locus-tag	class	description
SPT_RS00040	COG0592	DNA-directed DNA polymerase activity
SPT_RS00190	COG3645	SOS response
SPT_RS00195	COG4974	Belongs to the 'phage' integrase family
SPT_RS00200	COG0012	GTP binding
SPT_RS00210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
SPT_RS00215	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
SPT_RS00240	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
SPT_RS00245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
SPT_RS00310	COG0756	dUTP diphosphatase activity
SPT_RS00320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
SPT_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SPT_RS00355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SPT_RS00355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SPT_RS00360	COG1832	CoA-binding protein
SPT_RS00365	COG2855	membrane
SPT_RS00370	COG0436	Aminotransferase
SPT_RS00375	COG1381	Involved in DNA repair and RecF pathway recombination
SPT_RS00385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SPT_RS00410	COG2274	protein secretion by the type I secretion system
SPT_RS00415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPT_RS00430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
SPT_RS00435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
SPT_RS00445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
SPT_RS00460	COG0151	Belongs to the GarS family
SPT_RS00465	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
SPT_RS00480	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
SPT_RS00485	COG3583	domain protein
SPT_RS00485	COG3064	Membrane
SPT_RS00485	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SPT_RS00500	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS00505	COG3715	PTS system
SPT_RS00510	COG3716	PTS system mannose fructose sorbose family IID component
SPT_RS00520	COG2222	sugar isomerase
SPT_RS00530	COG2514	catechol 2,3-dioxygenase activity
SPT_RS00535	COG1937	Protein conserved in bacteria
SPT_RS00560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SPT_RS00565	COG0569	domain protein
SPT_RS00570	COG1215	transferase activity, transferring glycosyl groups
SPT_RS00590	COG5002	protein histidine kinase activity
SPT_RS00615	COG4209	transmembrane transport
SPT_RS00620	COG0395	ABC-type sugar transport system, permease component
SPT_RS00630	COG1653	transport
SPT_RS00655	COG1136	(ABC) transporter
SPT_RS00655	COG0577	efflux transmembrane transporter activity
SPT_RS00675	COG1695	Transcriptional regulator
SPT_RS00700	COG0546	phosphoglycolate phosphatase activity
SPT_RS00705	COG1760	l-serine dehydratase
SPT_RS00710	COG1760	l-serine dehydratase
SPT_RS00715	COG1705	Flagellar rod assembly protein muramidase FlgJ
SPT_RS00715	COG1388	LysM domain
SPT_RS00740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS00745	COG0137	argininosuccinate synthase activity
SPT_RS00845	COG0494	nUDIX hydrolase
SPT_RS00850	COG0445	tRNA wobble uridine modification
SPT_RS00885	COG1214	PFAM Peptidase M22, glycoprotease
SPT_RS00925	COG0438	transferase activity, transferring glycosyl groups
SPT_RS00960	COG1396	sequence-specific DNA binding
SPT_RS00995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS01000	COG1464	Belongs to the NlpA lipoprotein family
SPT_RS01005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SPT_RS01010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
SPT_RS01030	COG2972	Histidine kinase
SPT_RS01035	COG2207	Transcriptional regulator
SPT_RS01035	COG4753	response regulator
SPT_RS01045	COG1780	Probably involved in ribonucleotide reductase function
SPT_RS01080	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SPT_RS01080	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
SPT_RS01100	COG2818	Glycosylase
SPT_RS01125	COG0582	viral genome integration into host DNA
SPT_RS01200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
SPT_RS01205	COG0006	proline dipeptidase activity
SPT_RS01210	COG1393	Belongs to the ArsC family
SPT_RS01235	COG0285	dihydrofolate synthase activity
SPT_RS01245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
SPT_RS01310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
SPT_RS01335	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
SPT_RS01375	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
SPT_RS01390	COG0201	protein transport
SPT_RS01400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
SPT_RS01405	COG0257	Belongs to the bacterial ribosomal protein bL36 family
SPT_RS01415	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
SPT_RS01420	COG0202	RNA polymerase activity
SPT_RS01430	COG3830	Belongs to the UPF0237 family
SPT_RS01450	COG1178	ABC-type Fe3 transport system permease component
SPT_RS01455	COG3842	ATPase activity
SPT_RS01475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SPT_RS01480	COG1349	DNA-binding transcription factor activity
SPT_RS01490	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPT_RS01495	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS01500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS01505	COG1882	Formate acetyltransferase
SPT_RS01555	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
SPT_RS01560	COG4589	Belongs to the CDS family
SPT_RS01565	COG0750	zinc metalloprotease
SPT_RS01575	COG2723	6-phospho-beta-galactosidase activity
SPT_RS01580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
SPT_RS01590	COG1523	belongs to the glycosyl hydrolase 13 family
SPT_RS01610	COG2176	DNA-directed DNA polymerase activity
SPT_RS01630	COG2309	aminopeptidase activity
SPT_RS01635	COG2261	transglycosylase associated protein
SPT_RS01645	COG1187	pseudouridine synthase activity
SPT_RS01655	COG3579	cysteine-type endopeptidase activity
SPT_RS01660	COG3716	PTS system mannose fructose sorbose family IID component
SPT_RS01665	COG3715	PTS system
SPT_RS01675	COG1064	alcohol dehydrogenase
SPT_RS01680	COG0561	phosphatase activity
SPT_RS01685	COG2252	PERMEase
SPT_RS01695	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
SPT_RS01700	COG0285	dihydrofolate synthase activity
SPT_RS01710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
SPT_RS01710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
SPT_RS01720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
SPT_RS01760	COG1674	ftsk spoiiie
SPT_RS01795	COG2723	6-phospho-beta-galactosidase activity
SPT_RS01810	COG3711	transcriptional antiterminator
SPT_RS01810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPT_RS01825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS01840	COG0386	Belongs to the glutathione peroxidase family
SPT_RS01845	COG5492	domain, Protein
SPT_RS01870	COG1028	Short-chain dehydrogenase reductase Sdr
SPT_RS01880	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
SPT_RS01885	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS01890	COG3715	PTS system
SPT_RS01895	COG3716	PTS system mannose fructose sorbose family IID component
SPT_RS01910	COG1609	Transcriptional regulator
SPT_RS01940	COG4839	cell division protein FtsL
SPT_RS01945	COG0768	penicillin binding
SPT_RS01970	COG0366	Alpha amylase catalytic
SPT_RS01975	COG4166	transmembrane transport
SPT_RS02020	COG3475	LICD family
SPT_RS02040	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
SPT_RS02045	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
SPT_RS02055	COG1088	dTDP-glucose 4,6-dehydratase activity
SPT_RS02060	COG1091	dTDP-4-dehydrorhamnose reductase activity
SPT_RS02070	COG4166	transmembrane transport
SPT_RS02075	COG0366	Alpha amylase catalytic
SPT_RS02080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPT_RS02105	COG0116	Belongs to the methyltransferase superfamily
SPT_RS02115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
SPT_RS02120	COG0745	RESPONSE REGULATOR receiver
SPT_RS02165	COG1304	FMN binding
SPT_RS02175	COG4585	Histidine kinase
SPT_RS02180	COG2197	response regulator
SPT_RS02205	COG0582	viral genome integration into host DNA
SPT_RS02215	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SPT_RS02220	COG0681	Belongs to the peptidase S26 family
SPT_RS02245	COG1115	amino acid carrier protein
SPT_RS02270	COG0527	aspartate kinase activity
SPT_RS02275	COG1024	Enoyl-CoA hydratase
SPT_RS02280	COG1846	Transcriptional regulator
SPT_RS02290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
SPT_RS02300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
SPT_RS02305	COG1028	Short-chain dehydrogenase reductase Sdr
SPT_RS02310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
SPT_RS02325	COG0439	Biotin carboxylase
SPT_RS02330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
SPT_RS02365	COG1063	alcohol dehydrogenase
SPT_RS02395	COG0227	Belongs to the bacterial ribosomal protein bL28 family
SPT_RS02405	COG1461	Dihydroxyacetone kinase
SPT_RS02410	COG0028	Belongs to the TPP enzyme family
SPT_RS02415	COG0440	acetolactate synthase activity
SPT_RS02435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
SPT_RS02450	COG0765	amino acid transport
SPT_RS02480	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
SPT_RS02485	COG1882	Formate acetyltransferase
SPT_RS02560	COG1846	Transcriptional regulator
SPT_RS02560	COG1940	carbohydrate kinase activity
SPT_RS02565	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS02575	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPT_RS02580	COG2723	6-phospho-beta-galactosidase activity
SPT_RS02585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS02585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS02590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
SPT_RS02595	COG0569	domain protein
SPT_RS02615	COG1122	ATPase activity
SPT_RS02630	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
SPT_RS02635	COG0671	phosphoesterase, PA-phosphatase related
SPT_RS02645	COG1247	-acetyltransferase
SPT_RS02660	COG0504	CTP synthase activity
SPT_RS02665	COG1283	sodium-dependent phosphate transmembrane transporter activity
SPT_RS02685	COG0789	Transcriptional regulator
SPT_RS02690	COG0174	glutamine synthetase
SPT_RS02700	COG0732	type I restriction modification DNA specificity domain
SPT_RS02705	COG0732	type I restriction modification DNA specificity domain
SPT_RS02750	COG0484	heat shock protein binding
SPT_RS02765	COG0537	adenosine 5'-monophosphoramidase activity
SPT_RS02770	COG1131	(ABC) transporter
SPT_RS02775	COG4473	ABC transporter
SPT_RS02800	COG3290	protein histidine kinase activity
SPT_RS02815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPT_RS02885	COG1266	CAAX protease self-immunity
SPT_RS02905	COG0195	Participates in both transcription termination and antitermination
SPT_RS02910	COG2740	Nucleic-acid-binding protein implicated in transcription termination
SPT_RS02975	COG0519	Catalyzes the synthesis of GMP from XMP
SPT_RS02985	COG0525	valine-tRNA ligase activity
SPT_RS03005	COG2801	Transposase and inactivated derivatives
SPT_RS03020	COG3711	transcriptional antiterminator
SPT_RS03025	COG2190	(PTS) system
SPT_RS03025	COG1263	PTS System
SPT_RS03025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS03040	COG0456	acetyltransferase
SPT_RS03045	COG0072	phenylalanine-tRNA ligase activity
SPT_RS03045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPT_RS03065	COG3620	sequence-specific DNA binding
SPT_RS03075	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
SPT_RS03085	COG1045	serine acetyltransferase
SPT_RS03095	COG0215	cysteine-tRNA ligase activity
SPT_RS03100	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
SPT_RS03120	COG0577	efflux transmembrane transporter activity
SPT_RS03125	COG1136	(ABC) transporter
SPT_RS03130	COG0577	efflux transmembrane transporter activity
SPT_RS03135	COG0745	RESPONSE REGULATOR receiver
SPT_RS03140	COG5002	protein histidine kinase activity
SPT_RS03145	COG0191	fructose-bisphosphate aldolase activity
SPT_RS03150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
SPT_RS03155	COG0765	amino acid transport
SPT_RS03160	COG0765	amino acid transport
SPT_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS03175	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
SPT_RS03175	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
SPT_RS03215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS03230	COG1573	uracil-dna glycosylase
SPT_RS03240	COG1114	Component of the transport system for branched-chain amino acids
SPT_RS03245	COG1363	Peptidase, m42
SPT_RS03285	COG4555	ABC transporter
SPT_RS03315	COG1404	Belongs to the peptidase S8 family
SPT_RS03330	COG3775	system Galactitol-specific IIC component
SPT_RS03340	COG3250	beta-galactosidase activity
SPT_RS03375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
SPT_RS03395	COG0785	Cytochrome C biogenesis protein
SPT_RS03400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPT_RS03405	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPT_RS03405	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPT_RS03410	COG4753	response regulator
SPT_RS03410	COG2207	Transcriptional regulator
SPT_RS03415	COG2972	Histidine kinase
SPT_RS03425	COG3064	Membrane
SPT_RS03430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SPT_RS03445	COG1940	carbohydrate kinase activity
SPT_RS03465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
SPT_RS03470	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SPT_RS03480	COG0300	oxidoreductase activity
SPT_RS03495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
SPT_RS03505	COG1187	pseudouridine synthase activity
SPT_RS03510	COG1217	gtp-binding protein TYPA
SPT_RS03530	COG1136	(ABC) transporter
SPT_RS03545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
SPT_RS03555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
SPT_RS03580	COG1131	(ABC) transporter
SPT_RS03585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS03595	COG1126	abc transporter atp-binding protein
SPT_RS03600	COG1129	ABC transporter
SPT_RS03620	COG0765	amino acid transport
SPT_RS03630	COG1304	FMN binding
SPT_RS03635	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
SPT_RS03645	COG1304	FMN binding
SPT_RS03660	COG0352	thiamine-phosphate diphosphorylase activity
SPT_RS03670	COG4172	Belongs to the ABC transporter superfamily
SPT_RS03680	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
SPT_RS03695	COG0352	thiamine-phosphate diphosphorylase activity
SPT_RS03715	COG2217	Heavy metal translocating P-type atpase
SPT_RS03720	COG0028	Belongs to the TPP enzyme family
SPT_RS03730	COG3335	DDE superfamily endonuclease
SPT_RS03740	COG2723	6-phospho-beta-galactosidase activity
SPT_RS03745	COG1482	cell wall glycoprotein biosynthetic process
SPT_RS03750	COG0733	neurotransmitter:sodium symporter activity
SPT_RS03755	COG0789	Transcriptional regulator
SPT_RS03765	COG2081	HI0933 family
SPT_RS03770	COG1307	EDD domain protein, DegV family
SPT_RS03780	COG2131	deaminase
SPT_RS03785	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
SPT_RS03825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SPT_RS03825	COG0617	tRNA 3'-terminal CCA addition
SPT_RS03825	COG0517	IMP dehydrogenase activity
SPT_RS03830	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
SPT_RS03835	COG2884	Cell division ATP-binding protein ftsE
SPT_RS03840	COG2177	Part of the ABC transporter FtsEX involved in
SPT_RS03845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS03845	COG2190	(PTS) system
SPT_RS03845	COG1263	PTS System
SPT_RS03855	COG0513	Belongs to the DEAD box helicase family
SPT_RS03865	COG0167	dihydroorotate dehydrogenase activity
SPT_RS03875	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
SPT_RS03880	COG4470	Protein conserved in bacteria
SPT_RS03895	COG0488	(ABC) transporter
SPT_RS03920	COG1837	Belongs to the UPF0109 family
SPT_RS03940	COG3335	DDE superfamily endonuclease
SPT_RS03965	COG0726	polysaccharide deacetylase
SPT_RS03970	COG0656	L-ascorbic acid biosynthetic process
SPT_RS03995	COG3976	FMN-binding domain protein
SPT_RS03995	COG1053	succinate dehydrogenase
SPT_RS03995	COG0431	NADPH-dependent FMN reductase
SPT_RS04025	COG1272	protein, Hemolysin III
SPT_RS04040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
SPT_RS04045	COG1393	Belongs to the ArsC family
SPT_RS04055	COG1126	abc transporter atp-binding protein
SPT_RS04065	COG0492	ferredoxin-NADP+ reductase activity
SPT_RS04095	COG0561	phosphatase activity
SPT_RS04110	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
SPT_RS04115	COG0697	spore germination
SPT_RS04120	COG2188	Transcriptional regulator
SPT_RS04150	COG1132	(ABC) transporter
SPT_RS04155	COG1132	(ABC) transporter
SPT_RS04170	COG1129	ABC transporter
SPT_RS04200	COG0826	peptidase U32
SPT_RS04205	COG0826	peptidase U32
SPT_RS04210	COG1131	(ABC) transporter
SPT_RS04230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
SPT_RS04240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SPT_RS04260	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
SPT_RS04295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
SPT_RS04305	COG0647	UMP catabolic process
SPT_RS04315	COG1393	Belongs to the ArsC family
SPT_RS04325	COG0483	inositol monophosphate 1-phosphatase activity
SPT_RS04330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SPT_RS04330	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
SPT_RS04335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SPT_RS04340	COG0573	inorganic phosphate transmembrane transporter activity
SPT_RS04345	COG0581	inorganic phosphate transmembrane transporter activity
SPT_RS04350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPT_RS04355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPT_RS04360	COG0704	Plays a role in the regulation of phosphate uptake
SPT_RS04365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS04370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
SPT_RS04375	COG3527	Alpha-acetolactate decarboxylase
SPT_RS04390	COG3842	ATPase activity
SPT_RS04430	COG4555	ABC transporter
SPT_RS04440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
SPT_RS04465	COG0287	Prephenate dehydrogenase
SPT_RS04480	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
SPT_RS04485	COG0077	Prephenate dehydratase
SPT_RS04495	COG3475	LICD family
SPT_RS04505	COG1215	transferase activity, transferring glycosyl groups
SPT_RS04540	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPT_RS04540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
SPT_RS04545	COG1132	(ABC) transporter
SPT_RS04555	COG0402	S-adenosylhomocysteine deaminase activity
SPT_RS04575	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
SPT_RS04585	COG3335	DDE superfamily endonuclease
SPT_RS04600	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
SPT_RS04605	COG0716	FMN binding
SPT_RS04610	COG1605	Chorismate mutase
SPT_RS04610	COG0077	Prephenate dehydratase
SPT_RS04615	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SPT_RS04620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
SPT_RS04645	COG1078	dGTPase activity
SPT_RS04660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
SPT_RS04675	COG1704	LemA family
SPT_RS04685	COG0488	(ABC) transporter
SPT_RS04695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
SPT_RS04710	COG0505	Belongs to the CarA family
SPT_RS04720	COG3475	LICD family
SPT_RS04725	COG3475	LICD family
SPT_RS04740	COG1063	alcohol dehydrogenase
SPT_RS04755	COG4750	Nucleotidyl transferase
SPT_RS04760	COG0758	DNA mediated transformation
SPT_RS04770	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
SPT_RS04775	COG2832	Protein of unknown function (DUF454)
SPT_RS04780	COG3142	Participates in the control of copper homeostasis
SPT_RS04800	COG0473	3-isopropylmalate dehydrogenase activity
SPT_RS04810	COG0066	3-isopropylmalate dehydratase activity
SPT_RS04825	COG1401	restriction endodeoxyribonuclease activity
SPT_RS04850	COG1196	nuclear chromosome segregation
SPT_RS04855	COG0561	phosphatase activity
SPT_RS04860	COG0561	phosphatase activity
SPT_RS04865	COG0552	protein localization to endoplasmic reticulum
SPT_RS04870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
SPT_RS04875	COG1126	abc transporter atp-binding protein
SPT_RS04880	COG0765	amino acid transport
SPT_RS04905	COG2816	NAD+ diphosphatase activity
SPT_RS04910	COG1827	regulation of RNA biosynthetic process
SPT_RS04920	COG4684	Psort location CytoplasmicMembrane, score
SPT_RS04925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
SPT_RS04940	COG1194	a g-specific adenine glycosylase
SPT_RS04945	COG0745	RESPONSE REGULATOR receiver
SPT_RS04950	COG5002	protein histidine kinase activity
SPT_RS04955	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
SPT_RS04970	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
SPT_RS04985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SPT_RS04990	COG3764	Sortase (surface protein transpeptidase)
SPT_RS05010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
SPT_RS05045	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
SPT_RS05050	COG1438	arginine binding
SPT_RS05055	COG0497	DNA recombination
SPT_RS05060	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
SPT_RS05120	COG3684	Belongs to the aldolase LacD family
SPT_RS05125	COG3711	transcriptional antiterminator
SPT_RS05140	COG2723	6-phospho-beta-galactosidase activity
SPT_RS05155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SPT_RS05160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
SPT_RS05165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
SPT_RS05170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPT_RS05235	COG0681	Belongs to the peptidase S26 family
SPT_RS05245	COG4509	Sortase family
SPT_RS05260	COG1970	mechanosensitive ion channel activity
SPT_RS05270	COG4708	membrane
SPT_RS05280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
SPT_RS05295	COG1942	4-Oxalocrotonate Tautomerase
SPT_RS05300	COG1435	thymidine kinase activity
SPT_RS05310	COG2890	protein-(glutamine-N5) methyltransferase activity
SPT_RS05335	COG0741	lytic transglycosylase activity
SPT_RS05345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SPT_RS05365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPT_RS05370	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPT_RS05445	COG1597	lipid kinase activity
SPT_RS05490	COG0772	Belongs to the SEDS family
SPT_RS05495	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
SPT_RS05515	COG0358	DNA primase activity
SPT_RS05520	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
SPT_RS05525	COG2151	metal-sulfur cluster biosynthetic enzyme
SPT_RS05530	COG0438	transferase activity, transferring glycosyl groups
SPT_RS05535	COG0438	transferase activity, transferring glycosyl groups
SPT_RS05575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SPT_RS05585	COG4109	DRTGG domain
SPT_RS05590	COG0024	Methionine aminopeptidase
SPT_RS05610	COG0210	DNA helicase
SPT_RS05620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SPT_RS05640	COG1104	cysteine desulfurase activity
SPT_RS05645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
SPT_RS05655	COG2357	RelA SpoT domain protein
SPT_RS05665	COG0564	pseudouridine synthase activity
SPT_RS05670	COG0280	phosphate acetyltransferase
SPT_RS05720	COG0196	riboflavin kinase activity
SPT_RS05725	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SPT_RS05730	COG1307	EDD domain protein, DegV family
SPT_RS05740	COG0488	(ABC) transporter
SPT_RS05760	COG1523	belongs to the glycosyl hydrolase 13 family
SPT_RS05770	COG1012	belongs to the aldehyde dehydrogenase family
SPT_RS05775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
SPT_RS05785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
SPT_RS05795	COG0560	Phosphoserine phosphatase
SPT_RS05850	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
SPT_RS05850	COG3583	domain protein
SPT_RS05855	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SPT_RS05875	COG0095	Lipoate-protein ligase
SPT_RS05880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPT_RS05885	COG0508	dehydrogenase complex catalyzes the overall conversion of
SPT_RS05890	COG0022	dehydrogenase e1 component
SPT_RS05895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
SPT_RS05900	COG0534	Mate efflux family protein
SPT_RS05910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
SPT_RS05915	COG1051	belongs to the nudix hydrolase family
SPT_RS05930	COG1011	Hydrolase
SPT_RS05935	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
SPT_RS05945	COG0803	Belongs to the bacterial solute-binding protein 9 family
SPT_RS05945	COG3443	Belongs to the bacterial solute-binding protein 9 family
SPT_RS05950	COG0531	amino acid
SPT_RS05955	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPT_RS05960	COG0785	Cytochrome C biogenesis protein
SPT_RS05995	COG0584	glycerophosphoryl diester phosphodiesterase
SPT_RS06000	COG2176	DNA-directed DNA polymerase activity
SPT_RS06010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
SPT_RS06020	COG0494	nUDIX hydrolase
SPT_RS06040	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
SPT_RS06065	COG4122	O-methyltransferase activity
SPT_RS06080	COG0500	methyltransferase
SPT_RS06080	COG3615	Tellurite resistance protein tehB
SPT_RS06090	COG0557	exoribonuclease II activity
SPT_RS06105	COG2814	Major facilitator Superfamily
SPT_RS06110	COG0237	dephospho-CoA kinase activity
SPT_RS06115	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SPT_RS06125	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
SPT_RS06135	COG1293	RNA-binding protein homologous to eukaryotic snRNP
SPT_RS06140	COG4193	domain, Protein
SPT_RS06140	COG5263	repeat protein
SPT_RS06145	COG0167	dihydroorotate dehydrogenase activity
SPT_RS06150	COG0543	2 iron, 2 sulfur cluster binding
SPT_RS06180	COG1131	(ABC) transporter
SPT_RS06190	COG2333	competence protein COMEC
SPT_RS06190	COG0658	competence protein
SPT_RS06195	COG1555	photosystem II stabilization
SPT_RS06195	COG1596	polysaccharide export
SPT_RS06200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
SPT_RS06205	COG0686	Belongs to the AlaDH PNT family
SPT_RS06210	COG0686	Belongs to the AlaDH PNT family
SPT_RS06215	COG0686	Belongs to the AlaDH PNT family
SPT_RS06230	COG1702	phosphate starvation-inducible protein PhoH
SPT_RS06240	COG2996	Protein conserved in bacteria
SPT_RS06250	COG0528	UMP kinase activity
SPT_RS06270	COG0470	DNA polymerase III
SPT_RS06280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
SPT_RS06295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
SPT_RS06300	COG0564	pseudouridine synthase activity
SPT_RS06305	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
SPT_RS06310	COG0583	DNA-binding transcription factor activity
SPT_RS06330	COG0561	phosphatase activity
SPT_RS06335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
SPT_RS06355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
SPT_RS06370	COG1982	Orn Lys Arg decarboxylase major
SPT_RS06385	COG0577	efflux transmembrane transporter activity
SPT_RS06390	COG1136	(ABC) transporter
SPT_RS06415	COG2183	response to ionizing radiation
SPT_RS06425	COG0701	Predicted permease
SPT_RS06430	COG3689	TIGRFAM TIGR03943 family protein
SPT_RS06470	COG0469	pyruvate kinase activity
SPT_RS06490	COG1438	arginine binding
SPT_RS06500	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
SPT_RS06560	COG1104	cysteine desulfurase activity
SPT_RS06570	COG0697	spore germination
SPT_RS06570	COG1674	ftsk spoiiie
SPT_RS06575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPT_RS06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPT_RS06575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPT_RS06580	COG1105	Belongs to the carbohydrate kinase PfkB family
SPT_RS06585	COG1349	DNA-binding transcription factor activity
SPT_RS06595	COG0628	permease
SPT_RS06600	COG1686	Belongs to the peptidase S11 family
SPT_RS06610	COG0719	Fe-S assembly protein
SPT_RS06620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
SPT_RS06625	COG0719	Fe-S assembly protein
SPT_RS06640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
SPT_RS06645	COG1956	GAF domain-containing protein
SPT_RS06660	COG0539	negative regulation of cytoplasmic translation
SPT_RS06695	COG4166	transmembrane transport
SPT_RS06700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
SPT_RS06705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
SPT_RS06715	COG0187	DNA topoisomerase II activity
SPT_RS06725	COG2801	Transposase and inactivated derivatives
SPT_RS06740	COG1079	Belongs to the binding-protein-dependent transport system permease family
SPT_RS06745	COG4603	Belongs to the binding-protein-dependent transport system permease family
SPT_RS06750	COG3845	ABC transporter
SPT_RS06755	COG1744	ABC transporter substrate-binding protein PnrA-like
SPT_RS06760	COG0295	cytidine deaminase activity
SPT_RS06770	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
SPT_RS06775	COG2813	Specifically methylates the guanine in position
SPT_RS06820	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
SPT_RS06840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
SPT_RS06845	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
SPT_RS06850	COG1126	abc transporter atp-binding protein
SPT_RS06855	COG0765	amino acid transport
SPT_RS06860	COG4703	Protein of unknown function (DUF1797)
SPT_RS06865	COG0542	response to heat
SPT_RS06880	COG0494	nUDIX hydrolase
SPT_RS06890	COG2801	Transposase and inactivated derivatives
SPT_RS06910	COG3335	DDE superfamily endonuclease
SPT_RS06925	COG0187	DNA topoisomerase II activity
SPT_RS06935	COG0693	protein deglycase activity
SPT_RS06940	COG0772	Belongs to the SEDS family
SPT_RS06960	COG5002	protein histidine kinase activity
SPT_RS06965	COG0745	RESPONSE REGULATOR receiver
SPT_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
SPT_RS07000	COG4989	oxidoreductase activity
SPT_RS07020	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPT_RS07020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPT_RS07025	COG0577	efflux transmembrane transporter activity
SPT_RS07030	COG1136	(ABC) transporter
SPT_RS07035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
SPT_RS07040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPT_RS07045	COG1268	BioY protein
SPT_RS07055	COG4443	Transcriptional Coactivator p15 (PC4)
SPT_RS07065	COG1328	CTP reductase activity
SPT_RS07065	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
SPT_RS07095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPT_RS07130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
SPT_RS07140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
SPT_RS07145	COG1126	abc transporter atp-binding protein
SPT_RS07155	COG0457	Tetratricopeptide repeat
SPT_RS07160	COG0628	permease
SPT_RS07165	COG2706	6-phosphogluconolactonase activity
SPT_RS07230	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
SPT_RS07255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
SPT_RS07260	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
SPT_RS07265	COG0626	cystathionine gamma-synthase activity
SPT_RS07270	COG1132	(ABC) transporter
SPT_RS07275	COG1132	(ABC) transporter
SPT_RS07285	COG4166	transmembrane transport
SPT_RS07290	COG2244	polysaccharide biosynthetic process
SPT_RS07295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
SPT_RS07320	COG2827	Endonuclease containing a URI domain
SPT_RS07325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
SPT_RS07330	COG1098	S1 RNA binding domain
SPT_RS07340	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
SPT_RS07345	COG0629	single-stranded DNA binding
SPT_RS07355	COG0017	Asparaginyl-tRNA synthetase
SPT_RS07365	COG0436	Aminotransferase
SPT_RS07390	COG3711	transcriptional antiterminator
SPT_RS07410	COG0242	peptide deformylase activity
SPT_RS07415	COG0625	glutathione transferase activity
SPT_RS07425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
SPT_RS07430	COG0488	(ABC) transporter
SPT_RS07435	COG0617	tRNA 3'-terminal CCA addition
SPT_RS07445	COG1307	EDD domain protein, DegV family
SPT_RS07465	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
SPT_RS07480	COG1481	regulation of sporulation
SPT_RS07485	COG0391	Required for morphogenesis under gluconeogenic growth conditions
SPT_RS07495	COG0251	oxidation-reduction process
SPT_RS07515	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
SPT_RS07535	COG3935	DnaD domain protein
SPT_RS07550	COG2226	methyltransferase
SPT_RS07560	COG3842	ATPase activity
SPT_RS07570	COG1335	isochorismatase
SPT_RS07580	COG0513	Belongs to the DEAD box helicase family
SPT_RS07585	COG2223	nitrite transmembrane transporter activity
SPT_RS07590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
SPT_RS07595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SPT_RS07600	COG3442	glutamine amidotransferase
SPT_RS07605	COG0006	proline dipeptidase activity
SPT_RS07610	COG2801	Transposase and inactivated derivatives
SPT_RS07615	COG2801	Transposase and inactivated derivatives
SPT_RS07630	COG4720	Psort location CytoplasmicMembrane, score
SPT_RS07635	COG0351	phosphomethylpyrimidine kinase
SPT_RS07660	COG2824	Alkylphosphonate utilization operon protein PhnA
SPT_RS07680	COG0463	Glycosyl transferase, family 2
SPT_RS07685	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SPT_RS07690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
SPT_RS07695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
SPT_RS07700	COG2384	SAM-dependent methyltransferase
SPT_RS07715	COG2801	Transposase and inactivated derivatives
SPT_RS07720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SPT_RS07725	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
SPT_RS07730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPT_RS07730	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
SPT_RS07730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPT_RS07735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
SPT_RS07755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
SPT_RS07760	COG0204	Acyl-transferase
SPT_RS07775	COG2910	NAD(P)H-binding
SPT_RS07800	COG5002	protein histidine kinase activity
SPT_RS07805	COG0745	RESPONSE REGULATOR receiver
SPT_RS07820	COG1959	2 iron, 2 sulfur cluster binding
SPT_RS07880	COG3590	peptidase
SPT_RS07895	COG0803	Belongs to the bacterial solute-binding protein 9 family
SPT_RS07900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
SPT_RS07910	COG0577	efflux transmembrane transporter activity
SPT_RS07910	COG1136	(ABC) transporter
SPT_RS07955	COG3599	regulation of cell shape
SPT_RS07975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
SPT_RS07995	COG1051	belongs to the nudix hydrolase family
SPT_RS08000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
SPT_RS08015	COG0768	penicillin binding
SPT_RS08030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
SPT_RS08050	COG2731	YhcH YjgK YiaL family protein
SPT_RS08055	COG0395	ABC-type sugar transport system, permease component
SPT_RS08060	COG1175	transmembrane transport
SPT_RS08070	COG1263	PTS System
SPT_RS08070	COG2190	(PTS) system
SPT_RS08070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS08080	COG0673	inositol 2-dehydrogenase activity
SPT_RS08085	COG4409	exo-alpha-(2->6)-sialidase activity
SPT_RS08095	COG1175	transmembrane transport
SPT_RS08100	COG1653	transport
SPT_RS08130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
SPT_RS08145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SPT_RS08150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
SPT_RS08165	COG1131	(ABC) transporter
SPT_RS08195	COG0778	Nitroreductase
SPT_RS08200	COG1484	DNA-dependent DNA replication
SPT_RS08215	COG1725	Transcriptional regulator
SPT_RS08220	COG1131	(ABC) transporter
SPT_RS08230	COG1668	transmembrane transport
SPT_RS08235	COG4152	abc transporter atp-binding protein
SPT_RS08255	COG1940	carbohydrate kinase activity
SPT_RS08260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS08260	COG1263	PTS System
SPT_RS08260	COG2190	(PTS) system
SPT_RS08265	COG1621	beta-fructofuranosidase activity
SPT_RS08270	COG1609	Transcriptional regulator
SPT_RS08280	COG3425	synthase
SPT_RS08310	COG2815	serine threonine protein kinase
SPT_RS08310	COG0515	serine threonine protein kinase
SPT_RS08315	COG0631	protein serine/threonine phosphatase activity
SPT_RS08320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
SPT_RS08320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
SPT_RS08330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
SPT_RS08340	COG0194	GDP metabolic process
SPT_RS08370	COG2226	methyltransferase
SPT_RS08375	COG0799	negative regulation of ribosome biogenesis
SPT_RS08385	COG1713	HD superfamily hydrolase involved in NAD metabolism
SPT_RS08390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
SPT_RS08395	COG1534	Rna-binding protein
SPT_RS08400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
SPT_RS08415	COG0668	transmembrane transport
SPT_RS08440	COG3118	belongs to the thioredoxin family
SPT_RS08445	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
SPT_RS08455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPT_RS08475	COG1164	Oligoendopeptidase f
SPT_RS08480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
SPT_RS08540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
SPT_RS08550	COG1621	beta-fructofuranosidase activity
SPT_RS08555	COG1653	transport
SPT_RS08560	COG0395	ABC-type sugar transport system, permease component
SPT_RS08565	COG4209	transmembrane transport
SPT_RS08575	COG3711	transcriptional antiterminator
SPT_RS08600	COG3237	CsbD-like
SPT_RS08615	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
SPT_RS08655	COG0512	Glutamine amidotransferase of anthranilate synthase
SPT_RS08660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
SPT_RS08685	COG1285	pathogenesis
SPT_RS08690	COG1178	ABC-type Fe3 transport system permease component
SPT_RS08710	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
SPT_RS08715	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
SPT_RS08720	COG0704	Plays a role in the regulation of phosphate uptake
SPT_RS08735	COG5434	Belongs to the glycosyl hydrolase 28 family
SPT_RS08740	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
SPT_RS08745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
SPT_RS08750	COG1132	(ABC) transporter
SPT_RS08755	COG1132	(ABC) transporter
SPT_RS08775	COG0708	Exodeoxyribonuclease III
SPT_RS08795	COG2233	PERMEase
SPT_RS08820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
SPT_RS08825	COG1609	Transcriptional regulator
SPT_RS08830	COG1063	alcohol dehydrogenase
SPT_RS08835	COG0789	Transcriptional regulator
SPT_RS08840	COG1230	cation diffusion facilitator family transporter
SPT_RS08850	COG3201	nicotinamide mononucleotide transporter
SPT_RS08855	COG1174	glycine betaine transport
SPT_RS08880	COG1363	Peptidase, m42
SPT_RS08895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
SPT_RS08900	COG4605	iron ion homeostasis
SPT_RS08905	COG4604	ABC transporter, ATP-binding protein
SPT_RS08910	COG4607	ABC-type enterochelin transport system periplasmic component
SPT_RS08920	COG1187	pseudouridine synthase activity
SPT_RS08940	COG0517	IMP dehydrogenase activity
SPT_RS08950	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
SPT_RS08970	COG0366	Alpha amylase catalytic
SPT_RS08975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS08975	COG1263	PTS System
SPT_RS08980	COG2188	Transcriptional regulator
SPT_RS09010	COG4608	Belongs to the ABC transporter superfamily
SPT_RS09015	COG0444	Belongs to the ABC transporter superfamily
SPT_RS09020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
SPT_RS09025	COG0601	transmembrane transport
SPT_RS09030	COG4166	transmembrane transport
SPT_RS09040	COG0366	Alpha amylase catalytic
SPT_RS09050	COG0395	ABC-type sugar transport system, permease component
SPT_RS09055	COG1175	transmembrane transport
SPT_RS09060	COG1653	transport
SPT_RS09065	COG3345	alpha-galactosidase
SPT_RS09070	COG2207	Transcriptional regulator
SPT_RS09075	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
SPT_RS09075	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
SPT_RS09190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
SPT_RS09240	COG4221	oxidoreductase activity
SPT_RS09245	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
SPT_RS09250	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
SPT_RS09295	COG1132	(ABC) transporter
SPT_RS09350	COG3842	ATPase activity
SPT_RS09360	COG1285	pathogenesis
SPT_RS09420	COG5263	repeat protein
SPT_RS09420	COG5632	N-Acetylmuramoyl-L-alanine amidase
SPT_RS09440	COG1316	TRANSCRIPTIONal
SPT_RS09450	COG0802	atpase or kinase
SPT_RS09480	COG1674	ftsk spoiiie
SPT_RS09485	COG2946	Replication initiation factor
SPT_RS09515	COG0741	lytic transglycosylase activity
SPT_RS09515	COG0791	NLP P60 protein
SPT_RS09555	COG0488	(ABC) transporter
SPT_RS09605	COG0577	efflux transmembrane transporter activity
SPT_RS09605	COG1136	(ABC) transporter
SPT_RS09635	COG1253	flavin adenine dinucleotide binding
SPT_RS09650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
SPT_RS09655	COG3480	Lon protease (S16) C-terminal proteolytic domain
SPT_RS09665	COG0742	ribosomal rna small subunit methyltransferase
SPT_RS09680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
SPT_RS09685	COG1254	Belongs to the acylphosphatase family
SPT_RS09695	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
SPT_RS09705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
SPT_RS09720	COG1564	THIamine pyrophosphokinase
SPT_RS09730	COG1162	GTPase activity
SPT_RS09755	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
SPT_RS09760	COG0084	hydrolase, TatD family'
SPT_RS09775	COG0436	Aminotransferase
SPT_RS09785	COG0589	response to stress
SPT_RS09790	COG0561	phosphatase activity
SPT_RS09795	COG0252	asparaginase activity
SPT_RS09805	COG1609	Transcriptional regulator
SPT_RS09810	COG2197	response regulator
SPT_RS09815	COG4585	Histidine kinase
SPT_RS09820	COG0842	Transport permease protein
SPT_RS09825	COG1131	(ABC) transporter
SPT_RS09930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SPT_RS09935	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPT_RS09940	COG0564	pseudouridine synthase activity
SPT_RS09950	COG0577	efflux transmembrane transporter activity
SPT_RS09970	COG0157	Belongs to the NadC ModD family
SPT_RS09980	COG4133	protoheme IX ABC transporter activity
SPT_RS09985	COG2188	Transcriptional regulator
SPT_RS09990	COG2723	6-phospho-beta-galactosidase activity
SPT_RS09995	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
SPT_RS10005	COG1447	Phosphotransferase system cellobiose-specific component IIA
SPT_RS10010	COG1012	belongs to the aldehyde dehydrogenase family
SPT_RS10010	COG1454	alcohol dehydrogenase
SPT_RS10020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
SPT_RS10030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
SPT_RS10050	COG3623	hexulose-6-phosphate isomerase
SPT_RS10060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPT_RS10070	COG3037	sugar-specific permease SgaT UlaA
SPT_RS10080	COG1847	R3H domain protein
SPT_RS10085	COG0706	membrane insertase activity
SPT_RS10130	COG4537	Required for transformation and DNA binding
SPT_RS10135	COG1459	type II secretion system
SPT_RS10140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
SPT_RS10150	COG1063	alcohol dehydrogenase
SPT_RS10175	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
SPT_RS10180	COG3759	membrane
SPT_RS10195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
SPT_RS10195	COG0131	Imidazoleglycerol-phosphate dehydratase
SPT_RS10200	COG0534	Mate efflux family protein
SPT_RS10315	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
SPT_RS10320	COG1132	(ABC) transporter
SPT_RS10330	COG1132	(ABC) transporter
SPT_RS10340	COG1438	arginine binding
SPT_RS10360	COG0745	RESPONSE REGULATOR receiver
SPT_RS10365	COG5002	protein histidine kinase activity
SPT_RS10370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
SPT_RS10375	COG0573	inorganic phosphate transmembrane transporter activity
SPT_RS10385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
SPT_RS10390	COG0704	Plays a role in the regulation of phosphate uptake
SPT_RS10410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
SPT_RS10420	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
SPT_RS10435	COG0697	spore germination
SPT_RS10440	COG4499	WXG100 protein secretion system (Wss), protein YukC
SPT_RS10440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
SPT_RS10450	COG2217	Heavy metal translocating P-type atpase
SPT_RS10460	COG2226	methyltransferase
SPT_RS10480	COG0058	SHG alpha-glucan phosphorylase activity
SPT_RS10485	COG1640	4-alpha-glucanotransferase
SPT_RS10490	COG2182	Extracellular solute-binding protein
SPT_RS10495	COG1175	transmembrane transport
SPT_RS10500	COG3833	ABC-type maltose transport systems, permease component
SPT_RS10505	COG5521	maltodextrose utilization protein MalA
SPT_RS10510	COG1609	Transcriptional regulator
SPT_RS10515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
SPT_RS10550	COG1476	TRANSCRIPTIONal
SPT_RS10575	COG1396	sequence-specific DNA binding
SPT_RS10580	COG2151	metal-sulfur cluster biosynthetic enzyme
SPT_RS10595	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
SPT_RS10600	COG3959	Transketolase, thiamine diphosphate binding domain
SPT_RS10615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
SPT_RS10635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
SPT_RS10675	COG0383	alpha-mannosidase activity
SPT_RS10685	COG3537	Alpha-1,2-mannosidase
SPT_RS10705	COG0549	Belongs to the carbamate kinase family
SPT_RS10710	COG1288	antiporter activity
SPT_RS10715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
SPT_RS10730	COG3064	Membrane
SPT_RS10730	COG3525	Glycosyl hydrolase, family 20, catalytic domain
SPT_RS10730	COG3583	domain protein
SPT_RS10745	COG1454	alcohol dehydrogenase
SPT_RS10765	COG3716	PTS system mannose fructose sorbose family IID component
SPT_RS10775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
SPT_RS10795	COG1070	Carbohydrate kinase
SPT_RS10805	COG3443	Belongs to the bacterial solute-binding protein 9 family
SPT_RS10805	COG0803	Belongs to the bacterial solute-binding protein 9 family
SPT_RS10810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
SPT_RS10815	COG1121	(ABC) transporter
SPT_RS10820	COG1846	Transcriptional regulator
SPT_RS10835	COG1696	Membrane protein involved in D-alanine export
SPT_RS10850	COG2211	Major facilitator Superfamily
SPT_RS10855	COG3344	reverse transcriptase
SPT_RS10875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
SPT_RS10880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
SPT_RS10900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
SPT_RS10925	COG1755	Isoprenylcysteine carboxyl methyltransferase
SPT_RS10930	COG5002	protein histidine kinase activity
SPT_RS10935	COG0745	RESPONSE REGULATOR receiver
SPT_RS10945	COG0542	response to heat
SPT_RS10950	COG4463	regulation of RNA biosynthetic process
SPT_RS10955	COG1116	anion transmembrane transporter activity
SPT_RS10960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
SPT_RS10965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
SPT_RS10985	COG0305	Participates in initiation and elongation during chromosome replication
SPT_RS11005	COG1040	competence protein
SPT_RS11010	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
SPT_RS11015	COG1739	Uncharacterized protein family UPF0029
SPT_RS11030	COG3335	DDE superfamily endonuclease
SPT_RS11050	COG3942	CHAP domain
SPT_RS11060	COG1792	Involved in formation and maintenance of cell shape
SPT_RS11065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
SPT_RS11070	COG1122	ATPase activity
SPT_RS11075	COG1122	ATPase activity
SPT_RS11080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
SPT_RS11090	COG0612	Peptidase, M16
SPT_RS11095	COG0612	Peptidase, M16
SPT_RS11100	COG2501	S4 domain
SPT_RS11110	COG0517	IMP dehydrogenase activity
SPT_RS11110	COG0516	GMP reductase activity
SPT_RS11115	COG0180	Tryptophanyl-tRNA synthetase
SPT_RS11120	COG0488	(ABC) transporter
SPT_RS11130	COG1511	domain protein
SPT_RS11135	COG1511	domain protein
SPT_RS11180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
SPT_RS11185	COG1475	DNA binding
SPT_RS11220	COG2274	protein secretion by the type I secretion system
SPT_RS11225	COG2274	protein secretion by the type I secretion system