locus-tag	class	description
B2G65_RS00010	COG0592	DNA-directed DNA polymerase activity
B2G65_RS00020	COG0012	GTP binding
B2G65_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B2G65_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B2G65_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B2G65_RS00065	COG0531	amino acid
B2G65_RS00240	COG3942	CHAP domain
B2G65_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B2G65_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B2G65_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B2G65_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B2G65_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B2G65_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B2G65_RS00350	COG1454	alcohol dehydrogenase
B2G65_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
B2G65_RS00355	COG1064	alcohol dehydrogenase
B2G65_RS00360	COG0534	Mate efflux family protein
B2G65_RS00470	COG0201	protein transport
B2G65_RS00615	COG1121	(ABC) transporter
B2G65_RS00620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B2G65_RS00635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2G65_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B2G65_RS00660	COG1459	type II secretion system
B2G65_RS00665	COG4537	Required for transformation and DNA binding
B2G65_RS00705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B2G65_RS00710	COG1363	Peptidase, m42
B2G65_RS00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2G65_RS00730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B2G65_RS00740	COG1428	Deoxynucleoside kinase
B2G65_RS00745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B2G65_RS00775	COG4509	Sortase family
B2G65_RS00800	COG2031	fatty acid transporter
B2G65_RS00815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B2G65_RS00830	COG0251	oxidation-reduction process
B2G65_RS00845	COG1269	ATP hydrolysis coupled proton transport
B2G65_RS00850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B2G65_RS00860	COG1527	subunit (C
B2G65_RS00865	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
B2G65_RS00900	COG1744	ABC transporter substrate-binding protein PnrA-like
B2G65_RS00940	COG0626	cystathionine gamma-synthase activity
B2G65_RS00970	COG3623	hexulose-6-phosphate isomerase
B2G65_RS00995	COG4175	Glycine betaine
B2G65_RS00995	COG3448	diguanylate cyclase activity
B2G65_RS01005	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2G65_RS01005	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B2G65_RS01040	COG1268	BioY protein
B2G65_RS01045	COG1234	tRNA 3'-trailer cleavage
B2G65_RS01080	COG0457	Tetratricopeptide repeat
B2G65_RS01080	COG0705	Rhomboid family
B2G65_RS01100	COG1132	(ABC) transporter
B2G65_RS01105	COG1132	(ABC) transporter
B2G65_RS01115	COG0756	dUTP diphosphatase activity
B2G65_RS01140	COG3290	protein histidine kinase activity
B2G65_RS01165	COG1847	R3H domain protein
B2G65_RS01185	COG1175	transmembrane transport
B2G65_RS01190	COG0395	ABC-type sugar transport system, permease component
B2G65_RS01200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B2G65_RS01215	COG0084	hydrolase, TatD family'
B2G65_RS01240	COG1564	THIamine pyrophosphokinase
B2G65_RS01255	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B2G65_RS01280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B2G65_RS01295	COG0765	amino acid transport
B2G65_RS01315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B2G65_RS01325	COG0719	Fe-S assembly protein
B2G65_RS01330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B2G65_RS01345	COG1686	Belongs to the peptidase S11 family
B2G65_RS01350	COG1686	Belongs to the peptidase S11 family
B2G65_RS01355	COG4166	transmembrane transport
B2G65_RS01360	COG0601	transmembrane transport
B2G65_RS01365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B2G65_RS01370	COG0444	Belongs to the ABC transporter superfamily
B2G65_RS01425	COG0351	phosphomethylpyrimidine kinase
B2G65_RS01430	COG4720	Psort location CytoplasmicMembrane, score
B2G65_RS01440	COG0668	transmembrane transport
B2G65_RS01495	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B2G65_RS01510	COG0789	Transcriptional regulator
B2G65_RS01515	COG0174	glutamine synthetase
B2G65_RS01530	COG1214	PFAM Peptidase M22, glycoprotease
B2G65_RS01535	COG0456	acetyltransferase
B2G65_RS01555	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B2G65_RS01560	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B2G65_RS01570	COG2081	HI0933 family
B2G65_RS01585	COG0789	Transcriptional regulator
B2G65_RS01595	COG0582	viral genome integration into host DNA
B2G65_RS01635	COG3561	AntA/AntB antirepressor
B2G65_RS01885	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS01895	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2G65_RS01895	COG1388	LysM domain
B2G65_RS01940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B2G65_RS01945	COG2814	Major facilitator Superfamily
B2G65_RS01955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B2G65_RS01970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B2G65_RS01975	COG1882	Formate acetyltransferase
B2G65_RS01990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B2G65_RS01995	COG0681	Belongs to the peptidase S26 family
B2G65_RS02025	COG3118	belongs to the thioredoxin family
B2G65_RS02035	COG1194	a g-specific adenine glycosylase
B2G65_RS02075	COG0006	proline dipeptidase activity
B2G65_RS02080	COG2131	deaminase
B2G65_RS02100	COG1609	Transcriptional regulator
B2G65_RS02105	COG1621	beta-fructofuranosidase activity
B2G65_RS02110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2G65_RS02110	COG1263	PTS System
B2G65_RS02110	COG2190	(PTS) system
B2G65_RS02120	COG1940	carbohydrate kinase activity
B2G65_RS02125	COG1482	cell wall glycoprotein biosynthetic process
B2G65_RS02145	COG3942	CHAP domain
B2G65_RS02145	COG1388	LysM domain
B2G65_RS02170	COG1120	ATPase activity
B2G65_RS02175	COG4988	ABC transporter
B2G65_RS02180	COG1132	(ABC) transporter
B2G65_RS02195	COG1129	ABC transporter
B2G65_RS02205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B2G65_RS02210	COG1131	(ABC) transporter
B2G65_RS02220	COG0252	asparaginase activity
B2G65_RS02225	COG0561	phosphatase activity
B2G65_RS02235	COG0436	Aminotransferase
B2G65_RS02245	COG1335	isochorismatase
B2G65_RS02255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B2G65_RS02255	COG0574	Belongs to the PEP-utilizing enzyme family
B2G65_RS02280	COG2261	transglycosylase associated protein
B2G65_RS02285	COG0588	phosphoglycerate mutase activity
B2G65_RS02315	COG0484	heat shock protein binding
B2G65_RS02320	COG1024	Enoyl-CoA hydratase
B2G65_RS02345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B2G65_RS02350	COG1028	Short-chain dehydrogenase reductase Sdr
B2G65_RS02355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B2G65_RS02370	COG0439	Biotin carboxylase
B2G65_RS02395	COG3716	PTS system mannose fructose sorbose family IID component
B2G65_RS02400	COG3715	PTS system
B2G65_RS02410	COG0561	phosphatase activity
B2G65_RS02415	COG2252	PERMEase
B2G65_RS02420	COG0802	atpase or kinase
B2G65_RS02430	COG1316	TRANSCRIPTIONal
B2G65_RS02440	COG0537	adenosine 5'-monophosphoramidase activity
B2G65_RS02445	COG1131	(ABC) transporter
B2G65_RS02450	COG4473	ABC transporter
B2G65_RS02475	COG0195	Participates in both transcription termination and antitermination
B2G65_RS02480	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B2G65_RS02510	COG2217	Heavy metal translocating P-type atpase
B2G65_RS02570	COG2860	membrane
B2G65_RS02575	COG0561	phosphatase activity
B2G65_RS02595	COG1283	sodium-dependent phosphate transmembrane transporter activity
B2G65_RS02605	COG0656	L-ascorbic acid biosynthetic process
B2G65_RS02610	COG1755	Isoprenylcysteine carboxyl methyltransferase
B2G65_RS02650	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B2G65_RS02655	COG0446	pyridine nucleotide-disulphide oxidoreductase
B2G65_RS02680	COG1131	(ABC) transporter
B2G65_RS02715	COG0768	penicillin binding
B2G65_RS02725	COG0513	Belongs to the DEAD box helicase family
B2G65_RS02735	COG1126	abc transporter atp-binding protein
B2G65_RS02745	COG0492	ferredoxin-NADP+ reductase activity
B2G65_RS02750	COG1113	amino acid transport
B2G65_RS02755	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B2G65_RS02765	COG3579	cysteine-type endopeptidase activity
B2G65_RS02770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2G65_RS02795	COG0116	Belongs to the methyltransferase superfamily
B2G65_RS02810	COG2610	gluconate transmembrane transporter activity
B2G65_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
B2G65_RS02825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B2G65_RS02830	COG0183	Belongs to the thiolase family
B2G65_RS02835	COG0583	DNA-binding transcription factor activity
B2G65_RS02855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B2G65_RS02865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B2G65_RS02865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2G65_RS02875	COG0515	serine threonine protein kinase
B2G65_RS02875	COG2815	serine threonine protein kinase
B2G65_RS02885	COG4585	Histidine kinase
B2G65_RS02890	COG2197	response regulator
B2G65_RS02900	COG1098	S1 RNA binding domain
B2G65_RS02910	COG1739	Uncharacterized protein family UPF0029
B2G65_RS02915	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B2G65_RS03035	COG3561	AntA/AntB antirepressor
B2G65_RS03255	COG4824	toxin secretion phage lysis holin
B2G65_RS03260	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS03300	COG0383	alpha-mannosidase activity
B2G65_RS03315	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B2G65_RS03320	COG2723	6-phospho-beta-galactosidase activity
B2G65_RS03330	COG1175	transmembrane transport
B2G65_RS03335	COG0395	ABC-type sugar transport system, permease component
B2G65_RS03340	COG1653	transport
B2G65_RS03350	COG2972	Histidine kinase
B2G65_RS03355	COG4753	response regulator
B2G65_RS03355	COG2207	Transcriptional regulator
B2G65_RS03360	COG3250	beta-galactosidase activity
B2G65_RS03370	COG2226	methyltransferase
B2G65_RS03390	COG1605	Chorismate mutase
B2G65_RS03390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B2G65_RS03445	COG0673	inositol 2-dehydrogenase activity
B2G65_RS03455	COG0785	Cytochrome C biogenesis protein
B2G65_RS03460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B2G65_RS03475	COG2972	Histidine kinase
B2G65_RS03500	COG2235	arginine
B2G65_RS03515	COG1288	antiporter activity
B2G65_RS03520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2G65_RS03525	COG0549	Belongs to the carbamate kinase family
B2G65_RS03535	COG0742	ribosomal rna small subunit methyltransferase
B2G65_RS03545	COG3480	Lon protease (S16) C-terminal proteolytic domain
B2G65_RS03550	COG1609	Transcriptional regulator
B2G65_RS03555	COG4470	Protein conserved in bacteria
B2G65_RS03570	COG0783	Belongs to the Dps family
B2G65_RS03580	COG1940	carbohydrate kinase activity
B2G65_RS03585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B2G65_RS03590	COG1217	gtp-binding protein TYPA
B2G65_RS03625	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B2G65_RS03640	COG2302	S4 RNA-binding domain
B2G65_RS03645	COG3599	regulation of cell shape
B2G65_RS03660	COG0494	nUDIX hydrolase
B2G65_RS03665	COG0542	response to heat
B2G65_RS03670	COG4703	Protein of unknown function (DUF1797)
B2G65_RS03675	COG0765	amino acid transport
B2G65_RS03685	COG0415	Belongs to the DNA photolyase family
B2G65_RS03690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2G65_RS03715	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B2G65_RS03720	COG1438	arginine binding
B2G65_RS03725	COG0497	DNA recombination
B2G65_RS03740	COG2755	lipolytic protein G-D-S-L family
B2G65_RS03755	COG0582	viral genome integration into host DNA
B2G65_RS03765	COG1396	sequence-specific DNA binding
B2G65_RS03815	COG3723	Recombinational DNA repair protein, rece pathway
B2G65_RS03960	COG4824	toxin secretion phage lysis holin
B2G65_RS03965	COG0860	N-Acetylmuramoyl-L-alanine amidase
B2G65_RS03965	COG1388	LysM domain
B2G65_RS04005	COG2217	Heavy metal translocating P-type atpase
B2G65_RS04020	COG1827	regulation of RNA biosynthetic process
B2G65_RS04030	COG2116	formate transmembrane transporter activity
B2G65_RS04035	COG0768	penicillin binding
B2G65_RS04050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B2G65_RS04070	COG0513	Belongs to the DEAD box helicase family
B2G65_RS04085	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B2G65_RS04090	COG0204	Acyl-transferase
B2G65_RS04095	COG1596	polysaccharide export
B2G65_RS04095	COG1555	photosystem II stabilization
B2G65_RS04100	COG0658	competence protein
B2G65_RS04100	COG2333	competence protein COMEC
B2G65_RS04145	COG1187	pseudouridine synthase activity
B2G65_RS04160	COG2223	nitrite transmembrane transporter activity
B2G65_RS04165	COG4122	O-methyltransferase activity
B2G65_RS04180	COG1476	TRANSCRIPTIONal
B2G65_RS04205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2G65_RS04210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B2G65_RS04215	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B2G65_RS04235	COG0726	polysaccharide deacetylase
B2G65_RS04240	COG0513	Belongs to the DEAD box helicase family
B2G65_RS04260	COG1956	GAF domain-containing protein
B2G65_RS04265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B2G65_RS04275	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B2G65_RS04275	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B2G65_RS04300	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B2G65_RS04305	COG4109	DRTGG domain
B2G65_RS04355	COG2814	Major facilitator Superfamily
B2G65_RS04365	COG1187	pseudouridine synthase activity
B2G65_RS04380	COG0157	Belongs to the NadC ModD family
B2G65_RS04410	COG2723	6-phospho-beta-galactosidase activity
B2G65_RS04420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2G65_RS04420	COG3711	transcriptional antiterminator
B2G65_RS04430	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2G65_RS04440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2G65_RS04445	COG1126	abc transporter atp-binding protein
B2G65_RS04450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G65_RS04470	COG1696	Membrane protein involved in D-alanine export
B2G65_RS04480	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B2G65_RS04485	COG0657	acetylesterase activity
B2G65_RS04505	COG3833	ABC-type maltose transport systems, permease component
B2G65_RS04510	COG1175	transmembrane transport
B2G65_RS04515	COG2182	Extracellular solute-binding protein
B2G65_RS04520	COG1609	Transcriptional regulator
B2G65_RS04525	COG1640	4-alpha-glucanotransferase
B2G65_RS04530	COG0058	SHG alpha-glucan phosphorylase activity
B2G65_RS04555	COG1131	(ABC) transporter
B2G65_RS04560	COG1725	Transcriptional regulator
B2G65_RS04575	COG0469	pyruvate kinase activity
B2G65_RS04590	COG2824	Alkylphosphonate utilization operon protein PhnA
B2G65_RS04595	COG0765	amino acid transport
B2G65_RS04600	COG1126	abc transporter atp-binding protein
B2G65_RS04605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G65_RS04615	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B2G65_RS04620	COG1115	amino acid carrier protein
B2G65_RS04670	COG1136	(ABC) transporter
B2G65_RS04670	COG4591	ABC-type transport system involved in lipoprotein release permease component
B2G65_RS04700	COG0196	riboflavin kinase activity
B2G65_RS04715	COG0483	inositol monophosphate 1-phosphatase activity
B2G65_RS04720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B2G65_RS04720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B2G65_RS04730	COG0573	inorganic phosphate transmembrane transporter activity
B2G65_RS04735	COG0581	inorganic phosphate transmembrane transporter activity
B2G65_RS04750	COG0704	Plays a role in the regulation of phosphate uptake
B2G65_RS04765	COG0745	RESPONSE REGULATOR receiver
B2G65_RS04770	COG5002	protein histidine kinase activity
B2G65_RS04785	COG2813	Specifically methylates the guanine in position
B2G65_RS04790	COG0295	cytidine deaminase activity
B2G65_RS04795	COG1744	ABC transporter substrate-binding protein PnrA-like
B2G65_RS04800	COG3845	ABC transporter
B2G65_RS04805	COG4603	Belongs to the binding-protein-dependent transport system permease family
B2G65_RS04810	COG1079	Belongs to the binding-protein-dependent transport system permease family
B2G65_RS04815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B2G65_RS04820	COG4684	Psort location CytoplasmicMembrane, score
B2G65_RS04825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B2G65_RS04845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B2G65_RS04875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B2G65_RS04880	COG1328	CTP reductase activity
B2G65_RS04880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B2G65_RS04890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B2G65_RS04895	COG0352	thiamine-phosphate diphosphorylase activity
B2G65_RS04895	COG0351	phosphomethylpyrimidine kinase
B2G65_RS04905	COG0488	(ABC) transporter
B2G65_RS04925	COG2188	Transcriptional regulator
B2G65_RS04935	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B2G65_RS04955	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B2G65_RS04990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B2G65_RS04995	COG0511	ligase activity, forming carbon-carbon bonds
B2G65_RS05005	COG2851	Citrate transporter
B2G65_RS05020	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B2G65_RS05025	COG0511	ligase activity, forming carbon-carbon bonds
B2G65_RS05045	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B2G65_RS05050	COG0758	DNA mediated transformation
B2G65_RS05070	COG1272	protein, Hemolysin III
B2G65_RS05090	COG0346	lactoylglutathione lyase activity
B2G65_RS05095	COG3764	Sortase (surface protein transpeptidase)
B2G65_RS05115	COG1132	(ABC) transporter
B2G65_RS05120	COG1132	(ABC) transporter
B2G65_RS05150	COG2890	protein-(glutamine-N5) methyltransferase activity
B2G65_RS05175	COG2233	PERMEase
B2G65_RS05190	COG1174	glycine betaine transport
B2G65_RS05205	COG4221	oxidoreductase activity
B2G65_RS05210	COG0280	phosphate acetyltransferase
B2G65_RS05215	COG0564	pseudouridine synthase activity
B2G65_RS05225	COG2357	RelA SpoT domain protein
B2G65_RS05240	COG1104	cysteine desulfurase activity
B2G65_RS05255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B2G65_RS05265	COG0628	permease
B2G65_RS05275	COG0038	chloride channel
B2G65_RS05280	COG3700	Belongs to the class B bacterial acid phosphatase family
B2G65_RS05295	COG3493	citrate carrier protein
B2G65_RS05300	COG3290	protein histidine kinase activity
B2G65_RS05305	COG4565	transcriptional regulatory protein
B2G65_RS05315	COG1177	transmembrane transport
B2G65_RS05320	COG1176	ABC-type spermidine putrescine transport system, permease component I
B2G65_RS05335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B2G65_RS05355	COG0285	dihydrofolate synthase activity
B2G65_RS05390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B2G65_RS05405	COG1012	belongs to the aldehyde dehydrogenase family
B2G65_RS05415	COG4753	response regulator
B2G65_RS05415	COG2207	Transcriptional regulator
B2G65_RS05420	COG2972	Histidine kinase
B2G65_RS05425	COG3716	PTS system mannose fructose sorbose family IID component
B2G65_RS05430	COG3715	PTS system
B2G65_RS05465	COG0105	UTP biosynthetic process
B2G65_RS05505	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS05590	COG0740	serine-type endopeptidase activity
B2G65_RS05635	COG0582	viral genome integration into host DNA
B2G65_RS05705	COG0305	Participates in initiation and elongation during chromosome replication
B2G65_RS05765	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
B2G65_RS05770	COG1518	maintenance of DNA repeat elements
B2G65_RS05790	COG0647	UMP catabolic process
B2G65_RS05800	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B2G65_RS05820	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B2G65_RS05825	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B2G65_RS05830	COG3442	glutamine amidotransferase
B2G65_RS05835	COG0095	Lipoate-protein ligase
B2G65_RS05840	COG5492	domain, Protein
B2G65_RS05860	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2G65_RS05865	COG0022	dehydrogenase e1 component
B2G65_RS05865	COG0508	dehydrogenase complex catalyzes the overall conversion of
B2G65_RS05870	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B2G65_RS05875	COG0488	(ABC) transporter
B2G65_RS05895	COG1129	ABC transporter
B2G65_RS05915	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B2G65_RS05920	COG0457	Tetratricopeptide repeat
B2G65_RS05925	COG0628	permease
B2G65_RS05930	COG1051	belongs to the nudix hydrolase family
B2G65_RS06060	COG1783	phage Terminase large subunit
B2G65_RS06190	COG0582	viral genome integration into host DNA
B2G65_RS06195	COG1088	dTDP-glucose 4,6-dehydratase activity
B2G65_RS06205	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B2G65_RS06210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B2G65_RS06220	COG2384	SAM-dependent methyltransferase
B2G65_RS06225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B2G65_RS06240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B2G65_RS06240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B2G65_RS06245	COG0300	oxidoreductase activity
B2G65_RS06255	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B2G65_RS06260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B2G65_RS06305	COG0539	negative regulation of cytoplasmic translation
B2G65_RS06325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B2G65_RS06340	COG0187	DNA topoisomerase II activity
B2G65_RS06360	COG0765	amino acid transport
B2G65_RS06365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G65_RS06390	COG0583	DNA-binding transcription factor activity
B2G65_RS06450	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B2G65_RS06460	COG3425	synthase
B2G65_RS06495	COG0745	RESPONSE REGULATOR receiver
B2G65_RS06500	COG2357	RelA SpoT domain protein
B2G65_RS06505	COG0737	Belongs to the 5'-nucleotidase family
B2G65_RS06510	COG0242	peptide deformylase activity
B2G65_RS06520	COG0488	(ABC) transporter
B2G65_RS06540	COG0105	UTP biosynthetic process
B2G65_RS06560	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS06560	COG1388	LysM domain
B2G65_RS06565	COG1388	LysM domain
B2G65_RS06565	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS06570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B2G65_RS06570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2G65_RS06570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B2G65_RS06575	COG1105	Belongs to the carbohydrate kinase PfkB family
B2G65_RS06580	COG1349	DNA-binding transcription factor activity
B2G65_RS06630	COG1837	Belongs to the UPF0109 family
B2G65_RS06640	COG0584	glycerophosphoryl diester phosphodiesterase
B2G65_RS06645	COG0577	efflux transmembrane transporter activity
B2G65_RS06650	COG1136	(ABC) transporter
B2G65_RS06655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B2G65_RS06690	COG0564	pseudouridine synthase activity
B2G65_RS06700	COG0583	DNA-binding transcription factor activity
B2G65_RS06705	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B2G65_RS06730	COG1104	cysteine desulfurase activity
B2G65_RS06740	COG0285	dihydrofolate synthase activity
B2G65_RS06745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B2G65_RS06765	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B2G65_RS06770	COG1368	sulfuric ester hydrolase activity
B2G65_RS06830	COG1216	Glycosyl transferase, family 2
B2G65_RS06875	COG2151	metal-sulfur cluster biosynthetic enzyme
B2G65_RS06880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B2G65_RS06885	COG0358	DNA primase activity
B2G65_RS06890	COG1970	mechanosensitive ion channel activity
B2G65_RS06900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G65_RS06915	COG2321	neutral zinc metallopeptidase
B2G65_RS06925	COG0577	efflux transmembrane transporter activity
B2G65_RS07010	COG1597	lipid kinase activity
B2G65_RS07020	COG4708	membrane
B2G65_RS07045	COG1131	(ABC) transporter
B2G65_RS07120	COG0038	chloride channel
B2G65_RS07130	COG0716	FMN binding
B2G65_RS07135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B2G65_RS07145	COG2222	sugar isomerase
B2G65_RS07150	COG2188	Transcriptional regulator
B2G65_RS07185	COG0436	Aminotransferase
B2G65_RS07190	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B2G65_RS07190	COG1199	ATP-dependent helicase activity
B2G65_RS07205	COG2177	Part of the ABC transporter FtsEX involved in
B2G65_RS07210	COG2884	Cell division ATP-binding protein ftsE
B2G65_RS07220	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B2G65_RS07225	COG0546	phosphoglycolate phosphatase activity
B2G65_RS07230	COG0800	Aldolase
B2G65_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
B2G65_RS07260	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2G65_RS07265	COG3715	PTS system
B2G65_RS07270	COG3716	PTS system mannose fructose sorbose family IID component
B2G65_RS07280	COG1609	Transcriptional regulator
B2G65_RS07295	COG1078	dGTPase activity
B2G65_RS07330	COG0772	Belongs to the SEDS family
B2G65_RS07340	COG1164	Oligoendopeptidase f
B2G65_RS07345	COG0386	Belongs to the glutathione peroxidase family
B2G65_RS07395	COG4443	Transcriptional Coactivator p15 (PC4)
B2G65_RS07400	COG0826	peptidase U32
B2G65_RS07445	COG2183	response to ionizing radiation
B2G65_RS07455	COG0701	Predicted permease
B2G65_RS07460	COG3689	TIGRFAM TIGR03943 family protein
B2G65_RS07470	COG1263	PTS System
B2G65_RS07470	COG2190	(PTS) system
B2G65_RS07470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2G65_RS07475	COG3711	transcriptional antiterminator
B2G65_RS07480	COG0477	Major facilitator Superfamily
B2G65_RS07485	COG0552	protein localization to endoplasmic reticulum
B2G65_RS07490	COG0561	phosphatase activity
B2G65_RS07495	COG0561	phosphatase activity
B2G65_RS07505	COG0124	histidyl-tRNA synthetase
B2G65_RS07520	COG0017	Asparaginyl-tRNA synthetase
B2G65_RS07620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B2G65_RS07630	COG1196	nuclear chromosome segregation
B2G65_RS07640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B2G65_RS07645	COG5002	protein histidine kinase activity
B2G65_RS07650	COG0745	RESPONSE REGULATOR receiver
B2G65_RS07665	COG0183	Belongs to the thiolase family
B2G65_RS07685	COG4555	ABC transporter
B2G65_RS07695	COG0438	transferase activity, transferring glycosyl groups
B2G65_RS07705	COG1609	Transcriptional regulator
B2G65_RS07710	COG0006	proline dipeptidase activity
B2G65_RS07715	COG0778	Nitroreductase
B2G65_RS07725	COG0463	Glycosyl transferase, family 2
B2G65_RS07755	COG0557	exoribonuclease II activity
B2G65_RS07770	COG2814	Major facilitator Superfamily
B2G65_RS07775	COG0433	COG0433 Predicted ATPase
B2G65_RS07870	COG2274	protein secretion by the type I secretion system
B2G65_RS07890	COG3279	Response regulator of the LytR AlgR family
B2G65_RS07930	COG2274	protein secretion by the type I secretion system
B2G65_RS07955	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B2G65_RS07965	COG1573	uracil-dna glycosylase
B2G65_RS07970	COG1702	phosphate starvation-inducible protein PhoH
B2G65_RS08060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B2G65_RS08070	COG0494	nUDIX hydrolase
B2G65_RS08085	COG0673	inositol 2-dehydrogenase activity
B2G65_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
B2G65_RS08170	COG1304	FMN binding
B2G65_RS08180	COG0708	Exodeoxyribonuclease III
B2G65_RS08185	COG1393	Belongs to the ArsC family
B2G65_RS08215	COG0470	DNA polymerase III
B2G65_RS08245	COG2244	polysaccharide biosynthetic process
B2G65_RS08255	COG1120	ATPase activity
B2G65_RS08260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B2G65_RS08265	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2G65_RS08270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B2G65_RS08285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B2G65_RS08290	COG1253	flavin adenine dinucleotide binding
B2G65_RS08295	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B2G65_RS08300	COG1242	4 iron, 4 sulfur cluster binding
B2G65_RS08305	COG0671	phosphoesterase, PA-phosphatase related
B2G65_RS08310	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B2G65_RS08325	COG1187	pseudouridine synthase activity
B2G65_RS08380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2G65_RS08385	COG1254	Belongs to the acylphosphatase family
B2G65_RS08400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B2G65_RS08420	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B2G65_RS08430	COG1484	DNA-dependent DNA replication
B2G65_RS08450	COG0745	RESPONSE REGULATOR receiver
B2G65_RS08465	COG1704	LemA family
B2G65_RS08475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B2G65_RS08480	COG0569	domain protein
B2G65_RS08490	COG1114	Component of the transport system for branched-chain amino acids
B2G65_RS08505	COG1464	Belongs to the NlpA lipoprotein family
B2G65_RS08510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B2G65_RS08530	COG2226	methyltransferase
B2G65_RS08535	COG0799	negative regulation of ribosome biogenesis
B2G65_RS08540	COG1713	HD superfamily hydrolase involved in NAD metabolism
B2G65_RS08550	COG1534	Rna-binding protein
B2G65_RS08555	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B2G65_RS08560	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B2G65_RS08600	COG1929	Belongs to the glycerate kinase type-1 family
B2G65_RS08605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B2G65_RS08635	COG0577	efflux transmembrane transporter activity
B2G65_RS08640	COG1136	(ABC) transporter
B2G65_RS08670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2G65_RS08670	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2G65_RS08675	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2G65_RS08725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B2G65_RS08730	COG1476	TRANSCRIPTIONal
B2G65_RS08750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B2G65_RS08760	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B2G65_RS08780	COG1045	serine acetyltransferase
B2G65_RS08795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B2G65_RS08800	COG3037	sugar-specific permease SgaT UlaA
B2G65_RS08810	COG3711	transcriptional antiterminator
B2G65_RS08840	COG1846	Transcriptional regulator
B2G65_RS08860	COG4589	Belongs to the CDS family
B2G65_RS08870	COG1862	Preprotein translocase
B2G65_RS08880	COG1523	belongs to the glycosyl hydrolase 13 family
B2G65_RS08895	COG3842	ATPase activity
B2G65_RS08940	COG2190	(PTS) system
B2G65_RS08940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2G65_RS08940	COG1263	PTS System
B2G65_RS08945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B2G65_RS08960	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B2G65_RS08965	COG0512	Glutamine amidotransferase of anthranilate synthase
B2G65_RS08970	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B2G65_RS09000	COG0601	transmembrane transport
B2G65_RS09010	COG1122	ATPase activity
B2G65_RS09030	COG0803	Belongs to the bacterial solute-binding protein 9 family
B2G65_RS09060	COG3711	transcriptional antiterminator
B2G65_RS09075	COG3942	CHAP domain
B2G65_RS09075	COG1705	Flagellar rod assembly protein muramidase FlgJ
B2G65_RS09080	COG2205	protein histidine kinase activity
B2G65_RS09085	COG0745	RESPONSE REGULATOR receiver
B2G65_RS09090	COG0577	efflux transmembrane transporter activity
B2G65_RS09095	COG1136	(ABC) transporter
B2G65_RS09160	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B2G65_RS09175	COG1882	Formate acetyltransferase
B2G65_RS09180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2G65_RS09185	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B2G65_RS09190	COG1447	Phosphotransferase system cellobiose-specific component IIA
B2G65_RS09195	COG2390	Transcriptional regulator
B2G65_RS09200	COG1349	DNA-binding transcription factor activity
B2G65_RS09205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B2G65_RS09225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B2G65_RS09240	COG0564	pseudouridine synthase activity
B2G65_RS09275	COG0542	response to heat
B2G65_RS09280	COG4463	regulation of RNA biosynthetic process
B2G65_RS09295	COG0450	alkyl hydroperoxide reductase
B2G65_RS09310	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B2G65_RS09320	COG3404	Formiminotransferase-cyclodeaminase
B2G65_RS09335	COG0531	amino acid
B2G65_RS09365	COG3590	peptidase
B2G65_RS09370	COG0366	Alpha amylase catalytic
B2G65_RS09375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B2G65_RS09375	COG1263	PTS System
B2G65_RS09380	COG2188	Transcriptional regulator
B2G65_RS09390	COG1733	regulation of RNA biosynthetic process
B2G65_RS09395	COG2514	catechol 2,3-dioxygenase activity
B2G65_RS09405	COG0602	queuosine metabolic process
B2G65_RS09425	COG1328	CTP reductase activity
B2G65_RS09450	COG1393	Belongs to the ArsC family
B2G65_RS09465	COG0519	Catalyzes the synthesis of GMP from XMP
B2G65_RS09475	COG2814	Major facilitator Superfamily
B2G65_RS09510	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2G65_RS09515	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2G65_RS09520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2G65_RS09605	COG1511	domain protein
B2G65_RS09625	COG0305	Participates in initiation and elongation during chromosome replication
B2G65_RS09655	COG1760	l-serine dehydratase
B2G65_RS09660	COG1760	l-serine dehydratase
B2G65_RS09665	COG0741	lytic transglycosylase activity
B2G65_RS09670	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B2G65_RS09685	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B2G65_RS09695	COG0612	Peptidase, M16
B2G65_RS09740	COG0516	GMP reductase activity
B2G65_RS09740	COG0517	IMP dehydrogenase activity
B2G65_RS09750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B2G65_RS09755	COG0488	(ABC) transporter
B2G65_RS09790	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B2G65_RS09795	COG1475	DNA binding