locus-tag	class	description
MGAS2096_RS00010	COG0592	DNA-directed DNA polymerase activity
MGAS2096_RS00020	COG0012	GTP binding
MGAS2096_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MGAS2096_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MGAS2096_RS00065	COG0531	amino acid
MGAS2096_RS00240	COG3942	CHAP domain
MGAS2096_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MGAS2096_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MGAS2096_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MGAS2096_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MGAS2096_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MGAS2096_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MGAS2096_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
MGAS2096_RS00350	COG1454	alcohol dehydrogenase
MGAS2096_RS00360	COG0534	Mate efflux family protein
MGAS2096_RS00475	COG0201	protein transport
MGAS2096_RS00610	COG1121	(ABC) transporter
MGAS2096_RS00615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MGAS2096_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MGAS2096_RS00650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MGAS2096_RS00655	COG1459	type II secretion system
MGAS2096_RS00660	COG4537	Required for transformation and DNA binding
MGAS2096_RS00700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MGAS2096_RS00705	COG1363	Peptidase, m42
MGAS2096_RS00715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MGAS2096_RS00720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MGAS2096_RS00730	COG1428	Deoxynucleoside kinase
MGAS2096_RS00735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MGAS2096_RS00775	COG4509	Sortase family
MGAS2096_RS00800	COG2031	fatty acid transporter
MGAS2096_RS00815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MGAS2096_RS00830	COG0251	oxidation-reduction process
MGAS2096_RS00845	COG1269	ATP hydrolysis coupled proton transport
MGAS2096_RS00850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MGAS2096_RS00860	COG1527	subunit (C
MGAS2096_RS00865	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
MGAS2096_RS00900	COG1744	ABC transporter substrate-binding protein PnrA-like
MGAS2096_RS00975	COG3623	hexulose-6-phosphate isomerase
MGAS2096_RS01025	COG3969	phosphoadenosine phosphosulfate
MGAS2096_RS01030	COG1475	DNA binding
MGAS2096_RS01040	COG2801	Transposase and inactivated derivatives
MGAS2096_RS01045	COG2801	Transposase and inactivated derivatives
MGAS2096_RS01060	COG0157	Belongs to the NadC ModD family
MGAS2096_RS01065	COG2801	Transposase and inactivated derivatives
MGAS2096_RS01085	COG1268	BioY protein
MGAS2096_RS01090	COG5433	transposase activity
MGAS2096_RS01100	COG1234	tRNA 3'-trailer cleavage
MGAS2096_RS01140	COG0705	Rhomboid family
MGAS2096_RS01140	COG0457	Tetratricopeptide repeat
MGAS2096_RS01160	COG1132	(ABC) transporter
MGAS2096_RS01165	COG1132	(ABC) transporter
MGAS2096_RS01200	COG3290	protein histidine kinase activity
MGAS2096_RS01245	COG1175	transmembrane transport
MGAS2096_RS01250	COG0395	ABC-type sugar transport system, permease component
MGAS2096_RS01260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MGAS2096_RS01275	COG0084	hydrolase, TatD family'
MGAS2096_RS01300	COG1564	THIamine pyrophosphokinase
MGAS2096_RS01315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MGAS2096_RS01370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MGAS2096_RS01380	COG0719	Fe-S assembly protein
MGAS2096_RS01385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MGAS2096_RS01410	COG4166	transmembrane transport
MGAS2096_RS01415	COG0601	transmembrane transport
MGAS2096_RS01420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MGAS2096_RS01425	COG0444	Belongs to the ABC transporter superfamily
MGAS2096_RS01475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MGAS2096_RS01480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MGAS2096_RS01485	COG1534	Rna-binding protein
MGAS2096_RS01495	COG1713	HD superfamily hydrolase involved in NAD metabolism
MGAS2096_RS01500	COG0799	negative regulation of ribosome biogenesis
MGAS2096_RS01505	COG2226	methyltransferase
MGAS2096_RS01525	COG1464	Belongs to the NlpA lipoprotein family
MGAS2096_RS01550	COG0569	domain protein
MGAS2096_RS01555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MGAS2096_RS01565	COG1704	LemA family
MGAS2096_RS01580	COG0745	RESPONSE REGULATOR receiver
MGAS2096_RS01600	COG1484	DNA-dependent DNA replication
MGAS2096_RS01610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MGAS2096_RS01630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MGAS2096_RS01645	COG1254	Belongs to the acylphosphatase family
MGAS2096_RS01650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGAS2096_RS01705	COG1187	pseudouridine synthase activity
MGAS2096_RS01720	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MGAS2096_RS01725	COG0671	phosphoesterase, PA-phosphatase related
MGAS2096_RS01730	COG1242	4 iron, 4 sulfur cluster binding
MGAS2096_RS01735	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MGAS2096_RS01740	COG1253	flavin adenine dinucleotide binding
MGAS2096_RS01745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGAS2096_RS01760	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MGAS2096_RS01765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MGAS2096_RS01770	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MGAS2096_RS01775	COG1120	ATPase activity
MGAS2096_RS01785	COG2244	polysaccharide biosynthetic process
MGAS2096_RS01800	COG5433	transposase activity
MGAS2096_RS01815	COG0470	DNA polymerase III
MGAS2096_RS01845	COG1393	Belongs to the ArsC family
MGAS2096_RS01850	COG0708	Exodeoxyribonuclease III
MGAS2096_RS01855	COG1304	FMN binding
MGAS2096_RS01935	COG1028	Short-chain dehydrogenase reductase Sdr
MGAS2096_RS01940	COG0673	inositol 2-dehydrogenase activity
MGAS2096_RS01955	COG0494	nUDIX hydrolase
MGAS2096_RS01965	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MGAS2096_RS02025	COG2996	Protein conserved in bacteria
MGAS2096_RS02055	COG1573	uracil-dna glycosylase
MGAS2096_RS02065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MGAS2096_RS02080	COG3328	transposase activity
MGAS2096_RS02145	COG0433	COG0433 Predicted ATPase
MGAS2096_RS02150	COG2814	Major facilitator Superfamily
MGAS2096_RS02160	COG0557	exoribonuclease II activity
MGAS2096_RS02190	COG0463	Glycosyl transferase, family 2
MGAS2096_RS02200	COG0778	Nitroreductase
MGAS2096_RS02205	COG0006	proline dipeptidase activity
MGAS2096_RS02220	COG0438	transferase activity, transferring glycosyl groups
MGAS2096_RS02230	COG4555	ABC transporter
MGAS2096_RS02250	COG0183	Belongs to the thiolase family
MGAS2096_RS02265	COG0745	RESPONSE REGULATOR receiver
MGAS2096_RS02270	COG5002	protein histidine kinase activity
MGAS2096_RS02275	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MGAS2096_RS02285	COG1196	nuclear chromosome segregation
MGAS2096_RS02295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MGAS2096_RS02390	COG0561	phosphatase activity
MGAS2096_RS02395	COG0561	phosphatase activity
MGAS2096_RS02400	COG0552	protein localization to endoplasmic reticulum
MGAS2096_RS02405	COG0477	Major facilitator Superfamily
MGAS2096_RS02410	COG3711	transcriptional antiterminator
MGAS2096_RS02415	COG1263	PTS System
MGAS2096_RS02415	COG2190	(PTS) system
MGAS2096_RS02415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MGAS2096_RS02425	COG3689	TIGRFAM TIGR03943 family protein
MGAS2096_RS02430	COG0701	Predicted permease
MGAS2096_RS02440	COG2183	response to ionizing radiation
MGAS2096_RS02485	COG0826	peptidase U32
MGAS2096_RS02490	COG4443	Transcriptional Coactivator p15 (PC4)
MGAS2096_RS02510	COG0588	phosphoglycerate mutase activity
MGAS2096_RS02540	COG0386	Belongs to the glutathione peroxidase family
MGAS2096_RS02545	COG1164	Oligoendopeptidase f
MGAS2096_RS02555	COG0772	Belongs to the SEDS family
MGAS2096_RS02590	COG1078	dGTPase activity
MGAS2096_RS02605	COG1609	Transcriptional regulator
MGAS2096_RS02615	COG3716	PTS system mannose fructose sorbose family IID component
MGAS2096_RS02620	COG3715	PTS system
MGAS2096_RS02625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MGAS2096_RS02640	COG1028	Short-chain dehydrogenase reductase Sdr
MGAS2096_RS02655	COG0800	Aldolase
MGAS2096_RS02660	COG0546	phosphoglycolate phosphatase activity
MGAS2096_RS02665	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MGAS2096_RS02675	COG2884	Cell division ATP-binding protein ftsE
MGAS2096_RS02680	COG2177	Part of the ABC transporter FtsEX involved in
MGAS2096_RS02695	COG1199	ATP-dependent helicase activity
MGAS2096_RS02695	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MGAS2096_RS02700	COG0436	Aminotransferase
MGAS2096_RS02820	COG1475	DNA binding
MGAS2096_RS02950	COG1705	Flagellar rod assembly protein muramidase FlgJ
MGAS2096_RS02975	COG2188	Transcriptional regulator
MGAS2096_RS02980	COG2222	sugar isomerase
MGAS2096_RS02995	COG0716	FMN binding
MGAS2096_RS03005	COG0038	chloride channel
MGAS2096_RS03090	COG1131	(ABC) transporter
MGAS2096_RS03110	COG4708	membrane
MGAS2096_RS03120	COG1597	lipid kinase activity
MGAS2096_RS03215	COG2321	neutral zinc metallopeptidase
MGAS2096_RS03230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MGAS2096_RS03240	COG1970	mechanosensitive ion channel activity
MGAS2096_RS03245	COG0358	DNA primase activity
MGAS2096_RS03250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MGAS2096_RS03255	COG2151	metal-sulfur cluster biosynthetic enzyme
MGAS2096_RS03300	COG1216	Glycosyl transferase, family 2
MGAS2096_RS03355	COG1368	sulfuric ester hydrolase activity
MGAS2096_RS03360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MGAS2096_RS03380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MGAS2096_RS03385	COG0285	dihydrofolate synthase activity
MGAS2096_RS03395	COG1104	cysteine desulfurase activity
MGAS2096_RS03420	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MGAS2096_RS03425	COG0583	DNA-binding transcription factor activity
MGAS2096_RS03465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MGAS2096_RS03470	COG1136	(ABC) transporter
MGAS2096_RS03475	COG0577	efflux transmembrane transporter activity
MGAS2096_RS03480	COG0584	glycerophosphoryl diester phosphodiesterase
MGAS2096_RS03490	COG1837	Belongs to the UPF0109 family
MGAS2096_RS03540	COG1349	DNA-binding transcription factor activity
MGAS2096_RS03550	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MGAS2096_RS03550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MGAS2096_RS03550	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MGAS2096_RS03555	COG1705	Flagellar rod assembly protein muramidase FlgJ
MGAS2096_RS03555	COG1388	LysM domain
MGAS2096_RS03560	COG1705	Flagellar rod assembly protein muramidase FlgJ
MGAS2096_RS03560	COG1388	LysM domain
MGAS2096_RS03565	COG2801	Transposase and inactivated derivatives
MGAS2096_RS03580	COG0105	UTP biosynthetic process
MGAS2096_RS03600	COG0488	(ABC) transporter
MGAS2096_RS03610	COG0242	peptide deformylase activity
MGAS2096_RS03615	COG0737	Belongs to the 5'-nucleotidase family
MGAS2096_RS03620	COG2357	RelA SpoT domain protein
MGAS2096_RS03625	COG0745	RESPONSE REGULATOR receiver
MGAS2096_RS03665	COG3425	synthase
MGAS2096_RS03675	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MGAS2096_RS03735	COG0583	DNA-binding transcription factor activity
MGAS2096_RS03760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MGAS2096_RS03765	COG0765	amino acid transport
MGAS2096_RS03785	COG0187	DNA topoisomerase II activity
MGAS2096_RS03815	COG0539	negative regulation of cytoplasmic translation
MGAS2096_RS03855	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MGAS2096_RS03860	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MGAS2096_RS03870	COG0300	oxidoreductase activity
MGAS2096_RS03875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MGAS2096_RS03875	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MGAS2096_RS03890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MGAS2096_RS03895	COG2384	SAM-dependent methyltransferase
MGAS2096_RS03905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MGAS2096_RS03910	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MGAS2096_RS03925	COG1088	dTDP-glucose 4,6-dehydratase activity
MGAS2096_RS03930	COG1051	belongs to the nudix hydrolase family
MGAS2096_RS03935	COG0628	permease
MGAS2096_RS03940	COG0457	Tetratricopeptide repeat
MGAS2096_RS03945	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MGAS2096_RS03960	COG1129	ABC transporter
MGAS2096_RS03980	COG0488	(ABC) transporter
MGAS2096_RS03985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MGAS2096_RS03990	COG0508	dehydrogenase complex catalyzes the overall conversion of
MGAS2096_RS03990	COG0022	dehydrogenase e1 component
MGAS2096_RS03995	COG0508	dehydrogenase complex catalyzes the overall conversion of
MGAS2096_RS04015	COG0095	Lipoate-protein ligase
MGAS2096_RS04020	COG3442	glutamine amidotransferase
MGAS2096_RS04025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MGAS2096_RS04030	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MGAS2096_RS04050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MGAS2096_RS04060	COG0647	UMP catabolic process
MGAS2096_RS04075	COG1518	maintenance of DNA repeat elements
MGAS2096_RS04080	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MGAS2096_RS04095	COG0105	UTP biosynthetic process
MGAS2096_RS04100	COG5433	transposase activity
MGAS2096_RS04140	COG3715	PTS system
MGAS2096_RS04145	COG3716	PTS system mannose fructose sorbose family IID component
MGAS2096_RS04150	COG2972	Histidine kinase
MGAS2096_RS04155	COG2207	Transcriptional regulator
MGAS2096_RS04155	COG4753	response regulator
MGAS2096_RS04165	COG1012	belongs to the aldehyde dehydrogenase family
MGAS2096_RS04180	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MGAS2096_RS04260	COG1131	(ABC) transporter
MGAS2096_RS04275	COG1396	sequence-specific DNA binding
MGAS2096_RS04315	COG0285	dihydrofolate synthase activity
MGAS2096_RS04335	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MGAS2096_RS04350	COG1176	ABC-type spermidine putrescine transport system, permease component I
MGAS2096_RS04355	COG1177	transmembrane transport
MGAS2096_RS04365	COG4565	transcriptional regulatory protein
MGAS2096_RS04375	COG3493	citrate carrier protein
MGAS2096_RS04390	COG3700	Belongs to the class B bacterial acid phosphatase family
MGAS2096_RS04395	COG0038	chloride channel
MGAS2096_RS04405	COG0628	permease
MGAS2096_RS04415	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MGAS2096_RS04430	COG1104	cysteine desulfurase activity
MGAS2096_RS04460	COG0280	phosphate acetyltransferase
MGAS2096_RS04465	COG4221	oxidoreductase activity
MGAS2096_RS04480	COG1174	glycine betaine transport
MGAS2096_RS04495	COG2233	PERMEase
MGAS2096_RS04520	COG2890	protein-(glutamine-N5) methyltransferase activity
MGAS2096_RS04550	COG1132	(ABC) transporter
MGAS2096_RS04555	COG1132	(ABC) transporter
MGAS2096_RS04575	COG3764	Sortase (surface protein transpeptidase)
MGAS2096_RS04580	COG0346	lactoylglutathione lyase activity
MGAS2096_RS04595	COG1272	protein, Hemolysin III
MGAS2096_RS04615	COG0758	DNA mediated transformation
MGAS2096_RS04620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MGAS2096_RS04660	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MGAS2096_RS04680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MGAS2096_RS04710	COG0488	(ABC) transporter
MGAS2096_RS04720	COG0351	phosphomethylpyrimidine kinase
MGAS2096_RS04720	COG0352	thiamine-phosphate diphosphorylase activity
MGAS2096_RS04730	COG1328	CTP reductase activity
MGAS2096_RS04730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MGAS2096_RS04735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MGAS2096_RS04765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MGAS2096_RS04775	COG0095	Lipoate-protein ligase
MGAS2096_RS04785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MGAS2096_RS04790	COG4684	Psort location CytoplasmicMembrane, score
MGAS2096_RS04795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MGAS2096_RS04800	COG1079	Belongs to the binding-protein-dependent transport system permease family
MGAS2096_RS04805	COG4603	Belongs to the binding-protein-dependent transport system permease family
MGAS2096_RS04810	COG3845	ABC transporter
MGAS2096_RS04815	COG1744	ABC transporter substrate-binding protein PnrA-like
MGAS2096_RS04820	COG0295	cytidine deaminase activity
MGAS2096_RS04825	COG2813	Specifically methylates the guanine in position
MGAS2096_RS04840	COG5002	protein histidine kinase activity
MGAS2096_RS04845	COG0745	RESPONSE REGULATOR receiver
MGAS2096_RS04855	COG0704	Plays a role in the regulation of phosphate uptake
MGAS2096_RS04870	COG0581	inorganic phosphate transmembrane transporter activity
MGAS2096_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
MGAS2096_RS04885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MGAS2096_RS04885	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MGAS2096_RS04890	COG0483	inositol monophosphate 1-phosphatase activity
MGAS2096_RS04905	COG0196	riboflavin kinase activity
MGAS2096_RS04935	COG1136	(ABC) transporter
MGAS2096_RS04935	COG4591	ABC-type transport system involved in lipoprotein release permease component
MGAS2096_RS04985	COG1115	amino acid carrier protein
MGAS2096_RS05000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MGAS2096_RS05005	COG1126	abc transporter atp-binding protein
MGAS2096_RS05010	COG0765	amino acid transport
MGAS2096_RS05015	COG2824	Alkylphosphonate utilization operon protein PhnA
MGAS2096_RS05030	COG0469	pyruvate kinase activity
MGAS2096_RS05045	COG1725	Transcriptional regulator
MGAS2096_RS05050	COG1131	(ABC) transporter
MGAS2096_RS05070	COG0058	SHG alpha-glucan phosphorylase activity
MGAS2096_RS05080	COG1609	Transcriptional regulator
MGAS2096_RS05085	COG2182	Extracellular solute-binding protein
MGAS2096_RS05090	COG1175	transmembrane transport
MGAS2096_RS05095	COG3833	ABC-type maltose transport systems, permease component
MGAS2096_RS05110	COG0657	acetylesterase activity
MGAS2096_RS05115	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MGAS2096_RS05125	COG1696	Membrane protein involved in D-alanine export
MGAS2096_RS05145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MGAS2096_RS05150	COG1126	abc transporter atp-binding protein
MGAS2096_RS05160	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MGAS2096_RS05170	COG1447	Phosphotransferase system cellobiose-specific component IIA
MGAS2096_RS05180	COG3711	transcriptional antiterminator
MGAS2096_RS05180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MGAS2096_RS05190	COG2723	6-phospho-beta-galactosidase activity
MGAS2096_RS05225	COG1187	pseudouridine synthase activity
MGAS2096_RS05275	COG2205	protein histidine kinase activity
MGAS2096_RS05290	COG1136	(ABC) transporter
MGAS2096_RS05315	COG1309	transcriptional regulator
MGAS2096_RS05340	COG0741	lytic transglycosylase activity
MGAS2096_RS05340	COG0791	NLP P60 protein
MGAS2096_RS05345	COG4509	Sortase family
MGAS2096_RS05460	COG4443	Transcriptional Coactivator p15 (PC4)
MGAS2096_RS05465	COG1475	DNA binding
MGAS2096_RS05555	COG1192	Involved in chromosome partitioning
MGAS2096_RS05595	COG4109	DRTGG domain
MGAS2096_RS05630	COG5433	transposase activity
MGAS2096_RS05640	COG1956	GAF domain-containing protein
MGAS2096_RS05660	COG0513	Belongs to the DEAD box helicase family
MGAS2096_RS05665	COG0726	polysaccharide deacetylase
MGAS2096_RS05690	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MGAS2096_RS05695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGAS2096_RS05700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MGAS2096_RS05715	COG2801	Transposase and inactivated derivatives
MGAS2096_RS05720	COG2801	Transposase and inactivated derivatives
MGAS2096_RS05735	COG1476	TRANSCRIPTIONal
MGAS2096_RS05750	COG4122	O-methyltransferase activity
MGAS2096_RS05755	COG2223	nitrite transmembrane transporter activity
MGAS2096_RS05770	COG1187	pseudouridine synthase activity
MGAS2096_RS05825	COG0204	Acyl-transferase
MGAS2096_RS05830	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MGAS2096_RS05850	COG0513	Belongs to the DEAD box helicase family
MGAS2096_RS05865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MGAS2096_RS05890	COG1827	regulation of RNA biosynthetic process
MGAS2096_RS05920	COG2755	lipolytic protein G-D-S-L family
MGAS2096_RS05935	COG0497	DNA recombination
MGAS2096_RS05940	COG1438	arginine binding
MGAS2096_RS05945	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MGAS2096_RS05970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MGAS2096_RS05975	COG0415	Belongs to the DNA photolyase family
MGAS2096_RS05985	COG0765	amino acid transport
MGAS2096_RS05990	COG4703	Protein of unknown function (DUF1797)
MGAS2096_RS05995	COG0542	response to heat
MGAS2096_RS06000	COG0494	nUDIX hydrolase
MGAS2096_RS06015	COG3599	regulation of cell shape
MGAS2096_RS06020	COG2302	S4 RNA-binding domain
MGAS2096_RS06035	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MGAS2096_RS06070	COG1217	gtp-binding protein TYPA
MGAS2096_RS06080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MGAS2096_RS06085	COG1940	carbohydrate kinase activity
MGAS2096_RS06095	COG0783	Belongs to the Dps family
MGAS2096_RS06110	COG4470	Protein conserved in bacteria
MGAS2096_RS06115	COG1609	Transcriptional regulator
MGAS2096_RS06120	COG3480	Lon protease (S16) C-terminal proteolytic domain
MGAS2096_RS06130	COG0742	ribosomal rna small subunit methyltransferase
MGAS2096_RS06140	COG0549	Belongs to the carbamate kinase family
MGAS2096_RS06145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MGAS2096_RS06150	COG1288	antiporter activity
MGAS2096_RS06165	COG2235	arginine
MGAS2096_RS06190	COG2972	Histidine kinase
MGAS2096_RS06205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MGAS2096_RS06210	COG0785	Cytochrome C biogenesis protein
MGAS2096_RS06215	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MGAS2096_RS06220	COG1518	maintenance of DNA repeat elements
MGAS2096_RS06280	COG1605	Chorismate mutase
MGAS2096_RS06280	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MGAS2096_RS06300	COG2226	methyltransferase
MGAS2096_RS06310	COG3250	beta-galactosidase activity
MGAS2096_RS06315	COG4753	response regulator
MGAS2096_RS06315	COG2207	Transcriptional regulator
MGAS2096_RS06320	COG2972	Histidine kinase
MGAS2096_RS06330	COG1653	transport
MGAS2096_RS06335	COG0395	ABC-type sugar transport system, permease component
MGAS2096_RS06340	COG1175	transmembrane transport
MGAS2096_RS06350	COG2723	6-phospho-beta-galactosidase activity
MGAS2096_RS06370	COG0383	alpha-mannosidase activity
MGAS2096_RS06465	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MGAS2096_RS06470	COG1739	Uncharacterized protein family UPF0029
MGAS2096_RS06480	COG1098	S1 RNA binding domain
MGAS2096_RS06490	COG2197	response regulator
MGAS2096_RS06495	COG4585	Histidine kinase
MGAS2096_RS06505	COG2815	serine threonine protein kinase
MGAS2096_RS06505	COG0515	serine threonine protein kinase
MGAS2096_RS06515	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MGAS2096_RS06515	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MGAS2096_RS06525	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MGAS2096_RS06545	COG0583	DNA-binding transcription factor activity
MGAS2096_RS06550	COG0183	Belongs to the thiolase family
MGAS2096_RS06555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MGAS2096_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
MGAS2096_RS06585	COG0116	Belongs to the methyltransferase superfamily
MGAS2096_RS06605	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MGAS2096_RS06610	COG3579	cysteine-type endopeptidase activity
MGAS2096_RS06620	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MGAS2096_RS06625	COG1113	amino acid transport
MGAS2096_RS06630	COG0492	ferredoxin-NADP+ reductase activity
MGAS2096_RS06640	COG1126	abc transporter atp-binding protein
MGAS2096_RS06650	COG0513	Belongs to the DEAD box helicase family
MGAS2096_RS06660	COG0768	penicillin binding
MGAS2096_RS06695	COG1131	(ABC) transporter
MGAS2096_RS06720	COG0446	pyridine nucleotide-disulphide oxidoreductase
MGAS2096_RS06725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MGAS2096_RS06760	COG1755	Isoprenylcysteine carboxyl methyltransferase
MGAS2096_RS06765	COG0656	L-ascorbic acid biosynthetic process
MGAS2096_RS06775	COG1283	sodium-dependent phosphate transmembrane transporter activity
MGAS2096_RS06795	COG0561	phosphatase activity
MGAS2096_RS06800	COG2860	membrane
MGAS2096_RS06810	COG1105	Belongs to the carbohydrate kinase PfkB family
MGAS2096_RS06850	COG2217	Heavy metal translocating P-type atpase
MGAS2096_RS06880	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MGAS2096_RS06885	COG0195	Participates in both transcription termination and antitermination
MGAS2096_RS06905	COG1705	Flagellar rod assembly protein muramidase FlgJ
MGAS2096_RS07025	COG1783	phage Terminase large subunit
MGAS2096_RS07145	COG4974	Belongs to the 'phage' integrase family
MGAS2096_RS07165	COG4473	ABC transporter
MGAS2096_RS07170	COG1131	(ABC) transporter
MGAS2096_RS07175	COG0537	adenosine 5'-monophosphoramidase activity
MGAS2096_RS07185	COG1316	TRANSCRIPTIONal
MGAS2096_RS07195	COG0802	atpase or kinase
MGAS2096_RS07200	COG2252	PERMEase
MGAS2096_RS07215	COG3715	PTS system
MGAS2096_RS07220	COG3716	PTS system mannose fructose sorbose family IID component
MGAS2096_RS07245	COG0439	Biotin carboxylase
MGAS2096_RS07260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MGAS2096_RS07265	COG1028	Short-chain dehydrogenase reductase Sdr
MGAS2096_RS07270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MGAS2096_RS07295	COG1024	Enoyl-CoA hydratase
MGAS2096_RS07300	COG0484	heat shock protein binding
MGAS2096_RS07330	COG0588	phosphoglycerate mutase activity
MGAS2096_RS07335	COG2261	transglycosylase associated protein
MGAS2096_RS07360	COG0574	Belongs to the PEP-utilizing enzyme family
MGAS2096_RS07360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MGAS2096_RS07365	COG1335	isochorismatase
MGAS2096_RS07375	COG0436	Aminotransferase
MGAS2096_RS07385	COG0561	phosphatase activity
MGAS2096_RS07390	COG0252	asparaginase activity
MGAS2096_RS07405	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MGAS2096_RS07410	COG1129	ABC transporter
MGAS2096_RS07425	COG1132	(ABC) transporter
MGAS2096_RS07430	COG4988	ABC transporter
MGAS2096_RS07435	COG1120	ATPase activity
MGAS2096_RS07460	COG3942	CHAP domain
MGAS2096_RS07460	COG1388	LysM domain
MGAS2096_RS07485	COG5433	transposase activity
MGAS2096_RS07490	COG1482	cell wall glycoprotein biosynthetic process
MGAS2096_RS07495	COG1940	carbohydrate kinase activity
MGAS2096_RS07515	COG1609	Transcriptional regulator
MGAS2096_RS07535	COG2131	deaminase
MGAS2096_RS07540	COG0006	proline dipeptidase activity
MGAS2096_RS07580	COG1194	a g-specific adenine glycosylase
MGAS2096_RS07590	COG3118	belongs to the thioredoxin family
MGAS2096_RS07620	COG0681	Belongs to the peptidase S26 family
MGAS2096_RS07625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MGAS2096_RS07640	COG1882	Formate acetyltransferase
MGAS2096_RS07645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MGAS2096_RS07660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MGAS2096_RS07665	COG2814	Major facilitator Superfamily
MGAS2096_RS07670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MGAS2096_RS07710	COG2081	HI0933 family
MGAS2096_RS07720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MGAS2096_RS07725	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MGAS2096_RS07745	COG0456	acetyltransferase
MGAS2096_RS07750	COG1214	PFAM Peptidase M22, glycoprotease
MGAS2096_RS07765	COG0174	glutamine synthetase
MGAS2096_RS07770	COG0789	Transcriptional regulator
MGAS2096_RS07785	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MGAS2096_RS07840	COG0668	transmembrane transport
MGAS2096_RS07850	COG4720	Psort location CytoplasmicMembrane, score
MGAS2096_RS07855	COG0351	phosphomethylpyrimidine kinase
MGAS2096_RS07900	COG1929	Belongs to the glycerate kinase type-1 family
MGAS2096_RS07905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MGAS2096_RS07935	COG0577	efflux transmembrane transporter activity
MGAS2096_RS07940	COG1136	(ABC) transporter
MGAS2096_RS07945	COG1132	(ABC) transporter
MGAS2096_RS07965	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MGAS2096_RS07965	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MGAS2096_RS07970	COG1447	Phosphotransferase system cellobiose-specific component IIA
MGAS2096_RS08020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MGAS2096_RS08025	COG1476	TRANSCRIPTIONal
MGAS2096_RS08045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MGAS2096_RS08055	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MGAS2096_RS08070	COG1045	serine acetyltransferase
MGAS2096_RS08085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MGAS2096_RS08100	COG3711	transcriptional antiterminator
MGAS2096_RS08130	COG1846	Transcriptional regulator
MGAS2096_RS08150	COG4589	Belongs to the CDS family
MGAS2096_RS08160	COG1862	Preprotein translocase
MGAS2096_RS08170	COG1523	belongs to the glycosyl hydrolase 13 family
MGAS2096_RS08180	COG3842	ATPase activity
MGAS2096_RS08225	COG2190	(PTS) system
MGAS2096_RS08225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MGAS2096_RS08225	COG1263	PTS System
MGAS2096_RS08230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MGAS2096_RS08265	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MGAS2096_RS08270	COG0512	Glutamine amidotransferase of anthranilate synthase
MGAS2096_RS08275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MGAS2096_RS08310	COG0601	transmembrane transport
MGAS2096_RS08340	COG0803	Belongs to the bacterial solute-binding protein 9 family
MGAS2096_RS08350	COG5433	transposase activity
MGAS2096_RS08355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MGAS2096_RS08355	COG1404	Belongs to the peptidase S8 family
MGAS2096_RS08375	COG1196	nuclear chromosome segregation
MGAS2096_RS08380	COG3711	transcriptional antiterminator
MGAS2096_RS08390	COG1705	Flagellar rod assembly protein muramidase FlgJ
MGAS2096_RS08390	COG3942	CHAP domain
MGAS2096_RS08395	COG2205	protein histidine kinase activity
MGAS2096_RS08400	COG0745	RESPONSE REGULATOR receiver
MGAS2096_RS08405	COG0577	efflux transmembrane transporter activity
MGAS2096_RS08410	COG1136	(ABC) transporter
MGAS2096_RS08475	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MGAS2096_RS08490	COG1882	Formate acetyltransferase
MGAS2096_RS08495	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MGAS2096_RS08500	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MGAS2096_RS08505	COG1447	Phosphotransferase system cellobiose-specific component IIA
MGAS2096_RS08510	COG2390	Transcriptional regulator
MGAS2096_RS08515	COG1349	DNA-binding transcription factor activity
MGAS2096_RS08520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MGAS2096_RS08550	COG0564	pseudouridine synthase activity
MGAS2096_RS08585	COG4463	regulation of RNA biosynthetic process
MGAS2096_RS08600	COG0450	alkyl hydroperoxide reductase
MGAS2096_RS08615	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MGAS2096_RS08625	COG3404	Formiminotransferase-cyclodeaminase
MGAS2096_RS08640	COG0531	amino acid
MGAS2096_RS08670	COG3590	peptidase
MGAS2096_RS08675	COG0366	Alpha amylase catalytic
MGAS2096_RS08680	COG1263	PTS System
MGAS2096_RS08680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MGAS2096_RS08685	COG2188	Transcriptional regulator
MGAS2096_RS08690	COG1733	regulation of RNA biosynthetic process
MGAS2096_RS08695	COG2514	catechol 2,3-dioxygenase activity
MGAS2096_RS08705	COG0602	queuosine metabolic process
MGAS2096_RS08715	COG0673	inositol 2-dehydrogenase activity
MGAS2096_RS08720	COG1328	CTP reductase activity
MGAS2096_RS08745	COG1393	Belongs to the ArsC family
MGAS2096_RS08760	COG0519	Catalyzes the synthesis of GMP from XMP
MGAS2096_RS08770	COG2814	Major facilitator Superfamily
MGAS2096_RS08800	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MGAS2096_RS08805	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MGAS2096_RS08810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MGAS2096_RS08830	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MGAS2096_RS08890	COG1511	domain protein
MGAS2096_RS08910	COG0305	Participates in initiation and elongation during chromosome replication
MGAS2096_RS08940	COG1760	l-serine dehydratase
MGAS2096_RS08945	COG1760	l-serine dehydratase
MGAS2096_RS08950	COG0741	lytic transglycosylase activity
MGAS2096_RS08955	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MGAS2096_RS08970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MGAS2096_RS08980	COG0612	Peptidase, M16
MGAS2096_RS09000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MGAS2096_RS09020	COG0517	IMP dehydrogenase activity
MGAS2096_RS09020	COG0516	GMP reductase activity
MGAS2096_RS09030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MGAS2096_RS09035	COG0488	(ABC) transporter
MGAS2096_RS09070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MGAS2096_RS09075	COG1475	DNA binding