locus-tag	class	description
ES300_RS00010	COG0592	DNA-directed DNA polymerase activity
ES300_RS00020	COG0012	GTP binding
ES300_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ES300_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ES300_RS00055	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ES300_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ES300_RS00130	COG0756	dUTP diphosphatase activity
ES300_RS00140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ES300_RS00155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ES300_RS00170	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ES300_RS00170	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ES300_RS00175	COG1832	CoA-binding protein
ES300_RS00180	COG2855	membrane
ES300_RS00185	COG0436	Aminotransferase
ES300_RS00200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES300_RS00215	COG2274	protein secretion by the type I secretion system
ES300_RS00220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ES300_RS00230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ES300_RS00235	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ES300_RS00245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ES300_RS00260	COG0151	Belongs to the GarS family
ES300_RS00265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ES300_RS00280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ES300_RS00285	COG3583	domain protein
ES300_RS00285	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ES300_RS00285	COG3064	Membrane
ES300_RS00300	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS00305	COG3715	PTS system
ES300_RS00310	COG3716	PTS system mannose fructose sorbose family IID component
ES300_RS00320	COG2222	sugar isomerase
ES300_RS00330	COG2514	catechol 2,3-dioxygenase activity
ES300_RS00335	COG1937	Protein conserved in bacteria
ES300_RS00360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ES300_RS00365	COG0569	domain protein
ES300_RS00375	COG1215	transferase activity, transferring glycosyl groups
ES300_RS00395	COG5002	protein histidine kinase activity
ES300_RS00415	COG4209	transmembrane transport
ES300_RS00420	COG0395	ABC-type sugar transport system, permease component
ES300_RS00425	COG1653	transport
ES300_RS00455	COG1695	Transcriptional regulator
ES300_RS00480	COG0546	phosphoglycolate phosphatase activity
ES300_RS00485	COG1760	l-serine dehydratase
ES300_RS00490	COG1760	l-serine dehydratase
ES300_RS00520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS00610	COG0482	sulfurtransferase activity
ES300_RS00615	COG0494	nUDIX hydrolase
ES300_RS00620	COG0445	tRNA wobble uridine modification
ES300_RS00650	COG1214	PFAM Peptidase M22, glycoprotease
ES300_RS00685	COG0438	transferase activity, transferring glycosyl groups
ES300_RS00715	COG1396	sequence-specific DNA binding
ES300_RS00750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS00760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS00765	COG1464	Belongs to the NlpA lipoprotein family
ES300_RS00770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES300_RS00775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ES300_RS00795	COG2972	Histidine kinase
ES300_RS00800	COG4753	response regulator
ES300_RS00800	COG2207	Transcriptional regulator
ES300_RS00810	COG1780	Probably involved in ribonucleotide reductase function
ES300_RS00840	COG0019	diaminopimelate decarboxylase activity
ES300_RS00895	COG2818	Glycosylase
ES300_RS00920	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ES300_RS00925	COG0006	proline dipeptidase activity
ES300_RS00930	COG1393	Belongs to the ArsC family
ES300_RS00955	COG0285	dihydrofolate synthase activity
ES300_RS00965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ES300_RS01035	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ES300_RS01060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ES300_RS01100	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ES300_RS01115	COG0201	protein transport
ES300_RS01125	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ES300_RS01130	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ES300_RS01140	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ES300_RS01145	COG0202	RNA polymerase activity
ES300_RS01155	COG3830	Belongs to the UPF0237 family
ES300_RS01175	COG3842	ATPase activity
ES300_RS01190	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ES300_RS01195	COG1349	DNA-binding transcription factor activity
ES300_RS01205	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES300_RS01210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS01215	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS01220	COG1882	Formate acetyltransferase
ES300_RS01240	COG0495	leucyl-tRNA aminoacylation
ES300_RS01270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ES300_RS01275	COG4589	Belongs to the CDS family
ES300_RS01280	COG0750	zinc metalloprotease
ES300_RS01290	COG2723	6-phospho-beta-galactosidase activity
ES300_RS01295	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ES300_RS01310	COG1523	belongs to the glycosyl hydrolase 13 family
ES300_RS01330	COG2176	DNA-directed DNA polymerase activity
ES300_RS01350	COG2309	aminopeptidase activity
ES300_RS01355	COG2261	transglycosylase associated protein
ES300_RS01360	COG1187	pseudouridine synthase activity
ES300_RS01365	COG3579	cysteine-type endopeptidase activity
ES300_RS01370	COG3716	PTS system mannose fructose sorbose family IID component
ES300_RS01375	COG3715	PTS system
ES300_RS01385	COG1064	alcohol dehydrogenase
ES300_RS01390	COG0561	phosphatase activity
ES300_RS01395	COG2252	PERMEase
ES300_RS01405	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ES300_RS01410	COG0285	dihydrofolate synthase activity
ES300_RS01420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ES300_RS01420	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ES300_RS01430	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ES300_RS01450	COG2723	6-phospho-beta-galactosidase activity
ES300_RS01465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS01465	COG3711	transcriptional antiterminator
ES300_RS01480	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS01495	COG0386	Belongs to the glutathione peroxidase family
ES300_RS01500	COG5492	domain, Protein
ES300_RS01530	COG1028	Short-chain dehydrogenase reductase Sdr
ES300_RS01540	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ES300_RS01545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS01550	COG3715	PTS system
ES300_RS01555	COG3716	PTS system mannose fructose sorbose family IID component
ES300_RS01570	COG1609	Transcriptional regulator
ES300_RS01595	COG4839	cell division protein FtsL
ES300_RS01600	COG0768	penicillin binding
ES300_RS01605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ES300_RS01625	COG0366	Alpha amylase catalytic
ES300_RS01630	COG4166	transmembrane transport
ES300_RS01645	COG4464	protein tyrosine phosphatase activity
ES300_RS01650	COG3944	biosynthesis protein
ES300_RS01655	COG0489	protein tyrosine kinase activity
ES300_RS01685	COG0438	transferase activity, transferring glycosyl groups
ES300_RS01710	COG0562	UDP-galactopyranose mutase
ES300_RS01715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ES300_RS01725	COG1088	dTDP-glucose 4,6-dehydratase activity
ES300_RS01730	COG1091	dTDP-4-dehydrorhamnose reductase activity
ES300_RS01745	COG4166	transmembrane transport
ES300_RS01750	COG0366	Alpha amylase catalytic
ES300_RS01755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES300_RS01780	COG0116	Belongs to the methyltransferase superfamily
ES300_RS01790	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ES300_RS01795	COG0745	RESPONSE REGULATOR receiver
ES300_RS01830	COG4585	Histidine kinase
ES300_RS01835	COG2197	response regulator
ES300_RS01865	COG2213	PTS system mannitol-specific
ES300_RS01870	COG3711	transcriptional antiterminator
ES300_RS01875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS01890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ES300_RS01900	COG0681	Belongs to the peptidase S26 family
ES300_RS01925	COG1115	amino acid carrier protein
ES300_RS01950	COG0527	aspartate kinase activity
ES300_RS01955	COG1024	Enoyl-CoA hydratase
ES300_RS01960	COG1846	Transcriptional regulator
ES300_RS01970	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ES300_RS01980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ES300_RS01985	COG1028	Short-chain dehydrogenase reductase Sdr
ES300_RS01990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ES300_RS02005	COG0439	Biotin carboxylase
ES300_RS02010	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ES300_RS02050	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ES300_RS02065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ES300_RS02070	COG1442	glycosyl transferase family 8
ES300_RS02075	COG1442	glycosyl transferase family 8
ES300_RS02080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ES300_RS02090	COG1461	Dihydroxyacetone kinase
ES300_RS02095	COG0028	Belongs to the TPP enzyme family
ES300_RS02100	COG0440	acetolactate synthase activity
ES300_RS02120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ES300_RS02135	COG0765	amino acid transport
ES300_RS02160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ES300_RS02165	COG1882	Formate acetyltransferase
ES300_RS02185	COG1940	carbohydrate kinase activity
ES300_RS02185	COG1846	Transcriptional regulator
ES300_RS02190	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS02200	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES300_RS02205	COG2723	6-phospho-beta-galactosidase activity
ES300_RS02210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS02210	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS02215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ES300_RS02220	COG0569	domain protein
ES300_RS02240	COG1122	ATPase activity
ES300_RS02255	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ES300_RS02260	COG0671	phosphoesterase, PA-phosphatase related
ES300_RS02280	COG0504	CTP synthase activity
ES300_RS02285	COG1283	sodium-dependent phosphate transmembrane transporter activity
ES300_RS02305	COG0789	Transcriptional regulator
ES300_RS02310	COG0174	glutamine synthetase
ES300_RS02330	COG4974	Belongs to the 'phage' integrase family
ES300_RS02340	COG4974	Belongs to the 'phage' integrase family
ES300_RS02350	COG0732	type I restriction modification DNA specificity domain
ES300_RS02390	COG0484	heat shock protein binding
ES300_RS02405	COG0537	adenosine 5'-monophosphoramidase activity
ES300_RS02410	COG1131	(ABC) transporter
ES300_RS02435	COG3290	protein histidine kinase activity
ES300_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ES300_RS02450	COG2274	protein secretion by the type I secretion system
ES300_RS02530	COG1266	CAAX protease self-immunity
ES300_RS02550	COG0195	Participates in both transcription termination and antitermination
ES300_RS02555	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ES300_RS02615	COG0519	Catalyzes the synthesis of GMP from XMP
ES300_RS02625	COG0525	valine-tRNA ligase activity
ES300_RS02645	COG3711	transcriptional antiterminator
ES300_RS02650	COG1263	PTS System
ES300_RS02650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS02650	COG2190	(PTS) system
ES300_RS02665	COG0456	acetyltransferase
ES300_RS02670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES300_RS02670	COG0072	phenylalanine-tRNA ligase activity
ES300_RS02685	COG3620	sequence-specific DNA binding
ES300_RS02690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ES300_RS02700	COG1185	polyribonucleotide nucleotidyltransferase activity
ES300_RS02705	COG1045	serine acetyltransferase
ES300_RS02715	COG0215	cysteine-tRNA ligase activity
ES300_RS02720	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ES300_RS02745	COG0577	efflux transmembrane transporter activity
ES300_RS02750	COG1136	(ABC) transporter
ES300_RS02755	COG0577	efflux transmembrane transporter activity
ES300_RS02765	COG0745	RESPONSE REGULATOR receiver
ES300_RS02770	COG5002	protein histidine kinase activity
ES300_RS02775	COG0191	fructose-bisphosphate aldolase activity
ES300_RS02780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ES300_RS02785	COG0765	amino acid transport
ES300_RS02790	COG0765	amino acid transport
ES300_RS02795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS02805	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ES300_RS02805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ES300_RS02835	COG0322	excinuclease ABC activity
ES300_RS02845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS02860	COG1573	uracil-dna glycosylase
ES300_RS02870	COG1114	Component of the transport system for branched-chain amino acids
ES300_RS02875	COG1363	Peptidase, m42
ES300_RS02920	COG4555	ABC transporter
ES300_RS02945	COG1404	Belongs to the peptidase S8 family
ES300_RS02960	COG3775	system Galactitol-specific IIC component
ES300_RS02970	COG3250	beta-galactosidase activity
ES300_RS03000	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ES300_RS03020	COG0785	Cytochrome C biogenesis protein
ES300_RS03025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES300_RS03030	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES300_RS03030	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES300_RS03035	COG4753	response regulator
ES300_RS03035	COG2207	Transcriptional regulator
ES300_RS03040	COG2972	Histidine kinase
ES300_RS03045	COG4475	Protein of unknown function (DUF436)
ES300_RS03050	COG3064	Membrane
ES300_RS03055	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ES300_RS03070	COG1940	carbohydrate kinase activity
ES300_RS03090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ES300_RS03095	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ES300_RS03105	COG0300	oxidoreductase activity
ES300_RS03130	COG1187	pseudouridine synthase activity
ES300_RS03135	COG1217	gtp-binding protein TYPA
ES300_RS03155	COG1136	(ABC) transporter
ES300_RS03170	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ES300_RS03205	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ES300_RS03225	COG1131	(ABC) transporter
ES300_RS03235	COG1126	abc transporter atp-binding protein
ES300_RS03240	COG4215	(ABC) transporter
ES300_RS03250	COG1304	FMN binding
ES300_RS03260	COG1304	FMN binding
ES300_RS03270	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ES300_RS03275	COG0352	thiamine-phosphate diphosphorylase activity
ES300_RS03285	COG4172	Belongs to the ABC transporter superfamily
ES300_RS03295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ES300_RS03310	COG0352	thiamine-phosphate diphosphorylase activity
ES300_RS03330	COG2217	Heavy metal translocating P-type atpase
ES300_RS03335	COG0028	Belongs to the TPP enzyme family
ES300_RS03355	COG1482	cell wall glycoprotein biosynthetic process
ES300_RS03360	COG0733	neurotransmitter:sodium symporter activity
ES300_RS03370	COG0789	Transcriptional regulator
ES300_RS03380	COG2081	HI0933 family
ES300_RS03385	COG1307	EDD domain protein, DegV family
ES300_RS03395	COG2131	deaminase
ES300_RS03400	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ES300_RS03440	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ES300_RS03440	COG0617	tRNA 3'-terminal CCA addition
ES300_RS03440	COG0517	IMP dehydrogenase activity
ES300_RS03450	COG2884	Cell division ATP-binding protein ftsE
ES300_RS03455	COG2177	Part of the ABC transporter FtsEX involved in
ES300_RS03460	COG2190	(PTS) system
ES300_RS03460	COG1263	PTS System
ES300_RS03460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS03475	COG0513	Belongs to the DEAD box helicase family
ES300_RS03485	COG0167	dihydroorotate dehydrogenase activity
ES300_RS03495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ES300_RS03500	COG4470	Protein conserved in bacteria
ES300_RS03515	COG0488	(ABC) transporter
ES300_RS03540	COG1837	Belongs to the UPF0109 family
ES300_RS03565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ES300_RS03565	COG1328	CTP reductase activity
ES300_RS03575	COG4443	Transcriptional Coactivator p15 (PC4)
ES300_RS03580	COG1268	BioY protein
ES300_RS03585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES300_RS03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ES300_RS03595	COG1136	(ABC) transporter
ES300_RS03600	COG0577	efflux transmembrane transporter activity
ES300_RS03605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES300_RS03605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES300_RS03625	COG4989	oxidoreductase activity
ES300_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
ES300_RS03660	COG0745	RESPONSE REGULATOR receiver
ES300_RS03665	COG5002	protein histidine kinase activity
ES300_RS03685	COG0772	Belongs to the SEDS family
ES300_RS03690	COG0693	protein deglycase activity
ES300_RS03700	COG0187	DNA topoisomerase II activity
ES300_RS03730	COG0542	response to heat
ES300_RS03735	COG4703	Protein of unknown function (DUF1797)
ES300_RS03740	COG0765	amino acid transport
ES300_RS03745	COG1126	abc transporter atp-binding protein
ES300_RS03750	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ES300_RS03755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ES300_RS03775	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ES300_RS03825	COG2813	Specifically methylates the guanine in position
ES300_RS03830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ES300_RS03840	COG0295	cytidine deaminase activity
ES300_RS03845	COG1744	ABC transporter substrate-binding protein PnrA-like
ES300_RS03850	COG3845	ABC transporter
ES300_RS03855	COG4603	Belongs to the binding-protein-dependent transport system permease family
ES300_RS03860	COG1079	Belongs to the binding-protein-dependent transport system permease family
ES300_RS03875	COG0187	DNA topoisomerase II activity
ES300_RS03880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ES300_RS03885	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ES300_RS03925	COG0539	negative regulation of cytoplasmic translation
ES300_RS03935	COG1956	GAF domain-containing protein
ES300_RS03940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ES300_RS03955	COG0719	Fe-S assembly protein
ES300_RS03960	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ES300_RS03970	COG0719	Fe-S assembly protein
ES300_RS03975	COG1686	Belongs to the peptidase S11 family
ES300_RS03980	COG0628	permease
ES300_RS03995	COG1349	DNA-binding transcription factor activity
ES300_RS04000	COG1105	Belongs to the carbohydrate kinase PfkB family
ES300_RS04005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS04005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES300_RS04005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ES300_RS04010	COG0697	spore germination
ES300_RS04010	COG1674	ftsk spoiiie
ES300_RS04020	COG1104	cysteine desulfurase activity
ES300_RS04075	COG1438	arginine binding
ES300_RS04095	COG0469	pyruvate kinase activity
ES300_RS04100	COG0582	viral genome integration into host DNA
ES300_RS04130	COG3689	TIGRFAM TIGR03943 family protein
ES300_RS04135	COG0701	Predicted permease
ES300_RS04145	COG2183	response to ionizing radiation
ES300_RS04170	COG1136	(ABC) transporter
ES300_RS04190	COG1982	Orn Lys Arg decarboxylase major
ES300_RS04210	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ES300_RS04230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ES300_RS04235	COG0561	phosphatase activity
ES300_RS04255	COG0583	DNA-binding transcription factor activity
ES300_RS04260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ES300_RS04265	COG0564	pseudouridine synthase activity
ES300_RS04270	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ES300_RS04285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ES300_RS04295	COG0470	DNA polymerase III
ES300_RS04340	COG0528	UMP kinase activity
ES300_RS04350	COG2996	Protein conserved in bacteria
ES300_RS04360	COG1702	phosphate starvation-inducible protein PhoH
ES300_RS04380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES300_RS04385	COG1555	photosystem II stabilization
ES300_RS04385	COG1596	polysaccharide export
ES300_RS04390	COG2333	competence protein COMEC
ES300_RS04390	COG0658	competence protein
ES300_RS04400	COG1131	(ABC) transporter
ES300_RS04430	COG0543	2 iron, 2 sulfur cluster binding
ES300_RS04435	COG0167	dihydroorotate dehydrogenase activity
ES300_RS04440	COG5263	repeat protein
ES300_RS04440	COG4193	domain, Protein
ES300_RS04445	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ES300_RS04455	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ES300_RS04465	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ES300_RS04470	COG0237	dephospho-CoA kinase activity
ES300_RS04475	COG2814	Major facilitator Superfamily
ES300_RS04480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ES300_RS04490	COG0557	exoribonuclease II activity
ES300_RS04500	COG0500	methyltransferase
ES300_RS04500	COG3615	Tellurite resistance protein tehB
ES300_RS04515	COG4122	O-methyltransferase activity
ES300_RS04550	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ES300_RS04570	COG0494	nUDIX hydrolase
ES300_RS04580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ES300_RS04590	COG2176	DNA-directed DNA polymerase activity
ES300_RS04595	COG0584	glycerophosphoryl diester phosphodiesterase
ES300_RS04615	COG0785	Cytochrome C biogenesis protein
ES300_RS04620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES300_RS04625	COG0531	amino acid
ES300_RS04630	COG0803	Belongs to the bacterial solute-binding protein 9 family
ES300_RS04630	COG3443	Belongs to the bacterial solute-binding protein 9 family
ES300_RS04670	COG1970	mechanosensitive ion channel activity
ES300_RS04680	COG4708	membrane
ES300_RS04690	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ES300_RS04700	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ES300_RS04705	COG1942	4-Oxalocrotonate Tautomerase
ES300_RS04710	COG1435	thymidine kinase activity
ES300_RS04715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ES300_RS04720	COG2890	protein-(glutamine-N5) methyltransferase activity
ES300_RS04735	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ES300_RS04745	COG0741	lytic transglycosylase activity
ES300_RS04755	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ES300_RS04780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES300_RS04850	COG1597	lipid kinase activity
ES300_RS04865	COG1396	sequence-specific DNA binding
ES300_RS04870	COG0542	response to heat
ES300_RS04880	COG4581	dead DEAH box helicase
ES300_RS04895	COG0772	Belongs to the SEDS family
ES300_RS04900	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ES300_RS04915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ES300_RS04920	COG0358	DNA primase activity
ES300_RS04925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ES300_RS04930	COG2151	metal-sulfur cluster biosynthetic enzyme
ES300_RS04935	COG0438	transferase activity, transferring glycosyl groups
ES300_RS04940	COG0438	transferase activity, transferring glycosyl groups
ES300_RS04965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ES300_RS04975	COG4109	DRTGG domain
ES300_RS04980	COG0024	Methionine aminopeptidase
ES300_RS04990	COG0210	DNA helicase
ES300_RS05000	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ES300_RS05020	COG1104	cysteine desulfurase activity
ES300_RS05025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ES300_RS05035	COG2357	RelA SpoT domain protein
ES300_RS05045	COG0564	pseudouridine synthase activity
ES300_RS05050	COG0280	phosphate acetyltransferase
ES300_RS05095	COG0196	riboflavin kinase activity
ES300_RS05100	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES300_RS05105	COG1307	EDD domain protein, DegV family
ES300_RS05115	COG0488	(ABC) transporter
ES300_RS05135	COG1523	belongs to the glycosyl hydrolase 13 family
ES300_RS05140	COG1012	belongs to the aldehyde dehydrogenase family
ES300_RS05145	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ES300_RS05155	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ES300_RS05165	COG0560	Phosphoserine phosphatase
ES300_RS05170	COG0560	Phosphoserine phosphatase
ES300_RS05190	COG0582	viral genome integration into host DNA
ES300_RS05225	COG3064	Membrane
ES300_RS05250	COG3843	relaxase mobilization nuclease domain protein
ES300_RS05270	COG0515	serine threonine protein kinase
ES300_RS05275	COG1122	ATPase activity
ES300_RS05290	COG1396	sequence-specific DNA binding
ES300_RS05300	COG0582	viral genome integration into host DNA
ES300_RS05305	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ES300_RS05325	COG0095	Lipoate-protein ligase
ES300_RS05330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES300_RS05335	COG0508	dehydrogenase complex catalyzes the overall conversion of
ES300_RS05340	COG0022	dehydrogenase e1 component
ES300_RS05345	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ES300_RS05350	COG0534	Mate efflux family protein
ES300_RS05360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ES300_RS05365	COG1051	belongs to the nudix hydrolase family
ES300_RS05380	COG1011	Hydrolase
ES300_RS05385	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ES300_RS05400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS05405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ES300_RS05410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ES300_RS05415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ES300_RS05430	COG2723	6-phospho-beta-galactosidase activity
ES300_RS05445	COG3711	transcriptional antiterminator
ES300_RS05455	COG3684	Belongs to the aldolase LacD family
ES300_RS05505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ES300_RS05510	COG0497	DNA recombination
ES300_RS05515	COG1438	arginine binding
ES300_RS05520	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ES300_RS05550	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ES300_RS05570	COG3764	Sortase (surface protein transpeptidase)
ES300_RS05575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ES300_RS05585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ES300_RS05600	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ES300_RS05605	COG5002	protein histidine kinase activity
ES300_RS05610	COG0745	RESPONSE REGULATOR receiver
ES300_RS05615	COG1194	a g-specific adenine glycosylase
ES300_RS05630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ES300_RS05635	COG4684	Psort location CytoplasmicMembrane, score
ES300_RS05645	COG1827	regulation of RNA biosynthetic process
ES300_RS05675	COG0765	amino acid transport
ES300_RS05680	COG1126	abc transporter atp-binding protein
ES300_RS05685	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ES300_RS05690	COG0552	protein localization to endoplasmic reticulum
ES300_RS05695	COG0561	phosphatase activity
ES300_RS05700	COG0561	phosphatase activity
ES300_RS05705	COG1196	nuclear chromosome segregation
ES300_RS05720	COG0516	GMP reductase activity
ES300_RS05730	COG1401	restriction endodeoxyribonuclease activity
ES300_RS05740	COG0066	3-isopropylmalate dehydratase activity
ES300_RS05765	COG3142	Participates in the control of copper homeostasis
ES300_RS05770	COG2832	Protein of unknown function (DUF454)
ES300_RS05775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ES300_RS05785	COG0758	DNA mediated transformation
ES300_RS05790	COG4750	Nucleotidyl transferase
ES300_RS05805	COG1063	alcohol dehydrogenase
ES300_RS05820	COG3475	LICD family
ES300_RS05825	COG3475	LICD family
ES300_RS05835	COG0505	Belongs to the CarA family
ES300_RS05850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ES300_RS05865	COG0488	(ABC) transporter
ES300_RS05875	COG1704	LemA family
ES300_RS05890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ES300_RS05905	COG1078	dGTPase activity
ES300_RS05925	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ES300_RS05930	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ES300_RS05935	COG1605	Chorismate mutase
ES300_RS05935	COG0077	Prephenate dehydratase
ES300_RS05940	COG0716	FMN binding
ES300_RS05945	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ES300_RS05970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ES300_RS06005	COG0295	cytidine deaminase activity
ES300_RS06015	COG2081	HI0933 family
ES300_RS06030	COG0395	ABC-type sugar transport system, permease component
ES300_RS06035	COG4209	transmembrane transport
ES300_RS06040	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ES300_RS06070	COG0577	efflux transmembrane transporter activity
ES300_RS06070	COG1136	(ABC) transporter
ES300_RS06080	COG0515	serine threonine protein kinase
ES300_RS06130	COG0402	S-adenosylhomocysteine deaminase activity
ES300_RS06140	COG1132	(ABC) transporter
ES300_RS06145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES300_RS06145	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ES300_RS06160	COG4862	establishment of competence for transformation
ES300_RS06175	COG1215	transferase activity, transferring glycosyl groups
ES300_RS06185	COG3475	LICD family
ES300_RS06195	COG0077	Prephenate dehydratase
ES300_RS06200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ES300_RS06210	COG3679	Belongs to the UPF0342 family
ES300_RS06215	COG0287	Prephenate dehydrogenase
ES300_RS06240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ES300_RS06250	COG1131	(ABC) transporter
ES300_RS06260	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ES300_RS06290	COG3842	ATPase activity
ES300_RS06305	COG3527	Alpha-acetolactate decarboxylase
ES300_RS06310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ES300_RS06315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS06320	COG0704	Plays a role in the regulation of phosphate uptake
ES300_RS06325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES300_RS06330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES300_RS06335	COG0581	inorganic phosphate transmembrane transporter activity
ES300_RS06340	COG0573	inorganic phosphate transmembrane transporter activity
ES300_RS06345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ES300_RS06350	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ES300_RS06350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ES300_RS06355	COG0483	inositol monophosphate 1-phosphatase activity
ES300_RS06365	COG1393	Belongs to the ArsC family
ES300_RS06375	COG0647	UMP catabolic process
ES300_RS06385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ES300_RS06435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ES300_RS06445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ES300_RS06465	COG1131	(ABC) transporter
ES300_RS06480	COG0826	peptidase U32
ES300_RS06510	COG1132	(ABC) transporter
ES300_RS06525	COG1129	ABC transporter
ES300_RS06570	COG2188	Transcriptional regulator
ES300_RS06575	COG0697	spore germination
ES300_RS06580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ES300_RS06595	COG0561	phosphatase activity
ES300_RS06620	COG0492	ferredoxin-NADP+ reductase activity
ES300_RS06630	COG1126	abc transporter atp-binding protein
ES300_RS06640	COG1393	Belongs to the ArsC family
ES300_RS06660	COG1272	protein, Hemolysin III
ES300_RS06690	COG0431	NADPH-dependent FMN reductase
ES300_RS06690	COG1053	succinate dehydrogenase
ES300_RS06690	COG3976	FMN-binding domain protein
ES300_RS06700	COG0751	glycine-tRNA ligase activity
ES300_RS06715	COG0656	L-ascorbic acid biosynthetic process
ES300_RS06720	COG0726	polysaccharide deacetylase
ES300_RS06750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ES300_RS06775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ES300_RS06790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ES300_RS06795	COG1126	abc transporter atp-binding protein
ES300_RS06805	COG0457	Tetratricopeptide repeat
ES300_RS06810	COG0628	permease
ES300_RS06815	COG2706	6-phosphogluconolactonase activity
ES300_RS06875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ES300_RS06900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ES300_RS06905	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ES300_RS06910	COG0626	cystathionine gamma-synthase activity
ES300_RS06915	COG1132	(ABC) transporter
ES300_RS06925	COG4166	transmembrane transport
ES300_RS06930	COG2244	polysaccharide biosynthetic process
ES300_RS06935	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ES300_RS06960	COG2827	Endonuclease containing a URI domain
ES300_RS06965	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ES300_RS06970	COG1098	S1 RNA binding domain
ES300_RS06980	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ES300_RS06985	COG0629	single-stranded DNA binding
ES300_RS06995	COG0017	Asparaginyl-tRNA synthetase
ES300_RS07005	COG0436	Aminotransferase
ES300_RS07035	COG0242	peptide deformylase activity
ES300_RS07040	COG0625	glutathione transferase activity
ES300_RS07050	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ES300_RS07055	COG0488	(ABC) transporter
ES300_RS07070	COG1307	EDD domain protein, DegV family
ES300_RS07090	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ES300_RS07100	COG1481	regulation of sporulation
ES300_RS07105	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ES300_RS07115	COG0251	oxidation-reduction process
ES300_RS07135	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ES300_RS07145	COG4193	domain, Protein
ES300_RS07145	COG5263	repeat protein
ES300_RS07155	COG3935	DnaD domain protein
ES300_RS07170	COG2226	methyltransferase
ES300_RS07180	COG3842	ATPase activity
ES300_RS07190	COG1335	isochorismatase
ES300_RS07195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ES300_RS07200	COG0513	Belongs to the DEAD box helicase family
ES300_RS07205	COG2223	nitrite transmembrane transporter activity
ES300_RS07210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ES300_RS07215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ES300_RS07220	COG3442	glutamine amidotransferase
ES300_RS07225	COG0006	proline dipeptidase activity
ES300_RS07235	COG4720	Psort location CytoplasmicMembrane, score
ES300_RS07240	COG0351	phosphomethylpyrimidine kinase
ES300_RS07260	COG2824	Alkylphosphonate utilization operon protein PhnA
ES300_RS07280	COG0463	Glycosyl transferase, family 2
ES300_RS07285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ES300_RS07295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ES300_RS07300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ES300_RS07305	COG2384	SAM-dependent methyltransferase
ES300_RS07310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ES300_RS07315	COG0204	Acyl-transferase
ES300_RS07350	COG5002	protein histidine kinase activity
ES300_RS07355	COG0745	RESPONSE REGULATOR receiver
ES300_RS07370	COG1959	2 iron, 2 sulfur cluster binding
ES300_RS07420	COG3590	peptidase
ES300_RS07435	COG0803	Belongs to the bacterial solute-binding protein 9 family
ES300_RS07440	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ES300_RS07450	COG0577	efflux transmembrane transporter activity
ES300_RS07450	COG1136	(ABC) transporter
ES300_RS07475	COG3599	regulation of cell shape
ES300_RS07495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ES300_RS07515	COG1051	belongs to the nudix hydrolase family
ES300_RS07520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ES300_RS07535	COG0768	penicillin binding
ES300_RS07550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ES300_RS07570	COG2731	YhcH YjgK YiaL family protein
ES300_RS07575	COG0395	ABC-type sugar transport system, permease component
ES300_RS07580	COG1175	transmembrane transport
ES300_RS07590	COG1263	PTS System
ES300_RS07590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS07590	COG2190	(PTS) system
ES300_RS07600	COG0673	inositol 2-dehydrogenase activity
ES300_RS07605	COG4409	exo-alpha-(2->6)-sialidase activity
ES300_RS07615	COG1175	transmembrane transport
ES300_RS07620	COG1653	transport
ES300_RS07645	COG3458	cephalosporin-C deacetylase activity
ES300_RS07650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ES300_RS07665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ES300_RS07670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ES300_RS07675	COG0653	protein targeting
ES300_RS07685	COG1131	(ABC) transporter
ES300_RS07715	COG0778	Nitroreductase
ES300_RS07720	COG1484	DNA-dependent DNA replication
ES300_RS07735	COG1725	Transcriptional regulator
ES300_RS07740	COG1131	(ABC) transporter
ES300_RS07750	COG1668	transmembrane transport
ES300_RS07755	COG4152	abc transporter atp-binding protein
ES300_RS07775	COG1940	carbohydrate kinase activity
ES300_RS07780	COG1263	PTS System
ES300_RS07780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS07780	COG2190	(PTS) system
ES300_RS07785	COG1621	beta-fructofuranosidase activity
ES300_RS07790	COG1609	Transcriptional regulator
ES300_RS07800	COG3425	synthase
ES300_RS07825	COG2815	serine threonine protein kinase
ES300_RS07825	COG0515	serine threonine protein kinase
ES300_RS07830	COG0631	protein serine/threonine phosphatase activity
ES300_RS07835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ES300_RS07835	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ES300_RS07845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ES300_RS07855	COG0194	GDP metabolic process
ES300_RS07875	COG2226	methyltransferase
ES300_RS07880	COG0799	negative regulation of ribosome biogenesis
ES300_RS07890	COG1713	HD superfamily hydrolase involved in NAD metabolism
ES300_RS07895	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ES300_RS07900	COG1534	Rna-binding protein
ES300_RS07905	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ES300_RS07920	COG0668	transmembrane transport
ES300_RS07945	COG3118	belongs to the thioredoxin family
ES300_RS07950	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ES300_RS07970	COG1164	Oligoendopeptidase f
ES300_RS07975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ES300_RS08035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ES300_RS08045	COG1621	beta-fructofuranosidase activity
ES300_RS08050	COG1653	transport
ES300_RS08055	COG0395	ABC-type sugar transport system, permease component
ES300_RS08060	COG4209	transmembrane transport
ES300_RS08070	COG3711	transcriptional antiterminator
ES300_RS08075	COG2261	transglycosylase associated protein
ES300_RS08095	COG3237	CsbD-like
ES300_RS08120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ES300_RS08130	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS08135	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES300_RS08140	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS08150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS08155	COG1940	carbohydrate kinase activity
ES300_RS08155	COG1846	Transcriptional regulator
ES300_RS08165	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ES300_RS08210	COG0512	Glutamine amidotransferase of anthranilate synthase
ES300_RS08215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ES300_RS08235	COG1285	pathogenesis
ES300_RS08240	COG1178	ABC-type Fe3 transport system permease component
ES300_RS08260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ES300_RS08265	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ES300_RS08270	COG0704	Plays a role in the regulation of phosphate uptake
ES300_RS08285	COG5434	Belongs to the glycosyl hydrolase 28 family
ES300_RS08295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ES300_RS08300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ES300_RS08305	COG1132	(ABC) transporter
ES300_RS08310	COG1132	(ABC) transporter
ES300_RS08325	COG0708	Exodeoxyribonuclease III
ES300_RS08345	COG2233	PERMEase
ES300_RS08370	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ES300_RS08375	COG1609	Transcriptional regulator
ES300_RS08380	COG1063	alcohol dehydrogenase
ES300_RS08385	COG0789	Transcriptional regulator
ES300_RS08390	COG1230	cation diffusion facilitator family transporter
ES300_RS08400	COG3201	nicotinamide mononucleotide transporter
ES300_RS08405	COG1174	glycine betaine transport
ES300_RS08430	COG1363	Peptidase, m42
ES300_RS08435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ES300_RS08440	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ES300_RS08445	COG4605	iron ion homeostasis
ES300_RS08450	COG4604	ABC transporter, ATP-binding protein
ES300_RS08455	COG4607	ABC-type enterochelin transport system periplasmic component
ES300_RS08460	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ES300_RS08465	COG1187	pseudouridine synthase activity
ES300_RS08485	COG0517	IMP dehydrogenase activity
ES300_RS08495	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ES300_RS08510	COG0366	Alpha amylase catalytic
ES300_RS08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS08515	COG1263	PTS System
ES300_RS08520	COG2188	Transcriptional regulator
ES300_RS08525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ES300_RS08530	COG4120	Belongs to the binding-protein-dependent transport system permease family
ES300_RS08540	COG4608	Belongs to the ABC transporter superfamily
ES300_RS08545	COG0444	Belongs to the ABC transporter superfamily
ES300_RS08550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ES300_RS08555	COG0601	transmembrane transport
ES300_RS08560	COG4166	transmembrane transport
ES300_RS08570	COG0366	Alpha amylase catalytic
ES300_RS08575	COG0395	ABC-type sugar transport system, permease component
ES300_RS08580	COG1175	transmembrane transport
ES300_RS08585	COG1653	transport
ES300_RS08590	COG3345	alpha-galactosidase
ES300_RS08595	COG2207	Transcriptional regulator
ES300_RS08600	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ES300_RS08600	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ES300_RS08715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ES300_RS08765	COG4221	oxidoreductase activity
ES300_RS08770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ES300_RS08775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ES300_RS08815	COG1132	(ABC) transporter
ES300_RS08895	COG5263	repeat protein
ES300_RS08895	COG5632	N-Acetylmuramoyl-L-alanine amidase
ES300_RS08915	COG1316	TRANSCRIPTIONal
ES300_RS08925	COG0802	atpase or kinase
ES300_RS08980	COG0577	efflux transmembrane transporter activity
ES300_RS08980	COG1136	(ABC) transporter
ES300_RS09010	COG1253	flavin adenine dinucleotide binding
ES300_RS09025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ES300_RS09035	COG3480	Lon protease (S16) C-terminal proteolytic domain
ES300_RS09040	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ES300_RS09045	COG0742	ribosomal rna small subunit methyltransferase
ES300_RS09060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ES300_RS09065	COG1254	Belongs to the acylphosphatase family
ES300_RS09075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ES300_RS09085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ES300_RS09100	COG1564	THIamine pyrophosphokinase
ES300_RS09110	COG1162	GTPase activity
ES300_RS09115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ES300_RS09145	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ES300_RS09150	COG0084	hydrolase, TatD family'
ES300_RS09165	COG0436	Aminotransferase
ES300_RS09175	COG0589	response to stress
ES300_RS09180	COG0561	phosphatase activity
ES300_RS09185	COG0252	asparaginase activity
ES300_RS09195	COG1609	Transcriptional regulator
ES300_RS09200	COG2197	response regulator
ES300_RS09205	COG4585	Histidine kinase
ES300_RS09210	COG0842	Transport permease protein
ES300_RS09215	COG1131	(ABC) transporter
ES300_RS09315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ES300_RS09320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES300_RS09325	COG0564	pseudouridine synthase activity
ES300_RS09335	COG0577	efflux transmembrane transporter activity
ES300_RS09345	COG0157	Belongs to the NadC ModD family
ES300_RS09360	COG1129	ABC transporter
ES300_RS09365	COG2188	Transcriptional regulator
ES300_RS09370	COG2723	6-phospho-beta-galactosidase activity
ES300_RS09375	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ES300_RS09385	COG1447	Phosphotransferase system cellobiose-specific component IIA
ES300_RS09390	COG1454	alcohol dehydrogenase
ES300_RS09390	COG1012	belongs to the aldehyde dehydrogenase family
ES300_RS09400	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ES300_RS09410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ES300_RS09430	COG3623	hexulose-6-phosphate isomerase
ES300_RS09440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS09450	COG3037	sugar-specific permease SgaT UlaA
ES300_RS09460	COG1847	R3H domain protein
ES300_RS09465	COG0706	membrane insertase activity
ES300_RS09510	COG4537	Required for transformation and DNA binding
ES300_RS09515	COG1459	type II secretion system
ES300_RS09520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ES300_RS09530	COG1063	alcohol dehydrogenase
ES300_RS09560	COG3759	membrane
ES300_RS09575	COG0546	phosphoglycolate phosphatase activity
ES300_RS09580	COG0534	Mate efflux family protein
ES300_RS09610	COG1674	ftsk spoiiie
ES300_RS09645	COG0582	viral genome integration into host DNA
ES300_RS09660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ES300_RS09750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ES300_RS09765	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ES300_RS09770	COG1132	(ABC) transporter
ES300_RS09780	COG1132	(ABC) transporter
ES300_RS09790	COG1438	arginine binding
ES300_RS09810	COG0745	RESPONSE REGULATOR receiver
ES300_RS09815	COG5002	protein histidine kinase activity
ES300_RS09820	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ES300_RS09825	COG0573	inorganic phosphate transmembrane transporter activity
ES300_RS09835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ES300_RS09840	COG0704	Plays a role in the regulation of phosphate uptake
ES300_RS09860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ES300_RS09870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ES300_RS09885	COG0697	spore germination
ES300_RS09890	COG4499	WXG100 protein secretion system (Wss), protein YukC
ES300_RS09890	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ES300_RS09900	COG2217	Heavy metal translocating P-type atpase
ES300_RS09910	COG2226	methyltransferase
ES300_RS09925	COG0058	SHG alpha-glucan phosphorylase activity
ES300_RS09930	COG1640	4-alpha-glucanotransferase
ES300_RS09935	COG2182	Extracellular solute-binding protein
ES300_RS09940	COG1175	transmembrane transport
ES300_RS09945	COG3833	ABC-type maltose transport systems, permease component
ES300_RS09950	COG5521	maltodextrose utilization protein MalA
ES300_RS09955	COG1609	Transcriptional regulator
ES300_RS09965	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ES300_RS10000	COG1476	TRANSCRIPTIONal
ES300_RS10030	COG2151	metal-sulfur cluster biosynthetic enzyme
ES300_RS10045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ES300_RS10050	COG3959	Transketolase, thiamine diphosphate binding domain
ES300_RS10065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ES300_RS10085	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ES300_RS10120	COG0383	alpha-mannosidase activity
ES300_RS10130	COG3537	Alpha-1,2-mannosidase
ES300_RS10150	COG0549	Belongs to the carbamate kinase family
ES300_RS10155	COG1288	antiporter activity
ES300_RS10160	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ES300_RS10170	COG3583	domain protein
ES300_RS10170	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ES300_RS10170	COG3064	Membrane
ES300_RS10185	COG1454	alcohol dehydrogenase
ES300_RS10190	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ES300_RS10205	COG3716	PTS system mannose fructose sorbose family IID component
ES300_RS10215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ES300_RS10235	COG1070	Carbohydrate kinase
ES300_RS10245	COG0803	Belongs to the bacterial solute-binding protein 9 family
ES300_RS10245	COG3443	Belongs to the bacterial solute-binding protein 9 family
ES300_RS10250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ES300_RS10255	COG1121	(ABC) transporter
ES300_RS10260	COG1846	Transcriptional regulator
ES300_RS10265	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ES300_RS10275	COG1696	Membrane protein involved in D-alanine export
ES300_RS10290	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ES300_RS10295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ES300_RS10315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ES300_RS10335	COG1755	Isoprenylcysteine carboxyl methyltransferase
ES300_RS10340	COG5002	protein histidine kinase activity
ES300_RS10345	COG0745	RESPONSE REGULATOR receiver
ES300_RS10350	COG0542	response to heat
ES300_RS10355	COG4463	regulation of RNA biosynthetic process
ES300_RS10360	COG1116	anion transmembrane transporter activity
ES300_RS10365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ES300_RS10370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ES300_RS10390	COG0305	Participates in initiation and elongation during chromosome replication
ES300_RS10410	COG1040	competence protein
ES300_RS10415	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ES300_RS10420	COG1739	Uncharacterized protein family UPF0029
ES300_RS10455	COG3942	CHAP domain
ES300_RS10465	COG1792	Involved in formation and maintenance of cell shape
ES300_RS10470	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ES300_RS10475	COG1122	ATPase activity
ES300_RS10480	COG1122	ATPase activity
ES300_RS10485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ES300_RS10495	COG0612	Peptidase, M16
ES300_RS10500	COG0612	Peptidase, M16
ES300_RS10505	COG2501	S4 domain
ES300_RS10515	COG0516	GMP reductase activity
ES300_RS10515	COG0517	IMP dehydrogenase activity
ES300_RS10520	COG0180	Tryptophanyl-tRNA synthetase
ES300_RS10525	COG0488	(ABC) transporter
ES300_RS10540	COG1511	domain protein
ES300_RS10585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ES300_RS10590	COG1475	DNA binding