locus_tag	old_locus_tag	gene	Name	start	end	strand	product	note	type	ID	NCBI
SPy_0002	SPy0002	dnaA	dnaA	232	1587	+	Chromosomal initiator protein	Best Blastp hit %3D gb|AAF71535.1|AF255728_1 (AF255728) chromosomal initiator protein DnaA [Streptococcus pyogenes]	gene	gene0	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0002
SPy_0003	SPy0003	dnaN	dnaN	1742	2878	+	beta subunit of DNA polymerase III	Best Blastp hit %3D sp|O06672|DP3B_STRPN DNA POLYMERASE III%2C BETA CHAIN >gi|2109446|gb|AAC45337.1| (AF000658) beta subunit of DNA polymerase III [Streptococcus pneumoniae]	gene	gene1	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0003
SPy_0004	SPy0004		SPy_0004	2953	3150	+	hypothetical protein	Best Blastp hit %3D gb|AAC45338.1| (AF000658) ORFX [Streptococcus pneumoniae]	gene	gene2	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0004
SPy_0006	SPy0006		SPy_0006	3480	4595	+	putative GTP-binding protein	Best Blastp hit %3D dbj|BAB07770.1| (AP001520) GTP-binding protein [Bacillus halodurans]	gene	gene3	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0006
SPy_0007	SPy0007	pth	pth	4665	5234	+	putative peptidyl-tRNA hydrolase	Best Blastp hit %3D dbj|BAB03787.1| (AP001507) stage V sporulation protein C (peptidyl-tRNA hydrolase) [Bacillus halodurans]	gene	gene4	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0007
SPy_0008	SPy0008	trcF	trcF	5237	8740	+	putative transcription-repair coupling factor	Best Blastp hit %3D gb|AAD03810.1| (AF054624) transcription-repair coupling factor [Lactobacillus sakei]	gene	gene5	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0008
SPy_0009	SPy0009		SPy_0009	8878	9174	+	hypothetical protein	Best Blastp hit %3D sp|P37557|YABO_BACSU HYPOTHETICAL 9.7 KDA PROTEIN IN MFD-DIVIC INTERGENIC REGION >gi|2127042|pir||S66089 conserved hypothetical protein yabO - Bacillus subtilis >gi|467448|dbj|BAA05294.1| (D26185) unknown [Bacillus subtilis] >gi|2632326|emb|CAB11835.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene6	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0009
SPy_0010	SPy0010	divIC	divIC	9161	9532	+	putative cell division protein (DivIC)	Best Blastp hit %3D gb|AAC98903.1| (AF023181) DivIC homolog [Listeria monocytogenes]	gene	gene7	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0010
SPy_0012	SPy0012		SPy_0012	9667	10953	+	hypothetical protein	Best Blastp hit %3D gi|4758794 nebulin [Homo sapiens] >gi|1082786|pir||S55024 nebulin%2C skeletal muscle - human >gi|806562|emb|CAA58788.1| (X83957) nebulin [Homo sapiens]	gene	gene8	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0012
SPy_0013	SPy0013		SPy_0013	10950	12236	+	putative cell-cycle protein	Best Blastp hit %3D pir||S66097 cell-cycle protein homolog yacA - Bacillus subtilis >gi|467456|dbj|BAA05302.1| (D26185) unknown [Bacillus subtilis]	gene	gene9	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0013
SPy_0015	SPy0015	ftsH	ftsH	12805	14784	+	putative cell division protein	Best Blastp hit %3D gb|AAC16243.2| (AF061748) cell division protein FtsH [Streptococcus pneumoniae]	gene	gene10	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0015
SPy_0016	SPy0016		SPy_0016	15109	16500	+	putative amino acid permease	Best Blastp hit %3D pir||D69814 metabolite transporter homolog yfnA - Bacillus subtilis >gi|2633047|emb|CAB12553.1| (Z99107) similar to metabolite transporter [Bacillus subtilis] >gi|2633058|emb|CAB12563.1| (Z99108) similar to metabolite transporter [Bacillus subtilis]	gene	gene11	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0016
SPy_0019	SPy0019		SPy_0019	30545	31741	+	putative secreted protein	Best Blastp hit %3D gb|AAD00288.1| (U78607) putative secreted protein [Streptococcus mutans]	gene	gene37	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0019
SPy_0020	SPy0020	prsA.2	prsA.2	31994	32956	+	putative ribose-phosphate pyrophosphokinase	Best Blastp hit %3D gb|AAA62181.1| (M92842) prs [Listeria monocytogenes]	gene	gene38	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0020
SPy_0021	SPy0021		SPy_0021	33142	33897	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05088.1| (AP001511) unknown conserved protein [Bacillus halodurans]	gene	gene39	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0021
SPy_0022	SPy0022	plsX	plsX	34000	35007	+	putative fatty acid/phospholipid synthesis protein	Best Blastp hit %3D sp|P71018|PLSX_BACSU FATTY ACID/PHOSPHOLIPID SYNTHESIS PROTEIN PLSX >gi|7441727|pir||H69679 involved in fatty acid/phospholipid synthesis plsX - Bacillus subtilis >gi|2337818|emb|CAA74248.1| (Y13937) putative PlsX protein [Bacillus subtilis] >gi|2633961|emb|CAB13462.1| (Z99112) alternate gene name: ylpD [Bacillus subtilis]	gene	gene40	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0022
SPy_0023	SPy0023	acpP.2	acpP.2	35000	35242	+	putative acyl carrier protein	Best Blastp hit %3D gb|AAG22707.1| (AF276618) acyl carrier protein%3B AcpP%3B ACP [Streptococcus pneumoniae]	gene	gene41	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0023
SPy_0024	SPy0024	purC	purC	35363	36097	+	putative phosphoribosylaminoimidazole - succinocarboxamide synthase (SAICAR synthetase)	Best Blastp hit %3D sp|Q07296|PUR7_STRPN PHOSPHORIBOSYLAMINOIMIDAZOLE-SUCCINOCARBOXAMIDE SYNTHASE (SAICAR SYNTHETASE) >gi|625868|pir||A36941 phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) - Streptococcus pneumoniae >gi|295192|gb|AAA03540.1| (L15190) SAICAR synthetase [Streptococcus pneumoniae] >gi|663281|gb|AAA69512.1| (M36180) SAICAR synthetase [Streptococcus pneumoniae]	gene	gene42	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0024
SPy_0025	SPy0025		SPy_0025	36173	39946	+	putative phosphoribosylformylglycinamidine synthase II	Best Blastp hit %3D emb|CAC12194.1| (AL445066) phosphoribosylformylglycinamidine synthase related protein [Thermoplasma acidophilum]	gene	gene43	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0025
SPy_0026	SPy0026	purF	purF	40107	41561	+	putative phosphoribosylpyrophosphate amidotransferase	Best Blastp hit %3D pir||T51702 amidophosphoribosyltransferase (EC 2.4.2.14) [imported] - Lactococcus lactis >gi|4097534|gb|AAD12627.1| (U64311) phosphoribosylpyrophosphate amidotransferase [Lactococcus lactis]	gene	gene44	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0026
SPy_0027	SPy0027	purM	purM	41589	42611	+	putative phosphoribosylformylglycinamide cyclo-ligase	Best Blastp hit %3D gb|AAC16901.1| (AF016634) phosphoribosylformylglycinamide cyclo-ligase [Lactococcus lactis subsp. cremoris]	gene	gene45	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0027
SPy_0028	SPy0028	purN	purN	42779	43333	+	Phosphoribosylglycinamide formyltransferase	Best Blastp hit %3D gb|AAF08602.1|U70775_1 (U70775) phosphoribosylglycinamide formyltransferase homolog [Streptococcus pyogenes]	gene	gene46	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0028
SPy_0031	SPy0031		SPy_0031	45122	46246	-	putative choline binding protein	Best Blastp hit %3D gb|AAF87768.1|AF278686_1 (AF278686) choline binding protein D%3B CbpD [Streptococcus pneumoniae]	gene	gene47	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0031
SPy_0032	SPy0032	purD	purD	46499	47764	+	phosphoribosylamine-glycine ligase	Best Blastp hit %3D sp|Q9ZF44|PUR2_LACLA PHOSPHORIBOSYLAMINE-GLYCINE LIGASE (GARS) (GLYCINAMIDE RIBONUCLEOTIDE SYNTHETASE) (PHOSPHORIBOSYLGLYCINAMIDE SYNTHETASE) >gi|3892883|emb|CAA04374.1| (AJ000883) purD [Lactococcus lactis]	gene	gene48	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0032
SPy_0033	SPy0033	purE	purE	48042	48533	+	putative phosphoribosylaminoimidazole carboxylase I	Best Blastp hit %3D emb|CAA04375.1| (AJ000883) purE [Lactococcus lactis]	gene	gene49	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0033
SPy_0034	SPy0034	purK	purK	48484	49593	+	phosphoribosylaminoimidazole carboxylase II	Best Blastp hit %3D emb|CAA04376.1| (AJ000883) purK [Lactococcus lactis]	gene	gene50	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0034
SPy_0035	SPy0035	abiR	abiR	49620	51263	+	possible abortive infection phage resistance protein	Best Blastp hit %3D gb|AAG17058.1|AF188839_1 (AF188839) abortive infection phage resistance protein abiR [Lactococcus lactis subsp. lactis]	gene	gene51	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0035
SPy_0036	SPy0036	purB	purB	51281	52573	+	adenylosuccinate lyase	Best Blastp hit %3D dbj|BAB04344.1| (AP001509) adenylosuccinate lyase [Bacillus halodurans]	gene	gene52	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0036
SPy_0037	SPy0037		SPy_0037	52705	53616	+	hypothetical protein	Best Blastp hit %3D pir||I40868 hypothetical protein 3 nanH region - Clostridium perfringens >gi|853809|emb|CAA60798.1| (X87369) ORF3 [Clostridium perfringens]	gene	gene53	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0037
SPy_0038	SPy0038	ruvB	ruvB	53842	54840	+	putative Holliday junction DNA helicase%2C subunit B	Best Blastp hit %3D sp|O32055|RUVB_BACSU HOLLIDAY JUNCTION DNA HELICASE RUVB >gi|6977806|emb|CAB75331.1| (Y15896) RuvB protein [Bacillus subtilis]	gene	gene54	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0038
SPy_0039	SPy0039		SPy_0039	54978	55415	+	putative protein-tyrosine phosphatase	Best Blastp hit %3D pir||E69808 protein-tyrosine phosphatase homolog yfkJ - Bacillus subtilis >gi|2626822|dbj|BAA23400.1| (D83967) YfkJ [Bacillus subtilis] >gi|2633112|emb|CAB12617.1| (Z99108) similar to protein-tyrosine phosphatase [Bacillus subtilis]	gene	gene55	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0039
SPy_0040	SPy0040		SPy_0040	55438	55839	+	hypothetical protein	Best Blastp hit %3D pir||S74454 hypothetical protein slr1485 - Synechocystis sp. (strain PCC 6803) >gi|1651678|dbj|BAA16606.1| (D90899) hypothetical protein [Synechocystis sp.]	gene	gene56	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0040
SPy_0041	SPy0041		SPy_0041	55836	57611	+	putative acyltransferase	Best Blastp hit %3D pir||T18748 hypothetical protein B0399.2 - Caenorhabditis elegans >gi|3947538|emb|CAB03808.1| (Z81455) contains similarity to Pfam domain: PF01757 (Domain of unknown function)%2C Score%3D520.1%2C E-value%3D5.2e-153%2C N%3D1 [Caenorhabditis elegans] >gi|3947633|emb|CAA21519.1| (AL032623) contains similarity to Pfam domain: PF01757 (Domain of unknown function)%2C Score%3D520.1%2C E-value%3D5.2e-153%2C N%3D1 [Caenorhabditis elegans]	gene	gene57	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0041
SPy_0044	SPy0044	adhA	adhA	60814	61830	+	putative alcohol dehydrogenase I	Best Blastp hit %3D pir||H81186 alcohol dehydrogenase%2C propanol-preferring NMB0546 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7225772|gb|AAF40975.1| (AE002410) alcohol dehydrogenase%2C propanol-preferring [Neisseria meningitidis MC58]	gene	gene58	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0044
SPy_0045	SPy0045		SPy_0045	62218	63510	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06655.1| (AP001517) unknown conserved protein [Bacillus halodurans]	gene	gene59	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0045
SPy_0047	SPy0047	rpsJ	rpsJ	63711	64019	+	30S ribosomal protein S10	Best Blastp hit %3D sp|P48853|RS10_STRMU 30S RIBOSOMAL PROTEIN S10 >gi|467321|gb|AAB46363.1| (L29637) S10 ribosomal protein [Streptococcus mutans]	gene	gene60	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0047
SPy_0049	SPy0049	rplC	rplC	64267	64893	+	50S ribosomal protein L3	Best Blastp hit %3D sp|P42920|RL3_BACSU 50S RIBOSOMAL PROTEIN L3 (BL3) >gi|7440603|pir||G69694 ribosomal protein L3 (BL3) rplC - Bacillus subtilis >gi|1165303|gb|AAC45956.1| (U43929) L3 [Bacillus subtilis] >gi|2632383|emb|CAB11892.1| (Z99104) ribosomal protein L3 (BL3) [Bacillus subtilis]	gene	gene61	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0049
SPy_0050	SPy0050	rplD	rplD	64917	65540	+	50S ribosomal protein L4	Best Blastp hit %3D sp|P42921|RL4_BACSU 50S RIBOSOMAL PROTEIN L4 >gi|7440640|pir||H69694 ribosomal protein L4 rplD - Bacillus subtilis >gi|786154|dbj|BAA08832.1| (D50302) Ribosomal Protein L4 [Bacillus subtilis] >gi|1165304|gb|AAC45957.1| (U43929) L4 [Bacillus subtilis] >gi|2632384|emb|CAB11893.1| (Z99104) ribosomal protein L4 [Bacillus subtilis]	gene	gene62	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0050
SPy_0051	SPy0051	rplW	rplW	65540	65836	+	50S ribosomal protein L23	Best Blastp hit %3D sp|Q9Z9L2|RL23_BACHD 50S RIBOSOMAL PROTEIN L23 >gi|11276846|pir||T44385 ribosomal protein L23 [imported] - Bacillus halodurans >gi|4512406|dbj|BAA75273.1| (AB017508) rplW homologue (identity of 71%25 to B. subtilis) [Bacillus halodurans] >gi|10172748|dbj|BAB03855.1| (AP001507) ribosomal protein L23 [Bacillus halodurans]	gene	gene63	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0051
SPy_0052	SPy0052	rplB	rplB	65854	66687	+	50S ribosomal protein L2	Best Blastp hit %3D sp|P04257|RL2_BACST 50S RIBOSOMAL PROTEIN L2	gene	gene64	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0052
SPy_0053	SPy0053	rpsS	rpsS	66826	67104	+	30S ribosomal protein S19	Best Blastp hit %3D sp|Q9WW12|RS19_STRPN 30S RIBOSOMAL PROTEIN S19 >gi|4927744|gb|AAD33260.1|AF126059_1 (AF126059) RpS19 [Streptococcus pneumoniae] >gi|4927753|gb|AAD33269.1| (AF126060) RpS19 [Streptococcus pneumoniae] >gi|4927762|gb|AAD33278.1| (AF126061) RpS19 [Streptococcus pneumoniae]	gene	gene65	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0053
SPy_0055	SPy0055	rplV	rplV	67120	67464	+	50S ribosomal protein L22	Best Blastp hit %3D sp|Q9WVU5|RL22_STRPN 50S RIBOSOMAL PROTEIN L22 >gi|4927745|gb|AAD33261.1|AF126059_2 (AF126059) RpL22 [Streptococcus pneumoniae] >gi|4927754|gb|AAD33270.1| (AF126060) RpL22 [Streptococcus pneumoniae] >gi|4927763|gb|AAD33279.1| (AF126061) RpL22 [Streptococcus pneumoniae]	gene	gene66	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0055
SPy_0056	SPy0056	rpsC	rpsC	67477	68130	+	30S ribosomal protein S3	Best Blastp hit %3D sp|Q9WW37|RS3_STRPN 30S RIBOSOMAL PROTEIN S3 >gi|4927746|gb|AAD33262.1|AF126059_3 (AF126059) RpS3 [Streptococcus pneumoniae] >gi|4927755|gb|AAD33271.1| (AF126060) RpS3 [Streptococcus pneumoniae] >gi|4927764|gb|AAD33280.1| (AF126061) RpS3 [Streptococcus pneumoniae]	gene	gene67	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0056
SPy_0057	SPy0057	rplP	rplP	68134	68547	+	50S ribosomal protein L16	Best Blastp hit %3D sp|Q9X5K1|RL16_STRPN 50S RIBOSOMAL PROTEIN L16 >gi|4927747|gb|AAD33263.1|AF126059_4 (AF126059) RpL16 [Streptococcus pneumoniae]	gene	gene68	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0057
SPy_0059	SPy0059	rpmC	rpmC	68557	68763	+	50S ribosomal protein L29	Best Blastp hit %3D sp|Q9WVW8|RL29_STRPN 50S RIBOSOMAL PROTEIN L29 >gi|4927748|gb|AAD33264.1|AF126059_5 (AF126059) RpL29 [Streptococcus pneumoniae] >gi|4927757|gb|AAD33273.1| (AF126060) RpL29 [Streptococcus pneumoniae] >gi|4927766|gb|AAD33282.1| (AF126061) RpL29 [Streptococcus pneumoniae]	gene	gene69	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0059
SPy_0060	SPy0060	rpsQ	rpsQ	68789	69049	+	30S ribosomal protein S17	Best Blastp hit %3D sp|Q9WW03|RS17_STRPN 30S RIBOSOMAL PROTEIN S17 >gi|4927749|gb|AAD33265.1|AF126059_6 (AF126059) RpS17 [Streptococcus pneumoniae] >gi|4927758|gb|AAD33274.1| (AF126060) RpS17 [Streptococcus pneumoniae] >gi|4927767|gb|AAD33283.1| (AF126061) RpS17 [Streptococcus pneumoniae]	gene	gene70	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0060
SPy_0061	SPy0061		SPy_0061	69074	69442	+	50S ribosomal protein L14	Best Blastp hit %3D sp|Q9WVZ2|RL14_STRPN 50S RIBOSOMAL PROTEIN L14 >gi|4927750|gb|AAD33266.1|AF126059_7 (AF126059) RpL14 [Streptococcus pneumoniae] >gi|4927759|gb|AAD33275.1| (AF126060) RpL14 [Streptococcus pneumoniae] >gi|4927768|gb|AAD33284.1| (AF126061) RpL14 [Streptococcus pneumoniae]	gene	gene71	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0061
SPy_0062	SPy0062	rplX	rplX	69521	69826	+	50S ribosomal protein L24	Best Blastp hit %3D sp|Q9WVW6|RL24_STRPN 50S RIBOSOMAL PROTEIN L24 >gi|4927751|gb|AAD33267.1|AF126059_8 (AF126059) RpL24 [Streptococcus pneumoniae] >gi|4927760|gb|AAD33276.1| (AF126060) RpL24 [Streptococcus pneumoniae] >gi|4927769|gb|AAD33285.1| (AF126061) RpL24 [Streptococcus pneumoniae]	gene	gene72	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0062
SPy_0063	SPy0063	rplE	rplE	69850	70392	+	50S ribosomal protein L5	Best Blastp hit %3D sp|Q9Z9K2|RL5_BACHD 50S RIBOSOMAL PROTEIN L5 >gi|11276701|pir||T44395 ribosomal protein L5 [imported] - Bacillus halodurans >gi|4512416|dbj|BAA75283.1| (AB017508) rplE homologue (identity of 86%25 to B. subtilis) [Bacillus halodurans] >gi|10172758|dbj|BAB03865.1| (AP001507) ribosomal protein L5 (BL6) [Bacillus halodurans]	gene	gene73	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0063
SPy_0064	SPy0064	rpsN	rpsN	70408	70593	+	30S ribosomal protein S14	Best Blastp hit %3D pir||S48688 ribosomal protein S14 - Bacillus stearothermophilus >gi|633867|gb|AAB31802.1| 30S ribosomal protein subunit S14 [Bacillus stearothermophilus%2C 799%2C Peptide%2C 60 aa]	gene	gene74	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0064
SPy_0065	SPy0065	rpsH	rpsH	70744	71142	+	30S ribosomal protein S8	Best Blastp hit %3D sp|P12879|RS8_BACSU 30S RIBOSOMAL PROTEIN S8 (BS8) >gi|1044978|gb|AAB06813.1| (L47971) ribosomal protein S8 [Bacillus subtilis]	gene	gene75	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0065
SPy_0066	SPy0066	rplF	rplF	71345	71881	+	50S ribosomal protein L6	Best Blastp hit %3D sp|P02391|RL6_BACST 50S RIBOSOMAL PROTEIN L6 (BL10)	gene	gene76	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0066
SPy_0067	SPy0067	rplR	rplR	71986	72342	+	50S ribosomal protein L18	Best Blastp hit %3D sp|P46899|RL18_BACSU 50S RIBOSOMAL PROTEIN L18 >gi|1044980|gb|AAB06815.1| (L47971) ribosomal protein L18 [Bacillus subtilis]	gene	gene77	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0067
SPy_0069	SPy0069	rpsE	rpsE	72361	72855	+	30S ribosomal protein S5	Best Blastp hit %3D sp|P02357|RS5_BACST 30S RIBOSOMAL PROTEIN S5 (BS5) >gi|70883|pir||R3BS5F ribosomal protein S5 - Bacillus stearothermophilus >gi|143417|gb|AAA22699.1| (M57621) ribosomal protein S5 [Bacillus stearothermophilus]	gene	gene78	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0069
SPy_0071	SPy0071	rpmD	rpmD	72870	73052	+	50S ribosomal protein L30	Best Blastp hit %3D sp|O06444|RL30_STAAU 50S RIBOSOMAL PROTEIN L30 >gi|2078380|gb|AAB54020.1| (U96620) ribosomal protein L30 [Staphylococcus aureus]	gene	gene79	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0071
SPy_0072	SPy0072	rplO	rplO	73266	73706	+	50S ribosomal protein L15	Best Blastp hit %3D sp|O06445|RL15_STAAU 50S RIBOSOMAL PROTEIN L15 >gi|2078381|gb|AAB54021.1| (U96620) ribosomal protein L15 [Staphylococcus aureus]	gene	gene80	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0072
SPy_0073	SPy0073	secY	secY	73723	75027	+	putative preprotein translocase	Best Blastp hit %3D sp|P27148|SECY_LACLA PREPROTEIN TRANSLOCASE SECY SUBUNIT >gi|97983|pir||S17985 preprotein translocase secY - Lactococcus lactis subsp. lactis >gi|44073|emb|CAA41939.1| (X59250) SecY protein [Lactococcus lactis] >gi|228026|prf||1715214A secY gene [Lactococcus lactis]	gene	gene81	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0073
SPy_0074	SPy0074	adk	adk	75177	75815	+	adenylate kinase	Best Blastp hit %3D sp|P27143|KAD_LACLA ADENYLATE KINASE (ATP-AMP TRANSPHOSPHORYLASE) >gi|97972|pir||S17987 adenylate kinase (EC 2.7.4.3) - Lactococcus lactis subsp. lactis >gi|322101|pir||B44812 adenylate kinase (EC 2.7.4.3) - Lactococcus lactis >gi|44074|emb|CAA41940.1| (X59250) adenylate kinase [Lactococcus lactis]	gene	gene82	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0074
SPy_0075	SPy0075	infA	infA	75933	76151	+	putative translation initiation factor IF-1	Best Blastp hit %3D pir||S17988 translation initiation factor IF-1 - Lactococcus lactis subsp. lactis	gene	gene83	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0075
SPy_0076	SPy0076	rpmJ	rpmJ	76177	76293	+	50S ribosomal protein B	Best Blastp hit %3D sp|P27146|RL36_LACLA 50S RIBOSOMAL PROTEIN L36 (RIBOSOMAL PROTEIN B) >gi|97981|pir||S17989 ribosomal protein L36 - Lactococcus lactis subsp. lactis >gi|322111|pir||D44812 ribosomal protein B - Lactococcus lactis >gi|44076|emb|CAA41942.1| (X59250) ribosomal protein B [Lactococcus lactis]	gene	gene84	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0076
SPy_0077	SPy0077	rpsM	rpsM	76311	76676	+	30S ribosomal protein S13	Best Blastp hit %3D sp|P20282|RS13_BACSU 30S RIBOSOMAL PROTEIN S13 (BS14) >gi|1044989|gb|AAB06824.1| (L47971) ribosomal protein S13 [Bacillus subtilis]	gene	gene85	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0077
SPy_0078	SPy0078	rpsK	rpsK	76694	77077	+	30S ribosomal protein S11	Best Blastp hit %3D sp|P04969|RS11_BACSU 30S RIBOSOMAL PROTEIN S11 (BS11) >gi|70938|pir||R3BSS1 ribosomal protein S11 - Bacillus subtilis >gi|142462|gb|AAA22216.1| (M26414) ribosomal protein S11 [Bacillus subtilis] >gi|143451|gb|AAA22707.1| (M13957) ribosomal protein S11 [Bacillus subtilis] >gi|1044990|gb|AAB06825.1| (L47971) ribosomal protein S11 [Bacillus subtilis] >gi|2632409|emb|CAB11918.1| (Z99104) ribosomal protein S11 (BS11) [Bacillus subtilis]	gene	gene86	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0078
SPy_0080	SPy0080	rpoA	rpoA	77123	78061	+	DNA-directed RNA polymerase alpha subunit	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|O50634|RPOA_BACHD DNA-DIRECTED RNA POLYMERASE ALPHA CHAIN (TRANSCRIPTASE ALPHA CHAIN) (RNA POLYMERASE ALPHA SUBUNIT) >gi|11261105|pir||T44410 DNA-directed RNA polymerase (EC 2.7.7.6) alpha chain rpoA [imported] - Bacillus halodurans >gi|2760185|dbj|BAA24194.1| (AB010082) RNA polymerase alpha subunit [Bacillus halodurans] >gi|4512431|dbj|BAA75298.1| (AB017508) rpoA homologue (identity of 85%25 to B. subtilis) [Bacillus halodurans] >gi|10172774|dbj|BAB03881.1| (AP001507) DNA-directed RNA polymerase alpha subunit [Bacillus halodurans]	gene	gene87	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0080
SPy_0084	SPy0084		SPy_0084	85707	85892	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene103	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0084
SPy_0088	SPy0088		SPy_0088	86530	87100	+		isopentenyl monophosphate kinase%3B Multiple mutation within this gene have been confirmed by sequence analysis	gene	gene104	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0088
SPy_0092	SPy0092	adcR	adcR	87213	87656	+	putative repressor protein	Best Blastp hit %3D emb|CAA96184.1| (Z71552) AdcR protein [Streptococcus pneumoniae]	gene	gene105	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0092
SPy_0093	SPy0093	adcC	adcC	87660	88379	+	ABC transporter (ATP-binding protein)	Best Blastp hit %3D emb|CAA96186.1| (Z71552) AdcC protein [Streptococcus pneumoniae]	gene	gene106	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0093
SPy_0094	SPy0094	adcB	adcB	88372	89187	+	putative ABC transporter (permease)	Best Blastp hit %3D emb|CAA96187.1| (Z71552) AdcB protein [Streptococcus pneumoniae]	gene	gene107	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0094
SPy_0095	SPy0095		SPy_0095	89227	89610	-	putative histidine triad (HIT) protein	Best Blastp hit %3D pir||B64408 histidine triad (HIT) protein MJ0866 - Methanococcus jannaschii	gene	gene108	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0095
SPy_0096	SPy0096	tyrS	tyrS	89661	90917	-	putative tyrosine-tRNA ligase	Best Blastp hit %3D sp|P00952|SYY_BACST TYROSYL-TRNA SYNTHETASE (TYROSINE-TRNA LIGASE) (TYRRS) >gi|68502|pir||SYBSYF tyrosine-tRNA ligase (EC 6.1.1.1) - Bacillus stearothermophilus >gi|230779|pdb|2TS1| Tyrosyl-Transfer RNA Synthetase (E.C.6.1.1.1) >gi|230940|pdb|3TS1| Tyrosyl-Transfer RNA Synthetase (E.C.6.1.1.1) Complexed With Tyrosinyl Adenylate	gene	gene109	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0096
SPy_0097	SPy0097	pbp1b	pbp1b	91009	93321	+	putative penicillin-binding protein 1b	Best Blastp hit %3D emb|CAA05302.1| (AJ002291) penicillin-binding protein 1b [Streptococcus pneumoniae] >gi|6165962|gb|AAF04736.1|AF101781_1 (AF101781) penicillin-binding protein 1b [Streptococcus pneumoniae]	gene	gene110	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0097
SPy_0098	SPy0098	rpoB	rpoB	93585	97151	+	putative DNA-dependent RNA polymerase subunit beta	Best Blastp hit %3D emb|CAB56706.1| (Y16468) DNA-dependent RNA polymerase subunit beta [Listeria monocytogenes]	gene	gene111	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0098
SPy_0099	SPy0099	rpoC	rpoC	97242	100883	+	DNA-dependent RNA polymerase%2C B' subunit	Best Blastp hit %3D sp|P95816|RPOC_STRPY DNA-DIRECTED RNA POLYMERASE BETA' CHAIN (TRANSCRIPTASE BETA' CHAIN) (RNA POLYMERASE BETA' SUBUNIT) >gi|1839027|emb|CAA65249.1| (X96385) DNA-dependent RNA polymerase [Streptococcus pyogenes]	gene	gene112	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0099
SPy_0100	SPy0100		SPy_0100	101035	101400	+	putative DNA binding protein	Best Blastp hit %3D gb|AAC45309.1| (U81957) putative DNA binding protein [Streptococcus gordonii]	gene	gene113	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0100
SPy_0101	SPy0101	comYA	comYA	101493	102431	+	putative ABC transporter subunit ComYA	Best Blastp hit %3D gb|AAC45310.1| (U81957) putative ABC transporter subunit ComYA [Streptococcus gordonii]	gene	gene114	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0101
SPy_0102	SPy0102	comYB	comYB	102553	103401	+	putative competence protein%2C ABC transporter subunit	Best Blastp hit %3D gb|AAC45311.1| (U81957) putative ABC transporter subunit ComYB [Streptococcus gordonii]	gene	gene115	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0102
SPy_0103	SPy0103	comYC	comYC	103403	103729	+	putative competence protein	Best Blastp hit %3D emb|CAA75317.1| (Y15043) homology to ComYC from Streptococcus gordonii%2C and ComGC from Bacillus subtilis [Lactococcus lactis subsp. cremoris]	gene	gene116	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0103
SPy_0104	SPy0104		SPy_0104	103704	104132	+	putative competence protein	Best Blastp hit %3D gb|AAC23740.1| (AF052207) competence protein [Streptococcus pneumoniae]	gene	gene117	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0104
SPy_0105	SPy0105		SPy_0105	104137	104373	+	hypothetical protein	Best Blastp hit %3D emb|CAA75316.1| (Y15043) hypothetical protein [Lactococcus lactis subsp. cremoris]	gene	gene118	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0105
SPy_0106	SPy0106	comYD	comYD	104366	104800	+	putative competence protein	Best Blastp hit %3D emb|CAA75315.1| (Y15043) homology to ComYD from Streptococcus gordonii%2C and ComGD from Bacillus subtilis [Lactococcus lactis subsp. cremoris]	gene	gene119	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0106
SPy_0107	SPy0107		SPy_0107	104784	105110	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene120	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0107
SPy_0108	SPy0108		SPy_0108	105208	106161	+	hypothetical protein	Best Blastp hit %3D sp|P37876|YTXK_BACSU HYPOTHETICAL 37.4 KD PROTEIN IN ACKA-SSPA INTERGENIC REGION >gi|7475419|pir||G70003 hypothetical protein ytxK - Bacillus subtilis >gi|2293239|gb|AAC00317.1| (AF008220) YtxK [Bacillus subtilis] >gi|2635432|emb|CAB14926.1| (Z99119) alternate gene name: ythI [Bacillus subtilis]	gene	gene121	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0108
SPy_0109	SPy0109	ackA	ackA	106220	107416	+	acetate kinase	Best Blastp hit %3D sp|P37877|ACKA_BACSU ACETATE KINASE (ACETOKINASE) >gi|1075817|pir||B49935 acetate kinase (EC 2.7.2.1) ackA - Bacillus subtilis >gi|405134|gb|AAC36857.1| (L17320) acetate kinase [Bacillus subtilis] >gi|2293240|gb|AAC00318.1| (AF008220) acetate kinase [Bacillus subtilis] >gi|2635431|emb|CAB14925.1| (Z99119) acetate kinase [Bacillus subtilis]	gene	gene122	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0109
SPy_0110	SPy0110		SPy_0110	107603	107911	+	hypothetical protein	Best Blastp hit %3D gb|AAD41947.1|AF160864_35 (AF160864) orf443 [Tetrahymena pyriformis]	gene	gene123	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0110
SPy_0112	SPy0112	proC	proC	107994	108764	-	putative pyrroline carboxylate reductase	Best Blastp hit %3D sp|Q04708|PROC_PEA PYRROLINE-5-CARBOXYLATE REDUCTASE (P5CR) (P5C REDUCTASE) >gi|7431797|pir||T06477 probable pyrroline-5-carboxylate reductase (EC 1.5.1.2) - garden pea >gi|20851|emb|CAA44646.1| (X62842) pyrroline carboxylate reductase [Pisum sativum] >gi|445614|prf||1909360A pyrroline carboxylate reductase [Pisum sativum]	gene	gene124	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0112
SPy_0115	SPy0115	pepA	pepA	108812	109879	-	putative glutamyl-aminopeptidase	Best Blastp hit %3D pir||B69998 endo-1%2C4-beta-glucanase homolog ytoP - Bacillus subtilis >gi|2293210|gb|AAC00288.1| (AF008220) YtoP [Bacillus subtilis] >gi|2635470|emb|CAB14964.1| (Z99119) similar to endo-1%2C4-beta-glucanase [Bacillus subtilis]	gene	gene125	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0115
SPy_0116	SPy0116		SPy_0116	109989	110153	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene126	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0116
SPy_0117	SPy0117		SPy_0117	110344	110628	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene127	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0117
SPy_0121	SPy0121		SPy_0121	112393	113034	-	putative deoxyguanosine kinase/deoxyadenosine kinase(I) subunit	Best Blastp hit %3D dbj|BAB16044.1| (AB030884) similar to Lactobacillus acidophilus dA/dG-kinase [Streptococcus zooepidemicus]	gene	gene128	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0121
SPy_0122	SPy0122		SPy_0122	113054	114031	-	possible transcriptional regulator	Best Blastp hit %3D gb|AAC97155.1| (U49397) unknown [Streptococcus pyogenes]	gene	gene129	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0122
SPy_0123	SPy0123		SPy_0123	114018	114890	-	putative heat shock protein HSP33	Best Blastp hit %3D dbj|BAB03806.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene130	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0123
SPy_0124	SPy0124	rofA	rofA	115037	116530	-	regulatory protein	Best Blastp hit %3D gb|AAC43219.1| (U01312) RofA [Streptococcus pyogenes]	gene	gene131	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0124
SPy_0127	SPy0127		SPy_0127	119221	119616	+	putative signal peptidase I	Best Blastp hit %3D gb|AAC97149.1| (U49397) LepA [Streptococcus pyogenes]	gene	gene132	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0127
SPy_0128	SPy0128		SPy_0128	119649	120671	+	hypothetical protein	Best Blastp hit %3D gb|AAC97152.1| (U49397) unknown [Streptococcus pyogenes]	gene	gene133	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0128
SPy_0129	SPy0129		SPy_0129	120681	121394	+	hypothetical protein	Best Blastp hit %3D gb|AAC97152.1| (U49397) unknown [Streptococcus pyogenes]	gene	gene134	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0129
SPy_0130	SPy0130		SPy_0130	121416	122063	+	hypothetical protein	Best Blastp hit %3D gb|AAC97151.1| (U49397) unknown [Streptococcus pyogenes]	gene	gene135	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0130
SPy_0131	SPy0131		SPy_0131	122250	123602	-	hypothetical protein	Best Blastp hit %3D emb|CAB54046.1| (AJ245436) hypothetical protein%2C 57.8 kD [Pseudomonas putida]	gene	gene136	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0131
SPy_0133	SPy0133		SPy_0133	123813	124163	-	hypothetical protein	Best Blastp hit %3D gi|10955400 orf50 [Escherichia coli] >gi|6009426|dbj|BAA84885.1| (AB024946) orf50 [Escherichia coli]	gene	gene137	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0133
SPy_0135	SPy0135		SPy_0135	124467	125222	+	putative fimbria-associated protein	Best Blastp hit %3D gb|AAC13546.1| (AF019629) putative fimbria-associated protein [Actinomyces naeslundii]	gene	gene138	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0135
SPy_0136	SPy0136		SPy_0136	125416	126081	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene139	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0136
SPy_0137	SPy0137	atoE	atoE	126460	127836	+	putative short-chain fatty acids transporter	Best Blastp hit %3D dbj|BAB04077.1| (AP001508) short-chain fatty acids transporter [Bacillus halodurans]	gene	gene140	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0137
SPy_0139	SPy0139		SPy_0139	127904	128814	-		*FRAME SHIFT* Best Blastp hit %3D sp|P39592|YWBI_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR YWBI >gi|629031|pir||S39679 transcription regulator homolog ywbI - Bacillus subtilis >gi|413948|emb|CAA51580.1| (X73124) ipa-24d [Bacillus subtilis] >gi|2636366|emb|CAB15857.1| (Z99123) alternate gene name: ipa-24d~similar to transcriptional regulator (LysR family) [Bacillus subtilis]	gene	gene141	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0139
SPy_0140	SPy0140		SPy_0140	128935	130119	+	putative acetyl-CoA acetyltransferase	Best Blastp hit %3D gb|AAG05389.1|AE004626_8 (AE004626) acetyl-CoA acetyltransferase [Pseudomonas aeruginosa]	gene	gene142	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0140
SPy_0141	SPy0141	atoD.2	atoD.2	130131	130790	+	putative acetyl-CoA:acetoacetyl-CoA transferase alpha subunit	Best Blastp hit %3D sp|P76458|ATOD_ECOLI ACETATE COA-TRANSFERASE ALPHA SUBUNIT (ACETYL-COA:ACETOACETATE COA TRANSFERASE) >gi|7434985|pir||C64992 atoD protein - Escherichia coli (strain K-12) >gi|1736876|dbj|BAA16017.1| (D90851) Acetyl-CoA:acetoacetyl-CoA transferase a subunit (EC 2.8.3.-). [Escherichia coli] >gi|1788551|gb|AAC75281.1| (AE000311) acetyl-CoA:acetoacetyl-CoA transferase alpha subunit [Escherichia coli]	gene	gene143	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0141
SPy_0142	SPy0142		SPy_0142	130793	131440	+	butyrate-acetoacetate CoA-transferase%2C beta subunit	Best Blastp hit %3D pir||E75600 butyrate-acetoacetate CoA-transferase (EC 2.8.3.9) large chain homolog DRA0067 [similarity] - Deinococcus radiodurans (strain R1) >gi|6460542|gb|AAF12248.1|AE001862_74 (AE001862) CoA transferase%2C subunit B [Deinococcus radiodurans]	gene	gene144	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0142
SPy_0144	SPy0144		SPy_0144	131562	132242	-	hypothetical protein	Best Blastp hit %3D sp|P44761|YHEO_HAEIN HYPOTHETICAL PROTEIN HI0575 >gi|1074447|pir||B64155 hypothetical protein HI0575 - Haemophilus influenzae (strain Rd KW20) >gi|1573564|gb|AAC22233.1| (U32739) conserved hypothetical protein [Haemophilus influenzae Rd]	gene	gene145	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0144
SPy_0145	SPy0145		SPy_0145	132416	132781	+	hypothetical protein	Best Blastp hit %3D pir||F72630 hypothetical protein APE1501 - Aeropyrum pernix (strain K1) >gi|5105186|dbj|BAA80500.1| (AP000061) 123aa long hypothetical protein [Aeropyrum pernix]	gene	gene146	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0145
SPy_0146	SPy0146		SPy_0146	132818	133837	+	putative regulatory protein	Best Blastp hit %3D pir||A43577 regulatory protein pfoR - Clostridium perfringens	gene	gene147	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0146
SPy_0147	SPy0147		SPy_0147	134292	134612	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene148	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0147
SPy_0148	SPy0148	ntpI	ntpI	134602	136602	+	V-type Na+ -ATPase subunit I	Best Blastp hit %3D sp|P43439|NTPI_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT I (NA(+)-TRANSLOCATING ATPASE SUBUNIT I) >gi|1075715|pir||B53610 ntpI protein - Enterococcus hirae >gi|487273|dbj|BAA04270.1| (D17462) Na+ -ATPase subunit I [Enterococcus hirae]	gene	gene149	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0148
SPy_0149	SPy0149	ntpK	ntpK	136604	137083	+	V-type Na+ -ATPase subunit K	Best Blastp hit %3D sp|P43457|NTPK_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT K (NA(+)-TRANSLOCATING ATPASE SUBUNIT K) (SODIUM ATPASE PROTEOLIPID COMPONENT) >gi|1075719|pir||C54392 Na+-ATPase complex 16K proteolipid chain - Enterococcus hirae >gi|416405|dbj|BAA03841.1| (D16334) Na+-ATPase K subunit [Enterococcus hirae] >gi|472919|emb|CAA54237.1| (X76913) v-type Na-ATPase [Enterococcus hirae] >gi|487274|dbj|BAA04271.1| (D17462) Na+ -ATPase subunit K [Enterococcus hirae]	gene	gene150	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0149
SPy_0150	SPy0150	ntpE	ntpE	137151	137735	+	putative V-type Na+ -ATPase subunit E	Best Blastp hit %3D sp|P43436|NTPE_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT E (NA(+)-TRANSLOCATING ATPASE SUBUNIT E) >gi|487275|dbj|BAA04272.1| (D17462) Na+ -ATPase subunit E [Enterococcus hirae]	gene	gene151	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0150
SPy_0151	SPy0151	ntpC	ntpC	137751	138749	+	putative V-type Na+ -ATPase subunit C	Best Blastp hit %3D sp|P43456|NTPC_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT C (NA(+)-TRANSLOCATING ATPASE SUBUNIT C) >gi|1075721|pir||E54392 ntpP protein - Enterococcus hirae >gi|472921|emb|CAA54239.1| (X76913) v-type Na-ATPase [Enterococcus hirae] >gi|487276|dbj|BAA04273.1| (D17462) Na+ -ATPase subunit C [Enterococcus hirae]	gene	gene152	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0151
SPy_0154	SPy0154	ntpA	ntpA	139267	141042	+	putative V-type Na+ -ATPase alpha subunit	Best Blastp hit %3D sp|Q08636|NTPA_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT A (NA(+)-TRANSLOCATING ATPASE SUBUNIT A) >gi|421413|pir||A46733 Na+-transporting ATPase (EC 3.6.1.-) chain A - Enterococcus hirae >gi|868004|dbj|BAA04275.1| (D17462) Na+ -ATPase subunit A [Enterococcus hirae] >gi|912449|dbj|BAA02969.1| (D13816) Na+ -ATPase alpha subunit [Enterococcus hirae]	gene	gene153	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0154
SPy_0155	SPy0155	ntpB	ntpB	141043	142458	+	putative V-type Na+ -ATPase subunit B	Best Blastp hit %3D sp|Q08637|NTPB_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT B (NA(+)-TRANSLOCATING ATPASE SUBUNIT B) >gi|421414|pir||B46733 Na+-transporting ATPase (EC 3.6.1.-) chain B - Enterococcus hirae >gi|391682|dbj|BAA02970.1| (D13816) Na+ -ATPase beta subunit [Enterococcus hirae] >gi|487279|dbj|BAA04276.1| (D17462) Na+ -ATPase subunit B [Enterococcus hirae]	gene	gene154	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0155
SPy_0157	SPy0157	ntpD	ntpD	142503	143129	+	putative V-type Na+ -ATPase subunit D	Best Blastp hit %3D sp|P43435|NTPD_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT D (NA(+)-TRANSLOCATING ATPASE SUBUNIT D) >gi|1075711|pir||F53610 H+-transporting ATP synthase (EC 3.6.1.34) chain D - Enterococcus hirae >gi|487280|dbj|BAA04277.1| (D17462) Na+ -ATPase subunit D [Enterococcus hirae]	gene	gene155	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0157
SPy_0158	SPy0158		SPy_0158	143249	144511	-	putative toxic anion resistance protein	Best Blastp hit %3D pir||B69757 toxic anion resistance protein homolog yceH - Bacillus subtilis >gi|2415745|dbj|BAA22255.1| (AB000617) YceH [Bacillus subtilis] >gi|2632580|emb|CAB12088.1| (Z99105) similar to toxic anion resistance protein [Bacillus subtilis]	gene	gene156	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0158
SPy_0159	SPy0159		SPy_0159	144524	145402	-	hypothetical protein	Best Blastp hit %3D gb|AAB02852.1| (U59243) apolipophorin-III precursor [Bombyx mori]	gene	gene157	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0159
SPy_0160	SPy0160	purA	purA	145840	147132	+	putative adenylosuccinate synthetase	Best Blastp hit %3D pir||A42280 adenylosuccinate synthase (EC 6.3.4.4) purA - Bacillus subtilis >gi|467328|dbj|BAA05174.1| (D26185) adenylosuccinate synthetase [Bacillus subtilis] >gi|2636589|emb|CAB16079.1| (Z99124) adenylosuccinate synthetase [Bacillus subtilis]	gene	gene158	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0160
SPy_0163	SPy0163		SPy_0163	147474	148502	+	putative ABC transporter (lipoprotein)	Best Blastp hit %3D sp|O05252|YUFN_BACSU HYPOTHETICAL LIPOPROTEIN YUFN PRECURSOR >gi|7429430|pir||C70009 ABC transporter (lipoprotein) homolog yufN - Bacillus subtilis >gi|1934811|emb|CAB07936.1| (Z93937) unknown [Bacillus subtilis] >gi|2635650|emb|CAB15143.1| (Z99120) similar to ABC transporter (lipoprotein) [Bacillus subtilis]	gene	gene159	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0163
SPy_0164	SPy0164	nusG	nusG	148675	149214	+	putative transcription antitermination factor	Best Blastp hit %3D sp|P36264|NUSG_STACA TRANSCRIPTION ANTITERMINATION PROTEIN NUSG >gi|487095|pir||S38870 transcription antitermination factor nusG - Staphylococcus carnosus >gi|426473|emb|CAA53738.1| (X76134) nusG [Staphylococcus carnosus]	gene	gene160	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0164
SPy_0165	SPy0165	nga	nga	149586	150929	+	nicotine adenine dinucleotide glycohydrolase precursor	Best Blastp hit %3D gb|AAF19837.1|AF203371_1 (AF203371) nicotine adenine dinucleotide glycohydrolase precursor [Streptococcus pyogenes] >gi|6635479|gb|AAF19838.1|AF203372_1 (AF203372) nicotine adenine dinucleotide glycohydrolase precursor [Streptococcus pyogenes]	gene	gene161	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0165
SPy_0166	SPy0166		SPy_0166	151063	151419	+	hypothetical protein	Best Blastp hit %3D gb|AAB37625.1| (U80437) C43E11.11 gene product [Caenorhabditis elegans]	gene	gene162	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0166
SPy_0167	SPy0167	slo	slo	151443	153158	+	streptolysin O precursor	Best Blastp hit %3D sp|P21131|TACY_STRPY STREPTOLYSIN O PRECURSOR (THIOL-ACTIVATED CYTOLYSIN) >gi|98069|pir||A43507 streptolysin O precursor - Streptococcus pyogenes >gi|153811|gb|AAA26975.1| (M18638) streptolysin O precursor (put.%3B start may be at 190)%3B putative [Plasmid pMK157]	gene	gene163	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0167
SPy_0168	SPy0168		SPy_0168	153408	153836	+	hypothetical protein	Best Blastp hit %3D gb|AAF63946.1|AF157531_1 (AF157531) IceA1 [Helicobacter pylori]	gene	gene164	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0168
SPy_0169	SPy0169		SPy_0169	154038	154238	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene165	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0169
SPy_0170	SPy0170		SPy_0170	154650	154817	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene166	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0170
SPy_0171	SPy0171		SPy_0171	155002	155328	-	hypothetical protein	Best Blastp hit %3D sp|Q90827|NEL_CHICK NEL PROTEIN PRECURSOR (93 KD PROTEIN) >gi|1483184|dbj|BAA13167.1| (D86747) Mr 93 K protein [Gallus gallus]	gene	gene167	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0171
SPy_0172	SPy0172	metB	metB	155812	156951	+	putative cystathionine beta-lyase	Best Blastp hit %3D dbj|BAB05347.1| (AP001512) cystathionine beta-lyase [Bacillus halodurans]	gene	gene168	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0172
SPy_0173	SPy0173	leuS	leuS	157126	159627	+	putative leucyl-tRNA synthetase	Best Blastp hit %3D sp|P36430|SYL_BACSU LEUCYL-TRNA SYNTHETASE (LEUCINE-TRNA LIGASE) (LEURS) >gi|7437539|pir||D69650 leucine-tRNA ligase (EC 6.1.1.4) - Bacillus subtilis >gi|2293181|gb|AAC00259.1| (AF008220) leucine tRNA synthetase [Bacillus subtilis] >gi|2635516|emb|CAB15010.1| (Z99119) leucyl-tRNA synthetase [Bacillus subtilis]	gene	gene169	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0173
SPy_0174	SPy0174		SPy_0174	159940	161367	+	hypothetical protein	Best Blastp hit %3D sp|P39301|SGAT_ECOLI PUTATIVE TRANSPORT PROTEIN SGAT >gi|7466018|pir||D65230 hypothetical 52.9 kD protein in aidB-rpsF intergenic region - Escherichia coli (strain K-12) >gi|2367358|gb|AAC77150.1| (AE000491) orf%2C hypothetical protein [Escherichia coli]	gene	gene170	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0174
SPy_0175	SPy0175		SPy_0175	161438	161716	+	hypothetical protein	Best Blastp hit %3D sp|P39302|PTXB_ECOLI UNKNOWN PENTITOL PHOSPHOTRANSFERASE ENZYME II%2C B COMPONENT >gi|1361123|pir||S56419 hypothetical 10.9K protein (aidB-rpsF intergenic region) - Escherichia coli >gi|537035|gb|AAA97090.1| (U14003) ORF_o101 [Escherichia coli] >gi|1790638|gb|AAC77151.1| (AE000491) orf%2C hypothetical protein [Escherichia coli]	gene	gene171	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0175
SPy_0176	SPy0176		SPy_0176	161838	162323	+	hypothetical protein	Best Blastp hit %3D pir||S56420 hypothetical protein o158 - Escherichia coli >gi|537036|gb|AAA97091.1| (U14003) ORF_o158 [Escherichia coli]	gene	gene172	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0176
SPy_0177	SPy0177		SPy_0177	162414	163076	+	putative hexulose-6-phosphate synthase	Best Blastp hit %3D sp|P39304|SGAH_ECOLI PROBABLE HEXULOSE-6-PHOSPHATE SYNTHASE (HUMPS) (D-ARABINO 3-HEXULOSE 6-PHOSPHATE FORMALDEHYDE LYASE) >gi|1361156|pir||S56421 hypothetical 23.6K protein (aidB-rpsF intergenic region) - Escherichia coli >gi|537037|gb|AAA97092.1| (U14003) ORF_o216 [Escherichia coli] >gi|1790640|gb|AAC77153.1| (AE000491) probable hexulose-6-phosphate synthase [Escherichia coli]	gene	gene173	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0177
SPy_0178	SPy0178		SPy_0178	163081	163944	+	putative hexulose-6-phosphate isomerase	Best Blastp hit %3D sp|P44990|SGBU_HAEIN PUTATIVE HEXULOSE-6-PHOSPHATE ISOMERASE (HUMPI) >gi|1074611|pir||G64164 hypothetical protein HI1026 - Haemophilus influenzae (strain Rd KW20) >gi|1574058|gb|AAC22686.1| (U32783) hexulose-6-phosphate isomerase%2C putative [Haemophilus influenzae Rd]	gene	gene174	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0178
SPy_0179	SPy0179	araD	araD	163946	164650	+	putative L-ribulose 5-phosphate 4-epimerase	Best Blastp hit %3D gb|AAD45716.1|AF160811_4 (AF160811) L-ribulose 5-phosphate 4-epimerase [Bacillus stearothermophilus]	gene	gene175	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0179
SPy_0180	SPy0180		SPy_0180	164708	164854	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene176	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0180
SPy_0181	SPy0181		SPy_0181	164978	166621	+	putative transcriptional regulator	Best Blastp hit %3D dbj|BAB03939.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene177	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0181
SPy_0182	SPy0182		SPy_0182	166874	167965	+	hypothetical protein	Best Blastp hit %3D sp|P39300|YJFR_ECOLI HYPOTHETICAL 40.1 KD PROTEIN IN AIDB-SGAT INTERGENIC REGION	gene	gene178	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0182
SPy_0183	SPy0183	opuAA	opuAA	168453	169649	+	putative glycine betaine/proline ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAF37878.1|AF234619_1 (AF234619) OpuAA [Lactococcus lactis]	gene	gene179	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0183
SPy_0184	SPy0184	opuABC	opuABC	169665	171392	+	putative glycine-betaine binding permease protein	Best Blastp hit %3D gb|AAF37879.1|AF234619_2 (AF234619) OpuABC [Lactococcus lactis]	gene	gene180	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0184
SPy_0185	SPy0185	polA	polA	171523	174165	+	DNA-directed DNA polymerase I	Best Blastp hit %3D sp|P13252|DPO1_STRPN DNA POLYMERASE I (POL I) >gi|98023|pir||A32949 DNA-directed DNA polymerase (EC 2.7.7.7) - Streptococcus pneumoniae >gi|153765|gb|AAA26954.1| (J04479) DNA polymerase I [Streptococcus pneumoniae]	gene	gene181	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0185
SPy_0186	SPy0186		SPy_0186	174352	174807	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05860.1| (AP001514) unknown conserved protein [Bacillus halodurans]	gene	gene182	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0186
SPy_0187	SPy0187	spf	spf	174859	175326	+	Ferric transport regulator protein	Best Blastp hit %3D gb|AAB18795.1| (U76538) Fur-like protein [Streptococcus pyogenes]	gene	gene183	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0187
SPy_0188	SPy0188	vlg	vlg	175482	175781	+	regulatory protein	Best Blastp hit %3D gb|AAB18796.1| (U76538) VirR-like protein [Streptococcus pyogenes]	gene	gene184	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0188
SPy_0189	SPy0189		SPy_0189	176003	177337	+	hypothetical protein	Best Blastp hit %3D gb|AAG05515.1|AE004640_4 (AE004640) conserved hypothetical protein [Pseudomonas aeruginosa]	gene	gene185	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0189
SPy_0190	SPy0190		SPy_0190	177330	177860	+	hypothetical protein	Best Blastp hit %3D dbj|BAA35231.1| (D90701) ORF_ID:o166#4 [Escherichia coli]	gene	gene186	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0190
SPy_0191a	SPy0191a		SPy_0191a	177853	178062	+	hypothetical protein	Best Blastp hit %3D emb|CAA59773.1| (X85787) tasA [Streptococcus pneumoniae]	gene	gene187	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0191a
SPy_0191b	SPy0191b		SPy_0191b	178259	179338	-		putative transposase - IS1076-like%3B there are several frame shifts within this gene. The transposase may be translated through a frameshift motif	gene	gene188	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0191b
SPy_0195	SPy0195		SPy_0195	179045	179338	-	hypothetical protein	Best Blastp hit %3D gb|AAF27305.1|AF154674_6 (AF154674) unknown [Lactococcus lactis subsp. lactis] >gi|6739596|gb|AAF27329.1| (AF178424) unknown [Lactococcus lactis]	gene	gene189	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0195
SPy_0196	SPy0196		SPy_0196	179416	180726	-	putative integral membrane protein	Best Blastp hit %3D gb|AAC97122.1| (U66846) orf5 [Streptococcus pneumoniae]	gene	gene190	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0196
SPy_0197	SPy0197	nadC	nadC	180950	181822	+	putative nicotinate-nucleotide pyrophosphorylase	Best Blastp hit %3D sp|P77938|NADC_RHORU PROBABLE NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE [CARBOXYLATING] (QUINOLINATE PHOSPHORIBOSYLTRANSFERASE [DECARBOXYLATING]) (QAPRTASE) >gi|11280012|pir||T51326 nicotinate-nucleotide pyrophosphorylase (carboxylating) (EC 2.4.2.19) [imported] - Rhodospirillum rubrum >gi|1498753|gb|AAC45128.1| (U65510) nicotinate-nucleotide pyrophosphorylase [Rhodospirillum rubrum]	gene	gene191	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0197
SPy_0198	SPy0198		SPy_0198	182122	182928	-	putative transposase%2C IS861	Best Blastp hit %3D gb|AAF73806.1|AF154034_3 (AF154034) IS3-Spn1 putative transposase [Streptococcus pneumoniae]	gene	gene192	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0198
SPy_0199	SPy0199		SPy_0199	182949	183464	-	conserved hypothetical protein%2C IS861 associated	Best Blastp hit %3Dgb|AAF73805.1|AF154034_2 (AF154034) hypothetical protein [Streptococcus pneumoniae]	gene	gene193	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0199
SPy_0201	SPy0201		SPy_0201	183550	184413	-	hypothetical protein	Best Blastp hit %3D pir||S32215 hypothetical protein 1 - Bacillus megaterium >gi|288299|emb|CAA79984.1| (Z21972) ORF1 [Bacillus megaterium]	gene	gene194	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0201
SPy_0203	SPy0203	tgt	tgt	184632	185774	+	putative tRNA-guanine transglycosylase	Best Blastp hit %3D sp|O32053|TGT_BACSU QUEUINE TRNA-RIBOSYLTRANSFERASE (TRNA-GUANINE TRANSGLYCOSYLASE) (GUANINE INSERTION ENZYME) >gi|7448762|pir||B69722 queuine tRNA-ribosyltransferase (EC 2.4.2.29) - Bacillus subtilis >gi|2635236|emb|CAB14731.1| (Z99118) tRNA-guanine transglycosylase [Bacillus subtilis] >gi|6977808|emb|CAB75333.1| (Y15896) tRNA-guanine transglycosylase [Bacillus subtilis]	gene	gene195	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0203
SPy_0205	SPy0205		SPy_0205	185991	186302	+	hypothetical protein	Best Blastp hit %3D pir||T38499 hypothetical protein SPAC29B12.12 - fission yeast (Schizosaccharomyces pombe) >gi|2408053|emb|CAB16256.1| (Z99164) hypothetical protein [Schizosaccharomyces pombe]	gene	gene196	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0205
SPy_0207	SPy0207		SPy_0207	186306	186845	+	putative biotin synthase	Best Blastp hit %3D pir||C75270 probable biotin synthase - Deinococcus radiodurans (strain R1) >gi|6460290|gb|AAF12013.1|AE002076_5 (AE002076) biotin synthase%2C putative [Deinococcus radiodurans]	gene	gene197	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0207
SPy_0208	SPy0208		SPy_0208	186985	187764	+	hypothetical protein	Best Blastp hit %3D pir||F69830 conserved hypothetical protein yhfI - Bacillus subtilis >gi|2226242|emb|CAA74530.1| (Y14083) hypothetical protein [Bacillus subtilis] >gi|2633360|emb|CAB12864.1| (Z99109) similar to hypothetical proteins [Bacillus subtilis]	gene	gene198	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0208
SPy_0210	SPy0210		SPy_0210	188893	190125	-	hypothetical protein	Best Blastp hit %3D emb|CAC12744.1| (AJ293727) Ky protein [Mus musculus]	gene	gene199	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0210
SPy_0212	SPy0212	speG	speG	190525	191229	+	exotoxin G precursor	Best Blastp hit %3D gb|AAD30988.1|AF124499_1 (AF124499) exotoxin G precursor [Streptococcus pyogenes]	gene	gene200	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0212
SPy_0215	SPy0215	pgi	pgi	191685	193034	+	glucose-6-phosphate isomerase	Best Blastp hit %3D gb|AAD33517.1|AF132127_2 (AF132127) glucose-6-phosphate isomerase [Streptococcus mutans]	gene	gene201	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0215
SPy_0216	SPy0216		SPy_0216	193383	194891	-	putative regulatory protein - RofA related	Best Blastp hit %3D >gb|AAB81298.1| (U53825) RofA [Streptococcus pyogenes]	gene	gene202	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0216
SPy_0217	SPy0217		SPy_0217	195446	196565	+		IS1548 transposase%3B There is a 10bp deletion confirmed by sequence analysis that results in a frame shift mutation located near the center of this gene.~	gene	gene203	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0217
SPy_0219	SPy0219		SPy_0219	196573	196677	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene204	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0219
SPy_0223	SPy0223		SPy_0223	196893	197564	+	hypothetical protein	Best Blastp hit %3D emb|CAB90755.1| (AJ400707) hypothetical protein [Streptococcus uberis]	gene	gene205	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0223
SPy_0224	SPy0224	hasC.2	hasC.2	197663	198562	-	putative UDP-glucose pyrophosphorylase	Best Blastp hit %3D emb|CAB90754.1| (AJ400707) putative UDP-glucose pyrophosphorylase [Streptococcus uberis]	gene	gene206	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0224
SPy_0226	SPy0226	gpsA	gpsA	198595	199611	-	putative NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	Best Blastp hit %3D pir||H69636 glycerol-3-phosphate dehydrogenase (NAD+) (EC 1.1.1.8) gpsA - Bacillus subtilis >gi|1146220|gb|AAC83967.1| (L47648) NAD+ dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis] >gi|2634701|emb|CAB14199.1| (Z99115) NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus subtilis]	gene	gene207	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0226
SPy_0228	SPy0228		SPy_0228	199909	200358	+	hypothetical protein	Best Blastp hit %3D sp|P37503|YYBA_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN COTF-TETB INTERGENIC REGION >gi|2127004|pir||S65996 transcription regulator homolog yybA - Bacillus subtilis >gi|467356|dbj|BAA05202.1| (D26185) unknown [Bacillus subtilis] >gi|2636618|emb|CAB16108.1| (Z99124) similar to transcriptional regulator (MarR family) [Bacillus subtilis]	gene	gene208	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0228
SPy_0229	SPy0229		SPy_0229	200351	202057	+	putative ABC transporter%2C ATP-binding protein	Best Blastp hit %3D pir||E72396 ABC transporter%2C ATP-binding protein - Thermotoga maritima (strain MSB8) >gi|4980785|gb|AAD35375.1|AE001710_10 (AE001710) ABC transporter%2C ATP-binding protein [Thermotoga maritima]	gene	gene209	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0229
SPy_0230	SPy0230		SPy_0230	202060	203844	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAD01950.1| (AF033015) ABC transporter homolog Z [Listeria monocytogenes]	gene	gene210	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0230
SPy_0233	SPy0233		SPy_0233	203962	204729	+	hypothetical protein	Best Blastp hit %3D pir||C70361 conserved hypothetical protein aq_701 - Aquifex aeolicus >gi|2983299|gb|AAC06891.1| (AE000703) hypothetical protein [Aquifex aeolicus]	gene	gene211	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0233
SPy_0235	SPy0235		SPy_0235	204839	205285	+	putative dUTPase%2C phage associated	Best Blastp hit %3D emb|CAA72644.1| (Y11901) dUTPase [Lactococcus lactis]	gene	gene212	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0235
SPy_0236	SPy0236	sms	sms	205366	206727	+	putative DNA repair protein	Best Blastp hit %3D sp|P37572|RADA_BACSU DNA REPAIR PROTEIN RADA HOMOLOG (DNA REPAIR PROTEIN SMS HOMOLOG) >gi|2127055|pir||S66116 DNA repair protein sms - Bacillus subtilis >gi|467475|dbj|BAA05321.1| (D26185) unknown [Bacillus subtilis] >gi|2632354|emb|CAB11863.1| (Z99104) DNA repair protein homolog [Bacillus subtilis]	gene	gene213	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0236
SPy_0237	SPy0237		SPy_0237	206916	207413	+	hypothetical protein	Best Blastp hit %3D sp|Q10612|YC84_MYCTU HYPOTHETICAL 18.2 KDA PROTEIN RV1284 >gi|7450690|pir||H70771 hypothetical protein Rv1284 - Mycobacterium tuberculosis (strain H37RV) >gi|1322408|emb|CAA97750.1| (Z73419) hypothetical protein Rv1284 [Mycobacterium tuberculosis]	gene	gene214	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0237
SPy_0238	SPy0238		SPy_0238	207559	208254	+	hypothetical protein	Best Blastp hit %3D pir||H75211 hypothetical protein PAB2205 - Pyrococcus abyssi (strain Orsay) >gi|5457652|emb|CAB49143.1| (AJ248283) hypothetical protein [Pyrococcus abyssi]	gene	gene215	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0238
SPy_0239	SPy0239	gltX	gltX	208436	209881	+	putative glutamyl-tRNA synthetase	Best Blastp hit %3D sp|P22250|SYE_BACSU GLUTAMYL-TRNA SYNTHETASE (GLUTAMATE-TRNA LIGASE) (GLURS) >gi|68552|pir||SYBSET glutamate-tRNA ligase (EC 6.1.1.17) gltX - Bacillus subtilis >gi|143006|gb|AAA22495.1| (M55073) transfer RNA-Gln synthetase [Bacillus subtilis] >gi|289282|gb|AAA21796.1| (L14580) glutamyl-tRNA synthetase [Bacillus subtilis] >gi|467480|dbj|BAA05326.1| (D26185) glutamyl-tRNA synthetase [Bacillus subtilis] >gi|2632359|emb|CAB11868.1| (Z99104) glutamyl-tRNA synthetase [Bacillus subtilis] >gi|2653659|gb|AAC31971.1| (U49789) glutamyl-tRNA synthetase [Bacillus subtilis]	gene	gene216	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0239
SPy_0242	SPy0242		SPy_0242	210276	211622	+	putative histidine kinase%2C possibly involved in competence	Best Blastp hit %3D emb|CAC10171.1| (AJ278301) histidine kinase [Streptococcus pneumoniae]	gene	gene217	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0242
SPy_0244	SPy0244		SPy_0244	211619	212902	+	putative histidine kinase	Best Blastp hit %3D emb|CAC10175.1| (AJ278302) histidine kinase [Streptococcus pneumoniae]	gene	gene218	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0244
SPy_0245	SPy0245		SPy_0245	212906	213646	+	putative response regulator	Best Blastp hit %3D emb|CAC10174.1| (AJ278302) response regulator [Streptococcus pneumoniae]	gene	gene219	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0245
SPy_0246	SPy0246	rnpA	rnpA	214186	214545	+	putative ribonuclease P protein component	Best Blastp hit %3D pdb|1A6F| Rnase P Protein From Bacillus Subtilis	gene	gene220	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0246
SPy_0247	SPy0247		SPy_0247	214511	215338	+	hypothetical protein	Best Blastp hit %3D sp|Q01625|SP3J_BACSU STAGE III SPORULATION PROTEIN J PRECURSOR >gi|2127241|pir||I40437 stage III sporulation protein spoIIIJ - Bacillus subtilis >gi|40023|emb|CAA44401.1| (X62539) unnamed protein product [Bacillus subtilis] >gi|467388|dbj|BAA05234.1| (D26185) stage III sporulation [Bacillus subtilis] >gi|2636651|emb|CAB16141.1| (Z99124) alternate gene name: spo0J87 [Bacillus subtilis]	gene	gene221	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0247
SPy_0248	SPy0248		SPy_0248	215350	216264	+	hypothetical protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||E72251 hypothetical protein TM1460 - Thermotoga maritima (strain MSB8) >gi|4982025|gb|AAD36528.1|AE001797_8 (AE001797) jag protein%2C putative [Thermotoga maritima]	gene	gene222	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0248
SPy_0250	SPy0250	rpmH	rpmH	216579	216713	+	50S ribosomal protein L34	Best Blastp hit %3D sp|P45647|RL34_COXBU 50S RIBOSOMAL PROTEIN L34 >gi|2119151|pir||I40651 ribosomal protein L34 - Coxiella burnetii >gi|511456|gb|AAA56916.1| (U10529) ribosomal protein L34 [Coxiella burnetii]	gene	gene223	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0250
SPy_0251	SPy0251		SPy_0251	216987	217691	+	putative N-acetylmannosamine-6-P epimerase	Best Blastp hit %3D gb|AAD28762.1|AF130859_1 (AF130859) putative N-acetylmannosamine-6-P epimerase [Clostridium perfringens]	gene	gene224	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0251
SPy_0252	SPy0252		SPy_0252	217740	219059	+	putative sugar transporter sugar binding lipoprotein	Best Blastp hit %3D pir||F69796 sugar-binding protein homolog yesO - Bacillus subtilis >gi|2633010|emb|CAB12516.1| (Z99107) similar to sugar-binding protein [Bacillus subtilis]	gene	gene225	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0252
SPy_0254	SPy0254		SPy_0254	219087	220049	+	sugar transport system (permease)	Best Blastp hit %3D dbj|BAB05584.1| (AP001513) sugar transport system (permease) (binding protein dependent transporter) [Bacillus halodurans]	gene	gene226	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0254
SPy_0255	SPy0255		SPy_0255	220062	220892	+	probable sugar transport protein (permease)	Best Blastp hit %3D emb|CAB59597.1| (AL132662) probable sugar transport inner membrane protein [Streptomyces coelicolor A3(2)]	gene	gene227	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0255
SPy_0256	SPy0256		SPy_0256	221049	221711	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05582.1| (AP001513) unknown conserved protein in bacilli [Bacillus halodurans]	gene	gene228	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0256
SPy_0257	SPy0257	nanH	nanH	221723	222637	+	putative acylneuraminate lyase	Best Blastp hit %3D emb|CAA69950.1| (Y08695) putative acylneuraminate lyase [Clostridium tertium]	gene	gene229	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0257
SPy_0258	SPy0258		SPy_0258	222659	223597	+	putative glucose kinase	Best Blastp hit %3D dbj|BAB04516.1| (AP001509) glucose kinase [Bacillus halodurans]	gene	gene230	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0258
SPy_0259	SPy0259		SPy_0259	223708	224538	-	hypothetical protein	Best Blastp hit %3D sp|P44540|Y143_HAEIN HYPOTHETICAL PROTEIN HI0143 >gi|1573099|gb|AAC21815.1| (U32700) conserved hypothetical protein [Haemophilus influenzae Rd]	gene	gene231	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0259
SPy_0260	SPy0260		SPy_0260	224790	225614	+	hypothetical protein	Best Blastp hit %3D sp|P37545|YABD_BACSU PUTATIVE DEOXYRIBONUCLEASE YABD >gi|2127033|pir||S66068 conserved hypothetical protein yabD - Bacillus subtilis >gi|467428|dbj|BAA05274.1| (D26185) unknown [Bacillus subtilis] >gi|2632306|emb|CAB11815.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene232	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0260
SPy_0261	SPy0261		SPy_0261	225607	226176	+	hypothetical protein	Best Blastp hit %3D sp|P37547|YABF_BACSU HYPOTHETICAL 20.7 KD PROTEIN IN METS-KSGA INTERGENIC REGION >gi|2127035|pir||S66070 conserved hypothetical protein yabF - Bacillus subtilis >gi|467430|dbj|BAA05276.1| (D26185) unknown [Bacillus subtilis] >gi|2632308|emb|CAB11817.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene233	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0261
SPy_0262	SPy0262	ksgA	ksgA	226290	227162	+	putative dimethyladenosine transferase	Best Blastp hit %3D sp|P37468|KSGA_BACSU DIMETHYLADENOSINE TRANSFERASE (S-ADENOSYLMETHIONINE-6-N'%2C N'-ADENOSYL(RRNA) DIMETHYLTRANSFERASE) (16S RRNA DIMETHYLASE) (HIGH LEVEL KASUGAMYCIN RESISTANCE PROTEIN KSGA) (KASUGAMYCIN DIMETHYLTRANSFERASE) >gi|2126951|pir||S66071 probable (adenine-N6%2CN6-)-dimethyltransferase (EC 2.1.1.-) ksgA - Bacillus subtilis >gi|467431|dbj|BAA05277.1| (D26185) high level kasgamycin resistance [Bacillus subtilis] >gi|2632309|emb|CAB11818.1| (Z99104) dimethyladenosine transferase [Bacillus subtilis]	gene	gene234	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0262
SPy_0263	SPy0263		SPy_0263	227586	228458	+	hypothetical protein	Best Blastp hit %3D pir||A69879 conserved hypothetical protein yloQ - Bacillus subtilis >gi|2337807|emb|CAA74251.1| (Y13937) YloQ protein [Bacillus subtilis] >gi|2633950|emb|CAB13451.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene235	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0263
SPy_0264	SPy0264	rpe	rpe	228468	229130	+	putative ribulose-phosphate 3-epimerase	Best Blastp hit %3D dbj|BAB06221.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene236	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0264
SPy_0265	SPy0265		SPy_0265	229123	229755	+	hypothetical protein	Best Blastp hit %3D pir||C69879 hypothetical protein yloS - Bacillus subtilis >gi|2337809|emb|CAA74253.1| (Y13937) YloS protein [Bacillus subtilis] >gi|2633952|emb|CAB13453.1| (Z99112) yloS [Bacillus subtilis]	gene	gene237	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0265
SPy_0266	SPy0266		SPy_0266	229757	231028	+	hypothetical protein	Best Blastp hit %3D gb|AAF83223.1|AE003892_8 (AE003892) conserved hypothetical protein [Xylella fastidiosa]	gene	gene238	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0266
SPy_0267	SPy0267	cbf	cbf	231018	231956	+	putative CMP-binding factor	Best Blastp hit %3D pir||G69818 CMP-binding factor homolog yhaM - Bacillus subtilis >gi|2226127|emb|CAA74420.1| (Y14078) Hypothetical protein [Bacillus subtilis] >gi|2633329|emb|CAB12833.1| (Z99109) similar to CMP-binding factor [Bacillus subtilis]	gene	gene239	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0267
SPy_0268	SPy0268	purR	purR	232223	233062	+	putative purine operon repressor	Best Blastp hit %3D emb|CAA10902.1| (AJ222642) purR [Lactococcus lactis]	gene	gene240	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0268
SPy_0269	SPy0269	prgA	prgA	233053	235674	+	putative surface exclusion protein	Best Blastp hit %3D pir||G41662 130K surface exclusion protein Sec10 precursor - Enterococcus faecalis plasmid pCF10 >gi|150554|gb|AAA65847.1| (M64978) surface exclusion protein [Plasmid pCF10]	gene	gene241	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0269
SPy_0271	SPy0271	rpsL	rpsL	235882	236295	+	30S ribosomal protein S12	Best Blastp hit %3D sp|P30891|RS12_STRPN 30S RIBOSOMAL PROTEIN S12 >gi|282336|pir||S26680 ribosomal protein S12 - Streptococcus pneumoniae >gi|47453|emb|CAA78825.1| (Z15120) ribosomal protein S12 [Streptococcus pneumoniae]	gene	gene242	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0271
SPy_0272	SPy0272	rpsG	rpsG	236316	236786	+	30S ribosomal protein S7	Best Blastp hit %3D sp|P21469|RS7_BACSU 30S RIBOSOMAL PROTEIN S7 (BS7) >gi|7440222|pir||F69699 ribosomal protein S7 (rpsG) - Bacillus subtilis >gi|1644222|dbj|BAA11002.1| (D64127) ribosomal protein S7 [Bacillus subtilis] >gi|2632378|emb|CAB11887.1| (Z99104) ribosomal protein S7 (BS7) [Bacillus subtilis]	gene	gene243	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0272
SPy_0273	SPy0273	fus	fus	237153	239231	+	translation elongation factor G%2C EF-G	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAC09927.1| (AJ249559) translation elongation factor G%2C EF-G [Bacillus stearothermophilus]	gene	gene244	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0273
SPy_0274	SPy0274	plr	plr	239579	240589	+	glyceraldehyde-3-phosphate dehydrogenase%2C plasmin receptor	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P50467|G3P_STRPY GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE (GAPDH) (PLASMINOGEN-BINDING PROTEIN) (PLASMIN RECEPTOR) >gi|285385|pir||A42963 glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) - Streptococcus sp >gi|153763|gb|AAA26953.1| (M95569) plasmin receptor [Streptococcus pyogenes]	gene	gene245	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0274
SPy_0276	SPy0276		SPy_0276	241073	241813	-	putative amino acid ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||H69334 glutamine transport protein glnQ - Archaeoglobus fulgidus >gi|2649950|gb|AAB90561.1| (AE001058) glutamine ABC transporter%2C ATP-binding protein (glnQ) [Archaeoglobus fulgidus]	gene	gene246	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0276
SPy_0277	SPy0277		SPy_0277	241806	243374	-	putative glutamine-binding periplasmic protein	Best Blastp hit %3D pir||S77250 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1652664|dbj|BAA17584.1| (D90907) glutamine-binding periplasmic protein [Synechocystis sp.]	gene	gene247	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0277
SPy_0278	SPy0278		SPy_0278	243572	245470	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene248	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0278
SPy_0280	SPy0280	bacA	bacA	245536	246375	+	putative undecaprenol kinase (bacitracin resistance protein)	Best Blastp hit %3D gb|AAD50462.1|AF169967_5 (AF169967) BacA [Flavobacterium johnsoniae]	gene	gene249	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0280
SPy_0281	SPy0281	mecA	mecA	246521	247282	+	putative negative regulator of genetic competence	Best Blastp hit %3D dbj|BAA82113.1| (AB022909) negative regulator of genetic competence [Streptococcus mutans]	gene	gene250	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0281
SPy_0282	SPy0282	rgpG	rgpG	247289	248458	+	possibly involved in regulation of genetic competence	Best Blastp hit %3D dbj|BAA82114.1| (AB022909) RgpG [Streptococcus mutans]	gene	gene251	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0282
SPy_0285	SPy0285		SPy_0285	248580	249350	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P80866|V296_BACSU VEGETATIVE PROTEIN 296 (VEG296) >gi|7445790|pir||H70019 ABC transporter (ATP-binding protein) homolog yurY - Bacillus subtilis >gi|2635767|emb|CAB15260.1| (Z99120) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene252	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0285
SPy_0287	SPy0287		SPy_0287	249445	250707	+	hypothetical protein	Best Blastp hit %3D pir||G70019 conserved hypothetical protein yurX - Bacillus subtilis >gi|2635766|emb|CAB15259.1| (Z99120) similar to hypothetical proteins [Bacillus subtilis]	gene	gene253	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0287
SPy_0288	SPy0288		SPy_0288	250738	251964	+	putative aminotransferase	Best Blastp hit %3D pir||F70019 nifS protein homolog yurW - Bacillus subtilis >gi|2635765|emb|CAB15258.1| (Z99120) similar to NifS protein homolog [Bacillus subtilis]	gene	gene254	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0288
SPy_0289	SPy0289		SPy_0289	251951	252430	+	NifU-like protein	Best Blastp hit %3D sp|O32163|NIFU_BACSU NIFU-LIKE PROTEIN >gi|7427865|pir||E70019 nitrogen fixation protein nifU homolog yurV - Bacillus subtilis >gi|2635764|emb|CAB15257.1| (Z99120) similar to NifU protein homolog [Bacillus subtilis]	gene	gene255	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0289
SPy_0290	SPy0290		SPy_0290	252423	253841	+	hypothetical protein	Best Blastp hit %3D pir||D70019 conserved hypothetical protein yurU - Bacillus subtilis >gi|2635763|emb|CAB15256.1| (Z99120) similar to hypothetical proteins [Bacillus subtilis]	gene	gene256	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0290
SPy_0292	SPy0292	dacA	dacA	255342	256574	-	penicillin-binding protein (D-alanyl-D-alanine carboxypeptidase)	Best Blastp hit %3D emb|CAA67776.1| (X99400) D%2CD-carboxypeptidase [Streptococcus pneumoniae]	gene	gene257	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0292
SPy_0294	SPy0294	oppB	oppB	258940	260442	+	oligopeptidepermease	Best Blastp hit %3D emb|CAA61523.1| (X89237) oligopeptidepermease [Streptococcus pyogenes]	gene	gene258	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0294
SPy_0295	SPy0295	oppC	oppC	260442	261368	+	oligopeptidepermease	Best Blastp hit %3D emb|CAA61524.1| (X89237) oligopeptidepermease [Streptococcus pyogenes]	gene	gene259	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0295
SPy_0296	SPy0296	oppD	oppD	261377	262447	+	oligopeptidepermease (ATP-binding protein)	Best Blastp hit %3D emb|CAA61525.1| (X89237) oligopeptidepermease [Streptococcus pyogenes]	gene	gene260	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0296
SPy_0297	SPy0297	oppF	oppF	262440	263363	+	oligopeptidepermease	Best Blastp hit %3D gb|AAG32327.1| (AF305548) oligopeptidepermease [Streptococcus pyogenes]	gene	gene261	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0297
SPy_0298	SPy0298		SPy_0298	263407	263484	-			gene	gene262	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0298
SPy_0299	SPy0299		SPy_0299	263550	263937	-			gene	gene263	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0299
SPy_0300	SPy0300	comX1.1	comX1.1	269685	270236	+	putative competence protein	Best Blastp hit %3D gb|AAD50427.1|AF161700_2 (AF161700) ComX1 [Streptococcus pneumoniae] >gi|5739315|gb|AAD50429.1|AF161701_2 (AF161701) ComX2 [Streptococcus pneumoniae]	gene	gene269	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0300
SPy_0303	SPy0303		SPy_0303	270847	271980	+	putative transposase%2C IS1548	Best Blastp hit %3D emb|CAA74641.1| (Y14270) putative transposase [Streptococcus agalactiae]	gene	gene270	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0303
SPy_0305	SPy0305		SPy_0305	272086	272670	+	hypothetical protein	Best Blastp hit %3D sp|P54452|YQEG_BACSU HYPOTHETICAL 20.1 KD PROTEIN IN NUCB-AROD INTERGENIC REGION >gi|7474689|pir||C69951 conserved hypothetical protein yqeG - Bacillus subtilis >gi|1303787|dbj|BAA12443.1| (D84432) YqeG [Bacillus subtilis] >gi|2635014|emb|CAB14510.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene271	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0305
SPy_0306	SPy0306		SPy_0306	272670	273788	+	hypothetical protein	Best Blastp hit %3D sp|P54453|YQEH_BACSU HYPOTHETICAL 41.0 KD PROTEIN IN NUCB-AROD INTERGENIC REGION >gi|7474690|pir||D69951 conserved hypothetical protein yqeH - Bacillus subtilis >gi|1303788|dbj|BAA12444.1| (D84432) YqeH [Bacillus subtilis] >gi|2635013|emb|CAB14509.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene272	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0306
SPy_0307	SPy0307		SPy_0307	273813	274121	+	hypothetical protein	Best Blastp hit %3D sp|P54454|YQEI_BACSU HYPOTHETICAL 10.8 KD PROTEIN IN AROD-COMER INTERGENIC REGION >gi|7451070|pir||E69951 dihydrodipicolinate reductase homolog yqeI - Bacillus subtilis >gi|1303790|dbj|BAA12446.1| (D84432) YqeI [Bacillus subtilis] >gi|2635011|emb|CAB14507.1| (Z99117) similar to dihydrodipicolinate reductase [Bacillus subtilis]	gene	gene273	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0307
SPy_0308	SPy0308		SPy_0308	274190	274822	+	hypothetical protein	Best Blastp hit %3D sp|P54455|NADD_BACSU PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NICOTINATE MONONUCLEOTIDE ADENYLYLTRANSFERASE) (NAMN ADENYLYLTRANSFERASE) >gi|7430069|pir||F69951 conserved hypothetical protein yqeJ - Bacillus subtilis >gi|1303791|dbj|BAA12447.1| (D84432) YqeJ [Bacillus subtilis] >gi|2635010|emb|CAB14506.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene274	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0308
SPy_0309	SPy0309		SPy_0309	274819	275412	+	hypothetical protein	Best Blastp hit %3D sp|P54456|YQEK_BACSU HYPOTHETICAL 21.3 KD PROTEIN IN AROD-COMER INTERGENIC REGION >gi|7429525|pir||G69951 conserved hypothetical protein yqeK - Bacillus subtilis >gi|1303792|dbj|BAA12448.1| (D84432) YqeK [Bacillus subtilis] >gi|2635009|emb|CAB14505.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene275	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0309
SPy_0310	SPy0310		SPy_0310	275412	275789	+	hypothetical protein	Best Blastp hit %3D sp|P54457|YQEL_BACSU HYPOTHETICAL 13.3 KD PROTEIN IN AROD-COMER INTERGENIC REGION >gi|7444652|pir||H69951 ybeB protein homolog yqeL - Bacillus subtilis >gi|1303793|dbj|BAA12449.1| (D84432) YqeL [Bacillus subtilis] >gi|2635008|emb|CAB14504.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene276	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0310
SPy_0312	SPy0312		SPy_0312	275789	276580	+	hypothetical protein	Best Blastp hit %3D sp|P54458|YQEM_BACSU HYPOTHETICAL 28.3 KD PROTEIN IN AROD-COMER INTERGENIC REGION >gi|7474691|pir||A69952 conserved hypothetical protein yqeM - Bacillus subtilis >gi|1303794|dbj|BAA12450.1| (D84432) YqeM [Bacillus subtilis] >gi|2635007|emb|CAB14503.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis]	gene	gene277	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0312
SPy_0314	SPy0314		SPy_0314	276834	277940	+	hypothetical protein	Best Blastp hit %3D pir||B69875 conserved hypothetical protein ylbM - Bacillus subtilis >gi|2340009|emb|CAB11359.1| (Z98682) YlbM protein [Bacillus subtilis] >gi|2633877|emb|CAB13379.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis]	gene	gene278	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0314
SPy_0315	SPy0315		SPy_0315	278292	278432	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene279	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0315
SPy_0316	SPy0316		SPy_0316	278422	279138	+	hypothetical protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P76351|YEEN_ECOLI HYPOTHETICAL 25.9 KDA PROTEIN IN AMN-CBL INTERGENIC REGION >gi|7448338|pir||A64963 conserved hypothetical protein b1983 - Escherichia coli >gi|1788294|gb|AAC75047.1| (AE000290) orf%2C hypothetical protein [Escherichia coli]	gene	gene280	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0316
SPy_0317	SPy0317		SPy_0317	279341	280183	+	hypothetical protein	Best Blastp hit %3D gb|AAC45332.1| (U97348) basic surface protein [Lactobacillus fermentum]	gene	gene281	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0317
SPy_0319	SPy0319		SPy_0319	280512	281357	+	hypothetical protein	Best Blastp hit %3D emb|CAB59827.1| (AJ012388) hypothetical protein [Lactococcus lactis]	gene	gene282	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0319
SPy_0320	SPy0320		SPy_0320	281607	282671	+	putative ABC transporter (ATP-binding protein)h	Best Blastp hit %3D emb|CAB59828.1| (AJ012388) hypothetical protein [Lactococcus lactis]	gene	gene283	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0320
SPy_0321	SPy0321		SPy_0321	282672	283364	+	putative ABC transporter (permease protein)	Best Blastp hit %3D emb|CAB59829.1| (AJ012388) hypothetical protein [Lactococcus lactis]	gene	gene284	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0321
SPy_0323	SPy0323	braB	braB	283418	284788	-	putative branched-chain amino acid transport protein	Best Blastp hit %3D sp|P54104|BRNQ_LACDL BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM CARRIER PROTEIN (BRANCHED-CHAIN AMINO ACID UPTAKE CARRIER) >gi|2127378|pir||S60180 branched-chain amino acid carrier brnQ - Lactobacillus delbrueckii >gi|732813|emb|CAA88595.1| (Z48676) branched-chain amino acid carrier [Lactobacillus delbrueckii]	gene	gene285	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0323
SPy_0324	SPy0324		SPy_0324	285022	286236	+	putative sodium/dicarboxylate symporter	Best Blastp hit %3D gb|AAF95950.1| (AE004347) sodium/dicarboxylate symporter [Vibrio cholerae]	gene	gene286	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0324
SPy_0326	SPy0326		SPy_0326	286291	286965	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04316.1| (AP001509) unknown conserved protein [Bacillus halodurans]	gene	gene287	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0326
SPy_0327	SPy0327	ntpJ	ntpJ	286975	288366	-	putative V-type Na+ -ATPase subunit J	Best Blastp hit %3D sp|P43440|NTPJ_ENTHR V-TYPE SODIUM ATP SYNTHASE SUBUNIT J (NA(+)-TRANSLOCATING ATPASE SUBUNIT J) >gi|487282|dbj|BAA04279.1| (D17462) Na+ -ATPase subunit J [Enterococcus hirae]	gene	gene288	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0327
SPy_0329	SPy0329	gidB	gidB	288436	289149	-	putative glucose-inhibited division protein	Best Blastp hit %3D sp|Q9K5M8|GIDB_BACHD GLUCOSE INHIBITED DIVISION PROTEIN B >gi|10176685|dbj|BAB07779.1| (AP001520) glucose-inhibited division protein [Bacillus halodurans]	gene	gene289	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0329
SPy_0330	SPy0330	lemA	lemA	289299	289856	+	putative cytoplasmic membrane protein	Best Blastp hit %3D gb|AAG23700.1| (AF017421) LemA-like protein [Streptococcus gordonii]	gene	gene290	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0330
SPy_0331	SPy0331	htpX	htpX	289903	290799	+	putative heat shock protein	Best Blastp hit %3D sp|O30795|HTPX_STRGC PUTATIVE HEAT SHOCK PROTEIN HTPX >gi|11277180|pir||T48855 probable heat shock protein HtpX [imported] - Streptococcus gordonii >gi|2407215|gb|AAB70525.1| (AF017421) putative heat shock protein HtpX [Streptococcus gordonii]	gene	gene291	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0331
SPy_0334	SPy0334		SPy_0334	291030	291566	+	hypothetical protein	Best Blastp hit %3D gb|AAG32547.1| (U12643) YlbN-like hypothetical protein [Streptococcus gordonii]	gene	gene292	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0334
SPy_0336	SPy_0336	csrR	csrR	292525	294027	+	putative sensory transduction histidine kinase	Best Blastp hit %3D gb|AAC64936.1| (AF082668) CsrS [Streptococcus pyogenes]	gene	gene293	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0336
SPy_0338	SPy0338		SPy_0338	294242	294736	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06865.1| (AP001517) unknown conserved protein [Bacillus halodurans]	gene	gene294	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0338
SPy_0339	SPy0339		SPy_0339	294720	295895	+	hypothetical protein	Best Blastp hit %3D dbj|BAA22163.1| (AB006752) ORF1 [Streptococcus pyogenes]	gene	gene295	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0339
SPy_0340	SPy0340	dnaI	dnaI	295896	296798	+	putative primosome component (helicase loader)	Best Blastp hit %3D sp|P06567|DNAI_BACSU PRIMOSOMAL PROTEIN DNAI >gi|279708|pir||IQBS44 primosome component (helicase loader) dnaI - Bacillus subtilis >gi|39881|emb|CAA28633.1| (X04963) ORF 311 (AA 1-311) [Bacillus subtilis] >gi|1769996|emb|CAA99605.1| (Z75208) replication protein [Bacillus subtilis] >gi|2293281|gb|AAC00359.1| (AF008220) DnaI [Bacillus subtilis] >gi|2635363|emb|CAB14858.1| (Z99118) helicase loader [Bacillus subtilis]	gene	gene296	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0340
SPy_0341	SPy0341	pgdA	pgdA	296861	298171	+	putative phosphoglycerate dehydrogenase	Best Blastp hit %3D dbj|BAA88823.1| (AB016077) phosphoglycerate dehydrogenase [Streptococcus mutans]	gene	gene297	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0341
SPy_0342	SPy0342	snf	snf	298378	301476	+	putative SNF helicase	Best Blastp hit %3D emb|CAA67095.1| (X98455) SNF [Bacillus cereus]	gene	gene298	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0342
SPy_0343	SPy0343		SPy_0343	301719	302321	+	hypothetical protein	Best Blastp hit %3D pir||T26413 hypothetical protein Y106G6D.3 - Caenorhabditis elegans >gi|3880676|emb|CAA20976.1| (AL031629) predicted using Genefinder [Caenorhabditis elegans]	gene	gene299	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0343
SPy_0345	SPy0345	murC	murC	302361	303689	+	putative UDP-N-acetyl muramate-alanine ligase	Best Blastp hit %3D sp|P40778|MURC_BACSU UDP-N-ACETYLMURAMATE-ALANINE LIGASE (UDP-N-ACETYLMURAMOYL-L-ALANINE SYNTHETASE) >gi|7437967|pir||C69662 UDP-N-acetylmuramate-alanine ligase (EC 6.3.2.8) murC - Bacillus subtilis >gi|2293216|gb|AAC00294.1| (AF008220) putative UDP-N-acetylmuramate-alanine ligase [Bacillus subtilis] >gi|2635463|emb|CAB14957.1| (Z99119) UDP-N-acetyl muramate-alanine ligase [Bacillus subtilis]	gene	gene300	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0345
SPy_0346	SPy0346		SPy_0346	303735	304217	+	putative arylalkylamine n-acetyltransferase	Best Blastp hit %3D pir||T39187 probable arylalkylamine n-acetyltransferase - fission yeast (Schizosaccharomyces pombe) >gi|6014421|emb|CAB57420.1| (AL121764) putative arylalkylamine n-acetyltransferase [Schizosaccharomyces pombe]	gene	gene301	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0346
SPy_0348	SPy0348		SPy_0348	304329	305903	+	putative aminodeoxychorismate lyase	Best Blastp hit %3D gb|AAF77615.1|AF151720_1 (AF151720) aminodeoxychorismate lyase-like protein [Streptococcus thermophilus]	gene	gene302	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0348
SPy_0349	SPy0349	greA	greA	305928	306458	+	putative transcription elongation factor	Best Blastp hit %3D sp|P80240|GREA_BACSU TRANSCRIPTION ELONGATION FACTOR GREA (TRANSCRIPT CLEAVAGE FACTOR GREA) (GENERAL STRESS PROTEIN 20M) (GSP20M) >gi|7449152|pir||A69637 transcription elongation factor greA - Bacillus subtilis >gi|2635178|emb|CAB14674.1| (Z99117) transcription elongation factor [Bacillus subtilis]	gene	gene303	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0349
SPy_0351	SPy0351		SPy_0351	307081	308004	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04888.1| (AP001511) stage III sporulation protein J [Bacillus halodurans]	gene	gene304	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0351
SPy_0352	SPy0352		SPy_0352	308086	308364	-	putative acylphosphatase	Best Blastp hit %3D sp|O35031|ACYP_BACSU PUTATIVE ACYLPHOSPHATASE (ACYLPHOSPHATE PHOSPHOHYDROLASE) >gi|7436053|pir||B69811 conserved hypothetical protein yflL - Bacillus subtilis >gi|2443234|dbj|BAA22305.1| (D86417) YflL [Bacillus subtilis] >gi|2633088|emb|CAB12593.1| (Z99108) similar to hypothetical proteins [Bacillus subtilis]	gene	gene305	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0352
SPy_0355	SPy0355		SPy_0355	308522	309650	-		IS1548 transposase%3B There is a 10bp deletion confirmed by sequence analysis that results in a frame shift mutation located near the center of this gene.~	gene	gene306	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0355
SPy_0356	SPy0356		SPy_0356	309939	310676	+	putative rRNA methylase	Best Blastp hit %3D dbj|BAB06831.1| (AP001517) rRNA methylase [Bacillus halodurans]	gene	gene307	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0356
SPy_0357	SPy0357		SPy_0357	310715	311215	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06585.1| (AP001516) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene308	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0357
SPy_0358	SPy0358		SPy_0358	311230	311919	+	conserved hypothetical protein (putative membrane spanning protein)	Best Blastp hit %3D gb|AAC18360.1| (AF064763) putative membrane spanning protein [Lactococcus lactis subsp. cremoris]	gene	gene309	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0358
SPy_0359	SPy0359		SPy_0359	312097	312339	+	hypothetical protein	Best Blastp hit %3D gb|AAF30674.1|AE002123_7 (AE002123) conserved hypothetical [Ureaplasma urealyticum]	gene	gene310	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0359
SPy_0361	SPy0361	glr	glr	312517	313311	+	putative glutamate racemase	Best Blastp hit %3D gb|AAF72713.1|AF263927_1 (AF263927) glutamate racemase [Carnobacterium sp. St2]	gene	gene311	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0361
SPy_0362	SPy0362		SPy_0362	313308	314294	+	hypothetical protein	Another possible fusion protein%3B Best Blastp hit %3D pir||C69986 conserved hypothetical protein ysnA - Bacillus subtilis >gi|1770060|emb|CAA99555.1| (Z75208) hypothetical protein [Bacillus subtilis] >gi|2635301|emb|CAB14796.1| (Z99118) similar to hypothetical proteins [Bacillus subtilis]	gene	gene312	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0362
SPy_0363	SPy0363		SPy_0363	314273	314794	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06785.1| (AP001517) unknown conserved protein [Bacillus halodurans]	gene	gene313	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0363
SPy_0364	SPy0364		SPy_0364	314791	315252	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05201.1| (AP001512) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene314	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0364
SPy_0365	SPy0365		SPy_0365	315249	315995	+	hypothetical protein (possible integrase/recombinase)	Best Blastp hit %3D gi|10956351 pXO1-103 [Bacillus anthracis] >gi|7474211|pir||G59103 hypothetical protein pXO1-103 - Bacillus anthracis virulence plasmid pXO1 >gi|4894320|gb|AAD32408.1|AAD32408 (AF065404) pXO1-103 [Bacillus anthracis]	gene	gene315	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0365
SPy_0366	SPy0366		SPy_0366	315995	316696	+	hypothetical protein	Best Blastp hit %3D sp|P35154|YPUG_BACSU HYPOTHETICAL 29.6 KD PROTEIN IN RIBT-DACB INTERGENIC REGION (ORFX7) >gi|629132|pir||S45549 conserved hypothetical protein ypuG - Bacillus subtilis >gi|410131|gb|AAA67487.1| (L09228) ORFX7 [Bacillus subtilis] >gi|2634757|emb|CAB14254.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]	gene	gene316	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0366
SPy_0367	SPy0367		SPy_0367	316693	317244	+	hypothetical protein	Best Blastp hit %3D sp|P35155|YPUH_BACSU HYPOTHETICAL 22.0 KD PROTEIN IN RIBT-DACB INTERGENIC REGION (ORFX8) >gi|629133|pir||S45550 conserved hypothetical protein ypuH - Bacillus subtilis >gi|410132|gb|AAA67488.1| (L09228) ORFX8 [Bacillus subtilis] >gi|2634756|emb|CAB14253.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]	gene	gene317	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0367
SPy_0369	SPy0369		SPy_0369	317367	318089	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05295.1| (AP001512) pseudouridylate synthase [Bacillus halodurans]	gene	gene318	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0369
SPy_0370	SPy0370		SPy_0370	318089	318349	+	hypothetical protein	Best Blastp hit %3D pir||G72251 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4982027|gb|AAD36530.1|AE001797_10 (AE001797) conserved hypothetical protein [Thermotoga maritima]	gene	gene319	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0370
SPy_0371	SPy0371		SPy_0371	318527	319075	+	putative rRNA methylase	Best Blastp hit %3D dbj|BAB04742.1| (AP001510) rRNA methylase [Bacillus halodurans]	gene	gene320	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0371
SPy_0373	SPy0373		SPy_0373	319386	319949	+	hypothetical protein	Best Blastp hit %3D sp|P50726|YPAA_BACSU HYPOTHETICAL 20.5 KD PROTEIN IN SERA-FER INTERGENIC REGION >gi|7475251|pir||E69932 hypothetical protein ypaA - Bacillus subtilis >gi|1146197|gb|AAC83944.1| (L47648) putative [Bacillus subtilis] >gi|2634740|emb|CAB14237.1| (Z99116) ypaA [Bacillus subtilis]	gene	gene321	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0373
SPy_0374	SPy0374		SPy_0374	319951	320604	+	hypothetical protein	Best Blastp hit %3D gb|AAC45388.1| (U81488) putative phosphatidic acid phosphatase [Lactococcus lactis subsp. cremoris]	gene	gene322	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0374
SPy_0376	SPy0376		SPy_0376	320897	321817	+	hypothetical protein	Best Blastp hit %3D pir||D69999 conserved hypothetical protein ytqA - Bacillus subtilis >gi|2293302|gb|AAC00380.1| (AF008220) YtqA [Bacillus subtilis] >gi|2635532|emb|CAB15026.1| (Z99119) similar to hypothetical proteins [Bacillus subtilis]	gene	gene323	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0376
SPy_0377	SPy0377		SPy_0377	321856	322410	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07004.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene324	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0377
SPy_0378	SPy0378	hlyX	hlyX	322543	323877	+	putative hemolysin	Best Blastp hit %3D gb|AAC05772.1| (AF051356) putative hemolysin [Streptococcus mutans]	gene	gene325	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0378
SPy_0379	SPy0379	pflC	pflC	323955	324746	+	putative pyruvate-formate lyase activating enzyme	Best Blastp hit %3D sp|O68575|PFLA_STRMU PYRUVATE FORMATE-LYASE ACTIVATING ENZYME (PFL-ACTIVATING ENZYME) >gi|2952528|gb|AAC05773.1| (AF051356) pyruvate-formate lyase activating enzyme [Streptococcus mutans] >gi|3986294|dbj|BAA34998.1| (AB018417) PFL-activating enzyme [Streptococcus mutans]	gene	gene326	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0379
SPy_0380	SPy0380		SPy_0380	324877	325812	+	putative manganese-dependent inorganic pyrophosphatase (intrageneric coaggregation-relevant adhesin)	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P95765|PPAC_STRGC PROBABLE MANGANESE-DEPENDENT INORGANIC PYROPHOSPHATASE (PYROPHOSPHATE PHOSPHO-HYDROLASE) (PPASE) >gi|1743856|gb|AAB39104.1| (U57759) intrageneric coaggregation-relevant adhesin [Streptococcus gordonii]	gene	gene327	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0380
SPy_0382	SPy0382		SPy_0382	325888	326541	+	conserved streptococcal hypothetical protein	Best Blastp hit %3D gb|AAC05779.1| (AF051356) unknown [Streptococcus mutans]	gene	gene328	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0382
SPy_0383	SPy0383	fhuG	fhuG	326586	327623	-	putative ferrichrome ABC transporter (permease)	Best Blastp hit %3D dbj|BAB04801.1| (AP001510) ferrichrome ABC transporter (permease) [Bacillus halodurans]	gene	gene329	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0383
SPy_0384	SPy0384	fhuB.1	fhuB.1	327584	328615	-	putative ferrichrome ABC transporter (permease)	Best Blastp hit %3D gb|AAD33526.3|AF132117_3 (AF132117) ferrichrome transport permease [Staphylococcus aureus] >gi|9755014|gb|AAF98154.1|AF251216_2 (AF251216) FhuB [Staphylococcus aureus]	gene	gene330	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0384
SPy_0385	SPy0385	fhuD	fhuD	328626	329558	-	ferrichrome ABC transporter (ferrichrome-binding protein)	Best Blastp hit %3D sp|P37580|FHUD_BACSU FERRICHROME-BINDING PROTEIN PRECURSOR >gi|421493|pir||S32930 ferrichrome ABC transporter fhuD precursor - Bacillus subtilis >gi|289272|gb|AAA22424.1| (M87283) ferrichrome-binding protein [Bacillus subtilis] >gi|1070012|emb|CAA63642.1| (X93092) protein-dependent [Bacillus subtilis] >gi|2635846|emb|CAB15338.1| (Z99121) ferrichrome ABC transporter (ferrichrome-binding protein) [Bacillus subtilis] >gi|2832795|emb|CAA11719.1| (AJ223978) ferrichrome binding protein%2C FhuD [Bacillus subtilis]	gene	gene331	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0385
SPy_0386	SPy0386	fhuA	fhuA	329584	330366	-	putative ferrichrome ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAD33527.2|AF132117_4 (AF132117) FhuA [Staphylococcus aureus] >gi|9755013|gb|AAF98153.1|AF251216_1 (AF251216) FhuC [Staphylococcus aureus]	gene	gene332	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0386
SPy_0388	SPy0388	murE	murE	330612	332057	-	putative UDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C6-diaminopimelate ligase	Best Blastp hit %3D sp|O67631|MURE_AQUAE UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMATE-2%2C6-DIAMINOPIMELATE LIGASE (UDP-N-ACETYLMURAMYL-TRIPEPTIDE SYNTHETASE) (MESO-DIAMINOPIMELATE-ADDING ENZYME) (UDP-MURNAC-TRIPEPTIDE SYNTHETASE) >gi|7451747|pir||E70450 UDP-MurNac-tripeptide synthetase - Aquifex aeolicus >gi|2984050|gb|AAC07591.1| (AE000754) UDP-MurNac-tripeptide synthetase [Aquifex aeolicus]	gene	gene333	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0388
SPy_0390	SPy0390		SPy_0390	332145	333779	+	hypothetical protein	Best Blastp hit %3D pir||G69992 spore cortex protein homolog ytgP - Bacillus subtilis >gi|2293198|gb|AAC00276.1| (AF008220) YtgP [Bacillus subtilis] >gi|2635489|emb|CAB14983.1| (Z99119) similar to spore cortex protein [Bacillus subtilis]	gene	gene334	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0390
SPy_0392	SPy0392	upp	upp	333947	334576	+	putative uracil phosphoribosyltransferase	Best Blastp hit %3D sp|P36399|UPP_STRSL URACIL PHOSPHORIBOSYLTRANSFERASE (UMP PYROPHOSPHORYLASE) (UPRTASE) >gi|347998|gb|AAA26890.1| (L07793) uracil phosphoribosyltransferase [Streptococcus salivarius]	gene	gene335	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0392
SPy_0393	SPy0393		SPy_0393	334545	334679	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene336	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0393
SPy_0395	SPy0395	clpP	clpP	334800	335390	+	putative ATP-dependent protease proteolytic subunit	Best Blastp hit %3D sp|P36398|CLPP_STRSL ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT (ENDOPEPTIDASE CLP) >gi|347999|gb|AAA26891.1| (L07793) ATP-dependent protease proteolytic subunit [Streptococcus salivarius]	gene	gene337	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0395
SPy_0397	SPy0397		SPy_0397	335882	336157	+	hypothetical protein	Best Blastp hit %3D pir||D69874 conserved hypothetical protein ylbG - Bacillus subtilis >gi|2340003|emb|CAB11353.1| (Z98682) YlbG protein [Bacillus subtilis] >gi|2633871|emb|CAB13373.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis]	gene	gene338	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0397
SPy_0399	SPy0399	tmk	tmk	336406	337041	+	putative thymidylate kinase	Best Blastp hit %3D dbj|BAB03761.1| (AP001507) thymidylate kinase [Bacillus halodurans]	gene	gene339	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0399
SPy_0400	SPy0400		SPy_0400	337059	337934	+	putative DNA polymerase III delta' subunit	Best Blastp hit %3D dbj|BAB03763.1| (AP001507) DNA polymerase III delta' subunit [Bacillus halodurans]	gene	gene340	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0400
SPy_0401	SPy0401		SPy_0401	337953	338192	+	hypothetical protein	Best Blastp hit %3D dbj|BAB03764.1| (AP001507) signal peptidase-like protein [Bacillus halodurans]	gene	gene341	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0401
SPy_0405	SPy0405		SPy_0405	338597	338920	+	hypothetical protein	Best Blastp hit %3D dbj|BAB03765.1| (AP001507) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene342	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0405
SPy_0406	SPy0406		SPy_0406	338925	339788	+	hypothetical protein	Best Blastp hit %3D dbj|BAB03768.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene343	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0406
SPy_0407	SPy0407		SPy_0407	339815	340207	+	hypothetical protein	Best Blastp hit %3D emb|CAA61744.1| (X89566) cytochrome-c oxidase sbunit I [Nitrobacter winogradskyi]	gene	gene344	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0407
SPy_0408	SPy0408		SPy_0408	340254	340883	-	hypothetical protein	similar to Human CGI-32 protein%3B Best Blastp hit %3D gi|7705728 CGI-32 protein [Homo sapiens] >gi|4680703|gb|AAD27741.1|AF132966_1 (AF132966) CGI-32 protein [Homo sapiens]	gene	gene345	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0408
SPy_0410	SPy0410		SPy_0410	341230	341538	+	putative arsenate reductase	Best Blastp hit %3D dbj|BAB07204.1| (AP001518) arsenate reductase [Bacillus halodurans]	gene	gene346	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0410
SPy_0412	SPy0412	exoA	exoA	341612	342439	-	putative 3'-exo-deoxyribonuclease	Best Blastp hit %3D sp|P37454|EXOA_BACSU EXODEOXYRIBONUCLEASE >gi|2126877|pir||S66012 3'-exo-deoxyribonuclease exoA [similarity] - Bacillus subtilis >gi|467372|dbj|BAA05218.1| (D26185) 3'-exo-deoxyribonuclease [Bacillus subtilis] >gi|2636635|emb|CAB16125.1| (Z99124) 3'-exo-deoxyribonuclease [Bacillus subtilis]	gene	gene347	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0412
SPy_0414	SPy0414	lctO	lctO	342667	343854	+	putative lactate oxidase	Best Blastp hit %3D emb|CAA68903.1| (Y07622) lactate oxidase [Streptococcus iniae]	gene	gene348	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0414
SPy_0416	SPy0416	prtS	prtS	344117	349060	+	putative cell envelope proteinase	Best Blastp hit %3D gb|AAG09771.1|AF243528_1 (AF243528) cell envelope proteinase [Streptococcus thermophilus]	gene	gene349	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0416
SPy_0421	SPy0421		SPy_0421	349831	350538	+	hypothetical protein	Best Blastp hit %3D pir||E69896 hypothetical protein yoaK - Bacillus subtilis >gi|2619025|gb|AAB84449.1| (AF027868) putative permease [Bacillus subtilis] >gi|2634257|emb|CAB13756.1| (Z99114) yoaK [Bacillus subtilis]	gene	gene350	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0421
SPy_0422	SPy0422	metS	metS	350778	352778	+	putative methionyl-tRNA synthetase	Best Blastp hit %3D dbj|BAB03772.1| (AP001507) methionyl-tRNA synthetase [Bacillus halodurans]	gene	gene351	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0422
SPy_0425	SPy0425	nrdF.1	nrdF.1	353273	354286	+	putative ribonucleotide reductase 2	Best Blastp hit %3D sp|P75461|RIR2_MYCPN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE BETA CHAIN (RIBONUCLEOTIDE REDUCTASE) >gi|2146587|pir||S73840 ribonucleotide reductase 2 - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1674208|gb|AAB96162.1| (AE000050) Mycoplasma pneumoniae%2C ribonucleotide reductase 2%3B similar to Swiss-Prot Accession Number P17424%2C from S. typhimurium	gene	gene352	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0425
SPy_0426	SPy0426	nrdI	nrdI	354290	354778	+	putative ribonucleotide reductase (NrdI protein)	Best Blastp hit %3D sp|P47472|NRDI_MYCGE NRDI PROTEIN >gi|1361639|pir||D64225 hypothetical protein MG230 - Mycoplasma genitalium >gi|3844833|gb|AAC71451.1| (U39702) nrdI protein (nrdI) [Mycoplasma genitalium]	gene	gene353	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0426
SPy_0427	SPy0427	nrdE.1	nrdE.1	354745	356925	+	ribonucleoside-diphosphate reductase%2C large chain	Best Blastp hit %3D sp|P78027|RIR1_MYCPN RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE ALPHA CHAIN (RIBONUCLEOTIDE REDUCTASE) >gi|2146586|pir||S73838 ribonucleoside-diphosphate reductase (EC 1.17.4.1) large chain nrdE - Mycoplasma pneumoniae (strain ATCC 29342) >gi|1674206|gb|AAB96160.1| (AE000050) Mycoplasma pneumoniae%2C ribonucleoside-diphosphate reductase%3B similar to Swiss-Prot Accession Number Q08698%2C from S. typhimurium	gene	gene354	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0427
SPy_0428	SPy0428		SPy_0428	357119	357871	-	hypothetical protein	Best Blastp hit %3D sp|P15879|ARC3_CBDP MONO-ADP-RIBOSYLTRANSFERASE C3 PRECURSOR (EXOENZYME C3) >gi|625586|pir||A38912 NAD+-asparagine ADP-ribosyltransferase (EC 2.4.2.-) C3 precursor - Clostridium botulinum phage (strain CST) >gi|296787|emb|CAA41767.1| (X59039) exoenzyme C3 [Clostridium botulinum C phage] >gi|505281|emb|CAA41768.1| (X59040) exoenzyme C3 [Clostridium botulinum D phage]	gene	gene355	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0428
SPy_0430	SPy0430		SPy_0430	358312	358866	+	hypothetical protein	Best Blastp hit %3D gb|AAD29424.1|AF136451_1 (AF136451) fibronectin-binding protein SFS [Streptococcus equi]	gene	gene356	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0430
SPy_0431	SPy0431		SPy_0431	358956	359174	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene357	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0431
SPy_0432	SPy0432		SPy_0432	359140	359391	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene358	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0432
SPy_0433	SPy0433		SPy_0433	359485	360117	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene359	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0433
SPy_0435	SPy0435		SPy_0435	360796	361116	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene360	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0435
SPy_0436	SPy0436	speJ	speJ	361429	362127	-	putative exotoxin (superantigen)	Best Blastp hit %3D sp|P13380|SPEC_STRPY EXOTOXIN TYPE C PRECURSOR (SPE C)	gene	gene361	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0436
SPy_0437	SPy0437		SPy_0437	362375	362989	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene362	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0437
SPy_0439	SPy0439		SPy_0439	363350	363586	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene363	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0439
SPy_0440	SPy0440		SPy_0440	363579	364277	+	putative dehydrogenease / oxidoreductase	Best Blastp hit %3D sp|P39640|YWFD_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PTA-ROCC INTERGENIC REGION >gi|629089|pir||S39737 glucose 1-dehydrogenase homolog ywfD - Bacillus subtilis >gi|414006|emb|CAA51638.1| (X73124) ipa-82d [Bacillus subtilis] >gi|2636308|emb|CAB15799.1| (Z99123) alternate gene name: ipa-82d~similar to glucose 1-dehydrogenase [Bacillus subtilis]	gene	gene364	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0440
SPy_0441	SPy0441		SPy_0441	364353	365312	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06422.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene365	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0441
SPy_0442	SPy0442		SPy_0442	365645	366982	+	putative glycerol-3-phosphate transporter	Best Blastp hit %3D pir||C82495 glycerol-3-phosphate transporter VCA0137 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657525|gb|AAF96050.1| (AE004355) glycerol-3-phosphate transporter [Vibrio cholerae]	gene	gene366	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0442
SPy_0443	SPy0443	gcaD	gcaD	367155	368537	+	putative UDP-N-acetylglucosamine pyrophosphorylase	Best Blastp hit %3D dbj|BAB03784.1| (AP001507) UDP-N-acetylglucosamine pyrophosphorylase [Bacillus halodurans]	gene	gene367	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0443
SPy_0444	SPy0444		SPy_0444	368568	369122	+	hypothetical protein	Best Blastp hit %3D sp|P54570|YQKG_BACSU HYPOTHETICAL 21.0 KDA PROTEIN IN GLNQ-ANSR INTERGENIC REGION >gi|7429371|pir||A69967 conserved hypothetical protein yqkG - Bacillus subtilis >gi|1303984|dbj|BAA12639.1| (D84432) YqkG [Bacillus subtilis] >gi|2634796|emb|CAB14293.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]	gene	gene368	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0444
SPy_0446	SPy0446		SPy_0446	369122	369373	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene369	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0446
SPy_0447	SPy0447	pfs	pfs	369393	370088	+	putative MTA/SAH nucleosidase (5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase)	Best Blastp hit %3D sp|P24247|PFS_ECOLI MTA/SAH NUCLEOSIDASE (P46) [INCLUDES: 5'-METHYLTHIOADENOSINE NUCLEOSIDASE%3B S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE ] >gi|628786|pir||S45227 pfs protein - Escherichia coli >gi|473817|dbj|BAA05606.1| (D26562) 'ORF' [Escherichia coli] >gi|1552737|gb|AAB08589.1| (U70214) similar to purine nucleoside phosphorylase (deoD) [Escherichia coli] >gi|1786354|gb|AAC73270.1| (AE000125) orf%2C hypothetical protein [Escherichia coli] >gi|2981267|gb|AAC38291.1| (U24438) MTA/SAH nucleosidase [Escherichia coli]	gene	gene370	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0447
SPy_0448	SPy0448		SPy_0448	370239	370580	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene371	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0448
SPy_0450	SPy0450		SPy_0450	370681	371328	-	putative metal-dependent transcriptional regulator	Best Blastp hit %3D gb|AAF81675.1|AF232688_4 (AF232688) SloR [Streptococcus mutans]	gene	gene372	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0450
SPy_0453	SPy0453	mtsA	mtsA	371474	372406	+	metal binding protein of ABC transporter (lipoprotein)	Best Blastp hit %3D pir||T48894 lipoprotein mtsA%2C metal binding [validated] - Streptococcus pyogenes (fragment) >gi|5932388|gb|AAD56939.1|AF180521_1 (AF180521) metal binding protein of ABC transporter MtsA [Streptococcus pyogenes]	gene	gene373	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0453
SPy_0454	SPy0454	mtsB	mtsB	372470	373195	+	ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAD56937.1|AF180520_2 (AF180520) ATP-binding protein MtsB [Streptococcus pyogenes]	gene	gene374	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0454
SPy_0456	SPy0456	mtsC	mtsC	373196	374050	+	ABC transporter (permease protein)	Best Blastp hit %3D gb|AAD56938.1|AF180520_3 (AF180520) integral membrane protein MtsC [Streptococcus pyogenes]	gene	gene375	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0456
SPy_0457	SPy0457		SPy_0457	374198	375004	-	putative cyclophilin-type protein	Best Blastp hit %3D pir||T41399 probable cyclophilin-related peptidyl prolyl cis-trans isomerase - fission yeast (Schizosaccharomyces pombe) >gi|3169061|emb|CAA19257.1| (AL023704) putative Cyclophilin-type peptidyl-prolyl cis-trans isomerase protein [Schizosaccharomyces pombe]	gene	gene376	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0457
SPy_0458	SPy0458		SPy_0458	375221	377626	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06114.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene377	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0458
SPy_0459	SPy0459		SPy_0459	377696	378049	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene378	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0459
SPy_0460	SPy0460	rplK	rplK	378293	378718	+	50S ribosomal protein L11	Best Blastp hit %3D sp|Q06796|RL11_BACSU 50S RIBOSOMAL PROTEIN L11 (BL11) >gi|481872|pir||S39860 ribosomal protein L11 (BL11) rplK - Bacillus subtilis >gi|285629|dbj|BAA02561.1| (D13303) ribosomal protein L11 [Bacillus subtilis] >gi|2632369|emb|CAB11878.1| (Z99104) ribosomal protein L11 (BL11) [Bacillus subtilis]	gene	gene379	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0460
SPy_0461	SPy0461	rplA	rplA	378824	379513	+	50S ribosomal protein L1	Best Blastp hit %3D sp|P04447|RL1_BACST 50S RIBOSOMAL PROTEIN L1	gene	gene380	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0461
SPy_0462	SPy0462	pyrH	pyrH	379836	380564	+	putative uridylate kinase (UMP-kinase)	Best Blastp hit %3D emb|CAB38122.1| (AJ011960) UMP-kinase [Lactococcus lactis]	gene	gene381	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0462
SPy_0463	SPy0463	rrf	rrf	380593	381150	+	putative ribosome recycling factor	Best Blastp hit %3D sp|O31203|RRF1_STAAU PROBABLE RIBOSOME RECYCLING FACTOR (RIBOSOME RELEASING FACTOR) (RRF) >gi|3915844|sp|O33276|RRF_STAAU PROBABLE RIBOSOME RECYCLING FACTOR (RIBOSOME RELEASING FACTOR) (RRF) >gi|2645713|gb|AAB87473.1| (AF033018) ribosome recycling factor [Staphylococcus aureus]	gene	gene382	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0463
SPy_0464	SPy0464		SPy_0464	381259	382116	+	hypothetical protein	Best Blastp hit %3D emb|CAA70667.1| (Y09476) YitL [Bacillus subtilis]	gene	gene383	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0464
SPy_0466	SPy0466	msrA.2	msrA.2	382189	382698	+	putative peptide methionine sulfoxide reductase	Best Blastp hit %3D dbj|BAB05167.1| (AP001512) peptide methionine sulfoxide reductase [Bacillus halodurans]	gene	gene384	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0466
SPy_0467	SPy0467		SPy_0467	382695	382910	+	hypothetical protein	Best Blastp hit %3D pir||A69931 hypothetical protein yozE - Bacillus subtilis >gi|2634360|emb|CAB13859.1| (Z99114) yozE [Bacillus subtilis]	gene	gene385	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0467
SPy_0469	SPy0469		SPy_0469	383066	384235	+	putative 42 kDa protein	Best Blastp hit %3D gb|AAA51869.1| (U09352) ORF1%2C putative 42 kDa protein [Streptococcus pyogenes]	gene	gene386	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0469
SPy_0470	SPy0470		SPy_0470	384549	386321	+	67 kDa Myosin-crossreactive streptococcal antigen	Best Blastp hit %3D gb|AAA51870.1| (U09352) 67 kDa Myosin-crossreactive streptococcal antigen [Streptococcus pyogenes]	gene	gene387	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0470
SPy_0471	SPy0471	phoH	phoH	386480	387532	+	phosphate starvation-induced protein	Best Blastp hit %3D sp|P46343|PHOL_BACSU PHOH-LIKE PROTEIN >gi|7446992|pir||E69676 phosphate starvation-induced protein phoH - Bacillus subtilis >gi|1303821|dbj|BAA12477.1| (D84432) YqfE [Bacillus subtilis] >gi|2634980|emb|CAB14476.1| (Z99117) phosphate starvation-induced protein [Bacillus subtilis]	gene	gene388	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0471
SPy_0472	SPy0472		SPy_0472	387578	388153	+	hypothetical protein	Best Blastp hit %3D sp|O86222|Y22A_HAEIN HYPOTHETICAL PROTEIN HI0220.2 >gi|3212185|gb|AAC21888.1| (U32707) H. influenzae predicted coding region HI0220.2 [Haemophilus influenzae Rd]	gene	gene389	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0472
SPy_0473	SPy0473		SPy_0473	388312	388809	+	hypothetical protein	Best Blastp hit %3D gb|AAC38046.1| (AF000954) No definition line found [Streptococcus mutans]	gene	gene390	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0473
SPy_0475	SPy0475	dgk	dgk	388790	389197	+	putative diacylglycerol kinase	Best Blastp hit %3D pir||A36933 diacylglycerol kinase homolog - Streptococcus mutans	gene	gene391	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0475
SPy_0476	SPy0476	era	era	389317	390213	+	GTP-binding protein (GTPase)	Best Blastp hit %3D gb|AAD41632.1|AF072811_1 (AF072811) GTPase Era [Streptococcus pneumoniae]	gene	gene392	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0476
SPy_0477	SPy0477		SPy_0477	390233	390709	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05612.1| (AP001513) unknown conserved protein [Bacillus halodurans]	gene	gene393	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0477
SPy_0478	SPy0478		SPy_0478	391014	391268	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene394	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0478
SPy_0479	SPy0479		SPy_0479	391666	391911	+	conserved hypothetical protein - bacteriocin like peptide associated	Best Blastp hit %3D emb|CAC03521.1| (AJ276410) BlpJ protein [Streptococcus pneumoniae]	gene	gene395	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0479
SPy_0480	SPy0480		SPy_0480	391926	392108	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene396	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0480
SPy_0481	SPy0481		SPy_0481	392433	392985	-		Transposase%3B IS905-like: There are several sequence confirmed mutation within this region inactivating this gene.	gene	gene397	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0481
SPy_0484	SPy0484		SPy_0484	393532	393732	+	conserved hypothetical protein - bacteriocin like peptide associated	Best Blastp hit %3D sp|Q48509|LAFX_LACJO BACTERIOCIN LACTACIN F%2C SUBUNIT LAFX PRECURSOR >gi|149570|gb|AAA16637.1| (M57961) role in the expression of lactacin F%2C part of the laf operon [Lactobacillus sp.]	gene	gene398	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0484
SPy_0486	SPy0486		SPy_0486	394026	394220	+	conserved hypothetical protein - bacteriocin like peptide associated	Best Blastp hit %3D sp|Q48509|LAFX_LACJO BACTERIOCIN LACTACIN F%2C SUBUNIT LAFX PRECURSOR >gi|149570|gb|AAA16637.1| (M57961) role in the expression of lactacin F%2C part of the laf operon [Lactobacillus sp.]	gene	gene399	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0486
SPy_0488	SPy0488		SPy_0488	394713	395708	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene400	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0488
SPy_0489	SPy0489		SPy_0489	395753	396199	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene401	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0489
SPy_0492	SPy0492		SPy_0492	396547	396816	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene402	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0492
SPy_0496	SPy0496	mutR	mutR	397887	398753	+	putative positive transcriptional regulator	Best Blastp hit %3D gb|AAD04237.1| (AF007761) MutR [Streptococcus mutans]	gene	gene403	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0496
SPy_0497	SPy0497	fpg	fpg	398925	399752	+	putative formamidopyrimidine-DNA glycosylase	Best Blastp hit %3D sp|P55045|FPG_STRMU FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE) >gi|475032|dbj|BAA05066.1| (D26071) formamidopyrimidine-DNA glycosylase [Streptococcus mutans]	gene	gene404	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0497
SPy_0498	SPy0498		SPy_0498	399749	400342	+	hypothetical protein	Best Blastp hit %3D sp|O34932|YTAG_BACSU HYPOTHETICAL 22.0 KD PROTEIN IN GAPB-MUTM INTERGENIC REGION >gi|7449771|pir||A69988 conserved hypothetical protein ytaG - Bacillus subtilis >gi|2293275|gb|AAC00353.1| (AF008220) YtaG [Bacillus subtilis] >gi|2635371|emb|CAB14866.1| (Z99118) similar to hypothetical proteins [Bacillus subtilis]	gene	gene405	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0498
SPy_0500	SPy0500		SPy_0500	400532	402034	+	hypothetical protein	Best Blastp hit %3D sp|P39342|YJGR_ECOLI HYPOTHETICAL 54.3 KD PROTEIN IN PEPA-GNTV INTERGENIC REGION (F500) >gi|1361112|pir||S56489 hypothetical 54.3K protein (pepa-gntv intergenic region) - Escherichia coli >gi|537105|gb|AAA97160.1| (U14003) ORF_f500 [Escherichia coli] >gi|1790714|gb|AAC77220.1| (AE000497) orf%2C hypothetical protein [Escherichia coli]	gene	gene406	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0500
SPy_0501	SPy0501		SPy_0501	402156	403349	+	putative multi-drug resistance efflux pump	Best Blastp hit %3D emb|CAA07482.1| (AJ007367) multi-drug resistance efflux pump [Streptococcus pneumoniae]	gene	gene407	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0501
SPy_0502	SPy0502		SPy_0502	403538	403774	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene408	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0502
SPy_0503	SPy0503		SPy_0503	403868	406201	+	putative exoribonuclease R	Best Blastp hit %3D sp|O32231|RNR_BACSU RIBONUCLEASE R (RNASE R) (VACB PROTEIN HOMOLOG) >gi|7443068|pir||G70027 conserved hypothetical protein yvaJ - Bacillus subtilis >gi|2635874|emb|CAB15366.1| (Z99121) similar to hypothetical proteins [Bacillus subtilis]	gene	gene409	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0503
SPy_0504	SPy0504		SPy_0504	406204	406671	+	hypothetical protein	Best Blastp hit %3D gb|AAC23745.1| (AF052209) VacB homolog [Streptococcus pneumoniae]	gene	gene410	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0504
SPy_0505	SPy0505		SPy_0505	406677	407396	+	putative glutamine cyclotransferase	Best Blastp hit %3D pir||E75557 glutamine cyclotransferase - Deinococcus radiodurans (strain R1) >gi|6457779|gb|AAF09704.1|AE001874_1 (AE001874) glutamine cyclotransferase [Deinococcus radiodurans]	gene	gene411	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0505
SPy_0506	SPy0506	pcp	pcp	407512	408159	-	putative pyrrolidone carboxyl peptidase	Best Blastp hit %3D sp|O87765|PCP_LACLC PYRROLIDONE-CARBOXYLATE PEPTIDASE (5-OXOPROLYL-PEPTIDASE) (PYROGLUTAMYL-PEPTIDASE I) (PGP-I) (PYRASE) >gi|3647287|emb|CAA11691.1| (AJ223960) pyrrolidone carboxyl peptidase [Lactococcus lactis subsp. cremoris]	gene	gene412	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0506
SPy_0507	SPy0507		SPy_0507	408209	409135	-	hypothetical protein	Best Blastp hit %3D emb|CAB56669.1| (AL121596) putative membrane protein [Streptomyces coelicolor A3(2)]	gene	gene413	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0507
SPy_0508	SPy0508		SPy_0508	409135	409818	-	hypothetical protein	Best Blastp hit %3D pir||H81401 hydrophobic protein Cj0552 [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968020|emb|CAB75188.1| (AL139075) hydrophobic protein [Campylobacter jejuni]	gene	gene414	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0508
SPy_0510	SPy0510		SPy_0510	410029	410955	-	putative sugar transferase	Best Blastp hit %3D sp|Q45539|CSBB_BACSU CSBB PROTEIN >gi|2126920|pir||JC5173 stress response protein csbB - Bacillus subtilis >gi|1387979|gb|AAB38429.1| (L77099) 44%25 identity over 302 residues with hypothetical protein from Synechocystis sp%2C accession D64006_CD%3B expression induced by environmental stress%3B some similarity to glycosyl transferases%3B two potential membrane-spanning helices [Bacillus subtil> >gi|2633183|emb|CAB12688.1| (Z99108) stress response protein [Bacillus subtilis] >gi|2804544|dbj|BAA24480.1| (D85082) YfhN [Bacillus subtilis]	gene	gene415	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0510
SPy_0511	SPy0511	gloA	gloA	411100	411477	-	putative lactoylglutathione lyase	Best Blastp hit %3D sp|O33393|LGUL_NEIMA LACTOYLGLUTATHIONE LYASE (METHYLGLYOXALASE) (ALDOKETOMUTASE) (GLYOXALASE I) (GLX I) (KETONE-ALDEHYDE MUTASE) (S-D-LACTOYLGLUTATHIONE METHYLGLYOXAL LYASE) >gi|2281946|emb|CAA74673.1| (Y14298) lactoylglutathione lyase [Neisseria meningitidis] >gi|7225560|gb|AAF40783.1| (AE002390) lactoylglutathione lyase [Neisseria meningitidis MC58] >gi|7380768|emb|CAB85359.1| (AL162758) lactoylglutathione lyase [Neisseria meningitidis]	gene	gene416	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0511
SPy_0512	SPy0512		SPy_0512	411488	412153	-	putative NAD(P)H-flavin oxidoreductase	Best Blastp hit %3D pir||E81949 probable NAD(P)H-flavin oxidoreductase NMA1015 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379717|emb|CAB84284.1| (AL162754) putative NAD(P)H-flavin oxidoreductase [Neisseria meningitidis]	gene	gene417	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0512
SPy_0513	SPy0513	pepQ	pepQ	412202	413287	-	putative XAA-PRO dipeptidase%3B X-PRO dipeptidase	Best Blastp hit %3D gb|AAD53120.1|AF176799_2 (AF176799) PepQ [Lactobacillus pentosus]	gene	gene418	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0513
SPy_0514	SPy0514	ccpA	ccpA	413461	414462	+	catabolite control protein A	Best Blastp hit %3D dbj|BAA88121.3| (AB028599) catabolite control protein A [Streptococcus bovis]	gene	gene419	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0514
SPy_0515	SPy0515		SPy_0515	414593	415591	+	putative sugar transferase	Best Blastp hit %3D gb|AAG19110.1| (AE005009) Vng0600c [Halobacterium sp. NRC-1]	gene	gene420	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0515
SPy_0516	SPy0516		SPy_0516	415593	416927	+	putative glucosyl transferase	Best Blastp hit %3D emb|CAA72250.1| (Y11463) ORF5 [Streptococcus pneumoniae]	gene	gene421	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0516
SPy_0517	SPy0517	thrS	thrS	417349	419292	+	putative threonyl-tRNA synthetase 1	Best Blastp hit %3D dbj|BAB06860.1| (AP001517) threonyl-tRNA synthetase 1 [Bacillus halodurans]	gene	gene422	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0517
SPy_0518	SPy0518		SPy_0518	419433	420425	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||G75548 ABC transporter%2C ATP-binding protein - Deinococcus radiodurans (strain R1) >gi|6457873|gb|AAF09790.1|AE001882_8 (AE001882) ABC transporter%2C ATP-binding protein [Deinococcus radiodurans]	gene	gene423	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0518
SPy_0519	SPy0519		SPy_0519	420427	421245	+	hypothetical protein	Best Blastp hit %3D emb|CAB88837.1| (AL353832) putative integral membrane protein. [Streptomyces coelicolor A3(2)]	gene	gene424	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0519
SPy_0521	SPy0521		SPy_0521	421247	422032	+	hypothetical protein	Best Blastp hit %3D emb|CAB88836.1| (AL353832) putative integral membrane transport protein. [Streptomyces coelicolor A3(2)]	gene	gene425	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0521
SPy_0524	SPy0524		SPy_0524	422777	423925	+	putative acetyl-CoA c-acetyltransferase	Best Blastp hit %3D dbj|BAB03328.1| (AB035449) acetyl-CoA c-acetyltransferase [Staphylococcus aureus]	gene	gene426	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0524
SPy_0526	SPy0526		SPy_0526	423882	425129	+	hypothetical protein	Best Blastp hit %3D pir||A69832 probable acid-CoA ligase (EC 6.2.1.-) yhfT [similarity] - Bacillus subtilis >gi|2226256|emb|CAA74543.1| (Y14084) hypothetical protein [Bacillus subtilis] >gi|2633372|emb|CAB12876.1| (Z99109) similar to long-chain fatty-acid-CoA ligase [Bacillus subtilis]	gene	gene427	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0526
SPy_0527	SPy0527		SPy_0527	425224	426219	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene428	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0527
SPy_0528	SPy0528	vicR	vicR	426381	427091	+	two-component response regulator	Best Blastp hit %3D emb|CAB65451.1| (AJ012051) VicR protein [Streptococcus pyogenes]	gene	gene429	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0528
SPy_0529	SPy0529	vicK	vicK	427084	428436	+	two-component sensor histidine kinase	Best Blastp hit %3D emb|CAB65452.1| (AJ012051) VicK protein [Streptococcus pyogenes]	gene	gene430	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0529
SPy_0530	SPy0530	vicX	vicX	428440	429249	+	hypothetical protein	Best Blastp hit %3D emb|CAB65453.1| (AJ012051) VicX protein [Streptococcus pyogenes]	gene	gene431	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0530
SPy_0531	SPy0531	acpA	acpA	429693	430385	+	putative ribonuclease III	Best Blastp hit %3D sp|P51833|RNC_BACSU RIBONUCLEASE III (RNASE III) >gi|7435219|pir||B69693 ribonuclease III (EC 3.1.26.3) - Bacillus subtilis >gi|2633965|emb|CAB13466.1| (Z99112) ribonuclease III [Bacillus subtilis]	gene	gene432	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0531
SPy_0532	SPy0532	smc	smc	430386	433925	+	putative chromosome segregation SMC protein	Best Blastp hit %3D sp|P51834|SMC_BACSU CHROMOSOME PARTITION PROTEIN SMC >gi|7446600|pir||G69708 chromosome segregation SMC protein - Bacillus subtilis >gi|2633966|emb|CAB13467.1| (Z99112) chromosome segregation SMC protein homolog [Bacillus subtilis]	gene	gene433	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0532
SPy_0533	SPy0533		SPy_0533	434178	435029	-	putative positive regulator	Best Blastp hit %3D gb|AAD04237.1| (AF007761) MutR [Streptococcus mutans]	gene	gene434	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0533
SPy_0534	SPy0534	aroE.2	aroE.2	435249	436175	+	putative shikimate 5-dehydrogenase	Best Blastp hit %3D sp|Q58484|AROE_METJA SHIKIMATE 5-DEHYDROGENASE >gi|2129280|pir||C64435 shikimate 5-dehydrogenase (EC 1.1.1.25) - Methanococcus jannaschii >gi|1591730|gb|AAB99086.1| (U67551) shikimate 5-dehydrogenase (aroE) [Methanococcus jannaschii]	gene	gene435	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0534
SPy_0535	SPy0535		SPy_0535	436172	437008	+	hypothetical protein	Best Blastp hit %3D sp|Q58707|YD11_METJA HYPOTHETICAL PROTEIN MJ1311 >gi|2128782|pir||F64463 hypothetical protein MJ1311 - Methanococcus jannaschii >gi|1591950|gb|AAB99318.1| (U67571) conserved hypothetical protein [Methanococcus jannaschii]	gene	gene436	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0535
SPy_0536	SPy0536		SPy_0536	437010	437744	+	hypothetical protein	Best Blastp hit %3D pir||H69002 conserved hypothetical protein MTH1019 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622121|gb|AAB85515.1| (AE000874) conserved protein [Methanobacterium thermoautotrophicum]	gene	gene437	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0536
SPy_0537	SPy0537		SPy_0537	437737	438723	+	hypothetical protein	Best Blastp hit %3D emb|CAB39036.2| (AL034559) ATP-dependent RNA Helicase [Plasmodium falciparum]	gene	gene438	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0537
SPy_0538	SPy0538		SPy_0538	438733	439932	+	putative S-adenosylmethionine synthetase	Best Blastp hit %3D sp|Q58605|METK_METJA S-ADENOSYLMETHIONINE SYNTHETASE (METHIONINE ADENOSYLTRANSFERASE) (ADOMET SYNTHETASE) >gi|2129088|pir||G64450 isoleucine-tRNA ligase 5' region hypothetical protein 401 homolog - Methanococcus jannaschii >gi|1591838|gb|AAB99212.1| (U67562) conserved hypothetical protein [Methanococcus jannaschii]	gene	gene439	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0538
SPy_0539	SPy0539		SPy_0539	439916	440884	+	hypothetical protein	Best Blastp hit %3D gi|10954876 Hypothetical gene [Agrobacterium tumefaciens] >gi|6498229|dbj|BAA87681.1| (AB016260) Hypothetical gene [Agrobacterium tumefaciens]	gene	gene440	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0539
SPy_0540	SPy0540		SPy_0540	440939	441928	+	hypothetical protein	Best Blastp hit %3D pir||F72278 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981783|gb|AAD36304.1|AE001779_6 (AE001779) conserved hypothetical protein [Thermotoga maritima]	gene	gene441	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0540
SPy_0542	SPy0542		SPy_0542	442621	443778	+	putative nucleotide sugar dehydrogenase	Best Blastp hit %3D dbj|BAB07427.1| (AP001519) nucleotide sugar dehydrogenase [Bacillus halodurans]	gene	gene442	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0542
SPy_0543	SPy0543		SPy_0543	443863	445071	+	putative efflux protein	Best Blastp hit %3D pir||H72265 hypothetical protein TM1336 - Thermotoga maritima (strain MSB8) >gi|4981896|gb|AAD36408.1|AE001788_3 (AE001788) permease%2C putative [Thermotoga maritima]	gene	gene443	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0543
SPy_0544	SPy0544		SPy_0544	445174	445383	-	hypothetical protein	Best Blastp hit %3D emb|CAB58317.1| (AL121855) putative transcriptional regulator [Streptomyces coelicolor A3(2)]	gene	gene444	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0544
SPy_0545	SPy0545		SPy_0545	445373	446218	-	hypothetical protein	Best Blastp hit %3D pir||T27066 hypothetical protein Y51A2B.6a - Caenorhabditis elegans >gi|3881031|emb|CAA16394.1| (AL021493) predicted using Genefinder~contains similarity to Pfam domain: PF02206 (Domain of unknown function)%2C Score%3D52.9%2C E-value%3D2.3e-12%2C N%3D1 [Caenorhabditis elegans]	gene	gene445	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0545
SPy_0546	SPy0546		SPy_0546	446303	447031	-	hypothetical protein	Best Blastp hit %3D prf||1703265K cytochrome oxidase I intronic ORF 9 [Podospora anserina]	gene	gene446	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0546
SPy_0547	SPy0547		SPy_0547	447022	447246	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene447	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0547
SPy_0549	SPy0549		SPy_0549	447246	448340	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene448	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0549
SPy_0550	SPy0550		SPy_0550	448359	448688	+	hypothetical protein	Best Blastp hit %3D gb|AAF96232.1| (AE004370) DNA-damage-inducible protein J [Vibrio cholerae]	gene	gene449	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0550
SPy_0552	SPy0552		SPy_0552	448688	448993	+	hypothetical protein	Best Blastp hit %3D pir||G70393 conserved hypothetical protein aq_1088 - Aquifex aeolicus >gi|2983568|gb|AAC07141.1| (AE000722) hypothetical protein [Aquifex aeolicus]	gene	gene450	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0552
SPy_0553	SPy0553		SPy_0553	449012	449284	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene451	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0553
SPy_0555	SPy0555		SPy_0555	449389	449841	+	putative portal protein - phage associated	Best Blastp hit %3D pir||T13514 hypothetical protein 25 - Bacillus phage phi-105 >gi|4126611|dbj|BAA36631.1| (AB016282) ORF25 [bacteriophage phi-105]	gene	gene452	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0555
SPy_0556	SPy0556		SPy_0556	449883	450221	+	hypothetical protein	Best Blastp hit %3D emb|CAC08463.1| (AJ295852) penicillin binding protein 1A [Streptococcus mitis]	gene	gene453	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0556
SPy_0558	SPy0558		SPy_0558	450635	450976	+	hypothetical protein	Best Blastp hit %3D gb|AAF91172.1| (AF199409) merozoite surface protein 1 [Plasmodium vivax]	gene	gene454	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0558
SPy_0559	SPy0559		SPy_0559	451000	451824	+	hypothetical protein	Best Blastp hit %3D pir||D75212 asparagine-tRNA ligase (EC 6.1.1.22) PAB2203 - Pyrococcus abyssi (strain Orsay) >gi|5457656|emb|CAB49147.1| (AJ248283) ASPARAGINYL-TRNA SYNTHETASE (EC 6.1.1.22) (ASPARAGINE-TRNA LIGASE) (ASNRS) [Pyrococcus abyssi]	gene	gene455	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0559
SPy_0560	SPy0560		SPy_0560	451802	453085	+	hypothetical protein	Best Blastp hit %3D sp|P39641|YWFE_BACSU HYPOTHETICAL 52.3 KD PROTEIN IN ROCC-PTA INTERGENIC REGION >gi|629090|pir||S39738 ywfE protein - Bacillus subtilis >gi|414007|emb|CAA51639.1| (X73124) ipa-83d [Bacillus subtilis] >gi|2636307|emb|CAB15798.1| (Z99123) alternate gene name: ipa-83d [Bacillus subtilis]	gene	gene456	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0560
SPy_0561	SPy0561		SPy_0561	452907	454029	+		This gene contains several frameshift and point mutations near the proposed start. However%2C it is possible that the gene is actually transcribed from an internal start site%3B Best Blastp hit %3D sp|Q47511|MCCF_ECOLI MICROCIN C7 SELF-IMMUNITY PROTEIN MCCF >gi|682770|emb|CAA40814.1| (X57583) mccF [Escherichia coli]	gene	gene457	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0561
SPy_0563	SPy0563		SPy_0563	454042	455261	+		This gene contains several frameshift and point mutations near the proposed start. However%2C it is possible that the gene is actually transcribed from an internal start site%3B Best Blastp hit %3D sp|Q9ZK27|SYH_HELPJ HISTIDYL-TRNA SYNTHETASE (HISTIDINE-TRNA LIGASE) (HISRS) >gi|7437812|pir||D71847 histidine-tRNA ligase (EC 6.1.1.21) - Helicobacter pylori (strain J99) >gi|4155714|gb|AAD06696.1| (AE001539) HISTIDYL-TRNA SYNTHETASE [Helicobacter pylori J99]	gene	gene458	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0563
SPy_0565	SPy0565	tnpA	tnpA	455714	456750	-		This gene contains several frameshift and point mutations near the proposed start.%3B Best Blastp hit %3D gb|AAB01067.1| (U23813) transposase [Lactococcus lactis]	gene	gene459	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0565
SPy_0567	SPy0567		SPy_0567	457055	457852	+	hypothetical protein	Best Blastp hit %3D sp|P75809|YBJI_ECOLI PROTEIN YBJI	gene	gene460	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0567
SPy_0568	SPy0568		SPy_0568	457856	458680	+	hypothetical protein	Best Blastp hit %3D gb|AAA62048.1| (L10328) f270 [Escherichia coli]	gene	gene461	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0568
SPy_0569	SPy0569	ftsY	ftsY	458680	460230	+	putative signal recognition particle (docking protein)	Best Blastp hit %3D emb|CAB13468.1| (Z99112) signal recognition particle (docking protein) [Bacillus subtilis]	gene	gene462	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0569
SPy_0570	SPy0570		SPy_0570	460284	461651	-	putative drug resistance protein	Best Blastp hit %3D pir||E69652 lincomycin-resistance protein lmrB - Bacillus subtilis >gi|2415718|dbj|BAA22228.1| (AB000617) LmrB [Bacillus subtilis] >gi|2632553|emb|CAB12061.1| (Z99105) drug-export protein [Bacillus subtilis]	gene	gene463	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0570
SPy_0571	SPy0571	licT	licT	461979	462821	+	putative transcription antiterminator	Best Blastp hit %3D sp|P39805|LICT_BACSU TRANSCRIPTION ANTITERMINATOR LICT >gi|628995|pir||S47216 transcription antiterminator licT - Bacillus subtilis >gi|534045|emb|CAA82194.1| (Z28340) antiterminator [Bacillus subtilis]	gene	gene464	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0571
SPy_0572	SPy0572		SPy_0572	462823	464685	+	beta-glucoside permease IIABC component	Best Blastp hit %3D sp|P40739|PTBA_BACSU PTS SYSTEM%2C BETA-GLUCOSIDES-SPECIFIC IIABC COMPONENT (EIIABC-BGL) (BETA-GLUCOSIDES-PERMEASE IIABC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C ABC COMPONENT) (EII-BGL) >gi|2126898|pir||I40406 beta-glucoside permease - Bacillus subtilis >gi|505576|emb|CAA84286.1| (Z34526) beta-glucoside permease [Bacillus subtilis]	gene	gene465	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0572
SPy_0574	SPy0574	bglA	bglA	464704	466128	+	beta-glucosidase	Best Blastp hit %3D gb|AAF89979.1|AF206272_5 (AF206272) beta-glucosidase [Streptococcus mutans]	gene	gene466	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0574
SPy_0575	SPy0575		SPy_0575	466227	467042	-	hypothetical protein	Best Blastp hit %3D gb|AAF09593.1| (AF142677) unknown [Bacillus megaterium]	gene	gene467	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0575
SPy_0576	SPy0576		SPy_0576	467042	467944	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05237.1| (AP001512) unknown conserved protein [Bacillus halodurans]	gene	gene468	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0576
SPy_0577	SPy0577		SPy_0577	468092	468247	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene470	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0577
SPy_0578	SPy0578		SPy_0578	468078	468275	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene469	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0578
SPy_0580	SPy0580		SPy_0580	468481	470613	+	hypothetical protein	Best Blastp hit %3D dbj|BAB04250.1| (AP001508) unknown conserved protein [Bacillus halodurans]	gene	gene471	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0580
SPy_0581	SPy0581		SPy_0581	470600	471037	+	hypothetical protein	Best Blastp hit %3D dbj|BAA90855.1| (AB031213) YdcK [Bacillus halodurans] >gi|10173145|dbj|BAB04251.1| (AP001508) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene472	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0581
SPy_0583	SPy0583		SPy_0583	471101	471373	+	hypothetical protein	Best Blastp hit %3D pir||B72287 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981705|gb|AAD36232.1|AE001773_1 (AE001773) conserved hypothetical protein [Thermotoga maritima]	gene	gene473	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0583
SPy_0584	SPy0584	ptsK	ptsK	471738	472670	+	Hpr kinase/phosphatase	Best Blastp hit %3D dbj|BAA77782.1| (AB027460) Hpr kinase [Streptococcus bovis]	gene	gene474	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0584
SPy_0585	SPy0585	lgt	lgt	472667	473446	+	putative prolipoprotein diacylglycerol transferase	Best Blastp hit %3D sp|P72482|LGT_STRMU PROLIPOPROTEIN DIACYLGLYCERYL TRANSFERASE >gi|7433975|pir||T11569 prolipoprotein diacylglyceryl transferase (EC 2.4.99.-) - Streptococcus mutans >gi|4583534|gb|AAC80171.3| (U75480) putative prolipoprotein diacylglycerol transferase [Streptococcus mutans]	gene	gene475	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0585
SPy_0587	SPy0587		SPy_0587	473468	473875	+	hypothetical protein	Best Blastp hit %3D pir||T11570 hypothetical protein 1 - Streptococcus mutans >gi|4321110|gb|AAD15621.1| (U75480) unknown [Streptococcus mutans]	gene	gene476	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0587
SPy_0588	SPy0588		SPy_0588	473868	474296	+	hypothetical protein	Best Blastp hit %3D pir||T11571 hypothetical protein 2 - Streptococcus mutans >gi|4321111|gb|AAD15622.1| (U75480) unknown [Streptococcus mutans]	gene	gene477	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0588
SPy_0589	SPy0589		SPy_0589	474456	474740	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene478	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0589
SPy_0590	SPy0590		SPy_0590	474939	475865	+	putative protease	Best Blastp hit %3D pir||G69979 proteinase homolog yrrN - Bacillus subtilis >gi|2635181|emb|CAB14677.1| (Z99117) similar to protease [Bacillus subtilis]	gene	gene479	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0590
SPy_0591	SPy0591		SPy_0591	475956	477242	+	putative protease	Best Blastp hit %3D dbj|BAB04993.1| (AP001511) protease [Bacillus halodurans]	gene	gene480	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0591
SPy_0593	SPy0593		SPy_0593	477452	477664	+	hypothetical protein	Best Blastp hit %3D sp|O83371|Y352_TREPA HYPOTHETICAL PROTEIN TP0352 >gi|7519496|pir||F71333 hypothetical protein TP0352 - syphilis spirochete >gi|3322644|gb|AAC65352.1| (AE001215) T. pallidum predicted coding region TP0352 [Treponema pallidum]	gene	gene481	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0593
SPy_0595	SPy0595	lysS	lysS	478037	479530	-	putative lysyl-tRNA synthetase	Best Blastp hit %3D sp|Q53638|SYK_STAAU LYSYL-TRNA SYNTHETASE (LYSINE-TRNA LIGASE) (LYSRS) >gi|567884|gb|AAA53114.1| (L36472) lysyl-tRNA synthetase [Staphylococcus aureus]	gene	gene482	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0595
SPy_0596	SPy0596		SPy_0596	479704	480606	+	hypothetical protein	Best Blastp hit %3D pir||E69814 conserved hypothetical protein yfnB - Bacillus subtilis >gi|2116760|dbj|BAA20111.1| (D86418) YfnB [Bacillus subtilis] >gi|2633046|emb|CAB12552.1| (Z99107) similar to hypothetical proteins [Bacillus subtilis] >gi|2633057|emb|CAB12562.1| (Z99108) similar to hypothetical proteins [Bacillus subtilis]	gene	gene483	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0596
SPy_0598	SPy0598		SPy_0598	480714	481337	-	putative phosphoglycerate mutase	Best Blastp hit %3D pir||A75400 probable phosphoglycerate mutase - Deinococcus radiodurans (strain R1) >gi|6459150|gb|AAF10964.1|AE001985_1 (AE001985) phosphoglycerate mutase%2C putative [Deinococcus radiodurans]	gene	gene484	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0598
SPy_0599	SPy0599		SPy_0599	481678	482157	-	putative transcription regulator	Best Blastp hit %3D pir||D69849 transcription regulation homolog yjdI - Bacillus subtilis >gi|2633560|emb|CAB13063.1| (Z99110) similar to transcription regulation [Bacillus subtilis]	gene	gene485	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0599
SPy_0600	SPy0600		SPy_0600	482248	482811	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04549.1| (AP001510) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene486	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0600
SPy_0601	SPy0601		SPy_0601	483080	483928	-	putative endolysin%2C phage associated	Best Blastp hit %3D pir||JC5911 lysin - Lactobacillus phage phi-gle	gene	gene487	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0601
SPy_0603	SPy0603		SPy_0603	484253	484756	+	hypothetical protein	Best Blastp hit %3D gb|AAF94735.1| (AE004235) NADH dehydrogenase%2C putative [Vibrio cholerae]	gene	gene488	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0603
SPy_0604	SPy0604		SPy_0604	484740	485126	+	hypothetical protein	Best Blastp hit %3D sp|P38537|SLAP_BACSH SURFACE-LAYER 125 KD PROTEIN PRECURSOR >gi|98190|pir||A33856 surface-layer 125K protein precursor - Bacillus sphaericus >gi|556012|gb|AAA50256.1| (M28361) surface layer protein [Bacillus sphaericus]	gene	gene489	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0604
SPy_0605	SPy0605	bsaA	bsaA	485172	485651	-	putative glutathione peroxidase	Best Blastp hit %3D dbj|BAA75395.1| (AB013377) BsaA [Bacillus halodurans] >gi|10175451|dbj|BAB06549.1| (AP001516) glutathione peroxidase [Bacillus halodurans]	gene	gene490	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0605
SPy_0606	SPy0606	pepF	pepF	485644	487443	-	putative oligopeptidase	Best Blastp hit %3D pir||T44581 thimet oligopeptidase (EC 3.4.24.15) [imported] - Bacillus licheniformis >gi|1651216|dbj|BAA13561.1| (D88209) Pz-peptidase [Bacillus licheniformis]	gene	gene491	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0606
SPy_0608	SPy0608	ppc	ppc	487638	490400	+	putative phosphoenolpyruvate carboxylase	Best Blastp hit %3D sp|O32483|CAPP_RHOPA PHOSPHOENOLPYRUVATE CARBOXYLASE (PEPCASE) (PEPC) >gi|2339975|dbj|BAA21835.1| (D89668) phosphoenolpyruvate carboxylase [Rhodopseudomonas palustris]	gene	gene492	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0608
SPy_0609	SPy0609	ftsW	ftsW	490540	491844	+	putative cell division protein	Best Blastp hit %3D sp|Q47866|FTSW_ENTHR PROBABLE CELL DIVISION PROTEIN FTSW >gi|1469784|gb|AAB39929.1| (U58049) putative cell division protein ftsW [Enterococcus hirae]	gene	gene493	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0609
SPy_0611	SPy0611	tufA	tufA	492198	493394	+	putative translation elongation factor EF-Tu	Best Blastp hit %3D sp|P33170|EFTU_STROR ELONGATION FACTOR TU (EF-TU) >gi|320486|pir||F60663 translation elongation factor EF-Tu - Streptococcus oralis	gene	gene494	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0611
SPy_0613	SPy0613	tpi	tpi	493635	494393	+	putative triosephosphate isomerase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|O32757|TPIS_LACDE TRIOSEPHOSPHATE ISOMERASE (TIM) >gi|7437339|pir||T09635 triose-phosphate isomerase (EC 5.3.1.1) - Lactobacillus delbrueckii >gi|2624193|emb|CAA04016.1| (AJ000339) triosephosphate isomerase [Lactobacillus delbrueckii]	gene	gene495	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0613
SPy_0615	SPy0615	murN	murN	494492	495727	-	putative peptidoglycan branched peptide synthesis protein%2C alanine adding enzyme	Best Blastp hit %3D emb|CAB89121.1| (AJ277485) beta-lactam resistance factor [Streptococcus pneumoniae]	gene	gene496	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0615
SPy_0616	SPy0616	murM	murM	495714	496940	-	putative peptidoglycan branched peptide synthesis protein%2C serine/alanine adding enzyme	Best Blastp hit %3D emb|CAB89535.1| (AJ250764) MurM protein [Streptococcus pneumoniae]	gene	gene497	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0616
SPy_0617	SPy0617		SPy_0617	496940	497749	-	hypothetical protein	Best Blastp hit %3D sp|P09997|YIDA_ECOLI HYPOTHETICAL 29.7 KD PROTEIN IN IBPA-GYRB INTERGENIC REGION >gi|7429213|pir||QQECGB hypothetical 29.7K protein%2C ibpA-gyrB intergenic region - Escherichia coli (strain K-12) >gi|2367265|gb|AAC76720.1| (AE000446) orf%2C hypothetical protein [Escherichia coli]	gene	gene498	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0617
SPy_0619	SPy0619		SPy_0619	497900	498133	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene499	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0619
SPy_0621	SPy0621		SPy_0621	498205	499506	-	hypothetical protein	Best Blastp hit %3D sp|P39651|YWFO_BACSU HYPOTHETICAL 51.0 KD PROTEIN IN PTA 3'REGION >gi|7450837|pir||G70056 ywfO protein - Bacillus subtilis >gi|1561567|emb|CAB02494.1| (Z80355) Unknown [Bacillus subtilis] >gi|2636296|emb|CAB15787.1| (Z99123) alternate gene name: ipa-93d~similar to hypothetical proteins [Bacillus subtilis]	gene	gene500	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0621
SPy_0622	SPy0622		SPy_0622	499588	499974	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene501	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0622
SPy_0623	SPy0623	pacL	pacL	500205	502886	+	putative calcium-transporting ATPase	Best Blastp hit %3D pir||H69877 calcium-transporting ATPase homolog yloB - Bacillus subtilis >gi|2337795|emb|CAA74269.1| (Y13937) putative PacL protein [Bacillus subtilis] >gi|2633938|emb|CAB13439.1| (Z99112) similar to calcium-transporting ATPase [Bacillus subtilis]	gene	gene502	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0623
SPy_0627	SPy0627	regR	regR	502970	503965	-	putative transcriptional regulator (LacI family)	Best Blastp hit %3D sp|P50844|KDGR_BACSU KDG OPERON REPRESSOR >gi|7442871|pir||B69648 transcription repressor of pectin utilization operon kdgR - Bacillus subtilis >gi|1146188|gb|AAB38478.1| (L47838) repressor protein [Bacillus subtilis] >gi|2634631|emb|CAB14129.1| (Z99115) transcriptional regulator (LacI family) [Bacillus subtilis]	gene	gene503	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0627
SPy_0628	SPy0628		SPy_0628	504029	505936	-	hypothetical protein	Best Blastp hit %3D pir||T36084 hypothetical protein SCE134.02c - Streptomyces coelicolor >gi|4678627|emb|CAB41200.1| (AL049661) hypothetical protein [Streptomyces coelicolor A3(2)]	gene	gene504	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0628
SPy_0629	SPy0629	agaD	agaD	506023	506844	-	putative PTS dependent galactosamine IID component	Best Blastp hit %3D sp|P42911|PTPD_ECOLI PTS SYSTEM%2C N-ACETYLGALACTOSAMINE-SPECIFIC IID COMPONENT (EIID-AGA) (N-ACETYLGALACTOSAMINE-PERMEASE IID COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C D COMPONENT) >gi|7434458|pir||H65103 pts system%2C n-acetylgalactosamine-specific IID component - Escherichia coli (strain K-12) >gi|1789529|gb|AAC76174.1| (AE000395) PTS system%2C N-acetylglucosamine enzyme IID component 1 [Escherichia coli] >gi|8895756|gb|AAF81092.1|AF228498_12 (AF228498) AgaD [Escherichia coli]	gene	gene505	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0629
SPy_0630	SPy0630	agaW	agaW	506831	507613	-	putative PTS dependent N-acetyl-galactosamine-IIC component	Best Blastp hit %3D gb|AAF81084.1|AF228498_4 (AF228498) AgaW [Escherichia coli]	gene	gene506	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0630
SPy_0631	SPy0631	agaV	agaV	507632	508120	-	putative PTS dependent N-acetyl-galactosamine-IIB component	Best Blastp hit %3D sp|P42904|PTPV_ECOLI PTS SYSTEM%2C N-ACETYLGALACTOSAMINE-SPECIFIC IIB COMPONENT 2 (EIIB-AGA') (N-ACETYLGALACTOSAMINE-PERMEASE IIB COMPONENT 2) (PHOSPHOTRANSFERASE ENZYME II%2C B COMPONENT 2)	gene	gene507	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0631
SPy_0632	SPy0632	ugl	ugl	508156	509355	-	putative unsaturated glucuronyl hydrolase	Best Blastp hit %3D dbj|BAB05773.1| (AP001514) unsaturated glucuronyl hydrolase [Bacillus halodurans]	gene	gene508	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0632
SPy_0634	SPy0634	agaF	agaF	509355	509792	-	putative PTS dependent N-acetyl-galactosamine- and galactosamine IIA component	Best Blastp hit %3D gb|AAC44682.1| (U65015) PTS permease for mannose subunit IIIMan N terminal domain [Vibrio furnissii]	gene	gene509	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0634
SPy_0636	SPy0636	idnO	idnO	510128	510922	+	putative 5-keto-D-gluconate 5-reductase	Best Blastp hit %3D sp|P39345|IDNO_ECOLI GLUCONATE 5-DEHYDROGENASE (5-KETO-D-GLUCONATE 5-REDUCTASE) >gi|1361067|pir||S56492 hypothetical 27.6K protein (pepa-gntv intergenic region) - Escherichia coli >gi|537108|gb|AAA97163.1| (U14003) ORF_f254 [Escherichia coli] >gi|1790717|gb|AAC77223.1| (AE000497) 5-keto-D-gluconate 5-reductase [Escherichia coli]	gene	gene510	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0636
SPy_0637	SPy0637		SPy_0637	510947	511588	+	sugar-phosphate isomerase	Best Blastp hit %3D pir||H72296 sugar-phosphate isomerase - Thermotoga maritima (strain MSB8) >gi|4981625|gb|AAD36157.1|AE001768_6 (AE001768) sugar-phosphate isomerase [Thermotoga maritima]	gene	gene511	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0637
SPy_0638	SPy0638	kdgK	kdgK	511617	512618	+	putative 2-keto-3-deoxygluconate kinase	Best Blastp hit %3D pir||G72422 2-keto-3-deoxygluconate kinase - Thermotoga maritima (strain MSB8) >gi|4980554|gb|AAD35161.1|AE001693_7 (AE001693) 2-keto-3-deoxygluconate kinase [Thermotoga maritima]	gene	gene512	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0638
SPy_0639	SPy0639	kgdA	kgdA	512623	513258	+	putative 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase	Best Blastp hit %3D pir||F72422 KHG-KDPG bifunctional aldolase TM0066 [similarity] - Thermotoga maritima (strain MSB8) >gi|4980553|gb|AAD35160.1|AE001693_6 (AE001693) 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Thermotoga maritima]	gene	gene513	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0639
SPy_0640	SPy0640		SPy_0640	513548	514204	+	hypothetical protein	Best Blastp hit %3D sp|O33513|CBBY_RHOCA CBBY PROTEIN >gi|7435099|pir||T10510 cbbY protein - Rhodobacter capsulatus >gi|2564976|gb|AAB82052.1| (U23145) CbbY [Rhodobacter capsulatus]	gene	gene514	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0640
SPy_0642	SPy0642		SPy_0642	514845	516020	+	hypothetical protein	Best Blastp hit %3D pir||E69820 conserved hypothetical protein yhbA - Bacillus subtilis >gi|1903044|emb|CAB07527.1| (Z93102) hypothetical 48.5 kd protein [Bacillus subtilis] >gi|2633214|emb|CAB12719.1| (Z99108) alternate gene name: ygaP~similar to hypothetical proteins [Bacillus subtilis]	gene	gene515	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0642
SPy_0643	SPy0643	prfB	prfB	516174	517187	+	putative peptide chain release factor 2	There is an ATG start codon with a strong RBS consensus site located in an alternate reading frame upstream of the predicted start codon. The alternate start codon would put this ORF in good agreement with the peptide chain release factor 2 of Bacillus subtilis. No evidence of sequencing error was indicated in this region%3B Best Blastp hit %3D sp|P28367|RF2_BACSU PEPTIDE CHAIN RELEASE FACTOR 2 (RF-2) >gi|7428985|pir||JN0146 translation releasing factor RF-2 - Bacillus subtilis >gi|2331287|gb|AAC97534.1| (AF013188) release factor 2 [Bacillus subtilis] >gi|2618874|gb|AAC67303.1| (AF017113) putative peptide chain release factor RF-2 [Bacillus subtilis] >gi|2636055|emb|CAB15546.1| (Z99122) peptide chain release factor 2 [Bacillus subtilis]	gene	gene516	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0643
SPy_0644	SPy0644	ftsE	ftsE	517206	517898	+	putative cell-division ATP-binding protein	Best Blastp hit %3D pir||D69627 cell-division ATP-binding protein ftsE - Bacillus subtilis >gi|2618833|gb|AAC67262.1| (AF017113) cell division ATP-binding protein [Bacillus subtilis] >gi|2636052|emb|CAB15543.1| (Z99122) cell-division ATP-binding protein [Bacillus subtilis]	gene	gene517	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0644
SPy_0645	SPy0645	ftsX	ftsX	517882	518820	+	putative cell-division protein	Best Blastp hit %3D sp|O34876|FTSX_BACSU CELL DIVISION PROTEIN FTSX HOMOLOG >gi|7474494|pir||G69627 cell-division protein ftsX - Bacillus subtilis >gi|2618835|gb|AAC67264.1| (AF017113) cell division protein [Bacillus subtilis] >gi|2636051|emb|CAB15542.1| (Z99122) cell-division protein [Bacillus subtilis]	gene	gene518	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0645
SPy_0646	SPy0646		SPy_0646	519130	519828	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06539.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene519	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0646
SPy_0647	SPy0647		SPy_0647	519996	520757	+		acetion reductase (budC)	gene	gene520	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0647
SPy_0649	SPy0649	dinG	dinG	520868	523369	+	putative ATP-dependent DNA helicase	Best Blastp hit %3D dbj|BAB05410.1| (AP001512) ATP-dependent DNA helicase [Bacillus halodurans]	gene	gene521	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0649
SPy_0650	SPy0650	aspC	aspC	523704	524897	+	putative aspartate aminotransferase	Best Blastp hit %3D gb|AAF12702.1|AF035157_1 (AF035157) aspartate aminotransferase [Lactococcus lactis]	gene	gene522	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0650
SPy_0651	SPy0651	asnS	asnS	524918	526264	+	putative asparaginyl-tRNA synthetase	Best Blastp hit %3D dbj|BAB05415.1| (AP001512) asparaginyl-tRNA synthetase [Bacillus halodurans]	gene	gene523	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0651
SPy_0652	SPy0652		SPy_0652	526678	527568	+	hypothetical protein	Best Blastp hit %3D sp|O06973|YVCJ_BACSU HYPOTHETICAL 33.9 KD PROTEIN IN CRH-TRXB INTERGENIC REGION >gi|7430187|pir||H70031 conserved hypothetical protein yvcJ - Bacillus subtilis >gi|1945650|emb|CAB08057.1| (Z94043) hypothetical protein [Bacillus subtilis] >gi|2635990|emb|CAB15482.1| (Z99121) similar to hypothetical proteins [Bacillus subtilis]	gene	gene524	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0652
SPy_0653	SPy0653		SPy_0653	527565	528542	+	hypothetical protein	Best Blastp hit %3D emb|CAB96620.1| (AJ400630) hypothetical protein [Streptococcus pneumoniae bacteriophage MM1] >gi|8953589|emb|CAB96623.1| (AJ400631) hypothetical protein [Streptococcus pneumoniae]	gene	gene525	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0653
SPy_0654	SPy0654		SPy_0654	528539	529450	+	hypothetical protein	Best Blastp hit %3D emb|CAB96619.1| (AJ400630) hypothetical protein [Streptococcus pneumoniae bacteriophage MM1] >gi|8953588|emb|CAB96622.1| (AJ400631) hypothetical protein [Streptococcus pneumoniae]	gene	gene526	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0654
SPy_0655	SPy0655	int1	int1	529627	531042	-	putative integrase%3B bacteriophage 370.1	Best Blastp hit %3D gb|AAD26564.1|AF124258_1 (AF124258) site-specific integrase [bacteriophage phi-FC1]	gene	gene527	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0655
SPy_0656	SPy0656		SPy_0656	531163	531528	-	hypothetical protein	Best Blastp hit %3D pir||T13290 hypothetical protein 2 - Streptococcus phage phi-O1205 >gi|2444082|gb|AAC79518.1| (U88974) ORF2 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene528	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0656
SPy_0657	SPy0657		SPy_0657	531555	532316	-	putative cI-like repressor%2C phage associated	Best Blastp hit %3D gi|9632965 orf127 gp [Streptococcus thermophilus bacteriophage Sfi21] >gi|2292761|emb|CAA64934.1| (X95646) cI-like repressor [Streptococcus thermophilus bacteriophage Sfi21] >gi|5524046|gb|AAD44098.1|AF115103_28 (AF115103) orf127 gp [Streptococcus thermophilus bacteriophage Sfi21]	gene	gene529	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0657
SPy_0658	SPy0658		SPy_0658	532500	532730	+	putative Cro-like protein%2C phage associated	Best Blastp hit %3D emb|CAA73340.1| (Y12813) hypothetical protein [Lactobacillus casei bacteriophage A2] >gi|6599315|emb|CAB63661.1| (AJ251789) Cro protein [Lactobacillus casei bacteriophage A2]	gene	gene530	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0658
SPy_0659	SPy0659		SPy_0659	532799	532936	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene531	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0659
SPy_0660	SPy0660		SPy_0660	532938	533063	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene532	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0660
SPy_0661	SPy0661		SPy_0661	533060	533287	+	hypothetical protein	Best Blastp hit %3D emb|CAB73573.1| (AL139079) putative oxidoreductase [Campylobacter jejuni]	gene	gene533	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0661
SPy_0663	SPy0663		SPy_0663	533287	534606	+	hypothetical protein	Best Blastp hit %3D pir||A64465 hypothetical protein MJ1322 - Methanococcus jannaschii >gi|1591962|gb|AAB99331.1| (U67572) purine NTPase [Methanococcus jannaschii]	gene	gene534	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0663
SPy_0664	SPy0664		SPy_0664	534621	535712	+	hypothetical protein	Best Blastp hit %3D gi|9632922 orf233 gp [Streptococcus thermophilus bacteriophage Sfi19] >gi|4049993|gb|AAC97920.1| (AF077306) gp233 [Streptococcus thermophilus bacteriophage Sfi19] >gi|5524017|gb|AAD44070.1|AF115102_29 (AF115102) orf233 gp [Streptococcus thermophilus bacteriophage Sfi19] >gi|7523582|gb|AAF63084.1|AF158601_12 (AF158601) gp233 [Streptococcus thermophilus bacteriophage SFi18]	gene	gene535	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0664
SPy_0665	SPy0665		SPy_0665	535752	536174	+	hypothetical protein	Best Blastp hit %3D pir||T15692 hypothetical protein C28G1.4 - Caenorhabditis elegans >gi|1086705|gb|AAA82353.1| (U41026) Similar to zinc finger [Caenorhabditis elegans]	gene	gene536	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0665
SPy_0666	SPy0666		SPy_0666	536176	536910	+	hypothetical protein	Best Blastp hit %3D emb|CAB82814.1| (AL162459) putative protein [Arabidopsis thaliana]	gene	gene537	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0666
SPy_0667	SPy0667		SPy_0667	536932	537567	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene538	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0667
SPy_0669	SPy0669		SPy_0669	537567	539150	+	putative DEAD box family helicase%2C phage associated	Best Blastp hit %3D pir||T40328 DEAD box family helicase - fission yeast (Schizosaccharomyces pombe) >gi|2995347|emb|CAA18301.1| (AL022244) DEAD box family helicase [Schizosaccharomyces pombe]	gene	gene539	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0669
SPy_0670	SPy0670		SPy_0670	539160	539789	+	hypothetical protein	Best Blastp hit %3D gi|9635666 Orf78 [Pseudomonas phage D3] >gi|8895176|gb|AAF80834.1| (AF165214) Orf78 [Pseudomonas phage D3]	gene	gene540	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0670
SPy_0671	SPy0671		SPy_0671	539779	542052	+	hypothetical protein	Best Blastp hit %3D emb|CAB75598.1| (AJ271879) putative DNA helicase [uncultured eubacterium]	gene	gene541	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0671
SPy_0672	SPy0672		SPy_0672	542330	542548	+	hypothetical protein	Best Blastp hit %3D emb|CAC13148.1| (AJ400623) MADS box protein [Gerbera hybrida]	gene	gene542	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0672
SPy_0673	SPy0673		SPy_0673	542541	542936	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D gb|AAF74082.1| (AF212845) ORF129 [Lactococcus lactis bacteriophage ul36]	gene	gene543	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0673
SPy_0674	SPy0674		SPy_0674	542933	543154	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene544	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0674
SPy_0676	SPy0676		SPy_0676	543431	544066	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D gb|AAB18697.1| (U38906) ORF22 [Bacteriophage r1t]	gene	gene545	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0676
SPy_0677	SPy0677		SPy_0677	544339	544773	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D pir||T13313 hypothetical protein 24 - Streptococcus phage phi-O1205 >gi|2444104|gb|AAC79540.1| (U88974) ORF24 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene546	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0677
SPy_0679	SPy0679		SPy_0679	545083	546249	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D dbj|BAB07254.1| (AP001519) unknown [Bacillus halodurans]	gene	gene547	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0679
SPy_0680	SPy0680		SPy_0680	546592	547068	+	hypothetical protein	Best Blastp hit %3D gi|10879409 similar to smoothelin (H. sapiens) [Homo sapiens]	gene	gene548	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0680
SPy_0681	SPy0681		SPy_0681	547151	548362	+	hypothetical protein	Best Blastp hit %3D emb|CAB53788.1| (AJ242593) putative terminase large subunit [Bacteriophage A118]	gene	gene549	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0681
SPy_0682	SPy0682		SPy_0682	548376	549878	+	putative minor capsid protein%2C phage associated	Best Blastp hit %3D pir||T13205 minor capsid protein R508 - Lactobacillus phage phi-gle >gi|1926349|emb|CAA66734.1| (X98106) minor capsid protein [Bacteriophage phig1e]	gene	gene550	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0682
SPy_0683	SPy0683		SPy_0683	549883	551376	+	putative minor capsid protein%2C phage associated	Best Blastp hit %3D emb|CAB53790.1| (AJ242593) gp4 [Bacteriophage A118]	gene	gene551	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0683
SPy_0684	SPy0684		SPy_0684	551376	551603	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene552	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0684
SPy_0685	SPy0685		SPy_0685	551690	551956	+	hypothetical protein	Best Blastp hit %3D pir||T25808 hypothetical protein K08B12.5 - Caenorhabditis elegans >gi|1938422|gb|AAB52260.1| (U97001) Similar to serine/threonine-protein kinase%3B coded for by C. elegans cDNA CEESP52F%3B coded for by C. elegans cDNA yk134e9.5%3B coded for by C. elegans cDNA yk17b9.5%3B coded for by C. elegans cDNA CEESK86FB%3B coded for by C. elegans cDNA yk17b9.3%3B co>	gene	gene553	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0685
SPy_0686	SPy0686		SPy_0686	552082	552696	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene554	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0686
SPy_0688	SPy0688		SPy_0688	552700	553518	+	putative major head protein%2C phage associated	Best Blastp hit %3D emb|CAA59185.1| (X84706) major head protein [Bacteriophage B1]	gene	gene555	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0688
SPy_0689	SPy0689		SPy_0689	553572	553988	+	hypothetical protein	Best Blastp hit %3D sp|Q04774|YG34_BPMV4 HYPOTHETICAL 15.6 KD PROTEIN IN G34 3'REGION (ORF4) >gi|478257|pir||I45691 hypothetical protein 4 [imported] - Lactobacillus delbrueckii subsp. bulgaricus phage mv4 >gi|215250|gb|AAA56849.1| (L02497) ORF4%3B putative [Bacteriophage mv4]	gene	gene556	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0689
SPy_0690	SPy0690		SPy_0690	553978	554310	+	hypothetical protein	Best Blastp hit %3D pir||T13210 minor capsid protein R117a - Lactobacillus phage phi-gle >gi|1926354|emb|CAA66739.1| (X98106) minor capsid protein [Bacteriophage phig1e]	gene	gene557	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0690
SPy_0691	SPy0691		SPy_0691	554310	554666	+	hypothetical protein	Best Blastp hit %3D gb|AAC00538.1| (L02496) unknown protein [Bacteriophage LL-H]	gene	gene558	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0691
SPy_0693	SPy0693		SPy_0693	554663	555061	+	putative minor capsid protein%2C phage associated	Best Blastp hit %3D pir||T13212 minor capsid protein R135 - Lactobacillus phage phi-gle >gi|1926356|emb|CAA66741.1| (X98106) minor capsid protein [Bacteriophage phig1e]	gene	gene559	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0693
SPy_0694	SPy0694		SPy_0694	555061	555531	+	putative major tail shaft protein%2C phage associated	Best Blastp hit %3D emb|CAB53798.1| (AJ242593) major tail shaft protein [Bacteriophage A118]	gene	gene560	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0694
SPy_0695	SPy0695		SPy_0695	555584	556018	+	hypothetical protein	Best Blastp hit %3D emb|CAB72529.1| (AL139074) hypothetical protein Cj0036 [Campylobacter jejuni]	gene	gene561	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0695
SPy_0696	SPy0696		SPy_0696	556022	556603	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D emb|CAB53801.1| (AJ242593) gp15 [Bacteriophage A118]	gene	gene562	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0696
SPy_0697	SPy0697		SPy_0697	556593	559853	+	hypothetical protein	Best Blastp hit %3D pir||T13329 hypothetical protein 40 - Streptococcus phage phi-O1205 >gi|2444119|gb|AAC79555.1| (U88974) ORF40 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene563	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0697
SPy_0698	SPy0698		SPy_0698	559850	560566	+	hypothetical protein	Best Blastp hit %3D gb|AAG18639.1| (AY007505) unknown [Streptococcus mitis]	gene	gene564	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0698
SPy_0700	SPy0700		SPy_0700	560563	562707	+	hypothetical protein	Best Blastp hit %3D gi|9633054 hypothetical protein [Lactobacillus bacteriophage phi adh] >gi|5730311|emb|CAB52532.1| (AJ131519) hypothetical protein [Lactobacillus bacteriophage phi adh]	gene	gene565	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0700
SPy_0701	SPy0701	hylP1	hylP1	562704	563717	+	hyaluronidase%2C phage associated	Best Blastp hit %3D sp|Q54699|HYAL_BPH45 HYALURONOGLUCOSAMINIDASE (HYALURONIDASE) >gi|881507|gb|AAA86895.1| (U28144) hyaluronidase [Streptococcus pyogenes]	gene	gene566	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0701
SPy_0702	SPy0702		SPy_0702	563732	565618	+	hypothetical protein	Best Blastp hit %3D sp|P15317|YHYA_BPH44 HYPOTHETICAL 65 KD PROTEIN IN HYALURONIDASE REGION >gi|76370|pir||B30566 hypothetical protein - Streptococcus pyogenes phage H4489A >gi|215054|gb|AAA98102.1| (M19348) ORF [Streptococcus pyogenes phage H4489A]	gene	gene567	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0702
SPy_0703	SPy0703		SPy_0703	565630	566061	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene568	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0703
SPy_0705	SPy0705		SPy_0705	566064	566681	+	hypothetical protein	Best Blastp hit %3D pir||T13336 hypothetical protein 47 - Streptococcus phage phi-O1205 >gi|2444126|gb|AAC79562.1| (U88974) ORF47 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene569	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0705
SPy_0706	SPy0706		SPy_0706	566691	566966	+	hypothetical protein	Best Blastp hit %3D pir||T07111 MAR binding filament-like protein 1 - tomato >gi|1771158|emb|CAA69181.1| (Y07861) MFP1 protein [Lycopersicon esculentum]	gene	gene570	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0706
SPy_0707	SPy0707		SPy_0707	566963	567190	+	putative holin%2C phage associated	Best Blastp hit %3D gi|9635033 putative holin [Streptococcus thermophilus bacteriophage Sfi11] >gi|7521136|pir||T13643 probable holin - Streptococcus phage phi-Sfi11 >gi|3540293|gb|AAC34420.1| (AF158600) putative holin [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene571	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0707
SPy_0710	SPy0710		SPy_0710	567306	568508	+	conserved hypothetical protein%2C phage associated	Best Blastp hit %3D pir||T13528 hypothetical protein 39 - Bacillus phage phi-105 >gi|4126625|dbj|BAA36645.1| (AB016282) ORF39 [bacteriophage phi-105]	gene	gene572	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0710
SPy_0711	SPy0711	speC	speC	568576	569283	-	pyrogenic exotoxin C precursor%2C phage associated	Best Blastp hit %3D pir||A30509 exotoxin C precursor - Streptococcus pyogenes >gi|153821|gb|AAA27017.1| (M35514) streptococcal pyrogenic exotoxin type C (speC) precursor [Streptococcus pyogenes]	gene	gene573	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0711
SPy_0712	SPy0712	mf2	mf2	569394	570152	-	putative DNase	similar to mitogenic factor%3B phage associated%3B Best Blastp hit %3D sp|Q03158|NUCE_STRPN DNA-ENTRY NUCLEASE (COMPETENCE-SPECIFIC NUCLEASE) >gi|98025|pir||S10641 endA protein - Streptococcus pneumoniae >gi|47374|emb|CAA38134.1| (X54225) membrane nuclease [Streptococcus pneumoniae]	gene	gene574	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0712
SPy_0713	SPy0713	pepD	pepD	570464	571882	+	putative dipeptidase	Best Blastp hit %3D emb|CAA86210.1| (Z38063) dipeptidase [Lactobacillus helveticus]	gene	gene575	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0713
SPy_0714	SPy0714	adcA	adcA	572034	573581	+	putative adhesion protein	Best Blastp hit %3D emb|CAA96185.1| (Z71552) AdcA protein [Streptococcus pneumoniae]	gene	gene576	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0714
SPy_0715	SPy0715		SPy_0715	573729	574451	+	putative transcriptional regulator (GntR family)	Best Blastp hit %3D dbj|BAB04138.1| (AP001508) transcriptional regulator (GntR family) [Bacillus halodurans]	gene	gene577	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0715
SPy_0716	SPy0716	agaS	agaS	574470	575669	+	putative tagatose-6-phosphate aldose/ketose isomerase	Best Blastp hit %3D sp|P42907|AGAS_ECOLI PUTATIVE TAGATOSE-6-PHOSPHATE KETOSE/ALDOSE ISOMERASE >gi|7465773|pir||D65103 agaS protein - Escherichia coli (strain K-12) >gi|606076|gb|AAA57939.1| (U18997) ORF_o384 [Escherichia coli] >gi|1789525|gb|AAC76170.1| (AE000395) putative tagatose-6-phosphate aldose/ketose isomerase [Escherichia coli]	gene	gene578	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0716
SPy_0717	SPy0717	rpmE	rpmE	575766	576026	-	50S ribosomal protein L31	Best Blastp hit %3D sp|Q9ZH28|RL31_LISMO 50S RIBOSOMAL PROTEIN L31	gene	gene579	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0717
SPy_0720	SPy0720		SPy_0720	576141	577082	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06892.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene580	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0720
SPy_0721	SPy0721		SPy_0721	577476	577925	+	putative flavodoxin	Best Blastp hit %3D sp|O34737|FLAV_BACSU PROBABLE FLAVODOXIN 1 >gi|7430912|pir||C69866 flavodoxin homolog ykuN - Bacillus subtilis >gi|2632235|emb|CAA10877.1| (AJ222587) YkuN protein [Bacillus subtilis] >gi|2633786|emb|CAB13288.1| (Z99111) similar to flavodoxin [Bacillus subtilis]	gene	gene581	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0721
SPy_0722	SPy0722		SPy_0722	578101	578385	+	hypothetical protein	Best Blastp hit %3D pir||D69207 conserved hypothetical protein MTH804 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621894|gb|AAB85304.1| (AE000858) chorismate mutase%2C subunit A [Methanobacterium thermoautotrophicum]	gene	gene582	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0722
SPy_0723	SPy0723		SPy_0723	578378	579640	+	putative transposase	Best Blastp hit %3D dbj|BAA75315.1| (AB011836) similar to Bordetella paraperlussis transposase for insertion sequence element(27%25-identity) [Bacillus halodurans] >gi|10173277|dbj|BAB04382.1| (AP001509) unknown conserved protein in others [Bacillus halodurans]	gene	gene583	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0723
SPy_0724	SPy0724	rplS	rplS	579755	580102	+	50S ribosomal protein L19	Best Blastp hit %3D sp|O34031|RL19_STRTR 50S RIBOSOMAL PROTEIN L19 >gi|2444079|gb|AAC01534.1| (U88973) ribosomal protein L19 [Streptococcus thermophilus]	gene	gene584	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0724
SPy_0725	SPy0725		SPy_0725	580383	580745	-		This sequence contains the C-terminal portion of a putative integrase gene	gene	gene586	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0725
SPy_0726	SPy0726		SPy_0726	581114	581674	+	hypothetical protein	Best Blastp hit %3D pir||A57362 gyrb protein - Streptococcus pneumoniae (fragment) >gi|1052803|emb|CAA58770.1| (X83917) orflgyrb [Streptococcus pneumoniae] >gi|1490396|emb|CAA91552.1| (Z67740) unidentified [Streptococcus pneumoniae]	gene	gene587	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0726
SPy_0727	SPy0727	gyrB	gyrB	581675	583627	+	putative DNA gyrase%2C subunit B	Best Blastp hit %3D emb|CAA91553.1| (Z67740) DNA gyrase [Streptococcus pneumoniae]	gene	gene588	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0727
SPy_0728	SPy0728		SPy_0728	583995	585719	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06924.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene589	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0728
SPy_0729	SPy0729		SPy_0729	585851	586309	-	hypothetical protein	Best Blastp hit %3D pir||B70008 hypothetical protein yueI - Bacillus subtilis >gi|2635672|emb|CAB15165.1| (Z99120) yueI [Bacillus subtilis]	gene	gene590	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0729
SPy_0731	SPy0731	eno	eno	586536	587843	+	putative enolase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAA81815.1| (AB029313) enolase [Streptococcus intermedius]	gene	gene591	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0731
SPy_0732	SPy0732		SPy_0732	588369	588959	-	hypothetical protein	Best Blastp hit %3D gb|AAF61316.1| (U96166) unknown [Streptococcus cristatus]	gene	gene592	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0732
SPy_0733	SPy0733		SPy_0733	589008	589259	-	hypothetical protein	Best Blastp hit %3D sp|Q62925|M3K1_RAT MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 1 (MAPK/ERK KINASE KINASE 1) (MEK KINASE 1) (MEKK 1) >gi|7514007|pir||T10757 MAP kinase kinase (EC 2.7.1.-) 1 - rat >gi|1354137|gb|AAC52596.1| (U48596) MAP kinase kinase kinase 1 [Rattus norvegicus]	gene	gene593	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0733
SPy_0735	SPy0735		SPy_0735	589626	591161	-		This gene contains a sequence supported frame shift mutation	gene	gene594	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0735
SPy_0737	SPy0737	epf	epf	591675	597812	+	putative extracellular matrix binding protein	Best Blastp hit %3D pir||T31110 extracellular matrix binding protein - Abiotrophia defectiva (fragment) >gi|3249003|gb|AAD03320.1| (AF067776) extracellular matrix binding protein [Abiotrophia defectiva]	gene	gene595	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0737
SPy_0738	SPy0738	sagA	sagA	598677	598838	+	streptolysin S associated protein	Best Blastp hit %3D gb|AAC19115.1| (AF067723) streptolysin S associated protein SAGA [Streptococcus pyogenes] >gi|3283388|gb|AAC25177.1| (AF067649) SagA [Streptococcus pyogenes]	gene	gene596	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0738
SPy_0739	SPy0739	sagB	sagB	599060	600010	+	streptolysin S associated ORF	Best Blastp hit %3D gb|AAC25178.1| (AF067649) SagB [Streptococcus pyogenes]	gene	gene597	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0739
SPy_0740	SPy0740	sagC	sagC	600007	601065	+	streptolysin S associated ORF	Best Blastp hit %3D gb|AAC25179.2| (AF067649) SagC [Streptococcus pyogenes]	gene	gene598	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0740
SPy_0741	SPy0741		SPy_0741	601085	602443	+	hypothetical protein	Best Blastp hit %3D pir||E64436 conserved hypothetical protein MJ1094 - Methanococcus jannaschii >gi|1499943|gb|AAB99097.1| (U67552) conserved hypothetical protein [Methanococcus jannaschii]	gene	gene599	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0741
SPy_0742	SPy0742		SPy_0742	602418	603089	+	hypothetical protein	Best Blastp hit %3D dbj|BAB04194.1| (AP001508) unknown conserved protein [Bacillus halodurans]	gene	gene600	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0742
SPy_0743	SPy0743		SPy_0743	603086	603769	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene601	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0743
SPy_0744	SPy0744		SPy_0744	603792	604715	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||G69803 ABC transporter (ATP-binding protein) homolog yfiL - Bacillus subtilis >gi|1817536|dbj|BAA11402.1| (D78508) YfiL [Bacillus subtilis] >gi|2633155|emb|CAB12660.1| (Z99108) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene602	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0744
SPy_0745	SPy0745	sagH	sagH	604724	605851	+	ABC transporter (ATP-binding protein) - streptolysin S associated ORF	Best Blastp hit %3D gb|AAD49330.1|AF163682_1 (AF163682) SagH [Streptococcus pyogenes]	gene	gene603	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0745
SPy_0746	SPy0746		SPy_0746	605848	606966	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||A69804 ABC transporter (ATP-binding protein) homolog yfiN - Bacillus subtilis >gi|1817538|dbj|BAA11404.1| (D78508) YfiN [Bacillus subtilis] >gi|2633157|emb|CAB12662.1| (Z99108) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene604	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0746
SPy_0747	SPy0747		SPy_0747	607537	610269	+	hypothetical protein	Best Blastp hit %3D pir||T36922 probable large secreted protein - Streptomyces coelicolor >gi|5420017|emb|CAB46409.1| (AL096743) putative large secreted protein [Streptomyces coelicolor A3(2)]	gene	gene605	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0747
SPy_0749	SPy0749		SPy_0749	610547	611047	+	hypothetical protein	Best Blastp hit %3D emb|CAA68244.1| (X99978) citrulline cluster-linked gene [Lactobacillus plantarum]	gene	gene606	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0749
SPy_0751	SPy0751	lig	lig	611241	613199	+	putative DNA ligase	Best Blastp hit %3D sp|O87703|DNLJ_BACST DNA LIGASE (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) >gi|3688229|emb|CAA09732.1| (AJ011676) DNA ligase [Bacillus stearothermophilus]	gene	gene607	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0751
SPy_0752	SPy0752		SPy_0752	613213	614235	+	hypothetical protein	Best Blastp hit %3D pir||F69795 conserved hypothetical protein yerQ - Bacillus subtilis >gi|2632986|emb|CAB12492.1| (Z99107) similar to hypothetical proteins [Bacillus subtilis]	gene	gene608	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0752
SPy_0754	SPy0754	atpE	atpE	614628	614825	+	H+-transporting ATP synthase chain C	Best Blastp hit %3D gb|AAD00920.1| (AF001955) UncE [Streptococcus sanguinis]	gene	gene609	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0754
SPy_0755	SPy0755	atpB	atpB	614860	615576	+	putative proton-translocating ATPase a subunit	Best Blastp hit %3D gb|AAD00913.1| (AF001955) proton-translocating ATPase a subunit [Streptococcus sanguinis]	gene	gene610	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0755
SPy_0756	SPy0756	atpF	atpF	615594	616088	+	putative proton-translocating ATPase%2C subunit b	Best Blastp hit %3D sp|P95785|ATPF_STRMU ATP SYNTHASE B CHAIN >gi|7436260|pir||JC5737 membrane-bound proton-translocating ATPase (EC 3.6.1.-) b chain - Streptococcus mutans >gi|1773262|gb|AAD13379.1| (U31170) ATPase%2C b subunit [Streptococcus mutans]	gene	gene611	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0756
SPy_0757	SPy0757	atpH	atpH	616088	616624	+	putative proton-translocating ATPase%2C delta subunit	Best Blastp hit %3D sp|O50156|ATPD_STRBO ATP SYNTHASE DELTA CHAIN >gi|2662323|dbj|BAA23752.1| (AB009314) proton-translocating ATPase%2C delta subunit [Streptococcus bovis]	gene	gene612	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0757
SPy_0758	SPy0758	atpA	atpA	616640	618148	+	putative proton-translocating ATPase%2C alpha subunit	Best Blastp hit %3D dbj|BAA23753.1| (AB009314) proton-translocating ATPase%2C alpha subunit [Streptococcus bovis]	gene	gene613	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0758
SPy_0759	SPy0759	atpG	atpG	618164	619039	+	putative proton-translocating ATPase%2C gamma subunit	Best Blastp hit %3D dbj|BAA23754.1| (AB009314) proton-translocating ATPase%2C gamma subunit [Streptococcus bovis]	gene	gene614	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0759
SPy_0760	SPy0760	atpD	atpD	619201	620607	+	putative proton-translocating ATPase%2C beta subunit	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P95789|ATPB_STRMU ATP SYNTHASE BETA CHAIN >gi|4239652|gb|AAD13383.1| (U31170) ATPase%2C beta subunit [Streptococcus mutans]	gene	gene615	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0760
SPy_0761	SPy0761	atpC	atpC	620620	621036	+	putative proton-translocating ATPase%2C epsiron subunit	Best Blastp hit %3D dbj|BAA23756.1| (AB009314) proton-translocating ATPase%2C epsiron subunit [Streptococcus bovis]	gene	gene616	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0761
SPy_0762	SPy0762		SPy_0762	621302	621559	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene617	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0762
SPy_0763	SPy0763		SPy_0763	621624	622895	+	putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Best Blastp hit %3D sp|P70965|MUA1_BACSU UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE 1 (ENOYLPYRUVATE TRANSFERASE) (UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE) (EPT) >gi|7448125|pir||A69662 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA - Bacillus subtilis >gi|1648861|emb|CAB03688.1| (Z81356) UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Bacillus subtilis] >gi|2636201|emb|CAB15693.1| (Z99122) UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Bacillus subtilis]	gene	gene618	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0763
SPy_0764	SPy0764	epuA	epuA	622899	623087	+	conserved competence associated hypothetical protein	Best Blastp hit %3D sp|Q03159|EPUA_STRPN EPUA PROTEIN >gi|98026|pir||S10640 epuA protein - Streptococcus pneumoniae >gi|47373|emb|CAA38133.1| (X54225) 7 kDa protein [Streptococcus pneumoniae]	gene	gene619	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0764
SPy_0766	SPy0766	endA	endA	623123	623662	+	putative competence associated membrane nuclease	Best Blastp hit %3D sp|Q03158|NUCE_STRPN DNA-ENTRY NUCLEASE (COMPETENCE-SPECIFIC NUCLEASE) >gi|98025|pir||S10641 endA protein - Streptococcus pneumoniae >gi|47374|emb|CAA38134.1| (X54225) membrane nuclease [Streptococcus pneumoniae]	gene	gene620	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0766
SPy_0768	SPy0768	pheS	pheS	623867	624988	+	putative phenylalanyl-tRNA synthetase (alpha subunit)	Best Blastp hit %3D sp|P17921|SYFA_BACSU PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (PHENYLALANINE-TRNA LIGASE ALPHA CHAIN) (PHERS) >gi|7428485|pir||YFBSA phenylalanine-tRNA ligase (EC 6.1.1.20) alpha chain - Bacillus subtilis >gi|1770030|emb|CAA99603.1| (Z75208) phenylalany-tRNA synthetase beta subunit [Bacillus subtilis] >gi|2635329|emb|CAB14824.1| (Z99118) phenylalanyl-tRNA synthetase (alpha subunit) [Bacillus subtilis]	gene	gene621	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0768
SPy_0769	SPy0769	pheT	pheT	625198	627603	+	phenylalanyl-tRNA synthetase (beta subunit)	Best Blastp hit %3D sp|P17922|SYFB_BACSU PHENYLALANYL-TRNA SYNTHETASE BETA CHAIN (PHENYLALANINE-TRNA LIGASE BETA CHAIN) (PHERS) >gi|7428487|pir||YFBSB phenylalanine-tRNA ligase (EC 6.1.1.20) beta chain - Bacillus subtilis >gi|1770031|emb|CAA99564.1| (Z75208) phenylalanyl-tRNA synthetase beta subunit [Bacillus subtilis] >gi|2635328|emb|CAB14823.1| (Z99118) phenylalanyl-tRNA synthetase (beta subunit) [Bacillus subtilis]	gene	gene622	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0769
SPy_0770	SPy0770		SPy_0770	627713	628090	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene623	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0770
SPy_0771	SPy0771		SPy_0771	628083	628469	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene624	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0771
SPy_0772	SPy0772		SPy_0772	628542	629618	+	hypothetical protein	Best Blastp hit %3D pir||F75581 hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6460820|gb|AAF12525.1|AE001863_150 (AE001863) hypothetical protein [Deinococcus radiodurans]	gene	gene625	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0772
SPy_0773	SPy0773		SPy_0773	629628	630296	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||D69433 ABC transporter%2C ATP-binding protein homolog - Archaeoglobus fulgidus >gi|2649101|gb|AAB89781.1| (AE001001) ABC transporter%2C ATP-binding protein [Archaeoglobus fulgidus]	gene	gene626	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0773
SPy_0775	SPy0775		SPy_0775	630398	631315	-	hypothetical protein	Best Blastp hit %3D pir||A75256 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6460420|gb|AAF12131.1|AE002088_8 (AE002088) conserved hypothetical protein [Deinococcus radiodurans]	gene	gene627	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0775
SPy_0776	SPy0776	rexB	rexB	631466	634681	+	putative ATP-dependent exonuclease%2C subunit B	Best Blastp hit %3D pir||T30307 rexB protein - Lactococcus lactis >gi|2909715|gb|AAC12965.1| (U76424) exonuclease RexB [Lactococcus lactis]	gene	gene628	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0776
SPy_0777	SPy0777	rexA	rexA	634678	638310	+	putative ATP-dependent exonuclease%2C subunit A	Best Blastp hit %3D pir||T30308 rexA protein - Lactococcus lactis >gi|2909716|gb|AAC12966.1| (U76424) exonuclease RexA [Lactococcus lactis]	gene	gene629	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0777
SPy_0778	SPy0778		SPy_0778	638450	639262	+	putative ABC transporter (substrate-binding protein)	Best Blastp hit %3D dbj|BAB05180.1| (AP001512) ABC transporter (substrate-binding protein) [Bacillus halodurans]	gene	gene630	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0778
SPy_0779	SPy0779	rpsU	rpsU	639403	639579	+	30S ribosomal protein S21	Best Blastp hit %3D pir||T43742 ribosomal protein S21 [imported] - Listeria monocytogenes >gi|5689043|dbj|BAA82793.1| (AB023064) 30S ribosomal protein S21 [Listeria monocytogenes]	gene	gene631	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0779
SPy_0780	SPy0780	mscL	mscL	639707	640069	-	putative large conductance mechanosensitive channel	Best Blastp hit %3D sp|O68285|MSCL_STAAU LARGE-CONDUCTANCE MECHANOSENSITIVE CHANNEL >gi|3135292|gb|AAC38560.1| (AF029731) large conductance mechanosensitive channel [Staphylococcus aureus]	gene	gene632	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0780
SPy_0781	SPy0781	dnaG	dnaG	640200	642014	+	putative DNA primase	Best Blastp hit %3D sp|Q04505|PRIM_LACLA DNA PRIMASE >gi|1075726|pir||JC2485 DNA primase (EC 2.7.7.-) dnaG - Lactococcus lactis >gi|1094407|prf||2106154A DNA primase [Lactococcus lactis]	gene	gene633	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0781
SPy_0782	SPy0782	rpoD	rpoD	642023	643132	+	putative RNA polymerase sigma 42 protein	Best Blastp hit %3D dbj|BAA21507.1| (AB000631) sigma 42 protein [Streptococcus mutans]	gene	gene634	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0782
SPy_0783	SPy0783		SPy_0783	643368	643706	+	hypothetical protein	Best Blastp hit %3D dbj|BAA21508.1| (AB000631) unnamed protein product [Streptococcus mutans]	gene	gene635	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0783
SPy_0784	SPy0784	rmlD	rmlD	643844	644698	+	putative dTDP-4-keto-L-rhamnose reductase	Best Blastp hit %3D dbj|BAA21509.1| (AB000631) dTDP-4-keto-L-rhamnose reductase [Streptococcus mutans]	gene	gene636	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0784
SPy_0786	SPy0786	rgpAc	rgpAc	644817	645971	+	conserved hypothetical protein - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00086 rgpAc protein - Streptococcus mutans >gi|3399704|dbj|BAA32089.1| (AB010970) rgpAc [Streptococcus mutans]	gene	gene637	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0786
SPy_0787	SPy0787	rgpBc	rgpBc	645961	646893	+	putative rhamnosyltransferase - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00087 rhamnosyltransferase - Streptococcus mutans >gi|3399705|dbj|BAA32090.1| (AB010970) rhamnosyltransferase [Streptococcus mutans]	gene	gene638	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0787
SPy_0789	SPy0789	rgpCc	rgpCc	646938	647699	+	putative ABC-transporter (permease protein) - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00088 ABC-type transport protein rgpCc - Streptococcus mutans >gi|3399706|dbj|BAA32091.1| (AB010970) ABC-transporter [Streptococcus mutans]	gene	gene639	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0789
SPy_0790	SPy0790	rgpDc	rgpDc	647699	648904	+	ABC-transporter (ATP-binding protein) - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00089 ABC transporter rgpDc - Streptococcus mutans >gi|3399707|dbj|BAA32092.1| (AB010970) ABC-transporter [Streptococcus mutans]	gene	gene640	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0790
SPy_0791	SPy0791	rgpEc	rgpEc	648929	649936	+	putative glycosyltransferase - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00090 glycosyltransferase rgpEc - Streptococcus mutans >gi|3399708|dbj|BAA32093.1| (AB010970) glycosyltransferase [Streptococcus mutans]	gene	gene641	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0791
SPy_0792	SPy0792	rgpFc	rgpFc	649933	651678	+	conserved hypothetical protein - possibly involved in cell wall localization and side chain formation of rhamnose-glucose polysaccharide	Best Blastp hit %3D pir||T00091 rgpFc protein - Streptococcus mutans >gi|3399709|dbj|BAA32094.1| (AB010970) rgpFc [Streptococcus mutans]	gene	gene642	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0792
SPy_0793	SPy0793		SPy_0793	651675	654149	+	hypothetical protein	Best Blastp hit %3D pir||T00092 hypothetical protein 7 - Streptococcus mutans >gi|3399710|dbj|BAA32095.1| (AB010970) ORF7 [Streptococcus mutans]	gene	gene643	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0793
SPy_0794	SPy0794		SPy_0794	654328	655023	+	putative glycosyl transferase	Best Blastp hit %3D dbj|BAA19644.1| (AB002668) unnamed protein product [Actinobacillus actinomycetemcomitans]	gene	gene644	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0794
SPy_0796	SPy0796		SPy_0796	655025	655366	+	hypothetical protein	Best Blastp hit %3D dbj|BAA19645.1| (AB002668) unnamed protein product [Actinobacillus actinomycetemcomitans]	gene	gene645	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0796
SPy_0797	SPy0797		SPy_0797	655359	656645	+	hypothetical protein	Best Blastp hit %3D sp|P39855|CAPF_STAAU CAPF PROTEIN >gi|506702|gb|AAA64645.1| (U10927) CapF [Staphylococcus aureus]	gene	gene646	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0797
SPy_0798	SPy0798		SPy_0798	656626	658122	+	hypothetical protein	Best Blastp hit %3D dbj|BAA19642.1| (AB002668) unnamed protein product [Actinobacillus actinomycetemcomitans]	gene	gene647	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0798
SPy_0799	SPy0799	pepT	pepT	658216	659439	+	putative tripeptidase	Best Blastp hit %3D sp|P42020|PEPT_LACLC PEPTIDASE T (AMINOTRIPEPTIDASE) (TRIPEPTIDASE) >gi|495046|gb|AAA20627.1| (L27596) tripeptidase [Lactococcus lactis]	gene	gene648	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0799
SPy_0800	SPy0800		SPy_0800	659480	659968	+	putative pore-forming peptide	Best Blastp hit %3D sp|P36920|EBSA_ENTFA PORE FORMING PROTEIN EBSA >gi|1075690|pir||A49939 ebsA protein - Enterococcus faecalis >gi|388107|gb|AAC36851.1| (L23802) pore-forming peptide [Enterococcus faecalis]	gene	gene649	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0800
SPy_0801	SPy0801		SPy_0801	659955	660152	-	ferredoxin	Best Blastp hit %3D sp|P50727|FER_BACSU FERREDOXIN >gi|7430771|pir||D69621 ferredoxin fer - Bacillus subtilis >gi|1146198|gb|AAC83945.1| (L47648) ferredoxin [Bacillus subtilis] >gi|2634722|emb|CAB14220.1| (Z99115) ferredoxin [Bacillus subtilis] >gi|2634739|emb|CAB14236.1| (Z99116) ferredoxin [Bacillus subtilis]	gene	gene650	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0801
SPy_0802	SPy0802		SPy_0802	660201	660677	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene651	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0802
SPy_0803	SPy0803	cmk	cmk	660692	661372	+	putative cytidylate kinase	Best Blastp hit %3D sp|P38493|KCY_BACSU CYTIDYLATE KINASE (CK) (CYTIDINE MONOPHOSPHATE KINASE) (CMP KINASE) >gi|7448348|pir||F69601 cytidylate kinase cmk - Bacillus subtilis >gi|533105|gb|AAA85149.1| (U11687) unknown [Bacillus subtilis] >gi|1146214|gb|AAC83961.1| (L47648) cytidine monophosphate kinase [Bacillus subtilis] >gi|2634707|emb|CAB14205.1| (Z99115) cytidylate kinase [Bacillus subtilis] >gi|2634724|emb|CAB14221.1| (Z99116) cytidylate kinase [Bacillus subtilis]	gene	gene652	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0803
SPy_0804	SPy0804	infC	infC	661534	662064	+	putative translation initiation factor 3 (IF3)	Best Blastp hit %3D sp|O53084|IF3_LISMO TRANSLATION INITIATION FACTOR IF-3 >gi|2879775|emb|CAA68920.1| (Y07640) translation initiation factor%2C IF3 [Listeria monocytogenes]	gene	gene653	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0804
SPy_0805	SPy0805	rpmI	rpmI	662106	662303	+	50S ribosomal protein L35	Best Blastp hit %3D sp|P13069|RL35_BACST 50S RIBOSOMAL PROTEIN L35 >gi|71371|pir||R5BS35 ribosomal protein L35 - Bacillus stearothermophilus >gi|39962|emb|CAA34313.1| (X16188) ribosomal protein L35 (AA 1-66) [Bacillus stearothermophilus]	gene	gene654	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0805
SPy_0806	SPy0806	rplT	rplT	662362	662721	+	50S ribosomal protein L20	Best Blastp hit %3D dbj|BAB06857.1| (AP001517) ribosomal protein L20 [Bacillus halodurans]	gene	gene655	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0806
SPy_0807	SPy0807		SPy_0807	663012	665222	-	hypothetical protein	Best Blastp hit %3D pir||C69810 anion-binding protein homolog yflE - Bacillus subtilis >gi|2443227|dbj|BAA22298.1| (D86417) YflE [Bacillus subtilis] >gi|2633095|emb|CAB12600.1| (Z99108) similar to anion-binding protein [Bacillus subtilis]	gene	gene656	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0807
SPy_0808	SPy0808		SPy_0808	665330	666493	+	hypothetical protein	Best Blastp hit %3D sp|P39587|YWBD_BACSU HYPOTHETICAL 44.4 KD PROTEIN IN EPR-GALK INTERGENIC REGION >gi|629026|pir||S39674 ywbD protein - Bacillus subtilis >gi|413943|emb|CAA51575.1| (X73124) ipa-19d [Bacillus subtilis] >gi|2636371|emb|CAB15862.1| (Z99123) alternate gene name: ipa-19d~similar to hypothetical proteins [Bacillus subtilis]	gene	gene657	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0808
SPy_0809	SPy0809	aroD	aroD	666490	667176	+	putative 3-dehydroquinate dehydratase	Best Blastp hit %3D sp|P24670|AROD_SALTI 3-DEHYDROQUINATE DEHYDRATASE (3-DEHYDROQUINASE) (TYPE I DHQASE) >gi|96689|pir||S15652 3-dehydroquinate dehydratase (EC 4.2.1.10) aroD - Salmonella typhi >gi|7546223|pdb|1QFE|A Chain A%2C The Structure Of Type I 3-Dehydroquinate Dehydratase From Salmonella Typhi >gi|7546224|pdb|1QFE|B Chain B%2C The Structure Of Type I 3-Dehydroquinate Dehydratase From Salmonella Typhi >gi|47642|emb|CAA38418.1| (X54546) 5-dehydroquinate hydrolyase (3-dehydroquinase) [Salmonella typhi]	gene	gene658	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0809
SPy_0810	SPy0810	aroF	aroF	667270	668436	+	putative chorismate synthase	Best Blastp hit %3D dbj|BAB05375.1| (AP001512) chorismate synthase [Bacillus halodurans]	gene	gene659	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0810
SPy_0811	SPy0811		SPy_0811	668497	668838	+	hypothetical protein	Best Blastp hit %3D pir||A69828 hypothetical protein yheA - Bacillus subtilis >gi|2226157|emb|CAA74444.1| (Y14080) hypothetical protein [Bacillus subtilis] >gi|2633315|emb|CAB12819.1| (Z99109) yheA [Bacillus subtilis]	gene	gene660	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0811
SPy_0813	SPy0813	gor	gor	669059	670411	+	putative glutathione reductase (GR)	Best Blastp hit %3D dbj|BAA76640.1| (AB019579) glutathione reductase (GR) [Streptococcus mutans]	gene	gene661	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0813
SPy_0814	SPy0814	folC.2	folC.2	670499	671767	-	putative folyl-polyglutamate synthetase	Best Blastp hit %3D dbj|BAB06756.1| (AP001517) folyl-polyglutamate synthetase [Bacillus halodurans]	gene	gene662	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0814
SPy_0815	SPy0815		SPy_0815	671797	672237	-	hypothetical protein	Best Blastp hit %3D gi|6323990 Yrf1-6p [Saccharomyces cerevisiae] >gi|1730660|sp|P53819|YN79_YEAST HYPOTHETICAL 211.1 KDA PROTEIN IN COS1 5'REGION >gi|2132793|pir||S63325 probable membrane protein YNL339c - yeast (Saccharomyces cerevisiae) >gi|2258153|emb|CAA96276.1| (Z71615) there is a second Y' element in the left%3B subtelomeric region of chromosome XIV%3B ORF YNL339c [Saccharomyces cerevisiae]	gene	gene663	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0815
SPy_0816	SPy0816		SPy_0816	672472	673614	+	putative iron-sulfur cofactor synthesis protein	Best Blastp hit %3D sp|P31672|NIFS_LACDE NIFS PROTEIN HOMOLOG >gi|98662|pir||S16047 nitrogenase cofactor synthesis protein nifS - Lactobacillus delbrueckii >gi|43985|emb|CAA43493.1| (X61190) nifS-like gene [Lactobacillus delbrueckii]	gene	gene664	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0816
SPy_0817	SPy0817	thiI	thiI	673626	674840	+	putative thiamine biosynthesis protein	Best Blastp hit %3D sp|O34595|THII_BACSU PROBABLE THIAMINE BIOSYNTHESIS PROTEIN THII >gi|7429879|pir||E69988 conserved hypothetical protein ytbJ - Bacillus subtilis >gi|2293230|gb|AAC00308.1| (AF008220) YtbJ [Bacillus subtilis] >gi|2635442|emb|CAB14936.1| (Z99119) similar to hypothetical proteins [Bacillus subtilis]	gene	gene665	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0817
SPy_0818	SPy0818		SPy_0818	674878	676170	+	hypothetical protein	Best Blastp hit %3D gi|10956446 pXO2-56 [Bacillus anthracis] >gi|6470207|gb|AAF13661.1|AF188935_59 (AF188935) pXO2-56 [Bacillus anthracis]	gene	gene666	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0818
SPy_0819	SPy0819	rplU	rplU	676384	676698	+	50S ribosomal protein L21	Best Blastp hit %3D dbj|BAB06730.1| (AP001517) ribosomal protein L21 (BL20) [Bacillus halodurans]	gene	gene667	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0819
SPy_0821	SPy0821		SPy_0821	676710	677036	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06729.1| (AP001517) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene668	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0821
SPy_0822	SPy0822	rpmA	rpmA	677064	677357	+	50S ribosomal protein L27	Best Blastp hit %3D sp|P05657|RL27_BACSU 50S RIBOSOMAL PROTEIN L27 (BL30) (BL24) >gi|80371|pir||C21895 ribosomal protein L27 - Bacillus subtilis >gi|40186|emb|CAA26492.1| (X02656) homologous to E.coli ribosomal protein L27 [Bacillus subtilis] >gi|2635259|emb|CAB14754.1| (Z99118) ribosomal protein L27 (BL24) [Bacillus subtilis]	gene	gene669	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0822
SPy_0824	SPy0824		SPy_0824	677705	678619	+	putative capsular polysaccharide biosynthesis protein	Best Blastp hit %3D pir||T44638 capsular polysaccharide biosynthesis protein cpsY [imported] - Streptococcus agalactiae >gi|4456788|emb|CAB36980.1| (Y17218) CpsY protein [Streptococcus agalactiae] >gi|4467988|emb|CAB36982.2| (Y17241) CpsY protein [Streptococcus agalactiae] >gi|5823210|gb|AAD53064.1|AF163833_1 (AF163833) CpsY [Streptococcus agalactiae]	gene	gene670	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0824
SPy_0826	SPy0826	lsp	lsp	678616	679074	+	putative prolipoprotein signal peptidase	Best Blastp hit %3D sp|Q48729|LSPA_LACLC LIPOPROTEIN SIGNAL PEPTIDASE (PROLIPOPROTEIN SIGNAL PEPTIDASE) (SIGNAL PEPTIDASE II) (SPASE II)	gene	gene671	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0826
SPy_0827	SPy0827		SPy_0827	679064	679954	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06261.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene672	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0827
SPy_0830	SPy0830	pyrR	pyrR	680350	680871	+	putative pyrimidine regulatory protein	Best Blastp hit %3D emb|CAB89869.1| (AJ132624) pyrimidine regulatory protein [Lactococcus lactis]	gene	gene673	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0830
SPy_0831	SPy0831	pyrP	pyrP	680887	682146	+	putative uracil permease	Best Blastp hit %3D emb|CAB89870.1| (AJ132624) uracil transporter [Lactococcus lactis]	gene	gene674	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0831
SPy_0832	SPy0832	pyrB	pyrB	682207	683142	+	putative aspartate transcarbamoylase	Best Blastp hit %3D gb|AAF72727.1| (AF264709) aspartate transcarbamoylase [Enterococcus faecalis]	gene	gene675	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0832
SPy_0833	SPy0833	carA	carA	683186	684268	+	putative carbamoyl phosphate synthetase small subunit	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAB89872.1| (AJ132624) carbamoyl phosphate synthetase small subunit [Lactococcus lactis]	gene	gene676	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0833
SPy_0835	SPy0835	carB	carB	684494	687670	+	putative carbamoylphosphate synthetase	Best Blastp hit %3D emb|CAA03928.1| (AJ000109) carbamoylphosphate synthetase [Lactococcus lactis]	gene	gene677	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0835
SPy_0836	SPy0836		SPy_0836	687877	689148	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06842.1| (AP001517) unknown conserved protein [Bacillus halodurans]	gene	gene678	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0836
SPy_0837	SPy0837		SPy_0837	689172	689858	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||D69858 ABC transporter (ATP-binding protein) homolog yknY - Bacillus subtilis >gi|2633807|emb|CAB13309.1| (Z99111) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis] >gi|3282120|gb|AAC24910.1| (AF012285) YknY [Bacillus subtilis]	gene	gene679	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0837
SPy_0838	SPy0838		SPy_0838	689870	691090	+	hypothetical protein	Best Blastp hit %3D sp|O31712|YKNZ_BACSU HYPOTHETICAL 42.1 KDA PROTEIN IN MOAD-FRUR INTERGENIC REGION >gi|7474621|pir||E69858 conserved hypothetical protein yknZ - Bacillus subtilis >gi|2633808|emb|CAB13310.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis] >gi|3282122|gb|AAC24912.1| (AF012285) YknZ [Bacillus subtilis]	gene	gene680	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0838
SPy_0839	SPy0839		SPy_0839	691344	693077	+	putative glycerophosphodiester phosphodiesterase	Best Blastp hit %3D pir||E69827 glycerophosphodiester phosphodiesterase homolog yhdW - Bacillus subtilis >gi|2226218|emb|CAA74507.1| (Y14082) hypothetical protein [Bacillus subtilis] >gi|2633297|emb|CAB12801.1| (Z99109) similar to glycerophosphodiester phosphodiesterase [Bacillus subtilis]	gene	gene681	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0839
SPy_0840	SPy0840	rpsP	rpsP	693204	693476	+	30S ribosomal protein S16	Best Blastp hit %3D dbj|BAB06202.1| (AP001515) ribosomal protein S16 (BS17) [Bacillus halodurans]	gene	gene682	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0840
SPy_0841	SPy0841		SPy_0841	693486	693725	+	hypothetical protein	Best Blastp hit %3D sp|O31738|YLQC_BACSU HYPOTHETICAL 9.1 KDA PROTEIN IN RPSP-TRMD INTERGENIC REGION >gi|7430170|pir||C69880 conserved hypothetical protein ylqC - Bacillus subtilis >gi|2633972|emb|CAB13473.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene683	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0841
SPy_0843	SPy0843		SPy_0843	694636	697662	+	hypothetical protein	Best Blastp hit %3D pir||T31094 surface antigen BspA - Bacteroides forsythus >gi|3005673|gb|AAC82625.1| (AF054892) surface antigen BspA [Bacteroides forsythus]	gene	gene684	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0843
SPy_0844	SPy0844		SPy_0844	697682	698083	+	hypothetical protein	Best Blastp hit %3D pir||G69153 conserved hypothetical protein MTH413 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621476|gb|AAB84919.1| (AE000825) conserved protein [Methanobacterium thermoautotrophicum]	gene	gene685	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0844
SPy_0845	SPy0845	czcD	czcD	698263	699138	-	putative cation-efflux system membrane protein	Best Blastp hit %3D pir||T44365 cation-efflux system membrane protein homolog [imported] - Staphylococcus aureus >gi|4126672|dbj|BAA36686.1| (AB016431) czcD [Staphylococcus aureus]	gene	gene686	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0845
SPy_0846	SPy0846		SPy_0846	699274	699795	+	hypothetical protein	Best Blastp hit %3D gb|AAG09969.1|AF248037_4 (AF248037) unknown [Streptococcus agalactiae]	gene	gene687	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0846
SPy_0847	SPy0847		SPy_0847	700010	700528	+	putative 16S rRNA processing protein	Best Blastp hit %3D sp|O31740|RIMM_BACSU PROBABLE 16S RRNA PROCESSING PROTEIN RIMM >gi|7474649|pir||E69880 conserved hypothetical protein ylqE - Bacillus subtilis >gi|2633974|emb|CAB13475.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene688	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0847
SPy_0849	SPy0849	trmD	trmD	700518	701249	+	putative tRNA (guanine-N1)-methyltransferase	Best Blastp hit %3D dbj|BAB06198.1| (AP001515) tRNA methyltransferase [Bacillus halodurans]	gene	gene689	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0849
SPy_0850	SPy0850		SPy_0850	701249	702241	+	putative thioredoxin reductase	Best Blastp hit %3D pir||B70015 thioredoxin reductase homolog yumC - Bacillus subtilis >gi|1934830|emb|CAB07954.1| (Z93939) thioredoxine reductase [Bacillus subtilis] >gi|2635708|emb|CAB15201.1| (Z99120) similar to thioredoxin reductase [Bacillus subtilis]	gene	gene690	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0850
SPy_0851	SPy0851		SPy_0851	702419	703477	+	probable regulatory protein	Best Blastp hit %3D pir||E71373 probable regulatory protein (pfoS/R) - syphilis spirochete >gi|3322295|gb|AAC65034.1| (AE001189) regulatory protein (pfoS/R) [Treponema pallidum]	gene	gene691	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0851
SPy_0852	SPy0852	apbA	apbA	703490	704413	+	putative 2-dehydropantoate 2-reductase	Best Blastp hit %3D pir||H75119 probable 2-dehydropantoate 2-reductase (EC 1.1.1.169) PAB0512 - Pyrococcus abyssi (strain Orsay) >gi|5458184|emb|CAB49673.1| (AJ248285) PROBABLE 2-DEHYDROPANTOATE 2-REDUCTASE (EC 1.1.1.169) [Pyrococcus abyssi]	gene	gene692	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0852
SPy_0853	SPy0853		SPy_0853	704669	705382	+	putative transcriptional repressor	Best Blastp hit %3D dbj|BAB04545.1| (AP001510) transcriptional repressor [Bacillus halodurans]	gene	gene693	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0853
SPy_0854	SPy0854	fruB	fruB	705379	706290	+	putative fructose-1-phosphate kinase	Best Blastp hit %3D sp|O31714|K1PF_BACSU 1-PHOSPHOFRUCTOKINASE (FRUCTOSE 1-PHOSPHATE KINASE) >gi|7434216|pir||A69627 fructose 1-phosphate kinase fruB - Bacillus subtilis >gi|2633810|emb|CAB13312.1| (Z99111) fructose-1-phosphate kinase [Bacillus subtilis] >gi|3282124|gb|AAC24914.1| (AF012285) fructose-1-phosphate kinase [Bacillus subtilis]	gene	gene694	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0854
SPy_0855	SPy0855		SPy_0855	706287	708233	+	putative fructose-specific enzyme II%2C PTS system BC component	Best Blastp hit %3D dbj|BAB04547.1| (AP001510) PTS system%2C fructose-specific enzyme II%2C BC component [Bacillus halodurans]	gene	gene695	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0855
SPy_0856	SPy0856	mur1.1	mur1.1	708326	708925	+	putative peptidoglycan hydrolase	Best Blastp hit %3D emb|CAB94815.1| (AJ245582) peptidoglycan hydrolase [Streptococcus thermophilus]	gene	gene696	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0856
SPy_0857	SPy0857	mur1.2	mur1.2	709077	709784	+	putative peptidoglycan hydrolase	Best Blastp hit %3D emb|CAB94815.1| (AJ245582) peptidoglycan hydrolase [Streptococcus thermophilus]	gene	gene697	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0857
SPy_0858	SPy0858		SPy_0858	709841	710176	-			gene	gene698	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0858
SPy_0861	SPy0861		SPy_0861	710740	711759	-	hypothetical protein	Best Blastp hit %3D sp|P11215|ITAM_HUMAN CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA SUBUNIT PRECURSOR (CR-3 ALPHA CHAIN) (CD11B) (LEUKOCYTE ADHESION RECEPTOR MO1) (INTEGRIN ALPHA-M) (NEUTROPHIL ADHERENCE RECEPTOR) >gi|263049|gb|AAB24821.1| (S52228) leukocyte integrin alpha chain [human%2C Peptide%2C 1152 aa] [Homo sapiens]	gene	gene699	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0861
SPy_0863	SPy0863		SPy_0863	712240	712469	+			gene	gene700	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0863
SPy_0864	SPy0864		SPy_0864	712662	713042	+	hypothetical protein	Best Blastp hit %3D sp|O67825|IF2_AQUAE TRANSLATION INITIATION FACTOR IF-2 >gi|7443418|pir||E70474 translation initiation factor IF-2 - Aquifex aeolicus >gi|2984268|gb|AAC07794.1| (AE000769) initiation factor IF-2 [Aquifex aeolicus]	gene	gene701	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0864
SPy_0865	SPy0865		SPy_0865	713042	713890	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07346.1| (AP001519) unknown conserved protein [Bacillus halodurans]	gene	gene702	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0865
SPy_0866	SPy0866	papS	papS	714030	715223	+	putative poly(A) polymerase	Best Blastp hit %3D sp|P42977|PAPS_BACSU POLY(A) POLYMERASE (PAP) >gi|7475758|pir||B69672 poly(A) polymerase papS - Bacillus subtilis >gi|1146238|gb|AAB38446.1| (L47709) poly(A) polymerase [Bacillus subtilis] >gi|2634663|emb|CAB14161.1| (Z99115) poly(A) polymerase [Bacillus subtilis]	gene	gene703	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0866
SPy_0867	SPy0867		SPy_0867	715220	717097	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||A69814 ABC transporter (ATP-binding protein) homolog yfmR - Bacillus subtilis >gi|2116756|dbj|BAA20107.1| (D86418) YfmR [Bacillus subtilis] >gi|2633050|emb|CAB12556.1| (Z99107) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis] >gi|2633061|emb|CAB12566.1| (Z99108) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene704	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0867
SPy_0870	SPy0870	fms	fms	717990	718400	+	putative polypeptide deformylase	Best Blastp hit %3D sp|O08450|DEF_CLOBE POLYPEPTIDE DEFORMYLASE (PDF) (FORMYLMETHIONINE DEFORMYLASE) >gi|2208948|emb|CAB09662.1| (Z96934) peptide deformylase [Clostridium beijerinckii]	gene	gene705	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0870
SPy_0872	SPy0872		SPy_0872	718482	720494	-	putative secreted 5'-nucleotidase	Best Blastp hit %3D emb|CAB88485.1| (AL353816) putative secreted 5'-nucleotidase [Streptomyces coelicolor A3(2)]	gene	gene706	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0872
SPy_0873	SPy0873		SPy_0873	720714	721364	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05604.1| (AP001513) unknown conserved protein [Bacillus halodurans]	gene	gene707	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0873
SPy_0874	SPy0874		SPy_0874	721367	722035	+	putative two-component response regulator	Best Blastp hit %3D dbj|BAB04091.1| (AP001508) two-component response regulator [Bacillus halodurans]	gene	gene708	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0874
SPy_0875	SPy0875		SPy_0875	722044	723276	+	putative two-component sensory transduction histidine kinase	Best Blastp hit %3D pir||S77016 sensory transduction histidine kinase sll0790 - Synechocystis sp. (strain PCC 6803) >gi|1001827|dbj|BAA10708.1| (D64005) sensory transduction histidine kinase [Synechocystis sp.]	gene	gene709	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0875
SPy_0876	SPy0876	mvaK1	mvaK1	723555	724448	+	mevalonate kinase	Best Blastp hit %3D gb|AAG02450.1|AF290097_1 (AF290097) mevalonate kinase [Streptococcus pyogenes]	gene	gene710	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0876
SPy_0877	SPy0877	mvaD	mvaD	724430	725374	+	mevalonate pyrophosphate decarboxylase	Best Blastp hit %3D gb|AAG02451.1|AF290097_2 (AF290097) mevalonate diphosphate decarboxylase [Streptococcus pyogenes]	gene	gene711	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0877
SPy_0878	SPy0878	mvaK2	mvaK2	725367	726374	+	phosphomevalonate kinase	Best Blastp hit %3D gb|AAG02452.1|AF290097_3 (AF290097) phosphomevalonate kinase [Streptococcus pyogenes]	gene	gene712	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0878
SPy_0879	SPy0879		SPy_0879	726367	727356	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07793.1| (AB037666) hypothetical protein [Streptomyces sp. CL190]	gene	gene713	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0879
SPy_0880	SPy0880	mvaS.1	mvaS.1	727586	728863	-	putative 3-hydroxy-3-methylglutaryl-coenzyme A	Best Blastp hit %3D gb|AAG02454.1|AF290098_2 (AF290098) HMG-CoA reductase [Streptococcus pneumoniae]	gene	gene714	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0880
SPy_0881	SPy0881	mvaS.2	mvaS.2	728850	730025	-	putative 3-hydroxy-3-methylglutaryl-coenzyme A synthase (HMG-CoA synthase)	Best Blastp hit %3D gb|AAG02453.1|AF290098_1 (AF290098) HMG-CoA synthase [Streptococcus pneumoniae]	gene	gene715	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0881
SPy_0882	SPy0882	thyA	thyA	730234	731073	+	putative thymidylate synthase	Best Blastp hit %3D sp|P19368|TYSY_LACLA THYMIDYLATE SYNTHASE (TS) (TSASE) >gi|280246|pir||A43797 thymidylate synthase (EC 2.1.1.45) - Lactococcus lactis subsp. lactis >gi|149513|gb|AAA25221.1| (M33770) thymidylate synthase (EC 2.1.1.45) [Lactococcus lactis]	gene	gene716	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0882
SPy_0883	SPy0883	dyr	dyr	731153	731650	+	putative dihydrofolate reductase	Best Blastp hit %3D gb|AAD35011.1|AF144418_1 (AF144418) dihydrofolate reductase [Streptococcus pneumoniae]	gene	gene717	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0883
SPy_0884	SPy0884		SPy_0884	731670	731840	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene718	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0884
SPy_0885	SPy0885	clpX	clpX	731970	733199	+	putative ATP-dependent Clp protease subunit X	Best Blastp hit %3D gb|AAF63738.1|AF236863_2 (AF236863) protease ClpX [Lactococcus lactis]	gene	gene719	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0885
SPy_0886	SPy0886		SPy_0886	733209	733808	+	conserved hypothetical GTP-binding protein	Best Blastp hit %3D gb|AAF63739.1|AF236863_3 (AF236863) hypothetical GTP-binding protein [Lactococcus lactis]	gene	gene720	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0886
SPy_0887	SPy0887		SPy_0887	733956	734699	+	hypothetical protein	Best Blastp hit %3D pir||S77180 glutamyl-tRNA reductase (EC 1.2.1.-) - Synechocystis sp. (strain PCC 6803) >gi|1652819|dbj|BAA17738.1| (D90908) transfer RNA-Gln reductase [Synechocystis sp.]	gene	gene721	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0887
SPy_0888	SPy0888	clpL	clpL	734757	736856	-	putative ATP-dependent Clp proteinase (ATP-binding subunit)	Best Blastp hit %3D sp|Q06716|CLPL_LACLA ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPL >gi|486816|pir||S35908 ATP-dependent Clp proteinase (EC 3.4.21.-) chain clpL - Lactococcus lactis subsp. lactis plasmid pUCL22 >gi|296464|emb|CAA44207.1| (X62333) ATPase [Lactococcus lactis]	gene	gene722	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0888
SPy_0889	SPy0889	rpiA	rpiA	737236	737919	+	putative ribose 5-phosphate isomerase	Best Blastp hit %3D sp|P72012|RPIA_METTH PROBABLE RIBOSE 5-PHOSPHATE ISOMERASE (PHOSPHORIBOISOMERASE) >gi|7450938|pir||G69180 ribose 5-phosphate isomerase - Methanobacterium thermoautotrophicum (strain Delta H) >gi|1669358|dbj|BAA13646.1| (D88555) orf2 [Methanobacterium thermoautotrophicum] >gi|2621688|gb|AAB85114.1| (AE000842) ribose 5-phosphate isomerase [Methanobacterium thermoautotrophicum]	gene	gene723	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0889
SPy_0890	SPy0890	deoB	deoB	737996	739207	+	putative phosphopentomutase	Best Blastp hit %3D sp|O32808|DEOB_LACLC PHOSPHOPENTOMUTASE (PHOSPHODEOXYRIBOMUTASE) >gi|2281308|gb|AAC45496.1| (U80410) phosphopentomutase [Lactococcus lactis subsp. cremoris]	gene	gene724	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0890
SPy_0891	SPy0891	arsC	arsC	739226	739666	+	putative arsenate reductase	Best Blastp hit %3D sp|P52147|ARC2_ECOLI ARSENATE REDUCTASE (ARSENICAL PUMP MODIFIER) >gi|1061418|gb|AAB09628.1| (U38947) ArsC [Plasmid R46]	gene	gene725	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0891
SPy_0892	SPy0892	punA	punA	739650	740459	+	putative purine nucleoside phosphorylase	Best Blastp hit %3D sp|P77834|PUNA_BACST PURINE NUCLEOSIDE PHOSPHORYLASE I (PNP I) (PU-NPASE I) (INOSINE PHOSPHORYLASE) >gi|2126870|pir||JT0873 purine-nucleoside phosphorylase (EC 2.4.2.1) - Bacillus stearothermophilus >gi|1638804|dbj|BAA13509.1| (D87959) purine nucleoside phosphorylase [Bacillus stearothermophilus]	gene	gene726	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0892
SPy_0894	SPy0894	deoD2	deoD2	741122	741835	+	putative purine nucleoside phosphorylase	Best Blastp hit %3D sp|Q56037|DEOD_STRTR PURINE NUCLEOSIDE PHOSPHORYLASE (INOSINE PHOSPHORYLASE) (PNP) >gi|1276873|gb|AAC44007.1| (U40830) DeoD [Streptococcus thermophilus] >gi|1588804|prf||2209356A deoD gene [Streptococcus thermophilus]	gene	gene727	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0894
SPy_0895	SPy0895		SPy_0895	741828	742616	+	histidine protein kinase	Best Blastp hit %3D gb|AAB81305.1| (L47121) histidine protein kinase [Carnobacterium piscicola]	gene	gene728	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0895
SPy_0898	SPy0898	cpsY	cpsY	742695	743600	-	putative transcriptional regulator	Best Blastp hit %3D emb|CAB36977.1| (Y17221) CpsY protein [Streptococcus agalactiae]	gene	gene729	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0898
SPy_0899	SPy0899		SPy_0899	743822	744358	+	hypothetical protein	Best Blastp hit %3D dbj|BAA82291.1| (AB028896) ORF1 [Streptococcus agalactiae]	gene	gene730	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0899
SPy_0900	SPy0900	pyrF	pyrF	744635	745327	+	putative orotidine-5'-decarboxylase PyrF	Best Blastp hit %3D sp|Q9ZHA7|DCOP_STRPN OROTIDINE 5'-PHOSPHATE DECARBOXYLASE (OMP DECARBOXYLASE) (OMPDCASE) >gi|4009483|gb|AAC95452.1| (AF068902) orotidine-5'-decarboxylase PyrF [Streptococcus pneumoniae]	gene	gene731	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0900
SPy_0901	SPy0901	pyrE	pyrE	745385	746014	+	putative orotate phosphoribosyltransferase	Best Blastp hit %3D gb|AAC95453.1| (AF068902) orotate phosphoribosyltransferase PyrE [Streptococcus pneumoniae]	gene	gene732	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0901
SPy_0902	SPy0902	amiC	amiC	746211	747665	+	putative amidase	Best Blastp hit %3D pir||C75543 6-aminohexanoate-cyclic-dimer hydrolase - Deinococcus radiodurans (strain R1) >gi|6457907|gb|AAF09821.1|AE001885_5 (AE001885) 6-aminohexanoate-cyclic-dimer hydrolase [Deinococcus radiodurans]	gene	gene733	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0902
SPy_0903	SPy0903		SPy_0903	747747	748646	+	putative ABC transporter (binding protein)	Best Blastp hit %3D sp|P42400|YCKB_BACSU PROBABLE ABC TRANSPORTER EXTRACELLULAR BINDING PROTEIN YCKB PRECURSOR (ORF2) >gi|7442312|pir||D69760 amino acid ABC transporter (binding protein) homolog yckB - Bacillus subtilis >gi|2632624|emb|CAB12132.1| (Z99105) similar to amino acid ABC transporter (binding protein) [Bacillus subtilis]	gene	gene734	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0903
SPy_0904	SPy0904		SPy_0904	748675	749325	+	putative ABC transporter (permease)	Best Blastp hit %3D sp|P42399|YCKA_BACSU PROBABLE AMINO-ACID ABC TRANSPORTER PERMEASE PROTEIN YCKA >gi|7442388|pir||C69760 amino acid ABC transporter (permease) homolog yckA - Bacillus subtilis >gi|710628|dbj|BAA06425.1| (D30762) homologue of glutamine permease of H. influenzae [Bacillus subtilis] >gi|1805409|dbj|BAA08971.1| (D50453) homologue of glutamine permease of H. inflenzae [Bacillus subtilis] >gi|2632623|emb|CAB12131.1| (Z99105) similar to amino acid ABC transporter (permease) [Bacillus subtilis]	gene	gene735	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0904
SPy_0905	SPy0905	ung	ung	749458	750111	+	putative uracil DNA glycosylase	Best Blastp hit %3D sp|Q9XDS8|UNG_STRAG URACIL-DNA GLYCOSYLASE (UDG) >gi|5381195|dbj|BAA82292.1| (AB028896) Uracil DNA glycosylase [Streptococcus agalactiae]	gene	gene736	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0905
SPy_0907	SPy0907	pyrC	pyrC	750243	751511	+	putative dihydroorotase	Best Blastp hit %3D sp|O66990|PYRC_AQUAE DIHYDROOROTASE (DHOASE) >gi|7435951|pir||C70370 dihydroorotase - Aquifex aeolicus >gi|2983361|gb|AAC06948.1| (AE000708) dihydroorotase [Aquifex aeolicus]	gene	gene737	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0907
SPy_0908	SPy0908		SPy_0908	751569	752210	-	hypothetical protein	Best Blastp hit %3D emb|CAB40549.1| (AJ236899) hypothetical protein [Streptococcus gordonii]	gene	gene738	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0908
SPy_0909	SPy0909	parE	parE	752342	754294	+	putative DNA topoisomerase IV (subunit B)	Best Blastp hit %3D emb|CAA91550.2| (Z67739) DNA topoisomerase IV [Streptococcus pneumoniae]	gene	gene739	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0909
SPy_0910	SPy0910	parC	parC	754385	756844	+	putative DNA topoisomerase IV (subunit C)	Best Blastp hit %3D gb|AAF63267.1| (AF220946) DNA topoisomerase IV subunit C [Streptococcus pyogenes]	gene	gene740	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0910
SPy_0911	SPy0911	bcaT	bcaT	756967	757989	+	putative branched-chain-amino-acid aminotransferase	Best Blastp hit %3D gb|AAF34406.1|AF164204_1 (AF164204) branched-chain amino acid aminotransferase [Lactococcus lactis subsp. cremoris] >gi|7620382|gb|AAF64593.1|AF169649_1 (AF169649) branched-chain aminotransferase IlvE [Lactococcus lactis]	gene	gene741	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0911
SPy_0912	SPy0912		SPy_0912	758053	758283	+	hypothetical protein	Best Blastp hit %3D gb|AAF19774.1|AF128451_1 (AF128451) repeat motif protein bdrA8 [Borrelia turicatae]	gene	gene742	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0912
SPy_0913	SPy0913		SPy_0913	758674	759879	+	putative ribosomal protein S1-like DNA-binding protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||JC4026 ribosomal protein S1-like DNA-binding protein - human	gene	gene745	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0913
SPy_0914	SPy0914		SPy_0914	760426	760728	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene747	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0914
SPy_0915	SPy0915		SPy_0915	760927	761913	+	hypothetical protein	Best Blastp hit %3D gb|AAB81912.1| (U92974) unknown [Lactococcus lactis]	gene	gene748	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0915
SPy_0916	SPy0916		SPy_0916	761984	762175	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene749	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0916
SPy_0917	SPy0917		SPy_0917	762224	762643	+	hypothetical protein	Best Blastp hit %3D sp|P39100|GT_ECOLI GLUTATHIONE S-TRANSFERASE >gi|1073395|pir||A55495 glutathione transferase (EC 2.5.1.18) - Escherichia coli >gi|4389382|pdb|1A0F|A Chain A%2C Crystal Structure Of Glutathione S-Transferase From Escherichia Coli Complexed With Glutathionesulfonic Acid >gi|4389383|pdb|1A0F|B Chain B%2C Crystal Structure Of Glutathione S-Transferase From Escherichia Coli Complexed With Glutathionesulfonic Acid >gi|1213565|dbj|BAA07509.1| (D38497) glutathione transferase [Escherichia coli] >gi|1742701|dbj|BAA15396.1| (D90807) Glutathione s-transferase (EC 2.5.1.18). [Escherichia coli] >gi|1787923|gb|AAC74707.1| (AE000259) glutathionine S-transferase [Escherichia coli]	gene	gene750	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0917
SPy_0918	SPy0918		SPy_0918	762880	763788	+	putative exfoliative toxin	Best Blastp hit %3D dbj|BAB08178.1| (AB036768) exfoliative toxin A [Staphylococcus hyicus]	gene	gene751	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0918
SPy_0919	SPy0919		SPy_0919	763906	764082	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene752	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0919
SPy_0921	SPy0921	miaA	miaA	764216	765115	+	putative tRNA isopentenylpyrophosphate transferase	Best Blastp hit %3D dbj|BAB06085.1| (AP001515) tRNA isopentenylpyrophosphate transferase [Bacillus halodurans]	gene	gene753	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0921
SPy_0922	SPy0922		SPy_0922	765188	766426	+	putative GTP-binding protein	Best Blastp hit %3D dbj|BAB06081.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene754	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0922
SPy_0923	SPy0923		SPy_0923	766419	767054	+	hypothetical protein	Best Blastp hit %3D gb|AAC63018.1| (AF082008) galactose-1-phosphate uridylyltransferase [Lactococcus lactis] >gi|4206188|gb|AAD11511.1| (U60828) galactose-1-phosphate uridylyltransferase [Lactococcus lactis]	gene	gene755	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0923
SPy_0924	SPy0924		SPy_0924	767069	767998	+	hypothetical protein	Best Blastp hit %3D sp|P54548|YQJK_BACSU HYPOTHETICAL 34.0 KDA PROTEIN IN GLNQ-ANSR INTERGENIC REGION >gi|7449474|pir||C69964 conserved hypothetical protein yqjK - Bacillus subtilis >gi|1303962|dbj|BAA12617.1| (D84432) YqjK [Bacillus subtilis] >gi|2634819|emb|CAB14316.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]	gene	gene756	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0924
SPy_0925	SPy0925		SPy_0925	767998	768762	+	putative oxidoreductase	Best Blastp hit %3D dbj|BAB05225.1| (AP001512) oxidoreductase [Bacillus halodurans]	gene	gene757	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0925
SPy_0926	SPy0926	recJ	recJ	768759	770969	+	putative single-strand DNA-specific exonuclease	Best Blastp hit %3D pir||H69980 single-strand DNA-specific exonuclease homolog yrvE - Bacillus subtilis >gi|2635226|emb|CAB14721.1| (Z99118) similar to single-strand DNA-specific exonuclease [Bacillus subtilis]	gene	gene758	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0926
SPy_0927	SPy0927	apt	apt	771120	771638	+	putative adenine phosphoribosyltransferase	Best Blastp hit %3D sp|O34443|APT_BACSU ADENINE PHOSPHORIBOSYLTRANSFERASE (APRT) >gi|7433925|pir||B69587 adenine phosphoribosyltransferase (EC 2.4.2.7) - Bacillus subtilis >gi|2580524|gb|AAC46040.1| (U86377) adenine phosphoribosyltransferase%3B Apt [Bacillus subtilis] >gi|2635225|emb|CAB14720.1| (Z99118) adenine phosphoribosyltransferase [Bacillus subtilis]	gene	gene759	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0927
SPy_0928	SPy0928		SPy_0928	771719	772402	+	hypothetical protein	Best Blastp hit %3D dbj|BAA11244.1| (D78182) ORF2 [Streptococcus mutans]	gene	gene760	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0928
SPy_0929	SPy0929	nth	nth	772399	773055	+	putative endonuclease III (DNA repair)	Best Blastp hit %3D dbj|BAB05417.1| (AP001512) endonuclease III (DNA repair) [Bacillus halodurans]	gene	gene761	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0929
SPy_0930	SPy0930		SPy_0930	773127	773813	+	hypothetical protein	Best Blastp hit %3D dbj|BAA11245.1| (D78182) ORF3 [Streptococcus mutans]	gene	gene762	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0930
SPy_0931	SPy0931		SPy_0931	773803	774591	+	hypothetical protein	Best Blastp hit %3D dbj|BAA11246.1| (D78182) ORF4 [Streptococcus mutans]	gene	gene763	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0931
SPy_0932	SPy0932		SPy_0932	774631	775737	+	putative oxidoreductase	Best Blastp hit %3D sp|O32159|YURR_BACSU HYPOTHETICAL 39.4 KD OXIDOREDUCTASE IN HOM-MRGA INTERGENIC REGION >gi|7475684|pir||A70019 opine catabolism homolog yurR - Bacillus subtilis >gi|2635760|emb|CAB15253.1| (Z99120) similar to opine catabolism [Bacillus subtilis]	gene	gene764	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0932
SPy_0933	SPy0933	cpsFO	cpsFO	775795	776664	+	glucose-1-phosphate thymidyl transferase	Best Blastp hit %3D gb|AAC38757.1| (AF030373) glucose-1-phosphate thymidyl transferase [Streptococcus pneumoniae] >gi|3818496|gb|AAC69538.1| (AF057294) Cps23fO [Streptococcus pneumoniae]	gene	gene765	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0933
SPy_0935	SPy0935	cpsFP	cpsFP	776664	777257	+	putative dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase	Best Blastp hit %3D gb|AAC44970.1| (U09239) dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase [Streptococcus pneumoniae] >gi|2804690|gb|AAC38678.1| (AF030360) dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase [Streptococcus pneumoniae] >gi|2804696|gb|AAC38683.1| (AF030361) dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase [Streptococcus pneumoniae] >gi|2804703|gb|AAC38689.1| (AF030362) dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase [Streptococcus pneumoniae] >gi|2804715|gb|AAC38699.1| (AF030364) dTDP-4-keto-6-deoxyglucose-3%2C5-epimerase [Streptococcus pneumoniae]	gene	gene766	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0935
SPy_0936	SPy0936	cpsFQ	cpsFQ	777501	778541	+	putative dTDP-glucose-4%2C6-dehydratase	Best Blastp hit %3D sp|P95780|RMLB_STRMU DTDP-GLUCOSE 4%2C6-DEHYDRATASE >gi|1813347|dbj|BAA11249.1| (D78182) dTDP-glucose-4%2C6-dehydratase [Streptococcus mutans]	gene	gene767	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0936
SPy_0937	SPy0937	int3	int3	778635	779774	-	putative integrase - phage associated	Best Blastp hit %3D emb|CAB96616.1| (AJ400629) integrase [Streptococcus pneumoniae bacteriophage MM1]	gene	gene768	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0937
SPy_0938	SPy0938		SPy_0938	780028	780837	-	hypothetical protein	Best Blastp hit %3D gb|AAC35448.1| (AF022481) possible plasmid partition protein%3B GTG probable start codon%3B orf3 [Borrelia burgdorferi] >gi|6382193|gb|AAF07509.1|AE001577_23 (AE001577) conserved hypothetical protein [Borrelia burgdorferi]	gene	gene769	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0938
SPy_0939	SPy0939		SPy_0939	780850	781596	-	putative repressor protein - phage associated	Best Blastp hit %3D gi|9635682 repressor [Staphylococcus aureus prophage phiPV83] >gi|8918752|dbj|BAA97812.1| (AB044554) repressor [Staphylococcus aureus prophage phiPV83]	gene	gene770	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0939
SPy_0940	SPy0940		SPy_0940	781786	781944	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene771	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0940
SPy_0942	SPy0942		SPy_0942	782123	782962	-	hypothetical protein	Best Blastp hit %3D pir||T18372 repeat organellar protein - Plasmodium chabaudi >gi|1151158|gb|AAC63403.1| (U43145) repeat organellar protein [Plasmodium chabaudi]	gene	gene772	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0942
SPy_0943	SPy0943		SPy_0943	783022	783162	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene773	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0943
SPy_0944	SPy0944		SPy_0944	783080	783307	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene774	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0944
SPy_0945	SPy0945		SPy_0945	783381	783587	+	hypothetical protein	Best Blastp hit %3D gb|AAB18679.1| (U38906) tec gene product [Bacteriophage r1t]	gene	gene775	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0945
SPy_0946	SPy0946		SPy_0946	783627	784355	+	putative P1-type antirepressor - phage associated	Best Blastp hit %3D gb|AAC03459.1| (AF020798) P1-antirepressor homolog [Streptococcus thermophilus bacteriophage TP-J34]	gene	gene776	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0946
SPy_0947	SPy0947		SPy_0947	784387	784653	+	hypothetical protein	Best Blastp hit %3D sp|O13764|PEX6_SCHPO PROBABLE PEROXIN-6 >gi|7492793|pir||T37816 probable peroxin-6%2C AAA family atpase - fission yeast (Schizosaccharomyces pombe) >gi|2370473|emb|CAB11501.1| (Z98849) putative peroxin-6%2C AAA family atpase [Schizosaccharomyces pombe]	gene	gene777	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0947
SPy_0948	SPy0948		SPy_0948	784588	785394	-	hypothetical protein	Best Blastp hit %3D emb|CAB83727.1| (AL162753) conserved hypothetical protein [Neisseria meningitidis]	gene	gene778	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0948
SPy_0949	SPy0949		SPy_0949	785536	785772	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene779	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0949
SPy_0951	SPy0951		SPy_0951	785915	786222	+		This gene contains a sequence confirmed frameshift mutation at the N-terminus resulting in the ATG and RBS being out of frame with the remainder of the gene.%3B Best Blastp hit %3D gb|AAC98430.1| (L29324) excisionase [Streptococcus pneumoniae]	gene	gene780	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0951
SPy_0952	SPy0952		SPy_0952	786224	786409	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene781	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0952
SPy_0953	SPy0953		SPy_0953	786892	787278	+	hypothetical protein	Best Blastp hit %3D dbj|BAA22163.1| (AB006752) ORF1 [Streptococcus pyogenes]	gene	gene782	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0953
SPy_0954	SPy0954		SPy_0954	787259	787492	+	hypothetical protein	Best Blastp hit %3D pir||B72386 hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4980857|gb|AAD35441.1|AE001716_4 (AE001716) hypothetical protein [Thermotoga maritima]	gene	gene783	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0954
SPy_0956	SPy0956		SPy_0956	787638	787844	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene784	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0956
SPy_0957	SPy0957		SPy_0957	787900	788229	+	hypothetical protein	Best Blastp hit %3D gb|AAF03365.1|AF149924_1 (AF149924) chaperonin beta subunit [Sulfolobus acidocaldarius]	gene	gene785	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0957
SPy_0958	SPy0958		SPy_0958	788232	789023	+	hypothetical protein	Best Blastp hit %3D gb|AAF43118.1|AF208055_5 (AF208055) Orf245 [bacteriophage phi31.1] >gi|8248141|gb|AAF74061.1| (AF212844) ORF245 [Lactococcus lactis] >gi|8248177|gb|AAF74095.1| (AF212846) ORF245 [Lactococcus lactis bacteriophage ul36.1] >gi|8248193|gb|AAF74110.1| (AF212847) ORF245 [Lactococcus lactis bacteriophage ul36.2]	gene	gene786	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0958
SPy_0959	SPy0959		SPy_0959	789033	789698	+	hypothetical protein	Best Blastp hit %3D gb|AAF43119.1|AF208055_6 (AF208055) Orf364 [bacteriophage phi31.1] >gi|8248142|gb|AAF74062.1| (AF212844) ORF364 [Lactococcus lactis] >gi|8248178|gb|AAF74096.1| (AF212846) ORF364 [Lactococcus lactis bacteriophage ul36.1] >gi|8248194|gb|AAF74111.1| (AF212847) ORF364 [Lactococcus lactis bacteriophage ul36.2]	gene	gene787	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0959
SPy_0960	SPy0960		SPy_0960	789702	790061	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene788	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0960
SPy_0961	SPy0961		SPy_0961	790257	790595	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene789	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0961
SPy_0962	SPy0962		SPy_0962	790592	791104	+	hypothetical protein	Best Blastp hit %3D gb|AAC63027.1| (AF087814) M3 [bacteriophage 712]	gene	gene790	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0962
SPy_0963	SPy0963		SPy_0963	791282	791527	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene791	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0963
SPy_0965	SPy0965		SPy_0965	791579	792040	+	hypothetical protein	Best Blastp hit %3D emb|CAB53841.1| (AJ242593) gp51 [Bacteriophage A118]	gene	gene792	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0965
SPy_0967	SPy0967		SPy_0967	792490	792930	+	hypothetical protein	Best Blastp hit %3D gi|9635007 gp137 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7523568|gb|AAF63071.1|AF158600_26 (AF158600) gp137 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene793	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0967
SPy_0968	SPy0968		SPy_0968	793245	794159	+	hypothetical protein	Best Blastp hit %3D gi|9964487 AMV173 [Amsacta moorei entomopoxvirus] >gi|9944696|gb|AAG02879.1|AF250284_173 (AF250284) AMV173 [Amsacta moorei entomopoxvirus]	gene	gene794	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0968
SPy_0970	SPy0970		SPy_0970	794178	794639	+	hypothetical protein	Best Blastp hit %3D pir||B70367 hypothetical protein aq_765 - Aquifex aeolicus >gi|2983337|gb|AAC06926.1| (AE000706) putative protein [Aquifex aeolicus]	gene	gene795	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0970
SPy_0971	SPy0971		SPy_0971	794667	795149	+	putative terminase%2C small subunit - phage associated	Best Blastp hit %3D pir||T13203 probable terminase - Lactobacillus phage phi-gle >gi|1926347|emb|CAA66779.1| (X98106) Rorf172 [Bacteriophage phig1e]	gene	gene796	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0971
SPy_0972	SPy0972		SPy_0972	795127	796416	+	putative terminase%2C large subunit - phage associated	Best Blastp hit %3D sp|P54308|TERL_BPSPP TERMINASE LARGE SUBUNIT (G2P) >gi|93748|pir||S24451 terminase - phage SPP1 >gi|7461905|pir||T42263 hypothetical protein - phage SPP1 >gi|15466|emb|CAA39537.1| (X56064) terminase [Bacteriophage SPP1] >gi|2764840|emb|CAA66573.1| (X97918) gene 2 [Bacteriophage SPP1]	gene	gene797	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0972
SPy_0973	SPy0973		SPy_0973	796428	797927	+		This gene contains a sequence confirmed point mutation within the coding region	gene	gene798	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0973
SPy_0975	SPy0975		SPy_0975	797911	799536	+	hypothetical protein	Best Blastp hit %3D pir||T13317 hypothetical protein 28 - Streptococcus phage phi-O1205 >gi|2444107|gb|AAC79543.1| (U88974) ORF28 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene799	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0975
SPy_0976	SPy0976		SPy_0976	799527	799706	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene800	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0976
SPy_0977	SPy0977		SPy_0977	799766	800035	+	hypothetical protein	Best Blastp hit %3D pir||T39494 kinesin-like protein - fission yeast (Schizosaccharomyces pombe) >gi|4376084|emb|CAA22353.1| (AL034433) kinesin-like protein [Schizosaccharomyces pombe]	gene	gene801	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0977
SPy_0978	SPy0978		SPy_0978	800125	800295	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene802	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0978
SPy_0979	SPy0979		SPy_0979	800424	800672	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene803	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0979
SPy_0980	SPy0980		SPy_0980	800674	801420	+	putative antirepressor - phage associated	Best Blastp hit %3D emb|CAA73339.1| (Y12813) hypothetical protein [Lactobacillus casei bacteriophage A2] >gi|6599316|emb|CAB63662.1| (AJ251789) putative antirepressor [Lactobacillus casei bacteriophage A2]	gene	gene804	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0980
SPy_0981	SPy0981		SPy_0981	801532	802065	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07248.1| (AP001519) unknown [Bacillus halodurans]	gene	gene805	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0981
SPy_0982	SPy0982		SPy_0982	802075	802455	+	putative structural protein - phage associated	Best Blastp hit %3D pir||T13319 probable structural protein - Streptococcus phage phi-O1205 >gi|2444109|gb|AAC79545.1| (U88974) ORF30 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene806	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0982
SPy_0984	SPy0984		SPy_0984	802458	803507	+	hypothetical protein	Best Blastp hit %3D pir||T13320 hypothetical protein 31 - Streptococcus phage phi-O1205 >gi|2444110|gb|AAC79546.1| (U88974) ORF31 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene807	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0984
SPy_0985	SPy0985		SPy_0985	803519	803785	+	hypothetical protein	Best Blastp hit %3D gi|9635016 gp53 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7517702|pir||T13626 hypothetical protein gp53 - Streptococcus phage phi-Sfi11 >gi|3320439|gb|AAC34403.1| (AF158600) gp53 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene808	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0985
SPy_0986	SPy0986		SPy_0986	803797	804150	+	hypothetical protein	Best Blastp hit %3D gi|9635017 gp113 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7517690|pir||T13627 hypothetical protein gp113 - Streptococcus phage phi-Sfi11 >gi|3320440|gb|AAC34404.1| (AF158600) gp113 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene809	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0986
SPy_0987	SPy0987		SPy_0987	804147	804455	+	conserved hypothetical protein - phage 370.2 protein	Best Blastp hit %3D emb|CAA59188.1| (X84706) b3 [Bacteriophage B1]	gene	gene810	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0987
SPy_0988	SPy0988		SPy_0988	804436	804801	+	hypothetical protein	Best Blastp hit %3D gi|9635019 gp114 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7515256|pir||T13324 hypothetical protein 35 - Streptococcus phage phi-O1205 >gi|7517691|pir||T13629 hypothetical protein gp114 - Streptococcus phage phi-Sfi11 >gi|2444114|gb|AAC79550.1| (U88974) ORF35 [Streptococcus thermophilus temperate bacteriophage O1205] >gi|3320442|gb|AAC34406.1| (AF158600) gp114 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene811	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0988
SPy_0989	SPy0989		SPy_0989	804798	805187	+	hypothetical protein	Best Blastp hit %3D emb|CAA59190.1| (X84706) x [Bacteriophage B1]	gene	gene812	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0989
SPy_0991	SPy0991		SPy_0991	805284	805850	+	putative structural protein - phage associated	Best Blastp hit %3D gb|AAA32613.1| (L31366) structural protein [Bacteriophage Tuc2009]	gene	gene813	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0991
SPy_0992	SPy0992		SPy_0992	805910	806263	+	hypothetical protein	Best Blastp hit %3D emb|CAA59192.1| (X84706) a2 [Bacteriophage B1]	gene	gene814	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0992
SPy_0993	SPy0993		SPy_0993	806305	806634	+	hypothetical protein	Best Blastp hit %3D emb|CAA59193.1| (X84706) c2 [Bacteriophage B1]	gene	gene815	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0993
SPy_0994	SPy0994		SPy_0994	806649	810284	+	putative minor tail protein - phage associated	Best Blastp hit %3D gi|9635024 putative minor tail protein [Streptococcus thermophilus bacteriophage Sfi11] >gi|7521218|pir||T13634 probable minor tail protein gp1510 - Streptococcus phage phi-Sfi11 >gi|3540284|gb|AAC34411.1| (AF158600) putative minor tail protein [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene816	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0994
SPy_0995	SPy0995		SPy_0995	810317	811096	+	hypothetical protein	Best Blastp hit %3D pir||T42299 hypothetical protein 19.1 - phage SPP1 >gi|2764876|emb|CAA66560.1| (X97918) gene 19.1 [Bacteriophage SPP1]	gene	gene817	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0995
SPy_0996	SPy0996		SPy_0996	811093	813141	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene818	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0996
SPy_0997	SPy0997	hylP2	hylP2	813141	814259	+	hyaluronidase - phage associated	Best Blastp hit %3D sp|P15316|HYAL_BPH44 HYALURONOGLUCOSAMINIDASE (HYALURONIDASE) >gi|67500|pir||HUBPHA hyaluronoglucosaminidase (EC 3.2.1.35) - Streptococcus pyogenes phage H4489A >gi|215053|gb|AAA98101.1| (M19348) hyaluronidase [Streptococcus pyogenes phage H4489A]	gene	gene819	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0997
SPy_0998	SPy0998		SPy_0998	814272	816182	+	hypothetical protein	Best Blastp hit %3D sp|P15317|YHYA_BPH44 HYPOTHETICAL 65 KD PROTEIN IN HYALURONIDASE REGION >gi|76370|pir||B30566 hypothetical protein - Streptococcus pyogenes phage H4489A >gi|215054|gb|AAA98102.1| (M19348) ORF [Streptococcus pyogenes phage H4489A]	gene	gene820	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0998
SPy_0999	SPy0999		SPy_0999	816196	816357	+	hypothetical protein	Best Blastp hit %3D dbj|BAB13391.1| (AB046785) KIAA1565 protein [Homo sapiens]	gene	gene821	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_0999
SPy_1001	SPy1001		SPy_1001	816360	816971	+	hypothetical protein	Best Blastp hit %3D pir||T13336 hypothetical protein 47 - Streptococcus phage phi-O1205 >gi|2444126|gb|AAC79562.1| (U88974) ORF47 [Streptococcus thermophilus temperate bacteriophage O1205]	gene	gene822	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1001
SPy_1002	SPy1002		SPy_1002	816982	817278	+	hypothetical protein	Best Blastp hit %3D gi|6324790 involved in secretion%3B Rud3p [Saccharomyces cerevisiae] >gi|2132085|pir||S60943 RUD3 protein - yeast (Saccharomyces cerevisiae) >gi|1050768|emb|CAA63179.1| (X92441) YOR50-6 [Saccharomyces cerevisiae] >gi|1420503|emb|CAA99433.1| (Z75124) ORF YOR216c [Saccharomyces cerevisiae]	gene	gene823	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1002
SPy_1006	SPy1006	lys	lys	817572	818906	+	putative lysin - phage associated	Best Blastp hit %3D gb|AAF72807.1|AF186180_1 (AF186180) 49.7 kDa protein [Streptococcus equi]	gene	gene824	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1006
SPy_1007	SPy1007	speI	speI	819180	819857	+	streptococcal exotoxin I	Best Blastp hit %3D gb|AAF72808.1|AF186180_2 (AF186180) 25.7 kDa protein [Streptococcus equi]	gene	gene825	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1007
SPy_1008	SPy1008	speH	speH	819883	820593	+	streptococcal exotoxin H precursor	Best Blastp hit %3D gb|AAD30989.1|AF124500_1 (AF124500) exotoxin H precursor [Streptococcus pyogenes]	gene	gene826	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1008
SPy_1010	SPy1010	mutX	mutX	821197	821673	+	putative 7%2C8-dihydro-8-oxoguanine-triphosphatase	Best Blastp hit %3D sp|P95781|MUTX_STRMU MUTATOR MUTT PROTEIN (7%2C8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASE) (8-OXO-DGTPASE) (DGTP PYROPHOSPHOHYDROLASE) >gi|1813348|dbj|BAA11250.1| (D78182) MutX [Streptococcus mutans]	gene	gene827	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1010
SPy_1011	SPy1011		SPy_1011	821731	822912	+	hypothetical protein	Best Blastp hit %3D gb|AAD00285.1| (U78604) putative membrane protein [Streptococcus mutans]	gene	gene828	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1011
SPy_1012	SPy1012		SPy_1012	822902	824149	+	hypothetical protein	Best Blastp hit %3D gb|AAA25160.1| (L16975) ORF1 [Lactococcus lactis]	gene	gene829	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1012
SPy_1013	SPy1013	fbp	fbp	824208	825860	-	putative fibronectin-binding protein-like protein A	Best Blastp hit %3D emb|CAA46282.1| (X65164) fibronectin-binding protein-like protein A [Streptococcus gordonii]	gene	gene830	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1013
SPy_1016	SPy1016		SPy_1016	826214	827212	+	hypothetical protein	Best Blastp hit %3D gb|AAF94260.1| (AE004191) conserved hypothetical protein [Vibrio cholerae]	gene	gene831	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1016
SPy_1017	SPy1017		SPy_1017	827217	827381	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene832	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1017
SPy_1018	SPy1018		SPy_1018	827558	828427	+	putative ABC transport protein (permease)	Best Blastp hit %3D gb|AAG07224.1|AE004801_2 (AE004801) probable permease of ABC transporter [Pseudomonas aeruginosa]	gene	gene833	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1018
SPy_1019	SPy1019		SPy_1019	828424	829182	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAF86640.1|AF162694_1 (AF162694) ABC transporter [Enterococcus gallinarum]	gene	gene834	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1019
SPy_1020	SPy1020		SPy_1020	829386	831047	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06117.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene835	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1020
SPy_1022	SPy1022	estA	estA	831180	831965	+	putative tributyrin esterase	Best Blastp hit %3D gb|AAF62859.1|AF157484_1 (AF157484) tributyrin esterase [Lactococcus lactis subsp. lactis]	gene	gene836	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1022
SPy_1024	SPy1024		SPy_1024	831995	832321	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene837	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1024
SPy_1025	SPy1025		SPy_1025	832367	834274	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|O05519|YDIF_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YDIF >gi|7445765|pir||G69786 ABC transporter (ATP-binding protein) homolog ydiF - Bacillus subtilis >gi|1945111|dbj|BAA19719.1| (D88802) H. influenzae hypothetical ABC transporter%3B P44808 (974) [Bacillus subtilis] >gi|2632908|emb|CAB12414.1| (Z99107) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene838	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1025
SPy_1026	SPy1026	acoA	acoA	834559	835527	+	putative acetoin dehydrogenase (TPP-dependent) alpha chain	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB04495.1| (AP001509) acetoin dehydrogenase (TPP-dependent) alpha chain [Bacillus halodurans]	gene	gene839	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1026
SPy_1028	SPy1028	acoB	acoB	835586	836584	+	putative acetoin dehydrogenase (TPP-dependent) beta chain	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB04496.1| (AP001509) acetoin dehydrogenase (TPP-dependent) beta chain [Bacillus halodurans]	gene	gene840	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1028
SPy_1029	SPy1029	acoC	acoC	836769	838178	+	putative dihydrolipoamide S-acetyltransferase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB04497.1| (AP001509) dihydrolipoamide S-acetyltransferase [Bacillus halodurans]	gene	gene841	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1029
SPy_1031	SPy1031	acoL	acoL	838505	840268	+	putative dihydrolipoamide dehydrogenase%2C component E3	Best Blastp hit %3D pir||I40794 dihydrolipoamide dehydrogenase (EC 1.8.1.4) - Clostridium magnum >gi|472330|gb|AAA21748.1| (L31844) dihydrolipoamide dehydrogenase [Clostridium magnum]	gene	gene842	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1031
SPy_1032	SPy1032	hylA	hylA	840942	843359	-	extracellular hyaluronate lyase	Best Blastp hit %3D sp|Q54873|HYSA_STRPN HYALURONATE LYASE PRECURSOR (HYALURONIDASE) (HYASE) >gi|437705|gb|AAA53685.1| (L20670) hyaluronidase [Streptococcus pneumoniae]	gene	gene843	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1032
SPy_1033	SPy1033		SPy_1033	843592	844581	+	putative lipoate-protein ligase	Best Blastp hit %3D dbj|BAB04402.1| (AP001509) lipoate-protein ligase [Bacillus halodurans]	gene	gene844	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1033
SPy_1034	SPy1034		SPy_1034	844690	845481	-	hypothetical protein	Best Blastp hit %3D pir||S74821 hypothetical protein slr1742 - Synechocystis sp. (strain PCC 6803) >gi|1652864|dbj|BAA17782.1| (D90909) hypothetical protein [Synechocystis sp.]	gene	gene845	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1034
SPy_1035	SPy1035		SPy_1035	845481	846818	-	putative UDP-N-acetylmuramyl tripeptide synthetase	Best Blastp hit %3D pir||S76138 hypothetical protein slr0938 - Synechocystis sp. (strain PCC 6803) >gi|1653484|dbj|BAA18397.1| (D90914) hypothetical protein [Synechocystis sp.]	gene	gene846	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1035
SPy_1036	SPy1036		SPy_1036	846931	847782	+	hypothetical protein	Best Blastp hit %3D dbj|BAB03984.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene847	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1036
SPy_1037	SPy1037		SPy_1037	847779	848735	+	hypothetical protein	Best Blastp hit %3D pir||A69745 hypothetical protein ybbR - Bacillus subtilis >gi|2632443|emb|CAB11952.1| (Z99104) ybbR [Bacillus subtilis] >gi|2632461|emb|CAB11969.1| (Z99105) ybbR [Bacillus subtilis]	gene	gene848	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1037
SPy_1038	SPy1038		SPy_1038	848789	850144	+	putative phospho-sugar mutase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||B69745 phosphoglucomutase (glycolysis) homolog ybbT - Bacillus subtilis >gi|2632444|emb|CAB11953.1| (Z99104) similar to phosphoglucomutase (glycolysis) [Bacillus subtilis] >gi|2632462|emb|CAB11970.1| (Z99105) similar to phosphoglucomutase (glycolysis) [Bacillus subtilis]	gene	gene849	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1038
SPy_1039	SPy1039		SPy_1039	850278	850919	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene850	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1039
SPy_1040	SPy1040	hemN	hemN	850982	852112	+	putative coproporphyrinogen III oxidase	Best Blastp hit %3D pir||B69640 coproporphyrinogen oxidase (EC 1.3.3.3) III%2C oxygen-independent hemN - Bacillus subtilis >gi|1303805|dbj|BAA12461.1| (D84432) YqeR [Bacillus subtilis] >gi|2634996|emb|CAB14492.1| (Z99117) coproporphyrinogen III oxidase [Bacillus subtilis]	gene	gene851	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1040
SPy_1042	SPy1042		SPy_1042	852306	852875	+	hypothetical protein	Best Blastp hit %3D gb|AAB71730.1| (U65643) acyl-ACP thioesterase [Myristica fragrans]	gene	gene852	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1042
SPy_1043	SPy1043		SPy_1043	852875	853639	+	hypothetical protein	Best Blastp hit %3D pir||H70023 N-acetyl-glucosamine catabolism homolog yutF - Bacillus subtilis >gi|2635726|emb|CAB15219.1| (Z99120) similar to N-acetyl-glucosamine catabolism [Bacillus subtilis]	gene	gene853	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1043
SPy_1044	SPy1044		SPy_1044	853639	854271	+	hypothetical protein	Best Blastp hit %3D sp|P54589|YHCE_BACSU HYPOTHETICAL 29.5 KD PROTEIN IN GLPD-CSPB INTERGENIC REGION >gi|7475050|pir||A69822 hypothetical protein yhcE - Bacillus subtilis >gi|1239980|emb|CAA65688.1| (X96983) hypothetical protein [Bacillus subtilis] >gi|2633228|emb|CAB12733.1| (Z99108) yhcE [Bacillus subtilis]	gene	gene854	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1044
SPy_1046	SPy1046		SPy_1046	854751	858857	+	hypothetical protein	Best Blastp hit %3D pir||H81982 hypothetical protein NMA0631 [imported] - Neisseria meningitidis (group A strain Z2491) >gi|7379363|emb|CAB83920.1| (AL162753) hypothetical protein NMA0631 [Neisseria meningitidis]	gene	gene855	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1046
SPy_1047	SPy1047		SPy_1047	858857	859726	+	hypothetical protein	Best Blastp hit %3D pir||E81299 hypothetical protein Cj1522c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968946|emb|CAB73942.1| (AL139078) hypothetical protein Cj1522c [Campylobacter jejuni]	gene	gene856	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1047
SPy_1048	SPy1048		SPy_1048	859723	860064	+	hypothetical protein	Best Blastp hit %3D emb|CAB83918.1| (AL162753) hypothetical protein NMA0629 [Neisseria meningitidis]	gene	gene857	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1048
SPy_1049	SPy1049		SPy_1049	860054	860716	+	hypothetical protein	Best Blastp hit %3D pir||T03910 UDP-glucuronosyltransferase homolog F39G3.1 - Caenorhabditis elegans >gi|2291205|gb|AAB65327.1| (AF016424) Similar to UDP-glucosyltransferase [Caenorhabditis elegans]	gene	gene858	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1049
SPy_1052	SPy1052		SPy_1052	861363	861770	+		This gene has several point mutations resulting in the introduction of stop codons within the coding region.%3B Best Blastp hit %3D pir||F75266 nucleoside diphosphate kinase - Deinococcus radiodurans (strain R1) >gi|6460321|gb|AAF12041.1|AE002079_6 (AE002079) nucleoside diphosphate kinase [Deinococcus radiodurans]	gene	gene859	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1052
SPy_1053	SPy1053	lepA	lepA	861894	863726	+	GTP-binding protein	Best Blastp hit %3D sp|P37949|LEPA_BACSU GTP-BINDING PROTEIN LEPA >gi|7443610|pir||G69649 GTP-binding protein lepA - Bacillus subtilis >gi|1122398|emb|CAA62842.1| (X91655) lepA [Bacillus subtilis] >gi|1303804|dbj|BAA12460.1| (D84432) YqeQ [Bacillus subtilis] >gi|2634997|emb|CAB14493.1| (Z99117) GTP-binding protein [Bacillus subtilis]	gene	gene860	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1053
SPy_1054	SPy1054		SPy_1054	863973	864854	+	putative collagen-like protein	Definite frame shift - see blast%3B Best Blastp hit %3D gb|AAF81278.1|AF252861_1 (AF252861) collagen-like protein Scl [Streptococcus pyogenes]	gene	gene861	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1054
SPy_1055	SPy1055	csrA	csrA	865040	865477	+	putative heavy metal stress response protein	Best Blastp hit %3D emb|CAB46979.1| (AJ243482) CSRA protein [Enterococcus faecalis]	gene	gene862	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1055
SPy_1056	SPy1056		SPy_1056	865592	866611	+	hypothetical protein	Best Blastp hit %3D sp|P33019|YEIH_ECOLI HYPOTHETICAL 36.9 KD PROTEIN IN LYSP-NFO INTERGENIC REGION >gi|7465981|pir||E64984 hypothetical 36.9 kD protein in lysP-nfo intergenic region - Escherichia coli (strain K-12) >gi|405879|gb|AAA60511.1| (U00007) yeiH [Escherichia coli] >gi|1788482|gb|AAC75219.1| (AE000305) orf%2C hypothetical protein [Escherichia coli] >gi|744193|prf||2014253BD yeiH gene [Escherichia coli]	gene	gene863	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1056
SPy_1057	SPy1057		SPy_1057	866818	867243	+	hypothetical protein	Best Blastp hit %3D gb|AAF81086.1|AF228498_6 (AF228498) AgaF [Escherichia coli]	gene	gene864	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1057
SPy_1058	SPy1058		SPy_1058	867262	867753	+	putative phosphotransferase system (PTS)%2C enzyme II component B	Best Blastp hit %3D sp|P37081|PTRB_KLEPN PTS SYSTEM%2C SORBOSE-SPECIFIC IIB COMPONENT (EIIB-SOR) (SORBOSE-PERMEASE IIB COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C B COMPONENT) (EIII-B-SOR) >gi|1073644|pir||S50188 phosphotransferase system enzyme II component B%2C sorbose-specific - Klebsiella pneumoniae >gi|43941|emb|CAA46858.1| (X66059) EIII-B Sor PTS [Klebsiella pneumoniae] >gi|1091868|prf||2022173D sorB gene [Klebsiella pneumoniae]	gene	gene865	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1058
SPy_1059	SPy1059		SPy_1059	867788	868579	+	putative phospotransferase system (PTS)%2C enzyme II%2C component C	Best Blastp hit %3D gb|AAF81091.1|AF228498_11 (AF228498) AgaC [Escherichia coli]	gene	gene866	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1059
SPy_1060	SPy1060		SPy_1060	868576	869403	+	putative phospotransferase system (PTS)%2C enzyme II component D	Best Blastp hit %3D sp|P08188|PTND_ECOLI PTS SYSTEM%2C MANNOSE-SPECIFIC IID COMPONENT (EIID-MAN) (MANNOSE-PERMEASE IID COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C D COMPONENT) (EII-M-MAN) >gi|66860|pir||WQECMM phosphotransferase system enzyme II (EC 2.7.1.69)%2C mannose-specific%2C factor IID - Escherichia coli >gi|147404|gb|AAA24445.1| (J02699) mannose permease subunit II-M-Man [Escherichia coli] >gi|1736464|dbj|BAA15631.1| (D90826) PTS system%2C Mannose-specific IID component (EIID-MAN) (Mannose- permease IID component) (Phosphotransferase enzyme II%2C D component) (EII-M-MAN). [Escherichia coli] >gi|1788122|gb|AAC74889.1| (AE000276) PTS enzyme IID%2C mannose-specific [Escherichia coli]	gene	gene867	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1060
SPy_1061	SPy1061		SPy_1061	869539	871188	+	putative two-component sensor histidine kinase	Best Blastp hit %3D dbj|BAB07166.1| (AP001518) two-component sensor histidine kinase [Bacillus halodurans]	gene	gene868	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1061
SPy_1062	SPy1062		SPy_1062	871192	871980	+	putative two-component response regulator	Best Blastp hit %3D emb|CAB54580.1| (AJ006398) response regulator [Streptococcus pneumoniae] >gi|6911255|gb|AAF31452.1|AF221126_1 (AF221126) putative response regulator [Streptococcus pneumoniae]	gene	gene869	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1062
SPy_1063	SPy1063		SPy_1063	872049	873020	+	putative periplasmic-iron-binding protein	Best Blastp hit %3D gb|AAD18094.2| (U75349) periplasmic-iron-binding protein BitA [Brachyspira hyodysenteriae]	gene	gene870	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1063
SPy_1064	SPy1064		SPy_1064	873117	873464	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene871	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1064
SPy_1065	SPy1065		SPy_1065	873799	874365	+	putative acetyltransferase	Best Blastp hit %3D dbj|BAB03334.1| (AB035451) hypothetical protein [Staphylococcus aureus]	gene	gene872	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1065
SPy_1066	SPy1066		SPy_1066	874369	875070	+	hypothetical protein	Best Blastp hit %3D pir||E69814 conserved hypothetical protein yfnB - Bacillus subtilis >gi|2116760|dbj|BAA20111.1| (D86418) YfnB [Bacillus subtilis] >gi|2633046|emb|CAB12552.1| (Z99107) similar to hypothetical proteins [Bacillus subtilis] >gi|2633057|emb|CAB12562.1| (Z99108) similar to hypothetical proteins [Bacillus subtilis]	gene	gene873	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1066
SPy_1067	SPy1067	gabD	gabD	875165	876562	+	putative succinic semialdehyde dehydrogenase	Best Blastp hit %3D gb|AAD19405.1| (AF102543) succinic semialdehyde dehydrogenase [Zymomonas mobilis]	gene	gene874	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1067
SPy_1068	SPy1068	uvrC	uvrC	876664	878460	+	excinuclease ABC (subunit C)	Best Blastp hit %3D sp|P14951|UVRC_BACSU EXCINUCLEASE ABC SUBUNIT C >gi|98240|pir||A37192 excinuclease ABC%2C chain C - Bacillus subtilis >gi|142521|gb|AAA87316.1| (J03294) deoxyribodipyrimidine photolyase [Bacillus subtilis] >gi|1770045|emb|CAA99578.1| (Z75208) deoxyribodipyrimidine photolyase [Bacillus subtilis] >gi|2635314|emb|CAB14809.1| (Z99118) excinuclease ABC (subunit C) [Bacillus subtilis]	gene	gene875	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1068
SPy_1069	SPy1069		SPy_1069	878645	879247	+	putative NADH dehydrogenase	Best Blastp hit %3D sp|P96707|YDGI_BACSU PUTATIVE NAD(P)H NITROREDUCTASE YDGI >gi|7432645|pir||C69783 NADH dehydrogenase homolog ydgI - Bacillus subtilis >gi|1881372|dbj|BAA19399.1| (AB001488) SIMILAR TO NITROREDUCTASE. [Bacillus subtilis] >gi|2632879|emb|CAB12385.1| (Z99107) similar to NADH dehydrogenase [Bacillus subtilis]	gene	gene876	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1069
SPy_1070	SPy1070		SPy_1070	879372	880781	+	putative dipeptidase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D gb|AAC45369.1| (U78036) dipeptidase [Lactococcus lactis]	gene	gene877	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1070
SPy_1071	SPy1071	thdF	thdF	880849	882225	-	putative thiophene degradation protein F	Best Blastp hit %3D sp|P25811|THDF_BACSU POSSIBLE THIOPHENE AND FURAN OXIDATION PROTEIN THDF >gi|80290|pir||JQ1215 thiophen / furan oxidation protein thdF - Bacillus subtilis >gi|40025|emb|CAA44403.1| (X62539) homologous to E.coli 50K [Bacillus subtilis] >gi|467386|dbj|BAA05232.1| (D26185) thiophen and furan oxidation [Bacillus subtilis] >gi|2636649|emb|CAB16139.1| (Z99124) thdF [Bacillus subtilis]	gene	gene878	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1071
SPy_1072	SPy1072	rplJ	rplJ	882558	883058	+	50S ribosomal protein L10	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB03840.1| (AP001507) ribosomal protein L10 (BL5) [Bacillus halodurans]	gene	gene879	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1072
SPy_1073	SPy1073	rplL	rplL	883123	883488	+	50S ribosomal protein L7/L12	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB03841.1| (AP001507) ribosomal protein L7/L12 [Bacillus halodurans]	gene	gene880	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1073
SPy_1075	SPy1075		SPy_1075	884018	884386	+	hypothetical protein	Best Blastp hit %3D gb|AAD41248.1|AF106927_1 (AF106927) unknown [Streptococcus suis]	gene	gene881	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1075
SPy_1077	SPy1077		SPy_1077	884561	884884	+	putative methyl transferase	Best Blastp hit %3D gb|AAC98421.1| (L29323) methyl transferase [Streptococcus pneumoniae]	gene	gene882	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1077
SPy_1078	SPy1078		SPy_1078	884909	885713	+			gene	gene883	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1078
SPy_1080	SPy1080	srtI	srtI	885722	886369	+	protein involved in lantibiotic (srt) production	Best Blastp hit %3D dbj|BAB08159.1| (AB030831) SrtI [Streptococcus pyogenes]	gene	gene884	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1080
SPy_1081	SPy1081	srtR	srtR	886520	887206	+	putative DNA binding regulatory protein - lantibiotic associated	Best Blastp hit %3D dbj|BAB08160.1| (AB030831) SrtR [Streptococcus pyogenes]	gene	gene885	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1081
SPy_1082	SPy1082	srtK	srtK	887199	888545	+	putative histidine kinase - lantibiotic associated	Best Blastp hit %3D dbj|BAB08161.1| (AB030831) SrtK [Streptococcus pyogenes]	gene	gene886	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1082
SPy_1083	SPy1083	srtA	srtA	888693	888833	+	lantibiotic precursor	Best Blastp hit %3D dbj|BAB08163.1| (AB030831) SrtA [Streptococcus pyogenes]	gene	gene887	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1083
SPy_1084	SPy1084	srtT	srtT	888948	889565	+	ABC transporter (ATP binding) - lantibiotic associated	Best Blastp hit %3D dbj|BAB08163.1| (AB030831) SrtT [Streptococcus pyogenes]	gene	gene888	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1084
SPy_1085	SPy1085	srtF	srtF	889647	890336	+	ABC transporter (ATP-binding) - lantibiotic associated	Best Blastp hit %3D dbj|BAB08166.1| (AB030831) SrtF [Streptococcus pyogenes]	gene	gene889	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1085
SPy_1086	SPy1086	srtE	srtE	890342	891091	+	conserved hypothetical protein - lantibiotic associated	Best Blastp hit %3D dbj|BAB08167.1| (AB030831) SrtE [Streptococcus pyogenes]	gene	gene890	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1086
SPy_1087	SPy1087	srtG	srtG	891094	891816	+	conserved hypothetical protein - lantibiotics associated	Best Blastp hit %3D dbj|BAB08168.1| (AB030831) SrtG [Streptococcus pyogenes]	gene	gene891	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1087
SPy_1088	SPy1088		SPy_1088	892008	892226	+	putative repressor protein - phage associated	Best Blastp hit %3D gb|AAC98432.1| (L29324) repressor protein [Streptococcus pneumoniae]	gene	gene892	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1088
SPy_1092	SPy1092	int2	int2	892717	893799	+		This gene contains multiple sequence confirmed point mutations resulting in the introduction of stop codons throughout the coding region%3B Best Blastp hit %3D dbj|BAB07270.1| (AP001519) integrase (phage-related protein) [Bacillus halodurans]	gene	gene893	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1092
SPy_1093	SPy1093		SPy_1093	894062	895297	+	putative D%2CD-carboxypeptidase%2C penicillin-binding protein	Best Blastp hit %3D emb|CAA67776.1| (X99400) D%2CD-carboxypeptidase [Streptococcus pneumoniae]	gene	gene894	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1093
SPy_1094	SPy1094		SPy_1094	895414	896376	-	hypothetical protein	Best Blastp hit %3D pir||S77609 probable intercellular adhesion protein B precursor - Staphylococcus epidermidis >gi|1161381|gb|AAC06118.1| (U43366) IcaB [Staphylococcus epidermidis]	gene	gene895	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1094
SPy_1096	SPy1096	folC.1	folC.1	896708	897985	+	putative folyl-polyglutamate synthetase	Best Blastp hit %3D sp|Q05865|FOLC_BACSU FOLYLPOLYGLUTAMATE SYNTHASE (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) >gi|421496|pir||B40646 folyl-polyglutamate synthetase folC - Bacillus subtilis >gi|142936|gb|AAB59021.1| (L04520) folyl-polyglutamate synthetase [Bacillus subtilis] >gi|2635273|emb|CAB14768.1| (Z99118) folyl-polyglutamate synthetase [Bacillus subtilis]	gene	gene896	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1096
SPy_1097	SPy1097	folE	folE	897996	898598	+	GTP cyclohydrolase	Best Blastp hit %3D sp|O33723|GCH1_STRPY GTP CYCLOHYDROLASE I (GTP-CH-I) >gi|3242315|emb|CAA04237.1| (AJ000685) GTP cyclohydrolase [Streptococcus pyogenes]	gene	gene897	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1097
SPy_1098	SPy1098	folP	folP	898607	899407	+	dihydropteroate synthase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAA04242.1| (AJ000686) dihydropteroate synthase [Streptococcus pyogenes]	gene	gene898	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1098
SPy_1099	SPy1099	folQ	folQ	899414	899773	+	dihydroneopterin aldolase	Best Blastp hit %3D sp|O33725|FOLB_STRPY DIHYDRONEOPTERIN ALDOLASE (DHNA) >gi|2342544|emb|CAA04239.1| (AJ000685) dihydroneopterin aldolase [Streptococcus pyogenes]	gene	gene899	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1099
SPy_1100	SPy1100	folK	folK	899770	900270	+	hydroxymethylpterin pyrophosphokinase	Best Blastp hit %3D sp|O33726|HPPK_STRPY 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE (7%2C8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (HPPK) (6-HYDROXYMETHYL-7%2C8-DIHYDROPTERIN PYROPHOSPHOKINASE) (PPPK) >gi|3242316|emb|CAA04240.1| (AJ000685) hydroxymethylpterin pyrophosphokinase [Streptococcus pyogenes]	gene	gene900	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1100
SPy_1101	SPy1101	murB	murB	900420	901307	+	putative UDP-N-acetylenolpyruvoylglucosamine reductase	Best Blastp hit %3D dbj|BAB06283.1| (AP001515) UDP-N-acetylenolpyruvoylglucosamine reductase [Bacillus halodurans]	gene	gene901	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1101
SPy_1102	SPy1102	potA	potA	901353	902507	+	putative spermidine / putrescine ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||A70180 spermidine/putrescine ABC transporter%2C ATP-binding protein (potA) homolog - Lyme disease spirochete >gi|2688562|gb|AAB91525.1| (AE001165) spermidine/putrescine ABC transporter%2C ATP-binding protein (potA) [Borrelia burgdorferi]	gene	gene902	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1102
SPy_1103	SPy1103	potB	potB	902491	903285	+	putative spermidine / putrescine ABC transporter (permease protein)	Best Blastp hit %3D sp|P45170|POTB_HAEIN SPERMIDINE/PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTB >gi|1075319|pir||A64118 spermidine/putrescine transport system permease potB - Haemophilus influenzae (strain Rd KW20) >gi|1574805|gb|AAC22990.1| (U32813) spermidine/putrescine ABC transporter%2C permease protein (potB) [Haemophilus influenzae Rd]	gene	gene903	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1103
SPy_1104	SPy1104	potC	potC	903282	904058	+	putative spermidine/putrescine ABC transporter (permease protein)	Best Blastp hit %3D pir||G70179 spermidine/putrescine ABC transporter%2C permease protein (potC) homolog - Lyme disease spirochete >gi|2688564|gb|AAB91527.1| (AE001165) spermidine/putrescine ABC transporter%2C permease protein (potC) [Borrelia burgdorferi]	gene	gene904	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1104
SPy_1105	SPy1105	potD	potD	904051	905124	+	putative spermidine/putrescine ABC transporter (periplasmic transport protein)	Best Blastp hit %3D sp|P23861|POTD_ECOLI SPERMIDINE/PUTRESCINE-BINDING PERIPLASMIC PROTEIN PRECURSOR (SPBP) >gi|96441|pir||D40840 spermidine/putrescine-binding protein precursor [validated] - Escherichia coli >gi|147329|gb|AAC37041.1| (M64519) transport protein [Escherichia coli] >gi|1651550|dbj|BAA35943.1| (D90747) Spermidine/putrescine transport protein D [Escherichia coli] >gi|1787367|gb|AAC74207.1| (AE000212) spermidine/putrescine periplasmic transport protein [Escherichia coli]	gene	gene905	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1105
SPy_1106	SPy1106		SPy_1106	905179	905844	-	putative two-component response regulator	Best Blastp hit %3D dbj|BAB04117.1| (AP001508) two-component response regulator [Bacillus halodurans]	gene	gene906	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1106
SPy_1107	SPy1107		SPy_1107	905825	907366	-	putative two-component sensor histidine kinase	Best Blastp hit %3D dbj|BAB04116.1| (AP001508) two-component sensor histidine kinase [Bacillus halodurans]	gene	gene907	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1107
SPy_1109	SPy1109	malP	malP	907527	908858	+	putative L-malate permease	Best Blastp hit %3D gb|AAB18291.1| (U35658) L-malate permease [Streptococcus bovis]	gene	gene908	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1109
SPy_1110	SPy1110		SPy_1110	908889	910055	+	putative malic enzyme ((S)-malate:NAD+ oxidoreductase (decarboxylating))	Best Blastp hit %3D gb|AAB07709.1| (U35659) malic enzyme [Streptococcus bovis]	gene	gene909	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1110
SPy_1111	SPy1111		SPy_1111	910138	911187	-	putative zinc-containing alcohol dehydrogenase	Best Blastp hit %3D pir||T36961 probable zinc-containing dehydrogenase - Streptomyces coelicolor >gi|5748641|emb|CAB53146.1| (AL109962) putative zinc-containing dehydrogenase [Streptomyces coelicolor A3(2)]	gene	gene910	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1111
SPy_1113	SPy1113		SPy_1113	911423	912154	+	putative acid phosphatase (class B)	Best Blastp hit %3D pir||T09434 acid phosphatase (EC 3.1.3.2) [similarity] - Haemophilus influenzae (strains CCUG%2C Rd KW20) >gi|1514499|emb|CAA68889.1| (Y07615) acid phosphatase [Haemophilus influenzae]	gene	gene911	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1113
SPy_1114	SPy1114		SPy_1114	912332	913864	+	hypothetical protein	Best Blastp hit %3D pir||C82449 conserved hypothetical protein VCA0526 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657932|gb|AAF96429.1| (AE004383) conserved hypothetical protein [Vibrio cholerae]	gene	gene912	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1114
SPy_1115	SPy1115		SPy_1115	914027	914641	+	hypothetical protein	Best Blastp hit %3D sp|P13266|NEUA_ECOLI ACYLNEURAMINATE CYTIDYLYLTRANSFERASE (CMP-N-ACETYLNEURAMINIC ACID SYNTHETASE) (CMP-NEUNAC SYNTHETASE) >gi|95640|pir||A36509 N-acylneuraminate cytidylyltransferase (EC 2.7.7.43) - Escherichia coli >gi|146944|gb|AAA24210.1| (J05023) CMP-N-acetylneuraminic acid synthetase [Escherichia coli]	gene	gene913	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1115
SPy_1117	SPy1117		SPy_1117	914800	915948	+	hypothetical protein	Best Blastp hit %3D gb|AAC05771.1| (AF051356) putative permease [Streptococcus mutans]	gene	gene914	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1117
SPy_1118	SPy1118	radC	radC	915997	916677	+	putative DNA repair protein	Best Blastp hit %3D sp|Q02170|RADC_BACSU DNA REPAIR PROTEIN RADC HOMOLOG (ORFB) >gi|322193|pir||B45239 DNA repair protein homolog ysxA - Bacillus subtilis >gi|142854|gb|AAA22396.1| (M96343) homologous to E. coli radC gene product and to unidentified protein from Staphylococcus aureus [Bacillus subtilis] >gi|143162|gb|AAA22583.1| (L08793) putative [Bacillus subtilis] >gi|2635269|emb|CAB14764.1| (Z99118) similar to DNA repair protein [Bacillus subtilis]	gene	gene915	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1118
SPy_1119	SPy1119		SPy_1119	916679	917374	-	hypothetical protein	Best Blastp hit %3D pir||E70885 hypothetical protein Rv2859c - Mycobacterium tuberculosis (strain H37RV) >gi|2612804|emb|CAA15521.1| (AL008883) hypothetical protein Rv2859c [Mycobacterium tuberculosis]	gene	gene916	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1119
SPy_1120	SPy1120		SPy_1120	917384	918028	-	hypothetical protein	Best Blastp hit %3D dbj|BAA75386.1| (AB013375) YdiH [Bacillus halodurans] >gi|10173164|dbj|BAB04270.1| (AP001508) DNA-binding protein [Bacillus halodurans]	gene	gene917	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1120
SPy_1121	SPy1121		SPy_1121	918280	918627	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene918	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1121
SPy_1122	SPy1122		SPy_1122	918617	919744	-	putative iron-sulfur cofactor synthesis protein	Best Blastp hit %3D pir||E69981 iron-sulfur cofactor synthesis protein yrvO - Bacillus subtilis >gi|2635197|emb|CAB14693.1| (Z99117) similar to NifS protein homolog [Bacillus subtilis] >gi|2635215|emb|CAB14710.1| (Z99118) similar to NifS protein homolog [Bacillus subtilis]	gene	gene919	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1122
SPy_1123	SPy1123	prs	prs	919741	920721	-	putative phosphoribosyl pyrophosphate synthetase	Best Blastp hit %3D sp|P14193|KPRS_BACSU RIBOSE-PHOSPHATE PYROPHOSPHOKINASE (PHOSPHORIBOSYL PYROPHOSPHATE SYNTHETASE) (PRPP SYNTHETASE) >gi|66951|pir||KIBSRS ribose-phosphate pyrophosphokinase (EC 2.7.6.1) prs - Bacillus subtilis >gi|40218|emb|CAA34523.1| (X16518) PRPP synthetase (AA 1-317) [Bacillus subtilis] >gi|467440|dbj|BAA05286.1| (D26185) 'phosphoribosylpyrophosphate synthetase [Bacillus subtilis] >gi|2632318|emb|CAB11827.1| (Z99104) phosphoribosyl pyrophosphate synthetase [Bacillus subtilis]	gene	gene920	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1123
SPy_1124	SPy1124		SPy_1124	920861	921439	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06570.1| (AP001516) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene921	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1124
SPy_1125	SPy1125		SPy_1125	921527	922198	+	putative GTP pyrophosphokinase	Best Blastp hit %3D dbj|BAB06568.1| (AP001516) GTP pyrophosphokinase [Bacillus halodurans]	gene	gene922	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1125
SPy_1126	SPy1126		SPy_1126	922173	923009	+	hypothetical protein	Best Blastp hit %3D sp|O31612|YJBN_BACSU HYPOTHETICAL 30.0 KDA PROTEIN IN MECA-TENA INTERGENIC REGION >gi|7429821|pir||F69844 conserved hypothetical protein yjbN - Bacillus subtilis >gi|2633515|emb|CAB13018.1| (Z99110) similar to hypothetical proteins [Bacillus subtilis]	gene	gene923	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1126
SPy_1127	SPy1127		SPy_1127	923006	923911	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06566.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene924	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1127
SPy_1128	SPy1128	pta	pta	923915	924910	+	putative phosphotransacetylase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB07542.1| (AP001520) phosphotransacetylase [Bacillus halodurans]	gene	gene925	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1128
SPy_1129	SPy1129		SPy_1129	925037	925806	+		There is a sequence confirmed frame shift mutation within this gene%3B Best Blast Hit %3D	gene	gene926	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1129
SPy_1131	SPy1131		SPy_1131	926003	926692	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene927	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1131
SPy_1133	SPy1133		SPy_1133	927112	927840	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAD45529.1|AF162655_1 (AF162655) choline transporter [Streptococcus pneumoniae]	gene	gene928	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1133
SPy_1134	SPy1134		SPy_1134	927827	929359	+	putative ABC transporter (binding protein)	Best Blastp hit %3D gb|AAD45530.1|AF162656_1 (AF162656) choline transporter [Streptococcus pneumoniae]	gene	gene929	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1134
SPy_1135	SPy1135		SPy_1135	929637	930620	+	putative GMP reductase	Best Blastp hit %3D pir||A71887 probable GMP reductase (EC 1.6.6.8) - Helicobacter pylori (strain J99) >gi|4155370|gb|AAD06382.1| (AE001509) GMP REDUCTASE [Helicobacter pylori J99]	gene	gene930	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1135
SPy_1136	SPy1136	xpt	xpt	930925	931506	+	putative xanthine phosphoribosyltransferase	Best Blastp hit %3D emb|CAA13587.1| (AJ233894) xanthine phosphoribosyltransferase [Streptococcus pneumoniae]	gene	gene931	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1136
SPy_1137	SPy1137		SPy_1137	931506	932789	+	putative purine permease	Best Blastp hit %3D sp|O32140|YUNK_BACSU PUTATIVE PURINE PERMEASE YUNK >gi|7446783|pir||F70016 purine permease homolog yunK - Bacillus subtilis >gi|2635741|emb|CAB15234.1| (Z99120) similar to purine permease [Bacillus subtilis]	gene	gene932	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1137
SPy_1138	SPy1138		SPy_1138	932853	933791	-	putative thiamine biosynthesis lipoprotein precursor	Best Blastp hit %3D sp|P33944|APBE_ECOLI THIAMINE BIOSYNTHESIS LIPOPROTEIN APBE PRECURSOR >gi|7449719|pir||D64991 yojL protein - Escherichia coli (strain K-12) >gi|1788543|gb|AAC75274.1| (AE000310) orf%2C hypothetical protein [Escherichia coli]	gene	gene933	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1138
SPy_1139	SPy1139		SPy_1139	933844	934029	-	putative 4-oxalocrotonate tautomerase	Best Blastp hit %3D gb|AAD13221.1| (AF100302) 4-oxalocrotonate tautomerase [Pseudomonas putida]	gene	gene934	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1139
SPy_1140	SPy1140	tdk2	tdk2	934167	934736	+	putative thymidine kinase	Best Blastp hit %3D sp|P47848|KITH_STRGC THYMIDINE KINASE >gi|703442|gb|AAB02289.1| (L40415) thymidine kinase [Streptococcus gordonii]	gene	gene935	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1140
SPy_1141	SPy1141	prfA	prfA	934771	935850	+	putative peptide chain release factor 1	Best Blastp hit %3D sp|P45872|RF1_BACSU PEPTIDE CHAIN RELEASE FACTOR 1 (RF-1) >gi|1075885|pir||S55437 translation releasing factor RF-1 - Bacillus subtilis >gi|853776|emb|CAA89884.1| (Z49782) peptide chain release factor 1 [Bacillus subtilis] >gi|2636226|emb|CAB15718.1| (Z99122) peptide chain release factor 1 [Bacillus subtilis]	gene	gene936	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1141
SPy_1142	SPy1142	hemK	hemK	935850	936689	+	putative protoporphyrinogen oxidase	Best Blastp hit %3D dbj|BAB07493.1| (AP001519) protoporphyrinogen oxidase [Bacillus halodurans]	gene	gene937	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1142
SPy_1143	SPy1143		SPy_1143	936673	937263	+	hypothetical protein	Best Blastp hit %3D pir||D71154 hypothetical protein PH0435 - Pyrococcus horikoshii >gi|3256838|dbj|BAA29521.1| (AP000002) 340aa long hypothetical protein [Pyrococcus horikoshii]	gene	gene938	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1143
SPy_1144	SPy1144		SPy_1144	937281	937733	+	hypothetical protein	Best Blastp hit %3D emb|CAB69747.1| (AL137166) putative acetyltransferase [Streptomyces coelicolor A3(2)]	gene	gene939	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1144
SPy_1145	SPy1145	glyA	glyA	937723	938979	+	putative serine hydroxymethyltransferase	Best Blastp hit %3D sp|P39148|GLYA_BACSU SERINE HYDROXYMETHYLTRANSFERASE (SERINE METHYLASE) (SHMT) >gi|2117693|pir||I40483 glycine hydroxymethyltransferase (EC 2.1.2.1) glyA - Bacillus subtilis >gi|556886|emb|CAA86110.1| (Z38002) serine hydroxymethyltransferase [Bacillus subtilis] >gi|2636215|emb|CAB15707.1| (Z99122) serine hydroxymethyltransferase [Bacillus subtilis] >gi|1095424|prf||2108403J Ser hydroxymethyltransferase [Bacillus subtilis]	gene	gene940	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1145
SPy_1146	SPy1146		SPy_1146	938986	939963	+	hypothetical protein	Best Blastp hit %3D emb|CAB71302.1| (AJ130879) hypothetical protein [Clostridium sticklandii]	gene	gene941	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1146
SPy_1147	SPy1147		SPy_1147	939964	940563	+	hypothetical protein	Best Blastp hit %3D pir||F69900 transposon-related protein homolog yocA - Bacillus subtilis >gi|2619009|gb|AAB84433.1| (AF027868) RAS-related protein [Bacillus subtilis] >gi|2634306|emb|CAB13805.1| (Z99114) similar to transposon-related protein [Bacillus subtilis]	gene	gene942	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1147
SPy_1148	SPy1148		SPy_1148	940573	942297	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D emb|CAB69751.1| (AL137187) putative ABC transporter [Streptomyces coelicolor A3(2)]	gene	gene943	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1148
SPy_1149	SPy1149		SPy_1149	942294	944021	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|Q9WYC4|Y288_THEMA HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN TM0288 >gi|7445855|pir||F72396 ABC transporter%2C ATP-binding protein - Thermotoga maritima (strain MSB8) >gi|4980786|gb|AAD35376.1|AE001710_11 (AE001710) ABC transporter%2C ATP-binding protein [Thermotoga maritima]	gene	gene944	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1149
SPy_1150	SPy1150	nox	nox	944262	945632	+	NADH Oxidase	Best Blastp hit %3D pir||JC4541 NADH oxidase (H2O-forming) (EC 1.6.-.-) - Streptococcus mutans >gi|1199958|dbj|BAA08707.1| (D49951) H2O-forming NADH Oxidase [Streptococcus mutans] >gi|1586930|prf||2205240A H2O-forming NADH oxidase [Streptococcus mutans]	gene	gene945	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1150
SPy_1151	SPy1151	ldh	ldh	945791	946774	-	putative L-lactate dehydrogenase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|Q01462|LDH_LACLA L-LACTATE DEHYDROGENASE >gi|322105|pir||JN0449 L-lactate dehydrogenase (EC 1.1.1.27) - Lactococcus lactis >gi|149424|gb|AAA25187.1| (M88490) L-lactate dehydrogenase [Lactococcus lactis] >gi|435948|gb|AAA61963.1| (U04315) lactate dehydrogenase [Lactococcus lactis] >gi|496964|gb|AAA61962.1| (U02386) lactate dehydrogenase [Lactococcus lactis] >gi|1841733|gb|AAB51676.1| (U78632) L-lactate dehydrogenase [Lactococcus lactis] >gi|1841741|gb|AAB51680.1| (U78636) L-lactate dehydrogenase [Lactococcus lactis] >gi|1841743|gb|AAB51681.1| (U78637) L-lactate dehydrogenase [Lactococcus lactis] >gi|1841745|gb|AAB51682.1| (U78638) L-lactate dehydrogenase [Lactococcus lactis]	gene	gene946	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1151
SPy_1152	SPy1152	gyrA	gyrA	946965	949451	+	DNA gyrase A subunit	Best Blastp hit %3D gb|AAF63266.1| (AF220945) DNA gyrase A subunit [Streptococcus pyogenes]	gene	gene947	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1152
SPy_1154	SPy1154		SPy_1154	949471	950220	+	hypothetical protein	Best Blastp hit %3D gb|AAA73122.1| (M77279) alpha-amylase [unidentified cloning vector]	gene	gene948	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1154
SPy_1155	SPy1155		SPy_1155	950303	950716	+	hypothetical protein	Best Blastp hit %3D sp|P45871|YWKD_BACSU HYPOTHETICAL 14.8 KD PROTEIN IN TDK-PRFA INTERGENIC REGION >gi|1075944|pir||S55436 conserved hypothetical protein ywkD - Bacillus subtilis >gi|853775|emb|CAA89883.1| (Z49782) unknown [Bacillus subtilis] >gi|2636227|emb|CAB15719.1| (Z99122) similar to hypothetical proteins [Bacillus subtilis]	gene	gene949	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1155
SPy_1156	SPy1156		SPy_1156	951203	951322	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene950	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1156
SPy_1157	SPy1157		SPy_1157	951330	951698	+	hypothetical protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||T04147 LEA protein - rice >gi|1486503|gb|AAC03364.1| (U57641) LEA-like protein [Oryza sativa]	gene	gene951	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1157
SPy_1158	SPy1158		SPy_1158	951748	952659	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04395.1| (AP001509) unknown conserved protein [Bacillus halodurans]	gene	gene952	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1158
SPy_1159	SPy1159	hlyIII	hlyIII	952776	953426	-	putative hemolysin III	Best Blastp hit %3D sp|P54175|HLY3_BACSU HEMOLYSIN III HOMOLOG >gi|7449859|pir||D69938 hemolysin III homolog yplQ - Bacillus subtilis >gi|1256643|gb|AAA96637.1| (L77246) 20.2%25 identity with NADH dehydrogenase of the Leishmania major mitochondrion%3B putative [Bacillus subtilis] >gi|2634599|emb|CAB14097.1| (Z99115) similar to hemolysin III homolog [Bacillus subtilis]	gene	gene953	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1159
SPy_1160	SPy1160		SPy_1160	953423	953863	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene954	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1160
SPy_1161	SPy1161		SPy_1161	954082	954930	+	hypothetical protein	Best Blastp hit %3D pir||F69880 conserved hypothetical protein ylqF - Bacillus subtilis >gi|2633977|emb|CAB13478.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene955	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1161
SPy_1162	SPy1162	rnh	rnh	954920	955711	+	putative ribonuclease HII	Best Blastp hit %3D sp|O31744|RNH2_BACSU RIBONUCLEASE HII (RNASE HII) >gi|7435239|pir||C69693 ribonuclease H rnh - Bacillus subtilis >gi|2633978|emb|CAB13479.1| (Z99112) ribonuclease H [Bacillus subtilis]	gene	gene956	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1162
SPy_1163	SPy1163	smf	smf	955776	956612	+	putative DNA processing protein (Smf family)	Best Blastp hit %3D dbj|BAB06187.1| (AP001515) DNA processing protein (Smf family) [Bacillus halodurans]	gene	gene957	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1163
SPy_1164	SPy1164	topA	topA	956719	958848	+	putative DNA topoisomerase I	Best Blastp hit %3D sp|P39814|TOP1_BACSU DNA TOPOISOMERASE I (OMEGA-PROTEIN) (RELAXING ENZYME) (UNTWISTING ENZYME) (SWIVELASE) >gi|7449002|pir||G69724 DNA topoisomerase I topA - Bacillus subtilis >gi|520753|gb|AAA22763.1| (L27797) DNA topoisomerase I [Bacillus subtilis] >gi|2462970|emb|CAA04422.1| (AJ000975) DNA Topoisomerase I [Bacillus subtilis] >gi|2633984|emb|CAB13485.1| (Z99112) DNA topoisomerase I [Bacillus subtilis]	gene	gene958	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1164
SPy_1168	SPy1168		SPy_1168	958923	959805	-		This gene contains multiple sequence confirmed frameshift and point mutations within the coding region%3B Best Blastp hit %3D gb|AAG06982.1|AE004780_1 (AE004780) probable transcriptional regulator [Pseudomonas aeruginosa]	gene	gene959	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1168
SPy_1169	SPy1169		SPy_1169	959818	960363	+	hypothetical protein	Best Blastp hit %3D pir||E71373 probable regulatory protein (pfoS/R) - syphilis spirochete >gi|3322295|gb|AAC65034.1| (AE001189) regulatory protein (pfoS/R) [Treponema pallidum]	gene	gene960	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1169
SPy_1170	SPy1170	ddh	ddh	960378	961370	+	putative D-specific D-2-hydroxyacid dehydrogenase	Best Blastp hit %3D gb|AAB17663.1| (U31175) D-specific D-2-hydroxyacid dehydrogenase [Staphylococcus aureus]	gene	gene961	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1170
SPy_1171	SPy1171	satD	satD	961475	962140	+	hypothetical protein	Best Blastp hit %3D gb|AAG28336.1| (U88582) SatD [Streptococcus mutans]	gene	gene962	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1171
SPy_1172	SPy1172	satE	satE	962133	962849	+	hypothetical protein	Best Blastp hit %3D gb|AAG28337.1| (U88582) SatE [Streptococcus mutans]	gene	gene963	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1172
SPy_1173	SPy1173	gid	gid	963000	964346	+	putative glucose-inhibited division protein	Best Blastp hit %3D sp|P39815|GID_BACSU GID PROTEIN >gi|7474859|pir||A69632 glucose-inhibited division protein gid - Bacillus subtilis >gi|2462971|emb|CAA04423.1| (AJ000975) Gid protein [Bacillus subtilis] >gi|2633985|emb|CAB13486.1| (Z99112) glucose-inhibited division protein [Bacillus subtilis]	gene	gene964	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1173
SPy_1174	SPy1174		SPy_1174	964499	965905	+	putative transcarboxylase subunit	Best Blastp hit %3D sp|Q58628|PYCB_METJA PYRUVATE CARBOXYLASE SUBUNIT B (PYRUVIC CARBOXYLASE B) >gi|2129173|pir||F64453 oxaloacetate decarboxylase (EC 4.1.1.3) alpha chain MJ1231 [similarity] - Methanococcus jannaschii >gi|1591862|gb|AAB99233.1| (U67563) oxaloacetate decarboxylase alpha chain (oadA) [Methanococcus jannaschii]	gene	gene965	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1174
SPy_1175	SPy1175		SPy_1175	965948	966262	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene966	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1175
SPy_1176	SPy1176		SPy_1176	966262	966612	+	putative methylmalonyl-CoA decarboxylase%2C gamma-subunit	Best Blastp hit %3D pir||D49094 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) gamma chain - Veillonella parvula >gi|415596|gb|AAC36823.1| (L22208) methylmalonyl-CoA decarboxylase gamma-subunit [Veillonella parvula] >gi|415918|emb|CAA80875.1| (Z24754) gamma-subunit%2Cmethylmalonyl-CoA decarboxylase [Veillonella parvula]	gene	gene967	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1176
SPy_1177	SPy1177		SPy_1177	966622	967752	+	putative methylmalonyl-CoA decarboxylase%2C beta-subunit	Best Blastp hit %3D pir||T44985 methylmalonyl-CoA decarboxylase (EC 4.1.1.41) beta chain [validated] - Propionigenium modestum >gi|2706401|emb|CAA05140.1| (AJ002015) methylmalonyl-CoA decarboxylase%2C beta-subunit [Propionigenium modestum]	gene	gene968	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1177
SPy_1178	SPy1178	citG	citG	967952	968836	-	CitG-like protein	Best Blastp hit %3D sp|O30827|CITG_HAEDU CITG PROTEIN >gi|2407236|gb|AAC46220.1| (AF017750) CitG protein homolog [Haemophilus ducreyi]	gene	gene969	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1178
SPy_1179	SPy1179		SPy_1179	968829	969524	-	putative transcriptional regulator	Best Blastp hit %3D emb|CAC12514.1| (AL445067) Nta operon transcriptional regulator related protein [Thermoplasma acidophilum]	gene	gene970	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1179
SPy_1180	SPy1180		SPy_1180	969682	971088	-	putative Mg2+/citrate complex transporter	Best Blastp hit %3D sp|P42308|CITN_BACSU CITRATE TRANSPORTER >gi|7475623|pir||D70078 Mg2+/citrate complex transporter homolog yxiQ - Bacillus subtilis >gi|665994|dbj|BAA11698.1| (D83026) hypothetical [Bacillus subtilis] >gi|2636441|emb|CAB15932.1| (Z99123) similar to Mg2+/citrate complex transporter [Bacillus subtilis] >gi|2636452|emb|CAB15942.1| (Z99124) similar to Mg2+/citrate complex transporter [Bacillus subtilis]	gene	gene971	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1180
SPy_1181	SPy1181		SPy_1181	971465	971788	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene972	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1181
SPy_1183	SPy1183		SPy_1183	971842	972240	+	putative decarboxylase%2C gamma chain	Best Blastp hit %3D sp|P29337|BCCP_STRMU BIOTIN CARBOXYL CARRIER PROTEIN (BCCP) >gi|153584|gb|AAA03702.1| (M80523) biotin carboxyl carrier protein [Streptococcus mutans]	gene	gene973	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1183
SPy_1184	SPy1184		SPy_1184	972285	973406	+	putative decarboxylase%2C beta subunit	Best Blastp hit %3D pir||C69510 oxaloacetate decarboxylase%2C sodium ion pump subunit (oadB) homolog - Archaeoglobus fulgidus >gi|2648455|gb|AAB89172.1| (AE000960) oxaloacetate decarboxylase%2C sodium ion pump subunit (oadB) [Archaeoglobus fulgidus]	gene	gene974	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1184
SPy_1186	SPy1186	citD	citD	973594	973902	+	putative citrate lyase%2C gamma subunit	Best Blastp hit %3D gb|AAF93961.1| (AE004165) citrate lyase%2C gamma subunit [Vibrio cholerae]	gene	gene975	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1186
SPy_1188	SPy1188	citE	citE	973890	974777	+	putative citrate lyase%2C beta subunit	Best Blastp hit %3D sp|O53078|CILB_LEUMC CITRATE LYASE BETA CHAIN (CITRASE) (CITRYL-COA LYASE SUBUNIT) >gi|2842396|emb|CAA71632.1| (Y10621) CILB%2C citryl-CoA lyase beta subunit [Leuconostoc mesenteroides]	gene	gene976	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1188
SPy_1189	SPy1189	citF	citF	974780	976312	+	putative citrate lyase%2C alpha subunit	Best Blastp hit %3D sp|O53079|CILA_LEUMC CITRATE LYASE ALPHA CHAIN (CITRASE) (CITRATE COA-TRANSFERASE SUBUNIT) >gi|2842397|emb|CAA71633.1| (Y10621) CILA%2C citrate CoA-transferase alpha subunit [Leuconostoc mesenteroides]	gene	gene977	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1189
SPy_1190	SPy1190	citX	citX	976305	976883	+	hypothetical protein	Best Blastp hit %3D sp|O53080|CITG_LEUMC CITG PROTEIN >gi|2842398|emb|CAA71634.1| (Y10621) CILG%2C hypothetical protein [Leuconostoc mesenteroides]	gene	gene978	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1190
SPy_1191	SPy1191	oadA	oadA	976883	978292	+	putative oxaloacetate decarboxylase alpha chain	Best Blastp hit %3D sp|Q58628|PYCB_METJA PYRUVATE CARBOXYLASE SUBUNIT B (PYRUVIC CARBOXYLASE B) >gi|2129173|pir||F64453 oxaloacetate decarboxylase (EC 4.1.1.3) alpha chain MJ1231 [similarity] - Methanococcus jannaschii >gi|1591862|gb|AAB99233.1| (U67563) oxaloacetate decarboxylase alpha chain (oadA) [Methanococcus jannaschii]	gene	gene979	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1191
SPy_1192	SPy1192	citC	citC	978402	979454	-	putative citrate lyase synthetase (citrate (pro-3S)-lyase ligase)	Best Blastp hit %3D pir||H64795 citrate (pro-3S)-lyase ligase (EC 6.2.1.22) - Escherichia coli >gi|1778535|gb|AAB40818.1| (U82598) HI0025 homolog [Escherichia coli] >gi|1786835|gb|AAC73719.1| (AE000166) citrate lyase synthetase (citrate (pro-3S)-lyase ligase [Escherichia coli]	gene	gene980	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1192
SPy_1193	SPy1193		SPy_1193	979543	980025	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene981	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1193
SPy_1196	SPy1196		SPy_1196	980725	981795	-	putative integrase/recombinase	Best Blastp hit %3D emb|CAA55635.1| (X78999) unknown [Lactobacillus leichmannii]	gene	gene982	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1196
SPy_1198	SPy1198		SPy_1198	982264	982962	+	putative repressor protein	Best Blastp hit %3D pir||C28551 hypothetical protein 3 - Streptococcus mutans (strain GS-5) (fragment) >gi|1196926|gb|AAA88585.1| (M18954) unknown protein [Streptococcus mutans]	gene	gene983	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1198
SPy_1200	SPy1200	ffh	ffh	983079	984641	-	putative signal recognition particle	Best Blastp hit %3D dbj|BAB06203.1| (AP001515) signal recognition particle [Bacillus halodurans]	gene	gene984	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1200
SPy_1201	SPy1201	ylxM	ylxM	984656	984997	-	putative DNA-binding protein	Best Blastp hit %3D gb|AAC44501.1| (U48884) uncharacterized open reading frame%3B hypothetical protein displaying similarity to a Bacillus subtilis hypothetical protein (Ylm [Streptococcus mutans]	gene	gene985	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1201
SPy_1202	SPy1202		SPy_1202	985086	985811	-	putative transcription regulator%2C GntR family	Best Blastp hit %3D pir||E75573 transcription regulator%2C GntR family - Deinococcus radiodurans (strain R1) >gi|6460714|gb|AAF12419.1|AE001863_44 (AE001863) transcriptional regulator%2C GntR family [Deinococcus radiodurans]	gene	gene986	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1202
SPy_1203	SPy1203		SPy_1203	985867	987300	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene987	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1203
SPy_1204	SPy1204	guaA	guaA	987467	989029	+	putative GMP synthase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D gb|AAD15805.1| (AF058326) GMP synthase [Lactococcus lactis]	gene	gene988	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1204
SPy_1205	SPy1205		SPy_1205	989071	990294	-	putative antimicrobial resistance factor	Best Blastp hit %3D emb|CAB89535.1| (AJ250764) MurM protein [Streptococcus pneumoniae]	gene	gene989	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1205
SPy_1206	SPy1206		SPy_1206	990659	992224	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|O05519|YDIF_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YDIF >gi|7445765|pir||G69786 ABC transporter (ATP-binding protein) homolog ydiF - Bacillus subtilis >gi|1945111|dbj|BAA19719.1| (D88802) H. influenzae hypothetical ABC transporter%3B P44808 (974) [Bacillus subtilis] >gi|2632908|emb|CAB12414.1| (Z99107) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene990	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1206
SPy_1208	SPy1208		SPy_1208	992337	992894	-	hypothetical protein	Best Blastp hit %3D pir||F70342 cation efflux system (AcrB/AcrD/AcrF family) - Aquifex aeolicus >gi|2983120|gb|AAC06724.1| (AE000691) cation efflux system (AcrB/AcrD/AcrF family) [Aquifex aeolicus]	gene	gene991	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1208
SPy_1209	SPy1209	pdxK	pdxK	992872	993738	-	putative pyridoxal kinase	Best Blastp hit %3D pir||G70195 pyridoxal kinase (pdxK) homolog - Lyme disease spirochete >gi|2688703|gb|AAC67112.1| (AE001176) pyridoxal kinase (pdxK) [Borrelia burgdorferi]	gene	gene992	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1209
SPy_1210	SPy1210		SPy_1210	993828	995096	+	hypothetical protein	Best Blastp hit %3D gb|AAD24445.1|AF118389_2 (AF118389) unknown [Streptococcus suis]	gene	gene993	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1210
SPy_1211	SPy1211		SPy_1211	995494	995850	-	hypothetical protein	This ORF is similar to the amino terminus of anaerobic ribonucleoside-triphosphate reductase%3B Best Blastp hit %3D sp|P43752|NRDD_HAEIN ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE >gi|1073847|pir||A64047 ribonucleoside-triphosphate reductase%2C oxygen-sensitive (EC 1.17.4.-) - Haemophilus influenzae (strain Rd KW20) >gi|1573024|gb|AAC21751.1| (U32693) anaerobic ribonucleoside-triphosphate reductase (nrdD) [Haemophilus influenzae Rd]	gene	gene994	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1211
SPy_1212	SPy1212		SPy_1212	996172	997749	-	putative cardiolipin synthetase	Best Blastp hit %3D dbj|BAB06577.1| (AP001516) cardiolipin synthetase [Bacillus halodurans]	gene	gene995	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1212
SPy_1213	SPy1213	fhs.1	fhs.1	997834	999504	-	putative formate-tetrahydrofolate ligase	Best Blastp hit %3D sp|P13419|FTHS_CLOAC FORMATE-TETRAHYDROFOLATE LIGASE (FORMYLTETRAHYDROFOLATE SYNTHETASE) (FHS) (FTHFS) >gi|98563|pir||A28185 formate-tetrahydrofolate ligase (EC 6.3.4.3) - Clostridium acidiurici >gi|144810|gb|AAA53187.1| (M21507) 10-formyltetrahydrofolate synthetase (EC 6.3.4.3) [Clostridium acidi-urici]	gene	gene996	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1213
SPy_1214	SPy1214	lplA	lplA	999632	1000651	-	putative lipoate-protein ligase	Best Blastp hit %3D dbj|BAB04402.1| (AP001509) lipoate-protein ligase [Bacillus halodurans]	gene	gene997	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1214
SPy_1215	SPy1215		SPy_1215	1000698	1001579	-	hypothetical protein	Best Blastp hit %3D emb|CAA20062.2| (AL031154) hypothetical protein [Schizosaccharomyces pombe]	gene	gene998	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1215
SPy_1216	SPy1216		SPy_1216	1001572	1002384	-	hypothetical protein	Best Blastp hit %3D pir||I39569 protein 2 - Alcaligenes eutrophus >gi|695280|gb|AAC41426.1| (L36817) ORF2 [Ralstonia eutropha] >gi|1093467|prf||2104199H ORF 2 [Ralstonia eutropha]	gene	gene999	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1216
SPy_1217	SPy1217		SPy_1217	1002377	1002709	-	putative glycine cleavage system H protein	Best Blastp hit %3D gb|AAF81345.1|AC007767_25 (AC007767) Identical to a glycine cleavage system H-protein precursor from Arabidopsis thaliana gb|P25855. It contains a glycine cleavage H-protein domain PF|01597. ESTs gb|R90208%2C gb|AI994794%2C gb|AA605324%2C gb|N38240%2C gb|AV533336%2C gb|AV534187%2C gb|AA5>	gene	gene1000	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1217
SPy_1218	SPy1218		SPy_1218	1002751	1003749	-	hypothetical protein	Best Blastp hit %3D sp|P39606|YWCH_BACSU HYPOTHETICAL 36.6 KDA PROTEIN IN QOXD-VPR INTERGENIC REGION >gi|629051|pir||S39699 monooxygenase homolog ywcH - Bacillus subtilis >gi|413968|emb|CAA51600.1| (X73124) ipa-44d [Bacillus subtilis] >gi|2636345|emb|CAB15836.1| (Z99123) alternate gene name: ipa-44d~similar to monooxygenase [Bacillus subtilis]	gene	gene1001	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1218
SPy_1219	SPy1219		SPy_1219	1003746	1004945	-	putative trimethylamine dehydrogenase	Best Blastp hit %3D sp|P54524|YQIG_BACSU PROBABLE NADH-DEPENDENT FLAVIN OXIDOREDUCTASE YQIG >gi|7449899|pir||C69961 NADH-dependent flavin oxidoreductase homolog yqiG - Bacillus subtilis >gi|1303926|dbj|BAA12582.1| (D84432) YqiG [Bacillus subtilis] >gi|2634855|emb|CAB14352.1| (Z99116) similar to NADH-dependent flavin oxidoreductase [Bacillus subtilis]	gene	gene1002	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1219
SPy_1220	SPy1220		SPy_1220	1004942	1005793	-	hypothetical protein	Best Blastp hit %3D sp|P39648|YWFL_BACSU HYPOTHETICAL 31.4 KD PROTEIN IN PTA 3'REGION >gi|629097|pir||S39745 ywfL protein - Bacillus subtilis >gi|414014|emb|CAA51646.1| (X73124) ipa-90d [Bacillus subtilis] >gi|2636300|emb|CAB15791.1| (Z99123) alternate gene name: ipa-90d [Bacillus subtilis]	gene	gene1003	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1220
SPy_1221	SPy1221	dpfB	dpfB	1005980	1006666	+	putative flavoprotein	This orf is equivalent in length to flavoprotein predicted in Lactococcus lactis subsp. lactis although it appears considerably shorter than the pantothenate metabolism flavoprotein dfp homologs from other sources%3B Best Blast Hit %3D gi|12723463|gb|AAK04671.1|AE006291_5 (AE006291) flavoprotein [Lactococcus lactis subsp. lactis]	gene	gene1004	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1221
SPy_1222	SPy1222	dfp	dfp	1006659	1007204	+	putative DNA/pantothenate metabolism flavoprotein	Best Blastp hit %3D sp|Q54433|DFP_STRMU DNA/PANTOTHENATE METABOLISM FLAVOPROTEIN HOMOLOG >gi|1216490|gb|AAC44502.1| (U48885) DNA/pantothenate metabolism flavoprotein [Streptococcus mutans]	gene	gene1005	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1222
SPy_1223	SPy1223		SPy_1223	1007262	1007831	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1006	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1223
SPy_1224	SPy1224	pgmA	pgmA	1008007	1009725	+	putative phosphoglucomutase	Best Blastp hit %3D emb|CAB96418.1| (AJ243290) phosphoglucomutase [Streptococcus thermophilus]	gene	gene1007	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1224
SPy_1225	SPy1225		SPy_1225	1009938	1010894	-	putative sugar ABC transporter (permease protein)	Best Blastp hit %3D pir||A72419 sugar ABC transporter%2C permease protein - Thermotoga maritima (strain MSB8) >gi|4980595|gb|AAD35199.1|AE001696_13 (AE001696) sugar ABC transporter%2C permease protein [Thermotoga maritima]	gene	gene1008	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1225
SPy_1226	SPy1226		SPy_1226	1010896	1011960	-	putative sugar ABC transporter (permease protein)	Best Blastp hit %3D emb|CAC14306.1| (AJ276209) putative permease 1 of an ABC transporter [Clostridium sticklandii]	gene	gene1009	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1226
SPy_1227	SPy1227		SPy_1227	1011953	1013485	-	putative sugar ABC transporter (ATP-binding protein)	Best Blastp hit %3D emb|CAC14305.1| (AJ276209) putative ATP-binding protein of an ABC-transporter [Clostridium sticklandii]	gene	gene1010	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1227
SPy_1228	SPy1228		SPy_1228	1013624	1014676	-	putative lipoprotein	Best Blastp hit %3D sp|Q48754|TCSA_LISMO CD4+ T CELL-STIMULATING ANTIGEN PRECURSOR >gi|7240601|gb|AAB35725.2| (S80336) CD4+ T cell-stimulating antigen [Listeria monocytogenes]	gene	gene1011	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1228
SPy_1230	SPy1230	cdd	cdd	1014770	1015159	-	putative cytidine deaminase	Best Blastp hit %3D emb|CAB51906.1| (AJ237978) cytidine deaminase [Bacillus psychrophilus]	gene	gene1012	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1230
SPy_1232	SPy1232		SPy_1232	1015812	1016405	-	hypothetical protein	Best Blastp hit %3D sp|P37872|YBXB_BACSU HYPOTHETICAL 22.5 KDA PROTEIN IN RPLL-RPOB INTERGENIC REGION (P23) (ORF23) >gi|7449576|pir||F69751 conserved hypothetical protein ybxB - Bacillus subtilis >gi|402362|gb|AAB00971.1| (L24376) hypothetical protein [Bacillus subtilis] >gi|2632373|emb|CAB11882.1| (Z99104) alternate gene name: ybaA~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1013	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1232
SPy_1233	SPy1233	coaA	coaA	1016673	1017593	+	putative pantothenate kinase	Best Blastp hit %3D dbj|BAB06594.1| (AP001516) pantothenate kinase [Bacillus halodurans]	gene	gene1014	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1233
SPy_1234	SPy1234	rpsT	rpsT	1017662	1017895	+	30S ribosomal protein S20	Best Blastp hit %3D dbj|BAB05058.1| (AP001511) ribosomal protein S20 (BS20) [Bacillus halodurans]	gene	gene1015	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1234
SPy_1236	SPy1236		SPy_1236	1018020	1019330	-	putative histidine kinase protein	Best Blastp hit %3D gb|AAF79919.1| (AF039082) putative histidine protein kinase [Lactococcus lactis]	gene	gene1016	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1236
SPy_1237	SPy1237		SPy_1237	1019323	1019997	-	putative response regulator	Best Blastp hit %3D emb|CAB54564.1| (AJ005926) response regulator [Streptococcus pneumoniae]	gene	gene1017	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1237
SPy_1239	SPy1239	pepN	pepN	1020343	1022880	-	putative lysyl-aminopeptidase%3B aminopeptidase N	Best Blastp hit %3D sp|Q48656|AMPN_LACLA AMINOPEPTIDASE N (LYSYL AMINOPEPTIDASE) (LYS-AP) (ALANINE AMINOPEPTIDASE) >gi|628947|pir||JU0191 lysyl aminopeptidase (EC 3.4.11.15) precursor - Lactococcus lactis >gi|1256919|dbj|BAA07234.1| (D38040) lysyl-aminopeptidase [Lactococcus lactis]	gene	gene1018	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1239
SPy_1240	SPy1240	phoU	phoU	1023085	1023738	-	putative phosphate uptake regulatory protein	Best Blastp hit %3D sp|Q51547|PHOU_PSEAE PHOSPHATE TRANSPORT SYSTEM PROTEIN PHOU >gi|2120627|pir||S65576 negative regulator PhoU - Pseudomonas aeruginosa >gi|2120628|pir||S68596 negative regulator PhoU - Pseudomonas aeruginosa >gi|633996|dbj|BAA08138.1| (D45195) a negative regulator of pho regulon [Pseudomonas aeruginosa] >gi|9951686|gb|AAG08750.1|AE004948_6 (AE004948) phosphate uptake regulatory protein PhoU [Pseudomonas aeruginosa]	gene	gene1019	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1240
SPy_1241	SPy1241	pstB	pstB	1023806	1024567	-	phosphate ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P46341|YQGJ_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YQGJ >gi|7442551|pir||D69956 phosphate ABC transporter (ATP-binding pro) homolog yqgJ - Bacillus subtilis >gi|903306|dbj|BAA09584.1| (D58414) ORF74 [Bacillus subtilis] >gi|1303857|dbj|BAA12513.1| (D84432) YqgJ [Bacillus subtilis] >gi|2634929|emb|CAB14426.1| (Z99116) alternate gene name: yzmE~similar to phosphate ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene1020	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1241
SPy_1242	SPy1242	pstB2	pstB2	1024577	1025380	-	putative phosphate ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P46341|YQGJ_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YQGJ >gi|7442551|pir||D69956 phosphate ABC transporter (ATP-binding pro) homolog yqgJ - Bacillus subtilis >gi|903306|dbj|BAA09584.1| (D58414) ORF74 [Bacillus subtilis] >gi|1303857|dbj|BAA12513.1| (D84432) YqgJ [Bacillus subtilis] >gi|2634929|emb|CAB14426.1| (Z99116) alternate gene name: yzmE~similar to phosphate ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene1021	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1242
SPy_1243	SPy1243	pstC	pstC	1025396	1026283	-	putative phosphate ABC transporter (permease protein)	Best Blastp hit %3D pir||D69098 phosphate transporter permease PstC homolog - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622861|gb|AAB86200.1| (AE000929) phosphate transporter permease PstC homolog [Methanobacterium thermoautotrophicum]	gene	gene1022	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1243
SPy_1244	SPy1244	pstC2	pstC2	1026273	1027208	-	putative phosphate ABC transporter (permease protein)	Best Blastp hit %3D pir||B69098 phosphate transporter permease PstC - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622860|gb|AAB86199.1| (AE000929) phosphate transporter permease PstC [Methanobacterium thermoautotrophicum]	gene	gene1023	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1244
SPy_1245	SPy1245	pstS	pstS	1027219	1028085	-	putative phosphate ABC transporter%2C periplasmic phosphate-binding protein	Best Blastp hit %3D pir||B82504 phosphate ABC transporter%2C periplasmic phosphate-binding protein VCA0070 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9657454|gb|AAF95984.1| (AE004350) phosphate ABC transporter%2C periplasmic phosphate-binding protein [Vibrio cholerae]	gene	gene1024	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1245
SPy_1246	SPy1246		SPy_1246	1028224	1029534	-	putative nucleolar protein	Best Blastp hit %3D pir||C64945 probable rRNA methylase yebU - Escherichia coli >gi|1736482|dbj|BAA15648.1| (D90827) Proliferating-cell nucleolar antigen P120 (Proliferation-associated nucleolar protein P120). [Escherichia coli] >gi|1788140|gb|AAC74905.1| (AE000278) putative nucleolar proteins [Escherichia coli]	gene	gene1025	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1246
SPy_1247	SPy1247		SPy_1247	1029537	1030325	-	putative myo-inositol-1(or 4)-monophosphatase	Best Blastp hit %3D dbj|BAB06354.1| (AP001516) myo-inositol-1(or 4)-monophosphatase [Bacillus halodurans]	gene	gene1026	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1247
SPy_1248	SPy1248		SPy_1248	1030315	1030593	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06357.1| (AP001516) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1027	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1248
SPy_1249	SPy1249		SPy_1249	1030595	1030999	-	hypothetical protein	Best Blastp hit %3D sp|O31602|YJBD_BACSU HYPOTHETICAL 15.5 KDA PROTEIN IN OPPF-MECA INTERGENIC REGION >gi|7429507|pir||D69843 conserved hypothetical protein yjbD - Bacillus subtilis >gi|2633504|emb|CAB13007.1| (Z99110) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1028	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1249
SPy_1250	SPy1250	mreA	mreA	1031042	1031974	-	putative macrolide-efflux protein	Best Blastp hit %3D gb|AAF77614.1|AF151719_1 (AF151719) RibC-like protein [Streptococcus thermophilus]	gene	gene1029	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1250
SPy_1251	SPy1251	truB	truB	1032003	1032887	-	putative tRNA pseudouridine 55 synthase	Best Blastp hit %3D sp|P32732|TRUB_BACSU TRNA PSEUDOURIDINE SYNTHASE B (TRNA PSEUDOURIDINE 55 SYNTHASE) (PSI55 SYNTHASE) (PSEUDOURIDYLATE SYNTHASE) (URACIL HYDROLYASE) >gi|7444626|pir||G69726 tRNA-pseudouridine synthase (EC 5.4.99.-) - Bacillus subtilis >gi|2634038|emb|CAB13539.1| (Z99112) tRNA pseudouridine 55 synthase [Bacillus subtilis]	gene	gene1030	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1251
SPy_1252	SPy1252		SPy_1252	1033003	1034343	-	hypothetical protein	Best Blastp hit %3D sp|P47394|Y148_MYCGE HYPOTHETICAL PROTEIN MG148 >gi|1361569|pir||D64216 hypothetical protein homolog MG148 - Mycoplasma genitalium >gi|3844741|gb|AAC71366.1| (U39695) conserved hypothetical protein [Mycoplasma genitalium]	gene	gene1031	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1252
SPy_1253	SPy1253		SPy_1253	1034440	1035396	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05183.1| (AP001512) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1032	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1253
SPy_1254	SPy1254		SPy_1254	1035407	1036003	-	hypothetical protein	Best Blastp hit %3D emb|CAA10700.1| (AJ132566) HsdS protein [Escherichia coli]	gene	gene1033	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1254
SPy_1255	SPy1255		SPy_1255	1036095	1038731	-	hypothetical protein	Best Blastp hit %3D pir||E69433 conserved hypothetical protein AF1470 - Archaeoglobus fulgidus >gi|2649098|gb|AAB89778.1| (AE001001) conserved hypothetical protein [Archaeoglobus fulgidus]	gene	gene1034	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1255
SPy_1257	SPy1257		SPy_1257	1038746	1039447	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||H72342 ABC transporter%2C ATP-binding protein - Thermotoga maritima (strain MSB8) >gi|4981229|gb|AAD35787.1|AE001742_2 (AE001742) ABC transporter%2C ATP-binding protein [Thermotoga maritima]	gene	gene1035	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1257
SPy_1258	SPy1258		SPy_1258	1039565	1040107	+	putative transcriptional regulator (TetR/AcrR family)	Best Blastp hit %3D dbj|BAB04438.1| (AP001509) transcriptional regulator (TetR/AcrR family) [Bacillus halodurans]	gene	gene1036	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1258
SPy_1259	SPy1259		SPy_1259	1040250	1040891	-	putative transcriptional regulator	Best Blastp hit %3D dbj|BAA83965.1| (AB024564) YHCF [Bacillus halodurans] >gi|10172996|dbj|BAB04102.1| (AP001508) transcriptional regulator (GntR family) [Bacillus halodurans]	gene	gene1037	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1259
SPy_1260	SPy1260		SPy_1260	1041054	1041545	-	hypothetical protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAA03877.1| (AJ000042) gls24 [Enterococcus faecalis]	gene	gene1038	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1260
SPy_1261	SPy1261		SPy_1261	1041553	1041753	-	hypothetical protein	Best Blastp hit %3D emb|CAB85690.1| (AJ271696) mismatched base pair and cruciform DNA recognition protein [Agaricus bisporus]	gene	gene1039	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1261
SPy_1262	SPy1262		SPy_1262	1041794	1042333	-	hypothetical protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAA03877.1| (AJ000042) gls24 [Enterococcus faecalis]	gene	gene1040	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1262
SPy_1263	SPy1263		SPy_1263	1042346	1042534	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1041	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1263
SPy_1264	SPy1264		SPy_1264	1042545	1043156	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1042	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1264
SPy_1265	SPy1265		SPy_1265	1043193	1043441	-	hypothetical protein	Best Blastp hit %3D pir||F70070 conserved hypothetical protein ywzA - Bacillus subtilis >gi|2636353|emb|CAB15844.1| (Z99123) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1043	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1265
SPy_1267	SPy1267	pcrA	pcrA	1043805	1046123	-	putative ATP-dependent DNA helicase	Best Blastp hit %3D sp|O34580|PCRA_BACSU ATP-DEPENDENT DNA HELICASE PCRA >gi|7436413|pir||E69794 ATP-dependent DNA helicase homolog yerF - Bacillus subtilis >gi|2577965|emb|CAA75552.1| (Y15254) PcrA protein [Bacillus subtilis] >gi|2632975|emb|CAB12481.1| (Z99107) similar to ATP-dependent DNA helicase [Bacillus subtilis]	gene	gene1044	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1267
SPy_1270	SPy1270		SPy_1270	1046652	1047974	+	putative amino acid symporter	Best Blastp hit %3D pir||H82200 sodium/alanine symporter VC1422 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9655920|gb|AAF94579.1| (AE004221) sodium/alanine symporter [Vibrio cholerae]	gene	gene1045	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1270
SPy_1272	SPy1272		SPy_1272	1048094	1049329	+	putative cation efflux system protein	Best Blastp hit %3D sp|P46348|YEAB_BACSU HYPOTHETICAL 31.8 KD PROTEIN IN GABP-GUAA INTERGENIC REGION (ORFX) >gi|7447652|pir||B69791 cation efflux system membrane protein homolog yeaB - Bacillus subtilis >gi|1708640|gb|AAB62307.1| (U51115) YeaB [Bacillus subtilis] >gi|2632945|emb|CAB12451.1| (Z99107) alternate gene name: ydxT~similar to cation efflux system membrane protein [Bacillus subtilis]	gene	gene1046	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1272
SPy_1273	SPy1273	cfa	cfa	1049698	1050471	-	CAMP factor	Best Blastp hit %3D emb|CAA51283.1| (X72754) cAMP factor [Streptococcus agalactiae]	gene	gene1047	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1273
SPy_1274	SPy1274		SPy_1274	1050841	1051677	-	putative amino acid ABC transporter%2C periplasmic amino acid-binding protein	Best Blastp hit %3D gb|AAD56629.1|AF165218_4 (AF165218) AatB [Streptococcus pneumoniae]	gene	gene1048	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1274
SPy_1275	SPy1275		SPy_1275	1051693	1052322	-	putative amino acid ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P10346|GLNQ_ECOLI GLUTAMINE TRANSPORT ATP-BINDING PROTEIN GLNQ >gi|72464|pir||QRECGQ glutamine transport protein glnQ - Escherichia coli >gi|581098|emb|CAA32384.1| (X14180) GlnQ (AA 1-240)%3B gtg start [Escherichia coli] >gi|1651363|dbj|BAA35481.1| (D90718) Glutamine transport protein GlnQ. [Escherichia coli] >gi|1651369|dbj|BAA35491.1| (D90719) Glutamine transport protein GlnQ. [Escherichia coli] >gi|1787029|gb|AAC73896.1| (AE000183) ATP-binding component of glutamine high-affinity transport system [Escherichia coli]	gene	gene1049	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1275
SPy_1276	SPy1276		SPy_1276	1052332	1052973	-	putative amino acid ABC transporter (permease protein)	Best Blastp hit %3D pir||A72357 amino acid ABC transporter%2C permease protein - Thermotoga maritima (strain MSB8) >gi|4981111|gb|AAD35677.1|AE001734_4 (AE001734) amino acid ABC transporter%2C permease protein [Thermotoga maritima]	gene	gene1050	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1276
SPy_1277	SPy1277		SPy_1277	1053079	1053414	-	hypothetical protein	Best Blastp hit %3D gb|AAG03518.1|AE004450_13 (AE004450) conserved hypothetical protein [Pseudomonas aeruginosa]	gene	gene1051	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1277
SPy_1280	SPy1280	glmS	glmS	1053610	1055424	-	putative L-glutamine-D-fructose-6-phosphate amidotransferase	Best Blastp hit %3D dbj|BAB03987.1| (AP001507) L-glutamine-D-fructose-6-phosphate amidotransferase [Bacillus halodurans]	gene	gene1052	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1280
SPy_1281	SPy1281	sipC	sipC	1055600	1056157	-	putative signal peptidase I	Best Blastp hit %3D sp|P41027|LEPC_BACCL SIGNAL PEPTIDASE I (SPASE I) (LEADER PEPTIDASE I) >gi|2126774|pir||I40175 signal peptidase I (EC 3.4.21.89) - Bacillus caldolyticus >gi|451875|gb|AAA22759.1| (L26257) signal peptidase I [Bacillus caldolyticus] >gi|809656|emb|CAA81813.1| (Z27457) signal peptidase I [Bacillus caldolyticus]	gene	gene1053	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1281
SPy_1282	SPy1282	pyk	pyk	1056375	1057877	-	putative pyruvate kinase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|Q07637|KPYK_LACLA PYRUVATE KINASE >gi|421428|pir||B40620 pyruvate kinase (EC 2.7.1.40) - Lactococcus lactis >gi|308858|gb|AAA99895.1| (L07920) ATP:pyruvate 2-O-phosphotransferase [Lactococcus lactis]	gene	gene1054	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1282
SPy_1283	SPy1283	pfk	pfk	1057940	1058953	-	putative 6-phosphofructokinase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|Q07636|K6PF_LACLA 6-PHOSPHOFRUCTOKINASE (PHOSPHOFRUCTOKINASE) (PHOSPHOHEXOKINASE) >gi|2144409|pir||JN0614 6-phosphofructokinase (EC 2.7.1.11) - Lactococcus lactis subsp. lactis (strain LM0230) >gi|308857|gb|AAA99894.1| (L07920) ATP:D-fructose 6-phosphate 1-phosphotransferase [Lactococcus lactis]	gene	gene1055	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1283
SPy_1284	SPy1284	dnaE	dnaE	1059033	1062143	-	putative DNA polymerase III (alpha subunit)	Best Blastp hit %3D sp|O34623|DP3A_BACSU DNA POLYMERASE III%2C ALPHA CHAIN >gi|7434829|pir||D69617 DNA polymerase III (alpha subunit) dnaE - Bacillus subtilis >gi|2293260|gb|AAC00338.1| (AF008220) DNA-polymerase III alpha-chain [Bacillus subtilis] >gi|2635388|emb|CAB14883.1| (Z99118) DNA polymerase III (alpha subunit) [Bacillus subtilis]	gene	gene1056	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1284
SPy_1285	SPy1285		SPy_1285	1062328	1062699	+	putative transcriptional regulator (GntR family)	Best Blastp hit %3D dbj|BAA83965.1| (AB024564) YHCF [Bacillus halodurans] >gi|10172996|dbj|BAB04102.1| (AP001508) transcriptional regulator (GntR family) [Bacillus halodurans]	gene	gene1057	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1285
SPy_1286	SPy1286		SPy_1286	1062699	1063397	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||G71842 probable ABC transporter%2C ATP-binding protein - Helicobacter pylori (strain J99) >gi|4155748|gb|AAD06727.1| (AE001542) putative ABC transporter%2C ATP-binding protein [Helicobacter pylori J99]	gene	gene1058	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1286
SPy_1287	SPy1287		SPy_1287	1063407	1064192	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1059	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1287
SPy_1288	SPy1288		SPy_1288	1064319	1064933	-	hypothetical protein	Best Blastp hit %3D pir||E69833 conserved hypothetical protein yhjE - Bacillus subtilis >gi|2226177|emb|CAA74467.1| (Y14081) hypothetical protein [Bacillus subtilis] >gi|2633384|emb|CAB12888.1| (Z99109) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1060	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1288
SPy_1290	SPy1290		SPy_1290	1065674	1066294	+	hypothetical protein	Best Blastp hit %3D emb|CAA76857.1| (Y17797) hypothetical protein [Enterococcus faecalis]	gene	gene1062	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1290
SPy_1291	SPy1291	glgP	glgP	1066551	1068815	-	putative glycogen phosphorylase	Best Blastp hit %3D gb|AAF39800.1| (AC006636) contains similarity to Pfam domain PF00343 (phosphorylase)%2C Score%3D1562.5%2C E-value%3D0%2C N%3D1 [Caenorhabditis elegans]	gene	gene1063	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1291
SPy_1292	SPy1292	malM	malM	1068850	1070343	-	putative 4-alpha-glucanotransferase	Best Blastp hit %3D sp|Q59266|MALQ_CLOBU 4-ALPHA-GLUCANOTRANSFERASE (AMYLOMALTASE) (DISPROPORTIONATING ENZYME) (D-ENZYME) >gi|598094|gb|AAB84229.1| (L37874) 4-alpha-glucanotransferase [Clostridium butyricum]	gene	gene1064	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1292
SPy_1293	SPy1293	malR	malR	1070458	1071477	-	putative maltose operon transcriptional repressor	Best Blastp hit %3D dbj|BAB06642.1| (AP001517) transcriptional regulator involved in carbon catabolite control [Bacillus halodurans]	gene	gene1065	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1293
SPy_1294	SPy1294		SPy_1294	1071723	1072970	+	putative maltose/maltodextrin-binding protein	Best Blastp hit %3D sp|P29850|MALX_STRPN MALTOSE/MALTODEXTRIN-BINDING PROTEIN PRECURSOR >gi|479206|pir||S32569 malX protein - Streptococcus pneumoniae >gi|153723|gb|AAA26925.1| (L08611) MalX [Streptococcus pneumoniae]	gene	gene1066	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1294
SPy_1295	SPy1295	malF	malF	1073244	1074605	+	putative maltose/maltodextrin ABC transport system (permease)	Best Blastp hit %3D pir||S63615 malF protein homolog cymF - Klebsiella oxytoca >gi|854233|emb|CAA60005.1| (X86014) cymF [Klebsiella oxytoca]	gene	gene1067	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1295
SPy_1296	SPy1296	malG	malG	1074605	1075441	+	putative maltose/maltodextrin ABC transport system (permease)	Best Blastp hit %3D pir||S63616 malG protein homolog cymG - Klebsiella oxytoca >gi|854234|emb|CAA60006.1| (X86014) cymG [Klebsiella oxytoca]	gene	gene1068	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1296
SPy_1297	SPy1297		SPy_1297	1075596	1076396	+	putative transcription regulator (LacI family)	Best Blastp hit %3D pir||B69853 transcription regulator LacI family homolog yjmH - Bacillus subtilis >gi|2612909|gb|AAC46333.1| (AF015825) lacI repressor-like protein [Bacillus subtilis] >gi|2633591|emb|CAB13094.1| (Z99110) similar to transcriptional regulator (LacI family) [Bacillus subtilis]	gene	gene1069	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1297
SPy_1298	SPy1298	malA	malA	1076512	1077327	-	putative maltodextrose utilization protein	Best Blastp hit %3D pir||B70034 hypothetical protein yvdJ - Bacillus subtilis >gi|1945669|emb|CAB08039.1| (Z94043) hypothetical protein [Bacillus subtilis] >gi|2635971|emb|CAB15463.1| (Z99121) yvdJ [Bacillus subtilis]	gene	gene1070	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1298
SPy_1299	SPy1299	malD	malD	1077349	1078209	-	putative maltodextrin transport system permease	Best Blastp hit %3D sp|Q04699|MALD_STRPN MALTODEXTRIN TRANSPORT SYSTEM PERMEASE PROTEIN MALD >gi|479208|pir||S32571 malD protein - Streptococcus pneumoniae >gi|153725|gb|AAA26927.1| (L08611) MalD [Streptococcus pneumoniae]	gene	gene1071	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1299
SPy_1301	SPy1301	malC	malC	1078206	1079513	-	maltodextrin transport system permease	Best Blastp hit %3D pir||H70033 maltodextrin transport system permease homolog yvdH - Bacillus subtilis >gi|1945667|emb|CAB08037.1| (Z94043) hypothetical protein [Bacillus subtilis] >gi|2635973|emb|CAB15465.1| (Z99121) similar to maltodextrin transport system permease [Bacillus subtilis]	gene	gene1072	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1301
SPy_1302	SPy1302	amyA	amyA	1079588	1081723	-	putative cyclomaltodextrin glucanotransferase	Best Blastp hit %3D pdb|1CIU| Thermostable Cgtase From Thermoanaerobacterium Thermosulfurigenes Em1 At Ph 8.0. >gi|3318982|pdb|1A47| Cgtase From Thermoanaerobacterium Thermosulfurigenes Em1 In Complex With A Maltohexaose Inhibitor	gene	gene1073	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1302
SPy_1304	SPy1304	amyB	amyB	1081749	1083452	-	putative cyclomaltodextrinase	Best Blastp hit %3D sp|P38940|NEPU_BACST NEOPULLULANASE >gi|98215|pir||A37008 neopullulanase (EC 3.2.1.135) - Bacillus stearothermophilus >gi|541633|gb|AAA22622.1| (M28138) neopullulanase [Bacillus stearothermophilus]	gene	gene1074	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1304
SPy_1306	SPy1306	malX	malX	1083618	1084877	-	maltose/maltodextrin-binding protein	Best Blastp hit %3D gb|AAA26922.1| (J01796) phosphorylase [Streptococcus pneumoniae]	gene	gene1075	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1306
SPy_1308	SPy1308		SPy_1308	1085492	1086475	-	putative esterase	Best Blastp hit %3D sp|Q01109|BAH_STRHY ACETYL-HYDROLASE >gi|1019658|gb|AAA79277.1| (M64783) acetyl-hydrolase [Streptomyces hygroscopicus]	gene	gene1076	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1308
SPy_1309	SPy1309	dltD	dltD	1086506	1087756	-	putative extramembranal protein	Best Blastp hit %3D gb|AAC29041.1| (AF050517) unknown [Streptococcus mutans]	gene	gene1077	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1309
SPy_1310	SPy1310	dltC	dltC	1087749	1087988	-	putative D-alanyl carrier protein	Best Blastp hit %3D sp|P55153|DLTC_LACCA D-ALANYL CARRIER PROTEIN (DCP) >gi|1161934|gb|AAB17659.1| (U43894) DltC [Lactobacillus casei] >gi|6456612|gb|AAF09203.1|AF192553_3 (AF192553) DltC [Lactobacillus rhamnosus]	gene	gene1078	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1310
SPy_1311	SPy1311	dltB	dltB	1088006	1089262	-	putative integral membrane protein	Best Blastp hit %3D gb|AAC29039.1| (AF050517) unknown [Streptococcus mutans] >gi|2981429|gb|AAC06285.1| (AF049357) Glg2 [Streptococcus mutans]	gene	gene1079	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1311
SPy_1312	SPy1312	dltA	dltA	1089259	1090797	-	putative D-alanine-D-alanyl carrier protein ligase	Best Blastp hit %3D gb|AAC06284.1| (AF049357) Glg1 [Streptococcus mutans]	gene	gene1080	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1312
SPy_1314	SPy1314	uvrB	uvrB	1091216	1093207	-	putative excinuclease ABC (subunit B)	Best Blastp hit %3D sp|P37954|UVRB_BACSU EXCINUCLEASE ABC SUBUNIT B (DINA PROTEIN) >gi|7443925|pir||G69729 excinuclease ABC chain B - Bacillus subtilis >gi|2618841|gb|AAC67270.1| (AF017113) excinuclease ABC subunit B [Bacillus subtilis] >gi|2636043|emb|CAB15534.1| (Z99122) excinuclease ABC (subunit B) [Bacillus subtilis]	gene	gene1081	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1314
SPy_1315	SPy1315		SPy_1315	1093400	1095574	+	hypothetical protein	Best Blastp hit %3D pir||S77250 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1652664|dbj|BAA17584.1| (D90907) glutamine-binding periplasmic protein [Synechocystis sp.]	gene	gene1082	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1315
SPy_1316	SPy1316		SPy_1316	1095574	1096314	+	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB05182.1| (AP001512) ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1083	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1316
SPy_1319	SPy1319		SPy_1319	1096614	1097990	-		This gene contains a confirmed point mutation that introduces a stop codon within the coding region%3B Best Blast Hit %3D gi|12723026|gb|AAK04272.1|AE006255_2 (AE006255) cellobiose-specific PTS system IIC component (EC 2.7.1.69)[Lactococcus lactis subsp. lactis]	gene	gene1084	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1319
SPy_1322	SPy1322		SPy_1322	1098168	1098617	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1085	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1322
SPy_1323	SPy1323		SPy_1323	1098614	1098949	-	putative PTS enzyme III	Best Blastp hit %3D sp|Q45402|PTCA_BACST PTS SYSTEM%2C CELLOBIOSE-SPECIFIC IIA COMPONENT (EIIA-CEL) (CELLOBIOSE-PERMEASE IIA COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C A COMPONENT) (EIII-CEL) >gi|541385|pir||E49898 cellobiose phosphotransferase system celD - Bacillus stearothermophilus >gi|466476|gb|AAA17392.1| (U07818) cellobiose phosphotransferase enzyme III [Bacillus stearothermophilus]	gene	gene1086	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1323
SPy_1324	SPy1324		SPy_1324	1098952	1099263	-	putative PTS system enzyme II	Best Blastp hit %3D dbj|BAB04628.1| (AP001510) PTS system%2C cellobiose-specific enzyme II%2C B component (EIIA-cell) [Bacillus halodurans]	gene	gene1087	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1324
SPy_1325	SPy1325		SPy_1325	1099286	1101280	-	putative transcriptional antiterminator (BglG family)	Best Blastp hit %3D pir||F69848 transcription antiterminator BglG family homolog yjdC - Bacillus subtilis >gi|2633554|emb|CAB13057.1| (Z99110) similar to transcriptional antiterminator (BglG family) [Bacillus subtilis]	gene	gene1088	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1325
SPy_1326	SPy1326		SPy_1326	1101386	1102480	-	hypothetical protein	Best Blastp hit %3D dbj|BAB07292.1| (AP001519) unknown conserved protein in others [Bacillus halodurans]	gene	gene1089	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1326
SPy_1328	SPy1328	bglA.2	bglA.2	1102489	1103889	-	putative beta-glucosidase	Best Blastp hit %3D dbj|BAB07637.1| (AP001520) beta-glucosidase [Bacillus halodurans]	gene	gene1090	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1328
SPy_1329	SPy1329		SPy_1329	1104114	1104611	+	hypothetical protein	Best Blastp hit %3D sp|Q57425|YA7B_HAEIN HYPOTHETICAL PROTEIN HI1077.1 >gi|1574631|gb|AAC22744.1| (U32788) H. influenzae predicted coding region HI1077.1 [Haemophilus influenzae Rd]	gene	gene1091	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1329
SPy_1332	SPy1332		SPy_1332	1104815	1104973	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1092	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1332
SPy_1333	SPy1333		SPy_1333	1105042	1106355	-	putative GTP-binding protein	Best Blastp hit %3D dbj|BAB04932.1| (AP001511) GTP-binding protein involved in initiation of sporulation [Bacillus halodurans]	gene	gene1093	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1333
SPy_1335	SPy1335		SPy_1335	1106782	1107297	+	conserved hypothetical protein - transposon IS861 associated	Best Blastp hit %3D gb|AAF73805.1|AF154034_2 (AF154034) hypothetical protein [Streptococcus pneumoniae]	gene	gene1094	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1335
SPy_1336	SPy1336		SPy_1336	1107318	1108124	+	putative transposase - IS861 associated	Best Blastp hit %3D pir||A33595 probable transposase - Streptococcus agalactiae insertion sequence IS861 >gi|1196922|gb|AAA88575.1| (M22449) unknown protein [Streptococcus agalactiae]	gene	gene1095	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1336
SPy_1337	SPy1337	rsuA	rsuA	1108173	1108907	-	putative 16S pseudouridylate synthase	Best Blastp hit %3D dbj|BAB06992.1| (AP001518) 16S pseudouridylate synthase [Bacillus halodurans]	gene	gene1096	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1337
SPy_1339	SPy1339		SPy_1339	1109019	1109384	+	hypothetical protein	Best Blastp hit %3D pir||F72358 hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981099|gb|AAD35666.1|AE001733_3 (AE001733) hypothetical protein [Thermotoga maritima]	gene	gene1097	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1339
SPy_1340	SPy1340		SPy_1340	1109504	1110724	-	hypothetical protein	Best Blastp hit %3D pir||T47026 hypothetical protein [imported] - Yersinia pestis >gi|4106614|emb|CAA21369.1| (AL031866) ORF46%2C len%3D 409 aa%2C similar to many transport protein%2C eg: AEMML_1 Ralstonia eutropha%2C (428 aa)%2C 44.2 %25 identity in 407 aa overlap%2C Fasta scores: opt: 1217E(): 0%2C or U32790_4 Haemophilus influenzae Rd section 1 (407 aa)%2C 33.0%25 identity in 40>	gene	gene1098	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1340
SPy_1343	SPy1343		SPy_1343	1111026	1112582	+	hypothetical protein	Best Blastp hit %3D gb|AAF37887.1|AF234269_1 (AF234269) outer membrane protein A [Escherichia coli]	gene	gene1099	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1343
SPy_1344	SPy1344		SPy_1344	1112689	1113090	-	hypothetical protein	Best Blastp hit %3D sp|P76084|PAAI_ECOLI PHENYLACETIC ACID DEGRADATION PROTEIN PAAI >gi|7430237|pir||G64890 conserved hypothetical protein b1396 - Escherichia coli >gi|1787662|gb|AAC74478.1| (AE000236) orf%2C hypothetical protein [Escherichia coli] >gi|2764831|emb|CAA66098.1| (X97452) paaI [Escherichia coli]	gene	gene1100	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1344
SPy_1345	SPy1345		SPy_1345	1113175	1113687	-	hypothetical protein	Best Blastp hit %3D pir||D71475 probable AMP nucleosidase - Chlamydia trachomatis (serotype D%2C strain UW3/Cx) >gi|3329212|gb|AAC68346.1| (AE001347) AMP Nucleosidase [Chlamydia trachomatis]	gene	gene1101	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1345
SPy_1346	SPy1346		SPy_1346	1113992	1115380	-	putative RNA methyltransferase	Best Blastp hit %3D pir||E69793 RNA methyltransferase homolog yefA - Bacillus subtilis >gi|2632987|emb|CAB12493.1| (Z99107) alternate gene name: yerS~similar to RNA methyltransferase [Bacillus subtilis]	gene	gene1102	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1346
SPy_1350	SPy1350	psr	psr	1115429	1116880	-	putative PBP 5 synthesis repressor	Best Blastp hit %3D gb|AAC62817.1| (U42211) PBP 5 synthesis repressor [Enterococcus hirae]	gene	gene1103	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1350
SPy_1351	SPy1351	aroK	aroK	1117088	1117579	-	putative shikimate kinase	Best Blastp hit %3D pir||D82693 shikimate kinase XF1335 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106332|gb|AAF84144.1|AE003966_5 (AE003966) shikimate kinase [Xylella fastidiosa]	gene	gene1104	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1351
SPy_1352	SPy1352	aroA	aroA	1117572	1118864	-	putative 3-phosphoshikimate 1-carboxyvinyltransferase	Best Blastp hit %3D sp|P43905|AROA_LACLA 3-PHOSPHOSHIKIMATE 1-CARBOXYVINYLTRANSFERASE (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS) >gi|1075724|pir||S52580 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) - Lactococcus lactis >gi|683583|emb|CAA55180.1| (X78413) 5-enolpyruvylshikimate-3-phosphate synthase [Lactococcus lactis]	gene	gene1105	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1352
SPy_1353	SPy1353		SPy_1353	1118966	1119931	-	hypothetical protein	Best Blastp hit %3D dbj|BAB07074.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene1106	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1353
SPy_1354	SPy1354	map	map	1119933	1120793	-	putative methionine aminopeptidase	Best Blastp hit %3D sp|Q9Z9J4|AMPM_BACHD METHIONINE AMINOPEPTIDASE (MAP) (PEPTIDASE M) >gi|11264635|pir||T44405 methionyl aminopeptidase (EC 3.4.11.18) map [imported] - Bacillus halodurans >gi|4512426|dbj|BAA75293.1| (AB017508) map homologue (identity of 81%25 to B. subtilis) [Bacillus halodurans] >gi|10172768|dbj|BAB03875.1| (AP001507) methionine aminopeptidase [Bacillus halodurans]	gene	gene1107	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1354
SPy_1355	SPy1355		SPy_1355	1120809	1122092	-	hypothetical protein	Best Blastp hit %3D pir||A69998 hypothetical protein ytoI - Bacillus subtilis >gi|2293258|gb|AAC00336.1| (AF008220) YtoI [Bacillus subtilis] >gi|2635392|emb|CAB14887.1| (Z99118) ytoI [Bacillus subtilis]	gene	gene1108	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1355
SPy_1356	SPy1356		SPy_1356	1122101	1122643	-	putative acetyl transferase	Best Blastp hit %3D emb|CAA03913.1| (AJ000084) putative acetyl transferase [Proteus mirabilis]	gene	gene1109	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1356
SPy_1357	SPy1357	grab	grab	1122881	1123534	-	protein GRAB (protein G-related alpha 2M-binding protein)	Best Blastp hit %3D gb|AAD26340.1|AF124401_1 (AF124401) GRAB precursor [Streptococcus pyogenes]	gene	gene1110	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1357
SPy_1358	SPy1358	murZ	murZ	1123892	1125151	-	putative UDP-N-acetylglucosamine 1-carboxyvinyltransferase	Best Blastp hit %3D sp|P19670|MUA2_BACSU UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE 2 (ENOYLPYRUVATE TRANSFERASE) (UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE) (EPT) >gi|2127262|pir||G32354 UDP-N-acetylglucosamine 1-carboxyvinyltransferase (EC 2.5.1.7) murZ - Bacillus subtilis >gi|853767|emb|CAA89875.1| (Z49782) UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Bacillus subtilis] >gi|2636235|emb|CAB15727.1| (Z99122) UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Bacillus subtilis] >gi|2636247|emb|CAB15738.1| (Z99123) UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Bacillus subtilis]	gene	gene1111	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1358
SPy_1359	SPy1359	metK	metK	1125325	1126521	-	S-adenosylmethionine synthetase	Best Blastp hit %3D sp|P54419|METK_BACSU S-ADENOSYLMETHIONINE SYNTHETASE (METHIONINE ADENOSYLTRANSFERASE) (ADOMET SYNTHETASE) >gi|7434008|pir||D69657 methionine adenosyltransferase (EC 2.5.1.6) - Bacillus subtilis >gi|2293164|gb|AAC00242.1| (AF008220) SAM synthase [Bacillus subtilis] >gi|2635539|emb|CAB15033.1| (Z99119) S-adenosylmethionine synthetase [Bacillus subtilis]	gene	gene1112	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1359
SPy_1361	SPy1361	inlA	inlA	1127058	1129436	-	putative internalin A precursor	Best Blastp hit %3D sp|P25146|INLA_LISMO INTERNALIN A PRECURSOR >gi|487052|pir||S37387 internalin A precursor - Listeria monocytogenes	gene	gene1113	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1361
SPy_1362	SPy1362	birA	birA	1129640	1130581	+	putative biotin operon repressor	Best Blastp hit %3D dbj|BAB05404.1| (AP001512) transcriptional repressor of the biotin operon [Bacillus halodurans]	gene	gene1114	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1362
SPy_1363	SPy1363		SPy_1363	1130556	1130828	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1115	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1363
SPy_1364	SPy1364	dnaX	dnaX	1130854	1132524	-	DNA polymerase III subunits gamma / tau	Best Blastp hit %3D gb|AAF98349.1| (AF280765) DNA polymerase III beta subunit [Streptococcus pyogenes]	gene	gene1116	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1364
SPy_1365	SPy1365		SPy_1365	1132524	1133021	-	hypothetical protein	Best Blastp hit %3D gb|AAG06210.1|AE004709_3 (AE004709) conserved hypothetical protein [Pseudomonas aeruginosa]	gene	gene1117	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1365
SPy_1366	SPy1366		SPy_1366	1133166	1133975	+	hypothetical protein	Best Blastp hit %3D emb|CAC08406.1| (AL392177) putative integral membrane protein [Streptomyces coelicolor]	gene	gene1118	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1366
SPy_1367	SPy1367		SPy_1367	1134028	1134291	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1119	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1367
SPy_1368	SPy1368	udk	udk	1134371	1134997	-	putative uridine kinase	Best Blastp hit %3D dbj|BAB04994.1| (AP001511) uridine kinase [Bacillus halodurans]	gene	gene1120	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1368
SPy_1369	SPy1369	deaD2	deaD2	1135095	1136180	+	putative RNA helicase	Best Blastp hit %3D pir||C69813 RNA helicase homolog yfmL - Bacillus subtilis >gi|2443255|dbj|BAA22326.1| (D86417) YfmL [Bacillus subtilis] >gi|2633067|emb|CAB12572.1| (Z99108) similar to RNA helicase [Bacillus subtilis]	gene	gene1121	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1369
SPy_1370	SPy1370		SPy_1370	1136291	1137565	-	putative deacetylase	Best Blastp hit %3D pir||G69849 endo-1%2C4-beta-xylanase homolog yjeA - Bacillus subtilis >gi|2612882|gb|AAC46306.1| (AF015825) NodB-like protein [Bacillus subtilis] >gi|2633564|emb|CAB13067.1| (Z99110) similar to endo-1%2C4-beta-xylanase [Bacillus subtilis]	gene	gene1122	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1370
SPy_1371	SPy1371	gapN	gapN	1137660	1139087	-	putative NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB05956.1| (AP001514) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase [Bacillus halodurans]	gene	gene1123	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1371
SPy_1372	SPy1372	pstI	pstI	1139272	1141005	-	putative phosphoenolpyruvate:sugar phosphotransferase system enzyme I	Best Blastp hit %3D sp|P30299|PT1_STRSL PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE (PHOSPHOTRANSFERASE SYSTEM%2C ENZYME I) >gi|322087|pir||JC1375 phosphotransferase system enzyme I (EC 2.7.3.9) - Streptococcus salivarius >gi|153615|gb|AAA26873.1| (M81756) phosphoenolpyruvate:sugar phosphotransferase system enzyme I [Streptococcus salivarius] >gi|1583334|prf||2120381B ptsI gene [Streptococcus salivarius]	gene	gene1124	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1372
SPy_1373	SPy1373	ptsH	ptsH	1141010	1141273	-	putative phosphotransferase system phosphohistidine-containing protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P24366|PTHP_STRSL PHOSPHOCARRIER PROTEIN HPR (HISTIDINE-CONTAINING PROTEIN) >gi|480991|pir||S37585 phosphotransferase system phosphohistidine-containing protein - Streptococcus salivarius >gi|406779|emb|CAA78923.1| (Z17217) HPr [Streptococcus salivarius] >gi|739971|prf||2004268A His containing phosphocarrier protein [Streptococcus salivarius] >gi|1583333|prf||2120381A ptsH gene [Streptococcus salivarius]	gene	gene1125	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1373
SPy_1374	SPy1374	nrdH	nrdH	1141666	1141884	+	putative glutaredoxin	Best Blastp hit %3D sp|Q48708|NRDH_LACLC GLUTAREDOXIN-LIKE PROTEIN NRDH >gi|1222680|emb|CAA63372.1| (X92690) glutaredoxin-like protein [Lactococcus lactis]	gene	gene1126	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1374
SPy_1375	SPy1375	nrdE.2	nrdE.2	1141904	1144063	+	putative ribonucleotide reductase alpha-chain	Best Blastp hit %3D gb|AAD41036.1|AF112535_3 (AF112535) ribonucleotide reductase alpha-chain [Corynebacterium glutamicum]	gene	gene1127	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1375
SPy_1378	SPy1378	nrdF.2	nrdF.2	1144396	1145355	+	ribonucleotide diphosphate reductase small subunit	Best Blastp hit %3D emb|CAA70766.1| (Y09572) ribonucleotide reductase subunit R2F [Corynebacterium ammoniagenes]	gene	gene1128	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1378
SPy_1379	SPy1379		SPy_1379	1145330	1146643	+	putative chloride channel protein	Best Blastp hit %3D gb|AAF41386.1| (AE002449) chloride channel protein-related protein [Neisseria meningitidis MC58]	gene	gene1129	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1379
SPy_1380	SPy1380		SPy_1380	1146781	1147937	+		This gene contains multiple confirmed frameshift and point mutations within the coding region%3B Best Blastp hit %3D gi|97939|pir||S14450 probable transposase - Lactococcus lactis subsp. lactis insertion sequence IS1076 gi|44079|emb|CAA37193.1| (X53013) ORF1 (AA 1 - 384) [Lactococcus lactis]	gene	gene1130	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1380
SPy_1384	SPy1384		SPy_1384	1148029	1148724	-	hypothetical protein	Best Blastp hit %3D pir||S76167 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1653513|dbj|BAA18426.1| (D90914) hypothetical protein [Synechocystis sp.]	gene	gene1131	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1384
SPy_1385	SPy1385		SPy_1385	1148743	1149504	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1132	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1385
SPy_1386	SPy1386		SPy_1386	1149501	1149716	-	putative transcriptional regulator protein	Best Blastp hit %3D sp|O28481|YH93_ARCFU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR AF1793 >gi|7483936|pir||H69473 repressor protein homolog - Archaeoglobus fulgidus >gi|2648767|gb|AAB89470.1| (AE000979) repressor protein [Archaeoglobus fulgidus]	gene	gene1133	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1386
SPy_1389	SPy1389	alaS	alaS	1150077	1152695	-	putative alanyl-tRNA synthetase	Best Blastp hit %3D sp|O34526|SYA_BACSU ALANYL-TRNA SYNTHETASE (ALANINE-TRNA LIGASE) (ALARS) >gi|7437617|pir||A69584 alanine-tRNA ligase (EC 6.1.1.7) alaS - Bacillus subtilis >gi|2635186|emb|CAB14682.1| (Z99117) alanyl-tRNA synthetase [Bacillus subtilis] >gi|2635204|emb|CAB14699.1| (Z99118) alanyl-tRNA synthetase [Bacillus subtilis]	gene	gene1134	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1389
SPy_1390	SPy1390		SPy_1390	1153082	1154137	-	putative protease maturation protein	Best Blastp hit %3D sp|P15294|PRTM_LACLA PROTEASE MATURATION PROTEIN PRECURSOR >gi|79978|pir||S08083 probable protein export protein prtM precursor - Lactococcus lactis subsp. cremoris (strain NCDO 763) plasmid pLP763 >gi|47198|emb|CAA32349.1| (X14130) ORF (AA 1 to 299) [Lactococcus lactis subsp. cremoris]	gene	gene1135	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1390
SPy_1391	SPy1391		SPy_1391	1154200	1154907	-	putative methyltransferase	Best Blastp hit %3D gb|AAC46080.1| (AF016233) methyltransferase [Enterococcus faecalis]	gene	gene1136	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1391
SPy_1392	SPy1392		SPy_1392	1154973	1156169	-	putative oxalate:formate antiporter	Best Blastp hit %3D dbj|BAB06247.1| (AP001515) unknown conserved protein in others [Bacillus halodurans]	gene	gene1137	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1392
SPy_1393	SPy1393	pepB	pepB	1156545	1158350	-	putative oligopeptidase	Best Blastp hit %3D sp|P54124|PEF1_LACLA OLIGOENDOPEPTIDASE F%2C PLASMID >gi|2126618|pir||A55485 ligoendopeptidase F - Lactococcus lactis >gi|510140|emb|CAA83534.1| (Z32522) ligoendopeptidase F [Lactococcus lactis]	gene	gene1138	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1393
SPy_1395	SPy1395		SPy_1395	1158363	1159325	-	putative transcription factor	Best Blastp hit %3D gb|AAC23746.1| (AF052209) competence protein [Streptococcus pneumoniae]	gene	gene1139	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1395
SPy_1398	SPy1398		SPy_1398	1159751	1160335	-	putative 16S pseudouridylate synthetase	Best Blastp hit %3D emb|CAB82472.1| (Y14816) hypothetical protein [Staphylococcus aureus]	gene	gene1140	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1398
SPy_1399	SPy1399	nagB	nagB	1160454	1161158	-	putative N-acetylglucosamine-6-phosphate isomerase	Best Blastp hit %3D sp|O35000|NAGB_BACSU GLUCOSAMINE-6-PHOSPHATE ISOMERASE (GLUCOSAMINE-6-PHOSPHATE DEAMINASE) (GNPDA) (GLCN6P DEAMINASE) >gi|7437376|pir||B69664 N-acetylglucosamine-6-phosphate isomerase nagB - Bacillus subtilis >gi|2618855|gb|AAC67284.1| (AF017113) glucosamine-6-P isomerase [Bacillus subtilis] >gi|2636015|emb|CAB15507.1| (Z99121) N-acetylglucosamine-6-phosphate isomerase [Bacillus subtilis]	gene	gene1141	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1399
SPy_1400	SPy1400	queA	queA	1161360	1162388	+	putative S-adenosylmethionine-tRNA ribosyltransferase-isomerase	Best Blastp hit %3D sp|O32054|QUEA_BACSU S-ADENOSYLMETHIONINE:TRNA RIBOSYLTRANSFERASE-ISOMERASE (QUEUOSINE BIOSYNTHESIS PROTEIN QUEA) >gi|7448367|pir||A69688 S-adenosylmethionine-tRNA ribosyltransferase-isomerase (EC 5.4.99.-) queA [similarity] - Bacillus subtilis >gi|2635237|emb|CAB14732.1| (Z99118) S-adenosylmethionine tRNA ribosyltransferase [Bacillus subtilis] >gi|6977807|emb|CAB75332.1| (Y15896) QueA protein [Bacillus subtilis]	gene	gene1142	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1400
SPy_1401	SPy1401		SPy_1401	1162395	1163615	+	hypothetical protein	Best Blastp hit %3D gb|AAF56254.1| (AE003746) CG5524 gene product [Drosophila melanogaster]	gene	gene1143	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1401
SPy_1402	SPy1402		SPy_1402	1163729	1164319	-	hypothetical protein	Best Blastp hit %3D sp|Q59514|BLA1_MORCA BETA-LACTAMASE BRO-1 PRECURSOR (PENICILLINASE) >gi|1224070|gb|AAA92126.1| (U49269) Beta-lactamase BRO-1 [Moraxella catarrhalis]	gene	gene1144	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1402
SPy_1404	SPy1404		SPy_1404	1164316	1164564	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1145	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1404
SPy_1405	SPy1405		SPy_1405	1164549	1164776	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1146	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1405
SPy_1406	SPy1406	sodA	sodA	1164943	1165548	-	superoxide dismutase (Fe/Mn)	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D gb|AAB17024.1| (U43776) superoxide dismutase [Streptococcus pyogenes]	gene	gene1147	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1406
SPy_1407	SPy1407	holA	holA	1165645	1166685	-	DNA polymerase III delta subunit	Best Blastp hit %3D emb|CAA72898.1| (Y12224) hypothetical protein [Streptococcus agalactiae]	gene	gene1148	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1407
SPy_1408	SPy1408	comEC	comEC	1166756	1168999	-	putative competence protein	Best Blastp hit %3D dbj|BAA12454.1| (D84432) ComEC [Bacillus subtilis] >gi|2635003|emb|CAB14499.1| (Z99117) putative integral membrane protein [Bacillus subtilis]	gene	gene1149	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1408
SPy_1409	SPy1409	comEA	comEA	1168980	1169642	-	putative competence protein	Best Blastp hit %3D sp|P39694|CME1_BACSU COME OPERON PROTEIN 1 >gi|541403|pir||S39863 late competence operon required for DNA binding and uptake comEA - Bacillus subtilis >gi|289260|gb|AAC36905.1| (L15202) comE ORF1 [Bacillus subtilis] >gi|1303796|dbj|BAA12452.1| (D84432) ComEA [Bacillus subtilis] >gi|2635005|emb|CAB14501.1| (Z99117) integral membrane protein [Bacillus subtilis]	gene	gene1150	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1409
SPy_1410	SPy1410		SPy_1410	1169842	1170660	-	putative 1-acylglycerol-3-phosphate O-acyltransferase	Best Blastp hit %3D pir||H75254 probable 1-acylglycerol-3-phosphate O-acyltransferase (EC 2.3.1.51) - Deinococcus radiodurans (strain R1) >gi|6460414|gb|AAF12125.1|AE002088_2 (AE002088) conserved hypothetical protein [Deinococcus radiodurans]	gene	gene1151	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1410
SPy_1411	SPy1411		SPy_1411	1170700	1171476	+	hypothetical protein	Best Blastp hit %3D sp|P37543|YABB_BACSU HYPOTHETICAL 28.3 KD PROTEIN IN XPAC-ABRB INTERGENIC REGION >gi|2127031|pir||S66064 conserved hypothetical protein yabB - Bacillus subtilis >gi|467424|dbj|BAA05270.1| (D26185) unknown [Bacillus subtilis] >gi|2632301|emb|CAB11810.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1152	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1411
SPy_1412	SPy1412		SPy_1412	1171466	1171744	+	hypothetical protein	Best Blastp hit %3D emb|CAA50274.1| (X70925) y98 [Pediococcus acidilactici]	gene	gene1153	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1412
SPy_1414	SPy1414		SPy_1414	1171768	1173768	-	putative cation (K+) transport protein	Best Blastp hit %3D gb|AAG04306.1|AE004526_1 (AE004526) potassium uptake protein Kup [Pseudomonas aeruginosa]	gene	gene1154	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1414
SPy_1415	SPy1415	deaD	deaD	1173896	1175515	-	putative ATP-dependent RNA helicase	Best Blastp hit %3D pir||D69772 ATP-dependent RNA helicase homolog ydbR - Bacillus subtilis >gi|1881268|dbj|BAA19295.1| (AB001488) ATP-DEPENDENT RNA HELICASE DEAD HOMOLOG. [Bacillus subtilis] >gi|2632758|emb|CAB12265.1| (Z99106) similar to ATP-dependent RNA helicase [Bacillus subtilis]	gene	gene1155	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1415
SPy_1416	SPy1416	prfC	prfC	1175822	1177366	-	putative peptide-chain-release factor 3	Best Blastp hit %3D sp|P73473|RF3_SYNY3 PEPTIDE CHAIN RELEASE FACTOR 3 (RF-3) >gi|7470767|pir||S77410 peptide-chain-release factor 3 - Synechocystis sp. (strain PCC 6803) >gi|1652592|dbj|BAA17513.1| (D90906) peptide-chain-release factor 3 [Synechocystis sp.]	gene	gene1156	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1416
SPy_1419	SPy1419		SPy_1419	1177614	1178309	-	hypothetical protein	Best Blastp hit %3D sp|P25149|YWAF_BACSU HYPOTHETICAL 27.3 KD PROTEIN IN TYRZ-SACY INTERGENIC REGION (ORF1) >gi|98362|pir||S16424 hypothetical protein ywaF - Bacillus subtilis >gi|580865|emb|CAA51567.1| (X73124) ipa-11d [Bacillus subtilis] >gi|580945|emb|CAA36722.1| (X52480) ORF1 [Bacillus subtilis] >gi|2636379|emb|CAB15870.1| (Z99123) alternate gene name: ipa-11d [Bacillus subtilis]	gene	gene1157	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1419
SPy_1420	SPy1420	murF	murF	1178389	1179780	-	putative D-Ala-D-Ala adding enzyme	Best Blastp hit %3D sp|P96613|MURF_BACSU UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2%2C 6-DIAMINOPIMELATE-D-ALANYL-D-ALANYL LIGASE (UDP-MURNAC-PENTAPEPTIDE SYNTHETASE) (D-ALANYL-D-ALANINE-ADDING ENZYME) >gi|7475973|pir||F69662 UDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C 6-diaminopimelate-D-al murF - Bacillus subtilis >gi|1881267|dbj|BAA19294.1| (AB001488) PROBABLE UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2%2C 6-DIAMINOLIGASE (EC 6.3.2.15). [Bacillus subtilis] >gi|2632757|emb|CAB12264.1| (Z99106) UDP-N-acetylmuramoylalanyl-D-glutamyl-2%2C6- diaminopimelate-D-alanyl-D-alanyl ligase [Bacillus subtilis]	gene	gene1158	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1420
SPy_1421	SPy1421	ddlA	ddlA	1179971	1181017	-	putative D-ala%2CD-ala ligase	Best Blastp hit %3D emb|CAB64475.1| (AJ243056) D-ala%2CD-ala ligase [Streptococcus pneumoniae] >gi|6634584|emb|CAB64479.1| (AJ243057) D-ala%2CD-ala ligase [Streptococcus pneumoniae]	gene	gene1159	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1421
SPy_1422	SPy1422	recR	recR	1181118	1181714	-	putative recombination protein	Best Blastp hit %3D emb|CAB64458.1| (AJ243052) recombination protein [Streptococcus pneumoniae] >gi|6634563|emb|CAB64462.1| (AJ243053) recombination protein [Streptococcus pneumoniae] >gi|6634568|emb|CAB64466.1| (AJ243054) recombination protein [Streptococcus pneumoniae]	gene	gene1160	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1422
SPy_1423	SPy1423		SPy_1423	1181761	1181952	-			gene	gene1161	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1423
SPy_1424	SPy1424		SPy_1424	1182513	1183292	-	putative formate dehydrogenase	Best Blastp hit %3D gb|AAF04741.1| (AF102170) unknown [Listeria monocytogenes]	gene	gene1162	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1424
SPy_1425	SPy1425		SPy_1425	1183416	1183958	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1163	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1425
SPy_1427	SPy1427		SPy_1427	1184119	1184640	-	putative transcriptional regulator	Best Blastp hit %3D dbj|BAB04935.1| (AP001511) transcriptional regulator [Bacillus halodurans]	gene	gene1164	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1427
SPy_1429	SPy1429	gpmA	gpmA	1184747	1185442	-	putative phosphoglycerate mutase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||F81064 phosphoglycerate mutase NMB1604 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7226853|gb|AAF41956.1| (AE002510) phosphoglycerate mutase [Neisseria meningitidis MC58]	gene	gene1165	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1429
SPy_1432	SPy1432	pyrD	pyrD	1185681	1186616	+	putative dihydroorotate dehydrogenase	Best Blastp hit %3D sp|Q9X9S0|PYRD_STRPN DIHYDROOROTATE DEHYDROGENASE (DIHYDROOROTATE OXIDASE) (DHODEHASE) (DHODASE) (DHOD) >gi|5578893|emb|CAB51330.1| (AJ131985) dihydroorotate dehydrogenase [Streptococcus pneumoniae]	gene	gene1166	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1432
SPy_1434	SPy1434		SPy_1434	1186916	1188778	-	putative heavy metal-transporting ATPase	Best Blastp hit %3D pir||F69869 heavy metal-transporting ATPase homolog ykvW - Bacillus subtilis >gi|2633756|emb|CAB13258.1| (Z99111) similar to heavy metal-transporting ATPase [Bacillus subtilis]	gene	gene1167	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1434
SPy_1436	SPy1436	mf3	mf3	1189723	1190529	+	putative deoxyribonuclease	Best Blastp hit %3D emb|CAA59264.1| (X84793) streptodornase [Streptococcus pyogenes]	gene	gene1168	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1436
SPy_1437	SPy1437		SPy_1437	1190749	1191234	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1169	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1437
SPy_1438	SPy1438		SPy_1438	1191304	1192509	-	hypothetical protein	Best Blastp hit %3D gb|AAD42920.1|U12817_14 (U12817) polar FlgJ flagellar homolog [Vibrio parahaemolyticus]	gene	gene1170	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1438
SPy_1440	SPy1440		SPy_1440	1192625	1192852	-	putative holin - phage associated	Best Blastp hit %3D gi|9632912 orf87 gp [Streptococcus thermophilus bacteriophage Sfi19] >gi|9632956|ref|NP_049984.1| orf87 gp [Streptococcus thermophilus bacteriophage Sfi21] >gi|7521139|pir||T09277 probable holin 87 - Streptococcus thermophilus phage Sfi19 >gi|7521140|pir||T09208 probable holin 87 - Streptococcus thermophilus phage Sfi21 >gi|2292749|emb|CAA64941.1| (X95646) holin [Streptococcus thermophilus bacteriophage Sfi21] >gi|2935680|gb|AAC39287.1| (AF115103) orf87 gp [Streptococcus thermophilus bacteriophage Sfi21] >gi|2935695|gb|AAC39301.1| (AF115102) orf87 gp [Streptococcus thermophilus bacteriophage Sfi19]	gene	gene1171	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1440
SPy_1441	SPy1441		SPy_1441	1192849	1193124	-	hypothetical protein	Best Blastp hit %3D gb|AAF58537.2| (AE003822) CG13164 gene product [Drosophila melanogaster]	gene	gene1172	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1441
SPy_1442	SPy1442		SPy_1442	1193134	1193751	-	hypothetical protein	Best Blastp hit %3D gi|9635031 gp149 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7517695|pir||T13641 hypothetical protein gp149 - Streptococcus phage phi-Sfi11 >gi|3540291|gb|AAC34418.1| (AF158600) gp149 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene1173	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1442
SPy_1443	SPy1443		SPy_1443	1193754	1194185	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1174	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1443
SPy_1444	SPy1444		SPy_1444	1194197	1195981	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04681.1| (AP001510) unknown conserved protein in others [Bacillus halodurans]	gene	gene1175	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1444
SPy_1445	SPy1445	hylP3	hylP3	1195996	1197108	-	hyaluronidase - phage associated	Best Blastp hit %3D sp|Q54699|HYAL_BPH45 HYALURONOGLUCOSAMINIDASE (HYALURONIDASE) >gi|881507|gb|AAA86895.1| (U28144) hyaluronidase [Streptococcus pyogenes]	gene	gene1176	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1445
SPy_1446	SPy1446		SPy_1446	1197108	1199066	-	hypothetical protein	Best Blastp hit %3D gi|9633054 hypothetical protein [Lactobacillus bacteriophage phi adh] >gi|5730311|emb|CAB52532.1| (AJ131519) hypothetical protein [Lactobacillus bacteriophage phi adh]	gene	gene1177	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1446
SPy_1447	SPy1447		SPy_1447	1199063	1199758	-	hypothetical protein	Best Blastp hit %3D pir||JC4319 uroporphyrin-III C-methyltransferase (EC 2.1.1.107) - Bacillus stearothermophilus >gi|1060856|dbj|BAA07562.1| (D38558) 28 kDa protein [Bacillus stearothermophilus]	gene	gene1178	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1447
SPy_1448	SPy1448		SPy_1448	1199755	1202112	-	hypothetical protein	Best Blastp hit %3D gb|AAG18638.1| (AY007505) PblA [Streptococcus mitis]	gene	gene1179	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1448
SPy_1449	SPy1449		SPy_1449	1202112	1202483	-	hypothetical protein	Best Blastp hit %3D gb|AAB18714.1| (U38906) ORF39 [Bacteriophage r1t]	gene	gene1180	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1449
SPy_1450	SPy1450		SPy_1450	1202498	1202761	-	hypothetical protein	Best Blastp hit %3D gb|AAB18713.1| (U38906) ORF38 [Bacteriophage r1t]	gene	gene1181	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1450
SPy_1451	SPy1451		SPy_1451	1202772	1203365	-	putative structural protein - phage associated	Best Blastp hit %3D gb|AAG18635.1| (AY007505) unknown [Streptococcus mitis]	gene	gene1182	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1451
SPy_1452	SPy1452		SPy_1452	1203377	1203712	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1183	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1452
SPy_1453	SPy1453		SPy_1453	1203713	1203949	-	hypothetical protein	Best Blastp hit %3D gb|AAD17580.1| (AF068845) gp12 [Mycobacteriophage TM4]	gene	gene1184	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1453
SPy_1454	SPy1454		SPy_1454	1203942	1204271	-	hypothetical protein	Best Blastp hit %3D gb|AAF84861.1|AE004022_17 (AE004022) DNA primase [Xylella fastidiosa]	gene	gene1185	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1454
SPy_1455	SPy1455		SPy_1455	1204240	1204662	-	hypothetical protein	Best Blastp hit %3D gi|6322598 Iml1p [Saccharomyces cerevisiae] >gi|1352935|sp|P47170|YJ9G_YEAST HYPOTHETICAL 182.0 KD PROTEIN IN NMD5-HOM6 INTERGENIC REGION >gi|1077919|pir||S57161 hypothetical protein YJR138w - yeast (Saccharomyces cerevisiae) >gi|1015878|emb|CAA89670.1| (Z49638) ORF YJR138w [Saccharomyces cerevisiae]	gene	gene1186	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1455
SPy_1456	SPy1456		SPy_1456	1204672	1204872	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1187	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1456
SPy_1457	SPy1457		SPy_1457	1204872	1205783	-	putative structural protein - phage associated	Best Blastp hit %3D sp|O67759|RL1_AQUAE 50S RIBOSOMAL PROTEIN L1 >gi|7440575|pir||C70466 ribosomal protein L01 - Aquifex aeolicus >gi|2984194|gb|AAC07725.1| (AE000764) ribosomal protein L01 [Aquifex aeolicus]	gene	gene1188	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1457
SPy_1459	SPy1459		SPy_1459	1205808	1206269	-	hypothetical protein	Best Blastp hit %3D gb|AAD17576.1| (AF068845) gp8 [Mycobacteriophage TM4]	gene	gene1189	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1459
SPy_1460	SPy1460		SPy_1460	1206350	1207765	-	hypothetical protein	Best Blastp hit %3D gb|AAD17572.1| (AF068845) putative terminase gp4 [Mycobacteriophage TM4]	gene	gene1190	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1460
SPy_1461	SPy1461		SPy_1461	1207875	1208141	-	hypothetical protein	Best Blastp hit %3D gb|AAA59489.1| (M27654) laminin B2 [Homo sapiens]	gene	gene1191	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1461
SPy_1462	SPy1462		SPy_1462	1208134	1208394	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1192	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1462
SPy_1463	SPy1463		SPy_1463	1208363	1208587	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1193	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1463
SPy_1464	SPy1464		SPy_1464	1208593	1210086	-	hypothetical protein	Best Blastp hit %3D gi|6755062 phosphoinositide kinase%2C fyve-containing [Mus musculus] >gi|6685475|sp|Q9Z1T6|FYV1_MOUSE FYVE FINGER-CONTAINING PHOSPHOINOSITIDE KINASE (1-PHOSPHATIDYLINOSITOL-4-PHOSPHATE KINASE) (PIP5K) (PTDINS(4)P-5-KINASE) (P235) >gi|7513655|pir||T18290 FYVE finger-containing phosphoinositide kinase - mouse >gi|4200446|gb|AAD10191.1| (AF102777) FYVE finger-containing phosphoinositide kinase [Mus musculus]	gene	gene1194	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1464
SPy_1465	SPy1465		SPy_1465	1210079	1211347	-	putative structural protein - phage associated	Best Blastp hit %3D gb|AAB18702.1| (U38906) Structural protein [Bacteriophage r1t]	gene	gene1195	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1465
SPy_1466	SPy1466		SPy_1466	1211344	1211700	-	hypothetical protein	Best Blastp hit %3D gi|9630188 unknown [Bacteriophage SPBc2] >gi|7519731|pir||T12827 hypothetical protein yonO - Bacillus subtilis phage SPBc2 >gi|2634524|emb|CAB14022.1| (Z99115) yonO [Bacillus subtilis] >gi|3025541|gb|AAC13036.1| (AF020713) unknown [Bacteriophage SPBc2]	gene	gene1196	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1466
SPy_1468	SPy1468		SPy_1468	1211849	1212193	-	hypothetical protein	Best Blastp hit %3D gb|AAB18701.1| (U38906) ORF26 [Bacteriophage r1t]	gene	gene1197	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1468
SPy_1469	SPy1469		SPy_1469	1212302	1212721	-	hypothetical protein	Best Blastp hit %3D gi|9632461 unknown [Streptococcus thermophilus bacteriophage DT1] >gi|4530181|gb|AAD21921.1| (AF085222) unknown [Streptococcus thermophilus bacteriophage DT1]	gene	gene1198	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1469
SPy_1470	SPy1470		SPy_1470	1212989	1213624	-	hypothetical protein	Best Blastp hit %3D gb|AAF43132.1|AF208055_19 (AF208055) Orf230 [bacteriophage phi31.1]	gene	gene1199	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1470
SPy_1471	SPy1471		SPy_1471	1213626	1213895	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1200	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1471
SPy_1473	SPy1473		SPy_1473	1213979	1214491	-	conserved hypotehetical protein - phage associated	Best Blastp hit %3D gi|9630627 m3 [bacteriophage bIL170] >gi|7514939|pir||T03369 gene m3 protein - Lactococcus phage bIL170 >gi|3282321|gb|AAC27240.1| (AF009630) m3 [bacteriophage bIL170]	gene	gene1201	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1473
SPy_1474	SPy1474		SPy_1474	1214488	1214901	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1202	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1474
SPy_1475	SPy1475		SPy_1475	1215006	1215803	-	hypothetical protein phage associated	Best Blastp hit %3D no blast hits	gene	gene1203	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1475
SPy_1476	SPy1476		SPy_1476	1215796	1215996	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1204	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1476
SPy_1477	SPy1477		SPy_1477	1215993	1216982	-	putative recombinase - phage associated	Best Blastp hit %3D dbj|BAB07262.1| (AP001519) phage-related protein [Bacillus halodurans]	gene	gene1205	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1477
SPy_1478	SPy1478		SPy_1478	1216982	1217314	-	hypothetical protein	Best Blastp hit %3D pir||E71481 probable swf/snf helicase - Chlamydia trachomatis (serotype D%2C strain UW3/Cx) >gi|3329163|gb|AAC68303.1| (AE001341) SWF/SNF family helicase [Chlamydia trachomatis]	gene	gene1206	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1478
SPy_1479	SPy1479		SPy_1479	1217370	1217576	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1207	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1479
SPy_1481	SPy1481		SPy_1481	1217722	1217955	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1208	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1481
SPy_1482	SPy1482		SPy_1482	1217936	1218322	-	hypothetical protein	Best Blastp hit %3D dbj|BAA11244.1| (D78182) ORF2 [Streptococcus mutans]	gene	gene1209	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1482
SPy_1482a	SPy1482a		SPy_1482a	1218448	1218811	-		This gene contains a sequence confirmed frameshift at the 5' end of the gene%3B Best Blast Hit %3D gi|12829835|gb|AAG15562.1| (AY007566) replication protein [Bacteriophage TP901-1]	gene	gene1210	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1482a
SPy_1483	SPy1483		SPy_1483	1218811	1218996	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1211	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1483
SPy_1484	SPy1484	xis	xis	1218998	1219309	-	putative excisionase	Best Blastp hit %3D emb|CAB70621.1| (AJ243106) Xis [Streptococcus thermophilus]	gene	gene1212	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1484
SPy_1485	SPy1485		SPy_1485	1219579	1219791	-	putative Cro-like repressor protein - phage associated	Best Blastp hit %3D emb|CAB53822.1| (AJ242593) putative repressor protein [Bacteriophage A118]	gene	gene1213	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1485
SPy_1486	SPy1486		SPy_1486	1219993	1220748	+	putative repressor - phage associated	Best Blastp hit %3D gi|9635682 repressor [Staphylococcus aureus prophage phiPV83] >gi|8918752|dbj|BAA97812.1| (AB044554) repressor [Staphylococcus aureus prophage phiPV83]	gene	gene1214	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1486
SPy_1487	SPy1487		SPy_1487	1220760	1221278	+	hypothetical protein	Best Blastp hit %3D sp|P40944|XYNA_CALSR ENDO-1%2C4-BETA-XYLANASE A PRECURSOR (XYLANASE A) (1%2C4-BETA-D-XYLAN XYLANOHYDROLASE A) >gi|631989|pir||S41788 endo-1%2C4-beta-xylanase (EC 3.2.1.8) - thermophilic bacterium RT8.B4 >gi|311189|gb|AAB42044.1| (L18965) xynA [Caldicellulosiruptor sp. Rt8B.4]	gene	gene1215	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1487
SPy_1488	SPy1488	int2	int2	1221402	1222544	+	putative integrase - phage associated	Best Blastp hit %3D gi|9635193 integrase [bacteriophage phi PVL] >gi|7444572|pir||T00162 integrase - Staphylococcus aureus phage phi PVL >gi|3341936|dbj|BAA31902.1| (AB009866) integrase [bacteriophage phi PVL]	gene	gene1216	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1488
SPy_1489	SPy1489	hlpA	hlpA	1222632	1222907	-	histone-like DNA-binding protein	Best Blastp hit %3D gb|AAD40809.1|L38959_1 (L38959) histone-like DNA-binding protein [Streptococcus sobrinus]	gene	gene1217	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1489
SPy_1491	SPy1491		SPy_1491	1223006	1223593	-	hypothetical protein	Best Blastp hit %3D sp|P54179|YPMS_BACSU HYPOTHETICAL 21.1 KD PROTEIN IN ILVA 3'REGION >gi|7474681|pir||B69939 conserved hypothetical protein ypmS - Bacillus subtilis >gi|1256649|gb|AAA96643.1| (L77246) putative [Bacillus subtilis] >gi|2634593|emb|CAB14091.1| (Z99115) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1218	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1491
SPy_1492	SPy1492		SPy_1492	1223571	1224431	-	hypothetical protein	Best Blastp hit %3D sp|P40766|YPMR_BACSU HYPOTHETICAL 28.9 KD PROTEIN IN ILVA 3'REGION >gi|7474680|pir||A69939 conserved hypothetical protein ypmR - Bacillus subtilis >gi|1256648|gb|AAA96642.1| (L77246) putative [Bacillus subtilis] >gi|2634594|emb|CAB14092.1| (Z99115) alternate gene name: yzjA~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1219	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1492
SPy_1493	SPy1493		SPy_1493	1224406	1225245	-	hypothetical protein	Best Blastp hit %3D emb|CAB66247.1| (AL136518) hypothetical protein SCC123.07c. [Streptomyces coelicolor A3(2)]	gene	gene1220	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1493
SPy_1494	SPy1494		SPy_1494	1225473	1226414	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1221	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1494
SPy_1495	SPy1495	recN	recN	1226586	1228247	-	putative DNA repair and genetic recombination protein	Best Blastp hit %3D sp|P17894|RECN_BACSU DNA REPAIR PROTEIN RECN (RECOMBINATION PROTEIN N) >gi|98443|pir||B35128 DNA repair and genetic recombination protein recN - Bacillus subtilis >gi|143402|gb|AAA22691.1| (M30297) recombination protein (ttg start codon) [Bacillus subtilis] >gi|1303923|dbj|BAA12579.1| (D84432) RecN [Bacillus subtilis] >gi|2634858|emb|CAB14355.1| (Z99116) recN [Bacillus subtilis]	gene	gene1222	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1495
SPy_1496	SPy1496		SPy_1496	1228269	1228739	-	putative repressor protein	Best Blastp hit %3D sp|O31408|ARGR_BACST ARGININE REPRESSOR >gi|2369706|emb|CAA70737.1| (Y09546) arginine repressor [Bacillus stearothermophilus]	gene	gene1223	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1496
SPy_1497	SPy1497	hlyA1	hlyA1	1228726	1229553	-	putative hemolysin	Best Blastp hit %3D sp|P19672|YQXC_BACSU HYPOTHETICAL 29.7 KD PROTEIN IN FOLD-AHRC INTERGENIC REGION >gi|7447260|pir||G69967 hemolysin homolog yqxC - Bacillus subtilis >gi|1303921|dbj|BAA12577.1| (D84432) YqiF [Bacillus subtilis] >gi|2634860|emb|CAB14357.1| (Z99116) alternate gene name: yqiF~similar to hemolysin-like [Bacillus subtilis]	gene	gene1224	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1497
SPy_1498	SPy1498	fps	fps	1229546	1230418	-	putative geranyltranstransferase (farnesyl diphosphate synthase)	Best Blastp hit %3D sp|Q08291|ISPA_BACST GERANYLTRANSTRANSFERASE (FARNESYL-DIPHOSPHATE SYNTHASE) (FPP SYNTHASE) >gi|421467|pir||JX0257 geranyltranstransferase (EC 2.5.1.10) - Bacillus stearothermophilus >gi|391610|dbj|BAA02551.1| (D13293) farnesyl diphosphate synthase [Bacillus stearothermophilus]	gene	gene1225	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1498
SPy_1499	SPy1499	xseB	xseB	1230418	1230633	-	exodeoxyribonuclease VII (small subunit)	Best Blastp hit %3D sp|P22938|EX7S_ECOLI EXODEOXYRIBONUCLEASE VII SMALL SUBUNIT (EXONUCLEASE VII SMALL SUBUNIT) >gi|78539|pir||JQ0664 exodeoxyribonuclease VII (EC 3.1.11.6) small chain - Escherichia coli >gi|216583|dbj|BAA00598.1| (D00694) ORF1 [Escherichia coli] >gi|1773106|gb|AAB40178.1| (U82664) exodeoxyribonuclease small subunit [Escherichia coli] >gi|1786624|gb|AAC73525.1| (AE000148) exonuclease VII%2C small subunit [Escherichia coli]	gene	gene1226	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1499
SPy_1500	SPy1500	xseA	xseA	1230611	1231951	-	putative exodeoxyribonuclease VII (large subunit)	Best Blastp hit %3D dbj|BAB06502.1| (AP001516) exodeoxyribonuclease VII (large subunit) [Bacillus halodurans]	gene	gene1227	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1500
SPy_1502	SPy1502	folD	folD	1232104	1232958	-	putative bifunctional methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase	Best Blastp hit %3D sp|P54382|FOLD_BACSU FOLD BIFUNCTIONAL PROTEIN [INCLUDES: METHYLENETETRAHYDROFOLATE DEHYDROGENASE%3B METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE ] >gi|7431816|pir||E69626 methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) - Bacillus subtilis >gi|1303916|dbj|BAA12572.1| (D84432) YqiA [Bacillus subtilis] >gi|2634865|emb|CAB14362.1| (Z99116) methylenetetrahydrofolate dehydrogenase [Bacillus subtilis]	gene	gene1228	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1502
SPy_1503	SPy1503		SPy_1503	1233166	1234860	-	putative phosphomannomutase	Best Blastp hit %3D dbj|BAB04825.1| (AP001510) phosphomannomutase [Bacillus halodurans]	gene	gene1229	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1503
SPy_1505	SPy1505	phr	phr	1235038	1236447	-	putative deoxyribodipyrimidine photolyase	Best Blastp hit %3D sp|Q04449|PHR_BACFI DEOXYRIBODIPYRIMIDINE PHOTOLYASE (DNA PHOTOLYASE) (PHOTOREACTIVATING ENZYME) >gi|2126786|pir||I39818 deoxyribodipyrimidine photo-lyase (EC 4.1.99.3) - Bacillus firmus (fragment) >gi|142783|gb|AAA22361.1| (M94110) DNA photolyase [Bacillus firmus]	gene	gene1230	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1505
SPy_1506	SPy1506		SPy_1506	1236596	1237330	-	putative amino acid ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB05182.1| (AP001512) ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1231	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1506
SPy_1507	SPy1507		SPy_1507	1237330	1238016	-	putative amino acid ABC transporter (permease protein)	Best Blastp hit %3D pir||S77250 hypothetical protein - Synechocystis sp. (strain PCC 6803) >gi|1652664|dbj|BAA17584.1| (D90907) glutamine-binding periplasmic protein [Synechocystis sp.]	gene	gene1232	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1507
SPy_1508	SPy1508		SPy_1508	1238143	1238373	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1233	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1508
SPy_1509	SPy1509	clpE	clpE	1238671	1240953	+	putative ATP-dependent protease	Best Blastp hit %3D gb|AAD01782.1| (AF023421) ClpE [Lactococcus lactis]	gene	gene1234	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1509
SPy_1510	SPy1510	mutT	mutT	1241081	1241536	+	putative mutator protein	Best Blastp hit %3D pir||G64935 hypothetical protein b1759 - Escherichia coli (strain K-12) >gi|1742868|dbj|BAA15549.1| (D90819) Mutator MutT protein (7%2C8-dihydro-8-oxoguanine-triphosphatase) (8-oxo-dgtpase) (EC 3.6.1.-) (DGTP pyrophosphohydrolase). [Escherichia coli] >gi|1788056|gb|AAC74829.1| (AE000270) orf%2C hypothetical protein [Escherichia coli]	gene	gene1235	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1510
SPy_1511	SPy1511		SPy_1511	1241587	1241889	+	hypothetical protein	Best Blastp hit %3D pir||T34105 hypothetical protein C17G10.8 - Caenorhabditis elegans >gi|2731377|gb|AAB93456.1| (U28739) similar to alcohol dehydrogenase/ribitol dehydrogenase [Caenorhabditis elegans]	gene	gene1236	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1511
SPy_1513	SPy1513	ileS	ileS	1242154	1244955	-	putative isoleucyl-tRNA synthetase	Best Blastp hit %3D sp|Q45477|SYI_BACSU ISOLEUCYL-TRNA SYNTHETASE (ISOLEUCINE-TRNA LIGASE) (ILERS) >gi|7437553|pir||H69643 isoleucine-tRNA ligase (EC 6.1.1.5) ileS - Bacillus subtilis >gi|2633916|emb|CAB13417.1| (Z99112) isoleucyl-tRNA synthetase [Bacillus subtilis]	gene	gene1237	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1513
SPy_1514	SPy1514	divIVAS	divIVAS	1245228	1245986	-	cell-division initiation protein (septum placement)	Best Blastp hit %3D dbj|BAB06265.1| (AP001515) cell-division initiation protein (septum placement) [Bacillus halodurans]	gene	gene1238	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1514
SPy_1515	SPy1515		SPy_1515	1245996	1246787	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06266.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1239	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1515
SPy_1516	SPy1516		SPy_1516	1246787	1247041	-	hypothetical protein	Best Blastp hit %3D emb|CAA75619.1| (Y15422) hypothetical protein [Lactococcus lactis subsp. cremoris]	gene	gene1240	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1516
SPy_1518	SPy1518		SPy_1518	1247046	1247702	-	hypothetical protein	Best Blastp hit %3D emb|CAA75618.1| (Y15422) hypothetical protein [Lactococcus lactis subsp. cremoris]	gene	gene1241	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1518
SPy_1519	SPy1519		SPy_1519	1247714	1248385	-	hypothetical protein	Best Blastp hit %3D emb|CAA75617.1| (Y15422) hypothetical protein [Lactococcus lactis subsp. cremoris]	gene	gene1242	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1519
SPy_1520	SPy1520	ftsZ	ftsZ	1248388	1249707	-	putative cell division protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAA75616.1| (Y15422) cell division protein FtsZ [Lactococcus lactis subsp. cremoris]	gene	gene1243	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1520
SPy_1521	SPy1521	ftsA	ftsA	1249731	1251095	-	cell division protein	Best Blastp hit %3D sp|O07672|FTSA_ENTHR CELL DIVISION PROTEIN FTSA >gi|2222676|emb|CAA74237.1| (Y13922) ftsA [Enterococcus hirae]	gene	gene1244	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1521
SPy_1523	SPy1523	divIB	divIB	1251307	1252455	-	cell division protein	Best Blastp hit %3D gb|AAC95451.1| (AF068902) cell division protein DivIB [Streptococcus pneumoniae]	gene	gene1245	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1523
SPy_1524	SPy1524	murG	murG	1252456	1253538	-	putative undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase	Best Blastp hit %3D sp|Q9ZHA9|MURG_STRPN UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE (UNDECAPRENYL-PP-MURNAC-PENTAPEPTIDE-UDPGLCNAC GLCNAC TRANSFERASE) >gi|4009481|gb|AAC95450.1| (AF068902) undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [Streptococcus pneumoniae]	gene	gene1246	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1524
SPy_1525	SPy1525	murD	murD	1253538	1254896	-	putative UDP-N-acetylmuramoylalanine-D-glutamate ligase	Best Blastp hit %3D dbj|BAB16028.1| (AB030645) MurD [Streptococcus pyogenes]	gene	gene1247	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1525
SPy_1526	SPy1526		SPy_1526	1255280	1255531	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1248	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1526
SPy_1527	SPy1527		SPy_1527	1255653	1257494	-	putative GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A)	Best Blastp hit %3D dbj|BAB06351.1| (AP001516) GTP-binding protein TypA/BipA (tyrosine phosphorylated protein A) [Bacillus halodurans]	gene	gene1249	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1527
SPy_1528	SPy1528		SPy_1528	1257677	1258066	-	hypothetical protein	Best Blastp hit %3D sp|P54510|YQHL_BACSU HYPOTHETICAL 14.6 KD PROTEIN IN GCVT-SPOIIIAA INTERGENIC REGION >gi|7429010|pir||C69959 glpE protein homolog yqhL - Bacillus subtilis >gi|1303893|dbj|BAA12549.1| (D84432) YqhL [Bacillus subtilis] >gi|2634888|emb|CAB14385.1| (Z99116) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1250	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1528
SPy_1529	SPy1529	glcK	glcK	1258076	1259047	-	glucose kinase	Best Blastp hit %3D pir||T44787 glucokinase (EC 2.7.1.2) [imported] - Bacillus megaterium >gi|2274867|emb|CAA03848.1| (AJ000005) glucose kinase [Bacillus megaterium]	gene	gene1251	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1529
SPy_1530	SPy1530		SPy_1530	1259052	1259255	-	hypothetical protein	Best Blastp hit %3D emb|CAA03847.1| (AJ000005) orf1 [Bacillus megaterium]	gene	gene1252	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1530
SPy_1531	SPy1531	dpr	dpr	1259397	1259924	-	putative peroxide resistance protein	Best Blastp hit %3D gb|AAG33871.1|AF319974_1 (AF319974) Dpr [Streptococcus suis]	gene	gene1253	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1531
SPy_1532	SPy1532		SPy_1532	1260152	1260778	+	hypothetical protein	Best Blastp hit %3D dbj|BAA96471.1| (AB036428) type IV prepilin peptidase homologue [Streptococcus mutans]	gene	gene1254	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1532
SPy_1533	SPy1533		SPy_1533	1260860	1261939	-	hypothetical protein	Best Blastp hit %3D sp|O34617|YLON_BACSU HYPOTHETICAL 41.6 KDA PROTEIN IN FMT-SPOVM INTERGENIC REGION >gi|7448849|pir||F69878 conserved hypothetical protein yloN - Bacillus subtilis >gi|2337804|emb|CAA74265.1| (Y13937) YloN protein [Bacillus subtilis] >gi|2633947|emb|CAB13448.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1255	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1533
SPy_1534	SPy1534		SPy_1534	1261943	1262587	-	hypothetical protein	Best Blastp hit %3D pir||F70023 hypothetical protein yutD - Bacillus subtilis >gi|2635728|emb|CAB15221.1| (Z99120) yutD [Bacillus subtilis]	gene	gene1256	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1534
SPy_1535	SPy1535		SPy_1535	1263011	1263988	-	putative ribose transport operon repressor	Best Blastp hit %3D pir||I40462 repressor of ribose transport operon - Bacillus subtilis >gi|580917|emb|CAA81048.1| (Z25798) repressor of ribose transport operon [Bacillus subtilis]	gene	gene1257	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1535
SPy_1536	SPy1536		SPy_1536	1264402	1265439	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06305.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene1258	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1536
SPy_1537	SPy1537	kdtB	kdtB	1265426	1265917	-	putative 3-deoxy-D-manno-octulosonic-acid transferase	Best Blastp hit %3D pir||G81347 3-deoxy-D-manno-octulosonic-acid transferase Cj0767c [imported] - Campylobacter jejuni (strain NCTC 11168) >gi|6968213|emb|CAB73032.1| (AL139076) 3-deoxy-D-manno-octulosonic-acid transferase [Campylobacter jejuni]	gene	gene1259	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1537
SPy_1538	SPy1538		SPy_1538	1265907	1266446	-	hypothetical protein	Best Blastp hit %3D pir||E69874 conserved hypothetical protein ylbH - Bacillus subtilis >gi|2340004|emb|CAB11354.1| (Z98682) YlbH protein [Bacillus subtilis] >gi|2633872|emb|CAB13374.1| (Z99111) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1260	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1538
SPy_1539	SPy1539	asnA	asnA	1266569	1267561	-	putative asparagine synthetase A	Best Blastp hit %3D pir||H71309 probable asparagine synthetase (asnA) - syphilis spirochete >gi|3322850|gb|AAC26560.1| (AE001231) asparagine synthetase (asnA) [Treponema pallidum]	gene	gene1261	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1539
SPy_1541	SPy1541	arcC	arcC	1267874	1268824	-	putative carbamate kinase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|O53090|ARCC_LACSK CARBAMATE KINASE >gi|11260628|pir||T46743 carbamate kinase (EC 2.7.2.2) [validated] - Lactobacillus sakei >gi|2764613|emb|CAA04684.1| (AJ001330) carbamate kinase [Lactobacillus sakei]	gene	gene1262	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1541
SPy_1542	SPy1542		SPy_1542	1268844	1270175	-	putative Xaa-His dipeptidase	Best Blastp hit %3D pir||B69994 Xaa-His dipeptidase homolog ytjP - Bacillus subtilis >gi|2293201|gb|AAC00279.1| (AF008220) putative peptidase [Bacillus subtilis] >gi|2635482|emb|CAB14976.1| (Z99119) similar to Xaa-His dipeptidase [Bacillus subtilis]	gene	gene1263	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1542
SPy_1543	SPy1543		SPy_1543	1270192	1271685	-	hypothetical protein	Best Blastp hit %3D pir||B70205 conserved hypothetical integral membrane protein BB0843 - Lyme disease spirochete >gi|2688787|gb|AAC67189.1| (AE001183) conserved hypothetical integral membrane protein [Borrelia burgdorferi]	gene	gene1264	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1543
SPy_1544	SPy1544	arcB	arcB	1271855	1272868	-	putative ornithine transcarbamylase	Best Blastp hit %3D emb|CAB93580.1| (AJ250129) ornithine transcarbamylase [Lactococcus lactis]	gene	gene1265	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1544
SPy_1546	SPy1546		SPy_1546	1272908	1273336	-	hypothetical protein	Best Blastp hit %3D sp|P52080|YAT3_STAAU HYPOTHETICAL 16.6 KDA PROTEIN IN ATL 5'REGION (ORF3) >gi|725453|dbj|BAA04184.1| (D17366) ORF3 [Staphylococcus aureus] >gi|765072|gb|AAA99981.1| (L41499) ORF3 [Staphylococcus aureus]	gene	gene1266	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1546
SPy_1547	SPy1547	sagP	sagP	1273436	1274671	-	streptococcal antitumor protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D prf||1313186A antitumor glycoprotein [Streptococcus pyogenes]	gene	gene1267	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1547
SPy_1548	SPy1548		SPy_1548	1274945	1275625	-	hypothetical protein	Best Blastp hit %3D emb|CAB95946.1| (Y17554) Crp/Fnr family protein [Bacillus licheniformis]	gene	gene1268	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1548
SPy_1549	SPy1549	ahrC.2	ahrC.2	1275767	1276240	+	putative arginine repressor	Best Blastp hit %3D sp|O86130|ARGR_BACLI ARGININE REPRESSOR >gi|3687414|emb|CAA76776.1| (Y17553) arginine repressor [Bacillus licheniformis]	gene	gene1269	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1549
SPy_1551	SPy1551		SPy_1551	1276406	1277122	-	conserved protein - function unknown	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||C72564 hypothetical protein APE1797 - Aeropyrum pernix (strain K1) >gi|5105487|dbj|BAA80800.1| (AP000062) 229aa long hypothetical protein [Aeropyrum pernix]	gene	gene1270	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1551
SPy_1552	SPy1552		SPy_1552	1277136	1278215	-	hypothetical protein	Best Blastp hit %3D pir||A75277 conserved hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6460219|gb|AAF11947.1|AE002071_1 (AE002071) conserved hypothetical protein [Deinococcus radiodurans]	gene	gene1271	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1552
SPy_1553	SPy1553		SPy_1553	1278288	1280021	-	putative two-component sensor kinase	Best Blastp hit %3D	gene	gene1272	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1553
SPy_1556	SPy1556		SPy_1556	1280018	1280758	-	putative two-component response regulator	Best Blastp hit %3D dbj|BAB07398.1| (AP001519) two-component response regulator [Bacillus halodurans]	gene	gene1273	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1556
SPy_1557	SPy1557	msrA	msrA	1280846	1281952	-	putative peptide methionine sulfoxide reductase	Best Blastp hit %3D gb|AAF36477.1|AF128264_2 (AF128264) methionine sulfoxide reductase [Streptococcus gordonii]	gene	gene1274	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1557
SPy_1558	SPy1558		SPy_1558	1281995	1282618	-	hypothetical protein	Best Blastp hit %3D emb|CAB83597.1| (AL162752) peptide methionine sulfoxide reductase [Neisseria meningitidis]	gene	gene1275	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1558
SPy_1559	SPy1559	ccdA	ccdA	1282631	1283341	-	putative cytochrome C-type biogenesis protein	Best Blastp hit %3D gb|AAG29835.1|AF308446_2 (AF308446) cytochrome c biogenesis protein CcdA [Paracoccus pantotrophus]	gene	gene1276	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1559
SPy_1561	SPy1561		SPy_1561	1283879	1284172	-	hypothetical protein	Best Blastp hit %3D pir||A72210 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4982376|gb|AAD36859.1|AE001817_6 (AE001817) conserved hypothetical protein [Thermotoga maritima]	gene	gene1277	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1561
SPy_1562	SPy1562		SPy_1562	1284183	1285208	-	hypothetical protein	Best Blastp hit %3D pir||E69484 conserved hypothetical protein AF1878 - Archaeoglobus fulgidus >gi|2648666|gb|AAB89374.1| (AE000973) conserved hypothetical protein [Archaeoglobus fulgidus]	gene	gene1278	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1562
SPy_1563	SPy1563		SPy_1563	1285205	1285879	-	hypothetical protein	Best Blastp hit %3D pir||F72596 hypothetical protein APE1239 - Aeropyrum pernix (strain K1) >gi|5104914|dbj|BAA80228.1| (AP000061) 221aa long hypothetical protein [Aeropyrum pernix]	gene	gene1279	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1563
SPy_1564	SPy1564		SPy_1564	1285881	1286729	-	hypothetical protein	Best Blastp hit %3D pir||F72210 hypothetical protein TM1801 - Thermotoga maritima (strain MSB8) >gi|4982381|gb|AAD36864.1|AE001817_11 (AE001817) hypothetical protein [Thermotoga maritima]	gene	gene1280	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1564
SPy_1565	SPy1565		SPy_1565	1286734	1288629	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1281	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1565
SPy_1566	SPy1566		SPy_1566	1288629	1289357	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1282	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1566
SPy_1567	SPy1567		SPy_1567	1289490	1291898	-	hypothetical protein	Best Blastp hit %3D pir||D72210 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4982379|gb|AAD36862.1|AE001817_9 (AE001817) conserved hypothetical protein [Thermotoga maritima]	gene	gene1283	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1567
SPy_1568	SPy1568	valS	valS	1292052	1294700	-	putative valine-tRNA ligase	Best Blastp hit %3D pir||SYBSVS valine-tRNA ligase (EC 6.1.1.9) - Bacillus stearothermophilus	gene	gene1284	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1568
SPy_1569	SPy1569		SPy_1569	1294702	1295265	-	hypothetical protein	Best Blastp hit %3D gi|10835037 tetratricopeptide repeat domain 3%3B tetratricopeptide repeat protein 3 (TPR repeat protein D) [Homo sapiens] >gi|1632764|dbj|BAA12302.1| (D84295) possible protein TPRDII [Homo sapiens]	gene	gene1285	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1569
SPy_1570	SPy1570		SPy_1570	1295262	1295441	-	hypothetical protein	Best Blastp hit %3D gb|AAG19022.1| (AE005002) probable acetyltransferase%3B Hat1 [Halobacterium sp. NRC-1]	gene	gene1286	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1570
SPy_1571	SPy1571		SPy_1571	1295866	1296261	-	hypothetical protein	Best Blastp hit %3D gi|6320942 RecA homolog%3B Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1)%2C and interacts with Rad52p and Rad55p%3B human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer%3B Ra> >gi|131783|sp|P25454|RA51_YEAST DNA REPAIR PROTEIN RAD51 >gi|322955|pir||A44348 RAD51 protein - yeast (Saccharomyces cerevisiae) >gi|4275|emb|CAA45563.1| (X64270) similarities to procaryotic RecA [Saccharomyces cerevisiae] >gi|172339|gb|AAA34948.1| (M88470) RAD51 protein [Saccharomyces cerevisiae] >gi|218469|dbj|BAA00913.1| (D10023) Rad51 protein [Saccharomyces cerevisiae] >gi|603333|gb|AAB64650.1| (U18839) Rad51p: RecA-like protein [Saccharomyces cerevisiae]	gene	gene1287	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1571
SPy_1572	SPy1572		SPy_1572	1296279	1296533	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1288	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1572
SPy_1574	SPy1574		SPy_1574	1296963	1298096	+	putative transposase - IS1548	Best Blastp hit %3D emb|CAA74641.1| (Y14270) putative transposase [Streptococcus agalactiae]	gene	gene1290	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1574
SPy_1575	SPy1575		SPy_1575	1298101	1298286	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1291	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1575
SPy_1576	SPy1576		SPy_1576	1298338	1299090	+	putative chorismate mutase	Best Blastp hit %3D sp|P39912|AROG_BACSU AROA(G) PROTEIN [INCLUDES: PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE (PHOSPHO-2-KETO-3-DEOXYHEPTONATE ALDOLASE) (DAHP SYNTHETASE) (3-DEOXY-D-ARABINO-HEPTULOSONATE 7-PHOSPHATE SYNTHASE)%3B CHORISMATE MUTASE ] >gi|98429|pir||S21418 2-dehydro-3-deoxyphosphoheptonate aldolase (EC 4.1.2.15) - Bacillus subtilis >gi|39813|emb|CAA46760.1| (X65945) phospho-2-dehydro-3-deoxyheptonate aldolase [Bacillus subtilis] >gi|2293220|gb|AAC00298.1| (AF008220) DAPH synthase-chorismate mutase [Bacillus subtilis] >gi|2635459|emb|CAB14953.1| (Z99119) 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase [Bacillus subtilis]	gene	gene1292	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1576
SPy_1577	SPy1577	aroB	aroB	1299146	1300219	+	3-dehydroquinate synthase	Best Blastp hit %3D sp|P73997|AROB_SYNY3 3-DEHYDROQUINATE SYNTHASE >gi|7428410|pir||S75507 3-dehydroquinate synthase - Synechocystis sp. (strain PCC 6803) >gi|1653152|dbj|BAA18068.1| (D90911) 3-dehydroquinate synthase [Synechocystis sp.]	gene	gene1293	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1577
SPy_1580	SPy1580		SPy_1580	1300654	1300959	-	putative acetate kinase	Best Blastp hit %3D pir||D69060 hypothetical protein MTH1452 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622565|gb|AAB85927.1| (AE000906) unknown [Methanobacterium thermoautotrophicum]	gene	gene1294	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1580
SPy_1581	SPy1581		SPy_1581	1300961	1301299	-	hypothetical protein	Best Blastp hit %3D pir||D69060 hypothetical protein MTH1452 - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2622565|gb|AAB85927.1| (AE000906) unknown [Methanobacterium thermoautotrophicum]	gene	gene1295	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1581
SPy_1582	SPy1582		SPy_1582	1301352	1302107	-	hypothetical protein	Best Blastp hit %3D sp|Q57060|Y095_HAEIN HYPOTHETICAL PROTEIN HI0095 >gi|1075323|pir||B64048 hypothetical protein HI0095 - Haemophilus influenzae (strain Rd KW20) >gi|1573047|gb|AAC21772.1| (U32695) conserved hypothetical protein [Haemophilus influenzae Rd]	gene	gene1296	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1582
SPy_1584	SPy1584	aroE	aroE	1302342	1303220	-	putative shikimate 5-dehydrogenase	Best Blastp hit %3D sp|Q58484|AROE_METJA SHIKIMATE 5-DEHYDROGENASE >gi|2129280|pir||C64435 shikimate 5-dehydrogenase (EC 1.1.1.25) - Methanococcus jannaschii >gi|1591730|gb|AAB99086.1| (U67551) shikimate 5-dehydrogenase (aroE) [Methanococcus jannaschii]	gene	gene1297	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1584
SPy_1586	SPy1586		SPy_1586	1303358	1306864	-	putative beta-galactosidase	Best Blastp hit %3D gb|AAF97242.1|AF282987_1 (AF282987) beta-galactosidase precursor [Streptococcus pneumoniae]	gene	gene1298	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1586
SPy_1587	SPy1587		SPy_1587	1306794	1308278	-	putative two-component sensor response regulator	Best Blastp hit %3D dbj|BAB04512.1| (AP001509) two-component sensor response regulator [Bacillus halodurans]	gene	gene1299	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1587
SPy_1588	SPy1588		SPy_1588	1308278	1310002	-	putative two-component sensor histidine kinase	Best Blastp hit %3D dbj|BAB04511.1| (AP001509) two-component sensor histidine kinase [Bacillus halodurans]	gene	gene1300	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1588
SPy_1589	SPy1589		SPy_1589	1309992	1310597	-	hypothetical protein	Best Blastp hit %3D pir||C69796 conserved hypothetical protein yesL - Bacillus subtilis >gi|2633007|emb|CAB12513.1| (Z99107) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1301	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1589
SPy_1592	SPy1592		SPy_1592	1310903	1312348	-	putative ABC transporter substrate binding lipoprotein	Best Blastp hit %3D sp|P37966|LPLA_BACSU LIPOPROTEIN LPLA PRECURSOR >gi|2127131|pir||I39876 lipoprotein lplA - Bacillus subtilis >gi|431272|gb|AAC36913.1| (L03376) lysis protein [Bacillus subtilis] >gi|2633023|emb|CAB12529.1| (Z99107) lipoprotein [Bacillus subtilis]	gene	gene1302	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1592
SPy_1593	SPy1593		SPy_1593	1312429	1313355	-	putative sugar-binding transport protein	Best Blastp hit %3D emb|CAB01403.1| (Z77855) sugar-binding transport protein [Anaerocellum thermophilum]	gene	gene1303	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1593
SPy_1595	SPy1595		SPy_1595	1313365	1314315	-	putative sugar-binding transport protein	Best Blastp hit %3D emb|CAB01402.1| (Z77855) sugar-binding transport protein [Anaerocellum thermophilum]	gene	gene1304	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1595
SPy_1596	SPy1596		SPy_1596	1314466	1315389	+	putative transcriptional regulator	Best Blastp hit %3D dbj|BAB04505.1| (AP001509) transcriptional regulator [Bacillus halodurans]	gene	gene1305	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1596
SPy_1599	SPy1599		SPy_1599	1316000	1317442	-	putative beta-glucosidase	Best Blastp hit %3D pir||D69785 beta-glucosidase homolog ydhP - Bacillus subtilis >gi|1945100|dbj|BAA19708.1| (D88802) C. thermocellum beta-glucosidase%3B P26208 (985) [Bacillus subtilis] >gi|2632897|emb|CAB12403.1| (Z99107) similar to beta-glucosidase [Bacillus subtilis]	gene	gene1306	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1599
SPy_1600	SPy1600		SPy_1600	1317466	1319160	-	putative hyaluronidase	Best Blastp hit %3D gi|11024698 meningioma expressed antigen 5 (hyaluronidase)%3B hyaluronidase in meningioma [Homo sapiens] >gi|10835356|gb|AAD05385.2| (AF036144) meningioma-expressed antigen 5 [Homo sapiens]	gene	gene1307	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1600
SPy_1602	SPy1602		SPy_1602	1319211	1320251	-	putative transcription regulator	Best Blastp hit %3D dbj|BAB05594.1| (AP001513) transcriptional repressor of the arabinose operon [Bacillus halodurans]	gene	gene1308	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1602
SPy_1603	SPy1603		SPy_1603	1320357	1321670	+	hypothetical protein	Best Blastp hit %3D dbj|BAB04509.1| (AP001509) unknown conserved protein in others [Bacillus halodurans]	gene	gene1309	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1603
SPy_1604	SPy1604		SPy_1604	1321685	1324390	+	hypothetical protein	Best Blastp hit %3D dbj|BAB04508.1| (AP001509) unknown conserved protein in others (divided) [Bacillus halodurans]	gene	gene1310	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1604
SPy_1605	SPy1605		SPy_1605	1324491	1325846	-	putative two-component responsible histidine kinase	Best Blastp hit %3D emb|CAC10171.1| (AJ278301) histidine kinase [Streptococcus pneumoniae]	gene	gene1311	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1605
SPy_1606	SPy1606		SPy_1606	1326511	1327866	-	putative RNA methyltransferase	Best Blastp hit %3D dbj|BAB04616.1| (AP001510) RNA methyltransferase [Bacillus halodurans]	gene	gene1312	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1606
SPy_1607	SPy1607		SPy_1607	1327981	1328757	+	hypothetical protein	Best Blastp hit %3D pir||H69800 hypothetical protein yfhG - Bacillus subtilis >gi|2633176|emb|CAB12681.1| (Z99108) yfhG [Bacillus subtilis] >gi|2804537|dbj|BAA24473.1| (D85082) YfhG [Bacillus subtilis]	gene	gene1313	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1607
SPy_1608	SPy1608		SPy_1608	1328837	1329370	+	hypothetical protein	Best Blastp hit %3D dbj|BAB04659.1| (AP001510) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1314	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1608
SPy_1610	SPy1610		SPy_1610	1329740	1330018	+	hypothetical protein	Best Blastp hit %3D gb|AAF61313.1| (U96166) unknown [Streptococcus cristatus]	gene	gene1315	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1610
SPy_1613	SPy1613		SPy_1613	1337063	1337611	-	conserved protein - function unknown	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P28368|YVYD_BACSU HYPOTHETICAL 22.0 KD PROTEIN IN FLIT-SECA INTERGENIC REGION >gi|2127111|pir||I40400 ribosomal protein S30AE family homolog yvyD - Bacillus subtilis >gi|499384|emb|CAA83251.1| (Z31376) orf189 [Bacillus subtilis] >gi|1762348|gb|AAC44956.1| (U56901) sigma-54 modulator homolog [Bacillus subtilis] >gi|2636057|emb|CAB15548.1| (Z99122) alternate gene name: yviI~similar to ribosomal protein S30AE family [Bacillus subtilis]	gene	gene1326	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1613
SPy_1615	SPy1615	comFC	comFC	1337691	1338356	-	putative late competence protein	Best Blastp hit %3D gb|AAB59015.1| (L14437) in Z18629%2C ORFX is called comForf3%3B ORFX%3B putative [Bacillus subtilis]	gene	gene1327	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1615
SPy_1616	SPy1616	comFA	comFA	1338328	1339653	-	putative late competence protein required for DNA uptake	Best Blastp hit %3D dbj|BAB07345.1| (AP001519) late competence protein [Bacillus halodurans]	gene	gene1328	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1616
SPy_1617	SPy1617		SPy_1617	1339709	1340341	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07349.1| (AP001519) unknown conserved protein [Bacillus halodurans]	gene	gene1329	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1617
SPy_1618	SPy1618	cysM	cysM	1340469	1341410	+	putative O-acetylserine lyase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAA88310.1| (AB028865) O-acetylserine lyase [Streptococcus suis]	gene	gene1330	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1618
SPy_1619	SPy1619		SPy_1619	1341428	1341805	-	putative polyribonucleotide nucleotidyltransferase (general stress protein)	Best Blastp hit %3D sp|P80870|GS13_BACSU GENERAL STRESS PROTEIN 13 (GSP13) >gi|7447105|pir||H70010 polyribonucleotide nucleotidyltransferase homolog yugI - Bacillus subtilis >gi|1934792|emb|CAB07921.1| (Z93934) unknown [Bacillus subtilis] >gi|2635635|emb|CAB15128.1| (Z99120) similar to polyribonucleotide nucleotidyltransferase [Bacillus subtilis]	gene	gene1331	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1619
SPy_1620	SPy1620		SPy_1620	1341805	1343205	-		This gene appears tp be the results of a mutations leading to the fusion of 2 adjacent genes%2C a conserved hypothetical protein and peptidyl-prolyl cis-trans isomerase. There is no evidence that this fusion is the result of a sequencing artifact.%3B Best Blastp hit %3D gi|12723823|gb|AAK04990.1|AE006323_5 (AE006323) conserved hypothetical protein [Lactococcus lactis subsp. lactis]%3B gi|12723824|gb|AAK04991.1|AE006323_6 (AE006323) peptidyl-prolyl cis-trans isomerase [Lactococcus lactis subsp. lactis]	gene	gene1332	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1620
SPy_1621	SPy1621		SPy_1621	1343242	1343883	-	putative two-component response regulator	Best Blastp hit %3D dbj|BAB04919.1| (AP001511) two-component response regulator [Bacillus halodurans]	gene	gene1333	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1621
SPy_1622	SPy1622		SPy_1622	1343876	1344880	-	putative two-component sensor histidine kinase	Best Blastp hit %3D dbj|BAB04918.1| (AP001511) two-component sensor histidine kinase [Bacillus halodurans]	gene	gene1334	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1622
SPy_1623	SPy1623		SPy_1623	1344877	1345620	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04917.1| (AP001511) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1335	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1623
SPy_1625	SPy1625		SPy_1625	1345692	1347590	-	putative protein kinase	Best Blastp hit %3D pir||H69878 probable protein kinase (EC 2.7.1.-) yloP - Bacillus subtilis >gi|2337806|emb|CAA74267.1| (Y13937) putative Pkn2 protein [Bacillus subtilis] >gi|2633949|emb|CAB13450.1| (Z99112) similar to protein kinase [Bacillus subtilis]	gene	gene1336	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1625
SPy_1626	SPy1626	pppL	pppL	1347587	1348327	-	putative phosphoprotein phosphatase	Best Blastp hit %3D pir||G69878 conserved hypothetical protein yloO - Bacillus subtilis >gi|2337805|emb|CAA74266.1| (Y13937) putative Ptc1 protein [Bacillus subtilis] >gi|2633948|emb|CAB13449.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1337	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1626
SPy_1627	SPy1627	sunL	sunL	1348365	1349687	-	putative RNA-binding Sun protein	Best Blastp hit %3D dbj|BAB06226.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1338	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1627
SPy_1628	SPy1628	fmt	fmt	1349677	1350612	-	putative methionyl tRNA formyltransferase	Best Blastp hit %3D emb|CAA71350.1| (Y10304) Met-tRNAi formyl transferase [Bacillus subtilis]	gene	gene1339	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1628
SPy_1629	SPy1629	priA	priA	1350674	1353058	-	putative primosomal replication factor Y	Best Blastp hit %3D dbj|BAB06228.1| (AP001515) primosomal replication factor Y [Bacillus halodurans]	gene	gene1340	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1629
SPy_1630	SPy1630		SPy_1630	1353123	1353437	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06230.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1341	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1630
SPy_1632	SPy1632	gmk	gmk	1353456	1354091	-	putative guanylate kinase	Best Blastp hit %3D dbj|BAB06231.1| (AP001515) guanylate kinase [Bacillus halodurans]	gene	gene1342	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1632
SPy_1633	SPy1633		SPy_1633	1354201	1355808	-	hypothetical protein	Best Blastp hit %3D gb|AAF34762.1|AF228345_1 (AF228345) unknown [Listeria monocytogenes]	gene	gene1343	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1633
SPy_1634	SPy1634		SPy_1634	1355938	1356834	-	putative transcriptional regulator (LysR family)	Best Blastp hit %3D sp|P39592|YWBI_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR YWBI >gi|629031|pir||S39679 transcription regulator homolog ywbI - Bacillus subtilis >gi|413948|emb|CAA51580.1| (X73124) ipa-24d [Bacillus subtilis] >gi|2636366|emb|CAB15857.1| (Z99123) alternate gene name: ipa-24d~similar to transcriptional regulator (LysR family) [Bacillus subtilis]	gene	gene1344	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1634
SPy_1637	SPy1637	atoB	atoB	1357036	1358223	+	putative acetyl-CoA:acetyltransferase	Best Blastp hit %3D pir||T45290 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) [imported] - Clostridium thermosaccharolyticum >gi|1667356|emb|CAB04793.1| (Z82038) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum] >gi|1903332|emb|CAB07500.1| (Z92974) acetyl coenzyme A acetyltransferase (thiolase) [Thermoanaerobacterium thermosaccharolyticum]	gene	gene1345	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1637
SPy_1638	SPy1638	atoD.1	atoD.1	1358247	1358897	+	putative Acetyl-CoA:acetoacetyl-CoA transferase A subunit	Best Blastp hit %3D sp|P76458|ATOD_ECOLI ACETATE COA-TRANSFERASE ALPHA SUBUNIT (ACETYL-COA:ACETOACETATE COA TRANSFERASE) >gi|7434985|pir||C64992 atoD protein - Escherichia coli (strain K-12) >gi|1736876|dbj|BAA16017.1| (D90851) Acetyl-CoA:acetoacetyl-CoA transferase a subunit (EC 2.8.3.-). [Escherichia coli] >gi|1788551|gb|AAC75281.1| (AE000311) acetyl-CoA:acetoacetyl-CoA transferase alpha subunit [Escherichia coli]	gene	gene1346	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1638
SPy_1639	SPy1639	atoA	atoA	1358899	1359558	+	putative Acetyl-CoA:acetoacetyl-CoA transferase b subunit	Best Blastp hit %3D gb|AAD54948.1|AF157306_3 (AF157306) acetoacetate:butyrate/acetate coenzyme A transferase [Clostridium beijerinckii]	gene	gene1347	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1639
SPy_1640	SPy1640		SPy_1640	1359591	1360370	+	putative oxidoreductase	Best Blastp hit %3D sp|P42317|YXJF_BACSU HYPOTHETICAL OXIDOREDUCTASE IN PEPT-KATB INTERGENIC REGION >gi|7431062|pir||D70079 gluconate 5-dehydrogenase homolog yxjF - Bacillus subtilis >gi|666004|dbj|BAA11707.1| (D83026) homologous to many ketoreductases and steroid dehydrogenases%3B hypothetical [Bacillus subtilis] >gi|2636432|emb|CAB15923.1| (Z99123) similar to gluconate 5-dehydrogenase [Bacillus subtilis] >gi|2636443|emb|CAB15933.1| (Z99124) similar to gluconate 5-dehydrogenase [Bacillus subtilis]	gene	gene1348	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1640
SPy_1641	SPy1641		SPy_1641	1360441	1361772	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07616.1| (AP001520) unknown conserved protein [Bacillus halodurans]	gene	gene1349	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1641
SPy_1642	SPy1642	luxS	luxS	1361846	1362328	+	autoinducer-2 production protein	Best Blastp hit %3D gb|AAG28749.1|AF295118_1 (AF295118) LuxS [Streptococcus pyogenes]	gene	gene1350	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1642
SPy_1643	SPy1643		SPy_1643	1362473	1363942	-	hypothetical protein	Best Blastp hit %3D gb|AAA29456.1| (M69161) antigen 332 [Plasmodium falciparum]	gene	gene1351	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1643
SPy_1644	SPy1644		SPy_1644	1363956	1365110	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05490.1| (AP001513) unknown conserved protein [Bacillus halodurans]	gene	gene1352	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1644
SPy_1646	SPy1646		SPy_1646	1365555	1365881	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05488.1| (AP001513) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1353	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1646
SPy_1647	SPy1647		SPy_1647	1366003	1366518	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05487.1| (AP001513) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1354	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1647
SPy_1648	SPy1648	recU	recU	1366599	1367198	+	putative recombination protein U	Best Blastp hit %3D sp|Q00579|RECU_STROR RECOMBINATION PROTEIN U HOMOLOG >gi|153770|gb|AAA26957.1| (M90528) ORF [Streptococcus oralis]	gene	gene1355	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1648
SPy_1649	SPy1649	pbp1A	pbp1A	1367185	1369350	+	putative penicillin-binding protein 1a	Best Blastp hit %3D emb|CAA88917.1| (Z49094) penicillin-binding protein 1a [Streptococcus pneumoniae] >gi|984231|emb|CAA88918.1| (Z49095) penicillin-binding protein 1a [Streptococcus pneumoniae]	gene	gene1356	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1649
SPy_1651	SPy1651	pepC	pepC	1369817	1371154	-	putative cysteine aminopeptidase C	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|Q04723|PEPC_LACLC AMINOPEPTIDASE C >gi|477846|pir||B48957 cysteine aminopeptidase PepC - Lactococcus lactis >gi|149364|gb|AAA74514.1| (M86245) cysteine aminopeptidase [Lactococcus lactis]	gene	gene1357	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1651
SPy_1652	SPy1652	nadE	nadE	1371339	1372163	-	putative NAD+ synthase	Best Blastp hit %3D pir||A26928 nitrogen-regulatory protein - Escherichia coli >gi|146974|gb|AAA79852.1| (M15328) NH3-dependent NAD synthetase [Escherichia coli]	gene	gene1358	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1652
SPy_1653	SPy1653		SPy_1653	1372165	1373619	-	putative nicotinate phosphoribosyltransferase	Best Blastp hit %3D pir||B70179 conserved hypothetical protein BB0635 - Lyme disease spirochete >gi|2688569|gb|AAB91532.1| (AE001165) conserved hypothetical protein [Borrelia burgdorferi]	gene	gene1359	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1653
SPy_1654	SPy1654	aapA	aapA	1373790	1375169	-	putative amino acid permease	Best Blastp hit %3D sp|O06005|AAPA_BACSU AMINO ACID PERMEASE AAPA >gi|7442346|pir||B69580 amino acid permease aapA - Bacillus subtilis >gi|2108260|emb|CAA63459.1| (X92868) amino acid permease [Bacillus subtilis] >gi|2635155|emb|CAB14651.1| (Z99117) amino acid permease [Bacillus subtilis]	gene	gene1360	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1654
SPy_1656	SPy1656		SPy_1656	1376319	1376543	-	hypothetical protein	Best Blastp hit %3D gb|AAD13390.1| (AF102861) retinoblastoma 1 [Oncorhynchus mykiss]	gene	gene1361	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1656
SPy_1657	SPy1657		SPy_1657	1376647	1377390	-	putative amino acid ABC transport system (ATP-binding protein)	Best Blastp hit %3D sp|P37774|YECC_ECOLI HYPOTHETICAL AMINO-ACID ABC TRANSPORTER ATP-BINDING PROTEIN YECC >gi|7442520|pir||B64955 ABC-type transport protein yecC - Escherichia coli >gi|1736576|dbj|BAA15737.1| (D90832) ORF_ID:o341#14%3B similar to [SwissProt Accession Number P37774] [Escherichia coli] >gi|1788225|gb|AAC74984.1| (AE000284) putative ATP-binding component of a transport system [Escherichia coli]	gene	gene1362	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1657
SPy_1658	SPy1658		SPy_1658	1377390	1378193	-	putative amino acid ABC transproter (permease protein)	Best Blastp hit %3D pir||B82376 amino acid ABC transporter%2C permease protein VC0009 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9654400|gb|AAF93187.1| (AE004093) amino acid ABC transproter%2C permease protein [Vibrio cholerae]	gene	gene1363	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1658
SPy_1659	SPy1659		SPy_1659	1378388	1379731	-	putative ATP-dependent RNA helicase	Best Blastp hit %3D dbj|BAB05104.1| (AP001511) ATP-dependent RNA helicase [Bacillus halodurans]	gene	gene1364	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1659
SPy_1662	SPy1662	mraY	mraY	1379889	1380899	-	putative undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase	Best Blastp hit %3D sp|Q9ZHA5|MRAY_STRPN PHOSPHO-N-ACETYLMURAMOYL-PENTAPEPTIDE-TRANSFERASE (UDP-MURNAC-PENTAPEPTIDE PHOSPHOTRANSFERASE) gb|AAC95457.1| (AF068903) undecaprenyl-phosphate-UDP-MurNAc-pentapeptide phospho-MurNAc-pentapeptide transferase [Streptococcus pneumoniae]	gene	gene1365	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1662
SPy_1664	SPy1664	pbpX	pbpX	1380901	1383156	-	putative penicillin binding protein 2X	Best Blastp hit %3D gb|AAF17266.1|AF210756_1 (AF210756) penicillin-binding protein 2X [Streptococcus pneumoniae]	gene	gene1366	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1664
SPy_1665	SPy1665	ftsL	ftsL	1383160	1383483	-	putative cell division protein	Best Blastp hit %3D gb|AAC45632.1| (U94707) cell division protein [Enterococcus faecalis]	gene	gene1367	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1665
SPy_1666	SPy1666		SPy_1666	1383488	1384501	-	hypothetical protein	Best Blastp hit %3D emb|CAB01927.1| (Z79691) OrfD [Streptococcus pneumoniae]	gene	gene1368	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1666
SPy_1670	SPy1670	proA	proA	1384975	1386225	-	putative gamma-glutamyl phosphate reductase	Best Blastp hit %3D dbj|BAB05223.1| (AP001512) gamma-glutamyl phosphate reductase [Bacillus halodurans]	gene	gene1369	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1670
SPy_1672	SPy1672	proB	proB	1386218	1387039	-	putative gamma-glutamyl kinase	Best Blastp hit %3D pir||T06366 gamma-glutamyl kinase - tomato >gi|2078447|gb|AAB67876.1| (U27454) gamma-glutamyl kinase [Lycopersicon esculentum]	gene	gene1370	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1672
SPy_1673	SPy1673		SPy_1673	1387104	1388732	-	hypothetical protein	Best Blastp hit %3D dbj|BAA82604.1| (AB026827) sALK-4 [Ephydatia fluviatilis]	gene	gene1371	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1673
SPy_1674	SPy1674		SPy_1674	1388737	1389471	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||H71066 probable ATP-binding transport protein - Pyrococcus horikoshii >gi|3257647|dbj|BAA30330.1| (AP000005) 253aa long hypothetical ATP-binding transport protein [Pyrococcus horikoshii]	gene	gene1372	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1674
SPy_1675	SPy1675		SPy_1675	1389505	1389771	-	hypothetical protein	Best Blastp hit %3D gi|9625658 BALF4 late reading frame 9xNXT/S homologous to HSV1 glycoprotein B (Pellet et al%2C 1985)%2C CMV HFLF1 and RF 31 VZV (gpII) [Human herpesvirus 4] >gi|138191|sp|P03188|VGLB_EBV GLYCOPROTEIN GP110 PRECURSOR (GP115) >gi|73932|pir||QQBE1L glycoprotein B - human herpesvirus 4 (strain B95-8) >gi|1334914|emb|CAA24806.1| (V01555) BALF4 late reading frame 9xNXT/S homologous to HSV1 glycoprotein B (Pellet et al%2C 1985)%2C CMV HFLF1 and RF 31 VZV (gpII) [Human herpesvirus 4]	gene	gene1373	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1675
SPy_1676	SPy1676	tkt	tkt	1389964	1392099	-	putative transketolase	Best Blastp hit %3D sp|P45694|TKT_BACSU TRANSKETOLASE >gi|7433610|pir||G69723 transketolase (EC 2.2.1.1) tkt - Bacillus subtilis >gi|1405446|emb|CAA97616.1| (Z73234) transketolase [Bacillus subtilis] >gi|2634173|emb|CAB13673.1| (Z99113) transketolase [Bacillus subtilis]	gene	gene1374	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1676
SPy_1678	SPy1678		SPy_1678	1392167	1392811	-	putative transaldolase	Best Blastp hit %3D pir||G72394 transaldolase-related protein - Thermotoga maritima (strain MSB8) >gi|4980794|gb|AAD35383.1|AE001711_6 (AE001711) transaldolase-related protein [Thermotoga maritima]	gene	gene1375	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1678
SPy_1680	SPy1680		SPy_1680	1392937	1394436	-	putative transcriptional regulatory protein	Best Blastp hit %3D emb|CAB70613.1| (AJ133440) multigene regulator protein Mgc%2C putative [Streptococcus dysgalactiae subsp. equisimilis]	gene	gene1376	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1680
SPy_1681	SPy1681		SPy_1681	1394426	1395772	-	putative NADH peroxidase	Best Blastp hit %3D pdb|1JOA| Nadh Peroxidase With Cysteine-Sulfenic Acid	gene	gene1377	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1681
SPy_1682	SPy1682	glpF	glpF	1395880	1396581	-	putative glycerol uptake facilitator	Best Blastp hit %3D dbj|BAB04811.1| (AP001510) glycerol uptake facilitator [Bacillus halodurans]	gene	gene1378	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1682
SPy_1683	SPy1683	glpO	glpO	1396583	1398421	-	putative alpha-glycerophosphate oxidase	Best Blastp hit %3D gb|AAC34739.1| (U57498) alpha-glycerophosphate oxidase [Enterococcus casseliflavus]	gene	gene1379	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1683
SPy_1684	SPy1684	glpK	glpK	1398437	1399963	-	putative glycerol kinase	Best Blastp hit %3D sp|O34154|GLPK_ENTFA GLYCEROL KINASE (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE) (GLYCEROKINASE) (GK) >gi|2388637|gb|AAB69986.1| (U94356) glycerol kinase [Enterococcus faecalis]	gene	gene1380	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1684
SPy_1686	SPy1686		SPy_1686	1400323	1400775	-	hypothetical protein	Best Blastp hit %3D pir||F69859 conserved hypothetical protein ykoJ - Bacillus subtilis >gi|2632048|emb|CAA05607.1| (AJ002571) YkoJ [Bacillus subtilis] >gi|2633682|emb|CAB13185.1| (Z99110) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1381	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1686
SPy_1687	SPy1687		SPy_1687	1400842	1401099	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06072.1| (AP001515) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1382	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1687
SPy_1688	SPy1688	glyS	glyS	1401253	1403292	-	putative glycyl-tRNA synthetase (beta subunit)	Best Blastp hit %3D dbj|BAB05090.1| (AP001511) glycyl-tRNA synthetase (beta subunit) [Bacillus halodurans]	gene	gene1383	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1688
SPy_1689	SPy1689	glyQ	glyQ	1403670	1404587	-	putative glycyl-tRNA synthetase (alpha subunit)	Best Blastp hit %3D sp|P54380|SYGA_BACSU GLYCYL-TRNA SYNTHETASE ALPHA CHAIN (GLYCINE-TRNA LIGASE ALPHA CHAIN) (GLYRS) >gi|7437690|pir||A69636 glycine-tRNA ligase (EC 6.1.1.14) alpha chain glyQ - Bacillus subtilis >gi|1303828|dbj|BAA12484.1| (D84432) YqfJ [Bacillus subtilis] >gi|2634959|emb|CAB14456.1| (Z99116) glycyl-tRNA synthetase (alpha subunit) [Bacillus subtilis] >gi|2634973|emb|CAB14469.1| (Z99117) glycyl-tRNA synthetase (alpha subunit) [Bacillus subtilis]	gene	gene1384	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1689
SPy_1691	SPy1691		SPy_1691	1404959	1405513	-	hypothetical protein	Best Blastp hit %3D sp|P43984|Y318_HAEIN HYPOTHETICAL PROTEIN HI0318 >gi|1074349|pir||B64006 hypothetical protein HI0318 - Haemophilus influenzae (strain Rd KW20) >gi|1573288|gb|AAC21982.1| (U32717) conserved hypothetical protein [Haemophilus influenzae Rd]	gene	gene1385	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1691
SPy_1693	SPy1693		SPy_1693	1405624	1406463	-	putative reductase / dehydrogenase	Best Blastp hit %3D dbj|BAB17681.1| (AB034727) prostaglandin F synthase [Trypanosoma brucei]	gene	gene1386	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1693
SPy_1694	SPy1694	nagA	nagA	1406585	1407733	-	putative N-acetylglucosamine-6-phosphate deacetylase	Best Blastp hit %3D dbj|BAA89244.1| (AB024532) similar to Vibrio furnissii GlcNAc-6-phosphate deacetylase (Acc#:U65015) [Enterococcus seriolicida]	gene	gene1387	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1694
SPy_1695	SPy1695		SPy_1695	1407851	1409482	-	hypothetical protein	Best Blastp hit %3D pir||H71283 conserved hypothetical integral membrane protein TP0771 - syphilis spirochete >gi|3323079|gb|AAC65739.1| (AE001248) conserved hypothetical integral membrane protein [Treponema pallidum]	gene	gene1388	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1695
SPy_1697	SPy1697		SPy_1697	1409684	1410406	+	hypothetical protein	Best Blastp hit %3D sp|P16396|SUBE_BACSU MINOR EXTRACELLULAR PROTEASE EPR PRECURSOR >gi|67626|pir||SUBSMP serine proteinase (EC 3.4.21.-) epr precursor - Bacillus subtilis >gi|39900|emb|CAA37392.1| (X53307) prepropeptide (AA -27 to 618) [Bacillus subtilis] >gi|142894|gb|AAA22423.1| (M22407) extracellular protease precursor [Bacillus subtilis] >gi|413939|emb|CAA51571.1| (X73124) ipa-15r epr [Bacillus subtilis] >gi|2636375|emb|CAB15866.1| (Z99123) extracellular serine protease [Bacillus subtilis]	gene	gene1389	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1697
SPy_1698	SPy1698		SPy_1698	1410535	1411377	-	hypothetical protein	Best Blastp hit %3D pir||D69841 hypothetical protein yitS - Bacillus subtilis >gi|1620923|emb|CAB01833.1| (Z79580) putative ORF [Bacillus subtilis] >gi|2145412|emb|CAA70629.1| (Y09476) YitS [Bacillus subtilis] >gi|2633447|emb|CAB12951.1| (Z99109) yitS [Bacillus subtilis]	gene	gene1390	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1698
SPy_1699	SPy1699		SPy_1699	1411670	1412227	+	putative transcription regulator	Best Blastp hit %3D pir||D70655 probable regulatory protein - Mycobacterium tuberculosis (strain H37RV) >gi|1781101|emb|CAB06235.1| (Z83864) hypothetical protein Rv3855 [Mycobacterium tuberculosis]	gene	gene1391	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1699
SPy_1700	SPy1700		SPy_1700	1412263	1413087	-	hypothetical protein	Best Blastp hit %3D gb|AAF94522.1| (AE004216) conserved hypothetical protein [Vibrio cholerae]	gene	gene1392	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1700
SPy_1701	SPy1701		SPy_1701	1413089	1413694	-	hypothetical protein	Best Blastp hit %3D sp|O32216|YVGT_BACSU HYPOTHETICAL 21.7 KDA PROTEIN IN SSPG-SECG INTERGENIC REGION >gi|7449244|pir||A70041 conserved hypothetical protein yvgT - Bacillus subtilis >gi|2635859|emb|CAB15351.1| (Z99121) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1393	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1701
SPy_1704	SPy1704	lacD.1	lacD.1	1413903	1414880	-	putative tagatose 1%2C6-diphosphate aldolase	Best Blastp hit %3D sp|P26593|LACD_LACLA TAGATOSE 1%2C6-DIPHOSPHATE ALDOLASE (TAGATOSE-BISPHOSPHATE ALDOLASE) (D-TAGATOSE-1%2C6-BISPHOSPHATE ALDOLASE) >gi|97943|pir||D39778 LacD tagatose-1%2C6-diphosphate aldolase - Lactococcus lactis >gi|149396|gb|AAA25171.1| (M65190) lacD [Lactococcus lactis] >gi|149409|gb|AAA25180.1| (M60447) tagatose 1%2C6-diP aldolase [Lactococcus lactis]	gene	gene1394	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1704
SPy_1705	SPy1705	lacC.1	lacC.1	1414863	1415380	-		Tagatose-6-phosphate kinase%3B This appears to encode only the N-terminus of the gene. There are also several sequence confirmed frame shift mutations within the gene	gene	gene1395	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1705
SPy_1707	SPy1707	lacB.1	lacB.1	1415390	1415905	-	putative galactose-6-phosphate isomerase	Best Blastp hit %3D sp|P26592|LACB_STAAU GALACTOSE-6-PHOSPHATE ISOMERASE LACB SUBUNIT >gi|97815|pir||B38158 galactose-6-phosphate isomerase 19K chain - Staphylococcus aureus >gi|153033|gb|AAA26641.1| (M64724) tagatose 6-phosphate isomerase [Staphylococcus aureus]	gene	gene1396	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1707
SPy_1708	SPy1708	lacA.1	lacA.1	1415920	1416345	-	putative galactose-6-phosphate isomerase	Best Blastp hit %3D sp|P26594|LACA_STAAU GALACTOSE-6-PHOSPHATE ISOMERASE LACA SUBUNIT >gi|97814|pir||A38158 galactose-6-phosphate isomerase (EC 5.1.3.-) 15K chain - Staphylococcus aureus	gene	gene1397	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1708
SPy_1709	SPy1709		SPy_1709	1416585	1418033	-	putative PTS system%2C enzyme IIC component	Best Blastp hit %3D dbj|BAA75340.1| (AB011837) PTS system galactitol-specific enzyme IIC component [Bacillus halodurans] >gi|10172802|dbj|BAB03909.1| (AP001507) PTS system%2C galactitol-specific enzyme II%2C C component [Bacillus halodurans]	gene	gene1398	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1709
SPy_1710	SPy1710		SPy_1710	1418062	1418367	-	putative PTS system%2C enzyme IIB component	Best Blastp hit %3D gb|AAG09978.1|AF248038_7 (AF248038) GatB [Streptococcus agalactiae]	gene	gene1399	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1710
SPy_1711	SPy1711		SPy_1711	1418360	1418833	-	putative PTS system%2C enzyme IIA component	Best Blastp hit %3D dbj|BAA75339.1| (AB011837) phosphotransferase system (PTS) fructose-specific enzyme IIBC component [Bacillus halodurans] >gi|10172804|dbj|BAB03911.1| (AP001507) PTS system%2C galactitol-specific enzyme II%2C A component [Bacillus halodurans]	gene	gene1400	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1711
SPy_1712	SPy1712	lacR.1	lacR.1	1419070	1419840	+	putative lactose phosphotransferase system repressor protein	Best Blastp hit %3D sp|P18816|LACR_LACLA LACTOSE PHOSPHOTRANSFERASE SYSTEM REPRESSOR >gi|149403|gb|AAA25175.1| (M35375) lactose repressor (lacR%3B alt.) [Lactococcus lactis]	gene	gene1401	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1712
SPy_1714	SPy1714	copZ	copZ	1420044	1420247	-	putative copper chaperone - copper transport operon	Best Blastp hit %3D sp||MERA_SERMA_1 [Segment 1 of 2] MERCURIC REDUCTASE (HG(II) REDUCTASE) >gi|551917|gb|AAA98224.1| (M24940) mercury resistance protein [Plasmid pDU1358]	gene	gene1402	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1714
SPy_1715	SPy1715	copA	copA	1420261	1422462	-	putative cation-transporting ATP-ase - copper transport operon	Best Blastp hit %3D sp|P37279|ATCS_SYNP7 CATION-TRANSPORTING ATPASE PACS >gi|480354|pir||S36741 probable copper-transporting ATPase (EC 3.6.1.-) pacS - Synechococcus sp >gi|435125|dbj|BAA03907.1| (D16437) PacS [Synechococcus sp.]	gene	gene1403	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1715
SPy_1717	SPy1717	copY	copY	1422492	1422926	-	putative negative transcriptional regulator - cpooer transport operon	Best Blastp hit %3D sp|O07127|YPTY_LACSK HYPOTHETICAL 16.5 KD PROTEIN IN PTSI 3'REGION (ORFY) >gi|2149153|gb|AAC45392.1| (U82366) similar to CopY%2C the negative regulator of copYZAB operon of Enterococcus hirae%3B ORFY [Lactobacillus sakei] >gi|7546786|gb|AAF63679.1|AF172726_2 (AF172726) AtkY [Lactobacillus sakei]	gene	gene1404	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1717
SPy_1718	SPy1718		SPy_1718	1423098	1424084	+	putative esterase	Best Blastp hit %3D gb|AAF87664.1|AF223647_1 (AF223647) esterase [uncultured bacterium]	gene	gene1405	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1718
SPy_1719	SPy1719	rbfA	rbfA	1424218	1424574	-	putative ribosome binding factor A	Best Blastp hit %3D emb|CAC00494.1| (AJ251497) ribosome binding factor A [Streptococcus agalactiae] >gi|9558385|emb|CAC00496.1| (AJ251498) ribosome binding factor A [Streptococcus agalactiae]	gene	gene1406	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1719
SPy_1721	SPy1721	infB	infB	1424773	1427634	-	putative initiation factor 2	Best Blastp hit %3D sp|Q9ZF20|IF2_STRAG TRANSLATION INITIATION FACTOR IF-2 >gi|3947714|emb|CAA05919.1| (AJ003164) initiation factor IF2 [Streptococcus agalactiae] >gi|9558375|emb|CAC00489.1| (AJ251495) initiation factor 2 [Streptococcus agalactiae] >gi|9558378|emb|CAC00491.1| (AJ251496) initiation factor 2 [Streptococcus agalactiae]	gene	gene1407	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1721
SPy_1722	SPy1722		SPy_1722	1427654	1427956	-	putative ribosomal protein	Best Blastp hit %3D sp|P32729|YLXQ_BACSU PROBABLE RIBOSOMAL PROTEIN IN NUSA-INFB INTERGENIC REGION (ORF4) >gi|541415|pir||E36905 ribosomal protein L7AE family homolog ylxQ - Bacillus subtilis >gi|49318|emb|CAA79233.1| (Z18631) ORF4 [Bacillus subtilis] >gi|2634034|emb|CAB13535.1| (Z99112) alternate gene name: ymxC~similar to ribosomal protein L7AE family [Bacillus subtilis]	gene	gene1408	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1722
SPy_1723	SPy1723		SPy_1723	1427949	1428245	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06134.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1409	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1723
SPy_1724	SPy1724	nusA	nusA	1428261	1429418	-	transcription termination-antitermination factor	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||C36905 transcription termination-antitermination factor nusA - Bacillus subtilis >gi|49316|emb|CAA79231.1| (Z18631) ORF2 [Bacillus subtilis]	gene	gene1410	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1724
SPy_1725	SPy1725		SPy_1725	1429593	1429976	-	hypothetical protein	Best Blastp hit %3D sp|P32726|YLXS_BACSU HYPOTHETICAL 17.6 KDA PROTEIN IN NUSA 5'REGION (P15A) (ORF1) >gi|541417|pir||B36905 conserved hypothetical protein ylxS - Bacillus subtilis >gi|49315|emb|CAA79230.1| (Z18631) ORF1 [Bacillus subtilis] >gi|2634031|emb|CAB13532.1| (Z99112) alternate gene name: ymxA~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1411	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1725
SPy_1726	SPy1726		SPy_1726	1430388	1431023	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06980.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene1413	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1726
SPy_1727	SPy1727		SPy_1727	1431023	1431814	-	hypothetical protein	Best Blastp hit %3D emb|CAB82476.1| (Y14816) hypothetical protein [Staphylococcus aureus]	gene	gene1414	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1727
SPy_1728	SPy1728		SPy_1728	1431878	1432912	-	putative ABC transporter (permease)	Best Blastp hit %3D dbj|BAB04911.1| (AP001511) ABC transporter (permease) [Bacillus halodurans]	gene	gene1415	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1728
SPy_1729	SPy1729		SPy_1729	1432915	1433640	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB04910.1| (AP001511) ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1416	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1729
SPy_1730	SPy1730	hit	hit	1433712	1434131	+	putative cell-cycle regulation histidine triad (HIT) protein	Best Blastp hit %3D sp|O07513|HIT_BACSU HIT PROTEIN >gi|7434513|pir||A69642 cell-cycle regulation histidine triad (HIT) protein - Bacillus subtilis >gi|2226116|emb|CAA74410.1| (Y14077) Hypothetical protein [Bacillus subtilis] >gi|2633339|emb|CAB12843.1| (Z99109) Hit-like protein [Bacillus subtilis]	gene	gene1417	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1730
SPy_1731	SPy1731		SPy_1731	1434128	1434484	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1418	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1731
SPy_1733	SPy1733		SPy_1733	1434595	1435869	-	putative transcription regulator	Best Blastp hit %3D dbj|BAB07389.1| (AP001519) attenuator for lytABC and lytR expression [Bacillus halodurans]	gene	gene1419	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1733
SPy_1734	SPy1734		SPy_1734	1435878	1436402	-	hypothetical protein	Best Blastp hit %3D pir||D72360 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981094|gb|AAD35662.1|AE001732_7 (AE001732) conserved hypothetical protein [Thermotoga maritima]	gene	gene1420	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1734
SPy_1735	SPy1735		SPy_1735	1436377	1436838	-	hypothetical protein	Best Blastp hit %3D sp|O05515|YDIB_BACSU HYPOTHETICAL 17.9 KDA PROTEIN IN PHOB-GROES INTERGENIC REGION >gi|7450018|pir||C69786 conserved hypothetical protein ydiB - Bacillus subtilis >gi|1945107|dbj|BAA19715.1| (D88802) E. coli hypothetical protein%3B P31805 (267) [Bacillus subtilis] >gi|2632904|emb|CAB12410.1| (Z99107) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1421	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1735
SPy_1736	SPy1736		SPy_1736	1436992	1438452	-	hypothetical protein	Best Blastp hit %3D pir||B82096 conserved hypothetical protein VC2278 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9656841|gb|AAF95422.1| (AE004299) conserved hypothetical protein [Vibrio cholerae]	gene	gene1422	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1736
SPy_1737	SPy1737		SPy_1737	1438716	1439528	+	hypothetical protein	Best Blastp hit %3D pir||F69841 conserved hypothetical protein yitU - Bacillus subtilis >gi|1620926|emb|CAB01836.1| (Z79580) putative orf [Bacillus subtilis] >gi|2145415|emb|CAA70632.1| (Y09476) YitU [Bacillus subtilis] >gi|2633450|emb|CAB12954.1| (Z99109) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1423	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1737
SPy_1738	SPy1738	manL	manL	1439880	1440872	+	mannose-specific phosphotransferase system component IIAB	Best Blastp hit %3D gb|AAD46485.1|AF130465_1 (AF130465) mannose-specific phosphotransferase system component IIAB [Streptococcus salivarius]	gene	gene1424	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1738
SPy_1739	SPy1739	manM	manM	1440961	1441770	+	putative mannose-specific phosphotransferase system component IIC	Best Blastp hit %3D gb|AAD46486.1|AF130465_2 (AF130465) mannose-specific phosphotransferase system component IIC [Streptococcus salivarius]	gene	gene1425	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1739
SPy_1740	SPy1740	manN	manN	1441787	1442698	+	putative mannose-specific phosphotransferase system component IID	Best Blastp hit %3D gb|AAD46487.1|AF130465_3 (AF130465) mannose-specific phosphotransferase system component IID [Streptococcus salivarius]	gene	gene1426	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1740
SPy_1741	SPy1741		SPy_1741	1442812	1443171	+	hypothetical protein	Best Blastp hit %3D gb|AAD46488.1|AF130465_4 (AF130465) unknown [Streptococcus salivarius]	gene	gene1427	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1741
SPy_1742	SPy1742	serS	serS	1443563	1444840	+	putative seryl-tRNA synthetase	Best Blastp hit %3D dbj|BAB03743.1| (AP001507) seryl-tRNA synthetase [Bacillus halodurans]	gene	gene1428	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1742
SPy_1743	SPy1743	accA	accA	1445062	1445832	-	putative acetyl-CoA carboxylase alpha subunit	Best Blastp hit %3D dbj|BAB06884.1| (AP001517) acetyl-CoA carboxylase carboxyltransferase alpha subunit [Bacillus halodurans]	gene	gene1429	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1743
SPy_1744	SPy1744	accD	accD	1445829	1446695	-	putative acetyl-CoA carboxylase beta subunit	Best Blastp hit %3D sp|Q54776|ACCD_SYNP7 ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE SUBUNIT BETA (ACCASE BETA CHAIN) >gi|1399855|gb|AAB82034.1| (U59237) carboxyltransferase beta subunit [Synechococcus PCC7942]	gene	gene1430	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1744
SPy_1745	SPy1745	accC	accC	1446704	1448068	-	putative acetyl-CoA carboxylase biotin carboxylase subunit	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||A69581 acetyl-CoA carboxylase (biotin carboxylase subunit) accC - Bacillus subtilis >gi|1303913|dbj|BAA12569.1| (D84432) YqhX [Bacillus subtilis] >gi|2634868|emb|CAB14365.1| (Z99116) acetyl-CoA carboxylase subunit (biotin carboxylase subunit) [Bacillus subtilis]	gene	gene1431	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1745
SPy_1746	SPy1746	fabZ	fabZ	1448100	1448519	-	putative beta-hydroxyacyl-ACP dehydratase	Best Blastp hit %3D dbj|BAB16042.1| (AB030883) similar to Bacillus subtilis hydroxymyristoyl-(acyl carrier protein) dehydratase [Streptococcus zooepidemicus]	gene	gene1432	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1746
SPy_1747	SPy1747	accB	accB	1448519	1449019	-	putative biotoin carboxyl carrier protein	Best Blastp hit %3D pir||C75558 acetyl-CoA carboxylase%2C bitoin carboxyl carrier protein - Deinococcus radiodurans (strain R1) >gi|6457783|gb|AAF09708.1|AE001874_5 (AE001874) acetyl-CoA carboxylase%2C bitoin carboxyl carrier protein [Deinococcus radiodurans]	gene	gene1433	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1747
SPy_1748	SPy1748	fabF	fabF	1449021	1450253	-	putative beta-ketoacyl-ACP synthase II	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pir||G69842 3-oxoacyl-[acyl-carrier-protein] synthase (EC 2.3.1.41) - Bacillus subtilis >gi|2633471|emb|CAB12975.1| (Z99109) similar to 3-oxoacyl- acyl-carrier protein synthase [Bacillus subtilis] >gi|2633488|emb|CAB12991.1| (Z99110) similar to 3-oxoacyl- acyl-carrier protein synthase [Bacillus subtilis]	gene	gene1434	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1748
SPy_1749	SPy1749	fabG	fabG	1450268	1451002	-	putative beta-ketoacyl-ACP reductase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB06210.1| (AP001515) 3-oxoacyl-(acyl-carrier protein) reductase [Bacillus halodurans]	gene	gene1435	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1749
SPy_1750	SPy1750	fabD	fabD	1450992	1451930	-	putative malonyl CoA-acyl carrier protein transacylase	Best Blastp hit %3D sp|P71019|FABD_BACSU MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE (MCT) >gi|7433733|pir||H69620 [acyl-carrier-protein] S-malonyltransferase (EC 2.3.1.39) fabD [validated] - Bacillus subtilis >gi|2337819|emb|CAA74249.1| (Y13937) putative FabD protein [Bacillus subtilis] >gi|2633962|emb|CAB13463.1| (Z99112) malonyl CoA-acyl carrier protein transacylase [Bacillus subtilis]	gene	gene1436	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1750
SPy_1751	SPy1751	fabK	fabK	1451955	1452926	-	putative trans-2-enoyl-ACP reductase II	Best Blastp hit %3D pir||A72335 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4981329|gb|AAD35882.1|AE001747_25 (AE001747) conserved hypothetical protein [Thermotoga maritima]	gene	gene1437	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1751
SPy_1753	SPy1753	acpP	acpP	1453128	1453352	-	putative acyl carrier protein	Best Blastp hit %3D sp|O67611|ACP_AQUAE ACYL CARRIER PROTEIN (ACP) >gi|7442262|pir||A70448 acyl carrier protein - Aquifex aeolicus >gi|2984024|gb|AAC07567.1| (AE000752) acyl carrier protein [Aquifex aeolicus]	gene	gene1438	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1753
SPy_1754	SPy1754	fabH	fabH	1453413	1454387	-	putative beta-ketoacyl-[ACP] synthase III	Best Blastp hit %3D pir||H82633 beta-ketoacyl-[ACP] synthase III XF1817 [imported] - Xylella fastidiosa (strain 9a5c) >gi|9106896|gb|AAF84623.1|AE004003_2 (AE004003) beta-ketoacyl-[ACP] synthase III [Xylella fastidiosa]	gene	gene1439	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1754
SPy_1755	SPy1755		SPy_1755	1454388	1454822	-	putative transcriptional regulator (MarR family)	Best Blastp hit %3D sp|P40762|YVMB_BACSU HYPOTHETICAL 19.7 KDA PROTEIN IN CYPX-UVRA INTERGENIC REGION >gi|629106|pir||S47218 conserved hypothetical protein yvmB - Bacillus subtilis >gi|535052|emb|CAA85355.1| (Z36881) involved in protein secretion [Bacillus subtilis] >gi|2618849|gb|AAC67278.1| (AF017113) YzhA [Bacillus subtilis] >gi|2636021|emb|CAB15513.1| (Z99121) alternate gene name: yzhA~similar to hypothetical proteins [Bacillus subtilis] >gi|2636034|emb|CAB15525.1| (Z99122) alternate gene name: yzhA~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1440	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1755
SPy_1758	SPy1758	phaB	phaB	1454899	1455690	-	putative enoyl CoA hydratase	Best Blastp hit %3D gb|AAC24330.1| (AF029714) PhaB [Pseudomonas putida]	gene	gene1441	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1758
SPy_1759	SPy1759	dnaJ	dnaJ	1455910	1457046	-	heat-shock (chaperone) protein	Best Blastp hit %3D sp|P95830|DNAJ_STRPN CHAPERONE PROTEIN DNAJ >gi|1750265|gb|AAB39222.1| (U72720) DnaJ [Streptococcus pneumoniae]	gene	gene1442	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1759
SPy_1760	SPy1760	dnaK	dnaK	1457327	1459153	-	heat shock protein 70	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P95693|DNAK_STRAG DNAK PROTEIN (HEAT SHOCK PROTEIN 70) (HSP70) >gi|1750261|gb|AAB39219.1| (U72719) heat shock protein 70 [Streptococcus agalactiae]	gene	gene1443	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1760
SPy_1761	SPy1761	grpE	grpE	1459334	1459906	-	putative Hsp-70 cofactor	Best Blastp hit %3D pir||S39341 grpE protein - Lactococcus lactis	gene	gene1444	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1761
SPy_1763	SPy1763	hrcA	hrcA	1459909	1460943	-	putative heat shock transcription repressor protein	Best Blastp hit %3D gb|AAC45610.1| (U78296) repressor of class I heat shock gene expression HrcA [Streptococcus mutans]	gene	gene1445	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1763
SPy_1764	SPy1764		SPy_1764	1461078	1461647	-	putative N-acetyl-muramidase	Best Blastp hit %3D pir||H70006 N-acetylmuramoyl-L-alanine amidase homolog yubE - Bacillus subtilis >gi|2635596|emb|CAB15090.1| (Z99119) similar to N-acetylmuramoyl-L-alanine amidase [Bacillus subtilis]	gene	gene1446	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1764
SPy_1765	SPy1765		SPy_1765	1461644	1462387	-	putative D%2CD-carboxypeptidase	Best Blastp hit %3D gb|AAF72360.1|AF192329_21 (AF192329) VanYB [Enterococcus faecalis]	gene	gene1447	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1765
SPy_1766	SPy1766		SPy_1766	1462377	1463084	-	putative phosphoglycerate mutase	Best Blastp hit %3D gb|AAF55985.1| (AE003738) CG7059 gene product [Drosophila melanogaster]	gene	gene1448	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1766
SPy_1768	SPy1768		SPy_1768	1463475	1463714	-	hypothetical protein	Best Blastp hit %3D pir||F70070 conserved hypothetical protein ywzA - Bacillus subtilis >gi|2636353|emb|CAB15844.1| (Z99123) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1449	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1768
SPy_1769	SPy1769		SPy_1769	1463933	1464148	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1450	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1769
SPy_1770	SPy1770	gatB	gatB	1464145	1465584	-	putative Glu-tRNAGln amidotransferase subunit B	Best Blastp hit %3D gb|AAF18137.1|AF205033_3 (AF205033) glutamyl-tRNAGln amidotransferase subunit B [Staphylococcus aureus]	gene	gene1451	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1770
SPy_1771	SPy1771	gatA	gatA	1465584	1467050	-	putative Glutamyl-tRNA Gln amidotransferase subunit A	Best Blastp hit %3D sp|O06491|GATA_BACSU GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT A (GLU-ADT SUBUNIT A) >gi|7436459|pir||B69795 glutamyl-tRNA(Gln) amidotransferase (EC 2.6.-.-) chain A [validated] - Bacillus subtilis >gi|2632982|emb|CAB12488.1| (Z99107) alternate gene name: yedB~similar to amidase [Bacillus subtilis]	gene	gene1452	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1771
SPy_1772	SPy1772	gatC	gatC	1467050	1467352	-	putative Glu-tRNA Gln amidotransferase subunit C	Best Blastp hit %3D sp|O06492|GATC_BACSU GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE SUBUNIT C (GLU-ADT SUBUNIT C) >gi|7450327|pir||A69795 glutamyl-tRNA(Gln) amidotransferase (EC 2.6.-.-) chain C [validated] - Bacillus subtilis >gi|2114425|gb|AAB66514.1| (U92466) similar to Synechocystis sp. hypothetical protein%2C encoded by GenBank Accession Number D64006 [Bacillus subtilis] >gi|2589194|gb|AAB83963.1| (AF008553) Glu-tRNAGln amidotransferase subunit C [Bacillus subtilis] >gi|2632981|emb|CAB12487.1| (Z99107) alternate gene name: yedA~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1453	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1772
SPy_1776	SPy1776		SPy_1776	1468347	1468901	-	putative pyrazinamidase/nicotinamidase	Best Blastp hit %3D dbj|BAB07496.1| (AP001520) pyrazinamidase/nicotinamidase [Bacillus halodurans]	gene	gene1454	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1776
SPy_1777	SPy1777	codY	codY	1469048	1469830	-	putative transcriptional pleiotropic repressor	Best Blastp hit %3D dbj|BAB06181.1| (AP001515) transcriptional pleiotropic repressor [Bacillus halodurans]	gene	gene1455	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1777
SPy_1779	SPy1779		SPy_1779	1470048	1471262	-	putative aminotransferase	Best Blastp hit %3D sp|P77727|YFBQ_ECOLI PROBABLE AMINOTRANSFERASE YFBQ >gi|7447846|pir||H65000 probable transaminase (EC 2.6.1.-) b2290 [similarity] - Escherichia coli (strain K-12) >gi|1788627|gb|AAC75350.1| (AE000318) putative aminotransferase [Escherichia coli] >gi|1799660|dbj|BAA16127.1| (D90860) ASPARTATE AMINOTRANSFERASE (EC 2.6.1.1) (TRANSAMINASE A) (ASPAT). [Escherichia coli]	gene	gene1456	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1779
SPy_1780	SPy1780		SPy_1780	1471439	1471945	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06903.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene1457	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1780
SPy_1781	SPy1781		SPy_1781	1472068	1473456	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06378.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene1458	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1781
SPy_1782	SPy1782	asnB	asnB	1473528	1474493	+	putative L-asparaginase	Best Blastp hit %3D dbj|BAB05343.1| (AP001512) L-asparaginase [Bacillus halodurans]	gene	gene1459	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1782
SPy_1783	SPy1783		SPy_1783	1474842	1475546	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1460	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1783
SPy_1784	SPy1784		SPy_1784	1475559	1476461	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D gb|AAC43327.1| (U17255) NisF [Lactococcus lactis] >gi|1095449|prf||2109193A nisF gene [Lactococcus lactis]	gene	gene1461	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1784
SPy_1785	SPy1785	recG	recG	1476754	1478769	-	putative ATP-dependent DNA helicase	Best Blastp hit %3D sp|O34942|RECG_BACSU ATP-DEPENDENT DNA HELICASE RECG >gi|7428321|pir||H69879 ATP-dependent DNA helicase homolog ylpB - Bacillus subtilis >gi|2337816|emb|CAA74246.1| (Y13937) putative RecG protein [Bacillus subtilis] >gi|2633959|emb|CAB13460.1| (Z99112) similar to ATP-dependent DNA helicase [Bacillus subtilis]	gene	gene1462	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1785
SPy_1787	SPy1787		SPy_1787	1479144	1480538	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||H69858 cation ABC transporter (ATP-binding protei) homolog ykoD - Bacillus subtilis >gi|2632042|emb|CAA05601.1| (AJ002571) YkoD [Bacillus subtilis] >gi|2633676|emb|CAB13179.1| (Z99110) similar to cation ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene1463	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1787
SPy_1788	SPy1788		SPy_1788	1480535	1481215	-	hypothetical protein	Best Blastp hit %3D pir||F69742 hypothetical protein ybaF - Bacillus subtilis >gi|2632414|emb|CAB11923.1| (Z99104) ybaF [Bacillus subtilis]	gene	gene1464	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1788
SPy_1789	SPy1789		SPy_1789	1481212	1481805	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1465	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1789
SPy_1790	SPy1790		SPy_1790	1481802	1483472	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P45081|CYDC_HAEIN TRANSPORT ATP-BINDING PROTEIN CYDC >gi|1075388|pir||E64186 probable ATP-binding transport protein HI1156 - Haemophilus influenzae (strain Rd KW20) >gi|1574713|gb|AAC22811.1| (U32795) transport ATP-binding protein (cydC) [Haemophilus influenzae Rd]	gene	gene1466	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1790
SPy_1791	SPy1791		SPy_1791	1483465	1485228	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB07690.1| (AP001520) ABC transporter required for expression of cytochrome bd (ATP-binding protein) [Bacillus halodurans]	gene	gene1467	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1791
SPy_1793	SPy1793		SPy_1793	1485225	1486061	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB07014.1| (AP001518) ferrichrome ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1468	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1793
SPy_1794	SPy1794		SPy_1794	1486058	1487080	-	putative ABC transporter (permease)	Best Blastp hit %3D dbj|BAB07010.1| (AP001518) ferrichrome ABC transporter (permease) [Bacillus halodurans]	gene	gene1469	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1794
SPy_1795	SPy1795		SPy_1795	1487082	1487966	-	putative ABC transporter (periplasmic binding protein)	Best Blastp hit %3D dbj|BAB07009.1| (AP001518) ferrichrome ABC transporter (ferrichrome-binding protein) [Bacillus halodurans]	gene	gene1470	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1795
SPy_1796	SPy1796		SPy_1796	1487950	1488825	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1471	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1796
SPy_1798	SPy1798		SPy_1798	1489022	1492849	-	hypothetical protein sharing similarity with several eukaryotic proteins	Best Blastp hit %3D gb|AAF53254.1| (AE003639) CG16974 gene product [Drosophila melanogaster]	gene	gene1472	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1798
SPy_1801	SPy1801	isp2	isp2	1493338	1494849	-	immunogenic secreted precursor-like protein	Best Blastp hit %3D emb|CAB70620.1| (AJ243106) transfer protein [Streptococcus thermophilus]	gene	gene1473	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1801
SPy_1802	SPy1802	alr	alr	1494936	1496036	-	putative alanine racemase	Best Blastp hit %3D sp|O08445|ALR_LACPL ALANINE RACEMASE >gi|2190422|emb|CAA70140.1| (Y08941) alanine racemase [Lactobacillus plantarum]	gene	gene1474	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1802
SPy_1804	SPy1804	acpS	acpS	1496033	1496389	-	putative holo-(acyl carrier protein) synthase	Best Blastp hit %3D dbj|BAB04237.1| (AP001508) holo-(acyl carrier protein) synthase [Bacillus halodurans]	gene	gene1475	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1804
SPy_1805	SPy1805	secA	secA	1496505	1499024	-	putative preprotein translocase binding subunit (ATPase)	Best Blastp hit %3D sp|P28366|SECA_BACSU PREPROTEIN TRANSLOCASE SECA SUBUNIT >gi|80260|pir||JQ0647 preprotein translocase secA - Bacillus subtilis >gi|216334|dbj|BAA01122.1| (D10279) secA protein [Bacillus subtilis] >gi|1762349|gb|AAC44957.1| (U56901) involved in protein export [Bacillus subtilis] >gi|2636056|emb|CAB15547.1| (Z99122) translocase binding subunit (ATPase) [Bacillus subtilis]	gene	gene1476	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1805
SPy_1806	SPy1806		SPy_1806	1499102	1499185	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1477	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1806
SPy_1807	SPy1807		SPy_1807	1499190	1500323	-	putative transposase - IS1548	Best Blastp hit %3D gb|AAD00760.1| (U93592) putative transposase [Vibrio anguillarum]	gene	gene1478	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1807
SPy_1810	SPy1810	pmi	pmi	1500485	1501438	-	putative mannose-6-phosphate isomerase	Best Blastp hit %3D dbj|BAA75351.1| (AB011838) mannnose-6 phospate isomelase [Bacillus halodurans] >gi|10176541|dbj|BAB07635.1| (AP001520) mannose-6-phosphate isomerase [Bacillus halodurans]	gene	gene1479	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1810
SPy_1811	SPy1811	scrK	scrK	1501533	1502417	-	putative fructokinase	Best Blastp hit %3D sp|P82371|SCRK_LACLC FRUCTOKINASE >gi|4581478|emb|CAB09691.1| (Z97015) fructokinase [Lactococcus lactis]	gene	gene1480	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1811
SPy_1813	SPy1813		SPy_1813	1502681	1505668	-	hypothetical protein	Best Blastp hit %3D pir||I40873 serine proteinase 40 (EC 3.4.21.-) precursor - Corynebacterium pseudotuberculosis >gi|531383|gb|AAA67924.1| (U10424) serine proteinase precursor [Corynebacterium pseudotuberculosis]	gene	gene1481	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1813
SPy_1815	SPy1815	scrA	scrA	1505899	1507782	-	putative sucrose-specific PTS permease%2C enzyme II	Best Blastp hit %3D gb|AAC99320.1| (AF059741) sucrose-specific PTS permease [Clostridium beijerinckii]	gene	gene1482	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1815
SPy_1816	SPy1816	scrB	scrB	1508024	1509463	+	putative sucrose-6-phosphate hydrolase	Best Blastp hit %3D pir||S68598 sucrose-6-phosphate hydrolase ScrB - Streptococcus sobrinus (strain 6715)	gene	gene1483	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1816
SPy_1817	SPy1817	scrR	scrR	1509468	1510433	+	putative sucrose operon repressor	Best Blastp hit %3D sp|Q54430|SCRR_STRMU SUCROSE OPERON REPRESSOR (SCR OPERON REGULATORY PROTEIN) >gi|1184967|gb|AAC31628.1| (U46902) ScrR [Streptococcus mutans]	gene	gene1484	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1817
SPy_1818	SPy1818	nusB	nusB	1510574	1511026	-	putative transcriptional terminator	Best Blastp hit %3D dbj|BAB06504.1| (AP001516) transcriptional terminator [Bacillus halodurans]	gene	gene1485	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1818
SPy_1820	SPy1820		SPy_1820	1511019	1511408	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06505.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene1486	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1820
SPy_1821	SPy1821	efp	efp	1511454	1512011	-	putative translation elongation factor EF-P	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB06518.1| (AP001516) translation elongation factor EF-P [Bacillus halodurans]	gene	gene1487	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1821
SPy_1823	SPy1823	comEB	comEB	1512107	1512568	-	putative late competence protein required for DNA binding	Best Blastp hit %3D sp|P32393|CME2_BACSU COME OPERON PROTEIN 2 >gi|541404|pir||S39864 late competence operon required for DNA binding and uptake comEB - Bacillus subtilis >gi|289261|gb|AAC36906.1| (L15202) comE ORF2 [Bacillus subtilis] >gi|1303797|dbj|BAA12453.1| (D84432) ComEB [Bacillus subtilis] >gi|2635004|emb|CAB14500.1| (Z99117) alternate gene name: comD [Bacillus subtilis]	gene	gene1488	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1823
SPy_1824	SPy1824	pepP	pepP	1512603	1513676	-	putative aminopeptidase P%3B XAA-pro aminopeptidase	Best Blastp hit %3D sp|P54518|YQHT_BACSU PUTATIVE PEPTIDASE IN GCVT-SPOIIIAA INTERGENIC REGION >gi|7430115|pir||C69960 Xaa-Pro dipeptidase homolog yqhT - Bacillus subtilis >gi|1303901|dbj|BAA12557.1| (D84432) YqhT [Bacillus subtilis] >gi|2634880|emb|CAB14377.1| (Z99116) similar to Xaa-Pro dipeptidase [Bacillus subtilis]	gene	gene1489	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1824
SPy_1825	SPy1825	uvrA	uvrA	1513791	1516619	-	putative excinuclease ABC (subunit A)	Best Blastp hit %3D dbj|BAB07313.1| (AP001519) excinuclease ABC (subunit A) [Bacillus halodurans]	gene	gene1490	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1825
SPy_1827	SPy1827		SPy_1827	1516822	1517766	+	putative divalent cation transport protein	Best Blastp hit %3D pir||A75272 probable transport protein - Deinococcus radiodurans (strain R1) >gi|6460278|gb|AAF12002.1|AE002075_6 (AE002075) transport protein%2C putative [Deinococcus radiodurans]	gene	gene1491	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1827
SPy_1828	SPy1828		SPy_1828	1517899	1518555	+	hypothetical protein	Best Blastp hit %3D gb|AAG06529.1|AE004738_3 (AE004738) nucleotide sugar epimerase/dehydratase WbpM [Pseudomonas aeruginosa]	gene	gene1492	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1828
SPy_1829	SPy1829	rpsR	rpsR	1518688	1518927	-	30S ribosomal protein S18	Best Blastp hit %3D sp|P10806|RS18_BACST 30S RIBOSOMAL PROTEIN S18 (BS21)	gene	gene1493	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1829
SPy_1830	SPy1830		SPy_1830	1519092	1519583	-	putative single strand binding protein - phage associated	Best Blastp hit %3D gi|9634636 ORF9 [Streptococcus thermophilus bacteriophage 7201] >gi|6716352|gb|AAF26608.1|AF118440_6 (AF145054) ORF9 [Streptococcus thermophilus bacteriophage 7201]	gene	gene1494	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1830
SPy_1831	SPy1831	rpsF	rpsF	1519605	1519895	-	30S ribosomal protein S6	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|Q9K5N8|RS6_BACHD 30S RIBOSOMAL PROTEIN S6 >gi|10176675|dbj|BAB07769.1| (AP001520) ribosomal protein S6 (BS9) [Bacillus halodurans]	gene	gene1495	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1831
SPy_1832	SPy1832		SPy_1832	1520068	1520361	-	hypothetical protein	Best Blastp hit %3D gb|AAB70415.1| (AC000106) Similar to Beta integral membrane protein (gb|U43629). [Arabidopsis thaliana]	gene	gene1496	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1832
SPy_1833	SPy1833	mutY	mutY	1520559	1521683	+	putative A/G-specific adenine glycosylase	Best Blastp hit %3D pir||A69802 A/G-specific adenine glycosylase homolog yfhQ - Bacillus subtilis >gi|2633186|emb|CAB12691.1| (Z99108) similar to A/G-specific adenine glycosylase [Bacillus subtilis] >gi|2804547|dbj|BAA24483.1| (D85082) YfhQ [Bacillus subtilis]	gene	gene1497	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1833
SPy_1834	SPy1834		SPy_1834	1521759	1522346	+	hypothetical protein	Best Blastp hit %3D pir||I40868 hypothetical protein 3 nanH region - Clostridium perfringens >gi|853809|emb|CAA60798.1| (X87369) ORF3 [Clostridium perfringens]	gene	gene1498	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1834
SPy_1835	SPy1835	trx	trx	1522398	1522712	-	putative thioredoxin	Best Blastp hit %3D dbj|BAB06817.1| (AP001517) thioredoxin [Bacillus halodurans]	gene	gene1499	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1835
SPy_1836	SPy1836		SPy_1836	1522793	1523296	-	hypothetical protein	Best Blastp hit %3D gb|AAC45388.1| (U81488) putative phosphatidic acid phosphatase [Lactococcus lactis subsp. cremoris]	gene	gene1500	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1836
SPy_1837	SPy1837	mutS2	mutS2	1523297	1525636	-	putative DNA mismatch repair protein	Best Blastp hit %3D sp|Q9ZEH5|MUS2_STAAU MUTS2 PROTEIN >gi|3776110|emb|CAA11403.1| (AJ223480) MutS-like protein [Staphylococcus aureus]	gene	gene1501	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1837
SPy_1839	SPy1839		SPy_1839	1525785	1526330	-	hypothetical protein	Best Blastp hit %3D pir||B69985 hypothetical protein yshB - Bacillus subtilis >gi|1770034|emb|CAA99567.1| (Z75208) hypothetical protein [Bacillus subtilis] >gi|2635325|emb|CAB14820.1| (Z99118) yshB [Bacillus subtilis]	gene	gene1502	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1839
SPy_1840	SPy1840		SPy_1840	1526333	1526641	-	hypothetical protei	Best Blastp hit %3D emb|CAB40350.1| (AJ131892) Hyperion protein%2C 419 kD isoform [Gallus gallus]	gene	gene1503	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1840
SPy_1841	SPy1841		SPy_1841	1526798	1527700	+	putative ribonuclease HIII	Best Blastp hit %3D sp|O07874|RNH3_STRPN RIBONUCLEASE HIII (RNASE HIII) >gi|2209339|gb|AAC45437.1| (U93576) ribonuclease HII [Streptococcus pneumoniae]	gene	gene1504	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1841
SPy_1842	SPy1842	spi	spi	1527711	1528304	+	putative signal peptidase I	Best Blastp hit %3D sp|O07344|LEP_STRPN SIGNAL PEPTIDASE I (SPASE I) (LEADER PEPTIDASE I) >gi|2149614|gb|AAB69116.1| (U90721) signal peptidase I [Streptococcus pneumoniae]	gene	gene1505	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1842
SPy_1844	SPy1844		SPy_1844	1528362	1530815	+	putative exodeoxyribonuclease V (alpha subunit)	Best Blastp hit %3D pir||A69979 conjugation transfer protein homolog yrrC - Bacillus subtilis >gi|2635193|emb|CAB14689.1| (Z99117) similar to conjugation transfer protein [Bacillus subtilis] >gi|2635211|emb|CAB14706.1| (Z99118) similar to conjugation transfer protein [Bacillus subtilis]	gene	gene1506	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1844
SPy_1845	SPy1845		SPy_1845	1530906	1531388	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1507	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1845
SPy_1846	SPy1846	dinP	dinP	1531481	1532575	-	putative DNA-damage-inducible protein P	Best Blastp hit %3D gb|AAF95431.1| (AE004300) DNA-damage-inducible protein P [Vibrio cholerae]	gene	gene1508	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1846
SPy_1849	SPy1849	pfl	pfl	1532784	1535111	+	putative pyruvate formate-lyase	Best Blastp hit %3D dbj|BAA28614.1| (AB014686) pyruvate formate-lyase [Streptococcus bovis]	gene	gene1509	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1849
SPy_1850	SPy1850		SPy_1850	1535289	1536239	-	putative esterase	Best Blastp hit %3D emb|CAC16441.1| (AL450165) putative esterase [Streptomyces coelicolor]	gene	gene1510	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1850
SPy_1851	SPy1851		SPy_1851	1536224	1536976	-	putative C3-degrading proteinase	Best Blastp hit %3D emb|CAB87703.1| (AL163815) putative protein [Arabidopsis thaliana]	gene	gene1511	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1851
SPy_1852	SPy1852		SPy_1852	1537283	1538170	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1512	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1852
SPy_1854	SPy1854	glpF.2	glpF.2	1538506	1539453	-	putative glycerol uptake facilitator protein	Best Blastp hit %3D sp|Q9X1E3|GLPF_THEMA PROBABLE GLYCEROL UPTAKE FACILITATOR PROTEIN >gi|7444137|pir||B72254 glycerol uptake facilitator protein - Thermotoga maritima (strain MSB8) >gi|4981994|gb|AAD36499.1|AE001795_2 (AE001795) glycerol uptake facilitator protein [Thermotoga maritima]	gene	gene1513	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1854
SPy_1856	SPy1856	norA	norA	1539856	1541151	-	putative antibiotic resistance protein NorA	Best Blastp hit %3D pir||S74875 quinolone resistance protein norA - Synechocystis sp. (strain PCC 6803) >gi|1652918|dbj|BAA17836.1| (D90909) quinolene resistance protein NorA [Synechocystis sp.]	gene	gene1514	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1856
SPy_1857	SPy1857		SPy_1857	1541158	1541877	+	putative transcriptional regulatory protein	Best Blastp hit %3D emb|CAA65740.1| (X97014) PrfA [Listeria seeligeri]	gene	gene1515	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1857
SPy_1858	SPy1858	pepXP	pepXP	1541899	1544181	+	putative X-Pro dipeptidyl-peptidase IV	Best Blastp hit %3D sp|P22093|PEPX_LACLC XAA-PRO DIPEPTIDYL-PEPTIDASE (X-PRO DIPEPTIDYL-PEPTIDASE) (X-PROLYL-DIPEPTIDYL AMINOPEPTIDASE) (X-PDAP) >gi|280236|pir||A43747 X-Pro dipeptidyl-peptidase (EC 3.4.14.11) - Lactococcus lactis subsp. cremoris >gi|149528|gb|AAA25232.1| (M58315) dipeptidyl peptidase IV [Lactococcus lactis]	gene	gene1516	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1858
SPy_1861	SPy1861		SPy_1861	1544652	1545026	+	putative repressor - phage associated	Best Blastp hit %3D gb|AAC03457.1| (AF020798) repressor [Streptococcus thermophilus bacteriophage TP-J34]	gene	gene1517	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1861
SPy_1862	SPy1862		SPy_1862	1545219	1545518	+	hypothetical protein	Best Blastp hit %3D sp|P24281|YAAK_BACSU HYPOTHETICAL 11.8 KD PROTEIN IN DNAZ-RECR INTERGENIC REGION >gi|98365|pir||S13787 conserved hypothetical protein yaaK - Bacillus subtilis >gi|40073|emb|CAA34878.1| (X17014) ORF107 [Bacillus subtilis] >gi|467410|dbj|BAA05256.1| (D26185) unknown [Bacillus subtilis] >gi|2632287|emb|CAB11796.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1518	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1862
SPy_1863	SPy1863		SPy_1863	1545575	1546312	-	putative transcriptional activator regulator protein	Best Blastp hit %3D dbj|BAB04127.1| (AP001508) transcriptional activator of multidrug-efflux transporter genes [Bacillus halodurans]	gene	gene1519	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1863
SPy_1864	SPy1864	dnaQ	dnaQ	1546461	1547087	-	putative DNA polymerase III epsilon subunit	Best Blastp hit %3D sp|O67074|DP3E_AQUAE DNA POLYMERASE III%2C EPSILON CHAIN >gi|7514775|pir||G70380 DNA polymerase III epsilon subunit - Aquifex aeolicus >gi|2983450|gb|AAC07031.1| (AE000714) DNA polymerase III epsilon subunit [Aquifex aeolicus]	gene	gene1520	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1864
SPy_1865	SPy1865		SPy_1865	1547097	1547678	-	hypothetical protein	Best Blastp hit %3D gi|10956234 unknown [Lactococcus lactis subsp. lactis] >gi|9294802|gb|AAF86680.1| (AF179848) unknown [Lactococcus lactis subsp. lactis]	gene	gene1521	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1865
SPy_1866	SPy1866		SPy_1866	1547833	1549002	+	hypothetical protein	Best Blastp hit %3D gb|AAC00390.1| (AF008220) YtfP [Bacillus subtilis]	gene	gene1522	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1866
SPy_1867	SPy1867	deoC	deoC	1549097	1549768	-	putative deoxyribose-phosphate aldolase	Best Blastp hit %3D pir||D82872 deoxyribose-phosphate aldolase UU585 [imported] - Ureaplasma urealyticum >gi|6899595|gb|AAF30999.1|AE002157_4 (AE002157) deoxyribose-phosphate aldolase [Ureaplasma urealyticum]	gene	gene1523	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1867
SPy_1868	SPy1868	nupC	nupC	1549798	1551000	-	putative nucleoside transporter	Best Blastp hit %3D pir||D82135 NupC family protein VC1953 [imported] - Vibrio cholerae (group O1 strain N16961) >gi|9656492|gb|AAF95101.1| (AE004271) NupC family protein [Vibrio cholerae]	gene	gene1524	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1868
SPy_1869	SPy1869	udp	udp	1551021	1551800	-	putative uridine phosphorylase	Best Blastp hit %3D emb|CAB94934.1| (AJ278525) uridine phosphorylase [Yersinia pseudotuberculosis]	gene	gene1525	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1869
SPy_1870	SPy1870		SPy_1870	1552040	1552783	+	putative transcriptional regulator (GntR family)	Best Blastp hit %3D sp|O31761|YMFC_BACSU HYPOTHETICAL TRANSCRIPTIONAL REGULATOR IN SPOIIIE-PGSA INTERGENIC REGION >gi|7443061|pir||B69885 transcription regulator GntR family homolog ymfC - Bacillus subtilis >gi|2634053|emb|CAB13554.1| (Z99112) similar to transcriptional regulator (GntR family) [Bacillus subtilis]	gene	gene1526	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1870
SPy_1871	SPy1871	rpsN2	rpsN2	1553019	1553288	+	30S ribosomal protein S14	Best Blastp hit %3D sp|O31587|R14B_BACSU 30S RIBOSOMAL PROTEIN S14-2 >gi|7440416|pir||F69835 ribosomal protein S14 homolog yhzA - Bacillus subtilis >gi|2633211|emb|CAB12716.1| (Z99108) similar to ribosomal protein S14 [Bacillus subtilis]	gene	gene1527	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1871
SPy_1872	SPy1872		SPy_1872	1553459	1554487	-	putative glycoprotein endopeptidase	Best Blastp hit %3D sp|O05518|GCP_BACSU PROBABLE O-SIALOGLYCOPROTEIN ENDOPEPTIDASE (GLYCOPROTEASE) >gi|7444711|pir||F69786 glycoprotein endopeptidase homolog ydiE - Bacillus subtilis >gi|1945110|dbj|BAA19718.1| (D88802) P. haemolytica o-sialoglycoprotein endopeptidase%3B P36175 (660) transmembrane [Bacillus subtilis] >gi|2632907|emb|CAB12413.1| (Z99107) similar to glycoprotein endopeptidase [Bacillus subtilis]	gene	gene1528	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1872
SPy_1873	SPy1873		SPy_1873	1554477	1554902	-	putative ribosomal-protein-alanine acetyltransferase	Best Blastp hit %3D gb|AAF93823.1| (AE004151) ribosomal-protein-alanine acetyltransferase [Vibrio cholerae]	gene	gene1529	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1873
SPy_1874	SPy1874		SPy_1874	1554904	1555602	-	putative glycoprotein endopeptidase	Best Blastp hit %3D emb|CAA76861.1| (Y17797) hypothetical protein [Enterococcus faecalis]	gene	gene1530	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1874
SPy_1875	SPy1875		SPy_1875	1555887	1556117	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06380.1| (AP001516) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1531	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1875
SPy_1876	SPy1876		SPy_1876	1556119	1557801	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06381.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene1532	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1876
SPy_1877	SPy1877	glnA	glnA	1558028	1559374	-	putative glutamine synthetase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P19064|GLNA_BACCE GLUTAMINE SYNTHETASE (GLUTAMATE-AMMONIA LIGASE) >gi|68610|pir||AJBSQU glutamate-ammonia ligase (EC 6.3.1.2) - Bacillus cereus >gi|216273|dbj|BAA00403.1| (D00513) glutamine synthetase [Bacillus cereus]	gene	gene1533	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1877
SPy_1878	SPy1878		SPy_1878	1559412	1559783	-	putative transcriptional regulator	Best Blastp hit %3D dbj|BAA00729.1| (D00854) GlnR protein [Bacillus subtilis]	gene	gene1534	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1878
SPy_1879	SPy1879		SPy_1879	1559850	1560401	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1535	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1879
SPy_1881	SPy1881	pgk	pgk	1560664	1561860	-	putative phosphoglycerate kinase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|O32756|PGK_LACDE PHOSPHOGLYCERATE KINASE >gi|7434542|pir||T09634 phosphoglycerate kinase (EC 2.7.2.3) - Lactobacillus delbrueckii >gi|2624192|emb|CAA04015.1| (AJ000339) phosphoglycerate kinase [Lactobacillus delbrueckii]	gene	gene1536	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1881
SPy_1882	SPy1882	lppC	lppC	1562053	1562907	-	putative acid phosphatase	Best Blastp hit %3D emb|CAA73299.1| (Y12759) acid phosphatase [Chryseobacterium meningosepticum]	gene	gene1537	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1882
SPy_1884	SPy1884		SPy_1884	1563137	1564027	-	eukaryotic hypersensitive-induced response-like protein	Best Blastp hit %3D gb|AAF03497.1|AC010676_7 (AC010676) unknown protein [Arabidopsis thaliana] >gi|6714460|gb|AAF26146.1|AC008261_3 (AC008261) unknown protein [Arabidopsis thaliana]	gene	gene1538	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1884
SPy_1885	SPy1885		SPy_1885	1564264	1565928	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06217.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1539	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1885
SPy_1886	SPy1886	asp	asp	1565928	1566293	-	putative alkaline-shock protein	Best Blastp hit %3D dbj|BAB06218.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1540	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1886
SPy_1888	SPy1888	rpmB	rpmB	1566445	1566633	-	50S ribosomal protein L28	Best Blastp hit %3D dbj|BAB06219.1| (AP001515) ribosomal protein L28 [Bacillus halodurans]	gene	gene1541	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1888
SPy_1889	SPy1889	fba	fba	1567015	1567896	-	putative fructose-bisphosphate aldolase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB16889.1| (AB050113) class-II aldolase [Streptococcus bovis]	gene	gene1542	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1889
SPy_1892	SPy1892		SPy_1892	1568242	1569168	-	hypothetical protein	Best Blastp hit %3D pir||D75217 probable 2-acetyl-1-alkylglycerophosph ocholine esterase PAB2176 - Pyrococcus abyssi (strain Orsay) >gi|5457696|emb|CAB49187.1| (AJ248283) hypothetical 2-acetyl-1-alkylglycerophosph ocholine esterase [Pyrococcus abyssi]	gene	gene1544	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1892
SPy_1894	SPy1894	pyrG	pyrG	1569336	1570940	-	putative CTP synthetase	Best Blastp hit %3D sp|P13242|PYRG_BACSU CTP SYNTHASE (UTP-AMMONIA LIGASE) (CTP SYNTHETASE) >gi|68632|pir||SYBSTP CTP synthase (EC 6.3.4.2) - Bacillus subtilis >gi|143597|gb|AAA16801.1| (M22039) CTP synthetase [Bacillus subtilis] >gi|853762|emb|CAA89870.1| (Z49782) CTP synthase [Bacillus subtilis] >gi|2636252|emb|CAB15743.1| (Z99123) CTP synthetase [Bacillus subtilis]	gene	gene1545	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1894
SPy_1895	SPy1895	rpoE	rpoE	1571197	1571772	-	putative DNA-directed RNA polymerase (delta subunit)	Best Blastp hit %3D sp|P12464|RPOE_BACSU DNA-DIRECTED RNA POLYMERASE DELTA SUBUNIT >gi|80262|pir||JT0302 DNA-directed RNA polymerase (EC 2.7.7.6) delta chain rpoE - Bacillus subtilis >gi|143456|gb|AAA22710.1| (M21677) rpoE protein (ttg start codon) [Bacillus subtilis] >gi|853761|emb|CAA89869.1| (Z49782) RNA polymerase delta subunit [Bacillus subtilis] >gi|2636253|emb|CAB15744.1| (Z99123) RNA polymerase (delta subunit) [Bacillus subtilis]	gene	gene1546	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1895
SPy_1896	SPy1896	ropA	ropA	1571989	1573272	-	transcription regulator - (trigger factor (prolyl isomerase))	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAB06772.1| (AP001517) trigger factor (prolyl isomerase) [Bacillus halodurans]	gene	gene1547	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1896
SPy_1897	SPy1897		SPy_1897	1573593	1574438	+	hypothetical protein	Best Blastp hit %3D dbj|BAB06385.1| (AP001516) unknown conserved protein [Bacillus halodurans]	gene	gene1548	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1897
SPy_1898	SPy1898		SPy_1898	1574503	1575060	-	hypothetical protein	Best Blastp hit %3D dbj|BAB07485.1| (AP001519) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1549	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1898
SPy_1899	SPy1899		SPy_1899	1575077	1575547	-	hypothetical protein	Best Blastp hit %3D pir||A71195 hypothetical protein PH1832 - Pyrococcus horikoshii >gi|3258269|dbj|BAA30952.1| (AP000007) 202aa long hypothetical protein [Pyrococcus horikoshii]	gene	gene1550	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1899
SPy_1900	SPy1900	thiD	thiD	1575537	1576301	-	putative phosphomethylpyrimidine kinase	Best Blastp hit %3D sp|O67772|THID_AQUAE PHOSPHOMETHYLPYRIMIDINE KINASE (HMP-PHOSPHATE KINASE) (HMP-P KINASE) >gi|7449914|pir||H70467 HMP-P kinase - Aquifex aeolicus >gi|2984203|gb|AAC07733.1| (AE000765) HMP-P kinase [Aquifex aeolicus]	gene	gene1551	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1900
SPy_1901	SPy1901	truA	truA	1576291	1577040	-	putative tRNA pseudouridine synthase A	Best Blastp hit %3D sp|Q9Z9J0|TRUA_BACHD TRNA PSEUDOURIDINE SYNTHASE A (PSEUDOURIDYLATE SYNTHASE I) (PSEUDOURIDINE SYNTHASE I) (URACIL HYDROLYASE) >gi|11269487|pir||T44415 pseudouridylate synthase I truA [imported] - Bacillus halodurans >gi|4512436|dbj|BAA75303.1| (AB017508) truA homologue (identity of 62%25 to B. subtilis) [Bacillus halodurans] >gi|10172779|dbj|BAB03886.1| (AP001507) tRNA pseudouridine synthase A (pseudouridylate synthase I) [Bacillus halodurans]	gene	gene1552	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1901
SPy_1902	SPy1902	comX1.2	comX1.2	1577225	1577776	-	ComX1-like protein	Best Blastp hit %3D emb|CAA46629.1| (X65713) ORF [Lactococcus lactis]	gene	gene1553	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1902
SPy_1903	SPy1903		SPy_1903	1583503	1584576	-	hypothetical protein	Best Blastp hit %3D sp|P73408|YI40_SYNY3 HYPOTHETICAL 39.2 KDA PROTEIN SLR1840 >gi|7449090|pir||S77345 hypothetical protein slr1840 - Synechocystis sp. (strain PCC 6803) >gi|1652527|dbj|BAA17448.1| (D90906) hypothetical protein [Synechocystis sp.]	gene	gene1559	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1903
SPy_1904	SPy1904	hsdR	hsdR	1584927	1587905	+	putative type I site-specific deoxyribonuclease	Best Blastp hit %3D gi|10956196 type IC restriction subunit [Streptococcus thermophilus] >gi|6137147|gb|AAF04356.1| (AF177167) type IC restriction subunit [Streptococcus thermophilus]	gene	gene1560	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1904
SPy_1905	SPy1905	hsdS	hsdS	1587918	1589117	+	putative type I site-specific deoxyribonuclease	Best Blastp hit %3D gb|AAB53491.1| (U35629) unknown [Lactococcus lactis subsp. lactis]	gene	gene1561	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1905
SPy_1906	SPy1906	hsdM	hsdM	1589130	1590710	+	putative type I site-specific deoxyribonuclease	Best Blastp hit %3D gi|10956197 type IC modification subunit [Streptococcus thermophilus] >gi|11279435|pir||T44803 type I site-specific deoxyribonuclease (EC 3.1.21.3) chain hsdM [imported] - Streptococcus thermophilus plasmid pER35 >gi|6137148|gb|AAF04357.1| (AF177167) type IC modification subunit [Streptococcus thermophilus]	gene	gene1562	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1906
SPy_1908	SPy1908	salR	salR	1591263	1591868	-	putative response regulator of salavaricin regulon	Best Blastp hit %3D sp|P14204|COMA_BACSU COMPETENCE PROTEIN A >gi|72615|pir||RGBSCA regulatory protein comA - Bacillus subtilis >gi|142701|gb|AAA22320.1| (M22856) A competence protein 1 [Bacillus subtilis] >gi|1934772|emb|CAB07904.1| (Z93932) comAA [Bacillus subtilis] >gi|2635663|emb|CAB15156.1| (Z99120) two-component response regulator [Bacillus subtilis] >gi|10119872|dbj|BAB13494.1| (AB039951) ComA respons regulator [Bacillus subtilis]	gene	gene1563	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1908
SPy_1910	SPy1910	salK	salK	1591849	1593410	-		This gene contains a confirmed frameshift mutation%3B Best Blastp hit %3D gi|11245965|gb|AAG32541.1| (AY005472) SalK [Streptococcus salivarius]	gene	gene1564	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1910
SPy_1911	SPy1911	salY	salY	1593450	1595357	-	putative ABC transporter (permease) associated with salivaricin lantibiotic	Best Blastp hit %3D pir||B70001 ABC transporter (permease) homolog ytsD - Bacillus subtilis >gi|2293178|gb|AAC00256.1| (AF008220) YtsD [Bacillus subtilis] >gi|2635521|emb|CAB15015.1| (Z99119) similar to ABC transporter (permease) [Bacillus subtilis]	gene	gene1565	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1911
SPy_1912	SPy1912	salX	salX	1595359	1596096	-	putative salivaricin A ABC transporter (ATP-binding protein)	Best Blastp hit %3D pir||A70001 ABC transporter (ATP-binding protein) homolog ytsC - Bacillus subtilis >gi|2293177|gb|AAC00255.1| (AF008220) transporter [Bacillus subtilis] >gi|2635522|emb|CAB15016.1| (Z99119) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene1566	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1912
SPy_1913	SPy1913		SPy_1913	1596093	1596554	-			gene	gene1567	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1913
SPy_1914	SPy1914	salB	salB	1596628	1598253	-	putative salivaricin A modification enzyme%3B amino acid dehydration	Best Blastp hit %3D pir||C55226 cylM protein - Enterococcus faecalis >gi|559861|gb|AAA62650.1| (L37110) clyM [Plasmid pAD1]	gene	gene1568	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1914
SPy_1915	SPy1915	salA	salA	1598336	1598491	-	lantibiotic precursor	Best Blastp hit %3D gb|AAA02867.2| (AY005472) SalA [Streptococcus salivarius]	gene	gene1569	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1915
SPy_1916	SPy1916	lacG	lacG	1598994	1600400	-	putative phospho-beta-D-galactosidase	Best Blastp hit %3D gb|AAA26949.1| (M19454) phospho-beta-D-galactosidase (EC 3.2.1.85) [Lactococcus lactis subsp. cremoris]	gene	gene1570	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1916
SPy_1917	SPy1917	lacE	lacE	1600488	1602185	-	putative PTS system%2C lactose-specific component IIBC	Best Blastp hit %3D sp|P23531|PTLB_LACLA PTS SYSTEM%2C LACTOSE-SPECIFIC IIBC COMPONENT (EIIBC-LAC) (LACTOSE-PERMEASE IIBC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C BC COMPONENT) (EII-LAC) >gi|97952|pir||B23696 phosphotransferase system enzyme II (EC 2.7.1.69) - Lactococcus lactis >gi|149411|gb|AAA25182.1| (M60447) enzyme III [Lactococcus lactis]	gene	gene1571	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1917
SPy_1918	SPy1918	lacF	lacF	1602185	1602502	-	putative PTS system%2C lactose-specific component IIA	Best Blastp hit %3D sp|P02909|PTLA_STAAU PTS SYSTEM%2C LACTOSE-SPECIFIC IIA COMPONENT (EIIA-LAC) (LACTOSE-PERMEASE IIA COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C A COMPONENT) (EIII-LAC) >gi|153037|gb|AAA26648.1| (J03479) enzyme III-lac (lacF) [Staphylococcus aureus]	gene	gene1572	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1918
SPy_1919	SPy1919	lacD.2	lacD.2	1602526	1603509	-	putative tagatose 1%2C6-diphosphate aldolase	Best Blastp hit %3D sp|P26593|LACD_LACLA TAGATOSE 1%2C6-DIPHOSPHATE ALDOLASE (TAGATOSE-BISPHOSPHATE ALDOLASE) (D-TAGATOSE-1%2C6-BISPHOSPHATE ALDOLASE) >gi|97943|pir||D39778 LacD tagatose-1%2C6-diphosphate aldolase - Lactococcus lactis >gi|149396|gb|AAA25171.1| (M65190) lacD [Lactococcus lactis] >gi|149409|gb|AAA25180.1| (M60447) tagatose 1%2C6-diP aldolase [Lactococcus lactis]	gene	gene1573	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1919
SPy_1921	SPy1921	lacC.2	lacC.2	1603513	1604442	-	putative tagatose 6-phosphate kinase	Best Blastp hit %3D sp|P26421|LACC_STRMU TAGATOSE-6-PHOSPHATE KINASE (PHOSPHOTAGATOKINASE) >gi|322119|pir||E43258 tagatose-6-phosphate kinase - Streptococcus mutans >gi|153675|gb|AAA26906.1| (M80797) tagatose 6-P kinase [Streptococcus mutans]	gene	gene1574	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1921
SPy_1922	SPy1922	lacB.2	lacB.2	1604490	1605005	-	putative galactose-6-phosphate isomerase (B subunit)	Best Blastp hit %3D sp|P23495|LACB_LACLA GALACTOSE-6-PHOSPHATE ISOMERASE LACB SUBUNIT >gi|97930|pir||B39778 galactose-6-phosphate isomerase (EC 5.3.1.-) component LacB - Lactococcus lactis >gi|149394|gb|AAA25169.1| (M65190) lacB [Lactococcus lactis] >gi|149407|gb|AAA25178.1| (M60447) galactose 6-P isomerase [Lactococcus lactis]	gene	gene1575	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1922
SPy_1923	SPy1923	lacA.2	lacA.2	1605040	1605468	-	galactosidase acetyltransferase	Best Blastp hit %3D sp|P26423|LACA_STRMU GALACTOSE-6-PHOSPHATE ISOMERASE LACA SUBUNIT >gi|322117|pir||C43258 galactoside O-acetyltransferase (EC 2.3.1.18) - Streptococcus mutans >gi|153673|gb|AAA26904.1| (M80797) galactosidase acetyltransferase [Streptococcus mutans]	gene	gene1576	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1923
SPy_1924	SPy1924	lacR.2	lacR.2	1605914	1606687	+	putative lactose phosphotransferase system repressor protein	Best Blastp hit %3D gb|AAA25174.1| (M35375) lactose repressor (lacR%3B alt.) [Lactococcus lactis] >gi|149405|gb|AAA25176.1| (M60447) repressor protein [Lactococcus lactis] >gi|149416|gb|AAA25186.1| (M60673) lacR [Lactococcus lactis]	gene	gene1577	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1924
SPy_1926	SPy1926		SPy_1926	1607343	1607630	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1578	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1926
SPy_1927	SPy1927		SPy_1927	1607620	1607955	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1579	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1927
SPy_1930	SPy1930		SPy_1930	1608022	1609060	+		This orf contains several confirmed frame shifts within the coding region%3B Best Blastp hit %3D emb|CAB96616.1| (AJ400629) integrase [Streptococcus pneumoniae bacteriophage MM1]	gene	gene1580	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1930
SPy_1931	SPy1931	rpsI	rpsI	1609180	1609572	-	ribosomal protein S9	Best Blastp hit %3D sp|P21470|RS9_BACSU 30S RIBOSOMAL PROTEIN S9 (BS10) >gi|7440271|pir||H69699 ribosomal protein S9 (rpsI) - Bacillus subtilis >gi|1644208|dbj|BAA10989.1| (D64126) ribosomal protein S9 [Bacillus subtilis] >gi|2632417|emb|CAB11926.1| (Z99104) ribosomal protein S9 [Bacillus subtilis]	gene	gene1581	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1931
SPy_1932	SPy1932	rplM	rplM	1609593	1610039	-	50S ribosomal protein L13	Best Blastp hit %3D dbj|BAB03887.1| (AP001507) ribosomal protein L13 [Bacillus halodurans]	gene	gene1582	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1932
SPy_1934	SPy1934		SPy_1934	1610257	1610463	-	putative transcription regulator	Best Blastp hit %3D pir||A64334 hypothetical protein MJ0272 - Methanococcus jannaschii >gi|1590997|gb|AAB98257.1| (U67482) repressor protein%2C putative (yorfE) [Methanococcus jannaschii]	gene	gene1583	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1934
SPy_1935	SPy1935		SPy_1935	1610460	1610999	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1584	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1935
SPy_1936	SPy1936		SPy_1936	1611102	1611962	-	hypothetical protein	Best Blastp hit %3D pir||E72246 conserved hypothetical protein - Thermotoga maritima (strain MSB8) >gi|4982034|gb|AAD36536.1|AE001798_1 (AE001798) conserved hypothetical protein [Thermotoga maritima]	gene	gene1585	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1936
SPy_1937	SPy1937		SPy_1937	1612059	1612577	-	hypothetical protein	Best Blastp hit %3D dbj|BAB03833.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene1586	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1937
SPy_1938	SPy1938		SPy_1938	1612581	1613327	-	putative tRNA/rRNA methyltransferase	Best Blastp hit %3D dbj|BAB03832.1| (AP001507) tRNA/rRNA methyltransferase [Bacillus halodurans]	gene	gene1587	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1938
SPy_1939	SPy1939		SPy_1939	1613374	1614171	-	hypothetical protein	Best Blastp hit %3D gi|6323990 Yrf1-6p [Saccharomyces cerevisiae] >gi|1730660|sp|P53819|YN79_YEAST HYPOTHETICAL 211.1 KDA PROTEIN IN COS1 5'REGION >gi|2132793|pir||S63325 probable membrane protein YNL339c - yeast (Saccharomyces cerevisiae) >gi|2258153|emb|CAA96276.1| (Z71615) there is a second Y' element in the left%3B subtelomeric region of chromosome XIV%3B ORF YNL339c [Saccharomyces cerevisiae]	gene	gene1588	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1939
SPy_1940	SPy1940		SPy_1940	1614367	1614780	-	hypothetical protein	Best Blastp hit %3D pir||C69742 conserved hypothetical protein yazC - Bacillus subtilis >gi|2632362|emb|CAB11871.1| (Z99104) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1589	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1940
SPy_1941	SPy1941	cysS	cysS	1614773	1616116	-	putative cysteinyl-tRNA synthetase	Best Blastp hit %3D dbj|BAB03830.1| (AP001507) cysteinyl-tRNA synthetase [Bacillus halodurans]	gene	gene1590	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1941
SPy_1942	SPy1942		SPy_1942	1616144	1616374	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1591	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1942
SPy_1944	SPy1944	cysE	cysE	1616853	1617434	-	putative serine acetyltransferase	Best Blastp hit %3D gb|AAC33374.1| (AF001780) NifP [Cyanothece PCC8801]	gene	gene1592	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1944
SPy_1945	SPy1945		SPy_1945	1617443	1618195	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1593	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1945
SPy_1946	SPy1946	pnpA	pnpA	1618188	1620320	-	putative polynucleotide phosphorylase%2C alpha chain	Best Blastp hit %3D dbj|BAB06126.1| (AP001515) polynucleotide phosphorylase [Bacillus halodurans]	gene	gene1594	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1946
SPy_1947	SPy1947		SPy_1947	1620601	1621332	-	putative transaldolase	Best Blastp hit %3D pir||G72394 transaldolase-related protein - Thermotoga maritima (strain MSB8) >gi|4980794|gb|AAD35383.1|AE001711_6 (AE001711) transaldolase-related protein [Thermotoga maritima]	gene	gene1595	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1947
SPy_1949	SPy1949		SPy_1949	1621485	1622720	-	hypothetical protein	Best Blastp hit %3D dbj|BAB03942.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene1596	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1949
SPy_1950	SPy1950		SPy_1950	1622747	1623031	-	hypothetical protein	Best Blastp hit %3D sp|P39302|PTXB_ECOLI UNKNOWN PENTITOL PHOSPHOTRANSFERASE ENZYME II%2C B COMPONENT >gi|1361123|pir||S56419 hypothetical 10.9K protein (aidB-rpsF intergenic region) - Escherichia coli >gi|537035|gb|AAA97090.1| (U14003) ORF_o101 [Escherichia coli] >gi|1790638|gb|AAC77151.1| (AE000491) orf%2C hypothetical protein [Escherichia coli]	gene	gene1597	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1950
SPy_1952	SPy1952		SPy_1952	1623024	1625084	-	hypothetical protein	Best Blastp hit %3D dbj|BAB03939.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene1598	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1952
SPy_1955	SPy1955	rpsO	rpsO	1625436	1625705	-	30S ribosomal protein S15	Best Blastp hit %3D dbj|BAB06127.1| (AP001515) ribosomal protein S15 (BS18) [Bacillus halodurans]	gene	gene1599	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1955
SPy_1956	SPy1956		SPy_1956	1625863	1626018	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1600	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1956
SPy_1957	SPy1957		SPy_1957	1626144	1626413	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1601	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1957
SPy_1958	SPy1958	def	def	1626514	1627128	+	putative polypeptide deformylase	Best Blastp hit %3D emb|CAC15392.1| (AJ278785) polypeptide deformylase [Streptococcus pneumoniae]	gene	gene1602	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1958
SPy_1959	SPy1959		SPy_1959	1627162	1627704	-	hypothetical protein	Best Blastp hit %3D pir||G70648 hypothetical protein Rv3054c - Mycobacterium tuberculosis (strain H37RV) >gi|1781160|emb|CAB06242.1| (Z83866) hypothetical protein Rv3054c [Mycobacterium tuberculosis]	gene	gene1603	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1959
SPy_1960	SPy1960		SPy_1960	1627835	1628263	-	putative transcriptional regulator (MarR family)	Best Blastp hit %3D pir||G69867 transcription regulator MarR family homolog ykvE - Bacillus subtilis >gi|2633738|emb|CAB13240.1| (Z99111) similar to transcriptional regulator (MarR family) [Bacillus subtilis]	gene	gene1604	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1960
SPy_1961	SPy1961	polC	polC	1628373	1632770	-	DNA polymerase III (alpha subunit)	Best Blastp hit %3D sp|P13267|DPO3_BACSU DNA POLYMERASE III%2C ALPHA CHAIN POLC-TYPE (POLIII) >gi|7447208|pir||F69680 DNA-directed DNA polymerase (EC 2.7.7.7) III alpha chain (polC) - Bacillus subtilis >gi|40060|emb|CAA36362.1| (X52116) DNA polymerase III (AA 1-1437) [Bacillus subtilis] >gi|2634030|emb|CAB13531.1| (Z99112) DNA polymerase III (alpha subunit) [Bacillus subtilis]	gene	gene1605	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1961
SPy_1962	SPy1962	proS	proS	1633025	1634881	-	putative prolyl-tRNA synthetase	Best Blastp hit %3D dbj|BAB06138.1| (AP001515) prolyl-tRNA synthetase [Bacillus halodurans]	gene	gene1606	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1962
SPy_1963	SPy1963		SPy_1963	1635079	1636338	-	may be involved in production of a peptide sex pheromone	Best Blastp hit %3D pir||C69881 conserved hypothetical protein yluC - Bacillus subtilis >gi|2634028|emb|CAB13529.1| (Z99112) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1607	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1963
SPy_1964	SPy1964	cdsA	cdsA	1636411	1637205	-	putative phosphatidate cytidylyltransferase (CDP-diglyceride synthase)	Best Blastp hit %3D sp|O31752|CDSA_BACSU PHOSPHATIDATE CYTIDYLYLTRANSFERASE (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE) >gi|7434900|pir||G69597 phosphatidate cytidylyltransferase cdsA - Bacillus subtilis >gi|2634026|emb|CAB13527.1| (Z99112) phosphatidate cytidylyltransferase (CDP-diglyceride synthase) [Bacillus subtilis]	gene	gene1608	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1964
SPy_1965	SPy1965	uppS	uppS	1637218	1637967	-	putative undecaprenyl pyrophosphate synthetase	Best Blastp hit %3D dbj|BAB06142.1| (AP001515) undecaprenyl pyrophosphate synthetase [Bacillus halodurans]	gene	gene1609	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1965
SPy_1968	SPy1968		SPy_1968	1638186	1638551	-	hypothetical protein	Best Blastp hit %3D sp|O32052|YRBF_BACSU HYPOTHETICAL 9.9 KDA PROTEIN IN SPOVB-TGT INTERGENIC REGION >gi|7444773|pir||E69972 conserved hypothetical protein yrbF - Bacillus subtilis >gi|2635235|emb|CAB14730.1| (Z99118) similar to hypothetical proteins [Bacillus subtilis] >gi|6977809|emb|CAB75334.1| (Y15896) hypothetical protein [Bacillus subtilis]	gene	gene1610	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1968
SPy_1971	SPy1971		SPy_1971	1638667	1639041	-	hypothetical protein	Best Blastp hit %3D gb|AAG28765.1|AF300457_3 (AF300457) CoaC [Bacillus coagulans]	gene	gene1611	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1971
SPy_1972	SPy1972	pulA	pulA	1639156	1642653	-	putative pullulanase	Best Blastp hit %3D dbj|BAB07416.1| (AP001519) alkaline amylopullulanase [Bacillus halodurans]	gene	gene1612	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1972
SPy_1973	SPy1973	dexB	dexB	1642851	1644464	-	dextran glucosidase	Best Blastp hit %3D sp|Q99040|DEXB_STRMU GLUCAN 1%2C6-ALPHA-GLUCOSIDASE (DEXTRAN GLUCOSIDASE) (EXO-1%2C6-ALPHA-GLUCOSIDASE) (GLUCODEXTRANASE) >gi|97985|pir||A37231 glucan 1%2C6-alpha-glucosidase (EC 3.2.1.70) - Streptococcus mutans >gi|153742|gb|AAA26939.1| (M77351) dextran glucosidase [Streptococcus mutans]	gene	gene1613	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1973
SPy_1976	SPy1976	msmK	msmK	1644593	1645726	-	multiple sugar-binding ABC transport system (ATP-binding protein)	Best Blastp hit %3D sp|P94360|MSMX_BACSU PROBABLE MULTIPLE SUGAR-BINDING TRANSPORT ATP-BINDING PROTEIN MSMX >gi|7442505|pir||B69661 multiple sugar-binding transport ATP-binding protein msmX - Bacillus subtilis >gi|1783246|dbj|BAA11723.1| (D83026) highly homologous to many ATP-binding transport proteins%3B hypothetical [Bacillus subtilis] >gi|2636416|emb|CAB15907.1| (Z99123) multiple sugar-binding transport ATP-binding protein [Bacillus subtilis]	gene	gene1614	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1976
SPy_1978	SPy1978	lrp	lrp	1646024	1646872	-	leucine-rich protein	Best Blastp hit %3D pir||H70080 conserved hypothetical protein yxkF - Bacillus subtilis >gi|1783245|dbj|BAA11722.1| (D83026) homologous to leucine rich protein (pir:s39972)%3B hypothetical [Bacillus subtilis] >gi|2636417|emb|CAB15908.1| (Z99123) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1615	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1978
SPy_1979	SPy1979	ska	ska	1647232	1648554	+	streptokinase A precursor	Best Blastp hit %3D sp|P10520|STRP_STRPY STREPTOKINASE A PRECURSOR >gi|80048|pir||S02724 streptokinase A precursor - Streptococcus pyogenes (strain SF130/13) >gi|47436|emb|CAA31765.1| (X13399) streptokinase (AA 1 - 440) [Streptococcus pyogenes]	gene	gene1616	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1979
SPy_1980	SPy1980		SPy_1980	1648652	1649095	-	hypothetical protein	Best Blastp hit %3D gb|AAF82117.1|AF276071_1 (AF276071) conserved hypothetical protein [Thermus aquaticus]	gene	gene1617	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1980
SPy_1981	SPy1981	relA	relA	1649110	1651341	-	(p)ppGpp synthetase	Best Blastp hit %3D gb|AAC46041.1| (U86377) (p)ppGpp synthetase [Bacillus subtilis]	gene	gene1618	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1981
SPy_1983	SPy1983	scl	scl	1651581	1652627	-	collagen-like surface protei	Best Blastp hit %3D gb|AAG30210.1|AF296330_1 (AF296330) collagen-like surface protein [Streptococcus pyogenes]	gene	gene1619	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1983
SPy_1984	SPy1984		SPy_1984	1653009	1653491	+	putative ribonucleotide reductase (NrdI protein)	Best Blastp hit %3D emb|CAB70606.1| (Y18363) ribonucleotide reductase-like (Nrd-like) protein [Streptococcus dysgalactiae subsp. equisimilis]	gene	gene1620	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1984
SPy_1985	SPy1985		SPy_1985	1653885	1654703	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1621	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1985
SPy_1986	SPy1986		SPy_1986	1654786	1656972	-	putative PTS system%2C enzyme II%2C A component	Best Blastp hit %3D dbj|BAB04563.1| (AP001510) PTS system%2C glucose-specific enzyme II%2C A component [Bacillus halodurans]	gene	gene1622	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1986
SPy_1987	SPy1987		SPy_1987	1657330	1658079	-	hypothetical protein	Best Blastp hit %3D dbj|BAB05069.1| (AP001511) unknown conserved protein [Bacillus halodurans]	gene	gene1623	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1987
SPy_1988	SPy1988		SPy_1988	1658079	1659032	-	putative methyltransferase	Best Blastp hit %3D dbj|BAB05068.1| (AP001511) methyltransferase [Bacillus halodurans]	gene	gene1624	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1988
SPy_1989	SPy1989		SPy_1989	1659103	1659534	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1625	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1989
SPy_1990	SPy1990	pabB	pabB	1659773	1661530	+	putative para-aminobenzoate synthetase	Best Blastp hit %3D pir||A71951 p-aminobenzoate synthetase - Helicobacter pylori (strain J99) >gi|4154803|gb|AAD05859.1| (AE001465) P-AMINOBENZOATE SYNTHETASE [Helicobacter pylori J99]	gene	gene1626	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1990
SPy_1991	SPy1991	trpG	trpG	1661563	1662129	+	anthranilate synthase component II	Best Blastp hit %3D sp|Q02003|TRPG_LACLA ANTHRANILATE SYNTHASE COMPONENT II (GLUTAMINE AMIDO-TRANSFERASE) >gi|421418|pir||S35125 anthranilate synthase (EC 4.1.3.27) beta chain - Lactococcus lactis subsp. lactis >gi|551880|gb|AAA25224.1| (M87483) anthranilate synthase beta subunit [Lactococcus lactis]	gene	gene1627	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1991
SPy_1992	SPy1992		SPy_1992	1662162	1663430	+	hypothetical protein	Best Blastp hit %3D pir||D69981 conserved hypothetical protein yrvN - Bacillus subtilis >gi|2635199|emb|CAB14695.1| (Z99117) similar to hypothetical proteins [Bacillus subtilis] >gi|2635217|emb|CAB14712.1| (Z99118) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1628	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1992
SPy_1994	SPy1994		SPy_1994	1663927	1664367	+	pai1 protein (theoretical repressor)	Best Blastp hit %3D gb|AAF08324.1|U78969_1 (U78969) pail repressor [Streptococcus pyogenes]	gene	gene1630	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1994
SPy_1995	SPy1995	flaR	flaR	1664422	1664928	+	topology modulator	Best Blastp hit %3D gb|AAF08325.1|U78969_2 (U78969) FlaR [Streptococcus pyogenes]	gene	gene1631	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1995
SPy_1998	SPy1998	smeZ	smeZ	1665177	1665878	+	mitogenic exotoxin Z	Best Blastp hit %3D gb|AAF66665.1|AF143665_1 (AF143665) mitogenic exotoxin Z-15 [Streptococcus pyogenes]	gene	gene1632	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1998
SPy_1999	SPy1999		SPy_1999	1666162	1666428	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1633	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_1999
SPy_2000	SPy2000	dppA	dppA	1666607	1668235	+	surface lipoprotein	Best Blastp hit %3D gb|AAC67217.1| (U78968) surface lipoprotein DppA [Streptococcus pyogenes]	gene	gene1634	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2000
SPy_2001	SPy2001	dppB	dppB	1668348	1669325	+	transmembrane transport protein	Best Blastp hit %3D gb|AAC67218.1| (U78968) transmembrane transport protein DppB [Streptococcus pyogenes]	gene	gene1635	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2001
SPy_2002	SPy2002	dppC	dppC	1669322	1670143	+	transmembrane transport protein	Best Blastp hit %3D gb|AAC67219.1| (U78968) transmembrane transport protein DppC [Streptococcus pyogenes]	gene	gene1636	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2002
SPy_2003	SPy2003	dppD	dppD	1670155	1670958	+	ATPase protein	Best Blastp hit %3D gb|AAC67220.1| (U78968) ATPase protein DppD [Streptococcus pyogenes]	gene	gene1637	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2003
SPy_2004	SPy2004	dppE	dppE	1670942	1671568	+	ATPase protein	Best Blastp hit %3D gb|AAC67221.1| (U78968) ATPase protein DppE [Streptococcus pyogenes]	gene	gene1638	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2004
SPy_2005	SPy2005		SPy_2005	1671649	1671849	-	hypothetical protein	Best Blastp hit %3D emb|CAB61195.1| (AL132973) hypothetical protein SCF91.38c. [Streptomyces coelicolor A3(2)]	gene	gene1639	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2005
SPy_2006	SPy2006		SPy_2006	1672018	1674495	-	hypothetical protein	Best Blastp hit %3D gb|AAB58414.1| (AF000561) TTF-I interacting peptide 21%3B TIP21%3B Transcription Termination Factor I Interacting Peptide 21 [Homo sapiens]	gene	gene1640	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2006
SPy_2007	SPy2007	lmb	lmb	1674508	1675428	-	putative laminin adhesion	Best Blastp hit %3D emb|CAA56617.1| (X80397) orf2 [Streptococcus pyogenes]	gene	gene1641	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2007
SPy_2009	SPy2009		SPy_2009	1675664	1676803	-	hypothetical protein	Best Blastp hit %3D emb|CAA56616.1| (X80397) orf1 [Streptococcus pyogenes]	gene	gene1642	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2009
SPy_2010	SPy2010	scpA	scpA	1676900	1680445	-	C5A peptidase precursor	Best Blastp hit %3D gb|AAB17762.1| (U56908) SCPB [Streptococcus agalactiae]	gene	gene1643	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2010
SPy_2013	SPy2013		SPy_2013	1680879	1682084	+	transposase - IS1562	Best Blastp hit %3D gb|AAC38767.1| (AF064540) putative transposase [Streptococcus pyogenes]	gene	gene1644	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2013
SPy_2016	SPy2016	sic	sic	1682663	1683589	-	inhibitor of complement-mediated lysis	Best Blastp hit %3D gb|AAF64820.1|AF232356_1 (AF232356) Sic1.51 [Streptococcus pyogenes]	gene	gene1645	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2016
SPy_2018	SPy2018	emm1	emm1	1683778	1685232	-	M protein type 1	Best Blastp hit %3D pir||S35401 M1 protein precursor - Streptococcus pyogenes >gi|311758|emb|CAA44062.1| (X62131) M protein type 1 [Streptococcus pyogenes]	gene	gene1646	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2018
SPy_2019	SPy2019	mga	mga	1685417	1687006	-	M protein trans-acting positive regulator	Best Blastp hit %3D pir||A42730 trans-acting positive regulator Mry - Streptococcus pyogenes (type M6%2C strain D471)	gene	gene1647	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2019
SPy_2023	SPy2023		SPy_2023	1687682	1687933	-	hypothetical protein (mga-associated)	Best Blastp hit %3D dbj|BAA36701.2| (AB016537) ORF [Streptococcus pyogenes]	gene	gene1648	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2023
SPy_2025	SPy2025	isp	isp	1688012	1689637	-	immunogenic secreted protein precursor	Best Blastp hit %3D emb|CAB70620.1| (AJ243106) transfer protein [Streptococcus thermophilus]	gene	gene1649	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2025
SPy_2026	SPy2026		SPy_2026	1689739	1691127	-	putative histidine kinase	Best Blastp hit %3D emb|CAB54575.1| (AJ006395) histidine kinase [Streptococcus pneumoniae]	gene	gene1650	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2026
SPy_2027	SPy2027		SPy_2027	1691124	1691777	-	putative two-component response regulator	Best Blastp hit %3D sp|Q47744|VANR_ENTFA REGULATORY PROTEIN VANRB >gi|1209526|gb|AAB05622.1| (U35369) response regulator [Enterococcus faecalis]	gene	gene1651	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2027
SPy_2029	SPy2029		SPy_2029	1691871	1693088	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P46324|YVRN_BACSU HYPOTHETICAL 45.1 KDA PROTEIN IN GERAC-FHUC INTERGENIC REGION >gi|2832801|emb|CAA11725.1| (AJ223978) YvrN protein [Bacillus subtilis]	gene	gene1652	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2029
SPy_2031	SPy2031		SPy_2031	1693101	1693775	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB07392.1| (AP001519) ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1653	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2031
SPy_2032	SPy2032		SPy_2032	1693762	1695030	-	putative ATP-binding cassette transporter-like protein	Best Blastp hit %3D pir||B70048 conserved hypothetical protein yvrP - Bacillus subtilis >gi|2635826|emb|CAB15319.1| (Z99120) similar to hypothetical proteins from B. subtilis [Bacillus subtilis] >gi|2635842|emb|CAB15334.1| (Z99121) similar to hypothetical proteins from B. subtilis [Bacillus subtilis] >gi|2832799|emb|CAA11723.1| (AJ223978) YvrP protein [Bacillus subtilis]	gene	gene1654	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2032
SPy_2033	SPy2033		SPy_2033	1695453	1695857	-	hypothetical protein	Best Blastp hit %3D pir||T27702 hypothetical protein ZK1151.3 - Caenorhabditis elegans >gi|3881532|emb|CAB07723.1| (Z93398) cDNA EST yk4e8.3 comes from this gene~cDNA EST yk4e8.5 comes from this gene~cDNA EST EMBL:T00673 comes from this gene~cDNA EST yk20d2.5 comes from this gene~cDNA EST yk23g8.5 comes from this gene~cDNA EST yk37e2.5 comes from this gene~cDNA EST>	gene	gene1655	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2033
SPy_2034	SPy2034		SPy_2034	1695884	1696180	-	conversed hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1656	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2034
SPy_2037	SPy2037		SPy_2037	1696936	1697865	-	hypothetical protein	Best Blastp hit %3D sp|P15294|PRTM_LACLA PROTEASE MATURATION PROTEIN PRECURSOR >gi|79978|pir||S08083 probable protein export protein prtM precursor - Lactococcus lactis subsp. cremoris (strain NCDO 763) plasmid pLP763 >gi|47198|emb|CAA32349.1| (X14130) ORF (AA 1 to 299) [Lactococcus lactis subsp. cremoris]	gene	gene1657	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2037
SPy_2038	SPy2038		SPy_2038	1698345	1698650	-			gene	gene1658	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2038
SPy_2039	SPy2039	speB	speB	1698652	1699848	-	pyrogenic exotoxin B	Best Blastp hit %3D gb|AAA26982.1| (L26153) pyrogenic exotoxin B [Streptococcus pyogenes] >gi|431624|gb|AAA26984.1| (L26155) pyrogenic exotoxin B [Streptococcus pyogenes] >gi|431650|gb|AAA26997.1| (L26131) pyrogenic exotoxin B [Streptococcus pyogenes] >gi|431664|gb|AAA27004.1| (L26138) pyrogenic exotoxin B [Streptococcus pyogenes] >gi|431688|gb|AAA27016.1| (L26150) pyrogenic exotoxin B [Streptococcus pyogenes]	gene	gene1659	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2039
SPy_2040	SPy2040		SPy_2040	1700120	1700290	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1660	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2040
SPy_2041	SPy2041		SPy_2041	1700374	1700505	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1661	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2041
SPy_2042	SPy2042	ropB	ropB	1700789	1701631	+	putative transcription regulator	Best Blastp hit %3D dbj|BAB16026.1| (AB030578) RopB [Streptococcus pyogenes]	gene	gene1662	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2042
SPy_2043	SPy2043	mf	mf	1701872	1702687	-	mitogenic factor	Best Blastp hit %3D emb|CAA59264.1| (X84793) streptodornase [Streptococcus pyogenes]	gene	gene1663	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2043
SPy_2045	SPy2045		SPy_2045	1703051	1703560	+	protein low temperature requirement C	Best Blastp hit %3D sp|O32124|YUTG_BACSU HYPOTHETICAL 18.7 KDA PROTEIN IN HOM-MRGA INTERGENIC REGION >gi|7474749|pir||A70024 conserved hypothetical protein yutG - Bacillus subtilis >gi|2635725|emb|CAB15218.1| (Z99120) similar to hypothetical proteins from B. subtilis [Bacillus subtilis]	gene	gene1664	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2045
SPy_2047	SPy2047	gldA	gldA	1703642	1704730	-	putative glycerol dehydrogenase	Best Blastp hit %3D sp|P45511|GLDA_CITFR GLYCEROL DEHYDROGENASE (GLDH) >gi|493084|gb|AAB48844.1| (U09771) glycerol dehydrogenase [Citrobacter freundii]	gene	gene1665	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2047
SPy_2048	SPy2048	mipB	mipB	1704787	1705455	-	putative transaldolase-like protein	Best Blastp hit %3D sp|P78055|MIPB_ECOLI TRANSALDOLASE-LIKE PROTEIN MIPB >gi|1651205|dbj|BAA13552.1| (D88188) MipB [Escherichia coli]	gene	gene1666	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2048
SPy_2049	SPy2049	pflD	pflD	1705468	1707885	-	putative pyruvate formate-lyase 2	Best Blastp hit %3D dbj|BAA35504.1| (D90719) Formate acetyltransferase 2 (EC 2.3.1.54) (pyruvate formate-lyase 2). [Escherichia coli]	gene	gene1667	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2049
SPy_2050	SPy2050		SPy_2050	1708095	1709399	-	putative PTS system%2C enzyme IIC component	Best Blastp hit %3D sp|P46317|PTCC_BACSU PTS SYSTEM%2C CELLOBIOSE-SPECIFIC IIC COMPONENT (EIIC-CEL) (CELLOBIOSE-PERMEASE IIC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C C COMPONENT) >gi|1361402|pir||S57760 probable cellobiose phosphotransferase enzyme II'' - Bacillus subtilis >gi|7449991|pir||F69651 PTS lichenan-specific enzyme IIC component licC - Bacillus subtilis >gi|895749|emb|CAA90286.1| (Z49992) putative cellobiose phosphotransferase enzyme II'' [Bacillus subtilis] >gi|1783267|dbj|BAA11744.1| (D83026) cellobiose phosphotransferase enzyme II'' [Bacillus subtilis] >gi|2636393|emb|CAB15884.1| (Z99123) phosphotransferase system (PTS) lichenan-specific enzyme IIC component [Bacillus subtilis]	gene	gene1668	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2050
SPy_2051	SPy2051		SPy_2051	1709409	1709717	-	putative PTS system%2C enzyme IIB	Best Blastp hit %3D sp|Q45399|PTCB_BACST PTS SYSTEM%2C CELLOBIOSE-SPECIFIC IIB COMPONENT (EIIB-CEL) (CELLOBIOSE-PERMEASE IIB COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C B COMPONENT) >gi|541382|pir||B49898 cellobiose phosphotransferase system celA - Bacillus stearothermophilus >gi|466473|gb|AAA17389.1| (U07818) cellobiose phosphotransferase enzyme II' [Bacillus stearothermophilus]	gene	gene1669	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2051
SPy_2052	SPy2052		SPy_2052	1709745	1710065	-	putative PTS system%2C enzyme III	Best Blastp hit %3D gb|AAA23551.1| (M93570) PTS enzyme III cel [Escherichia coli]	gene	gene1670	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2052
SPy_2053	SPy2053		SPy_2053	1710353	1711333	-	putative transcriptional regulator	Best Blastp hit %3D dbj|BAB04499.1| (AP001509) transcriptional regulator [Bacillus halodurans]	gene	gene1671	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2053
SPy_2054	SPy2054		SPy_2054	1711349	1712095	-	putative transcriptional regulator	Best Blastp hit %3D sp|P44780|FUCR_HAEIN L-FUCOSE OPERON ACTIVATOR >gi|1074952|pir||G64081 fuc operon regulatory protein homolog - Haemophilus influenzae (strain Rd KW20) >gi|1573609|gb|AAC22274.1| (U32744) L-fucose operon activator (fucR) [Haemophilus influenzae Rd]	gene	gene1672	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2054
SPy_2055	SPy2055		SPy_2055	1712221	1712994	+	putative pyruvate formate-lyase activating enzyme	Best Blastp hit %3D pir||A69431 probable pyruvate formate-lyase activating enzyme (EC 1.97.1.4) pflC homolog - Archaeoglobus fulgidus >gi|2649121|gb|AAB89799.1| (AE001003) pyruvate formate-lyase 2 activating enzyme (pflC) [Archaeoglobus fulgidus]	gene	gene1673	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2055
SPy_2058	SPy2058		SPy_2058	1713231	1713407	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1674	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2058
SPy_2059	SPy2059	pbp2A	pbp2A	1713622	1715958	-	penicillin-binding protein 2a	Best Blastp hit %3D emb|CAA05303.1| (AJ002292) penicillin-binding protein 2a [Streptococcus pneumoniae]	gene	gene1675	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2059
SPy_2060	SPy2060		SPy_2060	1715997	1716377	-	hypothetical protein	Best Blastp hit %3D sp|O25598|Y944_HELPY HYPOTHETICAL PROTEIN HP0944 >gi|7429318|pir||H64637 probable translation initiation inhibitor - Helicobacter pylori (strain 26695) >gi|2314082|gb|AAD07989.1| (AE000603) conserved hypothetical protein [Helicobacter pylori 26695]	gene	gene1676	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2060
SPy_2063	SPy2063		SPy_2063	1717136	1717954	+	hypothetical protein	Best Blastp hit %3D sp|P54604|YHCT_BACSU HYPOTHETICAL 33.7 KD PROTEIN IN CSPB-GLPP INTERGENIC REGION >gi|7449278|pir||H69823 conserved hypothetical protein yhcT - Bacillus subtilis >gi|1239996|emb|CAA65704.1| (X96983) hypothetical protein [Bacillus subtilis] >gi|2633244|emb|CAB12749.1| (Z99108) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1677	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2063
SPy_2065	SPy2065		SPy_2065	1718043	1719767	-	hypothetical protein	Best Blastp hit %3D prf||2109195A chondroitin ABC lyase [Proteus vulgaris]	gene	gene1678	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2065
SPy_2066	SPy2066		SPy_2066	1719930	1721426	+	putative dipeptidase	Best Blastp hit %3D emb|CAA66893.1| (X98238) putative%3B orf1 [Lactobacillus sakei]	gene	gene1679	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2066
SPy_2070	SPy2070	groEL	groEL	1722629	1724260	-	heat shock protein (chaperonin)	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAA61520.1| (X89236) heat shock protein [Streptococcus pyogenes]	gene	gene1680	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2070
SPy_2072	SPy2072	groES	groES	1724296	1724586	-	heat shock protein - cochaperonin	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D gb|AAF75592.1|AF214488_2 (AF214488) GroES [Lactobacillus johnsonii]	gene	gene1681	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2072
SPy_2073	SPy2073	clpC	clpC	1724764	1727208	-	putative endopeptidase Clp ATP-binding chain C	Best Blastp hit %3D gb|AAC44446.1| (U40604) ClpC ATPase [Listeria monocytogenes]	gene	gene1682	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2073
SPy_2074	SPy2074	ctsR	ctsR	1727208	1727669	-	putative transcriptional regulator	Best Blastp hit %3D sp|P37568|CTSR_BACSU TRANSCRIPTIONAL REGULATOR CTSR >gi|2127052|pir||S66112 transcription repressor ctsR - Bacillus subtilis >gi|467471|dbj|BAA05317.1| (D26185) unknown [Bacillus subtilis] >gi|2632350|emb|CAB11859.1| (Z99104) transcriptional regulator [Bacillus subtilis]	gene	gene1683	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2074
SPy_2077	SPy2077	csp	csp	1727865	1728068	-	putative cold shock protein	Best Blastp hit %3D emb|CAA76697.1| (Y17216) cold shock protein D [Lactococcus lactis]	gene	gene1684	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2077
SPy_2079	SPy2079	ahpC	ahpC	1729064	1729624	+	putative alkyl hydroperoxidase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAA25695.1| (AB010712) alkyl hydroperoxidase [Streptococcus mutans]	gene	gene1686	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2079
SPy_2080	SPy2080	nox1	nox1	1729645	1731177	+	putative NADH oxidase/alkyl hydroperoxidase reductase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D dbj|BAA25696.1| (AB010712) NADH oxidase/alkyl hydroperoxidase reductase [Streptococcus mutans]	gene	gene1687	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2080
SPy_2081	SPy2081	hutI	hutI	1731235	1732521	-	putative imidazolonepropionase (imidazolone-5-propionate hydrolase)	Best Blastp hit %3D dbj|BAB05703.1| (AP001513) imidazolonepropionase (imidazolone-5-propionate hydrolase) [Bacillus halodurans]	gene	gene1688	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2081
SPy_2082	SPy2082	hutU	hutU	1732792	1734822	+	putative urocanate hydratase	Best Blastp hit %3D emb|CAB61139.1| (AL132952) predicted using Genefinder~contains similarity to Pfam domain: PF01175 (Urocanase)%2C Score%3D350.6%2C E-value%3D5.7e-102%2C N%3D1~cDNA EST yk156d6.5 comes from this gene~cDNA EST yk155e6.5 comes from this gene~cDNA EST yk155e6.3 comes from this gene~cD>	gene	gene1689	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2082
SPy_2083	SPy2083		SPy_2083	1734911	1735810	+	putative formiminotransferase cyclodeaminase	Best Blastp hit %3D pir||D72326 hypothetical protein TM0843 - Thermotoga maritima (strain MSB8) >gi|4981376|gb|AAD35925.1|AE001751_5 (AE001751) formiminotransferase- cyclodeaminase/formiminotetrahydrofolate cyclodeaminase%2C putative [Thermotoga maritima]	gene	gene1690	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2083
SPy_2084	SPy2084		SPy_2084	1735821	1736447	+	putative serine cycle enzyme	Best Blastp hit %3D sp|Q49135|SCE4_METEX PUTATIVE SERINE CYCLE ENZYME (ORF4) >gi|1073166|pir||A55230 hypothetical protein (mtkA 5' region) - Methylobacterium extorquens >gi|694120|gb|AAA62653.1| (L33465) methenyl tetrahydrofolate cyclohydrolase [Methylobacterium extorquens]	gene	gene1691	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2084
SPy_2085	SPy2085	fhs.2	fhs.2	1736465	1738138	+	putative formate-tetrahydrofolate ligase	Best Blastp hit %3D sp|P21164|FTHS_MOOTH FORMATE-TETRAHYDROFOLATE LIGASE (FORMYLTETRAHYDROFOLATE SYNTHETASE) (FHS) (FTHFS) >gi|98640|pir||A35942 formate-tetrahydrofolate ligase (EC 6.3.4.3) - Clostridium thermaceticum >gi|144816|gb|AAA23240.1| (J02911) formyltetrahydrofolate synthetase (FTHFS) (ttg start codon) (EC 6.3.4.3) [Moorella thermoacetica]	gene	gene1692	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2085
SPy_2087	SPy2087		SPy_2087	1738160	1738756	+	hypothetical protein	Best Blastp hit %3D gi|10954689 similar to unknown gene next to hutR gene in Pseudomonas putida [Agrobacterium rhizogenes] >gi|8918689|dbj|BAA97754.1| (AB039932) similar to unknown gene next to hutR gene in Pseudomonas putida [Agrobacterium rhizogenes] >gi|10567353|dbj|BAB16162.1| (AP002086) similar to unknown gene next to hutR gene in Pseudomonas putida [Agrobacterium rhizogenes]	gene	gene1693	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2087
SPy_2088	SPy2088		SPy_2088	1738976	1740319	+	putative cationic amino acid transporter protein	Best Blastp hit %3D pir||B69172 cationic amino acid transporter related protein - Methanobacterium thermoautotrophicum (strain Delta H) >gi|2621621|gb|AAB85052.1| (AE000837) cationic amino acid transporter related protein [Methanobacterium thermoautotrophicum]	gene	gene1694	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2088
SPy_2089	SPy2089	hutH	hutH	1740330	1741871	+	putative histidine ammonia-lyase	Best Blastp hit %3D sp|P10944|HUTH_BACSU HISTIDINE AMMONIA-LYASE (HISTIDASE) >gi|68358|pir||UFBSHS histidine ammonia-lyase (EC 4.3.1.3) - Bacillus subtilis >gi|143076|gb|AAA22538.1| (M20659) histidase [Bacillus subtilis] >gi|603770|dbj|BAA06644.1| (D31856) histidase [Bacillus subtilis] >gi|2636481|emb|CAB15971.1| (Z99124) histidase [Bacillus subtilis]	gene	gene1695	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2089
SPy_2090	SPy2090	hutG	hutG	1742057	1743043	+	putative formiminoglutamate hydrolase	Best Blastp hit %3D gb|AAG06563.1|AE004741_8 (AE004741) probable arginase family protein [Pseudomonas aeruginosa]	gene	gene1696	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2090
SPy_2091	SPy2091		SPy_2091	1743074	1746148	-	putative regulatory protein	Best Blastp hit %3D pir||T35822 probable regulatory protein - Streptomyces coelicolor >gi|4467257|emb|CAB37582.1| (AL035569) putative regulatory protein [Streptomyces coelicolor A3(2)]	gene	gene1697	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2091
SPy_2092	SPy2092	rpsB	rpsB	1746452	1747219	+	30S ribosomal protein S2	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P49668|RS2_PEDAC 30S RIBOSOMAL PROTEIN S2 >gi|897795|emb|CAA50276.1| (X70925) 30S ribosomal protein [Pediococcus acidilactici]	gene	gene1698	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2092
SPy_2093	SPy2093	tsf	tsf	1747353	1748393	+	putative elongation factor TS	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D emb|CAB73435.1| (AL139077) elongation factor TS [Campylobacter jejuni]	gene	gene1699	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2093
SPy_2095	SPy2095	pepO	pepO	1748559	1750454	-	putative endopeptidase O	Best Blastp hit %3D gb|AAD40473.1|AF116532_1 (AF116532) endopeptidase O [Streptococcus parasanguinis]	gene	gene1700	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2095
SPy_2096	SPy2096	dexS	dexS	1750662	1752290	-	putative dextran glucosidase	Best Blastp hit %3D gb|AAF71997.1|AF216220_1 (AF216220) alpha-glucosidase [Bacillus sp. DG0303]	gene	gene1701	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2096
SPy_2097	SPy2097		SPy_2097	1752357	1754381	-	putative PTS system enzyme II	Best Blastp hit %3D sp|P36672|PTTB_ECOLI PTS SYSTEM%2C TREHALOSE-SPECIFIC IIBC COMPONENT (EIIBC-TRE) (TREHALOSE-PERMEASE IIBC COMPONENT) (PHOSPHOTRANSFERASE ENZYME II%2C BC COMPONENT) (EII-TRE) >gi|7434464|pir||C65236 phosphotransferase system trehalose permease - Escherichia coli (strain K-12) >gi|2367362|gb|AAC77197.1| (AE000495) PTS system enzyme II%2C trehalose specific [Escherichia coli]	gene	gene1702	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2097
SPy_2099	SPy2099		SPy_2099	1754592	1755305	+	putative transcriptional regulator (GntR family)	Best Blastp hit %3D sp|P39796|TRER_BACSU TREHALOSE OPERON TRANSCRIPTIONAL REPRESSOR >gi|2126928|pir||JC5038 transcription repressor of trehalose operon treR - Bacillus subtilis >gi|2127261|pir||I40499 trehalose repressor treR - Bacillus subtilis >gi|1000453|emb|CAA91016.1| (Z54245) TreR [Bacillus subtilis] >gi|2626829|dbj|BAA23407.1| (D83967) TreR [Bacillus subtilis] >gi|2633106|emb|CAB12611.1| (Z99108) transcriptional regulator (GntR family) [Bacillus subtilis]	gene	gene1703	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2099
SPy_2102	SPy2102		SPy_2102	1755584	1755922	-		This gene contains a point mutation resulting in the creation of an in-frame stop codon	gene	gene1704	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2102
SPy_2103	SPy2103		SPy_2103	1756109	1756966	+	hypothetical protein	Best Blastp hit %3D dbj|BAB07024.1| (AP001518) unknown conserved protein [Bacillus halodurans]	gene	gene1705	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2103
SPy_2104	SPy2104		SPy_2104	1757008	1757739	+	hypothetical protein	Best Blastp hit %3D gb|AAD24446.1|AF118389_3 (AF118389) unknown [Streptococcus suis]	gene	gene1706	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2104
SPy_2105	SPy2105	nrdG	nrdG	1757913	1758527	-	putative anaerobic ribonucleotide reductase activator	Best Blastp hit %3D sp|P45080|NRDG_HAEIN ANAEROBIC RIBONUCLEOSIDE-TRIPHOSPHATE REDUCTASE ACTIVATING PROTEIN (CLASS III ANAEROBIC RIBONUCLEOTIDE REDUCTASE SMALL COMPONENT) >gi|1074665|pir||E64168 anaerobic ribonucleotide reductase activase (EC 1.97.1.-) - Haemophilus influenzae (strain Rd KW20) >gi|1574712|gb|AAC22810.1| (U32795) anaerobic ribonucleoside-triphosphate reductase activating protein (nrdG) [Haemophilus influenzae Rd]	gene	gene1707	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2105
SPy_2106	SPy2106		SPy_2106	1758527	1759036	-	hypothetical protein	Best Blastp hit %3D pir||G75479 hypothetical protein - Deinococcus radiodurans (strain R1) >gi|6458477|gb|AAF10345.1|AE001931_16 (AE001931) hypothetical protein [Deinococcus radiodurans]	gene	gene1708	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2106
SPy_2107	SPy2107		SPy_2107	1759045	1759980	-	putative oxidoreductase	Best Blastp hit %3D emb|CAB95794.1| (AL359949) putative oxidoreductase [Streptomyces coelicolor A3(2)]	gene	gene1709	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2107
SPy_2110	SPy2110	nrdD	nrdD	1760337	1762535	-	putative anaerobic ribonucleoside-triphosphate reductase	Best Blastp hit %3D pir||A47331 ribonucleoside-triphosphate reductase%2C oxygen-sensitive (EC 1.17.4.-) - Escherichia coli >gi|537080|gb|AAA97135.1| (U14003) ribonucleoside triphosphate reductase [Escherichia coli] >gi|1790686|gb|AAC77195.1| (AE000495) anaerobic ribonucleoside-triphosphate reductase [Escherichia coli]	gene	gene1710	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2110
SPy_2111	SPy2111		SPy_2111	1762632	1764191	-	hypothetical protein	Best Blastp hit %3D gb|AAC63652.1| (AC005309) putative putative sister-chromatide cohesion protein [Arabidopsis thaliana]	gene	gene1711	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2111
SPy_2112	SPy2112		SPy_2112	1764604	1764909	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04989.1| (AP001511) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1712	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2112
SPy_2113	SPy2113		SPy_2113	1764921	1765340	-	hypothetical protein	Best Blastp hit %3D dbj|BAB04988.1| (AP001511) unknown conserved protein [Bacillus halodurans]	gene	gene1713	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2113
SPy_2114	SPy2114		SPy_2114	1765337	1765606	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1714	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2114
SPy_2115	SPy2115		SPy_2115	1765719	1766117	-	hypothetical protein	Best Blastp hit %3D sp|O31602|YJBD_BACSU HYPOTHETICAL 15.5 KDA PROTEIN IN OPPF-MECA INTERGENIC REGION >gi|7429507|pir||D69843 conserved hypothetical protein yjbD - Bacillus subtilis >gi|2633504|emb|CAB13007.1| (Z99110) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1715	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2115
SPy_2116	SPy2116	recA	recA	1766408	1767544	-	recombination protein	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D sp|P30758|RECA_STRPN RECA PROTEIN >gi|421436|pir||S30219 recombination protein recA - Streptococcus pneumoniae >gi|47422|emb|CAA78955.1| (Z17307) RecA [Streptococcus pneumoniae] >gi|899420|emb|CAA84072.1| (Z34303) RecA protein [Streptococcus pneumoniae]	gene	gene1716	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2116
SPy_2117	SPy2117	cinA	cinA	1767633	1768904	-	putative competence-damage protein	Best Blastp hit %3D gb|AAC09382.1| (L36131) colligrin [Streptococcus pneumoniae] >gi|1093015|prf||2102309A exp10 gene [Streptococcus pneumoniae]	gene	gene1717	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2117
SPy_2118	SPy2118	tag	tag	1768973	1769533	-	putative 3-methyl-adenine DNA glycosylase I%2C constitutive	Best Blastp hit %3D sp|P05100|3MG1_ECOLI DNA-3-METHYLADENINE GLYCOSYLASE I (3-METHYLADENINE-DNA GLYCOSYLASE I%2C CONSTITUTIVE) (TAG I) (DNA-3-METHYLADENINE GLYCOSIDASE I) >gi|67508|pir||DGECM1 3-methyladenine-DNA glycosylase (EC 3.2.2.-) I - Escherichia coli >gi|43030|emb|CAA27472.1| (X03845) TAGI (aa 1-187) [Escherichia coli] >gi|147920|gb|AAA24658.1| (J02606) 3-methyladenine-DNA glycosylase I (tag) [Escherichia coli] >gi|466687|gb|AAB18526.1| (U00039) 3-methyladenine DNA glycosylase I%2C constitutive [Escherichia coli] >gi|1789971|gb|AAC76573.1| (AE000432) 3-methyl-adenine DNA glycosylase I%2C constitutive [Escherichia coli]	gene	gene1718	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2118
SPy_2119	SPy2119	ruvA	ruvA	1769543	1770139	-	putative Holiday junction DNA helicase	Best Blastp hit %3D sp|O05392|RUVA_BACSU HOLLIDAY JUNCTION DNA HELICASE RUVA >gi|7443689|pir||E69702 Holliday junction DNA helicase ruvA - Bacillus subtilis >gi|2635239|emb|CAB14734.1| (Z99118) Holliday junction DNA helicase [Bacillus subtilis] >gi|6977805|emb|CAB75330.1| (Y15896) RuvA protein [Bacillus subtilis]	gene	gene1719	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2119
SPy_2120	SPy2120	lmrP	lmrP	1770141	1771361	-	putative integral membrane protein	Best Blastp hit %3D gi|10957455 integral membrane protein LmrP [Deinococcus radiodurans] >gi|7473067|pir||H75622 integral membrane protein LmrP - Deinococcus radiodurans (strain R1) >gi|6460884|gb|AAF12588.1|AE001826_57 (AE001826) integral membrane protein LmrP [Deinococcus radiodurans]	gene	gene1720	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2120
SPy_2121	SPy2121	mutL	mutL	1771372	1773354	-	putative DNA mismatch repair protein	Best Blastp hit %3D sp|P49850|MUTL_BACSU DNA MISMATCH REPAIR PROTEIN MUTL >gi|7450493|pir||A69663 DNA mismatch repair mutL - Bacillus subtilis >gi|1002521|gb|AAB19236.1| (U27343) MutL [Bacillus subtilis] >gi|2634077|emb|CAB13578.1| (Z99112) mutL [Bacillus subtilis]	gene	gene1721	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2121
SPy_2122	SPy2122	int4	int4	1773449	1774594	-	putative integrase - phage associated	Best Blastp hit %3D gb|AAA85500.1| (U22342) integrase [Bacteriophage T270]	gene	gene1722	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2122
SPy_2125	SPy2125		SPy_2125	1775853	1776620	-	putative repressor protein - phage associated	Best Blastp hit %3D gi|9635682 repressor [Staphylococcus aureus prophage phiPV83] >gi|8918752|dbj|BAA97812.1| (AB044554) repressor [Staphylococcus aureus prophage phiPV83]	gene	gene1723	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2125
SPy_2126	SPy2126		SPy_2126	1776774	1776980	+	hypothetical protein	Best Blastp hit %3D pir||T13266 hypothetical protein - Lactococcus lactis phage BK5-T >gi|928838|gb|AAA98589.1| (L44593) ORF79%3B putative [Lactococcus lactis phage BK5-T]	gene	gene1724	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2126
SPy_2127	SPy2127		SPy_2127	1777014	1777781	+	hypothetical protein	Best Blastp hit %3D gi|9631452 ORF MSV194 ALI motif gene family protein [Melanoplus sanguinipes entomopoxvirus] >gi|4049805|gb|AAC97765.1| (AF063866) ORF MSV194 ALI motif gene family protein [Melanoplus sanguinipes entomopoxvirus]	gene	gene1725	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2127
SPy_2128	SPy2128		SPy_2128	1777791	1778414	+	hypothetical protein	Best Blastp hit %3D gb|AAF85304.1|AE004058_5 (AE004058) hypothetical protein [Xylella fastidiosa]	gene	gene1726	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2128
SPy_2129	SPy2129		SPy_2129	1778414	1778683	+	hypothetical protein	Best Blastp hit %3D dbj|BAB14159.1| (AK022655) unnamed protein product [Homo sapiens]	gene	gene1727	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2129
SPy_2130	SPy2130		SPy_2130	1778939	1779280	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1728	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2130
SPy_2131	SPy2131		SPy_2131	1779267	1779488	+	hypothetical protein	Best Blastp hit %3D sp|P74120|ENGA_SYNY3 PROBABLE GTP-BINDING PROTEIN ENGA >gi|7450580|pir||S75645 probable GTP binding protein slr1974 - Synechocystis sp. (strain PCC 6803) >gi|1653291|dbj|BAA18206.1| (D90912) hypothetical protein [Synechocystis sp.]	gene	gene1729	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2131
SPy_2132	SPy2132		SPy_2132	1779491	1779682	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1730	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2132
SPy_2133	SPy2133		SPy_2133	1779694	1780023	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1731	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2133
SPy_2134	SPy2134		SPy_2134	1780026	1780298	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1732	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2134
SPy_2135	SPy2135		SPy_2135	1780299	1781156	+	putative replication protein	Best Blastp hit %3D emb|CAB46557.1| (AJ242479) putative replication protein [Streptococcus thermophilus]	gene	gene1733	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2135
SPy_2136	SPy2136		SPy_2136	1781125	1782813	+	putative DNA primase - phage associated	Best Blastp hit %3D emb|CAB46558.1| (AJ242479) putative DNA primase [Streptococcus thermophilus]	gene	gene1734	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2136
SPy_2140	SPy2140		SPy_2140	1783553	1783963	+	hypothetical protein	Best Blastp hit %3D gb|AAA34783.1| (L01992) myosin-like protein [Saccharomyces cerevisiae]	gene	gene1735	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2140
SPy_2142	SPy2142		SPy_2142	1784037	1784525	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1736	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2142
SPy_2144	SPy2144		SPy_2144	1784929	1785291	+	hypothetical protein	Best Blastp hit %3D sp|P26764|RPSF_BACLI RNA POLYMERASE SIGMA-F FACTOR (STAGE II SPORULATION PROTEIN AC) (SPORULATION SIGMA FACTOR) >gi|80104|pir||C37165 transcription initiation factor sigma spoIIAC - Bacillus licheniformis >gi|304173|gb|AAA22797.1| (M25260) sporulation protein [Bacillus licheniformis]	gene	gene1737	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2144
SPy_2145	SPy2145		SPy_2145	1785266	1785649	+	hypothetical protein	Best Blastp hit %3D gi|9635007 gp137 [Streptococcus thermophilus bacteriophage Sfi11] >gi|7523568|gb|AAF63071.1|AF158600_26 (AF158600) gp137 [Streptococcus thermophilus bacteriophage Sfi11]	gene	gene1738	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2145
SPy_2147	SPy2147		SPy_2147	1785823	1786398	+	hypothetical protein	Best Blastp hit %3D gb|AAC44560.1| (U41852) hsf [Haemophilus influenzae]	gene	gene1739	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2147
SPy_2148	SPy2148	mutS	mutS	1787012	1789567	-	putative DNA mismatch repair protein	Best Blastp hit %3D sp|P49849|MUTS_BACSU DNA MISMATCH REPAIR PROTEIN MUTS >gi|7448109|pir||C69663 DNA mismatch repair (recognition) mutS - Bacillus subtilis >gi|2634076|emb|CAB13577.1| (Z99112) mutS [Bacillus subtilis]	gene	gene1740	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2148
SPy_2149	SPy2149		SPy_2149	1789554	1789760	-	hypothetical protein	Best Blastp hit %3D gi|9507280 pGP1-D [Plasmid pCHL1] >gi|320442|pir||A37386 dnaB protein homolog - Chlamydia trachomatis (serotype D) plasmid pCHL1 >gi|144465|gb|AAA91569.1| (J03321) pGP1-D [Plasmid pCHL1] >gi|448541|prf||1917253C pGP1-D gene [Chlamydia trachomatis]	gene	gene1741	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2149
SPy_2150	SPy2150	ahrC	ahrC	1789903	1790340	-	putative arginine repressor	Best Blastp hit %3D gb|AAF86983.1|AF282249_2 (AF282249) AhrC [Lactococcus lactis subsp. lactis]	gene	gene1742	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2150
SPy_2151	SPy2151	argS	argS	1790631	1792322	+	putative arginyl-tRNA synthetase	Best Blastp hit %3D gb|AAF86984.1|AF282249_3 (AF282249) ArgS [Lactococcus lactis subsp. lactis]	gene	gene1743	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2151
SPy_2152	SPy2152		SPy_2152	1792410	1792718	+	hypothetical protein	Best Blastp hit %3D dbj|BAA11330.1| (D78257) BacB [Enterococcus faecalis]	gene	gene1744	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2152
SPy_2153	SPy2153		SPy_2153	1792745	1793617	-	hypothetical protein	Best Blastp hit %3D sp|P42978|YPJC_BACSU HYPOTHETICAL 23.6 KD PROTEIN IN QCRC-DAPB INTERGENIC REGION >gi|7450569|pir||C69937 conserved hypothetical protein ypjC - Bacillus subtilis >gi|755601|gb|AAA92872.1| (L38424) unknown [Bacillus subtilis] >gi|1146232|gb|AAB38440.1| (L47709) putative [Bacillus subtilis] >gi|2634669|emb|CAB14167.1| (Z99115) alternate gene name: jojC~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1745	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2153
SPy_2154	SPy2154		SPy_2154	1793660	1794538	-	hypothetical protein	Best Blastp hit %3D sp|P42978|YPJC_BACSU HYPOTHETICAL 23.6 KD PROTEIN IN QCRC-DAPB INTERGENIC REGION >gi|7450569|pir||C69937 conserved hypothetical protein ypjC - Bacillus subtilis >gi|755601|gb|AAA92872.1| (L38424) unknown [Bacillus subtilis] >gi|1146232|gb|AAB38440.1| (L47709) putative [Bacillus subtilis] >gi|2634669|emb|CAB14167.1| (Z99115) alternate gene name: jojC~similar to hypothetical proteins [Bacillus subtilis]	gene	gene1746	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2154
SPy_2155	SPy2155		SPy_2155	1794558	1795499	-	hypothetical protein	Best Blastp hit %3D sp|P39803|YITT_BACSU HYPOTHETICAL 30.5 KD PROTEIN IN IPI 5'REGION (ORF1) >gi|625883|pir||A49921 conserved hypothetical protein yitT - Bacillus subtilis >gi|451201|dbj|BAA03818.1| (D16311) ORF1 [Bacillus subtilis]	gene	gene1747	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2155
SPy_2156	SPy2156	aspS	aspS	1795492	1797240	-	putative aspartyl-tRNA synthetase	Best Blastp hit %3D sp|O32038|SYD_BACSU ASPARTYL-TRNA SYNTHETASE (ASPARTATE-TRNA LIGASE) (ASPRS) >gi|7437581|pir||D69591 aspartate-tRNA ligase (EC 6.1.1.12) aspS - Bacillus subtilis >gi|2635219|emb|CAB14714.1| (Z99118) aspartyl-tRNA synthetase [Bacillus subtilis]	gene	gene1748	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2156
SPy_2157	SPy2157	hisS	hisS	1797578	1798858	-	putative histidine-tRNA ligase	Best Blastp hit %3D pir||S30232 histidine-tRNA ligase (EC 6.1.1.21) - Streptococcus equisimilis (fragment) >gi|1333826|emb|CAA78919.1| (Z17214) histidine-tRNA ligase [Streptococcus equisimilis]	gene	gene1749	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2157
SPy_2159	SPy2159	rpmF	rpmF	1799078	1799260	+	50S ribosomal protein L32	Best Blastp hit %3D sp|O34101|RL32_LACLC 50S RIBOSOMAL PROTEIN L32 >gi|2327029|gb|AAB66691.1| (U89998) 50S ribosomal protein subunit L32 [Lactococcus lactis subsp. cremoris]	gene	gene1750	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2159
SPy_2160	SPy2160	rpmG	rpmG	1799276	1799425	+	50S ribosomal protein L33	Best Blastp hit %3D sp|O34102|RL33_LACLC 50S RIBOSOMAL PROTEIN L33 >gi|2327030|gb|AAB66692.1| (U89998) 50S ribosomal protein subunit L33 [Lactococcus lactis subsp. cremoris]	gene	gene1751	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2160
SPy_2162	SPy2162	cadD	cadD	1799718	1800332	+	putative cadmium resistance protein	Best Blastp hit %3D pir||D81021 cadmium resistance protein NMB1955 [imported] - Neisseria meningitidis (group B strain MD58) >gi|7227215|gb|AAF42284.1| (AE002544) cadmium resistance protein [Neisseria meningitidis MC58]	gene	gene1752	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2162
SPy_2163	SPy2163	cadC	cadC	1800344	1800682	+	putative cadmium efflux system accessory	Best Blastp hit %3D gi|10956778 CadX [Staphylococcus lugdunensis] >gi|1658281|gb|AAB18271.1| (U74623) CadX [Staphylococcus lugdunensis]	gene	gene1753	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2163
SPy_2164	SPy2164		SPy_2164	1800712	1801656	+	hypothetical protein	Best Blastp hit %3D gi|9964470 AMV156 [Amsacta moorei entomopoxvirus] >gi|9944679|gb|AAG02862.1|AF250284_156 (AF250284) AMV156 [Amsacta moorei entomopoxvirus]	gene	gene1754	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2164
SPy_2165	SPy2165		SPy_2165	1801722	1802474	+	hypothetical protein	Best Blastp hit %3D gb|AAB60012.1| (U09422) ORF21 [Enterococcus faecalis] >gi|1097934|prf||2114402D ORF 21 [Enterococcus faecalis]	gene	gene1755	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2165
SPy_2166	SPy2166		SPy_2166	1802471	1803073	+	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1756	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2166
SPy_2169	SPy2169		SPy_2169	1804284	1805126	+	hypothetical protein	Best Blastp hit %3D dbj|BAB05788.1| (AP001514) unknown conserved protein in others [Bacillus halodurans]	gene	gene1757	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2169
SPy_2170	SPy2170		SPy_2170	1805173	1805814	-	hypothetical protein	Best Blastp hit %3D no blast hits	gene	gene1758	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2170
SPy_2172	SPy2172		SPy_2172	1806021	1806347	+	hypothetical protein	Best Blastp hit %3D sp|P39044|R14H_BACSH 30S RIBOSOMAL PROTEIN S14 HOMOLOG >gi|322159|pir||S31619 gene X protein - Bacillus sphaericus >gi|40067|emb|CAA49519.1| (X69895) X [Bacillus sphaericus]	gene	gene1759	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2172
SPy_2173	SPy2173		SPy_2173	1806334	1806921	+	hypothetical protein	Best Blastp hit %3D sp|P45711|YNEK_BACSU HYPOTHETICAL 17.0 KD PROTEIN IN CCDC-CITB INTERGENIC REGION >gi|7475981|pir||D69891 yneK protein - Bacillus subtilis >gi|1405452|emb|CAA97597.1| (Z73234) YneK [Bacillus subtilis] >gi|2634180|emb|CAB13680.1| (Z99113) alternate gene name: yoxJ [Bacillus subtilis]	gene	gene1760	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2173
SPy_2174	SPy2174		SPy_2174	1806918	1807997	+	hypothetical protein	Best Blastp hit %3D gb|AAF04457.1|AF078161_1 (AF078161) lacunin [Manduca sexta]	gene	gene1761	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2174
SPy_2176	SPy2176		SPy_2176	1808115	1810388	-	hypothetical protein	Best Blastp hit %3D gb|AAC14610.1| (U95842) transmembrane protein Tmp7 [Lactococcus lactis]	gene	gene1762	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2176
SPy_2177	SPy2177		SPy_2177	1810523	1811056	+	putative transcriptional regulator (TetR/AcrR family)	Best Blastp hit %3D dbj|BAB04438.1| (AP001509) transcriptional regulator (TetR/AcrR family) [Bacillus halodurans]	gene	gene1763	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2177
SPy_2178	SPy2178	rpsD	rpsD	1811210	1811821	-	30S ribosomal protein S4	Best Blastp hit %3D dbj|BAB06928.1| (AP001518) ribosomal protein S4 (BS4) [Bacillus halodurans]	gene	gene1764	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2178
SPy_2180	SPy2180		SPy_2180	1812112	1813245	-	putative transposase	Best Blastp hit %3D gb|AAD00760.1| (U93592) putative transposase [Vibrio anguillarum]	gene	gene1765	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2180
SPy_2181	SPy2181		SPy_2181	1813877	1814149	-	hypothetical protein	Best Blastp hit %3D dbj|BAB03778.1| (AP001507) unknown conserved protein in B. subtilis [Bacillus halodurans]	gene	gene1766	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2181
SPy_2182	SPy2182	holB	holB	1814166	1815533	-	DNA polymerase III delta prime subunit	Best Blastp hit %3D sp|P37469|DNAC_BACSU REPLICATIVE DNA HELICASE >gi|2127189|pir||S65970 replicative DNA helicase dnaC - Bacillus subtilis >gi|467330|dbj|BAA05176.1| (D26185) replicative DNA helicase [Bacillus subtilis] >gi|2636591|emb|CAB16081.1| (Z99124) replicative DNA helicase [Bacillus subtilis]	gene	gene1767	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2182
SPy_2183	SPy2183	rplI	rplI	1815563	1816015	-	50S ribosomal protein L9	Best Blastp hit %3D sp|P02417|RL9_BACST 50S RIBOSOMAL PROTEIN L9 (BL17) >gi|279653|pir||R5BS7F ribosomal protein L9 - Bacillus stearothermophilus >gi|7767187|pdb|487D|K Chain K%2C Seven Ribosomal Proteins Fitted To A Cryo-Electron Microscopic Map Of The Large 50s Subunit At 7.5 Angstroms Resolution >gi|1942714|pdb|1DIV| Ribosomal Protein L9	gene	gene1768	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2183
SPy_2184	SPy2184		SPy_2184	1816012	1817988	-	hypothetical protein	Best Blastp hit %3D sp|P37484|YYBT_BACSU HYPOTHETICAL 74.3 KD PROTEIN IN RPLI-COTF INTERGENIC REGION >gi|2126987|pir||S65976 yybT protein - Bacillus subtilis >gi|467336|dbj|BAA05182.1| (D26185) unknown [Bacillus subtilis] >gi|2636598|emb|CAB16088.1| (Z99124) yybT [Bacillus subtilis]	gene	gene1769	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2184
SPy_2185	SPy2185	gidA	gidA	1818079	1819977	-	glucose inhibited division protein	Best Blastp hit %3D sp|O32806|GIDA_LACLC GLUCOSE INHIBITED DIVISION PROTEIN A >gi|2281305|gb|AAC45494.1| (U80409) glucose inhibited division protein homolog GidA [Lactococcus lactis subsp. cremoris]	gene	gene1770	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2185
SPy_2186	SPy2186		SPy_2186	1820101	1820418	-	hypothetical protein	Best Blastp hit %3D gb|AAB53126.1| (L39923) L222-ORF6%3B putative [Mycobacterium leprae]	gene	gene1771	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2186
SPy_2188	SPy2188		SPy_2188	1821195	1822316	-	putative tRNA-(5-methylaminomethyl-2-thiouridylate)	Best Blastp hit %3D sp|O35020|TRMU_BACSU PROBABLE TRNA (5-METHYLAMINOMETHYL-2-THIOURIDYLATE)-METHYLTRANSFERASE	gene	gene1772	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2188
SPy_2189	SPy2189	sdhB	sdhB	1822614	1823285	+	putative L-serine dehydratase beta subunit	Best Blastp hit %3D dbj|BAB06216.1| (AP001515) L-serine dehydratase beta subunit [Bacillus halodurans]	gene	gene1773	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2189
SPy_2190	SPy2190	sdhA	sdhA	1823297	1824169	+	putative L-serine dehydratase alpha subunit	Best Blastp hit %3D dbj|BAB06215.1| (AP001515) L-serine dehydratase alpha subunit [Bacillus halodurans]	gene	gene1774	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2190
SPy_2191	SPy2191		SPy_2191	1824582	1825196	-	hypothetical protein	Best Blastp hit %3D gb|AAF66691.1|AF144681_1 (AF144681) immunodominant antigen A [Staphylococcus aureus]	gene	gene1775	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2191
SPy_2193	SPy2193		SPy_2193	1825568	1826368	-	hypothetical protein	Best Blastp hit %3D pir||T44414 hypothetical protein ybaF [imported] - Bacillus halodurans >gi|4512435|dbj|BAA75302.1| (AB017508) ybaF homologue (identity of 59%25 to B. subtilis) [Bacillus halodurans] >gi|10172778|dbj|BAB03885.1| (AP001507) unknown conserved protein [Bacillus halodurans]	gene	gene1776	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2193
SPy_2194	SPy2194		SPy_2194	1826361	1827203	-	putative ABC transporter (ATP-binding protein)	Best Blastp hit %3D dbj|BAB03884.1| (AP001507) ABC transporter (ATP-binding protein) [Bacillus halodurans]	gene	gene1777	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2194
SPy_2195	SPy2195		SPy_2195	1827179	1828069	-	ABC transporter (ATP-binding protein)	Best Blastp hit %3D sp|P40735|YBXA_BACSU HYPOTHETICAL ABC TRANSPORTER ATP-BINDING PROTEIN YBXA >gi|7445713|pir||E69751 ABC transporter (ATP-binding protein) homolog ybxA - Bacillus subtilis >gi|1644202|dbj|BAA10983.1| (D64126) unknown [Bacillus subtilis] >gi|2632412|emb|CAB11921.1| (Z99104) alternate gene name: ybaD~similar to ABC transporter (ATP-binding protein) [Bacillus subtilis]	gene	gene1778	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2195
SPy_2196	SPy2196	pgsA	pgsA	1828020	1828562	-	phosphatidylglycerophosphate synthase	Best Blastp hit %3D pir||I39950 pgsA protein - Bacillus subtilis >gi|893358|dbj|BAA46041.1| (D50064) PgsA [Bacillus subtilis] >gi|1842439|gb|AAB47707.1| (U87792) phosphatidylglycerophosphate synthase [Bacillus subtilis]	gene	gene1779	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2196
SPy_2197	SPy2197		SPy_2197	1828576	1829601	-	hypothetical protein	Best Blastp hit %3D gb|AAB47706.1| (U87792) unknown [Bacillus subtilis]	gene	gene1780	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2197
SPy_2198	SPy2198		SPy_2198	1829651	1830940	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06111.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1781	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2198
SPy_2199	SPy2199		SPy_2199	1830942	1832186	-	hypothetical protein	Best Blastp hit %3D dbj|BAB06112.1| (AP001515) unknown conserved protein [Bacillus halodurans]	gene	gene1782	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2199
SPy_2200	SPy2200	hasA	hasA	1832617	1833876	+	hyaluronate synthase	Best Blastp hit %3D pir||A53100 hyaluronate synthase A (HasA) - Streptococcus sp. (group A) >gi|473747|gb|AAA17725.1| (L21187) hyaluronate synthase [Streptococcus pyogenes]	gene	gene1783	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2200
SPy_2201	SPy2201	hasB	hasB	1833912	1835120	+	UDP-glucose 6-dehydrogenase	Best Blastp hit %3D sp|Q07172|UDG_STRPY UDP-GLUCOSE 6-DEHYDROGENASE (UDP-GLC DEHYDROGENASE) (UDP-GLCDH) (UDPGDH) >gi|1075776|pir||A46089 UDPglucose 6-dehydrogenase (EC 1.1.1.22) - Streptococcus pyogenes >gi|8569328|pdb|1DLI|A Chain A%2C The First Structure Of Udp-Glucose Dehydrogenase (Udpgdh) Reveals The Catalytic Residues Necessary For The Two-Fold Oxidation >gi|295189|gb|AAA26899.1| (L08444) UDP-glucose hydrogenase [Streptococcus pyogenes]	gene	gene1784	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2201
SPy_2202	SPy2202	hasC	hasC	1835302	1836216	+	UDP-glucose pyrophosphorylase	Best Blastp hit %3D sp|Q54713|HASC_STRPY UTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) >gi|995767|gb|AAA91810.1| (U33452) UDP-glucose pyrophosphorylase [Streptococcus pyogenes]	gene	gene1785	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2202
SPy_2203	SPy2203		SPy_2203	1836524	1836937	+	hypothetical protein	Best Blastp hit %3D pir||JC4754 hypothetical 13.6k protein - Lactococcus lactis >gi|1107709|emb|CAA61548.1| (X89367) orf121 [Lactococcus lactis]	gene	gene1786	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2203
SPy_2204	SPy2204	recF	recF	1836939	1838045	+	RecF protein	Best Blastp hit %3D sp|P49999|RECF_STRPY RECF PROTEIN >gi|1075773|pir||JC4077 recF protein - Streptococcus pyogenes >gi|533080|gb|AAA85783.1| (U07342) RecF protein [Streptococcus pyogenes]	gene	gene1787	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2204
SPy_2205	SPy2205		SPy_2205	1838100	1838933	-	hypothetical protein	Best Blastp hit %3D sp|P40419|YCXE_BACME HYPOTHETICAL 30.5 KD PROTEIN IN GDHI 5'REGION (ORF 2) >gi|80122|pir||JS0384 hypothetical 30.5K chain - Bacillus megaterium >gi|216267|dbj|BAA14098.1| (D90043) ORF2 [Bacillus megaterium] >gi|228656|prf||1808263B gdhI upstream ORF2 [Bacillus megaterium]	gene	gene1788	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2205
SPy_2206	SPy2206	guaB	guaB	1839165	1840646	-	inosine monophosphate dehydrogenase	The N-terminal amino acid sequence of this ORF has been determined from a spot isolated by 2-D gel electrophoresis from another strain of S. pyogenes. Hogan%2C D. A.%2C Whitton%2C M. M.%2C Rogers%2C J. and R. A. VanBogelen. 2000. Two-dimensional gel electrophoresis map of Streptococcus pyogenes proteins. Unpublished data.%3B Best Blastp hit %3D pdb|1ZFJ|A Chain A%2C Inosine Monophosphate Dehydrogenase (Impdh%3B Ec 1.1.1.205) From Streptococcus Pyogenes	gene	gene1789	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2206
SPy_2207	SPy2207	trsA	trsA	1840954	1841976	-	putative tryptophanyl-tRNA synthetase	Best Blastp hit %3D pir||E75438 tryptophanyl-tRNA synthetase - Deinococcus radiodurans (strain R1) >gi|6458825|gb|AAF10665.1|AE001959_5 (AE001959) tryptophanyl-tRNA synthetase [Deinococcus radiodurans]	gene	gene1790	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2207
SPy_2209	SPy2209		SPy_2209	1842395	1843267	+	hypothetical protein	Best Blastp hit %3D pir||D70042 conserved hypothetical protein yvjA - Bacillus subtilis >gi|2618831|gb|AAC67260.1| (AF017113) YvjA [Bacillus subtilis] >gi|2636054|emb|CAB15545.1| (Z99122) similar to hypothetical proteins [Bacillus subtilis]	gene	gene1791	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2209
SPy_2210	SPy2210		SPy_2210	1843346	1844965	+	ABC transporter%2C ATP-binding protein	Best Blastp hit %3D pir||E69861 ABC transporter (ATP-binding protein) homolog ykpA - Bacillus subtilis >gi|2633814|emb|CAB13316.1| (Z99111) similar to ABC transporter (ATP-binding protein) [Bacillus subtilis] >gi|3282128|gb|AAC24918.1| (AF012285) YkpA [Bacillus subtilis]	gene	gene1792	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2210
SPy_2211	SPy2211		SPy_2211	1845048	1847624	+	hypothetical protein	Best Blastp hit %3D gb|AAC14608.1| (U95840) transmembrane protein Tmp5 [Lactococcus lactis]	gene	gene1793	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2211
SPy_2214	SPy2214		SPy_2214	1848499	1849264	-		transposase%3B This gene contains multiple sequence confirmed frame shift mutations	gene	gene1796	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2214
SPy_2215	SPy2215		SPy_2215	1849653	1850132	-	hypothetical protein	Best Blastp hit %3D gb|AAC44439.1| (U33315) orfL [Streptococcus pneumoniae]	gene	gene1798	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2215
SPy_2216	SPy2216	htrA	htrA	1850344	1851567	+	putative serine protease	Best Blastp hit %3D gb|AAC45334.1| (AF000658) putative serine protease [Streptococcus pneumoniae]	gene	gene1799	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2216
SPy_2217	SPy2217	spoJ	spoJ	1851626	1852432	+	putative chromosome segregation protein	Best Blastp hit %3D gb|AAF71537.1|AF255728_3 (AF255728) SpoJ [Streptococcus pyogenes]	gene	gene1800	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_2217
SPy_r01	SPy_r01		SPy_r01	17169	18503	+	16S ribosomal RNA		rRNA	gene12	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r01
SPy_r02	SPy_r02		SPy_r02	19036	21936	+	23S ribosomal RNA		rRNA	gene14	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r02
SPy_r03	SPy_r03		SPy_r03	23170	24504	+	16S ribosomal RNA		rRNA	gene24	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r03
SPy_r04	SPy_r04		SPy_r04	25037	27937	+	23S ribosomal RNA		rRNA	gene26	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r04
SPy_r05	SPy_r05		SPy_r05	79388	80722	+	16S ribosomal RNA		rRNA	gene88	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r05
SPy_r06	SPy_r06		SPy_r06	81255	84157	+	23S ribosomal RNA		rRNA	gene90	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r06
SPy_r07	SPy_r07		SPy_r07	264453	265788	+	16S ribosomal RNA		rRNA	gene264	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r07
SPy_r08	SPy_r08		SPy_r08	266321	269224	+	23S ribosomal RNA		rRNA	gene266	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r08
SPy_r09	SPy_r09		SPy_r09	1331310	1334212	-	23S ribosomal RNA		rRNA	gene1323	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r09
SPy_r10	SPy_r10		SPy_r10	1334745	1336079	-	16S ribosomal RNA		rRNA	gene1325	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r10
SPy_r11	SPy_r11		SPy_r11	1578237	1581146	-	23S ribosomal RNA		rRNA	gene1556	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r11
SPy_r12	SPy_r12		SPy_r12	1581679	1583013	-	16S ribosomal RNA		rRNA	gene1558	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_r12
SPy_s01	SPy_s01		SPy_s01	1065025	1065369	+		The tmRNA gene is the integration site for bacteriophage T12	tmRNA	gene1061	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_s01
SPy_t01	SPy_t01		SPy_t01	18665	18740	+	tRNA-Ala		tRNA	gene13	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t01
SPy_t02	SPy_t02		SPy_t02	22157	22229	+	tRNA-Val		tRNA	gene15	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t02
SPy_t03	SPy_t03		SPy_t03	22247	22319	+	tRNA-Asp		tRNA	gene16	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t03
SPy_t04	SPy_t04		SPy_t04	22351	22423	+	tRNA-Lys		tRNA	gene17	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t04
SPy_t05	SPy_t05		SPy_t05	22429	22510	+	tRNA-Leu		tRNA	gene18	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t05
SPy_t06	SPy_t06		SPy_t06	22521	22593	+	tRNA-Thr		tRNA	gene19	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t06
SPy_t07	SPy_t07		SPy_t07	22606	22677	+	tRNA-Gly		tRNA	gene20	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t07
SPy_t08	SPy_t08		SPy_t08	22686	22770	+	tRNA-Leu		tRNA	gene21	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t08
SPy_t09	SPy_t09		SPy_t09	22787	22863	+	tRNA-Arg		tRNA	gene22	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t09
SPy_t10	SPy_t10		SPy_t10	22867	22940	+	tRNA-Pro		tRNA	gene23	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t10
SPy_t11	SPy_t11		SPy_t11	24666	24741	+	tRNA-Ala		tRNA	gene25	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t11
SPy_t12	SPy_t12		SPy_t12	28158	28230	+	tRNA-Val		tRNA	gene27	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t12
SPy_t13	SPy_t13		SPy_t13	28236	28306	+	tRNA-Gly		tRNA	gene28	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t13
SPy_t14	SPy_t14		SPy_t14	28341	28414	+	tRNA-Ile		tRNA	gene29	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t14
SPy_t15	SPy_t15		SPy_t15	28437	28508	+	tRNA-Glu		tRNA	gene30	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t15
SPy_t16	SPy_t16		SPy_t16	28518	28606	+	tRNA-Ser		tRNA	gene31	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t16
SPy_t17	SPy_t17		SPy_t17	28617	28690	+	tRNA-Met		tRNA	gene32	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t17
SPy_t18	SPy_t18		SPy_t18	28711	28783	+	tRNA-Phe		tRNA	gene33	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t18
SPy_t19	SPy_t19		SPy_t19	28796	28866	+	tRNA-Gly		tRNA	gene34	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t19
SPy_t20	SPy_t20		SPy_t20	28901	28974	+	tRNA-Ile		tRNA	gene35	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t20
SPy_t21	SPy_t21		SPy_t21	28984	29071	+	tRNA-Ser		tRNA	gene36	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t21
SPy_t22	SPy_t22		SPy_t22	80884	80959	+	tRNA-Ala		tRNA	gene89	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t22
SPy_t23	SPy_t23		SPy_t23	84377	84449	+	tRNA-Val		tRNA	gene91	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t23
SPy_t24	SPy_t24		SPy_t24	84455	84525	+	tRNA-Gly		tRNA	gene92	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t24
SPy_t25	SPy_t25		SPy_t25	84560	84633	+	tRNA-Ile		tRNA	gene93	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t25
SPy_t26	SPy_t26		SPy_t26	84656	84727	+	tRNA-Glu		tRNA	gene94	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t26
SPy_t27	SPy_t27		SPy_t27	84738	84827	+	tRNA-Ser		tRNA	gene95	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t27
SPy_t28	SPy_t28		SPy_t28	84837	84910	+	tRNA-Met		tRNA	gene96	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t28
SPy_t29	SPy_t29		SPy_t29	84931	85003	+	tRNA-Phe		tRNA	gene97	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t29
SPy_t30	SPy_t30		SPy_t30	85023	85103	+	tRNA-Tyr		tRNA	gene98	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t30
SPy_t31	SPy_t31		SPy_t31	85110	85180	+	tRNA-Trp		tRNA	gene99	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t31
SPy_t32	SPy_t32		SPy_t32	85192	85264	+	tRNA-His		tRNA	gene100	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t32
SPy_t33	SPy_t33		SPy_t33	85274	85344	+	tRNA-Gln		tRNA	gene101	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t33
SPy_t34	SPy_t34		SPy_t34	85364	85447	+	tRNA-Leu		tRNA	gene102	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t34
SPy_t35	SPy_t35		SPy_t35	265950	266025	+	tRNA-Ala		tRNA	gene265	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t35
SPy_t36	SPy_t36		SPy_t36	269433	269506	+	tRNA-Asn		tRNA	gene267	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t36
SPy_t37	SPy_t37		SPy_t37	269586	269659	+	tRNA-Arg		tRNA	gene268	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t37
SPy_t38	SPy_t38		SPy_t38	580349	580420	+	tRNA-Arg		tRNA	gene585	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t38
SPy_t39	SPy_t39		SPy_t39	758344	758424	+	tRNA-Tyr		tRNA	gene743	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t39
SPy_t40	SPy_t40		SPy_t40	758476	758551	+	tRNA-Gln		tRNA	gene744	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t40
SPy_t41	SPy_t41		SPy_t41	759992	760063	+	tRNA-Arg		tRNA	gene746	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t41
SPy_t42	SPy_t42		SPy_t42	1296700	1296770	+	tRNA-Thr		tRNA	gene1289	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t42
SPy_t43	SPy_t43		SPy_t43	1330450	1330521	-	tRNA-Glu		tRNA	gene1316	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t43
SPy_t44	SPy_t44		SPy_t44	1330544	1330617	-	tRNA-Ile		tRNA	gene1317	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t44
SPy_t45	SPy_t45		SPy_t45	1330653	1330725	-	tRNA-Thr		tRNA	gene1318	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t45
SPy_t46	SPy_t46		SPy_t46	1330736	1330817	-	tRNA-Leu		tRNA	gene1319	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t46
SPy_t47	SPy_t47		SPy_t47	1330823	1330895	-	tRNA-Lys		tRNA	gene1320	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t47
SPy_t48	SPy_t48		SPy_t48	1330927	1330999	-	tRNA-Asp		tRNA	gene1321	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t48
SPy_t49	SPy_t49		SPy_t49	1331017	1331089	-	tRNA-Val		tRNA	gene1322	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t49
SPy_t50	SPy_t50		SPy_t50	1334508	1334583	-	tRNA-Ala		tRNA	gene1324	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t50
SPy_t51	SPy_t51		SPy_t51	1430237	1430323	-	tRNA-Ser		tRNA	gene1412	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t51
SPy_t52	SPy_t52		SPy_t52	1568103	1568188	-	tRNA-Leu		tRNA	gene1543	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t52
SPy_t53	SPy_t53		SPy_t53	1577802	1577875	-	tRNA-Arg		tRNA	gene1554	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t53
SPy_t54	SPy_t54		SPy_t54	1577955	1578028	-	tRNA-Asn		tRNA	gene1555	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t54
SPy_t55	SPy_t55		SPy_t55	1581442	1581517	-	tRNA-Ala		tRNA	gene1557	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t55
SPy_t56	SPy_t56		SPy_t56	1663716	1663788	+	tRNA-Lys		tRNA	gene1629	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t56
SPy_t57	SPy_t57		SPy_t57	1728588	1728658	-	tRNA-Cys		tRNA	gene1685	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t57
SPy_t58	SPy_t58		SPy_t58	1848121	1848194	-	tRNA-Asn		tRNA	gene1794	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t58
SPy_t59	SPy_t59		SPy_t59	1848228	1848299	-	tRNA-Glu		tRNA	gene1795	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t59
SPy_t60	SPy_t60		SPy_t60	1849423	1849496	+	tRNA-Arg		tRNA	gene1797	http://www.ncbi.nlm.nih.gov/gene/?term=SPy_t60