spr1397 asnC asnC 1375766 1377109 - asparaginyl-tRNA synthetase catalyzes a two-step reaction%2C first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1298 http://www.ncbi.nlm.nih.gov/gene/?term=spr1397 spr1398 spr1398 spr1398 1377128 1377499 - hypothetical protein gene gene1299 http://www.ncbi.nlm.nih.gov/gene/?term=spr1398 spr1399 spr1399 aspB aspB 1377486 1378673 - aspartate aminotransferase catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate gene gene1300 http://www.ncbi.nlm.nih.gov/gene/?term=spr1399 spr1400 spr1400 spr1400 1378670 1379158 - hypothetical protein gene gene1301 http://www.ncbi.nlm.nih.gov/gene/?term=spr1400 spr1402 spr1402 spr1402 1379398 1380027 + hypothetical protein gene gene1302 http://www.ncbi.nlm.nih.gov/gene/?term=spr1402 spr1403 spr1403 spr1403 1380265 1387920 - hypothetical protein gene gene1303 http://www.ncbi.nlm.nih.gov/gene/?term=spr1403 spr1404 spr1404 spr1404 1388112 1389620 + hypothetical protein Mga-like regulatory protein gene gene1304 http://www.ncbi.nlm.nih.gov/gene/?term=spr1404 spr1405 spr1405 spr1405 1389671 1390399 - hypothetical protein gene gene1305 http://www.ncbi.nlm.nih.gov/gene/?term=spr1405 spr1406 spr1406 spr1406 1390478 1390657 - hypothetical protein gene gene1306 http://www.ncbi.nlm.nih.gov/gene/?term=spr1406 spr1407 spr1407 spr1407 1390809 1392404 - hypothetical protein gene gene1307 http://www.ncbi.nlm.nih.gov/gene/?term=spr1407 spr1408 spr1408 def def 1392416 1392826 - peptide deformylase cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins%3B binds iron(2+) gene gene1308 http://www.ncbi.nlm.nih.gov/gene/?term=spr1408 spr1409 spr1409 spr1409 1392942 1393733 - glutathione S-transferase YghU YghU%3B B2989%3B one of eight glutathione transferases from E. coli gene gene1309 http://www.ncbi.nlm.nih.gov/gene/?term=spr1409 spr1410 spr1410 pacL pacL 1393746 1396442 - calcium transporter P-type ATPase calcium transporter gene gene1310 http://www.ncbi.nlm.nih.gov/gene/?term=spr1410 spr1411 spr1411 spr1411 1396746 1397930 + cation efflux family protein Probable cation transporter gene gene1311 http://www.ncbi.nlm.nih.gov/gene/?term=spr1411 spr1412 spr1412 ABC-NBD ABC-NBD 1398073 1399944 - ABC transporter ATP-binding protein gene gene1312 http://www.ncbi.nlm.nih.gov/gene/?term=spr1412 spr1413 spr1413 cca cca 1399941 1401140 - tRNA CCA-pyrophosphorylase catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA%3B these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity gene gene1313 http://www.ncbi.nlm.nih.gov/gene/?term=spr1413 spr1414 spr1414 dapB dapB 1401137 1401904 - dihydrodipicolinate reductase catalyzes the reduction of 2%2C3-dihydrodipicolinate to 2%2C3%2C4%2C5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis gene gene1314 http://www.ncbi.nlm.nih.gov/gene/?term=spr1414 spr1415 spr1415 spr1415 1402181 1403029 - hypothetical protein Similar to DegV of B.subtilis gene gene1315 http://www.ncbi.nlm.nih.gov/gene/?term=spr1415 spr1416 spr1416 spr1416 1403031 1403417 - hypothetical protein gene gene1316 http://www.ncbi.nlm.nih.gov/gene/?term=spr1416 spr1417 spr1417 glmM glmM 1403479 1404831 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene1317 http://www.ncbi.nlm.nih.gov/gene/?term=spr1417 spr1418 spr1418 spr1418 1404855 1405634 - hypothetical protein gene gene1318 http://www.ncbi.nlm.nih.gov/gene/?term=spr1418 spr1419 spr1419 spr1419 1405621 1406499 - hypothetical protein gene gene1319 http://www.ncbi.nlm.nih.gov/gene/?term=spr1419 spr1420 spr1420 spr1420 1406396 1406569 - hypothetical protein gene gene1320 http://www.ncbi.nlm.nih.gov/gene/?term=spr1420 spr1421 spr1421 trxB trxB 1406614 1407582 + pyridine nucleotide-disulphide oxidoreductase gene gene1321 http://www.ncbi.nlm.nih.gov/gene/?term=spr1421 spr1422 spr1422 spr1422 1407616 1408527 - hypothetical protein gene gene1322 http://www.ncbi.nlm.nih.gov/gene/?term=spr1422 spr1423 spr1423 spr1423 1408524 1409501 - hypothetical protein gene gene1323 http://www.ncbi.nlm.nih.gov/gene/?term=spr1423 spr1424 spr1424 spr1424 1409498 1410388 - hypothetical protein gene gene1324 http://www.ncbi.nlm.nih.gov/gene/?term=spr1424 spr1425 spr1425 aldR aldR 1410440 1410820 - endoribonuclease L-PSP gene gene1325 http://www.ncbi.nlm.nih.gov/gene/?term=spr1425 spr1426 spr1426 engB engB 1410831 1411424 - ribosome biogenesis GTP-binding protein YsxC binds guanine nucleotides%3B in Escherichia coli depletion results in defective cell division and filamentation%3B in Bacillus subtilis this gene is essential gene gene1326 http://www.ncbi.nlm.nih.gov/gene/?term=spr1426 spr1427 spr1427 clpX clpX 1411427 1412659 - ATP-dependent protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene1327 http://www.ncbi.nlm.nih.gov/gene/?term=spr1427 spr1428 spr1428 spr1428 1412691 1412861 - hypothetical protein gene gene1328 http://www.ncbi.nlm.nih.gov/gene/?term=spr1428 spr1429 spr1429 dfr dfr 1412861 1413367 - dihydrofolate reductase gene gene1329 http://www.ncbi.nlm.nih.gov/gene/?term=spr1429 spr1430 spr1430 dpr dpr 1413497 1414033 - non-heme iron-containing ferritin gene gene1330 http://www.ncbi.nlm.nih.gov/gene/?term=spr1430 spr1431 spr1431 lytC lytC 1414511 1416016 - 1%2C4-beta-N-acetylmuramidase gene gene1331 http://www.ncbi.nlm.nih.gov/gene/?term=spr1431 spr1432 spr1432 tpiA tpiA 1416054 1416833 - triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene1332 http://www.ncbi.nlm.nih.gov/gene/?term=spr1432 spr1433 spr1433 spr1433 1416910 1417587 - hypothetical protein gene gene1333 http://www.ncbi.nlm.nih.gov/gene/?term=spr1433 spr1434 spr1434 metA metA 1417596 1418540 - homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene1334 http://www.ncbi.nlm.nih.gov/gene/?term=spr1434 spr1435 spr1435 apt apt 1418722 1419252 - adenine phosphoribosyltransferase catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis gene gene1335 http://www.ncbi.nlm.nih.gov/gene/?term=spr1435 spr1436 spr1436 spr1436 1419322 1420080 - hypothetical protein Methyltransferase-like protein gene gene1336 http://www.ncbi.nlm.nih.gov/gene/?term=spr1436 spr1437 spr1437 msmK msmK 1420581 1421711 - sugar ABC transporter ATP-binding protein gene gene1337 http://www.ncbi.nlm.nih.gov/gene/?term=spr1437 spr1438 spr1438 entB entB 1422161 1422736 - isochorismatase gene gene1339 http://www.ncbi.nlm.nih.gov/gene/?term=spr1438 spr1439 spr1439 codY codY 1422736 1423524 - transcriptional repressor CodY CodY%3B DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor gene gene1340 http://www.ncbi.nlm.nih.gov/gene/?term=spr1439 spr1440 spr1440 spr1440 1423788 1425362 - ATP-dependent RNA helicase Probable ATP-dependent RNA helicase gene gene1341 http://www.ncbi.nlm.nih.gov/gene/?term=spr1440 spr1441 spr1441 oxlT oxlT 1425561 1426787 - oxalate:formate antiporter gene gene1342 http://www.ncbi.nlm.nih.gov/gene/?term=spr1441 spr1442 spr1442 merA merA 1426977 1428293 + pyridine nucleotide-disulfide oxidoreductase Involved in disulfide oxidoreductase activity and electron transport gene gene1343 http://www.ncbi.nlm.nih.gov/gene/?term=spr1442 spr1443 spr1443 spr1443 1428392 1429735 + hypothetical protein three-substrate amide ligase belonging tothe mur-ligase gene gene1344 http://www.ncbi.nlm.nih.gov/gene/?term=spr1443 spr1444 spr1444 cobQ cobQ 1429735 1430517 + hypothetical protein gene gene1345 http://www.ncbi.nlm.nih.gov/gene/?term=spr1444 spr1445 spr1445 pepQ pepQ 1430643 1431725 + dipeptidase gene gene1346 http://www.ncbi.nlm.nih.gov/gene/?term=spr1445 spr1446 spr1446 spr1446 1432048 1432536 - integrase gene gene1347 http://www.ncbi.nlm.nih.gov/gene/?term=spr1446 spr1447 spr1447 spr1447 1432598 1432870 - hypothetical protein gene gene1348 http://www.ncbi.nlm.nih.gov/gene/?term=spr1447 spr1448 spr1448 spr1448 1433096 1433368 - hypothetical protein gene gene1349 http://www.ncbi.nlm.nih.gov/gene/?term=spr1448 spr1449 spr1449 spr1449 1433540 1434001 - hypothetical protein gene gene1350 http://www.ncbi.nlm.nih.gov/gene/?term=spr1449 spr1450 spr1450 pdxK pdxK 1433979 1434752 - phosphomethylpyrimidine kinase catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine gene gene1351 http://www.ncbi.nlm.nih.gov/gene/?term=spr1450 spr1451 spr1451 truA truA 1434742 1435491 - tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene1352 http://www.ncbi.nlm.nih.gov/gene/?term=spr1451 spr1453 spr1453 MFS_transporter MFS_transporter 1435804 1436955 - major facilitator transporter gene gene1353 http://www.ncbi.nlm.nih.gov/gene/?term=spr1453 spr1454 spr1454 spr1454 1437195 1437824 - hypothetical protein gene gene1354 http://www.ncbi.nlm.nih.gov/gene/?term=spr1454 spr1455 spr1455 phnA phnA 1437827 1438165 - hypothetical protein gene gene1355 http://www.ncbi.nlm.nih.gov/gene/?term=spr1455 spr1456 spr1456 cmk cmk 1438296 1438967 - cytidylate kinase Catalyzes the formation of (d)CDP from ATP and (d)CMP gene gene1356 http://www.ncbi.nlm.nih.gov/gene/?term=spr1456 spr1457 spr1457 spr1457 1438976 1439452 - hypothetical protein gene gene1357 http://www.ncbi.nlm.nih.gov/gene/?term=spr1457 spr1458 spr1458 fer fer 1439432 1439710 + ferredoxin gene gene1358 http://www.ncbi.nlm.nih.gov/gene/?term=spr1458 spr1459 spr1459 gtrB gtrB 1439772 1440863 - glycosil transferase gene gene1359 http://www.ncbi.nlm.nih.gov/gene/?term=spr1459 spr1460 spr1460 galE galE 1440727 1441746 - UDP-glucose 4-epimerase gene gene1360 http://www.ncbi.nlm.nih.gov/gene/?term=spr1460 spr1461 spr1461 spr1461 1442047 1443159 - hypothetical protein Probable oxidase gene gene1361 http://www.ncbi.nlm.nih.gov/gene/?term=spr1461 spr1462 spr1462 spr1462 1443167 1443964 - hypothetical protein gene gene1362 http://www.ncbi.nlm.nih.gov/gene/?term=spr1462 spr1463 spr1463 spr1463 1443951 1444628 - hypothetical protein gene gene1363 http://www.ncbi.nlm.nih.gov/gene/?term=spr1463 spr1464 spr1464 ctpE ctpE 1444730 1447066 - metal cation transporter P-type ATPase gene gene1364 http://www.ncbi.nlm.nih.gov/gene/?term=spr1464 spr1465 spr1465 spr1465 1447154 1447948 + hypothetical protein Probable member of acyltransferase gene gene1365 http://www.ncbi.nlm.nih.gov/gene/?term=spr1465 spr1466 spr1466 cadD cadD 1448241 1448855 - cadmium resistance protein gene gene1366 http://www.ncbi.nlm.nih.gov/gene/?term=spr1466 spr1467 spr1467 rpsO rpsO 1449589 1449858 - 30S ribosomal protein S15 primary rRNA binding protein%3B helps nucleate assembly of 30S%3B binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA%3B autoregulates translation through interactions with the mRNA leader sequence gene gene1367 http://www.ncbi.nlm.nih.gov/gene/?term=spr1467 spr1468 spr1468 spr1468 1449999 1450628 - hypothetical protein gene gene1368 http://www.ncbi.nlm.nih.gov/gene/?term=spr1468 spr1470 spr1470 spr1470 1451498 1451821 + gene gene1369 http://www.ncbi.nlm.nih.gov/gene/?term=spr1470 spr1472 spr1472 thrS thrS 1451879 1453822 + threonyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene1370 http://www.ncbi.nlm.nih.gov/gene/?term=spr1472 spr1473 spr1473 hk01 hk01 1453871 1454845 - sensor histidine kinase gene gene1371 http://www.ncbi.nlm.nih.gov/gene/?term=spr1473 spr1474 spr1474 rr01 rr01 1454838 1455515 - DNA-binding response regulator gene gene1372 http://www.ncbi.nlm.nih.gov/gene/?term=spr1474 spr1475 spr1475 spr1475 1455671 1456744 + hypothetical protein gene gene1373 http://www.ncbi.nlm.nih.gov/gene/?term=spr1475 spr1476 spr1476 spr1476 1456835 1457137 - hypothetical protein gene gene1374 http://www.ncbi.nlm.nih.gov/gene/?term=spr1476 spr1477 spr1477 spr1477 1457206 1457643 - Rrf2 family protein gene gene1375 http://www.ncbi.nlm.nih.gov/gene/?term=spr1477 spr1479 spr1479 spr1479 1457719 1458567 - hypothetical protein gene gene1376 http://www.ncbi.nlm.nih.gov/gene/?term=spr1479 spr1480 spr1480 marR marR 1458673 1459323 + iron-dependent transcriptional regulator gene gene1377 http://www.ncbi.nlm.nih.gov/gene/?term=spr1480 spr1481 spr1481 spr1481 1459304 1459474 + hypothetical protein gene gene1378 http://www.ncbi.nlm.nih.gov/gene/?term=spr1481 spr1482 spr1482 spr1482 1459625 1460145 + gene gene1379 http://www.ncbi.nlm.nih.gov/gene/?term=spr1482 spr1483 spr1483 spr1483 1460276 1460713 + hypothetical protein gene gene1380 http://www.ncbi.nlm.nih.gov/gene/?term=spr1483 spr1484 spr1484 spr1484 1460808 1461107 - hypothetical protein gene gene1381 http://www.ncbi.nlm.nih.gov/gene/?term=spr1484 spr1485 spr1485 spr1485 1462009 1462423 + gene gene1382 http://www.ncbi.nlm.nih.gov/gene/?term=spr1485 spr1486 spr1486 spr1486 1462462 1462905 - D-tyrosyl-tRNA(Tyr) deacylase hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr)%3B possible defense mechanism against a harmful effect of D-tyrosine gene gene1383 http://www.ncbi.nlm.nih.gov/gene/?term=spr1486 spr1487 spr1487 relA relA 1462935 1465157 - GTP pyrophosphokinase gene gene1384 http://www.ncbi.nlm.nih.gov/gene/?term=spr1487 spr1490 spr1490 spr1490 1466101 1466781 + metallo-beta-lactamase superfamily protein Probable member of metallo-beta-lactamase superfamily gene gene1385 http://www.ncbi.nlm.nih.gov/gene/?term=spr1490 spr1491 spr1491 pepO pepO 1466904 1468796 - endopeptidase O gene gene1386 http://www.ncbi.nlm.nih.gov/gene/?term=spr1491 spr1492 spr1492 psaB psaB 1469087 1469809 + manganese ABC transporter ATP-binding protein gene gene1387 http://www.ncbi.nlm.nih.gov/gene/?term=spr1492 spr1493 spr1493 psaC psaC 1469806 1470654 + manganese ABC transporter permease gene gene1388 http://www.ncbi.nlm.nih.gov/gene/?term=spr1493 spr1494 spr1494 psaA psaA 1470686 1471615 + manganese ABC transporter substrate-binding protein gene gene1389 http://www.ncbi.nlm.nih.gov/gene/?term=spr1494 spr1495 spr1495 tpx tpx 1471738 1472229 + thiol peroxidase antioxidant activity%3B thioredoxin-dependent thiol peroxidase%3B forms homodimers in solution%3B shows substrate specificity to alkyl hydroperoxides%3B periplasmic protein gene gene1390 http://www.ncbi.nlm.nih.gov/gene/?term=spr1495 spr1496 spr1496 spr1496 1472325 1475099 - hypothetical protein gene gene1391 http://www.ncbi.nlm.nih.gov/gene/?term=spr1496 spr1497 spr1497 ABC-NBD ABC-NBD 1475035 1475745 - ABC transporter ATP-binding protein gene gene1392 http://www.ncbi.nlm.nih.gov/gene/?term=spr1497 spr1498 spr1498 spr1498 1475986 1478397 - hypothetical protein large secreted protein gene gene1393 http://www.ncbi.nlm.nih.gov/gene/?term=spr1498 spr1499 spr1499 gpmA gpmA 1478450 1479142 - phosphoglyceromutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene1394 http://www.ncbi.nlm.nih.gov/gene/?term=spr1499 spr1500 spr1500 spr1500 1479193 1479381 - hypothetical protein gene gene1395 http://www.ncbi.nlm.nih.gov/gene/?term=spr1500 spr1501 spr1501 spr1501 1479677 1480017 - gene gene1396 http://www.ncbi.nlm.nih.gov/gene/?term=spr1501 spr1502 spr1502 ileS ileS 1480465 1483257 - isoleucyl-tRNA synthetase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene1397 http://www.ncbi.nlm.nih.gov/gene/?term=spr1502 spr1503 spr1503 spr1503 1483401 1483562 - hypothetical protein gene gene1398 http://www.ncbi.nlm.nih.gov/gene/?term=spr1503 spr1505 spr1505 divIVA divIVA 1483605 1484405 - cell division protein DivIVA gene gene1399 http://www.ncbi.nlm.nih.gov/gene/?term=spr1505 spr1506 spr1506 spr1506 1484402 1485253 - hypothetical protein gene gene1400 http://www.ncbi.nlm.nih.gov/gene/?term=spr1506 spr1507 spr1507 spr1507 1485184 1485447 - hypothetical protein gene gene1401 http://www.ncbi.nlm.nih.gov/gene/?term=spr1507 spr1508 spr1508 spr1508 1485447 1485986 - hypothetical protein gene gene1402 http://www.ncbi.nlm.nih.gov/gene/?term=spr1508 spr1509 spr1509 spr1509 1485996 1486667 - hypothetical protein gene gene1403 http://www.ncbi.nlm.nih.gov/gene/?term=spr1509 spr1510 spr1510 ftsZ ftsZ 1486672 1487931 - cell division protein FtsZ GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene1404 http://www.ncbi.nlm.nih.gov/gene/?term=spr1510 spr1511 spr1511 ftsA ftsA 1487948 1489321 - cell division protein FtsA gene gene1405 http://www.ncbi.nlm.nih.gov/gene/?term=spr1511 spr1512 spr1512 spr1512 1489540 1490244 - hypothetical protein gene gene1406 http://www.ncbi.nlm.nih.gov/gene/?term=spr1512 spr1513 spr1513 mutT mutT 1490335 1490946 - MutT/nudix family protein gene gene1407 http://www.ncbi.nlm.nih.gov/gene/?term=spr1513 spr1514 spr1514 murF murF 1490933 1492306 - UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-alanyl-D-alanine ligase gene gene1408 http://www.ncbi.nlm.nih.gov/gene/?term=spr1514 spr1515 spr1515 ddl ddl 1492390 1493433 - D-alanyl-alanine synthetase A D-alanine--D-alanine ligase%3B DdlA%3B DdlB%3B cytoplasmic%3B catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis%3B there are two forms of this enzyme in Escherichia coli gene gene1409 http://www.ncbi.nlm.nih.gov/gene/?term=spr1515 spr1516 spr1516 recR recR 1493609 1494205 - recombination protein RecR involved in a recombinational process of DNA repair%2C independent of the recBC complex gene gene1410 http://www.ncbi.nlm.nih.gov/gene/?term=spr1516 spr1517 spr1517 pbp2b pbp2b 1494216 1496273 - penicillin-binding protein 2B gene gene1411 http://www.ncbi.nlm.nih.gov/gene/?term=spr1517 spr1518 spr1518 spr1518 1496473 1497324 + phosphosugar-binding transcriptional regulator Probable transcriptional regulator gene gene1412 http://www.ncbi.nlm.nih.gov/gene/?term=spr1518 spr1519 spr1519 glk glk 1497340 1498224 - ROK family protein gene gene1413 http://www.ncbi.nlm.nih.gov/gene/?term=spr1519 spr1522 spr1522 spr1522 1499342 1499806 - hypothetical protein gene gene1414 http://www.ncbi.nlm.nih.gov/gene/?term=spr1522 spr1523 spr1523 spr1523 1500093 1500437 - hypothetical protein gene gene1415 http://www.ncbi.nlm.nih.gov/gene/?term=spr1523 spr1524 spr1524 spr1524 1500534 1500986 - hypothetical protein gene gene1416 http://www.ncbi.nlm.nih.gov/gene/?term=spr1524 spr1525 spr1525 ABC-MSP ABC-MSP 1501259 1502098 - sugar ABC transporter permease gene gene1417 http://www.ncbi.nlm.nih.gov/gene/?term=spr1525 spr1526 spr1526 ABC-MSP ABC-MSP 1502114 1503010 - sugar ABC transporter permease gene gene1418 http://www.ncbi.nlm.nih.gov/gene/?term=spr1526 spr1527 spr1527 ABC-SBP ABC-SBP 1503232 1504560 - sugar ABC transporter substrate-binding protein gene gene1419 http://www.ncbi.nlm.nih.gov/gene/?term=spr1527 spr1528 spr1528 PTS-EII PTS-EII 1504685 1506217 - PTS system transporter subunit IIBC gene gene1420 http://www.ncbi.nlm.nih.gov/gene/?term=spr1528 spr1529 spr1529 nanE nanE 1506221 1506919 - N-acetylmannosamine-6-phosphate 2-epimerase Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate gene gene1421 http://www.ncbi.nlm.nih.gov/gene/?term=spr1529 spr1530 spr1530 spr1530 1507099 1508202 - hypothetical protein Probable Oxidoreductase%2C GFO/IDH/MOCA family gene gene1422 http://www.ncbi.nlm.nih.gov/gene/?term=spr1530 spr1531 spr1531 nanB nanB 1508214 1510307 - neuraminidase B gene gene1423 http://www.ncbi.nlm.nih.gov/gene/?term=spr1531 spr1532 spr1532 ABC-MSP ABC-MSP 1510325 1511158 - ABC transporter permease gene gene1424 http://www.ncbi.nlm.nih.gov/gene/?term=spr1532 spr1533 spr1533 ABC-MSP ABC-MSP 1511158 1512042 - ABC transporter permease gene gene1425 http://www.ncbi.nlm.nih.gov/gene/?term=spr1533 spr1534 spr1534 ABC-SBP ABC-SBP 1512121 1513458 - ABC transporter substrate-binding protein gene gene1426 http://www.ncbi.nlm.nih.gov/gene/?term=spr1534 spr1535 spr1535 spr1535 1513477 1513929 - hypothetical protein gene gene1427 http://www.ncbi.nlm.nih.gov/gene/?term=spr1535 spr1536 spr1536 nanA nanA 1514944 1518051 - neuraminidase A gene gene1428 http://www.ncbi.nlm.nih.gov/gene/?term=spr1536 spr1537 spr1537 spr1537 1518294 1518521 - hypothetical protein gene gene1429 http://www.ncbi.nlm.nih.gov/gene/?term=spr1537 spr1538 spr1538 axe1 axe1 1519416 1520396 - acetyl xylan esterase gene gene1430 http://www.ncbi.nlm.nih.gov/gene/?term=spr1538 spr1539 spr1539 recG recG 1520712 1522727 - ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene1431 http://www.ncbi.nlm.nih.gov/gene/?term=spr1539 spr1540 spr1540 alr alr 1522746 1523870 - alanine racemase converts L-alanine to D-alanine which is used in cell wall biosynthesis%3B binds one pyridoxal phosphate per monomer%3B forms a homodimer gene gene1432 http://www.ncbi.nlm.nih.gov/gene/?term=spr1540 spr1541 spr1541 acpS acpS 1523839 1524201 - 4'-phosphopantetheinyl transferase Catalyzes the formation of holo-ACP%2C which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids gene gene1433 http://www.ncbi.nlm.nih.gov/gene/?term=spr1541 spr1542 spr1542 aroF aroF 1524246 1525277 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C phenylalanine sensitive gene gene1434 http://www.ncbi.nlm.nih.gov/gene/?term=spr1542 spr1543 spr1543 aroG aroG 1525279 1526310 - phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene1435 http://www.ncbi.nlm.nih.gov/gene/?term=spr1543 spr1544 spr1544 secA secA 1526391 1528904 - preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene1436 http://www.ncbi.nlm.nih.gov/gene/?term=spr1544 spr1545 spr1545 spr1545 1529050 1529250 - hypothetical protein gene gene1437 http://www.ncbi.nlm.nih.gov/gene/?term=spr1545 spr1546 spr1546 ABC-NBD ABC-NBD 1529350 1530000 - ABC transporter ATP-binding protein gene gene1438 http://www.ncbi.nlm.nih.gov/gene/?term=spr1546 spr1547 spr1547 spr1547 1530004 1530681 - hypothetical protein gene gene1439 http://www.ncbi.nlm.nih.gov/gene/?term=spr1547 spr1548 spr1548 spr1548 1530638 1531429 - hypothetical protein gene gene1440 http://www.ncbi.nlm.nih.gov/gene/?term=spr1548 spr1549 spr1549 spr1549 1531451 1531843 - hypothetical protein gene gene1441 http://www.ncbi.nlm.nih.gov/gene/?term=spr1549 spr1550 spr1550 spr1550 1532170 1533021 + hypothetical protein Similar to MutR protein gene gene1442 http://www.ncbi.nlm.nih.gov/gene/?term=spr1550 spr1551 spr1551 spr1551 1533243 1533596 - hypothetical protein gene gene1443 http://www.ncbi.nlm.nih.gov/gene/?term=spr1551 spr1552 spr1552 spr1552 1533733 1534077 - hypothetical protein gene gene1444 http://www.ncbi.nlm.nih.gov/gene/?term=spr1552 spr1553 spr1553 engA engA 1534157 1535467 - GTP-binding protein EngA EngA%3B essential Neisserial GTPase%3B synchronizes cellular events by interacting with multiple targets with tandem G-domains%3B overexpression in Escherichia coli suppresses rrmJ mutation%3B structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains gene gene1445 http://www.ncbi.nlm.nih.gov/gene/?term=spr1553 spr1554 spr1554 frp frp 1535481 1536194 - nitroreductase gene gene1446 http://www.ncbi.nlm.nih.gov/gene/?term=spr1554 spr1555 spr1555 dnaI dnaI 1536191 1537087 - primosomal protein DnaI Primosomal protein that may act to load helicase DnaC during DNA replication gene gene1447 http://www.ncbi.nlm.nih.gov/gene/?term=spr1555 spr1556 spr1556 dnaB dnaB 1537088 1538257 - hypothetical protein gene gene1448 http://www.ncbi.nlm.nih.gov/gene/?term=spr1556 spr1557 spr1557 nrdR nrdR 1538258 1538731 - transcriptional regulator NrdR gene gene1449 http://www.ncbi.nlm.nih.gov/gene/?term=spr1557 spr1558 spr1558 spr1558 1538871 1539236 + hypothetical protein Similar to transcriptional regulator (GntR family) gene gene1450 http://www.ncbi.nlm.nih.gov/gene/?term=spr1558 spr1559 spr1559 ABC-NBD ABC-NBD 1539214 1539936 + ABC transporter ATP-binding protein gene gene1451 http://www.ncbi.nlm.nih.gov/gene/?term=spr1559 spr1560 spr1560 spr1560 1539872 1540720 + hypothetical protein gene gene1452 http://www.ncbi.nlm.nih.gov/gene/?term=spr1560 spr1561 spr1561 natB natB 1541133 1542332 - hypothetical protein gene gene1453 http://www.ncbi.nlm.nih.gov/gene/?term=spr1561 spr1562 spr1562 natA natA 1542329 1543222 - ABC transporter ATP-binding protein gene gene1454 http://www.ncbi.nlm.nih.gov/gene/?term=spr1562 spr1564 spr1564 spr1564 1544531 1545148 + hypothetical protein gene gene1455 http://www.ncbi.nlm.nih.gov/gene/?term=spr1564 spr1565 spr1565 scrK scrK 1545468 1546355 - fructokinase gene gene1456 http://www.ncbi.nlm.nih.gov/gene/?term=spr1565 spr1566 spr1566 scrA scrA 1546504 1548387 - PTS system transporter subunit IIABC gene gene1457 http://www.ncbi.nlm.nih.gov/gene/?term=spr1566 spr1568 spr1568 scrB scrB 1548764 1550218 + sucrose-6-phosphate hydrolase gene gene1458 http://www.ncbi.nlm.nih.gov/gene/?term=spr1568 spr1569 spr1569 scrR scrR 1550199 1551164 + sucrose operon repressor gene gene1459 http://www.ncbi.nlm.nih.gov/gene/?term=spr1569 spr1570 spr1570 mvaA mvaA 1551199 1552473 - 3-hydroxy-3-methylglutaryl-CoA reductase gene gene1460 http://www.ncbi.nlm.nih.gov/gene/?term=spr1570 spr1571 spr1571 mvaS mvaS 1552473 1553669 - hydroxymethylglutaryl-CoA synthase gene gene1461 http://www.ncbi.nlm.nih.gov/gene/?term=spr1571 spr1572 spr1572 spr1572 1553776 1554063 - hypothetical protein gene gene1462 http://www.ncbi.nlm.nih.gov/gene/?term=spr1572 spr1573 spr1573 IS1381 IS1381 1554092 1554481 - tranposase gene gene1463 http://www.ncbi.nlm.nih.gov/gene/?term=spr1573 spr1575 spr1575 spr1575 1554780 1555229 - hypothetical protein gene gene1464 http://www.ncbi.nlm.nih.gov/gene/?term=spr1575 spr1576 spr1576 spr1576 1555231 1555989 - hypothetical protein gene gene1465 http://www.ncbi.nlm.nih.gov/gene/?term=spr1576 spr1577 spr1577 pkn2 pkn2 1556104 1558083 - serine/threonine protein kinase gene gene1466 http://www.ncbi.nlm.nih.gov/gene/?term=spr1577 spr1578 spr1578 pppL pppL 1558080 1558820 - phosphatase gene gene1467 http://www.ncbi.nlm.nih.gov/gene/?term=spr1578 spr1579 spr1579 sunL sunL 1558835 1560151 - rRNA methylase gene gene1468 http://www.ncbi.nlm.nih.gov/gene/?term=spr1579 spr1580 spr1580 fmt fmt 1560141 1561076 - methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene1469 http://www.ncbi.nlm.nih.gov/gene/?term=spr1580 spr1581 spr1581 priA priA 1561089 1563485 - primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene1470 http://www.ncbi.nlm.nih.gov/gene/?term=spr1581 spr1582 spr1582 spr1582 1563551 1563865 - DNA-directed RNA polymerase subunit omega Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits gene gene1471 http://www.ncbi.nlm.nih.gov/gene/?term=spr1582 spr1583 spr1583 gmk gmk 1563890 1564516 - guanylate kinase Essential for recycling GMP and indirectly%2C cGMP gene gene1472 http://www.ncbi.nlm.nih.gov/gene/?term=spr1583 spr1584 spr1584 spr1584 1564646 1566259 - hypothetical protein gene gene1473 http://www.ncbi.nlm.nih.gov/gene/?term=spr1584 spr1585 spr1585 spr1585 1566450 1566704 - hypothetical protein gene gene1474 http://www.ncbi.nlm.nih.gov/gene/?term=spr1585 spr1586 spr1586 spr1586 1566708 1567001 - hypothetical protein gene gene1475 http://www.ncbi.nlm.nih.gov/gene/?term=spr1586 spr1587 spr1587 spr1587 1567200 1568297 - hypothetical protein gene gene1476 http://www.ncbi.nlm.nih.gov/gene/?term=spr1587 spr1588 spr1588 spr1588 1568307 1569053 - hypothetical protein gene gene1477 http://www.ncbi.nlm.nih.gov/gene/?term=spr1588 spr1589 spr1589 spr1589 1569156 1569509 - iojap-related protein gene gene1478 http://www.ncbi.nlm.nih.gov/gene/?term=spr1589 spr1590 spr1590 spr1590 1569522 1570022 - isochorismatase Similar to isochorismatase gene gene1479 http://www.ncbi.nlm.nih.gov/gene/?term=spr1590 spr1591 spr1591 spr1591 1570023 1570616 - hypothetical protein gene gene1480 http://www.ncbi.nlm.nih.gov/gene/?term=spr1591 spr1592 spr1592 nadD nadD 1570616 1571245 - nicotinic acid mononucleotide adenylyltransferase transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase%3B essential enzyme in bacteria gene gene1481 http://www.ncbi.nlm.nih.gov/gene/?term=spr1592 spr1593 spr1593 spr1593 1571297 1571608 - hypothetical protein gene gene1482 http://www.ncbi.nlm.nih.gov/gene/?term=spr1593 spr1594 spr1594 spr1594 1571823 1572929 - GTP-binding protein YqeH in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis gene gene1483 http://www.ncbi.nlm.nih.gov/gene/?term=spr1594 spr1595 spr1595 spr1595 1572932 1573522 - hypothetical protein gene gene1484 http://www.ncbi.nlm.nih.gov/gene/?term=spr1595 spr1596 spr1596 corA corA 1573474 1574370 - magnesium and cobalt transporter CorA gene gene1485 http://www.ncbi.nlm.nih.gov/gene/?term=spr1596 spr1597 spr1597 spr1597 1574427 1575032 - hypothetical protein gene gene1486 http://www.ncbi.nlm.nih.gov/gene/?term=spr1597 spr1598 spr1598 dctA dctA 1575376 1576335 + serine/threonine transporter SstT involved in the import of serine and threonine coupled with the import of sodium gene gene1487 http://www.ncbi.nlm.nih.gov/gene/?term=spr1598 spr1599 spr1599 spr1599 1576403 1577356 + hypothetical protein gene gene1488 http://www.ncbi.nlm.nih.gov/gene/?term=spr1599 spr1600 spr1600 spr1600 1577455 1577880 + transcriptional regulator Probable transcription regulator gene gene1489 http://www.ncbi.nlm.nih.gov/gene/?term=spr1600 spr1601 spr1601 spr1601 1577898 1578200 + hypothetical protein gene gene1490 http://www.ncbi.nlm.nih.gov/gene/?term=spr1601 spr1602 spr1602 trxA trxA 1578217 1578531 + thioredoxin gene gene1491 http://www.ncbi.nlm.nih.gov/gene/?term=spr1602 spr1603 spr1603 spr1603 1578797 1579369 + 7-cyano-7-deazaguanine reductase NADPH-dependent%3B catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis gene gene1492 http://www.ncbi.nlm.nih.gov/gene/?term=spr1603 spr1603a spr1603a spr1603a 1579381 1579824 + hypothetical protein gene gene1493 http://www.ncbi.nlm.nih.gov/gene/?term=spr1603a spr1604 spr1604 aqpZ aqpZ 1579849 1580517 - aquaporin gene gene1494 http://www.ncbi.nlm.nih.gov/gene/?term=spr1604 spr1605 spr1605 spr1605 1580628 1581188 - hypothetical protein gene gene1495 http://www.ncbi.nlm.nih.gov/gene/?term=spr1605 spr1606 spr1606 pepF pepF 1581428 1583224 - oligoendopeptidase F gene gene1496 http://www.ncbi.nlm.nih.gov/gene/?term=spr1606 spr1607 spr1607 spr1607 1583235 1583990 - 16S ribosomal RNA methyltransferase RsmE in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA%3B cells lacking this function can grow%2C but are outcompeted by wild-type%3B SAM-dependent m(3)U1498 methyltransferase gene gene1497 http://www.ncbi.nlm.nih.gov/gene/?term=spr1607 spr1608 spr1608 prmA prmA 1583980 1584930 - ribosomal protein L11 methyltransferase methylates ribosomal protein L11 at multiple amino acid positions%3B mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype gene gene1498 http://www.ncbi.nlm.nih.gov/gene/?term=spr1608 spr1609 spr1609 mutT mutT 1585068 1585496 - MutT/nudix family protein gene gene1499 http://www.ncbi.nlm.nih.gov/gene/?term=spr1609 spr1610 spr1610 spr1610 1585462 1586580 - hypothetical protein gene gene1500 http://www.ncbi.nlm.nih.gov/gene/?term=spr1610 spr1611 spr1611 spr1611 1586584 1587054 - hypothetical protein gene gene1501 http://www.ncbi.nlm.nih.gov/gene/?term=spr1611 spr1612 spr1612 spr1612 1587345 1587797 - hypothetical protein gene gene1502 http://www.ncbi.nlm.nih.gov/gene/?term=spr1612 spr1613 spr1613 spr1613 1587834 1588040 - hypothetical protein gene gene1503 http://www.ncbi.nlm.nih.gov/gene/?term=spr1613 spr1614 spr1614 spr1614 1588150 1588329 - hypothetical protein gene gene1504 http://www.ncbi.nlm.nih.gov/gene/?term=spr1614 spr1615 spr1615 spr1615 1588494 1588733 - hypothetical protein gene gene1505 http://www.ncbi.nlm.nih.gov/gene/?term=spr1615 spr1616 spr1616 cshA cshA 1589003 1590274 + recombination factor protein RarA gene gene1506 http://www.ncbi.nlm.nih.gov/gene/?term=spr1616 spr1617 spr1617 sacA sacA 1590821 1592140 - sucrose-6-phosphate hydrolase gene gene1508 http://www.ncbi.nlm.nih.gov/gene/?term=spr1617 spr1618 spr1618 ABC-MSP ABC-MSP 1592150 1593004 - sugar ABC transporter permease gene gene1509 http://www.ncbi.nlm.nih.gov/gene/?term=spr1618 spr1619 spr1619 ABC-MSP ABC-MSP 1592997 1593905 - sugar ABC transporter permease gene gene1510 http://www.ncbi.nlm.nih.gov/gene/?term=spr1619 spr1620 spr1620 ABC-SBP ABC-SBP 1593995 1595308 - sugar ABC transporter substrate-binding protein gene gene1511 http://www.ncbi.nlm.nih.gov/gene/?term=spr1620 spr1621 spr1621 scrR scrR 1595432 1596445 - sucrose operon repressor gene gene1512 http://www.ncbi.nlm.nih.gov/gene/?term=spr1621 spr1622 spr1622 spr1622 1596789 1598327 - hypothetical protein regulator protein gene gene1513 http://www.ncbi.nlm.nih.gov/gene/?term=spr1622 spr1623 spr1623 spr1623 1598954 1599526 + hypothetical protein gene gene1514 http://www.ncbi.nlm.nih.gov/gene/?term=spr1623 spr1624 spr1624 spr1624 1599538 1599708 + hypothetical protein gene gene1515 http://www.ncbi.nlm.nih.gov/gene/?term=spr1624 spr1625 spr1625 spr1625 1599747 1600355 + general stress protein 24 gene gene1516 http://www.ncbi.nlm.nih.gov/gene/?term=spr1625 spr1626 spr1626 spr1626 1600386 1600589 + hypothetical protein gene gene1517 http://www.ncbi.nlm.nih.gov/gene/?term=spr1626 spr1627 spr1627 spr1627 1601116 1601562 - hypothetical protein Probable acetyltransferase gene gene1518 http://www.ncbi.nlm.nih.gov/gene/?term=spr1627 spr1628 spr1628 pilD pilD 1601632 1602291 + type IV prepilin peptidase gene gene1519 http://www.ncbi.nlm.nih.gov/gene/?term=spr1628 spr1629 spr1629 spr1629 1602343 1603494 - transcriptional regulator DNA-binding protein gene gene1520 http://www.ncbi.nlm.nih.gov/gene/?term=spr1629 spr1630 spr1630 spr1630 1603509 1604240 - hypothetical protein gene gene1521 http://www.ncbi.nlm.nih.gov/gene/?term=spr1630 spr1631 spr1631 trpA trpA 1604542 1605318 - tryptophan synthase subunit alpha catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis gene gene1522 http://www.ncbi.nlm.nih.gov/gene/?term=spr1631 spr1632 spr1632 trpB trpB 1605311 1606534 - tryptophan synthase subunit beta catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate gene gene1523 http://www.ncbi.nlm.nih.gov/gene/?term=spr1632 spr1633 spr1633 trpF trpF 1606512 1607141 - N-(5'-phosphoribosyl)anthranilate isomerase catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis gene gene1524 http://www.ncbi.nlm.nih.gov/gene/?term=spr1633 spr1634 spr1634 trpC trpC 1607098 1607865 - indole-3-glycerol phosphate synthase involved in tryptophan biosynthesis%3B amino acid biosynthesis%3B converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water gene gene1525 http://www.ncbi.nlm.nih.gov/gene/?term=spr1634 spr1635 spr1635 trpD trpD 1607862 1608866 - anthranilate phosphoribosyltransferase Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene1526 http://www.ncbi.nlm.nih.gov/gene/?term=spr1635 spr1636 spr1636 trpG trpG 1608877 1609443 - anthranilate synthase component II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene1527 http://www.ncbi.nlm.nih.gov/gene/?term=spr1636 spr1637 spr1637 trpE trpE 1609440 1610801 - anthranilate synthase component I with component II%2C the glutamine amidotransferase%2C catalyzes the formation of anthranilate from chorismate and glutamine gene gene1528 http://www.ncbi.nlm.nih.gov/gene/?term=spr1637 spr1639 spr1639 ccpA ccpA 1611988 1612989 - catabolite control protein gene gene1529 http://www.ncbi.nlm.nih.gov/gene/?term=spr1639 spr1640 spr1640 spr1640 1613097 1613465 - hypothetical protein gene gene1530 http://www.ncbi.nlm.nih.gov/gene/?term=spr1640 spr1641 spr1641 mgtC mgtC 1613561 1614271 - Mg2+ transporter gene gene1531 http://www.ncbi.nlm.nih.gov/gene/?term=spr1641 spr1643 spr1643 ABC-MSP ABC-MSP 1614274 1615965 - ABC transporter permease gene gene1532 http://www.ncbi.nlm.nih.gov/gene/?term=spr1643 spr1644 spr1644 ABC-NBD ABC-NBD 1615977 1616987 - ABC transporter ATP-binding protein gene gene1533 http://www.ncbi.nlm.nih.gov/gene/?term=spr1644 spr1645 spr1645 ABC-SBP ABC-SBP 1617090 1618157 - ABC transporter substrate-binding protein gene gene1534 http://www.ncbi.nlm.nih.gov/gene/?term=spr1645 spr1646 spr1646 spr1646 1618182 1618841 - hypothetical protein gene gene1535 http://www.ncbi.nlm.nih.gov/gene/?term=spr1646 spr1647 spr1647 galE galE 1619051 1620031 - UDP-glucose 4-epimerase gene gene1536 http://www.ncbi.nlm.nih.gov/gene/?term=spr1647 spr1648 spr1648 galT galT 1620044 1621519 - galactose-1-phosphate uridylyltransferase catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism gene gene1537 http://www.ncbi.nlm.nih.gov/gene/?term=spr1648 spr1649 spr1649 spr1649 1621532 1622173 - phosphate transporter PhoU transcriptional regulator (phoU like) gene gene1538 http://www.ncbi.nlm.nih.gov/gene/?term=spr1649 spr1650 spr1650 spr1650 1622231 1623082 - gene gene1539 http://www.ncbi.nlm.nih.gov/gene/?term=spr1650 spr1652 spr1652 spr1652 1623066 1625225 - cell wall surface anchor family protein gene gene1540 http://www.ncbi.nlm.nih.gov/gene/?term=spr1652 spr1654 spr1654 spr1654 1626356 1627609 - capsular polysaccharide biosynthesis protein role in biosynthesis of amino sugar gene gene1541 http://www.ncbi.nlm.nih.gov/gene/?term=spr1654 spr1655 spr1655 spr1655 1627625 1628356 - glycosyl transferase glycosyltransferase gene gene1542 http://www.ncbi.nlm.nih.gov/gene/?term=spr1655 spr1656 spr1656 ABC-N/P ABC-N/P 1628490 1630241 - ABC transporter ATP-binding protein/permease gene gene1543 http://www.ncbi.nlm.nih.gov/gene/?term=spr1656 spr1657 spr1657 ABC-N/P ABC-N/P 1630231 1632015 - ABC transporter ATP-binding protein/permease gene gene1544 http://www.ncbi.nlm.nih.gov/gene/?term=spr1657 spr1659 spr1659 spr1659 1632631 1633087 - gene gene1545 http://www.ncbi.nlm.nih.gov/gene/?term=spr1659 spr1660 spr1660 exoA exoA 1633221 1634048 + exodeoxyribonuclease gene gene1546 http://www.ncbi.nlm.nih.gov/gene/?term=spr1660 spr1661 spr1661 spr1661 1634203 1634442 + hypothetical protein gene gene1547 http://www.ncbi.nlm.nih.gov/gene/?term=spr1661 spr1662 spr1662 xpt xpt 1635320 1635901 + xanthine phosphoribosyltransferase Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine gene gene1548 http://www.ncbi.nlm.nih.gov/gene/?term=spr1662 spr1663 spr1663 pbuX pbuX 1635901 1637163 + xanthine permease gene gene1549 http://www.ncbi.nlm.nih.gov/gene/?term=spr1663 spr1664 spr1664 dpnD dpnD 1637214 1637675 - hypothetical protein gene gene1550 http://www.ncbi.nlm.nih.gov/gene/?term=spr1664 spr1665 spr1665 dpnC dpnC 1637672 1638436 - type II restriction enzyme DpnI (dpnC) gene gene1551 http://www.ncbi.nlm.nih.gov/gene/?term=spr1665 spr1666 spr1666 spr1666 1638617 1639042 - hypothetical protein Similar to E. coli PaaI protein involved in phenylacetic acid degradation gene gene1552 http://www.ncbi.nlm.nih.gov/gene/?term=spr1666 spr1667 spr1667 galT galT 1639091 1640572 - galactose-1-phosphate uridylyltransferase catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism gene gene1553 http://www.ncbi.nlm.nih.gov/gene/?term=spr1667 spr1668 spr1668 galK galK 1640591 1641769 - galactokinase catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism gene gene1554 http://www.ncbi.nlm.nih.gov/gene/?term=spr1668 spr1669 spr1669 galR galR 1641933 1642940 + regulator of gal operon GalR gene gene1555 http://www.ncbi.nlm.nih.gov/gene/?term=spr1669 spr1670 spr1670 adhB adhB 1642986 1644023 - zinc-containing alcohol dehydrogenase gene gene1556 http://www.ncbi.nlm.nih.gov/gene/?term=spr1670 spr1671 spr1671 spr1671 1644024 1644377 - hypothetical protein Similar to transcriptional regulator (MerR family) gene gene1557 http://www.ncbi.nlm.nih.gov/gene/?term=spr1671 spr1672 spr1672 czcD czcD 1644621 1645520 - cation efflux system protein gene gene1558 http://www.ncbi.nlm.nih.gov/gene/?term=spr1672 spr1673 spr1673 spr1673 1645644 1646180 + hypothetical protein tetR-family transcriptional regulator gene gene1559 http://www.ncbi.nlm.nih.gov/gene/?term=spr1673 spr1674 spr1674 spr1674 1646347 1647156 - hypothetical protein gene gene1560 http://www.ncbi.nlm.nih.gov/gene/?term=spr1674 spr1675 spr1675 IS1167 IS1167 1647556 1648074 + transposase gene gene1561 http://www.ncbi.nlm.nih.gov/gene/?term=spr1675 spr1677 spr1677 proWX proWX 1648982 1650502 - choline ABC transporter permease gene gene1562 http://www.ncbi.nlm.nih.gov/gene/?term=spr1677 spr1678 spr1678 proV proV 1650495 1651223 - choline transporter gene gene1563 http://www.ncbi.nlm.nih.gov/gene/?term=spr1678 spr1679 spr1679 spr1679 1651238 1652002 - hypothetical protein gene gene1564 http://www.ncbi.nlm.nih.gov/gene/?term=spr1679 spr1680 spr1680 spr1680 1652006 1652449 - hypothetical protein transcriptional regulator gene gene1565 http://www.ncbi.nlm.nih.gov/gene/?term=spr1680 spr1681 spr1681 spr1681 1653131 1653436 - hypothetical protein gene gene1566 http://www.ncbi.nlm.nih.gov/gene/?term=spr1681 spr1682 spr1682 pepA pepA 1653449 1654513 - glutamyl aminopeptidase gene gene1567 http://www.ncbi.nlm.nih.gov/gene/?term=spr1682 spr1683 spr1683 spr1683 1654914 1655615 + NAD-dependent epimerase/dehydratase gene gene1568 http://www.ncbi.nlm.nih.gov/gene/?term=spr1683 spr1684 spr1684 fatD fatD 1656023 1656997 + iron-compound ABC transporter permease gene gene1569 http://www.ncbi.nlm.nih.gov/gene/?term=spr1684 spr1685 spr1685 fatC fatC 1656987 1657943 + iron-compound ABC transporter permease gene gene1570 http://www.ncbi.nlm.nih.gov/gene/?term=spr1685 spr1686 spr1686 fecE fecE 1657940 1658692 + iron-compound ABC transporter ATP-binding protein gene gene1571 http://www.ncbi.nlm.nih.gov/gene/?term=spr1686 spr1687 spr1687 fatB fatB 1658788 1659753 + iron-compound ABC transporter substrate-binding protein gene gene1572 http://www.ncbi.nlm.nih.gov/gene/?term=spr1687 spr1688 spr1688 spr1688 1659978 1660220 - hypothetical protein gene gene1573 http://www.ncbi.nlm.nih.gov/gene/?term=spr1688 spr1689 spr1689 rluB rluB 1660220 1660942 - ribosomal large subunit pseudouridine synthase B gene gene1574 http://www.ncbi.nlm.nih.gov/gene/?term=spr1689 spr1690 spr1690 scpB scpB 1660929 1661498 - segregation and condensation protein B functions during chromosome segregation%3B may form a condensin-like structure with SMC and ScpA%3B forms a homodimer gene gene1575 http://www.ncbi.nlm.nih.gov/gene/?term=spr1690 spr1691 spr1691 scpA scpA 1661517 1662245 - segregation and condensation protein A functions during chromosome segregation%3B may form a condensin-like structure with SMC and ScpB gene gene1576 http://www.ncbi.nlm.nih.gov/gene/?term=spr1691 spr1692 spr1692 xerD xerD 1662245 1662985 - site-specific tyrosine recombinase XerD-like protein site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B forms a heterotetrameric complex with XerC%3B XerCD exhibit similar sequences%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerCD complex%3B enzyme from Streptococcus group has unusual active site motifs gene gene1577 http://www.ncbi.nlm.nih.gov/gene/?term=spr1692 spr1693 spr1693 spr1693 1662976 1663437 - hypothetical protein gene gene1578 http://www.ncbi.nlm.nih.gov/gene/?term=spr1693 spr1694 spr1694 spr1694 1663434 1663955 - hypothetical protein gene gene1579 http://www.ncbi.nlm.nih.gov/gene/?term=spr1694 spr1695 spr1695 spr1695 1663931 1664902 - fused deoxyribonucleotide triphosphate pyrophosphatase/hypothetical protein HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine gene gene1580 http://www.ncbi.nlm.nih.gov/gene/?term=spr1695 spr1696 spr1696 murI murI 1664899 1665693 - glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene1581 http://www.ncbi.nlm.nih.gov/gene/?term=spr1696 spr1697 spr1697 spr1697 1665900 1666202 - hypothetical protein gene gene1582 http://www.ncbi.nlm.nih.gov/gene/?term=spr1697 spr1698 spr1698 dexS dexS 1666290 1667915 - dextran glucosidase Also highly similar to trehalose-6-phosphate hydrolase gene gene1583 http://www.ncbi.nlm.nih.gov/gene/?term=spr1698 spr1699 spr1699 treP treP 1668093 1670210 - PTS system trehalose-specific transporter subunit IIBC gene gene1584 http://www.ncbi.nlm.nih.gov/gene/?term=spr1699 spr1700 spr1700 treR treR 1670245 1670955 + trehalose operon transcriptional repressor gene gene1585 http://www.ncbi.nlm.nih.gov/gene/?term=spr1700 spr1703 spr1703 amiF amiF 1672492 1673463 - oligopeptide ABC transporter ATP-binding protein AmiF gene gene1586 http://www.ncbi.nlm.nih.gov/gene/?term=spr1703 spr1704 spr1704 amiE amiE 1673429 1674496 - oligopeptide ABC transporter ATP-binding protein AmiE gene gene1587 http://www.ncbi.nlm.nih.gov/gene/?term=spr1704 spr1705 spr1705 amiD amiD 1674505 1675431 - oligopeptide ABC transporter permease AmiD gene gene1588 http://www.ncbi.nlm.nih.gov/gene/?term=spr1705 spr1706 spr1706 amiC amiC 1675431 1676927 - oligopeptide ABC transporter permease AmiC gene gene1589 http://www.ncbi.nlm.nih.gov/gene/?term=spr1706 spr1707 spr1707 amiA amiA 1676994 1678973 - oligopeptide ABC transporter substrate-binding protein gene gene1590 http://www.ncbi.nlm.nih.gov/gene/?term=spr1707 spr1708 spr1708 spr1708 1679660 1680853 - hypothetical protein gene gene1591 http://www.ncbi.nlm.nih.gov/gene/?term=spr1708 spr1709 spr1709 gtfA gtfA 1680991 1682433 - sucrose phosphorylase gene gene1592 http://www.ncbi.nlm.nih.gov/gene/?term=spr1709 spr1709a spr1709a spr1709a 1682617 1682784 - hypothetical protein gene gene1593 http://www.ncbi.nlm.nih.gov/gene/?term=spr1709a spr1710 spr1710 msmG msmG 1682791 1683624 - sugar ABC transporter permease gene gene1594 http://www.ncbi.nlm.nih.gov/gene/?term=spr1710 spr1711 spr1711 msmF msmF 1683638 1684528 - sugar ABC transporter permease gene gene1595 http://www.ncbi.nlm.nih.gov/gene/?term=spr1711 spr1712 spr1712 msmE msmE 1684518 1685777 - sugar ABC transporter substrate-binding protein gene gene1596 http://www.ncbi.nlm.nih.gov/gene/?term=spr1712 spr1713 spr1713 aga aga 1685869 1688031 - alpha-galactosidase gene gene1597 http://www.ncbi.nlm.nih.gov/gene/?term=spr1713 spr1714 spr1714 msmR msmR 1688139 1688999 + MSM (multiple sugar metabolism) operon regulatory protein gene gene1598 http://www.ncbi.nlm.nih.gov/gene/?term=spr1714 spr1715 spr1715 birA birA 1688996 1689931 + biotin--protein ligase catalyzes the formation of biotinyl-5'-AMP%2C also acts as a transcriptional repressor of the biotin operon gene gene1599 http://www.ncbi.nlm.nih.gov/gene/?term=spr1715 spr1717 spr1717 spr1717 1697564 1698919 - hypothetical protein Similar to RNA methyltransferase gene gene1622 http://www.ncbi.nlm.nih.gov/gene/?term=spr1717 spr1718 spr1718 recX recX 1698957 1699733 + recombination regulator RecX binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities gene gene1623 http://www.ncbi.nlm.nih.gov/gene/?term=spr1718 spr1719 spr1719 spr1719 1699822 1700355 + hypothetical protein gene gene1624 http://www.ncbi.nlm.nih.gov/gene/?term=spr1719 spr1720 spr1720 spr1720 1700709 1700915 - hypothetical protein gene gene1625 http://www.ncbi.nlm.nih.gov/gene/?term=spr1720 spr1721 spr1721 spr1721 1701075 1702304 + transposase gene gene1626 http://www.ncbi.nlm.nih.gov/gene/?term=spr1721 spr1722 spr1722 groEL groEL 1702403 1704025 - molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene1627 http://www.ncbi.nlm.nih.gov/gene/?term=spr1722 spr1723 spr1723 groES groES 1704041 1704325 - co-chaperonin GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene1628 http://www.ncbi.nlm.nih.gov/gene/?term=spr1723 spr1724 spr1724 ssbB ssbB 1704481 1704876 - single-stranded DNA-binding protein binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA gene gene1629 http://www.ncbi.nlm.nih.gov/gene/?term=spr1724 spr1725 spr1725 ydfG ydfG 1704954 1705715 - oxidoreductase gene gene1630 http://www.ncbi.nlm.nih.gov/gene/?term=spr1725 spr1726 spr1726 spr1726 1705748 1706374 - hypothetical protein gene gene1631 http://www.ncbi.nlm.nih.gov/gene/?term=spr1726 spr1727 spr1727 spr1727 1706390 1706707 - hypothetical protein Similar to thioredoxin H1 gene gene1632 http://www.ncbi.nlm.nih.gov/gene/?term=spr1727 spr1728 spr1728 spr1728 1706704 1707003 - hypothetical protein gene gene1633 http://www.ncbi.nlm.nih.gov/gene/?term=spr1728 spr1730 spr1730 spr1730 1707692 1708366 - hypothetical protein gene gene1634 http://www.ncbi.nlm.nih.gov/gene/?term=spr1730 spr1731 spr1731 spr1731 1708372 1708821 - hypothetical protein gene gene1635 http://www.ncbi.nlm.nih.gov/gene/?term=spr1731 spr1732 spr1732 spr1732 1708932 1709435 - PAP2 family protein Similar to bacteriocin transport permease gene gene1636 http://www.ncbi.nlm.nih.gov/gene/?term=spr1732 spr1733 spr1733 spr1733 1709432 1709794 - hypothetical protein gene gene1637 http://www.ncbi.nlm.nih.gov/gene/?term=spr1733 spr1734 spr1734 spr1734 1709860 1710891 - ABC transporter ATP-binding protein gene gene1638 http://www.ncbi.nlm.nih.gov/gene/?term=spr1734 spr1735 spr1735 ABC-NBD-truncation ABC-NBD-truncation 1710898 1711719 - gene gene1639 http://www.ncbi.nlm.nih.gov/gene/?term=spr1735 spr1737 spr1737 spr1737 1711758 1712205 - gene gene1640 http://www.ncbi.nlm.nih.gov/gene/?term=spr1737 spr1738 spr1738 spr1738 1712329 1713045 - hypothetical protein gene gene1641 http://www.ncbi.nlm.nih.gov/gene/?term=spr1738 spr1739 spr1739 ply ply 1713926 1715341 - pneumolysin gene gene1642 http://www.ncbi.nlm.nih.gov/gene/?term=spr1739 spr1740 spr1740 spr1740 1715352 1715762 - hypothetical protein gene gene1643 http://www.ncbi.nlm.nih.gov/gene/?term=spr1740 spr1741 spr1741 spr1741 1715755 1716363 - hypothetical protein gene gene1644 http://www.ncbi.nlm.nih.gov/gene/?term=spr1741 spr1742 spr1742 spr1742 1716376 1716833 - gene gene1645 http://www.ncbi.nlm.nih.gov/gene/?term=spr1742 spr1746 spr1746 spr1746 1718122 1718382 - hypothetical protein gene gene1646 http://www.ncbi.nlm.nih.gov/gene/?term=spr1746 spr1747 spr1747 spr1747 1718441 1718995 - hypothetical protein gene gene1647 http://www.ncbi.nlm.nih.gov/gene/?term=spr1747 spr1748 spr1748 spr1748 1718982 1719179 - hypothetical protein gene gene1648 http://www.ncbi.nlm.nih.gov/gene/?term=spr1748 spr1749 spr1749 spr1749 1719183 1719977 - hypothetical protein gene gene1649 http://www.ncbi.nlm.nih.gov/gene/?term=spr1749 spr1750 spr1750 spr1750 1720262 1720810 - gene gene1650 http://www.ncbi.nlm.nih.gov/gene/?term=spr1750 spr1751 spr1751 spr1751 1720939 1721298 - hypothetical protein gene gene1651 http://www.ncbi.nlm.nih.gov/gene/?term=spr1751 spr1752 spr1752 spr1752 1721344 1721586 - hypothetical protein gene gene1652 http://www.ncbi.nlm.nih.gov/gene/?term=spr1752 spr1753 spr1753 spr1753 1721537 1721710 - hypothetical protein gene gene1653 http://www.ncbi.nlm.nih.gov/gene/?term=spr1753 spr1754 spr1754 lytA lytA 1722069 1723025 - N-acetylmuramoyl-L-alanine amidase gene gene1654 http://www.ncbi.nlm.nih.gov/gene/?term=spr1754 spr1756 spr1756 dinF dinF 1723401 1724771 - MATE efflux family protein DinF gene gene1655 http://www.ncbi.nlm.nih.gov/gene/?term=spr1756 spr1757 spr1757 recA recA 1725078 1726244 - recombinase A catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene1656 http://www.ncbi.nlm.nih.gov/gene/?term=spr1757 spr1758 spr1758 cinA cinA 1726299 1727555 - competence damage-inducible protein A Competence induced protein A gene gene1657 http://www.ncbi.nlm.nih.gov/gene/?term=spr1758 spr1759 spr1759 lytR lytR 1727640 1728656 - transcriptional regulator gene gene1658 http://www.ncbi.nlm.nih.gov/gene/?term=spr1759 spr1760 spr1760 spr1760 1728664 1729182 - hypothetical protein gene gene1659 http://www.ncbi.nlm.nih.gov/gene/?term=spr1760 spr1761 spr1761 spr1761 1729172 1729615 - hypothetical protein gene gene1660 http://www.ncbi.nlm.nih.gov/gene/?term=spr1761 spr1762 spr1762 spr1762 1729701 1730321 - hypothetical protein gene gene1661 http://www.ncbi.nlm.nih.gov/gene/?term=spr1762 spr1763 spr1763 plcR plcR 1730704 1731567 - transcriptional activator gene gene1662 http://www.ncbi.nlm.nih.gov/gene/?term=spr1763 spr1764 spr1764 spr1764 1731759 1731929 + hypothetical protein gene gene1663 http://www.ncbi.nlm.nih.gov/gene/?term=spr1764 spr1765 spr1765 spr1765 1732032 1732256 + hypothetical protein gene gene1664 http://www.ncbi.nlm.nih.gov/gene/?term=spr1765 spr1766 spr1766 spr1766 1732263 1732451 + hypothetical protein gene gene1665 http://www.ncbi.nlm.nih.gov/gene/?term=spr1766 spr1767 spr1767 cylM cylM 1732567 1735557 + bacteriocin formation protein gene gene1666 http://www.ncbi.nlm.nih.gov/gene/?term=spr1767 spr1768 spr1768 spr1768 1735907 1736611 + hypothetical protein Related to Trp repressor binding protein gene gene1667 http://www.ncbi.nlm.nih.gov/gene/?term=spr1768 spr1769 spr1769 spr1769 1736592 1737521 + hypothetical protein gene gene1668 http://www.ncbi.nlm.nih.gov/gene/?term=spr1769 spr1770 spr1770 clyB clyB 1737518 1739626 + toxin secretion ABC transporter ATP-binding/permease gene gene1669 http://www.ncbi.nlm.nih.gov/gene/?term=spr1770 spr1771 spr1771 nisP nisP 1739650 1741389 + subtilisin-like serine protease gene gene1670 http://www.ncbi.nlm.nih.gov/gene/?term=spr1771 spr1772 spr1772 spr1772 1741440 1742207 + hypothetical protein gene gene1671 http://www.ncbi.nlm.nih.gov/gene/?term=spr1772 spr1773 spr1773 ABC-NBD ABC-NBD 1742209 1742841 + ABC transporter ATP-binding protein gene gene1672 http://www.ncbi.nlm.nih.gov/gene/?term=spr1773 spr1774 spr1774 spr1774 1742999 1743277 + gene gene1673 http://www.ncbi.nlm.nih.gov/gene/?term=spr1774 spr1775 spr1775 ndk ndk 1743787 1744200 - nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene1674 http://www.ncbi.nlm.nih.gov/gene/?term=spr1775 spr1776 spr1776 rpoC rpoC 1744311 1747988 - DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene1675 http://www.ncbi.nlm.nih.gov/gene/?term=spr1776 spr1777 spr1777 rpoB rpoB 1748021 1751671 - DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene1676 http://www.ncbi.nlm.nih.gov/gene/?term=spr1777 spr1778 spr1778 hlyX hlyX 1752316 1753647 - hemolysin gene gene1678 http://www.ncbi.nlm.nih.gov/gene/?term=spr1778 spr1779 spr1779 endA endA 1753876 1754700 - DNA-entry nuclease gene gene1679 http://www.ncbi.nlm.nih.gov/gene/?term=spr1779 spr1780 spr1780 epuA epuA 1754739 1754945 - hypothetical protein gene gene1680 http://www.ncbi.nlm.nih.gov/gene/?term=spr1780 spr1781 spr1781 murA murA 1754920 1756203 - UDP-N-acetylglucosamine 1-carboxyvinyltransferase adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation%3B gram-positive bacteria have 2 copies of MurA which are active gene gene1681 http://www.ncbi.nlm.nih.gov/gene/?term=spr1781 spr1781a spr1781a spr1781a 1756227 1756457 - hypothetical protein gene gene1682 http://www.ncbi.nlm.nih.gov/gene/?term=spr1781a spr1782 spr1782 spr1782 1756515 1757552 - hypothetical protein gene gene1683 http://www.ncbi.nlm.nih.gov/gene/?term=spr1782 spr1783 spr1783 coaD coaD 1757536 1758024 - phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene1684 http://www.ncbi.nlm.nih.gov/gene/?term=spr1783 spr1784 spr1784 spr1784 1758014 1758553 - type II DNA modification methyltransferase Probable methylase gene gene1685 http://www.ncbi.nlm.nih.gov/gene/?term=spr1784 spr1785 spr1785 asnA asnA 1758618 1759616 - asparagine synthetase AsnA catalyzes the formation of asparagine from aspartate and ammonia gene gene1686 http://www.ncbi.nlm.nih.gov/gene/?term=spr1785 spr1787 spr1787 spr1787 1759722 1760429 - hypothetical protein transmembrane protein gene gene1687 http://www.ncbi.nlm.nih.gov/gene/?term=spr1787 spr1788 spr1788 yjfA yjfA 1760461 1761219 - rRNA/tRNA methylase gene gene1688 http://www.ncbi.nlm.nih.gov/gene/?term=spr1788 spr1789 spr1789 acyP acyP 1761235 1761513 + acylphosphatase catalyzes the hydrolysis of acylphosphate gene gene1689 http://www.ncbi.nlm.nih.gov/gene/?term=spr1789 spr1790 spr1790 spr1790 1761591 1762517 + OxaA-like protein involved in biogenesis of membrane proteins%3B Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site gene gene1690 http://www.ncbi.nlm.nih.gov/gene/?term=spr1790 spr1791 spr1791 pflC pflC 1762592 1763386 - pyruvate-formate lyase activating enzyme gene gene1691 http://www.ncbi.nlm.nih.gov/gene/?term=spr1791 spr1792 spr1792 lysA lysA 1763512 1764762 - diaminopimelate decarboxylase gene gene1692 http://www.ncbi.nlm.nih.gov/gene/?term=spr1792 spr1793 spr1793 purR purR 1764829 1765656 - pur operon repressor gene gene1693 http://www.ncbi.nlm.nih.gov/gene/?term=spr1793 spr1794 spr1794 cbf1 cbf1 1765923 1766927 - cmp-binding-factor 1 gene gene1694 http://www.ncbi.nlm.nih.gov/gene/?term=spr1794 spr1795 spr1795 spr1795 1766854 1768152 - hypothetical protein gene gene1695 http://www.ncbi.nlm.nih.gov/gene/?term=spr1795 spr1796 spr1796 spr1796 1768112 1768795 - hypothetical protein gene gene1696 http://www.ncbi.nlm.nih.gov/gene/?term=spr1796 spr1797 spr1797 rpe rpe 1768737 1769393 - ribulose-phosphate 3-epimerase gene gene1697 http://www.ncbi.nlm.nih.gov/gene/?term=spr1797 spr1798 spr1798 spr1798 1769404 1770282 - ribosome-associated GTPase EngC%3B RsgA%3B CpgA%3B circularly permuted GTPase%3B ribosome small subunit-dependent GTPase A%3B has the pattern G4-G1-G3 as opposed to other GTPases%3B interacts strongly with 30S ribosome which stimulates GTPase activity gene gene1698 http://www.ncbi.nlm.nih.gov/gene/?term=spr1798 spr1799 spr1799 ksgA ksgA 1770284 1771156 - dimethyladenosine transferase catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin gene gene1699 http://www.ncbi.nlm.nih.gov/gene/?term=spr1799 spr1800 spr1800 spr1800 1771287 1771601 - hypothetical protein gene gene1700 http://www.ncbi.nlm.nih.gov/gene/?term=spr1800 spr1801 spr1801 ABC-NBD ABC-NBD 1771588 1772229 - ABC transporter ATP-binding protein gene gene1701 http://www.ncbi.nlm.nih.gov/gene/?term=spr1801 spr1802 spr1802 spr1802 1772231 1774273 - hypothetical protein immunity protein gene gene1702 http://www.ncbi.nlm.nih.gov/gene/?term=spr1802 spr1803 spr1803 plcR plcR 1774530 1775429 - transcriptional regulator PlcR gene gene1703 http://www.ncbi.nlm.nih.gov/gene/?term=spr1803 spr1804 spr1804 spr1804 1775501 1776061 - primase-related protein Primase-related protein gene gene1704 http://www.ncbi.nlm.nih.gov/gene/?term=spr1804 spr1805 spr1805 spr1805 1776061 1776834 - hypothetical protein gene gene1705 http://www.ncbi.nlm.nih.gov/gene/?term=spr1805 spr1806 spr1806 spr1806 1777140 1777805 - cell wall surface anchor family protein gene gene1706 http://www.ncbi.nlm.nih.gov/gene/?term=spr1806 spr1807 spr1807 rpmH rpmH 1778068 1778202 - 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene1707 http://www.ncbi.nlm.nih.gov/gene/?term=spr1807 spr1808 spr1808 aspC aspC 1778347 1779561 - aminotransferase broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor gene gene1708 http://www.ncbi.nlm.nih.gov/gene/?term=spr1808 spr1809 spr1809 spr1809 1779717 1780025 - hypothetical protein gene gene1709 http://www.ncbi.nlm.nih.gov/gene/?term=spr1809 spr1810 spr1810 spr1810 1780109 1780624 + hypothetical protein gene gene1710 http://www.ncbi.nlm.nih.gov/gene/?term=spr1810 spr1811 spr1811 spr1811 1780659 1782077 - Cof family protein gene gene1711 http://www.ncbi.nlm.nih.gov/gene/?term=spr1811 spr1812 spr1812 ansB ansB 1782113 1783075 + L-asparaginase gene gene1712 http://www.ncbi.nlm.nih.gov/gene/?term=spr1812 spr1812a spr1812a spr1812a 1783072 1783263 - hypothetical protein gene gene1713 http://www.ncbi.nlm.nih.gov/gene/?term=spr1812a spr1813 spr1813 ccpA ccpA 1783327 1784367 - catabolite control protein A gene gene1714 http://www.ncbi.nlm.nih.gov/gene/?term=spr1813 spr1814 spr1814 rr11 rr11 1784762 1785361 - DNA-binding response regulator gene gene1715 http://www.ncbi.nlm.nih.gov/gene/?term=spr1814 spr1815 spr1815 hk11 hk11 1785363 1786460 - sensor histidine kinase gene gene1716 http://www.ncbi.nlm.nih.gov/gene/?term=spr1815 spr1816 spr1816 spr1816 1786460 1787227 - hypothetical protein gene gene1717 http://www.ncbi.nlm.nih.gov/gene/?term=spr1816 spr1817 spr1817 ABC-NBD ABC-NBD 1787199 1788083 - ABC transporter ATP-binding protein gene gene1718 http://www.ncbi.nlm.nih.gov/gene/?term=spr1817 spr1818 spr1818 spr1818 1788261 1788467 - hypothetical protein gene gene1719 http://www.ncbi.nlm.nih.gov/gene/?term=spr1818 spr1819 spr1819 comX2 comX2 1795146 1795625 - competence-specific global transcription modulator sigma factor gene gene1734 http://www.ncbi.nlm.nih.gov/gene/?term=spr1819 spr1820 spr1820 nusG nusG 1795747 1796298 - transcription antitermination protein NusG Modulates Rho-dependent transcription termination gene gene1735 http://www.ncbi.nlm.nih.gov/gene/?term=spr1820 spr1821 spr1821 secE secE 1796338 1796514 - preprotein translocase subunit SecE forms a complex with SecY and SecG%3B SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force gene gene1736 http://www.ncbi.nlm.nih.gov/gene/?term=spr1821 spr1822 spr1822 rpmG rpmG 1796524 1796676 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group have the CXXC motif gene gene1737 http://www.ncbi.nlm.nih.gov/gene/?term=spr1822 spr1823 spr1823 pbp2a pbp2a 1796729 1798924 - penicillin-binding protein 2A gene gene1738 http://www.ncbi.nlm.nih.gov/gene/?term=spr1823 spr1824 spr1824 rluD rluD 1799011 1799886 + ribosomal large subunit pseudouridine synthase D gene gene1739 http://www.ncbi.nlm.nih.gov/gene/?term=spr1824 spr1825 spr1825 gapA gapA 1799954 1801033 - glyceraldehyde-3-phosphate dehydrogenase catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate gene gene1740 http://www.ncbi.nlm.nih.gov/gene/?term=spr1825 spr1826 spr1826 spr1826 1801138 1802118 - hypothetical protein gene gene1741 http://www.ncbi.nlm.nih.gov/gene/?term=spr1826 spr1828 spr1828 transposase_A transposase_A 1802664 1803011 - transposase gene gene1742 http://www.ncbi.nlm.nih.gov/gene/?term=spr1828 spr1829 spr1829 nadC nadC 1803124 1804023 - nicotinate-nucleotide pyrophosphorylase catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene1743 http://www.ncbi.nlm.nih.gov/gene/?term=spr1829 spr1830 spr1830 spr1830 1804233 1805543 + hypothetical protein integral membrane protein gene gene1744 http://www.ncbi.nlm.nih.gov/gene/?term=spr1830 spr1831 spr1831 spr1831 1805909 1806103 - hypothetical protein gene gene1745 http://www.ncbi.nlm.nih.gov/gene/?term=spr1831 spr1832 spr1832 spr1832 1806563 1807291 - hypothetical protein transcription regulator gene gene1746 http://www.ncbi.nlm.nih.gov/gene/?term=spr1832 spr1833 spr1833 bgl2 bgl2 1807407 1808858 + beta-glucosidase gene gene1747 http://www.ncbi.nlm.nih.gov/gene/?term=spr1833 spr1834 spr1834 ptcC ptcC 1808876 1810171 + PTS system transporter subunit IIC gene gene1748 http://www.ncbi.nlm.nih.gov/gene/?term=spr1834 spr1835 spr1835 ptcB ptcB 1810176 1810484 + PTS system transporter subunit IIB gene gene1749 http://www.ncbi.nlm.nih.gov/gene/?term=spr1835 spr1836 spr1836 ptcA ptcA 1810463 1810789 + PTS system transporter subunit IIA gene gene1750 http://www.ncbi.nlm.nih.gov/gene/?term=spr1836 spr1837 spr1837 adhE adhE 1811697 1814369 - bifunctional acetaldehyde-CoA/alcohol dehydrogenase gene gene1751 http://www.ncbi.nlm.nih.gov/gene/?term=spr1837 spr1838 spr1838 spr1838 1814648 1815058 - hypothetical protein gene gene1752 http://www.ncbi.nlm.nih.gov/gene/?term=spr1838 spr1839 spr1839 spr1839 1815060 1815488 - phosphotyrosine protein phosphatase protein-tyrosine-phosphatase gene gene1753 http://www.ncbi.nlm.nih.gov/gene/?term=spr1839 spr1840 spr1840 yajC yajC 1815535 1815834 - preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene1754 http://www.ncbi.nlm.nih.gov/gene/?term=spr1840 spr1841 spr1841 tktA tktA 1815951 1817927 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene1755 http://www.ncbi.nlm.nih.gov/gene/?term=spr1841 spr1842 spr1842 spr1842 1818041 1819132 - L-ascorbate 6-phosphate lactonase gene gene1756 http://www.ncbi.nlm.nih.gov/gene/?term=spr1842 spr1843 spr1843 spr1843 1819244 1820917 - hypothetical protein transcriptional regulator gene gene1757 http://www.ncbi.nlm.nih.gov/gene/?term=spr1843 spr1844 spr1844 araD araD 1821096 1821800 - L-ribulose-5-phosphate 4-epimerase catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways gene gene1758 http://www.ncbi.nlm.nih.gov/gene/?term=spr1844 spr1845 spr1845 sga sga 1821802 1822665 - L-xylulose 5-phosphate 3-epimerase L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated%3B may be involved in the utilization of 2%2C3-diketo-L-gulonate gene gene1759 http://www.ncbi.nlm.nih.gov/gene/?term=spr1845 spr1846 spr1846 ulaD ulaD 1822669 1823334 - 3-keto-L-gulonate-6-phosphate decarboxylase catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization gene gene1760 http://www.ncbi.nlm.nih.gov/gene/?term=spr1846 spr1847 spr1847 PTS-EII PTS-EII 1823351 1823836 - PTS system transporter subunit IIA gene gene1761 http://www.ncbi.nlm.nih.gov/gene/?term=spr1847 spr1848 spr1848 PTS-EII PTS-EII 1823913 1824194 - PTS system transporter subunit IIB gene gene1762 http://www.ncbi.nlm.nih.gov/gene/?term=spr1848 spr1849 spr1849 ulaA ulaA 1824217 1825674 - PTS system ascorbate-specific transporter subunit IIC membrane component%3B functions with enzymes IIB (sgaB%3B ulaB) and IIA (sgaA%3B ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate%3B sgaTBA are regulated by yifQ as well as Crp and Fnr gene gene1763 http://www.ncbi.nlm.nih.gov/gene/?term=spr1849 spr1850 spr1850 spr1850 1825805 1826428 - hypothetical protein gene gene1764 http://www.ncbi.nlm.nih.gov/gene/?term=spr1850 spr1851 spr1851 spr1851 1826479 1827465 - hypothetical protein gene gene1765 http://www.ncbi.nlm.nih.gov/gene/?term=spr1851 spr1852 spr1852 spr1852 1827484 1828314 - SpoIIIJ family protein Similar to Bacillus subtilis SpoIIIJ gene gene1766 http://www.ncbi.nlm.nih.gov/gene/?term=spr1852 spr1853 spr1853 rnpA rnpA 1828283 1828654 - ribonuclease P protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene1767 http://www.ncbi.nlm.nih.gov/gene/?term=spr1853 spr1854 spr1854 ackA ackA 1828803 1829993 - acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA gene gene1768 http://www.ncbi.nlm.nih.gov/gene/?term=spr1854 spr1855 spr1855 spr1855 1830044 1830997 - hypothetical protein gene gene1769 http://www.ncbi.nlm.nih.gov/gene/?term=spr1855 spr1856 spr1856 spr1856 1831058 1831652 - gene gene1770 http://www.ncbi.nlm.nih.gov/gene/?term=spr1856 spr1858 spr1858 spr1858 1831789 1832202 - hypothetical protein gene gene1771 http://www.ncbi.nlm.nih.gov/gene/?term=spr1858 spr1859 spr1859 spr1859 1832180 1832686 - hypothetical protein Competence induced%3B related to comYD gene gene1772 http://www.ncbi.nlm.nih.gov/gene/?term=spr1859 spr1861 spr1861 cglD cglD 1832869 1833351 - competence protein CglD Competence induced%3B comG-like protein D gene gene1773 http://www.ncbi.nlm.nih.gov/gene/?term=spr1861 spr1862 spr1862 cglC cglC 1833266 1833592 - competence protein CglC Competence induced%3B comG-like protein C gene gene1774 http://www.ncbi.nlm.nih.gov/gene/?term=spr1862 spr1863 spr1863 cglB cglB 1833594 1834685 - competence protein CglB Competence induced%3B comG-like protein B gene gene1775 http://www.ncbi.nlm.nih.gov/gene/?term=spr1863 spr1864 spr1864 cglA cglA 1834558 1835499 - competence protein CglA Competence induced%3B comG-like protein A%3B Also known as cilD gene gene1776 http://www.ncbi.nlm.nih.gov/gene/?term=spr1864 spr1865 spr1865 spr1865 1835575 1835946 - hypothetical protein DNA binding protein gene gene1777 http://www.ncbi.nlm.nih.gov/gene/?term=spr1865 spr1866 spr1866 adh adh 1836091 1837149 - zinc-containing alcohol dehydrogenase gene gene1778 http://www.ncbi.nlm.nih.gov/gene/?term=spr1866 spr1867 spr1867 nagA nagA 1837312 1838463 - N-acetylglucosamine-6-phosphate deacetylase gene gene1779 http://www.ncbi.nlm.nih.gov/gene/?term=spr1867 spr1868 spr1868 spr1868 1838616 1840433 - hypothetical protein gene gene1780 http://www.ncbi.nlm.nih.gov/gene/?term=spr1868 spr1869 spr1869 tgt tgt 1840531 1841673 - queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene1781 http://www.ncbi.nlm.nih.gov/gene/?term=spr1869 spr1870 spr1870 spr1870 1841803 1842660 + hypothetical protein gene gene1782 http://www.ncbi.nlm.nih.gov/gene/?term=spr1870 spr1871 spr1871 pcp-truncation pcp-truncation 1842688 1843214 - gene gene1783 http://www.ncbi.nlm.nih.gov/gene/?term=spr1871 spr1873 spr1873 spr1873 1843412 1843770 - gene gene1784 http://www.ncbi.nlm.nih.gov/gene/?term=spr1873 spr1874 spr1874 marR marR 1843781 1844119 - MarR family transcriptional regulator gene gene1785 http://www.ncbi.nlm.nih.gov/gene/?term=spr1874 spr1875 spr1875 spr1875 1844525 1845667 - hypothetical protein Probable group B streptococcal surface immunogenic protein gene gene1786 http://www.ncbi.nlm.nih.gov/gene/?term=spr1875 spr1876 spr1876 spr1876 1845833 1846453 - hypothetical protein Low similarity to phosphoglycolate phosphatase gene gene1787 http://www.ncbi.nlm.nih.gov/gene/?term=spr1876 spr1877 spr1877 MATE_transporter MATE_transporter 1846457 1847737 - MATE family transporter gene gene1788 http://www.ncbi.nlm.nih.gov/gene/?term=spr1877 spr1878 spr1878 thrC thrC 1847798 1849282 - threonine synthase catalyzes the formation of L-threonine from O-phospho-L-homoserine gene gene1789 http://www.ncbi.nlm.nih.gov/gene/?term=spr1878 spr1879 spr1879 spr1879 1849358 1850635 - hypothetical protein gene gene1790 http://www.ncbi.nlm.nih.gov/gene/?term=spr1879 spr1880 spr1880 spr1880 1857099 1857533 - cytidine/deoxycytidylate deaminase Low similarity to cytidine/deoxycytidylate deaminases gene gene1807 http://www.ncbi.nlm.nih.gov/gene/?term=spr1880 spr1881 spr1881 gltX gltX 1857547 1859007 - glutamyl-tRNA synthetase Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation gene gene1808 http://www.ncbi.nlm.nih.gov/gene/?term=spr1881 spr1882 spr1882 pgi pgi 1859131 1860480 - glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene1809 http://www.ncbi.nlm.nih.gov/gene/?term=spr1882 spr1883 spr1883 spr1883 1860467 1860646 - hypothetical protein gene gene1810 http://www.ncbi.nlm.nih.gov/gene/?term=spr1883 spr1884 spr1884 guaA guaA 1860650 1861387 - glutamine amidotransferase gene gene1811 http://www.ncbi.nlm.nih.gov/gene/?term=spr1884 spr1885 spr1885 ABC-NP ABC-NP 1861478 1863289 - ABC transporter ATP-binding protein/permease gene gene1812 http://www.ncbi.nlm.nih.gov/gene/?term=spr1885 spr1887 spr1887 ABC-NP ABC-NP 1864031 1865725 - ABC transporter ATP-binding protein/permease gene gene1813 http://www.ncbi.nlm.nih.gov/gene/?term=spr1887 spr1888 spr1888 hexA hexA 1865872 1868445 - DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene1814 http://www.ncbi.nlm.nih.gov/gene/?term=spr1888 spr1889 spr1889 argR argR 1868457 1868903 - arginine repressor ArgR gene gene1815 http://www.ncbi.nlm.nih.gov/gene/?term=spr1889 spr1890 spr1890 argS argS 1869051 1870742 + arginyl-tRNA synthetase catalyzes a two-step reaction%2C first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class-I aminoacyl-tRNA synthetase gene gene1816 http://www.ncbi.nlm.nih.gov/gene/?term=spr1890 spr1891 spr1891 IS1381 IS1381 1871057 1871446 - tranposase gene gene1817 http://www.ncbi.nlm.nih.gov/gene/?term=spr1891 spr1892 spr1892 spr1892 1871577 1872086 + hypothetical protein gene gene1818 http://www.ncbi.nlm.nih.gov/gene/?term=spr1892 spr1893 spr1893 phoP_pnpR phoP_pnpR 1872170 1872877 + response regulator gene gene1819 http://www.ncbi.nlm.nih.gov/gene/?term=spr1893 spr1894 spr1894 phoR-pnpS phoR-pnpS 1872878 1874209 + sensor histidine kinase PnpS gene gene1820 http://www.ncbi.nlm.nih.gov/gene/?term=spr1894 spr1895 spr1895 pstS pstS 1874313 1875251 + phosphate ABC transporter substrate+B766-binding protein gene gene1821 http://www.ncbi.nlm.nih.gov/gene/?term=spr1895 spr1896 spr1896 pstC pstC 1875369 1876232 + phosphate ABC transporter permease gene gene1822 http://www.ncbi.nlm.nih.gov/gene/?term=spr1896 spr1897 spr1897 pstA pstA 1876225 1877040 + phosphate ABC transporter permease gene gene1823 http://www.ncbi.nlm.nih.gov/gene/?term=spr1897 spr1898 spr1898 pstB pstB 1877042 1877794 + phosphate transporter ATP-binding protein ATP-binding protein%3B PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation gene gene1824 http://www.ncbi.nlm.nih.gov/gene/?term=spr1898 spr1899 spr1899 phoU phoU 1877809 1878459 + phosphate transporter PhoU gene gene1825 http://www.ncbi.nlm.nih.gov/gene/?term=spr1899 spr1901 spr1901 spr1901 1879066 1879584 - transcriptional regulator Possible transcriptional regulator gene gene1826 http://www.ncbi.nlm.nih.gov/gene/?term=spr1901 spr1902 spr1902 gpsA gpsA 1879718 1880734 + NAD(P)H-dependent glycerol-3-phosphate dehydrogenase catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate gene gene1827 http://www.ncbi.nlm.nih.gov/gene/?term=spr1902 spr1903 spr1903 galU galU 1880756 1881655 + UTP-glucose-1-phosphate uridylyltransferase gene gene1828 http://www.ncbi.nlm.nih.gov/gene/?term=spr1903 spr1904 spr1904 spr1904 1881722 1882402 - hypothetical protein gene gene1829 http://www.ncbi.nlm.nih.gov/gene/?term=spr1904 spr1905 spr1905 spr1905 1882383 1882928 - 5-formyltetrahydrofolate cyclo-ligase Similar to 5-formyltetrahydrofolate cyclo-ligase gene gene1830 http://www.ncbi.nlm.nih.gov/gene/?term=spr1905 spr1906 spr1906 hipO hipO 1882934 1884064 - hypothetical protein gene gene1831 http://www.ncbi.nlm.nih.gov/gene/?term=spr1906 spr1907 spr1907 dapD dapD 1884132 1884830 - 2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-carboxylate N-succinyltransferase gene gene1832 http://www.ncbi.nlm.nih.gov/gene/?term=spr1907 spr1908 spr1908 spr1908 1885060 1886193 - hypothetical protein gene gene1833 http://www.ncbi.nlm.nih.gov/gene/?term=spr1908 spr1909 spr1909 pbp1b pbp1b 1886036 1888501 - penicillin-binding protein 1B gene gene1834 http://www.ncbi.nlm.nih.gov/gene/?term=spr1909 spr1910 spr1910 tyrS tyrS 1888643 1889899 + tyrosyl-tRNA synthetase catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) gene gene1835 http://www.ncbi.nlm.nih.gov/gene/?term=spr1910 spr1911 spr1911 ctpC ctpC 1889977 1892049 - metal/cation transporter P-type ATPase gene gene1836 http://www.ncbi.nlm.nih.gov/gene/?term=spr1911 spr1912 spr1912 spr1912 1892042 1892353 - hypothetical protein gene gene1837 http://www.ncbi.nlm.nih.gov/gene/?term=spr1912 spr1913 spr1913 rrmA rrmA 1892472 1893320 + rRNA (guanine-N1-)-methyltransferase gene gene1838 http://www.ncbi.nlm.nih.gov/gene/?term=spr1913 spr1914 spr1914 spr1914 1893836 1894042 - hypothetical protein gene gene1839 http://www.ncbi.nlm.nih.gov/gene/?term=spr1914 spr1915 spr1915 spr1915 1894119 1894691 + hypothetical protein gene gene1840 http://www.ncbi.nlm.nih.gov/gene/?term=spr1915 spr1916 spr1916 malP malP 1895736 1897994 - maltodextrin phosphorylase gene gene1841 http://www.ncbi.nlm.nih.gov/gene/?term=spr1916 spr1917 spr1917 malM malM 1898020 1899537 - 4-alpha-glucanotransferase amylomaltase%3B acts to release glucose from maltodextrins gene gene1842 http://www.ncbi.nlm.nih.gov/gene/?term=spr1917 spr1918 spr1918 malX malX 1900087 1901358 + maltose/maltodextrin ABC transporter substrate+B616-binding protein gene gene1843 http://www.ncbi.nlm.nih.gov/gene/?term=spr1918 spr1919 spr1919 malC malC 1901454 1902761 + maltodextrin ABC transporter permease gene gene1844 http://www.ncbi.nlm.nih.gov/gene/?term=spr1919 spr1920 spr1920 malD malD 1902742 1903605 + maltodextrin ABC transporter permease gene gene1845 http://www.ncbi.nlm.nih.gov/gene/?term=spr1920 spr1921 spr1921 malA malA 1903858 1904658 + MalA protein gene gene1846 http://www.ncbi.nlm.nih.gov/gene/?term=spr1921 spr1922 spr1922 malR malR 1904668 1905654 + maltose operon transcriptional repressor gene gene1847 http://www.ncbi.nlm.nih.gov/gene/?term=spr1922 spr1923 spr1923 spr1923 1905946 1906887 - hypothetical protein gene gene1848 http://www.ncbi.nlm.nih.gov/gene/?term=spr1923 spr1924 spr1924 aspS aspS 1906865 1908628 - aspartyl-tRNA synthetase catalyzes a two-step reaction%2C first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene1849 http://www.ncbi.nlm.nih.gov/gene/?term=spr1924 spr1925 spr1925 spr1925 1908980 1909210 - hypothetical protein gene gene1850 http://www.ncbi.nlm.nih.gov/gene/?term=spr1925 spr1926 spr1926 spr1926 1909228 1909869 - hypothetical protein gene gene1851 http://www.ncbi.nlm.nih.gov/gene/?term=spr1926 spr1927 spr1927 spr1927 1909881 1910621 - hypothetical protein gene gene1852 http://www.ncbi.nlm.nih.gov/gene/?term=spr1927 spr1928 spr1928 spr1928 1910618 1910818 - hypothetical protein gene gene1853 http://www.ncbi.nlm.nih.gov/gene/?term=spr1928 spr1929 spr1929 spr1929 1910815 1911030 - transcriptional regulator transcriptional repressor protein gene gene1854 http://www.ncbi.nlm.nih.gov/gene/?term=spr1929 spr1930 spr1930 spr1930 1911031 1911495 - hypothetical protein gene gene1855 http://www.ncbi.nlm.nih.gov/gene/?term=spr1930 spr1931 spr1931 hisS hisS 1911671 1912960 - histidyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene1856 http://www.ncbi.nlm.nih.gov/gene/?term=spr1931 spr1932 spr1932 spr1932 1913038 1914285 - hypothetical protein permease gene gene1857 http://www.ncbi.nlm.nih.gov/gene/?term=spr1932 spr1933 spr1933 rgg rgg 1914475 1915326 - positive transcriptional regulator of glucosyltransferase and Spp phenotype gene gene1858 http://www.ncbi.nlm.nih.gov/gene/?term=spr1933 spr1934 spr1934 spr1934 1915450 1915791 + hypothetical protein gene gene1859 http://www.ncbi.nlm.nih.gov/gene/?term=spr1934 spr1935 spr1935 ilvD ilvD 1916000 1917703 - dihydroxy-acid dehydratase catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis gene gene1860 http://www.ncbi.nlm.nih.gov/gene/?term=spr1935 spr1936 spr1936 tktC tktC 1917936 1918868 - transketolase C-terminal subunit gene gene1861 http://www.ncbi.nlm.nih.gov/gene/?term=spr1936 spr1937 spr1937 tktN tktN 1918865 1919722 - transketolase N-terminal section gene gene1862 http://www.ncbi.nlm.nih.gov/gene/?term=spr1937 spr1938 spr1938 ulaA ulaA 1919726 1921072 - PTS system ascorbate-specific transporter subunit IIC membrane component%3B functions with enzymes IIB (sgaB%3B ulaB) and IIA (sgaA%3B ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate%3B sgaTBA are regulated by yifQ as well as Crp and Fnr gene gene1863 http://www.ncbi.nlm.nih.gov/gene/?term=spr1938 spr1939 spr1939 spr1939 1921085 1921369 - PTS system transporter subunit IIB gene gene1864 http://www.ncbi.nlm.nih.gov/gene/?term=spr1939 spr1940 spr1940 spr1940 1921373 1923403 - hypothetical protein Probable transcriptional antiterminator%2C bglG family gene gene1865 http://www.ncbi.nlm.nih.gov/gene/?term=spr1940 spr1941 spr1941 spr1941 1923594 1924601 + hypothetical protein gene gene1866 http://www.ncbi.nlm.nih.gov/gene/?term=spr1941 spr1942 spr1942 spr1942 1924604 1924804 + hypothetical protein gene gene1867 http://www.ncbi.nlm.nih.gov/gene/?term=spr1942 spr1943 spr1943 rpmF rpmF 1924956 1925138 + 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene1868 http://www.ncbi.nlm.nih.gov/gene/?term=spr1943 spr1944 spr1944 rpmG rpmG 1925154 1925303 + 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene1869 http://www.ncbi.nlm.nih.gov/gene/?term=spr1944 spr1945 spr1945 pcpA pcpA 1925783 1927855 - choline binding protein PcpA gene gene1870 http://www.ncbi.nlm.nih.gov/gene/?term=spr1945 spr1946 spr1946 spr1946 1928212 1928781 + hypothetical protein gene gene1871 http://www.ncbi.nlm.nih.gov/gene/?term=spr1946 spr1947 spr1947 IS1381 IS1381 1928807 1929196 + tranposase gene gene1872 http://www.ncbi.nlm.nih.gov/gene/?term=spr1947 spr1948 spr1948 spr1948 1929248 1929720 - gene gene1873 http://www.ncbi.nlm.nih.gov/gene/?term=spr1948 spr1949 spr1949 spr1949 1929900 1931780 - glycosyl hydrolase-like protein gene gene1874 http://www.ncbi.nlm.nih.gov/gene/?term=spr1949 spr1950 spr1950 spr1950 1931774 1932655 - ROK family protein sugar operon regulatory protein gene gene1875 http://www.ncbi.nlm.nih.gov/gene/?term=spr1950 spr1951 spr1951 spr1951 1932727 1935387 - hypothetical protein Probable sugar hydrolase gene gene1876 http://www.ncbi.nlm.nih.gov/gene/?term=spr1951 spr1952 spr1952 spr1952 1935463 1936767 - hypothetical protein gene gene1877 http://www.ncbi.nlm.nih.gov/gene/?term=spr1952 spr1953 spr1953 spr1953 1936914 1938998 + hypothetical protein Similar to a sugar hydrolase in Lactococcus lactis subsp. lactis gene gene1878 http://www.ncbi.nlm.nih.gov/gene/?term=spr1953 spr1954 spr1954 spr1954 1939038 1940789 - hypothetical protein gene gene1879 http://www.ncbi.nlm.nih.gov/gene/?term=spr1954 spr1955 spr1955 arcA-truncation arcA-truncation 1941478 1942711 + gene gene1880 http://www.ncbi.nlm.nih.gov/gene/?term=spr1955 spr1957 spr1957 arcB arcB 1942769 1943785 + ornithine carbamoyltransferase catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway gene gene1881 http://www.ncbi.nlm.nih.gov/gene/?term=spr1957 spr1958 spr1958 arcC arcC 1943950 1944897 + carbamate kinase catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP gene gene1882 http://www.ncbi.nlm.nih.gov/gene/?term=spr1958 spr1959 spr1959 spr1959 1945106 1946617 + hypothetical protein gene gene1883 http://www.ncbi.nlm.nih.gov/gene/?term=spr1959 spr1960 spr1960 spr1960 1946639 1947970 + hypothetical protein Probable Xaa-His dipeptidase gene gene1884 http://www.ncbi.nlm.nih.gov/gene/?term=spr1960 spr1961 spr1961 spr1961 1948375 1948665 - hypothetical protein gene gene1885 http://www.ncbi.nlm.nih.gov/gene/?term=spr1961 spr1962 spr1962 spr1962 1949304 1950203 - hypothetical protein Probable member of SPFH domain/Band 7 family gene gene1886 http://www.ncbi.nlm.nih.gov/gene/?term=spr1962 spr1963 spr1963 adh2 adh2 1950333 1951484 - iron-containing alcohol dehydrogenase gene gene1887 http://www.ncbi.nlm.nih.gov/gene/?term=spr1963 spr1964 spr1964 fucI fucI 1951630 1953396 - L-fucose isomerase catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose gene gene1888 http://www.ncbi.nlm.nih.gov/gene/?term=spr1964 spr1965 spr1965 spr1965 1953453 1956569 - fucolectin-related protein gene gene1889 http://www.ncbi.nlm.nih.gov/gene/?term=spr1965 spr1966 spr1966 spr1966 1956579 1958873 - hypothetical protein gene gene1890 http://www.ncbi.nlm.nih.gov/gene/?term=spr1966 spr1967 spr1967 PTS-EII PTS-EII 1958932 1959732 - PTS system transporter subunit IID gene gene1891 http://www.ncbi.nlm.nih.gov/gene/?term=spr1967 spr1968 spr1968 PTS-EII PTS-EII 1959729 1960502 - PTS system transporter subunit IIC gene gene1892 http://www.ncbi.nlm.nih.gov/gene/?term=spr1968 spr1969 spr1969 PTS-EII PTS-EII 1960527 1960997 - PTS system transporter subunit IIB gene gene1893 http://www.ncbi.nlm.nih.gov/gene/?term=spr1969 spr1970 spr1970 PTS-EII PTS-EII 1960988 1961434 - PTS system transporter subunit IIA gene gene1894 http://www.ncbi.nlm.nih.gov/gene/?term=spr1970 spr1971 spr1971 fucU fucU 1961412 1961852 - fucose pathway protein gene gene1895 http://www.ncbi.nlm.nih.gov/gene/?term=spr1971 spr1972 spr1972 fucA fucA 1961864 1962517 - L-fuculose phosphate aldolase catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate gene gene1896 http://www.ncbi.nlm.nih.gov/gene/?term=spr1972 spr1973 spr1973 fcsK fcsK 1962617 1964065 - fucose kinase gene gene1897 http://www.ncbi.nlm.nih.gov/gene/?term=spr1973 spr1974 spr1974 fcsR fcsR 1964196 1964969 + fucose operon repressor gene gene1898 http://www.ncbi.nlm.nih.gov/gene/?term=spr1974 spr1975 spr1975 adcA adcA 1966098 1967603 - zinc ABC transporter substrate-binding protein gene gene1899 http://www.ncbi.nlm.nih.gov/gene/?term=spr1975 spr1976 spr1976 adcB adcB 1967613 1968449 - zinc ABC transporter permease gene gene1900 http://www.ncbi.nlm.nih.gov/gene/?term=spr1976 spr1977 spr1977 adcC adcC 1968412 1969116 - ABC transporter ATPase gene gene1901 http://www.ncbi.nlm.nih.gov/gene/?term=spr1977 spr1978 spr1978 adcR adcR 1969116 1969616 - adc operon repressor AdcR gene gene1902 http://www.ncbi.nlm.nih.gov/gene/?term=spr1978 spr1979 spr1979 dltD dltD 1969711 1970994 - poly D-alanine transfer protein gene gene1903 http://www.ncbi.nlm.nih.gov/gene/?term=spr1979 spr1980 spr1980 dltC dltC 1970972 1971211 - D-alanine--poly(phosphoribitol) ligase subunit 2 D-alanyl carrier protein subunit%3B involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid%3B D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid gene gene1904 http://www.ncbi.nlm.nih.gov/gene/?term=spr1980 spr1981 spr1981 dltB dltB 1971225 1972469 - activated D-alanine transport protein gene gene1905 http://www.ncbi.nlm.nih.gov/gene/?term=spr1981 spr1982 spr1982 dltA dltA 1972466 1973932 - D-alanine--poly(phosphoribitol) ligase subunit 1 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid gene gene1906 http://www.ncbi.nlm.nih.gov/gene/?term=spr1982 spr1983 spr1983 spr1983 1974482 1975660 - hypothetical protein gene gene1907 http://www.ncbi.nlm.nih.gov/gene/?term=spr1983 spr1984 spr1984 transposase_H transposase_H 1976116 1977393 - gene gene1908 http://www.ncbi.nlm.nih.gov/gene/?term=spr1984 spr1986 spr1986 spr1986 1978504 1979091 + hypothetical protein gene gene1909 http://www.ncbi.nlm.nih.gov/gene/?term=spr1986 spr1987 spr1987 spr1987 1979178 1979381 - hypothetical protein gene gene1910 http://www.ncbi.nlm.nih.gov/gene/?term=spr1987 spr1988 spr1988 glpF glpF 1979572 1980276 - glycerol uptake facilitator protein gene gene1911 http://www.ncbi.nlm.nih.gov/gene/?term=spr1988 spr1989 spr1989 glpD-truncation glpD-truncation 1980346 1982174 - gene gene1912 http://www.ncbi.nlm.nih.gov/gene/?term=spr1989 spr1991 spr1991 glpK glpK 1982216 1983724 - glycerol kinase Converts glycerol and ADP to glycerol-3-phosphate and ADP gene gene1913 http://www.ncbi.nlm.nih.gov/gene/?term=spr1991 spr1992 spr1992 spr1992 1983883 1985310 - hypothetical protein gene gene1914 http://www.ncbi.nlm.nih.gov/gene/?term=spr1992 spr1993 spr1993 hslO hslO 1985475 1986347 + Hsp33-like chaperonin becomes active under oxidative stress%3B four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive%3B oxidative stress results in oxidized cysteines%2C release of zinc%2C and binding of Hsp33 to aggregation-prone proteins%3B forms dimers and higher order oligomers gene gene1915 http://www.ncbi.nlm.nih.gov/gene/?term=spr1993 spr1994 spr1994 spr1994 1986304 1987314 + hypothetical protein Falls into the same paralogous family as dihydroorotate dehydrogenase gene gene1916 http://www.ncbi.nlm.nih.gov/gene/?term=spr1994 spr1995 spr1995 pspC pspC 1987544 1989649 - choline binding protein A gene gene1917 http://www.ncbi.nlm.nih.gov/gene/?term=spr1995 spr1996 spr1996 spr1996 1989728 1990255 - hypothetical protein gene gene1918 http://www.ncbi.nlm.nih.gov/gene/?term=spr1996 spr1997 spr1997 hk06 hk06 1990338 1991669 - histidine kinase gene gene1919 http://www.ncbi.nlm.nih.gov/gene/?term=spr1997 spr1998 spr1998 rr06 rr06 1991666 1992319 - response regulator gene gene1920 http://www.ncbi.nlm.nih.gov/gene/?term=spr1998 spr1999 spr1999 clpC-truncation clpC-truncation 1993212 1995393 - gene gene1921 http://www.ncbi.nlm.nih.gov/gene/?term=spr1999 spr2001 spr2001 ctsR ctsR 1995395 1995916 - transcriptional regulator CtsR gene gene1922 http://www.ncbi.nlm.nih.gov/gene/?term=spr2001 spr2002 spr2002 ABC-NBD ABC-NBD 1995972 1996700 - ABC transporter ATP-binding protein gene gene1923 http://www.ncbi.nlm.nih.gov/gene/?term=spr2002 spr2003 spr2003 spr2003 1996700 1997707 - ABC transporter substrate-binding protein gene gene1924 http://www.ncbi.nlm.nih.gov/gene/?term=spr2003 spr2004 spr2004 ABC-MSP ABC-MSP 1997745 1998506 - ABC transporter permease gene gene1925 http://www.ncbi.nlm.nih.gov/gene/?term=spr2004 spr2005 spr2005 spr2005 1998466 1998756 - hypothetical protein gene gene1926 http://www.ncbi.nlm.nih.gov/gene/?term=spr2005 spr2006 spr2006 cbpD cbpD 1999012 2000358 - choline binding protein D gene gene1927 http://www.ncbi.nlm.nih.gov/gene/?term=spr2006 spr2007 spr2007 spr2007 2000447 2000713 - hypothetical protein gene gene1928 http://www.ncbi.nlm.nih.gov/gene/?term=spr2007 spr2008 spr2008 dnaC dnaC 2000715 2002067 - replicative DNA helicase unwinds double stranded DNA gene gene1929 http://www.ncbi.nlm.nih.gov/gene/?term=spr2008 spr2009 spr2009 rplI rplI 2002111 2002563 - 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene1930 http://www.ncbi.nlm.nih.gov/gene/?term=spr2009 spr2010 spr2010 spr2010 2002560 2004533 - DHH subfamily 1 protein Probable member of DHH superfamily gene gene1931 http://www.ncbi.nlm.nih.gov/gene/?term=spr2010 spr2011 spr2011 spr2011 2004669 2005217 - ribosomal subunit interface protein Probable member of ribosomal protein S30AE family gene gene1932 http://www.ncbi.nlm.nih.gov/gene/?term=spr2011 spr2012 spr2012 comFC comFC 2005297 2005959 - competence protein ComF gene gene1933 http://www.ncbi.nlm.nih.gov/gene/?term=spr2012 spr2013 spr2013 comFA comFA 2005956 2007254 - helicase gene gene1934 http://www.ncbi.nlm.nih.gov/gene/?term=spr2013 spr2014 spr2014 spr2014 2007310 2007945 + hypothetical protein gene gene1935 http://www.ncbi.nlm.nih.gov/gene/?term=spr2014 spr2015 spr2015 cycK cycK 2008230 2009150 + cysteine synthase gene gene1936 http://www.ncbi.nlm.nih.gov/gene/?term=spr2015 spr2016 spr2016 transposase_G transposase_G 2009347 2009616 - hypothetical protein gene gene1937 http://www.ncbi.nlm.nih.gov/gene/?term=spr2016 spr2019 spr2019 tsf tsf 2010734 2011774 - elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene1938 http://www.ncbi.nlm.nih.gov/gene/?term=spr2019 spr2020 spr2020 rpsB rpsB 2011840 2012619 - 30S ribosomal protein S2 one of the last subunits in the assembly of the 30S subunit%3B absence of S2 does not inhibit assembly but results in an inactive subunit gene gene1939 http://www.ncbi.nlm.nih.gov/gene/?term=spr2020 spr2021 spr2021 gsp-781 gsp-781 2012843 2014021 - general stress protein GSP-781 gene gene1940 http://www.ncbi.nlm.nih.gov/gene/?term=spr2021 spr2022 spr2022 mreD mreD 2014115 2014609 - rod shpae-determining protein MreD gene gene1941 http://www.ncbi.nlm.nih.gov/gene/?term=spr2022 spr2023 spr2023 mreC mreC 2014609 2015427 - rod shape-determining protein MreC in some organisms this protein is a transmembrane protein while in others it is periplasmic%3B involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall gene gene1942 http://www.ncbi.nlm.nih.gov/gene/?term=spr2023 spr2024 spr2024 ABC-MSP ABC-MSP 2015486 2016280 - ABC transporter permease gene gene1943 http://www.ncbi.nlm.nih.gov/gene/?term=spr2024 spr2025 spr2025 cbiO cbiO 2016273 2017112 - cobalt transporter ATP-binding subunit with CbiNQ forms the ABC transporter for cobalt import%3B Streptococcus has two adjacent copies of this gene gene gene1944 http://www.ncbi.nlm.nih.gov/gene/?term=spr2025 spr2026 spr2026 cbiO cbiO 2017097 2017924 - cobalt transporter ATP-binding subunit with CbiNQ forms the ABC transporter for cobalt import%3B Streptococcus has two adjacent copies of this gene gene gene1945 http://www.ncbi.nlm.nih.gov/gene/?term=spr2026 spr2027 spr2027 pgsA pgsA 2017921 2018466 - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene1946 http://www.ncbi.nlm.nih.gov/gene/?term=spr2027 spr2028 spr2028 spr2028 2018477 2019307 - hypothetical protein gene gene1947 http://www.ncbi.nlm.nih.gov/gene/?term=spr2028 spr2029 spr2029 spr2029 2019340 2020623 - hypothetical protein Probable protease/peptidase gene gene1948 http://www.ncbi.nlm.nih.gov/gene/?term=spr2029 spr2030 spr2030 spr2030 2020620 2021870 - hypothetical protein gene gene1949 http://www.ncbi.nlm.nih.gov/gene/?term=spr2030 spr2031 spr2031 spr2031 2022029 2022397 + hypothetical protein gene gene1950 http://www.ncbi.nlm.nih.gov/gene/?term=spr2031 spr2032 spr2032 recF recF 2022400 2023497 + recombination protein F Required for DNA replication%3B binds preferentially to single-stranded%2C linear DNA gene gene1951 http://www.ncbi.nlm.nih.gov/gene/?term=spr2032 spr2033 spr2033 imdH imdH 2023548 2025026 - inosine 5'-monophosphate dehydrogenase catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate gene gene1952 http://www.ncbi.nlm.nih.gov/gene/?term=spr2033 spr2034 spr2034 trpS trpS 2025178 2026203 - tryptophanyl-tRNA synthetase II catalyzes a two-step reaction%2C first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA gene gene1953 http://www.ncbi.nlm.nih.gov/gene/?term=spr2034 spr2035 spr2035 ABC-NBD ABC-NBD 2026409 2028031 + ABC transporter ATP-binding protein gene gene1954 http://www.ncbi.nlm.nih.gov/gene/?term=spr2035 spr2036 spr2036 spr2036 2028093 2030645 + ABC transporter permease gene gene1955 http://www.ncbi.nlm.nih.gov/gene/?term=spr2036 spr2037 spr2037 spr2037 2030746 2032278 - gene gene1956 http://www.ncbi.nlm.nih.gov/gene/?term=spr2037 spr2040 spr2040 spr2040 2032457 2032999 + hypothetical protein Probable transcriptional regulator of TetR family gene gene1957 http://www.ncbi.nlm.nih.gov/gene/?term=spr2040 spr2041 spr2041 comE comE 2033242 2033994 - response regulator Required for induction of competence gene gene1960 http://www.ncbi.nlm.nih.gov/gene/?term=spr2041 spr2042 spr2042 comD comD 2033991 2035316 - sensor histidine kinase ComD Required for induction of competence gene gene1961 http://www.ncbi.nlm.nih.gov/gene/?term=spr2042 spr2043 spr2043 comC comC 2035337 2035462 - competence stimulating peptide gene gene1962 http://www.ncbi.nlm.nih.gov/gene/?term=spr2043 spr2044 spr2044 spr2044 2035744 2036223 - rRNA large subunit methyltransferase SPOUT methyltransferase%3B crystal structure shows homodimer%3B in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA gene gene1964 http://www.ncbi.nlm.nih.gov/gene/?term=spr2044 spr2045 spr2045 sphtra sphtra 2036394 2037587 + serine protease gene gene1965 http://www.ncbi.nlm.nih.gov/gene/?term=spr2045 spr2046 spr2046 spo0J spo0J 2037645 2038403 + chromosome segregation protein gene gene1966 http://www.ncbi.nlm.nih.gov/gene/?term=spr2046 sprr01 sprr01 rRNA_16S-1 rRNA_16S-1 15161 16674 + 16S ribosomal RNA rRNA gene14 http://www.ncbi.nlm.nih.gov/gene/?term=sprr01 sprr02 sprr02 rRNA_23S-1 rRNA_23S-1 16945 19846 + 23S ribosomal RNA rRNA gene16 http://www.ncbi.nlm.nih.gov/gene/?term=sprr02 sprr03 sprr03 rRNA_5S-1 rRNA_5S-1 19924 20038 + 5S ribosomal RNA rRNA gene17 http://www.ncbi.nlm.nih.gov/gene/?term=sprr03 sprr04 sprr04 rRNA_5S-2 rRNA_5S-2 1692291 1692405 - 5S ribosomal RNA rRNA gene1617 http://www.ncbi.nlm.nih.gov/gene/?term=sprr04 sprr05 sprr05 rRNA_23S-2 rRNA_23S-2 1692483 1695384 - 23S ribosomal RNA rRNA gene1618 http://www.ncbi.nlm.nih.gov/gene/?term=sprr05 sprr06 sprr06 rRNA_16S-2 rRNA_16S-2 1695655 1697168 - 16S ribosomal RNA rRNA gene1620 http://www.ncbi.nlm.nih.gov/gene/?term=sprr06 sprr07 sprr07 rRNA_5S-3 rRNA_5S-3 1789841 1789955 - 5S ribosomal RNA rRNA gene1729 http://www.ncbi.nlm.nih.gov/gene/?term=sprr07 sprr08 sprr08 rRNA_23S-3 rRNA_23S-3 1790033 1792934 - 23S ribosomal RNA rRNA gene1730 http://www.ncbi.nlm.nih.gov/gene/?term=sprr08 sprr09 sprr09 rRNA_16S-3 rRNA_16S-3 1793205 1794718 - 16S ribosomal RNA rRNA gene1732 http://www.ncbi.nlm.nih.gov/gene/?term=sprr09 sprr10 sprr10 rRNA_5S-4 rRNA_5S-4 1851766 1851880 - 5S ribosomal RNA rRNA gene1802 http://www.ncbi.nlm.nih.gov/gene/?term=sprr10 sprr11 sprr11 rRNA_23S-4 rRNA_23S-4 1851958 1854859 - 23S ribosomal RNA rRNA gene1803 http://www.ncbi.nlm.nih.gov/gene/?term=sprr11 sprr12 sprr12 rRNA_16S-4 rRNA_16S-4 1855130 1856643 - 16S ribosomal RNA rRNA gene1805 http://www.ncbi.nlm.nih.gov/gene/?term=sprr12 sprs01 sprs01 scRNA scRNA 24631 24815 + ncRNA gene26 http://www.ncbi.nlm.nih.gov/gene/?term=sprs01 sprs02 sprs02 rnpB rnpB 336620 337023 + gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=sprs02 sprs03 sprs03 ssrA ssrA 773607 773951 + tmRNA gene733 http://www.ncbi.nlm.nih.gov/gene/?term=sprs03 sprt01 sprt01 tRNA-Glu1 tRNA-Glu1 14827 14898 + tRNA-Glu tRNA gene13 http://www.ncbi.nlm.nih.gov/gene/?term=sprt01 sprt02 sprt02 tRNA-Ala1 tRNA-Ala1 16748 16820 + tRNA-Ala tRNA gene15 http://www.ncbi.nlm.nih.gov/gene/?term=sprt02 sprt03 sprt03 tRNA-Asn1 tRNA-Asn1 20044 20117 + tRNA-Asn tRNA gene18 http://www.ncbi.nlm.nih.gov/gene/?term=sprt03 sprt04 sprt04 tRNA-Tyr1 tRNA-Tyr1 759414 759494 + tRNA-Tyr tRNA gene718 http://www.ncbi.nlm.nih.gov/gene/?term=sprt04 sprt05 sprt05 tRNA-Gln1 tRNA-Gln1 759504 759575 + tRNA-Gln tRNA gene719 http://www.ncbi.nlm.nih.gov/gene/?term=sprt05 sprt06 sprt06 tRNA-Ser1 tRNA-Ser1 774137 774224 - tRNA-Ser tRNA gene734 http://www.ncbi.nlm.nih.gov/gene/?term=sprt06 sprt07 sprt07 tRNA-Thr1 tRNA-Thr1 904864 904936 + tRNA-Thr tRNA gene859 http://www.ncbi.nlm.nih.gov/gene/?term=sprt07 sprt08 sprt08 tRNA-Arg1 tRNA-Arg1 1131546 1131617 - tRNA-Arg tRNA gene1056 http://www.ncbi.nlm.nih.gov/gene/?term=sprt08 sprt09 sprt09 tRNA-Arg2 tRNA-Arg2 1173377 1173448 - tRNA-Arg tRNA gene1096 http://www.ncbi.nlm.nih.gov/gene/?term=sprt09 sprt10 sprt10 tRNA-Leu1 tRNA-Leu1 1421994 1422079 - tRNA-Leu tRNA gene1338 http://www.ncbi.nlm.nih.gov/gene/?term=sprt10 sprt11 sprt11 tRNA-Lys1 tRNA-Lys1 1590539 1590611 + tRNA-Lys tRNA gene1507 http://www.ncbi.nlm.nih.gov/gene/?term=sprt11 sprt12 sprt12 tRNA-Ser2 tRNA-Ser2 1690783 1690870 - tRNA-Ser tRNA gene1600 http://www.ncbi.nlm.nih.gov/gene/?term=sprt12 sprt13 sprt13 tRNA-Ile1 tRNA-Ile1 1690877 1690950 - tRNA-Ile tRNA gene1601 http://www.ncbi.nlm.nih.gov/gene/?term=sprt13 sprt14 sprt14 tRNA-Gly1 tRNA-Gly1 1690986 1691056 - tRNA-Gly tRNA gene1602 http://www.ncbi.nlm.nih.gov/gene/?term=sprt14 sprt15 sprt15 tRNA-Phe1 tRNA-Phe1 1691076 1691148 - tRNA-Phe tRNA gene1603 http://www.ncbi.nlm.nih.gov/gene/?term=sprt15 sprt16 sprt16 tRNA-Met1 tRNA-Met1 1691152 1691225 - tRNA-Met tRNA gene1604 http://www.ncbi.nlm.nih.gov/gene/?term=sprt16 sprt17 sprt17 tRNA-Ser3 tRNA-Ser3 1691239 1691328 - tRNA-Ser tRNA gene1605 http://www.ncbi.nlm.nih.gov/gene/?term=sprt17 sprt18 sprt18 tRNA-Met2 tRNA-Met2 1691339 1691412 - tRNA-Met tRNA gene1606 http://www.ncbi.nlm.nih.gov/gene/?term=sprt18 sprt19 sprt19 tRNA-Met3 tRNA-Met3 1691426 1691499 - tRNA-Met tRNA gene1607 http://www.ncbi.nlm.nih.gov/gene/?term=sprt19 sprt20 sprt20 tRNA-Pro1 tRNA-Pro1 1691505 1691578 - tRNA-Pro tRNA gene1608 http://www.ncbi.nlm.nih.gov/gene/?term=sprt20 sprt21 sprt21 tRNA-Arg3 tRNA-Arg3 1691594 1691667 - tRNA-Arg tRNA gene1609 http://www.ncbi.nlm.nih.gov/gene/?term=sprt21 sprt22 sprt22 tRNA-Leu2 tRNA-Leu2 1691677 1691762 - tRNA-Leu tRNA gene1610 http://www.ncbi.nlm.nih.gov/gene/?term=sprt22 sprt23 sprt23 tRNA-Gly2 tRNA-Gly2 1691770 1691841 - tRNA-Gly tRNA gene1611 http://www.ncbi.nlm.nih.gov/gene/?term=sprt23 sprt24 sprt24 tRNA-Thr2 tRNA-Thr2 1691864 1691936 - tRNA-Thr tRNA gene1612 http://www.ncbi.nlm.nih.gov/gene/?term=sprt24 sprt25 sprt25 tRNA-Leu3 tRNA-Leu3 1691955 1692036 - tRNA-Leu tRNA gene1613 http://www.ncbi.nlm.nih.gov/gene/?term=sprt25 sprt26 sprt26 tRNA-Lys2 tRNA-Lys2 1692042 1692114 - tRNA-Lys tRNA gene1614 http://www.ncbi.nlm.nih.gov/gene/?term=sprt26 sprt27 sprt27 tRNA-Asp1 tRNA-Asp1 1692139 1692211 - tRNA-Asp tRNA gene1615 http://www.ncbi.nlm.nih.gov/gene/?term=sprt27 sprt28 sprt28 tRNA-Val1 tRNA-Val1 1692214 1692286 - tRNA-Val tRNA gene1616 http://www.ncbi.nlm.nih.gov/gene/?term=sprt28 sprt29 sprt29 tRNA-Ala2 tRNA-Ala2 1695509 1695581 - tRNA-Ala tRNA gene1619 http://www.ncbi.nlm.nih.gov/gene/?term=sprt29 sprt30 sprt30 tRNA-Glu2 tRNA-Glu2 1697431 1697502 - tRNA-Glu tRNA gene1621 http://www.ncbi.nlm.nih.gov/gene/?term=sprt30 sprt31 sprt31 tRNA-Cys tRNA-Cys 1752048 1752118 + tRNA-Cys tRNA gene1677 http://www.ncbi.nlm.nih.gov/gene/?term=sprt31 sprt32 sprt32 tRNA-Pro2 tRNA-Pro2 1789055 1789128 - tRNA-Pro tRNA gene1720 http://www.ncbi.nlm.nih.gov/gene/?term=sprt32 sprt33 sprt33 tRNA-Arg4 tRNA-Arg4 1789144 1789217 - tRNA-Arg tRNA gene1721 http://www.ncbi.nlm.nih.gov/gene/?term=sprt33 sprt34 sprt34 tRNA-Leu4 tRNA-Leu4 1789227 1789312 - tRNA-Leu tRNA gene1722 http://www.ncbi.nlm.nih.gov/gene/?term=sprt34 sprt35 sprt35 tRNA-Gly3 tRNA-Gly3 1789320 1789391 - tRNA-Gly tRNA gene1723 http://www.ncbi.nlm.nih.gov/gene/?term=sprt35 sprt36 sprt36 tRNA-Thr3 tRNA-Thr3 1789414 1789486 - tRNA-Thr tRNA gene1724 http://www.ncbi.nlm.nih.gov/gene/?term=sprt36 sprt37 sprt37 tRNA-Leu5 tRNA-Leu5 1789505 1789586 - tRNA-Leu tRNA gene1725 http://www.ncbi.nlm.nih.gov/gene/?term=sprt37 sprt38 sprt38 tRNA-Lys3 tRNA-Lys3 1789592 1789664 - tRNA-Lys tRNA gene1726 http://www.ncbi.nlm.nih.gov/gene/?term=sprt38 sprt39 sprt39 tRNA-Asp2 tRNA-Asp2 1789689 1789761 - tRNA-Asp tRNA gene1727 http://www.ncbi.nlm.nih.gov/gene/?term=sprt39 sprt40 sprt40 tRNA-Val2 tRNA-Val2 1789764 1789836 - tRNA-Val tRNA gene1728 http://www.ncbi.nlm.nih.gov/gene/?term=sprt40 sprt41 sprt41 tRNA-Ala3 tRNA-Ala3 1793059 1793131 - tRNA-Ala tRNA gene1731 http://www.ncbi.nlm.nih.gov/gene/?term=sprt41 sprt42 sprt42 tRNA-Glu3 tRNA-Glu3 1794981 1795052 - tRNA-Glu tRNA gene1733 http://www.ncbi.nlm.nih.gov/gene/?term=sprt42 sprt43 sprt43 tRNA-Leu6 tRNA-Leu6 1850742 1850825 - tRNA-Leu tRNA gene1791 http://www.ncbi.nlm.nih.gov/gene/?term=sprt43 sprt44 sprt44 tRNA-Gln2 tRNA-Gln2 1850835 1850906 - tRNA-Gln tRNA gene1792 http://www.ncbi.nlm.nih.gov/gene/?term=sprt44 sprt45 sprt45 tRNA-His tRNA-His 1850917 1850989 - tRNA-His tRNA gene1793 http://www.ncbi.nlm.nih.gov/gene/?term=sprt45 sprt46 sprt46 tRNA-Trp tRNA-Trp 1851004 1851074 - tRNA-Trp tRNA gene1794 http://www.ncbi.nlm.nih.gov/gene/?term=sprt46 sprt47 sprt47 tRNA-Tyr2 tRNA-Tyr2 1851079 1851159 - tRNA-Tyr tRNA gene1795 http://www.ncbi.nlm.nih.gov/gene/?term=sprt47 sprt48 sprt48 tRNA-Phe2 tRNA-Phe2 1851172 1851244 - tRNA-Phe tRNA gene1796 http://www.ncbi.nlm.nih.gov/gene/?term=sprt48 sprt49 sprt49 tRNA-Met4 tRNA-Met4 1851248 1851321 - tRNA-Met tRNA gene1797 http://www.ncbi.nlm.nih.gov/gene/?term=sprt49 sprt50 sprt50 tRNA-Ser4 tRNA-Ser4 1851332 1851421 - tRNA-Ser tRNA gene1798 http://www.ncbi.nlm.nih.gov/gene/?term=sprt50 sprt51 sprt51 tRNA-Ile2 tRNA-Ile2 1851505 1851578 - tRNA-Ile tRNA gene1799 http://www.ncbi.nlm.nih.gov/gene/?term=sprt51 sprt52 sprt52 tRNA-Gly4 tRNA-Gly4 1851613 1851683 - tRNA-Gly tRNA gene1800 http://www.ncbi.nlm.nih.gov/gene/?term=sprt52 sprt53 sprt53 tRNA-Val3 tRNA-Val3 1851689 1851761 - tRNA-Val tRNA gene1801 http://www.ncbi.nlm.nih.gov/gene/?term=sprt53 sprt54 sprt54 tRNA-Ala4 tRNA-Ala4 1854984 1855056 - tRNA-Ala tRNA gene1804 http://www.ncbi.nlm.nih.gov/gene/?term=sprt54 sprt55 sprt55 tRNA-Glu4 tRNA-Glu4 1856906 1856977 - tRNA-Glu tRNA gene1806 http://www.ncbi.nlm.nih.gov/gene/?term=sprt55 sprt56 sprt56 tRNA-Asn2 tRNA-Asn2 2033040 2033113 - tRNA-Asn tRNA gene1958 http://www.ncbi.nlm.nih.gov/gene/?term=sprt56 sprt57 sprt57 tRNA-Glu5 tRNA-Glu5 2033119 2033190 - tRNA-Glu tRNA gene1959 http://www.ncbi.nlm.nih.gov/gene/?term=sprt57 sprt58 sprt58 tRNA-Arg5 tRNA-Arg5 2035627 2035700 - tRNA-Arg tRNA gene1963 http://www.ncbi.nlm.nih.gov/gene/?term=sprt58