locus-tag	class	description
C7K40_RS00010	COG0592	DNA-directed DNA polymerase activity
C7K40_RS00020	COG0012	GTP binding
C7K40_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7K40_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7K40_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7K40_RS00065	COG0531	amino acid
C7K40_RS00245	COG3942	CHAP domain
C7K40_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7K40_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7K40_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7K40_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7K40_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7K40_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7K40_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
C7K40_RS00355	COG1454	alcohol dehydrogenase
C7K40_RS00360	COG1064	alcohol dehydrogenase
C7K40_RS00365	COG0534	Mate efflux family protein
C7K40_RS00480	COG0201	protein transport
C7K40_RS00630	COG1121	(ABC) transporter
C7K40_RS00635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7K40_RS00650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K40_RS00670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7K40_RS00675	COG1459	type II secretion system
C7K40_RS00680	COG4537	Required for transformation and DNA binding
C7K40_RS00720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7K40_RS00725	COG1363	Peptidase, m42
C7K40_RS00745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7K40_RS00750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7K40_RS00765	COG1428	Deoxynucleoside kinase
C7K40_RS00770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7K40_RS00800	COG4509	Sortase family
C7K40_RS00830	COG2031	fatty acid transporter
C7K40_RS00845	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7K40_RS00860	COG0251	oxidation-reduction process
C7K40_RS00875	COG1269	ATP hydrolysis coupled proton transport
C7K40_RS00880	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7K40_RS00890	COG1527	subunit (C
C7K40_RS00895	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
C7K40_RS00930	COG1744	ABC transporter substrate-binding protein PnrA-like
C7K40_RS00935	COG5433	transposase activity
C7K40_RS00990	COG0626	cystathionine gamma-synthase activity
C7K40_RS01020	COG3623	hexulose-6-phosphate isomerase
C7K40_RS01045	COG4175	Glycine betaine
C7K40_RS01045	COG3448	diguanylate cyclase activity
C7K40_RS01055	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7K40_RS01055	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7K40_RS01075	COG3969	phosphoadenosine phosphosulfate
C7K40_RS01080	COG1475	DNA binding
C7K40_RS01105	COG0157	Belongs to the NadC ModD family
C7K40_RS01130	COG1268	BioY protein
C7K40_RS01135	COG1234	tRNA 3'-trailer cleavage
C7K40_RS01170	COG0457	Tetratricopeptide repeat
C7K40_RS01170	COG0705	Rhomboid family
C7K40_RS01190	COG5433	transposase activity
C7K40_RS01200	COG1132	(ABC) transporter
C7K40_RS01205	COG1132	(ABC) transporter
C7K40_RS01215	COG0756	dUTP diphosphatase activity
C7K40_RS01240	COG3290	protein histidine kinase activity
C7K40_RS01265	COG1847	R3H domain protein
C7K40_RS01285	COG1175	transmembrane transport
C7K40_RS01290	COG0395	ABC-type sugar transport system, permease component
C7K40_RS01300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7K40_RS01315	COG0084	hydrolase, TatD family'
C7K40_RS01340	COG1564	THIamine pyrophosphokinase
C7K40_RS01360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7K40_RS01400	COG0765	amino acid transport
C7K40_RS01420	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7K40_RS01430	COG0719	Fe-S assembly protein
C7K40_RS01435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7K40_RS01450	COG1686	Belongs to the peptidase S11 family
C7K40_RS01455	COG1686	Belongs to the peptidase S11 family
C7K40_RS01460	COG4166	transmembrane transport
C7K40_RS01465	COG0601	transmembrane transport
C7K40_RS01470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7K40_RS01475	COG0444	Belongs to the ABC transporter superfamily
C7K40_RS01485	COG2801	Transposase and inactivated derivatives
C7K40_RS01530	COG0351	phosphomethylpyrimidine kinase
C7K40_RS01535	COG4720	Psort location CytoplasmicMembrane, score
C7K40_RS01545	COG0668	transmembrane transport
C7K40_RS01605	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
C7K40_RS01620	COG0789	Transcriptional regulator
C7K40_RS01625	COG0174	glutamine synthetase
C7K40_RS01640	COG1214	PFAM Peptidase M22, glycoprotease
C7K40_RS01645	COG0456	acetyltransferase
C7K40_RS01665	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C7K40_RS01670	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7K40_RS01680	COG2081	HI0933 family
C7K40_RS01715	COG0789	Transcriptional regulator
C7K40_RS01740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7K40_RS01745	COG2814	Major facilitator Superfamily
C7K40_RS01755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7K40_RS01770	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7K40_RS01775	COG1882	Formate acetyltransferase
C7K40_RS01790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7K40_RS01795	COG0681	Belongs to the peptidase S26 family
C7K40_RS01825	COG3118	belongs to the thioredoxin family
C7K40_RS01835	COG1194	a g-specific adenine glycosylase
C7K40_RS01885	COG1396	sequence-specific DNA binding
C7K40_RS01900	COG3561	AntA/AntB antirepressor
C7K40_RS01935	COG3935	DnaD domain protein
C7K40_RS01960	COG3723	Recombinational DNA repair protein, rece pathway
C7K40_RS02005	COG1475	DNA binding
C7K40_RS02130	COG1388	LysM domain
C7K40_RS02130	COG0860	N-Acetylmuramoyl-L-alanine amidase
C7K40_RS02165	COG0006	proline dipeptidase activity
C7K40_RS02170	COG2131	deaminase
C7K40_RS02190	COG1609	Transcriptional regulator
C7K40_RS02195	COG1621	beta-fructofuranosidase activity
C7K40_RS02200	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K40_RS02200	COG1263	PTS System
C7K40_RS02200	COG2190	(PTS) system
C7K40_RS02210	COG1940	carbohydrate kinase activity
C7K40_RS02215	COG1482	cell wall glycoprotein biosynthetic process
C7K40_RS02240	COG1388	LysM domain
C7K40_RS02240	COG3942	CHAP domain
C7K40_RS02265	COG1120	ATPase activity
C7K40_RS02270	COG4988	ABC transporter
C7K40_RS02275	COG1132	(ABC) transporter
C7K40_RS02290	COG1129	ABC transporter
C7K40_RS02300	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7K40_RS02315	COG0252	asparaginase activity
C7K40_RS02320	COG0561	phosphatase activity
C7K40_RS02330	COG0436	Aminotransferase
C7K40_RS02340	COG1335	isochorismatase
C7K40_RS02375	COG2261	transglycosylase associated protein
C7K40_RS02380	COG0588	phosphoglycerate mutase activity
C7K40_RS02415	COG1024	Enoyl-CoA hydratase
C7K40_RS02440	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7K40_RS02445	COG1028	Short-chain dehydrogenase reductase Sdr
C7K40_RS02450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7K40_RS02465	COG0439	Biotin carboxylase
C7K40_RS02490	COG3716	PTS system mannose fructose sorbose family IID component
C7K40_RS02495	COG3715	PTS system
C7K40_RS02505	COG0561	phosphatase activity
C7K40_RS02510	COG2252	PERMEase
C7K40_RS02515	COG0802	atpase or kinase
C7K40_RS02525	COG1316	TRANSCRIPTIONal
C7K40_RS02535	COG0537	adenosine 5'-monophosphoramidase activity
C7K40_RS02540	COG1131	(ABC) transporter
C7K40_RS02545	COG4473	ABC transporter
C7K40_RS02570	COG0195	Participates in both transcription termination and antitermination
C7K40_RS02575	COG2740	Nucleic-acid-binding protein implicated in transcription termination
C7K40_RS02605	COG2217	Heavy metal translocating P-type atpase
C7K40_RS02625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K40_RS02665	COG2860	membrane
C7K40_RS02670	COG0561	phosphatase activity
C7K40_RS02690	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7K40_RS02700	COG0656	L-ascorbic acid biosynthetic process
C7K40_RS02705	COG1755	Isoprenylcysteine carboxyl methyltransferase
C7K40_RS02745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7K40_RS02750	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7K40_RS02775	COG1131	(ABC) transporter
C7K40_RS02810	COG0826	peptidase U32
C7K40_RS02815	COG4443	Transcriptional Coactivator p15 (PC4)
C7K40_RS02860	COG0386	Belongs to the glutathione peroxidase family
C7K40_RS02865	COG1164	Oligoendopeptidase f
C7K40_RS02875	COG0772	Belongs to the SEDS family
C7K40_RS02910	COG1078	dGTPase activity
C7K40_RS02925	COG1609	Transcriptional regulator
C7K40_RS02935	COG3716	PTS system mannose fructose sorbose family IID component
C7K40_RS02940	COG3715	PTS system
C7K40_RS02945	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K40_RS02960	COG1028	Short-chain dehydrogenase reductase Sdr
C7K40_RS02980	COG0546	phosphoglycolate phosphatase activity
C7K40_RS02990	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7K40_RS03000	COG2884	Cell division ATP-binding protein ftsE
C7K40_RS03005	COG2177	Part of the ABC transporter FtsEX involved in
C7K40_RS03020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7K40_RS03020	COG1199	ATP-dependent helicase activity
C7K40_RS03025	COG0436	Aminotransferase
C7K40_RS03060	COG2188	Transcriptional regulator
C7K40_RS03065	COG2222	sugar isomerase
C7K40_RS03075	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7K40_RS03080	COG0716	FMN binding
C7K40_RS03090	COG0038	chloride channel
C7K40_RS03180	COG1131	(ABC) transporter
C7K40_RS03205	COG4708	membrane
C7K40_RS03215	COG1597	lipid kinase activity
C7K40_RS03300	COG0577	efflux transmembrane transporter activity
C7K40_RS03310	COG2321	neutral zinc metallopeptidase
C7K40_RS03325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K40_RS03335	COG1970	mechanosensitive ion channel activity
C7K40_RS03340	COG0358	DNA primase activity
C7K40_RS03345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7K40_RS03350	COG2151	metal-sulfur cluster biosynthetic enzyme
C7K40_RS03395	COG1216	Glycosyl transferase, family 2
C7K40_RS03455	COG1368	sulfuric ester hydrolase activity
C7K40_RS03460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7K40_RS03480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7K40_RS03485	COG0285	dihydrofolate synthase activity
C7K40_RS03495	COG1104	cysteine desulfurase activity
C7K40_RS03520	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7K40_RS03530	COG0583	DNA-binding transcription factor activity
C7K40_RS03540	COG0564	pseudouridine synthase activity
C7K40_RS03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7K40_RS03585	COG1136	(ABC) transporter
C7K40_RS03590	COG0577	efflux transmembrane transporter activity
C7K40_RS03595	COG0584	glycerophosphoryl diester phosphodiesterase
C7K40_RS03605	COG1837	Belongs to the UPF0109 family
C7K40_RS03655	COG1349	DNA-binding transcription factor activity
C7K40_RS03660	COG1105	Belongs to the carbohydrate kinase PfkB family
C7K40_RS03665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K40_RS03665	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K40_RS03665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7K40_RS03670	COG1388	LysM domain
C7K40_RS03670	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K40_RS03675	COG1388	LysM domain
C7K40_RS03675	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K40_RS03695	COG0105	UTP biosynthetic process
C7K40_RS03715	COG0488	(ABC) transporter
C7K40_RS03725	COG0242	peptide deformylase activity
C7K40_RS03735	COG2357	RelA SpoT domain protein
C7K40_RS03740	COG0745	RESPONSE REGULATOR receiver
C7K40_RS03775	COG3425	synthase
C7K40_RS03785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7K40_RS03845	COG0583	DNA-binding transcription factor activity
C7K40_RS03870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K40_RS03875	COG0765	amino acid transport
C7K40_RS03895	COG0187	DNA topoisomerase II activity
C7K40_RS03905	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7K40_RS03925	COG0539	negative regulation of cytoplasmic translation
C7K40_RS03970	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7K40_RS03975	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
C7K40_RS03985	COG0300	oxidoreductase activity
C7K40_RS03990	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7K40_RS03990	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
C7K40_RS04005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7K40_RS04010	COG2384	SAM-dependent methyltransferase
C7K40_RS04020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7K40_RS04025	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C7K40_RS04035	COG1088	dTDP-glucose 4,6-dehydratase activity
C7K40_RS04040	COG1051	belongs to the nudix hydrolase family
C7K40_RS04045	COG0628	permease
C7K40_RS04050	COG0457	Tetratricopeptide repeat
C7K40_RS04055	COG1293	RNA-binding protein homologous to eukaryotic snRNP
C7K40_RS04075	COG1129	ABC transporter
C7K40_RS04095	COG0488	(ABC) transporter
C7K40_RS04100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7K40_RS04105	COG0022	dehydrogenase e1 component
C7K40_RS04105	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7K40_RS04110	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7K40_RS04130	COG5492	domain, Protein
C7K40_RS04135	COG0095	Lipoate-protein ligase
C7K40_RS04140	COG3442	glutamine amidotransferase
C7K40_RS04145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7K40_RS04150	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
C7K40_RS04170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7K40_RS04180	COG0647	UMP catabolic process
C7K40_RS04195	COG0105	UTP biosynthetic process
C7K40_RS04230	COG3715	PTS system
C7K40_RS04235	COG3716	PTS system mannose fructose sorbose family IID component
C7K40_RS04240	COG2972	Histidine kinase
C7K40_RS04245	COG4753	response regulator
C7K40_RS04245	COG2207	Transcriptional regulator
C7K40_RS04255	COG1012	belongs to the aldehyde dehydrogenase family
C7K40_RS04270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7K40_RS04345	COG1131	(ABC) transporter
C7K40_RS04390	COG0285	dihydrofolate synthase activity
C7K40_RS04425	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7K40_RS04430	COG1177	transmembrane transport
C7K40_RS04440	COG4565	transcriptional regulatory protein
C7K40_RS04450	COG3493	citrate carrier protein
C7K40_RS04465	COG3700	Belongs to the class B bacterial acid phosphatase family
C7K40_RS04470	COG0038	chloride channel
C7K40_RS04480	COG0628	permease
C7K40_RS04490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7K40_RS04505	COG1104	cysteine desulfurase activity
C7K40_RS04520	COG2357	RelA SpoT domain protein
C7K40_RS04530	COG0564	pseudouridine synthase activity
C7K40_RS04535	COG0280	phosphate acetyltransferase
C7K40_RS04540	COG4221	oxidoreductase activity
C7K40_RS04555	COG1174	glycine betaine transport
C7K40_RS04565	COG5433	transposase activity
C7K40_RS04580	COG2233	PERMEase
C7K40_RS04605	COG2890	protein-(glutamine-N5) methyltransferase activity
C7K40_RS04635	COG1132	(ABC) transporter
C7K40_RS04640	COG1132	(ABC) transporter
C7K40_RS04660	COG3764	Sortase (surface protein transpeptidase)
C7K40_RS04665	COG0346	lactoylglutathione lyase activity
C7K40_RS04680	COG1597	lipid kinase activity
C7K40_RS04685	COG1272	protein, Hemolysin III
C7K40_RS04705	COG0758	DNA mediated transformation
C7K40_RS04710	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7K40_RS04760	COG0511	ligase activity, forming carbon-carbon bonds
C7K40_RS04765	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7K40_RS04780	COG2851	Citrate transporter
C7K40_RS04790	COG0511	ligase activity, forming carbon-carbon bonds
C7K40_RS04795	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7K40_RS04825	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
C7K40_RS04845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7K40_RS04855	COG2188	Transcriptional regulator
C7K40_RS04875	COG0488	(ABC) transporter
C7K40_RS04885	COG0351	phosphomethylpyrimidine kinase
C7K40_RS04885	COG0352	thiamine-phosphate diphosphorylase activity
C7K40_RS04890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7K40_RS04900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7K40_RS04900	COG1328	CTP reductase activity
C7K40_RS04905	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7K40_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7K40_RS04955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7K40_RS04960	COG4684	Psort location CytoplasmicMembrane, score
C7K40_RS04965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7K40_RS04970	COG1079	Belongs to the binding-protein-dependent transport system permease family
C7K40_RS04975	COG4603	Belongs to the binding-protein-dependent transport system permease family
C7K40_RS04980	COG3845	ABC transporter
C7K40_RS04985	COG1744	ABC transporter substrate-binding protein PnrA-like
C7K40_RS04990	COG0295	cytidine deaminase activity
C7K40_RS04995	COG2813	Specifically methylates the guanine in position
C7K40_RS05010	COG5002	protein histidine kinase activity
C7K40_RS05015	COG0745	RESPONSE REGULATOR receiver
C7K40_RS05030	COG0704	Plays a role in the regulation of phosphate uptake
C7K40_RS05045	COG0581	inorganic phosphate transmembrane transporter activity
C7K40_RS05050	COG0573	inorganic phosphate transmembrane transporter activity
C7K40_RS05060	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7K40_RS05060	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7K40_RS05065	COG0483	inositol monophosphate 1-phosphatase activity
C7K40_RS05080	COG0196	riboflavin kinase activity
C7K40_RS05110	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7K40_RS05110	COG1136	(ABC) transporter
C7K40_RS05200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7K40_RS05210	COG0741	lytic transglycosylase activity
C7K40_RS05210	COG0791	NLP P60 protein
C7K40_RS05240	COG2946	Replication initiation factor
C7K40_RS05250	COG1674	ftsk spoiiie
C7K40_RS05270	COG1115	amino acid carrier protein
C7K40_RS05275	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C7K40_RS05285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K40_RS05290	COG1126	abc transporter atp-binding protein
C7K40_RS05295	COG0765	amino acid transport
C7K40_RS05300	COG2824	Alkylphosphonate utilization operon protein PhnA
C7K40_RS05315	COG0469	pyruvate kinase activity
C7K40_RS05330	COG1725	Transcriptional regulator
C7K40_RS05335	COG1131	(ABC) transporter
C7K40_RS05360	COG0058	SHG alpha-glucan phosphorylase activity
C7K40_RS05365	COG1640	4-alpha-glucanotransferase
C7K40_RS05370	COG1609	Transcriptional regulator
C7K40_RS05375	COG2182	Extracellular solute-binding protein
C7K40_RS05380	COG1175	transmembrane transport
C7K40_RS05385	COG3833	ABC-type maltose transport systems, permease component
C7K40_RS05400	COG3833	ABC-type maltose transport systems, permease component
C7K40_RS05405	COG1175	transmembrane transport
C7K40_RS05415	COG0366	Alpha amylase catalytic
C7K40_RS05420	COG2182	Extracellular solute-binding protein
C7K40_RS05430	COG0657	acetylesterase activity
C7K40_RS05435	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
C7K40_RS05445	COG1696	Membrane protein involved in D-alanine export
C7K40_RS05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K40_RS05470	COG1126	abc transporter atp-binding protein
C7K40_RS05475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K40_RS05485	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7K40_RS05495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7K40_RS05495	COG3711	transcriptional antiterminator
C7K40_RS05505	COG2723	6-phospho-beta-galactosidase activity
C7K40_RS05535	COG0157	Belongs to the NadC ModD family
C7K40_RS05550	COG2801	Transposase and inactivated derivatives
C7K40_RS05555	COG2801	Transposase and inactivated derivatives
C7K40_RS05560	COG2801	Transposase and inactivated derivatives
C7K40_RS05565	COG1187	pseudouridine synthase activity
C7K40_RS05575	COG2814	Major facilitator Superfamily
C7K40_RS05635	COG3843	relaxase mobilization nuclease domain protein
C7K40_RS05670	COG1131	(ABC) transporter
C7K40_RS05675	COG1309	transcriptional regulator
C7K40_RS05695	COG0551	DNA topoisomerase type I activity
C7K40_RS05695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7K40_RS05785	COG1484	DNA-dependent DNA replication
C7K40_RS05825	COG4109	DRTGG domain
C7K40_RS05830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7K40_RS05855	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
C7K40_RS05855	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
C7K40_RS05865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7K40_RS05870	COG1956	GAF domain-containing protein
C7K40_RS05890	COG0513	Belongs to the DEAD box helicase family
C7K40_RS05895	COG0726	polysaccharide deacetylase
C7K40_RS05915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7K40_RS05920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7K40_RS05925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7K40_RS05955	COG1476	TRANSCRIPTIONal
C7K40_RS05970	COG4122	O-methyltransferase activity
C7K40_RS05975	COG2223	nitrite transmembrane transporter activity
C7K40_RS05990	COG1187	pseudouridine synthase activity
C7K40_RS06035	COG2333	competence protein COMEC
C7K40_RS06035	COG0658	competence protein
C7K40_RS06040	COG1555	photosystem II stabilization
C7K40_RS06040	COG1596	polysaccharide export
C7K40_RS06045	COG0204	Acyl-transferase
C7K40_RS06050	COG2890	protein-(glutamine-N5) methyltransferase activity
C7K40_RS06065	COG0513	Belongs to the DEAD box helicase family
C7K40_RS06085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7K40_RS06100	COG0768	penicillin binding
C7K40_RS06105	COG2116	formate transmembrane transporter activity
C7K40_RS06115	COG1827	regulation of RNA biosynthetic process
C7K40_RS06130	COG2217	Heavy metal translocating P-type atpase
C7K40_RS06145	COG2755	lipolytic protein G-D-S-L family
C7K40_RS06160	COG0497	DNA recombination
C7K40_RS06165	COG1438	arginine binding
C7K40_RS06170	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
C7K40_RS06195	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7K40_RS06200	COG0415	Belongs to the DNA photolyase family
C7K40_RS06210	COG0765	amino acid transport
C7K40_RS06215	COG4703	Protein of unknown function (DUF1797)
C7K40_RS06220	COG0542	response to heat
C7K40_RS06225	COG0494	nUDIX hydrolase
C7K40_RS06240	COG3599	regulation of cell shape
C7K40_RS06245	COG2302	S4 RNA-binding domain
C7K40_RS06260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7K40_RS06295	COG1217	gtp-binding protein TYPA
C7K40_RS06300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7K40_RS06305	COG1940	carbohydrate kinase activity
C7K40_RS06315	COG0783	Belongs to the Dps family
C7K40_RS06330	COG4470	Protein conserved in bacteria
C7K40_RS06335	COG1609	Transcriptional regulator
C7K40_RS06340	COG3480	Lon protease (S16) C-terminal proteolytic domain
C7K40_RS06350	COG0742	ribosomal rna small subunit methyltransferase
C7K40_RS06360	COG0549	Belongs to the carbamate kinase family
C7K40_RS06365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7K40_RS06370	COG1288	antiporter activity
C7K40_RS06380	COG0454	-acetyltransferase
C7K40_RS06385	COG2235	arginine
C7K40_RS06410	COG2972	Histidine kinase
C7K40_RS06425	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7K40_RS06430	COG0785	Cytochrome C biogenesis protein
C7K40_RS06435	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
C7K40_RS06440	COG1518	maintenance of DNA repeat elements
C7K40_RS06505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
C7K40_RS06505	COG1605	Chorismate mutase
C7K40_RS06525	COG2226	methyltransferase
C7K40_RS06535	COG3250	beta-galactosidase activity
C7K40_RS06540	COG2207	Transcriptional regulator
C7K40_RS06540	COG4753	response regulator
C7K40_RS06545	COG2972	Histidine kinase
C7K40_RS06555	COG1653	transport
C7K40_RS06560	COG0395	ABC-type sugar transport system, permease component
C7K40_RS06565	COG1175	transmembrane transport
C7K40_RS06575	COG2723	6-phospho-beta-galactosidase activity
C7K40_RS06580	COG3525	Glycosyl hydrolase, family 20, catalytic domain
C7K40_RS06595	COG0383	alpha-mannosidase activity
C7K40_RS06695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
C7K40_RS06700	COG1739	Uncharacterized protein family UPF0029
C7K40_RS06710	COG1098	S1 RNA binding domain
C7K40_RS06720	COG2197	response regulator
C7K40_RS06725	COG4585	Histidine kinase
C7K40_RS06735	COG2815	serine threonine protein kinase
C7K40_RS06735	COG0515	serine threonine protein kinase
C7K40_RS06745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7K40_RS06745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7K40_RS06755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7K40_RS06775	COG0583	DNA-binding transcription factor activity
C7K40_RS06780	COG0183	Belongs to the thiolase family
C7K40_RS06785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7K40_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
C7K40_RS06800	COG2610	gluconate transmembrane transporter activity
C7K40_RS06815	COG0116	Belongs to the methyltransferase superfamily
C7K40_RS06840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K40_RS06845	COG3579	cysteine-type endopeptidase activity
C7K40_RS06855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7K40_RS06860	COG1113	amino acid transport
C7K40_RS06865	COG0492	ferredoxin-NADP+ reductase activity
C7K40_RS06875	COG1126	abc transporter atp-binding protein
C7K40_RS06885	COG0513	Belongs to the DEAD box helicase family
C7K40_RS06895	COG0768	penicillin binding
C7K40_RS06950	COG2183	response to ionizing radiation
C7K40_RS06960	COG0701	Predicted permease
C7K40_RS06965	COG3689	TIGRFAM TIGR03943 family protein
C7K40_RS06975	COG1263	PTS System
C7K40_RS06975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K40_RS06975	COG2190	(PTS) system
C7K40_RS06980	COG3711	transcriptional antiterminator
C7K40_RS06985	COG0477	Major facilitator Superfamily
C7K40_RS06990	COG0552	protein localization to endoplasmic reticulum
C7K40_RS06995	COG0561	phosphatase activity
C7K40_RS07000	COG0561	phosphatase activity
C7K40_RS07045	COG4695	Portal protein
C7K40_RS07130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7K40_RS07140	COG1196	nuclear chromosome segregation
C7K40_RS07150	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
C7K40_RS07155	COG5002	protein histidine kinase activity
C7K40_RS07160	COG0745	RESPONSE REGULATOR receiver
C7K40_RS07175	COG0183	Belongs to the thiolase family
C7K40_RS07185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7K40_RS07190	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7K40_RS07195	COG1461	Dihydroxyacetone kinase
C7K40_RS07200	COG2376	Dihydroxyacetone kinase
C7K40_RS07210	COG2376	Dihydroxyacetone kinase
C7K40_RS07225	COG4555	ABC transporter
C7K40_RS07235	COG0438	transferase activity, transferring glycosyl groups
C7K40_RS07245	COG1609	Transcriptional regulator
C7K40_RS07250	COG0006	proline dipeptidase activity
C7K40_RS07255	COG0778	Nitroreductase
C7K40_RS07265	COG0463	Glycosyl transferase, family 2
C7K40_RS07295	COG0557	exoribonuclease II activity
C7K40_RS07310	COG2814	Major facilitator Superfamily
C7K40_RS07315	COG0433	COG0433 Predicted ATPase
C7K40_RS07415	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7K40_RS07425	COG1573	uracil-dna glycosylase
C7K40_RS07430	COG1702	phosphate starvation-inducible protein PhoH
C7K40_RS07520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7K40_RS07530	COG0494	nUDIX hydrolase
C7K40_RS07545	COG0673	inositol 2-dehydrogenase activity
C7K40_RS07550	COG1028	Short-chain dehydrogenase reductase Sdr
C7K40_RS07660	COG1304	FMN binding
C7K40_RS07670	COG0708	Exodeoxyribonuclease III
C7K40_RS07675	COG1393	Belongs to the ArsC family
C7K40_RS07705	COG0470	DNA polymerase III
C7K40_RS07735	COG2244	polysaccharide biosynthetic process
C7K40_RS07745	COG1120	ATPase activity
C7K40_RS07750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7K40_RS07755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7K40_RS07760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7K40_RS07775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7K40_RS07780	COG1253	flavin adenine dinucleotide binding
C7K40_RS07785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
C7K40_RS07790	COG1242	4 iron, 4 sulfur cluster binding
C7K40_RS07795	COG0671	phosphoesterase, PA-phosphatase related
C7K40_RS07800	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
C7K40_RS07815	COG1187	pseudouridine synthase activity
C7K40_RS07870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7K40_RS07875	COG1254	Belongs to the acylphosphatase family
C7K40_RS07890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7K40_RS07910	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7K40_RS07920	COG1484	DNA-dependent DNA replication
C7K40_RS07940	COG0745	RESPONSE REGULATOR receiver
C7K40_RS07955	COG1704	LemA family
C7K40_RS07965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7K40_RS07970	COG0569	domain protein
C7K40_RS07980	COG1114	Component of the transport system for branched-chain amino acids
C7K40_RS07995	COG1464	Belongs to the NlpA lipoprotein family
C7K40_RS08000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7K40_RS08020	COG2226	methyltransferase
C7K40_RS08025	COG0799	negative regulation of ribosome biogenesis
C7K40_RS08030	COG1713	HD superfamily hydrolase involved in NAD metabolism
C7K40_RS08040	COG1534	Rna-binding protein
C7K40_RS08045	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7K40_RS08050	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
C7K40_RS08090	COG1929	Belongs to the glycerate kinase type-1 family
C7K40_RS08095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C7K40_RS08125	COG0577	efflux transmembrane transporter activity
C7K40_RS08130	COG1136	(ABC) transporter
C7K40_RS08155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K40_RS08155	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K40_RS08160	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7K40_RS08210	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7K40_RS08215	COG1476	TRANSCRIPTIONal
C7K40_RS08235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7K40_RS08245	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
C7K40_RS08265	COG1045	serine acetyltransferase
C7K40_RS08280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7K40_RS08295	COG3711	transcriptional antiterminator
C7K40_RS08325	COG1846	Transcriptional regulator
C7K40_RS08345	COG4589	Belongs to the CDS family
C7K40_RS08355	COG1862	Preprotein translocase
C7K40_RS08365	COG1523	belongs to the glycosyl hydrolase 13 family
C7K40_RS08380	COG3842	ATPase activity
C7K40_RS08420	COG1263	PTS System
C7K40_RS08420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K40_RS08420	COG2190	(PTS) system
C7K40_RS08425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7K40_RS08455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7K40_RS08460	COG0512	Glutamine amidotransferase of anthranilate synthase
C7K40_RS08465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7K40_RS08510	COG0601	transmembrane transport
C7K40_RS08540	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7K40_RS08570	COG3711	transcriptional antiterminator
C7K40_RS08585	COG3942	CHAP domain
C7K40_RS08585	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7K40_RS08590	COG2205	protein histidine kinase activity
C7K40_RS08595	COG0745	RESPONSE REGULATOR receiver
C7K40_RS08600	COG0577	efflux transmembrane transporter activity
C7K40_RS08605	COG1136	(ABC) transporter
C7K40_RS08680	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7K40_RS08695	COG1882	Formate acetyltransferase
C7K40_RS08700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K40_RS08705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7K40_RS08710	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7K40_RS08715	COG2390	Transcriptional regulator
C7K40_RS08720	COG1349	DNA-binding transcription factor activity
C7K40_RS08725	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7K40_RS08745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7K40_RS08760	COG0564	pseudouridine synthase activity
C7K40_RS08795	COG0542	response to heat
C7K40_RS08800	COG4463	regulation of RNA biosynthetic process
C7K40_RS08815	COG0450	alkyl hydroperoxide reductase
C7K40_RS08830	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7K40_RS08840	COG3404	Formiminotransferase-cyclodeaminase
C7K40_RS08855	COG0531	amino acid
C7K40_RS08885	COG3590	peptidase
C7K40_RS08890	COG0366	Alpha amylase catalytic
C7K40_RS08895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7K40_RS08895	COG1263	PTS System
C7K40_RS08900	COG2188	Transcriptional regulator
C7K40_RS08915	COG2514	catechol 2,3-dioxygenase activity
C7K40_RS08925	COG0602	queuosine metabolic process
C7K40_RS08940	COG1328	CTP reductase activity
C7K40_RS08970	COG5433	transposase activity
C7K40_RS08975	COG1393	Belongs to the ArsC family
C7K40_RS08990	COG0519	Catalyzes the synthesis of GMP from XMP
C7K40_RS09010	COG0582	viral genome integration into host DNA
C7K40_RS09140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K40_RS09145	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K40_RS09150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K40_RS09235	COG1511	domain protein
C7K40_RS09255	COG0305	Participates in initiation and elongation during chromosome replication
C7K40_RS09285	COG1760	l-serine dehydratase
C7K40_RS09290	COG1760	l-serine dehydratase
C7K40_RS09295	COG0741	lytic transglycosylase activity
C7K40_RS09300	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
C7K40_RS09315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7K40_RS09325	COG0612	Peptidase, M16
C7K40_RS09350	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7K40_RS09370	COG0516	GMP reductase activity
C7K40_RS09370	COG0517	IMP dehydrogenase activity
C7K40_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7K40_RS09385	COG0488	(ABC) transporter
C7K40_RS09420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7K40_RS09425	COG1475	DNA binding