locus-tag	class	description
AWM58_RS00010	COG0592	DNA-directed DNA polymerase activity
AWM58_RS00020	COG0012	GTP binding
AWM58_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AWM58_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AWM58_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AWM58_RS00065	COG0531	amino acid
AWM58_RS00180	COG3942	CHAP domain
AWM58_RS00200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AWM58_RS00210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AWM58_RS00225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AWM58_RS00245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AWM58_RS00265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AWM58_RS00280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AWM58_RS00295	COG1012	belongs to the aldehyde dehydrogenase family
AWM58_RS00295	COG1454	alcohol dehydrogenase
AWM58_RS00300	COG1064	alcohol dehydrogenase
AWM58_RS00415	COG0201	protein transport
AWM58_RS00560	COG1121	(ABC) transporter
AWM58_RS00565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AWM58_RS00600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AWM58_RS00605	COG1459	type II secretion system
AWM58_RS00610	COG4537	Required for transformation and DNA binding
AWM58_RS00650	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AWM58_RS00655	COG1363	Peptidase, m42
AWM58_RS00665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM58_RS00670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AWM58_RS00680	COG1428	Deoxynucleoside kinase
AWM58_RS00685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AWM58_RS00740	COG2031	fatty acid transporter
AWM58_RS00755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWM58_RS00770	COG0251	oxidation-reduction process
AWM58_RS00785	COG1269	ATP hydrolysis coupled proton transport
AWM58_RS00790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AWM58_RS00800	COG1527	subunit (C
AWM58_RS00805	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
AWM58_RS00840	COG1744	ABC transporter substrate-binding protein PnrA-like
AWM58_RS00880	COG0626	cystathionine gamma-synthase activity
AWM58_RS00910	COG3623	hexulose-6-phosphate isomerase
AWM58_RS00930	COG4175	Glycine betaine
AWM58_RS00930	COG3448	diguanylate cyclase activity
AWM58_RS00940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWM58_RS00940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AWM58_RS00965	COG1268	BioY protein
AWM58_RS00970	COG1234	tRNA 3'-trailer cleavage
AWM58_RS01015	COG0457	Tetratricopeptide repeat
AWM58_RS01015	COG0705	Rhomboid family
AWM58_RS01035	COG1132	(ABC) transporter
AWM58_RS01040	COG1132	(ABC) transporter
AWM58_RS01050	COG0756	dUTP diphosphatase activity
AWM58_RS01100	COG1847	R3H domain protein
AWM58_RS01120	COG1175	transmembrane transport
AWM58_RS01125	COG0395	ABC-type sugar transport system, permease component
AWM58_RS01140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AWM58_RS01180	COG1564	THIamine pyrophosphokinase
AWM58_RS01195	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AWM58_RS01230	COG0765	amino acid transport
AWM58_RS01250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AWM58_RS01260	COG0719	Fe-S assembly protein
AWM58_RS01265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AWM58_RS01280	COG1686	Belongs to the peptidase S11 family
AWM58_RS01285	COG1686	Belongs to the peptidase S11 family
AWM58_RS01290	COG4166	transmembrane transport
AWM58_RS01295	COG0601	transmembrane transport
AWM58_RS01300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AWM58_RS01305	COG0444	Belongs to the ABC transporter superfamily
AWM58_RS01355	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
AWM58_RS01365	COG1534	Rna-binding protein
AWM58_RS01375	COG1713	HD superfamily hydrolase involved in NAD metabolism
AWM58_RS01385	COG0799	negative regulation of ribosome biogenesis
AWM58_RS01390	COG2226	methyltransferase
AWM58_RS01405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM58_RS01410	COG1464	Belongs to the NlpA lipoprotein family
AWM58_RS01425	COG1114	Component of the transport system for branched-chain amino acids
AWM58_RS01435	COG0569	domain protein
AWM58_RS01440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AWM58_RS01450	COG1704	LemA family
AWM58_RS01465	COG0745	RESPONSE REGULATOR receiver
AWM58_RS01485	COG1484	DNA-dependent DNA replication
AWM58_RS01495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AWM58_RS01515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AWM58_RS01530	COG1254	Belongs to the acylphosphatase family
AWM58_RS01535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWM58_RS01590	COG1187	pseudouridine synthase activity
AWM58_RS01605	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AWM58_RS01610	COG0671	phosphoesterase, PA-phosphatase related
AWM58_RS01615	COG1242	4 iron, 4 sulfur cluster binding
AWM58_RS01620	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AWM58_RS01625	COG1253	flavin adenine dinucleotide binding
AWM58_RS01630	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AWM58_RS01645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM58_RS01650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AWM58_RS01655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AWM58_RS01680	COG2244	polysaccharide biosynthetic process
AWM58_RS01705	COG0470	DNA polymerase III
AWM58_RS01735	COG1393	Belongs to the ArsC family
AWM58_RS01740	COG0708	Exodeoxyribonuclease III
AWM58_RS01750	COG1304	FMN binding
AWM58_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
AWM58_RS01840	COG0673	inositol 2-dehydrogenase activity
AWM58_RS01855	COG0494	nUDIX hydrolase
AWM58_RS01865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AWM58_RS01955	COG1702	phosphate starvation-inducible protein PhoH
AWM58_RS01960	COG1573	uracil-dna glycosylase
AWM58_RS01970	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AWM58_RS01985	COG2274	protein secretion by the type I secretion system
AWM58_RS01990	COG2274	protein secretion by the type I secretion system
AWM58_RS02025	COG2801	Transposase and inactivated derivatives
AWM58_RS02115	COG0433	COG0433 Predicted ATPase
AWM58_RS02130	COG0557	exoribonuclease II activity
AWM58_RS02160	COG0463	Glycosyl transferase, family 2
AWM58_RS02175	COG0006	proline dipeptidase activity
AWM58_RS02180	COG1609	Transcriptional regulator
AWM58_RS02200	COG4555	ABC transporter
AWM58_RS02225	COG2376	Dihydroxyacetone kinase
AWM58_RS02230	COG1461	Dihydroxyacetone kinase
AWM58_RS02235	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
AWM58_RS02240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWM58_RS02250	COG0183	Belongs to the thiolase family
AWM58_RS02265	COG0745	RESPONSE REGULATOR receiver
AWM58_RS02270	COG5002	protein histidine kinase activity
AWM58_RS02275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AWM58_RS02285	COG1196	nuclear chromosome segregation
AWM58_RS02295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AWM58_RS02405	COG1619	proteins homologs of microcin C7 resistance protein MccF
AWM58_RS02420	COG0561	phosphatase activity
AWM58_RS02425	COG0561	phosphatase activity
AWM58_RS02430	COG0552	protein localization to endoplasmic reticulum
AWM58_RS02435	COG0477	Major facilitator Superfamily
AWM58_RS02440	COG3711	transcriptional antiterminator
AWM58_RS02455	COG3689	TIGRFAM TIGR03943 family protein
AWM58_RS02460	COG0701	Predicted permease
AWM58_RS02470	COG2183	response to ionizing radiation
AWM58_RS02515	COG0826	peptidase U32
AWM58_RS02520	COG4443	Transcriptional Coactivator p15 (PC4)
AWM58_RS02565	COG0386	Belongs to the glutathione peroxidase family
AWM58_RS02570	COG1164	Oligoendopeptidase f
AWM58_RS02580	COG0772	Belongs to the SEDS family
AWM58_RS02615	COG1078	dGTPase activity
AWM58_RS02630	COG1609	Transcriptional regulator
AWM58_RS02640	COG3716	PTS system mannose fructose sorbose family IID component
AWM58_RS02645	COG3715	PTS system
AWM58_RS02665	COG1028	Short-chain dehydrogenase reductase Sdr
AWM58_RS02680	COG0800	Aldolase
AWM58_RS02685	COG0546	phosphoglycolate phosphatase activity
AWM58_RS02690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AWM58_RS02700	COG2884	Cell division ATP-binding protein ftsE
AWM58_RS02705	COG2177	Part of the ABC transporter FtsEX involved in
AWM58_RS02720	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AWM58_RS02720	COG1199	ATP-dependent helicase activity
AWM58_RS02725	COG0436	Aminotransferase
AWM58_RS02805	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWM58_RS02840	COG2188	Transcriptional regulator
AWM58_RS02845	COG2222	sugar isomerase
AWM58_RS02860	COG0716	FMN binding
AWM58_RS02870	COG0038	chloride channel
AWM58_RS02960	COG1131	(ABC) transporter
AWM58_RS02980	COG4708	membrane
AWM58_RS02990	COG1597	lipid kinase activity
AWM58_RS03075	COG0577	efflux transmembrane transporter activity
AWM58_RS03080	COG1136	(ABC) transporter
AWM58_RS03085	COG2321	neutral zinc metallopeptidase
AWM58_RS03100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM58_RS03130	COG0358	DNA primase activity
AWM58_RS03135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AWM58_RS03140	COG2151	metal-sulfur cluster biosynthetic enzyme
AWM58_RS03185	COG1216	Glycosyl transferase, family 2
AWM58_RS03240	COG1368	sulfuric ester hydrolase activity
AWM58_RS03245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AWM58_RS03265	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AWM58_RS03270	COG0285	dihydrofolate synthase activity
AWM58_RS03310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AWM58_RS03315	COG0583	DNA-binding transcription factor activity
AWM58_RS03325	COG0564	pseudouridine synthase activity
AWM58_RS03355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AWM58_RS03360	COG1136	(ABC) transporter
AWM58_RS03365	COG0577	efflux transmembrane transporter activity
AWM58_RS03370	COG0584	glycerophosphoryl diester phosphodiesterase
AWM58_RS03380	COG1837	Belongs to the UPF0109 family
AWM58_RS03440	COG1349	DNA-binding transcription factor activity
AWM58_RS03445	COG1105	Belongs to the carbohydrate kinase PfkB family
AWM58_RS03450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM58_RS03450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AWM58_RS03450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM58_RS03455	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWM58_RS03455	COG1388	LysM domain
AWM58_RS03460	COG1388	LysM domain
AWM58_RS03460	COG1705	Flagellar rod assembly protein muramidase FlgJ
AWM58_RS03465	COG2801	Transposase and inactivated derivatives
AWM58_RS03480	COG0105	UTP biosynthetic process
AWM58_RS03500	COG0488	(ABC) transporter
AWM58_RS03510	COG0242	peptide deformylase activity
AWM58_RS03515	COG0737	Belongs to the 5'-nucleotidase family
AWM58_RS03520	COG2357	RelA SpoT domain protein
AWM58_RS03525	COG0745	RESPONSE REGULATOR receiver
AWM58_RS03560	COG3425	synthase
AWM58_RS03570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AWM58_RS03625	COG0583	DNA-binding transcription factor activity
AWM58_RS03650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM58_RS03655	COG0765	amino acid transport
AWM58_RS03685	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AWM58_RS03715	COG0539	negative regulation of cytoplasmic translation
AWM58_RS03750	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AWM58_RS03755	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AWM58_RS03765	COG0300	oxidoreductase activity
AWM58_RS03770	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AWM58_RS03770	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AWM58_RS03785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AWM58_RS03790	COG2384	SAM-dependent methyltransferase
AWM58_RS03800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AWM58_RS03805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AWM58_RS03815	COG1088	dTDP-glucose 4,6-dehydratase activity
AWM58_RS03820	COG0582	viral genome integration into host DNA
AWM58_RS03960	COG1051	belongs to the nudix hydrolase family
AWM58_RS03965	COG0628	permease
AWM58_RS03970	COG0457	Tetratricopeptide repeat
AWM58_RS03975	COG1293	RNA-binding protein homologous to eukaryotic snRNP
AWM58_RS03990	COG1129	ABC transporter
AWM58_RS04010	COG0488	(ABC) transporter
AWM58_RS04015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AWM58_RS04020	COG0022	dehydrogenase e1 component
AWM58_RS04020	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM58_RS04025	COG0508	dehydrogenase complex catalyzes the overall conversion of
AWM58_RS04040	COG5492	domain, Protein
AWM58_RS04045	COG0095	Lipoate-protein ligase
AWM58_RS04050	COG3442	glutamine amidotransferase
AWM58_RS04055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWM58_RS04060	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AWM58_RS04090	COG0647	UMP catabolic process
AWM58_RS04105	COG1518	maintenance of DNA repeat elements
AWM58_RS04110	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AWM58_RS04125	COG0105	UTP biosynthetic process
AWM58_RS04160	COG3715	PTS system
AWM58_RS04165	COG3716	PTS system mannose fructose sorbose family IID component
AWM58_RS04170	COG2972	Histidine kinase
AWM58_RS04175	COG4753	response regulator
AWM58_RS04175	COG2207	Transcriptional regulator
AWM58_RS04185	COG1012	belongs to the aldehyde dehydrogenase family
AWM58_RS04280	COG1131	(ABC) transporter
AWM58_RS04295	COG1396	sequence-specific DNA binding
AWM58_RS04355	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AWM58_RS04370	COG1176	ABC-type spermidine putrescine transport system, permease component I
AWM58_RS04375	COG1177	transmembrane transport
AWM58_RS04385	COG4565	transcriptional regulatory protein
AWM58_RS04390	COG3290	protein histidine kinase activity
AWM58_RS04395	COG3493	citrate carrier protein
AWM58_RS04410	COG3700	Belongs to the class B bacterial acid phosphatase family
AWM58_RS04415	COG0038	chloride channel
AWM58_RS04425	COG0628	permease
AWM58_RS04450	COG1104	cysteine desulfurase activity
AWM58_RS04465	COG2357	RelA SpoT domain protein
AWM58_RS04475	COG0564	pseudouridine synthase activity
AWM58_RS04480	COG0280	phosphate acetyltransferase
AWM58_RS04485	COG4221	oxidoreductase activity
AWM58_RS04515	COG2233	PERMEase
AWM58_RS04540	COG2890	protein-(glutamine-N5) methyltransferase activity
AWM58_RS04570	COG1132	(ABC) transporter
AWM58_RS04575	COG1132	(ABC) transporter
AWM58_RS04595	COG3764	Sortase (surface protein transpeptidase)
AWM58_RS04600	COG0346	lactoylglutathione lyase activity
AWM58_RS04615	COG1272	protein, Hemolysin III
AWM58_RS04635	COG0758	DNA mediated transformation
AWM58_RS04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AWM58_RS04685	COG0511	ligase activity, forming carbon-carbon bonds
AWM58_RS04690	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AWM58_RS04705	COG2851	Citrate transporter
AWM58_RS04715	COG0511	ligase activity, forming carbon-carbon bonds
AWM58_RS04720	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AWM58_RS04750	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AWM58_RS04780	COG2188	Transcriptional regulator
AWM58_RS04800	COG0488	(ABC) transporter
AWM58_RS04810	COG0351	phosphomethylpyrimidine kinase
AWM58_RS04810	COG0352	thiamine-phosphate diphosphorylase activity
AWM58_RS04815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AWM58_RS04820	COG1328	CTP reductase activity
AWM58_RS04820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AWM58_RS04825	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AWM58_RS04855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AWM58_RS04865	COG0095	Lipoate-protein ligase
AWM58_RS04875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AWM58_RS04880	COG4684	Psort location CytoplasmicMembrane, score
AWM58_RS04885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWM58_RS04890	COG1079	Belongs to the binding-protein-dependent transport system permease family
AWM58_RS04895	COG4603	Belongs to the binding-protein-dependent transport system permease family
AWM58_RS04900	COG3845	ABC transporter
AWM58_RS04905	COG1744	ABC transporter substrate-binding protein PnrA-like
AWM58_RS04910	COG0295	cytidine deaminase activity
AWM58_RS04915	COG2813	Specifically methylates the guanine in position
AWM58_RS04930	COG5002	protein histidine kinase activity
AWM58_RS04935	COG0745	RESPONSE REGULATOR receiver
AWM58_RS04945	COG0704	Plays a role in the regulation of phosphate uptake
AWM58_RS04960	COG0581	inorganic phosphate transmembrane transporter activity
AWM58_RS04965	COG0573	inorganic phosphate transmembrane transporter activity
AWM58_RS04975	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AWM58_RS04975	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWM58_RS04980	COG0483	inositol monophosphate 1-phosphatase activity
AWM58_RS05075	COG1115	amino acid carrier protein
AWM58_RS05080	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AWM58_RS05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM58_RS05095	COG1126	abc transporter atp-binding protein
AWM58_RS05100	COG0765	amino acid transport
AWM58_RS05105	COG2824	Alkylphosphonate utilization operon protein PhnA
AWM58_RS05120	COG0469	pyruvate kinase activity
AWM58_RS05135	COG1725	Transcriptional regulator
AWM58_RS05140	COG1131	(ABC) transporter
AWM58_RS05165	COG0058	SHG alpha-glucan phosphorylase activity
AWM58_RS05170	COG1640	4-alpha-glucanotransferase
AWM58_RS05175	COG1609	Transcriptional regulator
AWM58_RS05180	COG2182	Extracellular solute-binding protein
AWM58_RS05185	COG1175	transmembrane transport
AWM58_RS05190	COG3833	ABC-type maltose transport systems, permease component
AWM58_RS05205	COG3833	ABC-type maltose transport systems, permease component
AWM58_RS05220	COG0366	Alpha amylase catalytic
AWM58_RS05225	COG2182	Extracellular solute-binding protein
AWM58_RS05235	COG0657	acetylesterase activity
AWM58_RS05240	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AWM58_RS05270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AWM58_RS05275	COG1126	abc transporter atp-binding protein
AWM58_RS05280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM58_RS05290	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWM58_RS05300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AWM58_RS05300	COG3711	transcriptional antiterminator
AWM58_RS05340	COG0157	Belongs to the NadC ModD family
AWM58_RS05355	COG2801	Transposase and inactivated derivatives
AWM58_RS05365	COG1187	pseudouridine synthase activity
AWM58_RS05375	COG2814	Major facilitator Superfamily
AWM58_RS05455	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AWM58_RS05455	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AWM58_RS05460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AWM58_RS05465	COG1956	GAF domain-containing protein
AWM58_RS05485	COG0513	Belongs to the DEAD box helicase family
AWM58_RS05500	COG0726	polysaccharide deacetylase
AWM58_RS05520	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AWM58_RS05525	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AWM58_RS05555	COG2801	Transposase and inactivated derivatives
AWM58_RS05560	COG2801	Transposase and inactivated derivatives
AWM58_RS05575	COG1476	TRANSCRIPTIONal
AWM58_RS05590	COG4122	O-methyltransferase activity
AWM58_RS05595	COG2223	nitrite transmembrane transporter activity
AWM58_RS05610	COG1187	pseudouridine synthase activity
AWM58_RS05650	COG0658	competence protein
AWM58_RS05650	COG2333	competence protein COMEC
AWM58_RS05655	COG1596	polysaccharide export
AWM58_RS05655	COG1555	photosystem II stabilization
AWM58_RS05660	COG0204	Acyl-transferase
AWM58_RS05665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AWM58_RS05680	COG0513	Belongs to the DEAD box helicase family
AWM58_RS05695	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AWM58_RS05710	COG0768	penicillin binding
AWM58_RS05715	COG2116	formate transmembrane transporter activity
AWM58_RS05725	COG1827	regulation of RNA biosynthetic process
AWM58_RS05755	COG3177	Filamentation induced by cAMP protein fic
AWM58_RS05920	COG0582	viral genome integration into host DNA
AWM58_RS05935	COG2755	lipolytic protein G-D-S-L family
AWM58_RS05955	COG1438	arginine binding
AWM58_RS05960	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AWM58_RS05985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AWM58_RS05990	COG0415	Belongs to the DNA photolyase family
AWM58_RS06000	COG0765	amino acid transport
AWM58_RS06005	COG4703	Protein of unknown function (DUF1797)
AWM58_RS06010	COG0542	response to heat
AWM58_RS06015	COG0494	nUDIX hydrolase
AWM58_RS06030	COG3599	regulation of cell shape
AWM58_RS06035	COG2302	S4 RNA-binding domain
AWM58_RS06050	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AWM58_RS06085	COG1217	gtp-binding protein TYPA
AWM58_RS06090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AWM58_RS06095	COG1940	carbohydrate kinase activity
AWM58_RS06105	COG0783	Belongs to the Dps family
AWM58_RS06120	COG4470	Protein conserved in bacteria
AWM58_RS06125	COG1609	Transcriptional regulator
AWM58_RS06130	COG3480	Lon protease (S16) C-terminal proteolytic domain
AWM58_RS06140	COG0742	ribosomal rna small subunit methyltransferase
AWM58_RS06150	COG0549	Belongs to the carbamate kinase family
AWM58_RS06155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AWM58_RS06160	COG1288	antiporter activity
AWM58_RS06170	COG0454	-acetyltransferase
AWM58_RS06175	COG2235	arginine
AWM58_RS06200	COG2972	Histidine kinase
AWM58_RS06215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AWM58_RS06220	COG0785	Cytochrome C biogenesis protein
AWM58_RS06225	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AWM58_RS06230	COG1518	maintenance of DNA repeat elements
AWM58_RS06290	COG1605	Chorismate mutase
AWM58_RS06290	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AWM58_RS06310	COG2226	methyltransferase
AWM58_RS06320	COG3250	beta-galactosidase activity
AWM58_RS06325	COG2207	Transcriptional regulator
AWM58_RS06325	COG4753	response regulator
AWM58_RS06330	COG2972	Histidine kinase
AWM58_RS06345	COG0395	ABC-type sugar transport system, permease component
AWM58_RS06350	COG1175	transmembrane transport
AWM58_RS06360	COG2723	6-phospho-beta-galactosidase activity
AWM58_RS06365	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AWM58_RS06475	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AWM58_RS06480	COG1739	Uncharacterized protein family UPF0029
AWM58_RS06490	COG1098	S1 RNA binding domain
AWM58_RS06500	COG2197	response regulator
AWM58_RS06505	COG4585	Histidine kinase
AWM58_RS06525	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AWM58_RS06525	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AWM58_RS06535	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AWM58_RS06555	COG0583	DNA-binding transcription factor activity
AWM58_RS06560	COG0183	Belongs to the thiolase family
AWM58_RS06565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AWM58_RS06575	COG1028	Short-chain dehydrogenase reductase Sdr
AWM58_RS06580	COG2610	gluconate transmembrane transporter activity
AWM58_RS06595	COG0116	Belongs to the methyltransferase superfamily
AWM58_RS06625	COG3579	cysteine-type endopeptidase activity
AWM58_RS06635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AWM58_RS06640	COG1113	amino acid transport
AWM58_RS06645	COG0492	ferredoxin-NADP+ reductase activity
AWM58_RS06655	COG1126	abc transporter atp-binding protein
AWM58_RS06665	COG0513	Belongs to the DEAD box helicase family
AWM58_RS06675	COG0768	penicillin binding
AWM58_RS06715	COG1131	(ABC) transporter
AWM58_RS06740	COG0446	pyridine nucleotide-disulphide oxidoreductase
AWM58_RS06745	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWM58_RS06780	COG1755	Isoprenylcysteine carboxyl methyltransferase
AWM58_RS06785	COG0656	L-ascorbic acid biosynthetic process
AWM58_RS06795	COG1283	sodium-dependent phosphate transmembrane transporter activity
AWM58_RS06815	COG0561	phosphatase activity
AWM58_RS06820	COG2860	membrane
AWM58_RS06830	COG1105	Belongs to the carbohydrate kinase PfkB family
AWM58_RS06870	COG2217	Heavy metal translocating P-type atpase
AWM58_RS06900	COG2740	Nucleic-acid-binding protein implicated in transcription termination
AWM58_RS06905	COG0195	Participates in both transcription termination and antitermination
AWM58_RS06930	COG4473	ABC transporter
AWM58_RS06935	COG1131	(ABC) transporter
AWM58_RS06940	COG0537	adenosine 5'-monophosphoramidase activity
AWM58_RS06950	COG1316	TRANSCRIPTIONal
AWM58_RS06960	COG0802	atpase or kinase
AWM58_RS06965	COG2252	PERMEase
AWM58_RS06970	COG0561	phosphatase activity
AWM58_RS06980	COG3715	PTS system
AWM58_RS06985	COG3716	PTS system mannose fructose sorbose family IID component
AWM58_RS07010	COG0439	Biotin carboxylase
AWM58_RS07025	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AWM58_RS07030	COG1028	Short-chain dehydrogenase reductase Sdr
AWM58_RS07035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AWM58_RS07060	COG1024	Enoyl-CoA hydratase
AWM58_RS07065	COG0484	heat shock protein binding
AWM58_RS07095	COG0588	phosphoglycerate mutase activity
AWM58_RS07100	COG2261	transglycosylase associated protein
AWM58_RS07125	COG1335	isochorismatase
AWM58_RS07135	COG0436	Aminotransferase
AWM58_RS07145	COG0561	phosphatase activity
AWM58_RS07150	COG0252	asparaginase activity
AWM58_RS07165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AWM58_RS07170	COG1129	ABC transporter
AWM58_RS07185	COG1132	(ABC) transporter
AWM58_RS07190	COG4988	ABC transporter
AWM58_RS07195	COG1120	ATPase activity
AWM58_RS07220	COG3942	CHAP domain
AWM58_RS07220	COG1388	LysM domain
AWM58_RS07250	COG1482	cell wall glycoprotein biosynthetic process
AWM58_RS07255	COG1940	carbohydrate kinase activity
AWM58_RS07265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM58_RS07265	COG1263	PTS System
AWM58_RS07265	COG2190	(PTS) system
AWM58_RS07275	COG1609	Transcriptional regulator
AWM58_RS07295	COG2131	deaminase
AWM58_RS07300	COG0006	proline dipeptidase activity
AWM58_RS07340	COG1194	a g-specific adenine glycosylase
AWM58_RS07345	COG3620	sequence-specific DNA binding
AWM58_RS07350	COG3118	belongs to the thioredoxin family
AWM58_RS07380	COG0681	Belongs to the peptidase S26 family
AWM58_RS07400	COG1882	Formate acetyltransferase
AWM58_RS07405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AWM58_RS07420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AWM58_RS07425	COG2814	Major facilitator Superfamily
AWM58_RS07430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AWM58_RS07455	COG0789	Transcriptional regulator
AWM58_RS07470	COG2081	HI0933 family
AWM58_RS07480	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AWM58_RS07485	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AWM58_RS07505	COG0456	acetyltransferase
AWM58_RS07510	COG1214	PFAM Peptidase M22, glycoprotease
AWM58_RS07525	COG0174	glutamine synthetase
AWM58_RS07530	COG0789	Transcriptional regulator
AWM58_RS07545	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
AWM58_RS07600	COG0668	transmembrane transport
AWM58_RS07610	COG4720	Psort location CytoplasmicMembrane, score
AWM58_RS07615	COG0351	phosphomethylpyrimidine kinase
AWM58_RS07660	COG1929	Belongs to the glycerate kinase type-1 family
AWM58_RS07665	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AWM58_RS07690	COG0577	efflux transmembrane transporter activity
AWM58_RS07695	COG1136	(ABC) transporter
AWM58_RS07700	COG2274	protein secretion by the type I secretion system
AWM58_RS07720	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM58_RS07720	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM58_RS07725	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWM58_RS07770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AWM58_RS07775	COG1476	TRANSCRIPTIONal
AWM58_RS07795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AWM58_RS07805	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AWM58_RS07825	COG1045	serine acetyltransferase
AWM58_RS07840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AWM58_RS07855	COG3711	transcriptional antiterminator
AWM58_RS07875	COG0431	NADPH-dependent FMN reductase
AWM58_RS07880	COG1846	Transcriptional regulator
AWM58_RS07900	COG4589	Belongs to the CDS family
AWM58_RS07910	COG1862	Preprotein translocase
AWM58_RS07920	COG1523	belongs to the glycosyl hydrolase 13 family
AWM58_RS07930	COG3842	ATPase activity
AWM58_RS07970	COG1263	PTS System
AWM58_RS07970	COG2190	(PTS) system
AWM58_RS07970	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AWM58_RS07975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AWM58_RS07995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AWM58_RS08000	COG0512	Glutamine amidotransferase of anthranilate synthase
AWM58_RS08005	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AWM58_RS08045	COG0601	transmembrane transport
AWM58_RS08055	COG1122	ATPase activity
AWM58_RS08075	COG0803	Belongs to the bacterial solute-binding protein 9 family
AWM58_RS08115	COG2205	protein histidine kinase activity
AWM58_RS08120	COG0745	RESPONSE REGULATOR receiver
AWM58_RS08125	COG0577	efflux transmembrane transporter activity
AWM58_RS08130	COG1136	(ABC) transporter
AWM58_RS08190	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AWM58_RS08205	COG1882	Formate acetyltransferase
AWM58_RS08210	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM58_RS08215	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AWM58_RS08220	COG1447	Phosphotransferase system cellobiose-specific component IIA
AWM58_RS08225	COG2390	Transcriptional regulator
AWM58_RS08230	COG1349	DNA-binding transcription factor activity
AWM58_RS08250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AWM58_RS08265	COG0564	pseudouridine synthase activity
AWM58_RS08295	COG0542	response to heat
AWM58_RS08300	COG4463	regulation of RNA biosynthetic process
AWM58_RS08315	COG0450	alkyl hydroperoxide reductase
AWM58_RS08330	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AWM58_RS08340	COG3404	Formiminotransferase-cyclodeaminase
AWM58_RS08355	COG0531	amino acid
AWM58_RS08385	COG3590	peptidase
AWM58_RS08390	COG0366	Alpha amylase catalytic
AWM58_RS08400	COG2188	Transcriptional regulator
AWM58_RS08405	COG1733	regulation of RNA biosynthetic process
AWM58_RS08410	COG2514	catechol 2,3-dioxygenase activity
AWM58_RS08420	COG0602	queuosine metabolic process
AWM58_RS08435	COG1328	CTP reductase activity
AWM58_RS08460	COG1393	Belongs to the ArsC family
AWM58_RS08475	COG0519	Catalyzes the synthesis of GMP from XMP
AWM58_RS08495	COG0582	viral genome integration into host DNA
AWM58_RS08505	COG1396	sequence-specific DNA binding
AWM58_RS08510	COG3617	BRO family, N-terminal domain
AWM58_RS08570	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM58_RS08575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM58_RS08580	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM58_RS08685	COG0305	Participates in initiation and elongation during chromosome replication
AWM58_RS08715	COG1760	l-serine dehydratase
AWM58_RS08720	COG1760	l-serine dehydratase
AWM58_RS08725	COG0741	lytic transglycosylase activity
AWM58_RS08730	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AWM58_RS08745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AWM58_RS08755	COG0612	Peptidase, M16
AWM58_RS08780	COG0516	GMP reductase activity
AWM58_RS08780	COG0517	IMP dehydrogenase activity
AWM58_RS08790	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AWM58_RS08795	COG0488	(ABC) transporter
AWM58_RS08830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AWM58_RS08835	COG1475	DNA binding