locus-tag	class	description
A20_RS00010	COG0592	DNA-directed DNA polymerase activity
A20_RS00020	COG0012	GTP binding
A20_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A20_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A20_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A20_RS00065	COG0531	amino acid
A20_RS00240	COG3942	CHAP domain
A20_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A20_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A20_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A20_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A20_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A20_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A20_RS00350	COG1454	alcohol dehydrogenase
A20_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
A20_RS00355	COG1064	alcohol dehydrogenase
A20_RS00360	COG0534	Mate efflux family protein
A20_RS00470	COG0201	protein transport
A20_RS00605	COG1121	(ABC) transporter
A20_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A20_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A20_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A20_RS00650	COG1459	type II secretion system
A20_RS00655	COG4537	Required for transformation and DNA binding
A20_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A20_RS00700	COG1363	Peptidase, m42
A20_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A20_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A20_RS00725	COG1428	Deoxynucleoside kinase
A20_RS00730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A20_RS00760	COG4509	Sortase family
A20_RS00770	COG4372	Transposase
A20_RS00795	COG2031	fatty acid transporter
A20_RS00815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A20_RS00830	COG0251	oxidation-reduction process
A20_RS00845	COG1269	ATP hydrolysis coupled proton transport
A20_RS00850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A20_RS00860	COG1527	subunit (C
A20_RS00865	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A20_RS00900	COG1744	ABC transporter substrate-binding protein PnrA-like
A20_RS00940	COG0626	cystathionine gamma-synthase activity
A20_RS00970	COG3623	hexulose-6-phosphate isomerase
A20_RS00990	COG4175	Glycine betaine
A20_RS00990	COG3448	diguanylate cyclase activity
A20_RS01000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A20_RS01000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A20_RS01020	COG3969	phosphoadenosine phosphosulfate
A20_RS01025	COG1475	DNA binding
A20_RS01035	COG2801	Transposase and inactivated derivatives
A20_RS01040	COG2801	Transposase and inactivated derivatives
A20_RS01055	COG0157	Belongs to the NadC ModD family
A20_RS01060	COG2801	Transposase and inactivated derivatives
A20_RS01080	COG1268	BioY protein
A20_RS01085	COG1234	tRNA 3'-trailer cleavage
A20_RS01115	COG5433	transposase activity
A20_RS01125	COG0457	Tetratricopeptide repeat
A20_RS01125	COG0705	Rhomboid family
A20_RS01145	COG1132	(ABC) transporter
A20_RS01150	COG1132	(ABC) transporter
A20_RS01160	COG0756	dUTP diphosphatase activity
A20_RS01185	COG3290	protein histidine kinase activity
A20_RS01210	COG1847	R3H domain protein
A20_RS01230	COG1175	transmembrane transport
A20_RS01235	COG0395	ABC-type sugar transport system, permease component
A20_RS01245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A20_RS01260	COG0084	hydrolase, TatD family'
A20_RS01285	COG1564	THIamine pyrophosphokinase
A20_RS01300	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A20_RS01335	COG0765	amino acid transport
A20_RS01355	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A20_RS01365	COG0719	Fe-S assembly protein
A20_RS01370	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A20_RS01385	COG1686	Belongs to the peptidase S11 family
A20_RS01390	COG1686	Belongs to the peptidase S11 family
A20_RS01395	COG4166	transmembrane transport
A20_RS01400	COG0601	transmembrane transport
A20_RS01405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A20_RS01410	COG0444	Belongs to the ABC transporter superfamily
A20_RS01460	COG5433	transposase activity
A20_RS01475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A20_RS01480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A20_RS01485	COG1534	Rna-binding protein
A20_RS01495	COG1713	HD superfamily hydrolase involved in NAD metabolism
A20_RS01500	COG0799	negative regulation of ribosome biogenesis
A20_RS01505	COG2226	methyltransferase
A20_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A20_RS01525	COG1464	Belongs to the NlpA lipoprotein family
A20_RS01540	COG1114	Component of the transport system for branched-chain amino acids
A20_RS01550	COG0569	domain protein
A20_RS01555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A20_RS01565	COG1704	LemA family
A20_RS01580	COG0745	RESPONSE REGULATOR receiver
A20_RS01600	COG1484	DNA-dependent DNA replication
A20_RS01610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A20_RS01630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A20_RS01645	COG1254	Belongs to the acylphosphatase family
A20_RS01655	COG5433	transposase activity
A20_RS01660	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A20_RS01715	COG1187	pseudouridine synthase activity
A20_RS01730	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A20_RS01735	COG0671	phosphoesterase, PA-phosphatase related
A20_RS01740	COG1242	4 iron, 4 sulfur cluster binding
A20_RS01745	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A20_RS01750	COG1253	flavin adenine dinucleotide binding
A20_RS01755	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A20_RS01770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A20_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A20_RS01780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A20_RS01785	COG1120	ATPase activity
A20_RS01795	COG2244	polysaccharide biosynthetic process
A20_RS01820	COG0470	DNA polymerase III
A20_RS01855	COG1393	Belongs to the ArsC family
A20_RS01860	COG0708	Exodeoxyribonuclease III
A20_RS01870	COG1304	FMN binding
A20_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
A20_RS01955	COG0673	inositol 2-dehydrogenase activity
A20_RS01970	COG0494	nUDIX hydrolase
A20_RS01980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A20_RS02070	COG1702	phosphate starvation-inducible protein PhoH
A20_RS02075	COG1573	uracil-dna glycosylase
A20_RS02085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A20_RS02110	COG3328	transposase activity
A20_RS02165	COG0433	COG0433 Predicted ATPase
A20_RS02170	COG2814	Major facilitator Superfamily
A20_RS02180	COG0557	exoribonuclease II activity
A20_RS02210	COG0463	Glycosyl transferase, family 2
A20_RS02220	COG0778	Nitroreductase
A20_RS02225	COG0006	proline dipeptidase activity
A20_RS02230	COG1609	Transcriptional regulator
A20_RS02240	COG0438	transferase activity, transferring glycosyl groups
A20_RS02250	COG4555	ABC transporter
A20_RS02270	COG0183	Belongs to the thiolase family
A20_RS02285	COG0745	RESPONSE REGULATOR receiver
A20_RS02290	COG5002	protein histidine kinase activity
A20_RS02295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A20_RS02305	COG1196	nuclear chromosome segregation
A20_RS02315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A20_RS02395	COG4695	Portal protein
A20_RS02445	COG0561	phosphatase activity
A20_RS02450	COG0561	phosphatase activity
A20_RS02455	COG0552	protein localization to endoplasmic reticulum
A20_RS02460	COG0477	Major facilitator Superfamily
A20_RS02465	COG3711	transcriptional antiterminator
A20_RS02470	COG1263	PTS System
A20_RS02470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A20_RS02470	COG2190	(PTS) system
A20_RS02480	COG3689	TIGRFAM TIGR03943 family protein
A20_RS02485	COG0701	Predicted permease
A20_RS02495	COG2183	response to ionizing radiation
A20_RS02540	COG0826	peptidase U32
A20_RS02545	COG4443	Transcriptional Coactivator p15 (PC4)
A20_RS02595	COG0386	Belongs to the glutathione peroxidase family
A20_RS02600	COG1164	Oligoendopeptidase f
A20_RS02610	COG0772	Belongs to the SEDS family
A20_RS02645	COG1078	dGTPase activity
A20_RS02660	COG1609	Transcriptional regulator
A20_RS02670	COG3716	PTS system mannose fructose sorbose family IID component
A20_RS02675	COG3715	PTS system
A20_RS02680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A20_RS02695	COG1028	Short-chain dehydrogenase reductase Sdr
A20_RS02710	COG0800	Aldolase
A20_RS02715	COG0546	phosphoglycolate phosphatase activity
A20_RS02720	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A20_RS02730	COG2884	Cell division ATP-binding protein ftsE
A20_RS02735	COG2177	Part of the ABC transporter FtsEX involved in
A20_RS02750	COG1199	ATP-dependent helicase activity
A20_RS02750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A20_RS02755	COG0436	Aminotransferase
A20_RS02790	COG2188	Transcriptional regulator
A20_RS02795	COG2222	sugar isomerase
A20_RS02805	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A20_RS02810	COG0716	FMN binding
A20_RS02820	COG0038	chloride channel
A20_RS02910	COG1131	(ABC) transporter
A20_RS02930	COG4708	membrane
A20_RS02940	COG1597	lipid kinase activity
A20_RS03025	COG0577	efflux transmembrane transporter activity
A20_RS03035	COG2321	neutral zinc metallopeptidase
A20_RS03050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A20_RS03060	COG1970	mechanosensitive ion channel activity
A20_RS03065	COG0358	DNA primase activity
A20_RS03070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A20_RS03075	COG2151	metal-sulfur cluster biosynthetic enzyme
A20_RS03120	COG1216	Glycosyl transferase, family 2
A20_RS03175	COG1368	sulfuric ester hydrolase activity
A20_RS03180	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A20_RS03200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A20_RS03205	COG0285	dihydrofolate synthase activity
A20_RS03215	COG1104	cysteine desulfurase activity
A20_RS03240	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A20_RS03245	COG0583	DNA-binding transcription factor activity
A20_RS03255	COG0564	pseudouridine synthase activity
A20_RS03285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A20_RS03290	COG1136	(ABC) transporter
A20_RS03295	COG0577	efflux transmembrane transporter activity
A20_RS03300	COG0584	glycerophosphoryl diester phosphodiesterase
A20_RS03310	COG1837	Belongs to the UPF0109 family
A20_RS03360	COG1349	DNA-binding transcription factor activity
A20_RS03365	COG1105	Belongs to the carbohydrate kinase PfkB family
A20_RS03370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A20_RS03370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A20_RS03370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A20_RS03375	COG1705	Flagellar rod assembly protein muramidase FlgJ
A20_RS03375	COG1388	LysM domain
A20_RS03380	COG1705	Flagellar rod assembly protein muramidase FlgJ
A20_RS03380	COG1388	LysM domain
A20_RS03385	COG2801	Transposase and inactivated derivatives
A20_RS03400	COG0105	UTP biosynthetic process
A20_RS03420	COG0488	(ABC) transporter
A20_RS03430	COG0242	peptide deformylase activity
A20_RS03435	COG0737	Belongs to the 5'-nucleotidase family
A20_RS03440	COG2357	RelA SpoT domain protein
A20_RS03445	COG0745	RESPONSE REGULATOR receiver
A20_RS03480	COG3425	synthase
A20_RS03490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A20_RS03550	COG0583	DNA-binding transcription factor activity
A20_RS03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A20_RS03580	COG0765	amino acid transport
A20_RS03600	COG0187	DNA topoisomerase II activity
A20_RS03610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A20_RS03630	COG0539	negative regulation of cytoplasmic translation
A20_RS03665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A20_RS03670	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A20_RS03680	COG0300	oxidoreductase activity
A20_RS03685	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A20_RS03685	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A20_RS03700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A20_RS03705	COG2384	SAM-dependent methyltransferase
A20_RS03715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A20_RS03720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A20_RS03730	COG1088	dTDP-glucose 4,6-dehydratase activity
A20_RS03735	COG1051	belongs to the nudix hydrolase family
A20_RS03740	COG0628	permease
A20_RS03745	COG0457	Tetratricopeptide repeat
A20_RS03750	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A20_RS03765	COG1129	ABC transporter
A20_RS03785	COG0488	(ABC) transporter
A20_RS03790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A20_RS03795	COG0022	dehydrogenase e1 component
A20_RS03795	COG0508	dehydrogenase complex catalyzes the overall conversion of
A20_RS03815	COG5492	domain, Protein
A20_RS03820	COG0095	Lipoate-protein ligase
A20_RS03825	COG3442	glutamine amidotransferase
A20_RS03830	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A20_RS03835	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A20_RS03855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A20_RS03865	COG0647	UMP catabolic process
A20_RS03880	COG1518	maintenance of DNA repeat elements
A20_RS03885	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A20_RS03900	COG0105	UTP biosynthetic process
A20_RS03935	COG3715	PTS system
A20_RS03940	COG3716	PTS system mannose fructose sorbose family IID component
A20_RS03945	COG2972	Histidine kinase
A20_RS03950	COG2207	Transcriptional regulator
A20_RS03950	COG4753	response regulator
A20_RS03955	COG1840	ABC-type Fe3 transport system, periplasmic component
A20_RS03970	COG1011	Hydrolase
A20_RS03975	COG1012	belongs to the aldehyde dehydrogenase family
A20_RS03990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A20_RS04050	COG1131	(ABC) transporter
A20_RS04065	COG1396	sequence-specific DNA binding
A20_RS04105	COG0285	dihydrofolate synthase activity
A20_RS04125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A20_RS04140	COG1176	ABC-type spermidine putrescine transport system, permease component I
A20_RS04145	COG1177	transmembrane transport
A20_RS04155	COG4565	transcriptional regulatory protein
A20_RS04160	COG3290	protein histidine kinase activity
A20_RS04165	COG3493	citrate carrier protein
A20_RS04180	COG3700	Belongs to the class B bacterial acid phosphatase family
A20_RS04185	COG0038	chloride channel
A20_RS04195	COG0628	permease
A20_RS04205	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A20_RS04220	COG1104	cysteine desulfurase activity
A20_RS04235	COG2357	RelA SpoT domain protein
A20_RS04245	COG0564	pseudouridine synthase activity
A20_RS04250	COG0280	phosphate acetyltransferase
A20_RS04270	COG1174	glycine betaine transport
A20_RS04285	COG2233	PERMEase
A20_RS04310	COG2890	protein-(glutamine-N5) methyltransferase activity
A20_RS04340	COG1132	(ABC) transporter
A20_RS04345	COG1132	(ABC) transporter
A20_RS04365	COG3764	Sortase (surface protein transpeptidase)
A20_RS04370	COG0346	lactoylglutathione lyase activity
A20_RS04385	COG1272	protein, Hemolysin III
A20_RS04405	COG0758	DNA mediated transformation
A20_RS04410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A20_RS04455	COG0511	ligase activity, forming carbon-carbon bonds
A20_RS04460	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A20_RS04475	COG2851	Citrate transporter
A20_RS04485	COG0511	ligase activity, forming carbon-carbon bonds
A20_RS04490	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A20_RS04525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A20_RS04545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A20_RS04555	COG2188	Transcriptional regulator
A20_RS04575	COG0488	(ABC) transporter
A20_RS04585	COG0352	thiamine-phosphate diphosphorylase activity
A20_RS04585	COG0351	phosphomethylpyrimidine kinase
A20_RS04590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A20_RS04595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A20_RS04595	COG1328	CTP reductase activity
A20_RS04600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A20_RS04630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A20_RS04650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A20_RS04655	COG4684	Psort location CytoplasmicMembrane, score
A20_RS04660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A20_RS04665	COG1079	Belongs to the binding-protein-dependent transport system permease family
A20_RS04670	COG4603	Belongs to the binding-protein-dependent transport system permease family
A20_RS04675	COG3845	ABC transporter
A20_RS04680	COG1744	ABC transporter substrate-binding protein PnrA-like
A20_RS04685	COG0295	cytidine deaminase activity
A20_RS04690	COG2813	Specifically methylates the guanine in position
A20_RS04705	COG5002	protein histidine kinase activity
A20_RS04710	COG0745	RESPONSE REGULATOR receiver
A20_RS04720	COG0704	Plays a role in the regulation of phosphate uptake
A20_RS04735	COG0581	inorganic phosphate transmembrane transporter activity
A20_RS04740	COG0573	inorganic phosphate transmembrane transporter activity
A20_RS04750	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A20_RS04750	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A20_RS04755	COG0483	inositol monophosphate 1-phosphatase activity
A20_RS04770	COG0196	riboflavin kinase activity
A20_RS04800	COG4591	ABC-type transport system involved in lipoprotein release permease component
A20_RS04800	COG1136	(ABC) transporter
A20_RS04850	COG1115	amino acid carrier protein
A20_RS04855	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A20_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A20_RS04870	COG1126	abc transporter atp-binding protein
A20_RS04875	COG0765	amino acid transport
A20_RS04880	COG2824	Alkylphosphonate utilization operon protein PhnA
A20_RS04895	COG0469	pyruvate kinase activity
A20_RS04910	COG1725	Transcriptional regulator
A20_RS04915	COG1131	(ABC) transporter
A20_RS05070	COG1783	phage Terminase large subunit
A20_RS05175	COG1396	sequence-specific DNA binding
A20_RS05215	COG0058	SHG alpha-glucan phosphorylase activity
A20_RS05220	COG1640	4-alpha-glucanotransferase
A20_RS05225	COG1609	Transcriptional regulator
A20_RS05230	COG2182	Extracellular solute-binding protein
A20_RS05235	COG1175	transmembrane transport
A20_RS05240	COG3833	ABC-type maltose transport systems, permease component
A20_RS05255	COG3833	ABC-type maltose transport systems, permease component
A20_RS05260	COG1175	transmembrane transport
A20_RS05270	COG0366	Alpha amylase catalytic
A20_RS05275	COG2182	Extracellular solute-binding protein
A20_RS05285	COG0657	acetylesterase activity
A20_RS05290	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A20_RS05300	COG1696	Membrane protein involved in D-alanine export
A20_RS05320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A20_RS05325	COG1126	abc transporter atp-binding protein
A20_RS05330	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A20_RS05340	COG1447	Phosphotransferase system cellobiose-specific component IIA
A20_RS05350	COG3711	transcriptional antiterminator
A20_RS05350	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A20_RS05360	COG2723	6-phospho-beta-galactosidase activity
A20_RS05385	COG2801	Transposase and inactivated derivatives
A20_RS05390	COG1187	pseudouridine synthase activity
A20_RS05400	COG2814	Major facilitator Superfamily
A20_RS05450	COG4109	DRTGG domain
A20_RS05480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A20_RS05480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A20_RS05485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A20_RS05490	COG1956	GAF domain-containing protein
A20_RS05510	COG0513	Belongs to the DEAD box helicase family
A20_RS05515	COG0726	polysaccharide deacetylase
A20_RS05535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A20_RS05540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A20_RS05545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A20_RS05560	COG2801	Transposase and inactivated derivatives
A20_RS05570	COG2801	Transposase and inactivated derivatives
A20_RS05585	COG1476	TRANSCRIPTIONal
A20_RS05600	COG4122	O-methyltransferase activity
A20_RS05605	COG2223	nitrite transmembrane transporter activity
A20_RS05620	COG1187	pseudouridine synthase activity
A20_RS05665	COG0658	competence protein
A20_RS05665	COG2333	competence protein COMEC
A20_RS05670	COG1555	photosystem II stabilization
A20_RS05670	COG1596	polysaccharide export
A20_RS05675	COG0204	Acyl-transferase
A20_RS05680	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
A20_RS05695	COG0513	Belongs to the DEAD box helicase family
A20_RS05710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A20_RS05725	COG0768	penicillin binding
A20_RS05730	COG2116	formate transmembrane transporter activity
A20_RS05740	COG1827	regulation of RNA biosynthetic process
A20_RS05755	COG2217	Heavy metal translocating P-type atpase
A20_RS05940	COG3723	Recombinational DNA repair protein, rece pathway
A20_RS05960	COG3935	DnaD domain protein
A20_RS05995	COG3561	AntA/AntB antirepressor
A20_RS06005	COG1396	sequence-specific DNA binding
A20_RS06020	COG0582	viral genome integration into host DNA
A20_RS06035	COG2755	lipolytic protein G-D-S-L family
A20_RS06050	COG0497	DNA recombination
A20_RS06055	COG1438	arginine binding
A20_RS06060	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A20_RS06085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A20_RS06090	COG0415	Belongs to the DNA photolyase family
A20_RS06100	COG0765	amino acid transport
A20_RS06105	COG4703	Protein of unknown function (DUF1797)
A20_RS06110	COG0542	response to heat
A20_RS06115	COG0494	nUDIX hydrolase
A20_RS06130	COG3599	regulation of cell shape
A20_RS06135	COG2302	S4 RNA-binding domain
A20_RS06150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A20_RS06185	COG1217	gtp-binding protein TYPA
A20_RS06190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A20_RS06195	COG1940	carbohydrate kinase activity
A20_RS06205	COG0783	Belongs to the Dps family
A20_RS06220	COG4470	Protein conserved in bacteria
A20_RS06230	COG3480	Lon protease (S16) C-terminal proteolytic domain
A20_RS06240	COG0742	ribosomal rna small subunit methyltransferase
A20_RS06250	COG0549	Belongs to the carbamate kinase family
A20_RS06255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A20_RS06260	COG1288	antiporter activity
A20_RS06275	COG2235	arginine
A20_RS06300	COG2972	Histidine kinase
A20_RS06315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A20_RS06320	COG0785	Cytochrome C biogenesis protein
A20_RS06325	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A20_RS06330	COG1518	maintenance of DNA repeat elements
A20_RS06390	COG1605	Chorismate mutase
A20_RS06390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A20_RS06410	COG2226	methyltransferase
A20_RS06420	COG3250	beta-galactosidase activity
A20_RS06425	COG4753	response regulator
A20_RS06425	COG2207	Transcriptional regulator
A20_RS06430	COG2972	Histidine kinase
A20_RS06440	COG1653	transport
A20_RS06445	COG0395	ABC-type sugar transport system, permease component
A20_RS06450	COG1175	transmembrane transport
A20_RS06455	COG1940	carbohydrate kinase activity
A20_RS06460	COG2723	6-phospho-beta-galactosidase activity
A20_RS06465	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A20_RS06480	COG0383	alpha-mannosidase activity
A20_RS06570	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A20_RS06575	COG1739	Uncharacterized protein family UPF0029
A20_RS06585	COG1098	S1 RNA binding domain
A20_RS06595	COG2197	response regulator
A20_RS06600	COG4585	Histidine kinase
A20_RS06610	COG0515	serine threonine protein kinase
A20_RS06610	COG2815	serine threonine protein kinase
A20_RS06620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A20_RS06620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A20_RS06630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A20_RS06650	COG0583	DNA-binding transcription factor activity
A20_RS06655	COG0183	Belongs to the thiolase family
A20_RS06660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A20_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
A20_RS06675	COG2610	gluconate transmembrane transporter activity
A20_RS06690	COG0116	Belongs to the methyltransferase superfamily
A20_RS06710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A20_RS06715	COG3579	cysteine-type endopeptidase activity
A20_RS06725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A20_RS06730	COG1113	amino acid transport
A20_RS06735	COG0492	ferredoxin-NADP+ reductase activity
A20_RS06745	COG1126	abc transporter atp-binding protein
A20_RS06755	COG0513	Belongs to the DEAD box helicase family
A20_RS06765	COG0768	penicillin binding
A20_RS06800	COG1131	(ABC) transporter
A20_RS06840	COG0446	pyridine nucleotide-disulphide oxidoreductase
A20_RS06845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A20_RS06880	COG1755	Isoprenylcysteine carboxyl methyltransferase
A20_RS06885	COG0656	L-ascorbic acid biosynthetic process
A20_RS06895	COG1283	sodium-dependent phosphate transmembrane transporter activity
A20_RS06915	COG0561	phosphatase activity
A20_RS06920	COG2860	membrane
A20_RS06970	COG2217	Heavy metal translocating P-type atpase
A20_RS07000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A20_RS07005	COG0195	Participates in both transcription termination and antitermination
A20_RS07025	COG1705	Flagellar rod assembly protein muramidase FlgJ
A20_RS07145	COG1783	phage Terminase large subunit
A20_RS07260	COG4974	Belongs to the 'phage' integrase family
A20_RS07280	COG4473	ABC transporter
A20_RS07285	COG1131	(ABC) transporter
A20_RS07290	COG0537	adenosine 5'-monophosphoramidase activity
A20_RS07300	COG1316	TRANSCRIPTIONal
A20_RS07310	COG0802	atpase or kinase
A20_RS07315	COG2252	PERMEase
A20_RS07320	COG0561	phosphatase activity
A20_RS07330	COG3715	PTS system
A20_RS07335	COG3716	PTS system mannose fructose sorbose family IID component
A20_RS07360	COG0439	Biotin carboxylase
A20_RS07375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A20_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
A20_RS07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A20_RS07410	COG1024	Enoyl-CoA hydratase
A20_RS07445	COG0588	phosphoglycerate mutase activity
A20_RS07450	COG2261	transglycosylase associated protein
A20_RS07475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A20_RS07475	COG0574	Belongs to the PEP-utilizing enzyme family
A20_RS07480	COG1335	isochorismatase
A20_RS07490	COG0436	Aminotransferase
A20_RS07500	COG0561	phosphatase activity
A20_RS07505	COG0252	asparaginase activity
A20_RS07520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A20_RS07525	COG1129	ABC transporter
A20_RS07540	COG1132	(ABC) transporter
A20_RS07545	COG4988	ABC transporter
A20_RS07550	COG1120	ATPase activity
A20_RS07575	COG1388	LysM domain
A20_RS07575	COG3942	CHAP domain
A20_RS07605	COG5433	transposase activity
A20_RS07610	COG1482	cell wall glycoprotein biosynthetic process
A20_RS07615	COG1940	carbohydrate kinase activity
A20_RS07625	COG2190	(PTS) system
A20_RS07625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A20_RS07625	COG1263	PTS System
A20_RS07630	COG1621	beta-fructofuranosidase activity
A20_RS07635	COG1609	Transcriptional regulator
A20_RS07655	COG2131	deaminase
A20_RS07660	COG0006	proline dipeptidase activity
A20_RS07700	COG1194	a g-specific adenine glycosylase
A20_RS07710	COG3118	belongs to the thioredoxin family
A20_RS07740	COG0681	Belongs to the peptidase S26 family
A20_RS07745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A20_RS07760	COG1882	Formate acetyltransferase
A20_RS07765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A20_RS07780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A20_RS07785	COG2814	Major facilitator Superfamily
A20_RS07790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A20_RS07815	COG0789	Transcriptional regulator
A20_RS07830	COG2081	HI0933 family
A20_RS07840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A20_RS07845	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A20_RS07865	COG0456	acetyltransferase
A20_RS07870	COG1214	PFAM Peptidase M22, glycoprotease
A20_RS07885	COG0174	glutamine synthetase
A20_RS07890	COG0789	Transcriptional regulator
A20_RS07905	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A20_RS07930	COG5433	transposase activity
A20_RS07970	COG0668	transmembrane transport
A20_RS07980	COG4720	Psort location CytoplasmicMembrane, score
A20_RS07985	COG0351	phosphomethylpyrimidine kinase
A20_RS08030	COG1929	Belongs to the glycerate kinase type-1 family
A20_RS08035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A20_RS08065	COG0577	efflux transmembrane transporter activity
A20_RS08070	COG1136	(ABC) transporter
A20_RS08095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A20_RS08095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A20_RS08100	COG1447	Phosphotransferase system cellobiose-specific component IIA
A20_RS08150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A20_RS08155	COG1476	TRANSCRIPTIONal
A20_RS08175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A20_RS08185	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A20_RS08200	COG1045	serine acetyltransferase
A20_RS08215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A20_RS08220	COG3037	sugar-specific permease SgaT UlaA
A20_RS08230	COG3711	transcriptional antiterminator
A20_RS08255	COG1846	Transcriptional regulator
A20_RS08275	COG4589	Belongs to the CDS family
A20_RS08285	COG1862	Preprotein translocase
A20_RS08295	COG1523	belongs to the glycosyl hydrolase 13 family
A20_RS08305	COG3842	ATPase activity
A20_RS08345	COG2190	(PTS) system
A20_RS08345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A20_RS08345	COG1263	PTS System
A20_RS08350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A20_RS08365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A20_RS08370	COG0512	Glutamine amidotransferase of anthranilate synthase
A20_RS08375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A20_RS08410	COG0601	transmembrane transport
A20_RS08420	COG1122	ATPase activity
A20_RS08440	COG0803	Belongs to the bacterial solute-binding protein 9 family
A20_RS08450	COG5433	transposase activity
A20_RS08480	COG3711	transcriptional antiterminator
A20_RS08490	COG1705	Flagellar rod assembly protein muramidase FlgJ
A20_RS08490	COG3942	CHAP domain
A20_RS08495	COG2205	protein histidine kinase activity
A20_RS08500	COG0745	RESPONSE REGULATOR receiver
A20_RS08505	COG0577	efflux transmembrane transporter activity
A20_RS08510	COG1136	(ABC) transporter
A20_RS08560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A20_RS08575	COG1882	Formate acetyltransferase
A20_RS08580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A20_RS08585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A20_RS08590	COG1447	Phosphotransferase system cellobiose-specific component IIA
A20_RS08595	COG2390	Transcriptional regulator
A20_RS08600	COG1349	DNA-binding transcription factor activity
A20_RS08605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A20_RS08620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A20_RS08635	COG0564	pseudouridine synthase activity
A20_RS08665	COG0542	response to heat
A20_RS08670	COG4463	regulation of RNA biosynthetic process
A20_RS08685	COG0450	alkyl hydroperoxide reductase
A20_RS08700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A20_RS08710	COG3404	Formiminotransferase-cyclodeaminase
A20_RS08725	COG0531	amino acid
A20_RS08755	COG3590	peptidase
A20_RS08760	COG0366	Alpha amylase catalytic
A20_RS08765	COG1263	PTS System
A20_RS08765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A20_RS08770	COG2188	Transcriptional regulator
A20_RS08780	COG2514	catechol 2,3-dioxygenase activity
A20_RS08790	COG0602	queuosine metabolic process
A20_RS08805	COG1328	CTP reductase activity
A20_RS08830	COG1393	Belongs to the ArsC family
A20_RS08845	COG0519	Catalyzes the synthesis of GMP from XMP
A20_RS08855	COG2814	Major facilitator Superfamily
A20_RS08890	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A20_RS08895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A20_RS08900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A20_RS08980	COG1511	domain protein
A20_RS09000	COG5433	transposase activity
A20_RS09010	COG0305	Participates in initiation and elongation during chromosome replication
A20_RS09040	COG1760	l-serine dehydratase
A20_RS09045	COG1760	l-serine dehydratase
A20_RS09050	COG0741	lytic transglycosylase activity
A20_RS09055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A20_RS09070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A20_RS09080	COG0612	Peptidase, M16
A20_RS09090	COG1215	transferase activity, transferring glycosyl groups
A20_RS09120	COG0516	GMP reductase activity
A20_RS09120	COG0517	IMP dehydrogenase activity
A20_RS09130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A20_RS09135	COG0488	(ABC) transporter
A20_RS09175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A20_RS09180	COG1475	DNA binding
A20_RS09190	COG3328	transposase activity