locus-tag	class	description
EGC57_RS00010	COG0592	DNA-directed DNA polymerase activity
EGC57_RS00020	COG0012	GTP binding
EGC57_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGC57_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGC57_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGC57_RS00065	COG0531	amino acid
EGC57_RS00245	COG3942	CHAP domain
EGC57_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGC57_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGC57_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGC57_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGC57_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGC57_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGC57_RS00355	COG1454	alcohol dehydrogenase
EGC57_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
EGC57_RS00360	COG1064	alcohol dehydrogenase
EGC57_RS00365	COG0534	Mate efflux family protein
EGC57_RS00475	COG0201	protein transport
EGC57_RS00595	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGC57_RS00620	COG1121	(ABC) transporter
EGC57_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGC57_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGC57_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGC57_RS00665	COG1459	type II secretion system
EGC57_RS00670	COG4537	Required for transformation and DNA binding
EGC57_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGC57_RS00715	COG1363	Peptidase, m42
EGC57_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGC57_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGC57_RS00745	COG1428	Deoxynucleoside kinase
EGC57_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGC57_RS00810	COG2031	fatty acid transporter
EGC57_RS00825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGC57_RS00840	COG0251	oxidation-reduction process
EGC57_RS00855	COG1269	ATP hydrolysis coupled proton transport
EGC57_RS00860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EGC57_RS00870	COG1527	subunit (C
EGC57_RS00875	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EGC57_RS00950	COG0626	cystathionine gamma-synthase activity
EGC57_RS00980	COG3623	hexulose-6-phosphate isomerase
EGC57_RS01005	COG4175	Glycine betaine
EGC57_RS01005	COG3448	diguanylate cyclase activity
EGC57_RS01015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGC57_RS01015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGC57_RS01035	COG3969	phosphoadenosine phosphosulfate
EGC57_RS01040	COG1475	DNA binding
EGC57_RS01060	COG0157	Belongs to the NadC ModD family
EGC57_RS01090	COG1268	BioY protein
EGC57_RS01095	COG1234	tRNA 3'-trailer cleavage
EGC57_RS01130	COG0705	Rhomboid family
EGC57_RS01130	COG0457	Tetratricopeptide repeat
EGC57_RS01150	COG1132	(ABC) transporter
EGC57_RS01155	COG1132	(ABC) transporter
EGC57_RS01165	COG0756	dUTP diphosphatase activity
EGC57_RS01190	COG3290	protein histidine kinase activity
EGC57_RS01215	COG1847	R3H domain protein
EGC57_RS01235	COG1175	transmembrane transport
EGC57_RS01240	COG0395	ABC-type sugar transport system, permease component
EGC57_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGC57_RS01265	COG0084	hydrolase, TatD family'
EGC57_RS01290	COG1564	THIamine pyrophosphokinase
EGC57_RS01305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGC57_RS01345	COG0765	amino acid transport
EGC57_RS01365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGC57_RS01375	COG0719	Fe-S assembly protein
EGC57_RS01380	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGC57_RS01395	COG1686	Belongs to the peptidase S11 family
EGC57_RS01400	COG1686	Belongs to the peptidase S11 family
EGC57_RS01405	COG4166	transmembrane transport
EGC57_RS01410	COG0601	transmembrane transport
EGC57_RS01415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGC57_RS01420	COG0444	Belongs to the ABC transporter superfamily
EGC57_RS01430	COG2801	Transposase and inactivated derivatives
EGC57_RS01440	COG2801	Transposase and inactivated derivatives
EGC57_RS01445	COG2801	Transposase and inactivated derivatives
EGC57_RS01450	COG2801	Transposase and inactivated derivatives
EGC57_RS01495	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EGC57_RS01500	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EGC57_RS01505	COG1534	Rna-binding protein
EGC57_RS01515	COG1713	HD superfamily hydrolase involved in NAD metabolism
EGC57_RS01520	COG0799	negative regulation of ribosome biogenesis
EGC57_RS01525	COG2226	methyltransferase
EGC57_RS01545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGC57_RS01550	COG1464	Belongs to the NlpA lipoprotein family
EGC57_RS01565	COG1114	Component of the transport system for branched-chain amino acids
EGC57_RS01575	COG0569	domain protein
EGC57_RS01580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGC57_RS01590	COG1704	LemA family
EGC57_RS01605	COG0745	RESPONSE REGULATOR receiver
EGC57_RS01610	COG5002	protein histidine kinase activity
EGC57_RS01625	COG1484	DNA-dependent DNA replication
EGC57_RS01635	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGC57_RS01655	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGC57_RS01670	COG1254	Belongs to the acylphosphatase family
EGC57_RS01675	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGC57_RS01730	COG1187	pseudouridine synthase activity
EGC57_RS01745	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EGC57_RS01750	COG0671	phosphoesterase, PA-phosphatase related
EGC57_RS01755	COG1242	4 iron, 4 sulfur cluster binding
EGC57_RS01760	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EGC57_RS01765	COG1253	flavin adenine dinucleotide binding
EGC57_RS01770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGC57_RS01785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGC57_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGC57_RS01795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGC57_RS01800	COG1120	ATPase activity
EGC57_RS01810	COG2244	polysaccharide biosynthetic process
EGC57_RS01840	COG0470	DNA polymerase III
EGC57_RS01870	COG1393	Belongs to the ArsC family
EGC57_RS01885	COG1609	Transcriptional regulator
EGC57_RS01890	COG0561	phosphatase activity
EGC57_RS01895	COG0708	Exodeoxyribonuclease III
EGC57_RS01905	COG1304	FMN binding
EGC57_RS02000	COG1028	Short-chain dehydrogenase reductase Sdr
EGC57_RS02005	COG0673	inositol 2-dehydrogenase activity
EGC57_RS02020	COG0494	nUDIX hydrolase
EGC57_RS02030	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGC57_RS02120	COG1702	phosphate starvation-inducible protein PhoH
EGC57_RS02125	COG1573	uracil-dna glycosylase
EGC57_RS02135	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGC57_RS02225	COG0433	COG0433 Predicted ATPase
EGC57_RS02230	COG2814	Major facilitator Superfamily
EGC57_RS02245	COG0557	exoribonuclease II activity
EGC57_RS02275	COG0463	Glycosyl transferase, family 2
EGC57_RS02285	COG0778	Nitroreductase
EGC57_RS02290	COG0006	proline dipeptidase activity
EGC57_RS02295	COG1609	Transcriptional regulator
EGC57_RS02305	COG0438	transferase activity, transferring glycosyl groups
EGC57_RS02315	COG4555	ABC transporter
EGC57_RS02335	COG0183	Belongs to the thiolase family
EGC57_RS02350	COG0745	RESPONSE REGULATOR receiver
EGC57_RS02355	COG5002	protein histidine kinase activity
EGC57_RS02360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGC57_RS02370	COG1196	nuclear chromosome segregation
EGC57_RS02380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGC57_RS02480	COG0561	phosphatase activity
EGC57_RS02485	COG0561	phosphatase activity
EGC57_RS02490	COG0552	protein localization to endoplasmic reticulum
EGC57_RS02495	COG0477	Major facilitator Superfamily
EGC57_RS02500	COG3711	transcriptional antiterminator
EGC57_RS02505	COG1263	PTS System
EGC57_RS02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGC57_RS02505	COG2190	(PTS) system
EGC57_RS02515	COG3689	TIGRFAM TIGR03943 family protein
EGC57_RS02520	COG0701	Predicted permease
EGC57_RS02530	COG2183	response to ionizing radiation
EGC57_RS02575	COG0826	peptidase U32
EGC57_RS02580	COG4443	Transcriptional Coactivator p15 (PC4)
EGC57_RS02605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGC57_RS02630	COG0386	Belongs to the glutathione peroxidase family
EGC57_RS02635	COG1164	Oligoendopeptidase f
EGC57_RS02645	COG0772	Belongs to the SEDS family
EGC57_RS02680	COG1078	dGTPase activity
EGC57_RS02695	COG1609	Transcriptional regulator
EGC57_RS02705	COG3716	PTS system mannose fructose sorbose family IID component
EGC57_RS02710	COG3715	PTS system
EGC57_RS02715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGC57_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
EGC57_RS02745	COG0800	Aldolase
EGC57_RS02750	COG0546	phosphoglycolate phosphatase activity
EGC57_RS02755	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGC57_RS02765	COG2884	Cell division ATP-binding protein ftsE
EGC57_RS02770	COG2177	Part of the ABC transporter FtsEX involved in
EGC57_RS02785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGC57_RS02785	COG1199	ATP-dependent helicase activity
EGC57_RS02790	COG0436	Aminotransferase
EGC57_RS02825	COG2188	Transcriptional regulator
EGC57_RS02830	COG2222	sugar isomerase
EGC57_RS02840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EGC57_RS02845	COG0716	FMN binding
EGC57_RS02855	COG0038	chloride channel
EGC57_RS02930	COG1131	(ABC) transporter
EGC57_RS02955	COG4708	membrane
EGC57_RS02965	COG1597	lipid kinase activity
EGC57_RS03050	COG0577	efflux transmembrane transporter activity
EGC57_RS03060	COG2321	neutral zinc metallopeptidase
EGC57_RS03075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGC57_RS03085	COG1970	mechanosensitive ion channel activity
EGC57_RS03090	COG0358	DNA primase activity
EGC57_RS03095	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGC57_RS03100	COG2151	metal-sulfur cluster biosynthetic enzyme
EGC57_RS03145	COG1216	Glycosyl transferase, family 2
EGC57_RS03205	COG1368	sulfuric ester hydrolase activity
EGC57_RS03210	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EGC57_RS03230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGC57_RS03235	COG0285	dihydrofolate synthase activity
EGC57_RS03245	COG1104	cysteine desulfurase activity
EGC57_RS03270	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EGC57_RS03280	COG0583	DNA-binding transcription factor activity
EGC57_RS03290	COG0564	pseudouridine synthase activity
EGC57_RS03295	COG5433	transposase activity
EGC57_RS03335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGC57_RS03340	COG1136	(ABC) transporter
EGC57_RS03345	COG0577	efflux transmembrane transporter activity
EGC57_RS03350	COG0584	glycerophosphoryl diester phosphodiesterase
EGC57_RS03360	COG1837	Belongs to the UPF0109 family
EGC57_RS03410	COG1349	DNA-binding transcription factor activity
EGC57_RS03415	COG1105	Belongs to the carbohydrate kinase PfkB family
EGC57_RS03420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGC57_RS03420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGC57_RS03420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGC57_RS03425	COG3942	CHAP domain
EGC57_RS03425	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGC57_RS03430	COG1388	LysM domain
EGC57_RS03430	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGC57_RS03470	COG0488	(ABC) transporter
EGC57_RS03485	COG0242	peptide deformylase activity
EGC57_RS03490	COG0737	Belongs to the 5'-nucleotidase family
EGC57_RS03495	COG2357	RelA SpoT domain protein
EGC57_RS03500	COG0745	RESPONSE REGULATOR receiver
EGC57_RS03535	COG3425	synthase
EGC57_RS03545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGC57_RS03605	COG0583	DNA-binding transcription factor activity
EGC57_RS03630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGC57_RS03635	COG0765	amino acid transport
EGC57_RS03655	COG0187	DNA topoisomerase II activity
EGC57_RS03665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGC57_RS03685	COG0539	negative regulation of cytoplasmic translation
EGC57_RS03730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGC57_RS03735	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EGC57_RS03745	COG0300	oxidoreductase activity
EGC57_RS03750	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EGC57_RS03750	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGC57_RS03765	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGC57_RS03770	COG2384	SAM-dependent methyltransferase
EGC57_RS03780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGC57_RS03785	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGC57_RS03795	COG1088	dTDP-glucose 4,6-dehydratase activity
EGC57_RS03800	COG0582	viral genome integration into host DNA
EGC57_RS03910	COG1783	phage Terminase large subunit
EGC57_RS04055	COG1051	belongs to the nudix hydrolase family
EGC57_RS04060	COG0628	permease
EGC57_RS04065	COG0457	Tetratricopeptide repeat
EGC57_RS04070	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EGC57_RS04090	COG1129	ABC transporter
EGC57_RS04110	COG0488	(ABC) transporter
EGC57_RS04115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGC57_RS04120	COG0022	dehydrogenase e1 component
EGC57_RS04120	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGC57_RS04125	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGC57_RS04140	COG1695	Transcriptional regulator
EGC57_RS04150	COG0095	Lipoate-protein ligase
EGC57_RS04155	COG3442	glutamine amidotransferase
EGC57_RS04160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGC57_RS04165	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EGC57_RS04185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGC57_RS04195	COG0647	UMP catabolic process
EGC57_RS04210	COG0105	UTP biosynthetic process
EGC57_RS04245	COG3715	PTS system
EGC57_RS04250	COG3716	PTS system mannose fructose sorbose family IID component
EGC57_RS04255	COG2972	Histidine kinase
EGC57_RS04260	COG4753	response regulator
EGC57_RS04260	COG2207	Transcriptional regulator
EGC57_RS04270	COG1012	belongs to the aldehyde dehydrogenase family
EGC57_RS04285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGC57_RS04360	COG1131	(ABC) transporter
EGC57_RS04405	COG0285	dihydrofolate synthase activity
EGC57_RS04425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGC57_RS04440	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGC57_RS04445	COG1177	transmembrane transport
EGC57_RS04455	COG4565	transcriptional regulatory protein
EGC57_RS04460	COG3290	protein histidine kinase activity
EGC57_RS04465	COG3493	citrate carrier protein
EGC57_RS04480	COG3700	Belongs to the class B bacterial acid phosphatase family
EGC57_RS04485	COG0038	chloride channel
EGC57_RS04495	COG0628	permease
EGC57_RS04505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EGC57_RS04520	COG1104	cysteine desulfurase activity
EGC57_RS04535	COG2357	RelA SpoT domain protein
EGC57_RS04545	COG0564	pseudouridine synthase activity
EGC57_RS04550	COG0280	phosphate acetyltransferase
EGC57_RS04555	COG4221	oxidoreductase activity
EGC57_RS04570	COG1174	glycine betaine transport
EGC57_RS04590	COG2233	PERMEase
EGC57_RS04615	COG2890	protein-(glutamine-N5) methyltransferase activity
EGC57_RS04645	COG1132	(ABC) transporter
EGC57_RS04650	COG1132	(ABC) transporter
EGC57_RS04670	COG3764	Sortase (surface protein transpeptidase)
EGC57_RS04675	COG0346	lactoylglutathione lyase activity
EGC57_RS04695	COG1272	protein, Hemolysin III
EGC57_RS04715	COG0758	DNA mediated transformation
EGC57_RS04720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGC57_RS04770	COG0511	ligase activity, forming carbon-carbon bonds
EGC57_RS04775	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EGC57_RS04790	COG2851	Citrate transporter
EGC57_RS04800	COG0511	ligase activity, forming carbon-carbon bonds
EGC57_RS04805	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EGC57_RS04835	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EGC57_RS04855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGC57_RS04865	COG2188	Transcriptional regulator
EGC57_RS04885	COG0488	(ABC) transporter
EGC57_RS04895	COG0351	phosphomethylpyrimidine kinase
EGC57_RS04895	COG0352	thiamine-phosphate diphosphorylase activity
EGC57_RS04900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGC57_RS04910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EGC57_RS04910	COG1328	CTP reductase activity
EGC57_RS04915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGC57_RS04945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGC57_RS04955	COG0095	Lipoate-protein ligase
EGC57_RS04965	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGC57_RS04970	COG4684	Psort location CytoplasmicMembrane, score
EGC57_RS04975	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGC57_RS04980	COG1079	Belongs to the binding-protein-dependent transport system permease family
EGC57_RS04985	COG4603	Belongs to the binding-protein-dependent transport system permease family
EGC57_RS04990	COG3845	ABC transporter
EGC57_RS04995	COG1744	ABC transporter substrate-binding protein PnrA-like
EGC57_RS05000	COG0295	cytidine deaminase activity
EGC57_RS05005	COG2813	Specifically methylates the guanine in position
EGC57_RS05020	COG5002	protein histidine kinase activity
EGC57_RS05025	COG0745	RESPONSE REGULATOR receiver
EGC57_RS05035	COG0704	Plays a role in the regulation of phosphate uptake
EGC57_RS05050	COG0581	inorganic phosphate transmembrane transporter activity
EGC57_RS05055	COG0573	inorganic phosphate transmembrane transporter activity
EGC57_RS05065	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EGC57_RS05065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGC57_RS05070	COG0483	inositol monophosphate 1-phosphatase activity
EGC57_RS05085	COG0196	riboflavin kinase activity
EGC57_RS05115	COG1136	(ABC) transporter
EGC57_RS05115	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGC57_RS05165	COG1115	amino acid carrier protein
EGC57_RS05170	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EGC57_RS05180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGC57_RS05185	COG1126	abc transporter atp-binding protein
EGC57_RS05190	COG0765	amino acid transport
EGC57_RS05195	COG2824	Alkylphosphonate utilization operon protein PhnA
EGC57_RS05210	COG0469	pyruvate kinase activity
EGC57_RS05225	COG1725	Transcriptional regulator
EGC57_RS05230	COG1131	(ABC) transporter
EGC57_RS05255	COG0058	SHG alpha-glucan phosphorylase activity
EGC57_RS05260	COG1640	4-alpha-glucanotransferase
EGC57_RS05265	COG1609	Transcriptional regulator
EGC57_RS05270	COG2182	Extracellular solute-binding protein
EGC57_RS05275	COG1175	transmembrane transport
EGC57_RS05280	COG3833	ABC-type maltose transport systems, permease component
EGC57_RS05295	COG3833	ABC-type maltose transport systems, permease component
EGC57_RS05300	COG1175	transmembrane transport
EGC57_RS05310	COG0366	Alpha amylase catalytic
EGC57_RS05315	COG2182	Extracellular solute-binding protein
EGC57_RS05325	COG0657	acetylesterase activity
EGC57_RS05330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EGC57_RS05340	COG1696	Membrane protein involved in D-alanine export
EGC57_RS05360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGC57_RS05365	COG1126	abc transporter atp-binding protein
EGC57_RS05370	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGC57_RS05380	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGC57_RS05390	COG3711	transcriptional antiterminator
EGC57_RS05390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGC57_RS05400	COG2723	6-phospho-beta-galactosidase activity
EGC57_RS05430	COG1187	pseudouridine synthase activity
EGC57_RS05440	COG2814	Major facilitator Superfamily
EGC57_RS05490	COG4109	DRTGG domain
EGC57_RS05495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGC57_RS05525	COG1028	Short-chain dehydrogenase reductase Sdr
EGC57_RS05540	COG0800	Aldolase
EGC57_RS05545	COG2186	Transcriptional regulator
EGC57_RS05550	COG3250	beta-galactosidase activity
EGC57_RS05560	COG2211	Major facilitator Superfamily
EGC57_RS05580	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EGC57_RS05580	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EGC57_RS05590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGC57_RS05595	COG1956	GAF domain-containing protein
EGC57_RS05615	COG0513	Belongs to the DEAD box helicase family
EGC57_RS05620	COG0726	polysaccharide deacetylase
EGC57_RS05640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGC57_RS05645	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGC57_RS05680	COG1476	TRANSCRIPTIONal
EGC57_RS05695	COG4122	O-methyltransferase activity
EGC57_RS05700	COG2223	nitrite transmembrane transporter activity
EGC57_RS05715	COG1187	pseudouridine synthase activity
EGC57_RS05755	COG2333	competence protein COMEC
EGC57_RS05755	COG0658	competence protein
EGC57_RS05760	COG1596	polysaccharide export
EGC57_RS05760	COG1555	photosystem II stabilization
EGC57_RS05765	COG0204	Acyl-transferase
EGC57_RS05770	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EGC57_RS05785	COG0513	Belongs to the DEAD box helicase family
EGC57_RS05805	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGC57_RS05820	COG0768	penicillin binding
EGC57_RS05825	COG2116	formate transmembrane transporter activity
EGC57_RS05835	COG1827	regulation of RNA biosynthetic process
EGC57_RS05850	COG2217	Heavy metal translocating P-type atpase
EGC57_RS05880	COG1388	LysM domain
EGC57_RS05880	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGC57_RS05890	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGC57_RS06140	COG0582	viral genome integration into host DNA
EGC57_RS06155	COG2755	lipolytic protein G-D-S-L family
EGC57_RS06170	COG0497	DNA recombination
EGC57_RS06175	COG1438	arginine binding
EGC57_RS06180	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EGC57_RS06205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGC57_RS06210	COG0415	Belongs to the DNA photolyase family
EGC57_RS06220	COG0765	amino acid transport
EGC57_RS06225	COG4703	Protein of unknown function (DUF1797)
EGC57_RS06230	COG0542	response to heat
EGC57_RS06235	COG0494	nUDIX hydrolase
EGC57_RS06250	COG3599	regulation of cell shape
EGC57_RS06255	COG2302	S4 RNA-binding domain
EGC57_RS06270	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGC57_RS06305	COG1217	gtp-binding protein TYPA
EGC57_RS06310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGC57_RS06315	COG1940	carbohydrate kinase activity
EGC57_RS06325	COG0783	Belongs to the Dps family
EGC57_RS06340	COG4470	Protein conserved in bacteria
EGC57_RS06345	COG1609	Transcriptional regulator
EGC57_RS06350	COG3480	Lon protease (S16) C-terminal proteolytic domain
EGC57_RS06360	COG0742	ribosomal rna small subunit methyltransferase
EGC57_RS06370	COG0549	Belongs to the carbamate kinase family
EGC57_RS06375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EGC57_RS06380	COG1288	antiporter activity
EGC57_RS06395	COG2235	arginine
EGC57_RS06420	COG2972	Histidine kinase
EGC57_RS06435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGC57_RS06440	COG0785	Cytochrome C biogenesis protein
EGC57_RS06445	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EGC57_RS06450	COG1518	maintenance of DNA repeat elements
EGC57_RS06515	COG1605	Chorismate mutase
EGC57_RS06515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EGC57_RS06535	COG2226	methyltransferase
EGC57_RS06545	COG3250	beta-galactosidase activity
EGC57_RS06550	COG2207	Transcriptional regulator
EGC57_RS06550	COG4753	response regulator
EGC57_RS06555	COG2972	Histidine kinase
EGC57_RS06565	COG1653	transport
EGC57_RS06570	COG0395	ABC-type sugar transport system, permease component
EGC57_RS06575	COG1175	transmembrane transport
EGC57_RS06580	COG1940	carbohydrate kinase activity
EGC57_RS06585	COG2723	6-phospho-beta-galactosidase activity
EGC57_RS06590	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EGC57_RS06605	COG0383	alpha-mannosidase activity
EGC57_RS06715	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EGC57_RS06720	COG1739	Uncharacterized protein family UPF0029
EGC57_RS06730	COG1098	S1 RNA binding domain
EGC57_RS06740	COG2197	response regulator
EGC57_RS06745	COG4585	Histidine kinase
EGC57_RS06755	COG0515	serine threonine protein kinase
EGC57_RS06755	COG2815	serine threonine protein kinase
EGC57_RS06765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EGC57_RS06765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EGC57_RS06775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGC57_RS06795	COG0583	DNA-binding transcription factor activity
EGC57_RS06800	COG0183	Belongs to the thiolase family
EGC57_RS06805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGC57_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
EGC57_RS06820	COG2610	gluconate transmembrane transporter activity
EGC57_RS06835	COG0116	Belongs to the methyltransferase superfamily
EGC57_RS06860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGC57_RS06865	COG3579	cysteine-type endopeptidase activity
EGC57_RS06875	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EGC57_RS06880	COG1113	amino acid transport
EGC57_RS06885	COG0492	ferredoxin-NADP+ reductase activity
EGC57_RS06895	COG1126	abc transporter atp-binding protein
EGC57_RS06905	COG0513	Belongs to the DEAD box helicase family
EGC57_RS06915	COG0768	penicillin binding
EGC57_RS06950	COG1131	(ABC) transporter
EGC57_RS06975	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGC57_RS06980	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGC57_RS07020	COG1755	Isoprenylcysteine carboxyl methyltransferase
EGC57_RS07035	COG1283	sodium-dependent phosphate transmembrane transporter activity
EGC57_RS07055	COG0561	phosphatase activity
EGC57_RS07060	COG2860	membrane
EGC57_RS07120	COG2217	Heavy metal translocating P-type atpase
EGC57_RS07150	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EGC57_RS07155	COG0195	Participates in both transcription termination and antitermination
EGC57_RS07180	COG4473	ABC transporter
EGC57_RS07185	COG1131	(ABC) transporter
EGC57_RS07190	COG0537	adenosine 5'-monophosphoramidase activity
EGC57_RS07200	COG1316	TRANSCRIPTIONal
EGC57_RS07210	COG0802	atpase or kinase
EGC57_RS07215	COG2252	PERMEase
EGC57_RS07220	COG0561	phosphatase activity
EGC57_RS07230	COG3715	PTS system
EGC57_RS07235	COG3716	PTS system mannose fructose sorbose family IID component
EGC57_RS07260	COG0439	Biotin carboxylase
EGC57_RS07275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGC57_RS07280	COG1028	Short-chain dehydrogenase reductase Sdr
EGC57_RS07285	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGC57_RS07310	COG1024	Enoyl-CoA hydratase
EGC57_RS07315	COG0484	heat shock protein binding
EGC57_RS07345	COG0588	phosphoglycerate mutase activity
EGC57_RS07350	COG2261	transglycosylase associated protein
EGC57_RS07385	COG1335	isochorismatase
EGC57_RS07395	COG0436	Aminotransferase
EGC57_RS07405	COG0561	phosphatase activity
EGC57_RS07410	COG0252	asparaginase activity
EGC57_RS07425	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGC57_RS07435	COG1129	ABC transporter
EGC57_RS07450	COG1132	(ABC) transporter
EGC57_RS07455	COG4988	ABC transporter
EGC57_RS07460	COG1120	ATPase activity
EGC57_RS07485	COG3942	CHAP domain
EGC57_RS07485	COG1388	LysM domain
EGC57_RS07510	COG5433	transposase activity
EGC57_RS07515	COG1482	cell wall glycoprotein biosynthetic process
EGC57_RS07520	COG1940	carbohydrate kinase activity
EGC57_RS07530	COG2190	(PTS) system
EGC57_RS07530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGC57_RS07530	COG1263	PTS System
EGC57_RS07535	COG1621	beta-fructofuranosidase activity
EGC57_RS07540	COG1609	Transcriptional regulator
EGC57_RS07560	COG2131	deaminase
EGC57_RS07565	COG0006	proline dipeptidase activity
EGC57_RS07595	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGC57_RS07600	COG4824	toxin secretion phage lysis holin
EGC57_RS07735	COG1475	DNA binding
EGC57_RS07805	COG3723	Recombinational DNA repair protein, rece pathway
EGC57_RS07865	COG3561	AntA/AntB antirepressor
EGC57_RS07875	COG1396	sequence-specific DNA binding
EGC57_RS07925	COG1194	a g-specific adenine glycosylase
EGC57_RS07935	COG3118	belongs to the thioredoxin family
EGC57_RS07965	COG0681	Belongs to the peptidase S26 family
EGC57_RS07970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGC57_RS07985	COG1882	Formate acetyltransferase
EGC57_RS07990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGC57_RS08005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGC57_RS08015	COG2814	Major facilitator Superfamily
EGC57_RS08020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGC57_RS08045	COG0789	Transcriptional regulator
EGC57_RS08080	COG2081	HI0933 family
EGC57_RS08090	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGC57_RS08095	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EGC57_RS08115	COG0456	acetyltransferase
EGC57_RS08120	COG1214	PFAM Peptidase M22, glycoprotease
EGC57_RS08135	COG0174	glutamine synthetase
EGC57_RS08140	COG0789	Transcriptional regulator
EGC57_RS08155	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EGC57_RS08210	COG0668	transmembrane transport
EGC57_RS08220	COG4720	Psort location CytoplasmicMembrane, score
EGC57_RS08225	COG0351	phosphomethylpyrimidine kinase
EGC57_RS08270	COG1929	Belongs to the glycerate kinase type-1 family
EGC57_RS08275	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGC57_RS08305	COG0577	efflux transmembrane transporter activity
EGC57_RS08310	COG1136	(ABC) transporter
EGC57_RS08335	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGC57_RS08335	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGC57_RS08340	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGC57_RS08395	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EGC57_RS08400	COG1476	TRANSCRIPTIONal
EGC57_RS08420	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGC57_RS08430	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EGC57_RS08450	COG1045	serine acetyltransferase
EGC57_RS08465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGC57_RS08480	COG3711	transcriptional antiterminator
EGC57_RS08505	COG0431	NADPH-dependent FMN reductase
EGC57_RS08510	COG1846	Transcriptional regulator
EGC57_RS08530	COG4589	Belongs to the CDS family
EGC57_RS08540	COG1862	Preprotein translocase
EGC57_RS08550	COG1523	belongs to the glycosyl hydrolase 13 family
EGC57_RS08565	COG3842	ATPase activity
EGC57_RS08605	COG2190	(PTS) system
EGC57_RS08605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGC57_RS08605	COG1263	PTS System
EGC57_RS08610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGC57_RS08630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGC57_RS08635	COG0512	Glutamine amidotransferase of anthranilate synthase
EGC57_RS08640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGC57_RS08670	COG0601	transmembrane transport
EGC57_RS08675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGC57_RS08680	COG1122	ATPase activity
EGC57_RS08700	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGC57_RS08710	COG1404	Belongs to the peptidase S8 family
EGC57_RS08710	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGC57_RS08730	COG3711	transcriptional antiterminator
EGC57_RS08745	COG1705	Flagellar rod assembly protein muramidase FlgJ
EGC57_RS08745	COG3942	CHAP domain
EGC57_RS08750	COG2205	protein histidine kinase activity
EGC57_RS08755	COG0745	RESPONSE REGULATOR receiver
EGC57_RS08760	COG0577	efflux transmembrane transporter activity
EGC57_RS08765	COG1136	(ABC) transporter
EGC57_RS08840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGC57_RS08855	COG1882	Formate acetyltransferase
EGC57_RS08860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGC57_RS08865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGC57_RS08870	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGC57_RS08875	COG2390	Transcriptional regulator
EGC57_RS08880	COG1349	DNA-binding transcription factor activity
EGC57_RS08885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGC57_RS08905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGC57_RS08920	COG0564	pseudouridine synthase activity
EGC57_RS08955	COG0542	response to heat
EGC57_RS08960	COG4463	regulation of RNA biosynthetic process
EGC57_RS08975	COG0450	alkyl hydroperoxide reductase
EGC57_RS08990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EGC57_RS09000	COG3404	Formiminotransferase-cyclodeaminase
EGC57_RS09015	COG0531	amino acid
EGC57_RS09045	COG3590	peptidase
EGC57_RS09050	COG0366	Alpha amylase catalytic
EGC57_RS09055	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGC57_RS09055	COG1263	PTS System
EGC57_RS09060	COG2188	Transcriptional regulator
EGC57_RS09070	COG1733	regulation of RNA biosynthetic process
EGC57_RS09075	COG2514	catechol 2,3-dioxygenase activity
EGC57_RS09085	COG0602	queuosine metabolic process
EGC57_RS09100	COG1328	CTP reductase activity
EGC57_RS09125	COG1393	Belongs to the ArsC family
EGC57_RS09140	COG0519	Catalyzes the synthesis of GMP from XMP
EGC57_RS09185	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGC57_RS09190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGC57_RS09195	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGC57_RS09280	COG1511	domain protein
EGC57_RS09300	COG0305	Participates in initiation and elongation during chromosome replication
EGC57_RS09330	COG1760	l-serine dehydratase
EGC57_RS09335	COG1760	l-serine dehydratase
EGC57_RS09340	COG0741	lytic transglycosylase activity
EGC57_RS09345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EGC57_RS09360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGC57_RS09370	COG0612	Peptidase, M16
EGC57_RS09415	COG0516	GMP reductase activity
EGC57_RS09415	COG0517	IMP dehydrogenase activity
EGC57_RS09425	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EGC57_RS09430	COG0488	(ABC) transporter
EGC57_RS09475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGC57_RS09480	COG1475	DNA binding