locus-tag	class	description
M3B_RS00010	COG0592	DNA-directed DNA polymerase activity
M3B_RS00020	COG0012	GTP binding
M3B_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M3B_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M3B_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M3B_RS00065	COG0531	amino acid
M3B_RS00175	COG3942	CHAP domain
M3B_RS00195	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M3B_RS00205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M3B_RS00220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M3B_RS00240	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M3B_RS00255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M3B_RS00270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M3B_RS00285	COG1012	belongs to the aldehyde dehydrogenase family
M3B_RS00285	COG1454	alcohol dehydrogenase
M3B_RS00290	COG1064	alcohol dehydrogenase
M3B_RS00295	COG0534	Mate efflux family protein
M3B_RS00405	COG0201	protein transport
M3B_RS00550	COG1121	(ABC) transporter
M3B_RS00555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M3B_RS00570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3B_RS00590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M3B_RS00595	COG1459	type II secretion system
M3B_RS00600	COG4537	Required for transformation and DNA binding
M3B_RS00640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M3B_RS00645	COG1363	Peptidase, m42
M3B_RS00660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3B_RS00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M3B_RS00680	COG1428	Deoxynucleoside kinase
M3B_RS00685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M3B_RS00715	COG4509	Sortase family
M3B_RS00740	COG2031	fatty acid transporter
M3B_RS00755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M3B_RS00770	COG0251	oxidation-reduction process
M3B_RS00785	COG1269	ATP hydrolysis coupled proton transport
M3B_RS00790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M3B_RS00800	COG1527	subunit (C
M3B_RS00805	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
M3B_RS00840	COG1744	ABC transporter substrate-binding protein PnrA-like
M3B_RS00880	COG0626	cystathionine gamma-synthase activity
M3B_RS00910	COG3623	hexulose-6-phosphate isomerase
M3B_RS00935	COG3448	diguanylate cyclase activity
M3B_RS00935	COG4175	Glycine betaine
M3B_RS00945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M3B_RS00945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M3B_RS00980	COG1268	BioY protein
M3B_RS00985	COG1234	tRNA 3'-trailer cleavage
M3B_RS01020	COG0705	Rhomboid family
M3B_RS01020	COG0457	Tetratricopeptide repeat
M3B_RS01040	COG1132	(ABC) transporter
M3B_RS01045	COG1132	(ABC) transporter
M3B_RS01055	COG0756	dUTP diphosphatase activity
M3B_RS01080	COG3290	protein histidine kinase activity
M3B_RS01105	COG1847	R3H domain protein
M3B_RS01130	COG1175	transmembrane transport
M3B_RS01135	COG0395	ABC-type sugar transport system, permease component
M3B_RS01145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M3B_RS01160	COG0084	hydrolase, TatD family'
M3B_RS01185	COG1564	THIamine pyrophosphokinase
M3B_RS01200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M3B_RS01240	COG0765	amino acid transport
M3B_RS01260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M3B_RS01270	COG0719	Fe-S assembly protein
M3B_RS01275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M3B_RS01290	COG1686	Belongs to the peptidase S11 family
M3B_RS01295	COG1686	Belongs to the peptidase S11 family
M3B_RS01300	COG4166	transmembrane transport
M3B_RS01305	COG0601	transmembrane transport
M3B_RS01310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M3B_RS01315	COG0444	Belongs to the ABC transporter superfamily
M3B_RS01370	COG0351	phosphomethylpyrimidine kinase
M3B_RS01375	COG4720	Psort location CytoplasmicMembrane, score
M3B_RS01385	COG0668	transmembrane transport
M3B_RS01440	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M3B_RS01455	COG0789	Transcriptional regulator
M3B_RS01460	COG0174	glutamine synthetase
M3B_RS01475	COG1214	PFAM Peptidase M22, glycoprotease
M3B_RS01480	COG0456	acetyltransferase
M3B_RS01500	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
M3B_RS01505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M3B_RS01515	COG2081	HI0933 family
M3B_RS01530	COG0789	Transcriptional regulator
M3B_RS01555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M3B_RS01560	COG2814	Major facilitator Superfamily
M3B_RS01570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M3B_RS01585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M3B_RS01590	COG1882	Formate acetyltransferase
M3B_RS01605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M3B_RS01610	COG0681	Belongs to the peptidase S26 family
M3B_RS01640	COG3118	belongs to the thioredoxin family
M3B_RS01645	COG3620	sequence-specific DNA binding
M3B_RS01650	COG1194	a g-specific adenine glycosylase
M3B_RS01690	COG0006	proline dipeptidase activity
M3B_RS01695	COG2131	deaminase
M3B_RS01715	COG1609	Transcriptional regulator
M3B_RS01720	COG1621	beta-fructofuranosidase activity
M3B_RS01725	COG1263	PTS System
M3B_RS01725	COG2190	(PTS) system
M3B_RS01725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3B_RS01735	COG1940	carbohydrate kinase activity
M3B_RS01740	COG1482	cell wall glycoprotein biosynthetic process
M3B_RS01760	COG3942	CHAP domain
M3B_RS01760	COG1388	LysM domain
M3B_RS01780	COG1120	ATPase activity
M3B_RS01785	COG4988	ABC transporter
M3B_RS01790	COG1132	(ABC) transporter
M3B_RS01805	COG1129	ABC transporter
M3B_RS01815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M3B_RS01830	COG0252	asparaginase activity
M3B_RS01835	COG0561	phosphatase activity
M3B_RS01845	COG0436	Aminotransferase
M3B_RS01855	COG1335	isochorismatase
M3B_RS01865	COG0574	Belongs to the PEP-utilizing enzyme family
M3B_RS01865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M3B_RS01890	COG2261	transglycosylase associated protein
M3B_RS01895	COG0588	phosphoglycerate mutase activity
M3B_RS01930	COG1024	Enoyl-CoA hydratase
M3B_RS01955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M3B_RS01960	COG1028	Short-chain dehydrogenase reductase Sdr
M3B_RS01965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M3B_RS01980	COG0439	Biotin carboxylase
M3B_RS02005	COG5433	transposase activity
M3B_RS02015	COG3716	PTS system mannose fructose sorbose family IID component
M3B_RS02020	COG3715	PTS system
M3B_RS02030	COG0561	phosphatase activity
M3B_RS02035	COG2252	PERMEase
M3B_RS02040	COG0802	atpase or kinase
M3B_RS02050	COG1316	TRANSCRIPTIONal
M3B_RS02060	COG0537	adenosine 5'-monophosphoramidase activity
M3B_RS02065	COG1131	(ABC) transporter
M3B_RS02070	COG4473	ABC transporter
M3B_RS02095	COG0195	Participates in both transcription termination and antitermination
M3B_RS02100	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M3B_RS02130	COG2217	Heavy metal translocating P-type atpase
M3B_RS02190	COG2860	membrane
M3B_RS02195	COG0561	phosphatase activity
M3B_RS02215	COG1283	sodium-dependent phosphate transmembrane transporter activity
M3B_RS02225	COG0656	L-ascorbic acid biosynthetic process
M3B_RS02230	COG1755	Isoprenylcysteine carboxyl methyltransferase
M3B_RS02275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M3B_RS02280	COG0446	pyridine nucleotide-disulphide oxidoreductase
M3B_RS02305	COG1131	(ABC) transporter
M3B_RS02420	COG1783	phage Terminase large subunit
M3B_RS02535	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3B_RS02535	COG1388	LysM domain
M3B_RS02590	COG0513	Belongs to the DEAD box helicase family
M3B_RS02600	COG1126	abc transporter atp-binding protein
M3B_RS02610	COG0492	ferredoxin-NADP+ reductase activity
M3B_RS02615	COG1113	amino acid transport
M3B_RS02620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M3B_RS02630	COG3579	cysteine-type endopeptidase activity
M3B_RS02635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3B_RS02660	COG0116	Belongs to the methyltransferase superfamily
M3B_RS02675	COG2610	gluconate transmembrane transporter activity
M3B_RS02695	COG0183	Belongs to the thiolase family
M3B_RS02700	COG0583	DNA-binding transcription factor activity
M3B_RS02720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M3B_RS02730	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M3B_RS02730	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M3B_RS02740	COG2815	serine threonine protein kinase
M3B_RS02740	COG0515	serine threonine protein kinase
M3B_RS02750	COG4585	Histidine kinase
M3B_RS02755	COG2197	response regulator
M3B_RS02765	COG1098	S1 RNA binding domain
M3B_RS02775	COG1739	Uncharacterized protein family UPF0029
M3B_RS03145	COG0383	alpha-mannosidase activity
M3B_RS03155	COG1609	Transcriptional regulator
M3B_RS03160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
M3B_RS03165	COG2723	6-phospho-beta-galactosidase activity
M3B_RS03170	COG1940	carbohydrate kinase activity
M3B_RS03175	COG1175	transmembrane transport
M3B_RS03180	COG0395	ABC-type sugar transport system, permease component
M3B_RS03185	COG1653	transport
M3B_RS03195	COG2972	Histidine kinase
M3B_RS03200	COG2207	Transcriptional regulator
M3B_RS03200	COG4753	response regulator
M3B_RS03205	COG3250	beta-galactosidase activity
M3B_RS03215	COG2226	methyltransferase
M3B_RS03235	COG1605	Chorismate mutase
M3B_RS03235	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M3B_RS03285	COG0673	inositol 2-dehydrogenase activity
M3B_RS03295	COG0785	Cytochrome C biogenesis protein
M3B_RS03300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M3B_RS03325	COG1396	sequence-specific DNA binding
M3B_RS03335	COG3561	AntA/AntB antirepressor
M3B_RS03370	COG3935	DnaD domain protein
M3B_RS03475	COG1475	DNA binding
M3B_RS03615	COG1388	LysM domain
M3B_RS03615	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3B_RS03660	COG2972	Histidine kinase
M3B_RS03700	COG1288	antiporter activity
M3B_RS03705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M3B_RS03710	COG0549	Belongs to the carbamate kinase family
M3B_RS03720	COG0742	ribosomal rna small subunit methyltransferase
M3B_RS03730	COG3480	Lon protease (S16) C-terminal proteolytic domain
M3B_RS03735	COG1609	Transcriptional regulator
M3B_RS03740	COG4470	Protein conserved in bacteria
M3B_RS03755	COG0783	Belongs to the Dps family
M3B_RS03765	COG1940	carbohydrate kinase activity
M3B_RS03770	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M3B_RS03775	COG1217	gtp-binding protein TYPA
M3B_RS03785	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M3B_RS03810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M3B_RS03825	COG2302	S4 RNA-binding domain
M3B_RS03830	COG3599	regulation of cell shape
M3B_RS03845	COG0494	nUDIX hydrolase
M3B_RS03850	COG0542	response to heat
M3B_RS03855	COG4703	Protein of unknown function (DUF1797)
M3B_RS03860	COG0765	amino acid transport
M3B_RS03870	COG0415	Belongs to the DNA photolyase family
M3B_RS03875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3B_RS03900	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M3B_RS03905	COG1438	arginine binding
M3B_RS03910	COG0497	DNA recombination
M3B_RS03925	COG2755	lipolytic protein G-D-S-L family
M3B_RS03940	COG0582	viral genome integration into host DNA
M3B_RS03950	COG1396	sequence-specific DNA binding
M3B_RS04000	COG3723	Recombinational DNA repair protein, rece pathway
M3B_RS04175	COG4824	toxin secretion phage lysis holin
M3B_RS04195	COG2217	Heavy metal translocating P-type atpase
M3B_RS04210	COG1827	regulation of RNA biosynthetic process
M3B_RS04220	COG2116	formate transmembrane transporter activity
M3B_RS04225	COG0768	penicillin binding
M3B_RS04240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M3B_RS04260	COG0513	Belongs to the DEAD box helicase family
M3B_RS04275	COG2890	protein-(glutamine-N5) methyltransferase activity
M3B_RS04280	COG0204	Acyl-transferase
M3B_RS04285	COG1555	photosystem II stabilization
M3B_RS04285	COG1596	polysaccharide export
M3B_RS04290	COG0658	competence protein
M3B_RS04290	COG2333	competence protein COMEC
M3B_RS04335	COG1187	pseudouridine synthase activity
M3B_RS04350	COG2223	nitrite transmembrane transporter activity
M3B_RS04355	COG4122	O-methyltransferase activity
M3B_RS04370	COG1476	TRANSCRIPTIONal
M3B_RS04395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3B_RS04400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M3B_RS04405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M3B_RS04425	COG0726	polysaccharide deacetylase
M3B_RS04430	COG0513	Belongs to the DEAD box helicase family
M3B_RS04450	COG1956	GAF domain-containing protein
M3B_RS04455	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M3B_RS04465	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
M3B_RS04465	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
M3B_RS04490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
M3B_RS04495	COG4109	DRTGG domain
M3B_RS04545	COG2814	Major facilitator Superfamily
M3B_RS04555	COG1187	pseudouridine synthase activity
M3B_RS04570	COG0157	Belongs to the NadC ModD family
M3B_RS04600	COG2723	6-phospho-beta-galactosidase activity
M3B_RS04620	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3B_RS04630	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3B_RS04635	COG1126	abc transporter atp-binding protein
M3B_RS04640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3B_RS04660	COG1696	Membrane protein involved in D-alanine export
M3B_RS04670	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M3B_RS04675	COG0657	acetylesterase activity
M3B_RS04695	COG3833	ABC-type maltose transport systems, permease component
M3B_RS04700	COG1175	transmembrane transport
M3B_RS04705	COG2182	Extracellular solute-binding protein
M3B_RS04710	COG1609	Transcriptional regulator
M3B_RS04715	COG1640	4-alpha-glucanotransferase
M3B_RS04720	COG0058	SHG alpha-glucan phosphorylase activity
M3B_RS04900	COG0740	serine-type endopeptidase activity
M3B_RS04985	COG1705	Flagellar rod assembly protein muramidase FlgJ
M3B_RS05020	COG0105	UTP biosynthetic process
M3B_RS05055	COG3715	PTS system
M3B_RS05060	COG3716	PTS system mannose fructose sorbose family IID component
M3B_RS05065	COG2972	Histidine kinase
M3B_RS05070	COG2207	Transcriptional regulator
M3B_RS05070	COG4753	response regulator
M3B_RS05080	COG1012	belongs to the aldehyde dehydrogenase family
M3B_RS05095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M3B_RS05125	COG0285	dihydrofolate synthase activity
M3B_RS05160	COG1176	ABC-type spermidine putrescine transport system, permease component I
M3B_RS05165	COG1177	transmembrane transport
M3B_RS05175	COG4565	transcriptional regulatory protein
M3B_RS05180	COG3290	protein histidine kinase activity
M3B_RS05185	COG3493	citrate carrier protein
M3B_RS05200	COG3700	Belongs to the class B bacterial acid phosphatase family
M3B_RS05205	COG0038	chloride channel
M3B_RS05215	COG0628	permease
M3B_RS05225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M3B_RS05240	COG1104	cysteine desulfurase activity
M3B_RS05255	COG2357	RelA SpoT domain protein
M3B_RS05265	COG0564	pseudouridine synthase activity
M3B_RS05270	COG0280	phosphate acetyltransferase
M3B_RS05290	COG1174	glycine betaine transport
M3B_RS05310	COG2233	PERMEase
M3B_RS05335	COG2890	protein-(glutamine-N5) methyltransferase activity
M3B_RS05370	COG1132	(ABC) transporter
M3B_RS05390	COG3764	Sortase (surface protein transpeptidase)
M3B_RS05395	COG0346	lactoylglutathione lyase activity
M3B_RS05415	COG1272	protein, Hemolysin III
M3B_RS05435	COG0758	DNA mediated transformation
M3B_RS05440	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M3B_RS05460	COG0511	ligase activity, forming carbon-carbon bonds
M3B_RS05465	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
M3B_RS05480	COG2851	Citrate transporter
M3B_RS05490	COG0511	ligase activity, forming carbon-carbon bonds
M3B_RS05495	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
M3B_RS05525	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
M3B_RS05545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M3B_RS05555	COG2188	Transcriptional regulator
M3B_RS05575	COG0488	(ABC) transporter
M3B_RS05585	COG0351	phosphomethylpyrimidine kinase
M3B_RS05585	COG0352	thiamine-phosphate diphosphorylase activity
M3B_RS05590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M3B_RS05595	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M3B_RS05595	COG1328	CTP reductase activity
M3B_RS05600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M3B_RS05630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M3B_RS05650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M3B_RS05655	COG4684	Psort location CytoplasmicMembrane, score
M3B_RS05660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M3B_RS05665	COG1079	Belongs to the binding-protein-dependent transport system permease family
M3B_RS05670	COG4603	Belongs to the binding-protein-dependent transport system permease family
M3B_RS05675	COG3845	ABC transporter
M3B_RS05680	COG1744	ABC transporter substrate-binding protein PnrA-like
M3B_RS05685	COG0295	cytidine deaminase activity
M3B_RS05690	COG2813	Specifically methylates the guanine in position
M3B_RS05705	COG5002	protein histidine kinase activity
M3B_RS05710	COG0745	RESPONSE REGULATOR receiver
M3B_RS05725	COG0704	Plays a role in the regulation of phosphate uptake
M3B_RS05740	COG0581	inorganic phosphate transmembrane transporter activity
M3B_RS05745	COG0573	inorganic phosphate transmembrane transporter activity
M3B_RS05755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M3B_RS05755	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
M3B_RS05760	COG0483	inositol monophosphate 1-phosphatase activity
M3B_RS05775	COG0196	riboflavin kinase activity
M3B_RS05805	COG4591	ABC-type transport system involved in lipoprotein release permease component
M3B_RS05805	COG1136	(ABC) transporter
M3B_RS05855	COG1115	amino acid carrier protein
M3B_RS05860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M3B_RS05870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3B_RS05875	COG1126	abc transporter atp-binding protein
M3B_RS05880	COG0765	amino acid transport
M3B_RS05885	COG2824	Alkylphosphonate utilization operon protein PhnA
M3B_RS05900	COG0469	pyruvate kinase activity
M3B_RS05915	COG1725	Transcriptional regulator
M3B_RS05920	COG1131	(ABC) transporter
M3B_RS05950	COG3177	Filamentation induced by cAMP protein fic
M3B_RS05955	COG1388	LysM domain
M3B_RS05955	COG0860	N-Acetylmuramoyl-L-alanine amidase
M3B_RS06045	COG0740	serine-type endopeptidase activity
M3B_RS06090	COG0582	viral genome integration into host DNA
M3B_RS06150	COG1484	DNA-dependent DNA replication
M3B_RS06160	COG0305	Participates in initiation and elongation during chromosome replication
M3B_RS06225	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
M3B_RS06230	COG1518	maintenance of DNA repeat elements
M3B_RS06245	COG0647	UMP catabolic process
M3B_RS06255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M3B_RS06275	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M3B_RS06280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M3B_RS06285	COG3442	glutamine amidotransferase
M3B_RS06290	COG0095	Lipoate-protein ligase
M3B_RS06295	COG5492	domain, Protein
M3B_RS06315	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3B_RS06320	COG0022	dehydrogenase e1 component
M3B_RS06320	COG0508	dehydrogenase complex catalyzes the overall conversion of
M3B_RS06325	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M3B_RS06330	COG0488	(ABC) transporter
M3B_RS06350	COG1129	ABC transporter
M3B_RS06370	COG1293	RNA-binding protein homologous to eukaryotic snRNP
M3B_RS06375	COG0457	Tetratricopeptide repeat
M3B_RS06380	COG0628	permease
M3B_RS06385	COG1051	belongs to the nudix hydrolase family
M3B_RS06390	COG1088	dTDP-glucose 4,6-dehydratase activity
M3B_RS06400	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M3B_RS06405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M3B_RS06415	COG2384	SAM-dependent methyltransferase
M3B_RS06420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M3B_RS06435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M3B_RS06435	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M3B_RS06440	COG0300	oxidoreductase activity
M3B_RS06450	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M3B_RS06455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M3B_RS06500	COG0539	negative regulation of cytoplasmic translation
M3B_RS06520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M3B_RS06530	COG0187	DNA topoisomerase II activity
M3B_RS06550	COG0765	amino acid transport
M3B_RS06555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3B_RS06580	COG0583	DNA-binding transcription factor activity
M3B_RS06640	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M3B_RS06650	COG3425	synthase
M3B_RS06685	COG0745	RESPONSE REGULATOR receiver
M3B_RS06690	COG2357	RelA SpoT domain protein
M3B_RS06695	COG0737	Belongs to the 5'-nucleotidase family
M3B_RS06700	COG0242	peptide deformylase activity
M3B_RS06715	COG0488	(ABC) transporter
M3B_RS06735	COG0105	UTP biosynthetic process
M3B_RS06760	COG1388	LysM domain
M3B_RS06760	COG1705	Flagellar rod assembly protein muramidase FlgJ
M3B_RS06765	COG1388	LysM domain
M3B_RS06765	COG1705	Flagellar rod assembly protein muramidase FlgJ
M3B_RS06770	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3B_RS06770	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M3B_RS06770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M3B_RS06775	COG1105	Belongs to the carbohydrate kinase PfkB family
M3B_RS06780	COG1349	DNA-binding transcription factor activity
M3B_RS06830	COG1837	Belongs to the UPF0109 family
M3B_RS06840	COG0584	glycerophosphoryl diester phosphodiesterase
M3B_RS06845	COG0577	efflux transmembrane transporter activity
M3B_RS06850	COG1136	(ABC) transporter
M3B_RS06855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M3B_RS06890	COG0564	pseudouridine synthase activity
M3B_RS06900	COG0583	DNA-binding transcription factor activity
M3B_RS06910	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M3B_RS06935	COG1104	cysteine desulfurase activity
M3B_RS06945	COG0285	dihydrofolate synthase activity
M3B_RS06950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M3B_RS06970	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M3B_RS06975	COG1368	sulfuric ester hydrolase activity
M3B_RS07035	COG1216	Glycosyl transferase, family 2
M3B_RS07080	COG2151	metal-sulfur cluster biosynthetic enzyme
M3B_RS07085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M3B_RS07090	COG0358	DNA primase activity
M3B_RS07095	COG1970	mechanosensitive ion channel activity
M3B_RS07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3B_RS07130	COG0577	efflux transmembrane transporter activity
M3B_RS07215	COG1597	lipid kinase activity
M3B_RS07225	COG4708	membrane
M3B_RS07250	COG1131	(ABC) transporter
M3B_RS07325	COG0038	chloride channel
M3B_RS07335	COG0716	FMN binding
M3B_RS07340	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M3B_RS07350	COG2222	sugar isomerase
M3B_RS07355	COG2188	Transcriptional regulator
M3B_RS07390	COG0436	Aminotransferase
M3B_RS07395	COG1199	ATP-dependent helicase activity
M3B_RS07395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M3B_RS07410	COG2177	Part of the ABC transporter FtsEX involved in
M3B_RS07415	COG2884	Cell division ATP-binding protein ftsE
M3B_RS07425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M3B_RS07430	COG0546	phosphoglycolate phosphatase activity
M3B_RS07435	COG0800	Aldolase
M3B_RS07450	COG1028	Short-chain dehydrogenase reductase Sdr
M3B_RS07465	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3B_RS07470	COG3715	PTS system
M3B_RS07485	COG1609	Transcriptional regulator
M3B_RS07500	COG1078	dGTPase activity
M3B_RS07535	COG0772	Belongs to the SEDS family
M3B_RS07545	COG1164	Oligoendopeptidase f
M3B_RS07550	COG0386	Belongs to the glutathione peroxidase family
M3B_RS07600	COG4443	Transcriptional Coactivator p15 (PC4)
M3B_RS07605	COG0826	peptidase U32
M3B_RS07650	COG2183	response to ionizing radiation
M3B_RS07660	COG0701	Predicted permease
M3B_RS07665	COG3689	TIGRFAM TIGR03943 family protein
M3B_RS07675	COG1263	PTS System
M3B_RS07675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3B_RS07675	COG2190	(PTS) system
M3B_RS07680	COG3711	transcriptional antiterminator
M3B_RS07685	COG0477	Major facilitator Superfamily
M3B_RS07690	COG0552	protein localization to endoplasmic reticulum
M3B_RS07695	COG0561	phosphatase activity
M3B_RS07700	COG0561	phosphatase activity
M3B_RS07805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M3B_RS07815	COG1196	nuclear chromosome segregation
M3B_RS07825	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M3B_RS07830	COG5002	protein histidine kinase activity
M3B_RS07835	COG0745	RESPONSE REGULATOR receiver
M3B_RS07850	COG0183	Belongs to the thiolase family
M3B_RS07870	COG4555	ABC transporter
M3B_RS07880	COG0438	transferase activity, transferring glycosyl groups
M3B_RS07890	COG1609	Transcriptional regulator
M3B_RS07895	COG0006	proline dipeptidase activity
M3B_RS07900	COG0778	Nitroreductase
M3B_RS07910	COG0463	Glycosyl transferase, family 2
M3B_RS07940	COG0557	exoribonuclease II activity
M3B_RS07955	COG2814	Major facilitator Superfamily
M3B_RS07960	COG0433	COG0433 Predicted ATPase
M3B_RS08050	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M3B_RS08060	COG1573	uracil-dna glycosylase
M3B_RS08065	COG1702	phosphate starvation-inducible protein PhoH
M3B_RS08155	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M3B_RS08165	COG0494	nUDIX hydrolase
M3B_RS08180	COG0673	inositol 2-dehydrogenase activity
M3B_RS08185	COG1028	Short-chain dehydrogenase reductase Sdr
M3B_RS08250	COG1304	FMN binding
M3B_RS08260	COG0708	Exodeoxyribonuclease III
M3B_RS08265	COG1393	Belongs to the ArsC family
M3B_RS08295	COG0470	DNA polymerase III
M3B_RS08325	COG2244	polysaccharide biosynthetic process
M3B_RS08335	COG1120	ATPase activity
M3B_RS08340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M3B_RS08345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3B_RS08350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M3B_RS08365	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M3B_RS08370	COG1253	flavin adenine dinucleotide binding
M3B_RS08375	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M3B_RS08380	COG1242	4 iron, 4 sulfur cluster binding
M3B_RS08385	COG0671	phosphoesterase, PA-phosphatase related
M3B_RS08390	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M3B_RS08405	COG1187	pseudouridine synthase activity
M3B_RS08460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M3B_RS08465	COG1254	Belongs to the acylphosphatase family
M3B_RS08480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M3B_RS08500	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M3B_RS08510	COG1484	DNA-dependent DNA replication
M3B_RS08530	COG0745	RESPONSE REGULATOR receiver
M3B_RS08545	COG1704	LemA family
M3B_RS08555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M3B_RS08560	COG0569	domain protein
M3B_RS08570	COG1114	Component of the transport system for branched-chain amino acids
M3B_RS08585	COG1464	Belongs to the NlpA lipoprotein family
M3B_RS08590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M3B_RS08610	COG2226	methyltransferase
M3B_RS08615	COG0799	negative regulation of ribosome biogenesis
M3B_RS08620	COG1713	HD superfamily hydrolase involved in NAD metabolism
M3B_RS08630	COG1534	Rna-binding protein
M3B_RS08635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M3B_RS08640	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M3B_RS08650	COG5433	transposase activity
M3B_RS08690	COG1929	Belongs to the glycerate kinase type-1 family
M3B_RS08695	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
M3B_RS08725	COG0577	efflux transmembrane transporter activity
M3B_RS08730	COG1136	(ABC) transporter
M3B_RS08760	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3B_RS08760	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3B_RS08765	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3B_RS08815	COG4974	Belongs to the 'phage' integrase family
M3B_RS08825	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M3B_RS08830	COG1476	TRANSCRIPTIONal
M3B_RS08860	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M3B_RS08880	COG1045	serine acetyltransferase
M3B_RS08895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M3B_RS08910	COG3711	transcriptional antiterminator
M3B_RS08935	COG0431	NADPH-dependent FMN reductase
M3B_RS08940	COG1846	Transcriptional regulator
M3B_RS08960	COG4589	Belongs to the CDS family
M3B_RS08970	COG1862	Preprotein translocase
M3B_RS08980	COG1523	belongs to the glycosyl hydrolase 13 family
M3B_RS08995	COG3842	ATPase activity
M3B_RS09025	COG5433	transposase activity
M3B_RS09040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3B_RS09040	COG1263	PTS System
M3B_RS09040	COG2190	(PTS) system
M3B_RS09045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M3B_RS09060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M3B_RS09065	COG0512	Glutamine amidotransferase of anthranilate synthase
M3B_RS09070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M3B_RS09100	COG0601	transmembrane transport
M3B_RS09130	COG0803	Belongs to the bacterial solute-binding protein 9 family
M3B_RS09140	COG1196	nuclear chromosome segregation
M3B_RS09145	COG3711	transcriptional antiterminator
M3B_RS09160	COG3942	CHAP domain
M3B_RS09160	COG1705	Flagellar rod assembly protein muramidase FlgJ
M3B_RS09165	COG2205	protein histidine kinase activity
M3B_RS09170	COG0745	RESPONSE REGULATOR receiver
M3B_RS09175	COG0577	efflux transmembrane transporter activity
M3B_RS09180	COG1136	(ABC) transporter
M3B_RS09245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M3B_RS09260	COG1882	Formate acetyltransferase
M3B_RS09265	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3B_RS09270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M3B_RS09275	COG1447	Phosphotransferase system cellobiose-specific component IIA
M3B_RS09280	COG2390	Transcriptional regulator
M3B_RS09285	COG1349	DNA-binding transcription factor activity
M3B_RS09290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M3B_RS09310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M3B_RS09325	COG0564	pseudouridine synthase activity
M3B_RS09360	COG0542	response to heat
M3B_RS09365	COG4463	regulation of RNA biosynthetic process
M3B_RS09380	COG0450	alkyl hydroperoxide reductase
M3B_RS09395	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M3B_RS09405	COG3404	Formiminotransferase-cyclodeaminase
M3B_RS09420	COG0531	amino acid
M3B_RS09450	COG3590	peptidase
M3B_RS09455	COG0366	Alpha amylase catalytic
M3B_RS09460	COG1263	PTS System
M3B_RS09460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M3B_RS09465	COG2188	Transcriptional regulator
M3B_RS09475	COG1733	regulation of RNA biosynthetic process
M3B_RS09480	COG2514	catechol 2,3-dioxygenase activity
M3B_RS09490	COG0602	queuosine metabolic process
M3B_RS09510	COG1328	CTP reductase activity
M3B_RS09535	COG1393	Belongs to the ArsC family
M3B_RS09550	COG0519	Catalyzes the synthesis of GMP from XMP
M3B_RS09595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3B_RS09600	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3B_RS09605	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3B_RS09690	COG1511	domain protein
M3B_RS09710	COG0305	Participates in initiation and elongation during chromosome replication
M3B_RS09740	COG1760	l-serine dehydratase
M3B_RS09745	COG1760	l-serine dehydratase
M3B_RS09750	COG0741	lytic transglycosylase activity
M3B_RS09755	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M3B_RS09770	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M3B_RS09780	COG0612	Peptidase, M16
M3B_RS09835	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M3B_RS09840	COG0488	(ABC) transporter
M3B_RS09875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M3B_RS09880	COG1475	DNA binding