locus-tag	class	description
C11O2_RS00010	COG0592	DNA-directed DNA polymerase activity
C11O2_RS00020	COG0012	GTP binding
C11O2_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C11O2_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C11O2_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C11O2_RS00065	COG0531	amino acid
C11O2_RS00245	COG3942	CHAP domain
C11O2_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C11O2_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C11O2_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C11O2_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C11O2_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C11O2_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C11O2_RS00355	COG1454	alcohol dehydrogenase
C11O2_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
C11O2_RS00360	COG1064	alcohol dehydrogenase
C11O2_RS00365	COG0534	Mate efflux family protein
C11O2_RS00475	COG0201	protein transport
C11O2_RS00620	COG1121	(ABC) transporter
C11O2_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C11O2_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C11O2_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C11O2_RS00665	COG1459	type II secretion system
C11O2_RS00670	COG4537	Required for transformation and DNA binding
C11O2_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C11O2_RS00715	COG1363	Peptidase, m42
C11O2_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C11O2_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C11O2_RS00745	COG1428	Deoxynucleoside kinase
C11O2_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C11O2_RS00785	COG4509	Sortase family
C11O2_RS00795	COG4372	Transposase
C11O2_RS00825	COG2031	fatty acid transporter
C11O2_RS00840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C11O2_RS00855	COG0251	oxidation-reduction process
C11O2_RS00870	COG1269	ATP hydrolysis coupled proton transport
C11O2_RS00875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C11O2_RS00885	COG1527	subunit (C
C11O2_RS00890	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
C11O2_RS00925	COG1744	ABC transporter substrate-binding protein PnrA-like
C11O2_RS00970	COG0626	cystathionine gamma-synthase activity
C11O2_RS01000	COG3623	hexulose-6-phosphate isomerase
C11O2_RS01025	COG3448	diguanylate cyclase activity
C11O2_RS01025	COG4175	Glycine betaine
C11O2_RS01035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C11O2_RS01035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C11O2_RS01055	COG3969	phosphoadenosine phosphosulfate
C11O2_RS01060	COG1475	DNA binding
C11O2_RS01085	COG0157	Belongs to the NadC ModD family
C11O2_RS01110	COG1268	BioY protein
C11O2_RS01115	COG1234	tRNA 3'-trailer cleavage
C11O2_RS01150	COG5433	transposase activity
C11O2_RS01155	COG0803	Belongs to the bacterial solute-binding protein 9 family
C11O2_RS01175	COG1122	ATPase activity
C11O2_RS01185	COG0601	transmembrane transport
C11O2_RS01225	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C11O2_RS01230	COG0512	Glutamine amidotransferase of anthranilate synthase
C11O2_RS01235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C11O2_RS01250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C11O2_RS01255	COG2190	(PTS) system
C11O2_RS01255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C11O2_RS01255	COG1263	PTS System
C11O2_RS01295	COG3842	ATPase activity
C11O2_RS01310	COG1523	belongs to the glycosyl hydrolase 13 family
C11O2_RS01320	COG1862	Preprotein translocase
C11O2_RS01330	COG4589	Belongs to the CDS family
C11O2_RS01350	COG1846	Transcriptional regulator
C11O2_RS01380	COG3711	transcriptional antiterminator
C11O2_RS01390	COG3037	sugar-specific permease SgaT UlaA
C11O2_RS01395	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C11O2_RS01410	COG1045	serine acetyltransferase
C11O2_RS01430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C11O2_RS01440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C11O2_RS01460	COG1476	TRANSCRIPTIONal
C11O2_RS01465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C11O2_RS01520	COG1447	Phosphotransferase system cellobiose-specific component IIA
C11O2_RS01525	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C11O2_RS01525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C11O2_RS01545	COG2274	protein secretion by the type I secretion system
C11O2_RS01550	COG1136	(ABC) transporter
C11O2_RS01555	COG0577	efflux transmembrane transporter activity
C11O2_RS01570	COG1929	Belongs to the glycerate kinase type-1 family
C11O2_RS01620	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C11O2_RS01625	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C11O2_RS01630	COG1534	Rna-binding protein
C11O2_RS01640	COG1713	HD superfamily hydrolase involved in NAD metabolism
C11O2_RS01645	COG0799	negative regulation of ribosome biogenesis
C11O2_RS01650	COG2226	methyltransferase
C11O2_RS01670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C11O2_RS01675	COG1464	Belongs to the NlpA lipoprotein family
C11O2_RS01690	COG1114	Component of the transport system for branched-chain amino acids
C11O2_RS01700	COG0569	domain protein
C11O2_RS01705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C11O2_RS01715	COG1704	LemA family
C11O2_RS01730	COG0745	RESPONSE REGULATOR receiver
C11O2_RS01750	COG1484	DNA-dependent DNA replication
C11O2_RS01760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C11O2_RS01780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C11O2_RS01795	COG1254	Belongs to the acylphosphatase family
C11O2_RS01805	COG5433	transposase activity
C11O2_RS01810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C11O2_RS01865	COG1187	pseudouridine synthase activity
C11O2_RS01880	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C11O2_RS01885	COG0671	phosphoesterase, PA-phosphatase related
C11O2_RS01890	COG1242	4 iron, 4 sulfur cluster binding
C11O2_RS01895	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C11O2_RS01900	COG1253	flavin adenine dinucleotide binding
C11O2_RS01905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C11O2_RS01920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C11O2_RS01925	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C11O2_RS01930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C11O2_RS01935	COG1120	ATPase activity
C11O2_RS01945	COG2244	polysaccharide biosynthetic process
C11O2_RS01980	COG0470	DNA polymerase III
C11O2_RS02010	COG1393	Belongs to the ArsC family
C11O2_RS02015	COG0708	Exodeoxyribonuclease III
C11O2_RS02025	COG1304	FMN binding
C11O2_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
C11O2_RS02120	COG0673	inositol 2-dehydrogenase activity
C11O2_RS02135	COG0494	nUDIX hydrolase
C11O2_RS02145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C11O2_RS02235	COG1702	phosphate starvation-inducible protein PhoH
C11O2_RS02240	COG1573	uracil-dna glycosylase
C11O2_RS02250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C11O2_RS02345	COG0433	COG0433 Predicted ATPase
C11O2_RS02350	COG2814	Major facilitator Superfamily
C11O2_RS02365	COG0557	exoribonuclease II activity
C11O2_RS02395	COG0463	Glycosyl transferase, family 2
C11O2_RS02405	COG0778	Nitroreductase
C11O2_RS02410	COG0006	proline dipeptidase activity
C11O2_RS02415	COG1609	Transcriptional regulator
C11O2_RS02425	COG0438	transferase activity, transferring glycosyl groups
C11O2_RS02435	COG4555	ABC transporter
C11O2_RS02455	COG0183	Belongs to the thiolase family
C11O2_RS02470	COG0745	RESPONSE REGULATOR receiver
C11O2_RS02475	COG5002	protein histidine kinase activity
C11O2_RS02480	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C11O2_RS02490	COG1196	nuclear chromosome segregation
C11O2_RS02505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C11O2_RS02530	COG0561	phosphatase activity
C11O2_RS02535	COG0561	phosphatase activity
C11O2_RS02540	COG0552	protein localization to endoplasmic reticulum
C11O2_RS02545	COG0477	Major facilitator Superfamily
C11O2_RS02550	COG3711	transcriptional antiterminator
C11O2_RS02555	COG2190	(PTS) system
C11O2_RS02555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C11O2_RS02555	COG1263	PTS System
C11O2_RS02565	COG3689	TIGRFAM TIGR03943 family protein
C11O2_RS02570	COG0701	Predicted permease
C11O2_RS02580	COG2183	response to ionizing radiation
C11O2_RS02625	COG0826	peptidase U32
C11O2_RS02630	COG4443	Transcriptional Coactivator p15 (PC4)
C11O2_RS02675	COG0386	Belongs to the glutathione peroxidase family
C11O2_RS02680	COG1164	Oligoendopeptidase f
C11O2_RS02690	COG0772	Belongs to the SEDS family
C11O2_RS02725	COG1078	dGTPase activity
C11O2_RS02740	COG1609	Transcriptional regulator
C11O2_RS02750	COG3716	PTS system mannose fructose sorbose family IID component
C11O2_RS02755	COG3715	PTS system
C11O2_RS02760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C11O2_RS02780	COG1028	Short-chain dehydrogenase reductase Sdr
C11O2_RS02795	COG0800	Aldolase
C11O2_RS02800	COG0546	phosphoglycolate phosphatase activity
C11O2_RS02805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C11O2_RS02815	COG2884	Cell division ATP-binding protein ftsE
C11O2_RS02820	COG2177	Part of the ABC transporter FtsEX involved in
C11O2_RS02840	COG1199	ATP-dependent helicase activity
C11O2_RS02840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C11O2_RS02845	COG0436	Aminotransferase
C11O2_RS02880	COG2188	Transcriptional regulator
C11O2_RS02885	COG2222	sugar isomerase
C11O2_RS02895	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C11O2_RS02900	COG0716	FMN binding
C11O2_RS02910	COG0038	chloride channel
C11O2_RS03005	COG1131	(ABC) transporter
C11O2_RS03030	COG4708	membrane
C11O2_RS03040	COG1597	lipid kinase activity
C11O2_RS03125	COG0577	efflux transmembrane transporter activity
C11O2_RS03135	COG2321	neutral zinc metallopeptidase
C11O2_RS03150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C11O2_RS03160	COG1970	mechanosensitive ion channel activity
C11O2_RS03165	COG0358	DNA primase activity
C11O2_RS03170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C11O2_RS03175	COG2151	metal-sulfur cluster biosynthetic enzyme
C11O2_RS03220	COG1216	Glycosyl transferase, family 2
C11O2_RS03280	COG1368	sulfuric ester hydrolase activity
C11O2_RS03285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C11O2_RS03305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C11O2_RS03310	COG0285	dihydrofolate synthase activity
C11O2_RS03320	COG1104	cysteine desulfurase activity
C11O2_RS03345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C11O2_RS03350	COG0583	DNA-binding transcription factor activity
C11O2_RS03360	COG0564	pseudouridine synthase activity
C11O2_RS03390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C11O2_RS03395	COG1136	(ABC) transporter
C11O2_RS03400	COG0577	efflux transmembrane transporter activity
C11O2_RS03405	COG0584	glycerophosphoryl diester phosphodiesterase
C11O2_RS03415	COG1837	Belongs to the UPF0109 family
C11O2_RS03465	COG1349	DNA-binding transcription factor activity
C11O2_RS03470	COG1105	Belongs to the carbohydrate kinase PfkB family
C11O2_RS03475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C11O2_RS03475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C11O2_RS03475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C11O2_RS03480	COG1705	Flagellar rod assembly protein muramidase FlgJ
C11O2_RS03480	COG1388	LysM domain
C11O2_RS03485	COG1705	Flagellar rod assembly protein muramidase FlgJ
C11O2_RS03485	COG1388	LysM domain
C11O2_RS03505	COG0105	UTP biosynthetic process
C11O2_RS03525	COG0488	(ABC) transporter
C11O2_RS03535	COG0242	peptide deformylase activity
C11O2_RS03540	COG0737	Belongs to the 5'-nucleotidase family
C11O2_RS03545	COG2357	RelA SpoT domain protein
C11O2_RS03550	COG0745	RESPONSE REGULATOR receiver
C11O2_RS03585	COG3425	synthase
C11O2_RS03595	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C11O2_RS03655	COG0583	DNA-binding transcription factor activity
C11O2_RS03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C11O2_RS03685	COG0765	amino acid transport
C11O2_RS03705	COG0187	DNA topoisomerase II activity
C11O2_RS03715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C11O2_RS03735	COG0539	negative regulation of cytoplasmic translation
C11O2_RS03780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C11O2_RS03785	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C11O2_RS03795	COG0300	oxidoreductase activity
C11O2_RS03800	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C11O2_RS03800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C11O2_RS03815	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C11O2_RS03820	COG2384	SAM-dependent methyltransferase
C11O2_RS03830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C11O2_RS03835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C11O2_RS03845	COG1088	dTDP-glucose 4,6-dehydratase activity
C11O2_RS03850	COG1051	belongs to the nudix hydrolase family
C11O2_RS03855	COG0628	permease
C11O2_RS03860	COG0457	Tetratricopeptide repeat
C11O2_RS03865	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C11O2_RS03885	COG1129	ABC transporter
C11O2_RS03905	COG0488	(ABC) transporter
C11O2_RS03910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C11O2_RS03915	COG0022	dehydrogenase e1 component
C11O2_RS03915	COG0508	dehydrogenase complex catalyzes the overall conversion of
C11O2_RS03945	COG5492	domain, Protein
C11O2_RS03950	COG0095	Lipoate-protein ligase
C11O2_RS03955	COG3442	glutamine amidotransferase
C11O2_RS03960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C11O2_RS03965	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C11O2_RS03985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C11O2_RS03995	COG0647	UMP catabolic process
C11O2_RS04015	COG1518	maintenance of DNA repeat elements
C11O2_RS04020	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C11O2_RS04035	COG0105	UTP biosynthetic process
C11O2_RS04070	COG3715	PTS system
C11O2_RS04075	COG3716	PTS system mannose fructose sorbose family IID component
C11O2_RS04080	COG2972	Histidine kinase
C11O2_RS04085	COG2207	Transcriptional regulator
C11O2_RS04085	COG4753	response regulator
C11O2_RS04090	COG1840	ABC-type Fe3 transport system, periplasmic component
C11O2_RS04105	COG1011	Hydrolase
C11O2_RS04110	COG1012	belongs to the aldehyde dehydrogenase family
C11O2_RS04125	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C11O2_RS04190	COG1131	(ABC) transporter
C11O2_RS04205	COG1396	sequence-specific DNA binding
C11O2_RS04235	COG0285	dihydrofolate synthase activity
C11O2_RS04255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C11O2_RS04270	COG1176	ABC-type spermidine putrescine transport system, permease component I
C11O2_RS04275	COG1177	transmembrane transport
C11O2_RS04285	COG4565	transcriptional regulatory protein
C11O2_RS04290	COG3290	protein histidine kinase activity
C11O2_RS04295	COG3493	citrate carrier protein
C11O2_RS04310	COG3700	Belongs to the class B bacterial acid phosphatase family
C11O2_RS04315	COG0038	chloride channel
C11O2_RS04325	COG0628	permease
C11O2_RS04335	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C11O2_RS04350	COG1104	cysteine desulfurase activity
C11O2_RS04365	COG2357	RelA SpoT domain protein
C11O2_RS04375	COG0564	pseudouridine synthase activity
C11O2_RS04380	COG0280	phosphate acetyltransferase
C11O2_RS04400	COG1174	glycine betaine transport
C11O2_RS04420	COG2233	PERMEase
C11O2_RS04445	COG2890	protein-(glutamine-N5) methyltransferase activity
C11O2_RS04475	COG1132	(ABC) transporter
C11O2_RS04480	COG1132	(ABC) transporter
C11O2_RS04500	COG3764	Sortase (surface protein transpeptidase)
C11O2_RS04505	COG0346	lactoylglutathione lyase activity
C11O2_RS04525	COG1272	protein, Hemolysin III
C11O2_RS04545	COG0758	DNA mediated transformation
C11O2_RS04550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C11O2_RS04600	COG0511	ligase activity, forming carbon-carbon bonds
C11O2_RS04605	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C11O2_RS04620	COG2851	Citrate transporter
C11O2_RS04630	COG0511	ligase activity, forming carbon-carbon bonds
C11O2_RS04635	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C11O2_RS04665	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C11O2_RS04685	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C11O2_RS04695	COG2188	Transcriptional regulator
C11O2_RS04715	COG0488	(ABC) transporter
C11O2_RS04725	COG0352	thiamine-phosphate diphosphorylase activity
C11O2_RS04725	COG0351	phosphomethylpyrimidine kinase
C11O2_RS04730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C11O2_RS04740	COG1328	CTP reductase activity
C11O2_RS04740	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C11O2_RS04745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C11O2_RS04775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C11O2_RS04795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C11O2_RS04800	COG4684	Psort location CytoplasmicMembrane, score
C11O2_RS04805	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C11O2_RS04810	COG1079	Belongs to the binding-protein-dependent transport system permease family
C11O2_RS04815	COG4603	Belongs to the binding-protein-dependent transport system permease family
C11O2_RS04820	COG3845	ABC transporter
C11O2_RS04825	COG1744	ABC transporter substrate-binding protein PnrA-like
C11O2_RS04830	COG0295	cytidine deaminase activity
C11O2_RS04835	COG2813	Specifically methylates the guanine in position
C11O2_RS04850	COG5002	protein histidine kinase activity
C11O2_RS04855	COG0745	RESPONSE REGULATOR receiver
C11O2_RS04870	COG0704	Plays a role in the regulation of phosphate uptake
C11O2_RS04885	COG0581	inorganic phosphate transmembrane transporter activity
C11O2_RS04890	COG0573	inorganic phosphate transmembrane transporter activity
C11O2_RS04900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C11O2_RS04900	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C11O2_RS04905	COG0483	inositol monophosphate 1-phosphatase activity
C11O2_RS04920	COG0196	riboflavin kinase activity
C11O2_RS04950	COG4591	ABC-type transport system involved in lipoprotein release permease component
C11O2_RS04950	COG1136	(ABC) transporter
C11O2_RS05000	COG1115	amino acid carrier protein
C11O2_RS05005	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C11O2_RS05015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C11O2_RS05020	COG1126	abc transporter atp-binding protein
C11O2_RS05025	COG0765	amino acid transport
C11O2_RS05030	COG2824	Alkylphosphonate utilization operon protein PhnA
C11O2_RS05045	COG0469	pyruvate kinase activity
C11O2_RS05060	COG1725	Transcriptional regulator
C11O2_RS05065	COG1131	(ABC) transporter
C11O2_RS05125	COG1396	sequence-specific DNA binding
C11O2_RS05170	COG0058	SHG alpha-glucan phosphorylase activity
C11O2_RS05175	COG1640	4-alpha-glucanotransferase
C11O2_RS05180	COG1609	Transcriptional regulator
C11O2_RS05185	COG2182	Extracellular solute-binding protein
C11O2_RS05190	COG1175	transmembrane transport
C11O2_RS05195	COG3833	ABC-type maltose transport systems, permease component
C11O2_RS05210	COG3833	ABC-type maltose transport systems, permease component
C11O2_RS05215	COG1175	transmembrane transport
C11O2_RS05225	COG0366	Alpha amylase catalytic
C11O2_RS05230	COG2182	Extracellular solute-binding protein
C11O2_RS05240	COG0657	acetylesterase activity
C11O2_RS05245	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C11O2_RS05255	COG1696	Membrane protein involved in D-alanine export
C11O2_RS05275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C11O2_RS05280	COG1126	abc transporter atp-binding protein
C11O2_RS05285	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C11O2_RS05295	COG1447	Phosphotransferase system cellobiose-specific component IIA
C11O2_RS05305	COG3711	transcriptional antiterminator
C11O2_RS05305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C11O2_RS05315	COG2723	6-phospho-beta-galactosidase activity
C11O2_RS05345	COG1187	pseudouridine synthase activity
C11O2_RS05355	COG2814	Major facilitator Superfamily
C11O2_RS05405	COG4109	DRTGG domain
C11O2_RS05410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C11O2_RS05435	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C11O2_RS05435	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C11O2_RS05445	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C11O2_RS05450	COG1956	GAF domain-containing protein
C11O2_RS05470	COG0513	Belongs to the DEAD box helicase family
C11O2_RS05475	COG0726	polysaccharide deacetylase
C11O2_RS05495	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C11O2_RS05500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C11O2_RS05505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C11O2_RS05535	COG1476	TRANSCRIPTIONal
C11O2_RS05550	COG4122	O-methyltransferase activity
C11O2_RS05555	COG2223	nitrite transmembrane transporter activity
C11O2_RS05570	COG1187	pseudouridine synthase activity
C11O2_RS05615	COG2333	competence protein COMEC
C11O2_RS05615	COG0658	competence protein
C11O2_RS05700	COG0740	serine-type endopeptidase activity
C11O2_RS05705	COG4695	Portal protein
C11O2_RS05730	COG0270	DNA (cytosine-5-)-methyltransferase activity
C11O2_RS05750	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C11O2_RS05800	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C11O2_RS05800	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C11O2_RS05840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C11O2_RS05855	COG0488	(ABC) transporter
C11O2_RS05890	COG1555	photosystem II stabilization
C11O2_RS05890	COG1596	polysaccharide export
C11O2_RS05895	COG0204	Acyl-transferase
C11O2_RS05900	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C11O2_RS05915	COG0513	Belongs to the DEAD box helicase family
C11O2_RS05935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C11O2_RS05950	COG0768	penicillin binding
C11O2_RS05955	COG2116	formate transmembrane transporter activity
C11O2_RS05965	COG1827	regulation of RNA biosynthetic process
C11O2_RS05980	COG2217	Heavy metal translocating P-type atpase
C11O2_RS06095	COG3561	AntA/AntB antirepressor
C11O2_RS06110	COG1396	sequence-specific DNA binding
C11O2_RS06125	COG0582	viral genome integration into host DNA
C11O2_RS06140	COG2755	lipolytic protein G-D-S-L family
C11O2_RS06155	COG0497	DNA recombination
C11O2_RS06160	COG1438	arginine binding
C11O2_RS06165	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C11O2_RS06190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C11O2_RS06195	COG0415	Belongs to the DNA photolyase family
C11O2_RS06205	COG0765	amino acid transport
C11O2_RS06210	COG4703	Protein of unknown function (DUF1797)
C11O2_RS06215	COG0542	response to heat
C11O2_RS06220	COG0494	nUDIX hydrolase
C11O2_RS06235	COG3599	regulation of cell shape
C11O2_RS06240	COG2302	S4 RNA-binding domain
C11O2_RS06255	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C11O2_RS06290	COG1217	gtp-binding protein TYPA
C11O2_RS06295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C11O2_RS06300	COG1940	carbohydrate kinase activity
C11O2_RS06310	COG0783	Belongs to the Dps family
C11O2_RS06325	COG4470	Protein conserved in bacteria
C11O2_RS06335	COG3480	Lon protease (S16) C-terminal proteolytic domain
C11O2_RS06345	COG0742	ribosomal rna small subunit methyltransferase
C11O2_RS06355	COG0549	Belongs to the carbamate kinase family
C11O2_RS06360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C11O2_RS06365	COG1288	antiporter activity
C11O2_RS06380	COG2235	arginine
C11O2_RS06405	COG2972	Histidine kinase
C11O2_RS06420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C11O2_RS06425	COG0785	Cytochrome C biogenesis protein
C11O2_RS06430	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C11O2_RS06435	COG1518	maintenance of DNA repeat elements
C11O2_RS06500	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C11O2_RS06500	COG1605	Chorismate mutase
C11O2_RS06520	COG2226	methyltransferase
C11O2_RS06530	COG3250	beta-galactosidase activity
C11O2_RS06535	COG2207	Transcriptional regulator
C11O2_RS06535	COG4753	response regulator
C11O2_RS06540	COG2972	Histidine kinase
C11O2_RS06550	COG1653	transport
C11O2_RS06555	COG0395	ABC-type sugar transport system, permease component
C11O2_RS06560	COG1175	transmembrane transport
C11O2_RS06565	COG1940	carbohydrate kinase activity
C11O2_RS06570	COG2723	6-phospho-beta-galactosidase activity
C11O2_RS06575	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C11O2_RS06590	COG0383	alpha-mannosidase activity
C11O2_RS06695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C11O2_RS06700	COG1739	Uncharacterized protein family UPF0029
C11O2_RS06710	COG1098	S1 RNA binding domain
C11O2_RS06720	COG2197	response regulator
C11O2_RS06725	COG4585	Histidine kinase
C11O2_RS06735	COG2815	serine threonine protein kinase
C11O2_RS06735	COG0515	serine threonine protein kinase
C11O2_RS06745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C11O2_RS06745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C11O2_RS06755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C11O2_RS06780	COG0183	Belongs to the thiolase family
C11O2_RS06785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C11O2_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
C11O2_RS06800	COG2610	gluconate transmembrane transporter activity
C11O2_RS06815	COG0116	Belongs to the methyltransferase superfamily
C11O2_RS06840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C11O2_RS06845	COG3579	cysteine-type endopeptidase activity
C11O2_RS06855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C11O2_RS06860	COG1113	amino acid transport
C11O2_RS06865	COG0492	ferredoxin-NADP+ reductase activity
C11O2_RS06875	COG1126	abc transporter atp-binding protein
C11O2_RS06885	COG0513	Belongs to the DEAD box helicase family
C11O2_RS06895	COG0768	penicillin binding
C11O2_RS06935	COG1131	(ABC) transporter
C11O2_RS06960	COG0446	pyridine nucleotide-disulphide oxidoreductase
C11O2_RS06965	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C11O2_RS07005	COG1755	Isoprenylcysteine carboxyl methyltransferase
C11O2_RS07010	COG0656	L-ascorbic acid biosynthetic process
C11O2_RS07020	COG1283	sodium-dependent phosphate transmembrane transporter activity
C11O2_RS07040	COG0561	phosphatase activity
C11O2_RS07045	COG2860	membrane
C11O2_RS07100	COG2217	Heavy metal translocating P-type atpase
C11O2_RS07130	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C11O2_RS07135	COG0195	Participates in both transcription termination and antitermination
C11O2_RS07160	COG4473	ABC transporter
C11O2_RS07165	COG1131	(ABC) transporter
C11O2_RS07170	COG0537	adenosine 5'-monophosphoramidase activity
C11O2_RS07180	COG1316	TRANSCRIPTIONal
C11O2_RS07190	COG0802	atpase or kinase
C11O2_RS07195	COG2252	PERMEase
C11O2_RS07200	COG0561	phosphatase activity
C11O2_RS07210	COG3715	PTS system
C11O2_RS07215	COG3716	PTS system mannose fructose sorbose family IID component
C11O2_RS07240	COG0439	Biotin carboxylase
C11O2_RS07255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C11O2_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
C11O2_RS07265	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C11O2_RS07290	COG1024	Enoyl-CoA hydratase
C11O2_RS07325	COG0588	phosphoglycerate mutase activity
C11O2_RS07330	COG2261	transglycosylase associated protein
C11O2_RS07365	COG1335	isochorismatase
C11O2_RS07375	COG0436	Aminotransferase
C11O2_RS07385	COG0561	phosphatase activity
C11O2_RS07390	COG0252	asparaginase activity
C11O2_RS07405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C11O2_RS07415	COG1129	ABC transporter
C11O2_RS07430	COG1132	(ABC) transporter
C11O2_RS07435	COG4988	ABC transporter
C11O2_RS07440	COG1120	ATPase activity
C11O2_RS07465	COG3942	CHAP domain
C11O2_RS07465	COG1388	LysM domain
C11O2_RS07495	COG1482	cell wall glycoprotein biosynthetic process
C11O2_RS07500	COG1940	carbohydrate kinase activity
C11O2_RS07510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C11O2_RS07510	COG1263	PTS System
C11O2_RS07510	COG2190	(PTS) system
C11O2_RS07515	COG1621	beta-fructofuranosidase activity
C11O2_RS07520	COG1609	Transcriptional regulator
C11O2_RS07540	COG2131	deaminase
C11O2_RS07545	COG0006	proline dipeptidase activity
C11O2_RS07585	COG1194	a g-specific adenine glycosylase
C11O2_RS07595	COG3118	belongs to the thioredoxin family
C11O2_RS07625	COG0681	Belongs to the peptidase S26 family
C11O2_RS07630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C11O2_RS07645	COG1882	Formate acetyltransferase
C11O2_RS07650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C11O2_RS07665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C11O2_RS07675	COG2814	Major facilitator Superfamily
C11O2_RS07680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C11O2_RS07705	COG0789	Transcriptional regulator
C11O2_RS07720	COG2081	HI0933 family
C11O2_RS07730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C11O2_RS07735	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C11O2_RS07755	COG0456	acetyltransferase
C11O2_RS07760	COG1214	PFAM Peptidase M22, glycoprotease
C11O2_RS07775	COG0174	glutamine synthetase
C11O2_RS07780	COG0789	Transcriptional regulator
C11O2_RS07795	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C11O2_RS07860	COG0668	transmembrane transport
C11O2_RS07870	COG4720	Psort location CytoplasmicMembrane, score
C11O2_RS07875	COG0351	phosphomethylpyrimidine kinase
C11O2_RS07920	COG2801	Transposase and inactivated derivatives
C11O2_RS07930	COG0444	Belongs to the ABC transporter superfamily
C11O2_RS07935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C11O2_RS07940	COG0601	transmembrane transport
C11O2_RS07945	COG4166	transmembrane transport
C11O2_RS07950	COG1686	Belongs to the peptidase S11 family
C11O2_RS07955	COG1686	Belongs to the peptidase S11 family
C11O2_RS07970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C11O2_RS07975	COG0719	Fe-S assembly protein
C11O2_RS07985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C11O2_RS08005	COG0765	amino acid transport
C11O2_RS08045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C11O2_RS08060	COG1564	THIamine pyrophosphokinase
C11O2_RS08085	COG0084	hydrolase, TatD family'
C11O2_RS08100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C11O2_RS08110	COG0395	ABC-type sugar transport system, permease component
C11O2_RS08115	COG1175	transmembrane transport
C11O2_RS08135	COG1847	R3H domain protein
C11O2_RS08160	COG3290	protein histidine kinase activity
C11O2_RS08185	COG0756	dUTP diphosphatase activity
C11O2_RS08195	COG1132	(ABC) transporter
C11O2_RS08200	COG1132	(ABC) transporter
C11O2_RS08220	COG0457	Tetratricopeptide repeat
C11O2_RS08220	COG0705	Rhomboid family
C11O2_RS08260	COG3711	transcriptional antiterminator
C11O2_RS08275	COG1705	Flagellar rod assembly protein muramidase FlgJ
C11O2_RS08275	COG3942	CHAP domain
C11O2_RS08280	COG2205	protein histidine kinase activity
C11O2_RS08285	COG0745	RESPONSE REGULATOR receiver
C11O2_RS08290	COG0577	efflux transmembrane transporter activity
C11O2_RS08295	COG1136	(ABC) transporter
C11O2_RS08360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C11O2_RS08375	COG1882	Formate acetyltransferase
C11O2_RS08380	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C11O2_RS08385	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C11O2_RS08390	COG1447	Phosphotransferase system cellobiose-specific component IIA
C11O2_RS08395	COG2390	Transcriptional regulator
C11O2_RS08400	COG1349	DNA-binding transcription factor activity
C11O2_RS08405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C11O2_RS08425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C11O2_RS08440	COG0564	pseudouridine synthase activity
C11O2_RS08475	COG0542	response to heat
C11O2_RS08480	COG4463	regulation of RNA biosynthetic process
C11O2_RS08495	COG0450	alkyl hydroperoxide reductase
C11O2_RS08510	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C11O2_RS08520	COG3404	Formiminotransferase-cyclodeaminase
C11O2_RS08535	COG0531	amino acid
C11O2_RS08565	COG3590	peptidase
C11O2_RS08570	COG0366	Alpha amylase catalytic
C11O2_RS08575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C11O2_RS08575	COG1263	PTS System
C11O2_RS08580	COG2188	Transcriptional regulator
C11O2_RS08590	COG1733	regulation of RNA biosynthetic process
C11O2_RS08595	COG2514	catechol 2,3-dioxygenase activity
C11O2_RS08605	COG0602	queuosine metabolic process
C11O2_RS08620	COG1328	CTP reductase activity
C11O2_RS08645	COG1393	Belongs to the ArsC family
C11O2_RS08660	COG0519	Catalyzes the synthesis of GMP from XMP
C11O2_RS08670	COG2814	Major facilitator Superfamily
C11O2_RS08705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C11O2_RS08710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C11O2_RS08715	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C11O2_RS08800	COG1511	domain protein
C11O2_RS08820	COG5433	transposase activity
C11O2_RS08830	COG0305	Participates in initiation and elongation during chromosome replication
C11O2_RS08860	COG1760	l-serine dehydratase
C11O2_RS08865	COG1760	l-serine dehydratase
C11O2_RS08870	COG0741	lytic transglycosylase activity
C11O2_RS08875	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C11O2_RS08890	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C11O2_RS08900	COG0612	Peptidase, M16
C11O2_RS08910	COG1215	transferase activity, transferring glycosyl groups
C11O2_RS08940	COG0517	IMP dehydrogenase activity
C11O2_RS08940	COG0516	GMP reductase activity
C11O2_RS08950	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C11O2_RS08955	COG0488	(ABC) transporter
C11O2_RS08995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C11O2_RS09000	COG1475	DNA binding