locus-tag	class	description
HKU360_RS00010	COG0592	DNA-directed DNA polymerase activity
HKU360_RS00020	COG0012	GTP binding
HKU360_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKU360_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HKU360_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKU360_RS00065	COG0531	amino acid
HKU360_RS00240	COG3942	CHAP domain
HKU360_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKU360_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKU360_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKU360_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKU360_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKU360_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKU360_RS00350	COG1454	alcohol dehydrogenase
HKU360_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
HKU360_RS00355	COG1064	alcohol dehydrogenase
HKU360_RS00360	COG0534	Mate efflux family protein
HKU360_RS00470	COG0201	protein transport
HKU360_RS00605	COG1121	(ABC) transporter
HKU360_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HKU360_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU360_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKU360_RS00650	COG1459	type II secretion system
HKU360_RS00655	COG4537	Required for transformation and DNA binding
HKU360_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKU360_RS00700	COG1363	Peptidase, m42
HKU360_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKU360_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKU360_RS00725	COG1428	Deoxynucleoside kinase
HKU360_RS00730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKU360_RS00770	COG4509	Sortase family
HKU360_RS00795	COG2031	fatty acid transporter
HKU360_RS00810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKU360_RS00825	COG0251	oxidation-reduction process
HKU360_RS00840	COG1269	ATP hydrolysis coupled proton transport
HKU360_RS00845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKU360_RS00855	COG1527	subunit (C
HKU360_RS00860	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKU360_RS00895	COG1744	ABC transporter substrate-binding protein PnrA-like
HKU360_RS00935	COG0626	cystathionine gamma-synthase activity
HKU360_RS00945	COG3037	sugar-specific permease SgaT UlaA
HKU360_RS00965	COG3623	hexulose-6-phosphate isomerase
HKU360_RS00985	COG4175	Glycine betaine
HKU360_RS00985	COG3448	diguanylate cyclase activity
HKU360_RS00995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKU360_RS00995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKU360_RS01015	COG3969	phosphoadenosine phosphosulfate
HKU360_RS01020	COG1475	DNA binding
HKU360_RS01030	COG2801	Transposase and inactivated derivatives
HKU360_RS01035	COG2801	Transposase and inactivated derivatives
HKU360_RS01050	COG0157	Belongs to the NadC ModD family
HKU360_RS01055	COG2801	Transposase and inactivated derivatives
HKU360_RS01075	COG1268	BioY protein
HKU360_RS01080	COG5433	transposase activity
HKU360_RS01090	COG1234	tRNA 3'-trailer cleavage
HKU360_RS01120	COG5433	transposase activity
HKU360_RS01130	COG0705	Rhomboid family
HKU360_RS01130	COG0457	Tetratricopeptide repeat
HKU360_RS01150	COG1132	(ABC) transporter
HKU360_RS01155	COG1132	(ABC) transporter
HKU360_RS01165	COG0756	dUTP diphosphatase activity
HKU360_RS01190	COG3290	protein histidine kinase activity
HKU360_RS01215	COG1847	R3H domain protein
HKU360_RS01235	COG1175	transmembrane transport
HKU360_RS01240	COG0395	ABC-type sugar transport system, permease component
HKU360_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKU360_RS01265	COG0084	hydrolase, TatD family'
HKU360_RS01290	COG1564	THIamine pyrophosphokinase
HKU360_RS01305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKU360_RS01340	COG0765	amino acid transport
HKU360_RS01360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKU360_RS01370	COG0719	Fe-S assembly protein
HKU360_RS01375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKU360_RS01390	COG1686	Belongs to the peptidase S11 family
HKU360_RS01395	COG1686	Belongs to the peptidase S11 family
HKU360_RS01400	COG4166	transmembrane transport
HKU360_RS01405	COG0601	transmembrane transport
HKU360_RS01410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKU360_RS01415	COG0444	Belongs to the ABC transporter superfamily
HKU360_RS01465	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HKU360_RS01470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKU360_RS01475	COG1534	Rna-binding protein
HKU360_RS01485	COG1713	HD superfamily hydrolase involved in NAD metabolism
HKU360_RS01490	COG0799	negative regulation of ribosome biogenesis
HKU360_RS01495	COG2226	methyltransferase
HKU360_RS01510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU360_RS01515	COG1464	Belongs to the NlpA lipoprotein family
HKU360_RS01530	COG1114	Component of the transport system for branched-chain amino acids
HKU360_RS01540	COG0569	domain protein
HKU360_RS01545	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HKU360_RS01555	COG1704	LemA family
HKU360_RS01570	COG0745	RESPONSE REGULATOR receiver
HKU360_RS01590	COG1484	DNA-dependent DNA replication
HKU360_RS01600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HKU360_RS01620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKU360_RS01635	COG1254	Belongs to the acylphosphatase family
HKU360_RS01640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKU360_RS01695	COG1187	pseudouridine synthase activity
HKU360_RS01710	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKU360_RS01715	COG0671	phosphoesterase, PA-phosphatase related
HKU360_RS01720	COG1242	4 iron, 4 sulfur cluster binding
HKU360_RS01725	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HKU360_RS01730	COG1253	flavin adenine dinucleotide binding
HKU360_RS01735	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKU360_RS01750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKU360_RS01755	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKU360_RS01760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HKU360_RS01765	COG1120	ATPase activity
HKU360_RS01775	COG2244	polysaccharide biosynthetic process
HKU360_RS01795	COG5433	transposase activity
HKU360_RS01810	COG0470	DNA polymerase III
HKU360_RS01840	COG1393	Belongs to the ArsC family
HKU360_RS01845	COG0708	Exodeoxyribonuclease III
HKU360_RS01850	COG1304	FMN binding
HKU360_RS01930	COG1028	Short-chain dehydrogenase reductase Sdr
HKU360_RS01935	COG0673	inositol 2-dehydrogenase activity
HKU360_RS01950	COG0494	nUDIX hydrolase
HKU360_RS01960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKU360_RS02020	COG2996	Protein conserved in bacteria
HKU360_RS02045	COG1702	phosphate starvation-inducible protein PhoH
HKU360_RS02050	COG1573	uracil-dna glycosylase
HKU360_RS02060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HKU360_RS02075	COG3328	transposase activity
HKU360_RS02140	COG0433	COG0433 Predicted ATPase
HKU360_RS02145	COG2814	Major facilitator Superfamily
HKU360_RS02155	COG0557	exoribonuclease II activity
HKU360_RS02185	COG0463	Glycosyl transferase, family 2
HKU360_RS02195	COG0778	Nitroreductase
HKU360_RS02200	COG0006	proline dipeptidase activity
HKU360_RS02205	COG1609	Transcriptional regulator
HKU360_RS02215	COG0438	transferase activity, transferring glycosyl groups
HKU360_RS02225	COG4555	ABC transporter
HKU360_RS02245	COG0183	Belongs to the thiolase family
HKU360_RS02260	COG0745	RESPONSE REGULATOR receiver
HKU360_RS02265	COG5002	protein histidine kinase activity
HKU360_RS02270	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HKU360_RS02280	COG1196	nuclear chromosome segregation
HKU360_RS02290	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKU360_RS02390	COG0561	phosphatase activity
HKU360_RS02395	COG0552	protein localization to endoplasmic reticulum
HKU360_RS02400	COG0477	Major facilitator Superfamily
HKU360_RS02405	COG3711	transcriptional antiterminator
HKU360_RS02410	COG1263	PTS System
HKU360_RS02410	COG2190	(PTS) system
HKU360_RS02410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU360_RS02420	COG3689	TIGRFAM TIGR03943 family protein
HKU360_RS02425	COG0701	Predicted permease
HKU360_RS02435	COG2183	response to ionizing radiation
HKU360_RS02480	COG0826	peptidase U32
HKU360_RS02485	COG4443	Transcriptional Coactivator p15 (PC4)
HKU360_RS02505	COG0588	phosphoglycerate mutase activity
HKU360_RS02535	COG0386	Belongs to the glutathione peroxidase family
HKU360_RS02540	COG1164	Oligoendopeptidase f
HKU360_RS02550	COG0772	Belongs to the SEDS family
HKU360_RS02585	COG1078	dGTPase activity
HKU360_RS02600	COG1609	Transcriptional regulator
HKU360_RS02610	COG3716	PTS system mannose fructose sorbose family IID component
HKU360_RS02615	COG3715	PTS system
HKU360_RS02620	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU360_RS02635	COG1028	Short-chain dehydrogenase reductase Sdr
HKU360_RS02650	COG0800	Aldolase
HKU360_RS02655	COG0546	phosphoglycolate phosphatase activity
HKU360_RS02660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKU360_RS02670	COG2884	Cell division ATP-binding protein ftsE
HKU360_RS02675	COG2177	Part of the ABC transporter FtsEX involved in
HKU360_RS02690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKU360_RS02690	COG1199	ATP-dependent helicase activity
HKU360_RS02695	COG0436	Aminotransferase
HKU360_RS02730	COG2188	Transcriptional regulator
HKU360_RS02735	COG2222	sugar isomerase
HKU360_RS02745	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HKU360_RS02750	COG0716	FMN binding
HKU360_RS02760	COG0038	chloride channel
HKU360_RS02845	COG1131	(ABC) transporter
HKU360_RS02865	COG4708	membrane
HKU360_RS02875	COG1597	lipid kinase activity
HKU360_RS02960	COG0577	efflux transmembrane transporter activity
HKU360_RS02970	COG2321	neutral zinc metallopeptidase
HKU360_RS02985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU360_RS02995	COG1970	mechanosensitive ion channel activity
HKU360_RS03000	COG0358	DNA primase activity
HKU360_RS03005	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKU360_RS03010	COG2151	metal-sulfur cluster biosynthetic enzyme
HKU360_RS03055	COG1216	Glycosyl transferase, family 2
HKU360_RS03110	COG1368	sulfuric ester hydrolase activity
HKU360_RS03115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HKU360_RS03135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKU360_RS03140	COG0285	dihydrofolate synthase activity
HKU360_RS03150	COG1104	cysteine desulfurase activity
HKU360_RS03175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HKU360_RS03180	COG0583	DNA-binding transcription factor activity
HKU360_RS03190	COG0564	pseudouridine synthase activity
HKU360_RS03220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKU360_RS03225	COG1136	(ABC) transporter
HKU360_RS03230	COG0577	efflux transmembrane transporter activity
HKU360_RS03235	COG0584	glycerophosphoryl diester phosphodiesterase
HKU360_RS03245	COG1837	Belongs to the UPF0109 family
HKU360_RS03295	COG1349	DNA-binding transcription factor activity
HKU360_RS03300	COG1105	Belongs to the carbohydrate kinase PfkB family
HKU360_RS03305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HKU360_RS03305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKU360_RS03305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HKU360_RS03310	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU360_RS03310	COG1388	LysM domain
HKU360_RS03315	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU360_RS03315	COG1388	LysM domain
HKU360_RS03320	COG2801	Transposase and inactivated derivatives
HKU360_RS03335	COG0105	UTP biosynthetic process
HKU360_RS03355	COG0488	(ABC) transporter
HKU360_RS03365	COG0242	peptide deformylase activity
HKU360_RS03370	COG0737	Belongs to the 5'-nucleotidase family
HKU360_RS03375	COG2357	RelA SpoT domain protein
HKU360_RS03380	COG0745	RESPONSE REGULATOR receiver
HKU360_RS03420	COG3425	synthase
HKU360_RS03430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKU360_RS03490	COG0583	DNA-binding transcription factor activity
HKU360_RS03515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU360_RS03520	COG0765	amino acid transport
HKU360_RS03540	COG0187	DNA topoisomerase II activity
HKU360_RS03550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKU360_RS03570	COG0539	negative regulation of cytoplasmic translation
HKU360_RS03605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKU360_RS03610	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HKU360_RS03620	COG0300	oxidoreductase activity
HKU360_RS03625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HKU360_RS03625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HKU360_RS03640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKU360_RS03645	COG2384	SAM-dependent methyltransferase
HKU360_RS03655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HKU360_RS03660	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKU360_RS03670	COG1088	dTDP-glucose 4,6-dehydratase activity
HKU360_RS03675	COG0582	viral genome integration into host DNA
HKU360_RS03695	COG3561	AntA/AntB antirepressor
HKU360_RS03935	COG1051	belongs to the nudix hydrolase family
HKU360_RS03940	COG0628	permease
HKU360_RS03945	COG0457	Tetratricopeptide repeat
HKU360_RS03950	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HKU360_RS03965	COG1129	ABC transporter
HKU360_RS03985	COG0488	(ABC) transporter
HKU360_RS03990	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HKU360_RS03995	COG0022	dehydrogenase e1 component
HKU360_RS03995	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKU360_RS04000	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKU360_RS04015	COG5492	domain, Protein
HKU360_RS04020	COG0095	Lipoate-protein ligase
HKU360_RS04025	COG3442	glutamine amidotransferase
HKU360_RS04030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKU360_RS04035	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKU360_RS04055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HKU360_RS04065	COG0647	UMP catabolic process
HKU360_RS04080	COG1518	maintenance of DNA repeat elements
HKU360_RS04085	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKU360_RS04100	COG0105	UTP biosynthetic process
HKU360_RS04105	COG5433	transposase activity
HKU360_RS04145	COG3715	PTS system
HKU360_RS04150	COG3716	PTS system mannose fructose sorbose family IID component
HKU360_RS04155	COG2972	Histidine kinase
HKU360_RS04160	COG4753	response regulator
HKU360_RS04160	COG2207	Transcriptional regulator
HKU360_RS04170	COG1012	belongs to the aldehyde dehydrogenase family
HKU360_RS04185	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKU360_RS04265	COG1131	(ABC) transporter
HKU360_RS04280	COG1396	sequence-specific DNA binding
HKU360_RS04315	COG0285	dihydrofolate synthase activity
HKU360_RS04335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKU360_RS04350	COG1176	ABC-type spermidine putrescine transport system, permease component I
HKU360_RS04355	COG1177	transmembrane transport
HKU360_RS04365	COG4565	transcriptional regulatory protein
HKU360_RS04370	COG3290	protein histidine kinase activity
HKU360_RS04375	COG3493	citrate carrier protein
HKU360_RS04390	COG3700	Belongs to the class B bacterial acid phosphatase family
HKU360_RS04395	COG0038	chloride channel
HKU360_RS04405	COG0628	permease
HKU360_RS04415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HKU360_RS04430	COG1104	cysteine desulfurase activity
HKU360_RS04445	COG2357	RelA SpoT domain protein
HKU360_RS04455	COG0564	pseudouridine synthase activity
HKU360_RS04460	COG0280	phosphate acetyltransferase
HKU360_RS04465	COG4221	oxidoreductase activity
HKU360_RS04480	COG1174	glycine betaine transport
HKU360_RS04495	COG2233	PERMEase
HKU360_RS04520	COG2890	protein-(glutamine-N5) methyltransferase activity
HKU360_RS04550	COG1132	(ABC) transporter
HKU360_RS04555	COG1132	(ABC) transporter
HKU360_RS04575	COG3764	Sortase (surface protein transpeptidase)
HKU360_RS04580	COG0346	lactoylglutathione lyase activity
HKU360_RS04595	COG1272	protein, Hemolysin III
HKU360_RS04615	COG0758	DNA mediated transformation
HKU360_RS04620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKU360_RS04660	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKU360_RS04680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKU360_RS04690	COG2188	Transcriptional regulator
HKU360_RS04710	COG0488	(ABC) transporter
HKU360_RS04720	COG0351	phosphomethylpyrimidine kinase
HKU360_RS04720	COG0352	thiamine-phosphate diphosphorylase activity
HKU360_RS04725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HKU360_RS04730	COG1328	CTP reductase activity
HKU360_RS04730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKU360_RS04735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKU360_RS04765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKU360_RS04775	COG0095	Lipoate-protein ligase
HKU360_RS04785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKU360_RS04790	COG4684	Psort location CytoplasmicMembrane, score
HKU360_RS04795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKU360_RS04800	COG1079	Belongs to the binding-protein-dependent transport system permease family
HKU360_RS04805	COG4603	Belongs to the binding-protein-dependent transport system permease family
HKU360_RS04810	COG3845	ABC transporter
HKU360_RS04815	COG1744	ABC transporter substrate-binding protein PnrA-like
HKU360_RS04820	COG0295	cytidine deaminase activity
HKU360_RS04825	COG2813	Specifically methylates the guanine in position
HKU360_RS04840	COG5002	protein histidine kinase activity
HKU360_RS04845	COG0745	RESPONSE REGULATOR receiver
HKU360_RS04855	COG0704	Plays a role in the regulation of phosphate uptake
HKU360_RS04870	COG0581	inorganic phosphate transmembrane transporter activity
HKU360_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
HKU360_RS04885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKU360_RS04885	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HKU360_RS04890	COG0483	inositol monophosphate 1-phosphatase activity
HKU360_RS04905	COG0196	riboflavin kinase activity
HKU360_RS04935	COG4591	ABC-type transport system involved in lipoprotein release permease component
HKU360_RS04935	COG1136	(ABC) transporter
HKU360_RS04985	COG1115	amino acid carrier protein
HKU360_RS04990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKU360_RS05000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU360_RS05005	COG1126	abc transporter atp-binding protein
HKU360_RS05010	COG0765	amino acid transport
HKU360_RS05015	COG2824	Alkylphosphonate utilization operon protein PhnA
HKU360_RS05030	COG0469	pyruvate kinase activity
HKU360_RS05045	COG1725	Transcriptional regulator
HKU360_RS05050	COG1131	(ABC) transporter
HKU360_RS05070	COG0058	SHG alpha-glucan phosphorylase activity
HKU360_RS05075	COG1640	4-alpha-glucanotransferase
HKU360_RS05080	COG1609	Transcriptional regulator
HKU360_RS05085	COG2182	Extracellular solute-binding protein
HKU360_RS05090	COG1175	transmembrane transport
HKU360_RS05095	COG3833	ABC-type maltose transport systems, permease component
HKU360_RS05110	COG0657	acetylesterase activity
HKU360_RS05115	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKU360_RS05125	COG1696	Membrane protein involved in D-alanine export
HKU360_RS05145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU360_RS05150	COG1126	abc transporter atp-binding protein
HKU360_RS05160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU360_RS05170	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU360_RS05180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKU360_RS05180	COG3711	transcriptional antiterminator
HKU360_RS05190	COG2723	6-phospho-beta-galactosidase activity
HKU360_RS05215	COG2801	Transposase and inactivated derivatives
HKU360_RS05220	COG1187	pseudouridine synthase activity
HKU360_RS05230	COG2814	Major facilitator Superfamily
HKU360_RS05270	COG1132	(ABC) transporter
HKU360_RS05275	COG1132	(ABC) transporter
HKU360_RS05275	COG2375	cellular response to nickel ion
HKU360_RS05315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKU360_RS05325	COG0741	lytic transglycosylase activity
HKU360_RS05325	COG0791	NLP P60 protein
HKU360_RS05370	COG2946	Replication initiation factor
HKU360_RS05375	COG1674	ftsk spoiiie
HKU360_RS05390	COG1129	ABC transporter
HKU360_RS05405	COG1309	transcriptional regulator
HKU360_RS05440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKU360_RS05440	COG0551	DNA topoisomerase type I activity
HKU360_RS05500	COG1484	DNA-dependent DNA replication
HKU360_RS05545	COG4109	DRTGG domain
HKU360_RS05575	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HKU360_RS05575	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HKU360_RS05580	COG5433	transposase activity
HKU360_RS05585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKU360_RS05590	COG1956	GAF domain-containing protein
HKU360_RS05610	COG0513	Belongs to the DEAD box helicase family
HKU360_RS05615	COG0726	polysaccharide deacetylase
HKU360_RS05635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HKU360_RS05640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKU360_RS05645	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKU360_RS05660	COG2801	Transposase and inactivated derivatives
HKU360_RS05665	COG2801	Transposase and inactivated derivatives
HKU360_RS05680	COG1476	TRANSCRIPTIONal
HKU360_RS05695	COG4122	O-methyltransferase activity
HKU360_RS05700	COG2223	nitrite transmembrane transporter activity
HKU360_RS05715	COG1187	pseudouridine synthase activity
HKU360_RS05760	COG0658	competence protein
HKU360_RS05760	COG2333	competence protein COMEC
HKU360_RS05765	COG1555	photosystem II stabilization
HKU360_RS05765	COG1596	polysaccharide export
HKU360_RS05770	COG0204	Acyl-transferase
HKU360_RS05775	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HKU360_RS05790	COG0513	Belongs to the DEAD box helicase family
HKU360_RS05805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKU360_RS05820	COG2116	formate transmembrane transporter activity
HKU360_RS05830	COG1827	regulation of RNA biosynthetic process
HKU360_RS05845	COG2217	Heavy metal translocating P-type atpase
HKU360_RS05860	COG3177	Filamentation induced by cAMP protein fic
HKU360_RS05965	COG0740	serine-type endopeptidase activity
HKU360_RS06005	COG1598	PFAM Uncharacterised protein family UPF0150
HKU360_RS06095	COG1111	helicase
HKU360_RS06095	COG1205	dead DEAH box helicase
HKU360_RS06130	COG1396	sequence-specific DNA binding
HKU360_RS06140	COG0582	viral genome integration into host DNA
HKU360_RS06155	COG2755	lipolytic protein G-D-S-L family
HKU360_RS06170	COG0497	DNA recombination
HKU360_RS06175	COG1438	arginine binding
HKU360_RS06180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HKU360_RS06205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKU360_RS06210	COG0415	Belongs to the DNA photolyase family
HKU360_RS06220	COG0765	amino acid transport
HKU360_RS06225	COG4703	Protein of unknown function (DUF1797)
HKU360_RS06230	COG0542	response to heat
HKU360_RS06235	COG0494	nUDIX hydrolase
HKU360_RS06250	COG3599	regulation of cell shape
HKU360_RS06255	COG2302	S4 RNA-binding domain
HKU360_RS06270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKU360_RS06305	COG1217	gtp-binding protein TYPA
HKU360_RS06310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKU360_RS06315	COG1940	carbohydrate kinase activity
HKU360_RS06325	COG0783	Belongs to the Dps family
HKU360_RS06340	COG4470	Protein conserved in bacteria
HKU360_RS06345	COG1609	Transcriptional regulator
HKU360_RS06350	COG3480	Lon protease (S16) C-terminal proteolytic domain
HKU360_RS06360	COG0742	ribosomal rna small subunit methyltransferase
HKU360_RS06370	COG0549	Belongs to the carbamate kinase family
HKU360_RS06375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKU360_RS06380	COG1288	antiporter activity
HKU360_RS06395	COG2235	arginine
HKU360_RS06420	COG2972	Histidine kinase
HKU360_RS06435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKU360_RS06440	COG0785	Cytochrome C biogenesis protein
HKU360_RS06445	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKU360_RS06450	COG1518	maintenance of DNA repeat elements
HKU360_RS06510	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HKU360_RS06510	COG1605	Chorismate mutase
HKU360_RS06530	COG2226	methyltransferase
HKU360_RS06540	COG3250	beta-galactosidase activity
HKU360_RS06545	COG2207	Transcriptional regulator
HKU360_RS06545	COG4753	response regulator
HKU360_RS06550	COG2972	Histidine kinase
HKU360_RS06560	COG1653	transport
HKU360_RS06565	COG0395	ABC-type sugar transport system, permease component
HKU360_RS06570	COG1175	transmembrane transport
HKU360_RS06580	COG2723	6-phospho-beta-galactosidase activity
HKU360_RS06585	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HKU360_RS06600	COG0383	alpha-mannosidase activity
HKU360_RS06695	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKU360_RS06700	COG1739	Uncharacterized protein family UPF0029
HKU360_RS06710	COG1098	S1 RNA binding domain
HKU360_RS06720	COG2197	response regulator
HKU360_RS06725	COG4585	Histidine kinase
HKU360_RS06735	COG2815	serine threonine protein kinase
HKU360_RS06735	COG0515	serine threonine protein kinase
HKU360_RS06745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKU360_RS06745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKU360_RS06755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKU360_RS06775	COG0583	DNA-binding transcription factor activity
HKU360_RS06780	COG0183	Belongs to the thiolase family
HKU360_RS06785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKU360_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
HKU360_RS06815	COG0116	Belongs to the methyltransferase superfamily
HKU360_RS06835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU360_RS06840	COG3579	cysteine-type endopeptidase activity
HKU360_RS06850	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKU360_RS06855	COG1113	amino acid transport
HKU360_RS06860	COG0492	ferredoxin-NADP+ reductase activity
HKU360_RS06870	COG1126	abc transporter atp-binding protein
HKU360_RS06880	COG0513	Belongs to the DEAD box helicase family
HKU360_RS06890	COG0768	penicillin binding
HKU360_RS06925	COG1131	(ABC) transporter
HKU360_RS06950	COG0446	pyridine nucleotide-disulphide oxidoreductase
HKU360_RS06955	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HKU360_RS06990	COG1755	Isoprenylcysteine carboxyl methyltransferase
HKU360_RS06995	COG0656	L-ascorbic acid biosynthetic process
HKU360_RS07005	COG1283	sodium-dependent phosphate transmembrane transporter activity
HKU360_RS07025	COG0561	phosphatase activity
HKU360_RS07030	COG2860	membrane
HKU360_RS07040	COG1105	Belongs to the carbohydrate kinase PfkB family
HKU360_RS07080	COG2217	Heavy metal translocating P-type atpase
HKU360_RS07110	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HKU360_RS07115	COG0195	Participates in both transcription termination and antitermination
HKU360_RS07135	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU360_RS07250	COG1783	phage Terminase large subunit
HKU360_RS07370	COG4974	Belongs to the 'phage' integrase family
HKU360_RS07390	COG4473	ABC transporter
HKU360_RS07395	COG1131	(ABC) transporter
HKU360_RS07400	COG0537	adenosine 5'-monophosphoramidase activity
HKU360_RS07410	COG1316	TRANSCRIPTIONal
HKU360_RS07420	COG0802	atpase or kinase
HKU360_RS07425	COG2252	PERMEase
HKU360_RS07430	COG0561	phosphatase activity
HKU360_RS07440	COG3715	PTS system
HKU360_RS07445	COG3716	PTS system mannose fructose sorbose family IID component
HKU360_RS07470	COG0439	Biotin carboxylase
HKU360_RS07485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HKU360_RS07490	COG1028	Short-chain dehydrogenase reductase Sdr
HKU360_RS07495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HKU360_RS07520	COG1024	Enoyl-CoA hydratase
HKU360_RS07525	COG0484	heat shock protein binding
HKU360_RS07555	COG0588	phosphoglycerate mutase activity
HKU360_RS07560	COG2261	transglycosylase associated protein
HKU360_RS07585	COG0574	Belongs to the PEP-utilizing enzyme family
HKU360_RS07585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKU360_RS07590	COG1335	isochorismatase
HKU360_RS07600	COG0436	Aminotransferase
HKU360_RS07610	COG0561	phosphatase activity
HKU360_RS07615	COG0252	asparaginase activity
HKU360_RS07630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKU360_RS07635	COG1129	ABC transporter
HKU360_RS07650	COG1132	(ABC) transporter
HKU360_RS07655	COG4988	ABC transporter
HKU360_RS07660	COG1120	ATPase activity
HKU360_RS07685	COG1388	LysM domain
HKU360_RS07685	COG3942	CHAP domain
HKU360_RS07710	COG5433	transposase activity
HKU360_RS07715	COG1482	cell wall glycoprotein biosynthetic process
HKU360_RS07720	COG1940	carbohydrate kinase activity
HKU360_RS07730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU360_RS07730	COG2190	(PTS) system
HKU360_RS07730	COG1263	PTS System
HKU360_RS07735	COG1621	beta-fructofuranosidase activity
HKU360_RS07740	COG1609	Transcriptional regulator
HKU360_RS07760	COG2131	deaminase
HKU360_RS07765	COG0006	proline dipeptidase activity
HKU360_RS07800	COG3177	Filamentation induced by cAMP protein fic
HKU360_RS07805	COG0860	N-Acetylmuramoyl-L-alanine amidase
HKU360_RS07805	COG1388	LysM domain
HKU360_RS07815	COG4824	toxin secretion phage lysis holin
HKU360_RS07985	COG3723	Recombinational DNA repair protein, rece pathway
HKU360_RS08005	COG3935	DnaD domain protein
HKU360_RS08035	COG3561	AntA/AntB antirepressor
HKU360_RS08125	COG1194	a g-specific adenine glycosylase
HKU360_RS08135	COG3118	belongs to the thioredoxin family
HKU360_RS08165	COG0681	Belongs to the peptidase S26 family
HKU360_RS08170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKU360_RS08185	COG1882	Formate acetyltransferase
HKU360_RS08190	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HKU360_RS08205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HKU360_RS08210	COG2814	Major facilitator Superfamily
HKU360_RS08215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKU360_RS08240	COG0789	Transcriptional regulator
HKU360_RS08255	COG2081	HI0933 family
HKU360_RS08265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKU360_RS08270	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HKU360_RS08290	COG0456	acetyltransferase
HKU360_RS08295	COG1214	PFAM Peptidase M22, glycoprotease
HKU360_RS08310	COG0174	glutamine synthetase
HKU360_RS08315	COG0789	Transcriptional regulator
HKU360_RS08330	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HKU360_RS08385	COG0668	transmembrane transport
HKU360_RS08395	COG4720	Psort location CytoplasmicMembrane, score
HKU360_RS08400	COG0351	phosphomethylpyrimidine kinase
HKU360_RS08445	COG1929	Belongs to the glycerate kinase type-1 family
HKU360_RS08450	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKU360_RS08480	COG0577	efflux transmembrane transporter activity
HKU360_RS08485	COG1136	(ABC) transporter
HKU360_RS08490	COG1132	(ABC) transporter
HKU360_RS08510	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU360_RS08510	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU360_RS08515	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU360_RS08565	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKU360_RS08570	COG1476	TRANSCRIPTIONal
HKU360_RS08590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKU360_RS08600	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKU360_RS08615	COG1045	serine acetyltransferase
HKU360_RS08630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKU360_RS08645	COG3711	transcriptional antiterminator
HKU360_RS08675	COG1846	Transcriptional regulator
HKU360_RS08695	COG4589	Belongs to the CDS family
HKU360_RS08705	COG1862	Preprotein translocase
HKU360_RS08715	COG1523	belongs to the glycosyl hydrolase 13 family
HKU360_RS08725	COG3842	ATPase activity
HKU360_RS08765	COG1263	PTS System
HKU360_RS08765	COG2190	(PTS) system
HKU360_RS08765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU360_RS08770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HKU360_RS08800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKU360_RS08805	COG0512	Glutamine amidotransferase of anthranilate synthase
HKU360_RS08810	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HKU360_RS08845	COG0601	transmembrane transport
HKU360_RS08875	COG0803	Belongs to the bacterial solute-binding protein 9 family
HKU360_RS08885	COG5433	transposase activity
HKU360_RS08890	COG1404	Belongs to the peptidase S8 family
HKU360_RS08890	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HKU360_RS08910	COG1196	nuclear chromosome segregation
HKU360_RS08915	COG3711	transcriptional antiterminator
HKU360_RS08925	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU360_RS08925	COG3942	CHAP domain
HKU360_RS08930	COG2205	protein histidine kinase activity
HKU360_RS08935	COG0745	RESPONSE REGULATOR receiver
HKU360_RS08940	COG0577	efflux transmembrane transporter activity
HKU360_RS08945	COG1136	(ABC) transporter
HKU360_RS09010	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HKU360_RS09025	COG1882	Formate acetyltransferase
HKU360_RS09030	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU360_RS09035	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU360_RS09040	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU360_RS09045	COG2390	Transcriptional regulator
HKU360_RS09050	COG1349	DNA-binding transcription factor activity
HKU360_RS09055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKU360_RS09070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU360_RS09085	COG0564	pseudouridine synthase activity
HKU360_RS09115	COG0542	response to heat
HKU360_RS09120	COG4463	regulation of RNA biosynthetic process
HKU360_RS09135	COG0450	alkyl hydroperoxide reductase
HKU360_RS09150	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKU360_RS09160	COG3404	Formiminotransferase-cyclodeaminase
HKU360_RS09175	COG0531	amino acid
HKU360_RS09205	COG3590	peptidase
HKU360_RS09210	COG0366	Alpha amylase catalytic
HKU360_RS09215	COG1263	PTS System
HKU360_RS09215	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU360_RS09220	COG2188	Transcriptional regulator
HKU360_RS09225	COG1733	regulation of RNA biosynthetic process
HKU360_RS09230	COG2514	catechol 2,3-dioxygenase activity
HKU360_RS09240	COG0602	queuosine metabolic process
HKU360_RS09250	COG0673	inositol 2-dehydrogenase activity
HKU360_RS09255	COG1328	CTP reductase activity
HKU360_RS09280	COG1393	Belongs to the ArsC family
HKU360_RS09295	COG0519	Catalyzes the synthesis of GMP from XMP
HKU360_RS09305	COG2814	Major facilitator Superfamily
HKU360_RS09340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU360_RS09345	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU360_RS09350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU360_RS09370	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HKU360_RS09430	COG1511	domain protein
HKU360_RS09450	COG0305	Participates in initiation and elongation during chromosome replication
HKU360_RS09480	COG1760	l-serine dehydratase
HKU360_RS09485	COG1760	l-serine dehydratase
HKU360_RS09490	COG0741	lytic transglycosylase activity
HKU360_RS09495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKU360_RS09510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKU360_RS09520	COG0612	Peptidase, M16
HKU360_RS09540	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HKU360_RS09560	COG0517	IMP dehydrogenase activity
HKU360_RS09560	COG0516	GMP reductase activity
HKU360_RS09570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU360_RS09575	COG0488	(ABC) transporter
HKU360_RS09610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKU360_RS09615	COG1475	DNA binding