locus-tag	class	description
HFV09_RS00010	COG0592	DNA-directed DNA polymerase activity
HFV09_RS00020	COG0012	GTP binding
HFV09_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFV09_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HFV09_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFV09_RS00065	COG0531	amino acid
HFV09_RS00245	COG3942	CHAP domain
HFV09_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFV09_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFV09_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFV09_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFV09_RS00330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFV09_RS00345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFV09_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
HFV09_RS00360	COG1454	alcohol dehydrogenase
HFV09_RS00365	COG1064	alcohol dehydrogenase
HFV09_RS00370	COG0534	Mate efflux family protein
HFV09_RS00480	COG0201	protein transport
HFV09_RS00630	COG1121	(ABC) transporter
HFV09_RS00635	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HFV09_RS00650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HFV09_RS00650	COG4499	WXG100 protein secretion system (Wss), protein YukC
HFV09_RS00670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HFV09_RS00675	COG1459	type II secretion system
HFV09_RS00680	COG4537	Required for transformation and DNA binding
HFV09_RS00720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFV09_RS00725	COG1363	Peptidase, m42
HFV09_RS00735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HFV09_RS00740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFV09_RS00750	COG1428	Deoxynucleoside kinase
HFV09_RS00755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFV09_RS00815	COG2031	fatty acid transporter
HFV09_RS00830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFV09_RS00845	COG0251	oxidation-reduction process
HFV09_RS00860	COG1269	ATP hydrolysis coupled proton transport
HFV09_RS00865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFV09_RS00875	COG1527	subunit (C
HFV09_RS00880	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFV09_RS00915	COG1744	ABC transporter substrate-binding protein PnrA-like
HFV09_RS00960	COG0626	cystathionine gamma-synthase activity
HFV09_RS00990	COG3623	hexulose-6-phosphate isomerase
HFV09_RS01010	COG3448	diguanylate cyclase activity
HFV09_RS01010	COG4175	Glycine betaine
HFV09_RS01020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFV09_RS01020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFV09_RS01050	COG1268	BioY protein
HFV09_RS01055	COG1234	tRNA 3'-trailer cleavage
HFV09_RS01090	COG0457	Tetratricopeptide repeat
HFV09_RS01090	COG0705	Rhomboid family
HFV09_RS01110	COG1132	(ABC) transporter
HFV09_RS01115	COG1132	(ABC) transporter
HFV09_RS01125	COG0756	dUTP diphosphatase activity
HFV09_RS01150	COG3290	protein histidine kinase activity
HFV09_RS01175	COG1847	R3H domain protein
HFV09_RS01195	COG1175	transmembrane transport
HFV09_RS01200	COG0395	ABC-type sugar transport system, permease component
HFV09_RS01215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFV09_RS01230	COG0084	hydrolase, TatD family'
HFV09_RS01255	COG1564	THIamine pyrophosphokinase
HFV09_RS01270	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFV09_RS01310	COG0765	amino acid transport
HFV09_RS01330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFV09_RS01340	COG0719	Fe-S assembly protein
HFV09_RS01345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFV09_RS01360	COG1686	Belongs to the peptidase S11 family
HFV09_RS01365	COG1686	Belongs to the peptidase S11 family
HFV09_RS01370	COG4166	transmembrane transport
HFV09_RS01375	COG0601	transmembrane transport
HFV09_RS01380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFV09_RS01385	COG0444	Belongs to the ABC transporter superfamily
HFV09_RS01395	COG2801	Transposase and inactivated derivatives
HFV09_RS01440	COG0351	phosphomethylpyrimidine kinase
HFV09_RS01445	COG4720	Psort location CytoplasmicMembrane, score
HFV09_RS01455	COG0668	transmembrane transport
HFV09_RS01510	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HFV09_RS01525	COG0789	Transcriptional regulator
HFV09_RS01530	COG0174	glutamine synthetase
HFV09_RS01545	COG1214	PFAM Peptidase M22, glycoprotease
HFV09_RS01550	COG0456	acetyltransferase
HFV09_RS01570	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HFV09_RS01575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFV09_RS01585	COG2081	HI0933 family
HFV09_RS01600	COG0789	Transcriptional regulator
HFV09_RS01625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HFV09_RS01630	COG2814	Major facilitator Superfamily
HFV09_RS01635	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HFV09_RS01650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HFV09_RS01655	COG1882	Formate acetyltransferase
HFV09_RS01670	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFV09_RS01675	COG0681	Belongs to the peptidase S26 family
HFV09_RS01705	COG3118	belongs to the thioredoxin family
HFV09_RS01710	COG3620	sequence-specific DNA binding
HFV09_RS01715	COG1194	a g-specific adenine glycosylase
HFV09_RS01755	COG0006	proline dipeptidase activity
HFV09_RS01760	COG2131	deaminase
HFV09_RS01780	COG1609	Transcriptional regulator
HFV09_RS01785	COG1621	beta-fructofuranosidase activity
HFV09_RS01790	COG1263	PTS System
HFV09_RS01790	COG2190	(PTS) system
HFV09_RS01790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HFV09_RS01800	COG1940	carbohydrate kinase activity
HFV09_RS01805	COG1482	cell wall glycoprotein biosynthetic process
HFV09_RS01830	COG1388	LysM domain
HFV09_RS01830	COG3942	CHAP domain
HFV09_RS01855	COG1120	ATPase activity
HFV09_RS01860	COG4988	ABC transporter
HFV09_RS01865	COG1132	(ABC) transporter
HFV09_RS01880	COG1129	ABC transporter
HFV09_RS01885	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFV09_RS01900	COG0252	asparaginase activity
HFV09_RS01905	COG0561	phosphatase activity
HFV09_RS01915	COG0436	Aminotransferase
HFV09_RS01925	COG1335	isochorismatase
HFV09_RS01955	COG2261	transglycosylase associated protein
HFV09_RS01960	COG0588	phosphoglycerate mutase activity
HFV09_RS01990	COG0484	heat shock protein binding
HFV09_RS01995	COG1024	Enoyl-CoA hydratase
HFV09_RS02020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HFV09_RS02025	COG1028	Short-chain dehydrogenase reductase Sdr
HFV09_RS02030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HFV09_RS02045	COG0439	Biotin carboxylase
HFV09_RS02070	COG3716	PTS system mannose fructose sorbose family IID component
HFV09_RS02075	COG3715	PTS system
HFV09_RS02085	COG0561	phosphatase activity
HFV09_RS02090	COG2252	PERMEase
HFV09_RS02095	COG0802	atpase or kinase
HFV09_RS02105	COG1316	TRANSCRIPTIONal
HFV09_RS02115	COG0537	adenosine 5'-monophosphoramidase activity
HFV09_RS02120	COG1131	(ABC) transporter
HFV09_RS02125	COG4473	ABC transporter
HFV09_RS02150	COG0195	Participates in both transcription termination and antitermination
HFV09_RS02155	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HFV09_RS02185	COG2217	Heavy metal translocating P-type atpase
HFV09_RS02225	COG1105	Belongs to the carbohydrate kinase PfkB family
HFV09_RS02235	COG2860	membrane
HFV09_RS02240	COG0561	phosphatase activity
HFV09_RS02260	COG1283	sodium-dependent phosphate transmembrane transporter activity
HFV09_RS02270	COG0656	L-ascorbic acid biosynthetic process
HFV09_RS02275	COG1755	Isoprenylcysteine carboxyl methyltransferase
HFV09_RS02310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HFV09_RS02315	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFV09_RS02340	COG1131	(ABC) transporter
HFV09_RS02375	COG0768	penicillin binding
HFV09_RS02385	COG0513	Belongs to the DEAD box helicase family
HFV09_RS02395	COG1126	abc transporter atp-binding protein
HFV09_RS02405	COG0492	ferredoxin-NADP+ reductase activity
HFV09_RS02410	COG1113	amino acid transport
HFV09_RS02415	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFV09_RS02425	COG3579	cysteine-type endopeptidase activity
HFV09_RS02430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HFV09_RS02455	COG0116	Belongs to the methyltransferase superfamily
HFV09_RS02470	COG2610	gluconate transmembrane transporter activity
HFV09_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
HFV09_RS02485	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFV09_RS02490	COG0183	Belongs to the thiolase family
HFV09_RS02495	COG0583	DNA-binding transcription factor activity
HFV09_RS02515	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFV09_RS02525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFV09_RS02525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFV09_RS02535	COG2815	serine threonine protein kinase
HFV09_RS02535	COG0515	serine threonine protein kinase
HFV09_RS02545	COG4585	Histidine kinase
HFV09_RS02550	COG2197	response regulator
HFV09_RS02560	COG1098	S1 RNA binding domain
HFV09_RS02570	COG1739	Uncharacterized protein family UPF0029
HFV09_RS02575	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HFV09_RS02670	COG0383	alpha-mannosidase activity
HFV09_RS02685	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HFV09_RS02690	COG2723	6-phospho-beta-galactosidase activity
HFV09_RS02695	COG1940	carbohydrate kinase activity
HFV09_RS02700	COG1175	transmembrane transport
HFV09_RS02705	COG0395	ABC-type sugar transport system, permease component
HFV09_RS02720	COG2972	Histidine kinase
HFV09_RS02725	COG4753	response regulator
HFV09_RS02725	COG2207	Transcriptional regulator
HFV09_RS02730	COG3250	beta-galactosidase activity
HFV09_RS02740	COG2226	methyltransferase
HFV09_RS02760	COG1605	Chorismate mutase
HFV09_RS02760	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HFV09_RS02820	COG1518	maintenance of DNA repeat elements
HFV09_RS02825	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFV09_RS02830	COG0785	Cytochrome C biogenesis protein
HFV09_RS02835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HFV09_RS02850	COG2972	Histidine kinase
HFV09_RS02875	COG2235	arginine
HFV09_RS02880	COG0454	-acetyltransferase
HFV09_RS02890	COG1288	antiporter activity
HFV09_RS02895	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HFV09_RS02900	COG0549	Belongs to the carbamate kinase family
HFV09_RS02910	COG0742	ribosomal rna small subunit methyltransferase
HFV09_RS02920	COG3480	Lon protease (S16) C-terminal proteolytic domain
HFV09_RS02925	COG1609	Transcriptional regulator
HFV09_RS02930	COG4470	Protein conserved in bacteria
HFV09_RS02945	COG0783	Belongs to the Dps family
HFV09_RS02955	COG1940	carbohydrate kinase activity
HFV09_RS02960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFV09_RS03000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFV09_RS03015	COG2302	S4 RNA-binding domain
HFV09_RS03020	COG3599	regulation of cell shape
HFV09_RS03035	COG0494	nUDIX hydrolase
HFV09_RS03040	COG0542	response to heat
HFV09_RS03045	COG4703	Protein of unknown function (DUF1797)
HFV09_RS03050	COG0765	amino acid transport
HFV09_RS03065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFV09_RS03090	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HFV09_RS03095	COG1438	arginine binding
HFV09_RS03100	COG0497	DNA recombination
HFV09_RS03115	COG2755	lipolytic protein G-D-S-L family
HFV09_RS03130	COG0582	viral genome integration into host DNA
HFV09_RS03140	COG1396	sequence-specific DNA binding
HFV09_RS03380	COG3177	Filamentation induced by cAMP protein fic
HFV09_RS03395	COG2217	Heavy metal translocating P-type atpase
HFV09_RS03415	COG1827	regulation of RNA biosynthetic process
HFV09_RS03425	COG2116	formate transmembrane transporter activity
HFV09_RS03440	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HFV09_RS03455	COG0513	Belongs to the DEAD box helicase family
HFV09_RS03470	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HFV09_RS03475	COG0204	Acyl-transferase
HFV09_RS03480	COG1555	photosystem II stabilization
HFV09_RS03480	COG1596	polysaccharide export
HFV09_RS03485	COG2333	competence protein COMEC
HFV09_RS03485	COG0658	competence protein
HFV09_RS03530	COG1187	pseudouridine synthase activity
HFV09_RS03545	COG2223	nitrite transmembrane transporter activity
HFV09_RS03550	COG4122	O-methyltransferase activity
HFV09_RS03565	COG1476	TRANSCRIPTIONal
HFV09_RS03600	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFV09_RS03605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HFV09_RS03625	COG0726	polysaccharide deacetylase
HFV09_RS03635	COG0513	Belongs to the DEAD box helicase family
HFV09_RS03655	COG1956	GAF domain-containing protein
HFV09_RS03660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFV09_RS03670	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HFV09_RS03670	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HFV09_RS03695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HFV09_RS03700	COG4109	DRTGG domain
HFV09_RS03750	COG2814	Major facilitator Superfamily
HFV09_RS03760	COG1187	pseudouridine synthase activity
HFV09_RS03765	COG2801	Transposase and inactivated derivatives
HFV09_RS03770	COG2801	Transposase and inactivated derivatives
HFV09_RS03785	COG0157	Belongs to the NadC ModD family
HFV09_RS03815	COG2723	6-phospho-beta-galactosidase activity
HFV09_RS03825	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFV09_RS03825	COG3711	transcriptional antiterminator
HFV09_RS03835	COG1447	Phosphotransferase system cellobiose-specific component IIA
HFV09_RS03845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFV09_RS03855	COG1126	abc transporter atp-binding protein
HFV09_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFV09_RS03880	COG1696	Membrane protein involved in D-alanine export
HFV09_RS03890	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFV09_RS03895	COG0657	acetylesterase activity
HFV09_RS03900	COG2182	Extracellular solute-binding protein
HFV09_RS03905	COG0366	Alpha amylase catalytic
HFV09_RS03915	COG1175	transmembrane transport
HFV09_RS03920	COG3833	ABC-type maltose transport systems, permease component
HFV09_RS03935	COG3833	ABC-type maltose transport systems, permease component
HFV09_RS03940	COG1175	transmembrane transport
HFV09_RS03945	COG2182	Extracellular solute-binding protein
HFV09_RS03950	COG1609	Transcriptional regulator
HFV09_RS03955	COG1640	4-alpha-glucanotransferase
HFV09_RS03960	COG0058	SHG alpha-glucan phosphorylase activity
HFV09_RS03985	COG1131	(ABC) transporter
HFV09_RS03990	COG1725	Transcriptional regulator
HFV09_RS04005	COG0469	pyruvate kinase activity
HFV09_RS04020	COG2824	Alkylphosphonate utilization operon protein PhnA
HFV09_RS04025	COG0765	amino acid transport
HFV09_RS04030	COG1126	abc transporter atp-binding protein
HFV09_RS04035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFV09_RS04045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFV09_RS04050	COG1115	amino acid carrier protein
HFV09_RS04100	COG1136	(ABC) transporter
HFV09_RS04100	COG4591	ABC-type transport system involved in lipoprotein release permease component
HFV09_RS04130	COG0196	riboflavin kinase activity
HFV09_RS04145	COG0483	inositol monophosphate 1-phosphatase activity
HFV09_RS04150	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HFV09_RS04150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFV09_RS04160	COG0573	inorganic phosphate transmembrane transporter activity
HFV09_RS04165	COG0581	inorganic phosphate transmembrane transporter activity
HFV09_RS04180	COG0704	Plays a role in the regulation of phosphate uptake
HFV09_RS04190	COG0745	RESPONSE REGULATOR receiver
HFV09_RS04195	COG5002	protein histidine kinase activity
HFV09_RS04210	COG2813	Specifically methylates the guanine in position
HFV09_RS04215	COG0295	cytidine deaminase activity
HFV09_RS04220	COG1744	ABC transporter substrate-binding protein PnrA-like
HFV09_RS04240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFV09_RS04245	COG4684	Psort location CytoplasmicMembrane, score
HFV09_RS04250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFV09_RS04260	COG0095	Lipoate-protein ligase
HFV09_RS04270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFV09_RS04300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFV09_RS04305	COG1328	CTP reductase activity
HFV09_RS04305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFV09_RS04310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFV09_RS04315	COG0352	thiamine-phosphate diphosphorylase activity
HFV09_RS04315	COG0351	phosphomethylpyrimidine kinase
HFV09_RS04325	COG0488	(ABC) transporter
HFV09_RS04345	COG2188	Transcriptional regulator
HFV09_RS04355	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFV09_RS04375	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HFV09_RS04405	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HFV09_RS04410	COG0511	ligase activity, forming carbon-carbon bonds
HFV09_RS04420	COG2851	Citrate transporter
HFV09_RS04435	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HFV09_RS04440	COG0511	ligase activity, forming carbon-carbon bonds
HFV09_RS04485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFV09_RS04490	COG0758	DNA mediated transformation
HFV09_RS04510	COG1272	protein, Hemolysin III
HFV09_RS04525	COG0346	lactoylglutathione lyase activity
HFV09_RS04530	COG3764	Sortase (surface protein transpeptidase)
HFV09_RS04550	COG1132	(ABC) transporter
HFV09_RS04555	COG1132	(ABC) transporter
HFV09_RS04585	COG2890	protein-(glutamine-N5) methyltransferase activity
HFV09_RS04610	COG2233	PERMEase
HFV09_RS04625	COG1174	glycine betaine transport
HFV09_RS04640	COG4221	oxidoreductase activity
HFV09_RS04645	COG0280	phosphate acetyltransferase
HFV09_RS04650	COG0564	pseudouridine synthase activity
HFV09_RS04660	COG2357	RelA SpoT domain protein
HFV09_RS04675	COG1104	cysteine desulfurase activity
HFV09_RS04690	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HFV09_RS04700	COG0628	permease
HFV09_RS04710	COG0038	chloride channel
HFV09_RS04715	COG3700	Belongs to the class B bacterial acid phosphatase family
HFV09_RS04730	COG3493	citrate carrier protein
HFV09_RS04735	COG3290	protein histidine kinase activity
HFV09_RS04740	COG4565	transcriptional regulatory protein
HFV09_RS04750	COG1177	transmembrane transport
HFV09_RS04755	COG1176	ABC-type spermidine putrescine transport system, permease component I
HFV09_RS04770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFV09_RS04790	COG0285	dihydrofolate synthase activity
HFV09_RS04820	COG1396	sequence-specific DNA binding
HFV09_RS04835	COG1131	(ABC) transporter
HFV09_RS04905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HFV09_RS04920	COG1012	belongs to the aldehyde dehydrogenase family
HFV09_RS04930	COG4753	response regulator
HFV09_RS04930	COG2207	Transcriptional regulator
HFV09_RS04935	COG2972	Histidine kinase
HFV09_RS04940	COG3716	PTS system mannose fructose sorbose family IID component
HFV09_RS04945	COG3715	PTS system
HFV09_RS04990	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HFV09_RS04995	COG1518	maintenance of DNA repeat elements
HFV09_RS05010	COG0647	UMP catabolic process
HFV09_RS05020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HFV09_RS05040	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFV09_RS05045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HFV09_RS05050	COG3442	glutamine amidotransferase
HFV09_RS05055	COG0095	Lipoate-protein ligase
HFV09_RS05060	COG5492	domain, Protein
HFV09_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFV09_RS05075	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFV09_RS05075	COG0022	dehydrogenase e1 component
HFV09_RS05080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HFV09_RS05085	COG0488	(ABC) transporter
HFV09_RS05105	COG1129	ABC transporter
HFV09_RS05120	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HFV09_RS05125	COG0457	Tetratricopeptide repeat
HFV09_RS05130	COG0628	permease
HFV09_RS05135	COG1051	belongs to the nudix hydrolase family
HFV09_RS05280	COG1783	phage Terminase large subunit
HFV09_RS05405	COG0582	viral genome integration into host DNA
HFV09_RS05410	COG1088	dTDP-glucose 4,6-dehydratase activity
HFV09_RS05420	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFV09_RS05425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFV09_RS05435	COG2384	SAM-dependent methyltransferase
HFV09_RS05440	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFV09_RS05455	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HFV09_RS05455	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HFV09_RS05460	COG0300	oxidoreductase activity
HFV09_RS05470	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HFV09_RS05475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFV09_RS05520	COG0539	negative regulation of cytoplasmic translation
HFV09_RS05545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HFV09_RS05555	COG0187	DNA topoisomerase II activity
HFV09_RS05575	COG0765	amino acid transport
HFV09_RS05580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFV09_RS05605	COG0583	DNA-binding transcription factor activity
HFV09_RS05660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFV09_RS05670	COG3425	synthase
HFV09_RS05705	COG0745	RESPONSE REGULATOR receiver
HFV09_RS05710	COG2357	RelA SpoT domain protein
HFV09_RS05715	COG0737	Belongs to the 5'-nucleotidase family
HFV09_RS05720	COG0242	peptide deformylase activity
HFV09_RS05725	COG0488	(ABC) transporter
HFV09_RS05765	COG1388	LysM domain
HFV09_RS05765	COG1705	Flagellar rod assembly protein muramidase FlgJ
HFV09_RS05770	COG1388	LysM domain
HFV09_RS05770	COG1705	Flagellar rod assembly protein muramidase FlgJ
HFV09_RS05775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFV09_RS05775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFV09_RS05775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFV09_RS05780	COG1105	Belongs to the carbohydrate kinase PfkB family
HFV09_RS05785	COG1349	DNA-binding transcription factor activity
HFV09_RS05840	COG1837	Belongs to the UPF0109 family
HFV09_RS05855	COG0577	efflux transmembrane transporter activity
HFV09_RS05860	COG1136	(ABC) transporter
HFV09_RS05865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFV09_RS05895	COG0564	pseudouridine synthase activity
HFV09_RS05905	COG0583	DNA-binding transcription factor activity
HFV09_RS05910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HFV09_RS05940	COG1104	cysteine desulfurase activity
HFV09_RS05950	COG0285	dihydrofolate synthase activity
HFV09_RS05955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFV09_RS05975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HFV09_RS05980	COG1368	sulfuric ester hydrolase activity
HFV09_RS06040	COG1216	Glycosyl transferase, family 2
HFV09_RS06085	COG2151	metal-sulfur cluster biosynthetic enzyme
HFV09_RS06090	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFV09_RS06095	COG0358	DNA primase activity
HFV09_RS06105	COG1970	mechanosensitive ion channel activity
HFV09_RS06115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFV09_RS06130	COG2321	neutral zinc metallopeptidase
HFV09_RS06135	COG1136	(ABC) transporter
HFV09_RS06140	COG0577	efflux transmembrane transporter activity
HFV09_RS06225	COG1597	lipid kinase activity
HFV09_RS06235	COG4708	membrane
HFV09_RS06255	COG1131	(ABC) transporter
HFV09_RS06340	COG0038	chloride channel
HFV09_RS06350	COG0716	FMN binding
HFV09_RS06355	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HFV09_RS06365	COG2222	sugar isomerase
HFV09_RS06370	COG2188	Transcriptional regulator
HFV09_RS06400	COG1705	Flagellar rod assembly protein muramidase FlgJ
HFV09_RS06490	COG0740	serine-type endopeptidase activity
HFV09_RS06535	COG1598	PFAM Uncharacterised protein family UPF0150
HFV09_RS06725	COG0436	Aminotransferase
HFV09_RS06730	COG1199	ATP-dependent helicase activity
HFV09_RS06730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFV09_RS06745	COG2177	Part of the ABC transporter FtsEX involved in
HFV09_RS06750	COG2884	Cell division ATP-binding protein ftsE
HFV09_RS06760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFV09_RS06770	COG0546	phosphoglycolate phosphatase activity
HFV09_RS06775	COG0800	Aldolase
HFV09_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
HFV09_RS06805	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HFV09_RS06810	COG3715	PTS system
HFV09_RS06815	COG3716	PTS system mannose fructose sorbose family IID component
HFV09_RS06825	COG1609	Transcriptional regulator
HFV09_RS06840	COG1078	dGTPase activity
HFV09_RS06870	COG0772	Belongs to the SEDS family
HFV09_RS06880	COG1164	Oligoendopeptidase f
HFV09_RS06885	COG0386	Belongs to the glutathione peroxidase family
HFV09_RS06935	COG4443	Transcriptional Coactivator p15 (PC4)
HFV09_RS06985	COG2183	response to ionizing radiation
HFV09_RS06995	COG0701	Predicted permease
HFV09_RS07000	COG3689	TIGRFAM TIGR03943 family protein
HFV09_RS07010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HFV09_RS07010	COG2190	(PTS) system
HFV09_RS07010	COG1263	PTS System
HFV09_RS07015	COG3711	transcriptional antiterminator
HFV09_RS07020	COG0477	Major facilitator Superfamily
HFV09_RS07025	COG0552	protein localization to endoplasmic reticulum
HFV09_RS07030	COG0561	phosphatase activity
HFV09_RS07035	COG0561	phosphatase activity
HFV09_RS07175	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFV09_RS07190	COG1196	nuclear chromosome segregation
HFV09_RS07200	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HFV09_RS07205	COG5002	protein histidine kinase activity
HFV09_RS07210	COG0745	RESPONSE REGULATOR receiver
HFV09_RS07225	COG0183	Belongs to the thiolase family
HFV09_RS07235	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HFV09_RS07240	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
HFV09_RS07245	COG1461	Dihydroxyacetone kinase
HFV09_RS07250	COG2376	Dihydroxyacetone kinase
HFV09_RS07260	COG2376	Dihydroxyacetone kinase
HFV09_RS07275	COG4555	ABC transporter
HFV09_RS07285	COG0438	transferase activity, transferring glycosyl groups
HFV09_RS07295	COG1609	Transcriptional regulator
HFV09_RS07300	COG0006	proline dipeptidase activity
HFV09_RS07305	COG0778	Nitroreductase
HFV09_RS07315	COG0463	Glycosyl transferase, family 2
HFV09_RS07345	COG0557	exoribonuclease II activity
HFV09_RS07360	COG2814	Major facilitator Superfamily
HFV09_RS07365	COG0433	COG0433 Predicted ATPase
HFV09_RS07445	COG2274	protein secretion by the type I secretion system
HFV09_RS07465	COG3279	Response regulator of the LytR AlgR family
HFV09_RS07470	COG2801	Transposase and inactivated derivatives
HFV09_RS07475	COG2801	Transposase and inactivated derivatives
HFV09_RS07480	COG2801	Transposase and inactivated derivatives
HFV09_RS07515	COG2274	protein secretion by the type I secretion system
HFV09_RS07520	COG2274	protein secretion by the type I secretion system
HFV09_RS07525	COG2274	protein secretion by the type I secretion system
HFV09_RS07545	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HFV09_RS07555	COG1573	uracil-dna glycosylase
HFV09_RS07560	COG1702	phosphate starvation-inducible protein PhoH
HFV09_RS07650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFV09_RS07660	COG0494	nUDIX hydrolase
HFV09_RS07675	COG0673	inositol 2-dehydrogenase activity
HFV09_RS07680	COG1028	Short-chain dehydrogenase reductase Sdr
HFV09_RS07760	COG0708	Exodeoxyribonuclease III
HFV09_RS07765	COG1393	Belongs to the ArsC family
HFV09_RS07795	COG0470	DNA polymerase III
HFV09_RS07820	COG2244	polysaccharide biosynthetic process
HFV09_RS07835	COG1120	ATPase activity
HFV09_RS07840	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HFV09_RS07845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFV09_RS07850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFV09_RS07865	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFV09_RS07870	COG1253	flavin adenine dinucleotide binding
HFV09_RS07875	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HFV09_RS07880	COG1242	4 iron, 4 sulfur cluster binding
HFV09_RS07885	COG0671	phosphoesterase, PA-phosphatase related
HFV09_RS07890	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFV09_RS07905	COG1187	pseudouridine synthase activity
HFV09_RS07960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFV09_RS07965	COG1254	Belongs to the acylphosphatase family
HFV09_RS07980	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFV09_RS08000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HFV09_RS08010	COG1484	DNA-dependent DNA replication
HFV09_RS08030	COG0745	RESPONSE REGULATOR receiver
HFV09_RS08045	COG1704	LemA family
HFV09_RS08055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HFV09_RS08060	COG0569	domain protein
HFV09_RS08070	COG1114	Component of the transport system for branched-chain amino acids
HFV09_RS08085	COG1464	Belongs to the NlpA lipoprotein family
HFV09_RS08090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFV09_RS08105	COG2226	methyltransferase
HFV09_RS08110	COG0799	negative regulation of ribosome biogenesis
HFV09_RS08120	COG1713	HD superfamily hydrolase involved in NAD metabolism
HFV09_RS08130	COG1534	Rna-binding protein
HFV09_RS08135	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFV09_RS08140	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HFV09_RS08180	COG1929	Belongs to the glycerate kinase type-1 family
HFV09_RS08185	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HFV09_RS08210	COG0577	efflux transmembrane transporter activity
HFV09_RS08215	COG1136	(ABC) transporter
HFV09_RS08220	COG2274	protein secretion by the type I secretion system
HFV09_RS08240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFV09_RS08240	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFV09_RS08245	COG1447	Phosphotransferase system cellobiose-specific component IIA
HFV09_RS08295	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFV09_RS08300	COG1476	TRANSCRIPTIONal
HFV09_RS08320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFV09_RS08330	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFV09_RS08345	COG1045	serine acetyltransferase
HFV09_RS08360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFV09_RS08375	COG3711	transcriptional antiterminator
HFV09_RS08400	COG0431	NADPH-dependent FMN reductase
HFV09_RS08405	COG1846	Transcriptional regulator
HFV09_RS08425	COG4589	Belongs to the CDS family
HFV09_RS08435	COG1862	Preprotein translocase
HFV09_RS08445	COG1523	belongs to the glycosyl hydrolase 13 family
HFV09_RS08455	COG3842	ATPase activity
HFV09_RS08500	COG2190	(PTS) system
HFV09_RS08500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HFV09_RS08500	COG1263	PTS System
HFV09_RS08505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HFV09_RS08525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFV09_RS08530	COG0512	Glutamine amidotransferase of anthranilate synthase
HFV09_RS08535	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HFV09_RS08575	COG0601	transmembrane transport
HFV09_RS08585	COG1122	ATPase activity
HFV09_RS08605	COG0803	Belongs to the bacterial solute-binding protein 9 family
HFV09_RS08645	COG1705	Flagellar rod assembly protein muramidase FlgJ
HFV09_RS08645	COG3942	CHAP domain
HFV09_RS08650	COG2205	protein histidine kinase activity
HFV09_RS08655	COG0745	RESPONSE REGULATOR receiver
HFV09_RS08660	COG0577	efflux transmembrane transporter activity
HFV09_RS08665	COG1136	(ABC) transporter
HFV09_RS08735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HFV09_RS08750	COG1882	Formate acetyltransferase
HFV09_RS08755	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFV09_RS08760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HFV09_RS08765	COG1447	Phosphotransferase system cellobiose-specific component IIA
HFV09_RS08770	COG2390	Transcriptional regulator
HFV09_RS08775	COG1349	DNA-binding transcription factor activity
HFV09_RS08780	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFV09_RS08795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HFV09_RS08805	COG0564	pseudouridine synthase activity
HFV09_RS08835	COG0542	response to heat
HFV09_RS08840	COG4463	regulation of RNA biosynthetic process
HFV09_RS08855	COG0450	alkyl hydroperoxide reductase
HFV09_RS08870	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HFV09_RS08880	COG3404	Formiminotransferase-cyclodeaminase
HFV09_RS08895	COG0531	amino acid
HFV09_RS08925	COG3590	peptidase
HFV09_RS08930	COG0366	Alpha amylase catalytic
HFV09_RS08935	COG1263	PTS System
HFV09_RS08935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HFV09_RS08940	COG2188	Transcriptional regulator
HFV09_RS08945	COG1733	regulation of RNA biosynthetic process
HFV09_RS08950	COG2514	catechol 2,3-dioxygenase activity
HFV09_RS08960	COG0602	queuosine metabolic process
HFV09_RS08980	COG1328	CTP reductase activity
HFV09_RS09005	COG1393	Belongs to the ArsC family
HFV09_RS09020	COG0519	Catalyzes the synthesis of GMP from XMP
HFV09_RS09040	COG0582	viral genome integration into host DNA
HFV09_RS09055	COG1396	sequence-specific DNA binding
HFV09_RS09060	COG3617	BRO family, N-terminal domain
HFV09_RS09195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFV09_RS09200	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFV09_RS09205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFV09_RS09290	COG1511	domain protein
HFV09_RS09310	COG0305	Participates in initiation and elongation during chromosome replication
HFV09_RS09340	COG1760	l-serine dehydratase
HFV09_RS09345	COG1760	l-serine dehydratase
HFV09_RS09350	COG0741	lytic transglycosylase activity
HFV09_RS09355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFV09_RS09370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFV09_RS09380	COG0612	Peptidase, M16
HFV09_RS09405	COG0516	GMP reductase activity
HFV09_RS09405	COG0517	IMP dehydrogenase activity
HFV09_RS09415	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFV09_RS09420	COG0488	(ABC) transporter
HFV09_RS09455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFV09_RS09460	COG1475	DNA binding