locus-tag	class	description
DB248_RS00010	COG0592	DNA-directed DNA polymerase activity
DB248_RS00020	COG0012	GTP binding
DB248_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DB248_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DB248_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DB248_RS00065	COG0531	amino acid
DB248_RS00245	COG3942	CHAP domain
DB248_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DB248_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DB248_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DB248_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DB248_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DB248_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DB248_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
DB248_RS00355	COG1454	alcohol dehydrogenase
DB248_RS00360	COG1064	alcohol dehydrogenase
DB248_RS00365	COG0534	Mate efflux family protein
DB248_RS00475	COG0201	protein transport
DB248_RS00620	COG1121	(ABC) transporter
DB248_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DB248_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB248_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DB248_RS00665	COG1459	type II secretion system
DB248_RS00670	COG4537	Required for transformation and DNA binding
DB248_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DB248_RS00715	COG1363	Peptidase, m42
DB248_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB248_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DB248_RS00745	COG1428	Deoxynucleoside kinase
DB248_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DB248_RS00785	COG4509	Sortase family
DB248_RS00795	COG4372	Transposase
DB248_RS00825	COG2031	fatty acid transporter
DB248_RS00840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DB248_RS00855	COG0251	oxidation-reduction process
DB248_RS00870	COG1269	ATP hydrolysis coupled proton transport
DB248_RS00875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DB248_RS00885	COG1527	subunit (C
DB248_RS00890	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
DB248_RS00925	COG1744	ABC transporter substrate-binding protein PnrA-like
DB248_RS00970	COG0626	cystathionine gamma-synthase activity
DB248_RS01000	COG3623	hexulose-6-phosphate isomerase
DB248_RS01025	COG4175	Glycine betaine
DB248_RS01025	COG3448	diguanylate cyclase activity
DB248_RS01035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB248_RS01035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DB248_RS01055	COG3969	phosphoadenosine phosphosulfate
DB248_RS01060	COG1475	DNA binding
DB248_RS01085	COG0157	Belongs to the NadC ModD family
DB248_RS01110	COG1268	BioY protein
DB248_RS01115	COG1234	tRNA 3'-trailer cleavage
DB248_RS01150	COG5433	transposase activity
DB248_RS01160	COG0705	Rhomboid family
DB248_RS01160	COG0457	Tetratricopeptide repeat
DB248_RS01180	COG1132	(ABC) transporter
DB248_RS01185	COG1132	(ABC) transporter
DB248_RS01195	COG0756	dUTP diphosphatase activity
DB248_RS01220	COG3290	protein histidine kinase activity
DB248_RS01245	COG1847	R3H domain protein
DB248_RS01265	COG1175	transmembrane transport
DB248_RS01270	COG0395	ABC-type sugar transport system, permease component
DB248_RS01280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DB248_RS01295	COG0084	hydrolase, TatD family'
DB248_RS01320	COG1564	THIamine pyrophosphokinase
DB248_RS01335	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DB248_RS01375	COG0765	amino acid transport
DB248_RS01395	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DB248_RS01405	COG0719	Fe-S assembly protein
DB248_RS01410	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DB248_RS01425	COG1686	Belongs to the peptidase S11 family
DB248_RS01430	COG1686	Belongs to the peptidase S11 family
DB248_RS01435	COG4166	transmembrane transport
DB248_RS01440	COG0601	transmembrane transport
DB248_RS01445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DB248_RS01450	COG0444	Belongs to the ABC transporter superfamily
DB248_RS01460	COG2801	Transposase and inactivated derivatives
DB248_RS01510	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DB248_RS01515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DB248_RS01520	COG1534	Rna-binding protein
DB248_RS01530	COG1713	HD superfamily hydrolase involved in NAD metabolism
DB248_RS01535	COG0799	negative regulation of ribosome biogenesis
DB248_RS01540	COG2226	methyltransferase
DB248_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB248_RS01565	COG1464	Belongs to the NlpA lipoprotein family
DB248_RS01580	COG1114	Component of the transport system for branched-chain amino acids
DB248_RS01590	COG0569	domain protein
DB248_RS01595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DB248_RS01605	COG1704	LemA family
DB248_RS01620	COG0745	RESPONSE REGULATOR receiver
DB248_RS01640	COG1484	DNA-dependent DNA replication
DB248_RS01650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DB248_RS01670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DB248_RS01685	COG1254	Belongs to the acylphosphatase family
DB248_RS01700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DB248_RS01755	COG1187	pseudouridine synthase activity
DB248_RS01770	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DB248_RS01775	COG0671	phosphoesterase, PA-phosphatase related
DB248_RS01780	COG1242	4 iron, 4 sulfur cluster binding
DB248_RS01785	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DB248_RS01790	COG1253	flavin adenine dinucleotide binding
DB248_RS01795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DB248_RS01810	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB248_RS01815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DB248_RS01820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DB248_RS01825	COG1120	ATPase activity
DB248_RS01835	COG2244	polysaccharide biosynthetic process
DB248_RS01870	COG0470	DNA polymerase III
DB248_RS01900	COG1393	Belongs to the ArsC family
DB248_RS01905	COG0708	Exodeoxyribonuclease III
DB248_RS01915	COG1304	FMN binding
DB248_RS02005	COG1028	Short-chain dehydrogenase reductase Sdr
DB248_RS02010	COG0673	inositol 2-dehydrogenase activity
DB248_RS02025	COG0494	nUDIX hydrolase
DB248_RS02035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DB248_RS02125	COG1702	phosphate starvation-inducible protein PhoH
DB248_RS02130	COG1573	uracil-dna glycosylase
DB248_RS02140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DB248_RS02230	COG0433	COG0433 Predicted ATPase
DB248_RS02235	COG2814	Major facilitator Superfamily
DB248_RS02250	COG0557	exoribonuclease II activity
DB248_RS02280	COG0463	Glycosyl transferase, family 2
DB248_RS02290	COG0778	Nitroreductase
DB248_RS02295	COG0006	proline dipeptidase activity
DB248_RS02300	COG1609	Transcriptional regulator
DB248_RS02310	COG0438	transferase activity, transferring glycosyl groups
DB248_RS02320	COG4555	ABC transporter
DB248_RS02335	COG0183	Belongs to the thiolase family
DB248_RS02350	COG0745	RESPONSE REGULATOR receiver
DB248_RS02355	COG5002	protein histidine kinase activity
DB248_RS02360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DB248_RS02370	COG1196	nuclear chromosome segregation
DB248_RS02380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DB248_RS02470	COG4695	Portal protein
DB248_RS02515	COG0561	phosphatase activity
DB248_RS02520	COG0561	phosphatase activity
DB248_RS02525	COG0552	protein localization to endoplasmic reticulum
DB248_RS02530	COG0477	Major facilitator Superfamily
DB248_RS02535	COG3711	transcriptional antiterminator
DB248_RS02540	COG1263	PTS System
DB248_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB248_RS02540	COG2190	(PTS) system
DB248_RS02550	COG3689	TIGRFAM TIGR03943 family protein
DB248_RS02555	COG0701	Predicted permease
DB248_RS02565	COG2183	response to ionizing radiation
DB248_RS02610	COG0826	peptidase U32
DB248_RS02615	COG4443	Transcriptional Coactivator p15 (PC4)
DB248_RS02660	COG0386	Belongs to the glutathione peroxidase family
DB248_RS02665	COG1164	Oligoendopeptidase f
DB248_RS02675	COG0772	Belongs to the SEDS family
DB248_RS02710	COG1078	dGTPase activity
DB248_RS02725	COG1609	Transcriptional regulator
DB248_RS02735	COG3716	PTS system mannose fructose sorbose family IID component
DB248_RS02740	COG3715	PTS system
DB248_RS02745	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB248_RS02760	COG1028	Short-chain dehydrogenase reductase Sdr
DB248_RS02775	COG0800	Aldolase
DB248_RS02780	COG0546	phosphoglycolate phosphatase activity
DB248_RS02785	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DB248_RS02795	COG2884	Cell division ATP-binding protein ftsE
DB248_RS02800	COG2177	Part of the ABC transporter FtsEX involved in
DB248_RS02820	COG1199	ATP-dependent helicase activity
DB248_RS02820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DB248_RS02825	COG0436	Aminotransferase
DB248_RS02860	COG3620	sequence-specific DNA binding
DB248_RS02930	COG3723	Recombinational DNA repair protein, rece pathway
DB248_RS03000	COG1598	PFAM Uncharacterised protein family UPF0150
DB248_RS03045	COG0740	serine-type endopeptidase activity
DB248_RS03130	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB248_RS03130	COG1388	LysM domain
DB248_RS03170	COG2188	Transcriptional regulator
DB248_RS03175	COG2222	sugar isomerase
DB248_RS03185	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DB248_RS03190	COG0716	FMN binding
DB248_RS03200	COG0038	chloride channel
DB248_RS03295	COG1131	(ABC) transporter
DB248_RS03320	COG4708	membrane
DB248_RS03330	COG1597	lipid kinase activity
DB248_RS03415	COG0577	efflux transmembrane transporter activity
DB248_RS03425	COG2321	neutral zinc metallopeptidase
DB248_RS03440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB248_RS03450	COG1970	mechanosensitive ion channel activity
DB248_RS03455	COG0358	DNA primase activity
DB248_RS03460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DB248_RS03465	COG2151	metal-sulfur cluster biosynthetic enzyme
DB248_RS03510	COG1216	Glycosyl transferase, family 2
DB248_RS03570	COG1368	sulfuric ester hydrolase activity
DB248_RS03575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DB248_RS03595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DB248_RS03600	COG0285	dihydrofolate synthase activity
DB248_RS03610	COG1104	cysteine desulfurase activity
DB248_RS03635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DB248_RS03645	COG0583	DNA-binding transcription factor activity
DB248_RS03655	COG0564	pseudouridine synthase activity
DB248_RS03685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DB248_RS03690	COG1136	(ABC) transporter
DB248_RS03695	COG0577	efflux transmembrane transporter activity
DB248_RS03700	COG0584	glycerophosphoryl diester phosphodiesterase
DB248_RS03710	COG1837	Belongs to the UPF0109 family
DB248_RS03760	COG1349	DNA-binding transcription factor activity
DB248_RS03765	COG1105	Belongs to the carbohydrate kinase PfkB family
DB248_RS03770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB248_RS03770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB248_RS03770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DB248_RS03775	COG1388	LysM domain
DB248_RS03775	COG1705	Flagellar rod assembly protein muramidase FlgJ
DB248_RS03780	COG1705	Flagellar rod assembly protein muramidase FlgJ
DB248_RS03780	COG1388	LysM domain
DB248_RS03800	COG0105	UTP biosynthetic process
DB248_RS03820	COG0488	(ABC) transporter
DB248_RS03830	COG0242	peptide deformylase activity
DB248_RS03835	COG0737	Belongs to the 5'-nucleotidase family
DB248_RS03840	COG2357	RelA SpoT domain protein
DB248_RS03845	COG0745	RESPONSE REGULATOR receiver
DB248_RS03880	COG3425	synthase
DB248_RS03890	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DB248_RS03950	COG0583	DNA-binding transcription factor activity
DB248_RS03975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB248_RS03980	COG0765	amino acid transport
DB248_RS04000	COG0187	DNA topoisomerase II activity
DB248_RS04010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DB248_RS04030	COG0539	negative regulation of cytoplasmic translation
DB248_RS04075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DB248_RS04080	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DB248_RS04090	COG0300	oxidoreductase activity
DB248_RS04095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DB248_RS04095	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DB248_RS04110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DB248_RS04115	COG2384	SAM-dependent methyltransferase
DB248_RS04125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DB248_RS04130	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DB248_RS04140	COG1088	dTDP-glucose 4,6-dehydratase activity
DB248_RS04145	COG1051	belongs to the nudix hydrolase family
DB248_RS04150	COG0628	permease
DB248_RS04155	COG0457	Tetratricopeptide repeat
DB248_RS04160	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DB248_RS04180	COG1129	ABC transporter
DB248_RS04200	COG0488	(ABC) transporter
DB248_RS04205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DB248_RS04210	COG0508	dehydrogenase complex catalyzes the overall conversion of
DB248_RS04210	COG0022	dehydrogenase e1 component
DB248_RS04240	COG5492	domain, Protein
DB248_RS04245	COG0095	Lipoate-protein ligase
DB248_RS04250	COG3442	glutamine amidotransferase
DB248_RS04255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DB248_RS04260	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DB248_RS04280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DB248_RS04290	COG0647	UMP catabolic process
DB248_RS04310	COG1518	maintenance of DNA repeat elements
DB248_RS04315	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DB248_RS04375	COG0305	Participates in initiation and elongation during chromosome replication
DB248_RS04440	COG0582	viral genome integration into host DNA
DB248_RS04485	COG0740	serine-type endopeptidase activity
DB248_RS04570	COG1705	Flagellar rod assembly protein muramidase FlgJ
DB248_RS04605	COG0105	UTP biosynthetic process
DB248_RS04640	COG3715	PTS system
DB248_RS04645	COG3716	PTS system mannose fructose sorbose family IID component
DB248_RS04650	COG2972	Histidine kinase
DB248_RS04655	COG2207	Transcriptional regulator
DB248_RS04655	COG4753	response regulator
DB248_RS04660	COG1840	ABC-type Fe3 transport system, periplasmic component
DB248_RS04675	COG1011	Hydrolase
DB248_RS04680	COG1012	belongs to the aldehyde dehydrogenase family
DB248_RS04695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB248_RS04760	COG1131	(ABC) transporter
DB248_RS04775	COG1396	sequence-specific DNA binding
DB248_RS04805	COG0285	dihydrofolate synthase activity
DB248_RS04825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DB248_RS04840	COG1176	ABC-type spermidine putrescine transport system, permease component I
DB248_RS04845	COG1177	transmembrane transport
DB248_RS04855	COG4565	transcriptional regulatory protein
DB248_RS04860	COG3290	protein histidine kinase activity
DB248_RS04865	COG3493	citrate carrier protein
DB248_RS04880	COG3700	Belongs to the class B bacterial acid phosphatase family
DB248_RS04885	COG0038	chloride channel
DB248_RS04895	COG0628	permease
DB248_RS04905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DB248_RS04920	COG1104	cysteine desulfurase activity
DB248_RS04935	COG2357	RelA SpoT domain protein
DB248_RS04945	COG0564	pseudouridine synthase activity
DB248_RS04950	COG0280	phosphate acetyltransferase
DB248_RS04970	COG1174	glycine betaine transport
DB248_RS04990	COG2233	PERMEase
DB248_RS05015	COG2890	protein-(glutamine-N5) methyltransferase activity
DB248_RS05045	COG1132	(ABC) transporter
DB248_RS05050	COG1132	(ABC) transporter
DB248_RS05070	COG3764	Sortase (surface protein transpeptidase)
DB248_RS05075	COG0346	lactoylglutathione lyase activity
DB248_RS05095	COG1272	protein, Hemolysin III
DB248_RS05115	COG0758	DNA mediated transformation
DB248_RS05120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DB248_RS05170	COG0511	ligase activity, forming carbon-carbon bonds
DB248_RS05175	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DB248_RS05190	COG2851	Citrate transporter
DB248_RS05200	COG0511	ligase activity, forming carbon-carbon bonds
DB248_RS05205	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DB248_RS05235	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DB248_RS05255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DB248_RS05265	COG2188	Transcriptional regulator
DB248_RS05285	COG0488	(ABC) transporter
DB248_RS05295	COG0352	thiamine-phosphate diphosphorylase activity
DB248_RS05295	COG0351	phosphomethylpyrimidine kinase
DB248_RS05300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DB248_RS05310	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DB248_RS05310	COG1328	CTP reductase activity
DB248_RS05315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DB248_RS05345	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DB248_RS05365	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DB248_RS05370	COG4684	Psort location CytoplasmicMembrane, score
DB248_RS05375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DB248_RS05380	COG1079	Belongs to the binding-protein-dependent transport system permease family
DB248_RS05385	COG4603	Belongs to the binding-protein-dependent transport system permease family
DB248_RS05390	COG3845	ABC transporter
DB248_RS05395	COG1744	ABC transporter substrate-binding protein PnrA-like
DB248_RS05400	COG0295	cytidine deaminase activity
DB248_RS05405	COG2813	Specifically methylates the guanine in position
DB248_RS05420	COG5002	protein histidine kinase activity
DB248_RS05425	COG0745	RESPONSE REGULATOR receiver
DB248_RS05440	COG0704	Plays a role in the regulation of phosphate uptake
DB248_RS05455	COG0581	inorganic phosphate transmembrane transporter activity
DB248_RS05460	COG0573	inorganic phosphate transmembrane transporter activity
DB248_RS05470	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DB248_RS05470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DB248_RS05475	COG0483	inositol monophosphate 1-phosphatase activity
DB248_RS05490	COG0196	riboflavin kinase activity
DB248_RS05520	COG1136	(ABC) transporter
DB248_RS05520	COG4591	ABC-type transport system involved in lipoprotein release permease component
DB248_RS05570	COG1115	amino acid carrier protein
DB248_RS05575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DB248_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB248_RS05590	COG1126	abc transporter atp-binding protein
DB248_RS05595	COG0765	amino acid transport
DB248_RS05600	COG2824	Alkylphosphonate utilization operon protein PhnA
DB248_RS05615	COG0469	pyruvate kinase activity
DB248_RS05630	COG1725	Transcriptional regulator
DB248_RS05635	COG1131	(ABC) transporter
DB248_RS05790	COG1783	phage Terminase large subunit
DB248_RS05910	COG1396	sequence-specific DNA binding
DB248_RS05955	COG0058	SHG alpha-glucan phosphorylase activity
DB248_RS05960	COG1640	4-alpha-glucanotransferase
DB248_RS05965	COG1609	Transcriptional regulator
DB248_RS05970	COG2182	Extracellular solute-binding protein
DB248_RS05975	COG1175	transmembrane transport
DB248_RS05980	COG3833	ABC-type maltose transport systems, permease component
DB248_RS05995	COG3833	ABC-type maltose transport systems, permease component
DB248_RS06000	COG1175	transmembrane transport
DB248_RS06010	COG0366	Alpha amylase catalytic
DB248_RS06015	COG2182	Extracellular solute-binding protein
DB248_RS06025	COG0657	acetylesterase activity
DB248_RS06030	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DB248_RS06040	COG1696	Membrane protein involved in D-alanine export
DB248_RS06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DB248_RS06065	COG1126	abc transporter atp-binding protein
DB248_RS06070	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB248_RS06080	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB248_RS06090	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DB248_RS06090	COG3711	transcriptional antiterminator
DB248_RS06100	COG2723	6-phospho-beta-galactosidase activity
DB248_RS06130	COG1187	pseudouridine synthase activity
DB248_RS06140	COG2814	Major facilitator Superfamily
DB248_RS06190	COG4109	DRTGG domain
DB248_RS06195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DB248_RS06220	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DB248_RS06220	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DB248_RS06230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DB248_RS06235	COG1956	GAF domain-containing protein
DB248_RS06255	COG0513	Belongs to the DEAD box helicase family
DB248_RS06260	COG0726	polysaccharide deacetylase
DB248_RS06280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DB248_RS06285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB248_RS06290	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DB248_RS06320	COG1476	TRANSCRIPTIONal
DB248_RS06335	COG4122	O-methyltransferase activity
DB248_RS06340	COG2223	nitrite transmembrane transporter activity
DB248_RS06355	COG1187	pseudouridine synthase activity
DB248_RS06400	COG2333	competence protein COMEC
DB248_RS06400	COG0658	competence protein
DB248_RS06405	COG1596	polysaccharide export
DB248_RS06405	COG1555	photosystem II stabilization
DB248_RS06410	COG0204	Acyl-transferase
DB248_RS06415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DB248_RS06430	COG0513	Belongs to the DEAD box helicase family
DB248_RS06450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DB248_RS06465	COG0768	penicillin binding
DB248_RS06470	COG2116	formate transmembrane transporter activity
DB248_RS06480	COG1827	regulation of RNA biosynthetic process
DB248_RS06495	COG2217	Heavy metal translocating P-type atpase
DB248_RS06685	COG3723	Recombinational DNA repair protein, rece pathway
DB248_RS06735	COG1396	sequence-specific DNA binding
DB248_RS06745	COG0582	viral genome integration into host DNA
DB248_RS06760	COG2755	lipolytic protein G-D-S-L family
DB248_RS06775	COG0497	DNA recombination
DB248_RS06780	COG1438	arginine binding
DB248_RS06785	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DB248_RS06810	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DB248_RS06815	COG0415	Belongs to the DNA photolyase family
DB248_RS06825	COG0765	amino acid transport
DB248_RS06830	COG4703	Protein of unknown function (DUF1797)
DB248_RS06835	COG0542	response to heat
DB248_RS06840	COG0494	nUDIX hydrolase
DB248_RS06855	COG3599	regulation of cell shape
DB248_RS06860	COG2302	S4 RNA-binding domain
DB248_RS06875	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DB248_RS06910	COG1217	gtp-binding protein TYPA
DB248_RS06915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DB248_RS06920	COG1940	carbohydrate kinase activity
DB248_RS06930	COG0783	Belongs to the Dps family
DB248_RS06945	COG4470	Protein conserved in bacteria
DB248_RS06950	COG1609	Transcriptional regulator
DB248_RS06955	COG3480	Lon protease (S16) C-terminal proteolytic domain
DB248_RS06965	COG0742	ribosomal rna small subunit methyltransferase
DB248_RS06975	COG0549	Belongs to the carbamate kinase family
DB248_RS06980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DB248_RS06985	COG1288	antiporter activity
DB248_RS07000	COG2235	arginine
DB248_RS07025	COG2972	Histidine kinase
DB248_RS07040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DB248_RS07045	COG0785	Cytochrome C biogenesis protein
DB248_RS07050	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DB248_RS07055	COG1518	maintenance of DNA repeat elements
DB248_RS07120	COG1605	Chorismate mutase
DB248_RS07120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DB248_RS07140	COG2226	methyltransferase
DB248_RS07150	COG3250	beta-galactosidase activity
DB248_RS07155	COG4753	response regulator
DB248_RS07155	COG2207	Transcriptional regulator
DB248_RS07160	COG2972	Histidine kinase
DB248_RS07170	COG1653	transport
DB248_RS07175	COG0395	ABC-type sugar transport system, permease component
DB248_RS07180	COG1175	transmembrane transport
DB248_RS07185	COG1940	carbohydrate kinase activity
DB248_RS07190	COG2723	6-phospho-beta-galactosidase activity
DB248_RS07195	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DB248_RS07210	COG0383	alpha-mannosidase activity
DB248_RS07250	COG1388	LysM domain
DB248_RS07250	COG0860	N-Acetylmuramoyl-L-alanine amidase
DB248_RS07255	COG4824	toxin secretion phage lysis holin
DB248_RS07485	COG3561	AntA/AntB antirepressor
DB248_RS07605	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DB248_RS07610	COG1739	Uncharacterized protein family UPF0029
DB248_RS07620	COG1098	S1 RNA binding domain
DB248_RS07630	COG2197	response regulator
DB248_RS07635	COG4585	Histidine kinase
DB248_RS07645	COG0515	serine threonine protein kinase
DB248_RS07645	COG2815	serine threonine protein kinase
DB248_RS07655	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DB248_RS07655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DB248_RS07665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DB248_RS07685	COG0583	DNA-binding transcription factor activity
DB248_RS07690	COG0183	Belongs to the thiolase family
DB248_RS07695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DB248_RS07705	COG1028	Short-chain dehydrogenase reductase Sdr
DB248_RS07710	COG2610	gluconate transmembrane transporter activity
DB248_RS07725	COG0116	Belongs to the methyltransferase superfamily
DB248_RS07750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB248_RS07755	COG3579	cysteine-type endopeptidase activity
DB248_RS07765	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DB248_RS07770	COG1113	amino acid transport
DB248_RS07775	COG0492	ferredoxin-NADP+ reductase activity
DB248_RS07785	COG1126	abc transporter atp-binding protein
DB248_RS07795	COG0513	Belongs to the DEAD box helicase family
DB248_RS07805	COG0768	penicillin binding
DB248_RS07845	COG1131	(ABC) transporter
DB248_RS07870	COG0446	pyridine nucleotide-disulphide oxidoreductase
DB248_RS07875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DB248_RS07915	COG1755	Isoprenylcysteine carboxyl methyltransferase
DB248_RS07920	COG0656	L-ascorbic acid biosynthetic process
DB248_RS07930	COG1283	sodium-dependent phosphate transmembrane transporter activity
DB248_RS07950	COG0561	phosphatase activity
DB248_RS07955	COG2860	membrane
DB248_RS08010	COG2217	Heavy metal translocating P-type atpase
DB248_RS08040	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DB248_RS08045	COG0195	Participates in both transcription termination and antitermination
DB248_RS08070	COG4473	ABC transporter
DB248_RS08075	COG1131	(ABC) transporter
DB248_RS08080	COG0537	adenosine 5'-monophosphoramidase activity
DB248_RS08090	COG1316	TRANSCRIPTIONal
DB248_RS08100	COG0802	atpase or kinase
DB248_RS08105	COG2252	PERMEase
DB248_RS08110	COG0561	phosphatase activity
DB248_RS08120	COG3715	PTS system
DB248_RS08125	COG3716	PTS system mannose fructose sorbose family IID component
DB248_RS08150	COG0439	Biotin carboxylase
DB248_RS08165	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DB248_RS08170	COG1028	Short-chain dehydrogenase reductase Sdr
DB248_RS08175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DB248_RS08200	COG1024	Enoyl-CoA hydratase
DB248_RS08235	COG0588	phosphoglycerate mutase activity
DB248_RS08240	COG2261	transglycosylase associated protein
DB248_RS08275	COG1335	isochorismatase
DB248_RS08285	COG0436	Aminotransferase
DB248_RS08295	COG0561	phosphatase activity
DB248_RS08300	COG0252	asparaginase activity
DB248_RS08315	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DB248_RS08325	COG1129	ABC transporter
DB248_RS08340	COG1132	(ABC) transporter
DB248_RS08345	COG4988	ABC transporter
DB248_RS08350	COG1120	ATPase activity
DB248_RS08375	COG1388	LysM domain
DB248_RS08375	COG3942	CHAP domain
DB248_RS08405	COG1482	cell wall glycoprotein biosynthetic process
DB248_RS08410	COG1940	carbohydrate kinase activity
DB248_RS08420	COG1263	PTS System
DB248_RS08420	COG2190	(PTS) system
DB248_RS08420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB248_RS08425	COG1621	beta-fructofuranosidase activity
DB248_RS08430	COG1609	Transcriptional regulator
DB248_RS08450	COG2131	deaminase
DB248_RS08455	COG0006	proline dipeptidase activity
DB248_RS08495	COG1194	a g-specific adenine glycosylase
DB248_RS08505	COG3118	belongs to the thioredoxin family
DB248_RS08535	COG0681	Belongs to the peptidase S26 family
DB248_RS08540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DB248_RS08555	COG1882	Formate acetyltransferase
DB248_RS08560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DB248_RS08575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DB248_RS08585	COG2814	Major facilitator Superfamily
DB248_RS08590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DB248_RS08615	COG0789	Transcriptional regulator
DB248_RS08630	COG2081	HI0933 family
DB248_RS08640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DB248_RS08645	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DB248_RS08665	COG0456	acetyltransferase
DB248_RS08670	COG1214	PFAM Peptidase M22, glycoprotease
DB248_RS08685	COG0174	glutamine synthetase
DB248_RS08690	COG0789	Transcriptional regulator
DB248_RS08705	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DB248_RS08760	COG0668	transmembrane transport
DB248_RS08770	COG4720	Psort location CytoplasmicMembrane, score
DB248_RS08775	COG0351	phosphomethylpyrimidine kinase
DB248_RS08820	COG1929	Belongs to the glycerate kinase type-1 family
DB248_RS08825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DB248_RS08855	COG0577	efflux transmembrane transporter activity
DB248_RS08860	COG1136	(ABC) transporter
DB248_RS08865	COG2274	protein secretion by the type I secretion system
DB248_RS08885	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB248_RS08885	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB248_RS08890	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB248_RS08940	COG4974	Belongs to the 'phage' integrase family
DB248_RS08950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DB248_RS08955	COG1476	TRANSCRIPTIONal
DB248_RS08975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DB248_RS08985	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DB248_RS09005	COG1045	serine acetyltransferase
DB248_RS09020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DB248_RS09030	COG3037	sugar-specific permease SgaT UlaA
DB248_RS09040	COG3711	transcriptional antiterminator
DB248_RS09070	COG1846	Transcriptional regulator
DB248_RS09090	COG4589	Belongs to the CDS family
DB248_RS09100	COG1862	Preprotein translocase
DB248_RS09110	COG1523	belongs to the glycosyl hydrolase 13 family
DB248_RS09125	COG3842	ATPase activity
DB248_RS09165	COG2190	(PTS) system
DB248_RS09165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB248_RS09165	COG1263	PTS System
DB248_RS09170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DB248_RS09185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DB248_RS09190	COG0512	Glutamine amidotransferase of anthranilate synthase
DB248_RS09195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DB248_RS09235	COG0601	transmembrane transport
DB248_RS09245	COG1122	ATPase activity
DB248_RS09265	COG0803	Belongs to the bacterial solute-binding protein 9 family
DB248_RS09300	COG3711	transcriptional antiterminator
DB248_RS09315	COG1705	Flagellar rod assembly protein muramidase FlgJ
DB248_RS09315	COG3942	CHAP domain
DB248_RS09320	COG2205	protein histidine kinase activity
DB248_RS09325	COG0745	RESPONSE REGULATOR receiver
DB248_RS09330	COG0577	efflux transmembrane transporter activity
DB248_RS09335	COG1136	(ABC) transporter
DB248_RS09400	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DB248_RS09415	COG1882	Formate acetyltransferase
DB248_RS09420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB248_RS09425	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DB248_RS09430	COG1447	Phosphotransferase system cellobiose-specific component IIA
DB248_RS09435	COG2390	Transcriptional regulator
DB248_RS09440	COG1349	DNA-binding transcription factor activity
DB248_RS09445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DB248_RS09465	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DB248_RS09480	COG0564	pseudouridine synthase activity
DB248_RS09515	COG0542	response to heat
DB248_RS09520	COG4463	regulation of RNA biosynthetic process
DB248_RS09535	COG0450	alkyl hydroperoxide reductase
DB248_RS09550	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DB248_RS09560	COG3404	Formiminotransferase-cyclodeaminase
DB248_RS09575	COG0531	amino acid
DB248_RS09605	COG3590	peptidase
DB248_RS09610	COG0366	Alpha amylase catalytic
DB248_RS09615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DB248_RS09615	COG1263	PTS System
DB248_RS09620	COG2188	Transcriptional regulator
DB248_RS09630	COG1733	regulation of RNA biosynthetic process
DB248_RS09635	COG2514	catechol 2,3-dioxygenase activity
DB248_RS09645	COG0602	queuosine metabolic process
DB248_RS09660	COG1328	CTP reductase activity
DB248_RS09685	COG1393	Belongs to the ArsC family
DB248_RS09700	COG0519	Catalyzes the synthesis of GMP from XMP
DB248_RS09710	COG2814	Major facilitator Superfamily
DB248_RS09745	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB248_RS09750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB248_RS09755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB248_RS09840	COG1511	domain protein
DB248_RS09860	COG5433	transposase activity
DB248_RS09870	COG0305	Participates in initiation and elongation during chromosome replication
DB248_RS09900	COG1760	l-serine dehydratase
DB248_RS09905	COG1760	l-serine dehydratase
DB248_RS09910	COG0741	lytic transglycosylase activity
DB248_RS09915	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DB248_RS09930	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DB248_RS09940	COG0612	Peptidase, M16
DB248_RS09950	COG1215	transferase activity, transferring glycosyl groups
DB248_RS09985	COG0517	IMP dehydrogenase activity
DB248_RS09985	COG0516	GMP reductase activity
DB248_RS09995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DB248_RS10000	COG0488	(ABC) transporter
DB248_RS10040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DB248_RS10045	COG1475	DNA binding