locus-tag class description SPy_0002 PF08299 Bacterial dnaA protein helix-turn-helix SPy_0002 PF00308 Bacterial dnaA protein SPy_0003 PF00712 DNA polymerase III beta subunit, N-terminal domain SPy_0003 PF02768 DNA polymerase III beta subunit, C-terminal domain SPy_0003 PF02767 DNA polymerase III beta subunit, central domain SPy_0006 PF06071 Protein of unknown function (DUF933) SPy_0006 PF01926 50S ribosome-binding GTPase SPy_0007 PF01195 Peptidyl-tRNA hydrolase SPy_0008 PF00271 Helicase conserved C-terminal domain SPy_0008 PF00270 DEAD/DEAH box helicase SPy_0008 PF02559 CarD-like/TRCF domain SPy_0008 PF03461 TRCF domain SPy_0008 PF17757 UvrB interaction domain SPy_0009 PF01479 S4 domain SPy_0013 PF01171 PP-loop family SPy_0015 PF01434 Peptidase family M41 SPy_0015 PF00004 ATPase family associated with various cellular activities (AAA) SPy_0015 PF06480 FtsH Extracellular SPy_0015 PF17862 AAA+ lid domain SPy_0016 PF13520 Amino acid permease SPy_0019 PF01476 LysM domain SPy_0019 PF05257 CHAP domain SPy_0020 PF14572 Phosphoribosyl synthetase-associated domain SPy_0020 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPy_0021 PF02565 Recombination protein O C terminal SPy_0021 PF11967 Recombination protein O N terminal SPy_0022 PF02504 Fatty acid synthesis protein SPy_0023 PF00550 Phosphopantetheine attachment site SPy_0024 PF01259 SAICAR synthetase SPy_0025 PF02769 AIR synthase related protein, C-terminal domain SPy_0025 PF18072 Formylglycinamide ribonucleotide amidotransferase linker domain SPy_0025 PF00586 AIR synthase related protein, N-terminal domain SPy_0026 PF13537 Glutamine amidotransferase domain SPy_0026 PF00156 Phosphoribosyl transferase domain SPy_0027 PF02769 AIR synthase related protein, C-terminal domain SPy_0027 PF00586 AIR synthase related protein, N-terminal domain SPy_0028 PF00551 Formyl transferase SPy_0032 PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain SPy_0032 PF02844 Phosphoribosylglycinamide synthetase, N domain SPy_0032 PF02843 Phosphoribosylglycinamide synthetase, C domain SPy_0033 PF00731 AIR carboxylase SPy_0034 PF17769 Phosphoribosylaminoimidazole carboxylase C-terminal domain SPy_0034 PF02222 ATP-grasp domain SPy_0036 PF10397 Adenylosuccinate lyase C-terminus SPy_0036 PF00206 Lyase SPy_0038 PF17864 RuvB AAA lid domain SPy_0038 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPy_0038 PF05491 RuvB C-terminal winged helix domain SPy_0039 PF01451 Low molecular weight phosphotyrosine protein phosphatase SPy_0041 PF01757 Acyltransferase family SPy_0044 PF00107 Zinc-binding dehydrogenase SPy_0044 PF08240 Alcohol dehydrogenase GroES-like domain SPy_0045 PF01554 MatE SPy_0047 PF00338 Ribosomal protein S10p/S20e SPy_0049 PF00297 Ribosomal protein L3 SPy_0050 PF00573 Ribosomal protein L4/L1 family SPy_0051 PF00276 Ribosomal protein L23 SPy_0052 PF03947 Ribosomal Proteins L2, C-terminal domain SPy_0052 PF00181 Ribosomal Proteins L2, RNA binding domain SPy_0053 PF00203 Ribosomal protein S19 SPy_0055 PF00237 Ribosomal protein L22p/L17e SPy_0056 PF00189 Ribosomal protein S3, C-terminal domain SPy_0056 PF07650 KH domain SPy_0057 PF00252 Ribosomal protein L16p/L10e SPy_0059 PF00831 Ribosomal L29 protein SPy_0060 PF00366 Ribosomal protein S17 SPy_0061 PF00238 Ribosomal protein L14p/L23e SPy_0062 PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 SPy_0062 PF00467 KOW motif SPy_0063 PF00673 ribosomal L5P family C-terminus SPy_0063 PF00281 Ribosomal protein L5 SPy_0064 PF00253 Ribosomal protein S14p/S29e SPy_0065 PF00410 Ribosomal protein S8 SPy_0066 PF00347 Ribosomal protein L6 SPy_0067 PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast SPy_0069 PF00333 Ribosomal protein S5, N-terminal domain SPy_0069 PF03719 Ribosomal protein S5, C-terminal domain SPy_0071 PF00327 Ribosomal protein L30p/L7e SPy_0072 PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SPy_0073 PF00344 SecY translocase SPy_0075 PF01176 Translation initiation factor 1A / IF-1 SPy_0076 PF00444 Ribosomal protein L36 SPy_0077 PF00416 Ribosomal protein S13/S18 SPy_0078 PF00411 Ribosomal protein S11 SPy_0080 PF01000 RNA polymerase Rpb3/RpoA insert domain SPy_0080 PF03118 Bacterial RNA polymerase, alpha chain C terminal domain SPy_0080 PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain SPy_0092 PF01047 MarR family SPy_0093 PF00005 ABC transporter SPy_0094 PF00950 ABC 3 transport family SPy_0096 PF00579 tRNA synthetases class I (W and Y) SPy_0096 PF01479 S4 domain SPy_0097 PF00912 Transglycosylase SPy_0097 PF00905 Penicillin binding protein transpeptidase domain SPy_0098 PF04561 RNA polymerase Rpb2, domain 2 SPy_0098 PF04565 RNA polymerase Rpb2, domain 3 SPy_0098 PF10385 RNA polymerase beta subunit external 1 domain SPy_0098 PF00562 RNA polymerase Rpb2, domain 6 SPy_0098 PF04563 RNA polymerase beta subunit SPy_0098 PF04560 RNA polymerase Rpb2, domain 7 SPy_0099 PF04998 RNA polymerase Rpb1, domain 5 SPy_0099 PF05000 RNA polymerase Rpb1, domain 4 SPy_0099 PF04983 RNA polymerase Rpb1, domain 3 SPy_0099 PF00623 RNA polymerase Rpb1, domain 2 SPy_0099 PF04997 RNA polymerase Rpb1, domain 1 SPy_0101 PF00437 Type II/IV secretion system protein SPy_0102 PF00482 Type II secretion system (T2SS), protein F SPy_0103 PF07963 Prokaryotic N-terminal methylation motif SPy_0109 PF00871 Acetokinase family SPy_0112 PF14748 Pyrroline-5-carboxylate reductase dimerisation SPy_0112 PF03807 NADP oxidoreductase coenzyme F420-dependent SPy_0115 PF05343 M42 glutamyl aminopeptidase SPy_0121 PF01712 Deoxynucleoside kinase SPy_0122 PF01207 Dihydrouridine synthase (Dus) SPy_0123 PF01430 Hsp33 protein SPy_0128 PF12892 Spy0128-like isopeptide containing domain SPy_0129 PF04203 Sortase domain SPy_0131 PF13005 zinc-finger binding domain of transposase IS66 SPy_0131 PF13007 Transposase C of IS166 homeodomain SPy_0131 PF13817 IS66 C-terminal element SPy_0131 PF03050 Transposase IS66 family SPy_0137 PF02667 Short chain fatty acid transporter SPy_0140 PF00108 Thiolase, N-terminal domain SPy_0140 PF02803 Thiolase, C-terminal domain SPy_0141 PF01144 Coenzyme A transferase SPy_0142 PF01144 Coenzyme A transferase SPy_0145 PF01042 Endoribonuclease L-PSP SPy_0148 PF01496 V-type ATPase 116kDa subunit family SPy_0149 PF00137 ATP synthase subunit C SPy_0151 PF01992 ATP synthase (C/AC39) subunit SPy_0154 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPy_0154 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPy_0154 PF16886 ATPsynthase alpha/beta subunit N-term extension SPy_0155 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPy_0155 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPy_0157 PF01813 ATP synthase subunit D SPy_0160 PF00709 Adenylosuccinate synthetase SPy_0163 PF02608 ABC transporter substrate-binding protein PnrA-like SPy_0164 PF00467 KOW motif SPy_0164 PF02357 Transcription termination factor nusG SPy_0167 PF17440 Thiol-activated cytolysin beta sandwich domain SPy_0167 PF01289 Thiol-activated cytolysin SPy_0172 PF01053 Cys/Met metabolism PLP-dependent enzyme SPy_0173 PF13603 Leucyl-tRNA synthetase, Domain 2 SPy_0173 PF00133 tRNA synthetases class I (I, L, M and V) SPy_0173 PF08264 Anticodon-binding domain of tRNA SPy_0173 PF09334 tRNA synthetases class I (M) SPy_0174 PF03611 PTS system sugar-specific permease component SPy_0175 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_0176 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPy_0177 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPy_0178 PF01261 Xylose isomerase-like TIM barrel SPy_0179 PF00596 Class II Aldolase and Adducin N-terminal domain SPy_0183 PF00571 CBS domain SPy_0183 PF00005 ABC transporter SPy_0184 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0185 PF01367 5'-3' exonuclease, C-terminal SAM fold SPy_0185 PF00476 DNA polymerase family A SPy_0185 PF02739 5'-3' exonuclease, N-terminal resolvase-like domain SPy_0187 PF01475 Ferric uptake regulator family SPy_0189 PF11922 Domain of unknown function (DUF3440) SPy_0189 PF01507 Phosphoadenosine phosphosulfate reductase family SPy_0190 PF02195 ParB-like nuclease domain SPy_0197 PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain SPy_0197 PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain SPy_0198 PF13276 HTH-like domain SPy_0198 PF00665 Integrase core domain SPy_0198 PF13333 Integrase core domain SPy_0203 PF01702 Queuine tRNA-ribosyltransferase SPy_0207 PF02632 BioY family SPy_0208 PF12706 Beta-lactamase superfamily domain SPy_0212 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_0212 PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain SPy_0215 PF00342 Phosphoglucose isomerase SPy_0223 PF01694 Rhomboid family SPy_0224 PF00483 Nucleotidyl transferase SPy_0226 PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus SPy_0226 PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus SPy_0229 PF00664 ABC transporter transmembrane region SPy_0229 PF00005 ABC transporter SPy_0230 PF00664 ABC transporter transmembrane region SPy_0230 PF00005 ABC transporter SPy_0233 PF02677 Epoxyqueuosine reductase QueH SPy_0235 PF00692 dUTPase SPy_0236 PF18073 Rubredoxin metal binding domain SPy_0237 PF00484 Carbonic anhydrase SPy_0238 PF01987 Mitochondrial biogenesis AIM24 SPy_0239 PF00749 tRNA synthetases class I (E and Q), catalytic domain SPy_0242 PF00989 PAS fold SPy_0242 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain SPy_0242 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0242 PF17203 Single cache domain 3 SPy_0246 PF00825 Ribonuclease P SPy_0247 PF02096 60Kd inner membrane protein SPy_0248 PF14804 Jag N-terminus SPy_0248 PF01424 R3H domain SPy_0250 PF00468 Ribosomal protein L34 SPy_0251 PF04131 Putative N-acetylmannosamine-6-phosphate epimerase SPy_0254 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0255 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0257 PF00701 Dihydrodipicolinate synthetase family SPy_0258 PF00480 ROK family SPy_0260 PF01026 TatD related DNase SPy_0261 PF13331 Domain of unknown function (DUF4093) SPy_0262 PF00398 Ribosomal RNA adenine dimethylase SPy_0263 PF03193 RsgA GTPase SPy_0263 PF16745 RsgA N-terminal domain SPy_0264 PF00834 Ribulose-phosphate 3 epimerase family SPy_0265 PF04263 Thiamin pyrophosphokinase, catalytic domain SPy_0265 PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain SPy_0266 PF02646 RmuC family SPy_0267 PF01966 HD domain SPy_0268 PF00156 Phosphoribosyl transferase domain SPy_0268 PF09182 Bacterial purine repressor, N-terminal SPy_0271 PF00164 Ribosomal protein S12/S23 SPy_0272 PF00177 Ribosomal protein S7p/S5e SPy_0273 PF03764 Elongation factor G, domain IV SPy_0273 PF03144 Elongation factor Tu domain 2 SPy_0273 PF00679 Elongation factor G C-terminus SPy_0273 PF14492 Elongation Factor G, domain II SPy_0273 PF00009 Elongation factor Tu GTP binding domain SPy_0274 PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain SPy_0274 PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain SPy_0276 PF00005 ABC transporter SPy_0277 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0280 PF02673 Bacitracin resistance protein BacA SPy_0281 PF05389 Negative regulator of genetic competence (MecA) SPy_0282 PF00953 Glycosyl transferase family 4 SPy_0285 PF00005 ABC transporter SPy_0287 PF01458 Uncharacterized protein family (UPF0051) SPy_0288 PF00266 Aminotransferase class-V SPy_0289 PF01592 NifU-like N terminal domain SPy_0290 PF01458 Uncharacterized protein family (UPF0051) SPy_0292 PF00768 D-alanyl-D-alanine carboxypeptidase SPy_0292 PF07943 Penicillin-binding protein 5, C-terminal domain SPy_0294 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0295 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0295 PF12911 N-terminal TM domain of oligopeptide transport permease C SPy_0296 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPy_0296 PF00005 ABC transporter SPy_0297 PF08352 Oligopeptide/dipeptide transporter, C-terminal region SPy_0297 PF00005 ABC transporter SPy_0303 PF13808 DDE_Tnp_1-associated SPy_0303 PF01609 Transposase DDE domain SPy_0306 PF01926 50S ribosome-binding GTPase SPy_0307 PF01985 CRS1 / YhbY (CRM) domain SPy_0308 PF01467 Cytidylyltransferase-like SPy_0309 PF01966 HD domain SPy_0312 PF13649 Methyltransferase domain SPy_0314 PF05636 HIGH Nucleotidyl Transferase SPy_0316 PF01709 Transcriptional regulator SPy_0317 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPy_0319 PF03180 NLPA lipoprotein SPy_0320 PF09383 NIL domain SPy_0320 PF00005 ABC transporter SPy_0321 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0323 PF05525 Branched-chain amino acid transport protein SPy_0324 PF00375 Sodium:dicarboxylate symporter family SPy_0326 PF02080 TrkA-C domain SPy_0326 PF02254 TrkA-N domain SPy_0327 PF02386 Cation transport protein SPy_0329 PF02527 rRNA small subunit methyltransferase G SPy_0330 PF04011 LemA family SPy_0331 PF01435 Peptidase family M48 SPy_0336 PF00512 His Kinase A (phospho-acceptor) domain SPy_0336 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0336 PF18719 ArlS sensor domain SPy_0338 PF03477 ATP cone domain SPy_0340 PF07319 Primosomal protein DnaI N-terminus SPy_0340 PF01695 IstB-like ATP binding protein SPy_0341 PF01926 50S ribosome-binding GTPase SPy_0341 PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal SPy_0342 PF00176 SNF2 family N-terminal domain SPy_0342 PF00271 Helicase conserved C-terminal domain SPy_0342 PF12419 SNF2 Helicase protein SPy_0345 PF08245 Mur ligase middle domain SPy_0345 PF01225 Mur ligase family, catalytic domain SPy_0345 PF02875 Mur ligase family, glutamate ligase domain SPy_0348 PF02618 YceG-like family SPy_0349 PF01272 Transcription elongation factor, GreA/GreB, C-term SPy_0349 PF03449 Transcription elongation factor, N-terminal SPy_0351 PF02096 60Kd inner membrane protein SPy_0352 PF00708 Acylphosphatase SPy_0356 PF00588 SpoU rRNA Methylase family SPy_0356 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPy_0358 PF01027 Inhibitor of apoptosis-promoting Bax1 SPy_0359 PF03672 Uncharacterised protein family (UPF0154) SPy_0361 PF01177 Asp/Glu/Hydantoin racemase SPy_0362 PF01725 Ham1 family SPy_0365 PF00589 Phage integrase family SPy_0366 PF02616 Segregation and condensation protein ScpA SPy_0367 PF04079 Segregation and condensation complex subunit ScpB SPy_0369 PF00849 RNA pseudouridylate synthase SPy_0369 PF01479 S4 domain SPy_0370 PF01809 Putative membrane protein insertion efficiency factor SPy_0371 PF00588 SpoU rRNA Methylase family SPy_0373 PF12822 ECF transporter, substrate-specific component SPy_0374 PF01569 PAP2 superfamily SPy_0376 PF16199 Radical_SAM C-terminal domain SPy_0376 PF04055 Radical SAM superfamily SPy_0377 PF06962 Putative rRNA methylase SPy_0378 PF01595 Cyclin M transmembrane N-terminal domain SPy_0378 PF03471 Transporter associated domain SPy_0378 PF00571 CBS domain SPy_0379 PF04055 Radical SAM superfamily SPy_0380 PF02833 DHHA2 domain SPy_0380 PF01368 DHH family SPy_0383 PF01032 FecCD transport family SPy_0384 PF01032 FecCD transport family SPy_0385 PF01497 Periplasmic binding protein SPy_0386 PF00005 ABC transporter SPy_0388 PF02875 Mur ligase family, glutamate ligase domain SPy_0388 PF08245 Mur ligase middle domain SPy_0390 PF14667 Polysaccharide biosynthesis C-terminal domain SPy_0390 PF01943 Polysaccharide biosynthesis protein SPy_0395 PF00574 Clp protease SPy_0397 PF09902 Uncharacterized protein conserved in bacteria (DUF2129) SPy_0399 PF02223 Thymidylate kinase SPy_0400 PF09115 DNA polymerase III, delta subunit, C terminal SPy_0405 PF06156 Initiation control protein YabA SPy_0406 PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases SPy_0408 PF03932 CutC family SPy_0410 PF03960 ArsC family SPy_0412 PF03372 Endonuclease/Exonuclease/phosphatase family SPy_0414 PF01070 FMN-dependent dehydrogenase SPy_0416 PF06280 Fn3-like domain SPy_0416 PF00082 Subtilase family SPy_0416 PF02225 PA domain SPy_0416 PF00746 LPXTG cell wall anchor motif SPy_0422 PF01588 Putative tRNA binding domain SPy_0422 PF09334 tRNA synthetases class I (M) SPy_0425 PF00268 Ribonucleotide reductase, small chain SPy_0426 PF07972 NrdI Flavodoxin like SPy_0427 PF02867 Ribonucleotide reductase, barrel domain SPy_0427 PF00317 Ribonucleotide reductase, all-alpha domain SPy_0427 PF08343 Ribonucleotide reductase N-terminal SPy_0428 PF03496 ADP-ribosyltransferase exoenzyme SPy_0436 PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain SPy_0436 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_0441 PF02894 Oxidoreductase family, C-terminal alpha/beta domain SPy_0441 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPy_0442 PF07690 Major Facilitator Superfamily SPy_0443 PF12804 MobA-like NTP transferase domain SPy_0443 PF00132 Bacterial transferase hexapeptide (six repeats) SPy_0444 PF00293 NUDIX domain SPy_0447 PF01048 Phosphorylase superfamily SPy_0453 PF01297 Zinc-uptake complex component A periplasmic SPy_0454 PF00005 ABC transporter SPy_0456 PF00950 ABC 3 transport family SPy_0457 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPy_0458 PF09397 Ftsk gamma domain SPy_0458 PF17854 FtsK alpha domain SPy_0458 PF01580 FtsK/SpoIIIE family SPy_0460 PF03946 Ribosomal protein L11, N-terminal domain SPy_0460 PF00298 Ribosomal protein L11, RNA binding domain SPy_0461 PF00687 Ribosomal protein L1p/L10e family SPy_0462 PF00696 Amino acid kinase family SPy_0463 PF01765 Ribosome recycling factor SPy_0466 PF01625 Peptide methionine sulfoxide reductase SPy_0467 PF06855 YozE SAM-like fold SPy_0470 PF06100 MCRA family SPy_0471 PF02562 PhoH-like protein SPy_0472 PF03167 Uracil DNA glycosylase superfamily SPy_0473 PF02130 Uncharacterized protein family UPF0054 SPy_0475 PF01219 Prokaryotic diacylglycerol kinase SPy_0476 PF07650 KH domain SPy_0476 PF01926 50S ribosome-binding GTPase SPy_0477 PF13344 Haloacid dehalogenase-like hydrolase SPy_0477 PF00293 NUDIX domain SPy_0497 PF06827 Zinc finger found in FPG and IleRS SPy_0497 PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain SPy_0497 PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain SPy_0498 PF01121 Dephospho-CoA kinase SPy_0500 PF05872 Bacterial protein of unknown function (DUF853) SPy_0501 PF07690 Major Facilitator Superfamily SPy_0501 PF00083 Sugar (and other) transporter SPy_0503 PF17876 Cold shock domain SPy_0503 PF00575 S1 RNA binding domain SPy_0503 PF08206 Ribonuclease B OB domain SPy_0503 PF00773 RNB domain SPy_0504 PF01668 SmpB protein SPy_0506 PF01470 Pyroglutamyl peptidase SPy_0510 PF00535 Glycosyl transferase family 2 SPy_0511 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPy_0512 PF00881 Nitroreductase family SPy_0513 PF00557 Metallopeptidase family M24 SPy_0513 PF01321 Creatinase/Prolidase N-terminal domain SPy_0514 PF00356 Bacterial regulatory proteins, lacI family SPy_0515 PF13439 Glycosyltransferase Family 4 SPy_0515 PF00534 Glycosyl transferases group 1 SPy_0516 PF00534 Glycosyl transferases group 1 SPy_0516 PF13439 Glycosyltransferase Family 4 SPy_0517 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPy_0517 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPy_0517 PF03129 Anticodon binding domain SPy_0517 PF02824 TGS domain SPy_0518 PF00005 ABC transporter SPy_0524 PF00108 Thiolase, N-terminal domain SPy_0524 PF02803 Thiolase, C-terminal domain SPy_0528 PF00072 Response regulator receiver domain SPy_0528 PF00486 Transcriptional regulatory protein, C terminal SPy_0529 PF13426 PAS domain SPy_0529 PF00512 His Kinase A (phospho-acceptor) domain SPy_0529 PF00672 HAMP domain SPy_0529 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0530 PF00753 Metallo-beta-lactamase superfamily SPy_0531 PF14622 Ribonuclease-III-like SPy_0531 PF00035 Double-stranded RNA binding motif SPy_0532 PF02463 RecF/RecN/SMC N terminal domain SPy_0532 PF06470 SMC proteins Flexible Hinge Domain SPy_0534 PF18317 Shikimate 5'-dehydrogenase C-terminal domain SPy_0534 PF08501 Shikimate dehydrogenase substrate binding domain SPy_0538 PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) SPy_0542 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPy_0542 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPy_0542 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPy_0555 PF04860 Phage portal protein SPy_0559 PF01336 OB-fold nucleic acid binding domain SPy_0559 PF00152 tRNA synthetases class II (D, K and N) SPy_0560 PF00206 Lyase SPy_0560 PF02655 ATP-grasp domain SPy_0569 PF02881 SRP54-type protein, helical bundle domain SPy_0569 PF00448 SRP54-type protein, GTPase domain SPy_0570 PF07690 Major Facilitator Superfamily SPy_0571 PF03123 CAT RNA binding domain SPy_0571 PF00874 PRD domain SPy_0572 PF00367 phosphotransferase system, EIIB SPy_0572 PF02378 Phosphotransferase system, EIIC SPy_0572 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPy_0574 PF00232 Glycosyl hydrolase family 1 SPy_0575 PF09323 Domain of unknown function (DUF1980) SPy_0576 PF03773 Predicted permease SPy_0580 PF00575 S1 RNA binding domain SPy_0580 PF09371 Tex-like protein N-terminal domain SPy_0580 PF17674 HHH domain SPy_0580 PF16921 Tex protein YqgF-like domain SPy_0581 PF10263 SprT-like family SPy_0584 PF02603 HPr Serine kinase N terminus SPy_0584 PF07475 HPr Serine kinase C-terminal domain SPy_0585 PF01790 Prolipoprotein diacylglyceryl transferase SPy_0588 PF12732 YtxH-like protein SPy_0591 PF01136 Peptidase family U32 SPy_0591 PF16325 Peptidase family U32 C-terminal domain SPy_0593 PF02229 Transcriptional Coactivator p15 (PC4) SPy_0595 PF00152 tRNA synthetases class II (D, K and N) SPy_0595 PF01336 OB-fold nucleic acid binding domain SPy_0600 PF09515 Thiamine transporter protein (Thia_YuaJ) SPy_0605 PF00255 Glutathione peroxidase SPy_0606 PF01432 Peptidase family M3 SPy_0606 PF08439 Oligopeptidase F SPy_0608 PF00311 Phosphoenolpyruvate carboxylase SPy_0609 PF01098 Cell cycle protein SPy_0611 PF03143 Elongation factor Tu C-terminal domain SPy_0611 PF00009 Elongation factor Tu GTP binding domain SPy_0611 PF03144 Elongation factor Tu domain 2 SPy_0613 PF00121 Triosephosphate isomerase SPy_0621 PF01966 HD domain SPy_0623 PF00690 Cation transporter/ATPase, N-terminus SPy_0623 PF00689 Cation transporting ATPase, C-terminus SPy_0627 PF00356 Bacterial regulatory proteins, lacI family SPy_0629 PF03613 PTS system mannose/fructose/sorbose family IID component SPy_0630 PF03609 PTS system sorbose-specific iic component SPy_0631 PF03830 PTS system sorbose subfamily IIB component SPy_0632 PF07470 Glycosyl Hydrolase Family 88 SPy_0639 PF01081 KDPG and KHG aldolase SPy_0640 PF13419 Haloacid dehalogenase-like hydrolase SPy_0642 PF08331 Domain of unknown function (DUF1730) SPy_0643 PF03462 PCRF domain SPy_0643 PF00472 RF-1 domain SPy_0644 PF00005 ABC transporter SPy_0645 PF18075 FtsX extracellular domain SPy_0645 PF02687 FtsX-like permease family SPy_0646 PF00753 Metallo-beta-lactamase superfamily SPy_0649 PF13307 Helicase C-terminal domain SPy_0649 PF00929 Exonuclease SPy_0649 PF04851 Type III restriction enzyme, res subunit SPy_0650 PF00155 Aminotransferase class I and II SPy_0651 PF00152 tRNA synthetases class II (D, K and N) SPy_0651 PF01336 OB-fold nucleic acid binding domain SPy_0652 PF03668 P-loop ATPase protein family SPy_0653 PF01933 Uncharacterised protein family UPF0052 SPy_0654 PF02650 WhiA C-terminal HTH domain SPy_0654 PF14527 WhiA LAGLIDADG-like domain SPy_0654 PF10298 WhiA N-terminal LAGLIDADG-like domain SPy_0655 PF00239 Resolvase, N terminal domain SPy_0655 PF02796 Helix-turn-helix domain of resolvase SPy_0679 PF02195 ParB-like nuclease domain SPy_0710 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPy_0710 PF13457 GW (Gly-Tryp) dipeptide domain SPy_0711 PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain SPy_0711 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_0713 PF03577 Peptidase family C69 SPy_0714 PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment SPy_0714 PF01297 Zinc-uptake complex component A periplasmic SPy_0715 PF00392 Bacterial regulatory proteins, gntR family SPy_0715 PF07702 UTRA domain SPy_0716 PF01380 SIS domain SPy_0717 PF01197 Ribosomal protein L31 SPy_0720 PF01368 DHH family SPy_0720 PF02272 DHHA1 domain SPy_0721 PF00258 Flavodoxin SPy_0723 PF00654 Voltage gated chloride channel SPy_0724 PF01245 Ribosomal protein L19 SPy_0727 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0727 PF00204 DNA gyrase B SPy_0727 PF01751 Toprim domain SPy_0727 PF00986 DNA gyrase B subunit, carboxyl terminus SPy_0728 PF06160 Septation ring formation regulator, EzrA SPy_0731 PF03952 Enolase, N-terminal domain SPy_0731 PF00113 Enolase, C-terminal TIM barrel domain SPy_0744 PF00005 ABC transporter SPy_0749 PF06177 QueT transporter SPy_0751 PF03120 NAD-dependent DNA ligase OB-fold domain SPy_0751 PF03119 NAD-dependent DNA ligase C4 zinc finger domain SPy_0751 PF12826 Helix-hairpin-helix motif SPy_0751 PF00533 BRCA1 C Terminus (BRCT) domain SPy_0751 PF01653 NAD-dependent DNA ligase adenylation domain SPy_0752 PF00781 Diacylglycerol kinase catalytic domain SPy_0754 PF00137 ATP synthase subunit C SPy_0755 PF00119 ATP synthase A chain SPy_0756 PF00430 ATP synthase B/B' CF(0) SPy_0757 PF00213 ATP synthase delta (OSCP) subunit SPy_0758 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPy_0758 PF00306 ATP synthase alpha/beta chain, C terminal domain SPy_0758 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPy_0759 PF00231 ATP synthase SPy_0760 PF02874 ATP synthase alpha/beta family, beta-barrel domain SPy_0760 PF00006 ATP synthase alpha/beta family, nucleotide-binding domain SPy_0761 PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain SPy_0761 PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain SPy_0763 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPy_0766 PF01223 DNA/RNA non-specific endonuclease SPy_0768 PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain SPy_0768 PF01409 tRNA synthetases class II core domain (F) SPy_0769 PF03484 tRNA synthetase B5 domain SPy_0769 PF17759 Phenylalanyl tRNA synthetase beta chain CLM domain SPy_0769 PF03483 B3/4 domain SPy_0769 PF03147 Ferredoxin-fold anticodon binding domain SPy_0769 PF01588 Putative tRNA binding domain SPy_0772 PF02687 FtsX-like permease family SPy_0773 PF00005 ABC transporter SPy_0775 PF04228 Putative neutral zinc metallopeptidase SPy_0776 PF12705 PD-(D/E)XK nuclease superfamily SPy_0777 PF13361 UvrD-like helicase C-terminal domain SPy_0777 PF00580 UvrD/REP helicase N-terminal domain SPy_0777 PF12705 PD-(D/E)XK nuclease superfamily SPy_0778 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPy_0779 PF01165 Ribosomal protein S21 SPy_0780 PF01741 Large-conductance mechanosensitive channel, MscL SPy_0781 PF01807 CHC2 zinc finger SPy_0781 PF10410 DnaB-helicase binding domain of primase SPy_0781 PF08275 DNA primase catalytic core, N-terminal domain SPy_0782 PF04539 Sigma-70 region 3 SPy_0782 PF04545 Sigma-70, region 4 SPy_0782 PF00140 Sigma-70 factor, region 1.2 SPy_0782 PF03979 Sigma-70 factor, region 1.1 SPy_0782 PF04542 Sigma-70 region 2 SPy_0783 PF01883 Iron-sulfur cluster assembly protein SPy_0784 PF04321 RmlD substrate binding domain SPy_0787 PF02709 N-terminal domain of galactosyltransferase SPy_0787 PF00535 Glycosyl transferase family 2 SPy_0790 PF00005 ABC transporter SPy_0791 PF00535 Glycosyl transferase family 2 SPy_0794 PF00535 Glycosyl transferase family 2 SPy_0799 PF01546 Peptidase family M20/M25/M40 SPy_0799 PF07687 Peptidase dimerisation domain SPy_0803 PF02224 Cytidylate kinase SPy_0804 PF05198 Translation initiation factor IF-3, N-terminal domain SPy_0804 PF00707 Translation initiation factor IF-3, C-terminal domain SPy_0805 PF01632 Ribosomal protein L35 SPy_0806 PF00453 Ribosomal protein L20 SPy_0807 PF00884 Sulfatase SPy_0808 PF10672 S-adenosylmethionine-dependent methyltransferase SPy_0808 PF17785 PUA-like domain SPy_0809 PF01487 Type I 3-dehydroquinase SPy_0810 PF01264 Chorismate synthase SPy_0811 PF06133 Control of competence regulator ComK, YlbF/YmcA SPy_0813 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPy_0813 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_0814 PF02875 Mur ligase family, glutamate ligase domain SPy_0814 PF08245 Mur ligase middle domain SPy_0816 PF00266 Aminotransferase class-V SPy_0817 PF02926 THUMP domain SPy_0817 PF02568 Thiamine biosynthesis protein (ThiI) SPy_0818 PF09587 Bacterial capsule synthesis protein PGA_cap SPy_0819 PF00829 Ribosomal prokaryotic L21 protein SPy_0822 PF01016 Ribosomal L27 protein SPy_0824 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPy_0824 PF03466 LysR substrate binding domain SPy_0826 PF01252 Signal peptidase (SPase) II SPy_0827 PF01479 S4 domain SPy_0827 PF00849 RNA pseudouridylate synthase SPy_0830 PF00156 Phosphoribosyl transferase domain SPy_0831 PF00860 Permease family SPy_0832 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPy_0832 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPy_0833 PF00117 Glutamine amidotransferase class-I SPy_0833 PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain SPy_0835 PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain SPy_0835 PF02142 MGS-like domain SPy_0835 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPy_0836 PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion SPy_0837 PF00005 ABC transporter SPy_0838 PF12704 MacB-like periplasmic core domain SPy_0838 PF02687 FtsX-like permease family SPy_0839 PF03009 Glycerophosphoryl diester phosphodiesterase family SPy_0840 PF00886 Ribosomal protein S16 SPy_0847 PF05239 PRC-barrel domain SPy_0847 PF01782 RimM N-terminal domain SPy_0849 PF01746 tRNA (Guanine-1)-methyltransferase SPy_0850 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_0852 PF08546 Ketopantoate reductase PanE/ApbA C terminal SPy_0852 PF02558 Ketopantoate reductase PanE/ApbA SPy_0853 PF00455 DeoR C terminal sensor domain SPy_0853 PF08220 DeoR-like helix-turn-helix domain SPy_0854 PF00294 pfkB family carbohydrate kinase SPy_0855 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPy_0855 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_0856 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPy_0856 PF01476 LysM domain SPy_0857 PF01476 LysM domain SPy_0857 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPy_0861 PF09028 Mac 1 SPy_0865 PF02645 Uncharacterised protein, DegV family COG1307 SPy_0866 PF01743 Poly A polymerase head domain SPy_0866 PF13735 tRNA nucleotidyltransferase domain 2 putative SPy_0866 PF12627 Probable RNA and SrmB- binding site of polymerase A SPy_0867 PF16326 ABC transporter C-terminal domain SPy_0867 PF00005 ABC transporter SPy_0867 PF12848 ABC transporter SPy_0870 PF01327 Polypeptide deformylase SPy_0872 PF00149 Calcineurin-like phosphoesterase SPy_0872 PF17936 Bacterial Ig domain SPy_0872 PF02872 5'-nucleotidase, C-terminal domain SPy_0873 PF04607 Region found in RelA / SpoT proteins SPy_0874 PF00072 Response regulator receiver domain SPy_0874 PF00486 Transcriptional regulatory protein, C terminal SPy_0875 PF00512 His Kinase A (phospho-acceptor) domain SPy_0875 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0876 PF08544 GHMP kinases C terminal SPy_0876 PF10509 Galactokinase galactose-binding signature SPy_0876 PF00288 GHMP kinases N terminal domain SPy_0878 PF00288 GHMP kinases N terminal domain SPy_0878 PF08544 GHMP kinases C terminal SPy_0879 PF01070 FMN-dependent dehydrogenase SPy_0880 PF00368 Hydroxymethylglutaryl-coenzyme A reductase SPy_0881 PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal SPy_0881 PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal SPy_0882 PF00303 Thymidylate synthase SPy_0883 PF00186 Dihydrofolate reductase SPy_0885 PF06689 ClpX C4-type zinc finger SPy_0885 PF07724 AAA domain (Cdc48 subfamily) SPy_0885 PF10431 C-terminal, D2-small domain, of ClpB protein SPy_0886 PF01926 50S ribosome-binding GTPase SPy_0888 PF00004 ATPase family associated with various cellular activities (AAA) SPy_0888 PF17871 AAA lid domain SPy_0888 PF10431 C-terminal, D2-small domain, of ClpB protein SPy_0888 PF07724 AAA domain (Cdc48 subfamily) SPy_0889 PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) SPy_0890 PF01676 Metalloenzyme superfamily SPy_0891 PF03960 ArsC family SPy_0892 PF01048 Phosphorylase superfamily SPy_0894 PF01048 Phosphorylase superfamily SPy_0898 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPy_0898 PF03466 LysR substrate binding domain SPy_0900 PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family SPy_0901 PF00156 Phosphoribosyl transferase domain SPy_0902 PF01425 Amidase SPy_0903 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPy_0904 PF00528 Binding-protein-dependent transport system inner membrane component SPy_0905 PF03167 Uracil DNA glycosylase superfamily SPy_0907 PF01979 Amidohydrolase family SPy_0908 PF02660 Glycerol-3-phosphate acyltransferase SPy_0909 PF00986 DNA gyrase B subunit, carboxyl terminus SPy_0909 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_0909 PF01751 Toprim domain SPy_0909 PF00204 DNA gyrase B SPy_0910 PF03989 DNA gyrase C-terminal domain, beta-propeller SPy_0910 PF00521 DNA gyrase/topoisomerase IV, subunit A SPy_0911 PF01063 Amino-transferase class IV SPy_0913 PF00575 S1 RNA binding domain SPy_0915 PF00581 Rhodanese-like domain SPy_0915 PF12368 Rhodanase C-terminal SPy_0915 PF17773 UPF0176 acylphosphatase like domain SPy_0922 PF13167 GTP-binding GTPase N-terminal SPy_0922 PF01926 50S ribosome-binding GTPase SPy_0922 PF16360 GTP-binding GTPase Middle Region SPy_0923 PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain SPy_0923 PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain SPy_0924 PF12706 Beta-lactamase superfamily domain SPy_0924 PF00753 Metallo-beta-lactamase superfamily SPy_0925 PF00106 short chain dehydrogenase SPy_0926 PF01368 DHH family SPy_0926 PF10141 Single-strand DNA-specific exonuclease, C terminal domain SPy_0926 PF17768 RecJ OB domain SPy_0926 PF02272 DHHA1 domain SPy_0927 PF00156 Phosphoribosyl transferase domain SPy_0929 PF10576 Iron-sulfur binding domain of endonuclease III SPy_0929 PF00633 Helix-hairpin-helix motif SPy_0929 PF00730 HhH-GPD superfamily base excision DNA repair protein SPy_0930 PF04816 tRNA (adenine(22)-N(1))-methyltransferase SPy_0931 PF01784 NIF3 (NGG1p interacting factor 3) SPy_0932 PF01266 FAD dependent oxidoreductase SPy_0933 PF00483 Nucleotidyl transferase SPy_0935 PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase SPy_0936 PF16363 GDP-mannose 4,6 dehydratase SPy_0937 PF00589 Phage integrase family SPy_0937 PF14659 Phage integrase, N-terminal SAM-like domain SPy_0939 PF01381 Helix-turn-helix SPy_0946 PF10548 P22AR C-terminal domain SPy_0946 PF08346 AntA/AntB antirepressor SPy_1007 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_1008 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_1008 PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain SPy_1010 PF00293 NUDIX domain SPy_1011 PF01594 AI-2E family transporter SPy_1013 PF05670 NFACT protein RNA binding domain SPy_1019 PF00005 ABC transporter SPy_1020 PF00753 Metallo-beta-lactamase superfamily SPy_1020 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPy_1020 PF17770 Ribonuclease J C-terminal domain SPy_1022 PF00756 Putative esterase SPy_1025 PF12848 ABC transporter SPy_1025 PF16326 ABC transporter C-terminal domain SPy_1025 PF00005 ABC transporter SPy_1026 PF00676 Dehydrogenase E1 component SPy_1028 PF02779 Transketolase, pyrimidine binding domain SPy_1028 PF00364 Biotin-requiring enzyme SPy_1028 PF02780 Transketolase, C-terminal domain SPy_1029 PF02817 e3 binding domain SPy_1029 PF00364 Biotin-requiring enzyme SPy_1029 PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) SPy_1031 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_1031 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPy_1032 PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain SPy_1032 PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain SPy_1032 PF02278 Polysaccharide lyase family 8, super-sandwich domain SPy_1033 PF10437 Bacterial lipoate protein ligase C-terminus SPy_1033 PF03099 Biotin/lipoate A/B protein ligase family SPy_1034 PF07685 CobB/CobQ-like glutamine amidotransferase domain SPy_1035 PF08353 Domain of unknown function (DUF1727) SPy_1035 PF08245 Mur ligase middle domain SPy_1036 PF02457 DisA bacterial checkpoint controller nucleotide-binding SPy_1038 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPy_1038 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPy_1038 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPy_1038 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPy_1040 PF06969 HemN C-terminal domain SPy_1040 PF04055 Radical SAM superfamily SPy_1043 PF13344 Haloacid dehalogenase-like hydrolase SPy_1046 PF16592 REC lobe of CRISPR-associated endonuclease Cas9 SPy_1046 PF16595 PAM-interacting domain of CRISPR-associated endonuclease Cas9 SPy_1046 PF13395 HNH endonuclease SPy_1046 PF16593 Bridge helix of CRISPR-associated endonuclease Cas9 SPy_1047 PF01867 CRISPR associated protein Cas1 SPy_1048 PF09827 CRISPR associated protein Cas2 SPy_1049 PF09711 CRISPR-associated protein (Cas_Csn2) SPy_1053 PF06421 GTP-binding protein LepA C-terminus SPy_1053 PF00009 Elongation factor Tu GTP binding domain SPy_1053 PF03144 Elongation factor Tu domain 2 SPy_1053 PF14492 Elongation Factor G, domain II SPy_1053 PF00679 Elongation factor G C-terminus SPy_1054 PF00746 LPXTG cell wall anchor motif SPy_1054 PF02370 M protein repeat SPy_1055 PF01641 SelR domain SPy_1056 PF03601 Conserved hypothetical protein 698 SPy_1058 PF03830 PTS system sorbose subfamily IIB component SPy_1059 PF03609 PTS system sorbose-specific iic component SPy_1060 PF03613 PTS system mannose/fructose/sorbose family IID component SPy_1061 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1061 PF06580 Histidine kinase SPy_1062 PF12833 Helix-turn-helix domain SPy_1062 PF00072 Response regulator receiver domain SPy_1065 PF00132 Bacterial transferase hexapeptide (six repeats) SPy_1065 PF12464 Maltose acetyltransferase SPy_1065 PF14602 Hexapeptide repeat of succinyl-transferase SPy_1066 PF13419 Haloacid dehalogenase-like hydrolase SPy_1067 PF00171 Aldehyde dehydrogenase family SPy_1068 PF08459 UvrC Helix-hairpin-helix N-terminal SPy_1068 PF01541 GIY-YIG catalytic domain SPy_1068 PF02151 UvrB/uvrC motif SPy_1069 PF00881 Nitroreductase family SPy_1070 PF01546 Peptidase family M20/M25/M40 SPy_1071 PF10396 GTP-binding protein TrmE N-terminus SPy_1071 PF01926 50S ribosome-binding GTPase SPy_1071 PF12631 MnmE helical domain SPy_1072 PF00466 Ribosomal protein L10 SPy_1073 PF00542 Ribosomal protein L7/L12 C-terminal domain SPy_1073 PF16320 Ribosomal protein L7/L12 dimerisation domain SPy_1077 PF00145 C-5 cytosine-specific DNA methylase SPy_1081 PF00486 Transcriptional regulatory protein, C terminal SPy_1081 PF00072 Response regulator receiver domain SPy_1082 PF00512 His Kinase A (phospho-acceptor) domain SPy_1082 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1084 PF00005 ABC transporter SPy_1085 PF00005 ABC transporter SPy_1088 PF01381 Helix-turn-helix SPy_1093 PF07943 Penicillin-binding protein 5, C-terminal domain SPy_1093 PF00768 D-alanyl-D-alanine carboxypeptidase SPy_1096 PF08245 Mur ligase middle domain SPy_1096 PF02875 Mur ligase family, glutamate ligase domain SPy_1097 PF01227 GTP cyclohydrolase I SPy_1098 PF00809 Pterin binding enzyme SPy_1099 PF02152 Dihydroneopterin aldolase SPy_1100 PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) SPy_1101 PF01565 FAD binding domain SPy_1101 PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain SPy_1102 PF08402 TOBE domain SPy_1102 PF00005 ABC transporter SPy_1103 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1104 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1105 PF13416 Bacterial extracellular solute-binding protein SPy_1106 PF00072 Response regulator receiver domain SPy_1107 PF00989 PAS fold SPy_1107 PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain SPy_1107 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1107 PF17203 Single cache domain 3 SPy_1109 PF03390 2-hydroxycarboxylate transporter family SPy_1110 PF03949 Malic enzyme, NAD binding domain SPy_1110 PF00390 Malic enzyme, N-terminal domain SPy_1111 PF08240 Alcohol dehydrogenase GroES-like domain SPy_1111 PF00107 Zinc-binding dehydrogenase SPy_1111 PF13823 Alcohol dehydrogenase GroES-associated SPy_1113 PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) SPy_1114 PF00654 Voltage gated chloride channel SPy_1117 PF01594 AI-2E family transporter SPy_1118 PF04002 RadC-like JAB domain SPy_1119 PF07722 Peptidase C26 SPy_1120 PF02629 CoA binding domain SPy_1120 PF06971 Putative DNA-binding protein N-terminus SPy_1122 PF00266 Aminotransferase class-V SPy_1123 PF13793 N-terminal domain of ribose phosphate pyrophosphokinase SPy_1123 PF14572 Phosphoribosyl synthetase-associated domain SPy_1125 PF04607 Region found in RelA / SpoT proteins SPy_1126 PF01513 ATP-NAD kinase SPy_1127 PF00849 RNA pseudouridylate synthase SPy_1127 PF01479 S4 domain SPy_1128 PF01515 Phosphate acetyl/butaryl transferase SPy_1133 PF00005 ABC transporter SPy_1133 PF00571 CBS domain SPy_1134 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1135 PF00478 IMP dehydrogenase / GMP reductase domain SPy_1136 PF00156 Phosphoribosyl transferase domain SPy_1137 PF00860 Permease family SPy_1138 PF02424 ApbE family SPy_1139 PF01361 Tautomerase enzyme SPy_1140 PF00265 Thymidine kinase SPy_1141 PF03462 PCRF domain SPy_1141 PF00472 RF-1 domain SPy_1142 PF05175 Methyltransferase small domain SPy_1145 PF00464 Serine hydroxymethyltransferase SPy_1148 PF00005 ABC transporter SPy_1148 PF00664 ABC transporter transmembrane region SPy_1149 PF00005 ABC transporter SPy_1149 PF00664 ABC transporter transmembrane region SPy_1150 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPy_1150 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_1151 PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain SPy_1151 PF00056 lactate/malate dehydrogenase, NAD binding domain SPy_1152 PF03989 DNA gyrase C-terminal domain, beta-propeller SPy_1152 PF00521 DNA gyrase/topoisomerase IV, subunit A SPy_1154 PF04203 Sortase domain SPy_1155 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPy_1159 PF03006 Haemolysin-III related SPy_1161 PF01926 50S ribosome-binding GTPase SPy_1162 PF01351 Ribonuclease HII SPy_1163 PF18255 DNA processing protein A sterile alpha motif domain SPy_1163 PF02481 DNA recombination-mediator protein A SPy_1164 PF01131 DNA topoisomerase SPy_1164 PF01751 Toprim domain SPy_1164 PF01396 Topoisomerase DNA binding C4 zinc finger SPy_1170 PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SPy_1170 PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain SPy_1173 PF01134 Glucose inhibited division protein A SPy_1174 PF00364 Biotin-requiring enzyme SPy_1174 PF00682 HMGL-like SPy_1174 PF02436 Conserved carboxylase domain SPy_1176 PF00364 Biotin-requiring enzyme SPy_1177 PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit SPy_1178 PF01874 ATP:dephospho-CoA triphosphoribosyl transferase SPy_1180 PF03600 Citrate transporter SPy_1183 PF00364 Biotin-requiring enzyme SPy_1184 PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit SPy_1186 PF06857 Malonate decarboxylase delta subunit (MdcD) SPy_1188 PF03328 HpcH/HpaI aldolase/citrate lyase family SPy_1189 PF04223 Citrate lyase, alpha subunit (CitF) SPy_1190 PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase SPy_1191 PF02436 Conserved carboxylase domain SPy_1191 PF00364 Biotin-requiring enzyme SPy_1191 PF00682 HMGL-like SPy_1192 PF08218 Citrate lyase ligase C-terminal domain SPy_1196 PF00589 Phage integrase family SPy_1196 PF13495 Phage integrase, N-terminal SAM-like domain SPy_1200 PF00448 SRP54-type protein, GTPase domain SPy_1200 PF02978 Signal peptide binding domain SPy_1200 PF02881 SRP54-type protein, helical bundle domain SPy_1201 PF04297 Putative helix-turn-helix protein, YlxM / p13 like SPy_1202 PF00392 Bacterial regulatory proteins, gntR family SPy_1202 PF07702 UTRA domain SPy_1204 PF02540 NAD synthase SPy_1204 PF00958 GMP synthase C terminal domain SPy_1204 PF00117 Glutamine amidotransferase class-I SPy_1206 PF00005 ABC transporter SPy_1206 PF12848 ABC transporter SPy_1209 PF08543 Phosphomethylpyrimidine kinase SPy_1209 PF02581 Thiamine monophosphate synthase SPy_1210 PF00155 Aminotransferase class I and II SPy_1210 PF00392 Bacterial regulatory proteins, gntR family SPy_1211 PF03477 ATP cone domain SPy_1211 PF13597 Anaerobic ribonucleoside-triphosphate reductase SPy_1212 PF13091 PLD-like domain SPy_1213 PF01268 Formate--tetrahydrofolate ligase SPy_1214 PF03099 Biotin/lipoate A/B protein ligase family SPy_1214 PF10437 Bacterial lipoate protein ligase C-terminus SPy_1216 PF01661 Macro domain SPy_1217 PF01597 Glycine cleavage H-protein SPy_1218 PF00296 Luciferase-like monooxygenase SPy_1219 PF00724 NADH:flavin oxidoreductase / NADH oxidase family SPy_1220 PF03099 Biotin/lipoate A/B protein ligase family SPy_1221 PF02441 Flavoprotein SPy_1221 PF04127 DNA / pantothenate metabolism flavoprotein SPy_1222 PF02441 Flavoprotein SPy_1223 PF12822 ECF transporter, substrate-specific component SPy_1224 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPy_1224 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPy_1224 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPy_1224 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPy_1225 PF02653 Branched-chain amino acid transport system / permease component SPy_1226 PF02653 Branched-chain amino acid transport system / permease component SPy_1227 PF00005 ABC transporter SPy_1228 PF02608 ABC transporter substrate-binding protein PnrA-like SPy_1230 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPy_1232 PF05175 Methyltransferase small domain SPy_1233 PF00485 Phosphoribulokinase / Uridine kinase family SPy_1234 PF01649 Ribosomal protein S20 SPy_1236 PF00512 His Kinase A (phospho-acceptor) domain SPy_1236 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1237 PF00072 Response regulator receiver domain SPy_1237 PF00486 Transcriptional regulatory protein, C terminal SPy_1239 PF11838 ERAP1-like C-terminal domain SPy_1239 PF01433 Peptidase family M1 domain SPy_1240 PF01895 PhoU domain SPy_1241 PF00005 ABC transporter SPy_1242 PF00005 ABC transporter SPy_1243 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1244 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1245 PF12849 PBP superfamily domain SPy_1246 PF17126 RsmF rRNA methyltransferase first C-terminal domain SPy_1246 PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF SPy_1246 PF01189 16S rRNA methyltransferase RsmB/F SPy_1247 PF00459 Inositol monophosphatase family SPy_1248 PF05256 Uncharacterised protein family (UPF0223) SPy_1249 PF03960 ArsC family SPy_1250 PF01687 Riboflavin kinase SPy_1250 PF06574 FAD synthetase SPy_1251 PF01509 TruB family pseudouridylate synthase (N terminal domain) SPy_1251 PF16198 tRNA pseudouridylate synthase B C-terminal domain SPy_1257 PF02687 FtsX-like permease family SPy_1257 PF12704 MacB-like periplasmic core domain SPy_1257 PF00005 ABC transporter SPy_1260 PF03780 Asp23 family, cell envelope-related function SPy_1261 PF05532 CsbD-like SPy_1262 PF03780 Asp23 family, cell envelope-related function SPy_1267 PF00580 UvrD/REP helicase N-terminal domain SPy_1267 PF13361 UvrD-like helicase C-terminal domain SPy_1270 PF01235 Sodium:alanine symporter family SPy_1272 PF16916 Dimerisation domain of Zinc Transporter SPy_1272 PF01545 Cation efflux family SPy_1273 PF07373 CAMP factor (Cfa) SPy_1274 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPy_1275 PF00005 ABC transporter SPy_1276 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1277 PF08274 PhnA Zinc-Ribbon SPy_1277 PF03831 PhnA domain SPy_1280 PF01380 SIS domain SPy_1281 PF10502 Signal peptidase, peptidase S26 SPy_1282 PF02887 Pyruvate kinase, alpha/beta domain SPy_1282 PF00224 Pyruvate kinase, barrel domain SPy_1283 PF00365 Phosphofructokinase SPy_1284 PF01336 OB-fold nucleic acid binding domain SPy_1284 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPy_1284 PF02811 PHP domain SPy_1284 PF14579 Helix-hairpin-helix motif SPy_1284 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPy_1285 PF00392 Bacterial regulatory proteins, gntR family SPy_1286 PF00005 ABC transporter SPy_1291 PF00343 Carbohydrate phosphorylase SPy_1292 PF02446 4-alpha-glucanotransferase SPy_1293 PF00356 Bacterial regulatory proteins, lacI family SPy_1293 PF00532 Periplasmic binding proteins and sugar binding domain of LacI family SPy_1294 PF13416 Bacterial extracellular solute-binding protein SPy_1295 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1296 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1297 PF00356 Bacterial regulatory proteins, lacI family SPy_1299 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1301 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1302 PF01833 IPT/TIG domain SPy_1302 PF00128 Alpha amylase, catalytic domain SPy_1302 PF00686 Starch binding domain SPy_1304 PF02903 Alpha amylase, N-terminal ig-like domain SPy_1304 PF00128 Alpha amylase, catalytic domain SPy_1306 PF13416 Bacterial extracellular solute-binding protein SPy_1308 PF00934 PE family SPy_1308 PF07859 alpha/beta hydrolase fold SPy_1309 PF04914 DltD protein SPy_1310 PF00550 Phosphopantetheine attachment site SPy_1311 PF03062 MBOAT, membrane-bound O-acyltransferase family SPy_1312 PF13193 AMP-binding enzyme C-terminal domain SPy_1312 PF00501 AMP-binding enzyme SPy_1314 PF17757 UvrB interaction domain SPy_1314 PF12344 Ultra-violet resistance protein B SPy_1314 PF02151 UvrB/uvrC motif SPy_1314 PF04851 Type III restriction enzyme, res subunit SPy_1314 PF00271 Helicase conserved C-terminal domain SPy_1315 PF00497 Bacterial extracellular solute-binding proteins, family 3 SPy_1316 PF00005 ABC transporter SPy_1323 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPy_1324 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_1325 PF05043 Mga helix-turn-helix domain SPy_1325 PF00874 PRD domain SPy_1325 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPy_1325 PF08279 HTH domain SPy_1328 PF00232 Glycosyl hydrolase family 1 SPy_1333 PF09269 Domain of unknown function (DUF1967) SPy_1333 PF01018 GTP1/OBG SPy_1333 PF01926 50S ribosome-binding GTPase SPy_1336 PF00665 Integrase core domain SPy_1336 PF13333 Integrase core domain SPy_1336 PF13276 HTH-like domain SPy_1337 PF01479 S4 domain SPy_1337 PF00849 RNA pseudouridylate synthase SPy_1340 PF07690 Major Facilitator Superfamily SPy_1343 PF08903 Domain of unknown function (DUF1846) SPy_1346 PF01938 TRAM domain SPy_1346 PF05958 tRNA (Uracil-5-)-methyltransferase SPy_1350 PF03816 Cell envelope-related transcriptional attenuator domain SPy_1351 PF01202 Shikimate kinase SPy_1352 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPy_1354 PF00557 Metallopeptidase family M24 SPy_1355 PF00392 Bacterial regulatory proteins, gntR family SPy_1355 PF07085 DRTGG domain SPy_1355 PF00571 CBS domain SPy_1355 PF03061 Thioesterase superfamily SPy_1356 PF13302 Acetyltransferase (GNAT) domain SPy_1357 PF00746 LPXTG cell wall anchor motif SPy_1357 PF17573 GA-like domain SPy_1357 PF00746 LPXTG cell wall anchor motif SPy_1357 PF17573 GA-like domain SPy_1357 PF01378 B domain SPy_1357 PF01378 B domain SPy_1358 PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) SPy_1359 PF02773 S-adenosylmethionine synthetase, C-terminal domain SPy_1359 PF00438 S-adenosylmethionine synthetase, N-terminal domain SPy_1359 PF02772 S-adenosylmethionine synthetase, central domain SPy_1362 PF08279 HTH domain SPy_1362 PF02237 Biotin protein ligase C terminal domain SPy_1362 PF03099 Biotin/lipoate A/B protein ligase family SPy_1364 PF12169 DNA polymerase III subunits gamma and tau domain III SPy_1365 PF13185 GAF domain SPy_1368 PF00485 Phosphoribulokinase / Uridine kinase family SPy_1369 PF00271 Helicase conserved C-terminal domain SPy_1369 PF00270 DEAD/DEAH box helicase SPy_1370 PF18627 Peptidoglycan GlcNAc deacetylase N-terminal domain SPy_1370 PF01522 Polysaccharide deacetylase SPy_1371 PF00171 Aldehyde dehydrogenase family SPy_1372 PF02896 PEP-utilising enzyme, TIM barrel domain SPy_1372 PF05524 PEP-utilising enzyme, N-terminal SPy_1372 PF00391 PEP-utilising enzyme, mobile domain SPy_1373 PF00381 PTS HPr component phosphorylation site SPy_1374 PF00462 Glutaredoxin SPy_1375 PF02867 Ribonucleotide reductase, barrel domain SPy_1375 PF08343 Ribonucleotide reductase N-terminal SPy_1375 PF00317 Ribonucleotide reductase, all-alpha domain SPy_1378 PF00268 Ribonucleotide reductase, small chain SPy_1386 PF01381 Helix-turn-helix SPy_1389 PF07973 Threonyl and Alanyl tRNA synthetase second additional domain SPy_1389 PF01411 tRNA synthetases class II (A) SPy_1389 PF02272 DHHA1 domain SPy_1390 PF13145 PPIC-type PPIASE domain SPy_1391 PF01596 O-methyltransferase SPy_1392 PF07690 Major Facilitator Superfamily SPy_1393 PF08439 Oligopeptidase F SPy_1393 PF01432 Peptidase family M3 SPy_1398 PF00849 RNA pseudouridylate synthase SPy_1398 PF01479 S4 domain SPy_1399 PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SPy_1400 PF02547 Queuosine biosynthesis protein SPy_1406 PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain SPy_1406 PF02777 Iron/manganese superoxide dismutases, C-terminal domain SPy_1408 PF03772 Competence protein SPy_1408 PF00753 Metallo-beta-lactamase superfamily SPy_1408 PF13567 Domain of unknown function (DUF4131) SPy_1409 PF10531 SLBB domain SPy_1410 PF01553 Acyltransferase SPy_1411 PF05175 Methyltransferase small domain SPy_1412 PF01541 GIY-YIG catalytic domain SPy_1414 PF02705 K+ potassium transporter SPy_1415 PF00270 DEAD/DEAH box helicase SPy_1415 PF00271 Helicase conserved C-terminal domain SPy_1416 PF16658 Class II release factor RF3, C-terminal domain SPy_1416 PF03144 Elongation factor Tu domain 2 SPy_1416 PF00009 Elongation factor Tu GTP binding domain SPy_1420 PF08245 Mur ligase middle domain SPy_1420 PF01225 Mur ligase family, catalytic domain SPy_1420 PF02875 Mur ligase family, glutamate ligase domain SPy_1421 PF07478 D-ala D-ala ligase C-terminus SPy_1421 PF01820 D-ala D-ala ligase N-terminus SPy_1422 PF02132 RecR protein SPy_1422 PF13662 Toprim domain SPy_1423 PF00905 Penicillin binding protein transpeptidase domain SPy_1423 PF03717 Penicillin-binding Protein dimerisation domain SPy_1424 PF01226 Formate/nitrite transporter SPy_1427 PF08279 HTH domain SPy_1427 PF02829 3H domain SPy_1429 PF00300 Histidine phosphatase superfamily (branch 1) SPy_1432 PF01180 Dihydroorotate dehydrogenase SPy_1477 PF03837 RecT family SPy_1486 PF01381 Helix-turn-helix SPy_1488 PF00589 Phage integrase family SPy_1488 PF14659 Phage integrase, N-terminal SAM-like domain SPy_1489 PF00216 Bacterial DNA-binding protein SPy_1492 PF13472 GDSL-like Lipase/Acylhydrolase family SPy_1493 PF02645 Uncharacterised protein, DegV family COG1307 SPy_1495 PF13476 AAA domain SPy_1496 PF01316 Arginine repressor, DNA binding domain SPy_1496 PF02863 Arginine repressor, C-terminal domain SPy_1497 PF01728 FtsJ-like methyltransferase SPy_1497 PF01479 S4 domain SPy_1498 PF00348 Polyprenyl synthetase SPy_1499 PF02609 Exonuclease VII small subunit SPy_1500 PF02601 Exonuclease VII, large subunit SPy_1500 PF13742 OB-fold nucleic acid binding domain SPy_1502 PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain SPy_1502 PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SPy_1503 PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I SPy_1503 PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain SPy_1503 PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III SPy_1503 PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II SPy_1505 PF00875 DNA photolyase SPy_1505 PF03441 FAD binding domain of DNA photolyase SPy_1506 PF00005 ABC transporter SPy_1507 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1508 PF08796 Protein of unknown function (DUF1797) SPy_1509 PF07724 AAA domain (Cdc48 subfamily) SPy_1509 PF17871 AAA lid domain SPy_1509 PF10431 C-terminal, D2-small domain, of ClpB protein SPy_1509 PF00004 ATPase family associated with various cellular activities (AAA) SPy_1510 PF00293 NUDIX domain SPy_1513 PF08264 Anticodon-binding domain of tRNA SPy_1513 PF00133 tRNA synthetases class I (I, L, M and V) SPy_1514 PF05103 DivIVA protein SPy_1515 PF01479 S4 domain SPy_1515 PF17774 Putative RNA-binding domain in YlmH SPy_1518 PF04472 Cell division protein SepF SPy_1519 PF01168 Alanine racemase, N-terminal domain SPy_1520 PF12327 FtsZ family, C-terminal domain SPy_1520 PF00091 Tubulin/FtsZ family, GTPase domain SPy_1521 PF11983 Membrane-attachment and polymerisation-promoting switch SPy_1521 PF02491 SHS2 domain inserted in FTSA SPy_1523 PF08478 POTRA domain, FtsQ-type SPy_1524 PF04101 Glycosyltransferase family 28 C-terminal domain SPy_1524 PF03033 Glycosyltransferase family 28 N-terminal domain SPy_1525 PF08245 Mur ligase middle domain SPy_1525 PF02875 Mur ligase family, glutamate ligase domain SPy_1527 PF03144 Elongation factor Tu domain 2 SPy_1527 PF14492 Elongation Factor G, domain II SPy_1527 PF00679 Elongation factor G C-terminus SPy_1527 PF00009 Elongation factor Tu GTP binding domain SPy_1528 PF00581 Rhodanese-like domain SPy_1529 PF00480 ROK family SPy_1531 PF00210 Ferritin-like domain SPy_1533 PF04055 Radical SAM superfamily SPy_1534 PF06265 Protein of unknown function (DUF1027) SPy_1535 PF00356 Bacterial regulatory proteins, lacI family SPy_1536 PF13180 PDZ domain SPy_1536 PF05362 Lon protease (S16) C-terminal proteolytic domain SPy_1537 PF01467 Cytidylyltransferase-like SPy_1539 PF03590 Aspartate-ammonia ligase SPy_1541 PF00696 Amino acid kinase family SPy_1542 PF01546 Peptidase family M20/M25/M40 SPy_1543 PF03606 C4-dicarboxylate anaerobic carrier SPy_1544 PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain SPy_1544 PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain SPy_1546 PF13673 Acetyltransferase (GNAT) domain SPy_1549 PF02863 Arginine repressor, C-terminal domain SPy_1549 PF01316 Arginine repressor, DNA binding domain SPy_1553 PF02743 Cache domain SPy_1553 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1553 PF00672 HAMP domain SPy_1553 PF06580 Histidine kinase SPy_1556 PF12833 Helix-turn-helix domain SPy_1556 PF00072 Response regulator receiver domain SPy_1557 PF01625 Peptide methionine sulfoxide reductase SPy_1557 PF01641 SelR domain SPy_1558 PF08534 Redoxin SPy_1559 PF02683 Cytochrome C biogenesis protein transmembrane region SPy_1561 PF09827 CRISPR associated protein Cas2 SPy_1562 PF01867 CRISPR associated protein Cas1 SPy_1568 PF00133 tRNA synthetases class I (I, L, M and V) SPy_1568 PF10458 Valyl tRNA synthetase tRNA binding arm SPy_1568 PF08264 Anticodon-binding domain of tRNA SPy_1574 PF13808 DDE_Tnp_1-associated SPy_1574 PF01609 Transposase DDE domain SPy_1576 PF00793 DAHP synthetase I family SPy_1576 PF01817 Chorismate mutase type II SPy_1577 PF01761 3-dehydroquinate synthase SPy_1582 PF13649 Methyltransferase domain SPy_1584 PF08501 Shikimate dehydrogenase substrate binding domain SPy_1584 PF18317 Shikimate 5'-dehydrogenase C-terminal domain SPy_1586 PF00703 Glycosyl hydrolases family 2 SPy_1586 PF16355 Domain of unknown function (DUF4982) SPy_1586 PF02836 Glycosyl hydrolases family 2, TIM barrel domain SPy_1586 PF02837 Glycosyl hydrolases family 2, sugar binding domain SPy_1586 PF18565 Glycoside hydrolase family 2 C-terminal domain 5 SPy_1587 PF00072 Response regulator receiver domain SPy_1587 PF12833 Helix-turn-helix domain SPy_1588 PF06580 Histidine kinase SPy_1588 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1588 PF00672 HAMP domain SPy_1588 PF02743 Cache domain SPy_1592 PF12010 Domain of unknown function (DUF3502) SPy_1593 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1595 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1596 PF00480 ROK family SPy_1599 PF00232 Glycosyl hydrolase family 1 SPy_1600 PF02838 Glycosyl hydrolase family 20, domain 2 SPy_1600 PF07555 beta-N-acetylglucosaminidase SPy_1602 PF00392 Bacterial regulatory proteins, gntR family SPy_1604 PF18438 Glycosyl hydrolases family 38 C-terminal domain 1 SPy_1604 PF01074 Glycosyl hydrolases family 38 N-terminal domain SPy_1604 PF07748 Glycosyl hydrolases family 38 C-terminal domain SPy_1604 PF17677 Glycosyl hydrolases family 38 C-terminal beta sandwich domain SPy_1604 PF09261 Alpha mannosidase middle domain SPy_1606 PF01938 TRAM domain SPy_1606 PF05958 tRNA (Uracil-5-)-methyltransferase SPy_1607 PF02631 RecX family SPy_1608 PF04167 Protein of unknown function (DUF402) SPy_1613 PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus SPy_1613 PF02482 Sigma 54 modulation protein / S30EA ribosomal protein SPy_1616 PF04851 Type III restriction enzyme, res subunit SPy_1616 PF00271 Helicase conserved C-terminal domain SPy_1617 PF09186 Domain of unknown function (DUF1949) SPy_1617 PF01205 Uncharacterized protein family UPF0029 SPy_1618 PF00291 Pyridoxal-phosphate dependent enzyme SPy_1619 PF00575 S1 RNA binding domain SPy_1620 PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SPy_1621 PF00072 Response regulator receiver domain SPy_1621 PF00196 Bacterial regulatory proteins, luxR family SPy_1622 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_1622 PF00672 HAMP domain SPy_1622 PF07730 Histidine kinase SPy_1625 PF03793 PASTA domain SPy_1625 PF00069 Protein kinase domain SPy_1627 PF01029 NusB family SPy_1627 PF01189 16S rRNA methyltransferase RsmB/F SPy_1628 PF02911 Formyl transferase, C-terminal domain SPy_1628 PF00551 Formyl transferase SPy_1629 PF17764 3′ DNA-binding domain (3′BD) SPy_1629 PF00271 Helicase conserved C-terminal domain SPy_1629 PF18319 PriA DNA helicase Cys-rich region (CRR) domain SPy_1629 PF04851 Type III restriction enzyme, res subunit SPy_1629 PF18074 Primosomal protein N C-terminal domain SPy_1630 PF01192 RNA polymerase Rpb6 SPy_1632 PF00625 Guanylate kinase SPy_1633 PF01966 HD domain SPy_1633 PF00013 KH domain SPy_1633 PF12072 Domain of unknown function (DUF3552) SPy_1634 PF03466 LysR substrate binding domain SPy_1634 PF00126 Bacterial regulatory helix-turn-helix protein, lysR family SPy_1637 PF00108 Thiolase, N-terminal domain SPy_1637 PF02803 Thiolase, C-terminal domain SPy_1638 PF01144 Coenzyme A transferase SPy_1639 PF01144 Coenzyme A transferase SPy_1642 PF02664 S-Ribosylhomocysteinase (LuxS) SPy_1643 PF18708 MapZ extracellular C-terminal domain 2 SPy_1643 PF18041 MapZ extracellular domain 1 SPy_1644 PF01170 Putative RNA methylase family UPF0020 SPy_1644 PF02926 THUMP domain SPy_1646 PF05103 DivIVA protein SPy_1647 PF06908 YspA SLOG family SPy_1648 PF03838 Recombination protein U SPy_1649 PF00912 Transglycosylase SPy_1649 PF00905 Penicillin binding protein transpeptidase domain SPy_1651 PF03051 Peptidase C1-like family SPy_1652 PF02540 NAD synthase SPy_1653 PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family SPy_1653 PF17767 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain SPy_1653 PF17956 Nicotinate phosphoribosyltransferase C-terminal domain SPy_1654 PF00324 Amino acid permease SPy_1657 PF00005 ABC transporter SPy_1658 PF00528 Binding-protein-dependent transport system inner membrane component SPy_1659 PF00271 Helicase conserved C-terminal domain SPy_1659 PF00270 DEAD/DEAH box helicase SPy_1662 PF00953 Glycosyl transferase family 4 SPy_1662 PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 SPy_1664 PF03793 PASTA domain SPy_1664 PF03717 Penicillin-binding Protein dimerisation domain SPy_1664 PF00905 Penicillin binding protein transpeptidase domain SPy_1666 PF01795 MraW methylase family SPy_1670 PF00171 Aldehyde dehydrogenase family SPy_1672 PF00696 Amino acid kinase family SPy_1674 PF00005 ABC transporter SPy_1676 PF02779 Transketolase, pyrimidine binding domain SPy_1676 PF02780 Transketolase, C-terminal domain SPy_1676 PF00456 Transketolase, thiamine diphosphate binding domain SPy_1678 PF00923 Transaldolase/Fructose-6-phosphate aldolase SPy_1681 PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain SPy_1681 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_1682 PF00230 Major intrinsic protein SPy_1683 PF01266 FAD dependent oxidoreductase SPy_1683 PF16901 C-terminal domain of alpha-glycerophosphate oxidase SPy_1684 PF02782 FGGY family of carbohydrate kinases, C-terminal domain SPy_1684 PF00370 FGGY family of carbohydrate kinases, N-terminal domain SPy_1686 PF03413 Peptidase propeptide and YPEB domain SPy_1687 PF05979 Bacterial protein of unknown function (DUF896) SPy_1688 PF02092 Glycyl-tRNA synthetase beta subunit SPy_1689 PF02091 Glycyl-tRNA synthetase alpha subunit SPy_1691 PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family SPy_1693 PF00248 Aldo/keto reductase family SPy_1694 PF01979 Amidohydrolase family SPy_1695 PF02690 Na+/Pi-cotransporter SPy_1698 PF02645 Uncharacterised protein, DegV family COG1307 SPy_1699 PF00440 Bacterial regulatory proteins, tetR family SPy_1701 PF03458 UPF0126 domain SPy_1704 PF01791 DeoC/LacD family aldolase SPy_1707 PF02502 Ribose/Galactose Isomerase SPy_1708 PF02502 Ribose/Galactose Isomerase SPy_1712 PF08220 DeoR-like helix-turn-helix domain SPy_1712 PF00455 DeoR C terminal sensor domain SPy_1715 PF00403 Heavy-metal-associated domain SPy_1717 PF03965 Penicillinase repressor SPy_1718 PF07859 alpha/beta hydrolase fold SPy_1719 PF02033 Ribosome-binding factor A SPy_1721 PF11987 Translation-initiation factor 2 SPy_1721 PF04760 Translation initiation factor IF-2, N-terminal region SPy_1721 PF00009 Elongation factor Tu GTP binding domain SPy_1722 PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family SPy_1723 PF04296 Protein of unknown function (DUF448) SPy_1724 PF13184 NusA-like KH domain SPy_1724 PF08529 NusA N-terminal domain SPy_1724 PF00575 S1 RNA binding domain SPy_1725 PF02576 RimP N-terminal domain SPy_1725 PF17384 RimP C-terminal SH3 domain SPy_1726 PF02390 Putative methyltransferase SPy_1728 PF05975 Bacterial ABC transporter protein EcsB SPy_1729 PF00005 ABC transporter SPy_1730 PF01230 HIT domain SPy_1733 PF03816 Cell envelope-related transcriptional attenuator domain SPy_1735 PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE SPy_1736 PF00860 Permease family SPy_1738 PF03830 PTS system sorbose subfamily IIB component SPy_1738 PF03610 PTS system fructose IIA component SPy_1739 PF03609 PTS system sorbose-specific iic component SPy_1740 PF03613 PTS system mannose/fructose/sorbose family IID component SPy_1742 PF02403 Seryl-tRNA synthetase N-terminal domain SPy_1742 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPy_1743 PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit SPy_1744 PF01039 Carboxyl transferase domain SPy_1744 PF17848 Acetyl-coA carboxylase zinc finger domain SPy_1745 PF02785 Biotin carboxylase C-terminal domain SPy_1745 PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain SPy_1745 PF00289 Biotin carboxylase, N-terminal domain SPy_1746 PF07977 FabA-like domain SPy_1747 PF00364 Biotin-requiring enzyme SPy_1748 PF02801 Beta-ketoacyl synthase, C-terminal domain SPy_1748 PF00109 Beta-ketoacyl synthase, N-terminal domain SPy_1750 PF00698 Acyl transferase domain SPy_1751 PF03060 Nitronate monooxygenase SPy_1753 PF00550 Phosphopantetheine attachment site SPy_1754 PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal SPy_1754 PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III SPy_1758 PF00378 Enoyl-CoA hydratase/isomerase SPy_1759 PF00226 DnaJ domain SPy_1759 PF01556 DnaJ C terminal domain SPy_1759 PF00684 DnaJ central domain SPy_1760 PF00012 Hsp70 protein SPy_1761 PF01025 GrpE SPy_1763 PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding SPy_1763 PF01628 HrcA protein C terminal domain SPy_1766 PF00300 Histidine phosphatase superfamily (branch 1) SPy_1768 PF04226 Transglycosylase associated protein SPy_1770 PF02637 GatB domain SPy_1770 PF02934 GatB/GatE catalytic domain SPy_1771 PF01425 Amidase SPy_1772 PF02686 Glu-tRNAGln amidotransferase C subunit SPy_1776 PF00857 Isochorismatase family SPy_1777 PF06018 CodY GAF-like domain SPy_1777 PF08222 CodY helix-turn-helix domain SPy_1779 PF00155 Aminotransferase class I and II SPy_1782 PF17763 Glutaminase/Asparaginase C-terminal domain SPy_1782 PF00710 Asparaginase, N-terminal SPy_1784 PF00005 ABC transporter SPy_1785 PF17191 RecG wedge domain SPy_1785 PF00271 Helicase conserved C-terminal domain SPy_1785 PF00270 DEAD/DEAH box helicase SPy_1787 PF00005 ABC transporter SPy_1790 PF00005 ABC transporter SPy_1790 PF00664 ABC transporter transmembrane region SPy_1791 PF00005 ABC transporter SPy_1791 PF00664 ABC transporter transmembrane region SPy_1793 PF00005 ABC transporter SPy_1794 PF01032 FecCD transport family SPy_1795 PF01497 Periplasmic binding protein SPy_1801 PF05257 CHAP domain SPy_1801 PF01476 LysM domain SPy_1802 PF01168 Alanine racemase, N-terminal domain SPy_1802 PF00842 Alanine racemase, C-terminal domain SPy_1804 PF01648 4'-phosphopantetheinyl transferase superfamily SPy_1805 PF07516 SecA Wing and Scaffold domain SPy_1805 PF07517 SecA DEAD-like domain SPy_1805 PF01043 SecA preprotein cross-linking domain SPy_1805 PF02810 SEC-C motif SPy_1807 PF01609 Transposase DDE domain SPy_1807 PF13808 DDE_Tnp_1-associated SPy_1810 PF01238 Phosphomannose isomerase type I SPy_1811 PF00480 ROK family SPy_1815 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPy_1815 PF02378 Phosphotransferase system, EIIC SPy_1815 PF00367 phosphotransferase system, EIIB SPy_1816 PF08244 Glycosyl hydrolases family 32 C terminal SPy_1816 PF00251 Glycosyl hydrolases family 32 N-terminal domain SPy_1817 PF00356 Bacterial regulatory proteins, lacI family SPy_1818 PF01029 NusB family SPy_1820 PF03780 Asp23 family, cell envelope-related function SPy_1821 PF01132 Elongation factor P (EF-P) OB domain SPy_1821 PF08207 Elongation factor P (EF-P) KOW-like domain SPy_1821 PF09285 Elongation factor P, C-terminal SPy_1823 PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region SPy_1824 PF01321 Creatinase/Prolidase N-terminal domain SPy_1824 PF00557 Metallopeptidase family M24 SPy_1825 PF17755 UvrA DNA-binding domain SPy_1825 PF17760 UvrA interaction domain SPy_1825 PF00005 ABC transporter SPy_1829 PF01084 Ribosomal protein S18 SPy_1830 PF00436 Single-strand binding protein family SPy_1831 PF01250 Ribosomal protein S6 SPy_1833 PF00730 HhH-GPD superfamily base excision DNA repair protein SPy_1833 PF14815 NUDIX domain SPy_1834 PF01381 Helix-turn-helix SPy_1835 PF00085 Thioredoxin SPy_1837 PF00488 MutS domain V SPy_1837 PF01713 Smr domain SPy_1841 PF11858 Domain of unknown function (DUF3378) SPy_1841 PF01351 Ribonuclease HII SPy_1842 PF10502 Signal peptidase, peptidase S26 SPy_1844 PF18335 ATP-dependent RecD-like DNA helicase SH3 domain SPy_1844 PF14490 Helix-hairpin-helix containing domain SPy_1844 PF13538 UvrD-like helicase C-terminal domain SPy_1846 PF00817 impB/mucB/samB family SPy_1846 PF11798 IMS family HHH motif SPy_1846 PF11799 impB/mucB/samB family C-terminal domain SPy_1849 PF01228 Glycine radical SPy_1849 PF02901 Pyruvate formate lyase-like SPy_1850 PF00144 Beta-lactamase SPy_1854 PF00230 Major intrinsic protein SPy_1856 PF07690 Major Facilitator Superfamily SPy_1857 PF13545 Crp-like helix-turn-helix domain SPy_1858 PF02129 X-Pro dipeptidyl-peptidase (S15 family) SPy_1858 PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal SPy_1858 PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain SPy_1862 PF02575 YbaB/EbfC DNA-binding family SPy_1863 PF07739 TipAS antibiotic-recognition domain SPy_1863 PF13411 MerR HTH family regulatory protein SPy_1865 PF04394 Protein of unknown function, DUF536 SPy_1865 PF08279 HTH domain SPy_1867 PF01791 DeoC/LacD family aldolase SPy_1868 PF07670 Nucleoside recognition SPy_1868 PF07662 Na+ dependent nucleoside transporter C-terminus SPy_1868 PF01773 Na+ dependent nucleoside transporter N-terminus SPy_1869 PF01048 Phosphorylase superfamily SPy_1871 PF00253 Ribosomal protein S14p/S29e SPy_1872 PF00814 Glycoprotease family SPy_1873 PF00583 Acetyltransferase (GNAT) family SPy_1874 PF00814 Glycoprotease family SPy_1875 PF07288 Protein of unknown function (DUF1447) SPy_1876 PF07521 Zn-dependent metallo-hydrolase RNA specificity domain SPy_1876 PF00753 Metallo-beta-lactamase superfamily SPy_1876 PF17770 Ribonuclease J C-terminal domain SPy_1877 PF00120 Glutamine synthetase, catalytic domain SPy_1877 PF03951 Glutamine synthetase, beta-Grasp domain SPy_1878 PF13411 MerR HTH family regulatory protein SPy_1881 PF00162 Phosphoglycerate kinase SPy_1882 PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) SPy_1885 PF02734 DAK2 domain SPy_1885 PF13684 Dihydroxyacetone kinase family SPy_1886 PF03780 Asp23 family, cell envelope-related function SPy_1888 PF00830 Ribosomal L28 family SPy_1889 PF01116 Fructose-bisphosphate aldolase class-II SPy_1894 PF00117 Glutamine amidotransferase class-I SPy_1894 PF06418 CTP synthase N-terminus SPy_1895 PF05066 HB1, ASXL, restriction endonuclease HTH domain SPy_1896 PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase SPy_1896 PF05698 Bacterial trigger factor protein (TF) C-terminus SPy_1896 PF05697 Bacterial trigger factor protein (TF) SPy_1897 PF00924 Mechanosensitive ion channel SPy_1898 PF04260 Protein of unknown function (DUF436) SPy_1899 PF07155 ECF-type riboflavin transporter, S component SPy_1900 PF08543 Phosphomethylpyrimidine kinase SPy_1901 PF01416 tRNA pseudouridine synthase SPy_1903 PF02595 Glycerate kinase family SPy_1904 PF18766 SWI2/SNF2 ATPase SPy_1904 PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) SPy_1904 PF12008 Type I restriction and modification enzyme - subunit R C terminal SPy_1906 PF12161 HsdM N-terminal domain SPy_1906 PF02384 N-6 DNA Methylase SPy_1908 PF00072 Response regulator receiver domain SPy_1908 PF00486 Transcriptional regulatory protein, C terminal SPy_1911 PF02687 FtsX-like permease family SPy_1912 PF00005 ABC transporter SPy_1913 PF00664 ABC transporter transmembrane region SPy_1913 PF00005 ABC transporter SPy_1915 PF04604 Type-A lantibiotic SPy_1916 PF00232 Glycosyl hydrolase family 1 SPy_1917 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_1917 PF02378 Phosphotransferase system, EIIC SPy_1918 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPy_1919 PF01791 DeoC/LacD family aldolase SPy_1921 PF00294 pfkB family carbohydrate kinase SPy_1922 PF02502 Ribose/Galactose Isomerase SPy_1923 PF02502 Ribose/Galactose Isomerase SPy_1924 PF08220 DeoR-like helix-turn-helix domain SPy_1924 PF00455 DeoR C terminal sensor domain SPy_1931 PF00380 Ribosomal protein S9/S16 SPy_1932 PF00572 Ribosomal protein L13 SPy_1934 PF01381 Helix-turn-helix SPy_1936 PF02645 Uncharacterised protein, DegV family COG1307 SPy_1938 PF08032 RNA 2'-O ribose methyltransferase substrate binding SPy_1938 PF00588 SpoU rRNA Methylase family SPy_1940 PF00636 Ribonuclease III domain SPy_1941 PF01406 tRNA synthetases class I (C) catalytic domain SPy_1941 PF09190 DALR domain SPy_1944 PF00132 Bacterial transferase hexapeptide (six repeats) SPy_1944 PF06426 Serine acetyltransferase, N-terminal SPy_1946 PF00013 KH domain SPy_1946 PF01138 3' exoribonuclease family, domain 1 SPy_1946 PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain SPy_1946 PF00575 S1 RNA binding domain SPy_1946 PF03725 3' exoribonuclease family, domain 2 SPy_1947 PF00923 Transaldolase/Fructose-6-phosphate aldolase SPy_1949 PF03611 PTS system sugar-specific permease component SPy_1950 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_1952 PF00874 PRD domain SPy_1952 PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 SPy_1952 PF08279 HTH domain SPy_1952 PF05043 Mga helix-turn-helix domain SPy_1952 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_1955 PF00312 Ribosomal protein S15 SPy_1958 PF01327 Polypeptide deformylase SPy_1959 PF03358 NADPH-dependent FMN reductase SPy_1960 PF01047 MarR family SPy_1961 PF11490 DNA polymerase III polC-type N-terminus II SPy_1961 PF14480 DNA polymerase III polC-type N-terminus I SPy_1961 PF00929 Exonuclease SPy_1961 PF02811 PHP domain SPy_1961 PF14579 Helix-hairpin-helix motif SPy_1961 PF07733 Bacterial DNA polymerase III alpha NTPase domain SPy_1961 PF17657 Bacterial DNA polymerase III alpha subunit finger domain SPy_1962 PF00587 tRNA synthetase class II core domain (G, H, P, S and T) SPy_1962 PF04073 Aminoacyl-tRNA editing domain SPy_1962 PF03129 Anticodon binding domain SPy_1963 PF13180 PDZ domain SPy_1963 PF02163 Peptidase family M50 SPy_1965 PF01255 Putative undecaprenyl diphosphate synthase SPy_1968 PF02699 Preprotein translocase subunit SPy_1972 PF17999 Pullulanase N1-terminal domain SPy_1972 PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) SPy_1972 PF00128 Alpha amylase, catalytic domain SPy_1973 PF00128 Alpha amylase, catalytic domain SPy_1976 PF00005 ABC transporter SPy_1976 PF17912 MalK OB fold domain SPy_1976 PF03459 TOBE domain SPy_1978 PF13556 PucR C-terminal helix-turn-helix domain SPy_1979 PF02821 Staphylokinase/Streptokinase family SPy_1980 PF02580 D-Tyr-tRNA(Tyr) deacylase SPy_1981 PF13291 ACT domain SPy_1981 PF04607 Region found in RelA / SpoT proteins SPy_1981 PF02824 TGS domain SPy_1983 PF02370 M protein repeat SPy_1983 PF00746 LPXTG cell wall anchor motif SPy_1984 PF07972 NrdI Flavodoxin like SPy_1985 PF03372 Endonuclease/Exonuclease/phosphatase family SPy_1986 PF02378 Phosphotransferase system, EIIC SPy_1986 PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 SPy_1986 PF00367 phosphotransferase system, EIIB SPy_1987 PF04452 RNA methyltransferase SPy_1990 PF00425 chorismate binding enzyme SPy_1990 PF04715 Anthranilate synthase component I, N terminal region SPy_1991 PF00117 Glutamine amidotransferase class-I SPy_1992 PF16193 AAA C-terminal domain SPy_1992 PF05496 Holliday junction DNA helicase RuvB P-loop domain SPy_1992 PF12002 MgsA AAA+ ATPase C terminal SPy_1998 PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain SPy_1998 PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain SPy_2000 PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle SPy_2001 PF00528 Binding-protein-dependent transport system inner membrane component SPy_2002 PF00528 Binding-protein-dependent transport system inner membrane component SPy_2003 PF00005 ABC transporter SPy_2003 PF12558 ATP-binding cassette cobalt transporter SPy_2004 PF00005 ABC transporter SPy_2005 PF05532 CsbD-like SPy_2007 PF01297 Zinc-uptake complex component A periplasmic SPy_2010 PF06280 Fn3-like domain SPy_2010 PF00082 Subtilase family SPy_2010 PF02225 PA domain SPy_2018 PF00746 LPXTG cell wall anchor motif SPy_2018 PF04650 YSIRK type signal peptide SPy_2019 PF08280 M protein trans-acting positive regulator (MGA) HTH domain SPy_2019 PF05043 Mga helix-turn-helix domain SPy_2019 PF08270 M protein trans-acting positive regulator (MGA) PRD domain SPy_2025 PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase SPy_2025 PF05257 CHAP domain SPy_2026 PF13493 Domain of unknown function (DUF4118) SPy_2026 PF02702 Osmosensitive K+ channel His kinase sensor domain SPy_2026 PF00512 His Kinase A (phospho-acceptor) domain SPy_2026 PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPy_2027 PF00486 Transcriptional regulatory protein, C terminal SPy_2027 PF00072 Response regulator receiver domain SPy_2029 PF12704 MacB-like periplasmic core domain SPy_2029 PF02687 FtsX-like permease family SPy_2031 PF00005 ABC transporter SPy_2037 PF13145 PPIC-type PPIASE domain SPy_2039 PF13734 Spi protease inhibitor SPy_2039 PF01640 Peptidase C10 family SPy_2045 PF04608 Phosphatidylglycerophosphatase A SPy_2047 PF00465 Iron-containing alcohol dehydrogenase SPy_2048 PF00923 Transaldolase/Fructose-6-phosphate aldolase SPy_2049 PF01228 Glycine radical SPy_2049 PF02901 Pyruvate formate lyase-like SPy_2050 PF02378 Phosphotransferase system, EIIC SPy_2051 PF02302 PTS system, Lactose/Cellobiose specific IIB subunit SPy_2052 PF02255 PTS system, Lactose/Cellobiose specific IIA subunit SPy_2053 PF04198 Putative sugar-binding domain SPy_2054 PF08220 DeoR-like helix-turn-helix domain SPy_2054 PF00455 DeoR C terminal sensor domain SPy_2055 PF04055 Radical SAM superfamily SPy_2059 PF00912 Transglycosylase SPy_2059 PF00905 Penicillin binding protein transpeptidase domain SPy_2063 PF01479 S4 domain SPy_2063 PF00849 RNA pseudouridylate synthase SPy_2066 PF03577 Peptidase family C69 SPy_2070 PF00118 TCP-1/cpn60 chaperonin family SPy_2072 PF00166 Chaperonin 10 Kd subunit SPy_2073 PF17871 AAA lid domain SPy_2073 PF10431 C-terminal, D2-small domain, of ClpB protein SPy_2073 PF07724 AAA domain (Cdc48 subfamily) SPy_2073 PF00004 ATPase family associated with various cellular activities (AAA) SPy_2073 PF02861 Clp amino terminal domain, pathogenicity island component SPy_2074 PF05848 CtsR N-terminal HTH domain SPy_2074 PF17727 CtsR C-terminal dimerization domain SPy_2077 PF00313 'Cold-shock' DNA-binding domain SPy_2079 PF00578 AhpC/TSA family SPy_2080 PF07992 Pyridine nucleotide-disulphide oxidoreductase SPy_2080 PF13192 Thioredoxin domain SPy_2081 PF01979 Amidohydrolase family SPy_2082 PF17391 Urocanase N-terminal domain SPy_2082 PF17392 Urocanase C-terminal domain SPy_2082 PF01175 Urocanase Rossmann-like domain SPy_2083 PF07837 Formiminotransferase domain, N-terminal subdomain SPy_2083 PF02971 Formiminotransferase domain SPy_2084 PF04961 Formiminotransferase-cyclodeaminase SPy_2085 PF01268 Formate--tetrahydrofolate ligase SPy_2088 PF13520 Amino acid permease SPy_2089 PF00221 Aromatic amino acid lyase SPy_2090 PF00491 Arginase family SPy_2092 PF00318 Ribosomal protein S2 SPy_2093 PF00889 Elongation factor TS SPy_2095 PF01431 Peptidase family M13 SPy_2095 PF05649 Peptidase family M13 SPy_2096 PF16657 Maltogenic Amylase, C-terminal domain SPy_2096 PF00128 Alpha amylase, catalytic domain SPy_2097 PF00367 phosphotransferase system, EIIB SPy_2097 PF02378 Phosphotransferase system, EIIC SPy_2099 PF00392 Bacterial regulatory proteins, gntR family SPy_2099 PF07702 UTRA domain SPy_2103 PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily SPy_2104 PF03883 Peroxide stress protein YaaA SPy_2107 PF01408 Oxidoreductase family, NAD-binding Rossmann fold SPy_2110 PF03477 ATP cone domain SPy_2110 PF13597 Anaerobic ribonucleoside-triphosphate reductase SPy_2112 PF06949 Protein of unknown function (DUF1292) SPy_2113 PF03652 Holliday junction resolvase SPy_2114 PF06135 IreB regulatory phosphoprotein SPy_2115 PF03960 ArsC family SPy_2116 PF00154 recA bacterial DNA recombination protein SPy_2117 PF00994 Probable molybdopterin binding domain SPy_2117 PF18146 Damage-inducible protein CinA KH domain SPy_2117 PF02464 Competence-damaged protein SPy_2118 PF00958 GMP synthase C terminal domain SPy_2118 PF00117 Glutamine amidotransferase class-I SPy_2118 PF03352 Methyladenine glycosylase SPy_2118 PF13302 Acetyltransferase (GNAT) domain SPy_2118 PF13673 Acetyltransferase (GNAT) domain SPy_2119 PF07499 RuvA, C-terminal domain SPy_2119 PF01330 RuvA N terminal domain SPy_2120 PF07690 Major Facilitator Superfamily SPy_2121 PF01119 DNA mismatch repair protein, C-terminal domain SPy_2121 PF08676 MutL C terminal dimerisation domain SPy_2148 PF05188 MutS domain II SPy_2148 PF05192 MutS domain III SPy_2148 PF05190 MutS family domain IV SPy_2148 PF00488 MutS domain V SPy_2148 PF01624 MutS domain I SPy_2150 PF02863 Arginine repressor, C-terminal domain SPy_2150 PF01316 Arginine repressor, DNA binding domain SPy_2151 PF00750 tRNA synthetases class I (R) SPy_2151 PF05746 DALR anticodon binding domain SPy_2151 PF03485 Arginyl tRNA synthetase N terminal domain SPy_2153 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPy_2153 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPy_2154 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPy_2154 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPy_2155 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPy_2155 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPy_2156 PF01336 OB-fold nucleic acid binding domain SPy_2156 PF00152 tRNA synthetases class II (D, K and N) SPy_2156 PF02938 GAD domain SPy_2157 PF13393 Histidyl-tRNA synthetase SPy_2157 PF03129 Anticodon binding domain SPy_2159 PF01783 Ribosomal L32p protein family SPy_2160 PF00471 Ribosomal protein L33 SPy_2163 PF01022 Bacterial regulatory protein, arsR family SPy_2170 PF00293 NUDIX domain SPy_2172 PF03551 Transcriptional regulator PadR-like family SPy_2178 PF00163 Ribosomal protein S4/S9 N-terminal domain SPy_2178 PF01479 S4 domain SPy_2180 PF01609 Transposase DDE domain SPy_2180 PF13808 DDE_Tnp_1-associated SPy_2182 PF00772 DnaB-like helicase N terminal domain SPy_2182 PF03796 DnaB-like helicase C terminal domain SPy_2183 PF03948 Ribosomal protein L9, C-terminal domain SPy_2183 PF01281 Ribosomal protein L9, N-terminal domain SPy_2184 PF01368 DHH family SPy_2184 PF02272 DHHA1 domain SPy_2185 PF13932 GidA associated domain SPy_2185 PF01134 Glucose inhibited division protein A SPy_2189 PF03315 Serine dehydratase beta chain SPy_2189 PF01842 ACT domain SPy_2190 PF03313 Serine dehydratase alpha chain SPy_2191 PF06737 Transglycosylase-like domain SPy_2193 PF02361 Cobalt transport protein SPy_2194 PF00005 ABC transporter SPy_2195 PF00005 ABC transporter SPy_2196 PF01066 CDP-alcohol phosphatidyltransferase SPy_2198 PF05193 Peptidase M16 inactive domain SPy_2198 PF00675 Insulinase (Peptidase family M16) SPy_2200 PF00535 Glycosyl transferase family 2 SPy_2201 PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain SPy_2201 PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain SPy_2201 PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SPy_2202 PF00483 Nucleotidyl transferase SPy_2204 PF02463 RecF/RecN/SMC N terminal domain SPy_2205 PF06800 Sugar transport protein SPy_2206 PF00478 IMP dehydrogenase / GMP reductase domain SPy_2206 PF00571 CBS domain SPy_2207 PF00579 tRNA synthetases class I (W and Y) SPy_2209 PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 SPy_2209 PF10035 Uncharacterized protein conserved in bacteria (DUF2179) SPy_2210 PF00005 ABC transporter SPy_2210 PF12848 ABC transporter SPy_2215 PF02590 Predicted SPOUT methyltransferase SPy_2216 PF13180 PDZ domain SPy_2217 PF02195 ParB-like nuclease domain SPy_2217 PF17762 HTH domain found in ParB protein