locus-tag	class	description
HKU488_RS00010	COG0592	DNA-directed DNA polymerase activity
HKU488_RS00020	COG0012	GTP binding
HKU488_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKU488_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HKU488_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKU488_RS00065	COG0531	amino acid
HKU488_RS00240	COG3942	CHAP domain
HKU488_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKU488_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKU488_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKU488_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKU488_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKU488_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKU488_RS00350	COG1454	alcohol dehydrogenase
HKU488_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
HKU488_RS00355	COG1064	alcohol dehydrogenase
HKU488_RS00360	COG0534	Mate efflux family protein
HKU488_RS00470	COG0201	protein transport
HKU488_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HKU488_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU488_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKU488_RS00650	COG1459	type II secretion system
HKU488_RS00655	COG4537	Required for transformation and DNA binding
HKU488_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKU488_RS00700	COG1363	Peptidase, m42
HKU488_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKU488_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKU488_RS00725	COG1428	Deoxynucleoside kinase
HKU488_RS00730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKU488_RS00760	COG4509	Sortase family
HKU488_RS00770	COG4372	Transposase
HKU488_RS00795	COG2031	fatty acid transporter
HKU488_RS00815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKU488_RS00830	COG0251	oxidation-reduction process
HKU488_RS00845	COG1269	ATP hydrolysis coupled proton transport
HKU488_RS00850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKU488_RS00860	COG1527	subunit (C
HKU488_RS00865	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKU488_RS00900	COG1744	ABC transporter substrate-binding protein PnrA-like
HKU488_RS00940	COG0626	cystathionine gamma-synthase activity
HKU488_RS00970	COG3623	hexulose-6-phosphate isomerase
HKU488_RS00990	COG3448	diguanylate cyclase activity
HKU488_RS00990	COG4175	Glycine betaine
HKU488_RS01000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKU488_RS01000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKU488_RS01020	COG3969	phosphoadenosine phosphosulfate
HKU488_RS01025	COG1475	DNA binding
HKU488_RS01035	COG2801	Transposase and inactivated derivatives
HKU488_RS01040	COG2801	Transposase and inactivated derivatives
HKU488_RS01045	COG2801	Transposase and inactivated derivatives
HKU488_RS01060	COG0157	Belongs to the NadC ModD family
HKU488_RS01065	COG2801	Transposase and inactivated derivatives
HKU488_RS01085	COG1268	BioY protein
HKU488_RS01090	COG1234	tRNA 3'-trailer cleavage
HKU488_RS01120	COG5433	transposase activity
HKU488_RS01130	COG0803	Belongs to the bacterial solute-binding protein 9 family
HKU488_RS01150	COG1122	ATPase activity
HKU488_RS01160	COG0601	transmembrane transport
HKU488_RS01195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HKU488_RS01200	COG0512	Glutamine amidotransferase of anthranilate synthase
HKU488_RS01205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKU488_RS01220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HKU488_RS01225	COG2190	(PTS) system
HKU488_RS01225	COG1263	PTS System
HKU488_RS01225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU488_RS01265	COG3842	ATPase activity
HKU488_RS01275	COG1523	belongs to the glycosyl hydrolase 13 family
HKU488_RS01285	COG1862	Preprotein translocase
HKU488_RS01295	COG4589	Belongs to the CDS family
HKU488_RS01315	COG1846	Transcriptional regulator
HKU488_RS01340	COG3711	transcriptional antiterminator
HKU488_RS01350	COG3037	sugar-specific permease SgaT UlaA
HKU488_RS01355	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKU488_RS01370	COG1045	serine acetyltransferase
HKU488_RS01385	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKU488_RS01395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKU488_RS01415	COG1476	TRANSCRIPTIONal
HKU488_RS01420	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKU488_RS01470	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU488_RS01475	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU488_RS01475	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU488_RS01500	COG1136	(ABC) transporter
HKU488_RS01505	COG0577	efflux transmembrane transporter activity
HKU488_RS01535	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HKU488_RS01540	COG1929	Belongs to the glycerate kinase type-1 family
HKU488_RS01580	COG5433	transposase activity
HKU488_RS01595	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HKU488_RS01600	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKU488_RS01605	COG1534	Rna-binding protein
HKU488_RS01615	COG1713	HD superfamily hydrolase involved in NAD metabolism
HKU488_RS01620	COG0799	negative regulation of ribosome biogenesis
HKU488_RS01625	COG2226	methyltransferase
HKU488_RS01640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU488_RS01645	COG1464	Belongs to the NlpA lipoprotein family
HKU488_RS01660	COG1114	Component of the transport system for branched-chain amino acids
HKU488_RS01670	COG0569	domain protein
HKU488_RS01675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HKU488_RS01685	COG1704	LemA family
HKU488_RS01700	COG0745	RESPONSE REGULATOR receiver
HKU488_RS01720	COG1484	DNA-dependent DNA replication
HKU488_RS01730	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HKU488_RS01750	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKU488_RS01765	COG1254	Belongs to the acylphosphatase family
HKU488_RS01780	COG5433	transposase activity
HKU488_RS01785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKU488_RS01840	COG1187	pseudouridine synthase activity
HKU488_RS01855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKU488_RS01860	COG0671	phosphoesterase, PA-phosphatase related
HKU488_RS01865	COG1242	4 iron, 4 sulfur cluster binding
HKU488_RS01870	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HKU488_RS01875	COG1253	flavin adenine dinucleotide binding
HKU488_RS01880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKU488_RS01895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKU488_RS01900	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKU488_RS01905	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HKU488_RS01910	COG1120	ATPase activity
HKU488_RS01920	COG2244	polysaccharide biosynthetic process
HKU488_RS01945	COG0470	DNA polymerase III
HKU488_RS01980	COG1393	Belongs to the ArsC family
HKU488_RS01985	COG0708	Exodeoxyribonuclease III
HKU488_RS01995	COG1304	FMN binding
HKU488_RS02075	COG1028	Short-chain dehydrogenase reductase Sdr
HKU488_RS02080	COG0673	inositol 2-dehydrogenase activity
HKU488_RS02095	COG0494	nUDIX hydrolase
HKU488_RS02105	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKU488_RS02195	COG1702	phosphate starvation-inducible protein PhoH
HKU488_RS02200	COG1573	uracil-dna glycosylase
HKU488_RS02210	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HKU488_RS02290	COG0433	COG0433 Predicted ATPase
HKU488_RS02295	COG2814	Major facilitator Superfamily
HKU488_RS02305	COG0557	exoribonuclease II activity
HKU488_RS02335	COG0463	Glycosyl transferase, family 2
HKU488_RS02345	COG0778	Nitroreductase
HKU488_RS02350	COG0006	proline dipeptidase activity
HKU488_RS02355	COG1609	Transcriptional regulator
HKU488_RS02365	COG0438	transferase activity, transferring glycosyl groups
HKU488_RS02375	COG4555	ABC transporter
HKU488_RS02395	COG0183	Belongs to the thiolase family
HKU488_RS02410	COG0745	RESPONSE REGULATOR receiver
HKU488_RS02415	COG5002	protein histidine kinase activity
HKU488_RS02420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
HKU488_RS02430	COG1196	nuclear chromosome segregation
HKU488_RS02440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKU488_RS02520	COG4695	Portal protein
HKU488_RS02570	COG0561	phosphatase activity
HKU488_RS02575	COG0561	phosphatase activity
HKU488_RS02580	COG0552	protein localization to endoplasmic reticulum
HKU488_RS02585	COG0477	Major facilitator Superfamily
HKU488_RS02590	COG3711	transcriptional antiterminator
HKU488_RS02595	COG1263	PTS System
HKU488_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU488_RS02595	COG2190	(PTS) system
HKU488_RS02605	COG3689	TIGRFAM TIGR03943 family protein
HKU488_RS02610	COG0701	Predicted permease
HKU488_RS02620	COG2183	response to ionizing radiation
HKU488_RS02665	COG0826	peptidase U32
HKU488_RS02670	COG4443	Transcriptional Coactivator p15 (PC4)
HKU488_RS02720	COG0386	Belongs to the glutathione peroxidase family
HKU488_RS02725	COG1164	Oligoendopeptidase f
HKU488_RS02735	COG0772	Belongs to the SEDS family
HKU488_RS02770	COG1078	dGTPase activity
HKU488_RS02785	COG1609	Transcriptional regulator
HKU488_RS02795	COG3716	PTS system mannose fructose sorbose family IID component
HKU488_RS02800	COG3715	PTS system
HKU488_RS02805	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU488_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
HKU488_RS02835	COG0800	Aldolase
HKU488_RS02840	COG0546	phosphoglycolate phosphatase activity
HKU488_RS02845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKU488_RS02855	COG2884	Cell division ATP-binding protein ftsE
HKU488_RS02860	COG2177	Part of the ABC transporter FtsEX involved in
HKU488_RS02875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKU488_RS02875	COG1199	ATP-dependent helicase activity
HKU488_RS02880	COG0436	Aminotransferase
HKU488_RS02915	COG2188	Transcriptional regulator
HKU488_RS02920	COG2222	sugar isomerase
HKU488_RS02930	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HKU488_RS02935	COG0716	FMN binding
HKU488_RS02945	COG0038	chloride channel
HKU488_RS03035	COG1131	(ABC) transporter
HKU488_RS03055	COG4708	membrane
HKU488_RS03065	COG1597	lipid kinase activity
HKU488_RS03150	COG0577	efflux transmembrane transporter activity
HKU488_RS03160	COG2321	neutral zinc metallopeptidase
HKU488_RS03175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU488_RS03185	COG1970	mechanosensitive ion channel activity
HKU488_RS03190	COG0358	DNA primase activity
HKU488_RS03195	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKU488_RS03200	COG2151	metal-sulfur cluster biosynthetic enzyme
HKU488_RS03245	COG1216	Glycosyl transferase, family 2
HKU488_RS03300	COG1368	sulfuric ester hydrolase activity
HKU488_RS03305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HKU488_RS03325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HKU488_RS03330	COG0285	dihydrofolate synthase activity
HKU488_RS03340	COG1104	cysteine desulfurase activity
HKU488_RS03365	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HKU488_RS03370	COG0583	DNA-binding transcription factor activity
HKU488_RS03380	COG0564	pseudouridine synthase activity
HKU488_RS03410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKU488_RS03415	COG1136	(ABC) transporter
HKU488_RS03420	COG0577	efflux transmembrane transporter activity
HKU488_RS03425	COG0584	glycerophosphoryl diester phosphodiesterase
HKU488_RS03435	COG1837	Belongs to the UPF0109 family
HKU488_RS03485	COG1349	DNA-binding transcription factor activity
HKU488_RS03490	COG1105	Belongs to the carbohydrate kinase PfkB family
HKU488_RS03495	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HKU488_RS03495	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HKU488_RS03495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKU488_RS03500	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU488_RS03500	COG1388	LysM domain
HKU488_RS03505	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU488_RS03505	COG1388	LysM domain
HKU488_RS03510	COG2801	Transposase and inactivated derivatives
HKU488_RS03525	COG0105	UTP biosynthetic process
HKU488_RS03545	COG0488	(ABC) transporter
HKU488_RS03555	COG0242	peptide deformylase activity
HKU488_RS03560	COG0737	Belongs to the 5'-nucleotidase family
HKU488_RS03565	COG2357	RelA SpoT domain protein
HKU488_RS03570	COG0745	RESPONSE REGULATOR receiver
HKU488_RS03605	COG3425	synthase
HKU488_RS03615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKU488_RS03675	COG0583	DNA-binding transcription factor activity
HKU488_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU488_RS03705	COG0765	amino acid transport
HKU488_RS03725	COG0187	DNA topoisomerase II activity
HKU488_RS03735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HKU488_RS03755	COG0539	negative regulation of cytoplasmic translation
HKU488_RS03790	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKU488_RS03795	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
HKU488_RS03805	COG0300	oxidoreductase activity
HKU488_RS03810	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HKU488_RS03810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HKU488_RS03825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKU488_RS03830	COG2384	SAM-dependent methyltransferase
HKU488_RS03840	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HKU488_RS03845	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKU488_RS03855	COG1088	dTDP-glucose 4,6-dehydratase activity
HKU488_RS03860	COG1051	belongs to the nudix hydrolase family
HKU488_RS03865	COG0628	permease
HKU488_RS03870	COG0457	Tetratricopeptide repeat
HKU488_RS03875	COG1293	RNA-binding protein homologous to eukaryotic snRNP
HKU488_RS03890	COG1129	ABC transporter
HKU488_RS03910	COG0488	(ABC) transporter
HKU488_RS03915	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HKU488_RS03920	COG0508	dehydrogenase complex catalyzes the overall conversion of
HKU488_RS03920	COG0022	dehydrogenase e1 component
HKU488_RS03940	COG5492	domain, Protein
HKU488_RS03945	COG0095	Lipoate-protein ligase
HKU488_RS03950	COG3442	glutamine amidotransferase
HKU488_RS03955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKU488_RS03960	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKU488_RS03980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HKU488_RS03990	COG0647	UMP catabolic process
HKU488_RS04005	COG1518	maintenance of DNA repeat elements
HKU488_RS04010	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKU488_RS04025	COG0105	UTP biosynthetic process
HKU488_RS04060	COG3715	PTS system
HKU488_RS04065	COG3716	PTS system mannose fructose sorbose family IID component
HKU488_RS04070	COG2972	Histidine kinase
HKU488_RS04075	COG2207	Transcriptional regulator
HKU488_RS04075	COG4753	response regulator
HKU488_RS04080	COG1840	ABC-type Fe3 transport system, periplasmic component
HKU488_RS04095	COG1011	Hydrolase
HKU488_RS04100	COG1012	belongs to the aldehyde dehydrogenase family
HKU488_RS04115	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKU488_RS04175	COG1131	(ABC) transporter
HKU488_RS04190	COG1396	sequence-specific DNA binding
HKU488_RS04225	COG0285	dihydrofolate synthase activity
HKU488_RS04245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKU488_RS04260	COG1176	ABC-type spermidine putrescine transport system, permease component I
HKU488_RS04265	COG1177	transmembrane transport
HKU488_RS04275	COG4565	transcriptional regulatory protein
HKU488_RS04280	COG3290	protein histidine kinase activity
HKU488_RS04285	COG3493	citrate carrier protein
HKU488_RS04300	COG3700	Belongs to the class B bacterial acid phosphatase family
HKU488_RS04305	COG0038	chloride channel
HKU488_RS04315	COG0628	permease
HKU488_RS04325	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HKU488_RS04340	COG1104	cysteine desulfurase activity
HKU488_RS04355	COG2357	RelA SpoT domain protein
HKU488_RS04365	COG0564	pseudouridine synthase activity
HKU488_RS04370	COG0280	phosphate acetyltransferase
HKU488_RS04390	COG1174	glycine betaine transport
HKU488_RS04405	COG2233	PERMEase
HKU488_RS04430	COG2890	protein-(glutamine-N5) methyltransferase activity
HKU488_RS04460	COG1132	(ABC) transporter
HKU488_RS04465	COG1132	(ABC) transporter
HKU488_RS04485	COG3764	Sortase (surface protein transpeptidase)
HKU488_RS04490	COG0346	lactoylglutathione lyase activity
HKU488_RS04505	COG1272	protein, Hemolysin III
HKU488_RS04525	COG0758	DNA mediated transformation
HKU488_RS04530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKU488_RS04575	COG0511	ligase activity, forming carbon-carbon bonds
HKU488_RS04580	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HKU488_RS04595	COG2851	Citrate transporter
HKU488_RS04605	COG0511	ligase activity, forming carbon-carbon bonds
HKU488_RS04610	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HKU488_RS04645	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKU488_RS04665	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKU488_RS04675	COG2188	Transcriptional regulator
HKU488_RS04695	COG0488	(ABC) transporter
HKU488_RS04705	COG0352	thiamine-phosphate diphosphorylase activity
HKU488_RS04705	COG0351	phosphomethylpyrimidine kinase
HKU488_RS04710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HKU488_RS04715	COG1328	CTP reductase activity
HKU488_RS04715	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKU488_RS04720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKU488_RS04750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKU488_RS04770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKU488_RS04775	COG4684	Psort location CytoplasmicMembrane, score
HKU488_RS04780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKU488_RS04785	COG1079	Belongs to the binding-protein-dependent transport system permease family
HKU488_RS04790	COG4603	Belongs to the binding-protein-dependent transport system permease family
HKU488_RS04795	COG3845	ABC transporter
HKU488_RS04800	COG1744	ABC transporter substrate-binding protein PnrA-like
HKU488_RS04805	COG0295	cytidine deaminase activity
HKU488_RS04810	COG2813	Specifically methylates the guanine in position
HKU488_RS04825	COG5002	protein histidine kinase activity
HKU488_RS04830	COG0745	RESPONSE REGULATOR receiver
HKU488_RS04840	COG0704	Plays a role in the regulation of phosphate uptake
HKU488_RS04855	COG0581	inorganic phosphate transmembrane transporter activity
HKU488_RS04860	COG0573	inorganic phosphate transmembrane transporter activity
HKU488_RS04870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKU488_RS04870	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
HKU488_RS04875	COG0483	inositol monophosphate 1-phosphatase activity
HKU488_RS04890	COG0196	riboflavin kinase activity
HKU488_RS04920	COG1136	(ABC) transporter
HKU488_RS04920	COG4591	ABC-type transport system involved in lipoprotein release permease component
HKU488_RS04970	COG1115	amino acid carrier protein
HKU488_RS04975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKU488_RS04985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU488_RS04990	COG1126	abc transporter atp-binding protein
HKU488_RS04995	COG0765	amino acid transport
HKU488_RS05000	COG2824	Alkylphosphonate utilization operon protein PhnA
HKU488_RS05015	COG0469	pyruvate kinase activity
HKU488_RS05030	COG1725	Transcriptional regulator
HKU488_RS05035	COG1131	(ABC) transporter
HKU488_RS05190	COG1783	phage Terminase large subunit
HKU488_RS05295	COG1396	sequence-specific DNA binding
HKU488_RS05335	COG0058	SHG alpha-glucan phosphorylase activity
HKU488_RS05340	COG1640	4-alpha-glucanotransferase
HKU488_RS05345	COG1609	Transcriptional regulator
HKU488_RS05350	COG2182	Extracellular solute-binding protein
HKU488_RS05355	COG1175	transmembrane transport
HKU488_RS05360	COG3833	ABC-type maltose transport systems, permease component
HKU488_RS05375	COG3833	ABC-type maltose transport systems, permease component
HKU488_RS05380	COG1175	transmembrane transport
HKU488_RS05390	COG0366	Alpha amylase catalytic
HKU488_RS05395	COG2182	Extracellular solute-binding protein
HKU488_RS05405	COG0657	acetylesterase activity
HKU488_RS05410	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKU488_RS05420	COG1696	Membrane protein involved in D-alanine export
HKU488_RS05440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HKU488_RS05445	COG1126	abc transporter atp-binding protein
HKU488_RS05450	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU488_RS05460	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU488_RS05470	COG3711	transcriptional antiterminator
HKU488_RS05470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HKU488_RS05480	COG2723	6-phospho-beta-galactosidase activity
HKU488_RS05505	COG2801	Transposase and inactivated derivatives
HKU488_RS05510	COG1187	pseudouridine synthase activity
HKU488_RS05520	COG2814	Major facilitator Superfamily
HKU488_RS05560	COG1132	(ABC) transporter
HKU488_RS05565	COG1132	(ABC) transporter
HKU488_RS05565	COG2375	cellular response to nickel ion
HKU488_RS05600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKU488_RS05610	COG0791	NLP P60 protein
HKU488_RS05610	COG0741	lytic transglycosylase activity
HKU488_RS05655	COG2946	Replication initiation factor
HKU488_RS05660	COG1674	ftsk spoiiie
HKU488_RS05675	COG1129	ABC transporter
HKU488_RS05690	COG1309	transcriptional regulator
HKU488_RS05725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKU488_RS05725	COG0551	DNA topoisomerase type I activity
HKU488_RS05785	COG1484	DNA-dependent DNA replication
HKU488_RS05830	COG4109	DRTGG domain
HKU488_RS05860	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HKU488_RS05860	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HKU488_RS05865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKU488_RS05870	COG1956	GAF domain-containing protein
HKU488_RS05890	COG0513	Belongs to the DEAD box helicase family
HKU488_RS05895	COG0726	polysaccharide deacetylase
HKU488_RS05915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HKU488_RS05920	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKU488_RS05925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKU488_RS05940	COG2801	Transposase and inactivated derivatives
HKU488_RS05950	COG2801	Transposase and inactivated derivatives
HKU488_RS05965	COG1476	TRANSCRIPTIONal
HKU488_RS05980	COG4122	O-methyltransferase activity
HKU488_RS05985	COG2223	nitrite transmembrane transporter activity
HKU488_RS06000	COG1187	pseudouridine synthase activity
HKU488_RS06045	COG0658	competence protein
HKU488_RS06045	COG2333	competence protein COMEC
HKU488_RS06050	COG1555	photosystem II stabilization
HKU488_RS06050	COG1596	polysaccharide export
HKU488_RS06055	COG0204	Acyl-transferase
HKU488_RS06060	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HKU488_RS06075	COG0513	Belongs to the DEAD box helicase family
HKU488_RS06090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HKU488_RS06105	COG0768	penicillin binding
HKU488_RS06110	COG2116	formate transmembrane transporter activity
HKU488_RS06120	COG1827	regulation of RNA biosynthetic process
HKU488_RS06135	COG2217	Heavy metal translocating P-type atpase
HKU488_RS06320	COG3723	Recombinational DNA repair protein, rece pathway
HKU488_RS06340	COG3935	DnaD domain protein
HKU488_RS06375	COG3561	AntA/AntB antirepressor
HKU488_RS06385	COG1396	sequence-specific DNA binding
HKU488_RS06400	COG0582	viral genome integration into host DNA
HKU488_RS06415	COG2755	lipolytic protein G-D-S-L family
HKU488_RS06430	COG0497	DNA recombination
HKU488_RS06435	COG1438	arginine binding
HKU488_RS06440	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HKU488_RS06465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKU488_RS06470	COG0415	Belongs to the DNA photolyase family
HKU488_RS06480	COG0765	amino acid transport
HKU488_RS06485	COG4703	Protein of unknown function (DUF1797)
HKU488_RS06490	COG0542	response to heat
HKU488_RS06495	COG0494	nUDIX hydrolase
HKU488_RS06510	COG3599	regulation of cell shape
HKU488_RS06515	COG2302	S4 RNA-binding domain
HKU488_RS06530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKU488_RS06565	COG1217	gtp-binding protein TYPA
HKU488_RS06570	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKU488_RS06575	COG1940	carbohydrate kinase activity
HKU488_RS06585	COG0783	Belongs to the Dps family
HKU488_RS06600	COG4470	Protein conserved in bacteria
HKU488_RS06610	COG3480	Lon protease (S16) C-terminal proteolytic domain
HKU488_RS06620	COG0742	ribosomal rna small subunit methyltransferase
HKU488_RS06630	COG0549	Belongs to the carbamate kinase family
HKU488_RS06635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HKU488_RS06640	COG1288	antiporter activity
HKU488_RS06655	COG2235	arginine
HKU488_RS06680	COG2972	Histidine kinase
HKU488_RS06695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HKU488_RS06700	COG0785	Cytochrome C biogenesis protein
HKU488_RS06705	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKU488_RS06710	COG1518	maintenance of DNA repeat elements
HKU488_RS06770	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HKU488_RS06770	COG1605	Chorismate mutase
HKU488_RS06790	COG2226	methyltransferase
HKU488_RS06800	COG3250	beta-galactosidase activity
HKU488_RS06805	COG2207	Transcriptional regulator
HKU488_RS06805	COG4753	response regulator
HKU488_RS06810	COG2972	Histidine kinase
HKU488_RS06820	COG1653	transport
HKU488_RS06825	COG0395	ABC-type sugar transport system, permease component
HKU488_RS06830	COG1175	transmembrane transport
HKU488_RS06835	COG1940	carbohydrate kinase activity
HKU488_RS06840	COG2723	6-phospho-beta-galactosidase activity
HKU488_RS06845	COG3525	Glycosyl hydrolase, family 20, catalytic domain
HKU488_RS06860	COG0383	alpha-mannosidase activity
HKU488_RS06950	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKU488_RS06955	COG1739	Uncharacterized protein family UPF0029
HKU488_RS06965	COG1098	S1 RNA binding domain
HKU488_RS06975	COG2197	response regulator
HKU488_RS06980	COG4585	Histidine kinase
HKU488_RS06990	COG0515	serine threonine protein kinase
HKU488_RS06990	COG2815	serine threonine protein kinase
HKU488_RS07000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKU488_RS07000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKU488_RS07010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKU488_RS07030	COG0583	DNA-binding transcription factor activity
HKU488_RS07035	COG0183	Belongs to the thiolase family
HKU488_RS07040	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKU488_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
HKU488_RS07055	COG2610	gluconate transmembrane transporter activity
HKU488_RS07070	COG0116	Belongs to the methyltransferase superfamily
HKU488_RS07090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU488_RS07095	COG3579	cysteine-type endopeptidase activity
HKU488_RS07105	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKU488_RS07110	COG1113	amino acid transport
HKU488_RS07115	COG0492	ferredoxin-NADP+ reductase activity
HKU488_RS07125	COG1126	abc transporter atp-binding protein
HKU488_RS07135	COG0513	Belongs to the DEAD box helicase family
HKU488_RS07145	COG0768	penicillin binding
HKU488_RS07185	COG1131	(ABC) transporter
HKU488_RS07210	COG0446	pyridine nucleotide-disulphide oxidoreductase
HKU488_RS07215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HKU488_RS07250	COG1755	Isoprenylcysteine carboxyl methyltransferase
HKU488_RS07255	COG0656	L-ascorbic acid biosynthetic process
HKU488_RS07265	COG1283	sodium-dependent phosphate transmembrane transporter activity
HKU488_RS07285	COG0561	phosphatase activity
HKU488_RS07290	COG2860	membrane
HKU488_RS07340	COG2217	Heavy metal translocating P-type atpase
HKU488_RS07370	COG2740	Nucleic-acid-binding protein implicated in transcription termination
HKU488_RS07375	COG0195	Participates in both transcription termination and antitermination
HKU488_RS07395	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU488_RS07515	COG1783	phage Terminase large subunit
HKU488_RS07630	COG4974	Belongs to the 'phage' integrase family
HKU488_RS07650	COG4473	ABC transporter
HKU488_RS07655	COG1131	(ABC) transporter
HKU488_RS07660	COG0537	adenosine 5'-monophosphoramidase activity
HKU488_RS07670	COG1316	TRANSCRIPTIONal
HKU488_RS07680	COG0802	atpase or kinase
HKU488_RS07685	COG2252	PERMEase
HKU488_RS07690	COG0561	phosphatase activity
HKU488_RS07700	COG3715	PTS system
HKU488_RS07705	COG3716	PTS system mannose fructose sorbose family IID component
HKU488_RS07730	COG0439	Biotin carboxylase
HKU488_RS07745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HKU488_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
HKU488_RS07755	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HKU488_RS07780	COG1024	Enoyl-CoA hydratase
HKU488_RS07815	COG0588	phosphoglycerate mutase activity
HKU488_RS07820	COG2261	transglycosylase associated protein
HKU488_RS07845	COG0574	Belongs to the PEP-utilizing enzyme family
HKU488_RS07845	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKU488_RS07850	COG1335	isochorismatase
HKU488_RS07860	COG0436	Aminotransferase
HKU488_RS07870	COG0561	phosphatase activity
HKU488_RS07875	COG0252	asparaginase activity
HKU488_RS07890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKU488_RS07895	COG1129	ABC transporter
HKU488_RS07910	COG1132	(ABC) transporter
HKU488_RS07915	COG4988	ABC transporter
HKU488_RS07920	COG1120	ATPase activity
HKU488_RS07945	COG3942	CHAP domain
HKU488_RS07945	COG1388	LysM domain
HKU488_RS07970	COG5433	transposase activity
HKU488_RS07975	COG1482	cell wall glycoprotein biosynthetic process
HKU488_RS07980	COG1940	carbohydrate kinase activity
HKU488_RS07990	COG1263	PTS System
HKU488_RS07990	COG2190	(PTS) system
HKU488_RS07990	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU488_RS07995	COG1621	beta-fructofuranosidase activity
HKU488_RS08000	COG1609	Transcriptional regulator
HKU488_RS08020	COG2131	deaminase
HKU488_RS08025	COG0006	proline dipeptidase activity
HKU488_RS08060	COG3177	Filamentation induced by cAMP protein fic
HKU488_RS08065	COG0860	N-Acetylmuramoyl-L-alanine amidase
HKU488_RS08065	COG1388	LysM domain
HKU488_RS08075	COG4824	toxin secretion phage lysis holin
HKU488_RS08245	COG3723	Recombinational DNA repair protein, rece pathway
HKU488_RS08265	COG3935	DnaD domain protein
HKU488_RS08295	COG3561	AntA/AntB antirepressor
HKU488_RS08385	COG1194	a g-specific adenine glycosylase
HKU488_RS08395	COG3118	belongs to the thioredoxin family
HKU488_RS08425	COG0681	Belongs to the peptidase S26 family
HKU488_RS08430	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HKU488_RS08445	COG1882	Formate acetyltransferase
HKU488_RS08450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HKU488_RS08465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HKU488_RS08470	COG2814	Major facilitator Superfamily
HKU488_RS08475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HKU488_RS08500	COG0789	Transcriptional regulator
HKU488_RS08515	COG2081	HI0933 family
HKU488_RS08525	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKU488_RS08530	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HKU488_RS08550	COG0456	acetyltransferase
HKU488_RS08555	COG1214	PFAM Peptidase M22, glycoprotease
HKU488_RS08570	COG0174	glutamine synthetase
HKU488_RS08575	COG0789	Transcriptional regulator
HKU488_RS08590	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
HKU488_RS08615	COG5433	transposase activity
HKU488_RS08655	COG0668	transmembrane transport
HKU488_RS08665	COG4720	Psort location CytoplasmicMembrane, score
HKU488_RS08670	COG0351	phosphomethylpyrimidine kinase
HKU488_RS08725	COG0444	Belongs to the ABC transporter superfamily
HKU488_RS08730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKU488_RS08735	COG0601	transmembrane transport
HKU488_RS08740	COG4166	transmembrane transport
HKU488_RS08745	COG1686	Belongs to the peptidase S11 family
HKU488_RS08750	COG1686	Belongs to the peptidase S11 family
HKU488_RS08765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKU488_RS08770	COG0719	Fe-S assembly protein
HKU488_RS08780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKU488_RS08800	COG0765	amino acid transport
HKU488_RS08835	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKU488_RS08850	COG1564	THIamine pyrophosphokinase
HKU488_RS08875	COG0084	hydrolase, TatD family'
HKU488_RS08890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKU488_RS08900	COG0395	ABC-type sugar transport system, permease component
HKU488_RS08905	COG1175	transmembrane transport
HKU488_RS08925	COG1847	R3H domain protein
HKU488_RS08950	COG3290	protein histidine kinase activity
HKU488_RS08975	COG0756	dUTP diphosphatase activity
HKU488_RS08985	COG1132	(ABC) transporter
HKU488_RS08990	COG1132	(ABC) transporter
HKU488_RS09010	COG0457	Tetratricopeptide repeat
HKU488_RS09010	COG0705	Rhomboid family
HKU488_RS09020	COG5433	transposase activity
HKU488_RS09050	COG3711	transcriptional antiterminator
HKU488_RS09060	COG3942	CHAP domain
HKU488_RS09060	COG1705	Flagellar rod assembly protein muramidase FlgJ
HKU488_RS09065	COG2205	protein histidine kinase activity
HKU488_RS09070	COG0745	RESPONSE REGULATOR receiver
HKU488_RS09075	COG0577	efflux transmembrane transporter activity
HKU488_RS09080	COG1136	(ABC) transporter
HKU488_RS09130	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HKU488_RS09145	COG1882	Formate acetyltransferase
HKU488_RS09150	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU488_RS09155	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKU488_RS09160	COG1447	Phosphotransferase system cellobiose-specific component IIA
HKU488_RS09165	COG2390	Transcriptional regulator
HKU488_RS09170	COG1349	DNA-binding transcription factor activity
HKU488_RS09175	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKU488_RS09190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HKU488_RS09205	COG0564	pseudouridine synthase activity
HKU488_RS09235	COG0542	response to heat
HKU488_RS09240	COG4463	regulation of RNA biosynthetic process
HKU488_RS09255	COG0450	alkyl hydroperoxide reductase
HKU488_RS09270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKU488_RS09280	COG3404	Formiminotransferase-cyclodeaminase
HKU488_RS09295	COG0531	amino acid
HKU488_RS09325	COG3590	peptidase
HKU488_RS09330	COG0366	Alpha amylase catalytic
HKU488_RS09335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HKU488_RS09335	COG1263	PTS System
HKU488_RS09340	COG2188	Transcriptional regulator
HKU488_RS09350	COG2514	catechol 2,3-dioxygenase activity
HKU488_RS09360	COG0602	queuosine metabolic process
HKU488_RS09375	COG1328	CTP reductase activity
HKU488_RS09400	COG1393	Belongs to the ArsC family
HKU488_RS09415	COG0519	Catalyzes the synthesis of GMP from XMP
HKU488_RS09425	COG2814	Major facilitator Superfamily
HKU488_RS09460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU488_RS09465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU488_RS09470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU488_RS09550	COG1511	domain protein
HKU488_RS09570	COG5433	transposase activity
HKU488_RS09580	COG0305	Participates in initiation and elongation during chromosome replication
HKU488_RS09610	COG1760	l-serine dehydratase
HKU488_RS09615	COG1760	l-serine dehydratase
HKU488_RS09620	COG0741	lytic transglycosylase activity
HKU488_RS09625	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKU488_RS09640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKU488_RS09650	COG0612	Peptidase, M16
HKU488_RS09660	COG1215	transferase activity, transferring glycosyl groups
HKU488_RS09690	COG0517	IMP dehydrogenase activity
HKU488_RS09690	COG0516	GMP reductase activity
HKU488_RS09700	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKU488_RS09705	COG0488	(ABC) transporter
HKU488_RS09745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKU488_RS09750	COG1475	DNA binding