locus-tag	class	description
CRD75_RS00010	COG0592	DNA-directed DNA polymerase activity
CRD75_RS00020	COG0012	GTP binding
CRD75_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CRD75_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CRD75_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CRD75_RS00065	COG0531	amino acid
CRD75_RS00240	COG3942	CHAP domain
CRD75_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CRD75_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CRD75_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CRD75_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CRD75_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CRD75_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CRD75_RS00350	COG1454	alcohol dehydrogenase
CRD75_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
CRD75_RS00355	COG1064	alcohol dehydrogenase
CRD75_RS00360	COG0534	Mate efflux family protein
CRD75_RS00470	COG0201	protein transport
CRD75_RS00615	COG1121	(ABC) transporter
CRD75_RS00620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CRD75_RS00635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRD75_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CRD75_RS00660	COG1459	type II secretion system
CRD75_RS00665	COG4537	Required for transformation and DNA binding
CRD75_RS00705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CRD75_RS00710	COG1363	Peptidase, m42
CRD75_RS00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRD75_RS00730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CRD75_RS00740	COG1428	Deoxynucleoside kinase
CRD75_RS00745	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CRD75_RS00790	COG4509	Sortase family
CRD75_RS00815	COG2031	fatty acid transporter
CRD75_RS00830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRD75_RS00845	COG0251	oxidation-reduction process
CRD75_RS00860	COG1269	ATP hydrolysis coupled proton transport
CRD75_RS00865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CRD75_RS00875	COG1527	subunit (C
CRD75_RS00880	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
CRD75_RS00915	COG1744	ABC transporter substrate-binding protein PnrA-like
CRD75_RS00960	COG0626	cystathionine gamma-synthase activity
CRD75_RS00990	COG3623	hexulose-6-phosphate isomerase
CRD75_RS01015	COG4175	Glycine betaine
CRD75_RS01015	COG3448	diguanylate cyclase activity
CRD75_RS01025	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRD75_RS01025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CRD75_RS01045	COG3969	phosphoadenosine phosphosulfate
CRD75_RS01050	COG1475	DNA binding
CRD75_RS01060	COG2801	Transposase and inactivated derivatives
CRD75_RS01105	COG1268	BioY protein
CRD75_RS01110	COG1234	tRNA 3'-trailer cleavage
CRD75_RS01145	COG0457	Tetratricopeptide repeat
CRD75_RS01145	COG0705	Rhomboid family
CRD75_RS01165	COG1132	(ABC) transporter
CRD75_RS01170	COG1132	(ABC) transporter
CRD75_RS01180	COG0756	dUTP diphosphatase activity
CRD75_RS01205	COG3290	protein histidine kinase activity
CRD75_RS01230	COG1847	R3H domain protein
CRD75_RS01250	COG1175	transmembrane transport
CRD75_RS01255	COG0395	ABC-type sugar transport system, permease component
CRD75_RS01265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CRD75_RS01280	COG0084	hydrolase, TatD family'
CRD75_RS01305	COG1564	THIamine pyrophosphokinase
CRD75_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CRD75_RS01360	COG0765	amino acid transport
CRD75_RS01380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CRD75_RS01390	COG0719	Fe-S assembly protein
CRD75_RS01395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CRD75_RS01410	COG1686	Belongs to the peptidase S11 family
CRD75_RS01415	COG1686	Belongs to the peptidase S11 family
CRD75_RS01420	COG4166	transmembrane transport
CRD75_RS01425	COG0601	transmembrane transport
CRD75_RS01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CRD75_RS01435	COG0444	Belongs to the ABC transporter superfamily
CRD75_RS01485	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
CRD75_RS01490	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CRD75_RS01495	COG1534	Rna-binding protein
CRD75_RS01505	COG1713	HD superfamily hydrolase involved in NAD metabolism
CRD75_RS01510	COG0799	negative regulation of ribosome biogenesis
CRD75_RS01515	COG2226	methyltransferase
CRD75_RS01535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRD75_RS01540	COG1464	Belongs to the NlpA lipoprotein family
CRD75_RS01555	COG1114	Component of the transport system for branched-chain amino acids
CRD75_RS01565	COG0569	domain protein
CRD75_RS01570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CRD75_RS01580	COG1704	LemA family
CRD75_RS01595	COG0745	RESPONSE REGULATOR receiver
CRD75_RS01615	COG1484	DNA-dependent DNA replication
CRD75_RS01625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CRD75_RS01645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CRD75_RS01660	COG1254	Belongs to the acylphosphatase family
CRD75_RS01665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRD75_RS01720	COG1187	pseudouridine synthase activity
CRD75_RS01735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CRD75_RS01740	COG0671	phosphoesterase, PA-phosphatase related
CRD75_RS01745	COG1242	4 iron, 4 sulfur cluster binding
CRD75_RS01750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CRD75_RS01755	COG1253	flavin adenine dinucleotide binding
CRD75_RS01760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CRD75_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRD75_RS01780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CRD75_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CRD75_RS01790	COG1120	ATPase activity
CRD75_RS01800	COG2244	polysaccharide biosynthetic process
CRD75_RS01830	COG0470	DNA polymerase III
CRD75_RS01855	COG1393	Belongs to the ArsC family
CRD75_RS01860	COG0708	Exodeoxyribonuclease III
CRD75_RS01870	COG1304	FMN binding
CRD75_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
CRD75_RS01975	COG0673	inositol 2-dehydrogenase activity
CRD75_RS01990	COG0494	nUDIX hydrolase
CRD75_RS02000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CRD75_RS02090	COG1702	phosphate starvation-inducible protein PhoH
CRD75_RS02095	COG1573	uracil-dna glycosylase
CRD75_RS02105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CRD75_RS02205	COG0433	COG0433 Predicted ATPase
CRD75_RS02210	COG2814	Major facilitator Superfamily
CRD75_RS02225	COG0557	exoribonuclease II activity
CRD75_RS02255	COG0463	Glycosyl transferase, family 2
CRD75_RS02265	COG0778	Nitroreductase
CRD75_RS02270	COG0006	proline dipeptidase activity
CRD75_RS02275	COG1609	Transcriptional regulator
CRD75_RS02285	COG0438	transferase activity, transferring glycosyl groups
CRD75_RS02295	COG4555	ABC transporter
CRD75_RS02315	COG0183	Belongs to the thiolase family
CRD75_RS02330	COG0745	RESPONSE REGULATOR receiver
CRD75_RS02335	COG5002	protein histidine kinase activity
CRD75_RS02340	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CRD75_RS02350	COG1196	nuclear chromosome segregation
CRD75_RS02360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CRD75_RS02460	COG0561	phosphatase activity
CRD75_RS02465	COG0561	phosphatase activity
CRD75_RS02470	COG0552	protein localization to endoplasmic reticulum
CRD75_RS02475	COG0477	Major facilitator Superfamily
CRD75_RS02480	COG3711	transcriptional antiterminator
CRD75_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRD75_RS02485	COG1263	PTS System
CRD75_RS02485	COG2190	(PTS) system
CRD75_RS02495	COG3689	TIGRFAM TIGR03943 family protein
CRD75_RS02500	COG0701	Predicted permease
CRD75_RS02510	COG2183	response to ionizing radiation
CRD75_RS02555	COG0826	peptidase U32
CRD75_RS02560	COG4443	Transcriptional Coactivator p15 (PC4)
CRD75_RS02610	COG0386	Belongs to the glutathione peroxidase family
CRD75_RS02615	COG1164	Oligoendopeptidase f
CRD75_RS02625	COG0772	Belongs to the SEDS family
CRD75_RS02660	COG1078	dGTPase activity
CRD75_RS02675	COG1609	Transcriptional regulator
CRD75_RS02685	COG3716	PTS system mannose fructose sorbose family IID component
CRD75_RS02690	COG3715	PTS system
CRD75_RS02695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRD75_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
CRD75_RS02725	COG0800	Aldolase
CRD75_RS02730	COG0546	phosphoglycolate phosphatase activity
CRD75_RS02735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CRD75_RS02745	COG2884	Cell division ATP-binding protein ftsE
CRD75_RS02750	COG2177	Part of the ABC transporter FtsEX involved in
CRD75_RS02765	COG1199	ATP-dependent helicase activity
CRD75_RS02765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CRD75_RS02770	COG0436	Aminotransferase
CRD75_RS02805	COG2188	Transcriptional regulator
CRD75_RS02810	COG2222	sugar isomerase
CRD75_RS02820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CRD75_RS02825	COG0716	FMN binding
CRD75_RS02835	COG0038	chloride channel
CRD75_RS02930	COG1131	(ABC) transporter
CRD75_RS02955	COG4708	membrane
CRD75_RS02965	COG1597	lipid kinase activity
CRD75_RS03050	COG0577	efflux transmembrane transporter activity
CRD75_RS03060	COG2321	neutral zinc metallopeptidase
CRD75_RS03075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRD75_RS03085	COG1970	mechanosensitive ion channel activity
CRD75_RS03090	COG0358	DNA primase activity
CRD75_RS03095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CRD75_RS03100	COG2151	metal-sulfur cluster biosynthetic enzyme
CRD75_RS03145	COG1216	Glycosyl transferase, family 2
CRD75_RS03205	COG1368	sulfuric ester hydrolase activity
CRD75_RS03210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CRD75_RS03230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CRD75_RS03235	COG0285	dihydrofolate synthase activity
CRD75_RS03245	COG1104	cysteine desulfurase activity
CRD75_RS03270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CRD75_RS03280	COG0583	DNA-binding transcription factor activity
CRD75_RS03290	COG0564	pseudouridine synthase activity
CRD75_RS03325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CRD75_RS03330	COG1136	(ABC) transporter
CRD75_RS03335	COG0577	efflux transmembrane transporter activity
CRD75_RS03340	COG0584	glycerophosphoryl diester phosphodiesterase
CRD75_RS03350	COG1837	Belongs to the UPF0109 family
CRD75_RS03400	COG1349	DNA-binding transcription factor activity
CRD75_RS03405	COG1105	Belongs to the carbohydrate kinase PfkB family
CRD75_RS03410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRD75_RS03410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRD75_RS03410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CRD75_RS03415	COG1388	LysM domain
CRD75_RS03415	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRD75_RS03420	COG1388	LysM domain
CRD75_RS03420	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRD75_RS03440	COG0105	UTP biosynthetic process
CRD75_RS03460	COG0488	(ABC) transporter
CRD75_RS03470	COG0242	peptide deformylase activity
CRD75_RS03475	COG0737	Belongs to the 5'-nucleotidase family
CRD75_RS03480	COG2357	RelA SpoT domain protein
CRD75_RS03485	COG0745	RESPONSE REGULATOR receiver
CRD75_RS03520	COG3425	synthase
CRD75_RS03530	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CRD75_RS03575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CRD75_RS03590	COG0583	DNA-binding transcription factor activity
CRD75_RS03615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRD75_RS03620	COG0765	amino acid transport
CRD75_RS03640	COG0187	DNA topoisomerase II activity
CRD75_RS03650	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CRD75_RS03670	COG0539	negative regulation of cytoplasmic translation
CRD75_RS03715	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CRD75_RS03720	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
CRD75_RS03730	COG0300	oxidoreductase activity
CRD75_RS03735	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CRD75_RS03735	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CRD75_RS03750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CRD75_RS03755	COG2384	SAM-dependent methyltransferase
CRD75_RS03765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CRD75_RS03770	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CRD75_RS03780	COG1088	dTDP-glucose 4,6-dehydratase activity
CRD75_RS03785	COG1051	belongs to the nudix hydrolase family
CRD75_RS03790	COG0628	permease
CRD75_RS03795	COG0457	Tetratricopeptide repeat
CRD75_RS03800	COG1293	RNA-binding protein homologous to eukaryotic snRNP
CRD75_RS03820	COG1129	ABC transporter
CRD75_RS03840	COG0488	(ABC) transporter
CRD75_RS03845	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CRD75_RS03850	COG0022	dehydrogenase e1 component
CRD75_RS03850	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRD75_RS03855	COG0508	dehydrogenase complex catalyzes the overall conversion of
CRD75_RS03875	COG5492	domain, Protein
CRD75_RS03880	COG0095	Lipoate-protein ligase
CRD75_RS03885	COG3442	glutamine amidotransferase
CRD75_RS03890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CRD75_RS03895	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CRD75_RS03915	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CRD75_RS03925	COG0647	UMP catabolic process
CRD75_RS03940	COG1518	maintenance of DNA repeat elements
CRD75_RS03945	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CRD75_RS03955	COG5433	transposase activity
CRD75_RS03995	COG3715	PTS system
CRD75_RS04000	COG3716	PTS system mannose fructose sorbose family IID component
CRD75_RS04005	COG2972	Histidine kinase
CRD75_RS04010	COG2207	Transcriptional regulator
CRD75_RS04010	COG4753	response regulator
CRD75_RS04020	COG1012	belongs to the aldehyde dehydrogenase family
CRD75_RS04035	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRD75_RS04110	COG1131	(ABC) transporter
CRD75_RS04125	COG1396	sequence-specific DNA binding
CRD75_RS04155	COG0285	dihydrofolate synthase activity
CRD75_RS04175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CRD75_RS04190	COG1176	ABC-type spermidine putrescine transport system, permease component I
CRD75_RS04195	COG1177	transmembrane transport
CRD75_RS04205	COG4565	transcriptional regulatory protein
CRD75_RS04210	COG3290	protein histidine kinase activity
CRD75_RS04215	COG3493	citrate carrier protein
CRD75_RS04225	COG1063	alcohol dehydrogenase
CRD75_RS04230	COG3700	Belongs to the class B bacterial acid phosphatase family
CRD75_RS04235	COG0038	chloride channel
CRD75_RS04245	COG0628	permease
CRD75_RS04255	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CRD75_RS04270	COG1104	cysteine desulfurase activity
CRD75_RS04285	COG2357	RelA SpoT domain protein
CRD75_RS04295	COG0564	pseudouridine synthase activity
CRD75_RS04300	COG0280	phosphate acetyltransferase
CRD75_RS04305	COG4221	oxidoreductase activity
CRD75_RS04320	COG1174	glycine betaine transport
CRD75_RS04340	COG2233	PERMEase
CRD75_RS04365	COG2890	protein-(glutamine-N5) methyltransferase activity
CRD75_RS04395	COG1132	(ABC) transporter
CRD75_RS04400	COG1132	(ABC) transporter
CRD75_RS04420	COG3764	Sortase (surface protein transpeptidase)
CRD75_RS04425	COG0346	lactoylglutathione lyase activity
CRD75_RS04440	COG1597	lipid kinase activity
CRD75_RS04445	COG1272	protein, Hemolysin III
CRD75_RS04470	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CRD75_RS04520	COG0511	ligase activity, forming carbon-carbon bonds
CRD75_RS04525	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CRD75_RS04540	COG2851	Citrate transporter
CRD75_RS04550	COG0511	ligase activity, forming carbon-carbon bonds
CRD75_RS04555	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CRD75_RS04585	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CRD75_RS04605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CRD75_RS04615	COG2188	Transcriptional regulator
CRD75_RS04635	COG0488	(ABC) transporter
CRD75_RS04645	COG0352	thiamine-phosphate diphosphorylase activity
CRD75_RS04645	COG0351	phosphomethylpyrimidine kinase
CRD75_RS04650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CRD75_RS04655	COG1328	CTP reductase activity
CRD75_RS04655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CRD75_RS04660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CRD75_RS04690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CRD75_RS04710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CRD75_RS04715	COG4684	Psort location CytoplasmicMembrane, score
CRD75_RS04720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRD75_RS04725	COG1079	Belongs to the binding-protein-dependent transport system permease family
CRD75_RS04730	COG4603	Belongs to the binding-protein-dependent transport system permease family
CRD75_RS04735	COG3845	ABC transporter
CRD75_RS04740	COG1744	ABC transporter substrate-binding protein PnrA-like
CRD75_RS04745	COG0295	cytidine deaminase activity
CRD75_RS04750	COG2813	Specifically methylates the guanine in position
CRD75_RS04765	COG5002	protein histidine kinase activity
CRD75_RS04770	COG0745	RESPONSE REGULATOR receiver
CRD75_RS04785	COG0704	Plays a role in the regulation of phosphate uptake
CRD75_RS04800	COG0581	inorganic phosphate transmembrane transporter activity
CRD75_RS04805	COG0573	inorganic phosphate transmembrane transporter activity
CRD75_RS04815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRD75_RS04815	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CRD75_RS04820	COG0483	inositol monophosphate 1-phosphatase activity
CRD75_RS04835	COG0196	riboflavin kinase activity
CRD75_RS04865	COG4591	ABC-type transport system involved in lipoprotein release permease component
CRD75_RS04865	COG1136	(ABC) transporter
CRD75_RS04915	COG1115	amino acid carrier protein
CRD75_RS04920	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CRD75_RS04930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRD75_RS04935	COG1126	abc transporter atp-binding protein
CRD75_RS04940	COG0765	amino acid transport
CRD75_RS04945	COG2824	Alkylphosphonate utilization operon protein PhnA
CRD75_RS04960	COG0469	pyruvate kinase activity
CRD75_RS04975	COG1725	Transcriptional regulator
CRD75_RS04980	COG1131	(ABC) transporter
CRD75_RS05165	COG1598	PFAM Uncharacterised protein family UPF0150
CRD75_RS05350	COG0058	SHG alpha-glucan phosphorylase activity
CRD75_RS05355	COG1640	4-alpha-glucanotransferase
CRD75_RS05360	COG1609	Transcriptional regulator
CRD75_RS05365	COG2182	Extracellular solute-binding protein
CRD75_RS05370	COG1175	transmembrane transport
CRD75_RS05375	COG3833	ABC-type maltose transport systems, permease component
CRD75_RS05390	COG3833	ABC-type maltose transport systems, permease component
CRD75_RS05395	COG1175	transmembrane transport
CRD75_RS05405	COG0366	Alpha amylase catalytic
CRD75_RS05410	COG2182	Extracellular solute-binding protein
CRD75_RS05420	COG0657	acetylesterase activity
CRD75_RS05425	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CRD75_RS05435	COG1696	Membrane protein involved in D-alanine export
CRD75_RS05455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CRD75_RS05460	COG1126	abc transporter atp-binding protein
CRD75_RS05465	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRD75_RS05475	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRD75_RS05485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CRD75_RS05485	COG3711	transcriptional antiterminator
CRD75_RS05495	COG2723	6-phospho-beta-galactosidase activity
CRD75_RS05525	COG1187	pseudouridine synthase activity
CRD75_RS05535	COG2814	Major facilitator Superfamily
CRD75_RS05650	COG4109	DRTGG domain
CRD75_RS05655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CRD75_RS05680	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CRD75_RS05680	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CRD75_RS05690	COG5433	transposase activity
CRD75_RS05695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CRD75_RS05700	COG1956	GAF domain-containing protein
CRD75_RS05720	COG0513	Belongs to the DEAD box helicase family
CRD75_RS05725	COG0726	polysaccharide deacetylase
CRD75_RS05745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CRD75_RS05750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CRD75_RS05770	COG2801	Transposase and inactivated derivatives
CRD75_RS05785	COG1476	TRANSCRIPTIONal
CRD75_RS05800	COG4122	O-methyltransferase activity
CRD75_RS05805	COG2223	nitrite transmembrane transporter activity
CRD75_RS05820	COG1187	pseudouridine synthase activity
CRD75_RS05870	COG1555	photosystem II stabilization
CRD75_RS05870	COG1596	polysaccharide export
CRD75_RS05875	COG0204	Acyl-transferase
CRD75_RS05880	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CRD75_RS05895	COG0513	Belongs to the DEAD box helicase family
CRD75_RS05915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CRD75_RS05930	COG0768	penicillin binding
CRD75_RS05935	COG2116	formate transmembrane transporter activity
CRD75_RS05945	COG1827	regulation of RNA biosynthetic process
CRD75_RS05960	COG2217	Heavy metal translocating P-type atpase
CRD75_RS05975	COG2755	lipolytic protein G-D-S-L family
CRD75_RS05990	COG0497	DNA recombination
CRD75_RS05995	COG1438	arginine binding
CRD75_RS06000	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CRD75_RS06025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CRD75_RS06030	COG0415	Belongs to the DNA photolyase family
CRD75_RS06040	COG0765	amino acid transport
CRD75_RS06045	COG4703	Protein of unknown function (DUF1797)
CRD75_RS06050	COG0542	response to heat
CRD75_RS06055	COG0494	nUDIX hydrolase
CRD75_RS06070	COG3599	regulation of cell shape
CRD75_RS06075	COG2302	S4 RNA-binding domain
CRD75_RS06090	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CRD75_RS06125	COG1217	gtp-binding protein TYPA
CRD75_RS06130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CRD75_RS06135	COG1940	carbohydrate kinase activity
CRD75_RS06145	COG0783	Belongs to the Dps family
CRD75_RS06160	COG4470	Protein conserved in bacteria
CRD75_RS06165	COG1609	Transcriptional regulator
CRD75_RS06170	COG3480	Lon protease (S16) C-terminal proteolytic domain
CRD75_RS06180	COG0742	ribosomal rna small subunit methyltransferase
CRD75_RS06190	COG0549	Belongs to the carbamate kinase family
CRD75_RS06195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CRD75_RS06200	COG1288	antiporter activity
CRD75_RS06215	COG2235	arginine
CRD75_RS06240	COG2972	Histidine kinase
CRD75_RS06255	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CRD75_RS06260	COG0785	Cytochrome C biogenesis protein
CRD75_RS06265	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CRD75_RS06270	COG1518	maintenance of DNA repeat elements
CRD75_RS06335	COG5433	transposase activity
CRD75_RS06390	COG0433	COG0433 Predicted ATPase
CRD75_RS06440	COG1674	ftsk spoiiie
CRD75_RS06480	COG1396	sequence-specific DNA binding
CRD75_RS06520	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CRD75_RS06520	COG1605	Chorismate mutase
CRD75_RS06540	COG2226	methyltransferase
CRD75_RS06550	COG3250	beta-galactosidase activity
CRD75_RS06555	COG2207	Transcriptional regulator
CRD75_RS06555	COG4753	response regulator
CRD75_RS06560	COG2972	Histidine kinase
CRD75_RS06570	COG1653	transport
CRD75_RS06575	COG0395	ABC-type sugar transport system, permease component
CRD75_RS06580	COG1175	transmembrane transport
CRD75_RS06590	COG2723	6-phospho-beta-galactosidase activity
CRD75_RS06595	COG3525	Glycosyl hydrolase, family 20, catalytic domain
CRD75_RS06600	COG1609	Transcriptional regulator
CRD75_RS06610	COG0383	alpha-mannosidase activity
CRD75_RS06715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CRD75_RS06720	COG1739	Uncharacterized protein family UPF0029
CRD75_RS06730	COG1098	S1 RNA binding domain
CRD75_RS06740	COG2197	response regulator
CRD75_RS06745	COG4585	Histidine kinase
CRD75_RS06755	COG2815	serine threonine protein kinase
CRD75_RS06755	COG0515	serine threonine protein kinase
CRD75_RS06765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CRD75_RS06765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CRD75_RS06775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CRD75_RS06795	COG0583	DNA-binding transcription factor activity
CRD75_RS06800	COG0183	Belongs to the thiolase family
CRD75_RS06805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CRD75_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
CRD75_RS06820	COG2610	gluconate transmembrane transporter activity
CRD75_RS06835	COG0116	Belongs to the methyltransferase superfamily
CRD75_RS06860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRD75_RS06865	COG3579	cysteine-type endopeptidase activity
CRD75_RS06875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CRD75_RS06880	COG1113	amino acid transport
CRD75_RS06885	COG0492	ferredoxin-NADP+ reductase activity
CRD75_RS06895	COG1126	abc transporter atp-binding protein
CRD75_RS06905	COG0513	Belongs to the DEAD box helicase family
CRD75_RS06915	COG0768	penicillin binding
CRD75_RS06950	COG1131	(ABC) transporter
CRD75_RS06975	COG0446	pyridine nucleotide-disulphide oxidoreductase
CRD75_RS06980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRD75_RS07020	COG1755	Isoprenylcysteine carboxyl methyltransferase
CRD75_RS07025	COG0656	L-ascorbic acid biosynthetic process
CRD75_RS07035	COG1283	sodium-dependent phosphate transmembrane transporter activity
CRD75_RS07055	COG0561	phosphatase activity
CRD75_RS07060	COG2860	membrane
CRD75_RS07115	COG2217	Heavy metal translocating P-type atpase
CRD75_RS07145	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CRD75_RS07150	COG0195	Participates in both transcription termination and antitermination
CRD75_RS07175	COG4473	ABC transporter
CRD75_RS07180	COG1131	(ABC) transporter
CRD75_RS07185	COG0537	adenosine 5'-monophosphoramidase activity
CRD75_RS07195	COG1316	TRANSCRIPTIONal
CRD75_RS07205	COG0802	atpase or kinase
CRD75_RS07210	COG2252	PERMEase
CRD75_RS07215	COG0561	phosphatase activity
CRD75_RS07225	COG3715	PTS system
CRD75_RS07230	COG3716	PTS system mannose fructose sorbose family IID component
CRD75_RS07255	COG0439	Biotin carboxylase
CRD75_RS07270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CRD75_RS07275	COG1028	Short-chain dehydrogenase reductase Sdr
CRD75_RS07280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CRD75_RS07305	COG1024	Enoyl-CoA hydratase
CRD75_RS07340	COG0588	phosphoglycerate mutase activity
CRD75_RS07345	COG2261	transglycosylase associated protein
CRD75_RS07380	COG1335	isochorismatase
CRD75_RS07390	COG0436	Aminotransferase
CRD75_RS07400	COG0561	phosphatase activity
CRD75_RS07405	COG0252	asparaginase activity
CRD75_RS07420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CRD75_RS07430	COG1129	ABC transporter
CRD75_RS07445	COG1132	(ABC) transporter
CRD75_RS07450	COG1132	(ABC) transporter
CRD75_RS07455	COG1120	ATPase activity
CRD75_RS07480	COG1388	LysM domain
CRD75_RS07480	COG3942	CHAP domain
CRD75_RS07500	COG1482	cell wall glycoprotein biosynthetic process
CRD75_RS07505	COG1940	carbohydrate kinase activity
CRD75_RS07515	COG1263	PTS System
CRD75_RS07515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRD75_RS07515	COG2190	(PTS) system
CRD75_RS07520	COG1621	beta-fructofuranosidase activity
CRD75_RS07525	COG1609	Transcriptional regulator
CRD75_RS07545	COG2131	deaminase
CRD75_RS07550	COG0006	proline dipeptidase activity
CRD75_RS07590	COG1194	a g-specific adenine glycosylase
CRD75_RS07600	COG3118	belongs to the thioredoxin family
CRD75_RS07630	COG0681	Belongs to the peptidase S26 family
CRD75_RS07635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CRD75_RS07650	COG1882	Formate acetyltransferase
CRD75_RS07655	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CRD75_RS07670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CRD75_RS07680	COG2814	Major facilitator Superfamily
CRD75_RS07685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CRD75_RS07710	COG0789	Transcriptional regulator
CRD75_RS07745	COG2081	HI0933 family
CRD75_RS07755	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CRD75_RS07760	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CRD75_RS07780	COG0456	acetyltransferase
CRD75_RS07785	COG1214	PFAM Peptidase M22, glycoprotease
CRD75_RS07800	COG0174	glutamine synthetase
CRD75_RS07805	COG0789	Transcriptional regulator
CRD75_RS07820	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
CRD75_RS07875	COG0668	transmembrane transport
CRD75_RS07885	COG4720	Psort location CytoplasmicMembrane, score
CRD75_RS07890	COG0351	phosphomethylpyrimidine kinase
CRD75_RS07935	COG1929	Belongs to the glycerate kinase type-1 family
CRD75_RS07940	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CRD75_RS07970	COG0577	efflux transmembrane transporter activity
CRD75_RS07975	COG1136	(ABC) transporter
CRD75_RS08000	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRD75_RS08000	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRD75_RS08005	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRD75_RS08055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CRD75_RS08060	COG1476	TRANSCRIPTIONal
CRD75_RS08080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CRD75_RS08090	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CRD75_RS08110	COG1045	serine acetyltransferase
CRD75_RS08125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CRD75_RS08140	COG3711	transcriptional antiterminator
CRD75_RS08165	COG0431	NADPH-dependent FMN reductase
CRD75_RS08170	COG1846	Transcriptional regulator
CRD75_RS08190	COG4589	Belongs to the CDS family
CRD75_RS08200	COG1862	Preprotein translocase
CRD75_RS08210	COG1523	belongs to the glycosyl hydrolase 13 family
CRD75_RS08225	COG3842	ATPase activity
CRD75_RS08265	COG1263	PTS System
CRD75_RS08265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRD75_RS08265	COG2190	(PTS) system
CRD75_RS08270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CRD75_RS08285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CRD75_RS08290	COG0512	Glutamine amidotransferase of anthranilate synthase
CRD75_RS08295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CRD75_RS08335	COG0601	transmembrane transport
CRD75_RS08345	COG1122	ATPase activity
CRD75_RS08365	COG0803	Belongs to the bacterial solute-binding protein 9 family
CRD75_RS08375	COG5433	transposase activity
CRD75_RS08405	COG3711	transcriptional antiterminator
CRD75_RS08420	COG3942	CHAP domain
CRD75_RS08420	COG1705	Flagellar rod assembly protein muramidase FlgJ
CRD75_RS08425	COG2205	protein histidine kinase activity
CRD75_RS08430	COG0745	RESPONSE REGULATOR receiver
CRD75_RS08435	COG0577	efflux transmembrane transporter activity
CRD75_RS08440	COG1136	(ABC) transporter
CRD75_RS08515	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CRD75_RS08530	COG1882	Formate acetyltransferase
CRD75_RS08535	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRD75_RS08540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CRD75_RS08545	COG1447	Phosphotransferase system cellobiose-specific component IIA
CRD75_RS08550	COG2390	Transcriptional regulator
CRD75_RS08555	COG1349	DNA-binding transcription factor activity
CRD75_RS08560	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CRD75_RS08580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CRD75_RS08595	COG0564	pseudouridine synthase activity
CRD75_RS08630	COG0542	response to heat
CRD75_RS08635	COG4463	regulation of RNA biosynthetic process
CRD75_RS08650	COG0450	alkyl hydroperoxide reductase
CRD75_RS08665	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CRD75_RS08675	COG3404	Formiminotransferase-cyclodeaminase
CRD75_RS08690	COG0531	amino acid
CRD75_RS08720	COG3590	peptidase
CRD75_RS08725	COG0366	Alpha amylase catalytic
CRD75_RS08730	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CRD75_RS08730	COG1263	PTS System
CRD75_RS08735	COG2188	Transcriptional regulator
CRD75_RS08750	COG2514	catechol 2,3-dioxygenase activity
CRD75_RS08760	COG0602	queuosine metabolic process
CRD75_RS08780	COG1328	CTP reductase activity
CRD75_RS08805	COG1393	Belongs to the ArsC family
CRD75_RS08820	COG0519	Catalyzes the synthesis of GMP from XMP
CRD75_RS08840	COG0582	viral genome integration into host DNA
CRD75_RS08985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRD75_RS08990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRD75_RS08995	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRD75_RS09080	COG1511	domain protein
CRD75_RS09200	COG0582	viral genome integration into host DNA
CRD75_RS09215	COG0305	Participates in initiation and elongation during chromosome replication
CRD75_RS09245	COG1760	l-serine dehydratase
CRD75_RS09250	COG1760	l-serine dehydratase
CRD75_RS09255	COG0741	lytic transglycosylase activity
CRD75_RS09260	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CRD75_RS09275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CRD75_RS09285	COG0612	Peptidase, M16
CRD75_RS09310	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CRD75_RS09330	COG0517	IMP dehydrogenase activity
CRD75_RS09330	COG0516	GMP reductase activity
CRD75_RS09340	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CRD75_RS09345	COG0488	(ABC) transporter
CRD75_RS09380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CRD75_RS09385	COG1475	DNA binding