locus-tag	class	description
M5005_RS00010	COG0592	DNA-directed DNA polymerase activity
M5005_RS00020	COG0012	GTP binding
M5005_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M5005_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M5005_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M5005_RS00065	COG0531	amino acid
M5005_RS00240	COG3942	CHAP domain
M5005_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M5005_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M5005_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M5005_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M5005_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M5005_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M5005_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
M5005_RS00350	COG1454	alcohol dehydrogenase
M5005_RS00355	COG1064	alcohol dehydrogenase
M5005_RS00360	COG0534	Mate efflux family protein
M5005_RS00470	COG0201	protein transport
M5005_RS00605	COG1121	(ABC) transporter
M5005_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M5005_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M5005_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M5005_RS00650	COG1459	type II secretion system
M5005_RS00655	COG4537	Required for transformation and DNA binding
M5005_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
M5005_RS00700	COG1363	Peptidase, m42
M5005_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M5005_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M5005_RS00725	COG1428	Deoxynucleoside kinase
M5005_RS00730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M5005_RS00760	COG4509	Sortase family
M5005_RS00770	COG4372	Transposase
M5005_RS00795	COG2031	fatty acid transporter
M5005_RS00815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M5005_RS00830	COG0251	oxidation-reduction process
M5005_RS00845	COG1269	ATP hydrolysis coupled proton transport
M5005_RS00850	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M5005_RS00860	COG1527	subunit (C
M5005_RS00865	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
M5005_RS00900	COG1744	ABC transporter substrate-binding protein PnrA-like
M5005_RS00940	COG0626	cystathionine gamma-synthase activity
M5005_RS00970	COG3623	hexulose-6-phosphate isomerase
M5005_RS00990	COG3448	diguanylate cyclase activity
M5005_RS00990	COG4175	Glycine betaine
M5005_RS01000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M5005_RS01000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
M5005_RS01020	COG3969	phosphoadenosine phosphosulfate
M5005_RS01025	COG1475	DNA binding
M5005_RS01035	COG2801	Transposase and inactivated derivatives
M5005_RS01040	COG2801	Transposase and inactivated derivatives
M5005_RS01055	COG0157	Belongs to the NadC ModD family
M5005_RS01060	COG2801	Transposase and inactivated derivatives
M5005_RS01080	COG1268	BioY protein
M5005_RS01085	COG1234	tRNA 3'-trailer cleavage
M5005_RS01115	COG5433	transposase activity
M5005_RS01130	COG0705	Rhomboid family
M5005_RS01130	COG0457	Tetratricopeptide repeat
M5005_RS01150	COG1132	(ABC) transporter
M5005_RS01155	COG1132	(ABC) transporter
M5005_RS01165	COG0756	dUTP diphosphatase activity
M5005_RS01190	COG3290	protein histidine kinase activity
M5005_RS01215	COG1847	R3H domain protein
M5005_RS01235	COG1175	transmembrane transport
M5005_RS01240	COG0395	ABC-type sugar transport system, permease component
M5005_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M5005_RS01265	COG0084	hydrolase, TatD family'
M5005_RS01290	COG1564	THIamine pyrophosphokinase
M5005_RS01305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M5005_RS01340	COG0765	amino acid transport
M5005_RS01360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M5005_RS01370	COG0719	Fe-S assembly protein
M5005_RS01375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M5005_RS01390	COG1686	Belongs to the peptidase S11 family
M5005_RS01395	COG1686	Belongs to the peptidase S11 family
M5005_RS01400	COG4166	transmembrane transport
M5005_RS01405	COG0601	transmembrane transport
M5005_RS01410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M5005_RS01415	COG0444	Belongs to the ABC transporter superfamily
M5005_RS01460	COG5433	transposase activity
M5005_RS01475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
M5005_RS01480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M5005_RS01485	COG1534	Rna-binding protein
M5005_RS01495	COG1713	HD superfamily hydrolase involved in NAD metabolism
M5005_RS01500	COG0799	negative regulation of ribosome biogenesis
M5005_RS01505	COG2226	methyltransferase
M5005_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M5005_RS01525	COG1464	Belongs to the NlpA lipoprotein family
M5005_RS01540	COG1114	Component of the transport system for branched-chain amino acids
M5005_RS01550	COG0569	domain protein
M5005_RS01555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M5005_RS01565	COG1704	LemA family
M5005_RS01580	COG0745	RESPONSE REGULATOR receiver
M5005_RS01600	COG1484	DNA-dependent DNA replication
M5005_RS01610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
M5005_RS01630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M5005_RS01645	COG1254	Belongs to the acylphosphatase family
M5005_RS01660	COG5433	transposase activity
M5005_RS01665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M5005_RS01720	COG1187	pseudouridine synthase activity
M5005_RS01735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
M5005_RS01740	COG0671	phosphoesterase, PA-phosphatase related
M5005_RS01745	COG1242	4 iron, 4 sulfur cluster binding
M5005_RS01750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
M5005_RS01755	COG1253	flavin adenine dinucleotide binding
M5005_RS01760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M5005_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5005_RS01780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M5005_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M5005_RS01790	COG1120	ATPase activity
M5005_RS01800	COG2244	polysaccharide biosynthetic process
M5005_RS01825	COG0470	DNA polymerase III
M5005_RS01860	COG1393	Belongs to the ArsC family
M5005_RS01865	COG0708	Exodeoxyribonuclease III
M5005_RS01875	COG1304	FMN binding
M5005_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
M5005_RS01960	COG0673	inositol 2-dehydrogenase activity
M5005_RS01975	COG0494	nUDIX hydrolase
M5005_RS01985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M5005_RS02040	COG5433	transposase activity
M5005_RS02085	COG1702	phosphate starvation-inducible protein PhoH
M5005_RS02090	COG1573	uracil-dna glycosylase
M5005_RS02100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M5005_RS02180	COG0433	COG0433 Predicted ATPase
M5005_RS02185	COG2814	Major facilitator Superfamily
M5005_RS02195	COG0557	exoribonuclease II activity
M5005_RS02225	COG0463	Glycosyl transferase, family 2
M5005_RS02235	COG0778	Nitroreductase
M5005_RS02240	COG0006	proline dipeptidase activity
M5005_RS02245	COG1609	Transcriptional regulator
M5005_RS02255	COG0438	transferase activity, transferring glycosyl groups
M5005_RS02265	COG4555	ABC transporter
M5005_RS02285	COG0183	Belongs to the thiolase family
M5005_RS02300	COG0745	RESPONSE REGULATOR receiver
M5005_RS02305	COG5002	protein histidine kinase activity
M5005_RS02310	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
M5005_RS02320	COG1196	nuclear chromosome segregation
M5005_RS02330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M5005_RS02410	COG4695	Portal protein
M5005_RS02460	COG0561	phosphatase activity
M5005_RS02465	COG0561	phosphatase activity
M5005_RS02470	COG0552	protein localization to endoplasmic reticulum
M5005_RS02475	COG0477	Major facilitator Superfamily
M5005_RS02480	COG3711	transcriptional antiterminator
M5005_RS02485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5005_RS02485	COG1263	PTS System
M5005_RS02485	COG2190	(PTS) system
M5005_RS02495	COG3689	TIGRFAM TIGR03943 family protein
M5005_RS02500	COG0701	Predicted permease
M5005_RS02510	COG2183	response to ionizing radiation
M5005_RS02555	COG0826	peptidase U32
M5005_RS02560	COG4443	Transcriptional Coactivator p15 (PC4)
M5005_RS02610	COG0386	Belongs to the glutathione peroxidase family
M5005_RS02615	COG1164	Oligoendopeptidase f
M5005_RS02625	COG0772	Belongs to the SEDS family
M5005_RS02660	COG1078	dGTPase activity
M5005_RS02675	COG1609	Transcriptional regulator
M5005_RS02685	COG3716	PTS system mannose fructose sorbose family IID component
M5005_RS02690	COG3715	PTS system
M5005_RS02695	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5005_RS02710	COG1028	Short-chain dehydrogenase reductase Sdr
M5005_RS02725	COG0800	Aldolase
M5005_RS02730	COG0546	phosphoglycolate phosphatase activity
M5005_RS02735	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M5005_RS02745	COG2884	Cell division ATP-binding protein ftsE
M5005_RS02750	COG2177	Part of the ABC transporter FtsEX involved in
M5005_RS02765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M5005_RS02765	COG1199	ATP-dependent helicase activity
M5005_RS02770	COG0436	Aminotransferase
M5005_RS02805	COG2188	Transcriptional regulator
M5005_RS02810	COG2222	sugar isomerase
M5005_RS02820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M5005_RS02825	COG0716	FMN binding
M5005_RS02835	COG0038	chloride channel
M5005_RS02925	COG1131	(ABC) transporter
M5005_RS02945	COG4708	membrane
M5005_RS02955	COG1597	lipid kinase activity
M5005_RS03040	COG0577	efflux transmembrane transporter activity
M5005_RS03050	COG2321	neutral zinc metallopeptidase
M5005_RS03065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M5005_RS03075	COG1970	mechanosensitive ion channel activity
M5005_RS03080	COG0358	DNA primase activity
M5005_RS03085	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M5005_RS03090	COG2151	metal-sulfur cluster biosynthetic enzyme
M5005_RS03135	COG1216	Glycosyl transferase, family 2
M5005_RS03190	COG1368	sulfuric ester hydrolase activity
M5005_RS03195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M5005_RS03215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M5005_RS03220	COG0285	dihydrofolate synthase activity
M5005_RS03230	COG1104	cysteine desulfurase activity
M5005_RS03255	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M5005_RS03260	COG0583	DNA-binding transcription factor activity
M5005_RS03270	COG0564	pseudouridine synthase activity
M5005_RS03300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M5005_RS03305	COG1136	(ABC) transporter
M5005_RS03310	COG0577	efflux transmembrane transporter activity
M5005_RS03315	COG0584	glycerophosphoryl diester phosphodiesterase
M5005_RS03325	COG1837	Belongs to the UPF0109 family
M5005_RS03375	COG1349	DNA-binding transcription factor activity
M5005_RS03380	COG1105	Belongs to the carbohydrate kinase PfkB family
M5005_RS03385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M5005_RS03385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M5005_RS03385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M5005_RS03390	COG1388	LysM domain
M5005_RS03390	COG1705	Flagellar rod assembly protein muramidase FlgJ
M5005_RS03395	COG1705	Flagellar rod assembly protein muramidase FlgJ
M5005_RS03395	COG1388	LysM domain
M5005_RS03400	COG2801	Transposase and inactivated derivatives
M5005_RS03415	COG0105	UTP biosynthetic process
M5005_RS03435	COG0488	(ABC) transporter
M5005_RS03445	COG0242	peptide deformylase activity
M5005_RS03450	COG0737	Belongs to the 5'-nucleotidase family
M5005_RS03455	COG2357	RelA SpoT domain protein
M5005_RS03460	COG0745	RESPONSE REGULATOR receiver
M5005_RS03495	COG3425	synthase
M5005_RS03505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M5005_RS03565	COG0583	DNA-binding transcription factor activity
M5005_RS03590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M5005_RS03595	COG0765	amino acid transport
M5005_RS03615	COG0187	DNA topoisomerase II activity
M5005_RS03625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M5005_RS03645	COG0539	negative regulation of cytoplasmic translation
M5005_RS03680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M5005_RS03685	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
M5005_RS03695	COG0300	oxidoreductase activity
M5005_RS03700	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
M5005_RS03700	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M5005_RS03715	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M5005_RS03720	COG2384	SAM-dependent methyltransferase
M5005_RS03730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M5005_RS03735	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
M5005_RS03745	COG1088	dTDP-glucose 4,6-dehydratase activity
M5005_RS03750	COG1051	belongs to the nudix hydrolase family
M5005_RS03755	COG0628	permease
M5005_RS03760	COG0457	Tetratricopeptide repeat
M5005_RS03765	COG1293	RNA-binding protein homologous to eukaryotic snRNP
M5005_RS03780	COG1129	ABC transporter
M5005_RS03800	COG0488	(ABC) transporter
M5005_RS03805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M5005_RS03810	COG0022	dehydrogenase e1 component
M5005_RS03810	COG0508	dehydrogenase complex catalyzes the overall conversion of
M5005_RS03830	COG5492	domain, Protein
M5005_RS03835	COG0095	Lipoate-protein ligase
M5005_RS03840	COG3442	glutamine amidotransferase
M5005_RS03845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M5005_RS03850	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
M5005_RS03870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M5005_RS03880	COG0647	UMP catabolic process
M5005_RS03895	COG1518	maintenance of DNA repeat elements
M5005_RS03900	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
M5005_RS03915	COG0105	UTP biosynthetic process
M5005_RS03950	COG3715	PTS system
M5005_RS03955	COG3716	PTS system mannose fructose sorbose family IID component
M5005_RS03960	COG2972	Histidine kinase
M5005_RS03965	COG4753	response regulator
M5005_RS03965	COG2207	Transcriptional regulator
M5005_RS03970	COG1840	ABC-type Fe3 transport system, periplasmic component
M5005_RS03985	COG1011	Hydrolase
M5005_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
M5005_RS04005	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M5005_RS04065	COG1131	(ABC) transporter
M5005_RS04080	COG1396	sequence-specific DNA binding
M5005_RS04120	COG0285	dihydrofolate synthase activity
M5005_RS04140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M5005_RS04155	COG1176	ABC-type spermidine putrescine transport system, permease component I
M5005_RS04160	COG1177	transmembrane transport
M5005_RS04170	COG4565	transcriptional regulatory protein
M5005_RS04175	COG3290	protein histidine kinase activity
M5005_RS04180	COG3493	citrate carrier protein
M5005_RS04195	COG3700	Belongs to the class B bacterial acid phosphatase family
M5005_RS04200	COG0038	chloride channel
M5005_RS04210	COG0628	permease
M5005_RS04220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M5005_RS04235	COG1104	cysteine desulfurase activity
M5005_RS04250	COG2357	RelA SpoT domain protein
M5005_RS04260	COG0564	pseudouridine synthase activity
M5005_RS04265	COG0280	phosphate acetyltransferase
M5005_RS04285	COG1174	glycine betaine transport
M5005_RS04300	COG2233	PERMEase
M5005_RS04325	COG2890	protein-(glutamine-N5) methyltransferase activity
M5005_RS04355	COG1132	(ABC) transporter
M5005_RS04360	COG1132	(ABC) transporter
M5005_RS04380	COG3764	Sortase (surface protein transpeptidase)
M5005_RS04385	COG0346	lactoylglutathione lyase activity
M5005_RS04400	COG1272	protein, Hemolysin III
M5005_RS04420	COG0758	DNA mediated transformation
M5005_RS04425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M5005_RS04470	COG0511	ligase activity, forming carbon-carbon bonds
M5005_RS04475	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
M5005_RS04490	COG2851	Citrate transporter
M5005_RS04500	COG0511	ligase activity, forming carbon-carbon bonds
M5005_RS04505	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
M5005_RS04540	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
M5005_RS04560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M5005_RS04570	COG2188	Transcriptional regulator
M5005_RS04590	COG0488	(ABC) transporter
M5005_RS04600	COG0352	thiamine-phosphate diphosphorylase activity
M5005_RS04600	COG0351	phosphomethylpyrimidine kinase
M5005_RS04605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M5005_RS04610	COG1328	CTP reductase activity
M5005_RS04610	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M5005_RS04615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M5005_RS04645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M5005_RS04665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M5005_RS04670	COG4684	Psort location CytoplasmicMembrane, score
M5005_RS04675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M5005_RS04680	COG1079	Belongs to the binding-protein-dependent transport system permease family
M5005_RS04685	COG4603	Belongs to the binding-protein-dependent transport system permease family
M5005_RS04690	COG3845	ABC transporter
M5005_RS04695	COG1744	ABC transporter substrate-binding protein PnrA-like
M5005_RS04700	COG0295	cytidine deaminase activity
M5005_RS04705	COG2813	Specifically methylates the guanine in position
M5005_RS04720	COG5002	protein histidine kinase activity
M5005_RS04725	COG0745	RESPONSE REGULATOR receiver
M5005_RS04735	COG0704	Plays a role in the regulation of phosphate uptake
M5005_RS04750	COG0581	inorganic phosphate transmembrane transporter activity
M5005_RS04755	COG0573	inorganic phosphate transmembrane transporter activity
M5005_RS04765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M5005_RS04765	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
M5005_RS04770	COG0483	inositol monophosphate 1-phosphatase activity
M5005_RS04785	COG0196	riboflavin kinase activity
M5005_RS04815	COG1136	(ABC) transporter
M5005_RS04815	COG4591	ABC-type transport system involved in lipoprotein release permease component
M5005_RS04865	COG1115	amino acid carrier protein
M5005_RS04870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
M5005_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M5005_RS04885	COG1126	abc transporter atp-binding protein
M5005_RS04890	COG0765	amino acid transport
M5005_RS04895	COG2824	Alkylphosphonate utilization operon protein PhnA
M5005_RS04910	COG0469	pyruvate kinase activity
M5005_RS04925	COG1725	Transcriptional regulator
M5005_RS04930	COG1131	(ABC) transporter
M5005_RS05085	COG1783	phage Terminase large subunit
M5005_RS05190	COG1396	sequence-specific DNA binding
M5005_RS05230	COG0058	SHG alpha-glucan phosphorylase activity
M5005_RS05235	COG1640	4-alpha-glucanotransferase
M5005_RS05240	COG1609	Transcriptional regulator
M5005_RS05245	COG2182	Extracellular solute-binding protein
M5005_RS05250	COG1175	transmembrane transport
M5005_RS05255	COG3833	ABC-type maltose transport systems, permease component
M5005_RS05270	COG3833	ABC-type maltose transport systems, permease component
M5005_RS05275	COG1175	transmembrane transport
M5005_RS05285	COG0366	Alpha amylase catalytic
M5005_RS05290	COG2182	Extracellular solute-binding protein
M5005_RS05300	COG0657	acetylesterase activity
M5005_RS05305	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
M5005_RS05315	COG1696	Membrane protein involved in D-alanine export
M5005_RS05335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M5005_RS05340	COG1126	abc transporter atp-binding protein
M5005_RS05345	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M5005_RS05355	COG1447	Phosphotransferase system cellobiose-specific component IIA
M5005_RS05365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
M5005_RS05365	COG3711	transcriptional antiterminator
M5005_RS05375	COG2723	6-phospho-beta-galactosidase activity
M5005_RS05405	COG1187	pseudouridine synthase activity
M5005_RS05415	COG2814	Major facilitator Superfamily
M5005_RS05465	COG4109	DRTGG domain
M5005_RS05495	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
M5005_RS05495	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
M5005_RS05500	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M5005_RS05505	COG1956	GAF domain-containing protein
M5005_RS05525	COG0513	Belongs to the DEAD box helicase family
M5005_RS05530	COG0726	polysaccharide deacetylase
M5005_RS05550	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M5005_RS05555	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M5005_RS05560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M5005_RS05575	COG2801	Transposase and inactivated derivatives
M5005_RS05585	COG2801	Transposase and inactivated derivatives
M5005_RS05600	COG1476	TRANSCRIPTIONal
M5005_RS05615	COG4122	O-methyltransferase activity
M5005_RS05620	COG2223	nitrite transmembrane transporter activity
M5005_RS05635	COG1187	pseudouridine synthase activity
M5005_RS05680	COG0658	competence protein
M5005_RS05680	COG2333	competence protein COMEC
M5005_RS05685	COG1596	polysaccharide export
M5005_RS05685	COG1555	photosystem II stabilization
M5005_RS05690	COG0204	Acyl-transferase
M5005_RS05695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
M5005_RS05710	COG0513	Belongs to the DEAD box helicase family
M5005_RS05725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M5005_RS05740	COG0768	penicillin binding
M5005_RS05745	COG2116	formate transmembrane transporter activity
M5005_RS05755	COG1827	regulation of RNA biosynthetic process
M5005_RS05770	COG2217	Heavy metal translocating P-type atpase
M5005_RS05955	COG3723	Recombinational DNA repair protein, rece pathway
M5005_RS05975	COG3935	DnaD domain protein
M5005_RS06010	COG3561	AntA/AntB antirepressor
M5005_RS06020	COG1396	sequence-specific DNA binding
M5005_RS06035	COG0582	viral genome integration into host DNA
M5005_RS06050	COG2755	lipolytic protein G-D-S-L family
M5005_RS06065	COG0497	DNA recombination
M5005_RS06070	COG1438	arginine binding
M5005_RS06075	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M5005_RS06100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M5005_RS06105	COG0415	Belongs to the DNA photolyase family
M5005_RS06115	COG0765	amino acid transport
M5005_RS06120	COG4703	Protein of unknown function (DUF1797)
M5005_RS06125	COG0542	response to heat
M5005_RS06130	COG0494	nUDIX hydrolase
M5005_RS06145	COG3599	regulation of cell shape
M5005_RS06150	COG2302	S4 RNA-binding domain
M5005_RS06165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
M5005_RS06200	COG1217	gtp-binding protein TYPA
M5005_RS06205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M5005_RS06210	COG1940	carbohydrate kinase activity
M5005_RS06220	COG0783	Belongs to the Dps family
M5005_RS06235	COG4470	Protein conserved in bacteria
M5005_RS06245	COG3480	Lon protease (S16) C-terminal proteolytic domain
M5005_RS06255	COG0742	ribosomal rna small subunit methyltransferase
M5005_RS06265	COG0549	Belongs to the carbamate kinase family
M5005_RS06270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M5005_RS06275	COG1288	antiporter activity
M5005_RS06290	COG2235	arginine
M5005_RS06315	COG2972	Histidine kinase
M5005_RS06330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M5005_RS06335	COG0785	Cytochrome C biogenesis protein
M5005_RS06340	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
M5005_RS06345	COG1518	maintenance of DNA repeat elements
M5005_RS06405	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
M5005_RS06405	COG1605	Chorismate mutase
M5005_RS06425	COG2226	methyltransferase
M5005_RS06435	COG3250	beta-galactosidase activity
M5005_RS06440	COG4753	response regulator
M5005_RS06440	COG2207	Transcriptional regulator
M5005_RS06445	COG2972	Histidine kinase
M5005_RS06455	COG1653	transport
M5005_RS06460	COG0395	ABC-type sugar transport system, permease component
M5005_RS06465	COG1175	transmembrane transport
M5005_RS06470	COG1940	carbohydrate kinase activity
M5005_RS06475	COG2723	6-phospho-beta-galactosidase activity
M5005_RS06480	COG3525	Glycosyl hydrolase, family 20, catalytic domain
M5005_RS06495	COG0383	alpha-mannosidase activity
M5005_RS06585	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
M5005_RS06590	COG1739	Uncharacterized protein family UPF0029
M5005_RS06600	COG1098	S1 RNA binding domain
M5005_RS06610	COG2197	response regulator
M5005_RS06615	COG4585	Histidine kinase
M5005_RS06625	COG0515	serine threonine protein kinase
M5005_RS06625	COG2815	serine threonine protein kinase
M5005_RS06635	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M5005_RS06635	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M5005_RS06645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M5005_RS06665	COG0583	DNA-binding transcription factor activity
M5005_RS06670	COG0183	Belongs to the thiolase family
M5005_RS06675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M5005_RS06685	COG1028	Short-chain dehydrogenase reductase Sdr
M5005_RS06690	COG2610	gluconate transmembrane transporter activity
M5005_RS06705	COG0116	Belongs to the methyltransferase superfamily
M5005_RS06725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M5005_RS06730	COG3579	cysteine-type endopeptidase activity
M5005_RS06740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M5005_RS06745	COG1113	amino acid transport
M5005_RS06750	COG0492	ferredoxin-NADP+ reductase activity
M5005_RS06760	COG1126	abc transporter atp-binding protein
M5005_RS06770	COG0513	Belongs to the DEAD box helicase family
M5005_RS06780	COG0768	penicillin binding
M5005_RS06815	COG1131	(ABC) transporter
M5005_RS06840	COG0446	pyridine nucleotide-disulphide oxidoreductase
M5005_RS06845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M5005_RS06880	COG1755	Isoprenylcysteine carboxyl methyltransferase
M5005_RS06885	COG0656	L-ascorbic acid biosynthetic process
M5005_RS06895	COG1283	sodium-dependent phosphate transmembrane transporter activity
M5005_RS06915	COG0561	phosphatase activity
M5005_RS06920	COG2860	membrane
M5005_RS06970	COG2217	Heavy metal translocating P-type atpase
M5005_RS07000	COG2740	Nucleic-acid-binding protein implicated in transcription termination
M5005_RS07005	COG0195	Participates in both transcription termination and antitermination
M5005_RS07025	COG1705	Flagellar rod assembly protein muramidase FlgJ
M5005_RS07145	COG1783	phage Terminase large subunit
M5005_RS07260	COG4974	Belongs to the 'phage' integrase family
M5005_RS07280	COG4473	ABC transporter
M5005_RS07285	COG1131	(ABC) transporter
M5005_RS07290	COG0537	adenosine 5'-monophosphoramidase activity
M5005_RS07300	COG1316	TRANSCRIPTIONal
M5005_RS07310	COG0802	atpase or kinase
M5005_RS07315	COG2252	PERMEase
M5005_RS07320	COG0561	phosphatase activity
M5005_RS07330	COG3715	PTS system
M5005_RS07335	COG3716	PTS system mannose fructose sorbose family IID component
M5005_RS07360	COG0439	Biotin carboxylase
M5005_RS07375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M5005_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
M5005_RS07385	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M5005_RS07410	COG1024	Enoyl-CoA hydratase
M5005_RS07445	COG0588	phosphoglycerate mutase activity
M5005_RS07450	COG2261	transglycosylase associated protein
M5005_RS07475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M5005_RS07475	COG0574	Belongs to the PEP-utilizing enzyme family
M5005_RS07480	COG1335	isochorismatase
M5005_RS07490	COG0436	Aminotransferase
M5005_RS07500	COG0561	phosphatase activity
M5005_RS07505	COG0252	asparaginase activity
M5005_RS07520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M5005_RS07525	COG1129	ABC transporter
M5005_RS07540	COG1132	(ABC) transporter
M5005_RS07545	COG4988	ABC transporter
M5005_RS07550	COG1120	ATPase activity
M5005_RS07575	COG3942	CHAP domain
M5005_RS07575	COG1388	LysM domain
M5005_RS07605	COG5433	transposase activity
M5005_RS07610	COG1482	cell wall glycoprotein biosynthetic process
M5005_RS07615	COG1940	carbohydrate kinase activity
M5005_RS07625	COG1263	PTS System
M5005_RS07625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5005_RS07625	COG2190	(PTS) system
M5005_RS07630	COG1621	beta-fructofuranosidase activity
M5005_RS07635	COG1609	Transcriptional regulator
M5005_RS07655	COG2131	deaminase
M5005_RS07660	COG0006	proline dipeptidase activity
M5005_RS07700	COG1194	a g-specific adenine glycosylase
M5005_RS07710	COG3118	belongs to the thioredoxin family
M5005_RS07740	COG0681	Belongs to the peptidase S26 family
M5005_RS07745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M5005_RS07760	COG1882	Formate acetyltransferase
M5005_RS07765	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M5005_RS07780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
M5005_RS07785	COG2814	Major facilitator Superfamily
M5005_RS07790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M5005_RS07815	COG0789	Transcriptional regulator
M5005_RS07830	COG2081	HI0933 family
M5005_RS07840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
M5005_RS07845	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
M5005_RS07865	COG0456	acetyltransferase
M5005_RS07870	COG1214	PFAM Peptidase M22, glycoprotease
M5005_RS07885	COG0174	glutamine synthetase
M5005_RS07890	COG0789	Transcriptional regulator
M5005_RS07905	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
M5005_RS07930	COG5433	transposase activity
M5005_RS07970	COG0668	transmembrane transport
M5005_RS07980	COG4720	Psort location CytoplasmicMembrane, score
M5005_RS07985	COG0351	phosphomethylpyrimidine kinase
M5005_RS08030	COG1929	Belongs to the glycerate kinase type-1 family
M5005_RS08035	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
M5005_RS08065	COG0577	efflux transmembrane transporter activity
M5005_RS08070	COG1136	(ABC) transporter
M5005_RS08095	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M5005_RS08095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M5005_RS08100	COG1447	Phosphotransferase system cellobiose-specific component IIA
M5005_RS08150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M5005_RS08155	COG1476	TRANSCRIPTIONal
M5005_RS08175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M5005_RS08185	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
M5005_RS08200	COG1045	serine acetyltransferase
M5005_RS08215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M5005_RS08220	COG3037	sugar-specific permease SgaT UlaA
M5005_RS08230	COG3711	transcriptional antiterminator
M5005_RS08255	COG1846	Transcriptional regulator
M5005_RS08275	COG4589	Belongs to the CDS family
M5005_RS08285	COG1862	Preprotein translocase
M5005_RS08295	COG1523	belongs to the glycosyl hydrolase 13 family
M5005_RS08305	COG3842	ATPase activity
M5005_RS08345	COG1263	PTS System
M5005_RS08345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5005_RS08345	COG2190	(PTS) system
M5005_RS08350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M5005_RS08365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M5005_RS08370	COG0512	Glutamine amidotransferase of anthranilate synthase
M5005_RS08375	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M5005_RS08410	COG0601	transmembrane transport
M5005_RS08420	COG1122	ATPase activity
M5005_RS08440	COG0803	Belongs to the bacterial solute-binding protein 9 family
M5005_RS08450	COG5433	transposase activity
M5005_RS08480	COG3711	transcriptional antiterminator
M5005_RS08490	COG1705	Flagellar rod assembly protein muramidase FlgJ
M5005_RS08490	COG3942	CHAP domain
M5005_RS08495	COG2205	protein histidine kinase activity
M5005_RS08500	COG0745	RESPONSE REGULATOR receiver
M5005_RS08505	COG0577	efflux transmembrane transporter activity
M5005_RS08510	COG1136	(ABC) transporter
M5005_RS08560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M5005_RS08575	COG1882	Formate acetyltransferase
M5005_RS08580	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M5005_RS08585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
M5005_RS08590	COG1447	Phosphotransferase system cellobiose-specific component IIA
M5005_RS08595	COG2390	Transcriptional regulator
M5005_RS08600	COG1349	DNA-binding transcription factor activity
M5005_RS08605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
M5005_RS08620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M5005_RS08635	COG0564	pseudouridine synthase activity
M5005_RS08665	COG0542	response to heat
M5005_RS08670	COG4463	regulation of RNA biosynthetic process
M5005_RS08685	COG5433	transposase activity
M5005_RS08695	COG0450	alkyl hydroperoxide reductase
M5005_RS08710	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M5005_RS08720	COG3404	Formiminotransferase-cyclodeaminase
M5005_RS08735	COG0531	amino acid
M5005_RS08765	COG3590	peptidase
M5005_RS08770	COG0366	Alpha amylase catalytic
M5005_RS08775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
M5005_RS08775	COG1263	PTS System
M5005_RS08780	COG2188	Transcriptional regulator
M5005_RS08790	COG2514	catechol 2,3-dioxygenase activity
M5005_RS08800	COG0602	queuosine metabolic process
M5005_RS08815	COG1328	CTP reductase activity
M5005_RS08840	COG1393	Belongs to the ArsC family
M5005_RS08855	COG0519	Catalyzes the synthesis of GMP from XMP
M5005_RS08865	COG2814	Major facilitator Superfamily
M5005_RS08900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M5005_RS08905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M5005_RS08910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M5005_RS08990	COG1511	domain protein
M5005_RS09010	COG5433	transposase activity
M5005_RS09020	COG0305	Participates in initiation and elongation during chromosome replication
M5005_RS09050	COG1760	l-serine dehydratase
M5005_RS09055	COG1760	l-serine dehydratase
M5005_RS09060	COG0741	lytic transglycosylase activity
M5005_RS09065	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
M5005_RS09080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M5005_RS09090	COG0612	Peptidase, M16
M5005_RS09100	COG1215	transferase activity, transferring glycosyl groups
M5005_RS09130	COG0516	GMP reductase activity
M5005_RS09130	COG0517	IMP dehydrogenase activity
M5005_RS09140	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
M5005_RS09145	COG0488	(ABC) transporter
M5005_RS09185	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M5005_RS09190	COG1475	DNA binding