SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 Gene3D G3DSA:1.10.10.10 1 61 1.6E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 SUPERFAMILY SSF46785 1 60 9.02E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 PIRSF PIRSF037847 1 172 3.7E-62 T 23-04-2016 IPR026043 Transcription repressor NadR SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 Gene3D G3DSA:3.30.1340.20 67 171 1.6E-37 T 23-04-2016 IPR004173 3H domain GO:0036094 SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 Pfam PF02829 3H domain 73 169 4.2E-32 T 23-04-2016 IPR004173 3H domain GO:0036094 SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 SUPERFAMILY SSF75500 67 171 8.11E-35 T 23-04-2016 IPR004173 3H domain GO:0036094 SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 76 169 2.0E-48 T 23-04-2016 IPR004173 3H domain GO:0036094 SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 PANTHER PTHR40068 1 173 6.1E-46 T 23-04-2016 SPYM18_RS06195 bfa59dd7f621bc5da238c53eaf756120 173 Pfam PF08279 HTH domain 6 59 5.1E-14 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 PANTHER PTHR30146 4 330 5.7E-135 T 23-04-2016 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 52 1.1E-13 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 Gene3D G3DSA:3.40.50.2300 58 177 2.3E-38 T 23-04-2016 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 SUPERFAMILY SSF47413 3 63 1.35E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 Gene3D G3DSA:3.40.50.2300 178 310 4.1E-23 T 23-04-2016 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 Pfam PF13407 Periplasmic binding protein domain 66 306 7.5E-21 T 23-04-2016 IPR025997 Periplasmic binding protein SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 SMART SM00354 4 75 8.9E-27 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 SUPERFAMILY SSF53822 61 330 3.73E-48 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 PANTHER PTHR30146:SF40 4 330 5.7E-135 T 23-04-2016 SPYM18_RS02945 7ce9343e7daca0cbccd55535a269f5b9 331 Gene3D G3DSA:1.10.260.40 5 57 2.7E-20 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 PANTHER PTHR10724:SF8 1 111 1.3E-26 T 23-04-2016 SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 Gene3D G3DSA:2.40.50.140 2 80 6.3E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 Pfam PF00575 S1 RNA binding domain 2 73 9.3E-16 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 PANTHER PTHR10724 1 111 1.3E-26 T 23-04-2016 SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 SUPERFAMILY SSF50249 1 83 1.27E-19 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07035 dccf5514da6aff41ef6c22ae3153742e 125 SMART SM00316 2 73 5.4E-21 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 PANTHER PTHR41266 1 191 7.2E-56 T 23-04-2016 SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 Pfam PF01928 CYTH domain 4 182 6.2E-31 T 23-04-2016 IPR023577 CYTH domain SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 SMART SM01118 3 189 2.7E-20 T 23-04-2016 IPR023577 CYTH domain SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 SUPERFAMILY SSF55154 3 182 4.41E-27 T 23-04-2016 IPR033469 CYTH-like domain SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 Gene3D G3DSA:2.40.320.10 4 170 4.5E-12 T 23-04-2016 IPR023577 CYTH domain SPYM18_RS04680 0aa2da2188c4a049ea9393fbab3574d6 192 PIRSF PIRSF012526 1 190 7.8E-76 T 23-04-2016 IPR009195 Uncharacterised protein family YjbK KEGG: 00230+3.6.1.-|KEGG: 00332+3.6.1.-|KEGG: 00790+3.6.1.- SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 50 1.4E-13 T 23-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 374 425 1.3E-13 T 23-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 367 951 1.6E-243 T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Gene3D G3DSA:2.40.30.10 629 716 1.4E-21 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Pfam PF00009 Elongation factor Tu GTP binding domain 458 615 1.2E-34 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PRINTS PR00449 Transforming protein P21 ras signature 496 518 9.9E-5 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PRINTS PR00449 Transforming protein P21 ras signature 457 478 9.9E-5 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PRINTS PR00449 Transforming protein P21 ras signature 554 567 9.9E-5 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PRINTS PR00449 Transforming protein P21 ras signature 595 617 9.9E-5 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 ProSitePatterns PS01176 Initiation factor 2 signature. 905 927 - T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Pfam PF11987 Translation-initiation factor 2 740 844 2.6E-37 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PANTHER PTHR23115:SF184 802 952 2.8E-197 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PANTHER PTHR23115:SF184 438 778 2.8E-197 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Gene3D G3DSA:3.40.50.300 449 614 1.0E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 SUPERFAMILY SSF50447 629 708 1.39E-22 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Gene3D G3DSA:3.40.50.10050 754 833 4.5E-28 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Gene3D G3DSA:2.40.30.10 856 952 1.5E-32 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 SUPERFAMILY SSF50447 855 951 2.99E-26 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 457 613 1.9E-35 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PANTHER PTHR23115 802 952 2.8E-197 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 PANTHER PTHR23115 438 778 2.8E-197 T 23-04-2016 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 952 16.76 T 23-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 SUPERFAMILY SSF52156 731 861 1.57E-39 T 23-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 SPYM18_RS07425 a49ac8d17b24ed5edfea06a839585e3b 953 SUPERFAMILY SSF52540 438 627 8.27E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 PANTHER PTHR20982 1 185 2.0E-78 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 Gene3D G3DSA:1.10.132.20 66 183 3.5E-42 T 23-04-2016 IPR023584 Ribosome recycling factor domain SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 183 6.4E-70 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 Pfam PF01765 Ribosome recycling factor 20 183 7.1E-64 T 23-04-2016 IPR023584 Ribosome recycling factor domain SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 SUPERFAMILY SSF55194 3 183 2.62E-69 T 23-04-2016 IPR023584 Ribosome recycling factor domain SPYM18_RS02215 5d4639b5ff1a34710bca5bc90d0324c2 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.78 T 23-04-2016 IPR002661 Ribosome recycling factor GO:0006412 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 PANTHER PTHR11735:SF11 1 130 1.2E-41 T 23-04-2016 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 PANTHER PTHR11735 1 130 1.2E-41 T 23-04-2016 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 Pfam PF00814 Glycoprotease family 32 137 1.9E-30 T 23-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 SUPERFAMILY SSF53067 1 101 2.14E-26 T 23-04-2016 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 208 8.8E-52 T 23-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 Gene3D G3DSA:3.30.420.40 1 131 3.3E-39 T 23-04-2016 SPYM18_RS08360 23581e53e244eb120a17c2bde4b8067a 232 SUPERFAMILY SSF53067 110 206 1.19E-7 T 23-04-2016 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 248 40.474 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 PANTHER PTHR10291 13 249 2.4E-122 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 Gene3D G3DSA:3.40.1180.10 13 248 1.3E-98 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 193 210 - T 23-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 247 2.7E-82 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 SUPERFAMILY SSF64005 13 243 1.57E-89 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS08760 d31b2e02479e5887fd62e11d0585d5df 249 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 247 1.5E-80 T 23-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 Gene3D G3DSA:3.30.70.560 3 156 1.1E-56 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 133 1.8E-37 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 SUPERFAMILY SSF55083 1 158 2.09E-54 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 133 1.6E-49 T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 PANTHER PTHR20941 1 156 9.1E-68 T 23-04-2016 SPYM18_RS04575 5a8e1578239b1e8496d635917f69071e 166 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 23-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Pfam PF13192 Thioredoxin domain 124 194 8.2E-9 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 23-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Gene3D G3DSA:3.50.50.60 321 433 2.2E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 SUPERFAMILY SSF52833 103 194 1.9E-22 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Gene3D G3DSA:3.50.50.60 209 320 4.2E-24 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PANTHER PTHR22912:SF107 195 506 8.8E-169 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Gene3D G3DSA:3.40.30.10 3 93 9.4E-27 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Gene3D G3DSA:3.40.30.10 102 194 1.2E-35 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 4 510 1.9E-226 T 23-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 SUPERFAMILY SSF52833 3 100 2.39E-26 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 470 488 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 1.0E-63 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 460 482 4.0E-38 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 4.0E-38 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 4.0E-38 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 4.0E-38 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 4.0E-38 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 489 1.3E-45 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PANTHER PTHR22912 195 506 8.8E-169 T 23-04-2016 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 Gene3D G3DSA:3.50.50.60 434 507 1.5E-15 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 SUPERFAMILY SSF51905 209 506 2.49E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09155 416716f4b7d2cb783cbc7b4881ab3c9e 510 PIRSF PIRSF000238 2 510 6.4E-244 T 23-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 PANTHER PTHR33991 2 250 5.1E-49 T 23-04-2016 SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 24.155 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 TIGRFAM TIGR00613 reco: DNA repair protein RecO 8 242 2.4E-71 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 Gene3D G3DSA:2.40.50.140 1 79 1.5E-7 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 SUPERFAMILY SSF50249 2 78 6.0E-11 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 Pfam PF02565 Recombination protein O C terminal 83 237 1.5E-39 T 23-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 Pfam PF11967 Recombination protein O N terminal 1 73 6.1E-16 T 23-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal SPYM18_RS00250 f9df2ef03ed6dd4dd05b6e7a2333cbf9 251 SUPERFAMILY SSF57863 81 232 5.23E-38 T 23-04-2016 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 SUPERFAMILY SSF48013 5 132 1.31E-30 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PANTHER PTHR22807 18 438 7.0E-112 T 23-04-2016 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 13 437 7.8E-107 T 23-04-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 Gene3D G3DSA:1.10.940.10 6 159 4.9E-41 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 Gene3D G3DSA:3.40.50.150 235 438 8.3E-58 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 23-04-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 Pfam PF01029 NusB family 8 130 2.4E-27 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 435 4.7E-56 T 23-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 421 438 2.6E-28 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 2.6E-28 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 2.6E-28 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 2.6E-28 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 2.6E-28 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 SUPERFAMILY SSF53335 146 438 2.32E-62 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07070 0b5adcbf1462e1fca05b1ad53d44eab3 440 PANTHER PTHR22807:SF30 18 438 7.0E-112 T 23-04-2016 SPYM18_RS02000 685b00f9e110f0ca718d6829c62f1520 544 PANTHER PTHR30250:SF6 4 541 7.9E-139 T 23-04-2016 SPYM18_RS02000 685b00f9e110f0ca718d6829c62f1520 544 PANTHER PTHR30250 4 541 7.9E-139 T 23-04-2016 SPYM18_RS02000 685b00f9e110f0ca718d6829c62f1520 544 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 379 524 2.9E-23 T 23-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain SPYM18_RS02000 685b00f9e110f0ca718d6829c62f1520 544 Pfam PF01943 Polysaccharide biosynthesis protein 15 314 9.2E-31 T 23-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Gene3D G3DSA:3.30.1510.10 130 248 2.1E-57 T 23-04-2016 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Gene3D G3DSA:3.40.50.300 14 129 1.7E-149 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Gene3D G3DSA:3.40.50.300 249 442 1.7E-149 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 104 114 - T 23-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 SUPERFAMILY SSF52540 5 555 2.83E-241 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Gene3D G3DSA:3.10.410.10 444 533 1.7E-36 T 23-04-2016 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Pfam PF01268 Formate--tetrahydrofolate ligase 4 557 2.0E-268 T 23-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 PANTHER PTHR10025 2 556 0.0 T 23-04-2016 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 557 49.135 T 23-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS09180 021aa155b586b4dcf948849f421b1260 557 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 329 340 - T 23-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 3.3E-17 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 5.6E-48 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 PIRSF PIRSF039088 1 501 7.4E-239 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 PANTHER PTHR15184:SF3 1 485 8.2E-294 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 49.998 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 SUPERFAMILY SSF52540 95 370 1.09E-96 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 SUPERFAMILY SSF50615 10 94 2.22E-28 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Gene3D G3DSA:1.20.150.20 372 496 1.2E-50 T 23-04-2016 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Gene3D G3DSA:3.40.50.300 94 371 6.3E-114 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 PANTHER PTHR15184 1 485 8.2E-294 T 23-04-2016 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 496 8.3E-249 T 23-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 SUPERFAMILY SSF47917 372 497 2.54E-48 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 3.2E-71 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03530 9365084d5a9bfae4df832b1a7b9fd14c 502 Gene3D G3DSA:2.40.30.20 3 93 5.8E-35 T 23-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS07490 8901f633036111cb06f8121179baad94 174 PANTHER PTHR23091 5 174 6.7E-19 T 23-04-2016 SPYM18_RS07490 8901f633036111cb06f8121179baad94 174 Gene3D G3DSA:3.40.630.30 5 170 4.2E-28 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS07490 8901f633036111cb06f8121179baad94 174 Pfam PF00583 Acetyltransferase (GNAT) family 66 146 1.2E-13 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS07490 8901f633036111cb06f8121179baad94 174 SUPERFAMILY SSF55729 5 172 2.36E-23 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 PANTHER PTHR14503 2 44 6.0E-19 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-7 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.636 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 Pfam PF00468 Ribosomal protein L34 2 44 1.4E-22 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 1.1E-20 T 23-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01150 64aab8288b79288a0484b8a088016594 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 23-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 PANTHER PTHR23076 1 656 1.4E-298 T 23-04-2016 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Gene3D G3DSA:1.10.8.60 366 430 6.0E-27 T 23-04-2016 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 PANTHER PTHR23076:SF10 1 656 1.4E-298 T 23-04-2016 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Pfam PF01434 Peptidase family M41 418 623 2.5E-80 T 23-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 135 624 1.8E-224 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Pfam PF06480 FtsH Extracellular 14 127 3.2E-8 T 23-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 223 355 2.5E-44 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 ProSitePatterns PS00674 AAA-protein family signature. 326 344 - T 23-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 SUPERFAMILY SSF140990 438 629 4.32E-69 T 23-04-2016 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 12 638 36.564 T 23-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 Gene3D G3DSA:3.40.50.300 183 365 1.2E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 SMART SM00382 219 358 2.4E-23 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00060 63780247a600a20747ba3be95dcd3ac5 659 SUPERFAMILY SSF52540 183 426 3.26E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 Gene3D G3DSA:3.90.1640.10 339 529 4.3E-38 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 Gene3D G3DSA:3.30.450.20 72 138 1.8E-5 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 PANTHER PTHR12112 13 520 2.2E-73 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 PANTHER PTHR12112 605 617 2.2E-73 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 SUPERFAMILY SSF64182 339 633 1.83E-63 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 PANTHER PTHR12112:SF18 13 520 2.2E-73 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 PANTHER PTHR12112:SF18 605 617 2.2E-73 T 23-04-2016 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 PIRSF PIRSF026583 1 656 4.2E-252 T 23-04-2016 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 Pfam PF02272 DHHA1 domain 587 641 1.1E-8 T 23-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 SPYM18_RS09490 05455d72212860a2df5cd79ff13ebdba 658 Pfam PF01368 DHH family 340 495 2.2E-19 T 23-04-2016 IPR001667 DDH domain SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 Gene3D G3DSA:3.40.720.10 2 107 2.8E-69 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 Gene3D G3DSA:3.40.720.10 230 402 2.8E-69 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 Gene3D G3DSA:3.30.70.1250 108 226 2.6E-52 T 23-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 Hamap MF_00740 Phosphopentomutase [deoB]. 4 399 53.546 T 23-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 PANTHER PTHR21110:SF0 5 403 5.6E-142 T 23-04-2016 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 SUPERFAMILY SSF53649 3 108 2.91E-79 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 SUPERFAMILY SSF53649 227 402 2.91E-79 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 Pfam PF01676 Metalloenzyme superfamily 6 390 1.5E-39 T 23-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 SUPERFAMILY SSF143856 108 226 1.57E-47 T 23-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 396 1.6E-157 T 23-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 PIRSF PIRSF001491 3 403 6.1E-150 T 23-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 SPYM18_RS04095 16ac672c85f300caa345e8eb28a1b720 403 PANTHER PTHR21110 5 403 5.6E-142 T 23-04-2016 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 SUPERFAMILY SSF51998 10 804 7.02E-237 T 23-04-2016 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 Gene3D G3DSA:3.20.70.20 8 804 1.1E-278 T 23-04-2016 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 Pfam PF01228 Glycine radical 683 787 6.1E-32 T 23-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 12 805 6.3E-287 T 23-04-2016 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 PANTHER PTHR30191 1 805 0.0 T 23-04-2016 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 Pfam PF02901 Pyruvate formate lyase-like 13 666 1.0E-213 T 23-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 ProSitePatterns PS00850 Glycine radical domain signature. 776 784 - T 23-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPYM18_RS09040 ed7b98b7aa3a45a1373c0762a3ac975a 805 PANTHER PTHR30191:SF6 1 805 0.0 T 23-04-2016 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 PANTHER PTHR30589:SF0 2 259 5.4E-96 T 23-04-2016 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 252 17.381 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 3 245 1.8E-67 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 4 246 4.9E-76 T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 130 142 - T 23-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 SPYM18_RS02800 8831968c3224f8fa5ef5d59943fbef63 259 PANTHER PTHR30589 2 259 5.4E-96 T 23-04-2016 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 PANTHER PTHR13799:SF13 1 262 1.0E-76 T 23-04-2016 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 255 4.2E-58 T 23-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 Gene3D G3DSA:3.40.1390.30 1 112 3.6E-42 T 23-04-2016 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 239 2.0E-69 T 23-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 SUPERFAMILY SSF102705 1 260 2.22E-80 T 23-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 PANTHER PTHR13799 1 262 1.0E-76 T 23-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 SPYM18_RS04280 80e89941e9a4047b17ab5252b8d99bea 262 Gene3D G3DSA:3.40.1390.30 113 221 4.1E-40 T 23-04-2016 SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 52 235 2.1E-57 T 23-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 PANTHER PTHR12428 7 237 9.4E-53 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 PRINTS PR00701 60kDa inner membrane protein signature 118 141 1.5E-8 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 PRINTS PR00701 60kDa inner membrane protein signature 202 225 1.5E-8 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 239 28.981 T 23-04-2016 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes SPYM18_RS01140 8eed4409dc330174f91249c4b2dc2197 269 Pfam PF02096 60Kd inner membrane protein 54 235 1.6E-53 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS01930 3aa2677133aa1e47dea5a64247f76211 341 PANTHER PTHR10948 4 328 1.7E-83 T 23-04-2016 SPYM18_RS01930 3aa2677133aa1e47dea5a64247f76211 341 Gene3D G3DSA:3.30.420.10 179 314 4.4E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS01930 3aa2677133aa1e47dea5a64247f76211 341 SUPERFAMILY SSF53098 176 314 6.64E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS01930 3aa2677133aa1e47dea5a64247f76211 341 Gene3D G3DSA:1.10.10.60 7 46 6.2E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01930 3aa2677133aa1e47dea5a64247f76211 341 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 SMART SM00862 150 225 9.0E-25 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 Pfam PF00072 Response regulator receiver domain 5 114 4.5E-27 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 Gene3D G3DSA:3.40.50.2300 2 127 8.9E-39 T 23-04-2016 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 PANTHER PTHR26402 3 227 9.0E-91 T 23-04-2016 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 SUPERFAMILY SSF46894 132 226 3.97E-29 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 PANTHER PTHR26402:SF578 3 227 9.0E-91 T 23-04-2016 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 Gene3D G3DSA:1.10.10.10 134 227 3.4E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 224 3.4E-26 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 SMART SM00448 3 113 1.3E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS01505 8da555e210a64c4ce446c00aef9f4c51 228 SUPERFAMILY SSF52172 2 128 1.57E-39 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS07220 d5254d6cb04c7bf2e1aae78847e456e8 107 Hamap MF_00910 Cell division protein FtsL [ftsL]. 23 107 14.125 T 23-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SPYM18_RS07220 d5254d6cb04c7bf2e1aae78847e456e8 107 PANTHER PTHR41300 13 107 9.1E-18 T 23-04-2016 SPYM18_RS07220 d5254d6cb04c7bf2e1aae78847e456e8 107 Pfam PF04977 Septum formation initiator 33 103 1.7E-6 T 23-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SPYM18_RS07220 d5254d6cb04c7bf2e1aae78847e456e8 107 PANTHER PTHR41300:SF1 13 107 9.1E-18 T 23-04-2016 SPYM18_RS07220 d5254d6cb04c7bf2e1aae78847e456e8 107 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 25 106 1.2E-15 T 23-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PRINTS PR01002 Flagellar protein FlgJ signature 35 56 2.6E-9 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PRINTS PR01002 Flagellar protein FlgJ signature 122 140 2.6E-9 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PRINTS PR01002 Flagellar protein FlgJ signature 80 101 2.6E-9 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PRINTS PR01002 Flagellar protein FlgJ signature 102 121 2.6E-9 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 10 141 2.9E-18 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PANTHER PTHR33308 2 160 3.8E-21 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 Pfam PF05257 CHAP domain 183 267 1.3E-7 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 PANTHER PTHR33308:SF3 2 160 3.8E-21 T 23-04-2016 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 SMART SM00047 2 145 1.5E-22 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 Pfam PF08460 Bacterial SH3 domain 322 384 2.0E-7 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type SPYM18_RS07525 81ab17c0cd5af2eecaa431932d8527ae 401 SUPERFAMILY SSF54001 184 299 3.92E-6 T 23-04-2016 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 Pfam PF00005 ABC transporter 356 505 3.6E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 SUPERFAMILY SSF52540 335 573 5.33E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 PANTHER PTHR24221 9 571 1.1E-233 T 23-04-2016 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 SMART SM00382 365 551 7.9E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 Gene3D G3DSA:1.20.1560.10 11 321 1.1E-57 T 23-04-2016 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 SUPERFAMILY SSF90123 10 321 2.62E-60 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 Pfam PF00664 ABC transporter transmembrane region 23 291 3.4E-38 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 PANTHER PTHR24221:SF271 9 571 1.1E-233 T 23-04-2016 SPYM18_RS04795 2790c8d9f89975f2086b0d5da6b2337d 575 Gene3D G3DSA:3.40.50.300 339 569 4.4E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00345 a98c96941c7fa47706c41613e519849c 591 Pfam PF01757 Acyltransferase family 4 343 4.4E-22 T 23-04-2016 IPR002656 Acyltransferase 3 GO:0016747 SPYM18_RS00345 a98c96941c7fa47706c41613e519849c 591 SUPERFAMILY SSF52266 429 568 2.01E-5 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS00345 a98c96941c7fa47706c41613e519849c 591 PANTHER PTHR23028:SF53 14 347 3.1E-55 T 23-04-2016 SPYM18_RS00345 a98c96941c7fa47706c41613e519849c 591 PANTHER PTHR23028 14 347 3.1E-55 T 23-04-2016 SPYM18_RS05045 b7fe49b7b5d6a91382c3e02661845c18 270 Gene3D G3DSA:3.40.220.10 76 266 1.4E-55 T 23-04-2016 SPYM18_RS05045 b7fe49b7b5d6a91382c3e02661845c18 270 SMART SM00506 85 227 4.2E-23 T 23-04-2016 IPR002589 Macro domain SPYM18_RS05045 b7fe49b7b5d6a91382c3e02661845c18 270 SUPERFAMILY SSF52949 81 265 9.76E-51 T 23-04-2016 SPYM18_RS05045 b7fe49b7b5d6a91382c3e02661845c18 270 Pfam PF01661 Macro domain 102 227 1.7E-35 T 23-04-2016 IPR002589 Macro domain SPYM18_RS05045 b7fe49b7b5d6a91382c3e02661845c18 270 PANTHER PTHR11106 29 265 3.7E-62 T 23-04-2016 SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 SUPERFAMILY SSF54637 5 137 6.41E-48 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 137 3.6E-61 T 23-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 PANTHER PTHR30272 1 140 4.8E-77 T 23-04-2016 SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 Pfam PF07977 FabA-like domain 11 131 5.5E-36 T 23-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 140 33.745 T 23-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 SPYM18_RS07860 26af0aeed9213f5eb10af67561efe37c 140 Gene3D G3DSA:3.10.129.10 1 138 1.2E-55 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 327 9.0E-78 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 Gene3D G3DSA:1.10.10.10 2 81 2.3E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 322 25.624 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 56 2.5E-7 T 23-04-2016 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 SUPERFAMILY SSF46785 2 80 2.85E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 PANTHER PTHR30363 1 306 2.0E-69 T 23-04-2016 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 Pfam PF01628 HrcA protein C terminal domain 102 314 3.0E-27 T 23-04-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 SUPERFAMILY SSF55781 69 333 9.42E-29 T 23-04-2016 IPR029016 GAF domain-like SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 PANTHER PTHR30363:SF17 1 306 2.0E-69 T 23-04-2016 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 PIRSF PIRSF005485 1 333 6.7E-72 T 23-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 SPYM18_RS07925 117bf67aa627b0868685fee72fc12df0 344 Gene3D G3DSA:3.30.450.40 177 333 1.9E-10 T 23-04-2016 IPR029016 GAF domain-like SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 SUPERFAMILY SSF52402 195 413 2.87E-58 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 SUPERFAMILY SSF52317 10 235 4.03E-53 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 1.1E-7 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 1.1E-7 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 1.1E-7 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PANTHER PTHR11922 1 517 2.5E-287 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PANTHER PTHR11922:SF2 1 517 2.5E-287 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00097 Anthranilate synthase component II signature 175 188 5.7E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00097 Anthranilate synthase component II signature 84 95 5.7E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00097 Anthranilate synthase component II signature 57 66 5.7E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Gene3D G3DSA:3.40.50.620 221 395 2.3E-57 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 210 520 3.4E-150 T 23-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Gene3D G3DSA:3.40.50.880 8 220 3.7E-64 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 202 3.1E-74 T 23-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 2.5E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 2.5E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 2.5E-6 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 520 53.543 T 23-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Pfam PF02540 NAD synthase 221 255 3.0E-7 T 23-04-2016 IPR022310 NAD/GMP synthase SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Gene3D G3DSA:3.30.300.10 396 520 3.7E-51 T 23-04-2016 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Pfam PF00117 Glutamine amidotransferase class-I 15 197 1.6E-42 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 Pfam PF00958 GMP synthase C terminal domain 428 519 6.2E-44 T 23-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 SPYM18_RS04990 f3a3fda35a0659c8b62073b5ecf95ab2 520 SUPERFAMILY SSF54810 400 520 3.27E-50 T 23-04-2016 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 22.194 T 23-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 SUPERFAMILY SSF54995 1 95 3.92E-32 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 3.5E-26 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 Gene3D G3DSA:3.30.70.60 1 95 3.3E-34 T 23-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 Pfam PF01250 Ribosomal protein S6 3 93 1.4E-26 T 23-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS08175 2985f96d806d960d2bac8f1473500ba3 96 PANTHER PTHR21011 1 95 3.7E-26 T 23-04-2016 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Pfam PF13393 Histidyl-tRNA synthetase 8 312 7.8E-46 T 23-04-2016 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 PANTHER PTHR11476 1 425 1.9E-210 T 23-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 PIRSF PIRSF001549 1 420 4.9E-122 T 23-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Gene3D G3DSA:3.40.50.800 326 417 1.1E-26 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Pfam PF03129 Anticodon binding domain 331 417 1.0E-9 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 PANTHER PTHR11476:SF9 1 425 1.9E-210 T 23-04-2016 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Gene3D G3DSA:3.30.930.10 221 321 1.0E-100 T 23-04-2016 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Gene3D G3DSA:3.30.930.10 1 185 1.0E-100 T 23-04-2016 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 419 33.86 T 23-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 SUPERFAMILY SSF52954 328 418 5.73E-22 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 409 8.4E-157 T 23-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 SPYM18_RS09375 235b5ffe6ad99db8ee721eef8dc3180c 426 SUPERFAMILY SSF55681 3 320 4.59E-103 T 23-04-2016 SPYM18_RS06080 88524fe3066ad9f10b123b43540ac77e 320 PANTHER PTHR41265 2 315 3.5E-46 T 23-04-2016 SPYM18_RS06080 88524fe3066ad9f10b123b43540ac77e 320 PIRSF PIRSF007487 4 320 2.3E-104 T 23-04-2016 IPR021176 Competence-induced protein CoiA-like, bacterial SPYM18_RS06080 88524fe3066ad9f10b123b43540ac77e 320 PANTHER PTHR41265:SF1 2 315 3.5E-46 T 23-04-2016 SPYM18_RS06080 88524fe3066ad9f10b123b43540ac77e 320 Pfam PF06054 Competence protein CoiA-like family 19 265 1.2E-39 T 23-04-2016 IPR010330 Competence-induced protein CoiA-like SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 PANTHER PTHR22573:SF54 20 571 2.0E-229 T 23-04-2016 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 179 1.3E-40 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 496 546 1.2E-8 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Gene3D G3DSA:3.40.120.10 230 306 5.2E-22 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 SUPERFAMILY SSF53738 223 312 1.57E-18 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 23-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 SUPERFAMILY SSF53738 304 454 1.61E-30 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Gene3D G3DSA:3.30.310.50 480 571 3.7E-25 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 223 311 4.6E-22 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 PANTHER PTHR22573 20 571 2.0E-229 T 23-04-2016 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 SUPERFAMILY SSF53738 26 236 8.01E-46 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Gene3D G3DSA:3.40.120.10 307 454 4.0E-38 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 3.0E-23 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 Gene3D G3DSA:3.40.120.10 19 215 1.1E-58 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.2E-5 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 7.2E-5 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 SUPERFAMILY SSF55957 444 481 3.79E-15 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS05085 8f3e7c572333fcdb1e0d6e082bdfd2f8 572 SUPERFAMILY SSF55957 512 571 3.79E-15 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 9 121 6.6E-49 T 23-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 9 121 29.503 T 23-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 PANTHER PTHR12899 14 121 6.1E-45 T 23-04-2016 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 SUPERFAMILY SSF53137 10 119 1.16E-53 T 23-04-2016 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 10 121 1.3E-45 T 23-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00450 8b44ecc30ee0ad22bd0c867e7ea335be 121 Gene3D G3DSA:3.30.420.100 27 121 4.9E-40 T 23-04-2016 SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 Pfam PF01926 50S ribosome-binding GTPase 31 149 1.5E-21 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 Gene3D G3DSA:3.40.50.300 13 197 7.5E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 PANTHER PTHR11649 15 199 2.2E-54 T 23-04-2016 SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 30 191 6.3E-12 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 SUPERFAMILY SSF52540 23 197 8.5E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 17 199 29.068 T 23-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 SPYM18_RS04075 da25924917ff97320f8027052aae76ca 199 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 13 195 1.1E-72 T 23-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 SPYM18_RS04890 298511c0a1f7c550032305952bccc161 294 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 11 287 8.7E-71 T 23-04-2016 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPYM18_RS04890 298511c0a1f7c550032305952bccc161 294 PANTHER PTHR30201 9 294 2.1E-66 T 23-04-2016 SPYM18_RS04890 298511c0a1f7c550032305952bccc161 294 TIGRFAM TIGR03125 citrate_citG: triphosphoribosyl-dephospho-CoA synthase CitG 8 289 1.5E-110 T 23-04-2016 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPYM18_RS04890 298511c0a1f7c550032305952bccc161 294 Hamap MF_00397 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase [citG]. 1 294 161.177 T 23-04-2016 IPR017551 Triphosphoribosyl-dephospho-CoA synthase CitG GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 PANTHER PTHR41299 1 210 2.6E-39 T 23-04-2016 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 Gene3D G3DSA:2.60.120.320 123 207 5.3E-5 T 23-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 SMART SM00983 139 202 4.3E-18 T 23-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 Gene3D G3DSA:3.40.50.10240 5 111 5.4E-22 T 23-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 140 201 3.4E-8 T 23-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 PANTHER PTHR41299:SF1 1 210 2.6E-39 T 23-04-2016 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 16 204 8.9E-49 T 23-04-2016 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 SUPERFAMILY SSF63999 1 127 1.16E-30 T 23-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 SPYM18_RS01225 babf51af223cee72dfecf39c37c5b693 210 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 110 2.6E-15 T 23-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PRINTS PR00046 Major sigma-70 factor signature 328 343 1.4E-31 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PRINTS PR00046 Major sigma-70 factor signature 343 354 1.4E-31 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PRINTS PR00046 Major sigma-70 factor signature 183 191 1.4E-31 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PRINTS PR00046 Major sigma-70 factor signature 307 319 1.4E-31 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PRINTS PR00046 Major sigma-70 factor signature 159 172 1.4E-31 T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Pfam PF04539 Sigma-70 region 3 214 290 2.4E-30 T 23-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 131 367 1.9E-125 T 23-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PANTHER PTHR30603:SF0 4 368 1.9E-200 T 23-04-2016 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 368 33.043 T 23-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 SUPERFAMILY SSF88659 265 366 1.14E-28 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Pfam PF03979 Sigma-70 factor, region 1.1 13 86 2.1E-7 T 23-04-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Gene3D G3DSA:1.10.10.10 297 368 4.6E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 132 356 6.8E-38 T 23-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 SUPERFAMILY SSF88946 96 205 1.57E-52 T 23-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Pfam PF04545 Sigma-70, region 4 303 356 2.4E-19 T 23-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 159 172 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Pfam PF00140 Sigma-70 factor, region 1.2 97 128 2.0E-14 T 23-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Gene3D G3DSA:1.10.10.10 208 259 2.4E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Gene3D G3DSA:1.10.601.10 30 204 6.3E-73 T 23-04-2016 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 328 354 - T 23-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 SUPERFAMILY SSF88659 208 282 1.87E-21 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 PANTHER PTHR30603 4 368 1.9E-200 T 23-04-2016 SPYM18_RS03635 b7f66971b223a100f2ebd57f1ff7bb4a 369 Pfam PF04542 Sigma-70 region 2 135 204 5.3E-23 T 23-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Gene3D G3DSA:1.10.340.30 24 125 1.4E-42 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Gene3D G3DSA:1.10.1670.10 126 227 1.9E-32 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 SUPERFAMILY SSF55811 223 370 6.08E-20 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 38 169 4.1E-18 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Gene3D G3DSA:3.90.79.10 233 373 4.8E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 PANTHER PTHR10359:SF1 3 330 8.5E-95 T 23-04-2016 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 SUPERFAMILY SSF48150 8 225 1.3E-68 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Pfam PF14815 NUDIX domain 238 366 2.2E-16 T 23-04-2016 IPR029119 MutY, C-terminal SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 PANTHER PTHR10359 3 330 8.5E-95 T 23-04-2016 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 10 271 5.3E-95 T 23-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 Pfam PF00633 Helix-hairpin-helix motif 103 131 6.1E-9 T 23-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 SPYM18_RS08185 990f440c876f661cfee76dea905e4020 374 SMART SM00478 42 193 4.0E-44 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 SUPERFAMILY SSF52540 169 430 8.36E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Gene3D G3DSA:2.40.50.140 44 118 1.8E-17 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 640 1.8E-238 T 23-04-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Gene3D G3DSA:3.40.50.300 245 432 1.0E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Pfam PF00270 DEAD/DEAH box helicase 254 411 5.3E-16 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 SMART SM00490 486 567 8.7E-22 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 SUPERFAMILY SSF52540 371 580 3.31E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031:SF249 108 229 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031:SF249 283 580 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031:SF249 253 266 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031:SF249 603 648 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Pfam PF17191 RecG wedge domain 10 157 8.8E-15 T 23-04-2016 IPR033454 RecG, wedge domain SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Pfam PF00271 Helicase conserved C-terminal domain 457 566 3.5E-20 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 SUPERFAMILY SSF50249 3 161 1.03E-30 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031 108 229 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031 283 580 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031 253 266 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 PANTHER PTHR24031 603 648 5.1E-118 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Gene3D G3DSA:3.40.50.300 433 615 1.0E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 Gene3D G3DSA:1.10.150.20 4 33 8.7E-4 T 23-04-2016 SPYM18_RS08015 2e0a00d056688aaa3746afd03f007a21 671 SMART SM00487 249 444 1.3E-28 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS04940 64ed26ffe9960d29973ad2ce08b19e5a 192 Hamap MF_00398 Probable apo-citrate lyase phosphoribosyl-dephospho-CoA transferase [citX]. 3 182 34.997 T 23-04-2016 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 SPYM18_RS04940 64ed26ffe9960d29973ad2ce08b19e5a 192 TIGRFAM TIGR03124 citrate_citX: holo-ACP synthase CitX 12 177 2.2E-56 T 23-04-2016 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 SPYM18_RS04940 64ed26ffe9960d29973ad2ce08b19e5a 192 Pfam PF03802 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase 13 177 2.1E-50 T 23-04-2016 IPR005551 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase GO:0051191 SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 SUPERFAMILY SSF55920 127 281 2.09E-48 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 Hamap MF_01974 Methionine aminopeptidase [map]. 2 280 34.679 T 23-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 Gene3D G3DSA:3.90.230.10 1 281 2.8E-76 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 Pfam PF00557 Metallopeptidase family M24 128 271 1.8E-28 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 Pfam PF00557 Metallopeptidase family M24 12 100 1.1E-8 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 SUPERFAMILY SSF55920 1 100 1.13E-18 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 PANTHER PTHR10804:SF108 128 283 7.4E-163 T 23-04-2016 SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 PANTHER PTHR10804:SF108 1 101 7.4E-163 T 23-04-2016 SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 PANTHER PTHR10804 128 283 7.4E-163 T 23-04-2016 SPYM18_RS05910 43a39e6c1d65f4ebacef9bf61225b9dc 286 PANTHER PTHR10804 1 101 7.4E-163 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 SMART SM00228 301 387 3.4E-7 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 345 357 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 121 133 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 183 207 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PRINTS PR00834 HtrA/DegQ protease family signature 142 162 6.1E-35 T 23-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 SUPERFAMILY SSF50494 56 293 2.74E-55 T 23-04-2016 IPR009003 Peptidase S1, PA clan SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 Gene3D G3DSA:2.30.42.10 304 401 3.8E-17 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PANTHER PTHR22939 19 396 1.0E-91 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 Gene3D G3DSA:2.40.10.10 56 172 4.6E-27 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 Pfam PF13180 PDZ domain 301 396 1.6E-21 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 Gene3D G3DSA:2.40.10.10 175 303 9.2E-41 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 Pfam PF13365 Trypsin-like peptidase domain 109 254 2.4E-29 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 PANTHER PTHR22939:SF79 19 396 1.0E-91 T 23-04-2016 SPYM18_RS09640 b1bb0871d8d70e74f1d7b1bd00f371fd 407 SUPERFAMILY SSF50156 329 399 3.19E-13 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 Gene3D G3DSA:1.20.1250.20 15 195 8.6E-24 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 2.1E-9 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 18 42 2.1E-9 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 2.1E-9 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 2.1E-9 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 204 222 2.1E-9 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 PANTHER PTHR23501 10 445 1.6E-70 T 23-04-2016 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 Pfam PF07690 Major Facilitator Superfamily 20 406 5.3E-39 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 SUPERFAMILY SSF103473 5 201 1.96E-52 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 SUPERFAMILY SSF103473 245 447 1.96E-52 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS02745 f873c64bc1401603c9cef5aee53b13d3 455 Gene3D G3DSA:1.20.1250.20 262 448 4.4E-15 T 23-04-2016 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 SUPERFAMILY SSF53335 66 240 7.45E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 SUPERFAMILY SSF53335 8 38 7.45E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PANTHER PTHR13370:SF4 180 250 1.4E-13 T 23-04-2016 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PANTHER PTHR13370 180 250 1.4E-13 T 23-04-2016 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 200 218 5.8E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 181 198 5.8E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 22 36 5.8E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 223 243 5.8E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 Pfam PF01555 DNA methylase 180 239 9.9E-19 T 23-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 SPYM18_RS06400 330514806b65ef242fa0a7840aee88d9 251 Gene3D G3DSA:3.40.50.150 15 242 2.3E-30 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07825 ae817a9c92103636737d6f71e47a724b 269 PANTHER PTHR32502:SF10 1 269 1.4E-146 T 23-04-2016 SPYM18_RS07825 ae817a9c92103636737d6f71e47a724b 269 PANTHER PTHR32502 1 269 1.4E-146 T 23-04-2016 SPYM18_RS07825 ae817a9c92103636737d6f71e47a724b 269 Pfam PF03609 PTS system sorbose-specific iic component 6 241 2.2E-71 T 23-04-2016 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 Hamap MF_00173 Arginine repressor [argR]. 1 152 54.491 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 SUPERFAMILY SSF55252 79 147 1.7E-21 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 SUPERFAMILY SSF46785 1 62 4.63E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PRINTS PR01467 Bacterial arginine repressor signature 118 133 5.8E-20 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PRINTS PR01467 Bacterial arginine repressor signature 88 101 5.8E-20 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PRINTS PR01467 Bacterial arginine repressor signature 38 53 5.8E-20 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PRINTS PR01467 Bacterial arginine repressor signature 22 35 5.8E-20 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PANTHER PTHR34471 1 153 5.0E-41 T 23-04-2016 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 Pfam PF01316 Arginine repressor, DNA binding domain 3 65 9.1E-23 T 23-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 Gene3D G3DSA:1.10.10.10 10 61 6.2E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 PANTHER PTHR34471:SF1 1 153 5.0E-41 T 23-04-2016 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 1.8E-21 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 91 127 6.0E-15 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS06750 6aaa50056a9c4fdc3958e23e423f7449 157 Gene3D G3DSA:3.30.1360.40 72 148 1.7E-25 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SMART SM00322 555 620 4.9E-11 T 23-04-2016 IPR004087 K Homology domain GO:0003676 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF46915 236 323 6.28E-13 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 PANTHER PTHR11252 1 709 0.0 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF01138 3' exoribonuclease family, domain 1 326 459 8.7E-13 T 23-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 4.9E-18 T 23-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 694 8.2E-297 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF55666 143 233 3.14E-29 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF50249 623 706 1.14E-20 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 696 29.075 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Gene3D G3DSA:1.10.10.400 228 313 7.6E-34 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF00575 S1 RNA binding domain 622 693 4.0E-18 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF00013 KH domain 560 615 8.8E-9 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Gene3D G3DSA:3.30.230.70 5 222 7.6E-82 T 23-04-2016 IPR027408 PNPase/RNase PH domain SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Gene3D G3DSA:3.30.230.70 314 546 6.4E-82 T 23-04-2016 IPR027408 PNPase/RNase PH domain SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF54211 7 142 3.09E-44 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF54791 559 643 2.32E-20 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SMART SM00316 623 693 1.8E-23 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Gene3D G3DSA:2.40.50.140 624 695 3.0E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF55666 453 551 1.96E-28 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 1.8E-13 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF03725 3' exoribonuclease family, domain 2 462 532 1.1E-7 T 23-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 323 4.3E-11 T 23-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 PIRSF PIRSF005499 1 710 1.9E-281 T 23-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 SUPERFAMILY SSF54211 297 490 1.77E-41 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 PANTHER PTHR11252:SF0 1 709 0.0 T 23-04-2016 SPYM18_RS08685 91d0522ebe5c13bc71035f142c2ed7f2 710 Gene3D G3DSA:3.30.1370.10 554 623 5.1E-23 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 PANTHER PTHR11142 1 249 4.2E-88 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 Gene3D G3DSA:3.30.70.580 1 105 1.1E-34 T 23-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 SUPERFAMILY SSF55120 1 249 4.03E-82 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 247 34.333 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 242 3.2E-65 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 Gene3D G3DSA:3.30.70.660 109 248 3.8E-44 T 23-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 Pfam PF01416 tRNA pseudouridine synthase 144 247 6.8E-27 T 23-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 Pfam PF01416 tRNA pseudouridine synthase 6 104 4.7E-12 T 23-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS08470 51252ee2fdf93846bd92f120b2540fb9 249 PIRSF PIRSF001430 1 249 5.5E-77 T 23-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS01665 4cf8622f2ff01a83386ae4be3f089174 177 Gene3D G3DSA:1.10.443.10 10 172 4.9E-36 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS01665 4cf8622f2ff01a83386ae4be3f089174 177 PANTHER PTHR30349 2 176 6.8E-50 T 23-04-2016 SPYM18_RS01665 4cf8622f2ff01a83386ae4be3f089174 177 PANTHER PTHR30349:SF19 2 176 6.8E-50 T 23-04-2016 SPYM18_RS01665 4cf8622f2ff01a83386ae4be3f089174 177 SUPERFAMILY SSF56349 7 174 6.47E-40 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS01665 4cf8622f2ff01a83386ae4be3f089174 177 Pfam PF00589 Phage integrase family 12 163 1.6E-26 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS04225 29d52f929cc9ba2621430ccc195f38cf 302 Pfam PF03595 Voltage-dependent anion channel 13 285 2.8E-11 T 23-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 SPYM18_RS04225 29d52f929cc9ba2621430ccc195f38cf 302 PANTHER PTHR37955 1 302 1.1E-54 T 23-04-2016 SPYM18_RS04225 29d52f929cc9ba2621430ccc195f38cf 302 PANTHER PTHR37955:SF1 1 302 1.1E-54 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.30.30.30 39 98 2.3E-12 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:1.20.1270.10 502 573 4.0E-18 T 23-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 SUPERFAMILY SSF100920 354 510 4.97E-60 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 608 36.051 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 2.6E-282 T 23-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 SUPERFAMILY SSF100934 477 576 4.05E-11 T 23-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.90.640.10 200 285 2.3E-30 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.30.420.40 165 199 4.7E-34 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.30.420.40 289 331 4.7E-34 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.30.420.40 99 164 4.8E-58 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:3.30.420.40 3 38 4.8E-58 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PANTHER PTHR19375 2 607 0.0 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 SUPERFAMILY SSF53067 1 157 5.18E-56 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Pfam PF00012 Hsp70 protein 4 74 7.1E-25 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Pfam PF00012 Hsp70 protein 76 574 2.4E-215 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 23-04-2016 IPR018181 Heat shock protein 70, conserved site SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.5E-78 T 23-04-2016 IPR013126 Heat shock protein 70 family SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 SUPERFAMILY SSF53067 160 351 3.58E-66 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 PANTHER PTHR19375:SF173 2 607 0.0 T 23-04-2016 SPYM18_RS07915 e65fc00882d593a08acc30e0fb6bf233 608 Gene3D G3DSA:2.60.34.10 360 501 3.4E-70 T 23-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 PANTHER PTHR11601:SF17 4 405 2.7E-201 T 23-04-2016 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 Gene3D G3DSA:3.40.640.10 38 281 4.8E-85 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 404 1.2E-179 T 23-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 PIRSF PIRSF005572 21 405 2.7E-49 T 23-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 SUPERFAMILY SSF53383 3 400 6.45E-127 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 Gene3D G3DSA:3.90.1150.10 282 397 3.1E-29 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 PANTHER PTHR11601 4 405 2.7E-201 T 23-04-2016 SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 214 233 - T 23-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPYM18_RS01315 3fc6e76bdef8bab9425872651d8db5ed 408 Pfam PF00266 Aminotransferase class-V 24 393 7.2E-152 T 23-04-2016 IPR000192 Aminotransferase class V domain SPYM18_RS05755 f7fdd8771b5d5759bd94f916d3e3b007 47 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 9 47 3.5E-17 T 23-04-2016 IPR021008 Protein of unknown function DUF3687 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 Gene3D G3DSA:3.40.1190.10 1 292 3.9E-86 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 Pfam PF08245 Mur ligase middle domain 45 267 1.5E-10 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 413 2.1E-124 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 PIRSF PIRSF001563 1 419 3.6E-119 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 SUPERFAMILY SSF53244 294 415 3.11E-21 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 PANTHER PTHR11136:SF0 1 423 1.1E-109 T 23-04-2016 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 Gene3D G3DSA:3.90.190.20 294 417 3.2E-23 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 SUPERFAMILY SSF53623 1 292 3.21E-85 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04555 e85cc5029068847f5106063ced62792f 425 PANTHER PTHR11136 1 423 1.1E-109 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 SUPERFAMILY SSF52374 2 314 6.97E-100 T 23-04-2016 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 447 37.383 T 23-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 SUPERFAMILY SSF47323 327 446 1.31E-31 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 Pfam PF09190 DALR domain 344 396 7.7E-17 T 23-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 314 3.0E-132 T 23-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 PANTHER PTHR10890 1 444 7.1E-222 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 7.7E-29 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 7.7E-29 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 7.7E-29 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 7.7E-29 T 23-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 Gene3D G3DSA:1.20.120.640 309 390 3.7E-17 T 23-04-2016 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 Gene3D G3DSA:3.40.50.620 20 307 1.0E-106 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 446 1.1E-170 T 23-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 SPYM18_RS08665 e538f4b174cdd712e62d84f646a046f3 447 SMART SM00840 344 398 4.8E-16 T 23-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 PANTHER PTHR10025 1 555 0.0 T 23-04-2016 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Gene3D G3DSA:3.10.410.10 444 532 1.3E-36 T 23-04-2016 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 23-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 48.263 T 23-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Gene3D G3DSA:3.30.1510.10 129 246 5.9E-56 T 23-04-2016 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 23-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Gene3D G3DSA:3.40.50.300 248 441 5.8E-141 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Gene3D G3DSA:3.40.50.300 13 128 5.8E-141 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 Pfam PF01268 Formate--tetrahydrofolate ligase 2 556 1.6E-259 T 23-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 SPYM18_RS05030 80ca082e696297e0f38d9cb4fe6c44c6 556 SUPERFAMILY SSF52540 4 554 9.96E-238 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02050 8e41c91cd6d4ad89bd0ed4e218118ce1 209 Gene3D G3DSA:3.20.20.380 1 207 3.5E-70 T 23-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 SPYM18_RS02050 8e41c91cd6d4ad89bd0ed4e218118ce1 209 PANTHER PTHR12598:SF0 1 206 1.0E-60 T 23-04-2016 SPYM18_RS02050 8e41c91cd6d4ad89bd0ed4e218118ce1 209 PANTHER PTHR12598 1 206 1.0E-60 T 23-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 SPYM18_RS02050 8e41c91cd6d4ad89bd0ed4e218118ce1 209 SUPERFAMILY SSF110395 1 209 3.79E-57 T 23-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 SPYM18_RS02050 8e41c91cd6d4ad89bd0ed4e218118ce1 209 Pfam PF03932 CutC family 1 208 9.0E-87 T 23-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 SPYM18_RS06510 d20556b4cbd8f1e69ae7f1b5395dcdc9 315 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 283 314 5.1E-5 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 23-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 Gene3D G3DSA:3.50.50.60 105 296 3.6E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 3.9E-39 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 3.9E-39 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.9E-39 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 3.9E-39 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.9E-39 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 SUPERFAMILY SSF51905 1 300 1.17E-56 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PANTHER PTHR22912 1 302 4.7E-134 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PANTHER PTHR22912:SF48 1 302 4.7E-134 T 23-04-2016 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 Gene3D G3DSA:3.50.50.60 1 104 5.0E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 6.5E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 300 1.7E-116 T 23-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS07185 8fbfcd3d1359d2cdee182e0fdcee7cc4 305 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 2.3E-72 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 SUPERFAMILY SSF52540 6 238 7.74E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 PANTHER PTHR24220 7 245 4.9E-136 T 23-04-2016 SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 PIRSF PIRSF039085 2 245 4.4E-113 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 Gene3D G3DSA:3.40.50.300 6 241 9.7E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 Pfam PF00005 ABC transporter 21 169 1.6E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 SMART SM00382 30 238 2.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05770 8b65f3fde66c032d923eb25d914f16f9 246 PANTHER PTHR24220:SF327 7 245 4.9E-136 T 23-04-2016 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 PANTHER PTHR19211 1 509 8.8E-301 T 23-04-2016 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Pfam PF12848 ABC transporter 229 314 6.8E-20 T 23-04-2016 IPR032781 ABC-transporter extension domain SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Gene3D G3DSA:3.40.50.300 326 503 1.3E-33 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Gene3D G3DSA:3.40.50.300 123 279 3.1E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Gene3D G3DSA:3.40.50.300 2 90 3.1E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 SMART SM00382 28 238 1.0E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 SMART SM00382 349 514 1.6E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Pfam PF00005 ABC transporter 343 469 6.6E-20 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 Pfam PF00005 ABC transporter 20 190 1.7E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 SUPERFAMILY SSF52540 305 506 4.69E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 ProSitePatterns PS00211 ABC transporters family signature. 441 455 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 SUPERFAMILY SSF52540 4 243 2.2E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05000 bf172d195d98cba5dfc165cbc41fa947 514 PANTHER PTHR19211:SF65 1 509 8.8E-301 T 23-04-2016 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 4.7E-28 T 23-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 23-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 3.8E-32 T 23-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 35.852 T 23-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 161 8.0E-68 T 23-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 SUPERFAMILY SSF54768 8 75 5.65E-25 T 23-04-2016 SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 SUPERFAMILY SSF54211 79 157 8.85E-25 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 Gene3D G3DSA:3.30.160.20 9 71 2.0E-32 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 Gene3D G3DSA:3.30.230.10 75 157 6.2E-31 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS00455 1da175acf8d4c063b96c669872dbe7e6 164 PANTHER PTHR13718 9 160 7.6E-74 T 23-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 PANTHER PTHR32282:SF5 75 680 3.7E-183 T 23-04-2016 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 Pfam PF00912 Transglycosylase 151 317 7.6E-57 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 158 697 7.4E-162 T 23-04-2016 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 Gene3D G3DSA:1.10.3810.10 150 319 9.4E-66 T 23-04-2016 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 Gene3D G3DSA:3.40.710.10 320 731 4.7E-93 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 PANTHER PTHR32282 75 680 3.7E-183 T 23-04-2016 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 Pfam PF00905 Penicillin binding protein transpeptidase domain 417 680 1.3E-35 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 SUPERFAMILY SSF56601 299 321 3.3E-93 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 SUPERFAMILY SSF56601 354 715 3.3E-93 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS09080 7ad6c22b40e1ac3fac463f15870d79b2 778 SUPERFAMILY SSF53955 137 339 3.66E-65 T 23-04-2016 IPR023346 Lysozyme-like domain SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946:SF7 609 832 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946:SF7 240 265 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946:SF7 4 207 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946:SF7 471 575 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946:SF7 288 453 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 53 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 833 0.0 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 SUPERFAMILY SSF47323 653 832 1.16E-29 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 832 22.375 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Gene3D G3DSA:1.10.730.10 639 768 4.7E-36 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Pfam PF08264 Anticodon-binding domain of tRNA 684 794 1.0E-15 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 401 1.5E-65 T 23-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 609 636 1.3E-6 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 414 572 9.8E-6 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 SUPERFAMILY SSF50677 226 412 8.06E-54 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Gene3D G3DSA:3.40.50.620 3 222 1.6E-158 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Gene3D G3DSA:3.40.50.620 422 574 1.6E-158 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Gene3D G3DSA:3.40.50.620 609 638 1.6E-158 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Gene3D G3DSA:3.90.740.10 223 421 1.1E-60 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946 609 832 0.0 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946 240 265 0.0 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946 4 207 0.0 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946 471 575 0.0 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PANTHER PTHR11946 288 453 0.0 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 486 504 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 9.4E-55 T 23-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 SUPERFAMILY SSF52374 413 658 1.31E-136 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 SUPERFAMILY SSF52374 3 226 1.31E-136 T 23-04-2016 SPYM18_RS00935 b7df8b87c7b2ab3985eac17d9de5f25e 833 Pfam PF09334 tRNA synthetases class I (M) 40 162 2.5E-16 T 23-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS08970 4307fbf3f6a60e0193a5807bf7d72f56 405 Pfam PF02687 FtsX-like permease family 286 398 1.4E-20 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS08970 4307fbf3f6a60e0193a5807bf7d72f56 405 PANTHER PTHR30572 1 405 1.2E-78 T 23-04-2016 SPYM18_RS08970 4307fbf3f6a60e0193a5807bf7d72f56 405 Pfam PF12704 MacB-like periplasmic core domain 18 245 5.7E-25 T 23-04-2016 IPR025857 MacB-like periplasmic core domain SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 Pfam PF01479 S4 domain 1 47 1.9E-15 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 Pfam PF00849 RNA pseudouridylate synthase 61 194 2.0E-20 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 SMART SM00363 1 64 1.6E-16 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 PANTHER PTHR21600:SF2 1 240 7.2E-81 T 23-04-2016 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 Gene3D G3DSA:3.10.290.10 1 63 1.7E-25 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 23-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 PANTHER PTHR21600 1 240 7.2E-81 T 23-04-2016 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 SUPERFAMILY SSF55174 1 55 9.22E-16 T 23-04-2016 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 225 4.1E-47 T 23-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS01910 418164d3cec0a6ab94194dd86eebd03d 240 SUPERFAMILY SSF55120 45 237 1.87E-44 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PANTHER PTHR11751:SF306 14 392 3.7E-143 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 SUPERFAMILY SSF53383 1 392 2.02E-106 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 5.0E-13 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 230 254 5.0E-13 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 116 137 5.0E-13 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 5.0E-13 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 PANTHER PTHR11751 14 392 3.7E-143 T 23-04-2016 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 23-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 Gene3D G3DSA:3.40.640.10 45 272 7.5E-71 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 Pfam PF00155 Aminotransferase class I and II 32 387 4.0E-73 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPYM18_RS03040 2ed84a208d86866b3cd96f7ba8147a89 397 Gene3D G3DSA:3.90.1150.10 273 393 4.8E-38 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PANTHER PTHR30477 1 305 6.6E-119 T 23-04-2016 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 SUPERFAMILY SSF53807 15 305 2.94E-75 T 23-04-2016 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PANTHER PTHR30477:SF10 1 305 6.6E-119 T 23-04-2016 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 221 239 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 32 53 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 244 261 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 195 212 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 75 94 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00691 Adhesin B signature 139 158 1.8E-8 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 Gene3D G3DSA:3.40.50.1980 29 190 1.3E-46 T 23-04-2016 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00690 Adhesin family signature 32 50 1.2E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00690 Adhesin family signature 62 75 1.2E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00690 Adhesin family signature 195 216 1.2E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00690 Adhesin family signature 248 266 1.2E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 PRINTS PR00690 Adhesin family signature 75 92 1.2E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 Pfam PF01297 Zinc-uptake complex component A periplasmic 35 302 7.5E-68 T 23-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPYM18_RS08930 a651529f2a41b4b3c60ef90c4e14c3b8 306 Gene3D G3DSA:3.40.50.1980 191 306 4.3E-39 T 23-04-2016 SPYM18_RS00900 e314c73898401900b85c94c89b837c33 451 Gene3D G3DSA:2.60.120.260 57 191 2.3E-5 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS00900 e314c73898401900b85c94c89b837c33 451 Pfam PF07461 Nicotine adenine dinucleotide glycohydrolase (NADase) 1 446 0.0 T 23-04-2016 IPR010900 Nicotine adenine dinucleotide glycohydrolase SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Pfam PF02464 Competence-damaged protein 263 416 1.1E-46 T 23-04-2016 IPR008136 CinA, C-terminal SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 PANTHER PTHR13939:SF0 1 422 1.2E-165 T 23-04-2016 SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Pfam PF00994 Probable molybdopterin binding domain 5 170 3.2E-31 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 273 415 1.1E-33 T 23-04-2016 IPR008136 CinA, C-terminal SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 PIRSF PIRSF006728 1 422 2.8E-140 T 23-04-2016 IPR008135 Competence-induced protein CinA SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 SMART SM00852 4 172 1.5E-37 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Gene3D G3DSA:3.90.950.20 257 418 7.7E-51 T 23-04-2016 IPR008136 CinA, C-terminal SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 423 157.4 T 23-04-2016 IPR008135 Competence-induced protein CinA SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 SUPERFAMILY SSF142433 257 418 8.76E-46 T 23-04-2016 IPR008136 CinA, C-terminal SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Gene3D G3DSA:3.40.980.10 1 86 4.7E-34 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 Gene3D G3DSA:3.40.980.10 131 171 4.7E-34 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 PANTHER PTHR13939 1 422 1.2E-165 T 23-04-2016 SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 416 4.7E-117 T 23-04-2016 IPR008135 Competence-induced protein CinA SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 165 4.6E-26 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS09305 5147b88d8aaabbd3c4677517745008f9 423 SUPERFAMILY SSF53218 1 204 1.31E-37 T 23-04-2016 IPR001453 MoaB/Mog domain SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 PANTHER PTHR11931 1 231 2.9E-140 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 229 7.8E-105 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 Gene3D G3DSA:3.40.50.1240 1 227 1.6E-89 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 129 218 1.5E-4 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 123 5.1E-27 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 SUPERFAMILY SSF53254 1 229 8.08E-71 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 SMART SM00855 3 189 4.5E-23 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS06200 3850d01f936d79b95a32f695f90e4d63 231 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 42.954 T 23-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 Gene3D G3DSA:2.30.30.280 214 281 2.5E-31 T 23-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 Gene3D G3DSA:2.40.30.10 283 371 1.0E-31 T 23-04-2016 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 PANTHER PTHR11933:SF10 1 366 2.5E-206 T 23-04-2016 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 PANTHER PTHR11933 1 366 2.5E-206 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 360 3.7E-134 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 361 40.874 T 23-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 SUPERFAMILY SSF52402 8 244 1.63E-57 T 23-04-2016 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 Pfam PF03054 tRNA methyl transferase 8 360 3.7E-145 T 23-04-2016 SPYM18_RS09505 6f3f9a92b0f56048aeb793e50bea4dd7 373 Gene3D G3DSA:3.40.50.620 4 212 2.1E-103 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PRINTS PR00147 DNA photolyase signature 138 154 8.4E-30 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PRINTS PR00147 DNA photolyase signature 369 383 8.4E-30 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PRINTS PR00147 DNA photolyase signature 330 348 8.4E-30 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PRINTS PR00147 DNA photolyase signature 310 326 8.4E-30 T 23-04-2016 IPR002081 Cryptochrome/DNA photolyase class 1 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 330 349 - T 23-04-2016 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PANTHER PTHR11455 1 469 1.7E-168 T 23-04-2016 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 Gene3D G3DSA:1.25.40.80 147 267 8.2E-32 T 23-04-2016 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 Gene3D G3DSA:1.10.579.10 268 462 1.8E-79 T 23-04-2016 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 Pfam PF03441 FAD binding domain of DNA photolyase 261 460 1.1E-83 T 23-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 Gene3D G3DSA:3.40.50.620 2 146 1.3E-37 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 SUPERFAMILY SSF52425 1 179 6.54E-40 T 23-04-2016 IPR006050 DNA photolyase, N-terminal SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 SUPERFAMILY SSF48173 197 464 1.96E-109 T 23-04-2016 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 PANTHER PTHR11455:SF18 1 469 1.7E-168 T 23-04-2016 SPYM18_RS06555 c4317cb73e5e72f4c2d6e4ad9783091c 469 Pfam PF00875 DNA photolyase 3 157 1.0E-39 T 23-04-2016 IPR006050 DNA photolyase, N-terminal SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 5.0E-85 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 23-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 120 1.3E-41 T 23-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 PANTHER PTHR10025 1 280 7.5E-158 T 23-04-2016 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 23-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 SUPERFAMILY SSF51735 122 279 1.37E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 Gene3D G3DSA:3.40.50.720 139 263 3.2E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 2.4E-71 T 23-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 39.391 T 23-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 Gene3D G3DSA:3.40.192.10 6 138 1.5E-52 T 23-04-2016 SPYM18_RS06545 b42f1520c0cdf3cb47cb3ddef68df796 284 SUPERFAMILY SSF53223 1 121 4.8E-41 T 23-04-2016 SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 Pfam PF04851 Type III restriction enzyme, res subunit 257 420 3.2E-19 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 Gene3D G3DSA:3.40.50.300 520 696 7.1E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 Gene3D G3DSA:3.40.50.300 244 444 1.4E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 Pfam PF00271 Helicase conserved C-terminal domain 568 652 4.9E-9 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 SMART SM00490 548 653 1.1E-7 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 TIGRFAM TIGR00595 priA: primosomal protein N' 281 790 1.5E-201 T 23-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 SUPERFAMILY SSF52540 521 699 2.57E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 793 23.949 T 23-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 SUPERFAMILY SSF52540 252 435 1.09E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 PANTHER PTHR30580 1 794 4.2E-264 T 23-04-2016 SPYM18_RS07080 f2b95c21a5fc4ec5c943b7eca9e31aa2 794 SMART SM00487 254 450 3.0E-24 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 46 156 1.9E-15 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 PANTHER PTHR30614:SF16 37 268 1.0E-71 T 23-04-2016 SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 SUPERFAMILY SSF161098 48 247 1.44E-34 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 Gene3D G3DSA:1.10.3720.10 46 261 9.6E-35 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 261 1.5E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS07200 be37a336e67519a97944782d11c5b340 278 PANTHER PTHR30614 37 268 1.0E-71 T 23-04-2016 SPYM18_RS05730 71ea6a39915b07ebc94115a08bc15ba7 327 PANTHER PTHR23024:SF47 91 320 8.5E-29 T 23-04-2016 SPYM18_RS05730 71ea6a39915b07ebc94115a08bc15ba7 327 Gene3D G3DSA:3.40.50.1820 77 318 4.9E-32 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS05730 71ea6a39915b07ebc94115a08bc15ba7 327 Pfam PF07859 alpha/beta hydrolase fold 102 302 6.2E-22 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SPYM18_RS05730 71ea6a39915b07ebc94115a08bc15ba7 327 PANTHER PTHR23024 91 320 8.5E-29 T 23-04-2016 SPYM18_RS05730 71ea6a39915b07ebc94115a08bc15ba7 327 SUPERFAMILY SSF53474 92 318 2.18E-25 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 Gene3D G3DSA:3.40.50.2300 166 240 5.2E-10 T 23-04-2016 SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 Gene3D G3DSA:3.40.50.2300 31 165 4.6E-51 T 23-04-2016 SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 PANTHER PTHR34296 24 347 1.2E-124 T 23-04-2016 SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 Pfam PF02608 Basic membrane protein 37 347 7.5E-76 T 23-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 SUPERFAMILY SSF53822 46 302 2.77E-18 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS00890 6f44b61c28fd0b567696fccffe1446f7 347 PANTHER PTHR34296:SF2 24 347 1.2E-124 T 23-04-2016 SPYM18_RS07930 b9be26c0035d2d98d5b3b966be21dca1 189 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 56 184 5.0E-16 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS07930 b9be26c0035d2d98d5b3b966be21dca1 189 SMART SM00047 37 189 8.1E-13 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 SUPERFAMILY SSF81606 2 239 1.7E-58 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 Gene3D G3DSA:3.60.40.10 2 239 6.8E-61 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 PANTHER PTHR13832 1 238 8.1E-61 T 23-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 SMART SM00332 1 238 1.1E-12 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 Pfam PF13672 Protein phosphatase 2C 12 204 2.6E-15 T 23-04-2016 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 SMART SM00331 7 240 3.6E-35 T 23-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 SPYM18_RS07065 5d2f5500c5a6353a6a748ae21922f29f 246 PANTHER PTHR13832:SF278 1 238 8.1E-61 T 23-04-2016 SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 Pfam PF00348 Polyprenyl synthetase 25 252 3.3E-50 T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 SUPERFAMILY SSF48576 3 267 2.64E-74 T 23-04-2016 IPR008949 Isoprenoid synthase domain SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 PANTHER PTHR12001:SF23 1 265 4.6E-82 T 23-04-2016 SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 PANTHER PTHR12001 1 265 4.6E-82 T 23-04-2016 IPR017446 Polyprenyl synthetase-related SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 Gene3D G3DSA:1.10.600.10 4 272 3.1E-79 T 23-04-2016 IPR008949 Isoprenoid synthase domain SPYM18_RS06530 33f053e8a294732a9e3a3db9b0c430e0 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 92 - T 23-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 SPYM18_RS07705 200e72c88870d64d4045a4583fc173ed 94 Pfam PF11753 Protein of unknwon function (DUF3310) 24 84 4.9E-19 T 23-04-2016 IPR021739 Protein of unknwon function DUF3310 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 Gene3D G3DSA:3.80.30.10 83 256 9.6E-57 T 23-04-2016 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 Pfam PF13353 4Fe-4S single cluster domain 17 138 3.0E-13 T 23-04-2016 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 SUPERFAMILY SSF102114 27 228 8.37E-23 T 23-04-2016 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 ProSitePatterns PS01087 Radical activating enzymes signature. 18 39 - T 23-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 59 250 9.0E-62 T 23-04-2016 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 PANTHER PTHR30352 1 253 2.3E-105 T 23-04-2016 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 PANTHER PTHR30352:SF4 1 253 2.3E-105 T 23-04-2016 SPYM18_RS09070 cfb0b826a8791cfa3fe95206d67ddee5 257 Pfam PF04055 Radical SAM superfamily 25 189 4.7E-26 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SMART SM00831 9 82 1.3E-29 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF56784 473 725 2.43E-58 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF56784 332 352 2.43E-58 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Gene3D G3DSA:2.70.150.10 25 60 2.0E-40 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Gene3D G3DSA:2.70.150.10 118 233 2.0E-40 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF81665 234 328 5.36E-130 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF81665 671 885 5.36E-130 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF81665 10 123 5.36E-130 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PANTHER PTHR24093:SF268 8 891 0.0 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 528 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 549 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 657 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 621 640 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 6.3E-38 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF81653 123 233 2.75E-29 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 635 1.7E-23 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 SUPERFAMILY SSF81660 341 521 4.25E-47 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Pfam PF00690 Cation transporter/ATPase, N-terminus 11 77 5.7E-23 T 23-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PANTHER PTHR24093 8 891 0.0 T 23-04-2016 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Pfam PF00689 Cation transporting ATPase, C-terminus 706 881 1.3E-45 T 23-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Gene3D G3DSA:1.20.1110.10 590 884 9.7E-119 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Gene3D G3DSA:1.20.1110.10 61 117 9.7E-119 T 23-04-2016 IPR023298 P-type ATPase, transmembrane domain SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 184 3.8E-20 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 587 702 2.1E-34 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 226 363 8.8E-27 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 653 678 1.7E-16 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 593 609 1.7E-16 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 476 494 1.7E-16 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 621 637 1.7E-16 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Gene3D G3DSA:3.40.1110.10 325 524 1.4E-56 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site SPYM18_RS02940 4eabee705c0136bbb32a6433ebaab061 893 Pfam PF00122 E1-E2 ATPase 90 325 3.9E-66 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 23-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 7.7E-35 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 Pfam PF00085 Thioredoxin 4 102 4.7E-29 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 Gene3D G3DSA:3.40.30.10 3 103 1.8E-34 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 PANTHER PTHR10438 1 103 5.4E-35 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 PRINTS PR00421 Thioredoxin family signature 68 79 4.5E-7 T 23-04-2016 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 PRINTS PR00421 Thioredoxin family signature 27 36 4.5E-7 T 23-04-2016 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 PRINTS PR00421 Thioredoxin family signature 19 27 4.5E-7 T 23-04-2016 SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 SUPERFAMILY SSF52833 3 102 6.2E-35 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS08195 1a87a8e02cd0fae7e6a4d091e6b54d0c 104 PIRSF PIRSF000077 1 104 3.9E-38 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 PANTHER PTHR39340 1 325 1.3E-123 T 23-04-2016 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 SUPERFAMILY SSF51569 7 321 4.76E-67 T 23-04-2016 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 Gene3D G3DSA:3.20.20.70 5 324 8.7E-129 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 PANTHER PTHR39340:SF1 1 325 1.3E-123 T 23-04-2016 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 Pfam PF01791 DeoC/LacD family aldolase 20 281 2.4E-78 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 SMART SM01133 20 282 9.5E-30 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 325 200.307 T 23-04-2016 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS07360 f46b6160cee4d1ea6220bb1d5727a722 325 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 4 324 6.0E-166 T 23-04-2016 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 SMART SM00882 15 209 7.7E-55 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 Gene3D G3DSA:3.40.810.20 14 215 2.4E-74 T 23-04-2016 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 PANTHER PTHR13707 16 211 1.2E-91 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 14 215 8.0E-84 T 23-04-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 53 61 - T 23-04-2016 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 SUPERFAMILY SSF100950 13 215 7.91E-59 T 23-04-2016 SPYM18_RS07115 d8179970df178450f91b38b3d3b378b1 219 Pfam PF01144 Coenzyme A transferase 16 206 2.3E-29 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.30.1490.20 132 154 6.6E-29 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.30.1490.20 201 248 6.6E-29 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:1.20.1580.10 249 282 1.4E-49 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:1.20.1580.10 92 130 1.4E-49 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:1.20.1580.10 406 479 1.4E-49 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 925 0.0 T 23-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 SUPERFAMILY SSF52540 11 205 1.43E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 SUPERFAMILY SSF52540 432 571 1.43E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 SMART SM00382 633 908 5.4E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:1.10.8.280 284 405 1.6E-43 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 PANTHER PTHR32282:SF2 1 942 0.0 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Pfam PF00005 ABC transporter 624 860 1.2E-9 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.40.50.300 480 597 2.1E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.40.50.300 612 669 4.5E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.40.50.300 7 90 2.1E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:3.40.50.300 821 939 4.5E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.692 T 23-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 Gene3D G3DSA:1.20.1580.10 694 820 6.8E-56 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 PANTHER PTHR32282 1 942 0.0 T 23-04-2016 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08150 fcfaa6d8dfc67a71f8c6651b9019043e 942 SUPERFAMILY SSF52540 615 913 2.34E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03680 249039a3d5feacc7f43979e4fcc7d74e 824 Pfam PF00884 Sulfatase 480 764 3.7E-39 T 23-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SPYM18_RS03680 249039a3d5feacc7f43979e4fcc7d74e 824 Gene3D G3DSA:3.40.720.10 555 723 5.1E-6 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPYM18_RS05535 318c0535aabe6e44724b887e7d58367b 160 PANTHER PTHR41328 11 147 1.8E-16 T 23-04-2016 SPYM18_RS05535 318c0535aabe6e44724b887e7d58367b 160 Pfam PF03592 Terminase small subunit 13 146 2.2E-28 T 23-04-2016 IPR005335 Terminase small subunit GO:0006323 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 Pfam PF00117 Glutamine amidotransferase class-I 3 183 6.5E-49 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 SUPERFAMILY SSF52317 1 186 2.22E-50 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 8.4E-14 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 8.4E-14 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 72 83 8.4E-14 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 97 105 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 72 83 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 162 175 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 118 130 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00097 Anthranilate synthase component II signature 45 54 2.4E-33 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PANTHER PTHR11922:SF7 1 183 9.5E-65 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 184 1.6E-51 T 23-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PANTHER PTHR11922 1 183 9.5E-65 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 72 88 2.8E-7 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 2.8E-7 T 23-04-2016 SPYM18_RS08860 5129143d9e250f5ad86d0bef8701b9bd 188 Gene3D G3DSA:3.40.50.880 1 184 1.7E-59 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 130 147 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 Gene3D G3DSA:3.20.20.100 2 266 1.9E-104 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PIRSF PIRSF000097 1 278 2.5E-84 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 234 249 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 Pfam PF00248 Aldo/keto reductase family 16 263 4.2E-49 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PANTHER PTHR11732 1 263 5.8E-134 T 23-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 SUPERFAMILY SSF51430 1 265 2.75E-92 T 23-04-2016 IPR023210 NADP-dependent oxidoreductase domain SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PRINTS PR00069 Aldo-keto reductase signature 36 60 2.3E-48 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PRINTS PR00069 Aldo-keto reductase signature 130 147 2.3E-48 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PRINTS PR00069 Aldo-keto reductase signature 201 225 2.3E-48 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PRINTS PR00069 Aldo-keto reductase signature 92 110 2.3E-48 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 PRINTS PR00069 Aldo-keto reductase signature 164 193 2.3E-48 T 23-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 SPYM18_RS07320 2e63a50ac122fcb185b3495e9f6ee4ec 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 40 57 - T 23-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 SUPERFAMILY SSF81301 1 114 4.74E-39 T 23-04-2016 SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 PANTHER PTHR21043 1 108 1.4E-38 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 Gene3D G3DSA:3.30.460.10 2 107 6.6E-39 T 23-04-2016 SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 1.3E-27 T 23-04-2016 SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 25.562 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SPYM18_RS01425 1315179cad149fa86adf2c05ea714e2a 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 5.8E-36 T 23-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 Gene3D G3DSA:1.10.10.10 135 233 3.5E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 SMART SM00448 2 112 5.2E-47 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 PANTHER PTHR26402:SF614 2 233 2.7E-105 T 23-04-2016 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 PANTHER PTHR26402 2 233 2.7E-105 T 23-04-2016 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 1.6E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 Gene3D G3DSA:3.40.50.2300 1 123 1.7E-42 T 23-04-2016 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 SUPERFAMILY SSF52172 1 125 9.39E-43 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 SMART SM00862 156 232 1.9E-27 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 Pfam PF00072 Response regulator receiver domain 4 113 7.8E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS02570 908aa5bb8597c5f790005887083d0b6c 236 SUPERFAMILY SSF46894 132 232 1.87E-30 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPYM18_RS08315 b9aa0ec07070baf5c5b996a84dceff53 176 Gene3D G3DSA:1.10.10.10 5 33 5.0E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08315 b9aa0ec07070baf5c5b996a84dceff53 176 Pfam PF04394 Protein of unknown function, DUF536 104 146 1.5E-18 T 23-04-2016 IPR007489 Domain of unknown function DUF536 SPYM18_RS08315 b9aa0ec07070baf5c5b996a84dceff53 176 Pfam PF08279 HTH domain 6 33 5.2E-5 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS06845 d3cbedaa3572460aa1ad5ede7e8482e2 101 Pfam PF07883 Cupin domain 33 96 2.2E-7 T 23-04-2016 IPR013096 Cupin 2, conserved barrel SPYM18_RS06845 d3cbedaa3572460aa1ad5ede7e8482e2 101 SUPERFAMILY SSF51182 3 96 1.21E-12 T 23-04-2016 IPR011051 RmlC-like cupin domain SPYM18_RS06845 d3cbedaa3572460aa1ad5ede7e8482e2 101 Gene3D G3DSA:2.60.120.10 2 99 5.3E-23 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 82 5.4E-9 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 PANTHER PTHR11751 28 108 6.1E-18 T 23-04-2016 SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 PANTHER PTHR11751:SF384 28 108 6.1E-18 T 23-04-2016 SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 SMART SM00345 24 82 2.3E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 Pfam PF07729 FCD domain 92 215 3.3E-19 T 23-04-2016 IPR011711 GntR, C-terminal SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 Gene3D G3DSA:1.10.10.10 7 83 1.2E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 SUPERFAMILY SSF48008 88 223 3.4E-19 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 SMART SM00895 92 216 2.2E-8 T 23-04-2016 IPR011711 GntR, C-terminal SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 Gene3D G3DSA:1.20.120.530 86 227 1.2E-30 T 23-04-2016 IPR008920 Transcription regulator FadR/GntR, C-terminal SPYM18_RS04895 84ad73ba8fe61e5f282c381c1e258c01 231 SUPERFAMILY SSF46785 13 86 5.54E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SMART SM00062 270 491 1.0E-51 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SMART SM00062 26 248 1.8E-49 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 246 2.5E-55 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 272 489 1.3E-55 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SUPERFAMILY SSF53850 271 488 9.51E-60 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 514 618 4.6E-22 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 PANTHER PTHR30614:SF0 269 723 7.2E-237 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:1.10.3720.10 503 723 7.2E-70 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SUPERFAMILY SSF53850 7 248 1.71E-58 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 536 723 4.8E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SUPERFAMILY SSF161098 516 709 3.4E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 357 442 3.5E-24 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 113 205 1.1E-25 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 SMART SM00079 27 247 7.3E-5 T 23-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 PANTHER PTHR30614 269 723 7.2E-237 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 449 490 2.2E-38 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 270 356 2.2E-38 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 24 112 3.7E-35 T 23-04-2016 SPYM18_RS05765 adb4eafe7313b57ee86da7e87b9a3ee8 724 Gene3D G3DSA:3.40.190.10 206 248 3.7E-35 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 SMART SM00062 38 266 9.0E-45 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 263 8.7E-52 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 PANTHER PTHR18966:SF208 34 267 2.2E-33 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 Gene3D G3DSA:3.40.190.10 123 225 3.8E-41 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 PANTHER PTHR18966 34 267 2.2E-33 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 23-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 Gene3D G3DSA:3.40.190.10 34 122 2.3E-36 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 Gene3D G3DSA:3.40.190.10 226 264 2.3E-36 T 23-04-2016 SPYM18_RS04145 3744f7c136eb25e544ed91545015a824 287 SUPERFAMILY SSF53850 1 263 5.27E-56 T 23-04-2016 SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 Pfam PF00270 DEAD/DEAH box helicase 26 190 2.6E-50 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 Gene3D G3DSA:3.40.50.300 208 369 8.8E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 23-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 SMART SM00487 20 217 2.3E-63 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 PANTHER PTHR24031 2 515 1.3E-231 T 23-04-2016 SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 SMART SM00490 253 334 1.3E-33 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 PANTHER PTHR24031:SF261 2 515 1.3E-231 T 23-04-2016 SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 Gene3D G3DSA:3.40.50.300 2 207 1.6E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 Pfam PF00271 Helicase conserved C-terminal domain 226 334 1.2E-28 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 535 43.943 T 23-04-2016 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 SPYM18_RS06155 0c29ae96a6e6a781de645db4a782da89 539 SUPERFAMILY SSF52540 71 355 6.77E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 SUPERFAMILY SSF51161 256 446 1.48E-45 T 23-04-2016 IPR011004 Trimeric LpxA-like SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 SUPERFAMILY SSF53448 4 252 1.34E-62 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 451 8.7E-173 T 23-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Pfam PF12804 MobA-like NTP transferase domain 5 130 1.4E-18 T 23-04-2016 IPR025877 MobA-like NTP transferase SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 PANTHER PTHR22572 4 448 1.2E-208 T 23-04-2016 SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 350 1.9E-4 T 23-04-2016 IPR001451 Hexapeptide repeat SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 40.951 T 23-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 PANTHER PTHR22572:SF115 4 448 1.2E-208 T 23-04-2016 SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Gene3D G3DSA:3.90.550.10 1 244 4.4E-77 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 394 428 1.8E-6 T 23-04-2016 IPR001451 Hexapeptide repeat SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Gene3D G3DSA:2.160.10.10 334 451 3.6E-35 T 23-04-2016 SPYM18_RS02140 4aa1eb3e34a2ca3a613aca5d1e87ebf2 460 Gene3D G3DSA:2.160.10.10 245 333 6.9E-18 T 23-04-2016 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 SMART SM00937 65 180 1.3E-60 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 358 39.156 T 23-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 PANTHER PTHR11075 2 357 6.5E-166 T 23-04-2016 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 SUPERFAMILY SSF75620 10 354 1.18E-126 T 23-04-2016 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 357 1.9E-157 T 23-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 Pfam PF00472 RF-1 domain 213 322 3.4E-37 T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 PANTHER PTHR11075:SF9 2 357 6.5E-166 T 23-04-2016 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 Pfam PF03462 PCRF domain 11 205 1.8E-71 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 Gene3D G3DSA:1.20.58.410 4 95 2.9E-22 T 23-04-2016 SPYM18_RS04755 5252989b79e8e703d645b6c14c661273 359 Gene3D G3DSA:3.30.160.20 212 285 5.4E-29 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 Gene3D G3DSA:1.10.3720.10 101 302 2.5E-17 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 PANTHER PTHR30465 21 308 4.4E-134 T 23-04-2016 SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 SUPERFAMILY SSF161098 102 287 7.33E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 305 3.7E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 PANTHER PTHR30465:SF75 21 308 4.4E-134 T 23-04-2016 SPYM18_RS01350 17cadb8b441ae7d95a8e233a909d07ef 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 72 2.4E-9 T 23-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain SPYM18_RS06685 e3743d58684a34234aa699ae2b8bd719 206 PANTHER PTHR41319:SF1 2 173 1.0E-42 T 23-04-2016 SPYM18_RS06685 e3743d58684a34234aa699ae2b8bd719 206 PANTHER PTHR41319 2 173 1.0E-42 T 23-04-2016 SPYM18_RS06685 e3743d58684a34234aa699ae2b8bd719 206 Pfam PF06265 Protein of unknown function (DUF1027) 32 111 1.6E-33 T 23-04-2016 IPR009370 Protein of unknown function DUF1027 SPYM18_RS06685 e3743d58684a34234aa699ae2b8bd719 206 PIRSF PIRSF012565 1 206 2.6E-72 T 23-04-2016 IPR009370 Protein of unknown function DUF1027 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 1.5E-27 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 171 6.7E-62 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 23-04-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 8.7E-35 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 SUPERFAMILY SSF54364 9 82 1.07E-26 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 Gene3D G3DSA:3.30.110.10 83 175 3.0E-35 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 PANTHER PTHR10938 4 176 9.4E-62 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 174 29.23 T 23-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 SUPERFAMILY SSF55200 86 175 5.23E-31 T 23-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 SPYM18_RS03725 85aad72d55af0860c17eac3dad53644c 176 Gene3D G3DSA:3.10.20.80 6 82 4.4E-32 T 23-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 SPYM18_RS02435 674cf983cb7ff7b17dea7903fdb9a486 236 SUPERFAMILY SSF50969 21 192 5.02E-11 T 23-04-2016 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like SPYM18_RS02435 674cf983cb7ff7b17dea7903fdb9a486 236 PANTHER PTHR31270:SF0 7 235 1.7E-55 T 23-04-2016 SPYM18_RS02435 674cf983cb7ff7b17dea7903fdb9a486 236 Gene3D G3DSA:2.130.10.10 44 188 1.4E-4 T 23-04-2016 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 SPYM18_RS02435 674cf983cb7ff7b17dea7903fdb9a486 236 Pfam PF05096 Glutamine cyclotransferase 5 233 1.3E-60 T 23-04-2016 IPR007788 Glutamine cyclotransferase SPYM18_RS02435 674cf983cb7ff7b17dea7903fdb9a486 236 PANTHER PTHR31270 7 235 1.7E-55 T 23-04-2016 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 SMART SM01185 67 121 1.6E-18 T 23-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 PIRSF PIRSF005901 1 185 5.3E-63 T 23-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 47.38 T 23-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 1.7E-67 T 23-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 SUPERFAMILY SSF50249 64 126 1.2E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 SUPERFAMILY SSF50249 128 185 1.16E-16 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 PANTHER PTHR30053 1 185 2.2E-78 T 23-04-2016 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 3.9E-24 T 23-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 69 121 1.6E-15 T 23-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Gene3D G3DSA:2.40.50.140 65 127 3.6E-20 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 SMART SM00841 129 184 1.9E-30 T 23-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Gene3D G3DSA:2.40.50.140 128 185 3.5E-25 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 23-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 SUPERFAMILY SSF50104 1 63 4.27E-19 T 23-04-2016 IPR008991 Translation protein SH3-like domain SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Gene3D G3DSA:2.30.30.30 1 63 4.0E-24 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 SPYM18_RS08135 ee46a856b8331859e6096d18cfc8e683 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 2.6E-23 T 23-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 Gene3D G3DSA:3.40.1400.10 1 141 2.8E-43 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 PIRSF PIRSF005384 1 142 5.4E-42 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 PANTHER PTHR30345:SF5 1 142 3.1E-87 T 23-04-2016 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 PANTHER PTHR30345 1 142 3.1E-87 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 TIGRFAM TIGR01118 lacA: galactose-6-phosphate isomerase, LacA subunit 1 141 8.0E-76 T 23-04-2016 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 Pfam PF02502 Ribose/Galactose Isomerase 3 138 1.7E-39 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 SUPERFAMILY SSF89623 1 141 1.57E-45 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 Hamap MF_01555 Galactose-6-phosphate isomerase subunit LacA [lacA]. 1 142 40.28 T 23-04-2016 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08595 4f8d7a74fbc8655f0cd48bfd5e415460 142 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 140 7.3E-36 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 257 1.1E-122 T 23-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 PANTHER PTHR40062 2 260 1.9E-118 T 23-04-2016 SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 Pfam PF08222 CodY helix-turn-helix domain 202 260 1.2E-37 T 23-04-2016 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 PIRSF PIRSF011572 1 260 3.8E-120 T 23-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 SUPERFAMILY SSF46785 171 259 1.6E-40 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 Gene3D G3DSA:1.10.10.10 167 237 5.1E-8 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 Pfam PF06018 CodY GAF-like domain 3 182 1.6E-74 T 23-04-2016 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 SPYM18_RS07980 67e219c508c53297e49d258dc93d21b2 260 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 260 128.742 T 23-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 SUPERFAMILY SSF52096 28 173 9.05E-39 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 PRINTS PR00127 Clp protease catalytic subunit P signature 150 169 5.2E-11 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 PRINTS PR00127 Clp protease catalytic subunit P signature 74 91 5.2E-11 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 PRINTS PR00127 Clp protease catalytic subunit P signature 43 63 5.2E-11 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 Pfam PF00574 Clp protease 40 173 1.7E-28 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 PANTHER PTHR10381:SF23 35 197 3.4E-28 T 23-04-2016 SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 PANTHER PTHR10381 35 197 3.4E-28 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS01710 83555eba77cc74c0c58de5262f2228fd 268 Gene3D G3DSA:3.90.226.10 34 175 9.9E-39 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 PANTHER PTHR30006 1 311 1.5E-42 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 SUPERFAMILY SSF53850 36 339 8.54E-58 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 PANTHER PTHR30006:SF6 1 311 1.5E-42 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 Gene3D G3DSA:3.40.190.10 138 274 3.0E-29 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 PIRSF PIRSF002825 6 340 5.6E-52 T 23-04-2016 IPR026045 Ferric binding protein SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 Gene3D G3DSA:3.40.190.10 10 132 9.1E-24 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 Gene3D G3DSA:3.40.190.10 275 330 9.1E-24 T 23-04-2016 SPYM18_RS04495 a7bba88c8c4d7369e0d5dbc66d8e3bec 348 Pfam PF13343 Bacterial extracellular solute-binding protein 89 306 8.5E-29 T 23-04-2016 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 SUPERFAMILY SSF69189 285 402 9.42E-13 T 23-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 Gene3D G3DSA:2.60.410.10 296 391 3.3E-22 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 Gene3D G3DSA:3.40.710.10 23 290 8.9E-78 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 111 128 3.3E-12 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 55 66 3.3E-12 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 138 151 3.3E-12 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 20 269 4.0E-93 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 PANTHER PTHR21581:SF11 1 365 1.2E-86 T 23-04-2016 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 PANTHER PTHR21581 1 365 1.2E-86 T 23-04-2016 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 SUPERFAMILY SSF56601 5 290 8.31E-61 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 293 390 1.2E-15 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS01335 a177fda10bd4404deb2eaca3dec8daab 410 SMART SM00936 293 391 2.6E-14 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 PANTHER PTHR11061 19 387 1.2E-111 T 23-04-2016 SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 158 338 7.8E-29 T 23-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 SUPERFAMILY SSF88697 1 67 2.73E-18 T 23-04-2016 IPR015947 PUA-like domain SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 Gene3D G3DSA:3.40.50.150 111 386 4.4E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 PANTHER PTHR11061:SF15 19 387 1.2E-111 T 23-04-2016 SPYM18_RS03745 5d0d0d3a63e57b19bcaad41f7312b67d 387 SUPERFAMILY SSF53335 75 379 8.36E-61 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS00950 6b44d8a7b7735b87608ab42ec7cba17f 161 PANTHER PTHR36203 1 153 2.6E-35 T 23-04-2016 SPYM18_RS00950 6b44d8a7b7735b87608ab42ec7cba17f 161 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 1.2E-32 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS00950 6b44d8a7b7735b87608ab42ec7cba17f 161 SUPERFAMILY SSF55804 6 147 3.49E-31 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 SPYM18_RS00950 6b44d8a7b7735b87608ab42ec7cba17f 161 Gene3D G3DSA:3.40.930.10 6 153 7.3E-50 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 PIRSF PIRSF029928 1 108 1.8E-39 T 23-04-2016 IPR016940 ComG operon protein C GO:0030420 SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 34 5.5E-6 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 SUPERFAMILY SSF54523 16 101 1.73E-13 T 23-04-2016 SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 14 34 - T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 Pfam PF07963 Prokaryotic N-terminal methylation motif 14 33 8.7E-6 T 23-04-2016 IPR012902 Prokaryotic N-terminal methylation site SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 3.1E-9 T 23-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SPYM18_RS00655 efe179dd5a9a0b63035ce701cbd50d9b 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 3.1E-9 T 23-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Gene3D G3DSA:3.40.1390.20 67 187 3.8E-42 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 PANTHER PTHR11911 188 299 5.4E-21 T 23-04-2016 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Gene3D G3DSA:3.10.580.10 188 307 3.9E-28 T 23-04-2016 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Pfam PF07085 DRTGG domain 75 177 4.8E-30 T 23-04-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Pfam PF03061 Thioesterase superfamily 344 416 1.3E-4 T 23-04-2016 IPR006683 Thioesterase domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SUPERFAMILY SSF46785 3 62 2.27E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SUPERFAMILY SSF54631 184 304 2.32E-26 T 23-04-2016 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SUPERFAMILY SSF54637 325 423 1.72E-11 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Gene3D G3DSA:3.10.129.10 329 420 4.4E-7 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Gene3D G3DSA:1.10.10.10 13 58 2.0E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 58 4.0E-5 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SMART SM00116 258 306 8.0E-5 T 23-04-2016 IPR000644 CBS domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SMART SM00116 199 247 0.06 T 23-04-2016 IPR000644 CBS domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Pfam PF00571 CBS domain 253 304 1.2E-8 T 23-04-2016 IPR000644 CBS domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 Pfam PF00571 CBS domain 191 245 2.2E-6 T 23-04-2016 IPR000644 CBS domain SPYM18_RS05915 b2c5ef625804a73cb925d5164fd32c8d 427 SUPERFAMILY SSF75138 71 183 1.23E-28 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 SUPERFAMILY SSF52540 3 239 1.66E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 PANTHER PTHR24220 7 249 1.2E-124 T 23-04-2016 SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 PANTHER PTHR24220:SF585 7 249 1.2E-124 T 23-04-2016 SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 7.0E-118 T 23-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 Pfam PF00005 ABC transporter 21 177 4.4E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 SMART SM00382 30 223 6.7E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05150 6525ba83ebaef6b3d274b34eac96e0fa 252 Gene3D G3DSA:3.40.50.300 4 247 4.9E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 SUPERFAMILY SSF52413 310 402 9.42E-25 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 PIRSF PIRSF000124 1 402 4.5E-148 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 167 1.9E-29 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 PANTHER PTHR11374:SF17 1 385 1.2E-186 T 23-04-2016 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 SMART SM00984 313 401 9.9E-13 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 199 288 1.3E-23 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Gene3D G3DSA:3.40.50.720 292 402 1.0E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 PANTHER PTHR11374 1 385 1.2E-186 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 SUPERFAMILY SSF51735 1 201 3.75E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 SUPERFAMILY SSF48179 199 294 1.07E-28 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Gene3D G3DSA:1.10.1040.10 205 291 9.0E-32 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 390 5.5E-11 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 Gene3D G3DSA:3.40.50.720 1 204 1.8E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 392 2.0E-92 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS09565 20b7705f9088b206e522122245ebfd5c 402 PIRSF PIRSF500134 1 396 3.3E-110 T 23-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 PANTHER PTHR21085:SF0 1 388 5.8E-169 T 23-04-2016 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 Gene3D G3DSA:3.60.150.10 1 387 3.5E-140 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 33.575 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 PANTHER PTHR21085 1 388 5.8E-169 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 SUPERFAMILY SSF103263 1 387 4.06E-141 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 PIRSF PIRSF001456 1 380 1.4E-117 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 23-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 Pfam PF01264 Chorismate synthase 1 363 1.1E-111 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS03755 b9f47d94b49b88efc1e1c976f246e74e 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.2E-128 T 23-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS02015 03c9ff16b9f6fe293eb8280932943309 91 PANTHER PTHR41304:SF1 3 91 6.7E-15 T 23-04-2016 SPYM18_RS02015 03c9ff16b9f6fe293eb8280932943309 91 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 7 76 1.4E-25 T 23-04-2016 IPR016979 Protein of unknown function DUF2129 SPYM18_RS02015 03c9ff16b9f6fe293eb8280932943309 91 PANTHER PTHR41304 3 91 6.7E-15 T 23-04-2016 SPYM18_RS02015 03c9ff16b9f6fe293eb8280932943309 91 PIRSF PIRSF031653 1 91 1.1E-30 T 23-04-2016 IPR016979 Protein of unknown function DUF2129 SPYM18_RS02015 03c9ff16b9f6fe293eb8280932943309 91 Hamap MF_01126 UPF0298 protein . 3 80 21.364 T 23-04-2016 IPR016979 Protein of unknown function DUF2129 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 SMART SM00480 18 373 1.1E-137 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 SUPERFAMILY SSF55979 133 251 7.85E-22 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 3 126 5.5E-25 T 23-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Gene3D G3DSA:3.10.150.10 258 378 3.1E-32 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 1.7E-27 T 23-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 375 7.3E-26 T 23-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 SUPERFAMILY SSF55979 3 129 2.9E-18 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 PANTHER PTHR30478 3 378 2.0E-107 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 3 377 1.2E-84 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Gene3D G3DSA:3.10.150.10 3 129 3.6E-22 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 SUPERFAMILY SSF55979 253 377 3.53E-28 T 23-04-2016 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 PIRSF PIRSF000804 2 378 1.5E-93 T 23-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00010 fcc43d0bdc7262e4346a340cb22969d5 378 Gene3D G3DSA:3.10.150.10 134 254 3.7E-29 T 23-04-2016 SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 Gene3D G3DSA:3.40.350.10 3 131 4.5E-26 T 23-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 Pfam PF00557 Metallopeptidase family M24 141 343 9.0E-60 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 Gene3D G3DSA:3.90.230.10 133 356 2.5E-81 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 289 301 - T 23-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 SUPERFAMILY SSF53092 2 131 2.62E-25 T 23-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 PANTHER PTHR10804:SF106 1 360 9.4E-176 T 23-04-2016 SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 PANTHER PTHR10804 1 360 9.4E-176 T 23-04-2016 SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 133 4.6E-16 T 23-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 SPYM18_RS02470 4b7faf87c6d6410baad08ed076b7d17d 361 SUPERFAMILY SSF55920 89 354 4.58E-78 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS03090 d5b6333bbf33e8931161466003acfe8f 253 SMART SM01040 11 98 2.9E-45 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS03090 d5b6333bbf33e8931161466003acfe8f 253 PANTHER PTHR36180:SF2 5 110 1.5E-40 T 23-04-2016 SPYM18_RS03090 d5b6333bbf33e8931161466003acfe8f 253 PANTHER PTHR36180 5 110 1.5E-40 T 23-04-2016 SPYM18_RS03090 d5b6333bbf33e8931161466003acfe8f 253 Pfam PF03374 Phage antirepressor protein KilAC domain 136 246 1.1E-33 T 23-04-2016 IPR005039 Antirepressor protein, C-terminal GO:0003677 SPYM18_RS03090 d5b6333bbf33e8931161466003acfe8f 253 Pfam PF02498 BRO family, N-terminal domain 11 98 5.9E-32 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.359 T 23-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 SUPERFAMILY SSF54211 5 130 2.84E-48 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 Gene3D G3DSA:3.30.230.10 5 130 2.0E-51 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 PANTHER PTHR21569 1 130 6.6E-69 T 23-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 23-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08620 46713cc5113a9673a5ed4368ee53ee36 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 5.9E-49 T 23-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS07485 8aeb9e8ad258da0c269f9c2280456ec6 427 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 80 237 1.7E-44 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain SPYM18_RS07485 8aeb9e8ad258da0c269f9c2280456ec6 427 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 81 237 2.2E-49 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain SPYM18_RS07485 8aeb9e8ad258da0c269f9c2280456ec6 427 PANTHER PTHR33392 1 338 2.9E-111 T 23-04-2016 SPYM18_RS07485 8aeb9e8ad258da0c269f9c2280456ec6 427 PANTHER PTHR33392:SF5 1 338 2.9E-111 T 23-04-2016 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Gene3D G3DSA:1.10.1780.10 4 154 8.1E-18 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Gene3D G3DSA:1.10.8.60 377 453 1.8E-24 T 23-04-2016 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PANTHER PTHR11638:SF18 4 813 0.0 T 23-04-2016 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SMART SM01086 722 811 2.5E-30 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PANTHER PTHR11638 4 813 0.0 T 23-04-2016 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 579 597 - T 23-04-2016 IPR028299 ClpA/B, conserved site 2 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Gene3D G3DSA:1.10.8.60 732 812 2.6E-26 T 23-04-2016 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SUPERFAMILY SSF81923 4 127 2.49E-13 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 327 339 - T 23-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 236 368 1.2E-11 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SMART SM00382 231 376 5.0E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SMART SM00382 545 685 2.1E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 722 801 3.7E-22 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Gene3D G3DSA:3.40.50.300 194 374 2.2E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SUPERFAMILY SSF52540 494 803 3.65E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 623 641 3.27E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 549 567 3.27E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 656 670 3.27E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 594 612 3.27E-41 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Gene3D G3DSA:3.40.50.300 498 731 1.1E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Pfam PF07724 AAA domain (Cdc48 subfamily) 544 715 3.7E-52 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 SUPERFAMILY SSF52540 194 446 6.4E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09130 9059fd3d268e6ee990fde14ae990b17b 814 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 131 7.0E-4 T 23-04-2016 IPR004176 Clp, N-terminal GO:0019538 SPYM18_RS05380 dd4d1dca483c9c2f0ee01b0b1129759f 213 Pfam PF05257 CHAP domain 1 81 2.8E-9 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS05380 dd4d1dca483c9c2f0ee01b0b1129759f 213 Pfam PF08460 Bacterial SH3 domain 134 196 2.4E-8 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type SPYM18_RS05380 dd4d1dca483c9c2f0ee01b0b1129759f 213 SUPERFAMILY SSF54001 1 115 1.86E-10 T 23-04-2016 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 SUPERFAMILY SSF64288 66 242 2.86E-7 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 8.1E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 8.1E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 1.2E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 PANTHER PTHR11751 17 79 4.9E-18 T 23-04-2016 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 PANTHER PTHR11751 164 182 4.9E-18 T 23-04-2016 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 SUPERFAMILY SSF46785 14 81 5.21E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 SMART SM00345 18 77 5.9E-18 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 Gene3D G3DSA:1.10.10.10 11 74 3.5E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08340 5059d2f70fda477434fa0ab87043821b 252 Gene3D G3DSA:3.40.1410.10 75 243 8.1E-8 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 PANTHER PTHR17224:SF1 3 188 9.6E-72 T 23-04-2016 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 Gene3D G3DSA:3.40.50.1470 1 188 6.0E-70 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 187 2.8E-57 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 PANTHER PTHR17224 3 188 9.6E-72 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 23-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 23-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 37.154 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 188 8.0E-64 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS00025 02726295961af8902a770763ce5c0695 189 SUPERFAMILY SSF53178 1 188 1.29E-66 T 23-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 PANTHER PTHR33449:SF1 1 99 1.3E-33 T 23-04-2016 SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 PANTHER PTHR33449 1 99 1.3E-33 T 23-04-2016 SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 90 4.6E-23 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 4.9E-27 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 PIRSF PIRSF004555 1 99 2.8E-28 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 SUPERFAMILY SSF82607 4 94 1.44E-27 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 Gene3D G3DSA:3.30.1310.10 1 97 2.5E-29 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS08300 06f282d96c6b1e4981b7f508ff088f67 99 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 20.252 T 23-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family SPYM18_RS01490 711cc8287223bd42dcd8553ff329d1c6 185 SUPERFAMILY SSF140478 25 172 7.72E-56 T 23-04-2016 IPR023353 LemA-like domain SPYM18_RS01490 711cc8287223bd42dcd8553ff329d1c6 185 PANTHER PTHR34478:SF2 1 184 2.7E-84 T 23-04-2016 SPYM18_RS01490 711cc8287223bd42dcd8553ff329d1c6 185 PANTHER PTHR34478 1 184 2.7E-84 T 23-04-2016 SPYM18_RS01490 711cc8287223bd42dcd8553ff329d1c6 185 Gene3D G3DSA:1.20.1440.20 13 183 1.7E-65 T 23-04-2016 IPR023353 LemA-like domain SPYM18_RS01490 711cc8287223bd42dcd8553ff329d1c6 185 Pfam PF04011 LemA family 6 183 7.8E-70 T 23-04-2016 IPR007156 LemA SPYM18_RS06100 566c61d76ae910215da57092f7f30f1b 406 Pfam PF11311 Protein of unknown function (DUF3114) 110 367 3.0E-92 T 23-04-2016 IPR021462 Protein of unknown function DUF3114 SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 Gene3D G3DSA:3.40.50.720 1 223 1.9E-54 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PANTHER PTHR24322:SF509 147 179 2.2E-62 T 23-04-2016 SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PANTHER PTHR24322:SF509 8 131 2.2E-62 T 23-04-2016 SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 Pfam PF00106 short chain dehydrogenase 5 187 3.0E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 SUPERFAMILY SSF51735 2 250 1.31E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 3.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 3.1E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 5.9E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.9E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 5.9E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 5.9E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 5.9E-27 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PANTHER PTHR24322 147 179 2.2E-62 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04250 f2ff25525f4944a48387e802ea77b53f 254 PANTHER PTHR24322 8 131 2.2E-62 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 218 8.4E-76 T 23-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 Gene3D G3DSA:3.40.50.300 4 220 1.7E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 Pfam PF02224 Cytidylate kinase 6 220 3.5E-74 T 23-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 SUPERFAMILY SSF52540 1 220 2.5E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 PANTHER PTHR21299 6 225 1.0E-69 T 23-04-2016 SPYM18_RS03720 9559a5bb16e480ca178c64a1cd6d04b8 226 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 33.699 T 23-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 Gene3D G3DSA:3.20.20.120 128 432 5.6E-136 T 23-04-2016 IPR029065 Enolase C-terminal domain-like SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 SUPERFAMILY SSF51604 139 433 3.25E-126 T 23-04-2016 IPR029065 Enolase C-terminal domain-like SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 432 1.1E-206 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 SMART SM01193 4 134 7.6E-96 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 Pfam PF03952 Enolase, N-terminal domain 4 134 4.2E-61 T 23-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 Hamap MF_00318 Enolase [eno]. 2 418 44.755 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 SMART SM01192 139 432 5.0E-212 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PANTHER PTHR11902 1 432 8.7E-262 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 SUPERFAMILY SSF54826 3 138 1.33E-58 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 Gene3D G3DSA:3.30.390.10 4 125 4.4E-57 T 23-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 ProSitePatterns PS00164 Enolase signature. 341 354 - T 23-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PIRSF PIRSF001400 1 432 1.1E-189 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 430 5.7E-129 T 23-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 341 355 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 370 387 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 161 174 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 107 123 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 37 51 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS03440 ec8bc709af26dd119463db2ac7a7013b 435 PRINTS PR00148 Enolase signature 318 329 2.3E-46 T 23-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 SMART SM00849 496 702 1.7E-10 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 Gene3D G3DSA:3.60.15.10 485 737 1.8E-35 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 SUPERFAMILY SSF56281 488 735 1.4E-49 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 Pfam PF03772 Competence protein 217 462 1.3E-29 T 23-04-2016 IPR004477 ComEC/Rec2-related protein SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 Pfam PF00753 Metallo-beta-lactamase superfamily 495 701 5.3E-10 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 PANTHER PTHR30619:SF2 3 736 4.2E-141 T 23-04-2016 SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 Pfam PF13567 Domain of unknown function (DUF4131) 24 179 1.4E-6 T 23-04-2016 IPR025405 Domain of unknown function DUF4131 SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 PANTHER PTHR30619 3 736 4.2E-141 T 23-04-2016 SPYM18_RS06125 89ea675a5e8446017837262903951e53 747 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 109 731 2.2E-82 T 23-04-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 SPYM18_RS08700 ca8202bdf72d3cfb081b4be2479bf022 94 PANTHER PTHR33843 1 90 7.5E-22 T 23-04-2016 SPYM18_RS08700 ca8202bdf72d3cfb081b4be2479bf022 94 PANTHER PTHR33843:SF2 1 90 7.5E-22 T 23-04-2016 SPYM18_RS08700 ca8202bdf72d3cfb081b4be2479bf022 94 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 81 7.5E-14 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS08700 ca8202bdf72d3cfb081b4be2479bf022 94 Gene3D G3DSA:3.40.50.270 1 81 1.7E-12 T 23-04-2016 SPYM18_RS08700 ca8202bdf72d3cfb081b4be2479bf022 94 SUPERFAMILY SSF52794 1 89 3.79E-17 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 78 308 2.9E-35 T 23-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 309 28.053 T 23-04-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Gene3D G3DSA:3.30.930.10 70 244 9.7E-42 T 23-04-2016 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Pfam PF03099 Biotin/lipoate A/B protein ligase family 113 207 8.0E-10 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 SUPERFAMILY SSF46785 3 59 1.01E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Gene3D G3DSA:1.10.10.10 1 61 6.1E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Gene3D G3DSA:2.30.30.100 263 308 2.5E-8 T 23-04-2016 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 SUPERFAMILY SSF50037 265 308 9.16E-6 T 23-04-2016 IPR008988 Transcriptional repressor, C-terminal SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 PANTHER PTHR12835 1 308 6.3E-52 T 23-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Pfam PF08279 HTH domain 5 57 5.3E-17 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 Pfam PF02237 Biotin protein ligase C terminal domain 263 309 7.8E-12 T 23-04-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 SPYM18_RS05945 10ddcfefa6468d1126cc25219cdee237 313 SUPERFAMILY SSF55681 66 246 7.46E-44 T 23-04-2016 SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 Pfam PF01121 Dephospho-CoA kinase 1 179 4.4E-50 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 2 187 3.4E-51 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 24.175 T 23-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 SUPERFAMILY SSF52540 1 193 1.59E-36 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 Gene3D G3DSA:3.40.50.300 1 193 1.1E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02405 781ecc17517bf07a9337f7895ca5a7f7 197 PANTHER PTHR10695 2 197 7.4E-62 T 23-04-2016 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 PANTHER PTHR21262 1 203 4.4E-115 T 23-04-2016 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 Gene3D G3DSA:1.10.287.860 148 202 8.6E-24 T 23-04-2016 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 SUPERFAMILY SSF81301 2 198 5.4E-58 T 23-04-2016 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 SMART SM00954 44 165 1.5E-43 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 6.5E-38 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 PANTHER PTHR21262:SF11 1 203 4.4E-115 T 23-04-2016 SPYM18_RS04685 021b3e4cb7ed614855f57066d85fc5b9 223 Gene3D G3DSA:3.30.460.10 2 145 9.0E-41 T 23-04-2016 SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 77 47.906 T 23-04-2016 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 17 75 9.2E-20 T 23-04-2016 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 PANTHER PTHR41270:SF1 2 77 1.7E-27 T 23-04-2016 SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 SUPERFAMILY SSF47336 5 77 1.23E-13 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 PANTHER PTHR41270 2 77 1.7E-27 T 23-04-2016 SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 Gene3D G3DSA:1.10.1200.10 1 77 4.4E-23 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS05740 ffb74926f8aec3af778a6c65eb6740cf 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 6.3E-11 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 Pfam PF00137 ATP synthase subunit C 5 64 1.7E-7 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 ProSitePatterns PS00605 ATP synthase c subunit signature. 30 51 - T 23-04-2016 IPR020537 ATPase, F0 complex, subunit C, DCCD-binding site SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 Gene3D G3DSA:1.20.20.10 5 64 2.8E-18 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 SUPERFAMILY SSF81333 6 64 1.2E-13 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 PRINTS PR00124 ATP synthase C subunit signature 23 38 1.0E-6 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 SPYM18_RS03510 09ebc5bee7e28e6a483ab67c38f15a2a 65 PRINTS PR00124 ATP synthase C subunit signature 40 65 1.0E-6 T 23-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 4.6E-170 T 23-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 SUPERFAMILY SSF48557 3 427 4.08E-135 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PANTHER PTHR11444 3 424 5.7E-169 T 23-04-2016 IPR000362 Fumarate lyase family SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 Gene3D G3DSA:1.10.40.30 358 428 4.7E-33 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 6.1E-23 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PANTHER PTHR11444:SF2 3 424 5.7E-169 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 SMART SM00998 349 429 4.2E-38 T 23-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 Gene3D G3DSA:1.10.275.10 2 90 3.3E-36 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.2E-25 T 23-04-2016 IPR000362 Fumarate lyase family SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.2E-25 T 23-04-2016 IPR000362 Fumarate lyase family SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.2E-25 T 23-04-2016 IPR000362 Fumarate lyase family SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.2E-25 T 23-04-2016 IPR000362 Fumarate lyase family SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 3.9E-9 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 3.9E-9 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 3.9E-9 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 Gene3D G3DSA:1.20.200.10 91 357 2.1E-89 T 23-04-2016 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 23-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 SPYM18_RS00320 263b1753ae25d379258d5973632aa968 430 Pfam PF00206 Lyase 7 286 1.0E-68 T 23-04-2016 IPR022761 Fumarate lyase, N-terminal SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 SUPERFAMILY SSF75304 421 477 3.53E-107 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 SUPERFAMILY SSF75304 2 393 3.53E-107 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 Gene3D G3DSA:3.90.1300.10 2 477 2.6E-104 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 PANTHER PTHR11895 5 390 1.3E-100 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 PANTHER PTHR11895 418 483 1.3E-100 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 Pfam PF01425 Amidase 22 468 1.0E-71 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 ProSitePatterns PS00571 Amidases signature. 145 176 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 PANTHER PTHR11895:SF35 5 390 1.3E-100 T 23-04-2016 SPYM18_RS04140 cb574142a518dae207a11ddb63745af6 484 PANTHER PTHR11895:SF35 418 483 1.3E-100 T 23-04-2016 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Gene3D G3DSA:3.40.50.300 398 569 2.7E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SUPERFAMILY SSF81767 231 349 3.01E-40 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Pfam PF07516 SecA Wing and Scaffold domain 571 779 2.6E-55 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Pfam PF02810 SEC-C motif 817 835 1.5E-9 T 23-04-2016 IPR004027 SEC-C motif SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 99 113 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 394 407 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 357 374 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 168 188 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 320 342 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 115 125 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PRINTS PR00906 SecA protein signature 61 85 5.8E-70 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Gene3D G3DSA:1.10.3060.10 601 781 1.6E-47 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SMART SM00957 5 383 2.4E-260 T 23-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 PANTHER PTHR30612 1 838 0.0 T 23-04-2016 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SUPERFAMILY SSF52540 12 226 6.1E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SUPERFAMILY SSF52540 349 396 6.1E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Pfam PF01043 SecA preprotein cross-linking domain 231 339 8.2E-34 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SUPERFAMILY SSF81886 573 825 1.96E-69 T 23-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Pfam PF07517 SecA DEAD-like domain 9 383 1.1E-121 T 23-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SUPERFAMILY SSF52540 397 567 4.63E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 782 19.108 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 497 2.7E-227 T 23-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 SMART SM00958 227 339 1.2E-56 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 ProSitePatterns PS01312 SecA family signature. 481 496 - T 23-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Gene3D G3DSA:3.90.1440.10 230 349 1.4E-41 T 23-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Gene3D G3DSA:3.40.50.300 10 226 1.1E-110 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08085 858dc243b69ea8a22c7e1961b1a1d2b3 839 Gene3D G3DSA:3.40.50.300 350 397 1.1E-110 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04740 786f720a660aea7b4c48ea688a9246ff 312 Pfam PF02424 ApbE family 10 287 4.5E-70 T 23-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 SPYM18_RS04740 786f720a660aea7b4c48ea688a9246ff 312 PIRSF PIRSF006268 2 311 1.0E-86 T 23-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 SPYM18_RS04740 786f720a660aea7b4c48ea688a9246ff 312 PANTHER PTHR30040:SF2 9 311 7.5E-89 T 23-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 SPYM18_RS04740 786f720a660aea7b4c48ea688a9246ff 312 SUPERFAMILY SSF143631 3 307 6.54E-86 T 23-04-2016 IPR003374 ApbE-like domain SPYM18_RS04740 786f720a660aea7b4c48ea688a9246ff 312 PANTHER PTHR30040 9 311 7.5E-89 T 23-04-2016 SPYM18_RS09135 96b8d589b4c09ee2c7c6dffc81953f17 153 PANTHER PTHR40028:SF1 1 150 7.5E-57 T 23-04-2016 SPYM18_RS09135 96b8d589b4c09ee2c7c6dffc81953f17 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 5 146 7.5E-48 T 23-04-2016 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 SPYM18_RS09135 96b8d589b4c09ee2c7c6dffc81953f17 153 PANTHER PTHR40028 1 150 7.5E-57 T 23-04-2016 SPYM18_RS09135 96b8d589b4c09ee2c7c6dffc81953f17 153 PIRSF PIRSF010607 1 151 3.5E-62 T 23-04-2016 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Pfam PF01018 GTP1/OBG 4 159 7.0E-61 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PANTHER PTHR11702:SF3 4 375 1.1E-165 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Pfam PF01926 50S ribosome-binding GTPase 162 285 1.5E-21 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 SUPERFAMILY SSF52540 153 339 6.37E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PANTHER PTHR11702 4 375 1.1E-165 T 23-04-2016 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Gene3D G3DSA:2.70.210.12 3 157 4.5E-58 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 ProSitePatterns PS00905 GTP1/OBG family signature. 214 227 - T 23-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 247 4.7E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 4.7E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 4.7E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 4.7E-34 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 367 436 5.1E-27 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 SUPERFAMILY SSF82051 3 159 4.58E-55 T 23-04-2016 IPR006169 GTP1/OBG domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Gene3D G3DSA:3.40.50.300 161 341 2.1E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 SUPERFAMILY SSF102741 364 437 5.23E-25 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 PIRSF PIRSF002401 1 385 1.0E-139 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 162 331 1.6E-12 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Hamap MF_01454 GTPase Obg [obg]. 3 338 46.938 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 Pfam PF09269 Domain of unknown function (DUF1967) 367 435 3.2E-26 T 23-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 SPYM18_RS05820 b19a6de3e7fb6202099ec935565fa1c9 437 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 337 7.1E-140 T 23-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 PANTHER PTHR22572:SF14 6 290 4.0E-109 T 23-04-2016 SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 PANTHER PTHR22572 6 290 4.0E-109 T 23-04-2016 SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 268 8.9E-110 T 23-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 Gene3D G3DSA:3.90.550.10 4 279 4.8E-70 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 Pfam PF00483 Nucleotidyl transferase 6 270 5.9E-33 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 SPYM18_RS01065 7dfc60427c3fa8f7df6a92824682b64b 299 SUPERFAMILY SSF53448 1 272 1.26E-65 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SMART SM00279 181 216 9.1E-18 T 23-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PANTHER PTHR10133 2 880 0.0 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 180 273 4.3E-32 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:3.30.420.10 306 492 9.2E-48 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:3.30.70.370 770 880 7.0E-63 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:3.30.70.370 613 662 7.0E-63 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 681 694 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 706 731 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 827 840 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 651 674 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 605 627 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 797 813 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 628 643 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 776 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PRINTS PR00868 DNA-polymerase family A (pol I) signature 743 754 3.2E-80 T 23-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 TIGRFAM TIGR00593 pola: DNA polymerase I 7 880 0.0 T 23-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:3.40.50.1010 5 193 3.6E-68 T 23-04-2016 IPR029060 PIN domain-like SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SUPERFAMILY SSF88723 3 178 2.36E-51 T 23-04-2016 IPR029060 PIN domain-like SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:1.10.150.20 663 769 1.1E-38 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 PANTHER PTHR10133:SF27 2 880 0.0 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Pfam PF00476 DNA polymerase family A 501 878 4.1E-151 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SUPERFAMILY SSF56672 472 880 1.01E-149 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SMART SM00474 301 468 3.6E-13 T 23-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:1.20.1060.10 493 612 1.8E-36 T 23-04-2016 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SUPERFAMILY SSF53098 306 468 6.07E-32 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SUPERFAMILY SSF47807 179 290 2.24E-33 T 23-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SMART SM00482 636 844 1.7E-117 T 23-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 178 2.1E-51 T 23-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 ProSitePatterns PS00447 DNA polymerase family A signature. 706 725 - T 23-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 SMART SM00475 5 270 4.2E-148 T 23-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 SPYM18_RS00990 0ea638397f689cde501d97170004b2c0 880 Gene3D G3DSA:1.10.150.20 194 255 3.8E-31 T 23-04-2016 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 67 3.0E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PANTHER PTHR11751 121 140 9.8E-28 T 23-04-2016 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PANTHER PTHR11751 1 74 9.8E-28 T 23-04-2016 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PANTHER PTHR11751:SF303 121 140 9.8E-28 T 23-04-2016 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PANTHER PTHR11751:SF303 1 74 9.8E-28 T 23-04-2016 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 5.1E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 5.1E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 SMART SM00345 8 67 5.7E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 Gene3D G3DSA:3.40.1410.10 65 231 4.6E-48 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 SMART SM00866 88 226 6.6E-35 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 Pfam PF07702 UTRA domain 88 226 1.4E-36 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 Gene3D G3DSA:1.10.10.10 3 64 2.1E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 SUPERFAMILY SSF46785 3 76 3.71E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04980 8acafb03a21ebe5778907029b7fa468c 232 SUPERFAMILY SSF64288 55 230 1.57E-45 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 SUPERFAMILY SSF52540 552 731 2.19E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 SUPERFAMILY SSF52540 447 513 2.19E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Gene3D G3DSA:3.40.50.300 289 515 9.6E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 5 731 1.2E-272 T 23-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Pfam PF14490 Helix-hairpin-helix containing domain 147 236 3.0E-26 T 23-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 SUPERFAMILY SSF52540 185 495 7.07E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 PANTHER PTHR10887:SF284 288 587 3.7E-110 T 23-04-2016 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 PANTHER PTHR10887:SF284 659 719 3.7E-110 T 23-04-2016 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Pfam PF13604 AAA domain 331 524 3.4E-43 T 23-04-2016 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 2 734 27.731 T 23-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 PANTHER PTHR10887 288 587 3.7E-110 T 23-04-2016 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 PANTHER PTHR10887 659 719 3.7E-110 T 23-04-2016 SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 SMART SM00382 344 494 2.8E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Pfam PF13538 UvrD-like helicase C-terminal domain 659 705 1.5E-15 T 23-04-2016 IPR027785 UvrD-like helicase C-terminal domain SPYM18_RS08230 bcf68312fa46994c19a71ef7a5865166 817 Gene3D G3DSA:3.40.50.300 658 741 5.9E-16 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 SUPERFAMILY SSF143034 2 62 1.06E-18 T 23-04-2016 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 23-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 PANTHER PTHR33343 1 61 4.7E-22 T 23-04-2016 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 4.2E-21 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.6E-16 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.6E-16 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.6E-16 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.205 T 23-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03730 040840ff663472a1278d7c4d2c57d7d8 65 Pfam PF01632 Ribosomal protein L35 2 61 1.2E-20 T 23-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 PANTHER PTHR11851:SF134 11 408 4.4E-74 T 23-04-2016 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 SUPERFAMILY SSF63411 249 426 5.87E-13 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 Pfam PF05193 Peptidase M16 inactive domain 184 361 4.7E-16 T 23-04-2016 IPR007863 Peptidase M16, C-terminal SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 Gene3D G3DSA:3.30.830.10 10 229 9.8E-39 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 SUPERFAMILY SSF63411 7 230 2.57E-34 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 PANTHER PTHR11851 11 408 4.4E-74 T 23-04-2016 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 Gene3D G3DSA:3.30.830.10 255 418 1.4E-4 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 SPYM18_RS09550 a25d8b2332607269cc1902a5e90b8084 429 Pfam PF00675 Insulinase (Peptidase family M16) 61 176 6.7E-14 T 23-04-2016 IPR011765 Peptidase M16, N-terminal SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 Gene3D G3DSA:1.10.260.40 5 65 1.5E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 SMART SM00530 8 63 1.3E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 PANTHER PTHR10245 1 71 7.4E-36 T 23-04-2016 SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 Pfam PF01381 Helix-turn-helix 9 62 3.9E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 PANTHER PTHR10245:SF50 1 71 7.4E-36 T 23-04-2016 SPYM18_RS06045 bcc70f94554757137bc3f6b21e925077 71 SUPERFAMILY SSF47413 3 68 3.67E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Gene3D G3DSA:1.10.240.10 232 315 6.3E-43 T 23-04-2016 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 SUPERFAMILY SSF52374 1 322 1.52E-106 T 23-04-2016 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 SMART SM00363 352 414 2.6E-4 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Gene3D G3DSA:3.40.50.620 2 231 4.9E-99 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Pfam PF01479 S4 domain 354 399 1.1E-8 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 PANTHER PTHR11766 1 415 1.2E-205 T 23-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Gene3D G3DSA:3.10.290.10 316 418 6.4E-33 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 417 1.4E-128 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 SUPERFAMILY SSF55174 321 417 8.51E-24 T 23-04-2016 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 4.1E-27 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 4.1E-27 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 4.1E-27 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 4.1E-27 T 23-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Pfam PF00579 tRNA synthetases class I (W and Y) 29 322 3.4E-83 T 23-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00620 35364f20887ccab231c68cf0d0dce408 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.563 T 23-04-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 3.2E-20 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Gene3D G3DSA:1.10.260.30 328 430 4.3E-38 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Gene3D G3DSA:1.20.120.140 3 90 2.1E-32 T 23-04-2016 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Pfam PF02978 Signal peptide binding domain 328 427 4.2E-31 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 PANTHER PTHR11564:SF7 1 435 5.8E-251 T 23-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 SMART SM00962 101 297 3.1E-110 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 6.6E-188 T 23-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 SUPERFAMILY SSF47446 328 429 1.96E-35 T 23-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 SUPERFAMILY SSF52540 43 355 5.44E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 SMART SM00963 2 87 5.5E-29 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.4E-75 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Gene3D G3DSA:3.40.50.300 98 298 3.8E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 SMART SM00382 100 408 1.7E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 439 33.982 T 23-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 SPYM18_RS04970 f9be779fbf7d91cbf95cf9125f52b11d 520 PANTHER PTHR11564 1 435 5.8E-251 T 23-04-2016 SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 Pfam PF13331 Domain of unknown function (DUF4093) 99 184 3.1E-30 T 23-04-2016 IPR025156 Ribonuclease M5, C-terminal domain SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 Pfam PF13662 Toprim domain 9 73 3.9E-5 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 7 182 3.1E-43 T 23-04-2016 IPR004466 Ribonuclease M5 GO:0043822 SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 Gene3D G3DSA:3.40.1360.20 5 126 6.8E-38 T 23-04-2016 SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 SUPERFAMILY SSF110455 5 124 1.33E-32 T 23-04-2016 SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 PANTHER PTHR39156 4 189 7.2E-71 T 23-04-2016 SPYM18_RS01205 112e9bd33dfa52ae3b6ee0aa8a70792a 189 Hamap MF_01469 Ribonuclease M5 [rnmV]. 7 187 29.857 T 23-04-2016 IPR004466 Ribonuclease M5 GO:0043822 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 Pfam PF00312 Ribosomal protein S15 8 88 8.4E-34 T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 SMART SM01387 8 88 2.0E-45 T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 SUPERFAMILY SSF47060 3 89 6.18E-34 T 23-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.659 T 23-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 Gene3D G3DSA:1.10.287.10 3 89 3.6E-38 T 23-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 PANTHER PTHR23321 1 89 2.7E-43 T 23-04-2016 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 23-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 3.7E-36 T 23-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08710 d2f63c56025e2c5f47892e082f6cd062 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 3.0E-40 T 23-04-2016 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 SUPERFAMILY SSF48168 22 168 1.57E-39 T 23-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 94 165 3.5E-10 T 23-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 4.4E-28 T 23-04-2016 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 698 4.5E-137 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 5.1E-22 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 5.1E-22 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 5.1E-22 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 5.1E-22 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 5.1E-22 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Gene3D G3DSA:3.20.70.20 344 507 1.6E-55 T 23-04-2016 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Gene3D G3DSA:3.20.70.20 569 674 1.6E-55 T 23-04-2016 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 Gene3D G3DSA:3.20.70.20 79 291 1.6E-55 T 23-04-2016 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 701 2.5E-147 T 23-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 PANTHER PTHR11573 8 701 7.3E-217 T 23-04-2016 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 719 0.0 T 23-04-2016 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS06005 e3414c82c1a128daacc006d5f6eb701b 719 SUPERFAMILY SSF51998 169 701 6.1E-168 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 SUPERFAMILY SSF50249 239 329 3.77E-11 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 SMART SM00479 426 592 8.4E-45 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF14480 DNA polymerase III polC-type N-terminus I 5 78 6.5E-17 T 23-04-2016 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Gene3D G3DSA:1.10.150.280 1398 1448 5.3E-8 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF02811 PHP domain 342 701 1.4E-48 T 23-04-2016 IPR004013 PHP domain GO:0003824 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF11490 DNA polymerase III polC-type N-terminus II 92 206 2.4E-26 T 23-04-2016 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 SUPERFAMILY SSF89550 352 413 2.98E-5 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Gene3D G3DSA:3.30.420.10 424 595 2.4E-58 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 SUPERFAMILY SSF53098 426 892 2.06E-92 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044:SF26 22 556 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044:SF26 1124 1437 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044:SF26 842 927 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044:SF26 945 1086 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF00929 Exonuclease 428 582 8.2E-33 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Gene3D G3DSA:2.40.50.140 230 330 1.4E-6 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 422 642 3.3E-38 T 23-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF14579 Helix-hairpin-helix motif 1378 1453 8.4E-6 T 23-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 236 1461 0.0 T 23-04-2016 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 842 1270 8.4E-90 T 23-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Gene3D G3DSA:3.20.20.140 636 812 6.9E-57 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Gene3D G3DSA:3.20.20.140 338 423 6.9E-57 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044 22 556 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044 1124 1437 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044 842 927 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 PANTHER PTHR23044 945 1086 0.0 T 23-04-2016 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 SMART SM00481 341 408 1.2E-24 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SPYM18_RS08740 5a9c237da9562445b9c8a5b340d5fd48 1465 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1465 427.488 T 23-04-2016 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08980 46392837519a72d3b11b528be91f41b5 422 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 62 292 5.8E-9 T 23-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SPYM18_RS08980 46392837519a72d3b11b528be91f41b5 422 PANTHER PTHR32347:SF14 19 420 7.7E-32 T 23-04-2016 SPYM18_RS08980 46392837519a72d3b11b528be91f41b5 422 PANTHER PTHR32347 19 420 7.7E-32 T 23-04-2016 SPYM18_RS08980 46392837519a72d3b11b528be91f41b5 422 Gene3D G3DSA:2.40.50.100 83 108 2.9E-6 T 23-04-2016 SPYM18_RS08980 46392837519a72d3b11b528be91f41b5 422 Gene3D G3DSA:2.40.50.100 212 229 2.9E-6 T 23-04-2016 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 226 360 8.3E-61 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 59 207 4.6E-52 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 225 352 34.611 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 PANTHER PTHR10173 330 368 8.4E-89 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 PANTHER PTHR10173 61 201 8.4E-89 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 SUPERFAMILY SSF55068 53 218 2.22E-63 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Gene3D G3DSA:3.30.1060.10 40 208 2.1E-67 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 SUPERFAMILY SSF51316 226 365 3.51E-56 T 23-04-2016 IPR011057 Mss4-like SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 PANTHER PTHR10173:SF40 330 368 8.4E-89 T 23-04-2016 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 PANTHER PTHR10173:SF40 61 201 8.4E-89 T 23-04-2016 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Pfam PF01625 Peptide methionine sulfoxide reductase 61 208 8.0E-59 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Gene3D G3DSA:2.170.150.20 220 367 6.6E-59 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Pfam PF01641 SelR domain 231 351 5.8E-47 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS06775 55bd9225b8beb13e4ad5b558d4958c26 368 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 58 213 35.708 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 147 166 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 200 219 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 606 623 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 414 429 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 353 367 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00943 Copper-transporting ATPase signature 127 145 5.8E-16 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF55008 2 74 1.27E-20 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 23-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF81665 678 728 2.48E-13 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF81665 198 234 2.48E-13 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF81665 331 425 2.48E-13 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Pfam PF00403 Heavy-metal-associated domain 6 65 3.8E-16 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF81653 236 330 1.1E-22 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF56784 429 449 3.09E-60 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 SUPERFAMILY SSF56784 487 736 3.09E-60 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Gene3D G3DSA:2.70.150.10 225 331 1.1E-26 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 1.6E-27 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 280 294 1.6E-27 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 445 1.6E-27 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 664 1.6E-27 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 1.6E-27 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 PANTHER PTHR24093 1 739 5.8E-241 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Gene3D G3DSA:3.40.50.1000 402 447 3.4E-58 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Gene3D G3DSA:3.40.50.1000 557 698 3.4E-58 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 433 439 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Pfam PF00702 haloacid dehalogenase-like hydrolase 427 643 4.6E-41 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Pfam PF00122 E1-E2 ATPase 201 422 1.1E-66 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 162 738 9.1E-193 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 202 707 1.1E-90 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Gene3D G3DSA:3.30.70.100 5 77 6.6E-23 T 23-04-2016 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 Gene3D G3DSA:3.40.1110.10 450 556 2.4E-16 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 SPYM18_RS07405 5ffe3056781ba8ce23371fcf40bc7379 743 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 145 739 1.5E-181 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF55326 195 231 3.17E-32 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF55326 289 429 3.17E-32 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Gene3D G3DSA:3.30.1330.10 647 806 1.4E-24 T 23-04-2016 IPR016188 PurM-like, N-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Gene3D G3DSA:3.30.1330.10 286 430 3.6E-54 T 23-04-2016 IPR016188 PurM-like, N-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Gene3D G3DSA:3.30.1330.10 220 235 3.6E-54 T 23-04-2016 IPR016188 PurM-like, N-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF56042 813 968 4.4E-11 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 PANTHER PTHR10099:SF1 2 235 4.8E-265 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 PANTHER PTHR10099:SF1 262 1241 4.8E-265 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SMART SM01211 976 1238 1.7E-104 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF52317 974 1238 9.31E-66 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 976 1238 2.9E-79 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 PANTHER PTHR10099 2 235 4.8E-265 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 PANTHER PTHR10099 262 1241 4.8E-265 T 23-04-2016 SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Pfam PF02769 AIR synthase related protein, C-terminal domain 439 590 1.4E-23 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 Gene3D G3DSA:3.40.50.880 979 1217 7.2E-15 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 3 1238 0.0 T 23-04-2016 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF56042 440 605 1.34E-37 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00270 aed42216a55ce5a18a3ce7f42d386450 1241 SUPERFAMILY SSF55326 629 811 5.23E-36 T 23-04-2016 SPYM18_RS04655 4272ef63180b2e099ec65a73f5ed471a 231 Gene3D G3DSA:3.40.50.880 2 229 7.9E-49 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS04655 4272ef63180b2e099ec65a73f5ed471a 231 PANTHER PTHR11922 30 229 4.1E-41 T 23-04-2016 SPYM18_RS04655 4272ef63180b2e099ec65a73f5ed471a 231 PANTHER PTHR11922:SF18 30 229 4.1E-41 T 23-04-2016 SPYM18_RS04655 4272ef63180b2e099ec65a73f5ed471a 231 Pfam PF07722 Peptidase C26 4 211 6.3E-70 T 23-04-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 SPYM18_RS04655 4272ef63180b2e099ec65a73f5ed471a 231 SUPERFAMILY SSF52317 1 229 5.94E-35 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 PIRSF PIRSF036692 4 223 2.0E-104 T 23-04-2016 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 Pfam PF03315 Serine dehydratase beta chain 8 135 1.2E-14 T 23-04-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 PANTHER PTHR30182 1 223 1.1E-109 T 23-04-2016 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 PANTHER PTHR30182:SF2 1 223 1.1E-109 T 23-04-2016 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 Pfam PF01842 ACT domain 154 214 4.0E-9 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 SUPERFAMILY SSF55021 140 220 6.36E-19 T 23-04-2016 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 Gene3D G3DSA:3.30.70.260 139 220 4.2E-23 T 23-04-2016 SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 SUPERFAMILY SSF143548 22 141 8.89E-31 T 23-04-2016 IPR029009 Allosteric substrate binding domain SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 Gene3D G3DSA:3.30.1330.90 16 138 3.0E-31 T 23-04-2016 IPR029009 Allosteric substrate binding domain SPYM18_RS09510 0010dd24abd979778d34a4b08d4d40e1 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 201 1.1E-67 T 23-04-2016 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PANTHER PTHR30075:SF2 1 679 0.0 T 23-04-2016 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 676 26.328 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 547 4.2E-197 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 4.3E-32 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 4.3E-32 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 4.3E-32 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 4.3E-32 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 4.3E-32 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 SUPERFAMILY SSF109604 335 492 3.45E-17 T 23-04-2016 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 PANTHER PTHR30075 1 679 0.0 T 23-04-2016 SPYM18_RS07305 0550fbb67d41ddbd0c1ff69fc0986d42 679 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 676 7.5E-209 T 23-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 PANTHER PTHR39340:SF1 1 327 6.9E-128 T 23-04-2016 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 Hamap MF_00734 Tagatose 1,6-diphosphate aldolase [lacD]. 1 327 209.474 T 23-04-2016 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 Gene3D G3DSA:3.20.20.70 6 326 3.5E-132 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 TIGRFAM TIGR01232 lacD: tagatose 1,6-diphosphate aldolase 5 326 6.1E-180 T 23-04-2016 IPR005927 Tagatose 1,6-diphosphate aldolase GO:0009024|GO:0019512 KEGG: 00052+4.1.2.40|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 SMART SM01133 22 284 3.5E-29 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 PANTHER PTHR39340 1 327 6.9E-128 T 23-04-2016 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 Pfam PF01791 DeoC/LacD family aldolase 22 283 8.9E-78 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS08580 68d41d22ec24cf5f334fdb21c9827340 327 SUPERFAMILY SSF51569 9 323 5.13E-69 T 23-04-2016 SPYM18_RS07760 be5ac70163368c082f7621fcc96b280a 312 TIGRFAM TIGR01714 phage_rep_org_N: phage replisome organizer, putative, N-terminal region 9 127 3.4E-51 T 23-04-2016 IPR010056 Phage replisome organiser, N-terminal domain SPYM18_RS07760 be5ac70163368c082f7621fcc96b280a 312 Pfam PF09681 N-terminal phage replisome organiser (Phage_rep_org_N) 9 125 2.3E-35 T 23-04-2016 IPR010056 Phage replisome organiser, N-terminal domain SPYM18_RS07760 be5ac70163368c082f7621fcc96b280a 312 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 206 278 3.9E-24 T 23-04-2016 IPR011741 Phage conserved hypothetical protein, C-terminal SPYM18_RS07760 be5ac70163368c082f7621fcc96b280a 312 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 206 277 6.5E-27 T 23-04-2016 IPR011741 Phage conserved hypothetical protein, C-terminal SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 SMART SM00382 110 260 2.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 SUPERFAMILY SSF57716 11 46 5.13E-11 T 23-04-2016 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 312 390 7.0E-18 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 SUPERFAMILY SSF52540 60 391 2.82E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 409 51.289 T 23-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Gene3D G3DSA:1.10.8.60 311 407 5.5E-38 T 23-04-2016 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 SMART SM00994 10 49 6.5E-21 T 23-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Pfam PF07724 AAA domain (Cdc48 subfamily) 110 305 3.0E-49 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 SMART SM01086 312 406 7.3E-34 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 PANTHER PTHR11262:SF4 4 406 2.8E-231 T 23-04-2016 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Gene3D G3DSA:3.40.50.300 62 252 6.9E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Gene3D G3DSA:3.40.50.300 289 306 6.9E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 PANTHER PTHR11262 4 406 2.8E-231 T 23-04-2016 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 Pfam PF06689 ClpX C4-type zinc finger 12 48 4.5E-17 T 23-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 SPYM18_RS04070 d6742ec2194ca3582be0402caf19f6b1 409 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 7 406 7.9E-195 T 23-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 SPYM18_RS00295 f3e3d28037b40b3f6232c682d4890ee6 374 Pfam PF05257 CHAP domain 58 145 3.1E-12 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS00295 f3e3d28037b40b3f6232c682d4890ee6 374 SUPERFAMILY SSF54001 43 177 9.81E-25 T 23-04-2016 SPYM18_RS00295 f3e3d28037b40b3f6232c682d4890ee6 374 Pfam PF08460 Bacterial SH3 domain 193 256 7.5E-26 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 Gene3D G3DSA:3.30.420.140 1 137 1.3E-48 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 PANTHER PTHR33317 1 136 7.7E-43 T 23-04-2016 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 6.7E-43 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 SMART SM00732 1 103 3.2E-40 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 26.276 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 SUPERFAMILY SSF53098 1 137 2.28E-42 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS09285 2860f83fb068863d6d34c2af5a70faba 139 Pfam PF03652 Holliday junction resolvase 1 136 4.2E-42 T 23-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 Hamap MF_01816 Tyrosine recombinase XerS [xerS]. 1 356 67.41 T 23-04-2016 IPR023670 Tyrosine recombinase XerS GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 PANTHER PTHR30349 188 355 1.3E-101 T 23-04-2016 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 PANTHER PTHR30349 15 159 1.3E-101 T 23-04-2016 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 PANTHER PTHR30349:SF17 188 355 1.3E-101 T 23-04-2016 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 PANTHER PTHR30349:SF17 15 159 1.3E-101 T 23-04-2016 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 33 122 2.7E-7 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 Gene3D G3DSA:1.10.443.10 169 353 3.3E-37 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 Gene3D G3DSA:1.10.150.130 32 123 5.7E-12 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS04960 726763927017f3cb8047614133291d03 356 SUPERFAMILY SSF56349 20 353 1.12E-34 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS04960 726763927017f3cb8047614133291d03 356 Pfam PF00589 Phage integrase family 177 344 6.9E-24 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 2.0E-58 T 23-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 6 109 2.4E-19 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 Gene3D G3DSA:3.90.470.20 1 116 8.8E-35 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 SUPERFAMILY SSF56214 1 116 2.62E-33 T 23-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 1.5E-24 T 23-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 21.531 T 23-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS08080 2378130550b5c82d726c8cfe71bb0277 118 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 116 9.4E-22 T 23-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 Pfam PF14278 Transcriptional regulator C-terminal region 80 153 4.4E-8 T 23-04-2016 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 PANTHER PTHR30328 4 172 2.8E-30 T 23-04-2016 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 SUPERFAMILY SSF46689 4 70 1.74E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 Gene3D G3DSA:1.10.357.10 9 172 6.7E-16 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.1E-6 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPYM18_RS03900 d042445014d0eff3530b966c3c9149a3 173 PANTHER PTHR30328:SF20 4 172 2.8E-30 T 23-04-2016 SPYM18_RS01060 983e7f147bfefce3dee446172a168b52 223 SUPERFAMILY SSF144091 5 193 2.35E-37 T 23-04-2016 SPYM18_RS01060 983e7f147bfefce3dee446172a168b52 223 PANTHER PTHR22936:SF4 53 223 9.5E-32 T 23-04-2016 SPYM18_RS01060 983e7f147bfefce3dee446172a168b52 223 PANTHER PTHR22936 53 223 9.5E-32 T 23-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 SPYM18_RS01060 983e7f147bfefce3dee446172a168b52 223 Gene3D G3DSA:1.20.1540.10 7 189 9.7E-37 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SPYM18_RS01060 983e7f147bfefce3dee446172a168b52 223 Pfam PF01694 Rhomboid family 54 190 7.3E-32 T 23-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.30.980.10 66 130 2.6E-36 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.30.980.10 185 220 2.6E-36 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 SMART SM00863 167 216 9.6E-24 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.30.54.20 131 184 1.1E-22 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 SUPERFAMILY SSF55186 63 238 6.54E-63 T 23-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 SUPERFAMILY SSF52954 531 635 2.42E-32 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PANTHER PTHR11451 1 642 0.0 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.30.930.10 239 534 8.2E-109 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 324 533 5.6E-35 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 SUPERFAMILY SSF55681 240 530 5.97E-99 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 636 8.1E-230 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 538 550 6.1E-47 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 468 496 6.1E-47 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 357 6.1E-47 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 362 385 6.1E-47 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PRINTS PR01047 Threonyl-tRNA synthetase signature 511 524 6.1E-47 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.40.50.800 535 640 2.1E-35 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Gene3D G3DSA:3.10.20.30 1 64 3.2E-25 T 23-04-2016 IPR012675 Beta-grasp domain SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 639 34.453 T 23-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 PANTHER PTHR11451:SF5 1 642 0.0 T 23-04-2016 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 167 216 6.6E-16 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 SUPERFAMILY SSF81271 2 61 1.18E-16 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Pfam PF03129 Anticodon binding domain 545 634 2.8E-23 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS02495 f82d2377383e5136d9f58de5ab4a921e 647 Pfam PF02824 TGS domain 2 61 1.6E-12 T 23-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 SPYM18_RS02875 8c0ad24e4d0b1286f41fab529b91566a 126 Gene3D G3DSA:3.10.20.30 43 122 1.9E-4 T 23-04-2016 IPR012675 Beta-grasp domain SPYM18_RS02875 8c0ad24e4d0b1286f41fab529b91566a 126 Pfam PF14478 Domain of unknown function (DUF4430) 59 122 4.5E-22 T 23-04-2016 IPR027954 Domain of unknown function DUF4430 SPYM18_RS09540 5ea8b04347e2228d27db075a2e729d2f 180 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 6 169 9.3E-52 T 23-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 SPYM18_RS09540 5ea8b04347e2228d27db075a2e729d2f 180 PANTHER PTHR14269 6 168 5.1E-44 T 23-04-2016 SPYM18_RS09540 5ea8b04347e2228d27db075a2e729d2f 180 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 74 2.4E-18 T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SPYM18_RS09540 5ea8b04347e2228d27db075a2e729d2f 180 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 23-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 SPYM18_RS09540 5ea8b04347e2228d27db075a2e729d2f 180 PIRSF PIRSF000847 3 180 7.1E-49 T 23-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 PIRSF PIRSF037748 1 299 3.2E-107 T 23-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 6 290 2.4E-57 T 23-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 PANTHER PTHR10954:SF12 14 300 9.0E-82 T 23-04-2016 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 Gene3D G3DSA:3.30.420.10 85 248 5.7E-37 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 PANTHER PTHR10954 14 300 9.0E-82 T 23-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 SUPERFAMILY SSF53098 84 296 3.79E-48 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 298 37.677 T 23-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 Pfam PF01351 Ribonuclease HII 86 291 1.6E-53 T 23-04-2016 IPR024567 Ribonuclease HII/HIII domain SPYM18_RS08220 39225d90b2efc15930bcda23a1738446 300 Pfam PF11858 Domain of unknown function (DUF3378) 4 76 2.0E-19 T 23-04-2016 IPR024568 Ribonuclease HIII, N-terminal SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 PANTHER PTHR39161 2 109 1.7E-59 T 23-04-2016 SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 PANTHER PTHR39161 127 250 1.7E-59 T 23-04-2016 SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 PIRSF PIRSF029008 1 253 1.1E-74 T 23-04-2016 IPR008681 Negative regulator of genetic competence, MecA SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 PANTHER PTHR39161:SF1 2 109 1.7E-59 T 23-04-2016 SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 PANTHER PTHR39161:SF1 127 250 1.7E-59 T 23-04-2016 SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 Hamap MF_01124 Adapter protein MecA [mecA]. 1 251 25.247 T 23-04-2016 IPR008681 Negative regulator of genetic competence, MecA SPYM18_RS01295 4c03d9589c093a3973f44015dd4126ae 253 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 247 6.6E-41 T 23-04-2016 IPR008681 Negative regulator of genetic competence, MecA SPYM18_RS00815 e4e07aca2f416c5c986233059f493779 226 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 1 127 9.0E-70 T 23-04-2016 IPR013559 YheO-like SPYM18_RS00815 e4e07aca2f416c5c986233059f493779 226 PANTHER PTHR35568 3 225 1.9E-34 T 23-04-2016 SPYM18_RS00815 e4e07aca2f416c5c986233059f493779 226 Pfam PF13309 HTH domain 162 220 8.0E-20 T 23-04-2016 SPYM18_RS00815 e4e07aca2f416c5c986233059f493779 226 Pfam PF08348 YheO-like PAS domain 6 118 5.7E-30 T 23-04-2016 IPR013559 YheO-like SPYM18_RS00815 e4e07aca2f416c5c986233059f493779 226 PANTHER PTHR35568:SF1 3 225 1.9E-34 T 23-04-2016 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 SUPERFAMILY SSF53328 2 203 5.63E-59 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 303 1.8E-90 T 23-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 Gene3D G3DSA:3.10.25.10 208 308 1.2E-29 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 Pfam PF00551 Formyl transferase 4 177 6.3E-33 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 PANTHER PTHR11138 2 299 6.4E-102 T 23-04-2016 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 SUPERFAMILY SSF50486 205 303 4.4E-30 T 23-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 299 4.7E-25 T 23-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 302 32.527 T 23-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 Gene3D G3DSA:3.40.50.170 2 205 1.7E-61 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS07075 9442cdc35724df6d8f4a6d76c09c2529 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 23-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Gene3D G3DSA:3.30.300.10 143 244 1.7E-49 T 23-04-2016 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Gene3D G3DSA:3.30.300.10 255 395 2.1E-67 T 23-04-2016 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 393 3.3E-175 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 394 56.013 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 PIRSF PIRSF000497 1 395 4.0E-173 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Pfam PF02772 S-adenosylmethionine synthetase, central domain 125 242 1.7E-49 T 23-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Gene3D G3DSA:3.30.300.10 12 142 4.3E-43 T 23-04-2016 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 SUPERFAMILY SSF55973 244 394 2.35E-67 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 PANTHER PTHR11964 1 392 2.4E-263 T 23-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 SUPERFAMILY SSF55973 5 110 9.42E-42 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 101 1.3E-38 T 23-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 244 383 1.5E-67 T 23-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 126 136 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 SUPERFAMILY SSF55973 122 243 1.41E-52 T 23-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS05935 0906ca96364f472cd9d7b5327a1ef005 398 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 270 278 - T 23-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 SPYM18_RS09440 0433ccf5e458806989dee08746a5d21f 213 Pfam PF00293 NUDIX domain 27 130 2.9E-12 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 SPYM18_RS09440 0433ccf5e458806989dee08746a5d21f 213 ProSitePatterns PS00893 Nudix box signature. 54 75 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPYM18_RS09440 0433ccf5e458806989dee08746a5d21f 213 PANTHER PTHR12992 12 187 2.3E-28 T 23-04-2016 SPYM18_RS09440 0433ccf5e458806989dee08746a5d21f 213 Gene3D G3DSA:3.90.79.10 16 194 1.4E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS09440 0433ccf5e458806989dee08746a5d21f 213 SUPERFAMILY SSF55811 19 186 6.36E-24 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Gene3D G3DSA:2.40.33.10 95 196 5.3E-20 T 23-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Gene3D G3DSA:3.40.1380.20 355 500 8.0E-48 T 23-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PANTHER PTHR11817:SF3 1 16 6.8E-194 T 23-04-2016 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PANTHER PTHR11817:SF3 38 499 6.8E-194 T 23-04-2016 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 SUPERFAMILY SSF50800 92 194 3.84E-17 T 23-04-2016 IPR011037 Pyruvate kinase-like, insert domain SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Pfam PF00224 Pyruvate kinase, barrel domain 3 370 9.0E-146 T 23-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Pfam PF02887 Pyruvate kinase, alpha/beta domain 386 496 6.3E-35 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 341 357 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 322 340 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 81 97 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 214 228 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 245 271 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 297 321 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PRINTS PR01050 Pyruvate kinase family signature 272 296 2.1E-66 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PANTHER PTHR11817 1 16 6.8E-194 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 PANTHER PTHR11817 38 499 6.8E-194 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 SUPERFAMILY SSF52935 351 499 2.09E-40 T 23-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 37 499 5.1E-149 T 23-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Gene3D G3DSA:3.20.20.60 197 354 2.2E-97 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 Gene3D G3DSA:3.20.20.60 4 94 2.2E-97 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 SUPERFAMILY SSF51621 2 96 1.78E-84 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS05320 764f2aa574f3edb8c18a95e9f79f2245 500 SUPERFAMILY SSF51621 184 367 1.78E-84 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS06820 b719fdf3ed2372e76c24c81ffa68a75e 131 SUPERFAMILY SSF47794 79 125 5.81E-8 T 23-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 SPYM18_RS06820 b719fdf3ed2372e76c24c81ffa68a75e 131 Gene3D G3DSA:1.10.150.20 79 124 8.5E-8 T 23-04-2016 SPYM18_RS06820 b719fdf3ed2372e76c24c81ffa68a75e 131 Pfam PF14520 Helix-hairpin-helix domain 78 124 4.9E-6 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 SUPERFAMILY SSF46785 13 101 2.02E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 Gene3D G3DSA:3.40.190.10 103 191 3.8E-9 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 SUPERFAMILY SSF53850 102 308 9.77E-25 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 15 75 3.8E-14 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 Pfam PF03466 LysR substrate binding domain 101 296 3.0E-27 T 23-04-2016 IPR005119 LysR, substrate-binding SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 PANTHER PTHR30419:SF8 8 308 8.8E-81 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 PANTHER PTHR30419 8 308 8.8E-81 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 Gene3D G3DSA:3.40.190.10 192 278 1.8E-16 T 23-04-2016 SPYM18_RS07100 e89e42fe2f0f771883ca8282bbd53bd3 310 Gene3D G3DSA:1.10.10.10 12 92 1.3E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184 1 93 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 SUPERFAMILY SSF50615 2 70 1.81E-11 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184:SF7 183 582 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Gene3D G3DSA:1.10.1140.10 451 507 3.2E-29 T 23-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Gene3D G3DSA:1.10.1140.10 539 589 3.2E-29 T 23-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 427 436 - T 23-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 589 49.928 T 23-04-2016 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 SUPERFAMILY SSF52540 185 441 3.35E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184 183 582 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184 132 137 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 204 3.4E-42 T 23-04-2016 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Gene3D G3DSA:3.40.50.300 150 436 7.7E-103 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 SUPERFAMILY SSF47917 453 534 1.7E-24 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 8.7E-11 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184:SF7 1 93 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 PANTHER PTHR15184:SF7 132 137 3.9E-258 T 23-04-2016 SPYM18_RS00860 3a0a0da4e24ba797f9b16e0da145a419 591 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 213 436 7.6E-94 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS05520 56879b2a56ac56eb82d8d52309ce88d6 541 TIGRFAM TIGR01641 phageSPP1_gp7: phage head morphogenesis protein, SPP1 gp7 family 209 311 1.6E-13 T 23-04-2016 IPR006528 Phage head morphogenesis domain SPYM18_RS05520 56879b2a56ac56eb82d8d52309ce88d6 541 Pfam PF04233 Phage Mu protein F like protein 205 308 1.8E-11 T 23-04-2016 IPR006528 Phage head morphogenesis domain SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 Gene3D G3DSA:3.40.50.10440 11 181 3.5E-75 T 23-04-2016 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 2.2E-150 T 23-04-2016 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00563+2.7.-.-|UniPathway: UPA00616 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 SUPERFAMILY SSF82549 11 329 1.02E-121 T 23-04-2016 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 PANTHER PTHR28629 1 329 3.6E-161 T 23-04-2016 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 Gene3D G3DSA:3.30.1180.20 184 329 4.2E-50 T 23-04-2016 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 Pfam PF02733 Dak1 domain 17 327 2.0E-118 T 23-04-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 SPYM18_RS02530 b2e7ae56e2fd7d48be31784c75a6e21f 329 PANTHER PTHR28629:SF2 1 329 3.6E-161 T 23-04-2016 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 SMART SM00342 397 480 8.7E-26 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 Gene3D G3DSA:1.10.10.60 434 484 4.9E-17 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 SUPERFAMILY SSF52172 1 146 4.41E-32 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 Gene3D G3DSA:3.40.50.2300 1 129 5.2E-32 T 23-04-2016 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 434 476 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 PANTHER PTHR26402 2 118 2.6E-35 T 23-04-2016 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 SMART SM00448 2 116 1.1E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 SUPERFAMILY SSF46689 433 485 1.39E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 449 464 9.9E-6 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 464 480 9.9E-6 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 Pfam PF00072 Response regulator receiver domain 4 116 1.2E-24 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 Gene3D G3DSA:1.10.10.60 376 433 5.6E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06870 7b2380a3d5b66b408be69415ddbb778d 494 Pfam PF12833 Helix-turn-helix domain 403 482 2.5E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PANTHER PTHR21342:SF1 1 158 3.5E-55 T 23-04-2016 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 6 159 5.1E-61 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 4 161 30.901 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PANTHER PTHR21342 1 158 3.5E-55 T 23-04-2016 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 62 1.2E-16 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 SUPERFAMILY SSF52374 4 158 3.58E-41 T 23-04-2016 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 4 22 1.9E-35 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 115 137 1.9E-35 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 88 104 1.9E-35 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 22 43 1.9E-35 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 51 75 1.9E-35 T 23-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 Gene3D G3DSA:3.40.50.620 4 159 2.9E-48 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06700 82b29a1549104296072c823c13d189d1 163 Pfam PF01467 Cytidylyltransferase-like 7 136 3.6E-17 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 4.4E-32 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 448 2.2E-165 T 23-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 Gene3D G3DSA:1.10.860.10 10 112 2.2E-34 T 23-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 Gene3D G3DSA:3.40.50.300 171 448 2.0E-104 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 PANTHER PTHR30153 2 453 3.7E-194 T 23-04-2016 SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 SUPERFAMILY SSF48024 8 119 5.36E-35 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 SUPERFAMILY SSF52540 183 439 1.49E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09480 ecb030c649192f620e0c74f3d0ef0463 453 Pfam PF03796 DnaB-like helicase C terminal domain 185 445 3.4E-109 T 23-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 PANTHER PTHR24220 3 236 8.1E-95 T 23-04-2016 SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 Pfam PF00005 ABC transporter 18 162 2.1E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 Gene3D G3DSA:3.40.50.300 1 228 2.4E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 SUPERFAMILY SSF52540 2 221 3.88E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 PANTHER PTHR24220:SF581 3 236 8.1E-95 T 23-04-2016 SPYM18_RS02175 f0cbfb0cde425e301f8cf3a3a18c8c4f 241 SMART SM00382 27 211 8.9E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 233 33.018 T 23-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 226 5.7E-71 T 23-04-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 Gene3D G3DSA:3.30.470.20 93 219 2.8E-51 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 Gene3D G3DSA:3.30.200.20 5 92 5.5E-37 T 23-04-2016 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 SUPERFAMILY SSF56104 12 231 2.19E-78 T 23-04-2016 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 Pfam PF01259 SAICAR synthetase 5 228 6.4E-61 T 23-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 ProSitePatterns PS01058 SAICAR synthetase signature 2. 172 180 - T 23-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 PANTHER PTHR11609:SF2 3 231 3.7E-113 T 23-04-2016 SPYM18_RS00265 3303bf79721f036f0266acd8307c6877 234 PANTHER PTHR11609 3 231 3.7E-113 T 23-04-2016 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 PANTHER PTHR20941 14 266 2.4E-110 T 23-04-2016 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 14 264 3.3E-103 T 23-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 48 61 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 14 29 - T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 SUPERFAMILY SSF51717 7 265 1.01E-94 T 23-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 Pfam PF00809 Pterin binding enzyme 15 250 3.9E-83 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 Gene3D G3DSA:3.20.20.20 11 265 6.1E-106 T 23-04-2016 IPR000489 Pterin-binding domain GO:0042558 SPYM18_RS04565 8e94f903ff910a61b24bff75221017f9 266 PANTHER PTHR20941:SF1 14 266 2.4E-110 T 23-04-2016 SPYM18_RS09600 5a8d05787e6630e4abdef6697142f203 290 PANTHER PTHR33545 6 279 1.1E-80 T 23-04-2016 SPYM18_RS09600 5a8d05787e6630e4abdef6697142f203 290 PANTHER PTHR33545:SF6 6 279 1.1E-80 T 23-04-2016 SPYM18_RS09600 5a8d05787e6630e4abdef6697142f203 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 4.1E-15 T 23-04-2016 IPR019264 Domain of unknown function DUF2179 SPYM18_RS09600 5a8d05787e6630e4abdef6697142f203 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 5.3E-59 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS09600 5a8d05787e6630e4abdef6697142f203 290 PIRSF PIRSF006483 1 278 1.7E-76 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 Hamap MF_01568 UPF0374 protein . 1 175 49.33 T 23-04-2016 IPR016882 Uncharacterised protein family UPF0374 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 PIRSF PIRSF028345 1 177 2.1E-75 T 23-04-2016 IPR016882 Uncharacterised protein family UPF0374 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 PANTHER PTHR39159:SF1 1 176 3.6E-69 T 23-04-2016 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 Pfam PF04167 Protein of unknown function (DUF402) 60 124 1.5E-16 T 23-04-2016 IPR007295 Domain of unknown function DUF402 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 PANTHER PTHR39159 1 176 3.6E-69 T 23-04-2016 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 Gene3D G3DSA:2.40.380.10 4 170 4.4E-43 T 23-04-2016 IPR007295 Domain of unknown function DUF402 SPYM18_RS06945 439a63c1e47fc7a62def7f8a411d6909 177 SUPERFAMILY SSF159234 3 170 1.31E-31 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 Gene3D G3DSA:3.40.190.10 120 229 3.5E-23 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 268 2.5E-58 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 SUPERFAMILY SSF53850 4 270 3.57E-64 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 SMART SM00062 42 270 2.3E-65 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 PANTHER PTHR18966 39 271 2.5E-36 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 PANTHER PTHR18966:SF152 39 271 2.5E-36 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 Gene3D G3DSA:3.40.190.10 230 272 4.0E-39 T 23-04-2016 SPYM18_RS05290 4ba007acd1eb45061319322fdd00be6d 278 Gene3D G3DSA:3.40.190.10 39 119 4.0E-39 T 23-04-2016 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 SUPERFAMILY SSF54821 106 205 1.83E-37 T 23-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 37.928 T 23-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 Pfam PF07650 KH domain 38 109 4.3E-21 T 23-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 SMART SM00322 59 124 9.7E-8 T 23-04-2016 IPR004087 K Homology domain GO:0003676 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 SUPERFAMILY SSF54814 2 105 1.28E-37 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 PANTHER PTHR11760:SF19 2 214 1.5E-132 T 23-04-2016 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 Gene3D G3DSA:3.30.1140.32 108 206 1.4E-43 T 23-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 4.0E-92 T 23-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 Gene3D G3DSA:3.30.300.20 17 106 3.6E-33 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 PANTHER PTHR11760 2 214 1.5E-132 T 23-04-2016 SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 23-04-2016 IPR018280 Ribosomal protein S3, conserved site SPYM18_RS00400 f71e836405d161cfe913ca37cd8c8fb2 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 2.0E-39 T 23-04-2016 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 Gene3D G3DSA:3.40.50.450 1 169 2.1E-55 T 23-04-2016 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 PANTHER PTHR38440 2 168 4.8E-35 T 23-04-2016 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 PIRSF PIRSF021290 1 171 2.0E-64 T 23-04-2016 IPR010697 Protein of unknown function DUF1273 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 Hamap MF_01575 UPF0398 protein . 1 171 33.775 T 23-04-2016 IPR010697 Protein of unknown function DUF1273 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 SUPERFAMILY SSF102405 1 168 1.28E-52 T 23-04-2016 SPYM18_RS07150 f2098b4bfc68a294aaeeb70ce9c8ca24 171 Pfam PF06908 Protein of unknown function (DUF1273) 4 165 6.9E-61 T 23-04-2016 IPR010697 Protein of unknown function DUF1273 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 SUPERFAMILY SSF52218 5 146 1.88E-39 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 TIGRFAM TIGR01753 flav_short: flavodoxin 5 142 2.1E-49 T 23-04-2016 IPR010087 Flavodoxin, short chain GO:0010181 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 Pfam PF00258 Flavodoxin 6 132 2.1E-22 T 23-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 23-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 Gene3D G3DSA:3.40.50.360 4 146 7.4E-40 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 PANTHER PTHR19384 1 148 1.2E-51 T 23-04-2016 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 PANTHER PTHR19384:SF81 1 148 1.2E-51 T 23-04-2016 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 PRINTS PR00369 Flavodoxin signature 5 18 8.2E-6 T 23-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 PRINTS PR00369 Flavodoxin signature 53 64 8.2E-6 T 23-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPYM18_RS03390 c84c87ef3d7eff8a44fccaa6864cf257 149 PRINTS PR00369 Flavodoxin signature 82 92 8.2E-6 T 23-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 SUPERFAMILY SSF53098 61 257 7.89E-66 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 PANTHER PTHR10954 3 256 2.1E-104 T 23-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 PANTHER PTHR10954:SF7 3 256 2.1E-104 T 23-04-2016 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 Hamap MF_00052_B Ribonuclease HII [rnhB]. 72 253 34.261 T 23-04-2016 IPR022898 Ribonuclease HII GO:0004523 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 Gene3D G3DSA:3.30.420.10 72 214 2.9E-46 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04850 0ea419ff9c79c416cf8f4f97a751262b 263 Pfam PF01351 Ribonuclease HII 74 252 8.7E-36 T 23-04-2016 IPR024567 Ribonuclease HII/HIII domain SPYM18_RS08875 2ccbc7acd285979c3867f208e46a25c2 146 Gene3D G3DSA:3.40.630.30 3 136 3.0E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08875 2ccbc7acd285979c3867f208e46a25c2 146 SUPERFAMILY SSF55729 2 138 3.14E-18 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08875 2ccbc7acd285979c3867f208e46a25c2 146 Pfam PF13673 Acetyltransferase (GNAT) domain 42 138 8.5E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 Pfam PF00120 Glutamine synthetase, catalytic domain 107 444 2.6E-135 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 PANTHER PTHR20852:SF7 1 448 1.9E-180 T 23-04-2016 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 23-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 SUPERFAMILY SSF55931 107 445 9.32E-122 T 23-04-2016 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 SMART SM01230 106 358 1.1E-129 T 23-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 5.1E-29 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 PANTHER PTHR20852 1 448 1.9E-180 T 23-04-2016 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 Gene3D G3DSA:3.30.590.10 110 434 6.6E-121 T 23-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 445 9.3E-169 T 23-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 Gene3D G3DSA:3.10.20.70 5 109 7.0E-38 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS08375 32aec91a1c21db0e0a067fb400371ab1 448 SUPERFAMILY SSF54368 4 105 2.88E-30 T 23-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 PANTHER PTHR24220 44 263 3.4E-95 T 23-04-2016 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 PANTHER PTHR24220 9 19 3.4E-95 T 23-04-2016 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 SUPERFAMILY SSF52540 36 243 1.96E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 Gene3D G3DSA:3.40.50.300 4 249 3.9E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 Pfam PF00005 ABC transporter 47 178 3.8E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 SMART SM00382 56 228 4.7E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 PANTHER PTHR24220:SF117 44 263 3.4E-95 T 23-04-2016 SPYM18_RS03665 3981b2a265247b6a86d59d511287a276 401 PANTHER PTHR24220:SF117 9 19 3.4E-95 T 23-04-2016 SPYM18_RS07595 591868a5960659a3a5a63a3dc48d6dcf 132 Pfam PF12691 Minor capsid protein from bacteriophage 4 128 5.3E-43 T 23-04-2016 IPR024411 Minor capsid protein, bacteriophage SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 PANTHER PTHR30345:SF0 1 211 5.1E-37 T 23-04-2016 SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 Pfam PF12408 Ribose-5-phosphate isomerase 164 210 2.9E-20 T 23-04-2016 IPR022133 Ribose-5-phosphate isomerase, C-terminal SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 Pfam PF02502 Ribose/Galactose Isomerase 3 158 2.6E-26 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 Gene3D G3DSA:3.40.1400.10 1 211 7.6E-89 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 PANTHER PTHR30345 1 211 5.1E-37 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS02985 6663e1fb1d4d18c8fd5c3e8bc5c0fe23 213 SUPERFAMILY SSF89623 1 161 8.5E-34 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 169 183 2.1E-24 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 550 2.1E-24 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 320 334 2.1E-24 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 462 472 2.1E-24 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 515 534 2.1E-24 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 68 616 1.5E-185 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 68 405 1.9E-103 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 322 328 - T 23-04-2016 IPR018303 P-type ATPase, phosphorylation site SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 91 595 1.6E-79 T 23-04-2016 IPR001757 P-type ATPase GO:0016021 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF56784 373 613 1.04E-49 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF56784 319 338 1.04E-49 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Gene3D G3DSA:3.40.50.1000 443 578 7.4E-47 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Gene3D G3DSA:3.40.50.1000 294 336 7.4E-47 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Gene3D G3DSA:2.70.150.10 70 220 1.9E-26 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PANTHER PTHR24093 36 592 2.1E-171 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF81653 127 219 6.41E-20 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00941 Cadmium-transporting ATPase signature 185 201 5.7E-8 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00941 Cadmium-transporting ATPase signature 103 123 5.7E-8 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00941 Cadmium-transporting ATPase signature 31 48 5.7E-8 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00941 Cadmium-transporting ATPase signature 48 60 5.7E-8 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PRINTS PR00941 Cadmium-transporting ATPase signature 204 218 5.7E-8 T 23-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Pfam PF00702 haloacid dehalogenase-like hydrolase 316 529 2.4E-43 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 PANTHER PTHR24093:SF317 36 592 2.1E-171 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Pfam PF00122 E1-E2 ATPase 90 310 1.1E-46 T 23-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF81665 220 314 5.23E-14 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF81665 563 589 5.23E-14 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 SUPERFAMILY SSF81665 70 122 5.23E-14 T 23-04-2016 SPYM18_RS06210 f90c352a0e155ac589829afccd8fd64d 620 Gene3D G3DSA:3.40.1110.10 346 442 2.0E-9 T 23-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 SUPERFAMILY SSF55681 114 295 1.06E-104 T 23-04-2016 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 SUPERFAMILY SSF55681 419 578 1.06E-104 T 23-04-2016 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Pfam PF02938 GAD domain 314 400 1.2E-24 T 23-04-2016 IPR029351 GAD domain SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 8.9E-24 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 8.9E-24 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 8.9E-24 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 8.9E-24 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 SUPERFAMILY SSF55261 292 414 2.29E-35 T 23-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Gene3D G3DSA:2.40.50.140 1 108 5.7E-36 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 SUPERFAMILY SSF50249 2 110 6.29E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Gene3D G3DSA:3.30.930.10 134 279 4.8E-111 T 23-04-2016 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Gene3D G3DSA:3.30.930.10 409 579 4.8E-111 T 23-04-2016 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PANTHER PTHR22594 365 566 2.6E-243 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PANTHER PTHR22594 1 300 2.6E-243 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Pfam PF01336 OB-fold nucleic acid binding domain 20 103 9.9E-16 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PANTHER PTHR22594:SF5 365 566 2.6E-243 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 PANTHER PTHR22594:SF5 1 300 2.6E-243 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Gene3D G3DSA:3.30.1360.30 280 408 3.0E-46 T 23-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 558 35.075 T 23-04-2016 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 552 1.5E-105 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09370 a05c02344f520ea11056a57b9ef7486f 582 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 577 1.4E-230 T 23-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF52440 550 668 5.61E-47 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.40.50.20 3 108 2.1E-44 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF56059 128 399 5.13E-106 T 23-04-2016 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.40.50.20 532 655 4.4E-59 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 8.6E-42 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PANTHER PTHR11405 1 1050 0.0 T 23-04-2016 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.30.1490.20 142 200 3.4E-24 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.30.1490.20 679 737 3.1E-28 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SMART SM00851 949 1036 1.0E-18 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF56059 666 926 5.05E-103 T 23-04-2016 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.6E-62 T 23-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1057 13.046 T 23-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Pfam PF02142 MGS-like domain 950 1036 1.2E-14 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1047 0.0 T 23-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.30.470.20 201 398 1.6E-72 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.30.470.20 738 927 2.6E-72 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SMART SM01096 420 540 4.8E-67 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 3.9E-78 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 866 9.3E-40 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 PANTHER PTHR11405:SF5 1 1050 0.0 T 23-04-2016 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF52335 936 1052 4.06E-24 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:3.40.50.1380 931 1051 1.2E-27 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF52440 1 127 2.45E-49 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SMART SM01209 674 837 2.5E-4 T 23-04-2016 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 SUPERFAMILY SSF48108 395 547 1.14E-50 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Gene3D G3DSA:1.10.1030.10 399 531 7.0E-50 T 23-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03850 352605ec5700e8f2056086260018384f 1058 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1058 13.245 T 23-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS01975 19718c85d7ae650b75b576b9bbeabaa9 345 Pfam PF01032 FecCD transport family 29 343 1.9E-83 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS01975 19718c85d7ae650b75b576b9bbeabaa9 345 PANTHER PTHR30472 14 345 5.8E-92 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS01975 19718c85d7ae650b75b576b9bbeabaa9 345 SUPERFAMILY SSF81345 12 343 1.26E-69 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS01975 19718c85d7ae650b75b576b9bbeabaa9 345 PANTHER PTHR30472:SF16 14 345 5.8E-92 T 23-04-2016 SPYM18_RS01975 19718c85d7ae650b75b576b9bbeabaa9 345 Gene3D G3DSA:1.10.3470.10 17 345 1.7E-85 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 7.9E-5 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 7.9E-5 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 PANTHER PTHR30146 1 337 1.5E-84 T 23-04-2016 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 Pfam PF13377 Periplasmic binding protein-like domain 175 334 5.1E-26 T 23-04-2016 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 Gene3D G3DSA:1.10.260.40 2 53 3.1E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 Gene3D G3DSA:3.40.50.2300 54 178 7.7E-29 T 23-04-2016 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 Gene3D G3DSA:3.40.50.2300 179 313 6.1E-28 T 23-04-2016 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 8.4E-19 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 SMART SM00354 1 71 5.0E-31 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 SUPERFAMILY SSF53822 59 328 3.64E-48 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 SUPERFAMILY SSF47413 1 59 3.77E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05700 9959eb96554e0fb5ec7bbd489e4f5cac 339 PANTHER PTHR30146:SF30 1 337 1.5E-84 T 23-04-2016 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PRINTS PR00108 Thymidylate synthase family signature 209 226 3.8E-13 T 23-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PRINTS PR00108 Thymidylate synthase family signature 54 75 3.8E-13 T 23-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PRINTS PR00108 Thymidylate synthase family signature 171 197 3.8E-13 T 23-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PRINTS PR00108 Thymidylate synthase family signature 122 141 3.8E-13 T 23-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 SUPERFAMILY SSF55831 3 271 1.27E-72 T 23-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PANTHER PTHR11548 12 279 2.3E-115 T 23-04-2016 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 Pfam PF00303 Thymidylate synthase 8 278 4.7E-64 T 23-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 PANTHER PTHR11548:SF1 12 279 2.3E-115 T 23-04-2016 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 Gene3D G3DSA:3.30.572.10 4 279 1.5E-64 T 23-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 Hamap MF_00008 Thymidylate synthase [thyA]. 5 279 30.426 T 23-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS04055 4d800952a589243116437a0b7669f87f 279 ProSitePatterns PS00091 Thymidylate synthase active site. 133 162 - T 23-04-2016 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 Gene3D G3DSA:3.30.420.40 1 101 2.5E-34 T 23-04-2016 SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 SUPERFAMILY SSF53067 1 289 8.48E-54 T 23-04-2016 SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 PANTHER PTHR18964:SF131 1 288 4.0E-68 T 23-04-2016 SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 Pfam PF00480 ROK family 4 283 3.9E-45 T 23-04-2016 IPR000600 ROK family SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 Gene3D G3DSA:3.30.420.40 102 291 3.2E-55 T 23-04-2016 SPYM18_RS06900 67229ba94c3472c701f9bd2111985c34 292 PANTHER PTHR18964 1 288 4.0E-68 T 23-04-2016 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 349 372 - T 23-04-2016 IPR020595 MnmG-related, conserved site SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 PANTHER PTHR11806:SF2 9 438 7.3E-239 T 23-04-2016 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 8 443 2.4E-208 T 23-04-2016 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 9 447 35.663 T 23-04-2016 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 Gene3D G3DSA:3.50.50.60 290 330 8.2E-8 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 PANTHER PTHR11806 9 438 7.3E-239 T 23-04-2016 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 Gene3D G3DSA:3.50.50.60 331 385 2.1E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 Gene3D G3DSA:3.50.50.60 11 232 2.1E-12 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 SUPERFAMILY SSF51905 11 376 3.61E-26 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04865 ca7c56f71e4ddad92c69def8cf47d3c0 448 Pfam PF01134 Glucose inhibited division protein A 9 379 6.9E-114 T 23-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 PANTHER PTHR18919:SF95 1 395 5.3E-221 T 23-04-2016 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Pfam PF02803 Thiolase, C-terminal domain 272 392 2.2E-50 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Pfam PF00108 Thiolase, N-terminal domain 4 264 1.7E-103 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Gene3D G3DSA:3.40.47.10 143 193 1.1E-72 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Gene3D G3DSA:3.40.47.10 278 393 1.1E-72 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 392 5.7E-151 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 PANTHER PTHR18919 1 395 5.3E-221 T 23-04-2016 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Gene3D G3DSA:3.40.47.10 194 277 7.0E-74 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 Gene3D G3DSA:3.40.47.10 4 123 7.0E-74 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 SUPERFAMILY SSF53901 272 391 2.98E-44 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 PIRSF PIRSF000429 1 395 1.9E-138 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS07105 00deaf2c35fc82caaf996b8241844fb6 395 SUPERFAMILY SSF53901 4 271 3.53E-87 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 SUPERFAMILY SSF54211 191 327 2.81E-35 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 SMART SM01340 209 327 1.4E-49 T 23-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 119 3.8E-11 T 23-04-2016 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 644 27.296 T 23-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 1.5E-98 T 23-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 SUPERFAMILY SSF118116 458 646 7.98E-51 T 23-04-2016 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Pfam PF08676 MutL C terminal dimerisation domain 462 604 4.9E-38 T 23-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 SMART SM00853 462 604 5.6E-44 T 23-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 23-04-2016 IPR014762 DNA mismatch repair, conserved site SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 SUPERFAMILY SSF55874 2 214 2.62E-53 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 PANTHER PTHR10073 4 660 7.6E-159 T 23-04-2016 SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Gene3D G3DSA:3.30.230.10 204 326 3.0E-36 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Gene3D G3DSA:3.30.565.10 4 203 4.7E-73 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS09325 511ff225d5ff0ae34969a3cf3b4d2bf2 660 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 326 1.2E-34 T 23-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 ProSitePatterns PS01348 MraY family signature 2. 167 178 - T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 334 21.058 T 23-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 333 3.8E-73 T 23-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 PANTHER PTHR22926 1 335 4.0E-121 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 PANTHER PTHR22926:SF5 1 335 4.0E-121 T 23-04-2016 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 Pfam PF00953 Glycosyl transferase family 4 84 247 2.5E-37 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07210 b5b9ec9541baf49f1566abd8d4d45145 336 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 5.2E-5 T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 Gene3D G3DSA:2.20.150.10 9 35 5.2E-5 T 23-04-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 5.7E-113 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 PANTHER PTHR10584:SF170 1 279 1.3E-110 T 23-04-2016 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 PANTHER PTHR10584 1 279 1.3E-110 T 23-04-2016 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 9.4E-115 T 23-04-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 23-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 SUPERFAMILY SSF53613 1 282 2.03E-69 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 PIRSF PIRSF000535 1 303 1.3E-86 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 Pfam PF00294 pfkB family carbohydrate kinase 11 280 8.8E-53 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB SPYM18_RS03935 e62eb2da5c1cfe5c68f2fec91c8c67b7 303 Gene3D G3DSA:3.40.1190.20 36 302 3.4E-82 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS04275 cbe04c89e0364f4e1a93c616829eff4c 228 PIRSF PIRSF018637 3 227 2.2E-72 T 23-04-2016 IPR006901 tRNA methyltransferase TrmK GO:0016429 SPYM18_RS04275 cbe04c89e0364f4e1a93c616829eff4c 228 SUPERFAMILY SSF53335 12 104 1.48E-7 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS04275 cbe04c89e0364f4e1a93c616829eff4c 228 PANTHER PTHR38451 1 227 4.1E-76 T 23-04-2016 SPYM18_RS04275 cbe04c89e0364f4e1a93c616829eff4c 228 Gene3D G3DSA:3.40.50.150 9 154 1.1E-6 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS04275 cbe04c89e0364f4e1a93c616829eff4c 228 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 22 222 9.7E-82 T 23-04-2016 IPR006901 tRNA methyltransferase TrmK GO:0016429 SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 PANTHER PTHR34382 1 106 4.0E-39 T 23-04-2016 SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 Gene3D G3DSA:1.20.58.80 8 103 1.5E-35 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 SUPERFAMILY SSF46973 7 101 6.67E-33 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 PIRSF PIRSF000699 1 106 1.4E-35 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 8 101 1.7E-32 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09055 625cb87fa7c6520e3adba3464360fe2f 106 PANTHER PTHR34382:SF2 1 106 4.0E-39 T 23-04-2016 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 PANTHER PTHR33375:SF3 3 258 9.5E-93 T 23-04-2016 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 Gene3D G3DSA:1.10.10.10 96 144 1.3E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 SUPERFAMILY SSF110849 7 99 2.88E-25 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 Pfam PF02195 ParB-like nuclease domain 9 96 8.4E-23 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 6 179 4.7E-54 T 23-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 Gene3D G3DSA:3.90.1530.10 6 95 3.5E-34 T 23-04-2016 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 SUPERFAMILY SSF109709 90 197 1.28E-34 T 23-04-2016 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 PANTHER PTHR33375 3 258 9.5E-93 T 23-04-2016 SPYM18_RS09645 a39edf4ad0faf10d6e023262e8ce5b72 258 SMART SM00470 7 97 1.2E-31 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS00680 02e0cafa2694cf3060dbd0fe0ebae6cc 317 PIRSF PIRSF026567 1 317 2.2E-120 T 23-04-2016 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted SPYM18_RS00680 02e0cafa2694cf3060dbd0fe0ebae6cc 317 Pfam PF02384 N-6 DNA Methylase 68 288 1.1E-9 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPYM18_RS00680 02e0cafa2694cf3060dbd0fe0ebae6cc 317 Gene3D G3DSA:3.40.50.150 97 310 6.4E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS00680 02e0cafa2694cf3060dbd0fe0ebae6cc 317 PANTHER PTHR41313 2 317 6.2E-103 T 23-04-2016 SPYM18_RS00680 02e0cafa2694cf3060dbd0fe0ebae6cc 317 SUPERFAMILY SSF53335 48 306 7.63E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 SUPERFAMILY SSF81336 71 229 6.93E-36 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PRINTS PR00123 ATP synthase A subunit signature 79 95 3.6E-20 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PRINTS PR00123 ATP synthase A subunit signature 216 231 3.6E-20 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PRINTS PR00123 ATP synthase A subunit signature 147 162 3.6E-20 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PRINTS PR00123 ATP synthase A subunit signature 163 185 3.6E-20 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 16 232 9.9E-42 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PANTHER PTHR11410:SF7 14 238 5.5E-59 T 23-04-2016 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 PANTHER PTHR11410 14 238 5.5E-59 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 ProSitePatterns PS00449 ATP synthase a subunit signature. 166 175 - T 23-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 Gene3D G3DSA:1.20.120.220 73 235 1.4E-37 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 236 13.24 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS03515 0820ae00b1b5675b58d384ce5a9f2eed 238 Pfam PF00119 ATP synthase A chain 23 229 3.0E-48 T 23-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 PANTHER PTHR21237 21 188 2.6E-44 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 SUPERFAMILY SSF51064 142 189 8.11E-13 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 PRINTS PR00773 GrpE protein signature 64 80 6.23E-24 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 PRINTS PR00773 GrpE protein signature 92 107 6.23E-24 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 PRINTS PR00773 GrpE protein signature 141 156 6.23E-24 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 PRINTS PR00773 GrpE protein signature 169 188 6.23E-24 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 Gene3D G3DSA:3.90.20.20 42 133 8.3E-25 T 23-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 SUPERFAMILY SSF58014 46 135 1.96E-21 T 23-04-2016 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 Pfam PF01025 GrpE 32 189 1.9E-43 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 Gene3D G3DSA:2.30.22.10 140 189 3.9E-20 T 23-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 Hamap MF_01151 Protein GrpE [grpE]. 21 190 18.545 T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS07920 ce0aa4e809711331bb42af133fdd1ce3 190 ProSitePatterns PS01071 grpE protein signature. 144 188 - T 23-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 PANTHER PTHR23105 21 229 1.2E-77 T 23-04-2016 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 5.7E-51 T 23-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 1.1E-102 T 23-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 SUPERFAMILY SSF56808 6 227 1.31E-82 T 23-04-2016 IPR023674 Ribosomal protein L1-like SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 PANTHER PTHR23105:SF5 21 229 1.2E-77 T 23-04-2016 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 Gene3D G3DSA:3.40.50.790 69 159 7.0E-44 T 23-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.343 T 23-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 PIRSF PIRSF002155 1 227 9.7E-78 T 23-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 23-04-2016 IPR023673 Ribosomal protein L1, conserved site SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 Gene3D G3DSA:3.30.190.20 161 227 9.6E-44 T 23-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 SPYM18_RS02205 0477bf5e37f2db54fc34e1673d67c6dd 229 Gene3D G3DSA:3.30.190.20 17 68 9.6E-44 T 23-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 SPYM18_RS09585 ad8e78391613530fe2cd1d06b5175368 287 SUPERFAMILY SSF103481 37 125 9.68E-11 T 23-04-2016 SPYM18_RS09585 ad8e78391613530fe2cd1d06b5175368 287 PANTHER PTHR16119:SF19 4 287 2.6E-68 T 23-04-2016 SPYM18_RS09585 ad8e78391613530fe2cd1d06b5175368 287 PANTHER PTHR16119 4 287 2.6E-68 T 23-04-2016 SPYM18_RS09585 ad8e78391613530fe2cd1d06b5175368 287 TIGRFAM TIGR00776 RhaT: RhaT L-rhamnose-proton symporter family protein 3 286 1.9E-106 T 23-04-2016 IPR004673 L-rhamnose-proton symport, RhaT GO:0008645|GO:0015153|GO:0016021 SPYM18_RS09585 ad8e78391613530fe2cd1d06b5175368 287 Pfam PF06800 Sugar transport protein 6 285 2.4E-111 T 23-04-2016 IPR010651 Sugar transport protein GO:0015144|GO:0016021|GO:0034219 SPYM18_RS01320 25b4dc7fa4768284febee71be737b9a0 159 PANTHER PTHR10093 1 140 1.4E-40 T 23-04-2016 SPYM18_RS01320 25b4dc7fa4768284febee71be737b9a0 159 SUPERFAMILY SSF82649 2 141 1.7E-48 T 23-04-2016 SPYM18_RS01320 25b4dc7fa4768284febee71be737b9a0 159 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 140 6.2E-54 T 23-04-2016 SPYM18_RS01320 25b4dc7fa4768284febee71be737b9a0 159 Gene3D G3DSA:3.90.1010.10 9 146 5.1E-42 T 23-04-2016 SPYM18_RS01320 25b4dc7fa4768284febee71be737b9a0 159 Pfam PF01592 NifU-like N terminal domain 10 127 2.3E-27 T 23-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 Pfam PF00005 ABC transporter 23 165 7.5E-37 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 Gene3D G3DSA:3.40.50.300 3 238 6.1E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 291 7.5E-108 T 23-04-2016 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 SMART SM00382 32 215 1.0E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 PANTHER PTHR24220 7 381 1.7E-177 T 23-04-2016 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 SUPERFAMILY SSF50331 240 345 3.68E-11 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 SUPERFAMILY SSF52540 5 248 1.4E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 Pfam PF08402 TOBE domain 276 344 5.5E-5 T 23-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 SPYM18_RS04585 a6c483fa2b546bf2f201bce205e38b3c 384 PANTHER PTHR24220:SF150 7 381 1.7E-177 T 23-04-2016 SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 Gene3D G3DSA:1.10.3210.10 3 192 1.4E-61 T 23-04-2016 IPR006674 HD domain SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 Pfam PF01966 HD domain 26 138 3.0E-12 T 23-04-2016 IPR006674 HD domain SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 PANTHER PTHR35795 3 190 8.2E-65 T 23-04-2016 SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 SUPERFAMILY SSF109604 4 189 3.14E-31 T 23-04-2016 SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 20 188 5.5E-48 T 23-04-2016 IPR005249 Conserved hypothetical protein CHP00488 SPYM18_RS01420 dbc37924ff01307028063fe881a51d4e 197 SMART SM00471 22 149 2.5E-5 T 23-04-2016 IPR003607 HD/PDEase domain SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 SUPERFAMILY SSF55594 1 83 4.06E-28 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 Pfam PF00381 PTS HPr component phosphorylation site 3 81 2.1E-29 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.4E-27 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.4E-27 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.4E-27 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 PANTHER PTHR33705 1 84 6.8E-36 T 23-04-2016 SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 Gene3D G3DSA:3.30.1340.10 1 83 8.0E-34 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 2.5E-32 T 23-04-2016 IPR000032 Phosphocarrier HPr protein-like SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 PANTHER PTHR33705:SF2 1 84 6.8E-36 T 23-04-2016 SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 23-04-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site SPYM18_RS05995 a65391e4718b1a5ded0f361653c4172f 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 23-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 Pfam PF02971 Formiminotransferase domain 182 285 2.9E-26 T 23-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 TIGRFAM TIGR02024 FtcD: glutamate formiminotransferase 1 297 2.0E-131 T 23-04-2016 IPR004227 Formiminotransferase catalytic domain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 Gene3D G3DSA:3.30.70.670 182 297 7.3E-48 T 23-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 Pfam PF07837 Formiminotransferase domain, N-terminal subdomain 4 179 5.3E-72 T 23-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 PANTHER PTHR12234 1 286 1.8E-136 T 23-04-2016 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 SUPERFAMILY SSF55116 3 180 5.62E-70 T 23-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 SUPERFAMILY SSF55116 181 293 1.33E-45 T 23-04-2016 IPR022384 Formiminotransferase subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 SMART SM01222 3 180 2.1E-113 T 23-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 Gene3D G3DSA:3.30.990.10 3 180 7.4E-75 T 23-04-2016 IPR012886 Formiminotransferase, N-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 PANTHER PTHR12234:SF0 1 286 1.8E-136 T 23-04-2016 SPYM18_RS09170 8ccb9564c1a4b517a54f8ee5d11c024e 299 SMART SM01221 181 296 7.3E-77 T 23-04-2016 IPR013802 Formiminotransferase, C-terminal subdomain GO:0005542|GO:0008152|GO:0016740 KEGG: 00340+2.1.2.5|KEGG: 00670+2.1.2.5|MetaCyc: PWY-5030|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 2.3E-105 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.091 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 23-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 Pfam PF00318 Ribosomal protein S2 9 224 6.3E-97 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 37 46 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 196 210 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 6 24 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 87 104 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 158 175 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PRINTS PR00395 Ribosomal protein S2 signature 175 186 7.8E-42 T 23-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 Gene3D G3DSA:3.40.50.10490 158 245 5.9E-69 T 23-04-2016 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 Gene3D G3DSA:3.40.50.10490 23 99 5.9E-69 T 23-04-2016 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 Gene3D G3DSA:1.10.287.610 100 152 5.7E-26 T 23-04-2016 SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 SUPERFAMILY SSF52313 6 232 6.41E-96 T 23-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain SPYM18_RS09210 e0c1e05f8601ca19b28c59442860be38 255 PANTHER PTHR12534 1 226 5.4E-121 T 23-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 SPYM18_RS07750 d6d84dce19e4775de53e75b39024db47 118 Gene3D G3DSA:1.10.10.10 23 70 2.2E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07750 d6d84dce19e4775de53e75b39024db47 118 Pfam PF08279 HTH domain 24 66 6.8E-5 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 Pfam PF00005 ABC transporter 17 168 1.3E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 Gene3D G3DSA:3.40.50.300 1 239 7.3E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 SMART SM00382 26 216 7.6E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 PANTHER PTHR24220 3 246 3.1E-113 T 23-04-2016 SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 SUPERFAMILY SSF52540 1 238 1.39E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 PANTHER PTHR24220:SF550 3 246 3.1E-113 T 23-04-2016 SPYM18_RS07195 448e30299285e9765c778e073d1f85d8 247 PIRSF PIRSF039085 1 244 3.7E-95 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 Gene3D G3DSA:1.10.1900.20 55 117 1.7E-31 T 23-04-2016 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 Pfam PF00453 Ribosomal protein L20 3 109 7.8E-49 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 PANTHER PTHR10986 2 117 6.3E-64 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 1.0E-13 T 23-04-2016 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 PANTHER PTHR10986:SF12 2 117 6.3E-64 T 23-04-2016 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 SUPERFAMILY SSF74731 3 116 5.36E-49 T 23-04-2016 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.315 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.1E-50 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 7.6E-41 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 7.6E-41 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS03735 dc97795339595225ea7c9581cb4521f7 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 7.6E-41 T 23-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 SUPERFAMILY SSF144010 5 235 3.27E-55 T 23-04-2016 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 227 5.5E-50 T 23-04-2016 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199|UniPathway: UPA00071 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 PANTHER PTHR21712:SF30 35 244 4.9E-28 T 23-04-2016 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 Gene3D G3DSA:3.90.1660.10 56 141 1.4E-11 T 23-04-2016 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 PANTHER PTHR21712 35 244 4.9E-28 T 23-04-2016 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 Gene3D G3DSA:3.30.1330.100 142 234 3.3E-45 T 23-04-2016 SPYM18_RS02610 51b28934eb0ab95f1d3c2b88a1ab0d2b 244 Gene3D G3DSA:3.30.1330.100 2 54 3.3E-45 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Gene3D G3DSA:2.60.120.260 20 164 6.5E-36 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066 27 394 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066 500 541 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066 567 682 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066 410 479 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PRINTS PR00132 Glycosyl hydrolase family 2 signature 428 443 1.13E-8 T 23-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PRINTS PR00132 Glycosyl hydrolase family 2 signature 306 320 1.13E-8 T 23-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PRINTS PR00132 Glycosyl hydrolase family 2 signature 106 121 1.13E-8 T 23-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PRINTS PR00132 Glycosyl hydrolase family 2 signature 337 355 1.13E-8 T 23-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Gene3D G3DSA:3.20.20.80 298 644 2.3E-67 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 SUPERFAMILY SSF49785 18 174 8.87E-39 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Pfam PF16355 Domain of unknown function (DUF4982) 669 751 7.6E-11 T 23-04-2016 IPR032311 Domain of unknown function DUF4982 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 SUPERFAMILY SSF49303 230 294 1.61E-10 T 23-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Pfam PF00703 Glycosyl hydrolases family 2 198 294 1.4E-8 T 23-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 SUPERFAMILY SSF51445 299 643 1.26E-54 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 302 496 4.3E-26 T 23-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Gene3D G3DSA:2.60.40.1560 665 751 4.8E-6 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066:SF71 27 394 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066:SF71 500 541 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066:SF71 567 682 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 PANTHER PTHR10066:SF71 410 479 4.3E-120 T 23-04-2016 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Gene3D G3DSA:2.60.40.320 165 295 3.5E-18 T 23-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 SPYM18_RS06865 c68ee750f026b6e70ed2964effbf337d 1138 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 27 174 1.0E-18 T 23-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 SUPERFAMILY SSF53271 5 167 8.95E-50 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 Gene3D G3DSA:3.40.50.2020 2 170 2.7E-63 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.114 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 PANTHER PTHR11776:SF0 1 171 1.1E-74 T 23-04-2016 SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 169 5.1E-66 T 23-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 Pfam PF00156 Phosphoribosyl transferase domain 32 167 4.1E-17 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS04260 5024f961c57f1d8e21c041c8cdd612b4 172 PANTHER PTHR11776 1 171 1.1E-74 T 23-04-2016 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Pfam PF03461 TRCF domain 1013 1097 2.8E-24 T 23-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF143517 998 1156 6.54E-34 T 23-04-2016 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF52540 18 359 1.03E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SMART SM00490 834 918 1.7E-17 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SMART SM00982 1012 1112 1.5E-33 T 23-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF52540 790 995 1.42E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Gene3D G3DSA:3.40.50.300 809 964 2.2E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 PANTHER PTHR14025 397 1157 0.0 T 23-04-2016 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Pfam PF00271 Helicase conserved C-terminal domain 814 917 3.2E-16 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 156 1079 0.0 T 23-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF141259 478 556 5.75E-23 T 23-04-2016 IPR003711 CarD-like/TRCF domain SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Gene3D G3DSA:3.30.2060.10 140 218 1.5E-17 T 23-04-2016 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF52540 367 477 1.55E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 PANTHER PTHR14025:SF21 397 1157 0.0 T 23-04-2016 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SUPERFAMILY SSF52540 547 791 3.4E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Pfam PF00270 DEAD/DEAH box helicase 614 772 2.2E-19 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SMART SM01058 487 584 3.5E-43 T 23-04-2016 IPR003711 CarD-like/TRCF domain SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Gene3D G3DSA:3.40.50.300 595 794 1.3E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1119 28.56 T 23-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 Pfam PF02559 CarD-like/TRCF domain 488 583 3.0E-26 T 23-04-2016 IPR003711 CarD-like/TRCF domain SPYM18_RS00030 ef1481f4bcc61f3b449aa013b4c3e302 1167 SMART SM00487 608 798 1.0E-36 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 SUPERFAMILY SSF55307 205 319 3.43E-41 T 23-04-2016 IPR008280 Tubulin/FtsZ, C-terminal SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 370 37.676 T 23-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 Gene3D G3DSA:3.40.50.1440 15 215 5.8E-92 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 5.5E-41 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PANTHER PTHR30314:SF3 1 363 6.8E-184 T 23-04-2016 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 SMART SM00865 208 325 2.1E-48 T 23-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 23-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PRINTS PR00423 Cell division protein FtsZ signature 99 119 2.2E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PRINTS PR00423 Cell division protein FtsZ signature 190 212 2.2E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PRINTS PR00423 Cell division protein FtsZ signature 127 148 2.2E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PRINTS PR00423 Cell division protein FtsZ signature 213 234 2.2E-51 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 Pfam PF12327 FtsZ family, C-terminal domain 223 316 8.8E-29 T 23-04-2016 IPR024757 Cell division protein FtsZ, C-terminal SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 PANTHER PTHR30314 1 363 6.8E-184 T 23-04-2016 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 329 1.0E-125 T 23-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 SMART SM00864 14 206 1.6E-110 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 Gene3D G3DSA:3.30.1330.20 216 323 8.1E-45 T 23-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain SPYM18_RS06620 4ef67143e7f0cb5f55e3cd0b1fe1c235 439 SUPERFAMILY SSF52490 15 209 7.72E-68 T 23-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 SPYM18_RS00765 fb1e665d93c3855e406fd2ec609773af 241 Gene3D G3DSA:2.40.260.10 19 238 3.9E-60 T 23-04-2016 IPR023365 Sortase domain SPYM18_RS00765 fb1e665d93c3855e406fd2ec609773af 241 PIRSF PIRSF030150 1 241 1.4E-89 T 23-04-2016 IPR015986 Sortase B, Firmicutes SPYM18_RS00765 fb1e665d93c3855e406fd2ec609773af 241 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 7 235 4.0E-85 T 23-04-2016 IPR009835 Sortase B family SPYM18_RS00765 fb1e665d93c3855e406fd2ec609773af 241 Pfam PF04203 Sortase family 73 238 3.2E-16 T 23-04-2016 IPR005754 Sortase family SPYM18_RS00765 fb1e665d93c3855e406fd2ec609773af 241 SUPERFAMILY SSF63817 12 239 1.86E-69 T 23-04-2016 IPR023365 Sortase domain SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 PANTHER PTHR10357 441 536 9.6E-272 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 PANTHER PTHR10357 5 412 9.6E-272 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 SUPERFAMILY SSF51445 5 463 1.91E-138 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 SMART SM00642 11 407 5.6E-131 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Gene3D G3DSA:3.20.20.80 167 464 3.2E-113 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Gene3D G3DSA:3.20.20.80 5 101 3.2E-113 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 SUPERFAMILY SSF51011 466 539 2.64E-15 T 23-04-2016 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 538 1.1E-265 T 23-04-2016 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 PANTHER PTHR10357:SF170 441 536 9.6E-272 T 23-04-2016 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 PANTHER PTHR10357:SF170 5 412 9.6E-272 T 23-04-2016 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Gene3D G3DSA:2.60.40.1180 467 539 8.3E-18 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Pfam PF00128 Alpha amylase, catalytic domain 26 364 1.9E-102 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Gene3D G3DSA:3.90.400.10 102 163 2.4E-25 T 23-04-2016 SPYM18_RS09225 f511246fb34be8ce1d56420562cff148 542 Pfam PF11941 Domain of unknown function (DUF3459) 449 519 7.8E-5 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 448 39.971 T 23-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 SUPERFAMILY SSF50249 12 113 1.71E-19 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 9 447 1.3E-142 T 23-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 Gene3D G3DSA:2.40.50.140 10 112 4.5E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PANTHER PTHR22594:SF16 4 448 4.8E-188 T 23-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 Pfam PF01336 OB-fold nucleic acid binding domain 19 106 3.3E-13 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 442 2.7E-80 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 Gene3D G3DSA:3.30.930.10 113 447 2.5E-107 T 23-04-2016 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 9.0E-15 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 403 417 9.0E-15 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 9.0E-15 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 363 379 9.0E-15 T 23-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 PANTHER PTHR22594 4 448 4.8E-188 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS03045 73bc21ef04a94f310c66db1972db206d 448 SUPERFAMILY SSF55681 121 442 8.5E-90 T 23-04-2016 SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 PANTHER PTHR11086 1 140 4.0E-49 T 23-04-2016 IPR015517 Deoxycytidylate deaminase-related SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 Gene3D G3DSA:3.40.140.10 6 139 4.7E-41 T 23-04-2016 SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 116 6.7E-27 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 71 106 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 SUPERFAMILY SSF53927 9 143 1.13E-38 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 SPYM18_RS08140 37b26df5bb23911478fa6006c7adac3d 153 PIRSF PIRSF006019 1 150 5.3E-54 T 23-04-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Gene3D G3DSA:3.40.50.980 156 323 1.5E-35 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Gene3D G3DSA:3.30.300.30 402 509 3.0E-25 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 23-04-2016 IPR020845 AMP-binding, conserved site SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 499 1.0E-8 T 23-04-2016 IPR025110 AMP-binding enzyme C-terminal domain SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 511 275.885 T 23-04-2016 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 SUPERFAMILY SSF56801 6 511 4.97E-116 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 4 510 9.2E-225 T 23-04-2016 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Pfam PF00501 AMP-binding enzyme 10 407 1.5E-77 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Gene3D G3DSA:2.30.38.10 324 394 5.7E-21 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 PANTHER PTHR24095 4 499 7.7E-151 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 Gene3D G3DSA:3.40.50.980 4 155 1.3E-30 T 23-04-2016 SPYM18_RS05750 2c242ceacbdda9232e4eaef5f0e45222 512 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 30 431 8.4E-102 T 23-04-2016 IPR010071 Amino acid adenylation domain SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 PANTHER PTHR22573:SF56 4 180 1.6E-77 T 23-04-2016 SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 PANTHER PTHR22573 4 180 1.6E-77 T 23-04-2016 SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 4.3E-64 T 23-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 SUPERFAMILY SSF53271 5 178 4.72E-58 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 Pfam PF00156 Phosphoribosyl transferase domain 10 160 1.9E-24 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS00055 dd3a6ff83e02414a99c14f626731c17c 180 Gene3D G3DSA:3.40.50.2020 2 179 5.3E-81 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 406 426 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 208 227 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 86 108 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 180 198 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 303 321 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PRINTS PR00175 Sodium/alanine symporter signature 347 369 6.5E-55 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 437 9.2E-158 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PANTHER PTHR30330 1 440 1.3E-209 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 PANTHER PTHR30330:SF3 1 440 1.3E-209 T 23-04-2016 SPYM18_RS05275 e76fcbc59eaed088da5d6bf8c96d89b3 440 Pfam PF01235 Sodium:alanine symporter family 49 438 7.3E-146 T 23-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 PANTHER PTHR31760:SF0 8 237 1.5E-83 T 23-04-2016 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 195 2.5E-49 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 PANTHER PTHR31760 8 237 1.5E-83 T 23-04-2016 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 SUPERFAMILY SSF53335 2 237 7.98E-47 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 215 27.64 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 PIRSF PIRSF003078 2 220 3.3E-53 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 Gene3D G3DSA:3.40.50.150 3 237 1.5E-75 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01485 0e6c7ea10ca5afc91a1ba4886aaf0ec6 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 215 1.5E-49 T 23-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 SPYM18_RS08440 c708e435f2c4e173bd495b5bfa96e584 191 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 94 1.3E-30 T 23-04-2016 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 SPYM18_RS08440 c708e435f2c4e173bd495b5bfa96e584 191 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 83 7.1E-9 T 23-04-2016 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 SPYM18_RS08440 c708e435f2c4e173bd495b5bfa96e584 191 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 188 15.856 T 23-04-2016 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 SPYM18_RS08440 c708e435f2c4e173bd495b5bfa96e584 191 PANTHER PTHR41322 2 188 4.5E-49 T 23-04-2016 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 PANTHER PTHR11895:SF7 2 481 7.6E-214 T 23-04-2016 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 SUPERFAMILY SSF75304 1 481 4.45E-153 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 PANTHER PTHR11895 2 481 7.6E-214 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 ProSitePatterns PS00571 Amidases signature. 150 181 - T 23-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 Gene3D G3DSA:3.90.1300.10 3 482 3.4E-166 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 88.685 T 23-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 Pfam PF01425 Amidase 24 463 9.1E-145 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS07960 2bb8e9061eb2719f9d9ec9d57e6a2858 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 474 4.4E-182 T 23-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 SUPERFAMILY SSF53822 49 305 3.53E-17 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 Gene3D G3DSA:3.40.190.10 3 39 2.4E-4 T 23-04-2016 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 Pfam PF02608 Basic membrane protein 38 349 3.1E-72 T 23-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 PANTHER PTHR34296:SF2 1 350 9.1E-125 T 23-04-2016 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 Gene3D G3DSA:3.40.50.2300 40 168 4.6E-50 T 23-04-2016 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 Gene3D G3DSA:3.40.50.2300 169 243 6.3E-12 T 23-04-2016 SPYM18_RS05105 fa31d3af06fdb623e24234f9861a9eaf 350 PANTHER PTHR34296 1 350 9.1E-125 T 23-04-2016 SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 SUPERFAMILY SSF53062 4 121 1.44E-31 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 Pfam PF03610 PTS system fructose IIA component 5 113 3.1E-24 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 PANTHER PTHR38594 2 122 4.0E-30 T 23-04-2016 SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 5 119 8.3E-36 T 23-04-2016 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 Gene3D G3DSA:3.40.50.510 4 122 7.5E-39 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02540 03b425afa32a1106879c47ea325612dc 124 PANTHER PTHR38594:SF1 2 122 4.0E-30 T 23-04-2016 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 Gene3D G3DSA:3.40.50.150 1 178 1.2E-57 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 177 1.7E-48 T 23-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 PANTHER PTHR18895:SF60 14 178 4.7E-40 T 23-04-2016 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 PIRSF PIRSF004553 1 179 6.4E-53 T 23-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 Pfam PF03602 Conserved hypothetical protein 95 1 177 1.2E-62 T 23-04-2016 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 PANTHER PTHR18895 14 178 4.7E-40 T 23-04-2016 SPYM18_RS06705 f91cd5cb8c4fd9cb08a947e8666972f9 179 SUPERFAMILY SSF53335 1 178 5.06E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06665 1b5b69937e4b6a92d36503eda062c3fc 67 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 60 8.8E-32 T 23-04-2016 IPR009256 Protein of unknown function DUF910 SPYM18_RS06665 1b5b69937e4b6a92d36503eda062c3fc 67 PANTHER PTHR41311 1 66 2.3E-20 T 23-04-2016 SPYM18_RS06665 1b5b69937e4b6a92d36503eda062c3fc 67 SUPERFAMILY SSF158379 1 62 1.31E-25 T 23-04-2016 IPR023164 YqgQ-like domain SPYM18_RS06665 1b5b69937e4b6a92d36503eda062c3fc 67 Gene3D G3DSA:1.10.287.760 1 66 3.7E-35 T 23-04-2016 IPR023164 YqgQ-like domain SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 PANTHER PTHR23083:SF412 2 415 1.7E-45 T 23-04-2016 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 SUPERFAMILY SSF48452 128 409 4.17E-17 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 SMART SM00028 167 200 2.1E-4 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 Pfam PF13181 Tetratricopeptide repeat 168 197 1.5E-6 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 PANTHER PTHR23083 2 415 1.7E-45 T 23-04-2016 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 SUPERFAMILY SSF48452 12 155 5.42E-10 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 Gene3D G3DSA:1.25.40.10 11 182 5.4E-18 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS04315 6f5bfe5d84dbc54e74f8fb9b38cbbc79 415 Gene3D G3DSA:1.25.40.10 183 388 1.6E-25 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 6.1E-100 T 23-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 Gene3D G3DSA:3.40.366.10 2 120 9.0E-70 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 Gene3D G3DSA:3.40.366.10 195 295 9.0E-70 T 23-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 SUPERFAMILY SSF55048 127 195 6.15E-17 T 23-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 297 2.6E-45 T 23-04-2016 IPR020801 Polyketide synthase, acyl transferase domain SPYM18_RS07880 4657be993408a06869969295db9703cb 312 PANTHER PTHR10982 1 305 1.4E-128 T 23-04-2016 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 SUPERFAMILY SSF52151 188 303 5.75E-72 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 SUPERFAMILY SSF52151 4 120 5.75E-72 T 23-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 Gene3D G3DSA:3.30.70.250 124 194 5.9E-26 T 23-04-2016 SPYM18_RS07880 4657be993408a06869969295db9703cb 312 Pfam PF00698 Acyl transferase domain 6 284 4.1E-36 T 23-04-2016 IPR014043 Acyl transferase SPYM18_RS07880 4657be993408a06869969295db9703cb 312 PIRSF PIRSF000446 1 306 3.2E-98 T 23-04-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 Gene3D G3DSA:3.40.50.10330 37 128 4.8E-19 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 Pfam PF01513 ATP-NAD kinase 47 224 1.6E-20 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 Gene3D G3DSA:2.60.200.30 129 245 3.7E-29 T 23-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 SUPERFAMILY SSF111331 37 272 2.09E-57 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 Hamap MF_00361 NAD kinase [nadK]. 11 274 23.871 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS04690 7c9597f81bf1ebd2955de5d409203ce4 278 PANTHER PTHR20275 45 270 2.0E-51 T 23-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 4 158 34.857 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PIRSF PIRSF006160 4 160 1.9E-62 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 8 26 4.5E-33 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 76 94 4.5E-33 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 120 139 4.5E-33 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 52 70 4.5E-33 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 31 49 4.5E-33 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 Gene3D G3DSA:3.30.1360.80 7 159 4.7E-65 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 11 153 6.0E-81 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 7 151 2.8E-52 T 23-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 SUPERFAMILY SSF63411 7 158 7.6E-60 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPYM18_RS07130 74f0993523c9fd55be297dafadd9de91 160 PANTHER PTHR35799 5 160 6.4E-83 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 PANTHER PTHR11014 240 441 2.7E-47 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 PANTHER PTHR11014 1 188 2.7E-47 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 Gene3D G3DSA:3.40.630.10 359 442 7.1E-58 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 Gene3D G3DSA:3.40.630.10 8 184 7.1E-58 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 SUPERFAMILY SSF53187 360 441 4.29E-57 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 SUPERFAMILY SSF53187 8 184 4.29E-57 T 23-04-2016 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 SUPERFAMILY SSF55031 184 356 9.94E-33 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 Pfam PF01546 Peptidase family M20/M25/M40 81 439 8.3E-28 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 Gene3D G3DSA:3.30.70.360 263 353 7.4E-14 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 438 2.6E-129 T 23-04-2016 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 KEGG: 00480+3.4.13.- SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 114 152 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPYM18_RS06720 7a9ec4fa557c1c988d1e33293b6e2f61 443 Gene3D G3DSA:3.30.70.360 200 262 3.6E-7 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 PANTHER PTHR21109 1 56 2.5E-22 T 23-04-2016 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 23-04-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 1.0E-21 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 22.381 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 Pfam PF01165 Ribosomal protein S21 5 56 3.8E-21 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 7.0E-9 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.4E-15 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.4E-15 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.4E-15 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03620 ea869bffe0f63ddc7b6b2a6f3bdf42b6 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.4E-15 T 23-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 SUPERFAMILY SSF56053 1 82 4.71E-26 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PIRSF PIRSF002162 1 177 3.4E-49 T 23-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 Pfam PF00347 Ribosomal protein L6 91 164 7.6E-19 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 Pfam PF00347 Ribosomal protein L6 12 82 1.2E-19 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 Gene3D G3DSA:3.90.930.12 83 177 8.5E-37 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 SUPERFAMILY SSF56053 83 177 1.44E-34 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PANTHER PTHR11655:SF14 1 178 2.1E-84 T 23-04-2016 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PANTHER PTHR11655 1 178 2.1E-84 T 23-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 23-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.457 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.5E-28 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.5E-28 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.5E-28 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 9.4E-72 T 23-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS00445 836e26cab44b059179f1746be7d0df26 178 Gene3D G3DSA:3.90.930.12 2 82 1.9E-30 T 23-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PRINTS PR00070 Dihydrofolate reductase signature 43 54 1.8E-9 T 23-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PRINTS PR00070 Dihydrofolate reductase signature 16 26 1.8E-9 T 23-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PRINTS PR00070 Dihydrofolate reductase signature 96 110 1.8E-9 T 23-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PRINTS PR00070 Dihydrofolate reductase signature 30 38 1.8E-9 T 23-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 Gene3D G3DSA:3.40.430.10 4 163 2.3E-44 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 SUPERFAMILY SSF53597 2 162 9.69E-46 T 23-04-2016 IPR024072 Dihydrofolate reductase-like domain SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 23-04-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 Pfam PF00186 Dihydrofolate reductase 5 162 2.3E-46 T 23-04-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PANTHER PTHR22778 1 163 4.9E-23 T 23-04-2016 SPYM18_RS04060 8efd9c038a19bd6f682bed8b3c481775 165 PANTHER PTHR22778:SF16 1 163 4.9E-23 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 SUPERFAMILY SSF53807 16 308 8.34E-86 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 Gene3D G3DSA:3.40.50.1980 188 308 2.2E-40 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 77 96 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 33 54 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 137 156 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 221 239 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 266 284 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 195 212 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 244 261 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 287 305 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00691 Adhesin B signature 58 76 4.4E-93 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 195 216 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 77 94 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 248 266 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 274 293 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 64 77 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PRINTS PR00690 Adhesin family signature 33 51 5.1E-55 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PANTHER PTHR30477:SF12 5 306 1.5E-123 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 Gene3D G3DSA:3.40.50.1980 19 187 1.2E-54 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 PANTHER PTHR30477 5 306 1.5E-123 T 23-04-2016 SPYM18_RS02170 1cc56ff38ec59148879dfce7a2505feb 310 Pfam PF01297 Zinc-uptake complex component A periplasmic 36 306 2.3E-72 T 23-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PANTHER PTHR24423 216 436 1.1E-65 T 23-04-2016 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PANTHER PTHR24423 1 7 1.1E-65 T 23-04-2016 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 SUPERFAMILY SSF47384 209 284 8.44E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 Pfam PF00512 His Kinase A (phospho-acceptor) domain 220 285 1.6E-8 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 Gene3D G3DSA:3.30.565.10 273 436 4.4E-36 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 436 1.4E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 SMART SM00388 218 285 2.4E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 393 2.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 379 2.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 418 2.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 436 2.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 Gene3D G3DSA:1.10.287.130 213 272 3.2E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 SMART SM00387 328 436 2.7E-28 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 SUPERFAMILY SSF55874 296 436 5.63E-35 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PANTHER PTHR24423:SF546 216 436 1.1E-65 T 23-04-2016 SPYM18_RS05130 476a7b78cb184dbe628d29afd9adb047 436 PANTHER PTHR24423:SF546 1 7 1.1E-65 T 23-04-2016 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 SMART SM01209 102 294 2.2E-132 T 23-04-2016 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 23-04-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 416 5.0E-19 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Gene3D G3DSA:3.30.470.20 190 317 3.5E-56 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 101 8.2E-30 T 23-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 41.054 T 23-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Gene3D G3DSA:3.90.600.10 328 419 2.2E-20 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 SUPERFAMILY SSF51246 326 419 7.85E-20 T 23-04-2016 IPR011054 Rudiment single hybrid motif SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Gene3D G3DSA:3.30.1490.20 120 189 8.6E-32 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Gene3D G3DSA:3.40.50.20 2 94 7.1E-32 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 SMART SM01210 327 419 5.0E-26 T 23-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 SUPERFAMILY SSF56059 103 319 4.07E-65 T 23-04-2016 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 294 1.2E-80 T 23-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 PANTHER PTHR10520 1 421 5.8E-214 T 23-04-2016 SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 SUPERFAMILY SSF52440 2 101 7.34E-29 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS00300 3ace260431f237718fe5a147463f3bee 421 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 419 1.9E-144 T 23-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 23-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 Gene3D G3DSA:3.30.420.40 3 203 8.9E-10 T 23-04-2016 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 SUPERFAMILY SSF53067 156 395 2.59E-85 T 23-04-2016 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 Pfam PF00871 Acetokinase family 4 389 2.9E-149 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 Gene3D G3DSA:3.30.420.40 204 394 4.1E-73 T 23-04-2016 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 SUPERFAMILY SSF53067 1 194 8.55E-66 T 23-04-2016 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PANTHER PTHR21060:SF11 1 394 4.6E-198 T 23-04-2016 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PIRSF PIRSF000722 1 398 2.3E-142 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 23-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 172 185 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 323 339 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 376 388 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 4 15 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 202 223 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PRINTS PR00471 Acetate kinase family signature 301 314 4.1E-38 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 Hamap MF_00020 Acetate kinase [ackA]. 1 398 180.927 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 4.5E-150 T 23-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS00685 e06c9c9140864c69151397e172e09380 398 PANTHER PTHR21060 1 394 4.6E-198 T 23-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 SPYM18_RS02235 ad133d79e9c9ae8e50f82d09dd9c81c7 393 SMART SM00257 48 92 4.6E-8 T 23-04-2016 IPR018392 LysM domain SPYM18_RS02235 ad133d79e9c9ae8e50f82d09dd9c81c7 393 Gene3D G3DSA:3.10.350.10 47 90 6.7E-9 T 23-04-2016 IPR018392 LysM domain SPYM18_RS02235 ad133d79e9c9ae8e50f82d09dd9c81c7 393 SUPERFAMILY SSF54106 47 90 3.53E-7 T 23-04-2016 IPR018392 LysM domain SPYM18_RS02235 ad133d79e9c9ae8e50f82d09dd9c81c7 393 Pfam PF01476 LysM domain 49 89 1.1E-6 T 23-04-2016 IPR018392 LysM domain SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 Gene3D G3DSA:3.50.50.60 113 326 2.1E-49 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 317 9.0E-65 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 Gene3D G3DSA:3.50.50.60 2 112 1.1E-17 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PANTHER PTHR22912 3 453 5.3E-204 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.2E-24 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 4.2E-24 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 246 262 4.2E-24 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 272 294 4.2E-24 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 4.2E-24 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 347 441 6.7E-12 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PANTHER PTHR22912:SF147 3 453 5.3E-204 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 SUPERFAMILY SSF55424 333 454 3.78E-32 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 Gene3D G3DSA:3.30.390.30 346 454 2.6E-35 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 SUPERFAMILY SSF51905 2 326 4.26E-39 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 107 116 1.1E-6 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 247 261 1.1E-6 T 23-04-2016 SPYM18_RS04800 daf7f6772a2033bf2ab9ad69824818ad 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 287 294 1.1E-6 T 23-04-2016 SPYM18_RS06610 743519504019bc143a5772c99f03f843 218 Pfam PF04472 Protein of unknown function (DUF552) 127 195 1.8E-17 T 23-04-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 SPYM18_RS06610 743519504019bc143a5772c99f03f843 218 Hamap MF_01197 Cell division protein SepF [sepF]. 4 203 19.254 T 23-04-2016 IPR023052 Cell division protein SepF GO:0090529 SPYM18_RS06610 743519504019bc143a5772c99f03f843 218 PANTHER PTHR35798:SF1 79 218 7.0E-21 T 23-04-2016 SPYM18_RS06610 743519504019bc143a5772c99f03f843 218 PANTHER PTHR35798 79 218 7.0E-21 T 23-04-2016 SPYM18_RS03560 465e7332ff9b46595b15105cf8d2f1e3 62 Pfam PF11772 DNA-directed RNA polymerase subunit beta 15 61 2.7E-19 T 23-04-2016 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA SPYM18_RS03560 465e7332ff9b46595b15105cf8d2f1e3 62 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 1 59 2.0E-11 T 23-04-2016 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 23-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 Pfam PF01207 Dihydrouridine synthase (Dus) 20 319 4.6E-88 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 PANTHER PTHR11082:SF25 1 322 9.9E-136 T 23-04-2016 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 322 9.5E-106 T 23-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 SUPERFAMILY SSF51395 17 324 2.93E-82 T 23-04-2016 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 PANTHER PTHR11082 1 322 9.9E-136 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 Gene3D G3DSA:3.20.20.70 14 252 1.8E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 Gene3D G3DSA:1.10.1200.80 260 324 6.2E-20 T 23-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 SPYM18_RS00735 7d7ce589427ff139d8487942eabff58c 325 PIRSF PIRSF006621 7 324 1.3E-104 T 23-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Gene3D G3DSA:3.30.420.40 1 138 4.4E-52 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 454 9.9E-20 T 23-04-2016 IPR021873 Cell division protein FtsA, C-terminal SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 SUPERFAMILY SSF53067 6 194 7.48E-56 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 PIRSF PIRSF003101 1 453 3.5E-126 T 23-04-2016 IPR020823 Cell division protein FtsA GO:0007049 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 PANTHER PTHR32432 1 403 1.1E-134 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 370 2.9E-97 T 23-04-2016 IPR020823 Cell division protein FtsA GO:0007049 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Gene3D G3DSA:3.90.640.10 233 295 1.4E-21 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 SUPERFAMILY SSF53067 197 365 1.87E-37 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Gene3D G3DSA:3.30.420.40 296 348 1.7E-17 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Gene3D G3DSA:3.30.420.40 195 232 1.7E-17 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Pfam PF14450 Cell division protein FtsA 206 365 9.3E-17 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Pfam PF14450 Cell division protein FtsA 9 183 1.3E-8 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 PANTHER PTHR32432:SF4 1 403 1.1E-134 T 23-04-2016 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Pfam PF02491 SHS2 domain inserted in FTSA 85 160 7.6E-21 T 23-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 453 27.761 T 23-04-2016 IPR020823 Cell division protein FtsA GO:0007049 SPYM18_RS06625 301b508eeda3308a5f35bfa51de0e593 454 SMART SM00842 7 194 3.2E-86 T 23-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 PANTHER PTHR22749:SF3 1 300 7.5E-93 T 23-04-2016 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 303 3.3E-74 T 23-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 PANTHER PTHR22749 1 300 7.5E-93 T 23-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 Gene3D G3DSA:2.40.30.30 178 306 2.4E-37 T 23-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 Gene3D G3DSA:3.40.50.620 13 177 3.4E-46 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 PIRSF PIRSF004491 1 310 5.8E-91 T 23-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 Pfam PF01687 Riboflavin kinase 182 302 7.6E-30 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 SUPERFAMILY SSF82114 171 305 6.32E-42 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 SUPERFAMILY SSF52374 18 174 2.25E-25 T 23-04-2016 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 Pfam PF06574 FAD synthetase 13 164 1.6E-44 T 23-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 SPYM18_RS05195 d79bc27063271d2a7b838a3f5cb94825 310 SMART SM00904 181 305 3.1E-51 T 23-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 SUPERFAMILY SSF50129 1 184 1.95E-54 T 23-04-2016 IPR011032 GroES-like SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 Gene3D G3DSA:3.90.180.10 1 171 5.0E-51 T 23-04-2016 IPR011032 GroES-like SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 PANTHER PTHR11695 12 347 4.9E-120 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 SMART SM00829 8 344 0.0033 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 PANTHER PTHR11695:SF559 12 347 4.9E-120 T 23-04-2016 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 1.3E-26 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 SUPERFAMILY SSF51735 139 310 2.22E-38 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 Pfam PF00107 Zinc-binding dehydrogenase 177 292 2.1E-23 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SPYM18_RS04625 69a6f6a13fc03b4f298e8cac070060fe 349 Gene3D G3DSA:3.40.50.720 172 287 5.5E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 Gene3D G3DSA:1.10.150.170 117 221 2.2E-38 T 23-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 Gene3D G3DSA:3.40.50.150 222 315 1.9E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 Gene3D G3DSA:3.40.50.150 7 114 1.9E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 SUPERFAMILY SSF81799 118 219 3.01E-34 T 23-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 SUPERFAMILY SSF53335 6 117 8.46E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 SUPERFAMILY SSF53335 219 314 8.46E-42 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 Pfam PF01795 MraW methylase family 4 314 7.3E-130 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 PIRSF PIRSF004486 1 315 2.7E-105 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 37.164 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 313 4.1E-117 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 PANTHER PTHR11265:SF0 4 316 1.1E-140 T 23-04-2016 SPYM18_RS07225 7b41c24923921ef56709ebc21d3cd42e 316 PANTHER PTHR11265 4 316 1.1E-140 T 23-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF10385 RNA polymerase beta subunit external 1 domain 551 618 4.4E-22 T 23-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 PANTHER PTHR20856 2 291 0.0 T 23-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 PANTHER PTHR20856 383 1147 0.0 T 23-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF00562 RNA polymerase Rpb2, domain 6 679 1065 3.3E-164 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF04560 RNA polymerase Rpb2, domain 7 1067 1141 1.0E-25 T 23-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 220 892 2.0E-291 T 23-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 PANTHER PTHR20856:SF20 2 291 0.0 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 PANTHER PTHR20856:SF20 383 1147 0.0 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:2.40.50.150 782 914 6.5E-58 T 23-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF04565 RNA polymerase Rpb2, domain 3 473 538 2.1E-28 T 23-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:2.30.150.10 552 618 8.3E-24 T 23-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:3.90.1110.10 380 404 4.0E-64 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:3.90.1110.10 142 300 4.0E-64 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1143 12.274 T 23-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:2.40.270.10 748 775 1.3E-80 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:2.40.270.10 915 1043 1.3E-80 T 23-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 SUPERFAMILY SSF64484 382 1151 0.0 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 SUPERFAMILY SSF64484 14 291 0.0 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 290 3.8E-23 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF04561 RNA polymerase Rpb2, domain 2 368 414 3.4E-8 T 23-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Pfam PF04563 RNA polymerase beta subunit 28 460 1.2E-28 T 23-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:2.40.50.100 677 747 3.1E-26 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:3.90.1100.10 21 140 1.3E-145 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:3.90.1100.10 405 551 1.3E-145 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 Gene3D G3DSA:3.90.1100.10 621 675 1.3E-145 T 23-04-2016 SPYM18_RS00630 9e3402db7307087f1831f0ae91b876ae 1188 ProSitePatterns PS01166 RNA polymerases beta chain signature. 918 930 - T 23-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 Pfam PF01761 3-dehydroquinate synthase 67 322 1.4E-93 T 23-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 3 355 35.004 T 23-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 351 8.4E-120 T 23-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 PIRSF PIRSF001455 4 357 7.4E-125 T 23-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 SUPERFAMILY SSF56796 4 353 1.09E-93 T 23-04-2016 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 PANTHER PTHR21090 1 334 3.2E-109 T 23-04-2016 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 Gene3D G3DSA:3.40.50.1970 4 171 7.6E-57 T 23-04-2016 SPYM18_RS06840 4f00adae6e2ab2efa83caa453e66af8f 357 Gene3D G3DSA:1.20.1090.10 172 347 3.2E-52 T 23-04-2016 SPYM18_RS08770 6a06a919e2536695f02292a75274accb 115 SUPERFAMILY SSF52833 3 112 6.35E-21 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS08770 6a06a919e2536695f02292a75274accb 115 Pfam PF00085 Thioredoxin 22 114 2.7E-6 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 SPYM18_RS08770 6a06a919e2536695f02292a75274accb 115 Gene3D G3DSA:3.40.30.10 2 113 9.2E-29 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 795 46.684 T 23-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:3.30.930.10 493 694 5.3E-61 T 23-04-2016 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:3.30.56.10 1 38 9.7E-25 T 23-04-2016 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Pfam PF03484 tRNA synthetase B5 domain 411 476 1.1E-15 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 801 5.6E-255 T 23-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:2.40.50.140 41 228 6.9E-51 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:3.30.70.380 710 801 1.9E-30 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SUPERFAMILY SSF46955 408 480 3.57E-18 T 23-04-2016 IPR009061 Putative DNA-binding domain SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SMART SM00873 218 391 5.6E-84 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SMART SM00874 408 476 6.2E-25 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SUPERFAMILY SSF54991 703 801 4.18E-30 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 PANTHER PTHR10947:SF0 2 801 9.8E-288 T 23-04-2016 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 PANTHER PTHR10947 2 801 9.8E-288 T 23-04-2016 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:3.50.40.10 229 399 6.4E-77 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SMART SM00896 708 801 8.5E-41 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Gene3D G3DSA:3.30.56.20 407 480 2.2E-23 T 23-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SUPERFAMILY SSF55681 472 694 3.93E-47 T 23-04-2016 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SUPERFAMILY SSF56037 217 400 2.62E-66 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Pfam PF03147 Ferredoxin-fold anticodon binding domain 709 801 2.2E-28 T 23-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Pfam PF01588 Putative tRNA binding domain 45 148 2.5E-19 T 23-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 SUPERFAMILY SSF50249 35 196 3.43E-43 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03575 f49d06a9f9c094c22e0c51d5df605eaf 801 Pfam PF03483 B3/4 domain 221 390 1.3E-63 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 442 2.5E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 SUPERFAMILY SSF47384 228 306 3.14E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 PANTHER PTHR24423 60 75 5.5E-36 T 23-04-2016 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 PANTHER PTHR24423 169 437 5.5E-36 T 23-04-2016 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 SUPERFAMILY SSF55874 312 457 7.33E-21 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 307 6.3E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 SMART SM00387 351 460 3.4E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 Gene3D G3DSA:1.10.287.130 234 304 2.0E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 SMART SM00388 242 308 7.4E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 Pfam PF00672 HAMP domain 159 222 1.7E-7 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 Gene3D G3DSA:3.30.565.10 313 460 6.5E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS08960 37a0429de4bd7f93614cfaff74fdca9b 462 SMART SM00304 175 227 2.0E-4 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 3 200 3.9E-34 T 23-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 SUPERFAMILY SSF102645 3 228 9.16E-52 T 23-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 PANTHER PTHR14359:SF22 3 98 1.7E-60 T 23-04-2016 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 PANTHER PTHR14359:SF22 119 226 1.7E-60 T 23-04-2016 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 PANTHER PTHR14359 3 98 1.7E-60 T 23-04-2016 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 PANTHER PTHR14359 119 226 1.7E-60 T 23-04-2016 SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 TIGRFAM TIGR02114 coaB_strep: phosphopantothenate--cysteine ligase 3 230 8.4E-123 T 23-04-2016 IPR011848 Phosphopantothenate--cysteine ligase SPYM18_RS05070 f3f392130000b4ab5776ee3875236e26 230 Gene3D G3DSA:3.40.50.10300 3 228 1.1E-51 T 23-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 Gene3D G3DSA:1.20.58.90 241 298 1.2E-6 T 23-04-2016 SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 SUPERFAMILY SSF55729 306 402 4.94E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 SUPERFAMILY SSF55729 166 239 4.94E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 Gene3D G3DSA:3.40.630.30 1 161 1.3E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 Gene3D G3DSA:3.40.630.30 162 238 6.4E-44 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 Gene3D G3DSA:3.40.630.30 305 380 6.4E-44 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 SUPERFAMILY SSF55729 1 159 2.79E-40 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 Pfam PF02388 FemAB family 6 406 2.7E-139 T 23-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 PANTHER PTHR36174:SF2 1 410 1.1E-117 T 23-04-2016 SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 PANTHER PTHR36174 1 410 1.1E-117 T 23-04-2016 SPYM18_RS02910 c3a650f075ca8fdb0e15bd00cdc07559 411 SUPERFAMILY SSF46589 239 302 2.46E-18 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PANTHER PTHR11707 4 320 1.7E-54 T 23-04-2016 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 Pfam PF00710 Asparaginase, N-terminal 3 187 8.7E-58 T 23-04-2016 IPR027474 L-asparaginase, N-terminal SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 23-04-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 SUPERFAMILY SSF53774 1 320 6.8E-95 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PIRSF PIRSF500176 1 321 1.4E-98 T 23-04-2016 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 SMART SM00870 3 316 2.0E-133 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PIRSF PIRSF001220 1 320 1.2E-94 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 4.6E-17 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PRINTS PR00139 Asparaginase/glutaminase family signature 251 269 4.6E-17 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 PRINTS PR00139 Asparaginase/glutaminase family signature 76 94 4.6E-17 T 23-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 77 87 - T 23-04-2016 IPR027475 Asparaginase/glutaminase, active site 2 SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 Gene3D G3DSA:3.40.50.40 204 320 1.9E-28 T 23-04-2016 IPR027473 L-asparaginase, C-terminal domain SPYM18_RS08000 9d10c99537eae1028d874c297a5c60c0 321 Gene3D G3DSA:3.40.50.1170 1 192 1.2E-61 T 23-04-2016 IPR027474 L-asparaginase, N-terminal SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF00128 Alpha amylase, catalytic domain 573 673 2.6E-12 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF00128 Alpha amylase, catalytic domain 710 902 4.1E-6 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1132 1165 2.9E-7 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 TIGRFAM TIGR02102 pullulan_Gpos: pullulanase, extracellular 91 1165 0.0 T 23-04-2016 IPR011838 Pullulanase, extracellular SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SMART SM00642 547 928 4.1E-7 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SUPERFAMILY SSF49452 200 308 9.81E-30 T 23-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 408 496 1.8E-11 T 23-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357 938 1088 1.8E-128 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357 391 781 1.8E-128 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357 803 911 1.8E-128 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Gene3D G3DSA:3.20.20.80 547 984 4.4E-98 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Gene3D G3DSA:2.60.40.10 408 546 1.6E-19 T 23-04-2016 IPR013783 Immunoglobulin-like fold SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SUPERFAMILY SSF51445 538 902 2.46E-99 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SUPERFAMILY SSF51445 933 983 2.46E-99 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF00746 Gram positive anchor 1127 1162 1.0E-7 T 23-04-2016 IPR019948 Gram-positive anchor SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SUPERFAMILY SSF49452 93 197 1.34E-29 T 23-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF03714 Bacterial pullanase-associated domain 204 304 8.6E-13 T 23-04-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 Pfam PF03714 Bacterial pullanase-associated domain 96 194 3.4E-12 T 23-04-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 SUPERFAMILY SSF81296 404 505 3.08E-17 T 23-04-2016 IPR014756 Immunoglobulin E-set SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357:SF99 938 1088 1.8E-128 T 23-04-2016 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357:SF99 391 781 1.8E-128 T 23-04-2016 SPYM18_RS08775 094c95a9013ca7e5546ee0f34d292bd7 1165 PANTHER PTHR10357:SF99 803 911 1.8E-128 T 23-04-2016 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 374 3.5E-163 T 23-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 PANTHER PTHR21148 1 371 2.3E-177 T 23-04-2016 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 375 5.3E-172 T 23-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 7.1E-89 T 23-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 SUPERFAMILY SSF51713 7 371 3.53E-155 T 23-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 365 56.296 T 23-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 PANTHER PTHR21148:SF26 1 371 2.3E-177 T 23-04-2016 SPYM18_RS01015 b00f6be576a4ab0dfb7acc9e6c4bc931 380 Gene3D G3DSA:3.20.20.105 6 373 6.5E-163 T 23-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS05665 6996e3f211d97da6a88202c731d2a13a 227 Pfam PF13643 Domain of unknown function (DUF4145) 125 202 4.3E-8 T 23-04-2016 IPR025285 Domain of unknown function DUF4145 SPYM18_RS02805 6a39256683184d4553d20a2ab49e1276 135 PANTHER PTHR40070:SF1 1 109 2.5E-24 T 23-04-2016 SPYM18_RS02805 6a39256683184d4553d20a2ab49e1276 135 PANTHER PTHR40070 1 109 2.5E-24 T 23-04-2016 SPYM18_RS02805 6a39256683184d4553d20a2ab49e1276 135 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 94 4.8E-30 T 23-04-2016 IPR009293 Uncharacterised protein family UPF0478 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Gene3D G3DSA:1.10.1160.10 251 335 4.9E-33 T 23-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.0E-28 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 220 5.0E-28 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.0E-28 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 206 5.0E-28 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.0E-28 T 23-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 326 1.9E-112 T 23-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 SUPERFAMILY SSF52374 5 319 2.36E-103 T 23-04-2016 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 SUPERFAMILY SSF48163 320 480 1.23E-40 T 23-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 479 5.2E-167 T 23-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Gene3D G3DSA:3.90.800.10 70 197 3.2E-33 T 23-04-2016 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Gene3D G3DSA:1.10.10.350 391 480 3.2E-18 T 23-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PANTHER PTHR11451:SF41 4 247 3.1E-98 T 23-04-2016 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PANTHER PTHR11451:SF41 263 339 3.1E-98 T 23-04-2016 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Gene3D G3DSA:3.40.50.620 198 247 2.0E-51 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Gene3D G3DSA:3.40.50.620 5 69 2.0E-51 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS01115 9404067a089b182693185cc21be53005 481 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 481 33.518 T 23-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PANTHER PTHR11451 4 247 3.1E-98 T 23-04-2016 SPYM18_RS01115 9404067a089b182693185cc21be53005 481 PANTHER PTHR11451 263 339 3.1E-98 T 23-04-2016 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 PANTHER PTHR10871 1 121 4.9E-70 T 23-04-2016 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 Gene3D G3DSA:1.10.8.50 1 71 5.8E-30 T 23-04-2016 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 113 6.4E-52 T 23-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 Gene3D G3DSA:4.10.910.10 72 121 5.2E-28 T 23-04-2016 IPR027437 30s ribosomal protein S13, C-terminal SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 Pfam PF00416 Ribosomal protein S13/S18 62 108 1.7E-18 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 PIRSF PIRSF002134 1 121 2.2E-43 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.382 T 23-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 23-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00485 bd3518152eff44a233cf753342902979 121 SUPERFAMILY SSF46946 2 112 5.74E-45 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SPYM18_RS03690 759d59550782542f90a1e6dca45c9eba 113 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 6 109 2.1E-30 T 23-04-2016 IPR019277 Protein of unknown function DUF2304 SPYM18_RS08295 37c76260a9d549c0537fb3992ddf38d3 124 SUPERFAMILY SSF47413 6 71 1.21E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08295 37c76260a9d549c0537fb3992ddf38d3 124 SMART SM00530 11 67 2.4E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08295 37c76260a9d549c0537fb3992ddf38d3 124 Pfam PF01381 Helix-turn-helix 12 66 1.3E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08295 37c76260a9d549c0537fb3992ddf38d3 124 Gene3D G3DSA:1.10.260.40 4 71 4.7E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 8.3E-26 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Pfam PF01926 50S ribosome-binding GTPase 177 295 1.4E-25 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Gene3D G3DSA:3.30.300.20 358 436 1.3E-37 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 PANTHER PTHR11649 1 436 1.3E-145 T 23-04-2016 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Hamap MF_00195 GTPase Der [der]. 3 436 39.871 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Gene3D G3DSA:3.40.50.300 3 169 3.2E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Gene3D G3DSA:3.40.50.300 170 357 2.8E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 SUPERFAMILY SSF52540 138 435 1.58E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 343 4.8E-26 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 125 3.4E-23 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 3.3E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 3.3E-6 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 PANTHER PTHR11649:SF5 1 436 1.3E-145 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 PIRSF PIRSF006485 2 436 2.6E-169 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 1.1E-32 T 23-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 SUPERFAMILY SSF52540 4 165 1.01E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01530 e65c03ffa3ff246b57af8b25c077d865 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 2.1E-172 T 23-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 4.1E-51 T 23-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 PANTHER PTHR10210:SF41 1 317 1.3E-183 T 23-04-2016 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 SUPERFAMILY SSF53271 71 308 1.51E-61 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 5.6E-22 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 317 1.9E-121 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 SMART SM01400 6 122 1.2E-79 T 23-04-2016 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 317 50.056 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 23-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 PANTHER PTHR10210 1 317 1.3E-183 T 23-04-2016 SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 Gene3D G3DSA:3.40.50.2020 162 289 4.8E-50 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS00245 4ed21e9df625d5897ae6487d501e1bc2 320 Gene3D G3DSA:3.40.50.2020 3 161 1.8E-75 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS07515 9520cac2f16f732f1819930d6340ac8d 197 Gene3D G3DSA:3.40.630.30 134 183 1.4E-6 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS07515 9520cac2f16f732f1819930d6340ac8d 197 SUPERFAMILY SSF55729 134 194 9.56E-7 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 TIGRFAM TIGR03107 glu_aminopep: glutamyl aminopeptidase 5 353 2.1E-196 T 23-04-2016 IPR017538 Peptidase M42, glutamyl aminopeptidase MetaCyc: PWY-5706|MetaCyc: PWY-5707|MetaCyc: PWY-7614 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 SUPERFAMILY SSF101821 71 182 1.19E-25 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 Pfam PF05343 M42 glutamyl aminopeptidase 45 334 2.5E-95 T 23-04-2016 IPR008007 Peptidase M42 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 Gene3D G3DSA:3.40.630.10 171 354 6.3E-73 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 Gene3D G3DSA:3.40.630.10 2 74 6.3E-73 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 PANTHER PTHR32481:SF0 1 355 9.0E-147 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 PANTHER PTHR32481 1 355 9.0E-147 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 PIRSF PIRSF001123 1 355 5.7E-131 T 23-04-2016 IPR008007 Peptidase M42 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 SUPERFAMILY SSF53187 4 81 1.59E-57 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 SUPERFAMILY SSF53187 174 353 1.59E-57 T 23-04-2016 SPYM18_RS00700 6021084221cec6fd8cd5d7cdddf0f4ad 355 Gene3D G3DSA:2.40.30.40 76 164 1.6E-27 T 23-04-2016 IPR023367 Peptidase M42, domain 2 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 23-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Pfam PF00204 DNA gyrase B 229 399 5.8E-57 T 23-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 249 267 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 600 612 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 11 21 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 481 490 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 319 335 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 383 403 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 187 202 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 616 632 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 202 215 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR01159 DNA gyrase subunit B signature 369 383 6.9E-51 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 SUPERFAMILY SSF55874 10 217 2.49E-66 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 SUPERFAMILY SSF54211 229 399 1.82E-53 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PANTHER PTHR10169:SF44 9 639 0.0 T 23-04-2016 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Pfam PF01751 Toprim domain 430 540 1.9E-17 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 9 645 50.146 T 23-04-2016 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Gene3D G3DSA:3.30.230.10 228 399 8.4E-64 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 SMART SM00387 36 182 2.7E-24 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 9 648 0.0 T 23-04-2016 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 180 1.3E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 SMART SM00433 40 640 0.0 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 577 636 3.4E-28 T 23-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Gene3D G3DSA:3.40.50.670 416 627 6.1E-86 T 23-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 SUPERFAMILY SSF56719 405 646 6.54E-87 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 515 532 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 579 595 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 75 88 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 535 547 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 117 131 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 431 445 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 40 55 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 275 288 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PRINTS PR00418 DNA topoisomerase II family signature 497 513 4.5E-70 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 Gene3D G3DSA:3.30.565.10 11 218 8.0E-85 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04170 124ce2a0209aae66e64d853075853247 649 PANTHER PTHR10169 9 639 0.0 T 23-04-2016 SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 PANTHER PTHR33370 2 72 7.6E-46 T 23-04-2016 SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 5.0E-28 T 23-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 SUPERFAMILY SSF50249 2 71 4.63E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 Gene3D G3DSA:2.40.50.140 2 72 1.1E-39 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 SMART SM00316 4 72 2.2E-6 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.723 T 23-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SPYM18_RS00480 afbaf50b4547b2a94fdd5680c3a075d5 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.4E-38 T 23-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 PANTHER PTHR30061:SF1 6 259 9.3E-24 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 Pfam PF12010 Domain of unknown function (DUF3502) 348 478 9.3E-38 T 23-04-2016 IPR022627 Domain of unknown function DUF3502 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 SUPERFAMILY SSF53850 22 476 3.02E-88 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 Pfam PF13416 Bacterial extracellular solute-binding protein 58 338 3.6E-17 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 Gene3D G3DSA:3.40.190.10 152 347 3.2E-29 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 Gene3D G3DSA:3.40.190.10 424 476 3.2E-29 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 PANTHER PTHR30061 6 259 9.3E-24 T 23-04-2016 SPYM18_RS06885 7f3bbd7897c8327354d336ceab4b207b 481 Gene3D G3DSA:3.40.190.10 57 149 8.1E-19 T 23-04-2016 SPYM18_RS03655 47dc9ba5a1dac1b8760c188ffd9cc340 310 Pfam PF00535 Glycosyl transferase family 2 5 113 5.0E-19 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS03655 47dc9ba5a1dac1b8760c188ffd9cc340 310 Gene3D G3DSA:3.90.550.10 3 225 3.0E-37 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03655 47dc9ba5a1dac1b8760c188ffd9cc340 310 SUPERFAMILY SSF53448 3 239 2.81E-43 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03655 47dc9ba5a1dac1b8760c188ffd9cc340 310 PANTHER PTHR22916:SF23 1 213 3.8E-24 T 23-04-2016 SPYM18_RS03655 47dc9ba5a1dac1b8760c188ffd9cc340 310 PANTHER PTHR22916 1 213 3.8E-24 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PANTHER PTHR10617:SF103 325 388 3.4E-123 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PANTHER PTHR10617:SF103 1 288 3.4E-123 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 387 1.8E-132 T 23-04-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 2.6E-8 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 357 364 2.6E-8 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.6E-8 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 342 364 1.9E-7 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-7 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.9E-7 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PANTHER PTHR10617 325 388 3.4E-123 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 PANTHER PTHR10617 1 288 3.4E-123 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 Gene3D G3DSA:2.40.30.10 192 270 8.1E-23 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 Gene3D G3DSA:1.10.8.260 271 316 3.9E-4 T 23-04-2016 IPR023166 HI0933 insert-like domain SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 Pfam PF03486 HI0933-like protein 4 387 6.7E-142 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 SUPERFAMILY SSF160996 193 335 4.84E-32 T 23-04-2016 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 SUPERFAMILY SSF51905 1 191 6.5E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 SUPERFAMILY SSF51905 332 387 6.5E-53 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 Gene3D G3DSA:3.50.50.60 334 387 9.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS08320 94cc57386038ff6cb8f961836d4012a1 389 Gene3D G3DSA:3.50.50.60 1 189 9.7E-50 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS05925 0bd39a06f1509d2b96d61c976bba3ce4 245 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 221 241 1.6E-10 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS05925 0bd39a06f1509d2b96d61c976bba3ce4 245 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 205 220 1.6E-10 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS05925 0bd39a06f1509d2b96d61c976bba3ce4 245 Pfam PF00746 Gram positive anchor 206 239 1.1E-8 T 23-04-2016 IPR019948 Gram-positive anchor SPYM18_RS05925 0bd39a06f1509d2b96d61c976bba3ce4 245 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 210 243 3.3E-4 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 Gene3D G3DSA:1.10.1660.10 14 102 1.4E-20 T 23-04-2016 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 PANTHER PTHR30204:SF8 5 105 9.0E-34 T 23-04-2016 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 Pfam PF13411 MerR HTH family regulatory protein 14 76 2.7E-18 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 ProSitePatterns PS00552 MerR-type HTH domain signature. 16 38 - T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 PANTHER PTHR30204 5 105 9.0E-34 T 23-04-2016 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 SMART SM00422 13 82 1.4E-19 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08380 72c76f1261c99f42b507dae3d7b0c132 123 SUPERFAMILY SSF46955 13 82 3.39E-18 T 23-04-2016 IPR009061 Putative DNA-binding domain SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 SUPERFAMILY SSF55205 3 424 5.36E-132 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 23-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 421 9.4E-119 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 Gene3D G3DSA:3.65.10.10 229 424 4.1E-52 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 426 3.2E-128 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 23-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 PIRSF PIRSF000505 1 427 1.8E-114 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 Gene3D G3DSA:3.65.10.10 20 228 2.7E-61 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 427 33.449 T 23-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 PANTHER PTHR21090:SF5 5 424 2.5E-169 T 23-04-2016 SPYM18_RS05900 43ff3023091015af3c7f9ccf8644a118 427 PANTHER PTHR21090 5 424 2.5E-169 T 23-04-2016 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 PANTHER PTHR32120 2 290 6.4E-114 T 23-04-2016 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Pfam PF16745 RsgA N-terminal domain 2 55 1.9E-24 T 23-04-2016 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 SUPERFAMILY SSF50249 2 62 3.26E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Gene3D G3DSA:2.40.50.140 2 60 3.4E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Pfam PF03193 Protein of unknown function, DUF258 58 215 3.0E-57 T 23-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 SUPERFAMILY SSF52540 64 280 2.35E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 1 280 38.237 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Gene3D G3DSA:1.10.40.50 219 288 5.5E-26 T 23-04-2016 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 Gene3D G3DSA:3.40.50.300 62 214 2.7E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 273 8.3E-75 T 23-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 SPYM18_RS01215 b326aad004f8d3a118d5ae362407aabf 290 PANTHER PTHR32120:SF2 2 290 6.4E-114 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 PANTHER PTHR21262 10 739 0.0 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 736 2.3E-236 T 23-04-2016 IPR004811 RelA/SpoT family GO:0015969 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Gene3D G3DSA:3.30.460.10 183 328 8.9E-47 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Pfam PF04607 Region found in RelA / SpoT proteins 240 348 2.3E-36 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SUPERFAMILY SSF55021 661 736 1.54E-9 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Pfam PF13291 ACT domain 658 736 1.7E-20 T 23-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SMART SM00954 240 349 1.7E-60 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 PANTHER PTHR21262:SF0 10 739 0.0 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SUPERFAMILY SSF81301 199 370 1.11E-61 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Pfam PF02824 TGS domain 395 454 1.7E-21 T 23-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SUPERFAMILY SSF109604 10 196 2.92E-75 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Gene3D G3DSA:3.30.70.260 661 735 1.6E-11 T 23-04-2016 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SUPERFAMILY SSF81271 382 455 2.14E-20 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Gene3D G3DSA:3.10.20.30 394 455 2.6E-22 T 23-04-2016 IPR012675 Beta-grasp domain SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 Pfam PF13328 HD domain 31 180 1.1E-48 T 23-04-2016 IPR003607 HD/PDEase domain SPYM18_RS08805 6a2ca8db49825bc8e223b52b6120612d 739 SMART SM00471 46 158 8.4E-9 T 23-04-2016 IPR003607 HD/PDEase domain SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 Hamap MF_01557 Tagatose-6-phosphate kinase [lacC]. 1 309 58.492 T 23-04-2016 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 Pfam PF00294 pfkB family carbohydrate kinase 11 291 2.6E-57 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 307 1.2E-91 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 PIRSF PIRSF000535 1 309 4.1E-134 T 23-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 Gene3D G3DSA:2.20.150.10 9 34 8.9E-6 T 23-04-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 PANTHER PTHR10584 1 304 2.0E-145 T 23-04-2016 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 SUPERFAMILY SSF53613 2 289 1.11E-61 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 Gene3D G3DSA:3.40.1190.20 35 308 7.1E-80 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 TIGRFAM TIGR01231 lacC: tagatose-6-phosphate kinase 2 309 7.8E-144 T 23-04-2016 IPR005926 Tagatose-6-phosphate kinase GO:0009024|GO:0019512 KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 SPYM18_RS08585 a7d6ad706a124e6afdd769e677fbc35e 309 PANTHER PTHR10584:SF178 1 304 2.0E-145 T 23-04-2016 SPYM18_RS02645 4102bd866439fbc62ddf0fa5bde1ba89 69 SUPERFAMILY SSF47413 5 67 1.95E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02645 4102bd866439fbc62ddf0fa5bde1ba89 69 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 7 66 6.1E-19 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS02645 4102bd866439fbc62ddf0fa5bde1ba89 69 Gene3D G3DSA:1.10.260.40 6 67 2.6E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS07365 0b090cd1c4a75e6a0d8557fc83de245f 87 PANTHER PTHR10584:SF178 1 54 3.2E-16 T 23-04-2016 SPYM18_RS07365 0b090cd1c4a75e6a0d8557fc83de245f 87 SUPERFAMILY SSF53613 3 78 6.54E-7 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS07365 0b090cd1c4a75e6a0d8557fc83de245f 87 Gene3D G3DSA:3.40.1190.20 2 79 8.9E-9 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS07365 0b090cd1c4a75e6a0d8557fc83de245f 87 PANTHER PTHR10584 1 54 3.2E-16 T 23-04-2016 SPYM18_RS09020 d46d72881a6fbc829451eb26080d9e2e 271 SMART SM00892 89 270 5.2E-7 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS09020 d46d72881a6fbc829451eb26080d9e2e 271 Pfam PF01223 DNA/RNA non-specific endonuclease 71 267 1.4E-16 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 Gene3D G3DSA:1.20.1250.20 237 441 5.1E-26 T 23-04-2016 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 PIRSF PIRSF002808 4 445 4.7E-75 T 23-04-2016 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 Gene3D G3DSA:1.20.1250.20 19 216 1.6E-36 T 23-04-2016 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 SUPERFAMILY SSF103473 9 438 8.76E-61 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 PANTHER PTHR11662 23 441 5.4E-66 T 23-04-2016 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 PANTHER PTHR11662:SF141 23 441 5.4E-66 T 23-04-2016 SPYM18_RS02135 6451a1c5f543bbbb3aca2a9333a29a6f 445 Pfam PF07690 Major Facilitator Superfamily 27 397 2.3E-42 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Gene3D G3DSA:3.90.740.10 205 382 3.7E-46 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 634 3.0E-203 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Gene3D G3DSA:3.40.50.620 394 632 2.6E-143 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Gene3D G3DSA:3.40.50.620 16 203 2.6E-143 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 3.4E-27 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.4E-27 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 3.4E-27 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 3.4E-27 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 3.4E-27 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Gene3D G3DSA:1.10.730.10 634 818 8.5E-42 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 834 8.6E-284 T 23-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 917 19.228 T 23-04-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 SUPERFAMILY SSF50677 202 393 5.97E-44 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 SUPERFAMILY SSF52374 1 200 8.45E-150 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 SUPERFAMILY SSF52374 394 640 8.45E-150 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946 5 249 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946 886 918 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946 274 866 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 SUPERFAMILY SSF47323 645 917 9.72E-70 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946:SF11 5 249 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946:SF11 886 918 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 PANTHER PTHR11946:SF11 274 866 0.0 T 23-04-2016 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 Pfam PF08264 Anticodon-binding domain of tRNA 678 832 5.1E-26 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 SPYM18_RS06590 858bee13a78ca7e753e4c2585dddf220 933 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS07635 e15bca8834d1eb5c3c01148d8fe76b1e 497 Pfam PF06152 Phage minor capsid protein 2 8 362 4.9E-102 T 23-04-2016 IPR009319 Bacteriophage A118, Gp4, minor capsid GO:0005198|GO:0019028 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 PANTHER PTHR21535 20 297 3.8E-26 T 23-04-2016 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 Pfam PF01544 CorA-like Mg2+ transporter protein 11 299 1.9E-41 T 23-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 PANTHER PTHR21535:SF40 20 297 3.8E-26 T 23-04-2016 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 SUPERFAMILY SSF144083 237 297 1.57E-9 T 23-04-2016 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 SUPERFAMILY SSF143865 14 236 4.71E-21 T 23-04-2016 SPYM18_RS06790 20472cf209874de3f4c19a19ce2d287c 310 Gene3D G3DSA:1.20.58.340 227 301 7.8E-13 T 23-04-2016 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 1.0E-36 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 42.576 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PIRSF PIRSF001529 1 425 1.8E-185 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 7.0E-178 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 SUPERFAMILY SSF55681 117 422 1.97E-110 T 23-04-2016 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 Gene3D G3DSA:3.30.930.10 106 419 3.1E-146 T 23-04-2016 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 1.0E-29 T 23-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 SUPERFAMILY SSF46589 1 113 1.94E-28 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PANTHER PTHR11778 1 425 4.4E-218 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 1.2E-34 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 1.2E-34 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 1.2E-34 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 1.2E-34 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 1.2E-34 T 23-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 SPYM18_RS07840 149840b1743539b4641181c220631d68 425 Gene3D G3DSA:1.10.287.40 1 105 4.4E-22 T 23-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PANTHER PTHR24322:SF392 7 134 2.7E-67 T 23-04-2016 SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PANTHER PTHR24322:SF392 150 182 2.7E-67 T 23-04-2016 SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 SUPERFAMILY SSF51735 2 231 3.4E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PANTHER PTHR24322 7 134 2.7E-67 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PANTHER PTHR24322 150 182 2.7E-67 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 2.8E-8 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.4E-20 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 Gene3D G3DSA:3.40.50.720 2 234 1.5E-57 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS04705 90a7b2e683999414ee0409828e1c801f 251 Pfam PF00106 short chain dehydrogenase 3 190 6.2E-50 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 PANTHER PTHR30041:SF5 1 130 8.0E-64 T 23-04-2016 SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 PANTHER PTHR30041 1 130 8.0E-64 T 23-04-2016 SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 SUPERFAMILY SSF52833 1 125 1.58E-33 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 Pfam PF03960 ArsC family 7 113 2.7E-19 T 23-04-2016 IPR006660 Arsenate reductase-like SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 Gene3D G3DSA:3.40.30.10 1 114 4.4E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09295 35898028603d54798dc73a3677b3c723 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 8.1E-34 T 23-04-2016 IPR006504 Transcriptional regulator Spx/MgsR SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 PANTHER PTHR22572 6 295 4.3E-109 T 23-04-2016 SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 Pfam PF00483 Nucleotidyl transferase 6 267 2.1E-32 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 SUPERFAMILY SSF53448 1 272 2.7E-65 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 Gene3D G3DSA:3.90.550.10 5 278 1.6E-69 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 PANTHER PTHR22572:SF14 6 295 4.3E-109 T 23-04-2016 SPYM18_RS09570 31574e2059b49abca7a0422ede75934a 304 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 268 6.0E-110 T 23-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 SPYM18_RS03945 91555ddf5950acfca72c4bc46da125fd 199 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 58 190 9.6E-19 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS03945 91555ddf5950acfca72c4bc46da125fd 199 PANTHER PTHR33308 41 195 7.6E-15 T 23-04-2016 SPYM18_RS03945 91555ddf5950acfca72c4bc46da125fd 199 PANTHER PTHR33308:SF3 41 195 7.6E-15 T 23-04-2016 SPYM18_RS03945 91555ddf5950acfca72c4bc46da125fd 199 SMART SM00047 38 195 1.7E-32 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 7.1E-37 T 23-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 PANTHER PTHR21349 4 102 2.4E-39 T 23-04-2016 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 3.4E-35 T 23-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 SUPERFAMILY SSF141091 4 103 3.14E-36 T 23-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 23-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03800 c1b54004462b41bedb3e0e5099fe6fa2 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 25.343 T 23-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 SUPERFAMILY SSF51556 75 375 2.62E-80 T 23-04-2016 IPR032466 Metal-dependent hydrolase SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 PANTHER PTHR22642:SF1 6 420 9.1E-139 T 23-04-2016 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 PANTHER PTHR22642 6 420 9.1E-139 T 23-04-2016 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 SUPERFAMILY SSF51338 374 419 5.15E-18 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 SUPERFAMILY SSF51338 3 76 5.15E-18 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 Gene3D G3DSA:2.30.40.10 361 403 2.8E-6 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 Hamap MF_00372 Imidazolonepropionase [hutI]. 4 414 42.554 T 23-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 TIGRFAM TIGR01224 hutI: imidazolonepropionase 35 412 3.6E-135 T 23-04-2016 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 Gene3D G3DSA:3.20.20.140 87 360 1.2E-42 T 23-04-2016 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 Gene3D G3DSA:2.30.40.10 34 86 1.6E-9 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS09160 f978ed1dfe16782aa9f103edaac02783 421 Pfam PF01979 Amidohydrolase family 72 413 1.6E-20 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 Gene3D G3DSA:3.60.15.10 3 307 2.9E-79 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 PANTHER PTHR12553 1 156 3.7E-77 T 23-04-2016 SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 PANTHER PTHR12553 187 279 3.7E-77 T 23-04-2016 SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 Pfam PF12706 Beta-lactamase superfamily domain 206 274 1.4E-6 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 SUPERFAMILY SSF56281 1 307 1.76E-75 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 307 6.3E-108 T 23-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 Pfam PF00753 Metallo-beta-lactamase superfamily 33 82 1.3E-9 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04245 68a8a98fbaf0bda5baa595210d283d30 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 309 38.622 T 23-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 SMART SM01130 6 298 6.6E-61 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PANTHER PTHR12128:SF30 8 287 1.5E-108 T 23-04-2016 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 SUPERFAMILY SSF51569 6 291 3.66E-67 T 23-04-2016 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 Pfam PF00701 Dihydrodipicolinate synthetase family 7 288 2.5E-53 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PIRSF PIRSF001365 2 304 2.8E-74 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 76 94 4.7E-12 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 40 61 4.7E-12 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 108 124 4.7E-12 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PRINTS PR00146 Dihydrodipicolinate synthase signature 134 151 4.7E-12 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 PANTHER PTHR12128 8 287 1.5E-108 T 23-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 SPYM18_RS01185 b661610e6714145e6429a483d6b18caf 304 Gene3D G3DSA:3.20.20.70 3 290 2.3E-71 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PANTHER PTHR11652 1 129 2.7E-69 T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 Gene3D G3DSA:2.40.50.140 1 136 2.8E-61 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.602 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 SUPERFAMILY SSF50249 2 136 6.0E-47 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 Pfam PF00164 Ribosomal protein S12/S23 2 136 1.1E-39 T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 4.9E-66 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 23-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01255 f676ded77b7fe36beca4d51f3a7e7d24 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.119408E-57 T 23-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 SPYM18_RS03950 44a90b159fdbb805eae2246a8e474e6c 235 PANTHER PTHR33308:SF3 22 231 2.1E-17 T 23-04-2016 SPYM18_RS03950 44a90b159fdbb805eae2246a8e474e6c 235 PANTHER PTHR33308 22 231 2.1E-17 T 23-04-2016 SPYM18_RS03950 44a90b159fdbb805eae2246a8e474e6c 235 SMART SM00047 38 192 3.0E-38 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS03950 44a90b159fdbb805eae2246a8e474e6c 235 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 54 187 8.3E-19 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 SUPERFAMILY SSF48179 152 255 2.72E-29 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 23.926 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 PIRSF PIRSF000193 1 256 2.4E-65 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 Gene3D G3DSA:1.10.3730.10 152 255 4.4E-34 T 23-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 SUPERFAMILY SSF51735 1 149 4.69E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 256 3.4E-34 T 23-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 256 1.6E-74 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 PANTHER PTHR11645 1 256 4.5E-80 T 23-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 PANTHER PTHR11645:SF0 1 256 4.5E-80 T 23-04-2016 SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 Gene3D G3DSA:3.40.50.720 2 147 1.2E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00695 92a04cbb7a61d89bb18c085a3a31eed9 256 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 89 1.5E-13 T 23-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 Pfam PF00005 ABC transporter 20 167 5.3E-37 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 PANTHER PTHR24220 5 230 5.2E-127 T 23-04-2016 SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 SUPERFAMILY SSF52540 3 224 3.08E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 SMART SM00382 29 216 4.1E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 Gene3D G3DSA:3.40.50.300 2 222 1.3E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 PANTHER PTHR24220:SF470 5 230 5.2E-127 T 23-04-2016 SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03015 e7e0901dc528213c34023d90a5b6bd9e 230 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 3 216 1.2E-89 T 23-04-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 SUPERFAMILY SSF46561 10 67 5.76E-20 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 Pfam PF00831 Ribosomal L29 protein 11 66 3.5E-23 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 67 16.717 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 23-04-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 PANTHER PTHR10916:SF0 1 66 1.1E-21 T 23-04-2016 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 12 66 2.0E-24 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 PANTHER PTHR10916 1 66 1.1E-21 T 23-04-2016 SPYM18_RS00410 2b80610377bb564eae6e3631b2af719a 68 Gene3D G3DSA:1.10.287.310 10 67 8.3E-25 T 23-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 SUPERFAMILY SSF52540 6 160 3.89E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 6 286 28.155 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 PANTHER PTHR11088 1 269 1.6E-97 T 23-04-2016 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 274 8.4E-78 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 Pfam PF01715 IPP transferase 39 270 1.1E-72 T 23-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 Gene3D G3DSA:1.10.287.890 189 268 1.1E-30 T 23-04-2016 SPYM18_RS04230 af2e5552ec7819b196e2607666ab1ae8 299 Gene3D G3DSA:3.40.50.300 2 165 6.8E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 Pfam PF06421 GTP-binding protein LepA C-terminus 61 167 1.9E-51 T 23-04-2016 IPR013842 GTP-binding protein LepA, C-terminal SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 PANTHER PTHR23115 1 169 6.4E-80 T 23-04-2016 SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 Pfam PF00679 Elongation factor G C-terminus 5 59 7.0E-12 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 SUPERFAMILY SSF54980 6 67 3.79E-13 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 Gene3D G3DSA:3.30.70.240 6 63 5.0E-12 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS04445 e3378ebdd3ffe51a90a94dafd341a000 174 PANTHER PTHR23115:SF97 1 169 6.4E-80 T 23-04-2016 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 PANTHER PTHR30185 1 279 3.3E-112 T 23-04-2016 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Gene3D G3DSA:1.10.1790.10 66 163 1.5E-27 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Gene3D G3DSA:2.30.24.10 1 54 2.7E-18 T 23-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 SUPERFAMILY SSF63520 171 273 1.7E-25 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Gene3D G3DSA:1.10.1790.10 171 275 1.4E-29 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 SMART SM01061 1 59 1.9E-24 T 23-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 SUPERFAMILY SSF50151 1 54 1.83E-14 T 23-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Pfam PF00874 PRD domain 177 272 3.1E-19 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Pfam PF00874 PRD domain 76 163 4.3E-24 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 ProSitePatterns PS00654 PRD domain signature. 98 110 - T 23-04-2016 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 Pfam PF03123 CAT RNA binding domain 1 56 1.8E-18 T 23-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 PANTHER PTHR30185:SF2 1 279 3.3E-112 T 23-04-2016 SPYM18_RS02750 6df94647a1836a68f135c52f8df02510 280 SUPERFAMILY SSF63520 55 165 3.01E-30 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 Gene3D G3DSA:3.30.300.20 188 288 4.3E-42 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 164 1.7E-31 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 PANTHER PTHR11649 3 298 1.1E-122 T 23-04-2016 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 Gene3D G3DSA:3.40.50.300 6 187 2.8E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 Hamap MF_00367 GTPase Era [era]. 2 293 37.858 T 23-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 Pfam PF07650 KH domain 204 282 2.6E-23 T 23-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 SUPERFAMILY SSF52540 7 201 1.72E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 PANTHER PTHR11649:SF3 3 298 1.1E-122 T 23-04-2016 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 SUPERFAMILY SSF54814 177 294 8.18E-43 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 TIGRFAM TIGR00436 era: GTP-binding protein Era 5 276 2.1E-105 T 23-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 SPYM18_RS02265 18b1b9f3c4bfcf029cd0d9b8bcff2432 298 Pfam PF01926 50S ribosome-binding GTPase 7 121 4.2E-23 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 233 244 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 359 370 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PRINTS PR01041 Methionyl-tRNA synthetase signature 267 282 3.0E-33 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Gene3D G3DSA:3.40.50.620 2 113 4.3E-72 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Gene3D G3DSA:3.40.50.620 235 345 4.3E-72 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Gene3D G3DSA:2.40.50.140 555 664 2.6E-34 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Gene3D G3DSA:2.170.220.10 116 234 8.7E-47 T 23-04-2016 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PANTHER PTHR11946:SF1 2 620 3.6E-291 T 23-04-2016 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 490 5.7E-166 T 23-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Pfam PF09334 tRNA synthetases class I (M) 5 371 1.4E-111 T 23-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 539 664 1.0E-34 T 23-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Gene3D G3DSA:1.10.730.10 348 519 1.0E-51 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Pfam PF01588 Putative tRNA binding domain 568 662 1.6E-21 T 23-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 PANTHER PTHR11946 2 620 3.6E-291 T 23-04-2016 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 518 49.213 T 23-04-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 SUPERFAMILY SSF50249 558 664 2.94E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 SUPERFAMILY SSF47323 364 532 3.36E-42 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02080 dce5fed45d58c59de0de29865a3ae3e7 665 SUPERFAMILY SSF52374 2 358 9.38E-103 T 23-04-2016 SPYM18_RS05905 ad5ed80006cbea9cd1549d23e247e754 321 Pfam PF03631 Virulence factor BrkB 29 283 5.6E-50 T 23-04-2016 IPR017039 Virulence factor BrkB SPYM18_RS05905 ad5ed80006cbea9cd1549d23e247e754 321 PANTHER PTHR30213 4 283 1.4E-34 T 23-04-2016 SPYM18_RS05905 ad5ed80006cbea9cd1549d23e247e754 321 PIRSF PIRSF035875 1 302 7.6E-70 T 23-04-2016 IPR017039 Virulence factor BrkB SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 PANTHER PTHR13932:SF5 1 374 3.0E-152 T 23-04-2016 SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 PANTHER PTHR13932 1 374 3.0E-152 T 23-04-2016 SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 Pfam PF04055 Radical SAM superfamily 10 173 2.2E-21 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 SMART SM00729 5 221 4.1E-59 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 365 6.0E-115 T 23-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 Gene3D G3DSA:3.80.30.20 5 237 2.0E-39 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 Pfam PF06969 HemN C-terminal domain 300 364 1.3E-20 T 23-04-2016 IPR010723 HemN, C-terminal SPYM18_RS04425 452e4c9c2eba4d5324a4d7e6c402849d 376 SUPERFAMILY SSF102114 4 374 6.41E-116 T 23-04-2016 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 Pfam PF13377 Periplasmic binding protein-like domain 182 345 9.8E-32 T 23-04-2016 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 SMART SM00345 9 68 8.3E-22 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 68 4.5E-20 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 PANTHER PTHR30146 84 345 1.4E-42 T 23-04-2016 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 Gene3D G3DSA:3.40.50.2300 182 345 6.1E-41 T 23-04-2016 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 Gene3D G3DSA:1.10.10.10 4 73 5.6E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 7.7E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 7.7E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 SUPERFAMILY SSF53822 84 337 7.92E-44 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 PANTHER PTHR30146:SF30 84 345 1.4E-42 T 23-04-2016 SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 SUPERFAMILY SSF46785 5 72 1.4E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06915 454287c37efd9a66c5c992be1b4dbd96 346 Gene3D G3DSA:3.40.50.2300 127 181 5.9E-11 T 23-04-2016 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 92 3.0E-42 T 23-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 5.0E-21 T 23-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 Gene3D G3DSA:3.30.110.60 1 96 2.4E-30 T 23-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 SMART SM01103 2 85 6.2E-36 T 23-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 PANTHER PTHR31846 1 85 8.9E-30 T 23-04-2016 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 94 1.5E-25 T 23-04-2016 IPR017924 RNA-binding protein YhbY GO:0003723 SPYM18_RS01410 e79264d34d4641b144fddaecacfc8e3e 102 SUPERFAMILY SSF75471 1 95 1.7E-27 T 23-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Gene3D G3DSA:1.10.730.10 444 563 2.1E-36 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 563 1.3E-159 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 SUPERFAMILY SSF47323 444 563 7.41E-33 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 SMART SM00836 450 563 3.7E-42 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PANTHER PTHR11956:SF1 1 563 3.5E-234 T 23-04-2016 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Pfam PF05746 DALR anticodon binding domain 450 563 1.6E-32 T 23-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 1.7E-20 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 1.7E-20 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 1.7E-20 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 1.7E-20 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 PANTHER PTHR11956 1 563 3.5E-234 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Gene3D G3DSA:3.40.50.620 107 443 6.1E-114 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 SUPERFAMILY SSF52374 109 444 2.61E-97 T 23-04-2016 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 4 83 5.8E-19 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 SMART SM01016 1 83 6.6E-28 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 563 27.4 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 SUPERFAMILY SSF55190 1 103 2.22E-26 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Pfam PF00750 tRNA synthetases class I (R) 95 435 7.2E-100 T 23-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS09345 ab6da0a0b5d6d5167722faccd209fe01 563 Gene3D G3DSA:3.30.1360.70 3 98 3.9E-31 T 23-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 SUPERFAMILY SSF47928 6 102 2.62E-17 T 23-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 10 177 1.0E-35 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 PANTHER PTHR11910 12 178 2.1E-26 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 4.7E-19 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 PRINTS PR00125 ATP synthase delta subunit signature 8 27 4.7E-19 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 PRINTS PR00125 ATP synthase delta subunit signature 152 170 4.7E-19 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 PRINTS PR00125 ATP synthase delta subunit signature 137 152 4.7E-19 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 178 14.951 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 10 175 2.7E-27 T 23-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 SPYM18_RS03525 14e4184c6d2eb1e36ea981c202de66a9 178 Gene3D G3DSA:1.10.520.20 9 95 1.5E-13 T 23-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain SPYM18_RS06340 a44aa60fcbdb281883dc3ee4e0c88972 153 SUPERFAMILY SSF58050 29 72 3.27E-5 T 23-04-2016 IPR032038 Adenomatous polyposis coli, N-terminal dimerisation domain SPYM18_RS06340 a44aa60fcbdb281883dc3ee4e0c88972 153 Pfam PF14265 Domain of unknown function (DUF4355) 8 117 4.3E-7 T 23-04-2016 IPR025580 Protein of unknown function DUF4355 SPYM18_RS06340 a44aa60fcbdb281883dc3ee4e0c88972 153 Gene3D G3DSA:1.20.5.10 30 71 1.6E-4 T 23-04-2016 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 SUPERFAMILY SSF55486 51 592 5.49E-88 T 23-04-2016 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 Pfam PF08439 Oligopeptidase F 140 176 1.8E-6 T 23-04-2016 IPR013647 Oligopeptidase F, N-terminal domain SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 6 591 1.1E-193 T 23-04-2016 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 Pfam PF01432 Peptidase family M3 199 579 6.8E-37 T 23-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 PANTHER PTHR11804 23 599 4.1E-244 T 23-04-2016 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 PANTHER PTHR11804:SF45 23 599 4.1E-244 T 23-04-2016 SPYM18_RS02885 c85a88644353ee7411ea0d99a3c11e13 599 Gene3D G3DSA:3.40.390.10 376 420 2.7E-7 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 PANTHER PTHR21015 4 357 3.0E-152 T 23-04-2016 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 5 144 9.3E-39 T 23-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 Gene3D G3DSA:3.40.50.2000 195 335 1.1E-29 T 23-04-2016 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 5 356 23.427 T 23-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 PANTHER PTHR21015:SF27 4 357 3.0E-152 T 23-04-2016 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 Gene3D G3DSA:3.40.50.2000 1 194 1.1E-53 T 23-04-2016 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 SUPERFAMILY SSF53756 3 343 3.14E-77 T 23-04-2016 SPYM18_RS06635 64691f48affd7fb62febc48fe8b1ffa0 360 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 191 337 9.2E-24 T 23-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 SUPERFAMILY SSF52540 3 205 1.34E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 198 3.5E-54 T 23-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 PANTHER PTHR10344 4 209 7.1E-65 T 23-04-2016 SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 Gene3D G3DSA:3.40.50.300 4 207 2.0E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 Pfam PF02223 Thymidylate kinase 9 198 1.4E-48 T 23-04-2016 SPYM18_RS02020 6799e719ec1cde8fcfd45f5006427bcd 211 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 30.001 T 23-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 PANTHER PTHR23508 6 388 6.6E-67 T 23-04-2016 SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 Gene3D G3DSA:1.20.1250.20 219 395 1.4E-22 T 23-04-2016 SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 PANTHER PTHR23508:SF18 6 388 6.6E-67 T 23-04-2016 SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 SUPERFAMILY SSF103473 10 399 1.16E-72 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 Pfam PF07690 Major Facilitator Superfamily 25 280 3.4E-37 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS05865 035d02f25e9c48683c611d557c6ece13 406 Gene3D G3DSA:1.20.1250.20 12 200 4.7E-32 T 23-04-2016 SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 Gene3D G3DSA:1.10.8.100 214 287 9.4E-22 T 23-04-2016 IPR023165 rRNA adenine dimethylase-like SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 SUPERFAMILY SSF53335 15 287 7.04E-76 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 50 77 - T 23-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 Gene3D G3DSA:3.40.50.150 3 211 2.4E-74 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 PANTHER PTHR11727 1 289 3.8E-94 T 23-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 SMART SM00650 34 210 3.8E-87 T 23-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 18 286 55.511 T 23-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 250 1.3E-67 T 23-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm SPYM18_RS01210 c7f745b2de6192894b6100d6fe10f923 290 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 284 1.2E-82 T 23-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 PANTHER PTHR24220 7 231 2.1E-53 T 23-04-2016 SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 Gene3D G3DSA:3.40.50.300 2 231 1.4E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 Pfam PF00005 ABC transporter 31 174 1.4E-19 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 PANTHER PTHR24220:SF132 7 231 2.1E-53 T 23-04-2016 SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 SUPERFAMILY SSF52540 5 231 9.06E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08910 241a9c196919888fae59aa606e10231d 267 SMART SM00382 39 223 3.8E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Gene3D G3DSA:3.90.78.10 220 293 3.9E-31 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Pfam PF01565 FAD binding domain 29 158 1.3E-26 T 23-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 16 292 1.6E-67 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 PANTHER PTHR21071:SF4 1 295 5.9E-127 T 23-04-2016 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Gene3D G3DSA:3.30.43.10 4 81 3.2E-29 T 23-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 SUPERFAMILY SSF56194 188 293 4.05E-37 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 295 95.816 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 PANTHER PTHR21071 1 295 5.9E-127 T 23-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Gene3D G3DSA:3.30.465.10 82 219 3.0E-47 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 SUPERFAMILY SSF56176 5 187 8.0E-47 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SPYM18_RS04580 351f4b19a09ebb08b8980ce71f8aee7a 295 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 193 291 5.0E-27 T 23-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 PANTHER PTHR18919:SF95 1 394 4.0E-224 T 23-04-2016 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 PANTHER PTHR18919 1 394 4.0E-224 T 23-04-2016 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 2.7E-152 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Pfam PF02803 Thiolase, C-terminal domain 273 393 9.0E-52 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 SUPERFAMILY SSF53901 4 272 1.5E-91 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Gene3D G3DSA:3.40.47.10 143 194 8.1E-69 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Gene3D G3DSA:3.40.47.10 279 393 8.1E-69 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Gene3D G3DSA:3.40.47.10 195 278 9.9E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Gene3D G3DSA:3.40.47.10 4 124 9.9E-77 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 23-04-2016 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 SUPERFAMILY SSF53901 274 393 1.45E-44 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 PIRSF PIRSF000429 1 394 8.2E-139 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 23-04-2016 IPR020610 Thiolase, active site GO:0008152|GO:0016747 SPYM18_RS00800 012e17e2b209b36f7ccb1d6d818b7577 394 Pfam PF00108 Thiolase, N-terminal domain 5 265 1.3E-102 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Gene3D G3DSA:3.40.50.10490 444 604 1.4E-56 T 23-04-2016 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 604 37.797 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 SUPERFAMILY SSF53697 246 604 1.0E-89 T 23-04-2016 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 PANTHER PTHR10937:SF0 1 604 2.8E-271 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Pfam PF13522 Glutamine amidotransferase domain 63 189 1.1E-19 T 23-04-2016 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Gene3D G3DSA:3.60.20.10 2 235 8.7E-68 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Pfam PF01380 SIS domain 288 414 4.8E-27 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Pfam PF01380 SIS domain 460 585 2.7E-17 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 Gene3D G3DSA:3.40.50.10490 243 443 4.1E-50 T 23-04-2016 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 604 1.9E-208 T 23-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 SUPERFAMILY SSF56235 2 232 5.06E-63 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal SPYM18_RS05310 bf4910dbdbac1cbcd1ad770e2cca4693 604 PANTHER PTHR10937 1 604 2.8E-271 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 SMART SM00493 273 344 5.1E-16 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 SUPERFAMILY SSF57783 12 107 2.72E-32 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Pfam PF01807 CHC2 zinc finger 13 105 8.1E-36 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Gene3D G3DSA:3.90.580.10 12 105 1.9E-36 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Pfam PF08275 DNA primase catalytic core, N-terminal domain 136 266 3.0E-36 T 23-04-2016 IPR013264 DNA primase, catalytic core, N-terminal SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Gene3D G3DSA:3.40.1360.10 255 374 1.4E-41 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 PIRSF PIRSF002811 10 604 4.3E-168 T 23-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 PANTHER PTHR30313 10 570 6.1E-129 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Hamap MF_00974 DNA primase [dnaG]. 11 594 26.261 T 23-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Pfam PF13155 Toprim-like 276 358 1.6E-17 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Gene3D G3DSA:3.90.980.10 124 254 1.3E-37 T 23-04-2016 IPR013264 DNA primase, catalytic core, N-terminal SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 SUPERFAMILY SSF56731 124 436 1.83E-93 T 23-04-2016 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 Pfam PF10410 DnaB-helicase binding domain of primase 379 428 1.2E-4 T 23-04-2016 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 SMART SM00400 43 97 5.7E-31 T 23-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 SPYM18_RS03630 e9646d8ba64060678eec333416f8e7b2 604 TIGRFAM TIGR01391 dnaG: DNA primase 12 428 1.3E-136 T 23-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 SMART SM00363 185 247 2.5E-6 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 SUPERFAMILY SSF55174 40 130 5.5E-26 T 23-04-2016 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 SUPERFAMILY SSF55174 182 256 5.5E-26 T 23-04-2016 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 PANTHER PTHR32219 7 262 2.2E-52 T 23-04-2016 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 Gene3D G3DSA:3.10.290.10 184 239 4.7E-12 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06600 9667bb4d408d72b2ad2944a7f7228aa3 264 PANTHER PTHR32219:SF5 7 262 2.2E-52 T 23-04-2016 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 SUPERFAMILY SSF51344 3 87 6.8E-23 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 87 3.0E-33 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 PANTHER PTHR13822 1 135 3.9E-32 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 134 3.0E-29 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 85 1.5E-26 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 Gene3D G3DSA:2.60.15.10 3 92 3.3E-26 T 23-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 137 2.2E-15 T 23-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 135 22.583 T 23-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03545 fea57041abf867f9ef6d7817b69815bd 138 Gene3D G3DSA:1.20.5.440 93 137 1.1E-13 T 23-04-2016 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 PANTHER PTHR21090 1 419 5.6E-170 T 23-04-2016 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 41.134 T 23-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 Gene3D G3DSA:3.65.10.10 222 416 7.8E-59 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 415 6.9E-153 T 23-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 7.4E-86 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 Gene3D G3DSA:3.65.10.10 21 221 1.5E-59 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS05930 f4678cac527bfcee6ce36e94b3793e42 419 SUPERFAMILY SSF55205 1 418 3.6E-131 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 PANTHER PTHR11935:SF8 3 210 1.3E-48 T 23-04-2016 SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 PANTHER PTHR11935 3 210 1.3E-48 T 23-04-2016 SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 SUPERFAMILY SSF56281 10 211 8.12E-45 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 Pfam PF00753 Metallo-beta-lactamase superfamily 13 194 2.4E-28 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 SMART SM00849 12 194 3.4E-36 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS03025 e876e9b593a000f3ce0853e2e214ad68 211 Gene3D G3DSA:3.60.15.10 12 211 7.7E-43 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 Gene3D G3DSA:2.10.109.10 150 195 4.2E-28 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 Gene3D G3DSA:2.10.109.10 22 83 4.2E-28 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 PANTHER PTHR12383 1 194 3.9E-47 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 ProSitePatterns PS00760 Signal peptidases I lysine active site. 75 87 - T 23-04-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 SUPERFAMILY SSF51306 22 196 3.01E-46 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 Pfam PF00717 Peptidase S24-like 30 97 4.8E-18 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 191 1.3E-41 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 ProSitePatterns PS00501 Signal peptidases I serine active site. 33 40 - T 23-04-2016 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: REACT_15380 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 24 40 8.9E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 150 169 8.9E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 73 85 8.9E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS08225 dd890c4889aa10d1b391dd0c3a4cc659 197 PANTHER PTHR12383:SF14 1 194 3.9E-47 T 23-04-2016 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:3.30.1360.120 3 128 3.4E-46 T 23-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:3.40.50.300 224 255 1.6E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Pfam PF01926 50S ribosome-binding GTPase 228 339 1.8E-26 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 PANTHER PTHR11649 11 458 3.4E-163 T 23-04-2016 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 SUPERFAMILY SSF52540 83 170 6.9E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 SUPERFAMILY SSF52540 205 373 6.9E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 458 33.988 T 23-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:3.40.50.300 294 382 3.7E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Pfam PF10396 GTP-binding protein TrmE N-terminus 9 127 5.8E-41 T 23-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:1.20.120.430 256 279 1.5E-54 T 23-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:1.20.120.430 129 189 1.5E-54 T 23-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Gene3D G3DSA:1.20.120.430 388 458 1.5E-54 T 23-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 458 1.7E-130 T 23-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 228 367 1.4E-26 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 Pfam PF12631 MnmE helical domain 130 455 1.3E-56 T 23-04-2016 IPR025867 MnmE, helical domain SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 PANTHER PTHR11649:SF56 11 458 3.4E-163 T 23-04-2016 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 SUPERFAMILY SSF116878 383 458 1.31E-48 T 23-04-2016 SPYM18_RS04520 aaaaf59fda7a5f6e9c668052d6ac4d81 458 SUPERFAMILY SSF116878 129 228 1.31E-48 T 23-04-2016 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 PANTHER PTHR32308 1 293 2.1E-102 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 6 224 1.6E-82 T 23-04-2016 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 TIGRFAM TIGR01588 citE: citrate (pro-3S)-lyase, beta subunit 3 289 2.6E-142 T 23-04-2016 IPR006475 Citrate lyase, beta subunit, bacteria GO:0005737|GO:0006084|GO:0008816|GO:0009346 KEGG: 00720+4.1.3.34|MetaCyc: PWY-5392|MetaCyc: PWY-6038 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 SUPERFAMILY SSF51621 2 235 1.41E-64 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 PANTHER PTHR32308:SF0 1 293 2.1E-102 T 23-04-2016 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 Gene3D G3DSA:3.20.20.60 2 235 6.5E-73 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS04930 3ee3abc24d3d8e572030dffd7a1b5f97 295 PIRSF PIRSF015582 1 294 1.7E-83 T 23-04-2016 IPR011206 Citrate lyase beta subunit-like SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 SUPERFAMILY SSF48592 6 133 4.16E-78 T 23-04-2016 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 SUPERFAMILY SSF48592 404 518 4.16E-78 T 23-04-2016 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 Gene3D G3DSA:3.50.7.10 195 365 5.0E-95 T 23-04-2016 IPR027409 GroEL-like apical domain SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 3.9E-251 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 1.3E-102 T 23-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PANTHER PTHR11353 1 543 1.7E-232 T 23-04-2016 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 23-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 Hamap MF_00600 60 kDa chaperonin [groL]. 1 543 40.722 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 Gene3D G3DSA:1.10.560.10 366 515 1.3E-43 T 23-04-2016 IPR027413 GroEL-like equatorial domain SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 SUPERFAMILY SSF52029 182 374 8.07E-84 T 23-04-2016 IPR027409 GroEL-like apical domain SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 SUPERFAMILY SSF54849 136 204 3.2E-26 T 23-04-2016 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PRINTS PR00298 60kDa chaperonin signature 82 109 7.4E-74 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PRINTS PR00298 60kDa chaperonin signature 396 417 7.4E-74 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PRINTS PR00298 60kDa chaperonin signature 348 373 7.4E-74 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PRINTS PR00298 60kDa chaperonin signature 266 289 7.4E-74 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 PRINTS PR00298 60kDa chaperonin signature 26 52 7.4E-74 T 23-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 SPYM18_RS09115 e7899faeaeb3f47499d978ea9487c8c5 543 Gene3D G3DSA:1.10.560.10 3 194 5.4E-47 T 23-04-2016 IPR027413 GroEL-like equatorial domain SPYM18_RS02315 92840474be6461e3e9dbdbb84d4ea7fd 56 Gene3D G3DSA:3.30.420.10 2 55 1.3E-7 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02315 92840474be6461e3e9dbdbb84d4ea7fd 56 PANTHER PTHR32552 1 55 1.0E-11 T 23-04-2016 SPYM18_RS02315 92840474be6461e3e9dbdbb84d4ea7fd 56 SUPERFAMILY SSF53098 3 56 1.67E-12 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02315 92840474be6461e3e9dbdbb84d4ea7fd 56 Pfam PF00665 Integrase core domain 2 55 3.7E-11 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Gene3D G3DSA:3.40.1190.10 107 331 5.2E-53 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 35 472 2.2E-93 T 23-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 413 4.3E-16 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Gene3D G3DSA:3.90.190.20 332 470 6.3E-36 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Gene3D G3DSA:3.40.1390.10 33 106 4.4E-8 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 PANTHER PTHR23135 22 470 1.9E-124 T 23-04-2016 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 481 27.693 T 23-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 SUPERFAMILY SSF53244 328 474 1.09E-31 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 PANTHER PTHR23135:SF4 22 470 1.9E-124 T 23-04-2016 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 SUPERFAMILY SSF63418 15 107 2.35E-16 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 SUPERFAMILY SSF53623 78 339 4.97E-49 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01995 a5ad4d1e5968cc76d98d9106cf9b872c 481 Pfam PF08245 Mur ligase middle domain 117 308 1.1E-32 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 PANTHER PTHR10245 94 200 5.2E-18 T 23-04-2016 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 SUPERFAMILY SSF51306 122 240 1.96E-23 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 Pfam PF00717 Peptidase S24-like 161 221 5.8E-13 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 PANTHER PTHR10245 1 76 5.2E-18 T 23-04-2016 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 Gene3D G3DSA:2.10.109.10 127 240 2.5E-16 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 SMART SM00530 4 59 2.5E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 PANTHER PTHR10245:SF32 94 200 5.2E-18 T 23-04-2016 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 Gene3D G3DSA:1.10.260.40 1 68 4.0E-20 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 PANTHER PTHR10245:SF32 1 76 5.2E-18 T 23-04-2016 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 SUPERFAMILY SSF47413 1 63 9.12E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03075 b9485dea23a5bfefa6d56ed6ee527a9b 245 Pfam PF01381 Helix-turn-helix 5 59 1.4E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 SUPERFAMILY SSF50814 328 515 3.34E-78 T 23-04-2016 IPR011038 Calycin-like SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 SUPERFAMILY SSF53807 30 315 8.83E-83 T 23-04-2016 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PANTHER PTHR30477 1 354 1.2E-97 T 23-04-2016 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 Pfam PF01297 Zinc-uptake complex component A periplasmic 34 315 3.1E-79 T 23-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00691 Adhesin B signature 56 74 1.1E-10 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00691 Adhesin B signature 298 316 1.1E-10 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00691 Adhesin B signature 75 94 1.1E-10 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00691 Adhesin B signature 31 52 1.1E-10 T 23-04-2016 IPR006129 Adhesin B GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PANTHER PTHR30477:SF10 1 354 1.2E-97 T 23-04-2016 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00690 Adhesin family signature 258 276 1.1E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00690 Adhesin family signature 31 49 1.1E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00690 Adhesin family signature 62 75 1.1E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 PRINTS PR00690 Adhesin family signature 205 226 1.1E-10 T 23-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 Gene3D G3DSA:3.40.50.1980 199 315 4.7E-38 T 23-04-2016 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 Gene3D G3DSA:2.40.128.20 329 515 3.6E-83 T 23-04-2016 IPR012674 Calycin SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 Gene3D G3DSA:3.40.50.1980 28 198 9.1E-53 T 23-04-2016 SPYM18_RS03365 d145fc39de33048912026c9a068a4bf1 515 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 333 515 1.2E-82 T 23-04-2016 IPR015304 ZinT domain GO:0008270 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 636 5.1E-160 T 23-04-2016 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 SUPERFAMILY SSF56601 221 243 8.36E-86 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 SUPERFAMILY SSF56601 276 652 8.36E-86 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 Pfam PF00912 Transglycosylase 63 239 8.6E-61 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 PANTHER PTHR32282 5 565 2.0E-186 T 23-04-2016 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 PANTHER PTHR32282 588 652 2.0E-186 T 23-04-2016 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 Gene3D G3DSA:3.40.710.10 242 652 1.5E-87 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 Gene3D G3DSA:1.10.3810.10 63 241 1.2E-67 T 23-04-2016 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 Pfam PF00905 Penicillin binding protein transpeptidase domain 335 605 2.1E-33 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 SUPERFAMILY SSF53955 53 265 2.67E-67 T 23-04-2016 IPR023346 Lysozyme-like domain SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 PANTHER PTHR32282:SF0 5 565 2.0E-186 T 23-04-2016 SPYM18_RS07160 332e757863a45a513640fa7d06389282 721 PANTHER PTHR32282:SF0 588 652 2.0E-186 T 23-04-2016 SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 Pfam PF00364 Biotin-requiring enzyme 50 114 6.4E-17 T 23-04-2016 IPR000089 Biotin/lipoyl attachment SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 Gene3D G3DSA:2.40.50.100 47 115 2.1E-23 T 23-04-2016 SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 SUPERFAMILY SSF51230 41 115 1.57E-21 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 73 90 - T 23-04-2016 IPR001882 Biotin-binding site SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 PANTHER PTHR18866 5 116 1.1E-14 T 23-04-2016 SPYM18_RS04880 ff44e6bf354e8d9d912358e425cb5190 116 PANTHER PTHR18866:SF102 5 116 1.1E-14 T 23-04-2016 SPYM18_RS05460 425c6131a4482980fa272444bb871a68 121 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 14 121 4.7E-21 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPYM18_RS05460 425c6131a4482980fa272444bb871a68 121 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 20 91 6.0E-8 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 SMART SM00738 6 117 1.3E-46 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 177 2.0E-45 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 Gene3D G3DSA:3.30.70.940 7 119 1.0E-42 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 1.1E-6 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 1.1E-6 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 SMART SM00739 127 154 4.2E-6 T 23-04-2016 IPR005824 KOW SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 Gene3D G3DSA:2.30.30.30 124 178 1.7E-15 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 Pfam PF02357 Transcription termination factor nusG 7 114 9.3E-27 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 179 20.813 T 23-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 SUPERFAMILY SSF82679 7 118 1.96E-35 T 23-04-2016 IPR006645 NusG, N-terminal GO:0006355 SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 Pfam PF00467 KOW motif 130 157 3.3E-7 T 23-04-2016 IPR005824 KOW SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 SUPERFAMILY SSF50104 117 177 2.49E-11 T 23-04-2016 IPR008991 Translation protein SH3-like domain SPYM18_RS00895 c963ca8c251846718952900a20ae0038 179 PANTHER PTHR30265 2 179 7.5E-60 T 23-04-2016 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 PANTHER PTHR37038 2 71 3.6E-22 T 23-04-2016 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 SMART SM00530 7 61 1.2E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 PANTHER PTHR37038:SF1 2 71 3.6E-22 T 23-04-2016 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 Gene3D G3DSA:1.10.260.40 2 67 3.6E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 Pfam PF12844 Helix-turn-helix domain 5 63 1.0E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS09110 40649972fdbfb7e65b1ba0115b771cc6 81 SUPERFAMILY SSF47413 3 63 1.5E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 ProSitePatterns PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 167 190 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 SUPERFAMILY SSF50203 31 137 3.4E-39 T 23-04-2016 IPR008992 Enterotoxin GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR01898 Bacterial superantigen superfamily signature 231 247 5.9E-28 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR01898 Bacterial superantigen superfamily signature 180 194 5.9E-28 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR01898 Bacterial superantigen superfamily signature 126 139 5.9E-28 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR01898 Bacterial superantigen superfamily signature 167 180 5.9E-28 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR01898 Bacterial superantigen superfamily signature 91 117 5.9E-28 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 Gene3D G3DSA:2.40.50.110 59 122 8.8E-32 T 23-04-2016 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 Pfam PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain 54 135 8.2E-15 T 23-04-2016 IPR006173 Staphylococcal/Streptococcal toxin, OB-fold GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 SUPERFAMILY SSF54334 139 251 1.7E-36 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 ProSitePatterns PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. 130 139 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR00279 Bacterial toxin signature 167 183 4.7E-11 T 23-04-2016 IPR006177 Staphylococcal/streptococcal toxin, bacterial GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 PRINTS PR00279 Bacterial toxin signature 128 140 4.7E-11 T 23-04-2016 IPR006177 Staphylococcal/streptococcal toxin, bacterial GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 Gene3D G3DSA:3.10.20.120 123 245 2.2E-53 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS01810 e58074f69103d3cf0871db683d2ed194 251 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 145 248 1.6E-26 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 Gene3D G3DSA:3.90.1150.10 245 378 1.5E-45 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 SUPERFAMILY SSF53383 15 377 5.38E-108 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 Gene3D G3DSA:3.40.640.10 3 244 2.4E-84 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 PANTHER PTHR11808 5 378 1.5E-167 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 377 1.7E-136 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 SPYM18_RS00930 3b8b201e98ebb0cde6f1238c06205c66 379 PIRSF PIRSF001434 1 379 1.3E-134 T 23-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 SPYM18_RS01450 bd47f1d20bc19bffa27769df2ee65b59 281 PIRSF PIRSF002854 1 281 1.1E-78 T 23-04-2016 IPR004872 Lipoprotein NlpA family SPYM18_RS01450 bd47f1d20bc19bffa27769df2ee65b59 281 Pfam PF03180 NLPA lipoprotein 32 281 3.1E-91 T 23-04-2016 IPR004872 Lipoprotein NlpA family SPYM18_RS01450 bd47f1d20bc19bffa27769df2ee65b59 281 SUPERFAMILY SSF53850 31 281 6.04E-72 T 23-04-2016 SPYM18_RS01450 bd47f1d20bc19bffa27769df2ee65b59 281 Gene3D G3DSA:3.40.190.10 29 165 1.5E-49 T 23-04-2016 SPYM18_RS01450 bd47f1d20bc19bffa27769df2ee65b59 281 PANTHER PTHR30429 3 281 1.2E-80 T 23-04-2016 IPR004872 Lipoprotein NlpA family SPYM18_RS01615 654f05c47f4de3d564a473c6c1982688 147 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 2 144 1.4E-48 T 23-04-2016 IPR010024 Conserved hypothetical protein CHP1671 SPYM18_RS01615 654f05c47f4de3d564a473c6c1982688 147 Gene3D G3DSA:2.30.30.290 63 146 1.6E-16 T 23-04-2016 IPR023385 YopX-like domain, beta barrel type SPYM18_RS01615 654f05c47f4de3d564a473c6c1982688 147 Pfam PF09643 YopX protein 4 143 2.9E-25 T 23-04-2016 IPR019096 YopX protein SPYM18_RS01615 654f05c47f4de3d564a473c6c1982688 147 SUPERFAMILY SSF159006 1 146 1.83E-33 T 23-04-2016 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 23-04-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 PANTHER PTHR11659:SF0 2 479 3.1E-244 T 23-04-2016 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 2.5E-165 T 23-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 37.162 T 23-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 SUPERFAMILY SSF55931 4 295 7.19E-118 T 23-04-2016 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 PANTHER PTHR11659 2 479 3.1E-244 T 23-04-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 SUPERFAMILY SSF89095 297 401 5.89E-32 T 23-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 SMART SM00845 327 474 2.2E-64 T 23-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 Pfam PF02637 GatB domain 327 474 9.3E-47 T 23-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 SPYM18_RS07955 c8c351d83355affe6470ae40ed8d6796 479 Pfam PF02934 GatB/GatE catalytic domain 6 288 1.1E-108 T 23-04-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 4.1E-60 T 23-04-2016 IPR003797 DegV SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 Gene3D G3DSA:2.20.28.50 30 66 3.3E-10 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 PANTHER PTHR33434 1 274 1.3E-69 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 PANTHER PTHR33434:SF3 1 274 1.3E-69 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 Gene3D G3DSA:3.40.50.10440 67 153 2.9E-32 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 Gene3D G3DSA:3.40.50.10440 1 29 2.9E-32 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 272 8.6E-74 T 23-04-2016 IPR003797 DegV SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 Gene3D G3DSA:3.30.1180.10 154 278 3.6E-36 T 23-04-2016 SPYM18_RS07340 e0e4dcb4020e0020ce12720e91a050c0 280 SUPERFAMILY SSF82549 1 279 2.22E-67 T 23-04-2016 SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 PANTHER PTHR32282 15 719 5.1E-170 T 23-04-2016 SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 Gene3D G3DSA:3.40.710.10 338 727 1.4E-80 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 SUPERFAMILY SSF53955 79 302 1.15E-57 T 23-04-2016 IPR023346 Lysozyme-like domain SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 Pfam PF00912 Transglycosylase 90 277 4.9E-50 T 23-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 Gene3D G3DSA:1.10.3810.10 99 292 1.5E-56 T 23-04-2016 SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 PANTHER PTHR32282:SF5 15 719 5.1E-170 T 23-04-2016 SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 SUPERFAMILY SSF56601 335 760 8.88E-92 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 SUPERFAMILY SSF56601 262 281 8.88E-92 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS00625 cee67670f32ca518682d6f1efbcd9168 766 Pfam PF00905 Penicillin binding protein transpeptidase domain 399 634 1.3E-21 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPYM18_RS02810 dd7a8a26e82d2a87c660f5d29499fa1d 142 Gene3D G3DSA:3.40.50.150 44 126 7.7E-4 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS02810 dd7a8a26e82d2a87c660f5d29499fa1d 142 Pfam PF12732 YtxH-like protein 6 108 1.3E-11 T 23-04-2016 IPR024623 Uncharacterised protein family YtxH SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 SUPERFAMILY SSF111331 6 302 1.0E-72 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 298 2.2E-72 T 23-04-2016 IPR005218 Diacylglycerol/lipid kinase SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 Gene3D G3DSA:3.40.50.10330 33 97 3.8E-5 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 PANTHER PTHR12358:SF41 4 313 4.1E-122 T 23-04-2016 SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 131 4.6E-33 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 PANTHER PTHR12358 4 313 4.1E-122 T 23-04-2016 SPYM18_RS03505 864b144963319808fb3a09850ded48e5 340 SMART SM00046 6 130 1.4E-5 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPYM18_RS09465 bbed1679844236886f6568f369a5cbf4 177 PANTHER PTHR30055:SF55 4 174 6.0E-35 T 23-04-2016 SPYM18_RS09465 bbed1679844236886f6568f369a5cbf4 177 Gene3D G3DSA:1.10.357.10 4 175 2.8E-20 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SPYM18_RS09465 bbed1679844236886f6568f369a5cbf4 177 SUPERFAMILY SSF46689 4 67 1.23E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS09465 bbed1679844236886f6568f369a5cbf4 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 8.8E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPYM18_RS09465 bbed1679844236886f6568f369a5cbf4 177 PANTHER PTHR30055 4 174 6.0E-35 T 23-04-2016 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.0E-44 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 SUPERFAMILY SSF54999 5 102 3.27E-36 T 23-04-2016 IPR027486 Ribosomal protein S10 domain SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 23-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.403 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 5.7E-19 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.7E-19 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 5.7E-19 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 SMART SM01403 7 101 7.5E-55 T 23-04-2016 IPR027486 Ribosomal protein S10 domain SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 1.2E-34 T 23-04-2016 IPR027486 Ribosomal protein S10 domain SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 Gene3D G3DSA:3.30.70.600 3 102 1.9E-42 T 23-04-2016 IPR027486 Ribosomal protein S10 domain SPYM18_RS00365 ebd17b0c369b87c103cc7baed0014014 102 PANTHER PTHR11700 1 102 5.8E-48 T 23-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 60 705 1.3E-184 T 23-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SMART SM00955 252 581 4.7E-173 T 23-04-2016 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 Pfam PF00575 S1 RNA binding domain 627 705 1.4E-15 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 Pfam PF00773 RNB domain 252 578 6.2E-117 T 23-04-2016 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SUPERFAMILY SSF50249 628 705 2.09E-18 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SUPERFAMILY SSF50249 126 227 1.54E-5 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SMART SM00316 626 707 5.7E-16 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SUPERFAMILY SSF50249 213 625 2.06E-139 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 707 6.9E-244 T 23-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 Hamap MF_01895 Ribonuclease R [rnr]. 18 707 54.846 T 23-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 Gene3D G3DSA:2.40.50.140 628 706 4.2E-19 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 PANTHER PTHR23355:SF9 70 775 2.0E-229 T 23-04-2016 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 PANTHER PTHR23355 70 775 2.0E-229 T 23-04-2016 SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 SUPERFAMILY SSF50249 65 134 4.57E-10 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 Pfam PF08206 Ribonuclease B OB domain 72 129 2.9E-16 T 23-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain SPYM18_RS02425 5faa361e385e913ac7253746420a7ce7 776 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 23-04-2016 IPR022966 Ribonuclease II/R, conserved site SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 PANTHER PTHR30175:SF7 1 577 1.1E-239 T 23-04-2016 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 Gene3D G3DSA:2.70.70.10 479 626 1.5E-59 T 23-04-2016 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 PANTHER PTHR30175 1 577 1.1E-239 T 23-04-2016 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 482 602 3.1E-43 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 SUPERFAMILY SSF51261 479 625 5.23E-52 T 23-04-2016 IPR011055 Duplicated hybrid motif SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 Pfam PF00367 phosphotransferase system, EIIB 9 41 1.2E-13 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 481 605 1.9E-49 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 Pfam PF02378 Phosphotransferase system, EIIC 109 399 9.9E-37 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 SUPERFAMILY SSF55604 6 79 1.44E-19 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 452 9.2E-188 T 23-04-2016 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 Gene3D G3DSA:3.30.1360.60 1 80 1.8E-25 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 544 556 - T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08110 e0ea572b7ca471454b6532440b2c49c8 627 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS06855 f4a4bed254c66003e9f0568362242d55 251 PANTHER PTHR10108 13 208 1.7E-37 T 23-04-2016 SPYM18_RS06855 f4a4bed254c66003e9f0568362242d55 251 Pfam PF13649 Methyltransferase domain 42 139 2.4E-20 T 23-04-2016 SPYM18_RS06855 f4a4bed254c66003e9f0568362242d55 251 PANTHER PTHR10108:SF805 13 208 1.7E-37 T 23-04-2016 SPYM18_RS06855 f4a4bed254c66003e9f0568362242d55 251 Gene3D G3DSA:3.40.50.150 16 241 1.3E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06855 f4a4bed254c66003e9f0568362242d55 251 SUPERFAMILY SSF53335 14 237 1.15E-40 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.255 T 23-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 SUPERFAMILY SSF50104 126 273 4.93E-58 T 23-04-2016 IPR008991 Translation protein SH3-like domain SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 PANTHER PTHR13691 3 276 1.5E-147 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 23-04-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.9E-35 T 23-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 6.3E-56 T 23-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 PIRSF PIRSF002158 5 276 2.2E-98 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Gene3D G3DSA:4.10.950.10 196 274 9.6E-34 T 23-04-2016 IPR014726 Ribosomal protein L2, domain 3 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 SMART SM01383 42 118 1.9E-46 T 23-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Gene3D G3DSA:2.30.30.30 118 195 4.6E-35 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 Gene3D G3DSA:2.40.50.140 2 114 2.6E-52 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 SUPERFAMILY SSF50249 3 125 8.23E-52 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 SMART SM01382 124 253 2.2E-88 T 23-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00385 91b1182c01d50b7cba1e635747b6ade4 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 1.8E-136 T 23-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 SPYM18_RS03975 4232593b088dcc87e2fecddaf6469061 126 PIRSF PIRSF031568 1 126 2.4E-63 T 23-04-2016 IPR009530 Protein of unknown function DUF1149 SPYM18_RS03975 4232593b088dcc87e2fecddaf6469061 126 Pfam PF06619 Protein of unknown function (DUF1149) 1 124 1.7E-49 T 23-04-2016 IPR009530 Protein of unknown function DUF1149 SPYM18_RS03975 4232593b088dcc87e2fecddaf6469061 126 Gene3D G3DSA:3.10.420.10 1 124 4.0E-54 T 23-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SPYM18_RS03975 4232593b088dcc87e2fecddaf6469061 126 SUPERFAMILY SSF54611 1 124 1.57E-50 T 23-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Pfam PF14579 Helix-hairpin-helix motif 730 812 2.7E-10 T 23-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Gene3D G3DSA:2.40.50.140 876 966 1.6E-9 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 243 659 4.7E-156 T 23-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 SUPERFAMILY SSF89550 9 81 3.92E-6 T 23-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 SMART SM00481 3 70 2.2E-6 T 23-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Pfam PF02811 PHP domain 7 115 1.7E-16 T 23-04-2016 IPR004013 PHP domain GO:0003824 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 157 927 1.2E-205 T 23-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 PANTHER PTHR32294 1 1036 0.0 T 23-04-2016 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 PANTHER PTHR32294:SF0 1 1036 0.0 T 23-04-2016 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Pfam PF01336 OB-fold nucleic acid binding domain 899 965 2.8E-9 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPYM18_RS05330 f0e32e932e444ef20f30f24e0ec30f47 1036 Gene3D G3DSA:3.20.20.140 9 88 9.8E-8 T 23-04-2016 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 SUPERFAMILY SSF55469 9 217 1.31E-48 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 Pfam PF00881 Nitroreductase family 15 199 3.6E-27 T 23-04-2016 IPR029479 Nitroreductase SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 PANTHER PTHR23026 131 221 7.6E-52 T 23-04-2016 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 PANTHER PTHR23026 5 113 7.6E-52 T 23-04-2016 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 PANTHER PTHR23026:SF101 131 221 7.6E-52 T 23-04-2016 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 PANTHER PTHR23026:SF101 5 113 7.6E-52 T 23-04-2016 SPYM18_RS02465 0490af46066a196801cde4646d1d44bc 221 Gene3D G3DSA:3.40.109.10 7 220 3.3E-64 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 445 537 1.8E-14 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 Pfam PF02378 Phosphotransferase system, EIIC 19 381 1.8E-55 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 7 553 0.0 T 23-04-2016 IPR011300 Phosphotransferase system, IIBC component KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 SUPERFAMILY SSF55604 478 551 3.01E-18 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 PANTHER PTHR30009 11 563 8.5E-299 T 23-04-2016 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 PANTHER PTHR30009:SF8 11 563 8.5E-299 T 23-04-2016 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 Pfam PF00367 phosphotransferase system, EIIB 480 511 1.6E-14 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 Gene3D G3DSA:2.70.70.10 576 726 2.2E-54 T 23-04-2016 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 SUPERFAMILY SSF51261 578 722 1.74E-48 T 23-04-2016 IPR011055 Duplicated hybrid motif SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 Gene3D G3DSA:3.30.1360.60 474 552 5.7E-25 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 490 507 - T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 581 705 5.6E-46 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 583 702 2.5E-39 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08830 13d85ef6a69d8ea7124a6a2742c09cf4 728 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 644 656 - T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 PANTHER PTHR30175:SF4 526 621 0.0 T 23-04-2016 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 PANTHER PTHR30175:SF4 1 509 0.0 T 23-04-2016 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 Gene3D G3DSA:3.30.1360.60 3 82 1.3E-25 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 SUPERFAMILY SSF55604 8 81 1.03E-20 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 525 649 3.7E-48 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 Pfam PF02378 Phosphotransferase system, EIIC 111 430 2.0E-36 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 526 646 8.5E-40 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 5 488 1.7E-231 T 23-04-2016 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 Pfam PF00367 phosphotransferase system, EIIB 10 42 1.2E-14 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 PANTHER PTHR30175 526 621 0.0 T 23-04-2016 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 PANTHER PTHR30175 1 509 0.0 T 23-04-2016 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 Gene3D G3DSA:2.70.70.10 519 672 2.8E-55 T 23-04-2016 SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 SUPERFAMILY SSF51261 517 670 2.96E-50 T 23-04-2016 IPR011055 Duplicated hybrid motif SPYM18_RS09230 dd6bb5fa268f982121708d3dd5231548 674 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 588 600 - T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS04820 d978ca45cd1a9184142282d392482457 137 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 135 7.9E-17 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPYM18_RS04820 d978ca45cd1a9184142282d392482457 137 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 23-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 SPYM18_RS04820 d978ca45cd1a9184142282d392482457 137 SUPERFAMILY SSF54593 1 137 1.06E-26 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS04820 d978ca45cd1a9184142282d392482457 137 Gene3D G3DSA:3.10.180.10 8 137 6.9E-33 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 1.9E-25 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 SMART SM00739 2 29 6.4E-6 T 23-04-2016 IPR005824 KOW SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 99 1.1E-34 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 PANTHER PTHR12903 1 101 4.0E-42 T 23-04-2016 SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 23-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 Gene3D G3DSA:2.30.30.30 1 89 6.3E-21 T 23-04-2016 IPR014722 Ribosomal protein L2 domain 2 SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 SUPERFAMILY SSF50104 2 99 3.57E-31 T 23-04-2016 IPR008991 Translation protein SH3-like domain SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 Pfam PF00467 KOW motif 5 36 1.7E-7 T 23-04-2016 IPR005824 KOW SPYM18_RS00425 9d2f8eb37ef949d5c2a19c324c1c932d 101 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 94 19.913 T 23-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05745 93757c7bdf762186fc9f2d407caa8a9a 418 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 12 408 2.4E-160 T 23-04-2016 IPR024024 D-alanyl transfer protein DltB UniPathway: UPA00556 SPYM18_RS05745 93757c7bdf762186fc9f2d407caa8a9a 418 PANTHER PTHR13285 2 409 4.4E-54 T 23-04-2016 SPYM18_RS05745 93757c7bdf762186fc9f2d407caa8a9a 418 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 65 365 1.0E-15 T 23-04-2016 IPR004299 Membrane bound O-acyl transferase, MBOAT SPYM18_RS05745 93757c7bdf762186fc9f2d407caa8a9a 418 PIRSF PIRSF500216 10 413 8.6E-175 T 23-04-2016 IPR024024 D-alanyl transfer protein DltB UniPathway: UPA00556 SPYM18_RS05745 93757c7bdf762186fc9f2d407caa8a9a 418 PIRSF PIRSF016636 14 408 1.6E-81 T 23-04-2016 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 40.724 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 TIGRFAM TIGR00502 nagB: glucosamine-6-phosphate deaminase 1 233 5.5E-72 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 112 130 - T 23-04-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 Gene3D G3DSA:3.40.50.1360 1 233 4.6E-83 T 23-04-2016 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 SUPERFAMILY SSF100950 1 233 8.9E-82 T 23-04-2016 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 22 221 1.6E-14 T 23-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 SPYM18_RS06090 fd794d97db43fb29be317e66c3b10f0e 234 PANTHER PTHR11280 1 234 3.2E-93 T 23-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 PANTHER PTHR15004:SF0 1 94 6.0E-30 T 23-04-2016 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 SUPERFAMILY SSF141000 2 93 2.09E-27 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 94 1.7E-31 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 PANTHER PTHR15004 1 94 6.0E-30 T 23-04-2016 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 23.354 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPYM18_RS07965 b2f35f1cd96492e045e79e3ad685662e 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 8.8E-17 T 23-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 SPYM18_RS06910 444097c1133b79e719ba5063e310433e 564 Pfam PF07555 beta-N-acetylglucosaminidase 132 437 1.5E-98 T 23-04-2016 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 SPYM18_RS06910 444097c1133b79e719ba5063e310433e 564 PANTHER PTHR13170:SF20 72 393 1.4E-76 T 23-04-2016 SPYM18_RS06910 444097c1133b79e719ba5063e310433e 564 SUPERFAMILY SSF51445 130 448 3.58E-99 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS06910 444097c1133b79e719ba5063e310433e 564 SUPERFAMILY SSF55545 35 127 4.34E-5 T 23-04-2016 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like SPYM18_RS06910 444097c1133b79e719ba5063e310433e 564 PANTHER PTHR13170 72 393 1.4E-76 T 23-04-2016 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 Pfam PF02926 THUMP domain 49 163 1.6E-13 T 23-04-2016 IPR004114 THUMP domain GO:0003723 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 371 8.9E-114 T 23-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 SMART SM00981 74 165 2.7E-15 T 23-04-2016 IPR004114 THUMP domain GO:0003723 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 Gene3D G3DSA:3.40.50.620 173 333 4.0E-49 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 404 160.441 T 23-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 SUPERFAMILY SSF52402 174 386 4.63E-49 T 23-04-2016 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 SUPERFAMILY SSF143437 3 173 9.42E-50 T 23-04-2016 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 PANTHER PTHR14911:SF16 1 400 2.0E-167 T 23-04-2016 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 370 2.4E-62 T 23-04-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 SPYM18_RS03785 70622257c3ed0e7ee64ddd08bc616217 404 PANTHER PTHR14911 1 400 2.0E-167 T 23-04-2016 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 324 65.172 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 Gene3D G3DSA:3.40.47.10 4 160 4.8E-56 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 PANTHER PTHR18919:SF109 27 323 9.1E-108 T 23-04-2016 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 PANTHER PTHR18919 27 323 9.1E-108 T 23-04-2016 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 SUPERFAMILY SSF53901 5 323 1.15E-62 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 Gene3D G3DSA:3.40.47.10 161 323 2.9E-48 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 324 6.0E-34 T 23-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 8.8E-31 T 23-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 SPYM18_RS07895 3e352f21b66112280efa2fdac9b57210 324 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 323 9.7E-100 T 23-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 SPYM18_RS03490 b2b647fc2e89d98146c960dea1be7956 910 SUPERFAMILY SSF56219 547 847 5.61E-33 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS03490 b2b647fc2e89d98146c960dea1be7956 910 PANTHER PTHR33607 283 851 1.2E-139 T 23-04-2016 SPYM18_RS03490 b2b647fc2e89d98146c960dea1be7956 910 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 552 843 2.9E-14 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS03490 b2b647fc2e89d98146c960dea1be7956 910 Gene3D G3DSA:3.60.10.10 549 850 6.9E-30 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS03490 b2b647fc2e89d98146c960dea1be7956 910 PANTHER PTHR33607:SF1 283 851 1.2E-139 T 23-04-2016 SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 Pfam PF05193 Peptidase M16 inactive domain 187 350 9.1E-25 T 23-04-2016 IPR007863 Peptidase M16, C-terminal SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 SUPERFAMILY SSF63411 6 213 3.33E-17 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 PANTHER PTHR11851 198 401 2.4E-15 T 23-04-2016 SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 SUPERFAMILY SSF63411 241 401 1.57E-28 T 23-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 Gene3D G3DSA:3.30.830.10 240 401 5.5E-29 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 SPYM18_RS09555 3aa471ddee031127ea68a8131268c10f 414 Gene3D G3DSA:3.30.830.10 1 226 1.2E-79 T 23-04-2016 IPR011237 Peptidase M16 domain GO:0046872 SPYM18_RS01125 590211b926169c6904db8d4a16e7d462 427 PANTHER PTHR40448 1 427 6.0E-32 T 23-04-2016 SPYM18_RS01125 590211b926169c6904db8d4a16e7d462 427 Pfam PF14501 GHKL domain 332 385 2.8E-6 T 23-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPYM18_RS01125 590211b926169c6904db8d4a16e7d462 427 PANTHER PTHR40448:SF1 1 427 6.0E-32 T 23-04-2016 SPYM18_RS03020 7aacbcf15a009331d56de809fc29edc8 309 Pfam PF02687 FtsX-like permease family 189 308 3.1E-14 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS03020 7aacbcf15a009331d56de809fc29edc8 309 PANTHER PTHR30489 3 68 2.6E-34 T 23-04-2016 SPYM18_RS03020 7aacbcf15a009331d56de809fc29edc8 309 PANTHER PTHR30489 84 309 2.6E-34 T 23-04-2016 SPYM18_RS03020 7aacbcf15a009331d56de809fc29edc8 309 PIRSF PIRSF003097 1 309 2.0E-75 T 23-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 SMART SM00382 38 150 1.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Gene3D G3DSA:1.20.272.10 233 330 3.5E-39 T 23-04-2016 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Gene3D G3DSA:3.40.50.300 6 140 9.6E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 1.6E-14 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 SUPERFAMILY SSF52540 5 218 1.75E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 SUPERFAMILY SSF48019 237 419 1.19E-66 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 416 2.3E-60 T 23-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Pfam PF16193 AAA C-terminal domain 174 251 4.2E-22 T 23-04-2016 IPR032423 AAA ATPase, C-terminal domain SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Gene3D G3DSA:1.10.8.60 141 212 1.2E-10 T 23-04-2016 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 PANTHER PTHR13779:SF7 5 404 7.2E-156 T 23-04-2016 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 PANTHER PTHR13779 5 404 7.2E-156 T 23-04-2016 SPYM18_RS08865 c5370a5f61bbf4e70ac6ccd1a3bfa929 422 Gene3D G3DSA:1.10.3710.10 331 420 3.3E-26 T 23-04-2016 SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 PANTHER PTHR24220 3 223 2.8E-83 T 23-04-2016 SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 SUPERFAMILY SSF52540 2 224 8.74E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 Pfam PF00005 ABC transporter 17 160 4.8E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 PANTHER PTHR24220:SF160 3 223 2.8E-83 T 23-04-2016 SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 SMART SM00382 26 211 2.6E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS07470 11796899a757d4fbcb8954e7ef58be6f 241 Gene3D G3DSA:3.40.50.300 1 226 2.1E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04345 0213374bd19ffc9b2f9dff9ca441e2ff 261 PANTHER PTHR10907 3 217 9.8E-35 T 23-04-2016 SPYM18_RS04345 0213374bd19ffc9b2f9dff9ca441e2ff 261 Pfam PF00756 Putative esterase 11 244 3.4E-23 T 23-04-2016 IPR000801 Putative esterase SPYM18_RS04345 0213374bd19ffc9b2f9dff9ca441e2ff 261 Gene3D G3DSA:3.40.50.1820 6 254 9.1E-57 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS04345 0213374bd19ffc9b2f9dff9ca441e2ff 261 SUPERFAMILY SSF53474 4 250 4.5E-46 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS04345 0213374bd19ffc9b2f9dff9ca441e2ff 261 PANTHER PTHR10907:SF33 3 217 9.8E-35 T 23-04-2016 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 PANTHER PTHR23416 5 180 1.3E-80 T 23-04-2016 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 Gene3D G3DSA:1.10.3130.10 5 61 2.6E-21 T 23-04-2016 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 165 6.0E-69 T 23-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 PANTHER PTHR23416:SF55 5 180 1.3E-80 T 23-04-2016 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 Gene3D G3DSA:2.160.10.10 62 184 5.5E-31 T 23-04-2016 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 SUPERFAMILY SSF51161 4 174 4.99E-50 T 23-04-2016 IPR011004 Trimeric LpxA-like SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 PIRSF PIRSF000441 2 192 2.3E-69 T 23-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 SPYM18_RS08675 17221d73b924687e03c471cc9ae73190 193 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 116 149 3.6E-4 T 23-04-2016 IPR001451 Hexapeptide repeat SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 SUPERFAMILY SSF51445 1 465 1.3E-157 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PANTHER PTHR10353 286 468 0.0 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PANTHER PTHR10353 1 263 0.0 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 TIGRFAM TIGR01233 lacG: 6-phospho-beta-galactosidase 2 468 1.1E-276 T 23-04-2016 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85|UniPathway: UPA00542 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PANTHER PTHR10353:SF62 286 468 0.0 T 23-04-2016 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PANTHER PTHR10353:SF62 1 263 0.0 T 23-04-2016 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 Hamap MF_01574 6-phospho-beta-galactosidase [lacG]. 1 468 66.147 T 23-04-2016 IPR005928 6-phospho-beta-galactosidase GO:0019512|GO:0033920 KEGG: 00052+3.2.1.85|UniPathway: UPA00542 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 402 3.8E-24 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 436 448 3.8E-24 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 3.8E-24 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 412 429 3.8E-24 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 PRINTS PR00131 Glycosyl hydrolase family 1 signature 371 379 3.8E-24 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 Gene3D G3DSA:3.20.20.80 3 466 9.2E-148 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 Pfam PF00232 Glycosyl hydrolase family 1 2 465 4.9E-167 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 371 379 - T 23-04-2016 IPR018120 Glycoside hydrolase family 1, active site SPYM18_RS08565 bc78ede10d998401b2d2bb510abc2e61 468 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 23-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPYM18_RS02785 d38b55558b9e9d7242bbaed0f06f684c 145 Pfam PF10263 SprT-like family 9 141 7.3E-21 T 23-04-2016 IPR006640 SprT-like SPYM18_RS02785 d38b55558b9e9d7242bbaed0f06f684c 145 SMART SM00731 1 142 9.9E-66 T 23-04-2016 IPR006640 SprT-like SPYM18_RS02785 d38b55558b9e9d7242bbaed0f06f684c 145 PANTHER PTHR41243 1 144 7.4E-63 T 23-04-2016 SPYM18_RS02785 d38b55558b9e9d7242bbaed0f06f684c 145 Hamap MF_00745 Protein SprT-like. 1 142 40.201 T 23-04-2016 IPR023524 Uncharacterised protein family SprT-like SPYM18_RS02785 d38b55558b9e9d7242bbaed0f06f684c 145 PANTHER PTHR41243:SF1 1 144 7.4E-63 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.1E-11 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.1E-11 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.1E-11 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.1E-11 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.1E-11 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 120 143 4.5E-9 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 239 261 4.5E-9 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PANTHER PTHR23115:SF69 1 181 5.3E-228 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PANTHER PTHR23115:SF69 239 486 5.3E-228 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Gene3D G3DSA:3.30.70.870 384 454 4.8E-15 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Pfam PF16658 Class II release factor RF3, C-terminal domain 377 501 3.0E-43 T 23-04-2016 IPR032090 Peptide chain release factor 3, C-terminal SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 153 3.2E-21 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PANTHER PTHR23115 1 181 5.3E-228 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 PANTHER PTHR23115 239 486 5.3E-228 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Gene3D G3DSA:2.40.30.10 283 383 7.2E-25 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 SUPERFAMILY SSF50447 249 379 1.06E-27 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 SUPERFAMILY SSF52540 6 265 2.95E-86 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Gene3D G3DSA:3.40.50.300 4 270 1.6E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Pfam PF03144 Elongation factor Tu domain 2 303 369 1.0E-11 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 514 49.912 T 23-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 SUPERFAMILY SSF54980 383 455 1.19E-16 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 Pfam PF00009 Elongation factor Tu GTP binding domain 9 265 3.1E-51 T 23-04-2016 SPYM18_RS06160 f397bd94e0f6f9a707b3d779b2a0697f 514 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 4 511 1.8E-197 T 23-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 16 31 - T 23-04-2016 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 Pfam PF01144 Coenzyme A transferase 6 214 2.1E-65 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 6 214 5.7E-71 T 23-04-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 SMART SM00882 4 215 7.2E-77 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 PANTHER PTHR13707 6 215 3.3E-94 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 SUPERFAMILY SSF100950 4 214 1.4E-78 T 23-04-2016 SPYM18_RS07110 cfc26fa986bda91bbbf7e634eeaf049f 216 Gene3D G3DSA:3.40.1080.10 5 214 4.1E-86 T 23-04-2016 SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 392 423 - T 23-04-2016 IPR030390 RNA methyltransferase TrmA, active site SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 444 454 - T 23-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 PANTHER PTHR11061 8 462 1.9E-149 T 23-04-2016 SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 Gene3D G3DSA:2.40.50.140 10 80 7.8E-21 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 Gene3D G3DSA:3.40.50.150 256 459 2.9E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 26 454 1.2E-128 T 23-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 Pfam PF01938 TRAM domain 18 68 2.7E-8 T 23-04-2016 IPR002792 TRAM domain SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 SUPERFAMILY SSF50249 6 68 8.57E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 SUPERFAMILY SSF53335 86 461 1.69E-72 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 PANTHER PTHR11061:SF30 8 462 1.9E-149 T 23-04-2016 SPYM18_RS05885 8ad6494895d39dd2d83e5a80c8968f2b 462 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 99 461 1.1E-24 T 23-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795:SF419 278 417 6.7E-59 T 23-04-2016 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795:SF419 461 690 6.7E-59 T 23-04-2016 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795:SF419 214 229 6.7E-59 T 23-04-2016 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795:SF419 135 164 6.7E-59 T 23-04-2016 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 279 289 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Gene3D G3DSA:3.40.50.200 129 209 6.8E-78 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Gene3D G3DSA:3.40.50.200 572 686 6.8E-78 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Gene3D G3DSA:3.40.50.200 275 429 6.8E-78 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 147 158 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795 278 417 6.7E-59 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795 461 690 6.7E-59 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795 214 229 6.7E-59 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PANTHER PTHR10795 135 164 6.7E-59 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 615 625 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 SUPERFAMILY SSF52025 461 555 1.31E-7 T 23-04-2016 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Pfam PF00082 Subtilase family 142 678 7.2E-50 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Pfam PF06280 Fn3-like domain 701 814 1.5E-26 T 23-04-2016 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PRINTS PR00723 Subtilisin serine protease family (S8) signature 275 288 1.2E-13 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 1.2E-13 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 PRINTS PR00723 Subtilisin serine protease family (S8) signature 614 630 1.2E-13 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Pfam PF04650 YSIRK type signal peptide 2 26 2.5E-10 T 23-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 SUPERFAMILY SSF52743 574 688 3.53E-60 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 SUPERFAMILY SSF52743 124 162 3.53E-60 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 SUPERFAMILY SSF52743 250 420 3.53E-60 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 2 35 1.4E-10 T 23-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Pfam PF02225 PA domain 475 547 3.5E-10 T 23-04-2016 IPR003137 PA domain SPYM18_RS02070 5f7651c3b983f052cd6e1ba9d1590668 1647 Gene3D G3DSA:3.50.30.30 460 561 3.9E-19 T 23-04-2016 SPYM18_RS05965 05b50579ba337ba6df8b657b49afe629 87 Pfam PF06961 Protein of unknown function (DUF1294) 14 67 1.0E-20 T 23-04-2016 IPR010718 Protein of unknown function DUF1294 SPYM18_RS05965 05b50579ba337ba6df8b657b49afe629 87 PANTHER PTHR12962:SF1 1 86 7.1E-12 T 23-04-2016 SPYM18_RS05965 05b50579ba337ba6df8b657b49afe629 87 PANTHER PTHR12962 1 86 7.1E-12 T 23-04-2016 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 SUPERFAMILY SSF51569 1 277 1.06E-88 T 23-04-2016 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 Gene3D G3DSA:3.20.20.70 2 278 3.2E-112 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 PANTHER PTHR18866:SF100 1 441 4.2E-185 T 23-04-2016 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 Pfam PF02436 Conserved carboxylase domain 296 446 1.2E-50 T 23-04-2016 IPR003379 Carboxylase, conserved domain SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 SUPERFAMILY SSF89000 299 453 8.63E-50 T 23-04-2016 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 PANTHER PTHR18866 1 441 4.2E-185 T 23-04-2016 SPYM18_RS04945 bf55587d3941fa97f9a168cfa085eb9d 464 Pfam PF00682 HMGL-like 3 269 2.7E-49 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 Gene3D G3DSA:3.40.50.150 24 245 1.6E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 Pfam PF01555 DNA methylase 27 242 5.2E-20 T 23-04-2016 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 SUPERFAMILY SSF53335 11 41 3.87E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 SUPERFAMILY SSF53335 69 243 3.87E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PANTHER PTHR13370 173 252 1.1E-13 T 23-04-2016 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 203 221 4.7E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 184 201 4.7E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 226 246 4.7E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 25 39 4.7E-16 T 23-04-2016 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 SPYM18_RS03185 91d77a80e863ab2a7d3958350f2f7a89 254 PANTHER PTHR13370:SF7 173 252 1.1E-13 T 23-04-2016 SPYM18_RS06735 017bd9bafc73dfc7bab812c490c0449f 142 Pfam PF13673 Acetyltransferase (GNAT) domain 10 108 2.9E-11 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS06735 017bd9bafc73dfc7bab812c490c0449f 142 SUPERFAMILY SSF55729 5 112 1.03E-17 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS06735 017bd9bafc73dfc7bab812c490c0449f 142 Gene3D G3DSA:3.40.630.30 5 112 2.3E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS06735 017bd9bafc73dfc7bab812c490c0449f 142 PANTHER PTHR13355:SF8 3 131 1.2E-14 T 23-04-2016 SPYM18_RS06735 017bd9bafc73dfc7bab812c490c0449f 142 PANTHER PTHR13355 3 131 1.2E-14 T 23-04-2016 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 Gene3D G3DSA:3.40.50.450 1 214 1.4E-75 T 23-04-2016 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 336 46.823 T 23-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PANTHER PTHR13697:SF4 1 299 1.4E-125 T 23-04-2016 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PANTHER PTHR13697 1 299 1.4E-125 T 23-04-2016 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PIRSF PIRSF000532 1 322 5.6E-116 T 23-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 263 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 1.8E-84 T 23-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 Pfam PF00365 Phosphofructokinase 3 277 2.1E-105 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 4.8E-122 T 23-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 SUPERFAMILY SSF53784 1 301 1.96E-107 T 23-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS05325 8e58f260bf81380ebc5bf451c8c19237 337 ProSitePatterns PS00433 Phosphofructokinase signature. 245 263 - T 23-04-2016 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Gene3D G3DSA:3.30.1370.10 235 313 5.9E-8 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 SMART SM00322 223 290 4.0E-8 T 23-04-2016 IPR004087 K Homology domain GO:0003676 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Pfam PF00013 KH domain 229 283 1.2E-6 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 SMART SM00471 347 453 9.2E-12 T 23-04-2016 IPR003607 HD/PDEase domain SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Hamap MF_00335 Ribonuclease Y [rny]. 2 535 24.714 T 23-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Pfam PF12072 Domain of unknown function (DUF3552) 3 220 5.3E-40 T 23-04-2016 IPR022711 Ribonuclease Y, N-terminal SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 TIGRFAM TIGR00277 HDIG: HDIG domain 348 424 1.7E-23 T 23-04-2016 IPR006675 HDIG domain SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 5 535 4.6E-231 T 23-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Gene3D G3DSA:1.10.3210.10 331 511 6.7E-42 T 23-04-2016 IPR006674 HD domain SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 PANTHER PTHR12826 205 534 4.4E-138 T 23-04-2016 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 SUPERFAMILY SSF109604 336 485 8.98E-27 T 23-04-2016 SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 Pfam PF01966 HD domain 352 442 2.8E-17 T 23-04-2016 IPR006674 HD domain SPYM18_RS07095 62e375ce8d809e06b6dc8ac57bf29093 535 SUPERFAMILY SSF54791 223 319 8.07E-17 T 23-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 5 209 2.6E-71 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 Gene3D G3DSA:3.40.470.10 3 215 2.1E-85 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 PANTHER PTHR11264 1 215 4.5E-107 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 Pfam PF03167 Uracil DNA glycosylase superfamily 52 204 4.3E-22 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 55 64 - T 23-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 SUPERFAMILY SSF52141 3 215 7.85E-82 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 216 37.973 T 23-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 SMART SM00987 47 205 7.2E-33 T 23-04-2016 SPYM18_RS04155 03ed1c4033b40642ae61588d8b644302 217 SMART SM00986 47 205 7.2E-33 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 PANTHER PTHR18964 1 289 2.3E-67 T 23-04-2016 SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 Gene3D G3DSA:3.30.420.40 108 293 4.8E-55 T 23-04-2016 SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 Gene3D G3DSA:3.30.420.40 1 107 9.5E-24 T 23-04-2016 SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 SUPERFAMILY SSF53067 1 292 2.35E-60 T 23-04-2016 SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 Pfam PF00480 ROK family 4 291 1.4E-53 T 23-04-2016 IPR000600 ROK family SPYM18_RS01190 4dfd535d8273a61ff8d3c9de86d48056 312 PANTHER PTHR18964:SF109 1 289 2.3E-67 T 23-04-2016 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 SUPERFAMILY SSF103473 1 368 3.31E-63 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 Pfam PF07690 Major Facilitator Superfamily 2 273 2.6E-41 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 PANTHER PTHR23504 1 360 9.4E-70 T 23-04-2016 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 PRINTS PR01035 Tetracycline resistance protein signature 22 41 2.0E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 PRINTS PR01035 Tetracycline resistance protein signature 110 132 2.0E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 PRINTS PR01035 Tetracycline resistance protein signature 80 101 2.0E-7 T 23-04-2016 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 Gene3D G3DSA:1.20.1250.20 184 365 1.3E-28 T 23-04-2016 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 Gene3D G3DSA:1.20.1250.20 1 162 9.8E-32 T 23-04-2016 SPYM18_RS02415 579ab44465c9cd53f784d7392dca3b6a 373 PANTHER PTHR23504:SF14 1 360 9.4E-70 T 23-04-2016 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 Gene3D G3DSA:1.10.10.60 148 201 1.4E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 Gene3D G3DSA:3.40.50.2300 1 128 8.4E-24 T 23-04-2016 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 Pfam PF00072 Response regulator receiver domain 5 112 2.5E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 SMART SM00448 2 114 4.8E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 PANTHER PTHR26402 2 120 3.1E-22 T 23-04-2016 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 PANTHER PTHR26402:SF474 2 120 3.1E-22 T 23-04-2016 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 SUPERFAMILY SSF52172 1 130 3.98E-25 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 Gene3D G3DSA:1.10.10.60 202 247 1.3E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 SUPERFAMILY SSF46689 151 198 2.75E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 SMART SM00342 164 248 2.3E-15 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 Pfam PF12833 Helix-turn-helix domain 170 248 8.4E-15 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS04490 0d1b092c2d7c378549f484df5191e57d 262 SUPERFAMILY SSF46689 200 252 3.23E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Pfam PF00571 CBS domain 222 271 0.002 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Pfam PF00571 CBS domain 286 337 1.6E-6 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Pfam PF03471 Transporter associated domain 353 433 3.9E-15 T 23-04-2016 IPR005170 Transporter-associated domain SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 PANTHER PTHR22777:SF8 2 444 2.1E-177 T 23-04-2016 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 SUPERFAMILY SSF56176 353 433 2.54E-17 T 23-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Gene3D G3DSA:3.30.465.10 351 433 1.0E-23 T 23-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 SUPERFAMILY SSF54631 211 356 2.78E-28 T 23-04-2016 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Gene3D G3DSA:3.10.580.10 203 348 9.2E-15 T 23-04-2016 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 Pfam PF01595 Domain of unknown function DUF21 14 200 1.4E-46 T 23-04-2016 IPR002550 Domain of unknown function DUF21 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 PANTHER PTHR22777 2 444 2.1E-177 T 23-04-2016 SPYM18_RS01955 6647182ff2a1714cf5238e4ed0380f4a 444 SMART SM01091 352 436 2.3E-14 T 23-04-2016 IPR005170 Transporter-associated domain SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 SUPERFAMILY SSF48179 182 334 8.33E-53 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 Gene3D G3DSA:1.10.1040.10 187 329 1.3E-54 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 35.805 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 2.6E-50 T 23-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 Gene3D G3DSA:3.40.50.720 1 186 1.5E-60 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PIRSF PIRSF000114 1 335 6.3E-102 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 SUPERFAMILY SSF51735 5 182 1.4E-55 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PANTHER PTHR11728 1 338 2.4E-134 T 23-04-2016 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 163 1.3E-51 T 23-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS01070 3a6d839a0fcdd5efaa27cf5c4c2d2cfd 338 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 2.9E-43 T 23-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 PANTHER PTHR18964 8 146 1.2E-20 T 23-04-2016 SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 Gene3D G3DSA:1.10.10.10 8 130 2.8E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 PANTHER PTHR18964:SF125 8 146 1.2E-20 T 23-04-2016 SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 SMART SM00347 29 131 1.7E-14 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 SUPERFAMILY SSF46785 7 119 3.81E-21 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00600 8eccd7e4ee21094ea9950438e040dc80 147 Pfam PF01047 MarR family 36 92 6.4E-11 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS01120 2df49f22f7afd694aa8cd22b31ee9af7 448 SUPERFAMILY SSF55874 308 442 7.94E-10 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS01120 2df49f22f7afd694aa8cd22b31ee9af7 448 PANTHER PTHR40448 4 445 1.9E-48 T 23-04-2016 SPYM18_RS01120 2df49f22f7afd694aa8cd22b31ee9af7 448 PANTHER PTHR40448:SF1 4 445 1.9E-48 T 23-04-2016 SPYM18_RS01120 2df49f22f7afd694aa8cd22b31ee9af7 448 Pfam PF14501 GHKL domain 341 441 6.9E-13 T 23-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPYM18_RS01120 2df49f22f7afd694aa8cd22b31ee9af7 448 Gene3D G3DSA:3.30.565.10 314 420 1.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 Gene3D G3DSA:3.40.50.450 105 223 3.5E-8 T 23-04-2016 SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 277 1.1E-71 T 23-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 PANTHER PTHR32039 72 278 6.7E-86 T 23-04-2016 SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 PANTHER PTHR32039:SF8 72 278 6.7E-86 T 23-04-2016 SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 Pfam PF02481 DNA recombination-mediator protein A 68 269 3.3E-73 T 23-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 SPYM18_RS04855 aad2edba51d78d964d6d0f8d3eda451b 278 SUPERFAMILY SSF102405 74 274 3.66E-34 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 Gene3D G3DSA:3.40.190.10 117 225 3.2E-22 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 SMART SM00062 39 266 3.0E-45 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 SUPERFAMILY SSF53850 37 268 1.51E-48 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 43 264 8.2E-48 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 Gene3D G3DSA:3.40.190.10 226 268 5.6E-26 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 Gene3D G3DSA:3.40.190.10 38 116 5.6E-26 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 PANTHER PTHR18966:SF208 37 267 2.5E-25 T 23-04-2016 SPYM18_RS01445 4d2fbf62f2b1d46b1c11b27140137405 280 PANTHER PTHR18966 37 267 2.5E-25 T 23-04-2016 SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 SUPERFAMILY SSF52972 129 320 2.88E-63 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 Pfam PF01725 Ham1 family 130 318 2.5E-51 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 Gene3D G3DSA:3.90.950.10 127 322 1.4E-74 T 23-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 PANTHER PTHR11067:SF9 123 328 5.0E-70 T 23-04-2016 SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 128 322 48.072 T 23-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 PANTHER PTHR11067 123 328 5.0E-70 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 SPYM18_RS01880 b662fea0ca210270ef1af55f8763c3d2 328 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 129 320 2.7E-54 T 23-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 SPYM18_RS01495 66d18e3454bbea71913da805cef87cdd 298 PANTHER PTHR10120:SF19 16 298 3.8E-90 T 23-04-2016 SPYM18_RS01495 66d18e3454bbea71913da805cef87cdd 298 Gene3D G3DSA:3.30.2010.10 69 159 3.2E-32 T 23-04-2016 SPYM18_RS01495 66d18e3454bbea71913da805cef87cdd 298 PANTHER PTHR10120 16 298 3.8E-90 T 23-04-2016 SPYM18_RS01495 66d18e3454bbea71913da805cef87cdd 298 Pfam PF01435 Peptidase family M48 84 298 1.5E-35 T 23-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 SPYM18_RS01495 66d18e3454bbea71913da805cef87cdd 298 Hamap MF_00188 Protease HtpX [htpX]. 10 298 27.001 T 23-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 374 390 9.2E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 359 374 9.2E-5 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 Pfam PF12833 Helix-turn-helix domain 314 392 9.1E-21 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 SMART SM00342 308 390 2.4E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 SUPERFAMILY SSF46689 292 341 2.96E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 TIGRFAM TIGR04094 adjacent_YSIRK: YSIRK-targeted surface antigen transcriptional regulator 6 390 2.4E-166 T 23-04-2016 IPR024022 Transcription regulator HTH, surface antigen SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 Gene3D G3DSA:1.10.10.60 286 342 4.0E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 SUPERFAMILY SSF46689 350 392 1.3E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 PANTHER PTHR11019 224 392 3.9E-23 T 23-04-2016 SPYM18_RS08815 1fc53dcb605ef679e0547af8e85c0e6f 394 Gene3D G3DSA:1.10.10.60 344 393 1.3E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01170 f1ec90fe0ffeef74e52118b2c3fc8e3d 276 PANTHER PTHR32243 1 276 2.6E-87 T 23-04-2016 SPYM18_RS01170 f1ec90fe0ffeef74e52118b2c3fc8e3d 276 SUPERFAMILY SSF161098 10 276 1.12E-67 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01170 f1ec90fe0ffeef74e52118b2c3fc8e3d 276 Gene3D G3DSA:1.10.3720.10 5 263 2.6E-62 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01170 f1ec90fe0ffeef74e52118b2c3fc8e3d 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 262 2.8E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 SUPERFAMILY SSF50621 237 366 6.28E-48 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 295 312 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 258 273 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 349 362 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 67 85 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 161 172 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 127 139 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 275 290 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 32 48 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PRINTS PR00992 Alanine racemase signature 201 228 5.3E-66 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PANTHER PTHR30511 3 366 5.7E-141 T 23-04-2016 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 Pfam PF01168 Alanine racemase, N-terminal domain 13 228 4.7E-65 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 SUPERFAMILY SSF51419 13 242 3.79E-62 T 23-04-2016 IPR029066 PLP-binding barrel SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 Gene3D G3DSA:3.20.20.10 15 221 1.7E-69 T 23-04-2016 IPR029066 PLP-binding barrel SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 PANTHER PTHR30511:SF0 3 366 5.7E-141 T 23-04-2016 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 SMART SM01005 242 366 8.7E-60 T 23-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 TIGRFAM TIGR00492 alr: alanine racemase 8 366 1.0E-108 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 Pfam PF00842 Alanine racemase, C-terminal domain 242 366 8.4E-38 T 23-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 Hamap MF_01201 Alanine racemase. 6 366 33.691 T 23-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 23-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS08075 7b38f224fa79dc1cd28a07e3c4592ab2 366 Gene3D G3DSA:2.40.37.10 222 366 1.3E-53 T 23-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 11 715 0.0 T 23-04-2016 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 KEGG: 00900+3.4.22.- SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Gene3D G3DSA:1.20.1560.10 157 461 3.8E-74 T 23-04-2016 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 ProSitePatterns PS00211 ABC transporters family signature. 621 635 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Gene3D G3DSA:3.90.70.10 13 141 1.4E-16 T 23-04-2016 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Pfam PF00664 ABC transporter transmembrane region 168 438 4.0E-60 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 SMART SM00382 509 694 2.7E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Pfam PF00005 ABC transporter 500 649 3.0E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Gene3D G3DSA:3.40.50.300 484 711 3.1E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 SUPERFAMILY SSF52540 478 715 1.57E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 PANTHER PTHR24221 138 714 7.2E-159 T 23-04-2016 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 PANTHER PTHR24221 68 118 7.2E-159 T 23-04-2016 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 Pfam PF03412 Peptidase C39 family 7 142 1.4E-42 T 23-04-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 SPYM18_RS02345 b2ee4fe04b98a05772b32afec9f3af91 717 SUPERFAMILY SSF90123 150 461 5.62E-65 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS03180 b0f37cef15acbcc88db6a6a7bbe7edcc 160 SUPERFAMILY SSF53335 3 152 3.84E-15 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03180 b0f37cef15acbcc88db6a6a7bbe7edcc 160 Pfam PF08241 Methyltransferase domain 19 116 1.3E-5 T 23-04-2016 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 SPYM18_RS03180 b0f37cef15acbcc88db6a6a7bbe7edcc 160 Gene3D G3DSA:3.40.50.150 4 140 2.8E-11 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 PIRSF PIRSF000429 1 364 4.5E-71 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Pfam PF00108 Thiolase, N-terminal domain 4 238 4.3E-27 T 23-04-2016 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Gene3D G3DSA:3.40.47.10 137 182 6.3E-32 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Gene3D G3DSA:3.40.47.10 248 362 6.3E-32 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 SUPERFAMILY SSF53901 247 362 7.13E-24 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 362 1.9E-96 T 23-04-2016 IPR002155 Thiolase GO:0008152|GO:0016747 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Pfam PF02803 Thiolase, C-terminal domain 246 362 4.2E-22 T 23-04-2016 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 PANTHER PTHR18919 1 365 2.3E-62 T 23-04-2016 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 PANTHER PTHR18919:SF69 1 365 2.3E-62 T 23-04-2016 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Gene3D G3DSA:3.40.47.10 3 118 2.0E-26 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 Gene3D G3DSA:3.40.47.10 183 244 2.0E-26 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS02555 4537e3efedc57a2d957bcad340eeba7d 382 SUPERFAMILY SSF53901 3 241 1.14E-36 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Gene3D G3DSA:2.40.50.140 1 65 1.0E-21 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.216 T 23-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 SUPERFAMILY SSF50249 1 62 1.43E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 SUPERFAMILY SSF46929 150 196 1.2E-9 T 23-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Pfam PF14520 Helix-hairpin-helix domain 71 127 9.7E-12 T 23-04-2016 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Gene3D G3DSA:1.10.150.20 66 141 4.4E-27 T 23-04-2016 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 PANTHER PTHR33796 2 198 6.2E-66 T 23-04-2016 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 SUPERFAMILY SSF47781 65 134 4.17E-20 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Pfam PF01330 RuvA N terminal domain 1 61 1.8E-18 T 23-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Gene3D G3DSA:1.10.8.10 150 196 5.0E-13 T 23-04-2016 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 Pfam PF07499 RuvA, C-terminal domain 152 196 6.7E-11 T 23-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 SMART SM00278 107 126 8.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 SMART SM00278 72 91 2.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS09315 238050520655ed31afa18f3286c0c145 198 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 2 196 3.0E-49 T 23-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 SMART SM00382 49 233 1.6E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 Gene3D G3DSA:3.40.50.300 3 255 5.9E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 Pfam PF00005 ABC transporter 41 184 1.6E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220 37 263 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220 290 322 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220 5 15 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220:SF333 37 263 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220:SF333 290 322 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 PANTHER PTHR24220:SF333 5 15 6.6E-91 T 23-04-2016 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS02505 2749c08aa0e21a5341ec2c9fed1e48f8 330 SUPERFAMILY SSF52540 37 251 3.16E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 23-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 SUPERFAMILY SSF55120 46 236 1.76E-44 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 SUPERFAMILY SSF55174 1 58 4.12E-10 T 23-04-2016 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 Pfam PF01479 S4 domain 1 38 4.4E-6 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 PANTHER PTHR21600:SF19 1 235 3.4E-62 T 23-04-2016 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 SMART SM00363 1 66 3.3E-7 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 2.5E-48 T 23-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 Pfam PF00849 RNA pseudouridylate synthase 62 197 1.7E-24 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 Gene3D G3DSA:3.10.290.10 1 57 4.7E-15 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS05855 190ca3061f7ddbc975d00416c801da1d 243 PANTHER PTHR21600 1 235 3.4E-62 T 23-04-2016 SPYM18_RS00870 520fa829e569796f92ecc6ed861e9a7e 208 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 5 206 8.1E-48 T 23-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 SPYM18_RS00870 520fa829e569796f92ecc6ed861e9a7e 208 Pfam PF01813 ATP synthase subunit D 12 206 1.9E-51 T 23-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 SPYM18_RS00870 520fa829e569796f92ecc6ed861e9a7e 208 PANTHER PTHR11671 1 206 2.4E-70 T 23-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 SPYM18_RS00870 520fa829e569796f92ecc6ed861e9a7e 208 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 3 208 19.625 T 23-04-2016 IPR002699 ATPase, V1 complex, subunit D GO:0042626 SPYM18_RS00870 520fa829e569796f92ecc6ed861e9a7e 208 PANTHER PTHR11671:SF2 1 206 2.4E-70 T 23-04-2016 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 SUPERFAMILY SSF52540 283 482 4.61E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 Gene3D G3DSA:3.40.50.300 291 482 5.3E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 SUPERFAMILY SSF52540 21 249 1.52E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 PANTHER PTHR24220 23 406 3.2E-59 T 23-04-2016 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 SMART SM00382 48 238 2.4E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 SMART SM00382 312 483 1.5E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 Gene3D G3DSA:3.40.50.300 19 253 1.0E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 Pfam PF00005 ABC transporter 308 437 1.3E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 Pfam PF00005 ABC transporter 44 190 4.7E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08020 159386ea4d20a6e6261b39648883380b 484 PANTHER PTHR24220:SF193 23 406 3.2E-59 T 23-04-2016 SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 1.1E-19 T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 148 9.8E-27 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 SUPERFAMILY SSF55653 57 149 4.19E-25 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 23.45 T 23-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 Gene3D G3DSA:3.40.5.10 1 52 8.1E-21 T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 PANTHER PTHR21368 1 147 3.0E-40 T 23-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 23-04-2016 IPR020070 Ribosomal protein L9, N-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 SUPERFAMILY SSF55658 1 56 2.96E-15 T 23-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 Gene3D G3DSA:3.10.430.100 61 149 2.1E-27 T 23-04-2016 IPR020069 Ribosomal protein L9, C-terminal SPYM18_RS09485 7e2aa9cad25731255ad47038d6faaf50 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.0E-38 T 23-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 4.8E-37 T 23-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 PANTHER PTHR20941 1 119 1.9E-33 T 23-04-2016 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 Pfam PF02152 Dihydroneopterin aldolase 4 116 1.3E-30 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 SMART SM00905 4 117 2.2E-48 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 Gene3D G3DSA:3.30.1130.10 1 119 2.9E-41 T 23-04-2016 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 2.8E-28 T 23-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 SPYM18_RS04570 083855b3f32449a9bb747f514b20f2f1 119 SUPERFAMILY SSF55620 2 119 9.45E-39 T 23-04-2016 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Pfam PF00082 Subtilase family 121 573 1.6E-47 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 126 137 - T 23-04-2016 IPR023827 Peptidase S8, subtilisin, Asp-active site SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Pfam PF13585 C-terminal domain of CHU protein family 819 917 8.3E-7 T 23-04-2016 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 193 203 - T 23-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Gene3D G3DSA:3.50.30.30 344 480 2.1E-26 T 23-04-2016 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 PRINTS PR00723 Subtilisin serine protease family (S8) signature 509 525 5.3E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 PRINTS PR00723 Subtilisin serine protease family (S8) signature 121 140 5.3E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 PRINTS PR00723 Subtilisin serine protease family (S8) signature 189 202 5.3E-14 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 PANTHER PTHR10795 110 580 2.6E-63 T 23-04-2016 IPR015500 Peptidase S8, subtilisin-related SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Gene3D G3DSA:3.40.50.200 110 343 3.0E-68 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Gene3D G3DSA:3.40.50.200 481 580 3.0E-68 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 SUPERFAMILY SSF52743 111 345 8.38E-57 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 SUPERFAMILY SSF52743 469 580 8.38E-57 T 23-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Pfam PF06280 Fn3-like domain 597 707 6.2E-28 T 23-04-2016 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 PANTHER PTHR10795:SF419 110 580 2.6E-63 T 23-04-2016 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 510 520 - T 23-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 SUPERFAMILY SSF52025 328 453 3.4E-18 T 23-04-2016 SPYM18_RS08935 e95fd569a4669b782bfb8494f3bc065b 1150 Pfam PF02225 PA domain 370 445 1.4E-15 T 23-04-2016 IPR003137 PA domain SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 PANTHER PTHR22769:SF37 13 150 1.2E-23 T 23-04-2016 SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 Gene3D G3DSA:3.90.79.10 10 151 6.3E-30 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 Pfam PF00293 NUDIX domain 23 145 8.6E-19 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 PRINTS PR00502 NUDIX hydrolase family signature 59 74 1.9E-5 T 23-04-2016 IPR020476 NUDIX hydrolase SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 PRINTS PR00502 NUDIX hydrolase family signature 45 59 1.9E-5 T 23-04-2016 IPR020476 NUDIX hydrolase SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 SUPERFAMILY SSF55811 7 152 3.79E-29 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 PANTHER PTHR22769 13 150 1.2E-23 T 23-04-2016 SPYM18_RS02270 79397bc705f39c17f5b5a18a3f05a70d 158 ProSitePatterns PS00893 Nudix box signature. 50 71 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPYM18_RS01300 7d2196d4afa1befe75b34106850e3c91 389 PANTHER PTHR22926:SF3 5 371 8.9E-91 T 23-04-2016 SPYM18_RS01300 7d2196d4afa1befe75b34106850e3c91 389 Pfam PF00953 Glycosyl transferase family 4 90 247 1.8E-39 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS01300 7d2196d4afa1befe75b34106850e3c91 389 ProSitePatterns PS01348 MraY family signature 2. 165 176 - T 23-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS01300 7d2196d4afa1befe75b34106850e3c91 389 PANTHER PTHR22926 5 371 8.9E-91 T 23-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS07970 3f6cfef3348bc8a08cca6ddfa3e1335f 82 SUPERFAMILY SSF51621 16 72 1.36E-16 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS07970 3f6cfef3348bc8a08cca6ddfa3e1335f 82 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 7 70 1.3E-13 T 23-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SPYM18_RS07970 3f6cfef3348bc8a08cca6ddfa3e1335f 82 PANTHER PTHR22931 15 79 2.6E-26 T 23-04-2016 SPYM18_RS07970 3f6cfef3348bc8a08cca6ddfa3e1335f 82 Gene3D G3DSA:3.20.20.60 16 72 2.7E-19 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS07970 3f6cfef3348bc8a08cca6ddfa3e1335f 82 PANTHER PTHR22931:SF9 15 79 2.6E-26 T 23-04-2016 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 139 1.2E-31 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 Pfam PF02502 Ribose/Galactose Isomerase 3 137 4.0E-37 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 Hamap MF_01555 Galactose-6-phosphate isomerase subunit LacA [lacA]. 1 141 39.44 T 23-04-2016 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 SUPERFAMILY SSF89623 1 140 2.88E-43 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 TIGRFAM TIGR01118 lacA: galactose-6-phosphate isomerase, LacA subunit 1 140 1.6E-73 T 23-04-2016 IPR004783 Galactose-6-phosphate isomerase subunit LacA GO:0005990|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 PANTHER PTHR30345 1 140 6.2E-85 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 PIRSF PIRSF005384 1 141 5.9E-38 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 PANTHER PTHR30345:SF5 1 140 6.2E-85 T 23-04-2016 SPYM18_RS07375 47f195fe95abf24e0aa3d1bd535af7f5 141 Gene3D G3DSA:3.40.1400.10 1 140 2.3E-39 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 PANTHER PTHR24221 14 587 8.4E-84 T 23-04-2016 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 Gene3D G3DSA:1.20.1560.10 18 326 4.9E-34 T 23-04-2016 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 Pfam PF00005 ABC transporter 360 508 5.2E-23 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 SMART SM00382 369 570 7.7E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 PANTHER PTHR24221:SF138 14 587 8.4E-84 T 23-04-2016 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 SUPERFAMILY SSF90123 14 329 3.79E-38 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 Gene3D G3DSA:3.40.50.300 344 571 1.6E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 Pfam PF00664 ABC transporter transmembrane region 34 300 2.5E-19 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS08040 98593f0149282e4229ee910e86589efc 587 SUPERFAMILY SSF52540 340 578 1.38E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 Pfam PF00005 ABC transporter 26 178 2.0E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 Pfam PF09383 NIL domain 278 347 1.0E-16 T 23-04-2016 IPR018449 NIL domain SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 SMART SM00382 34 230 2.6E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 SUPERFAMILY SSF52540 5 249 6.81E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 Gene3D G3DSA:3.30.70.260 265 352 2.8E-24 T 23-04-2016 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 PANTHER PTHR24220 7 271 5.8E-138 T 23-04-2016 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 SUPERFAMILY SSF55021 267 351 3.55E-18 T 23-04-2016 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 PANTHER PTHR24220:SF549 7 271 5.8E-138 T 23-04-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 SMART SM00930 275 350 6.2E-23 T 23-04-2016 IPR018449 NIL domain SPYM18_RS01455 bf99678f1f8bb8ad10f66ea5c1bba64b 354 Gene3D G3DSA:3.40.50.300 4 250 3.1E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00750 3cdff3ed9e839af10c9e5a4c5c12e678 524 Pfam PF05738 Cna protein B-type domain 72 126 6.7E-6 T 23-04-2016 IPR008454 Collagen-binding surface protein Cna-like, B-type domain SPYM18_RS00750 3cdff3ed9e839af10c9e5a4c5c12e678 524 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 251 291 1.8E-13 T 23-04-2016 IPR023849 Uncharacterised domain CHP03934, TQXA SPYM18_RS00750 3cdff3ed9e839af10c9e5a4c5c12e678 524 Pfam PF08341 Thioester domain 157 356 4.8E-53 T 23-04-2016 IPR013552 Thioester domain SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 PANTHER PTHR13779 1 327 1.8E-171 T 23-04-2016 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 2.1E-139 T 23-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 332 162.834 T 23-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 SUPERFAMILY SSF46785 257 328 7.16E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 234 8.2E-113 T 23-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 SMART SM00382 51 184 1.3E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 330 2.0E-41 T 23-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Gene3D G3DSA:3.40.50.300 20 175 6.9E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 PANTHER PTHR13779:SF25 1 327 1.8E-171 T 23-04-2016 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Gene3D G3DSA:1.10.10.10 257 328 5.3E-32 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 SUPERFAMILY SSF52540 20 251 6.74E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Gene3D G3DSA:1.10.8.60 183 255 1.3E-31 T 23-04-2016 SPYM18_RS00330 a7ff8390b2a450be9cbd0281f0a052f8 332 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 1.2E-30 T 23-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 SUPERFAMILY SSF52096 7 255 9.22E-83 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 Gene3D G3DSA:3.90.226.10 9 214 9.4E-50 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PANTHER PTHR22855 1 256 1.3E-89 T 23-04-2016 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 100 113 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 129 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 144 153 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 60 78 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 81 97 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 35 46 1.6E-42 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 256 35.475 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 9 95 6.6E-40 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 PANTHER PTHR22855:SF42 1 256 1.3E-89 T 23-04-2016 SPYM18_RS07845 b9a7683c5b011dbd9b72b43083a00ce1 256 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 7 256 8.6E-105 T 23-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 Pfam PF00482 Type II secretion system (T2SS), protein F 12 131 1.9E-9 T 23-04-2016 IPR018076 Type II secretion system F domain SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 Pfam PF00482 Type II secretion system (T2SS), protein F 199 319 8.8E-17 T 23-04-2016 IPR018076 Type II secretion system F domain SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 PRINTS PR00812 Bacterial general secretion pathway protein F signature 308 327 2.1E-5 T 23-04-2016 IPR003004 GspF/PilC family SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 PRINTS PR00812 Bacterial general secretion pathway protein F signature 103 131 2.1E-5 T 23-04-2016 IPR003004 GspF/PilC family SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 PRINTS PR00812 Bacterial general secretion pathway protein F signature 292 306 2.1E-5 T 23-04-2016 IPR003004 GspF/PilC family SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 PANTHER PTHR30012 2 328 1.1E-49 T 23-04-2016 SPYM18_RS00650 f9b0ff459850b68eb7908849444e7cb2 328 PANTHER PTHR30012:SF0 2 328 1.1E-49 T 23-04-2016 SPYM18_RS02275 0cc4d991d71c1a7a98cdf74a4a69d679 148 PANTHER PTHR24221 2 103 6.7E-31 T 23-04-2016 SPYM18_RS02275 0cc4d991d71c1a7a98cdf74a4a69d679 148 Pfam PF00005 ABC transporter 12 106 3.6E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS02275 0cc4d991d71c1a7a98cdf74a4a69d679 148 Gene3D G3DSA:3.40.50.300 3 110 9.8E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02275 0cc4d991d71c1a7a98cdf74a4a69d679 148 SUPERFAMILY SSF52540 4 104 1.91E-26 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 SUPERFAMILY SSF53633 11 264 2.36E-62 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 Pfam PF00696 Amino acid kinase family 11 238 1.1E-34 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 Gene3D G3DSA:3.40.1160.10 11 264 5.0E-53 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 TIGRFAM TIGR01027 proB: glutamate 5-kinase 11 266 6.2E-81 T 23-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PRINTS PR00474 Glutamate 5-kinase family signature 157 184 3.3E-48 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PRINTS PR00474 Glutamate 5-kinase family signature 47 61 3.3E-48 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PRINTS PR00474 Glutamate 5-kinase family signature 218 238 3.3E-48 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 3.3E-48 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PRINTS PR00474 Glutamate 5-kinase family signature 81 109 3.3E-48 T 23-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PANTHER PTHR11063:SF12 1 264 6.3E-70 T 23-04-2016 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PIRSF PIRSF000729 5 272 2.7E-83 T 23-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 PANTHER PTHR11063 1 264 6.3E-70 T 23-04-2016 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 Hamap MF_00456 Glutamate 5-kinase [proB]. 10 267 34.349 T 23-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07240 fcbdcb75c157c5bde3181732860db826 273 ProSitePatterns PS00902 Glutamate 5-kinase signature. 216 233 - T 23-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Gene3D G3DSA:3.40.1440.10 16 91 4.4E-9 T 23-04-2016 IPR027299 GIY-YIG domain SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 SUPERFAMILY SSF47781 502 593 6.04E-18 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Gene3D G3DSA:1.10.150.20 537 586 2.4E-16 T 23-04-2016 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 26.896 T 23-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Gene3D G3DSA:4.10.860.10 181 235 1.0E-14 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Pfam PF01541 GIY-YIG catalytic domain 17 90 1.1E-9 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Pfam PF02151 UvrB/uvrC motif 196 228 5.4E-9 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 SUPERFAMILY SSF82771 15 97 6.93E-22 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 376 523 3.7E-47 T 23-04-2016 IPR001162 UvrC family homology region SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 PANTHER PTHR30562 2 588 3.9E-249 T 23-04-2016 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 SMART SM00465 15 95 5.3E-19 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 PANTHER PTHR30562:SF1 2 588 3.9E-249 T 23-04-2016 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 570 3.3E-184 T 23-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 SPYM18_RS04505 60fd363364d6ab1f215b13c30f07743c 598 SUPERFAMILY SSF46600 183 235 1.15E-12 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 SUPERFAMILY SSF102114 45 119 7.46E-8 T 23-04-2016 SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 Gene3D G3DSA:3.80.30.10 86 199 5.3E-16 T 23-04-2016 SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 24 173 8.3E-60 T 23-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 PANTHER PTHR30352 6 204 2.2E-100 T 23-04-2016 SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 PIRSF PIRSF000368 14 188 1.5E-72 T 23-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 Pfam PF13353 4Fe-4S single cluster domain 33 171 2.2E-52 T 23-04-2016 SPYM18_RS09255 309fd48b1c03bbb2bae8e634f44c91aa 204 PANTHER PTHR30352:SF2 6 204 2.2E-100 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 SMART SM00354 1 71 1.3E-33 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 Gene3D G3DSA:1.10.260.40 2 53 1.4E-23 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 PANTHER PTHR30146 1 323 5.3E-93 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 SUPERFAMILY SSF53822 61 323 1.21E-52 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 PANTHER PTHR30146:SF31 1 323 5.3E-93 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 Pfam PF13377 Periplasmic binding protein-like domain 163 321 1.5E-21 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 SUPERFAMILY SSF47413 1 58 2.95E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 Gene3D G3DSA:3.40.50.2300 54 167 6.1E-34 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 Gene3D G3DSA:3.40.50.2300 168 296 1.1E-27 T 23-04-2016 SPYM18_RS06690 63653824d8845aaeda255755bffd25ac 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 5.6E-18 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS05715 4d08c025feac1df3457051992ebfa95f 278 SUPERFAMILY SSF161098 4 278 1.78E-62 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05715 4d08c025feac1df3457051992ebfa95f 278 PANTHER PTHR32243:SF4 1 278 3.6E-86 T 23-04-2016 SPYM18_RS05715 4d08c025feac1df3457051992ebfa95f 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 270 7.6E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05715 4d08c025feac1df3457051992ebfa95f 278 PANTHER PTHR32243 1 278 3.6E-86 T 23-04-2016 SPYM18_RS05715 4d08c025feac1df3457051992ebfa95f 278 Gene3D G3DSA:1.10.3720.10 2 266 1.3E-60 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 PANTHER PTHR41284 2 71 1.6E-24 T 23-04-2016 SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 PANTHER PTHR41284:SF1 2 71 1.6E-24 T 23-04-2016 SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 PIRSF PIRSF037262 1 71 1.7E-30 T 23-04-2016 IPR010673 Protein of unknown function UPF0346 SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 Gene3D G3DSA:1.10.150.260 2 71 1.6E-29 T 23-04-2016 IPR023089 YozE SAM-like domain SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 Pfam PF06855 YozE SAM-like fold 4 69 1.9E-24 T 23-04-2016 IPR023089 YozE SAM-like domain SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 Hamap MF_01538 UPF0346 protein . 1 71 22.519 T 23-04-2016 IPR010673 Protein of unknown function UPF0346 SPYM18_RS02230 b85abdf7e761d8481a13ded4ed63ed21 71 SUPERFAMILY SSF140652 2 71 4.71E-28 T 23-04-2016 IPR023089 YozE SAM-like domain SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 23-04-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 PANTHER PTHR15238:SF3 1 49 2.8E-16 T 23-04-2016 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 Pfam PF00471 Ribosomal protein L33 3 49 9.7E-18 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.423 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.2E-16 T 23-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 SUPERFAMILY SSF57829 1 49 3.91E-15 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPYM18_RS09390 4c5fcdcbd977801f0b3d723f6838ed53 49 PANTHER PTHR15238 1 49 2.8E-16 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 356 47.435 T 23-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 Pfam PF00117 Glutamine amidotransferase class-I 175 350 1.0E-43 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 SMART SM01097 2 132 6.0E-89 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00097 Anthranilate synthase component II signature 327 340 2.1E-7 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.1E-7 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.1E-7 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 Gene3D G3DSA:3.40.50.880 156 354 2.2E-64 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 4.5E-12 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 4.5E-12 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 4.5E-12 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 353 4.6E-143 T 23-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 SUPERFAMILY SSF52317 140 354 7.37E-58 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PANTHER PTHR11405 2 356 1.9E-205 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 8.4E-53 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 Gene3D G3DSA:3.50.30.20 2 145 4.2E-61 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 SUPERFAMILY SSF52021 2 145 3.79E-57 T 23-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 5.0E-34 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 5.0E-34 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 5.0E-34 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 5.0E-34 T 23-04-2016 SPYM18_RS03845 20aa0f1892ae8317bdd68d50bc2cb436 360 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 5.0E-34 T 23-04-2016 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 SUPERFAMILY SSF55252 79 141 4.19E-18 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PANTHER PTHR34471:SF1 1 143 5.9E-42 T 23-04-2016 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 143 7.7E-56 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 83 137 7.0E-6 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 Hamap MF_00173 Arginine repressor [argR]. 1 145 54.809 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 Pfam PF02863 Arginine repressor, C-terminal domain 79 141 1.6E-20 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 Gene3D G3DSA:3.30.1360.40 79 141 6.8E-24 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PRINTS PR01467 Bacterial arginine repressor signature 84 97 2.1E-19 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PRINTS PR01467 Bacterial arginine repressor signature 21 34 2.1E-19 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PRINTS PR01467 Bacterial arginine repressor signature 37 52 2.1E-19 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PRINTS PR01467 Bacterial arginine repressor signature 114 129 2.1E-19 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 SUPERFAMILY SSF46785 1 68 1.81E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 Pfam PF01316 Arginine repressor, DNA binding domain 1 66 1.8E-23 T 23-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 PANTHER PTHR34471 1 143 5.9E-42 T 23-04-2016 SPYM18_RS09340 45b95d8b483ea3820016c88cb1be6d4f 145 Gene3D G3DSA:1.10.10.10 10 66 4.9E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Gene3D G3DSA:3.30.479.20 286 322 9.1E-27 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Gene3D G3DSA:3.30.479.20 153 189 9.1E-27 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 340 4.6E-92 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Hamap MF_00050 Elongation factor Ts [tsf]. 1 341 65.389 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Pfam PF00889 Elongation factor TS 71 323 1.0E-65 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Gene3D G3DSA:3.30.479.20 57 147 5.3E-16 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 SUPERFAMILY SSF54713 249 323 1.64E-34 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 SUPERFAMILY SSF54713 177 206 1.64E-34 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 SUPERFAMILY SSF54713 57 92 1.64E-34 T 23-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 SUPERFAMILY SSF46934 4 55 5.53E-18 T 23-04-2016 IPR009060 UBA-like GO:0005515 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 23-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Gene3D G3DSA:1.10.8.10 2 55 2.3E-25 T 23-04-2016 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 Gene3D G3DSA:1.10.286.20 249 277 6.0E-6 T 23-04-2016 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 23-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 PANTHER PTHR11741 1 209 8.3E-115 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 SPYM18_RS09215 9c85d48e60303d6c282b7526ddf99ee5 346 PANTHER PTHR11741 252 343 8.3E-115 T 23-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 PANTHER PTHR30146 2 310 1.5E-96 T 23-04-2016 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 Gene3D G3DSA:3.40.50.2300 55 169 1.2E-43 T 23-04-2016 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 SUPERFAMILY SSF53822 60 315 1.99E-64 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 SMART SM00354 2 72 7.0E-38 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 Gene3D G3DSA:3.40.50.2300 170 303 9.6E-29 T 23-04-2016 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 SUPERFAMILY SSF47413 3 60 1.52E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 2.0E-20 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 Pfam PF13377 Periplasmic binding protein-like domain 166 320 2.6E-23 T 23-04-2016 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 PANTHER PTHR30146:SF31 2 310 1.5E-96 T 23-04-2016 SPYM18_RS08120 46fae13417fdcd5b7624d29666741f91 321 Gene3D G3DSA:1.10.260.40 4 54 3.0E-25 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 530 545 5.0E-12 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 546 566 5.0E-12 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 535 570 1.1E-5 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 36 7.5E-14 T 23-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 PANTHER PTHR18937 156 517 1.2E-16 T 23-04-2016 SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 Pfam PF00746 Gram positive anchor 530 563 3.5E-9 T 23-04-2016 IPR019948 Gram-positive anchor SPYM18_RS08810 c9b24778021436f8bc04648c9ac86412 570 Pfam PF04650 YSIRK type signal peptide 5 30 4.1E-11 T 23-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 168 256 3.6E-16 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 SUPERFAMILY SSF52794 166 265 4.88E-35 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 Gene3D G3DSA:3.40.930.10 1 151 5.7E-48 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 Pfam PF02378 Phosphotransferase system, EIIC 296 592 8.3E-22 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 8.4E-40 T 23-04-2016 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 Gene3D G3DSA:3.40.50.2300 162 266 1.9E-42 T 23-04-2016 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 286 644 1.5E-114 T 23-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 SUPERFAMILY SSF55804 1 148 7.98E-40 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 PANTHER PTHR30505:SF0 43 382 7.6E-260 T 23-04-2016 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 PANTHER PTHR30505:SF0 402 641 7.6E-260 T 23-04-2016 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 PANTHER PTHR30505 43 382 7.6E-260 T 23-04-2016 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 PANTHER PTHR30505 402 641 7.6E-260 T 23-04-2016 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 167 249 1.6E-30 T 23-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 SPYM18_RS03940 f93d1d491f713ebd563599c64d97149c 648 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 3.7E-32 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 SUPERFAMILY SSF52540 1 427 3.72E-178 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Gene3D G3DSA:1.10.300.10 100 194 2.2E-38 T 23-04-2016 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 SMART SM00788 3 422 2.2E-301 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 23-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 9.3E-190 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Gene3D G3DSA:3.40.440.10 1 93 6.1E-73 T 23-04-2016 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Gene3D G3DSA:3.40.440.10 195 264 6.1E-73 T 23-04-2016 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 5.2E-183 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 PANTHER PTHR11846 4 426 2.8E-258 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Gene3D G3DSA:3.90.170.10 265 423 3.2E-71 T 23-04-2016 SPYM18_RS00885 5504df9c6192672bcf2bd1a7de502e42 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 215.28 T 23-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 Gene3D G3DSA:3.90.1170.10 23 135 6.2E-54 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 PANTHER PTHR12220 1 135 1.2E-70 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 SUPERFAMILY SSF54686 1 135 2.62E-55 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 3.7E-49 T 23-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 23-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.214 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 3.3E-57 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 23-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.6E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.6E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.6E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS00405 2c680d16a94471da7ff3fd1a502a90ed 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.6E-37 T 23-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 78 258 5.6E-50 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 117 129 1.9E-14 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 168 183 1.9E-14 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 91 106 1.9E-14 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 SUPERFAMILY SSF50891 77 263 4.97E-56 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PANTHER PTHR11071 210 265 2.0E-85 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PANTHER PTHR11071 8 187 2.0E-85 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PANTHER PTHR11071:SF282 210 265 2.0E-85 T 23-04-2016 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 PANTHER PTHR11071:SF282 8 187 2.0E-85 T 23-04-2016 SPYM18_RS02185 c87527d0046c11dbfe56a7af9047e261 268 Gene3D G3DSA:2.40.100.10 68 263 2.4E-64 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 PIRSF PIRSF019345 1 181 1.3E-49 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 Gene3D G3DSA:1.10.10.10 83 157 9.9E-34 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 SUPERFAMILY SSF46785 83 157 2.1E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 Gene3D G3DSA:1.10.10.10 5 78 2.0E-17 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 PANTHER PTHR34298:SF2 1 176 1.6E-50 T 23-04-2016 SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 PANTHER PTHR34298 1 176 1.6E-50 T 23-04-2016 SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 SUPERFAMILY SSF46785 3 78 3.4E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 164 6.5E-54 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 179 33.336 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPYM18_RS01905 cea51ce42053d454322dc9efb7519ac1 183 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 5 168 3.5E-44 T 23-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 Gene3D G3DSA:3.40.50.300 326 557 9.6E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 Gene3D G3DSA:1.20.1560.10 4 316 9.8E-50 T 23-04-2016 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 Pfam PF00664 ABC transporter transmembrane region 16 282 3.9E-34 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 SMART SM00382 353 539 3.8E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 SUPERFAMILY SSF52540 322 563 2.49E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 PANTHER PTHR24221 6 568 1.4E-169 T 23-04-2016 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 Pfam PF00005 ABC transporter 344 493 1.1E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 SUPERFAMILY SSF90123 5 311 1.12E-56 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS01080 59d15e5e45da2042fd38913d1b00401e 568 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 23-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 PANTHER PTHR21600 1 236 1.9E-54 T 23-04-2016 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 Gene3D G3DSA:3.10.290.10 1 63 2.0E-13 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 PANTHER PTHR21600:SF19 1 236 1.9E-54 T 23-04-2016 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 Pfam PF01479 S4 domain 1 46 8.1E-7 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 Pfam PF00849 RNA pseudouridylate synthase 62 194 1.7E-17 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 SUPERFAMILY SSF55174 1 57 3.92E-9 T 23-04-2016 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 SUPERFAMILY SSF55120 48 237 1.55E-39 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 SMART SM00363 1 88 5.5E-4 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06085 2cc8fc1cb90972c9095d3f128324dc9f 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 227 1.1E-41 T 23-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.081 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 Pfam PF00410 Ribosomal protein S8 5 132 6.4E-54 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 PANTHER PTHR11758 1 132 2.0E-68 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 Gene3D G3DSA:3.30.1370.30 2 73 2.1E-30 T 23-04-2016 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 Gene3D G3DSA:3.30.1490.10 76 132 3.8E-30 T 23-04-2016 SPYM18_RS00440 a2714d7a3562f4bd0f3f19b68577d195 132 SUPERFAMILY SSF56047 2 132 2.09E-49 T 23-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 SUPERFAMILY SSF161098 280 480 1.96E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 Gene3D G3DSA:1.10.3720.10 281 485 7.9E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465:SF0 145 170 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465:SF0 62 78 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465:SF0 1 44 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465:SF0 264 493 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 299 492 4.4E-35 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465 145 170 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465 62 78 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465 1 44 1.9E-68 T 23-04-2016 SPYM18_RS01345 63874d07084c5fcad6fb39c86fd65992 500 PANTHER PTHR30465 264 493 1.9E-68 T 23-04-2016 SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 8 102 2.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 139 274 2.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 374 514 2.2E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 531 587 6.7E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 344 358 6.7E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 PANTHER PTHR19211 1 578 0.0 T 23-04-2016 SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 PANTHER PTHR19211:SF64 1 578 0.0 T 23-04-2016 SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 275 299 1.1E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Gene3D G3DSA:3.40.50.300 359 373 1.1E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 SMART SM00382 28 239 2.5E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 SMART SM00382 351 518 3.4E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 SUPERFAMILY SSF52540 12 237 1.11E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Pfam PF12848 ABC transporter 232 314 4.7E-24 T 23-04-2016 IPR032781 ABC-transporter extension domain SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 SUPERFAMILY SSF52540 308 534 1.18E-40 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Pfam PF00005 ABC transporter 344 472 7.9E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04355 3d4b71d167630b10e3fac89a9c1b6cb2 635 Pfam PF00005 ABC transporter 20 191 1.3E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 20 290 4.2E-66 T 23-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 PANTHER PTHR11079 35 296 2.7E-80 T 23-04-2016 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 SUPERFAMILY SSF55120 69 287 8.64E-66 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 PANTHER PTHR11079:SF73 35 296 2.7E-80 T 23-04-2016 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 127 141 - T 23-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS04695 76427c26836d43dc157a89055d9477d5 301 Pfam PF00849 RNA pseudouridylate synthase 84 237 4.0E-31 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 Pfam PF03477 ATP cone domain 15 106 2.4E-20 T 23-04-2016 IPR005144 ATP-cone domain SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 PANTHER PTHR21075 7 727 2.0E-269 T 23-04-2016 SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 131 721 5.5E-180 T 23-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 132 721 3.4E-180 T 23-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 SUPERFAMILY SSF51998 137 703 1.46E-193 T 23-04-2016 SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 ProSitePatterns PS00850 Glycine radical domain signature. 692 700 - T 23-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPYM18_RS09270 07c0bc5bd8296e3584f6b7a6b84bba30 732 Gene3D G3DSA:3.20.70.20 139 702 1.9E-185 T 23-04-2016 SPYM18_RS05605 cff224d0d2611d8bfa06e4f3bcd3bd36 227 Gene3D G3DSA:3.40.50.300 16 111 7.3E-5 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05605 cff224d0d2611d8bfa06e4f3bcd3bd36 227 Pfam PF13479 AAA domain 14 208 1.8E-29 T 23-04-2016 SPYM18_RS05605 cff224d0d2611d8bfa06e4f3bcd3bd36 227 TIGRFAM TIGR01618 phage_P_loop: phage nucleotide-binding protein 2 222 5.7E-87 T 23-04-2016 IPR006505 Streptococcus phage Sfi11, Gp233, NTP-binding SPYM18_RS05605 cff224d0d2611d8bfa06e4f3bcd3bd36 227 SUPERFAMILY SSF52540 15 137 3.13E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 PANTHER PTHR26402 2 215 2.6E-65 T 23-04-2016 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 Pfam PF00072 Response regulator receiver domain 4 112 4.4E-23 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 SMART SM00448 2 112 1.3E-34 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 Gene3D G3DSA:3.40.50.2300 2 124 9.4E-37 T 23-04-2016 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 Gene3D G3DSA:1.10.10.10 125 213 4.5E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 SUPERFAMILY SSF52172 1 175 8.11E-37 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 PANTHER PTHR26402:SF578 2 215 2.6E-65 T 23-04-2016 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 SMART SM00862 143 213 5.4E-21 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS08965 ff960a9a6dc4ce46bde20e6e25b38981 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 213 1.0E-19 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 SUPERFAMILY SSF142887 326 377 1.57E-15 T 23-04-2016 SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 SUPERFAMILY SSF142887 192 244 2.48E-19 T 23-04-2016 SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 195 245 3.1E-27 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 574 602 0.0014 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 331 378 1.9E-19 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 111 132 18.0 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 421 469 8.6E-15 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 73 91 0.0062 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 Pfam PF04270 Streptococcal histidine triad protein 664 721 3.3E-17 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 1 373 2.7E-197 T 23-04-2016 IPR023832 Histidine triad protein SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 TIGRFAM TIGR01363 strep_his_triad: streptococcal histidine triad protein 652 807 6.8E-9 T 23-04-2016 IPR023832 Histidine triad protein SPYM18_RS08925 b6a8f033f8026d6fcba326360a5e0c4d 823 SUPERFAMILY SSF142887 417 468 5.23E-14 T 23-04-2016 SPYM18_RS08130 16b24788b42e6b72c75d00f85586e70b 129 Pfam PF03780 Asp23 family, cell envelope-related function 7 108 8.4E-30 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 SPYM18_RS08130 16b24788b42e6b72c75d00f85586e70b 129 PANTHER PTHR34297:SF1 4 129 5.4E-30 T 23-04-2016 SPYM18_RS08130 16b24788b42e6b72c75d00f85586e70b 129 PANTHER PTHR34297 4 129 5.4E-30 T 23-04-2016 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 PANTHER PTHR33992 1 112 8.9E-32 T 23-04-2016 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 Gene3D G3DSA:3.30.230.10 1 111 1.2E-36 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 96 1.0E-45 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 50 64 - T 23-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 SUPERFAMILY SSF54211 1 111 1.49E-32 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 Pfam PF00825 Ribonuclease P 1 104 2.4E-30 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 106 1.4E-27 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPYM18_RS01135 9fcef22b96b39fa5cdfe1806a526f958 119 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 109 18.597 T 23-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 110 1.0E-27 T 23-04-2016 IPR006504 Transcriptional regulator Spx/MgsR SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 Pfam PF03960 ArsC family 9 109 4.8E-14 T 23-04-2016 IPR006660 Arsenate reductase-like SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 SUPERFAMILY SSF52833 1 110 4.07E-30 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 Gene3D G3DSA:3.40.30.10 1 110 7.1E-38 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 PANTHER PTHR30041 1 109 3.7E-32 T 23-04-2016 SPYM18_RS02055 3ed39b9b166f90f017cee2eacaa0ad1b 118 PANTHER PTHR30041:SF3 1 109 3.7E-32 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 SUPERFAMILY SSF100950 67 229 2.36E-34 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 Gene3D G3DSA:1.10.10.10 5 77 5.0E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 PANTHER PTHR30363:SF16 1 248 5.3E-114 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 SUPERFAMILY SSF46785 2 56 1.26E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 SMART SM00420 3 55 3.5E-16 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 SMART SM01134 66 228 2.6E-58 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 Gene3D G3DSA:3.40.50.1360 78 211 2.1E-18 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 ProSitePatterns PS00894 DeoR-type HTH domain signature. 3 37 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 PANTHER PTHR30363 1 248 5.3E-114 T 23-04-2016 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 Pfam PF00455 DeoR C terminal sensor domain 68 227 5.1E-46 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 Pfam PF08220 DeoR-like helix-turn-helix domain 3 57 4.2E-17 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 21 35 6.4E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS09065 3d0bf82e2ed63a88722528417754cfb8 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 35 53 6.4E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS05960 892600a04845356f883a8a97d3cb30d9 269 Pfam PF13367 Protease prsW family 73 250 4.6E-22 T 23-04-2016 IPR026898 Protease PrsW GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 PANTHER PTHR30614:SF15 19 508 1.2E-143 T 23-04-2016 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Gene3D G3DSA:3.40.190.10 24 116 3.0E-29 T 23-04-2016 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Gene3D G3DSA:3.40.190.10 225 253 3.0E-29 T 23-04-2016 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 SUPERFAMILY SSF161098 289 488 5.89E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Gene3D G3DSA:3.40.190.10 117 211 9.8E-12 T 23-04-2016 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 PANTHER PTHR30614 19 508 1.2E-143 T 23-04-2016 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 SMART SM00062 27 264 8.2E-29 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 254 1.6E-34 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Gene3D G3DSA:1.10.3720.10 288 503 1.1E-55 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 289 397 2.1E-20 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 335 502 1.9E-18 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01280 218e506e64bebffc7ddce4e1a62e7c6e 522 SUPERFAMILY SSF53850 1 254 3.63E-41 T 23-04-2016 SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 PANTHER PTHR33867:SF1 8 163 1.2E-38 T 23-04-2016 SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 Gene3D G3DSA:2.30.30.180 96 162 6.2E-26 T 23-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 SUPERFAMILY SSF75420 8 92 1.01E-24 T 23-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 PANTHER PTHR33867 8 163 1.2E-38 T 23-04-2016 SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 Pfam PF02576 Putative ribosome maturation factor RimP 26 159 3.6E-35 T 23-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 Gene3D G3DSA:3.30.300.70 11 89 1.4E-23 T 23-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 14 164 20.224 T 23-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 SPYM18_RS07445 11030bc12999bf51f43998252897cf45 164 SUPERFAMILY SSF74942 93 163 7.72E-17 T 23-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 PIRSF PIRSF005087 3 139 2.7E-56 T 23-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 Gene3D G3DSA:3.40.50.360 5 133 5.4E-51 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 PANTHER PTHR37297:SF1 4 143 1.2E-37 T 23-04-2016 SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 Pfam PF07972 NrdI Flavodoxin like 7 125 6.5E-46 T 23-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 PANTHER PTHR37297 4 143 1.2E-37 T 23-04-2016 SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 TIGRFAM TIGR00333 nrdI: nrdI protein 7 130 1.4E-50 T 23-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 SUPERFAMILY SSF52218 5 131 5.8E-23 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS02090 fa943405055c3f8b455f3978bf914497 162 Hamap MF_00128 Protein NrdI [nrdI]. 5 135 34.235 T 23-04-2016 IPR020852 Ribonucleotide reductase, class Ib, NrdI, bacterial SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 PANTHER PTHR13767 2 293 4.9E-105 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 SUPERFAMILY SSF55120 1 235 1.01E-73 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 2 215 3.8E-71 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 293 18.345 T 23-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 180 237 2.6E-9 T 23-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 PANTHER PTHR13767:SF2 2 293 4.9E-105 T 23-04-2016 SPYM18_RS05200 b6e21627ac17a39d0772ab0bb5fdba9e 294 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 179 6.2E-53 T 23-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 PANTHER PTHR10046 311 343 4.5E-37 T 23-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 PANTHER PTHR10046 231 295 4.5E-37 T 23-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 SUPERFAMILY SSF50156 111 191 1.65E-5 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 Pfam PF13180 PDZ domain 130 192 1.2E-8 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 233 310 3.5E-6 T 23-04-2016 IPR008269 Peptidase S16, Lon C-terminal GO:0004176|GO:0004252|GO:0006508 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 Gene3D G3DSA:2.30.42.10 131 193 2.9E-7 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 PANTHER PTHR10046:SF48 311 343 4.5E-37 T 23-04-2016 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 PANTHER PTHR10046:SF48 231 295 4.5E-37 T 23-04-2016 SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 Gene3D G3DSA:3.30.230.10 230 343 1.2E-21 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS06695 e1bc009b51a168c16eeef9217a89e5a4 345 SUPERFAMILY SSF54211 163 343 6.07E-22 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS02280 fba7485ccab7ab3b7f8ed0e9eaa36537 190 Gene3D G3DSA:1.20.1560.10 4 188 4.6E-42 T 23-04-2016 SPYM18_RS02280 fba7485ccab7ab3b7f8ed0e9eaa36537 190 Pfam PF00664 ABC transporter transmembrane region 5 187 5.6E-40 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS02280 fba7485ccab7ab3b7f8ed0e9eaa36537 190 SUPERFAMILY SSF90123 4 188 4.05E-37 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS02280 fba7485ccab7ab3b7f8ed0e9eaa36537 190 PANTHER PTHR24221 1 184 2.9E-31 T 23-04-2016 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Pfam PF00231 ATP synthase 4 290 7.1E-83 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 8.8E-36 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 PRINTS PR00126 ATP synthase gamma subunit signature 237 256 8.8E-36 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 PRINTS PR00126 ATP synthase gamma subunit signature 168 185 8.8E-36 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 PRINTS PR00126 ATP synthase gamma subunit signature 268 289 8.8E-36 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 PANTHER PTHR11693 1 291 2.5E-90 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Gene3D G3DSA:3.40.1380.10 67 194 1.8E-40 T 23-04-2016 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Gene3D G3DSA:1.10.287.80 205 238 1.1E-23 T 23-04-2016 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Gene3D G3DSA:1.10.287.80 20 61 1.1E-23 T 23-04-2016 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 290 32.01 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 Gene3D G3DSA:1.10.287.80 239 285 1.3E-26 T 23-04-2016 SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 SUPERFAMILY SSF52943 4 290 1.31E-82 T 23-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 276 289 - T 23-04-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site SPYM18_RS03535 3991365a378f365665b14321c06aa79f 291 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 290 1.0E-97 T 23-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 PIRSF PIRSF005087 2 152 1.7E-39 T 23-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 PANTHER PTHR37297 3 142 8.9E-31 T 23-04-2016 SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 PANTHER PTHR37297:SF1 3 142 8.9E-31 T 23-04-2016 SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 Gene3D G3DSA:3.40.50.360 5 144 3.0E-41 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 SUPERFAMILY SSF52218 1 142 1.26E-18 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS08820 0bb404b8d4f80f5845a29cfd1974dced 152 Pfam PF07972 NrdI Flavodoxin like 6 139 1.7E-39 T 23-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI SPYM18_RS00850 13c6667ac8cd5ac6504bdb7780dc5ea9 332 Pfam PF01992 ATP synthase (C/AC39) subunit 7 326 8.4E-45 T 23-04-2016 IPR002843 ATPase, V0 complex, c/d subunit SPYM18_RS00850 13c6667ac8cd5ac6504bdb7780dc5ea9 332 PANTHER PTHR38682 4 332 1.4E-22 T 23-04-2016 SPYM18_RS00850 13c6667ac8cd5ac6504bdb7780dc5ea9 332 SUPERFAMILY SSF103486 4 329 3.4E-71 T 23-04-2016 IPR002843 ATPase, V0 complex, c/d subunit SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 337 2.1E-77 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 SUPERFAMILY SSF52374 5 337 4.29E-80 T 23-04-2016 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PANTHER PTHR10055 3 339 6.6E-182 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 3.4E-24 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 3.4E-24 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 3.4E-24 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 3.4E-24 T 23-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 Pfam PF00579 tRNA synthetases class I (W and Y) 4 290 4.8E-56 T 23-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 338 35.45 T 23-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 Gene3D G3DSA:3.40.50.620 3 217 5.3E-75 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 PANTHER PTHR10055:SF6 3 339 6.6E-182 T 23-04-2016 SPYM18_RS09595 ae00bf827a9f84546c9a6f4fab9a4bed 340 Gene3D G3DSA:1.10.240.10 218 327 2.9E-37 T 23-04-2016 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SMART SM00388 208 274 1.0E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SUPERFAMILY SSF55874 263 435 1.96E-45 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PANTHER PTHR24423:SF568 77 449 1.3E-176 T 23-04-2016 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 8.1E-20 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 390 8.1E-20 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 434 8.1E-20 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 415 8.1E-20 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 209 273 1.9E-16 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SUPERFAMILY SSF55785 84 200 4.19E-12 T 23-04-2016 IPR000014 PAS domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SMART SM00091 94 160 2.4E-9 T 23-04-2016 IPR000014 PAS domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Pfam PF00989 PAS fold 95 162 2.3E-8 T 23-04-2016 IPR013767 PAS fold GO:0006355 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Gene3D G3DSA:1.10.287.130 200 261 1.2E-19 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Gene3D G3DSA:3.30.565.10 262 437 2.3E-49 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 91 208 2.9E-8 T 23-04-2016 IPR000014 PAS domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 PANTHER PTHR24423 77 449 1.3E-176 T 23-04-2016 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 436 1.2E-27 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 Gene3D G3DSA:3.30.450.20 86 151 9.4E-12 T 23-04-2016 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SUPERFAMILY SSF47384 194 273 2.16E-18 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS02575 a91286e677cf31ce6cf294cc9f19124b 450 SMART SM00387 325 437 2.3E-40 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 238 302 2.4E-27 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Gene3D G3DSA:2.170.120.12 48 168 9.6E-45 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 1.1E-23 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 35.974 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 SUPERFAMILY SSF55257 4 48 1.94E-29 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 SUPERFAMILY SSF55257 170 224 1.94E-29 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 1.6E-20 T 23-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 SUPERFAMILY SSF47789 245 311 3.53E-23 T 23-04-2016 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 SUPERFAMILY SSF56553 48 169 5.49E-41 T 23-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 SMART SM00662 18 225 8.4E-89 T 23-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 309 2.0E-26 T 23-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Gene3D G3DSA:3.30.1360.10 171 225 5.4E-6 T 23-04-2016 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Gene3D G3DSA:3.30.1360.10 11 47 5.4E-6 T 23-04-2016 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 PANTHER PTHR32108:SF0 1 312 1.6E-133 T 23-04-2016 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 310 1.3E-114 T 23-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 Gene3D G3DSA:1.10.150.20 244 311 1.7E-31 T 23-04-2016 SPYM18_RS00495 1b9a22b81aa22e5563adf697a23ddb8c 312 PANTHER PTHR32108 1 312 1.6E-133 T 23-04-2016 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 TIGRFAM TIGR00552 nadE: NAD+ synthetase 18 274 4.7E-72 T 23-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 268 30.071 T 23-04-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 Gene3D G3DSA:3.40.50.620 4 269 2.7E-65 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 SUPERFAMILY SSF52402 3 273 5.1E-84 T 23-04-2016 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 PANTHER PTHR23090:SF7 1 274 6.0E-158 T 23-04-2016 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 PANTHER PTHR23090 1 274 6.0E-158 T 23-04-2016 SPYM18_RS07170 e63da545c748b0ccc1eaf9c9e29b8ba9 274 Pfam PF02540 NAD synthase 23 265 6.1E-65 T 23-04-2016 IPR022310 NAD/GMP synthase SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 Gene3D G3DSA:3.40.50.300 55 272 1.6E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 SUPERFAMILY SSF54211 299 452 8.34E-39 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 SUPERFAMILY SSF54211 251 265 8.34E-39 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 1.5E-189 T 23-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 Pfam PF13481 AAA domain 70 218 3.5E-15 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PANTHER PTHR32472 1 452 2.8E-214 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 SMART SM00382 87 240 4.1E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 SUPERFAMILY SSF52540 68 287 8.99E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 Pfam PF13541 Subunit ChlI of Mg-chelatase 361 425 3.6E-8 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 Gene3D G3DSA:3.30.230.10 284 452 2.0E-34 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 79 107 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 318 341 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 10 34 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 209 237 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 170 194 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 120 137 2.7E-87 T 23-04-2016 SPYM18_RS01100 79a5c4f3e02d524de50b5d6e89bba6ff 453 PRINTS PR01874 DNA repair protein radA signature 244 270 2.7E-87 T 23-04-2016 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 PANTHER PTHR10457 13 283 2.0E-48 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 PRINTS PR00959 Mevalonate kinase family signature 250 267 8.8E-20 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 PRINTS PR00959 Mevalonate kinase family signature 10 34 8.8E-20 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 PRINTS PR00959 Mevalonate kinase family signature 81 103 8.8E-20 T 23-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 Pfam PF08544 GHMP kinases C terminal 204 283 3.7E-15 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 Gene3D G3DSA:3.30.70.890 167 288 3.3E-37 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 SUPERFAMILY SSF54211 1 149 5.09E-31 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 SUPERFAMILY SSF55060 160 290 3.78E-31 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 265 1.7E-78 T 23-04-2016 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|UniPathway: UPA00057 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 Pfam PF00288 GHMP kinases N terminal domain 78 140 8.3E-12 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 Gene3D G3DSA:3.30.230.10 3 48 2.9E-11 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS04025 5229048673d3adac4b10dd2e9ed5a0c2 292 Gene3D G3DSA:3.30.230.10 69 166 4.0E-23 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 PANTHER PTHR10000 1 269 5.9E-98 T 23-04-2016 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 23-04-2016 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 SUPERFAMILY SSF56784 1 268 6.37E-80 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 Gene3D G3DSA:3.30.1240.10 88 182 1.9E-45 T 23-04-2016 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 PANTHER PTHR10000:SF16 1 269 5.9E-98 T 23-04-2016 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 Gene3D G3DSA:3.40.50.1000 183 268 1.9E-59 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 Gene3D G3DSA:3.40.50.1000 1 76 1.9E-59 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 3.9E-71 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 1.7E-30 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 2.5E-65 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS02920 8f4994ed6edeaa03d52071362db63388 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 PANTHER PTHR23135 31 223 9.4E-127 T 23-04-2016 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 PANTHER PTHR23135 253 447 9.4E-127 T 23-04-2016 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 SUPERFAMILY SSF53623 39 190 9.97E-33 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 SUPERFAMILY SSF53623 224 296 9.97E-33 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 PANTHER PTHR23135:SF7 31 223 9.4E-127 T 23-04-2016 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 PANTHER PTHR23135:SF7 253 447 9.4E-127 T 23-04-2016 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 Pfam PF08353 Domain of unknown function (DUF1727) 319 429 2.3E-31 T 23-04-2016 IPR013564 Domain of unknown function DUF1727 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 Gene3D G3DSA:3.40.1190.10 223 299 4.1E-41 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 Gene3D G3DSA:3.40.1190.10 38 189 4.1E-41 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS04400 9f037d1a6d53d0d87acc55c429033ae4 447 Pfam PF08245 Mur ligase middle domain 53 281 2.8E-11 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS08765 2daff7818ad997dcb0e813a4b08665b8 121 PANTHER PTHR33909:SF1 5 107 7.9E-19 T 23-04-2016 SPYM18_RS08765 2daff7818ad997dcb0e813a4b08665b8 121 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 82 2.9E-14 T 23-04-2016 IPR003849 Preprotein translocase YajC SPYM18_RS08765 2daff7818ad997dcb0e813a4b08665b8 121 PANTHER PTHR33909 5 107 7.9E-19 T 23-04-2016 SPYM18_RS08765 2daff7818ad997dcb0e813a4b08665b8 121 Pfam PF02699 Preprotein translocase subunit 5 81 2.9E-19 T 23-04-2016 IPR003849 Preprotein translocase YajC SPYM18_RS08765 2daff7818ad997dcb0e813a4b08665b8 121 SMART SM01323 1 83 3.9E-27 T 23-04-2016 IPR003849 Preprotein translocase YajC SPYM18_RS08755 2ecfbc98f0f787673c6562984602b68a 264 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 223 249 - T 23-04-2016 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00557 SPYM18_RS08755 2ecfbc98f0f787673c6562984602b68a 264 Pfam PF01148 Cytidylyltransferase family 2 261 1.3E-76 T 23-04-2016 SPYM18_RS08755 2ecfbc98f0f787673c6562984602b68a 264 PANTHER PTHR13773 1 261 1.2E-69 T 23-04-2016 SPYM18_RS03295 898a65d85b11b5139dad357926a9f378 1307 Pfam PF10145 Phage-related minor tail protein 206 514 2.0E-16 T 23-04-2016 IPR010090 Phage tail tape measure protein SPYM18_RS03295 898a65d85b11b5139dad357926a9f378 1307 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 164 523 8.0E-75 T 23-04-2016 IPR010090 Phage tail tape measure protein SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SUPERFAMILY SSF52058 396 695 9.86E-43 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 PANTHER PTHR24365 411 695 2.5E-32 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 529 550 22.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 507 528 62.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 638 659 280.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 594 615 340.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 463 484 360.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00365 660 680 170.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SUPERFAMILY SSF142887 142 188 3.79E-12 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SUPERFAMILY SSF142887 66 114 1.01E-11 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SUPERFAMILY SSF142887 209 260 5.49E-13 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Pfam PF04270 Streptococcal histidine triad protein 213 256 5.4E-6 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Pfam PF04270 Streptococcal histidine triad protein 70 109 2.6E-5 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Pfam PF04270 Streptococcal histidine triad protein 145 186 1.1E-10 T 23-04-2016 IPR006270 Streptococcal histidine triad repeat SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00369 507 528 13.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00369 529 551 11.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00369 463 483 320.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Gene3D G3DSA:3.80.10.10 412 569 3.2E-35 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Gene3D G3DSA:3.80.10.10 572 696 5.6E-14 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 Pfam PF12799 Leucine Rich repeats (2 copies) 487 527 6.6E-7 T 23-04-2016 IPR025875 Leucine rich repeat 4 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00364 463 482 460.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00364 529 548 14.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00364 507 526 38.0 T 23-04-2016 SPYM18_RS05940 7204846fbb992f5a1f3a6c5243f0987d 792 SMART SM00364 638 657 48.0 T 23-04-2016 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 PANTHER PTHR11692:SF2 1 515 8.2E-293 T 23-04-2016 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 SMART SM00798 134 450 8.1E-186 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 449 4.8E-115 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Gene3D G3DSA:3.40.50.1380 2 186 4.3E-81 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Pfam PF02142 MGS-like domain 14 128 2.0E-23 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 PANTHER PTHR11692 1 515 8.2E-293 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Gene3D G3DSA:3.40.140.20 239 359 3.1E-46 T 23-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 SMART SM00851 14 129 1.7E-46 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 SUPERFAMILY SSF52335 2 194 3.89E-67 T 23-04-2016 IPR011607 Methylglyoxal synthase-like domain SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 515 44.096 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 Gene3D G3DSA:3.40.140.20 366 505 1.3E-55 T 23-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 SUPERFAMILY SSF53927 208 515 4.21E-120 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 515 1.4E-212 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS00290 415a6406d9bed66625612efbf5683ed9 515 PIRSF PIRSF000414 1 515 1.8E-206 T 23-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 337 38.219 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 PANTHER PTHR23132:SF8 1 344 1.5E-149 T 23-04-2016 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Gene3D G3DSA:3.30.470.20 118 143 7.0E-49 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Gene3D G3DSA:3.30.470.20 213 336 7.0E-49 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 279 307 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 SUPERFAMILY SSF56059 127 336 6.01E-57 T 23-04-2016 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 94 105 - T 23-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Gene3D G3DSA:3.30.1490.20 145 210 3.9E-22 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Pfam PF07478 D-ala D-ala ligase C-terminus 135 334 7.1E-70 T 23-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 PIRSF PIRSF039102 1 345 1.2E-99 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 PANTHER PTHR23132 1 344 1.5E-149 T 23-04-2016 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 SUPERFAMILY SSF52440 3 126 1.82E-30 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Gene3D G3DSA:3.40.50.20 1 116 6.9E-31 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 336 2.9E-99 T 23-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06175 5c00fed641526870448e61602e7f808d 348 Pfam PF01820 D-ala D-ala ligase N-terminus 6 116 1.0E-24 T 23-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.6E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PANTHER PTHR24322:SF462 10 138 3.7E-72 T 23-04-2016 SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PANTHER PTHR24322:SF462 154 186 3.7E-72 T 23-04-2016 SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 Gene3D G3DSA:3.40.50.720 5 257 3.3E-80 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 257 1.6E-62 T 23-04-2016 SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 SUPERFAMILY SSF51735 6 258 4.61E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PANTHER PTHR24322 10 138 3.7E-72 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PANTHER PTHR24322 154 186 3.7E-72 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.8E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.8E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.8E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07120 f60ec72b6393635fd1aa3cf8553e7b49 259 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 6 259 1.1E-108 T 23-04-2016 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 SUPERFAMILY SSF52161 6 144 3.14E-56 T 23-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 17 143 25.896 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 Pfam PF00572 Ribosomal protein L13 16 140 6.9E-53 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 Gene3D G3DSA:3.90.1180.10 5 143 5.1E-61 T 23-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 PANTHER PTHR11545 4 144 5.8E-69 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 144 3.6E-58 T 23-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 PIRSF PIRSF002181 1 147 2.1E-46 T 23-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08625 0550296232a991a2b80183c0ac332fc6 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 129 - T 23-04-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 280 312 4.2E-6 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 Pfam PF01391 Collagen triple helix repeat (20 copies) 159 217 6.7E-10 T 23-04-2016 IPR008160 Collagen triple helix repeat SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 Pfam PF00746 Gram positive anchor 277 310 2.6E-9 T 23-04-2016 IPR019948 Gram-positive anchor SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 275 290 1.9E-14 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 291 311 1.9E-14 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PANTHER PTHR24023:SF512 253 273 1.9E-24 T 23-04-2016 SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PANTHER PTHR24023:SF512 90 218 1.9E-24 T 23-04-2016 SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PANTHER PTHR24023 253 273 1.9E-24 T 23-04-2016 SPYM18_RS04450 05a98abda9d86dfbabb0ba72158e3d29 315 PANTHER PTHR24023 90 218 1.9E-24 T 23-04-2016 SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 322 2.7E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 Pfam PF07730 Histidine kinase 132 200 1.8E-16 T 23-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 Gene3D G3DSA:3.30.565.10 166 190 2.7E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 Gene3D G3DSA:3.30.565.10 234 329 2.7E-9 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 SUPERFAMILY SSF55874 209 326 1.78E-14 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 PANTHER PTHR24421:SF1 56 334 4.8E-50 T 23-04-2016 SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 PANTHER PTHR24421 56 334 4.8E-50 T 23-04-2016 SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 PIRSF PIRSF037431 1 334 7.8E-125 T 23-04-2016 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 SPYM18_RS07050 a46c78cf8703b29da03f8cdb27c540ef 334 SMART SM00387 236 329 0.0087 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS00045 3832f1b99e105d53c33b58f26b87575a 428 SUPERFAMILY SSF56601 99 426 5.42E-33 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS00045 3832f1b99e105d53c33b58f26b87575a 428 Pfam PF13354 Beta-lactamase enzyme family 213 405 4.2E-30 T 23-04-2016 SPYM18_RS00045 3832f1b99e105d53c33b58f26b87575a 428 Gene3D G3DSA:3.40.710.10 191 427 9.3E-45 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 PANTHER PTHR35336 7 158 4.5E-80 T 23-04-2016 SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 SUPERFAMILY SSF101307 7 158 2.75E-51 T 23-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 PIRSF PIRSF019587 2 166 1.4E-72 T 23-04-2016 IPR026038 Putative phosphatidylglycerophosphatase SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 Gene3D G3DSA:1.10.3760.10 3 167 2.5E-75 T 23-04-2016 IPR027416 YutG-like domain SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 Pfam PF04608 Phosphatidylglycerophosphatase A 20 156 8.5E-20 T 23-04-2016 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 SPYM18_RS09025 644acee1035ee5242db93e70471a5899 169 PANTHER PTHR35336:SF1 7 158 4.5E-80 T 23-04-2016 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 Gene3D G3DSA:3.55.30.10 1 232 3.1E-72 T 23-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 289 37.325 T 23-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 Gene3D G3DSA:3.90.1280.10 233 288 2.9E-27 T 23-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 PIRSF PIRSF005261 1 290 5.0E-74 T 23-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 Pfam PF01430 Hsp33 protein 2 278 2.8E-79 T 23-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 PANTHER PTHR30111 1 288 9.7E-83 T 23-04-2016 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 SUPERFAMILY SSF64397 1 239 4.19E-63 T 23-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 SUPERFAMILY SSF118352 230 288 1.96E-21 T 23-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 SPYM18_RS00740 d92e381ffa0334b0a660ea0e17dfd80e 290 PANTHER PTHR30111:SF1 1 288 9.7E-83 T 23-04-2016 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 Hamap MF_01235 Putative N-acetylmannosamine-6-phosphate 2-epimerase [nanE]. 12 233 39.696 T 23-04-2016 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9|UniPathway: UPA00629 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 PANTHER PTHR36204 3 234 2.5E-103 T 23-04-2016 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 SUPERFAMILY SSF51366 12 232 1.06E-52 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 Pfam PF04131 Putative N-acetylmannosamine-6-phosphate epimerase 38 234 1.1E-89 T 23-04-2016 IPR007260 Putative N-acetylmannosamine-6-phosphate epimerase GO:0006051|GO:0047465 KEGG: 00520+5.1.3.9|UniPathway: UPA00629 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 PANTHER PTHR36204:SF1 3 234 2.5E-103 T 23-04-2016 SPYM18_RS01155 068b51399841e50ae7d016fe2544ce8d 234 Gene3D G3DSA:3.20.20.70 6 233 6.8E-95 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02865 c60c2c0f97701880d88b1f2bae9376b4 282 SUPERFAMILY SSF51445 69 272 6.74E-35 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS02865 c60c2c0f97701880d88b1f2bae9376b4 282 Gene3D G3DSA:3.20.20.80 67 261 2.5E-36 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS02865 c60c2c0f97701880d88b1f2bae9376b4 282 Pfam PF01183 Glycosyl hydrolases family 25 69 253 2.5E-14 T 23-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 SPYM18_RS02865 c60c2c0f97701880d88b1f2bae9376b4 282 PANTHER PTHR34135 67 274 9.1E-43 T 23-04-2016 SPYM18_RS02865 c60c2c0f97701880d88b1f2bae9376b4 282 PANTHER PTHR34135:SF2 67 274 9.1E-43 T 23-04-2016 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 Gene3D G3DSA:3.40.1010.10 14 123 6.7E-12 T 23-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 Gene3D G3DSA:3.30.950.10 124 235 1.6E-37 T 23-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 285 8.9E-78 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 PANTHER PTHR21091 9 232 1.1E-82 T 23-04-2016 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 PANTHER PTHR21091:SF18 9 232 1.1E-82 T 23-04-2016 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 PIRSF PIRSF005917 3 287 2.5E-93 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.522 T 23-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 23-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 SUPERFAMILY SSF53790 14 231 2.62E-77 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 SPYM18_RS02040 5018df027ea5747e67cfef3197e44a7f 287 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 214 5.9E-21 T 23-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 SPYM18_RS09500 016b93a09fb43ec33b37ab34484a6469 98 ProSitePatterns PS00893 Nudix box signature. 23 44 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPYM18_RS09500 016b93a09fb43ec33b37ab34484a6469 98 Gene3D G3DSA:3.90.79.10 2 81 2.3E-16 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS09500 016b93a09fb43ec33b37ab34484a6469 98 SUPERFAMILY SSF55811 2 81 3.11E-13 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS07700 311affdee6ce4ecbc9c055a97a900731 134 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 2 131 4.5E-34 T 23-04-2016 IPR010024 Conserved hypothetical protein CHP1671 SPYM18_RS07700 311affdee6ce4ecbc9c055a97a900731 134 Gene3D G3DSA:2.30.30.290 60 127 6.1E-16 T 23-04-2016 IPR023385 YopX-like domain, beta barrel type SPYM18_RS07700 311affdee6ce4ecbc9c055a97a900731 134 SUPERFAMILY SSF159006 1 130 1.02E-26 T 23-04-2016 SPYM18_RS07700 311affdee6ce4ecbc9c055a97a900731 134 Pfam PF09643 YopX protein 4 131 1.9E-24 T 23-04-2016 IPR019096 YopX protein SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PANTHER PTHR11469 57 447 6.7E-147 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 436 24.099 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 23-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 Gene3D G3DSA:3.40.50.10490 70 200 6.4E-27 T 23-04-2016 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 2.4E-24 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 23-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 SUPERFAMILY SSF53697 6 448 1.56E-132 T 23-04-2016 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 Pfam PF00342 Phosphoglucose isomerase 77 426 2.9E-23 T 23-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS01050 f540ab93522ba73f62104d15ca2394d2 449 Gene3D G3DSA:3.40.50.10490 201 418 1.0E-91 T 23-04-2016 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 Gene3D G3DSA:3.40.50.20 5 110 2.1E-34 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 351 40.121 T 23-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 SUPERFAMILY SSF56059 101 296 1.3E-52 T 23-04-2016 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 356 1.3E-108 T 23-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 SUPERFAMILY SSF52440 4 87 1.19E-24 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 PANTHER PTHR11609:SF5 3 356 3.5E-128 T 23-04-2016 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 Pfam PF02222 ATP-grasp domain 111 276 5.9E-46 T 23-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 PANTHER PTHR11609 3 356 3.5E-128 T 23-04-2016 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 Gene3D G3DSA:3.30.470.20 140 356 1.6E-78 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS00310 ede9c2ddcdde48d2e56507ad3514e7fe 357 SUPERFAMILY SSF51246 300 356 1.65E-16 T 23-04-2016 IPR011054 Rudiment single hybrid motif SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 Gene3D G3DSA:3.40.630.30 37 132 6.3E-9 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 SUPERFAMILY SSF55729 34 116 4.48E-8 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 SMART SM00764 147 329 3.7E-121 T 23-04-2016 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 148 183 8.1E-8 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 TIGRFAM TIGR00124 cit_ly_ligase: [citrate (pro-3S)-lyase] ligase 12 331 1.1E-90 T 23-04-2016 IPR005216 Citrate lyase ligase GO:0008771 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 PIRSF PIRSF005751 1 347 3.3E-134 T 23-04-2016 IPR005216 Citrate lyase ligase GO:0008771 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 SUPERFAMILY SSF52374 299 330 1.16E-17 T 23-04-2016 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 SUPERFAMILY SSF52374 146 265 1.16E-17 T 23-04-2016 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 Pfam PF08218 Citrate lyase ligase C-terminal domain 147 329 1.0E-79 T 23-04-2016 IPR013166 Citrate lyase ligase, C-terminal GO:0008771 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 Gene3D G3DSA:3.40.50.620 133 329 1.4E-27 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 123 328 5.0E-119 T 23-04-2016 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 PANTHER PTHR40599:SF1 1 350 3.6E-139 T 23-04-2016 SPYM18_RS04950 9524e3f52d0ebe5d8bdd08e3a7b8d7f3 350 PANTHER PTHR40599 1 350 3.6E-139 T 23-04-2016 SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 PIRSF PIRSF015601 1 245 2.0E-49 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 PANTHER PTHR30027:SF3 1 249 3.2E-69 T 23-04-2016 SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 SUPERFAMILY SSF75217 69 244 1.05E-49 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 SUPERFAMILY SSF88697 2 60 3.48E-8 T 23-04-2016 IPR015947 PUA-like domain SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 Gene3D G3DSA:3.40.1280.10 1 244 6.6E-69 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 PANTHER PTHR30027 1 249 3.2E-69 T 23-04-2016 SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 244 3.3E-46 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS08835 4cad557b95b6d9a26aa782b6b77f1d02 249 Pfam PF04452 RNA methyltransferase 14 241 2.2E-68 T 23-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 SMART SM01149 24 420 1.3E-272 T 23-04-2016 IPR008313 Meiotically up-regulated gene 157 protein SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 PANTHER PTHR31047 7 422 8.9E-189 T 23-04-2016 SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 Gene3D G3DSA:1.50.10.10 8 423 1.8E-174 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 SUPERFAMILY SSF48208 4 424 1.25E-174 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 Pfam PF06824 Protein of unknown function (DUF1237) 25 419 1.5E-149 T 23-04-2016 IPR008313 Meiotically up-regulated gene 157 protein SPYM18_RS06920 0dfdc8203dbb1297e84bd7d670087e87 428 PIRSF PIRSF028846 1 428 6.5E-216 T 23-04-2016 IPR008313 Meiotically up-regulated gene 157 protein SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Gene3D G3DSA:3.30.1360.40 234 330 2.2E-34 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 808 28.907 T 23-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Gene3D G3DSA:1.10.268.10 361 460 5.0E-37 T 23-04-2016 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 PANTHER PTHR10169 2 774 0.0 T 23-04-2016 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 469 9.0E-156 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 SUPERFAMILY SSF101904 497 809 1.31E-105 T 23-04-2016 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Gene3D G3DSA:3.90.199.10 32 214 1.5E-83 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 SUPERFAMILY SSF56719 29 484 2.62E-175 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 804 0.0 T 23-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Gene3D G3DSA:2.120.10.90 494 804 2.6E-123 T 23-04-2016 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 758 804 5.8E-12 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 654 9.1E-10 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 707 754 1.1E-11 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 547 8.8E-10 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 657 703 1.0E-14 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 599 3.4E-12 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 SMART SM00434 9 462 9.1E-281 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04810 a7b8ad97684b4822c6e2215a96f02640 828 PANTHER PTHR10169:SF48 2 774 0.0 T 23-04-2016 SPYM18_RS01970 2553e95e1d9ca78c998ad88e81f623c1 217 Pfam PF08820 Domain of unknown function (DUF1803) 4 93 2.3E-34 T 23-04-2016 IPR014924 Protein of unknown function DUF1803 SPYM18_RS00875 e28b18f5034a5515ccf6935e6c3ae81e 420 Pfam PF05816 Toxic anion resistance protein (TelA) 64 386 3.1E-19 T 23-04-2016 IPR008863 Toxic anion resistance SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 Pfam PF05103 DivIVA protein 6 59 1.6E-15 T 23-04-2016 IPR007793 DivIVA family SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 PANTHER PTHR35794 1 108 3.7E-37 T 23-04-2016 SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 PANTHER PTHR35794:SF1 1 108 3.7E-37 T 23-04-2016 SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 7 39 1.0E-14 T 23-04-2016 IPR019933 DivIVA domain SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 PIRSF PIRSF029938 1 108 4.1E-46 T 23-04-2016 IPR011229 Cell cycle protein GpsB SPYM18_RS07145 ecb74c2b50bb78497fb0111fd451b86f 108 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 104 24.337 T 23-04-2016 IPR011229 Cell cycle protein GpsB SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 PIRSF PIRSF005814 1 779 3.1E-249 T 23-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SUPERFAMILY SSF160443 702 778 1.24E-10 T 23-04-2016 IPR002625 Smr domain SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SMART SM00463 701 779 9.1E-21 T 23-04-2016 IPR002625 Smr domain SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 PANTHER PTHR11361:SF14 5 593 2.4E-213 T 23-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 Gene3D G3DSA:3.40.50.300 288 506 6.2E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 Pfam PF00488 MutS domain V 324 505 6.0E-35 T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SUPERFAMILY SSF48334 34 277 2.88E-24 T 23-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 778 19.582 T 23-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 Pfam PF01713 Smr domain 704 778 1.3E-20 T 23-04-2016 IPR002625 Smr domain SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SUPERFAMILY SSF52540 287 507 8.59E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 403 419 - T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 778 7.9E-212 T 23-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 PANTHER PTHR11361 5 593 2.4E-213 T 23-04-2016 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SMART SM00534 321 506 1.6E-65 T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS08205 15cfc3a83d255c4614c9c76625074d2d 779 SMART SM00533 13 310 1.1E-5 T 23-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 PANTHER PTHR13754 1 267 1.7E-101 T 23-04-2016 SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 Pfam PF00753 Metallo-beta-lactamase superfamily 15 223 3.1E-19 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 SUPERFAMILY SSF56281 12 252 1.57E-45 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 SMART SM00849 16 223 2.3E-10 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 PANTHER PTHR13754:SF15 1 267 1.7E-101 T 23-04-2016 SPYM18_RS02580 68be4b948c790ed306586a66f0af6ca7 269 Gene3D G3DSA:3.60.15.10 5 236 8.9E-40 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS02710 5cd4492e6f7d91bd341432453c1c56c2 161 Gene3D G3DSA:3.30.930.10 3 78 2.1E-5 T 23-04-2016 SPYM18_RS02710 5cd4492e6f7d91bd341432453c1c56c2 161 Gene3D G3DSA:3.30.930.10 115 147 2.1E-5 T 23-04-2016 SPYM18_RS02710 5cd4492e6f7d91bd341432453c1c56c2 161 SUPERFAMILY SSF55681 3 152 1.99E-9 T 23-04-2016 SPYM18_RS07510 deda8cddcb6c0e759ae09d6537165d40 332 SMART SM00892 88 330 2.0E-4 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS07510 deda8cddcb6c0e759ae09d6537165d40 332 Pfam PF01223 DNA/RNA non-specific endonuclease 86 270 1.8E-18 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS04780 f292e0acfeca91300cd5fdfae43b5def 325 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 321 4.5E-32 T 23-04-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 PIRSF PIRSF004793 15 275 1.0E-85 T 23-04-2016 IPR014046 Diadenylate cyclase-like SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 PANTHER PTHR34185 1 283 1.3E-96 T 23-04-2016 SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 Gene3D G3DSA:3.40.1700.10 122 250 5.8E-53 T 23-04-2016 SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 SUPERFAMILY SSF143597 51 249 1.44E-65 T 23-04-2016 SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 128 245 9.4E-43 T 23-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 PANTHER PTHR34185:SF1 1 283 1.3E-96 T 23-04-2016 SPYM18_RS04405 af2d9b75caacf7446609dc416b688b21 283 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 25 261 6.6E-80 T 23-04-2016 IPR014046 Diadenylate cyclase-like SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Pfam PF00929 Exonuclease 11 163 1.3E-24 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SMART SM00479 8 172 3.7E-35 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SMART SM00491 659 785 8.2E-11 T 23-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 PANTHER PTHR30231 7 464 1.3E-132 T 23-04-2016 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 6 173 8.1E-27 T 23-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.40.50.300 573 599 4.4E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.40.50.300 262 335 4.4E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.40.50.300 407 458 4.4E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 PANTHER PTHR30231:SF8 7 464 1.3E-132 T 23-04-2016 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Pfam PF00270 DEAD/DEAH box helicase 254 309 3.5E-5 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.30.420.10 7 175 9.9E-47 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.40.50.300 621 716 6.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Gene3D G3DSA:3.40.50.300 749 782 6.7E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SUPERFAMILY SSF52540 613 779 9.91E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SUPERFAMILY SSF52540 267 312 9.91E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SUPERFAMILY SSF52540 396 465 9.91E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SUPERFAMILY SSF52540 571 585 9.91E-27 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SMART SM00487 242 611 0.0017 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 Pfam PF13307 Helicase C-terminal domain 647 794 6.7E-26 T 23-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 SPYM18_RS03035 bce7bb27b5f8c9750a9563e3884a839d 819 SUPERFAMILY SSF53098 8 232 2.16E-47 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 Gene3D G3DSA:1.10.260.40 1 59 4.5E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 Gene3D G3DSA:2.10.109.10 143 230 4.5E-18 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 SUPERFAMILY SSF47413 2 61 8.45E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 SMART SM00530 6 61 2.8E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 Pfam PF01381 Helix-turn-helix 7 58 9.9E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 PANTHER PTHR10245:SF32 2 232 2.8E-13 T 23-04-2016 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 Pfam PF00717 Peptidase S24-like 148 208 2.7E-12 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 PANTHER PTHR10245 2 232 2.8E-13 T 23-04-2016 SPYM18_RS04965 35eb46aef4ba48f83f55a536100b9099 232 SUPERFAMILY SSF51306 111 228 7.33E-24 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS09320 7c2518547c64752107a0bf6e3db3084b 406 PANTHER PTHR23517 1 394 1.4E-47 T 23-04-2016 SPYM18_RS09320 7c2518547c64752107a0bf6e3db3084b 406 SUPERFAMILY SSF103473 18 401 1.96E-45 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS09320 7c2518547c64752107a0bf6e3db3084b 406 Pfam PF07690 Major Facilitator Superfamily 18 367 9.7E-33 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS09320 7c2518547c64752107a0bf6e3db3084b 406 Gene3D G3DSA:1.20.1250.20 216 399 3.0E-14 T 23-04-2016 SPYM18_RS09320 7c2518547c64752107a0bf6e3db3084b 406 Gene3D G3DSA:1.20.1250.20 17 194 9.1E-23 T 23-04-2016 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 SUPERFAMILY SSF54843 6 114 1.06E-44 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 Gene3D G3DSA:3.90.470.10 6 114 6.9E-45 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 9 111 1.9E-45 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 87 111 - T 23-04-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 PANTHER PTHR13501 1 113 1.2E-49 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 114 29.894 T 23-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00395 bae3cf23e21fea2fdf5fe8a3b546ce39 114 Pfam PF00237 Ribosomal protein L22p/L17e 12 111 3.6E-35 T 23-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PANTHER PTHR11777 1 872 0.0 T 23-04-2016 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 Pfam PF02272 DHHA1 domain 804 869 6.3E-12 T 23-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 SMART SM00863 656 699 7.7E-21 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 2.0E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 2.0E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 2.0E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 2.0E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 2.0E-29 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 698 8.8E-19 T 23-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 855 4.3E-283 T 23-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 872 167.468 T 23-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 SUPERFAMILY SSF55681 5 248 4.72E-79 T 23-04-2016 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 SUPERFAMILY SSF101353 249 441 3.27E-64 T 23-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 PANTHER PTHR11777:SF9 1 872 0.0 T 23-04-2016 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 Gene3D G3DSA:3.30.930.10 4 244 4.2E-86 T 23-04-2016 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 Pfam PF01411 tRNA synthetases class II (A) 8 559 1.2E-180 T 23-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 SUPERFAMILY SSF55186 555 713 1.01E-50 T 23-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 SPYM18_RS06055 72e3749ab416d20f399f07b78a448ad0 872 SUPERFAMILY SSF50447 463 554 4.24E-13 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS06725 6aaa34e25969a9a7985242eb9c4b2559 497 Pfam PF03606 C4-dicarboxylate anaerobic carrier 11 495 4.1E-175 T 23-04-2016 IPR018385 C4-dicarboxylate anaerobic carrier-like GO:0016021 SPYM18_RS06725 6aaa34e25969a9a7985242eb9c4b2559 497 PANTHER PTHR10283 4 273 5.6E-143 T 23-04-2016 SPYM18_RS06725 6aaa34e25969a9a7985242eb9c4b2559 497 PANTHER PTHR10283 300 493 5.6E-143 T 23-04-2016 SPYM18_RS06725 6aaa34e25969a9a7985242eb9c4b2559 497 PANTHER PTHR10283:SF90 4 273 5.6E-143 T 23-04-2016 SPYM18_RS06725 6aaa34e25969a9a7985242eb9c4b2559 497 PANTHER PTHR10283:SF90 300 493 5.6E-143 T 23-04-2016 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 Pfam PF00459 Inositol monophosphatase family 4 233 1.5E-38 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PANTHER PTHR20854 1 238 1.9E-46 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 Gene3D G3DSA:3.40.190.80 156 237 1.6E-11 T 23-04-2016 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 SUPERFAMILY SSF56655 3 244 2.75E-52 T 23-04-2016 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PANTHER PTHR20854:SF4 1 238 1.9E-46 T 23-04-2016 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 Gene3D G3DSA:3.30.540.10 3 155 1.1E-35 T 23-04-2016 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS05180 11b877b19e31eb74194c6f53347c0cc8 262 PRINTS PR00377 Inositol monophosphatase superfamily signature 171 192 5.5E-18 T 23-04-2016 IPR000760 Inositol monophosphatase GO:0046854 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 415 40.565 T 23-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 PANTHER PTHR11063:SF8 1 416 2.9E-171 T 23-04-2016 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Gene3D G3DSA:3.40.309.10 225 373 3.1E-43 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 SUPERFAMILY SSF53720 2 415 1.44E-111 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Gene3D G3DSA:3.40.605.10 374 415 2.3E-99 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Gene3D G3DSA:3.40.605.10 2 222 2.3E-99 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Pfam PF00171 Aldehyde dehydrogenase family 11 283 9.1E-13 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 Pfam PF00171 Aldehyde dehydrogenase family 301 378 1.1E-6 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 405 1.0E-153 T 23-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 344 - T 23-04-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 PIRSF PIRSF000151 1 416 2.7E-176 T 23-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 SPYM18_RS07235 75f10a81157d07d69887281b1962cfa2 416 PANTHER PTHR11063 1 416 2.9E-171 T 23-04-2016 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 3.3E-55 T 23-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 23-04-2016 IPR018201 Beta-ketoacyl synthase, active site SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 406 2.2E-169 T 23-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 Gene3D G3DSA:3.40.47.10 263 409 8.3E-53 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 PANTHER PTHR11712 4 406 3.9E-173 T 23-04-2016 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 SUPERFAMILY SSF53901 214 407 4.02E-63 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 PIRSF PIRSF000447 1 410 2.4E-177 T 23-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 Gene3D G3DSA:3.40.47.10 4 259 1.0E-72 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 SMART SM00825 Beta-ketoacyl synthase 6 399 9.4E-13 T 23-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 SUPERFAMILY SSF53901 4 251 5.21E-71 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS07870 2fa10802153451897cdb5f0814419ab9 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 364 5.4E-31 T 23-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal SPYM18_RS05780 c7c20fee87cfb1c0916f133abec03752 144 Pfam PF11687 Domain of unknown function (DUF3284) 1 121 2.9E-30 T 23-04-2016 IPR021701 Protein of unknown function DUF3284 SPYM18_RS05780 c7c20fee87cfb1c0916f133abec03752 144 SUPERFAMILY SSF55961 33 140 1.07E-6 T 23-04-2016 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 467 8.9E-147 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 PANTHER PTHR10169 4 819 0.0 T 23-04-2016 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 4 742 0.0 T 23-04-2016 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 3 819 33.25 T 23-04-2016 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 SUPERFAMILY SSF56719 27 482 8.11E-164 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 699 1.8E-12 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 546 596 0.05 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 704 731 6.8E-4 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 605 650 4.7E-5 T 23-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Gene3D G3DSA:3.30.1360.40 232 328 1.5E-34 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Gene3D G3DSA:2.120.10.90 495 814 1.5E-64 T 23-04-2016 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 SUPERFAMILY SSF101904 496 814 3.01E-67 T 23-04-2016 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 SMART SM00434 7 460 3.6E-254 T 23-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 PANTHER PTHR10169:SF47 4 819 0.0 T 23-04-2016 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Gene3D G3DSA:3.90.199.10 329 394 8.0E-115 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 SPYM18_RS04175 c6b35d1ecc94d3d83f11c5cd3a66a3d9 819 Gene3D G3DSA:3.90.199.10 26 231 8.0E-115 T 23-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 Pfam PF00654 Voltage gated chloride channel 71 416 1.1E-82 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PRINTS PR00762 Chloride channel signature 366 382 3.5E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PRINTS PR00762 Chloride channel signature 384 403 3.5E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PRINTS PR00762 Chloride channel signature 83 100 3.5E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PRINTS PR00762 Chloride channel signature 163 182 3.5E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PRINTS PR00762 Chloride channel signature 331 351 3.5E-23 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 SUPERFAMILY SSF81340 7 432 1.23E-103 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PANTHER PTHR11689:SF96 22 451 3.2E-77 T 23-04-2016 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 Gene3D G3DSA:1.10.3080.10 2 430 1.8E-84 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS04635 c4fd3457f9979d4c5464369bbcebeee3 510 PANTHER PTHR11689 22 451 3.2E-77 T 23-04-2016 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 12 95 26.503 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 TIGRFAM TIGR00062 L27: ribosomal protein bL27 12 92 2.2E-37 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 Gene3D G3DSA:2.40.50.100 31 95 2.6E-30 T 23-04-2016 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 PANTHER PTHR15893 6 96 5.9E-45 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 ProSitePatterns PS00831 Ribosomal protein L27 signature. 45 59 - T 23-04-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 PRINTS PR00063 Ribosomal protein L27 signature 40 64 3.1E-36 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 PRINTS PR00063 Ribosomal protein L27 signature 65 89 3.1E-36 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 PRINTS PR00063 Ribosomal protein L27 signature 15 39 3.1E-36 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 SUPERFAMILY SSF110324 13 94 2.58E-31 T 23-04-2016 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 Pfam PF01016 Ribosomal L27 protein 13 92 1.2E-33 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03810 dcc8a6f51969378b77392d11a076f5a3 97 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 39 80 9.0E-18 T 23-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 PANTHER PTHR22789:SF8 1 233 2.7E-139 T 23-04-2016 SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 SMART SM01007 10 200 8.4E-70 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 SUPERFAMILY SSF53639 5 225 1.55E-72 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 198 4.6E-46 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 Gene3D G3DSA:3.40.225.10 5 233 1.4E-73 T 23-04-2016 IPR001303 Class II aldolase/adducin N-terminal SPYM18_RS00965 6b004a22d7dab3bfee42044cccd3ed9c 234 PANTHER PTHR22789 1 233 2.7E-139 T 23-04-2016 SPYM18_RS01555 3c0cb879a213e72f61de5d31f714fbb7 116 Gene3D G3DSA:1.10.260.40 6 110 5.2E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01555 3c0cb879a213e72f61de5d31f714fbb7 116 Pfam PF01381 Helix-turn-helix 8 60 8.9E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS01555 3c0cb879a213e72f61de5d31f714fbb7 116 SMART SM00530 7 60 5.7E-8 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS01555 3c0cb879a213e72f61de5d31f714fbb7 116 SUPERFAMILY SSF47413 6 66 2.65E-9 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 Gene3D G3DSA:3.40.50.300 3 213 5.8E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 SMART SM00382 28 215 5.8E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 PANTHER PTHR24220 5 207 3.7E-63 T 23-04-2016 SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 Pfam PF00005 ABC transporter 19 165 2.5E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS00605 e2821b8b80524b364cdb740c3f5521ce 239 SUPERFAMILY SSF52540 3 215 4.35E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 SUPERFAMILY SSF54001 20 139 8.73E-7 T 23-04-2016 SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 Pfam PF08230 Cpl-7 lysozyme C-terminal domain 155 191 3.5E-14 T 23-04-2016 IPR013168 Cpl-7 lysozyme, C-terminal SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 Pfam PF05382 Bacteriophage peptidoglycan hydrolase 5 145 9.3E-62 T 23-04-2016 IPR008044 Bacteriophage lysin SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 SMART SM00047 208 345 2.6E-5 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 Gene3D G3DSA:3.90.1720.10 17 141 1.6E-8 T 23-04-2016 IPR000064 Endopeptidase, NLPC/P60 domain KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 SMART SM01095 154 192 1.5E-20 T 23-04-2016 IPR013168 Cpl-7 lysozyme, C-terminal SPYM18_RS01805 d64bec36c06bfa0784aaf38cf054dde2 405 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 225 318 9.6E-6 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS06760 8cf9ab0a7a512fc822f7dd85bc373e06 359 Pfam PF04237 YjbR 124 222 3.6E-16 T 23-04-2016 IPR007351 Uncharacterised protein YjbR SPYM18_RS06760 8cf9ab0a7a512fc822f7dd85bc373e06 359 SUPERFAMILY SSF142906 103 241 8.63E-30 T 23-04-2016 SPYM18_RS06760 8cf9ab0a7a512fc822f7dd85bc373e06 359 PANTHER PTHR35145:SF1 16 223 2.6E-32 T 23-04-2016 SPYM18_RS06760 8cf9ab0a7a512fc822f7dd85bc373e06 359 PANTHER PTHR35145 16 223 2.6E-32 T 23-04-2016 SPYM18_RS06760 8cf9ab0a7a512fc822f7dd85bc373e06 359 SUPERFAMILY SSF88697 235 299 9.25E-5 T 23-04-2016 IPR015947 PUA-like domain SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 Gene3D G3DSA:3.40.35.10 169 328 3.0E-64 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 PANTHER PTHR33799 3 330 2.2E-211 T 23-04-2016 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 SUPERFAMILY SSF52728 169 328 3.66E-54 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 SUPERFAMILY SSF53062 2 135 1.31E-35 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 Gene3D G3DSA:3.40.50.510 2 143 3.3E-49 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 Pfam PF03610 PTS system fructose IIA component 4 114 7.1E-34 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 PANTHER PTHR33799:SF7 3 330 2.2E-211 T 23-04-2016 SPYM18_RS07820 e5f16580cd650a5c5b62be31fde8059a 330 Pfam PF03830 PTS system sorbose subfamily IIB component 170 317 6.1E-51 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 SUPERFAMILY SSF53850 4 256 5.44E-60 T 23-04-2016 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 PANTHER PTHR30614:SF15 31 260 5.0E-50 T 23-04-2016 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 257 1.8E-50 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 PANTHER PTHR30614 31 260 5.0E-50 T 23-04-2016 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 SMART SM00079 39 256 0.0086 T 23-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 SMART SM00062 39 261 4.8E-43 T 23-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 Gene3D G3DSA:3.40.190.10 120 214 6.2E-20 T 23-04-2016 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 Gene3D G3DSA:3.40.190.10 36 119 4.2E-34 T 23-04-2016 SPYM18_RS03615 1497aead9209b82193dce1bd83b99aa8 270 Gene3D G3DSA:3.40.190.10 224 258 4.2E-34 T 23-04-2016 SPYM18_RS09175 eca163f0b089f4f71fa723b23e86ed30 208 PANTHER PTHR12234:SF2 1 167 3.7E-56 T 23-04-2016 SPYM18_RS09175 eca163f0b089f4f71fa723b23e86ed30 208 Pfam PF04961 Formiminotransferase-cyclodeaminase 8 185 1.1E-63 T 23-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS09175 eca163f0b089f4f71fa723b23e86ed30 208 PANTHER PTHR12234 1 167 3.7E-56 T 23-04-2016 SPYM18_RS09175 eca163f0b089f4f71fa723b23e86ed30 208 SUPERFAMILY SSF101262 3 206 1.57E-58 T 23-04-2016 IPR007044 Cyclodeaminase/cyclohydrolase GO:0003824|GO:0044237 KEGG: 00340+2.1.2.5|KEGG: 00670+4.3.1.4+2.1.2.5|MetaCyc: PWY-5030|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00379 SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 456 2.3E-159 T 23-04-2016 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26|UniPathway: UPA00238 SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 PANTHER PTHR30175:SF8 21 456 1.5E-154 T 23-04-2016 SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 340 1.8E-86 T 23-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 Gene3D G3DSA:2.115.10.20 43 326 5.7E-17 T 23-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 380 446 4.0E-7 T 23-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 SUPERFAMILY SSF49899 340 469 9.5E-27 T 23-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 PANTHER PTHR30175 21 456 1.5E-154 T 23-04-2016 SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 37 50 - T 23-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 SUPERFAMILY SSF75005 28 341 7.42E-84 T 23-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 Gene3D G3DSA:2.60.120.560 327 467 6.3E-35 T 23-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal SPYM18_RS08115 490165e10ab5ae5925140495192583fb 479 SMART SM00640 37 446 2.0E-126 T 23-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 Gene3D G3DSA:3.40.50.1360 76 212 1.2E-8 T 23-04-2016 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 Pfam PF00455 DeoR C terminal sensor domain 76 232 2.6E-45 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 SUPERFAMILY SSF100950 76 234 2.3E-27 T 23-04-2016 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 SUPERFAMILY SSF46785 5 62 4.05E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 SMART SM00420 6 58 8.9E-23 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 PANTHER PTHR30363:SF10 1 244 5.0E-108 T 23-04-2016 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 PANTHER PTHR30363 1 244 5.0E-108 T 23-04-2016 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 2.5E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 2.5E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 SMART SM01134 74 233 1.1E-58 T 23-04-2016 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 2.6E-20 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS07395 cad18838ed182ef199c8e07215a6a89f 256 Gene3D G3DSA:1.10.10.10 1 51 3.0E-9 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04835 dd61419768edf6d0f8411559a6d8ebbb 216 PANTHER PTHR20855:SF3 14 216 1.2E-49 T 23-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 SPYM18_RS04835 dd61419768edf6d0f8411559a6d8ebbb 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 213 6.9E-59 T 23-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 SPYM18_RS04835 dd61419768edf6d0f8411559a6d8ebbb 216 Pfam PF03006 Haemolysin-III related 12 207 3.5E-29 T 23-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SPYM18_RS04835 dd61419768edf6d0f8411559a6d8ebbb 216 PANTHER PTHR20855 14 216 1.2E-49 T 23-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119:SF9 282 470 1.9E-133 T 23-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119:SF9 202 265 1.9E-133 T 23-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119:SF9 1 173 1.9E-133 T 23-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119 282 470 1.9E-133 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119 202 265 1.9E-133 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PANTHER PTHR11119 1 173 1.9E-133 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 PIRSF PIRSF005353 1 485 8.4E-159 T 23-04-2016 IPR026033 Purine permease PbuG-like SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 Pfam PF00860 Permease family 17 164 8.8E-15 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS07500 8642393264f4addc21414a7ae854bf31 486 Pfam PF00860 Permease family 195 445 9.3E-23 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 PRINTS PR01997 Phage major tail protein 2 family signature 156 175 2.0E-39 T 23-04-2016 IPR022345 Bacteriophage 69, Orf23, major tail protein SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 PRINTS PR01997 Phage major tail protein 2 family signature 56 74 2.0E-39 T 23-04-2016 IPR022345 Bacteriophage 69, Orf23, major tail protein SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 PRINTS PR01997 Phage major tail protein 2 family signature 86 104 2.0E-39 T 23-04-2016 IPR022345 Bacteriophage 69, Orf23, major tail protein SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 PRINTS PR01997 Phage major tail protein 2 family signature 34 56 2.0E-39 T 23-04-2016 IPR022345 Bacteriophage 69, Orf23, major tail protein SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 PRINTS PR01997 Phage major tail protein 2 family signature 132 153 2.0E-39 T 23-04-2016 IPR022345 Bacteriophage 69, Orf23, major tail protein SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 TIGRFAM TIGR02126 phgtail_TP901_1: phage major tail protein, TP901-1 family 12 165 1.3E-21 T 23-04-2016 IPR011855 Phage major tail protein TP901-1 SPYM18_RS05450 1ae8c18f37012ffa66aa1766213090f5 201 Pfam PF06199 Phage tail tube protein 15 110 6.0E-14 T 23-04-2016 IPR011855 Phage major tail protein TP901-1 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 PANTHER PTHR33603 1 159 1.9E-58 T 23-04-2016 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 28.674 T 23-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 PIRSF PIRSF004505 1 159 5.9E-51 T 23-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 Gene3D G3DSA:3.40.1280.10 1 159 5.3E-59 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 8.3E-48 T 23-04-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 PANTHER PTHR33603:SF1 1 159 1.9E-58 T 23-04-2016 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 1.7E-54 T 23-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS09635 69837dfee4a15fe2971c2c78ac55b54d 159 SUPERFAMILY SSF75217 1 157 9.16E-55 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS01095 7f482814e41645700d25ef6f882ba36a 148 SUPERFAMILY SSF51283 12 147 6.41E-37 T 23-04-2016 IPR029054 dUTPase-like SPYM18_RS01095 7f482814e41645700d25ef6f882ba36a 148 Gene3D G3DSA:2.70.40.10 17 147 3.8E-39 T 23-04-2016 IPR029054 dUTPase-like SPYM18_RS01095 7f482814e41645700d25ef6f882ba36a 148 Pfam PF00692 dUTPase 19 146 4.1E-17 T 23-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 SPYM18_RS01095 7f482814e41645700d25ef6f882ba36a 148 PANTHER PTHR11241 19 148 1.6E-29 T 23-04-2016 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Gene3D G3DSA:3.30.30.80 1 51 2.7E-19 T 23-04-2016 IPR032782 Jag, N-terminal SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Pfam PF14804 Jag N-terminus 4 51 1.3E-18 T 23-04-2016 IPR032782 Jag, N-terminal SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Pfam PF01424 R3H domain 242 301 1.0E-14 T 23-04-2016 IPR001374 R3H domain GO:0003676 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 SMART SM00393 224 303 8.8E-14 T 23-04-2016 IPR001374 R3H domain GO:0003676 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 SMART SM01245 3 54 3.1E-19 T 23-04-2016 IPR032782 Jag, N-terminal SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 PANTHER PTHR35800 1 53 8.6E-56 T 23-04-2016 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 PANTHER PTHR35800 153 304 8.6E-56 T 23-04-2016 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Gene3D G3DSA:3.30.300.120 157 233 1.0E-21 T 23-04-2016 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 SUPERFAMILY SSF82708 244 301 1.63E-10 T 23-04-2016 IPR001374 R3H domain GO:0003676 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Pfam PF13083 KH domain 161 230 2.5E-16 T 23-04-2016 SPYM18_RS01145 b40604fa92ef9387015f2ef07e2a89a3 304 Gene3D G3DSA:3.30.1370.50 235 304 5.9E-25 T 23-04-2016 IPR001374 R3H domain GO:0003676 SPYM18_RS02145 6be86d0b7bf3d523422c85e1acc61986 184 SUPERFAMILY SSF55811 6 179 1.62E-43 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS02145 6be86d0b7bf3d523422c85e1acc61986 184 Gene3D G3DSA:3.90.79.10 4 180 6.2E-51 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS02145 6be86d0b7bf3d523422c85e1acc61986 184 PANTHER PTHR11839 6 182 4.7E-55 T 23-04-2016 SPYM18_RS02145 6be86d0b7bf3d523422c85e1acc61986 184 Pfam PF00293 NUDIX domain 42 158 1.8E-12 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 SPYM18_RS02145 6be86d0b7bf3d523422c85e1acc61986 184 PANTHER PTHR11839:SF9 6 182 4.7E-55 T 23-04-2016 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PANTHER PTHR11405 1 274 7.4E-195 T 23-04-2016 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PANTHER PTHR11405 294 334 7.4E-195 T 23-04-2016 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 2.0E-43 T 23-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.5E-23 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 2.5E-23 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 294 317 2.5E-23 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.5E-23 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 Gene3D G3DSA:3.40.50.1370 5 145 2.0E-53 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 329 4.0E-124 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 7.0E-28 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 308 319 7.0E-28 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 7.0E-28 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 228 238 7.0E-28 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 7.0E-28 T 23-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 SUPERFAMILY SSF53671 5 331 1.26E-101 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 327 3.5E-54 T 23-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 Gene3D G3DSA:3.40.50.1370 146 316 9.6E-70 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PANTHER PTHR11405:SF44 1 274 7.4E-195 T 23-04-2016 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 PANTHER PTHR11405:SF44 294 334 7.4E-195 T 23-04-2016 SPYM18_RS06730 8543aaca5e25f7e8eceee1caf851180d 337 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 330 81.051 T 23-04-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 SPYM18_RS01565 08283eb3bee66fe9f98d833e6a2ef472 70 Gene3D G3DSA:1.10.260.40 12 66 7.7E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01565 08283eb3bee66fe9f98d833e6a2ef472 70 SUPERFAMILY SSF47413 3 46 4.41E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01565 08283eb3bee66fe9f98d833e6a2ef472 70 SMART SM00530 11 65 0.0091 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS03715 a3d66ff8e754127fc8fc55ae0ee45e83 158 Gene3D G3DSA:3.10.350.10 113 146 2.0E-4 T 23-04-2016 IPR018392 LysM domain SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 SMART SM00382 26 208 1.6E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 Gene3D G3DSA:3.40.50.300 1 223 6.6E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 PANTHER PTHR24220 3 235 1.7E-86 T 23-04-2016 SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 PANTHER PTHR24220:SF160 3 235 1.7E-86 T 23-04-2016 SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 SUPERFAMILY SSF52540 1 223 1.85E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07250 737e92490ccc9448577a2f6658e4e013 244 Pfam PF00005 ABC transporter 17 160 2.4E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 PANTHER PTHR30346:SF0 1 298 3.0E-75 T 23-04-2016 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 Pfam PF03466 LysR substrate binding domain 129 297 1.8E-10 T 23-04-2016 IPR005119 LysR, substrate-binding SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.3E-16 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 SUPERFAMILY SSF53850 92 297 2.35E-22 T 23-04-2016 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 Gene3D G3DSA:3.40.190.10 174 267 4.3E-6 T 23-04-2016 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 SUPERFAMILY SSF46785 1 82 1.53E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 PANTHER PTHR30346 1 298 3.0E-75 T 23-04-2016 SPYM18_RS04120 0f1dc1935347b5845f8831edb12dd1f1 301 Gene3D G3DSA:1.10.10.10 1 84 2.1E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PIRSF PIRSF000350 63 570 1.7E-78 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 164 174 - T 23-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Gene3D G3DSA:3.50.50.60 128 261 2.6E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 129 581 1.8E-160 T 23-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Gene3D G3DSA:2.40.50.100 1 90 1.4E-27 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Gene3D G3DSA:3.30.390.30 449 581 7.7E-47 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 407 429 5.3E-36 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 151 5.3E-36 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 381 397 5.3E-36 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 276 5.3E-36 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 5.3E-36 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 SUPERFAMILY SSF51230 1 89 2.22E-25 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Gene3D G3DSA:3.50.50.60 262 448 1.1E-51 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PANTHER PTHR22912 116 575 4.4E-178 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Pfam PF00364 Biotin-requiring enzyme 4 76 7.2E-19 T 23-04-2016 IPR000089 Biotin/lipoyl attachment SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 SUPERFAMILY SSF51905 124 450 6.05E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 130 442 2.3E-67 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PANTHER PTHR22912:SF125 116 575 4.4E-178 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 463 571 8.9E-37 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 382 396 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 178 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 429 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 459 480 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 524 539 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 546 566 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 131 153 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 261 270 7.1E-64 T 23-04-2016 SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 23-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site SPYM18_RS04380 63129027483f9c1a60a257545533ce99 587 SUPERFAMILY SSF55424 462 582 7.9E-41 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Gene3D G3DSA:3.30.70.240 405 482 4.9E-34 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PANTHER PTHR23115 189 598 2.6E-290 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PANTHER PTHR23115 1 173 2.6E-290 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 SUPERFAMILY SSF54980 403 518 1.29E-29 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PANTHER PTHR23115:SF14 189 598 2.6E-290 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PANTHER PTHR23115:SF14 1 173 2.6E-290 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 SUPERFAMILY SSF54980 307 392 1.22E-14 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Gene3D G3DSA:2.40.30.10 210 308 9.1E-27 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 603 3.4E-290 T 23-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 2.7E-55 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Pfam PF00679 Elongation factor G C-terminus 401 480 1.1E-24 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 SUPERFAMILY SSF52540 3 212 2.61E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Pfam PF03144 Elongation factor Tu domain 2 224 294 2.1E-13 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Gene3D G3DSA:2.40.50.250 488 582 1.6E-38 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Gene3D G3DSA:3.30.70.870 309 404 2.3E-37 T 23-04-2016 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 SUPERFAMILY SSF50447 155 304 4.57E-32 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 Gene3D G3DSA:3.40.50.300 5 209 4.5E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 SMART SM00838 400 485 1.8E-6 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.8E-14 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.8E-14 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.8E-14 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.8E-14 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.8E-14 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS06650 91c577b3e987a3168dab195be3b4865a 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 146 7.1E-24 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 SUPERFAMILY SSF55826 7 155 1.57E-32 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 Pfam PF04073 Aminoacyl-tRNA editing domain 40 147 1.2E-18 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 PANTHER PTHR30411:SF0 39 158 7.0E-36 T 23-04-2016 SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 PANTHER PTHR30411 39 158 7.0E-36 T 23-04-2016 SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 PIRSF PIRSF006181 5 159 6.9E-48 T 23-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC SPYM18_RS02855 ef4e941addc03e58273a93e001190d1c 159 Gene3D G3DSA:3.90.960.10 3 157 8.0E-40 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 SUPERFAMILY SSF55205 7 420 1.44E-131 T 23-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 PANTHER PTHR21090 2 419 4.1E-244 T 23-04-2016 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 Gene3D G3DSA:3.65.10.10 224 419 3.4E-55 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 PANTHER PTHR21090:SF19 2 419 4.1E-244 T 23-04-2016 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 Gene3D G3DSA:3.65.10.10 22 223 7.4E-64 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 420 43.732 T 23-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 419 5.5E-162 T 23-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS03555 c65eb56379b4764adfb54191c1ad4df5 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 410 5.4E-103 T 23-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 46.22 T 23-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 SUPERFAMILY SSF55681 5 330 3.62E-97 T 23-04-2016 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 PANTHER PTHR30073:SF5 1 330 1.6E-197 T 23-04-2016 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 Pfam PF03590 Aspartate-ammonia ligase 9 243 1.4E-94 T 23-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 PANTHER PTHR30073 1 330 1.6E-197 T 23-04-2016 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 PIRSF PIRSF001555 1 330 9.4E-155 T 23-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 4.4E-180 T 23-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 SPYM18_RS06710 036021b71f99075bc525a7524ddb6204 330 Gene3D G3DSA:3.30.930.10 2 327 2.6E-155 T 23-04-2016 SPYM18_RS04640 95b0281d194707a9d4c99e2d68f790a1 204 PANTHER PTHR30383 32 204 3.1E-14 T 23-04-2016 SPYM18_RS04640 95b0281d194707a9d4c99e2d68f790a1 204 SUPERFAMILY SSF52266 9 204 2.9E-38 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS04640 95b0281d194707a9d4c99e2d68f790a1 204 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 55 193 1.2E-10 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS04640 95b0281d194707a9d4c99e2d68f790a1 204 Gene3D G3DSA:3.40.50.1110 8 204 1.8E-35 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PANTHER PTHR22769 3 149 2.7E-48 T 23-04-2016 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 Pfam PF00293 NUDIX domain 2 130 1.5E-21 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PANTHER PTHR22769:SF39 3 149 2.7E-48 T 23-04-2016 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 Gene3D G3DSA:3.90.79.10 3 154 7.4E-38 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 68 94 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 138 158 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 4 22 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 101 121 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 22 37 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 PRINTS PR01402 Mutator MutX protein signature 121 138 2.4E-55 T 23-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 SPYM18_RS04305 e7735751b267e9adf2cb5ec07f316e5b 158 SUPERFAMILY SSF55811 4 135 6.5E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 23-04-2016 IPR019844 Cold-shock conserved site SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 Gene3D G3DSA:2.40.50.140 1 64 7.7E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 SUPERFAMILY SSF50249 1 65 7.62E-25 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 PIRSF PIRSF002599 1 67 4.4E-25 T 23-04-2016 IPR012156 Cold shock, CspA GO:0003676 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 PANTHER PTHR11544 1 66 1.1E-40 T 23-04-2016 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 SMART SM00357 3 66 8.7E-31 T 23-04-2016 IPR011129 Cold shock protein GO:0003676 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 9.3E-31 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 PRINTS PR00050 Cold shock protein signature 4 19 4.7E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 PRINTS PR00050 Cold shock protein signature 39 57 4.7E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPYM18_RS09140 19ed8939c38df338c89098c0bddad2b9 67 PRINTS PR00050 Cold shock protein signature 24 33 4.7E-19 T 23-04-2016 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 SPYM18_RS03480 40638902ea2b2f645df3409c55551fac 375 PANTHER PTHR30294 1 372 3.4E-43 T 23-04-2016 SPYM18_RS03480 40638902ea2b2f645df3409c55551fac 375 PANTHER PTHR30294:SF23 1 372 3.4E-43 T 23-04-2016 SPYM18_RS03480 40638902ea2b2f645df3409c55551fac 375 Pfam PF12698 ABC-2 family transporter protein 21 366 3.9E-27 T 23-04-2016 SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 PANTHER PTHR24220:SF529 4 192 3.8E-47 T 23-04-2016 SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 Pfam PF00005 ABC transporter 20 151 4.3E-20 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 Gene3D G3DSA:3.40.50.300 3 201 7.6E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 PANTHER PTHR24220 4 192 3.8E-47 T 23-04-2016 SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 SMART SM00382 28 202 7.0E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 SUPERFAMILY SSF52540 3 203 7.33E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08915 e484e30cd7ef1e56178464ddc6b5b49b 208 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01020 b4ebe93572a7988ee009e7ff2046e483 179 PIRSF PIRSF016661 1 178 1.0E-36 T 23-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SPYM18_RS01020 b4ebe93572a7988ee009e7ff2046e483 179 PANTHER PTHR34295:SF2 3 169 1.6E-36 T 23-04-2016 SPYM18_RS01020 b4ebe93572a7988ee009e7ff2046e483 179 PANTHER PTHR34295 3 169 1.6E-36 T 23-04-2016 SPYM18_RS01020 b4ebe93572a7988ee009e7ff2046e483 179 Pfam PF02632 BioY family 30 170 2.9E-30 T 23-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 SPYM18_RS04785 9acc5100a192d911eda67f26000a433f 199 PANTHER PTHR34135:SF3 1 199 4.6E-54 T 23-04-2016 SPYM18_RS04785 9acc5100a192d911eda67f26000a433f 199 SUPERFAMILY SSF53955 32 148 5.06E-10 T 23-04-2016 IPR023346 Lysozyme-like domain SPYM18_RS04785 9acc5100a192d911eda67f26000a433f 199 Pfam PF13702 Lysozyme-like 28 189 1.8E-59 T 23-04-2016 SPYM18_RS04785 9acc5100a192d911eda67f26000a433f 199 PANTHER PTHR34135 1 199 4.6E-54 T 23-04-2016 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 Gene3D G3DSA:3.30.160.100 3 95 3.4E-33 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 SUPERFAMILY SSF69754 4 114 2.09E-31 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 PANTHER PTHR33231 1 182 2.8E-60 T 23-04-2016 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 6.0E-28 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 3 103 2.6E-30 T 23-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 SPYM18_RS07010 bcac809d94a2ddf840fb03e378fe7256 182 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 124 178 5.3E-25 T 23-04-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 Gene3D G3DSA:1.20.120.610 10 157 5.2E-35 T 23-04-2016 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 PANTHER PTHR10263 15 89 6.4E-16 T 23-04-2016 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 106 132 6.2E-10 T 23-04-2016 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 32 56 6.2E-10 T 23-04-2016 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 58 82 6.2E-10 T 23-04-2016 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 133 156 6.2E-10 T 23-04-2016 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 SUPERFAMILY SSF81333 15 81 1.01E-9 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 SUPERFAMILY SSF81333 88 157 1.24E-9 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 Pfam PF00137 ATP synthase subunit C 19 78 3.5E-13 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS00840 9c12daad35f747315ac6320f66fcfb7e 159 Pfam PF00137 ATP synthase subunit C 97 154 5.7E-13 T 23-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 524 651 1.2E-10 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Gene3D G3DSA:1.10.1790.10 298 400 2.5E-20 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Gene3D G3DSA:1.10.1790.10 205 284 1.1E-13 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF08279 HTH domain 6 63 6.0E-13 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 SUPERFAMILY SSF46785 5 65 4.53E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 PANTHER PTHR30185 1 663 4.6E-132 T 23-04-2016 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 SUPERFAMILY SSF55804 516 659 4.53E-15 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Gene3D G3DSA:1.10.10.10 8 66 1.1E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Gene3D G3DSA:3.40.930.10 516 658 8.6E-14 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Gene3D G3DSA:3.40.50.270 407 490 1.8E-8 T 23-04-2016 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 SUPERFAMILY SSF63520 201 283 2.22E-15 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 PANTHER PTHR30185:SF5 1 663 4.6E-132 T 23-04-2016 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF05043 Mga helix-turn-helix domain 69 172 1.8E-28 T 23-04-2016 IPR007737 Mga helix-turn-helix domain SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 408 488 5.0E-9 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 SUPERFAMILY SSF63520 298 400 4.45E-21 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 SUPERFAMILY SSF52794 406 488 9.94E-10 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF00874 PRD domain 208 284 4.5E-13 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS05795 6d35efecafcca92f3d90bcc6ade4f7e6 664 Pfam PF00874 PRD domain 309 396 5.4E-20 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS08330 9c3ab9186eaed1efdb0ad16b18661809 400 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 81 2.7E-18 T 23-04-2016 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 SPYM18_RS08330 9c3ab9186eaed1efdb0ad16b18661809 400 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 196 397 2.2E-58 T 23-04-2016 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: REACT_15518|Reactome: REACT_1698 SPYM18_RS08330 9c3ab9186eaed1efdb0ad16b18661809 400 PANTHER PTHR10590 6 397 4.9E-130 T 23-04-2016 IPR008276 Concentrative nucleoside transporter GO:0005337|GO:0016020|GO:1901642 Reactome: REACT_15518|Reactome: REACT_1698 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 Gene3D G3DSA:3.40.50.300 1 170 2.1E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 Gene3D G3DSA:3.40.50.300 235 360 2.1E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 PANTHER PTHR32182:SF0 1 346 5.0E-65 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 SUPERFAMILY SSF52540 1 361 1.04E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 360 1.8E-16 T 23-04-2016 IPR003395 RecF/RecN/SMC, N-terminal SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 23-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 23-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 368 99.698 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 360 2.8E-140 T 23-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09580 7e901eb6ff1638d44e7655bd0364741f 368 PANTHER PTHR32182 1 346 5.0E-65 T 23-04-2016 SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 PIRSF PIRSF034300 4 133 1.5E-53 T 23-04-2016 IPR014590 Uncharacterised conserved protein MORN repeat-containing SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 SMART SM00698 74 95 0.01 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 SMART SM00698 97 118 2.6 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 SMART SM00698 51 72 70.0 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 Gene3D G3DSA:2.20.110.10 42 130 7.1E-23 T 23-04-2016 SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 SUPERFAMILY SSF82185 45 129 1.12E-20 T 23-04-2016 SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 Pfam PF02493 MORN repeat 53 74 3.1E-4 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 Pfam PF02493 MORN repeat 99 117 0.0021 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 Pfam PF02493 MORN repeat 76 96 3.4E-5 T 23-04-2016 IPR003409 MORN motif SPYM18_RS00340 e0423d9d08faba6450db2bffdab1ea85 133 PANTHER PTHR23084 43 132 3.8E-20 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 SMART SM00642 13 402 6.2E-154 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Pfam PF00128 Alpha amylase, catalytic domain 28 359 1.6E-123 T 23-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357:SF142 440 501 1.5E-229 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357:SF142 1 379 1.5E-229 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357:SF142 395 407 1.5E-229 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Gene3D G3DSA:3.20.20.80 2 103 2.4E-120 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Gene3D G3DSA:3.20.20.80 170 462 2.4E-120 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Pfam PF11941 Domain of unknown function (DUF3459) 448 532 4.9E-5 T 23-04-2016 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 SUPERFAMILY SSF51011 465 535 4.8E-12 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Gene3D G3DSA:2.60.40.1180 468 535 5.2E-14 T 23-04-2016 IPR013780 Glycosyl hydrolase, all-beta SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 Gene3D G3DSA:3.90.400.10 104 166 4.1E-28 T 23-04-2016 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357 440 501 1.5E-229 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357 1 379 1.5E-229 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 PANTHER PTHR10357 395 407 1.5E-229 T 23-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 SPYM18_RS08780 52c173cce49d5e5b62ea9c3c495ed642 537 SUPERFAMILY SSF51445 3 461 5.89E-146 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SMART SM00271 4 61 3.9E-27 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Pfam PF01556 DnaJ C terminal domain 120 337 1.0E-40 T 23-04-2016 IPR002939 Chaperone DnaJ, C-terminal SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 374 39.532 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SUPERFAMILY SSF49493 204 266 2.88E-19 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SUPERFAMILY SSF49493 114 138 2.88E-19 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 23-04-2016 IPR018253 DnaJ domain, conserved site SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Pfam PF00226 DnaJ domain 5 66 9.5E-24 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Pfam PF00684 DnaJ central domain 147 211 2.6E-13 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Gene3D G3DSA:1.10.287.110 1 107 1.4E-36 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PANTHER PTHR24078:SF190 2 359 6.0E-163 T 23-04-2016 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SUPERFAMILY SSF46565 1 104 1.57E-34 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SUPERFAMILY SSF49493 263 348 1.83E-22 T 23-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 SUPERFAMILY SSF57938 134 214 3.79E-19 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PANTHER PTHR24078 2 359 6.0E-163 T 23-04-2016 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Gene3D G3DSA:2.10.230.10 137 209 3.7E-20 T 23-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 354 1.8E-138 T 23-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Gene3D G3DSA:2.60.260.20 261 338 4.0E-21 T 23-04-2016 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Gene3D G3DSA:2.60.260.20 210 257 9.2E-23 T 23-04-2016 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 Gene3D G3DSA:2.60.260.20 111 136 9.2E-23 T 23-04-2016 SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PRINTS PR00625 DnaJ domain signature 25 40 2.5E-30 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PRINTS PR00625 DnaJ domain signature 7 25 2.5E-30 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PRINTS PR00625 DnaJ domain signature 41 61 2.5E-30 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS07910 b39fa5531ac1dbd9969b780ee358e047 378 PRINTS PR00625 DnaJ domain signature 61 80 2.5E-30 T 23-04-2016 IPR001623 DnaJ domain SPYM18_RS06105 4739e993c469afdb7e01cd726c284821 196 SUPERFAMILY SSF56601 2 173 2.6E-21 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS06105 4739e993c469afdb7e01cd726c284821 196 Gene3D G3DSA:3.40.710.10 1 174 2.0E-27 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS06105 4739e993c469afdb7e01cd726c284821 196 Pfam PF13354 Beta-lactamase enzyme family 2 154 1.0E-5 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 Gene3D G3DSA:3.40.50.10170 1 150 6.8E-38 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 280 2.2E-90 T 23-04-2016 IPR003797 DegV SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 PANTHER PTHR33434:SF2 1 281 5.7E-67 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 SUPERFAMILY SSF82549 1 280 4.45E-83 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 Gene3D G3DSA:3.30.1180.10 153 281 2.6E-42 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 PANTHER PTHR33434 1 281 5.7E-67 T 23-04-2016 SPYM18_RS03980 b53bf23effe8b94210369cc9e0ea22a2 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 1.8E-88 T 23-04-2016 IPR003797 DegV SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 SMART SM00382 32 205 2.6E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 PANTHER PTHR24220 9 218 2.6E-76 T 23-04-2016 SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 SUPERFAMILY SSF52540 7 221 5.22E-55 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 Gene3D G3DSA:3.40.50.300 6 224 2.9E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 PANTHER PTHR24220:SF523 9 218 2.6E-76 T 23-04-2016 SPYM18_RS08010 14249ccef4e997279869d64a0644c20a 300 Pfam PF00005 ABC transporter 23 156 9.7E-25 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 PIRSF PIRSF038994 6 382 5.1E-117 T 23-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 PANTHER PTHR11113 34 381 4.4E-140 T 23-04-2016 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 SUPERFAMILY SSF51556 53 350 1.05E-97 T 23-04-2016 IPR032466 Metal-dependent hydrolase SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 SUPERFAMILY SSF51338 350 380 5.28E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 SUPERFAMILY SSF51338 3 52 5.28E-11 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 PANTHER PTHR11113:SF7 34 381 4.4E-140 T 23-04-2016 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 Gene3D G3DSA:2.30.40.10 335 358 1.3E-6 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 Gene3D G3DSA:2.30.40.10 34 54 2.8E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 Gene3D G3DSA:2.30.40.10 359 367 2.8E-7 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 38 376 3.9E-89 T 23-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 Pfam PF01979 Amidohydrolase family 50 372 2.8E-23 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 SPYM18_RS07325 38c81c4aa9a910302bb80450afa83249 382 Gene3D G3DSA:3.20.20.140 55 334 1.8E-97 T 23-04-2016 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 SUPERFAMILY SSF56420 7 201 1.83E-59 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PRINTS PR01576 Peptide deformylase signature 59 88 2.2E-31 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PRINTS PR01576 Peptide deformylase signature 129 140 2.2E-31 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PRINTS PR01576 Peptide deformylase signature 142 160 2.2E-31 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PRINTS PR01576 Peptide deformylase signature 161 190 2.2E-31 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PANTHER PTHR10458 13 204 2.6E-94 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 Gene3D G3DSA:3.90.45.10 15 200 3.1E-54 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 Hamap MF_00163 Peptide deformylase [def]. 15 203 26.801 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 Pfam PF01327 Polypeptide deformylase 16 192 2.2E-46 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PANTHER PTHR10458:SF8 13 204 2.6E-94 T 23-04-2016 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 18 200 3.5E-40 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS08725 11d673790f2dfcc10e45acfda140a993 204 PIRSF PIRSF004749 3 204 5.2E-45 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS03265 aed7abfe0291aa904a1519d9059e62d1 115 Pfam PF05521 Phage head-tail joining protein 7 109 1.4E-18 T 23-04-2016 IPR008767 Bacteriophage SPP1, head-tail adaptor SPYM18_RS03265 aed7abfe0291aa904a1519d9059e62d1 115 TIGRFAM TIGR01563 gp16_SPP1: putative phage head-tail adaptor 5 104 2.1E-7 T 23-04-2016 IPR008767 Bacteriophage SPP1, head-tail adaptor SPYM18_RS09050 6f8c7de30eaf5ce0e77b4da7eb2ca633 102 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 94 3.0E-19 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS09050 6f8c7de30eaf5ce0e77b4da7eb2ca633 102 Gene3D G3DSA:3.40.50.270 1 101 7.0E-35 T 23-04-2016 SPYM18_RS09050 6f8c7de30eaf5ce0e77b4da7eb2ca633 102 PANTHER PTHR34581 2 102 2.1E-35 T 23-04-2016 SPYM18_RS09050 6f8c7de30eaf5ce0e77b4da7eb2ca633 102 PANTHER PTHR34581:SF2 2 102 2.1E-35 T 23-04-2016 SPYM18_RS09050 6f8c7de30eaf5ce0e77b4da7eb2ca633 102 SUPERFAMILY SSF52794 1 101 2.07E-33 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 Gene3D G3DSA:3.40.50.300 1 205 6.3E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 SMART SM00382 26 209 2.4E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 SUPERFAMILY SSF52540 1 207 3.43E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 PANTHER PTHR24220:SF327 3 204 5.5E-84 T 23-04-2016 SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 Pfam PF00005 ABC transporter 18 162 1.1E-32 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05295 9fc9b9f930692ca873fed882206b0744 209 PANTHER PTHR24220 3 204 5.5E-84 T 23-04-2016 SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.5E-37 T 23-04-2016 IPR021131 Ribosomal protein L18e/L15P SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 SUPERFAMILY SSF52080 4 144 3.79E-48 T 23-04-2016 IPR021131 Ribosomal protein L18e/L15P SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 23-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 5.7E-54 T 23-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 PANTHER PTHR12934 1 146 2.6E-76 T 23-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 Gene3D G3DSA:3.100.10.10 32 146 2.1E-40 T 23-04-2016 SPYM18_RS00465 74abd40beb70c5d031ab3d3560ddd578 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 21.864 T 23-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 PANTHER PTHR38435 4 364 8.0E-108 T 23-04-2016 SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 SUPERFAMILY SSF51445 1 239 2.02E-74 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 Gene3D G3DSA:2.40.100.10 245 359 1.1E-36 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 Gene3D G3DSA:3.20.20.70 1 238 1.3E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 Pfam PF05913 Bacterial protein of unknown function (DUF871) 4 359 1.4E-118 T 23-04-2016 IPR008589 Protein of unknown function DUF871, prokaryotic SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 PANTHER PTHR38435:SF1 4 364 8.0E-108 T 23-04-2016 SPYM18_RS05800 5c426709dcb74488f11ed2566eb22215 364 SUPERFAMILY SSF50891 247 360 1.48E-33 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 SUPERFAMILY SSF52540 158 210 5.12E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 SUPERFAMILY SSF52540 1 128 5.12E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PANTHER PTHR23359 1 208 9.6E-82 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PRINTS PR00094 Adenylate kinase signature 32 46 8.1E-31 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PRINTS PR00094 Adenylate kinase signature 82 98 8.1E-31 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PRINTS PR00094 Adenylate kinase signature 173 187 8.1E-31 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PRINTS PR00094 Adenylate kinase signature 4 17 8.1E-31 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 PRINTS PR00094 Adenylate kinase signature 156 171 8.1E-31 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 Pfam PF00406 Adenylate kinase 5 185 6.6E-56 T 23-04-2016 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 TIGRFAM TIGR01351 adk: adenylate kinase 2 208 1.5E-73 T 23-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 Gene3D G3DSA:3.40.50.300 1 207 1.1E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00475 d6be16abe9002c705182386a16bbb504 212 Hamap MF_00235 Adenylate kinase [adk]. 1 209 48.294 T 23-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Gene3D G3DSA:3.40.120.10 230 306 8.4E-21 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 PANTHER PTHR22573:SF54 19 564 9.7E-200 T 23-04-2016 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 247 4.4E-7 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 295 310 4.4E-7 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 139 153 4.4E-7 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 211 310 1.6E-19 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Gene3D G3DSA:3.30.310.50 479 560 2.1E-22 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 SUPERFAMILY SSF55957 468 542 2.75E-12 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Gene3D G3DSA:3.40.120.10 307 453 1.0E-33 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 42 183 3.3E-43 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Gene3D G3DSA:3.40.120.10 25 215 1.2E-60 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 140 149 - T 23-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 SUPERFAMILY SSF53738 303 453 6.67E-30 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 PANTHER PTHR22573 19 564 9.7E-200 T 23-04-2016 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 443 1.8E-19 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 SUPERFAMILY SSF53738 31 235 3.69E-46 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 496 535 5.3E-8 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS06550 657d16be1687196464bee9531c3370f8 564 SUPERFAMILY SSF53738 221 311 1.37E-19 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS08880 ff1191a7d5727c964fe52ce98a537eff 168 Pfam PF00005 ABC transporter 2 32 4.4E-5 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08880 ff1191a7d5727c964fe52ce98a537eff 168 Gene3D G3DSA:3.40.50.300 2 156 2.2E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08880 ff1191a7d5727c964fe52ce98a537eff 168 PANTHER PTHR37816 1 164 1.0E-34 T 23-04-2016 SPYM18_RS08880 ff1191a7d5727c964fe52ce98a537eff 168 PANTHER PTHR37816:SF1 1 164 1.0E-34 T 23-04-2016 SPYM18_RS08880 ff1191a7d5727c964fe52ce98a537eff 168 SUPERFAMILY SSF52540 2 99 9.77E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 2.5E-27 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 SUPERFAMILY SSF46557 4 78 1.83E-25 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 PIRSF PIRSF006092 1 160 1.5E-45 T 23-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 Gene3D G3DSA:1.10.287.180 4 77 2.9E-30 T 23-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 23-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 SUPERFAMILY SSF54534 83 157 1.12E-17 T 23-04-2016 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 31.138 T 23-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 23-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 Gene3D G3DSA:3.10.50.30 78 157 1.8E-25 T 23-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 PANTHER PTHR30437 1 157 1.6E-55 T 23-04-2016 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 157 1.6E-54 T 23-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 SPYM18_RS01840 611669e903dbeb72524280b2579ee356 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 9.7E-24 T 23-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 11 108 1.8E-30 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 PANTHER PTHR30614 1 214 1.5E-78 T 23-04-2016 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 SUPERFAMILY SSF161098 13 204 4.84E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 PANTHER PTHR30614:SF18 1 214 1.5E-78 T 23-04-2016 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 213 4.8E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04150 69a6b8056b47e1feb1e41bb8446858c1 216 Gene3D G3DSA:1.10.3720.10 14 213 1.5E-46 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 Pfam PF01351 Ribonuclease HII 307 347 1.1E-4 T 23-04-2016 IPR024567 Ribonuclease HII/HIII domain SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PANTHER PTHR21581:SF11 197 318 2.4E-50 T 23-04-2016 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PANTHER PTHR21581:SF11 44 181 2.4E-50 T 23-04-2016 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PANTHER PTHR21581 197 318 2.4E-50 T 23-04-2016 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PANTHER PTHR21581 44 181 2.4E-50 T 23-04-2016 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 Gene3D G3DSA:3.40.710.10 9 315 6.3E-70 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 43 290 7.0E-44 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 126 143 1.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 154 167 1.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 69 80 1.0E-10 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS01330 299b2b55cb1edc11d3343e0438a4eba7 393 SUPERFAMILY SSF56601 4 315 1.03E-61 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 PANTHER PTHR24031 160 275 2.0E-22 T 23-04-2016 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 PANTHER PTHR24031 1 109 2.0E-22 T 23-04-2016 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 Pfam PF00271 Helicase conserved C-terminal domain 182 283 6.8E-14 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 PANTHER PTHR24031:SF210 160 275 2.0E-22 T 23-04-2016 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 SUPERFAMILY SSF52540 26 296 3.48E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 Gene3D G3DSA:3.40.50.300 2 111 2.2E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 PANTHER PTHR24031:SF210 1 109 2.0E-22 T 23-04-2016 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 Pfam PF04851 Type III restriction enzyme, res subunit 2 51 8.9E-7 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 Pfam PF04851 Type III restriction enzyme, res subunit 67 109 9.6E-7 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 Gene3D G3DSA:3.40.50.300 179 293 2.4E-22 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05600 efbfb735121758a3ccdc82d915a52639 455 SMART SM00490 203 284 6.1E-14 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 PANTHER PTHR10000 1 271 3.4E-75 T 23-04-2016 SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 SUPERFAMILY SSF56784 1 270 2.88E-69 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 Gene3D G3DSA:3.30.1240.10 86 183 1.0E-18 T 23-04-2016 SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 3.6E-27 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 264 3.0E-60 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 PANTHER PTHR10000:SF1 1 271 3.4E-75 T 23-04-2016 SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 Gene3D G3DSA:3.40.50.1000 1 76 9.0E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 Gene3D G3DSA:3.40.50.1000 184 271 9.0E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 264 7.1E-55 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS02735 e84d06e13577515ccb448f768b66fc72 274 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 574 586 - T 23-04-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PANTHER PTHR30523:SF0 362 920 0.0 T 23-04-2016 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PANTHER PTHR30523:SF0 3 346 0.0 T 23-04-2016 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PANTHER PTHR30523 3 346 0.0 T 23-04-2016 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 572 592 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 749 775 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 243 258 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 410 430 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 614 643 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 4.5E-51 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 SUPERFAMILY SSF51621 17 920 5.02E-281 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 920 4.7E-252 T 23-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 920 17.442 T 23-04-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 PANTHER PTHR30523 362 920 0.0 T 23-04-2016 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 23-04-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 SPYM18_RS02890 da67be1f11798f2d482974aef8a43207 920 Gene3D G3DSA:1.20.1440.90 272 413 8.3E-26 T 23-04-2016 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 SUPERFAMILY SSF53041 3 152 6.15E-39 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 SMART SM00857 4 153 1.7E-57 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 PANTHER PTHR30461 3 468 1.1E-67 T 23-04-2016 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 Gene3D G3DSA:3.40.50.1390 3 136 2.0E-34 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 PANTHER PTHR30461:SF3 3 468 1.1E-67 T 23-04-2016 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 Pfam PF07508 Recombinase 178 257 3.5E-12 T 23-04-2016 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 Pfam PF00239 Resolvase, N terminal domain 4 152 6.0E-43 T 23-04-2016 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 SPYM18_RS03065 59a14585c2c70ca2eb93f418a57eccb5 471 Pfam PF13408 Recombinase zinc beta ribbon domain 274 346 1.2E-6 T 23-04-2016 IPR025827 Recombinase zinc beta ribbon domain SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 SUPERFAMILY SSF46894 138 209 9.18E-24 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 PANTHER PTHR26402 4 204 1.5E-78 T 23-04-2016 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 Gene3D G3DSA:3.40.50.2300 2 120 1.8E-30 T 23-04-2016 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 Pfam PF00072 Response regulator receiver domain 6 118 2.4E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 Gene3D G3DSA:1.10.10.10 121 210 7.9E-33 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 SMART SM00448 4 117 7.9E-25 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 SUPERFAMILY SSF52172 3 128 4.84E-29 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 PANTHER PTHR26402:SF151 4 204 1.5E-78 T 23-04-2016 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 202 7.9E-21 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 SMART SM00421 145 202 2.4E-25 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 8.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 8.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS07045 5fb383557ce0f4f83138da74ae96e60e 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 8.3E-14 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 Pfam PF00557 Metallopeptidase family M24 139 341 7.3E-60 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 23-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 PANTHER PTHR10804 6 356 2.3E-91 T 23-04-2016 SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 SUPERFAMILY SSF53092 6 130 4.01E-24 T 23-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 131 1.3E-25 T 23-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 SUPERFAMILY SSF55920 130 357 9.55E-72 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 Gene3D G3DSA:3.40.350.10 5 129 1.7E-27 T 23-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 PANTHER PTHR10804:SF86 6 356 2.3E-91 T 23-04-2016 SPYM18_RS08145 8465b2931d1f96cb3029b3d83059f25a 357 Gene3D G3DSA:3.90.230.10 131 355 2.5E-80 T 23-04-2016 IPR000994 Peptidase M24, structural domain SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 SUPERFAMILY SSF100950 244 509 8.98E-59 T 23-04-2016 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 TIGRFAM TIGR01584 citF: citrate lyase, alpha subunit 31 510 6.6E-240 T 23-04-2016 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 SUPERFAMILY SSF100950 5 240 6.7E-75 T 23-04-2016 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 PIRSF PIRSF009451 1 510 7.6E-265 T 23-04-2016 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 Gene3D G3DSA:3.40.1080.10 2 241 1.7E-108 T 23-04-2016 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 PANTHER PTHR40596 2 510 3.0E-240 T 23-04-2016 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 Gene3D G3DSA:3.40.810.20 244 484 5.2E-77 T 23-04-2016 SPYM18_RS04935 1f4f5b33bf803ff05f2bfe84f5245a13 510 Pfam PF04223 Citrate lyase, alpha subunit (CitF) 45 510 1.1E-264 T 23-04-2016 IPR006472 Citrate lyase, alpha subunit GO:0005737|GO:0006084|GO:0008814|GO:0009346 MetaCyc: PWY-6038 SPYM18_RS07740 6501ff6e1f53b17a6c3feb87568123d7 160 Pfam PF05565 Siphovirus Gp157 5 160 3.0E-39 T 23-04-2016 IPR008840 Siphovirus Gp157 SPYM18_RS01000 f6f2d7812f84293e6a4db2e59f3ac50e 155 PANTHER PTHR33202 14 152 1.2E-39 T 23-04-2016 SPYM18_RS01000 f6f2d7812f84293e6a4db2e59f3ac50e 155 PANTHER PTHR33202:SF7 14 152 1.2E-39 T 23-04-2016 SPYM18_RS01000 f6f2d7812f84293e6a4db2e59f3ac50e 155 SUPERFAMILY SSF46785 14 146 4.58E-37 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01000 f6f2d7812f84293e6a4db2e59f3ac50e 155 Pfam PF01475 Ferric uptake regulator family 22 141 8.2E-37 T 23-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 SPYM18_RS01000 f6f2d7812f84293e6a4db2e59f3ac50e 155 Gene3D G3DSA:1.10.10.10 14 91 7.2E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 SUPERFAMILY SSF46785 1 112 2.02E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 Gene3D G3DSA:1.10.10.10 1 83 1.4E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.9E-12 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 PANTHER PTHR30419:SF8 1 290 3.1E-57 T 23-04-2016 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 Gene3D G3DSA:3.40.190.10 199 268 6.9E-7 T 23-04-2016 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 Gene3D G3DSA:3.40.190.10 92 198 5.8E-12 T 23-04-2016 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 PANTHER PTHR30419 1 290 3.1E-57 T 23-04-2016 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 SUPERFAMILY SSF53850 90 291 2.17E-18 T 23-04-2016 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 Pfam PF03466 LysR substrate binding domain 92 282 9.3E-19 T 23-04-2016 IPR005119 LysR, substrate-binding SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS00795 99e0f9ddd522c7fcf8a003ae287a19fb 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.6E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS09520 201ad5104634ea0c51a43a17abd06370 204 SUPERFAMILY SSF53955 133 189 4.74E-11 T 23-04-2016 IPR023346 Lysozyme-like domain SPYM18_RS09520 201ad5104634ea0c51a43a17abd06370 204 Gene3D G3DSA:1.10.530.10 134 180 3.9E-9 T 23-04-2016 SPYM18_RS09520 201ad5104634ea0c51a43a17abd06370 204 Pfam PF01464 Transglycosylase SLT domain 134 176 5.7E-7 T 23-04-2016 IPR008258 Transglycosylase SLT domain 1 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 PANTHER PTHR11014 4 94 9.8E-165 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 PANTHER PTHR11014 134 404 9.8E-165 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 SUPERFAMILY SSF53187 325 404 5.78E-73 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 SUPERFAMILY SSF53187 3 213 5.78E-73 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 TIGRFAM TIGR01882 peptidase-T: peptidase T 2 404 2.2E-191 T 23-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 PIRSF PIRSF037215 1 407 1.9E-180 T 23-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 SUPERFAMILY SSF55031 212 323 9.77E-40 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Gene3D G3DSA:3.40.630.10 1 212 2.0E-111 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Gene3D G3DSA:3.40.630.10 325 405 2.0E-111 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Hamap MF_00550 Peptidase T [pepT]. 3 407 55.977 T 23-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Pfam PF07687 Peptidase dimerisation domain 210 304 2.0E-10 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 141 180 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 PANTHER PTHR11014:SF3 4 94 9.8E-165 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 PANTHER PTHR11014:SF3 134 404 9.8E-165 T 23-04-2016 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Pfam PF01546 Peptidase family M20/M25/M40 142 404 2.0E-11 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPYM18_RS03705 8c6173a41fc57e68cd2c9a34276ea37f 407 Gene3D G3DSA:3.30.70.360 213 322 2.5E-44 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Hamap MF_01263 CCA-adding enzyme [cca]. 7 400 42.878 T 23-04-2016 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 250 396 8.4E-47 T 23-04-2016 IPR032810 CCA-adding enzyme, C-terminal SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 SUPERFAMILY SSF81891 145 398 2.09E-55 T 23-04-2016 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 SUPERFAMILY SSF81301 10 144 2.07E-41 T 23-04-2016 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 233 1.8E-18 T 23-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Gene3D G3DSA:1.10.3090.10 148 367 7.1E-52 T 23-04-2016 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Gene3D G3DSA:3.30.460.10 11 147 1.4E-46 T 23-04-2016 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 Pfam PF01743 Poly A polymerase head domain 27 147 6.1E-36 T 23-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 SPYM18_RS03985 df3cadc1cd11b5c47cb0b5c38b67a488 402 PANTHER PTHR13734 12 246 9.7E-73 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 ProSitePatterns PS01233 Urocanase signature. 540 555 - T 23-04-2016 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 PANTHER PTHR12216:SF3 7 674 0.0 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 PIRSF PIRSF001423 78 663 3.5E-178 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 Gene3D G3DSA:3.40.50.10730 220 442 1.8E-83 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 SUPERFAMILY SSF111326 82 652 9.29E-226 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 TIGRFAM TIGR01228 hutU: urocanate hydratase 104 645 2.8E-128 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 Hamap MF_00577 Urocanate hydratase [hutU]. 61 660 43.98 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 Gene3D G3DSA:3.40.1770.10 454 647 1.9E-144 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 Gene3D G3DSA:3.40.1770.10 85 219 1.9E-144 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 PANTHER PTHR12216 7 674 0.0 T 23-04-2016 SPYM18_RS09165 bb5515dc08b7ac974c1160bcb2ba59e0 676 Pfam PF01175 Urocanase 91 643 3.3E-233 T 23-04-2016 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 9 311 1.2E-69 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 SMART SM01240 6 327 3.7E-109 T 23-04-2016 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 Gene3D G3DSA:3.20.20.70 7 320 1.6E-85 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 Hamap MF_01511 GMP reductase [guaC]. 5 326 61.675 T 23-04-2016 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 166 178 - T 23-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 SUPERFAMILY SSF51412 7 316 2.35E-91 T 23-04-2016 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 PIRSF PIRSF036500 3 327 1.0E-190 T 23-04-2016 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 PANTHER PTHR11911:SF97 171 316 3.0E-149 T 23-04-2016 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 PANTHER PTHR11911:SF97 10 153 3.0E-149 T 23-04-2016 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 TIGRFAM TIGR01306 GMP_reduct_2: guanosine monophosphate reductase 7 325 1.2E-204 T 23-04-2016 IPR005994 Guanosine monophosphate reductase, type2 GO:0003920|GO:0006163|GO:1902560 KEGG: 00230+1.7.1.7 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 PANTHER PTHR11911 171 316 3.0E-149 T 23-04-2016 SPYM18_RS04725 cd7bbfeedf3def7ec5f9e08e7e6e84c6 327 PANTHER PTHR11911 10 153 3.0E-149 T 23-04-2016 SPYM18_RS02245 faf376cb9123a82b47481bf98f783157 350 SUPERFAMILY SSF52540 112 292 1.46E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02245 faf376cb9123a82b47481bf98f783157 350 Gene3D G3DSA:3.40.50.300 111 315 2.2E-87 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02245 faf376cb9123a82b47481bf98f783157 350 PANTHER PTHR30473 6 338 9.5E-162 T 23-04-2016 SPYM18_RS02245 faf376cb9123a82b47481bf98f783157 350 Pfam PF02562 PhoH-like protein 112 315 1.7E-94 T 23-04-2016 IPR003714 PhoH-like protein GO:0005524 SPYM18_RS02245 faf376cb9123a82b47481bf98f783157 350 PANTHER PTHR30473:SF1 6 338 9.5E-162 T 23-04-2016 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 TIGRFAM TIGR02113 coaC_strep: phosphopantothenoylcysteine decarboxylase 3 178 5.5E-102 T 23-04-2016 IPR011847 Phosphopantothenoylcysteine decarboxylase KEGG: 00770+4.1.1.36|UniPathway: UPA00241 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 Gene3D G3DSA:3.40.50.1950 3 177 5.8E-60 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 PANTHER PTHR14359 3 179 1.9E-66 T 23-04-2016 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 SUPERFAMILY SSF52507 2 176 2.62E-57 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 PANTHER PTHR14359:SF20 3 179 1.9E-66 T 23-04-2016 SPYM18_RS05075 d9359358cd7dda403b617dd28fb5dbdb 181 Pfam PF02441 Flavoprotein 3 133 1.4E-37 T 23-04-2016 IPR003382 Flavoprotein GO:0003824 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PANTHER PTHR22912 5 450 8.0E-239 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PIRSF PIRSF000350 3 446 1.0E-76 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 1.9E-63 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Gene3D G3DSA:3.30.390.30 330 450 1.4E-42 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 23-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Gene3D G3DSA:3.50.50.60 249 329 8.8E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Gene3D G3DSA:3.50.50.60 5 148 1.8E-42 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Gene3D G3DSA:3.50.50.60 149 248 1.4E-29 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 SUPERFAMILY SSF51905 4 362 1.19E-55 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 9.7E-29 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 9.7E-29 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 9.7E-29 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 9.7E-29 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 9.7E-29 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.6E-65 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 5 450 1.3E-213 T 23-04-2016 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 PANTHER PTHR22912:SF106 5 450 8.0E-239 T 23-04-2016 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 2.8E-34 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS03765 bc582c261461adc5c57f2e425c6bce58 450 SUPERFAMILY SSF55424 336 450 5.5E-35 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPYM18_RS00590 366dc95a61163d30d766f8d124e2e9fe 82 PANTHER PTHR20861:SF2 3 82 2.4E-22 T 23-04-2016 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560|UniPathway: UPA00056 SPYM18_RS00590 366dc95a61163d30d766f8d124e2e9fe 82 Gene3D G3DSA:3.30.230.10 2 61 7.6E-16 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS00590 366dc95a61163d30d766f8d124e2e9fe 82 SUPERFAMILY SSF54211 2 62 2.96E-13 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS00590 366dc95a61163d30d766f8d124e2e9fe 82 PANTHER PTHR20861 3 82 2.4E-22 T 23-04-2016 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 Gene3D G3DSA:1.10.1790.10 283 382 1.3E-21 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 531 676 7.1E-33 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 PANTHER PTHR36203 1 682 6.4E-93 T 23-04-2016 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 577 593 - T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 SUPERFAMILY SSF52794 396 462 1.99E-5 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 Pfam PF00874 PRD domain 291 380 3.9E-21 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 SUPERFAMILY SSF55804 528 676 2.35E-35 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 SUPERFAMILY SSF63520 284 383 1.7E-23 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS08705 fdf5148b7f69efac1cb09cef86e8dfe3 686 Gene3D G3DSA:3.40.930.10 528 680 1.5E-52 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 Gene3D G3DSA:3.40.50.10750 138 299 5.6E-68 T 23-04-2016 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 PANTHER PTHR23406 1 330 2.9E-44 T 23-04-2016 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 PANTHER PTHR23406:SF3 1 330 2.9E-44 T 23-04-2016 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 PIRSF PIRSF000428 1 330 5.0E-107 T 23-04-2016 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 21 323 4.7E-118 T 23-04-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 SUPERFAMILY SSF53659 7 326 6.17E-96 T 23-04-2016 SPYM18_RS04700 4fcb48f5358c592b3fa598215a4573a3 331 Pfam PF01515 Phosphate acetyl/butaryl transferase 11 323 1.1E-117 T 23-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 Gene3D G3DSA:1.10.286.10 3 52 2.0E-23 T 23-04-2016 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 PANTHER PTHR11109 3 184 4.3E-101 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 Gene3D G3DSA:3.30.1130.10 57 186 5.7E-59 T 23-04-2016 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 Pfam PF01227 GTP cyclohydrolase I 9 185 1.1E-76 T 23-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 10 186 7.7E-73 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 4 186 41.705 T 23-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 64 80 - T 23-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 113 123 - T 23-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 SPYM18_RS04560 cd8edd13c7acc82d2fdbfd1446497646 188 SUPERFAMILY SSF55620 4 185 1.93E-73 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 TIGRFAM TIGR01078 arcA: arginine deiminase 7 411 3.9E-189 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 Gene3D G3DSA:3.75.10.10 158 411 1.2E-128 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 Gene3D G3DSA:3.75.10.10 4 70 1.2E-128 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737:SF13 315 411 1.4E-115 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737:SF13 4 94 1.4E-115 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737:SF13 157 296 1.4E-115 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 Gene3D G3DSA:1.10.3930.10 71 157 1.9E-31 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 Pfam PF02274 Amidinotransferase 21 408 1.2E-98 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 185 200 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 157 175 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 367 381 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 347 364 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 5 25 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PRINTS PR01466 Bacterial arginine deiminase signature 390 408 3.12E-59 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737 315 411 1.4E-115 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737 4 94 1.4E-115 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PANTHER PTHR12737 157 296 1.4E-115 T 23-04-2016 IPR033199 Dimethylarginine dimethylaminohydrolase/arginine deiminase KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 PIRSF PIRSF006356 1 411 7.6E-171 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 SUPERFAMILY SSF55909 5 411 1.35E-132 T 23-04-2016 SPYM18_RS06740 1aa3a878545f43ad841335784d8fa9c3 411 Hamap MF_00242 Arginine deiminase [arcA]. 4 411 46.921 T 23-04-2016 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981|UniPathway: UPA00254 SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.713 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 Gene3D G3DSA:2.40.50.140 1 139 5.7E-51 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 Pfam PF00436 Single-strand binding protein family 2 103 3.0E-35 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 SUPERFAMILY SSF50249 1 139 6.85E-53 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 PANTHER PTHR10302 1 139 5.0E-38 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 PIRSF PIRSF002070 1 136 9.8E-38 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS07730 094695b8d2030cad04425a3229ed8ef7 139 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 125 6.8E-41 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 SUPERFAMILY SSF63562 2 78 2.27E-22 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 SMART SM01409 9 61 6.9E-11 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 59 5.3E-13 T 23-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 PANTHER PTHR34476 3 91 8.4E-20 T 23-04-2016 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 62 14.194 T 23-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 Pfam PF01192 RNA polymerase Rpb6 10 59 1.3E-9 T 23-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS07085 162f3c71f480ab8ddd049f0d17f5289d 105 Gene3D G3DSA:3.90.940.10 2 84 2.0E-24 T 23-04-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 146 152 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 SUPERFAMILY SSF53335 42 226 9.65E-29 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 PANTHER PTHR18895 10 268 7.4E-91 T 23-04-2016 SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 Pfam PF05175 Methyltransferase small domain 50 200 7.6E-12 T 23-04-2016 IPR007848 Methyltransferase small domain GO:0008168 SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 Gene3D G3DSA:3.40.50.150 60 271 1.4E-68 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06140 bad4fdc462a0274952053602fce05d57 284 PANTHER PTHR18895:SF75 10 268 7.4E-91 T 23-04-2016 SPYM18_RS05850 f3c33c2664b8d8d2cdd39325de08251b 189 SUPERFAMILY SSF53098 107 188 6.45E-15 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS05850 f3c33c2664b8d8d2cdd39325de08251b 189 Gene3D G3DSA:3.30.420.10 108 188 5.9E-12 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS05850 f3c33c2664b8d8d2cdd39325de08251b 189 Pfam PF13276 HTH-like domain 32 83 4.1E-17 T 23-04-2016 IPR025948 HTH-like domain SPYM18_RS05850 f3c33c2664b8d8d2cdd39325de08251b 189 PANTHER PTHR32552 6 188 5.7E-35 T 23-04-2016 SPYM18_RS05850 f3c33c2664b8d8d2cdd39325de08251b 189 Pfam PF00665 Integrase core domain 113 188 2.3E-14 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 SUPERFAMILY SSF74982 4 132 1.57E-49 T 23-04-2016 IPR023620 Small protein B SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 23-04-2016 IPR020081 SsrA-binding protein, conserved site SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 PANTHER PTHR30308:SF2 1 155 2.6E-75 T 23-04-2016 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 PANTHER PTHR30308 1 155 2.6E-75 T 23-04-2016 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 Hamap MF_00023 SsrA-binding protein [smpB]. 1 155 69.626 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 Pfam PF01668 SmpB protein 8 72 6.2E-30 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 132 1.0E-66 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 Gene3D G3DSA:2.40.280.10 8 127 2.6E-50 T 23-04-2016 IPR023620 Small protein B SPYM18_RS02430 6032d93e46d7c5da75ac344159fb80e2 155 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 7.7E-56 T 23-04-2016 IPR000037 SsrA-binding protein GO:0003723 SPYM18_RS00640 3d1cf592567bc0c8fc4ba493776708b1 121 Pfam PF06279 Protein of unknown function (DUF1033) 1 117 2.4E-51 T 23-04-2016 IPR010434 Protein of unknown function DUF1033 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 SUPERFAMILY SSF52540 344 591 9.63E-85 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 PANTHER PTHR24221:SF266 65 591 1.2E-246 T 23-04-2016 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 PANTHER PTHR24221:SF266 1 48 1.2E-246 T 23-04-2016 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 Gene3D G3DSA:1.20.1560.10 7 338 8.2E-64 T 23-04-2016 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 Pfam PF00664 ABC transporter transmembrane region 20 309 3.2E-40 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 Pfam PF00005 ABC transporter 371 520 4.5E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 Gene3D G3DSA:3.40.50.300 354 584 1.1E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 PANTHER PTHR24221 65 591 1.2E-246 T 23-04-2016 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 PANTHER PTHR24221 1 48 1.2E-246 T 23-04-2016 SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 SMART SM00382 380 566 7.2E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01085 591f308bc1b77b228b37fb74d0152a3d 594 SUPERFAMILY SSF90123 5 342 1.29E-59 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 SUPERFAMILY SSF51569 1 217 1.78E-59 T 23-04-2016 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 PANTHER PTHR10683:SF11 1 216 1.4E-85 T 23-04-2016 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 Pfam PF00923 Transaldolase 4 208 7.6E-42 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 ProSitePatterns PS00958 Transaldolase active site. 84 101 - T 23-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 PANTHER PTHR10683 1 216 1.4E-85 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS09035 d951f74d16e3fd95ea9b4d5c27438eb9 222 Gene3D G3DSA:3.20.20.70 1 216 8.5E-54 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 11 211 1.3E-87 T 23-04-2016 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 50 58 - T 23-04-2016 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 Gene3D G3DSA:3.40.810.20 11 214 1.5E-81 T 23-04-2016 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 SUPERFAMILY SSF100950 10 213 2.05E-64 T 23-04-2016 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 SMART SM00882 12 205 1.4E-61 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 Pfam PF01144 Coenzyme A transferase 13 204 5.9E-32 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS00810 c2164fe4e4b62af7ab6e45969f460cf3 215 PANTHER PTHR13707 13 213 1.3E-100 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 Gene3D G3DSA:3.40.50.300 1 235 3.7E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 SUPERFAMILY SSF52540 1 237 1.11E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 Pfam PF00005 ABC transporter 18 163 7.3E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 PANTHER PTHR24220 3 241 1.7E-125 T 23-04-2016 SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 PANTHER PTHR24220:SF434 3 241 1.7E-125 T 23-04-2016 SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04715 816d4c9d589ad2db5c56708e327ae5e0 242 SMART SM00382 26 221 6.5E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 PANTHER PTHR37307 2 303 1.3E-102 T 23-04-2016 SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 301 4.2E-104 T 23-04-2016 SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 Pfam PF02650 WhiA C-terminal HTH domain 217 300 1.0E-29 T 23-04-2016 IPR023054 Sporulation regulator WhiA, C-terminal SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 Pfam PF14527 WhiA LAGLIDADG-like domain 122 214 3.8E-28 T 23-04-2016 SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 SUPERFAMILY SSF55608 117 218 2.98E-13 T 23-04-2016 IPR027434 Homing endonuclease GO:0004519 SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 99 8.3E-27 T 23-04-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 Gene3D G3DSA:3.10.28.10 117 209 2.9E-6 T 23-04-2016 IPR027434 Homing endonuclease GO:0004519 SPYM18_RS03060 2d28d3493fde3ca1bf070fe885b803b2 303 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 303 28.838 T 23-04-2016 IPR003802 Sporulation regulator WhiA GO:0043937 SPYM18_RS07560 c28757b2b41a69f0b818efd542faab15 369 Pfam PF07212 Hyaluronidase protein (HylP) 91 369 2.0E-143 T 23-04-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 SPYM18_RS07560 c28757b2b41a69f0b818efd542faab15 369 SUPERFAMILY SSF69349 8 367 9.42E-119 T 23-04-2016 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 SMART SM00882 6 217 3.5E-74 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 23-04-2016 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 Pfam PF01144 Coenzyme A transferase 8 216 5.3E-67 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 8 216 4.3E-68 T 23-04-2016 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 SUPERFAMILY SSF100950 3 216 1.01E-77 T 23-04-2016 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 PANTHER PTHR13707 1 216 2.7E-91 T 23-04-2016 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 SPYM18_RS00805 b985c2396a8cc6ca4d220f3a8295b604 219 Gene3D G3DSA:3.40.1080.10 5 216 2.2E-84 T 23-04-2016 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 207 223 - T 23-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 274 4.6E-81 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 234 245 - T 23-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 272 1.7E-55 T 23-04-2016 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 252 3.4E-25 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 37 46 - T 23-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 PANTHER PTHR22748 1 275 7.0E-85 T 23-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 Gene3D G3DSA:3.60.10.10 1 274 8.1E-77 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS02060 5466fd16d2335f3cb4394817287d959f 275 SUPERFAMILY SSF56219 1 275 4.45E-60 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 SUPERFAMILY SSF53067 4 291 2.55E-41 T 23-04-2016 SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 PANTHER PTHR18964 1 292 1.3E-77 T 23-04-2016 SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 ProSitePatterns PS01125 ROK family signature. 131 156 - T 23-04-2016 IPR000600 ROK family SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 Gene3D G3DSA:3.30.420.40 108 291 6.4E-59 T 23-04-2016 SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 PANTHER PTHR18964:SF10 1 292 1.3E-77 T 23-04-2016 SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 Gene3D G3DSA:3.30.420.40 2 107 5.6E-38 T 23-04-2016 SPYM18_RS08100 191edf975e2e54c0464b483585b53950 294 Pfam PF00480 ROK family 5 288 1.5E-74 T 23-04-2016 IPR000600 ROK family SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 295 3.2E-30 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 Gene3D G3DSA:3.50.50.60 3 126 2.7E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 Gene3D G3DSA:3.50.50.60 248 326 2.7E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 6.8E-20 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 6.8E-20 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.8E-20 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 6.8E-20 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 6.8E-20 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PANTHER PTHR22912:SF158 2 319 5.6E-119 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 Gene3D G3DSA:3.50.50.60 128 247 2.6E-18 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 SUPERFAMILY SSF51905 4 313 1.84E-38 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 Hamap MF_01685 Ferredoxin--NADP reductase. 5 328 40.445 T 23-04-2016 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PANTHER PTHR22912 2 319 5.6E-119 T 23-04-2016 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 7.9E-23 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 275 293 7.9E-23 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 151 175 7.9E-23 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 64 74 7.9E-23 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS03915 47f95822dafa5876f56e65be9aec4c7f 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 7.9E-23 T 23-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 Gene3D G3DSA:2.60.220.10 741 796 2.8E-7 T 23-04-2016 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 77 422 1.0E-129 T 23-04-2016 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 Gene3D G3DSA:2.70.98.10 467 739 1.0E-85 T 23-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 SUPERFAMILY SSF48230 68 457 6.72E-114 T 23-04-2016 IPR008929 Chondroitin AC/alginate lyase SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 SUPERFAMILY SSF74650 462 757 1.83E-94 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 466 737 3.3E-66 T 23-04-2016 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 Gene3D G3DSA:1.50.10.100 63 458 2.6E-123 T 23-04-2016 IPR012329 Polysaccharide lyase family 8, N-terminal GO:0005975|GO:0016837 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 PANTHER PTHR38481:SF1 68 782 9.3E-119 T 23-04-2016 SPYM18_RS04385 a45d08d46f0a42be9aedc01da166af6a 805 PANTHER PTHR38481 68 782 9.3E-119 T 23-04-2016 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 177 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 3.3E-48 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PANTHER PTHR11735:SF6 3 337 1.0E-140 T 23-04-2016 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 314 1.2E-126 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 SUPERFAMILY SSF53067 5 309 1.3E-37 T 23-04-2016 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 332 58.005 T 23-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 PANTHER PTHR11735 3 337 1.0E-140 T 23-04-2016 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 307 3.6E-103 T 23-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 Pfam PF00814 Glycoprotease family 27 307 2.2E-99 T 23-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 SPYM18_RS08350 6c0ec572723844764fa7f4a836433c50 342 Gene3D G3DSA:3.30.420.40 5 161 6.5E-48 T 23-04-2016 SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 Pfam PF06418 CTP synthase N-terminus 3 267 1.7E-129 T 23-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 Hamap MF_01227 CTP synthase [pyrG]. 2 533 51.344 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 SUPERFAMILY SSF52317 290 532 1.01E-74 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 Pfam PF00117 Glutamine amidotransferase class-I 302 527 3.0E-56 T 23-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 3.6E-252 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 Gene3D G3DSA:3.40.50.880 289 532 3.1E-96 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 SUPERFAMILY SSF52540 1 270 5.32E-125 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 Gene3D G3DSA:3.40.50.300 1 284 9.7E-141 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08435 7c2812e0f4d396a12d48ee8c864bcb3f 534 PANTHER PTHR11550 1 530 0.0 T 23-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 TIGRFAM TIGR00077 lspA: signal peptidase II 4 144 7.3E-38 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 2.9E-17 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 107 2.9E-17 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 2.9E-17 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 151 16.16 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 PANTHER PTHR33695 4 150 3.3E-45 T 23-04-2016 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 PANTHER PTHR33695:SF1 4 150 3.3E-45 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 Pfam PF01252 Signal peptidase (SPase) II 11 144 1.5E-34 T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS03820 a67d089e5208f5241b4e4be7d28fdeef 152 ProSitePatterns PS00855 Signal peptidases II signature. 95 107 - T 23-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 Gene3D G3DSA:3.30.390.50 242 328 8.6E-30 T 23-04-2016 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 PANTHER PTHR12561 1 329 1.2E-116 T 23-04-2016 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 PANTHER PTHR12561:SF3 1 329 1.2E-116 T 23-04-2016 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 320 8.8E-100 T 23-04-2016 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 UniPathway: UPA00537|UniPathway: UPA00537 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 46 154 1.3E-8 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 Gene3D G3DSA:3.90.1550.10 1 241 3.0E-87 T 23-04-2016 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 SUPERFAMILY SSF82649 242 328 4.03E-25 T 23-04-2016 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 244 326 2.0E-25 T 23-04-2016 IPR019491 Lipoate protein ligase, C-terminal UniPathway: UPA00537|UniPathway: UPA00537 SPYM18_RS04390 1d4e3cc139fdd163a8bb32448e98ef91 329 SUPERFAMILY SSF55681 1 241 1.63E-78 T 23-04-2016 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 PANTHER PTHR30217 1 428 1.0E-218 T 23-04-2016 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 SUPERFAMILY SSF51412 17 151 1.65E-5 T 23-04-2016 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 Pfam PF01136 Peptidase family U32 84 311 1.7E-87 T 23-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 Pfam PF16325 Peptidase family U32 C-terminal domain 326 407 1.4E-20 T 23-04-2016 IPR032525 Peptidase family U32, C-terminal KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 PANTHER PTHR30217:SF6 1 428 1.0E-218 T 23-04-2016 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 Gene3D G3DSA:3.20.20.70 13 102 2.8E-5 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 Gene3D G3DSA:3.20.20.70 135 160 2.8E-5 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02825 7a5c27da4aa89afd8d605525d3c8668b 428 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 23-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS03600 33d1fdbc1f73de80b1f49528ff916c34 304 PANTHER PTHR30168 4 302 3.3E-115 T 23-04-2016 SPYM18_RS03600 33d1fdbc1f73de80b1f49528ff916c34 304 Gene3D G3DSA:3.40.390.10 76 185 9.5E-5 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPYM18_RS03600 33d1fdbc1f73de80b1f49528ff916c34 304 Pfam PF04228 Putative neutral zinc metallopeptidase 1 297 6.1E-136 T 23-04-2016 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative SPYM18_RS06655 d73a9fafd460b069f445b7d0a6797fa4 129 Pfam PF00581 Rhodanese-like domain 37 122 1.6E-11 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS06655 d73a9fafd460b069f445b7d0a6797fa4 129 SUPERFAMILY SSF52821 11 122 9.82E-23 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS06655 d73a9fafd460b069f445b7d0a6797fa4 129 SMART SM00450 31 127 1.6E-7 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS06655 d73a9fafd460b069f445b7d0a6797fa4 129 Gene3D G3DSA:3.40.250.10 24 123 4.8E-20 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 Pfam PF01569 PAP2 superfamily 62 162 5.6E-13 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 SMART SM00014 58 165 3.1E-5 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 SUPERFAMILY SSF48317 28 164 1.44E-19 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 PANTHER PTHR14969 1 166 1.6E-26 T 23-04-2016 SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 Gene3D G3DSA:1.20.144.10 40 165 1.1E-17 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS08200 0557e43a510c5d9ce7416ed1580e9126 166 PANTHER PTHR14969:SF21 1 166 1.6E-26 T 23-04-2016 SPYM18_RS01625 a2d7871d36826865664640e4b69690c2 210 Pfam PF02384 N-6 DNA Methylase 49 160 2.1E-7 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPYM18_RS01625 a2d7871d36826865664640e4b69690c2 210 SUPERFAMILY SSF53335 32 157 1.23E-8 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 PANTHER PTHR10681 1 186 2.1E-88 T 23-04-2016 SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 PANTHER PTHR10681:SF121 1 186 2.1E-88 T 23-04-2016 SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 SUPERFAMILY SSF52833 1 186 5.61E-55 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 PIRSF PIRSF000239 1 186 2.3E-52 T 23-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 186 1.4E-101 T 23-04-2016 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 Pfam PF00578 AhpC/TSA family 4 132 5.6E-34 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 Gene3D G3DSA:3.40.30.10 3 182 3.4E-59 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS09150 b70ce618e9fd175691a60e6893e51a3f 186 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 181 1.2E-6 T 23-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Gene3D G3DSA:3.40.50.670 415 633 7.4E-89 T 23-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Gene3D G3DSA:3.30.230.10 231 403 5.8E-75 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 44 59 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 431 445 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 535 547 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 497 513 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 583 599 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 279 292 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 79 92 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 122 136 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR00418 DNA topoisomerase II family signature 515 532 7.0E-68 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 SUPERFAMILY SSF55874 14 226 1.97E-72 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 640 2.6E-29 T 23-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 23-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 183 1.6E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Pfam PF01751 Toprim domain 430 541 1.7E-17 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 15 25 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 385 405 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 323 339 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 481 490 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 231 253 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 604 616 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 620 636 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 205 218 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 371 385 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PRINTS PR01159 DNA gyrase subunit B signature 190 205 1.2E-75 T 23-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 SUPERFAMILY SSF56719 405 642 1.2E-83 T 23-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Gene3D G3DSA:3.30.565.10 15 226 5.8E-92 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 SUPERFAMILY SSF54211 232 402 4.36E-62 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 649 5.4E-297 T 23-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 SMART SM00387 40 184 7.0E-22 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 PANTHER PTHR10169 13 643 1.5E-302 T 23-04-2016 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 650 88.503 T 23-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 Pfam PF00204 DNA gyrase B 232 401 1.6E-65 T 23-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS03425 1597e1e4916732100d471cc7f2910842 650 SMART SM00433 44 644 0.0 T 23-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 SPYM18_RS07690 d5dcfc94f894d162838934f444f34285 210 Pfam PF02384 N-6 DNA Methylase 49 160 2.1E-10 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPYM18_RS07690 d5dcfc94f894d162838934f444f34285 210 SUPERFAMILY SSF53335 39 157 3.6E-10 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03255 823a03ce3690212c9be6e1a66a4ef476 395 Pfam PF05065 Phage capsid family 169 361 1.1E-20 T 23-04-2016 IPR024455 Phage capsid SPYM18_RS03255 823a03ce3690212c9be6e1a66a4ef476 395 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 7 388 1.4E-56 T 23-04-2016 IPR006444 Phage major capsid protein, HK97 SPYM18_RS03255 823a03ce3690212c9be6e1a66a4ef476 395 SUPERFAMILY SSF56563 142 389 6.67E-31 T 23-04-2016 SPYM18_RS04330 3fb1d02fcb029a0db0f1514059685b58 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 270 1.6E-29 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPYM18_RS04330 3fb1d02fcb029a0db0f1514059685b58 289 PANTHER PTHR32196 2 280 1.4E-73 T 23-04-2016 SPYM18_RS04330 3fb1d02fcb029a0db0f1514059685b58 289 PANTHER PTHR32196:SF27 2 280 1.4E-73 T 23-04-2016 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SUPERFAMILY SSF54814 292 357 4.45E-16 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 PANTHER PTHR22648:SF0 1 385 1.8E-140 T 23-04-2016 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 384 26.888 T 23-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Pfam PF08529 NusA N-terminal domain 4 124 1.2E-29 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Gene3D G3DSA:2.40.50.140 128 197 4.2E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SUPERFAMILY SSF54814 199 271 3.14E-22 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SMART SM00322 229 306 0.53 T 23-04-2016 IPR004087 K Homology domain GO:0003676 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SMART SM00322 315 380 3.8E-4 T 23-04-2016 IPR004087 K Homology domain GO:0003676 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SUPERFAMILY SSF50249 131 198 1.24E-16 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Pfam PF13184 NusA-like KH domain 229 310 9.9E-31 T 23-04-2016 IPR025249 KH domain, NusA-like GO:0003723 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 356 9.1E-111 T 23-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 SUPERFAMILY SSF69705 1 125 4.05E-34 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Gene3D G3DSA:3.30.300.20 198 289 1.2E-27 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Gene3D G3DSA:3.30.1480.10 1 124 1.7E-38 T 23-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 Gene3D G3DSA:3.30.300.20 291 359 2.7E-32 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS07440 2d7ce695d881786aba1e70e33e8afb1b 385 PANTHER PTHR22648 1 385 1.8E-140 T 23-04-2016 SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 1.1E-82 T 23-04-2016 IPR003797 DegV SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 PANTHER PTHR33434:SF3 1 281 3.9E-65 T 23-04-2016 SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 SUPERFAMILY SSF82549 1 282 1.96E-79 T 23-04-2016 SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 281 1.1E-84 T 23-04-2016 IPR003797 DegV SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 Gene3D G3DSA:3.30.1180.10 158 283 4.6E-40 T 23-04-2016 SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 PANTHER PTHR33434 1 281 3.9E-65 T 23-04-2016 SPYM18_RS08640 3870a5b36f26033f22e28a65766dd76c 286 Gene3D G3DSA:3.40.50.10170 1 154 7.6E-38 T 23-04-2016 SPYM18_RS02630 f1576f0448dad5353e13f6a74de21355 329 Pfam PF00535 Glycosyl transferase family 2 4 137 3.4E-10 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS02630 f1576f0448dad5353e13f6a74de21355 329 SUPERFAMILY SSF53448 4 227 3.62E-24 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02630 f1576f0448dad5353e13f6a74de21355 329 PANTHER PTHR10859 6 201 3.6E-13 T 23-04-2016 SPYM18_RS02630 f1576f0448dad5353e13f6a74de21355 329 Gene3D G3DSA:3.90.550.10 3 208 1.7E-7 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 202 3.4E-4 T 23-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 Gene3D G3DSA:3.30.360.10 144 318 6.9E-55 T 23-04-2016 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 SUPERFAMILY SSF55347 131 291 1.64E-15 T 23-04-2016 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 9.7E-23 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 SUPERFAMILY SSF51735 2 153 1.69E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 PANTHER PTHR22604:SF76 1 316 1.1E-61 T 23-04-2016 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 PANTHER PTHR22604 1 316 1.1E-61 T 23-04-2016 SPYM18_RS02130 02dda90f7874fbfb86941e4a56085b8b 319 Gene3D G3DSA:3.40.50.720 1 143 2.0E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 SUPERFAMILY SSF54736 52 121 3.66E-23 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 121 6.5E-44 T 23-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 92 4.0E-13 T 23-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 121 24.004 T 23-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 Gene3D G3DSA:1.20.5.710 2 51 2.8E-20 T 23-04-2016 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 SUPERFAMILY SSF48300 3 51 9.94E-14 T 23-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 4.2E-18 T 23-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 8.1E-30 T 23-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 SPYM18_RS04535 4384bd131d11f385e3673606dcac7d72 121 Gene3D G3DSA:3.30.1390.10 52 121 2.2E-31 T 23-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 Gene3D G3DSA:3.40.50.1980 155 305 2.2E-25 T 23-04-2016 SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 PANTHER PTHR30532:SF5 1 310 2.7E-81 T 23-04-2016 SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 Pfam PF01497 Periplasmic binding protein 57 282 6.4E-25 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 SUPERFAMILY SSF53807 50 301 1.37E-44 T 23-04-2016 SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 Gene3D G3DSA:3.40.50.1980 50 154 8.7E-22 T 23-04-2016 SPYM18_RS01985 b8e6b834d7baee4dbfa91704ab465aef 310 PANTHER PTHR30532 1 310 2.7E-81 T 23-04-2016 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 23-04-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 7 145 0.001 T 23-04-2016 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 SUPERFAMILY SSF160369 6 161 1.19E-49 T 23-04-2016 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 Pfam PF00466 Ribosomal protein L10 7 102 1.2E-26 T 23-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 PANTHER PTHR11560 1 163 3.6E-52 T 23-04-2016 SPYM18_RS04530 e8d91fee9677af13d7958b953e55f8a2 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 27.194 T 23-04-2016 IPR022973 Ribosomal protein L10 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 Pfam PF01029 NusB family 11 141 1.7E-31 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 9 143 1.9E-36 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 Gene3D G3DSA:1.10.940.10 7 144 4.1E-39 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 PANTHER PTHR11078 7 144 9.0E-39 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 7 145 22.726 T 23-04-2016 IPR011605 NusB antitermination factor GO:0006353 SPYM18_RS08125 e82404b3270b55a7d1128851cdf1bb69 150 SUPERFAMILY SSF48013 8 139 2.49E-33 T 23-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 730 750 - T 23-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 SUPERFAMILY SSF56796 461 872 3.14E-115 T 23-04-2016 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 SUPERFAMILY SSF53720 304 466 1.83E-81 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 SUPERFAMILY SSF53720 17 276 1.83E-81 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 PANTHER PTHR11496 377 874 1.2E-300 T 23-04-2016 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Gene3D G3DSA:3.40.50.1970 463 655 4.6E-64 T 23-04-2016 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Pfam PF00171 Aldehyde dehydrogenase family 16 416 4.4E-27 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Pfam PF00465 Iron-containing alcohol dehydrogenase 470 858 2.2E-113 T 23-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Gene3D G3DSA:3.40.605.10 16 233 5.1E-23 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Gene3D G3DSA:1.20.1090.10 657 870 1.5E-68 T 23-04-2016 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Gene3D G3DSA:3.40.309.10 326 418 1.4E-30 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 Gene3D G3DSA:3.40.309.10 234 281 1.4E-30 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 PANTHER PTHR11496:SF79 377 874 1.2E-300 T 23-04-2016 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 644 672 - T 23-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 SPYM18_RS00350 ea273f1b63458f9af29867ce963bf51e 880 PIRSF PIRSF000111 1 873 0.0 T 23-04-2016 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 SPYM18_RS04735 524eccb02c10ed0d9d680bc1826dc922 427 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 335 355 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 SPYM18_RS04735 524eccb02c10ed0d9d680bc1826dc922 427 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 12 418 7.1E-117 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 SPYM18_RS04735 524eccb02c10ed0d9d680bc1826dc922 427 TIGRFAM TIGR03173 pbuX: xanthine permease 17 420 2.1E-148 T 23-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 SPYM18_RS04735 524eccb02c10ed0d9d680bc1826dc922 427 Pfam PF00860 Permease family 13 383 7.3E-100 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS04735 524eccb02c10ed0d9d680bc1826dc922 427 PANTHER PTHR11119 13 427 1.8E-111 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 323 564 3.0E-70 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 Gene3D G3DSA:3.40.190.10 318 403 5.3E-30 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 PANTHER PTHR30177:SF2 7 277 7.3E-167 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 PANTHER PTHR30177:SF2 352 569 7.3E-167 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 Gene3D G3DSA:3.40.190.100 405 526 2.0E-40 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 PANTHER PTHR30177 352 569 7.3E-167 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 Gene3D G3DSA:1.10.3720.10 49 272 1.6E-36 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 SUPERFAMILY SSF53850 318 575 6.01E-82 T 23-04-2016 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 277 6.9E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 SUPERFAMILY SSF161098 88 273 1.26E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS00985 fbd92ecb32d5f4942fa2c120017a991f 575 PANTHER PTHR30177 7 277 7.3E-167 T 23-04-2016 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 SUPERFAMILY SSF55120 88 288 3.68E-59 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 Pfam PF00849 RNA pseudouridylate synthase 97 244 7.5E-33 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 PANTHER PTHR11079:SF73 92 283 9.6E-60 T 23-04-2016 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 23-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 42 288 7.8E-61 T 23-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS09095 f2d2c8caebd02770026851769f0496c4 303 PANTHER PTHR11079 92 283 9.6E-60 T 23-04-2016 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 Gene3D G3DSA:1.10.10.60 293 347 7.2E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 PANTHER PTHR11019 301 401 2.1E-17 T 23-04-2016 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 SUPERFAMILY SSF46689 298 345 1.04E-6 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 SMART SM00342 312 394 4.6E-23 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 SUPERFAMILY SSF46689 350 398 1.0E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 TIGRFAM TIGR04094 adjacent_YSIRK: YSIRK-targeted surface antigen transcriptional regulator 9 393 1.3E-80 T 23-04-2016 IPR024022 Transcription regulator HTH, surface antigen SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 Pfam PF12833 Helix-turn-helix domain 318 395 2.1E-14 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS00775 9c012c06321d85aad0b40822e16a7205 401 Gene3D G3DSA:1.10.10.60 353 393 2.1E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 PANTHER PTHR30425 1 311 5.6E-156 T 23-04-2016 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 304 1.4E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 Gene3D G3DSA:1.10.3720.10 25 309 8.0E-44 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 PANTHER PTHR30425:SF6 1 311 5.6E-156 T 23-04-2016 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 SUPERFAMILY SSF161098 32 297 2.35E-38 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05165 f4027101239aab4b920da60d73823459 311 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 21 305 1.3E-88 T 23-04-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 Gene3D G3DSA:1.10.1270.20 155 236 3.7E-35 T 23-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 SUPERFAMILY SSF75217 1 236 1.46E-94 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 108.474 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 Gene3D G3DSA:3.40.1280.10 1 154 8.4E-62 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 PANTHER PTHR32125 1 222 3.5E-112 T 23-04-2016 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 PIRSF PIRSF000386 1 238 3.5E-98 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 215 1.1E-65 T 23-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 1.1E-91 T 23-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 SPYM18_RS03910 63e5c5283feff39293599bafcb95f4f0 239 PANTHER PTHR32125:SF1 1 222 3.5E-112 T 23-04-2016 SPYM18_RS01740 c9b20237c9ec964e12f734a4053825e6 194 Pfam PF04630 Phage tail tube protein 22 164 1.4E-10 T 23-04-2016 IPR006724 Phage tail tube protein 1 SPYM18_RS01740 c9b20237c9ec964e12f734a4053825e6 194 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 1 193 2.8E-62 T 23-04-2016 IPR006490 Phage major tail protein, phi13 family SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 Pfam PF13545 Crp-like helix-turn-helix domain 159 220 4.8E-12 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 Pfam PF00027 Cyclic nucleotide-binding domain 34 116 1.2E-12 T 23-04-2016 IPR000595 Cyclic nucleotide-binding domain SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 SUPERFAMILY SSF46785 151 224 3.98E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 Gene3D G3DSA:2.60.120.10 7 146 2.1E-22 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 SUPERFAMILY SSF51206 23 148 1.13E-26 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 191 206 5.0E-5 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 175 191 5.0E-5 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 Gene3D G3DSA:1.10.10.10 150 217 4.3E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 SMART SM00419 169 217 7.9E-14 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS06745 5ab211d99ca32dee161d389d47519c36 226 PANTHER PTHR24567 1 224 7.0E-33 T 23-04-2016 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 SMART SM00358 161 228 5.5E-20 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 SUPERFAMILY SSF54768 115 227 6.44E-22 T 23-04-2016 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 227 1.5E-79 T 23-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 SUPERFAMILY SSF69065 7 163 3.31E-50 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 Pfam PF00035 Double-stranded RNA binding motif 161 227 1.9E-17 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 Gene3D G3DSA:1.10.1520.10 8 151 2.3E-46 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 Pfam PF14622 Ribonuclease-III-like 20 148 3.2E-34 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 PANTHER PTHR11207 1 227 1.3E-82 T 23-04-2016 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 Gene3D G3DSA:3.30.160.20 160 227 4.0E-26 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 Hamap MF_00104 Ribonuclease 3 [rnc]. 4 224 30.757 T 23-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 SPYM18_RS02585 b47b0dc05cb03463b5e1113106c8aabb 230 SMART SM00535 20 155 1.4E-57 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 PRINTS PR01898 Bacterial superantigen superfamily signature 79 105 3.9E-18 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 PRINTS PR01898 Bacterial superantigen superfamily signature 108 121 3.9E-18 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 PRINTS PR01898 Bacterial superantigen superfamily signature 150 163 3.9E-18 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 PRINTS PR01898 Bacterial superantigen superfamily signature 216 232 3.9E-18 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 PRINTS PR01898 Bacterial superantigen superfamily signature 163 177 3.9E-18 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 Gene3D G3DSA:2.40.50.110 44 113 1.6E-38 T 23-04-2016 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 Gene3D G3DSA:3.10.20.120 114 235 7.7E-39 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 SUPERFAMILY SSF50203 28 122 5.64E-27 T 23-04-2016 IPR008992 Enterotoxin GO:0009405 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 ProSitePatterns PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 150 173 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 SUPERFAMILY SSF54334 123 235 7.98E-30 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 Pfam PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain 39 117 1.0E-26 T 23-04-2016 IPR006173 Staphylococcal/Streptococcal toxin, OB-fold GO:0009405 SPYM18_RS01045 1757b55e38be2391511cbdd62818f5c2 236 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 129 233 1.6E-37 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 PANTHER PTHR10173:SF6 1 153 1.6E-66 T 23-04-2016 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 Gene3D G3DSA:3.30.1060.10 1 154 4.4E-70 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 PANTHER PTHR10173 1 153 1.6E-66 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 36.864 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 Pfam PF01625 Peptide methionine sulfoxide reductase 4 154 5.7E-62 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 153 4.4E-63 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS02225 6be4439cdef67dd8fe3e808dcf6fec86 169 SUPERFAMILY SSF55068 1 155 4.97E-70 T 23-04-2016 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 PANTHER PTHR34382:SF3 1 105 6.6E-65 T 23-04-2016 SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 SUPERFAMILY SSF46973 1 102 5.36E-34 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 TIGRFAM TIGR00823 EIIA-LAC: PTS system, lactose-specific IIa component 4 102 9.8E-46 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 PANTHER PTHR34382 1 105 6.6E-65 T 23-04-2016 SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 Gene3D G3DSA:1.20.58.80 2 102 1.2E-36 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 PIRSF PIRSF000699 1 105 1.1E-38 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS08575 04c4f4a45fc3a56c18ce3cb0125f831a 105 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 10 101 5.4E-34 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS04510 69205b7cca2e6c81d3ace1ed1a1e7999 200 SUPERFAMILY SSF55469 1 198 7.72E-47 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS04510 69205b7cca2e6c81d3ace1ed1a1e7999 200 Pfam PF00881 Nitroreductase family 8 180 6.8E-29 T 23-04-2016 IPR029479 Nitroreductase SPYM18_RS04510 69205b7cca2e6c81d3ace1ed1a1e7999 200 PANTHER PTHR23026:SF115 1 200 8.8E-43 T 23-04-2016 SPYM18_RS04510 69205b7cca2e6c81d3ace1ed1a1e7999 200 Gene3D G3DSA:3.40.109.10 1 198 1.8E-48 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS04510 69205b7cca2e6c81d3ace1ed1a1e7999 200 PANTHER PTHR23026 1 200 8.8E-43 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 PANTHER PTHR30570 20 286 8.2E-132 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 Pfam PF12849 PBP superfamily domain 31 258 4.3E-36 T 23-04-2016 IPR024370 PBP domain SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 Gene3D G3DSA:3.40.190.10 109 232 3.6E-40 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 PANTHER PTHR30570:SF4 20 286 8.2E-132 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 3 271 2.4E-84 T 23-04-2016 IPR011862 Phosphate binding protein GO:0006810 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 Gene3D G3DSA:3.40.190.10 233 274 1.4E-12 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 Gene3D G3DSA:3.40.190.10 5 92 1.4E-12 T 23-04-2016 SPYM18_RS05170 eefc7494ce07ae56b35af81821d61d5e 288 SUPERFAMILY SSF53850 33 277 2.36E-72 T 23-04-2016 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 PIRSF PIRSF002144 1 92 3.8E-32 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.494 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 Gene3D G3DSA:3.30.860.10 1 92 1.1E-41 T 23-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.1E-47 T 23-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 23-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 Pfam PF00203 Ribosomal protein S19 3 83 1.2E-37 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-23 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 SUPERFAMILY SSF54570 3 84 6.02E-35 T 23-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00390 0e626640b55ead65d5a65bcf781031d5 92 PANTHER PTHR11880 1 91 1.8E-54 T 23-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS05400 7d034c7073eb3f2c693a25e8e3428e7b 75 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 2 73 7.0E-19 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS05400 7d034c7073eb3f2c693a25e8e3428e7b 75 Pfam PF04531 Bacteriophage holin 2 74 4.2E-20 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 3.8E-71 T 23-04-2016 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 Gene3D G3DSA:3.40.1390.20 3 130 9.4E-47 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 PANTHER PTHR30305:SF1 1 310 3.8E-134 T 23-04-2016 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 Gene3D G3DSA:3.40.50.300 133 306 2.4E-69 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 302 3.9E-109 T 23-04-2016 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 Pfam PF02603 HPr Serine kinase N terminus 3 127 6.7E-40 T 23-04-2016 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 SUPERFAMILY SSF75138 3 130 1.57E-39 T 23-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 PANTHER PTHR30305 1 310 3.8E-134 T 23-04-2016 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 2 306 40.636 T 23-04-2016 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 SPYM18_RS02795 2b6a7db61dbfbba28c03a5b68cf48b24 310 SUPERFAMILY SSF53795 132 298 1.28E-37 T 23-04-2016 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 Gene3D G3DSA:3.10.560.10 71 141 1.4E-7 T 23-04-2016 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 Pfam PF12836 Helix-hairpin-helix motif 156 217 8.4E-22 T 23-04-2016 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 156 218 1.0E-21 T 23-04-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 SUPERFAMILY SSF47781 148 219 1.78E-27 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 PANTHER PTHR21180 12 220 7.1E-33 T 23-04-2016 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 Pfam PF10531 SLBB domain 77 130 1.6E-9 T 23-04-2016 IPR019554 Soluble ligand binding domain SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 Gene3D G3DSA:1.10.150.280 142 219 1.5E-22 T 23-04-2016 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 SMART SM00278 167 186 0.21 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS06130 602aefe950236b30c08f830ee1d3a9c3 220 SMART SM00278 197 216 0.31 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 Gene3D G3DSA:3.90.76.10 53 183 2.5E-30 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 PANTHER PTHR30290 292 537 5.0E-90 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 PANTHER PTHR30290 71 276 5.0E-90 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 SUPERFAMILY SSF53850 39 512 1.26E-89 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 Gene3D G3DSA:3.40.190.10 184 303 4.3E-31 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 PANTHER PTHR30290:SF27 71 276 5.0E-90 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 Gene3D G3DSA:3.10.105.10 304 481 6.2E-32 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 PIRSF PIRSF002741 1 527 2.6E-77 T 23-04-2016 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 PANTHER PTHR30290:SF27 292 537 5.0E-90 T 23-04-2016 SPYM18_RS08895 3ef4f500af15c13711417291a0d00a39 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 412 6.2E-69 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 PANTHER PTHR30535:SF15 33 287 2.9E-87 T 23-04-2016 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 Gene3D G3DSA:3.40.50.1980 146 287 1.2E-30 T 23-04-2016 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 Pfam PF01497 Periplasmic binding protein 36 266 2.2E-40 T 23-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 Gene3D G3DSA:3.40.50.1980 34 145 7.0E-20 T 23-04-2016 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 SUPERFAMILY SSF53807 30 284 2.16E-51 T 23-04-2016 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 TIGRFAM TIGR03659 IsdE: heme ABC transporter, heme-binding protein isdE 8 287 3.1E-122 T 23-04-2016 IPR019957 ABC transporter, high-affinity heme uptake system protein IsdE GO:0015886|GO:0016020|GO:0020037 SPYM18_RS08055 069776abc30b1d686b36a268652f88ff 294 PANTHER PTHR30535 33 287 2.9E-87 T 23-04-2016 SPYM18_RS01465 c50d663e9561205219aa3a6d2d5e1e9f 456 PANTHER PTHR30588 1 452 2.5E-126 T 23-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 SPYM18_RS01465 c50d663e9561205219aa3a6d2d5e1e9f 456 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 11 438 3.2E-112 T 23-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 SPYM18_RS01465 c50d663e9561205219aa3a6d2d5e1e9f 456 Pfam PF05525 Branched-chain amino acid transport protein 4 453 4.7E-158 T 23-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 SPYM18_RS09260 214a15f54d46b5031cb2034e954174a0 169 PANTHER PTHR39173 1 165 1.4E-42 T 23-04-2016 SPYM18_RS09260 214a15f54d46b5031cb2034e954174a0 169 Pfam PF13302 Acetyltransferase (GNAT) domain 2 147 1.7E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS09260 214a15f54d46b5031cb2034e954174a0 169 SUPERFAMILY SSF55729 1 152 5.59E-22 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS09260 214a15f54d46b5031cb2034e954174a0 169 Gene3D G3DSA:3.40.630.30 2 152 1.7E-21 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 Gene3D G3DSA:3.40.1280.10 96 247 3.2E-52 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 11 247 7.4E-81 T 23-04-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 Gene3D G3DSA:3.30.1330.30 5 81 3.2E-23 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 SUPERFAMILY SSF75217 81 247 4.71E-49 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 12 85 4.0E-16 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 SUPERFAMILY SSF55315 8 82 4.53E-18 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 PANTHER PTHR12029 11 248 2.8E-79 T 23-04-2016 SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 SMART SM00967 12 86 2.1E-15 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SPYM18_RS08650 7c2fd421143bf0510a5f8e175f4ac5fc 248 Pfam PF00588 SpoU rRNA Methylase family 102 241 1.2E-40 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 Pfam PF00072 Response regulator receiver domain 3 122 4.3E-10 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 Gene3D G3DSA:2.40.50.40 140 208 2.6E-13 T 23-04-2016 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 Gene3D G3DSA:3.40.50.2300 1 137 2.3E-12 T 23-04-2016 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 PANTHER PTHR26402:SF577 1 133 5.2E-34 T 23-04-2016 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 SUPERFAMILY SSF52172 1 158 4.7E-9 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 PANTHER PTHR26402 1 133 5.2E-34 T 23-04-2016 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 SMART SM00850 148 242 1.5E-17 T 23-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 SMART SM00448 1 122 1.3E-5 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS01130 b9fd1ca5481d4c7e00b647898910cbbc 245 Pfam PF04397 LytTr DNA-binding domain 151 241 4.8E-22 T 23-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 Pfam PF13394 4Fe-4S single cluster domain 110 203 8.9E-8 T 23-04-2016 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 349 68.971 T 23-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 PANTHER PTHR30544 2 354 1.2E-166 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 PANTHER PTHR30544:SF5 2 354 1.2E-166 T 23-04-2016 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 Gene3D G3DSA:3.20.20.70 96 331 2.3E-14 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 1 354 7.3E-130 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 SUPERFAMILY SSF102114 97 308 1.44E-12 T 23-04-2016 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 PIRSF PIRSF006004 1 359 3.4E-133 T 23-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 SPYM18_RS06680 f2829ccbac11fa335240c547a6fdb6a9 359 Pfam PF04055 Radical SAM superfamily 105 270 1.2E-15 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PANTHER PTHR31964 1 148 3.5E-34 T 23-04-2016 SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 Pfam PF00582 Universal stress protein family 5 144 1.1E-33 T 23-04-2016 IPR006016 UspA GO:0006950 SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 Gene3D G3DSA:3.40.50.620 5 144 6.8E-39 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PIRSF PIRSF006276 1 146 4.3E-20 T 23-04-2016 IPR006015 Universal stress protein A SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 SUPERFAMILY SSF52402 5 146 4.94E-33 T 23-04-2016 SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PANTHER PTHR31964:SF45 1 148 3.5E-34 T 23-04-2016 SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PRINTS PR01438 Universal stress protein signature 122 144 2.4E-18 T 23-04-2016 IPR006015 Universal stress protein A SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PRINTS PR01438 Universal stress protein signature 104 116 2.4E-18 T 23-04-2016 IPR006015 Universal stress protein A SPYM18_RS07990 868f93081ecf2da2c00d22c0edf71368 150 PRINTS PR01438 Universal stress protein signature 5 23 2.4E-18 T 23-04-2016 IPR006015 Universal stress protein A SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 23-04-2016 IPR030390 RNA methyltransferase TrmA, active site SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 Gene3D G3DSA:3.40.50.150 247 448 5.0E-61 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 23-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 442 1.5E-130 T 23-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 89 450 1.1E-20 T 23-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 PANTHER PTHR11061:SF35 3 450 2.1E-249 T 23-04-2016 SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 SUPERFAMILY SSF53335 68 449 4.33E-71 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 SUPERFAMILY SSF50249 2 58 1.83E-12 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 Gene3D G3DSA:2.40.50.140 3 79 2.0E-25 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 Pfam PF01938 TRAM domain 4 59 3.8E-6 T 23-04-2016 IPR002792 TRAM domain SPYM18_RS06935 727c1aaa32307361d68f6ceb748fa370 451 PANTHER PTHR11061 3 450 2.1E-249 T 23-04-2016 SPYM18_RS06240 b8598d7a450d1a7a8d834fb0965ee022 75 Pfam PF04531 Bacteriophage holin 2 74 3.2E-20 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS06240 b8598d7a450d1a7a8d834fb0965ee022 75 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 2 73 4.1E-19 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS03335 b8598d7a450d1a7a8d834fb0965ee022 75 Pfam PF04531 Bacteriophage holin 2 74 3.2E-20 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS03335 b8598d7a450d1a7a8d834fb0965ee022 75 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 2 73 4.1E-19 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 Pfam PF08282 haloacid dehalogenase-like hydrolase 15 261 3.7E-47 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 14 261 6.2E-45 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PANTHER PTHR11071 216 386 1.2E-91 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PANTHER PTHR11071 411 464 1.2E-91 T 23-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 14 234 9.4E-15 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 Gene3D G3DSA:2.40.100.10 275 465 4.2E-65 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PANTHER PTHR11071:SF282 216 386 1.2E-91 T 23-04-2016 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PANTHER PTHR11071:SF282 411 464 1.2E-91 T 23-04-2016 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 SUPERFAMILY SSF50891 282 385 1.02E-55 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 SUPERFAMILY SSF50891 413 464 1.02E-55 T 23-04-2016 IPR029000 Cyclophilin-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 286 463 1.7E-45 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 Gene3D G3DSA:3.40.50.1000 170 268 2.2E-46 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 Gene3D G3DSA:3.40.50.1000 6 82 2.2E-46 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 367 382 1.5E-18 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 325 337 1.5E-18 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 299 314 1.5E-18 T 23-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 SPYM18_RS07040 2b58934e9543ae0d90e1b8ba94913108 466 SUPERFAMILY SSF56784 5 265 1.19E-55 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 PANTHER PTHR22778 2 307 2.3E-108 T 23-04-2016 SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 Pfam PF12368 Rhodanase C-terminal 227 293 4.0E-13 T 23-04-2016 IPR022111 Rhodanase, C-terminal SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 SUPERFAMILY SSF52821 110 252 6.02E-33 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 Pfam PF00581 Rhodanese-like domain 122 215 7.4E-11 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 272 39.733 T 23-04-2016 IPR020936 Uncharacterised protein family UPF0176 SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 SMART SM00450 120 221 2.8E-19 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 PANTHER PTHR22778:SF21 2 307 2.3E-108 T 23-04-2016 SPYM18_RS04215 fd44d331d403c65b5b9585e882326690 328 Gene3D G3DSA:3.40.250.10 104 233 4.2E-33 T 23-04-2016 IPR001763 Rhodanese-like domain SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 SUPERFAMILY SSF57716 4 61 9.98E-21 T 23-04-2016 SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 24.86 T 23-04-2016 IPR023053 Ribosomal protein S14, type Z SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 PANTHER PTHR19836 15 61 9.4E-34 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 Gene3D G3DSA:4.10.830.10 2 61 1.0E-26 T 23-04-2016 SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 Pfam PF00253 Ribosomal protein S14p/S29e 13 60 8.3E-24 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00435 f52220f9c37e9cc9513810ab5aafba9b 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 23-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 PANTHER PTHR24423:SF375 13 156 7.9E-47 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 PANTHER PTHR24423:SF375 189 410 7.9E-47 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 PANTHER PTHR24423 13 156 7.9E-47 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 PANTHER PTHR24423 189 410 7.9E-47 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 SUPERFAMILY SSF103190 37 164 4.32E-34 T 23-04-2016 IPR029151 Periplasmic sensor domain-like SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 SUPERFAMILY SSF55890 319 407 4.71E-9 T 23-04-2016 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 Gene3D G3DSA:3.30.450.20 214 282 2.6E-4 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 Gene3D G3DSA:1.10.287.130 311 368 1.6E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 Pfam PF17203 Single cache domain 3 38 162 1.7E-24 T 23-04-2016 IPR033463 Single cache domain 3 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 316 363 3.5E-10 T 23-04-2016 SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 SMART SM00091 211 279 0.0095 T 23-04-2016 IPR000014 PAS domain SPYM18_RS04610 727d878aeefed8667ad0d3b3619ff0b3 513 Gene3D G3DSA:3.30.450.20 31 164 2.2E-41 T 23-04-2016 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PANTHER PTHR22855:SF17 29 284 2.3E-135 T 23-04-2016 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PANTHER PTHR22855 29 284 2.3E-135 T 23-04-2016 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 Gene3D G3DSA:3.90.226.10 29 284 5.8E-69 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 205 222 3.7E-35 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 168 186 3.7E-35 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 148 3.7E-35 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 256 265 3.7E-35 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 234 245 3.7E-35 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 SUPERFAMILY SSF52096 34 284 2.24E-72 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 Pfam PF01039 Carboxyl transferase domain 67 246 5.0E-18 T 23-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 286 38.657 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS07850 5ae8b8393d339bc25256613e9c22d9b8 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 25 284 1.1E-105 T 23-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 389 1.1E-132 T 23-04-2016 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD UniPathway: UPA00556 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 PANTHER PTHR40039 2 416 9.6E-108 T 23-04-2016 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 Pfam PF04915 DltD N-terminal region 37 98 4.1E-27 T 23-04-2016 IPR006999 DltD, N-terminal UniPathway: UPA00556 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 PIRSF PIRSF021438 1 392 1.2E-154 T 23-04-2016 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD UniPathway: UPA00556 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 Pfam PF04914 DltD C-terminal region 263 390 7.2E-50 T 23-04-2016 IPR006998 DltD, C-terminal UniPathway: UPA00556 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 Pfam PF04918 DltD central region 99 261 1.5E-45 T 23-04-2016 IPR007002 DltD, central domain UniPathway: UPA00556 SPYM18_RS05735 f3b8db98f2a21135681f9e5e2bcd5866 416 PANTHER PTHR40039:SF1 2 416 9.6E-108 T 23-04-2016 SPYM18_RS00260 137a020f4ddd5c8c15dc2f73d5f7ecdc 80 Pfam PF00550 Phosphopantetheine attachment site 11 64 6.4E-7 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS00260 137a020f4ddd5c8c15dc2f73d5f7ecdc 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 74 4.0E-7 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 SPYM18_RS00260 137a020f4ddd5c8c15dc2f73d5f7ecdc 80 Gene3D G3DSA:1.10.1200.10 1 78 2.3E-19 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS00260 137a020f4ddd5c8c15dc2f73d5f7ecdc 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 14.719 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 SPYM18_RS00260 137a020f4ddd5c8c15dc2f73d5f7ecdc 80 SUPERFAMILY SSF47336 1 79 9.29E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 Pfam PF00232 Glycosyl hydrolase family 1 3 460 1.7E-112 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PANTHER PTHR10353:SF73 4 460 1.7E-220 T 23-04-2016 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 SUPERFAMILY SSF51445 2 457 2.33E-142 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PANTHER PTHR10353 4 460 1.7E-220 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 1.6E-11 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 290 304 1.6E-11 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 424 1.6E-11 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 386 397 1.6E-11 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 PRINTS PR00131 Glycosyl hydrolase family 1 signature 362 370 1.6E-11 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06905 071d7e3bfe7536fbb66522eec5899bd4 480 Gene3D G3DSA:3.20.20.80 3 457 1.1E-125 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-25 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PRINTS PR00315 GTP-binding elongation factor signature 61 69 2.0E-25 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PRINTS PR00315 GTP-binding elongation factor signature 81 91 2.0E-25 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PRINTS PR00315 GTP-binding elongation factor signature 97 108 2.0E-25 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PRINTS PR00315 GTP-binding elongation factor signature 134 143 2.0E-25 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 3.3E-222 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 1.5E-13 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Pfam PF03143 Elongation factor Tu C-terminal domain 302 396 1.2E-31 T 23-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PANTHER PTHR23115 1 397 2.5E-244 T 23-04-2016 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Gene3D G3DSA:2.40.30.10 212 302 2.9E-37 T 23-04-2016 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Pfam PF03144 Elongation factor Tu domain 2 228 297 5.1E-16 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 1.8E-58 T 23-04-2016 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 PANTHER PTHR23115:SF112 1 397 2.5E-244 T 23-04-2016 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 398 59.381 T 23-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 SUPERFAMILY SSF50447 206 305 1.96E-29 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 SUPERFAMILY SSF52540 6 222 1.99E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 SUPERFAMILY SSF50465 306 397 6.62E-35 T 23-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Gene3D G3DSA:2.40.30.10 305 396 1.5E-44 T 23-04-2016 SPYM18_RS02900 241691aa1bd93637f87bc4a975701f09 398 Gene3D G3DSA:3.40.50.300 3 211 1.3E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05265 e40a876951652dce0acdae4b04fddece 82 Pfam PF04226 Transglycosylase associated protein 33 76 1.4E-11 T 23-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 TIGRFAM TIGR01083 nth: endonuclease III 7 197 4.2E-76 T 23-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 PANTHER PTHR10359 20 213 3.3E-78 T 23-04-2016 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 PIRSF PIRSF001435 5 215 6.0E-56 T 23-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Hamap MF_00942 Endonuclease III [nth]. 1 212 37.854 T 23-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 SMART SM00478 40 188 4.9E-56 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 SUPERFAMILY SSF48150 15 212 8.32E-72 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 SMART SM00525 189 209 1.4E-4 T 23-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 190 206 3.6E-6 T 23-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Pfam PF00633 Helix-hairpin-helix motif 102 129 5.5E-9 T 23-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 190 206 - T 23-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Gene3D G3DSA:1.10.1670.10 125 211 2.5E-35 T 23-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 171 1.2E-22 T 23-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 Gene3D G3DSA:1.10.340.30 26 124 5.4E-37 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS04270 20339d9cef4c26a714c2292c563167fd 218 ProSitePatterns PS01155 Endonuclease III family signature. 104 133 - T 23-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 311 371 1.7E-20 T 23-04-2016 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PANTHER PTHR22807 1 337 2.0E-119 T 23-04-2016 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 164 176 1.4E-22 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 214 230 1.4E-22 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 283 1.4E-22 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 97 107 1.4E-22 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 68 82 1.4E-22 T 23-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 Pfam PF01189 16S rRNA methyltransferase RsmB/F 86 282 1.5E-47 T 23-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 PANTHER PTHR22807:SF36 1 337 2.0E-119 T 23-04-2016 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 SUPERFAMILY SSF53335 2 282 1.82E-63 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 390 436 6.8E-13 T 23-04-2016 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 Gene3D G3DSA:3.40.50.150 80 282 2.3E-58 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05175 f53d1b74d4b0bb372ccd9ff4b8280b0d 436 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 4 82 2.5E-18 T 23-04-2016 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220 6 16 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220 362 375 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220 41 304 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220:SF374 6 16 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220:SF374 362 375 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 PANTHER PTHR24220:SF374 41 304 3.2E-153 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 Pfam PF00571 CBS domain 337 390 9.4E-5 T 23-04-2016 IPR000644 CBS domain SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 391 5.7E-141 T 23-04-2016 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 Gene3D G3DSA:3.10.580.10 272 390 2.2E-17 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 SUPERFAMILY SSF54631 274 395 3.89E-16 T 23-04-2016 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 SUPERFAMILY SSF52540 40 270 9.54E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 SMART SM00382 53 250 2.6E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 Gene3D G3DSA:3.40.50.300 3 265 3.2E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00980 6d73bfcefe8180d5d25e3055f56b80bf 398 Pfam PF00005 ABC transporter 46 192 2.8E-35 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS06285 24960b7c37b4f3491ff03dea77f87ae8 186 SMART SM00507 48 96 8.8E-6 T 23-04-2016 IPR003615 HNH nuclease SPYM18_RS06285 24960b7c37b4f3491ff03dea77f87ae8 186 SMART SM00497 108 177 0.0093 T 23-04-2016 IPR003647 Intron encoded nuclease repeat SPYM18_RS06285 24960b7c37b4f3491ff03dea77f87ae8 186 SUPERFAMILY SSF54060 2 99 1.17E-26 T 23-04-2016 SPYM18_RS06285 24960b7c37b4f3491ff03dea77f87ae8 186 Pfam PF13392 HNH endonuclease 53 96 1.9E-14 T 23-04-2016 IPR003615 HNH nuclease SPYM18_RS06370 461c1b633a047df121a5e63cbdad49dc 422 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 18 346 3.0E-14 T 23-04-2016 IPR021145 Portal protein, SPP1 Gp6-like SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 PANTHER PTHR33280 1 79 1.3E-34 T 23-04-2016 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 1.7E-19 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 Pfam PF01197 Ribosomal protein L31 1 78 1.5E-28 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 PRINTS PR01249 Ribosomal protein L31 signature 2 19 5.2E-19 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 PRINTS PR01249 Ribosomal protein L31 signature 59 77 5.2E-19 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 PRINTS PR01249 Ribosomal protein L31 signature 44 59 5.2E-19 T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 SUPERFAMILY SSF143800 1 79 6.67E-24 T 23-04-2016 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 26.965 T 23-04-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03380 3d91339d034f4cb6b768de727eda5cdf 86 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 23-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04595 c541a20e37be12d2a07882b85bea7c3e 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 77 244 2.8E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04595 c541a20e37be12d2a07882b85bea7c3e 258 Gene3D G3DSA:1.10.3720.10 2 256 2.4E-52 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04595 c541a20e37be12d2a07882b85bea7c3e 258 SUPERFAMILY SSF161098 4 248 2.52E-47 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04595 c541a20e37be12d2a07882b85bea7c3e 258 PANTHER PTHR30222 8 256 1.3E-71 T 23-04-2016 SPYM18_RS04595 c541a20e37be12d2a07882b85bea7c3e 258 PANTHER PTHR30222:SF1 8 256 1.3E-71 T 23-04-2016 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Pfam PF01131 DNA topoisomerase 151 564 2.3E-130 T 23-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Hamap MF_00952 DNA topoisomerase 1 [topA]. 26 649 55.211 T 23-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PANTHER PTHR11390:SF27 24 703 0.0 T 23-04-2016 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:3.40.50.140 25 157 2.4E-44 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 302 325 - T 23-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Pfam PF01751 Toprim domain 28 136 1.2E-29 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:1.10.460.10 473 577 3.4E-56 T 23-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:1.10.460.10 636 639 3.4E-56 T 23-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:1.10.460.10 158 205 3.4E-56 T 23-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 8.3E-36 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 8.3E-36 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 489 503 8.3E-36 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 100 113 8.3E-36 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 316 325 8.3E-36 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 674 705 0.2 T 23-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 633 671 6.3E-12 T 23-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 594 629 4.0E-14 T 23-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:3.30.65.10 592 635 1.2E-19 T 23-04-2016 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 PANTHER PTHR11390 24 703 0.0 T 23-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 SUPERFAMILY SSF57783 589 629 2.55E-13 T 23-04-2016 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 SMART SM00493 26 126 1.0E-27 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 SMART SM00437 265 526 2.0E-106 T 23-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 SUPERFAMILY SSF56712 26 605 4.84E-189 T 23-04-2016 IPR023405 DNA topoisomerase, type IA, core domain SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 28 627 1.5E-239 T 23-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 SMART SM00436 127 215 3.9E-49 T 23-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:2.70.20.10 340 472 1.1E-30 T 23-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPYM18_RS04860 01b11684c98b5f92be2f3dc9d4a6500a 709 Gene3D G3DSA:2.70.20.10 207 336 8.7E-30 T 23-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 23-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 SUPERFAMILY SSF53738 153 256 1.02E-23 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 3.4E-12 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 3.4E-12 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 3.4E-12 T 23-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 2.4E-192 T 23-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 PANTHER PTHR22573 1 448 1.2E-162 T 23-04-2016 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Gene3D G3DSA:3.40.120.10 3 151 6.4E-46 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 366 2.7E-31 T 23-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 SUPERFAMILY SSF53738 3 168 2.51E-42 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 3.3E-42 T 23-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Gene3D G3DSA:3.40.120.10 176 249 3.0E-21 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 SUPERFAMILY SSF55957 357 447 1.7E-24 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 PANTHER PTHR22573:SF15 1 448 1.2E-162 T 23-04-2016 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 44.093 T 23-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 443 1.3E-16 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Gene3D G3DSA:3.30.310.50 369 445 4.8E-21 T 23-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 SUPERFAMILY SSF53738 257 365 5.89E-31 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Gene3D G3DSA:3.40.120.10 250 368 1.1E-37 T 23-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS04415 99132161ee8442d37b00f725d9e182dc 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 166 253 1.9E-14 T 23-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1173 22.49 T 23-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 SMART SM00968 518 637 9.3E-38 T 23-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 Gene3D G3DSA:3.40.50.300 1 163 5.9E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 Gene3D G3DSA:3.40.50.300 1021 1176 5.9E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 Pfam PF06470 SMC proteins Flexible Hinge Domain 519 634 2.5E-25 T 23-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 PANTHER PTHR18937 1 485 0.0 T 23-04-2016 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 PANTHER PTHR18937 509 1177 0.0 T 23-04-2016 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1171 0.0 T 23-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1164 6.4E-61 T 23-04-2016 IPR003395 RecF/RecN/SMC, N-terminal SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 SUPERFAMILY SSF52540 1057 1173 4.33E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 SUPERFAMILY SSF52540 1 210 4.33E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 PANTHER PTHR18937:SF251 1 485 0.0 T 23-04-2016 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 PANTHER PTHR18937:SF251 509 1177 0.0 T 23-04-2016 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 SUPERFAMILY SSF75553 480 684 1.26E-48 T 23-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 SPYM18_RS02590 e81cad0c63b4bfa9a04b9f21c74e45b7 1179 PIRSF PIRSF005719 1 1179 1.5E-273 T 23-04-2016 IPR024704 Structural maintenance of chromosomes protein SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 23-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 5.8E-52 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PIRSF PIRSF000149 1 336 1.7E-113 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 7.3E-64 T 23-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 1.7E-131 T 23-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 SMART SM00846 3 152 2.2E-82 T 23-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 SUPERFAMILY SSF55347 151 314 2.05E-66 T 23-04-2016 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 4.1E-31 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.1E-31 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 4.1E-31 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.1E-31 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 4.1E-31 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 Gene3D G3DSA:3.30.360.10 161 316 7.5E-70 T 23-04-2016 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 SUPERFAMILY SSF51735 3 168 8.14E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PANTHER PTHR10836 1 334 1.3E-234 T 23-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 PANTHER PTHR10836:SF57 1 334 1.3E-234 T 23-04-2016 SPYM18_RS01270 be851e84d003c3ac5997809e4871f214 336 Gene3D G3DSA:3.40.50.720 1 160 1.0E-67 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 PANTHER PTHR18895:SF3 17 312 1.4E-89 T 23-04-2016 SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 307 3.6E-113 T 23-04-2016 SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 300 1.3E-74 T 23-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 Gene3D G3DSA:3.40.50.150 110 301 5.7E-46 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 SUPERFAMILY SSF53335 69 306 9.03E-41 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 4 307 35.138 T 23-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 PIRSF PIRSF000401 2 309 7.9E-111 T 23-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 SPYM18_RS08840 885dc996b0a71b382af1489e3d0f4c94 317 PANTHER PTHR18895 17 312 1.4E-89 T 23-04-2016 SPYM18_RS01075 9e94d7712fa3350fd5a18fb01832aad4 149 Pfam PF12802 MarR family 33 89 8.6E-10 T 23-04-2016 SPYM18_RS01075 9e94d7712fa3350fd5a18fb01832aad4 149 SUPERFAMILY SSF46785 4 139 1.75E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01075 9e94d7712fa3350fd5a18fb01832aad4 149 SMART SM00347 24 126 1.4E-7 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS01075 9e94d7712fa3350fd5a18fb01832aad4 149 Gene3D G3DSA:1.10.10.10 3 140 3.9E-31 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 PANTHER PTHR18895 69 275 2.3E-79 T 23-04-2016 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 SUPERFAMILY SSF53335 3 273 3.41E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 271 7.2E-81 T 23-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 Gene3D G3DSA:1.10.8.10 1 84 2.0E-7 T 23-04-2016 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 1 275 38.127 T 23-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 Pfam PF05175 Methyltransferase small domain 102 189 2.3E-19 T 23-04-2016 IPR007848 Methyltransferase small domain GO:0008168 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 Gene3D G3DSA:3.40.50.150 86 273 9.7E-65 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 PANTHER PTHR18895:SF64 69 275 2.3E-79 T 23-04-2016 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPYM18_RS04760 d41e7cbe4988c6d7ddbbbe8cad30d502 279 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 42 273 1.3E-61 T 23-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 235 43.178 T 23-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 PANTHER PTHR21234 1 235 3.7E-67 T 23-04-2016 IPR018017 Nucleoside phosphorylase SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 Gene3D G3DSA:3.40.50.1580 8 234 4.3E-81 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 Pfam PF01048 Phosphorylase superfamily 16 218 5.7E-43 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 5.2E-89 T 23-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 23-04-2016 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 SUPERFAMILY SSF53167 2 235 1.7E-86 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS04110 aace2197d0116dd886e19862e659f5e2 237 PANTHER PTHR21234:SF8 1 235 3.7E-67 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 Gene3D G3DSA:1.10.10.10 4 45 7.3E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 SMART SM00420 4 48 4.5E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 Gene3D G3DSA:3.40.50.1360 66 210 9.2E-15 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 SUPERFAMILY SSF46785 5 56 1.15E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 PANTHER PTHR30363:SF4 1 217 3.8E-81 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 28 46 1.1E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 14 28 1.1E-8 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 SMART SM01134 63 220 6.6E-65 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 PANTHER PTHR30363 1 217 3.8E-81 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 SUPERFAMILY SSF100950 64 217 4.5E-35 T 23-04-2016 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 Pfam PF08220 DeoR-like helix-turn-helix domain 4 51 9.7E-15 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS03930 9927a7d5e2780feed795f8da962beebb 237 Pfam PF00455 DeoR C terminal sensor domain 65 216 1.7E-47 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain SPYM18_RS02535 504d4136dd930c5ab59840e3fccdaa21 191 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 8 186 6.6E-68 T 23-04-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00563+2.7.-.- SPYM18_RS02535 504d4136dd930c5ab59840e3fccdaa21 191 SMART SM01120 30 187 5.5E-71 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS02535 504d4136dd930c5ab59840e3fccdaa21 191 Pfam PF02734 DAK2 domain 30 186 1.4E-47 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS02535 504d4136dd930c5ab59840e3fccdaa21 191 PANTHER PTHR28629 1 191 1.3E-58 T 23-04-2016 SPYM18_RS02535 504d4136dd930c5ab59840e3fccdaa21 191 SUPERFAMILY SSF101473 2 188 1.83E-56 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 Gene3D G3DSA:2.40.50.140 25 85 6.2E-4 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 439 28.211 T 23-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 PANTHER PTHR30008:SF0 1 445 4.9E-156 T 23-04-2016 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 Pfam PF13742 OB-fold nucleic acid binding domain 5 97 1.8E-24 T 23-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 PANTHER PTHR30008 1 445 4.9E-156 T 23-04-2016 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 Pfam PF02601 Exonuclease VII, large subunit 122 436 5.0E-94 T 23-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 SPYM18_RS06540 d2c7fb80087797e4e4049b9d7423ce87 446 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 344 6.3E-126 T 23-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS05490 4221e8e6e0046361c335a2473de81fa0 177 Pfam PF14265 Domain of unknown function (DUF4355) 25 145 1.0E-28 T 23-04-2016 IPR025580 Protein of unknown function DUF4355 SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 PIRSF PIRSF019455 1 129 1.6E-33 T 23-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 SUPERFAMILY SSF46785 1 120 1.27E-25 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 3 132 6.0E-43 T 23-04-2016 IPR014071 Copper transport repressor CopY/TcrY SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 PANTHER PTHR34134 1 128 7.6E-22 T 23-04-2016 SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 PANTHER PTHR34134:SF1 1 128 7.6E-22 T 23-04-2016 SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 Pfam PF03965 Penicillinase repressor 4 117 1.5E-33 T 23-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 SPYM18_RS07410 97d0b642d93d78ea05b09bbe88a88bb4 144 Gene3D G3DSA:1.10.10.10 1 75 6.2E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 SUPERFAMILY SSF56112 8 276 1.75E-79 T 23-04-2016 IPR011009 Protein kinase-like domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Gene3D G3DSA:3.30.200.20 2 78 6.9E-26 T 23-04-2016 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Gene3D G3DSA:1.10.510.10 79 261 2.6E-52 T 23-04-2016 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 23-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 23-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 SMART SM00220 12 270 1.0E-64 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 SMART SM00740 368 435 1.2E-19 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 SMART SM00740 509 589 25.0 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 SMART SM00740 436 508 1.5E-11 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 PANTHER PTHR24362:SF160 1 341 6.3E-114 T 23-04-2016 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Pfam PF03793 PASTA domain 372 434 2.6E-15 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Pfam PF03793 PASTA domain 441 506 2.8E-11 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Pfam PF03793 PASTA domain 512 588 1.2E-9 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 Pfam PF00069 Protein kinase domain 12 237 2.4E-54 T 23-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 SPYM18_RS07060 06151911ee05387c11108f2bb45feef1 632 PANTHER PTHR24362 1 341 6.3E-114 T 23-04-2016 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 Gene3D G3DSA:3.40.50.1000 59 265 5.9E-67 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 PIRSF PIRSF019271 1 284 1.2E-107 T 23-04-2016 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 50 257 8.8E-58 T 23-04-2016 IPR005519 Acid phosphatase, class B-like SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 PANTHER PTHR31284:SF10 241 257 1.9E-62 T 23-04-2016 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 PANTHER PTHR31284:SF10 41 223 1.9E-62 T 23-04-2016 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 PANTHER PTHR31284 241 257 1.9E-62 T 23-04-2016 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 PANTHER PTHR31284 41 223 1.9E-62 T 23-04-2016 SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 SUPERFAMILY SSF56784 69 264 5.51E-47 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS08395 c108f8530d67b2b97637f547d679f303 284 TIGRFAM TIGR01533 lipo_e_P4: 5'-nucleotidase, lipoprotein e(P4) family 1 283 1.4E-120 T 23-04-2016 IPR006423 5-nucleotidase lipoprotein e(P4) GO:0009279 SPYM18_RS04395 bac66f6e02867a699b733a34dd5caa4b 263 Gene3D G3DSA:3.40.50.880 31 208 8.9E-18 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS04395 bac66f6e02867a699b733a34dd5caa4b 263 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 19 214 2.1E-46 T 23-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 SPYM18_RS04395 bac66f6e02867a699b733a34dd5caa4b 263 PANTHER PTHR21343 8 263 1.2E-105 T 23-04-2016 SPYM18_RS04395 bac66f6e02867a699b733a34dd5caa4b 263 PANTHER PTHR21343:SF9 8 263 1.2E-105 T 23-04-2016 SPYM18_RS04395 bac66f6e02867a699b733a34dd5caa4b 263 SUPERFAMILY SSF52317 34 207 8.06E-29 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 Pfam PF00281 Ribosomal protein L5 25 81 3.6E-26 T 23-04-2016 IPR031310 Ribosomal protein L5, N-terminal SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 PANTHER PTHR11994 1 179 2.3E-93 T 23-04-2016 SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.6 T 23-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 2.1E-39 T 23-04-2016 IPR031309 Ribosomal protein L5, C-terminal SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 Gene3D G3DSA:3.30.1440.10 3 179 7.7E-76 T 23-04-2016 IPR022803 Ribosomal protein L5 domain SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 PIRSF PIRSF002161 1 180 2.6E-65 T 23-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 SUPERFAMILY SSF55282 4 179 1.18E-74 T 23-04-2016 IPR022803 Ribosomal protein L5 domain SPYM18_RS00430 7534b8d85856347d27556b6518b82eb9 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 23-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PANTHER PTHR30075 1 305 6.8E-247 T 23-04-2016 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 SUPERFAMILY SSF55681 6 284 4.72E-129 T 23-04-2016 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 1.8E-64 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 Gene3D G3DSA:1.20.58.180 209 290 1.6E-38 T 23-04-2016 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 291 7.8E-156 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 Gene3D G3DSA:3.30.930.10 2 207 1.7E-100 T 23-04-2016 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 283 1.5E-145 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS07310 8b64f357c82717d1925a3773b3e33fbc 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 57.753 T 23-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 Gene3D G3DSA:3.40.309.10 239 427 5.7E-55 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 SUPERFAMILY SSF53720 3 455 1.57E-124 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 PANTHER PTHR11699 1 454 1.1E-208 T 23-04-2016 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 Gene3D G3DSA:3.40.605.10 3 238 2.0E-58 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 PANTHER PTHR11699:SF205 1 454 1.1E-208 T 23-04-2016 SPYM18_RS04500 9951314bd1580ffc99633cc6fb7a2787 465 Pfam PF00171 Aldehyde dehydrogenase family 3 448 6.7E-116 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 Pfam PF05636 HIGH Nucleotidyl Transferase 1 348 4.4E-108 T 23-04-2016 IPR008513 Uncharacterised protein family UPF0348 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 PANTHER PTHR37825:SF1 2 362 9.6E-92 T 23-04-2016 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 Gene3D G3DSA:3.40.50.620 1 219 1.7E-72 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 Hamap MF_01539 UPF0348 protein . 2 361 34.255 T 23-04-2016 IPR008513 Uncharacterised protein family UPF0348 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 PANTHER PTHR37825 2 362 9.6E-92 T 23-04-2016 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 SUPERFAMILY SSF52374 10 138 6.19E-17 T 23-04-2016 SPYM18_RS01435 020cc8cb05afca966d170b807215917a 368 SUPERFAMILY SSF52374 186 212 6.19E-17 T 23-04-2016 SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 SMART SM00345 16 75 1.1E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 Gene3D G3DSA:3.30.70.1450 138 209 1.7E-16 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 SUPERFAMILY SSF116726 135 209 1.18E-15 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 Gene3D G3DSA:1.10.10.10 9 79 5.0E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 SUPERFAMILY SSF46785 11 84 2.15E-12 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 Pfam PF02080 TrkA-C domain 145 207 3.5E-10 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPYM18_RS05235 46d7d03c8644d5a7ae87139b334a96cb 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.5E-10 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 Gene3D G3DSA:2.60.120.260 761 902 5.8E-5 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 SUPERFAMILY SSF51445 111 407 3.04E-34 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 ProSitePatterns PS01095 Chitinases family 18 active site. 227 235 - T 23-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 Gene3D G3DSA:3.20.20.80 105 415 4.1E-53 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 Gene3D G3DSA:3.80.10.10 549 599 1.2E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS08105 319774b607e9705894981ac3a7401986 975 Gene3D G3DSA:3.80.10.10 478 514 1.2E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS01460 343c2e9e68b049bbe27f7cd2852cc6fc 230 PANTHER PTHR30450:SF1 26 230 9.8E-81 T 23-04-2016 SPYM18_RS01460 343c2e9e68b049bbe27f7cd2852cc6fc 230 PANTHER PTHR30450 26 230 9.8E-81 T 23-04-2016 SPYM18_RS01460 343c2e9e68b049bbe27f7cd2852cc6fc 230 SUPERFAMILY SSF161098 23 217 2.75E-35 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01460 343c2e9e68b049bbe27f7cd2852cc6fc 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 60 228 2.0E-15 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01460 343c2e9e68b049bbe27f7cd2852cc6fc 230 Gene3D G3DSA:1.10.3720.10 21 228 1.0E-32 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08465 277be6e934179d785a2ec3024436e5ab 254 PANTHER PTHR20858 1 248 2.5E-53 T 23-04-2016 SPYM18_RS08465 277be6e934179d785a2ec3024436e5ab 254 SUPERFAMILY SSF53613 1 248 3.43E-51 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS08465 277be6e934179d785a2ec3024436e5ab 254 Pfam PF08543 Phosphomethylpyrimidine kinase 14 247 5.6E-56 T 23-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 SPYM18_RS08465 277be6e934179d785a2ec3024436e5ab 254 Gene3D G3DSA:3.40.1190.20 6 248 1.2E-56 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 SMART SM00829 10 334 5.0E-7 T 23-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 4.3E-32 T 23-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 Pfam PF00107 Zinc-binding dehydrogenase 173 298 7.3E-24 T 23-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 23-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 Gene3D G3DSA:3.90.180.10 1 165 1.6E-64 T 23-04-2016 IPR011032 GroES-like SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 Gene3D G3DSA:3.40.50.720 166 284 1.2E-30 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 SUPERFAMILY SSF51735 135 304 7.78E-39 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 SUPERFAMILY SSF50129 1 170 1.0E-53 T 23-04-2016 IPR011032 GroES-like SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 PANTHER PTHR11695:SF498 13 336 4.7E-138 T 23-04-2016 SPYM18_RS00355 8f2bf1e5f1df3a38f3664a1fcdc30c66 338 PANTHER PTHR11695 13 336 4.7E-138 T 23-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Pfam PF01624 MutS domain I 8 118 3.4E-43 T 23-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SUPERFAMILY SSF48334 254 552 8.24E-87 T 23-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Pfam PF05190 MutS family domain IV 415 506 1.2E-27 T 23-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SUPERFAMILY SSF52540 554 785 7.58E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SMART SM00533 270 578 1.3E-102 T 23-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Gene3D G3DSA:1.10.1420.10 249 455 1.6E-52 T 23-04-2016 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Pfam PF05188 MutS domain II 126 239 5.9E-20 T 23-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Gene3D G3DSA:3.40.1170.10 4 118 2.0E-48 T 23-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Pfam PF05192 MutS domain III 256 546 5.3E-42 T 23-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SUPERFAMILY SSF55271 4 114 4.19E-41 T 23-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Gene3D G3DSA:3.30.420.110 125 246 6.3E-31 T 23-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 PANTHER PTHR11361 1 849 0.0 T 23-04-2016 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SUPERFAMILY SSF53150 119 265 8.63E-33 T 23-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 SMART SM00534 595 782 2.0E-109 T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Pfam PF00488 MutS domain V 598 785 4.3E-81 T 23-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 849 0.0 T 23-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Gene3D G3DSA:3.40.50.300 554 785 1.5E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 PANTHER PTHR11361:SF86 1 849 0.0 T 23-04-2016 SPYM18_RS09330 cf593faa14f85bcf478d315c2465e261 851 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 843 23.623 T 23-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 PIRSF PIRSF002070 1 126 7.0E-37 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 Gene3D G3DSA:2.40.50.140 1 116 1.1E-43 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 34.176 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 SUPERFAMILY SSF50249 1 130 5.14E-46 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 111 1.9E-40 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 Pfam PF00436 Single-strand binding protein family 2 103 2.9E-35 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 SPYM18_RS01640 2045cf8cc6ff933a51c577c842f10015 130 PANTHER PTHR10302 1 127 7.1E-36 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS01900 1bb2150522bb6be3dab23c351345eb95 234 PANTHER PTHR33969:SF2 1 233 8.3E-61 T 23-04-2016 SPYM18_RS01900 1bb2150522bb6be3dab23c351345eb95 234 Pfam PF02616 Segregation and condensation protein ScpA 18 227 7.1E-27 T 23-04-2016 IPR003768 Segregation and condensation protein A SPYM18_RS01900 1bb2150522bb6be3dab23c351345eb95 234 Hamap MF_01805 Segregation and condensation protein A [scpA]. 1 233 24.766 T 23-04-2016 IPR003768 Segregation and condensation protein A SPYM18_RS01900 1bb2150522bb6be3dab23c351345eb95 234 PANTHER PTHR33969 1 233 8.3E-61 T 23-04-2016 SPYM18_RS01895 715dd00e69c1e019afbf27612bd290a2 248 SUPERFAMILY SSF56349 4 247 1.24E-18 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS01895 715dd00e69c1e019afbf27612bd290a2 248 Hamap MF_01817 Tyrosine recombinase XerD-like. 1 246 37.715 T 23-04-2016 IPR020876 Tyrosine recombinase XerD-like GO:0005737 SPYM18_RS01895 715dd00e69c1e019afbf27612bd290a2 248 Gene3D G3DSA:1.10.443.10 114 247 4.3E-15 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS01895 715dd00e69c1e019afbf27612bd290a2 248 Pfam PF00589 Phage integrase family 113 247 3.4E-6 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS01895 715dd00e69c1e019afbf27612bd290a2 248 Gene3D G3DSA:1.10.150.130 3 78 3.2E-6 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PANTHER PTHR10381 1 194 9.8E-110 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 SUPERFAMILY SSF52096 8 194 3.8E-68 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 Pfam PF00574 Clp protease 10 192 2.6E-79 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PANTHER PTHR10381:SF22 1 194 9.8E-110 T 23-04-2016 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 193 39.751 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 110 123 - T 23-04-2016 IPR033135 ClpP, histidine active site SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 3.9E-44 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.9E-44 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 3.9E-44 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 109 128 3.9E-44 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 3.9E-44 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 Gene3D G3DSA:3.90.226.10 9 194 2.7E-78 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS02010 dc042461ca22432ef9d97170876f227b 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 88 99 - T 23-04-2016 IPR018215 ClpP, Ser active site SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 5.8E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 5.8E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 5.8E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 5.8E-19 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PANTHER PTHR11405:SF16 1 307 1.8E-115 T 23-04-2016 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 Gene3D G3DSA:3.40.50.1370 12 149 5.4E-42 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 SUPERFAMILY SSF53671 10 307 1.96E-85 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PANTHER PTHR11405 1 307 1.8E-115 T 23-04-2016 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 158 302 9.9E-21 T 23-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 12 152 3.6E-32 T 23-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 81 90 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 138 155 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 43 65 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 2.2E-28 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 Gene3D G3DSA:3.40.50.1370 150 282 2.2E-44 T 23-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 12 304 1.7E-88 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS03840 0b34e4b7305d0f80a1a4aab5e2759e9a 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 306 38.242 T 23-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 Pfam PF04851 Type III restriction enzyme, res subunit 257 427 4.5E-32 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 86 705 5.0E-103 T 23-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 711 978 2.7E-36 T 23-04-2016 IPR022625 Type-1 restriction enzyme R protein, C-terminal SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 Gene3D G3DSA:3.40.50.300 251 437 1.2E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 SUPERFAMILY SSF52540 247 429 2.53E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 SUPERFAMILY SSF52540 528 555 1.51E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 SUPERFAMILY SSF52540 393 459 1.51E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 SMART SM00487 253 454 4.7E-16 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 SUPERFAMILY SSF52540 587 677 1.51E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 PANTHER PTHR30195 8 855 3.5E-114 T 23-04-2016 SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 PANTHER PTHR30195:SF16 8 855 3.5E-114 T 23-04-2016 SPYM18_RS08515 eda9c1e76d11107a96967d7a2dda94aa 992 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 202 2.3E-21 T 23-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 ProSitePatterns PS01229 Hypothetical cof family signature 2. 218 240 - T 23-04-2016 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 ProSitePatterns PS01228 Hypothetical cof family signature 1. 4 15 - T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 264 3.6E-59 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 SUPERFAMILY SSF56784 1 268 2.27E-66 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 237 1.1E-32 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 Gene3D G3DSA:3.40.50.1000 183 269 1.1E-56 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 Gene3D G3DSA:3.40.50.1000 1 74 1.1E-56 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 Gene3D G3DSA:3.30.1240.10 86 182 3.5E-12 T 23-04-2016 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 PANTHER PTHR10000:SF16 1 270 3.7E-71 T 23-04-2016 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 PANTHER PTHR10000 1 270 3.7E-71 T 23-04-2016 SPYM18_RS07350 2272bcdbea61fd21acb61bbcdd30a244 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 264 1.6E-61 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Gene3D G3DSA:3.30.70.1050 1 119 3.9E-33 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Hamap MF_00303 Trigger factor [tig]. 1 427 21.896 T 23-04-2016 IPR005215 Trigger factor GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 3.5E-46 T 23-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 TIGRFAM TIGR00115 tig: trigger factor 13 420 4.9E-127 T 23-04-2016 IPR005215 Trigger factor GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 PIRSF PIRSF003095 1 427 1.3E-118 T 23-04-2016 IPR005215 Trigger factor GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 SUPERFAMILY SSF54534 89 243 4.71E-36 T 23-04-2016 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 PANTHER PTHR30560 1 427 1.2E-112 T 23-04-2016 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Gene3D G3DSA:3.10.50.40 158 217 6.5E-10 T 23-04-2016 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 SUPERFAMILY SSF109998 250 426 1.57E-37 T 23-04-2016 IPR027304 Trigger factor/SurA domain SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 4.2E-38 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 PANTHER PTHR30560:SF3 1 427 1.2E-112 T 23-04-2016 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Gene3D G3DSA:1.10.3120.10 218 400 8.1E-58 T 23-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 SUPERFAMILY SSF102735 1 128 8.76E-33 T 23-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 SPYM18_RS08445 f97a04afde9935483b4e106f7144d7d5 427 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 231 5.4E-15 T 23-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.622 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 Pfam PF01245 Ribosomal protein L19 4 112 2.4E-51 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 SUPERFAMILY SSF50104 1 114 1.6E-46 T 23-04-2016 IPR008991 Translation protein SH3-like domain SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 113 1.7E-48 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 PANTHER PTHR15680 1 115 1.2E-52 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 23-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03405 acde9ada45561fd06022a7a7c2ad3e06 115 PIRSF PIRSF002191 1 115 9.7E-51 T 23-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PANTHER PTHR11404 5 201 1.0E-96 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PIRSF PIRSF000349 1 201 7.5E-80 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 23-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 89 4.5E-29 T 23-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 SUPERFAMILY SSF54719 92 200 3.27E-45 T 23-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 98 195 1.4E-41 T 23-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 SUPERFAMILY SSF46609 1 90 1.57E-33 T 23-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 8.0E-27 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 8.0E-27 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 8.0E-27 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 8.0E-27 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 8.0E-27 T 23-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 SPYM18_RS06115 2ea2c74d334974a83b5ee9c1efb1cd48 201 Gene3D G3DSA:1.10.287.990 20 89 4.6E-29 T 23-04-2016 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 SUPERFAMILY SSF52540 5 240 1.69E-76 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 PANTHER PTHR24220 7 246 8.3E-129 T 23-04-2016 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 PIRSF PIRSF039085 2 246 3.7E-109 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 PANTHER PTHR24220:SF327 7 246 8.3E-129 T 23-04-2016 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 Gene3D G3DSA:3.40.50.300 4 242 1.2E-82 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 Pfam PF00005 ABC transporter 21 170 1.4E-36 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01275 0c456393935d0f024f592b7a74e111af 246 SMART SM00382 30 218 1.2E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04975 474c493480b69ecf82ab9fafaa2a9d0f 113 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 6 103 2.0E-41 T 23-04-2016 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like SPYM18_RS04975 474c493480b69ecf82ab9fafaa2a9d0f 113 SUPERFAMILY SSF88659 7 109 1.16E-32 T 23-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 SPYM18_RS04975 474c493480b69ecf82ab9fafaa2a9d0f 113 Hamap MF_00245 UPF0122 protein . 6 106 20.777 T 23-04-2016 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like SPYM18_RS04975 474c493480b69ecf82ab9fafaa2a9d0f 113 PANTHER PTHR40083 5 113 3.9E-42 T 23-04-2016 SPYM18_RS04975 474c493480b69ecf82ab9fafaa2a9d0f 113 Gene3D G3DSA:1.10.10.10 2 109 9.2E-42 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05810 5596c53bcaf84ea284bcc92fc21bc9fd 231 Pfam PF04973 Nicotinamide mononucleotide transporter 35 218 2.4E-26 T 23-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SPYM18_RS05810 5596c53bcaf84ea284bcc92fc21bc9fd 231 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 35 220 2.2E-17 T 23-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 316 44.157 T 23-04-2016 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 SUPERFAMILY SSF51735 4 148 3.42E-53 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 176 182 - T 23-04-2016 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PANTHER PTHR11540:SF3 4 326 3.0E-147 T 23-04-2016 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 1.7E-47 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PRINTS PR00086 L-lactate dehydrogenase signature 174 187 1.7E-47 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PRINTS PR00086 L-lactate dehydrogenase signature 144 162 1.7E-47 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PRINTS PR00086 L-lactate dehydrogenase signature 34 58 1.7E-47 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PRINTS PR00086 L-lactate dehydrogenase signature 120 140 1.7E-47 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 Gene3D G3DSA:3.40.50.720 8 148 5.3E-52 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 149 318 7.6E-40 T 23-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 SUPERFAMILY SSF56327 147 315 2.88E-53 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 309 9.7E-122 T 23-04-2016 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PIRSF PIRSF000102 4 323 2.5E-102 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 PANTHER PTHR11540 4 326 3.0E-147 T 23-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 Gene3D G3DSA:3.90.110.10 149 315 3.9E-57 T 23-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 SPYM18_RS04805 44004f6840bb2b8803ce9b172e4c6b0c 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 146 2.6E-47 T 23-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 SPYM18_RS02955 bda535b55dc36c9ae5b807035d537244 273 PANTHER PTHR32502 7 272 1.7E-51 T 23-04-2016 SPYM18_RS02955 bda535b55dc36c9ae5b807035d537244 273 PANTHER PTHR32502:SF6 7 272 1.7E-51 T 23-04-2016 SPYM18_RS02955 bda535b55dc36c9ae5b807035d537244 273 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 272 1.4E-82 T 23-04-2016 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 PANTHER PTHR30135:SF3 1 321 4.2E-129 T 23-04-2016 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 Hamap MF_00973 Gluconeogenesis factor. 2 322 34.554 T 23-04-2016 IPR010119 Gluconeogenesis factor SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 PANTHER PTHR30135 1 321 4.2E-129 T 23-04-2016 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 SUPERFAMILY SSF142338 3 317 5.36E-97 T 23-04-2016 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 Pfam PF01933 Uncharacterised protein family UPF0052 7 294 3.1E-93 T 23-04-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 Gene3D G3DSA:3.40.50.10680 76 321 7.6E-56 T 23-04-2016 SPYM18_RS03055 81f75e4a9d8dcdf6c99d0c123af2f655 325 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 7 320 3.4E-119 T 23-04-2016 IPR010119 Gluconeogenesis factor SPYM18_RS02605 2e878eeb035cb8292f1ed37317382c6d 278 Pfam PF01261 Xylose isomerase-like TIM barrel 21 229 2.4E-19 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS02605 2e878eeb035cb8292f1ed37317382c6d 278 SUPERFAMILY SSF51658 3 275 2.98E-33 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS02605 2e878eeb035cb8292f1ed37317382c6d 278 Gene3D G3DSA:3.20.20.150 1 277 7.5E-56 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Gene3D G3DSA:3.40.50.300 206 274 7.1E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Gene3D G3DSA:3.40.50.300 4 134 7.1E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 371 2.0E-146 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 SUPERFAMILY SSF52540 3 309 2.64E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PANTHER PTHR23305:SF12 1 371 3.1E-203 T 23-04-2016 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Pfam PF01926 50S ribosome-binding GTPase 5 114 1.4E-23 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 SUPERFAMILY SSF81271 287 371 9.16E-35 T 23-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Gene3D G3DSA:3.10.20.30 275 371 1.7E-48 T 23-04-2016 IPR012675 Beta-grasp domain SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Pfam PF06071 Protein of unknown function (DUF933) 287 370 2.7E-39 T 23-04-2016 IPR013029 Domain of unknown function DUF933 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 371 43.95 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PIRSF PIRSF006641 1 371 1.9E-153 T 23-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 8.0E-36 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 8.0E-36 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 8.0E-36 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 8.0E-36 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 Gene3D G3DSA:1.10.150.300 135 205 1.7E-30 T 23-04-2016 IPR023192 TGS-like domain SPYM18_RS00020 8140658d5a5c2b1da4b35127225d242d 371 PANTHER PTHR23305 1 371 3.1E-203 T 23-04-2016 SPYM18_RS02560 722dbd39af09c60c13f98916d1186d17 415 Gene3D G3DSA:3.30.300.30 313 407 4.1E-8 T 23-04-2016 SPYM18_RS02560 722dbd39af09c60c13f98916d1186d17 415 Gene3D G3DSA:3.40.50.980 100 252 1.8E-18 T 23-04-2016 SPYM18_RS02560 722dbd39af09c60c13f98916d1186d17 415 Pfam PF00501 AMP-binding enzyme 92 281 1.9E-14 T 23-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 SPYM18_RS02560 722dbd39af09c60c13f98916d1186d17 415 SUPERFAMILY SSF56801 4 407 4.97E-44 T 23-04-2016 SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 Gene3D G3DSA:3.30.1390.20 1 59 1.3E-28 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 SUPERFAMILY SSF55129 1 59 3.27E-19 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.9E-18 T 23-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 PIRSF PIRSF002211 1 60 4.1E-27 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 PANTHER PTHR15892 1 60 6.1E-24 T 23-04-2016 SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 18.601 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-04-2016 IPR018038 Ribosomal protein L30, conserved site SPYM18_RS00460 5c0405fd802d398e53f9bd259707f227 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 4.1E-27 T 23-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS08415 312dc523fa95d42b390398634f0f5690 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 2.9E-21 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08415 312dc523fa95d42b390398634f0f5690 62 Gene3D G3DSA:4.10.1160.10 19 62 3.4E-22 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08415 312dc523fa95d42b390398634f0f5690 62 SUPERFAMILY SSF143800 1 61 2.94E-24 T 23-04-2016 SPYM18_RS08415 312dc523fa95d42b390398634f0f5690 62 Pfam PF00830 Ribosomal L28 family 3 58 1.3E-21 T 23-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 SPYM18_RS08415 312dc523fa95d42b390398634f0f5690 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.068 T 23-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS04410 e3d9cb3ecfd0521467c63206852d0273 318 PANTHER PTHR37804 1 297 1.0E-39 T 23-04-2016 SPYM18_RS04410 e3d9cb3ecfd0521467c63206852d0273 318 Pfam PF07949 YbbR-like protein 52 135 5.9E-8 T 23-04-2016 IPR012505 YbbR-like SPYM18_RS04410 e3d9cb3ecfd0521467c63206852d0273 318 Pfam PF07949 YbbR-like protein 237 313 5.2E-9 T 23-04-2016 IPR012505 YbbR-like SPYM18_RS04410 e3d9cb3ecfd0521467c63206852d0273 318 Pfam PF07949 YbbR-like protein 150 228 2.1E-7 T 23-04-2016 IPR012505 YbbR-like SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 PANTHER PTHR10302 1 107 5.3E-30 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 Pfam PF00436 Single-strand binding protein family 3 102 2.5E-27 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 Gene3D G3DSA:2.40.50.140 1 114 2.1E-35 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 PIRSF PIRSF002070 1 121 5.4E-30 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 30.532 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 114 3.0E-27 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS00725 c9a2c3d01bedc539700b9af9510219ae 131 SUPERFAMILY SSF50249 1 131 3.77E-36 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 Gene3D G3DSA:1.20.58.110 1 76 4.5E-23 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 PANTHER PTHR33398 2 76 1.2E-26 T 23-04-2016 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 77 13.396 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 76 3.0E-23 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 SUPERFAMILY SSF46992 3 76 2.09E-23 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 76 1.6E-20 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05125 99e619161eaa339265c5af6ae9dc6def 77 Pfam PF01649 Ribosomal protein S20 2 76 4.2E-21 T 23-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS07495 6ff0b5c903d6d3cc09ba0470082406c6 153 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 6 127 4.3E-33 T 23-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SPYM18_RS07495 6ff0b5c903d6d3cc09ba0470082406c6 153 PANTHER PTHR33540 1 144 1.1E-39 T 23-04-2016 SPYM18_RS07495 6ff0b5c903d6d3cc09ba0470082406c6 153 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 6 132 1.8E-35 T 23-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 SPYM18_RS07495 6ff0b5c903d6d3cc09ba0470082406c6 153 Gene3D G3DSA:3.40.50.300 3 143 9.7E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07495 6ff0b5c903d6d3cc09ba0470082406c6 153 SUPERFAMILY SSF52540 23 143 1.5E-21 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 2.3E-137 T 23-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 PANTHER PTHR30307:SF0 2 341 1.3E-173 T 23-04-2016 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 SUPERFAMILY SSF111337 1 341 2.62E-136 T 23-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 Pfam PF02547 Queuosine biosynthesis protein 4 341 1.9E-138 T 23-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.107 T 23-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 PANTHER PTHR30307 2 341 1.3E-173 T 23-04-2016 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 Gene3D G3DSA:2.40.10.240 64 143 4.2E-30 T 23-04-2016 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 Gene3D G3DSA:3.40.1780.10 178 341 4.3E-99 T 23-04-2016 SPYM18_RS06095 8f100ea129b6914b97ed6983c1908bba 342 Gene3D G3DSA:3.40.1780.10 1 62 4.3E-99 T 23-04-2016 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 PANTHER PTHR26402:SF522 1 137 6.4E-31 T 23-04-2016 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 Gene3D G3DSA:3.40.50.2300 1 127 6.7E-25 T 23-04-2016 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 PIRSF PIRSF006171 1 221 1.2E-76 T 23-04-2016 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 SUPERFAMILY SSF52172 1 134 1.71E-27 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 SMART SM00448 1 114 2.3E-17 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 Pfam PF00072 Response regulator receiver domain 3 114 5.2E-19 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 SUPERFAMILY SSF46785 161 206 2.89E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04605 a5658a713e9b5c499d9acd207116db4d 221 PANTHER PTHR26402 1 137 6.4E-31 T 23-04-2016 SPYM18_RS01950 29586a0827915c071875e15632013575 184 PANTHER PTHR35276:SF1 3 184 4.1E-51 T 23-04-2016 SPYM18_RS01950 29586a0827915c071875e15632013575 184 SUPERFAMILY SSF53335 9 143 1.08E-19 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01950 29586a0827915c071875e15632013575 184 Gene3D G3DSA:3.40.50.150 14 146 1.1E-16 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01950 29586a0827915c071875e15632013575 184 PANTHER PTHR35276 3 184 4.1E-51 T 23-04-2016 SPYM18_RS01950 29586a0827915c071875e15632013575 184 Pfam PF06962 Putative rRNA methylase 44 178 5.7E-50 T 23-04-2016 IPR010719 Putative rRNA methylase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- SPYM18_RS09360 5f296ea7b240b46563871fc8fc5ee7e5 292 PANTHER PTHR33545:SF7 3 286 4.8E-81 T 23-04-2016 SPYM18_RS09360 5f296ea7b240b46563871fc8fc5ee7e5 292 PANTHER PTHR33545 3 286 4.8E-81 T 23-04-2016 SPYM18_RS09360 5f296ea7b240b46563871fc8fc5ee7e5 292 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 12 218 1.6E-56 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS09360 5f296ea7b240b46563871fc8fc5ee7e5 292 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 223 275 1.3E-18 T 23-04-2016 IPR019264 Domain of unknown function DUF2179 SPYM18_RS09360 5f296ea7b240b46563871fc8fc5ee7e5 292 PIRSF PIRSF006483 1 284 5.0E-70 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS03485 2fddb212dc926cbbc481e2b7688405f2 372 Pfam PF12698 ABC-2 family transporter protein 18 363 5.9E-40 T 23-04-2016 SPYM18_RS03485 2fddb212dc926cbbc481e2b7688405f2 372 Gene3D G3DSA:3.40.1710.10 41 118 6.0E-4 T 23-04-2016 SPYM18_RS03485 2fddb212dc926cbbc481e2b7688405f2 372 PANTHER PTHR30294:SF21 1 368 2.2E-57 T 23-04-2016 SPYM18_RS03485 2fddb212dc926cbbc481e2b7688405f2 372 PANTHER PTHR30294 1 368 2.2E-57 T 23-04-2016 SPYM18_RS05630 f48065b4af461e00dbc74af5dc64f12a 58 SMART SM00530 4 57 3.2E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05630 f48065b4af461e00dbc74af5dc64f12a 58 Gene3D G3DSA:1.10.260.40 2 57 1.9E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05630 f48065b4af461e00dbc74af5dc64f12a 58 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 4 56 2.4E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05630 f48065b4af461e00dbc74af5dc64f12a 58 SUPERFAMILY SSF47413 3 57 4.79E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 PANTHER PTHR23046 2 162 2.2E-88 T 23-04-2016 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 Pfam PF00731 AIR carboxylase 6 151 2.4E-64 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 SUPERFAMILY SSF52255 5 158 9.16E-65 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 6 154 5.7E-65 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 6 159 32.321 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 PANTHER PTHR23046:SF2 2 162 2.2E-88 T 23-04-2016 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 Gene3D G3DSA:3.40.50.7700 2 160 4.9E-75 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 SMART SM01001 4 155 9.3E-97 T 23-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 SPYM18_RS00305 cb7647a15f95bd6e8c50e59e0cc521b5 163 PIRSF PIRSF001338 1 163 2.3E-68 T 23-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 SUPERFAMILY SSF54334 124 234 6.15E-33 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 Gene3D G3DSA:3.10.20.120 114 235 1.4E-40 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 128 233 4.5E-31 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR00279 Bacterial toxin signature 112 124 1.1E-5 T 23-04-2016 IPR006177 Staphylococcal/streptococcal toxin, bacterial GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR00279 Bacterial toxin signature 151 167 1.1E-5 T 23-04-2016 IPR006177 Staphylococcal/streptococcal toxin, bacterial GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 Pfam PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain 42 119 5.3E-12 T 23-04-2016 IPR006173 Staphylococcal/Streptococcal toxin, OB-fold GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 ProSitePatterns PS00277 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin signature 1. 114 123 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 Gene3D G3DSA:2.40.50.110 47 113 1.3E-38 T 23-04-2016 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 SUPERFAMILY SSF50203 32 122 1.52E-29 T 23-04-2016 IPR008992 Enterotoxin GO:0009405 SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR01898 Bacterial superantigen superfamily signature 81 107 1.7E-15 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR01898 Bacterial superantigen superfamily signature 151 164 1.7E-15 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR01898 Bacterial superantigen superfamily signature 110 123 1.7E-15 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR01898 Bacterial superantigen superfamily signature 164 178 1.7E-15 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 PRINTS PR01898 Bacterial superantigen superfamily signature 216 232 1.7E-15 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS03350 eddf3459cfa6d1c198b57e21887c4b7d 235 ProSitePatterns PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 151 174 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 662 43.781 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Pfam PF12344 Ultra-violet resistance protein B 556 598 1.2E-24 T 23-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SUPERFAMILY SSF52540 474 599 3.28E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SUPERFAMILY SSF52540 8 419 3.89E-139 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 10 660 0.0 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SUPERFAMILY SSF46600 617 661 1.31E-9 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SMART SM00487 14 430 3.9E-26 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:4.10.860.10 607 660 6.3E-14 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Pfam PF04851 Type III restriction enzyme, res subunit 17 142 7.5E-12 T 23-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Pfam PF02151 UvrB/uvrC motif 627 660 6.5E-7 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SUPERFAMILY SSF52540 38 85 3.28E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 PANTHER PTHR24029 4 660 0.0 T 23-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:3.40.50.300 393 414 9.1E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:3.40.50.300 10 94 9.1E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:3.40.50.300 283 343 9.1E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Pfam PF00271 Helicase conserved C-terminal domain 438 549 4.1E-19 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:3.30.2060.10 164 239 1.5E-11 T 23-04-2016 SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 Gene3D G3DSA:3.40.50.300 423 588 7.0E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05760 1b41f30817dbe48e2d5eeb6357a2ddc1 663 SMART SM00490 464 550 1.1E-19 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS09310 c2b3b98cb99a24241ddfe7d7faaf263b 186 Pfam PF03352 Methyladenine glycosylase 6 182 2.8E-74 T 23-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 SPYM18_RS09310 c2b3b98cb99a24241ddfe7d7faaf263b 186 SUPERFAMILY SSF48150 1 183 7.06E-75 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS09310 c2b3b98cb99a24241ddfe7d7faaf263b 186 PANTHER PTHR30037:SF4 1 184 7.3E-94 T 23-04-2016 SPYM18_RS09310 c2b3b98cb99a24241ddfe7d7faaf263b 186 Gene3D G3DSA:1.10.340.30 1 182 1.2E-77 T 23-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 SPYM18_RS09310 c2b3b98cb99a24241ddfe7d7faaf263b 186 PANTHER PTHR30037 1 184 7.3E-94 T 23-04-2016 SPYM18_RS07190 0e60e98c7be20f2100c993ddfc940ad4 74 Pfam PF13268 Protein of unknown function (DUF4059) 1 72 8.6E-30 T 23-04-2016 IPR025134 Protein of unknown function DUF4059 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Pfam PF02690 Na+/Pi-cotransporter 18 153 6.9E-47 T 23-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Pfam PF02690 Na+/Pi-cotransporter 147 260 1.8E-18 T 23-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Gene3D G3DSA:1.20.58.220 334 431 3.3E-13 T 23-04-2016 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Gene3D G3DSA:1.20.58.220 448 539 1.7E-18 T 23-04-2016 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 PANTHER PTHR10010 1 455 8.2E-111 T 23-04-2016 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 10 315 5.1E-71 T 23-04-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 PANTHER PTHR10010:SF26 1 455 8.2E-111 T 23-04-2016 SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Pfam PF01895 PhoU domain 453 537 1.5E-12 T 23-04-2016 IPR026022 PhoU domain SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 Pfam PF01895 PhoU domain 349 430 2.9E-9 T 23-04-2016 IPR026022 PhoU domain SPYM18_RS07330 7468e221aee0b92d3abb78e0505db549 543 SUPERFAMILY SSF109755 334 539 1.57E-42 T 23-04-2016 SPYM18_RS07430 870ecd0a7340680d3dca34d0fe2dca77 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 1.2E-13 T 23-04-2016 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 SPYM18_RS07430 870ecd0a7340680d3dca34d0fe2dca77 100 Gene3D G3DSA:3.30.1330.30 4 97 2.5E-20 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS07430 870ecd0a7340680d3dca34d0fe2dca77 100 SUPERFAMILY SSF55315 6 99 1.28E-23 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 Gene3D G3DSA:3.40.50.300 1 208 1.3E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 Pfam PF00271 Helicase conserved C-terminal domain 229 337 4.2E-25 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 SUPERFAMILY SSF52540 70 357 1.33E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 Pfam PF00270 DEAD/DEAH box helicase 25 191 3.8E-42 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 SMART SM00490 256 337 2.8E-27 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 1 435 50.679 T 23-04-2016 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 PANTHER PTHR24031 1 440 1.8E-209 T 23-04-2016 SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 Gene3D G3DSA:3.40.50.300 209 360 1.8E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 PANTHER PTHR24031:SF280 1 440 1.8E-209 T 23-04-2016 SPYM18_RS07205 89ecf5c7c1083ef64f15c856e808d608 447 SMART SM00487 20 220 1.2E-50 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS08255 bd4c764ea803ddbb3877571c196dfb6d 250 Pfam PF14506 CppA N-terminal 9 131 1.2E-64 T 23-04-2016 IPR032702 CppA, N-terminal SPYM18_RS08255 bd4c764ea803ddbb3877571c196dfb6d 250 Gene3D G3DSA:3.10.180.10 13 81 2.9E-6 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS08255 bd4c764ea803ddbb3877571c196dfb6d 250 Pfam PF14507 CppA C-terminal 146 248 1.2E-39 T 23-04-2016 IPR032703 CppA, C-terminal SPYM18_RS08255 bd4c764ea803ddbb3877571c196dfb6d 250 SUPERFAMILY SSF54593 12 184 2.49E-9 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS08255 bd4c764ea803ddbb3877571c196dfb6d 250 Gene3D G3DSA:3.10.180.40 82 192 5.3E-45 T 23-04-2016 SPYM18_RS06065 9eca62c8fe668107c02941be4541af90 235 SUPERFAMILY SSF53335 2 224 6.25E-49 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06065 9eca62c8fe668107c02941be4541af90 235 Pfam PF01596 O-methyltransferase 37 226 7.1E-29 T 23-04-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 SPYM18_RS06065 9eca62c8fe668107c02941be4541af90 235 Gene3D G3DSA:3.40.50.150 9 226 2.3E-60 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06065 9eca62c8fe668107c02941be4541af90 235 PANTHER PTHR10509:SF14 13 231 1.7E-71 T 23-04-2016 SPYM18_RS06065 9eca62c8fe668107c02941be4541af90 235 PANTHER PTHR10509 13 231 1.7E-71 T 23-04-2016 SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 TIGRFAM TIGR02134 transald_staph: transaldolase 2 237 1.1E-135 T 23-04-2016 IPR011861 Transaldolase, Staphylococcus-type SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 PANTHER PTHR10683:SF13 4 237 1.6E-94 T 23-04-2016 SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 Pfam PF00923 Transaldolase 10 230 5.1E-36 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 PANTHER PTHR10683 4 237 1.6E-94 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 SUPERFAMILY SSF51569 8 234 2.44E-48 T 23-04-2016 SPYM18_RS08690 a4c68a713e1fd8fb7e2a53a6eef0db00 242 Gene3D G3DSA:3.20.20.70 8 216 1.9E-36 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 SUPERFAMILY SSF55874 423 563 8.51E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Gene3D G3DSA:3.30.450.20 77 173 2.0E-12 T 23-04-2016 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Pfam PF00672 HAMP domain 285 351 2.0E-10 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 SMART SM00387 462 566 3.8E-6 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 467 564 2.3E-7 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 SUPERFAMILY SSF158472 304 353 5.62E-5 T 23-04-2016 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Gene3D G3DSA:3.30.450.20 174 282 6.2E-15 T 23-04-2016 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 PANTHER PTHR34220 1 570 7.6E-56 T 23-04-2016 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Pfam PF06580 Histidine kinase 369 447 8.6E-25 T 23-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 PANTHER PTHR34220:SF3 1 570 7.6E-56 T 23-04-2016 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Pfam PF02743 Cache domain 36 267 7.4E-29 T 23-04-2016 IPR033479 Double Cache domain 1 SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 Gene3D G3DSA:3.30.565.10 420 565 3.5E-18 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06765 30ce2f47430ff423ca993675c1b99a0e 577 SMART SM00304 304 356 5.7E-6 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 203 2.6E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 SUPERFAMILY SSF53850 237 505 1.7E-70 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 237 500 1.6E-64 T 23-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Gene3D G3DSA:3.40.190.120 347 444 1.0E-38 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 PANTHER PTHR30177 1 202 2.0E-211 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 PANTHER PTHR30177 269 506 2.0E-211 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 PANTHER PTHR30177:SF4 1 202 2.0E-211 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 PANTHER PTHR30177:SF4 269 506 2.0E-211 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Gene3D G3DSA:3.40.190.10 234 346 1.3E-57 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Gene3D G3DSA:3.40.190.10 456 506 1.3E-57 T 23-04-2016 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 SUPERFAMILY SSF161098 14 197 9.42E-38 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04720 608d0bd3359c3c469ea01445e199882f 508 Gene3D G3DSA:1.10.3720.10 9 199 5.5E-37 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05890 355e4ac217cc4e6576213e99e634ecf4 483 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 224 400 9.6E-27 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain SPYM18_RS05890 355e4ac217cc4e6576213e99e634ecf4 483 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 225 400 2.7E-50 T 23-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain SPYM18_RS05890 355e4ac217cc4e6576213e99e634ecf4 483 PANTHER PTHR33392:SF6 141 478 1.9E-70 T 23-04-2016 SPYM18_RS05890 355e4ac217cc4e6576213e99e634ecf4 483 PANTHER PTHR33392 141 478 1.9E-70 T 23-04-2016 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 Pfam PF16199 Radical_SAM C-terminal domain 212 295 8.1E-26 T 23-04-2016 IPR032432 Radical SAM, C-terminal extension SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 Pfam PF04055 Radical SAM superfamily 41 203 5.5E-12 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 SUPERFAMILY SSF102114 10 298 1.06E-44 T 23-04-2016 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 SMART SM00729 21 251 1.8E-28 T 23-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 4 304 5.1E-102 T 23-04-2016 IPR005911 Protein YhcC-like GO:0051536 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 PANTHER PTHR11135 1 302 6.1E-146 T 23-04-2016 SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 Gene3D G3DSA:3.80.30.20 19 252 8.7E-27 T 23-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe SPYM18_RS01945 2fd0924a086e19134f8b3dd7437d8f49 306 PANTHER PTHR11135:SF1 1 302 6.1E-146 T 23-04-2016 IPR005911 Protein YhcC-like GO:0051536 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 SUPERFAMILY SSF55681 156 496 1.28E-118 T 23-04-2016 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 497 6.1E-208 T 23-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PANTHER PTHR22594 1 497 3.0E-265 T 23-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 Gene3D G3DSA:2.40.50.140 10 149 7.1E-49 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 Gene3D G3DSA:3.30.930.10 151 494 9.5E-120 T 23-04-2016 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 Pfam PF00152 tRNA synthetases class II (D, K and N) 158 495 1.2E-77 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PANTHER PTHR22594:SF4 1 497 3.0E-265 T 23-04-2016 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 497 43.545 T 23-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 SUPERFAMILY SSF50249 8 149 2.69E-43 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 Pfam PF01336 OB-fold nucleic acid binding domain 65 138 4.4E-15 T 23-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 1.1E-37 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 1.1E-37 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 1.1E-37 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 1.1E-37 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS02840 be97bbc22fd33f41dabc5f58c00dcfa3 497 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 1.1E-37 T 23-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 PANTHER PTHR11017 424 635 2.5E-51 T 23-04-2016 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 PANTHER PTHR11017 673 685 2.5E-51 T 23-04-2016 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 PANTHER PTHR11017 226 358 2.5E-51 T 23-04-2016 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 Pfam PF13306 Leucine rich repeats (6 copies) 463 579 9.3E-21 T 23-04-2016 IPR026906 Leucine rich repeat 5 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 Pfam PF13306 Leucine rich repeats (6 copies) 236 359 3.9E-23 T 23-04-2016 IPR026906 Leucine rich repeat 5 SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 Gene3D G3DSA:3.80.10.10 276 348 7.3E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 Gene3D G3DSA:3.80.10.10 577 631 7.3E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 Gene3D G3DSA:3.80.10.10 442 522 7.3E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 SUPERFAMILY SSF52058 487 631 2.99E-5 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 SUPERFAMILY SSF52058 218 359 3.06E-6 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS03885 5582c560a1e7e98d2a64031c716b07db 1008 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 975 1007 0.0012 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 PANTHER PTHR22939:SF78 207 419 1.2E-63 T 23-04-2016 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 4 418 4.1E-75 T 23-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 Pfam PF02163 Peptidase family M50 6 405 4.6E-81 T 23-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 PANTHER PTHR22939 207 419 1.2E-63 T 23-04-2016 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 SUPERFAMILY SSF50156 176 274 4.86E-13 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 Pfam PF13180 PDZ domain 205 271 2.3E-8 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS08750 cd0693dcd0c7dbaf9b56f2f8c8184c1c 419 Gene3D G3DSA:2.30.42.10 168 273 1.8E-18 T 23-04-2016 IPR001478 PDZ domain GO:0005515 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 Pfam PF13649 Methyltransferase domain 42 136 4.8E-19 T 23-04-2016 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 PANTHER PTHR10108:SF872 5 168 2.7E-53 T 23-04-2016 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 PANTHER PTHR10108:SF872 194 246 2.7E-53 T 23-04-2016 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 SUPERFAMILY SSF53335 5 247 3.58E-52 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 PANTHER PTHR10108 5 168 2.7E-53 T 23-04-2016 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 PANTHER PTHR10108 194 246 2.7E-53 T 23-04-2016 SPYM18_RS01430 5c1815ec891fc311a34091d657200dd9 247 Gene3D G3DSA:3.40.50.150 2 247 7.8E-45 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF14520 Helix-hairpin-helix domain 432 486 1.8E-6 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 584 651 2.1E-14 T 23-04-2016 IPR001357 BRCT domain SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:2.40.50.140 308 379 2.7E-33 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SMART SM00292 579 651 7.8E-11 T 23-04-2016 IPR001357 BRCT domain SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:3.30.470.30 113 239 2.4E-45 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 109 138 - T 23-04-2016 IPR018239 NAD-dependent DNA ligase, active site SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 PIRSF PIRSF001604 1 652 3.5E-246 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 319 334 - T 23-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 306 3.9E-119 T 23-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SUPERFAMILY SSF56091 2 306 7.74E-115 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:1.10.150.20 490 570 1.1E-21 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF12826 Helix-hairpin-helix motif 496 556 1.0E-16 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SMART SM00278 530 549 130.0 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SMART SM00278 432 451 7.1 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SMART SM00278 466 485 0.29 T 23-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 8 647 8.0E-244 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:1.10.150.20 423 489 2.9E-27 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 310 386 7.3E-35 T 23-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 395 419 8.1E-9 T 23-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 PANTHER PTHR23389:SF9 1 507 1.8E-179 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 PANTHER PTHR23389 1 507 1.8E-179 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:1.10.287.610 2 64 1.8E-25 T 23-04-2016 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SUPERFAMILY SSF47781 391 571 4.45E-56 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SUPERFAMILY SSF50249 306 388 3.26E-28 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Hamap MF_01588 DNA ligase [ligA]. 1 652 48.843 T 23-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 Gene3D G3DSA:3.40.50.10190 578 651 1.3E-24 T 23-04-2016 IPR001357 BRCT domain SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SMART SM00532 2 434 1.0E-242 T 23-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 SPYM18_RS03500 8b3fe5c3b2359281846784e2dae6ab35 652 SUPERFAMILY SSF52113 580 651 3.27E-20 T 23-04-2016 IPR001357 BRCT domain SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 PANTHER PTHR21262 49 211 1.0E-28 T 23-04-2016 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 Gene3D G3DSA:1.10.287.860 163 213 4.6E-20 T 23-04-2016 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 Pfam PF04607 Region found in RelA / SpoT proteins 53 177 1.9E-33 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 SUPERFAMILY SSF81301 17 211 6.54E-46 T 23-04-2016 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 PANTHER PTHR21262:SF11 49 211 1.0E-28 T 23-04-2016 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 SMART SM00954 53 180 6.1E-38 T 23-04-2016 IPR007685 RelA/SpoT GO:0015969 SPYM18_RS04010 e3b3e6592f11e09f8f6134e82aa0433d 216 Gene3D G3DSA:3.30.460.10 17 160 5.0E-32 T 23-04-2016 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 37 161 1.3E-39 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 130 140 - T 23-04-2016 IPR020549 Endoribonuclease YbeY, conserved site SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 164 21.371 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 Pfam PF02130 Uncharacterized protein family UPF0054 14 159 1.1E-39 T 23-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 Gene3D G3DSA:3.40.390.30 6 164 9.6E-43 T 23-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 SUPERFAMILY SSF55486 2 164 6.84E-39 T 23-04-2016 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 PANTHER PTHR22881 37 80 1.3E-35 T 23-04-2016 SPYM18_RS02255 4e2c98d0005d6162fd8580e8648e87b3 165 PANTHER PTHR22881 96 164 1.3E-35 T 23-04-2016 SPYM18_RS01325 5b0019a093bc1cf64786328206e8c3df 472 PANTHER PTHR30508:SF1 17 472 1.1E-238 T 23-04-2016 SPYM18_RS01325 5b0019a093bc1cf64786328206e8c3df 472 PANTHER PTHR30508 17 472 1.1E-238 T 23-04-2016 SPYM18_RS01325 5b0019a093bc1cf64786328206e8c3df 472 Pfam PF01458 Uncharacterized protein family (UPF0051) 218 443 2.0E-74 T 23-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SPYM18_RS01325 5b0019a093bc1cf64786328206e8c3df 472 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 463 2.6E-220 T 23-04-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 SPYM18_RS01325 5b0019a093bc1cf64786328206e8c3df 472 SUPERFAMILY SSF101960 40 469 9.42E-138 T 23-04-2016 SPYM18_RS04480 b66af7c7309a76e5ec4d7c41fe6aa301 275 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 12 274 8.8E-82 T 23-04-2016 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 SPYM18_RS04480 b66af7c7309a76e5ec4d7c41fe6aa301 275 PANTHER PTHR32502:SF7 1 274 1.2E-79 T 23-04-2016 SPYM18_RS04480 b66af7c7309a76e5ec4d7c41fe6aa301 275 PANTHER PTHR32502 1 274 1.2E-79 T 23-04-2016 SPYM18_RS08310 0ee85fd4e91dc9936b135d22ee2839b7 195 SUPERFAMILY SSF53098 6 171 8.32E-30 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08310 0ee85fd4e91dc9936b135d22ee2839b7 195 Pfam PF00929 Exonuclease 8 162 1.5E-13 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS08310 0ee85fd4e91dc9936b135d22ee2839b7 195 Gene3D G3DSA:3.30.420.10 5 168 1.1E-29 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08310 0ee85fd4e91dc9936b135d22ee2839b7 195 PANTHER PTHR30231 6 171 6.3E-21 T 23-04-2016 SPYM18_RS08310 0ee85fd4e91dc9936b135d22ee2839b7 195 SMART SM00479 6 171 5.3E-17 T 23-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III SPYM18_RS09350 642c35ca30d661547e420cacf3347e64 102 Gene3D G3DSA:1.20.1440.50 1 78 4.7E-29 T 23-04-2016 IPR023130 Ta0600-like domain SPYM18_RS09350 642c35ca30d661547e420cacf3347e64 102 Pfam PF08951 Enterocin A Immunity 4 74 8.2E-12 T 23-04-2016 IPR015046 Enterocin A Immunity SPYM18_RS09350 642c35ca30d661547e420cacf3347e64 102 SUPERFAMILY SSF109797 2 98 3.66E-29 T 23-04-2016 SPYM18_RS06450 ca12ef2dbc0b1bc234e4cac3423104f2 128 Gene3D G3DSA:1.10.10.630 3 77 6.7E-28 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS06450 ca12ef2dbc0b1bc234e4cac3423104f2 128 Pfam PF07261 Replication initiation and membrane attachment 7 78 1.5E-25 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS06450 ca12ef2dbc0b1bc234e4cac3423104f2 128 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 6 77 8.7E-29 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS06450 ca12ef2dbc0b1bc234e4cac3423104f2 128 PANTHER PTHR41274 4 116 1.2E-21 T 23-04-2016 SPYM18_RS06450 ca12ef2dbc0b1bc234e4cac3423104f2 128 SUPERFAMILY SSF158499 6 72 9.15E-21 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS03110 ca12ef2dbc0b1bc234e4cac3423104f2 128 Gene3D G3DSA:1.10.10.630 3 77 6.7E-28 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS03110 ca12ef2dbc0b1bc234e4cac3423104f2 128 Pfam PF07261 Replication initiation and membrane attachment 7 78 1.5E-25 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS03110 ca12ef2dbc0b1bc234e4cac3423104f2 128 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 6 77 8.7E-29 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS03110 ca12ef2dbc0b1bc234e4cac3423104f2 128 PANTHER PTHR41274 4 116 1.2E-21 T 23-04-2016 SPYM18_RS03110 ca12ef2dbc0b1bc234e4cac3423104f2 128 SUPERFAMILY SSF158499 6 72 9.15E-21 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS00715 e832973522de78ff28c54c69285b4621 112 PANTHER PTHR10438:SF301 1 104 1.9E-39 T 23-04-2016 SPYM18_RS00715 e832973522de78ff28c54c69285b4621 112 PANTHER PTHR10438 1 104 1.9E-39 T 23-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 SPYM18_RS00715 e832973522de78ff28c54c69285b4621 112 Pfam PF00085 Thioredoxin 12 102 6.0E-16 T 23-04-2016 IPR013766 Thioredoxin domain GO:0045454 SPYM18_RS00715 e832973522de78ff28c54c69285b4621 112 Gene3D G3DSA:3.40.30.10 6 102 3.4E-20 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS00715 e832973522de78ff28c54c69285b4621 112 SUPERFAMILY SSF52833 4 101 3.37E-24 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS01630 562244cf78940da7d2ac5a6421d59e5d 161 Pfam PF07852 Protein of unknown function (DUF1642) 37 152 8.0E-28 T 23-04-2016 IPR012865 Protein of unknown function DUF1642 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 PANTHER PTHR30175:SF9 1 569 8.6E-243 T 23-04-2016 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 536 548 - T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 3 619 2.1E-254 T 23-04-2016 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 474 594 6.3E-44 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 Pfam PF02378 Phosphotransferase system, EIIC 109 385 1.5E-33 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 PANTHER PTHR30175 1 569 8.6E-243 T 23-04-2016 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 SUPERFAMILY SSF55604 6 79 1.57E-21 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 Gene3D G3DSA:2.70.70.10 469 618 1.6E-57 T 23-04-2016 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 473 596 9.3E-50 T 23-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 Pfam PF00367 phosphotransferase system, EIIB 8 40 2.6E-13 T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 Gene3D G3DSA:3.30.1360.60 1 79 5.2E-27 T 23-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 SUPERFAMILY SSF51261 469 616 8.2E-53 T 23-04-2016 IPR011055 Duplicated hybrid motif SPYM18_RS02755 01962fb8ccdd07bd9c3fd22425393456 620 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 23-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 Gene3D G3DSA:1.10.3370.10 6 433 5.9E-132 T 23-04-2016 IPR023201 SecY subunit domain SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 SUPERFAMILY SSF103491 5 421 6.41E-116 T 23-04-2016 IPR023201 SecY subunit domain SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PANTHER PTHR10906:SF2 3 430 5.3E-168 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 399 417 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 310 332 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PRINTS PR00303 Preprotein translocase SecY subunit signature 365 383 1.6E-89 T 23-04-2016 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PANTHER PTHR10906 3 430 5.3E-168 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 PIRSF PIRSF004557 1 433 1.3E-114 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 426 1.3E-133 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 Pfam PF00344 SecY translocase 69 412 4.1E-98 T 23-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 430 26.681 T 23-04-2016 IPR026593 Protein translocase subunit SecY SPYM18_RS00470 87e5fce9d2edd7afe51cd5079bc30902 434 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 23-04-2016 IPR030659 SecY conserved site SPYM18_RS06415 875fc38745df2f9a1ce27136ed48057d 170 Gene3D G3DSA:3.30.420.10 5 153 3.4E-7 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06415 875fc38745df2f9a1ce27136ed48057d 170 SUPERFAMILY SSF53098 4 158 1.02E-13 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06415 875fc38745df2f9a1ce27136ed48057d 170 Pfam PF07066 Lactococcus phage M3 protein 5 154 3.3E-6 T 23-04-2016 IPR009773 Lactococcus phage 712, M3 SPYM18_RS08900 0a5b214e22027f69a87edb65c84f3312 325 PANTHER PTHR30465 7 323 1.2E-102 T 23-04-2016 SPYM18_RS08900 0a5b214e22027f69a87edb65c84f3312 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 322 3.0E-43 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08900 0a5b214e22027f69a87edb65c84f3312 325 SUPERFAMILY SSF161098 95 305 9.29E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08900 0a5b214e22027f69a87edb65c84f3312 325 Gene3D G3DSA:1.10.3720.10 98 318 1.0E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08900 0a5b214e22027f69a87edb65c84f3312 325 PANTHER PTHR30465:SF24 7 323 1.2E-102 T 23-04-2016 SPYM18_RS02515 78e191b0d19d0d7af45bda80f8e049ef 261 PANTHER PTHR36833:SF1 1 261 3.7E-115 T 23-04-2016 SPYM18_RS02515 78e191b0d19d0d7af45bda80f8e049ef 261 Pfam PF06182 ABC-2 family transporter protein 35 260 3.8E-69 T 23-04-2016 IPR010390 Protein of unknown function DUF990 SPYM18_RS02515 78e191b0d19d0d7af45bda80f8e049ef 261 PANTHER PTHR36833 1 261 3.7E-115 T 23-04-2016 SPYM18_RS03215 05466353d2e8c4668fd2841ba8c16fdd 61 Gene3D G3DSA:3.30.920.30 1 61 6.8E-28 T 23-04-2016 SPYM18_RS03215 05466353d2e8c4668fd2841ba8c16fdd 61 SUPERFAMILY SSF54786 1 61 8.24E-18 T 23-04-2016 SPYM18_RS03215 05466353d2e8c4668fd2841ba8c16fdd 61 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 6 60 6.9E-19 T 23-04-2016 IPR012933 HicA mRNA interferase family GO:0003729 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 1.6E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 1.6E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 1.6E-11 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 Gene3D G3DSA:2.40.50.140 6 83 1.3E-34 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 Pfam PF00366 Ribosomal protein S17 11 78 1.5E-32 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 SUPERFAMILY SSF50249 6 83 2.83E-32 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 6 77 1.0E-35 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 4 82 24.519 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 4.7E-35 T 23-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 23-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00415 7d4ea866f5e74b1c68f882fd4467c986 86 PANTHER PTHR10744 3 85 5.1E-40 T 23-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08090 a74f4e79322a88ee780594e09b6be72f 326 Gene3D G3DSA:3.30.420.10 179 314 4.0E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08090 a74f4e79322a88ee780594e09b6be72f 326 PANTHER PTHR10948 4 323 1.1E-80 T 23-04-2016 SPYM18_RS08090 a74f4e79322a88ee780594e09b6be72f 326 Pfam PF13936 Helix-turn-helix domain 8 51 1.2E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS08090 a74f4e79322a88ee780594e09b6be72f 326 Gene3D G3DSA:1.10.10.60 7 46 5.8E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08090 a74f4e79322a88ee780594e09b6be72f 326 SUPERFAMILY SSF53098 176 314 6.07E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 PANTHER PTHR33393 5 247 5.8E-41 T 23-04-2016 SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 PANTHER PTHR33393:SF3 5 247 5.8E-41 T 23-04-2016 SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 SUPERFAMILY SSF63817 30 223 4.58E-43 T 23-04-2016 IPR023365 Sortase domain SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 Pfam PF04203 Sortase family 98 223 6.0E-26 T 23-04-2016 IPR005754 Sortase family SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 Gene3D G3DSA:2.40.260.10 86 225 4.4E-38 T 23-04-2016 IPR023365 Sortase domain SPYM18_RS04815 aadc63ba8e1f5bf3d104114f969e865d 249 TIGRFAM TIGR01076 sortase_fam: sortase 97 225 4.3E-17 T 23-04-2016 IPR005754 Sortase family SPYM18_RS03960 aa94edcade209344e1036c10f4843ed2 69 Gene3D G3DSA:3.10.20.120 1 69 6.2E-18 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS03960 aa94edcade209344e1036c10f4843ed2 69 SUPERFAMILY SSF54334 1 69 8.64E-18 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS03960 aa94edcade209344e1036c10f4843ed2 69 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 2 67 3.5E-17 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 PANTHER PTHR32438:SF5 2 497 5.7E-127 T 23-04-2016 SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 Pfam PF02446 4-alpha-glucanotransferase 10 473 1.0E-149 T 23-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 Gene3D G3DSA:3.20.20.80 2 496 9.3E-168 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 2 495 2.6E-98 T 23-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 SUPERFAMILY SSF51445 3 495 6.9E-159 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS05695 0fc2a87b2203cc66a12d41252c38d264 497 PANTHER PTHR32438 2 497 5.7E-127 T 23-04-2016 SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 Gene3D G3DSA:3.40.50.300 101 289 2.1E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 Pfam PF07319 Primosomal protein DnaI N-terminus 1 90 2.9E-24 T 23-04-2016 IPR009928 Primosomal DnaI, N-terminal SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 PANTHER PTHR30050 27 300 1.4E-91 T 23-04-2016 SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 PANTHER PTHR30050:SF8 27 300 1.4E-91 T 23-04-2016 SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 SUPERFAMILY SSF52540 116 266 4.01E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01525 eda206b4efbac618e7d0549d25cbe390 300 Pfam PF01695 IstB-like ATP binding protein 150 264 5.8E-13 T 23-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 55 1.0E-4 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 SUPERFAMILY SSF46689 5 65 3.08E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 Gene3D G3DSA:1.10.357.10 6 173 6.0E-13 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 PANTHER PTHR30328 7 153 7.5E-15 T 23-04-2016 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 PANTHER PTHR30328:SF20 7 153 7.5E-15 T 23-04-2016 SPYM18_RS02525 d495dc74c044f1af382faa218bdea7d3 178 TIGRFAM TIGR02366 DHAK_reg: probable dihydroxyacetone kinase regulator 4 177 1.4E-76 T 23-04-2016 IPR012738 Transcription regulator DhaS SPYM18_RS02260 cd20f7d6f847a4f44fab7bb942001bff 135 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 77 88 - T 23-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 SPYM18_RS02260 cd20f7d6f847a4f44fab7bb942001bff 135 PANTHER PTHR34299 4 134 1.2E-32 T 23-04-2016 SPYM18_RS02260 cd20f7d6f847a4f44fab7bb942001bff 135 Pfam PF01219 Prokaryotic diacylglycerol kinase 24 125 2.9E-32 T 23-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 SPYM18_RS02260 cd20f7d6f847a4f44fab7bb942001bff 135 Gene3D G3DSA:1.10.3830.10 10 130 5.9E-41 T 23-04-2016 SPYM18_RS02260 cd20f7d6f847a4f44fab7bb942001bff 135 PANTHER PTHR34299:SF1 4 134 1.2E-32 T 23-04-2016 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Gene3D G3DSA:2.40.50.140 298 360 7.6E-14 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 SUPERFAMILY SSF50331 248 376 1.31E-28 T 23-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Gene3D G3DSA:2.40.50.100 251 297 2.9E-23 T 23-04-2016 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Gene3D G3DSA:2.40.50.100 362 377 2.9E-23 T 23-04-2016 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 PANTHER PTHR24220 5 320 2.1E-166 T 23-04-2016 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Pfam PF00005 ABC transporter 22 163 4.5E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 SUPERFAMILY SSF52540 4 256 3.25E-80 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 SMART SM00382 30 213 4.3E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 PANTHER PTHR24220:SF151 5 320 2.1E-166 T 23-04-2016 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Pfam PF03459 TOBE domain 311 366 6.1E-10 T 23-04-2016 IPR005116 Transport-associated OB, type 1 SPYM18_RS08785 576859c57a9397bb1a3acc9d2d2d6758 377 Gene3D G3DSA:3.40.50.300 4 246 3.0E-72 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 SUPERFAMILY SSF52540 5 268 2.83E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 Gene3D G3DSA:3.30.450.90 2 109 3.5E-16 T 23-04-2016 SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 Gene3D G3DSA:3.40.50.300 130 268 4.7E-48 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 Pfam PF00437 Type II/IV secretion system protein 14 266 1.3E-40 T 23-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 PANTHER PTHR30258 5 267 1.7E-66 T 23-04-2016 SPYM18_RS00645 4628cae2cd485d6d656c8a88aa7d7337 312 PANTHER PTHR30258:SF2 5 267 1.7E-66 T 23-04-2016 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 PANTHER PTHR10724:SF1 1 709 2.7E-304 T 23-04-2016 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SUPERFAMILY SSF53098 305 453 2.09E-48 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Pfam PF09371 Tex-like protein N-terminal domain 9 189 2.4E-60 T 23-04-2016 IPR018974 Tex-like protein, N-terminal SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SMART SM00732 309 408 1.3E-38 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:2.40.50.140 619 705 1.2E-26 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SUPERFAMILY SSF158832 3 303 2.22E-97 T 23-04-2016 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:1.10.3500.10 110 305 2.7E-83 T 23-04-2016 IPR023323 Tex-like domain SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:1.10.3500.10 435 482 2.7E-83 T 23-04-2016 IPR023323 Tex-like domain SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SUPERFAMILY SSF50249 620 706 4.25E-23 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:1.10.10.650 1 109 5.3E-38 T 23-04-2016 IPR023319 Tex-like protein, HTH domain SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Pfam PF00575 S1 RNA binding domain 632 703 4.8E-16 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Pfam PF16921 Tex protein YqgF-like domain 309 435 1.8E-53 T 23-04-2016 IPR032639 Tex protein, YqgF-like domain SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:1.10.150.310 483 614 5.4E-44 T 23-04-2016 IPR023097 Tex RuvX-like domain SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SUPERFAMILY SSF47781 454 541 6.82E-25 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 PANTHER PTHR10724 1 709 2.7E-304 T 23-04-2016 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Pfam PF12836 Helix-hairpin-helix motif 475 539 3.4E-26 T 23-04-2016 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SUPERFAMILY SSF47781 544 616 5.67E-17 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 SMART SM00316 633 704 1.9E-22 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS02780 d63d2db5ef2ad3fb2b56c6048559a481 710 Gene3D G3DSA:3.30.420.140 309 434 6.5E-50 T 23-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Gene3D G3DSA:3.40.50.970 6 326 2.4E-125 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Gene3D G3DSA:3.40.50.970 327 533 1.9E-73 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 SUPERFAMILY SSF52922 533 660 2.22E-38 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 SMART SM00861 352 523 4.4E-63 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 PANTHER PTHR11624:SF1 3 315 0.0 T 23-04-2016 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 PANTHER PTHR11624:SF1 339 656 0.0 T 23-04-2016 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 660 1.9E-277 T 23-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 SUPERFAMILY SSF52518 343 524 3.79E-64 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 336 2.9E-148 T 23-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 ProSitePatterns PS00802 Transketolase signature 2. 465 481 - T 23-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Pfam PF02779 Transketolase, pyrimidine binding domain 352 522 5.5E-44 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Pfam PF02780 Transketolase, C-terminal domain 552 652 1.1E-10 T 23-04-2016 IPR033248 Transketolase, C-terminal domain SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 PANTHER PTHR11624 3 315 0.0 T 23-04-2016 IPR033247 Transketolase family SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 PANTHER PTHR11624 339 656 0.0 T 23-04-2016 IPR033247 Transketolase family SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 Gene3D G3DSA:3.40.50.920 537 659 2.9E-43 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPYM18_RS07260 9b80fd53a3fc3496bb7f9599b7c65503 661 SUPERFAMILY SSF52518 6 326 5.47E-118 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 Gene3D G3DSA:3.40.50.2000 3 422 1.9E-136 T 23-04-2016 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 Gene3D G3DSA:3.40.50.2000 423 738 2.2E-112 T 23-04-2016 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 596 608 - T 23-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 3 752 8.2E-264 T 23-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 PANTHER PTHR11468 3 752 5.0E-276 T 23-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 PIRSF PIRSF000460 1 754 4.7E-189 T 23-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 SUPERFAMILY SSF53756 3 752 1.57E-247 T 23-04-2016 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 PANTHER PTHR11468:SF3 3 752 5.0E-276 T 23-04-2016 SPYM18_RS05690 9c51756e8cad8dcc111d99154ba5f286 754 Pfam PF00343 Carbohydrate phosphorylase 79 752 1.4E-251 T 23-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 PANTHER PTHR11374 1 370 1.6E-137 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 PIRSF PIRSF500134 1 383 1.6E-93 T 23-04-2016 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00500+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|UniPathway: UPA00038 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 165 3.7E-31 T 23-04-2016 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 PIRSF PIRSF000124 1 385 1.6E-134 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Gene3D G3DSA:3.40.50.720 1 202 6.6E-51 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 SUPERFAMILY SSF51735 1 183 2.21E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Gene3D G3DSA:1.10.1040.10 203 280 8.4E-30 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 298 375 2.1E-9 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 377 1.7E-109 T 23-04-2016 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Gene3D G3DSA:3.40.50.720 281 385 2.7E-37 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 SUPERFAMILY SSF48179 189 283 7.14E-27 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 SUPERFAMILY SSF52413 283 383 3.79E-21 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 PANTHER PTHR11374:SF17 1 370 1.6E-137 T 23-04-2016 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 189 277 3.0E-24 T 23-04-2016 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 SPYM18_RS02635 38b39fcab44dbd5a32c3f9289e96e209 385 SMART SM00984 297 384 1.2E-8 T 23-04-2016 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 PANTHER PTHR11136:SF0 7 420 5.3E-116 T 23-04-2016 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 Gene3D G3DSA:3.90.190.20 294 413 8.5E-22 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 409 5.4E-130 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 PANTHER PTHR11136 7 420 5.3E-116 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 Gene3D G3DSA:3.40.1190.10 4 293 6.3E-87 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 SUPERFAMILY SSF53623 2 292 1.83E-83 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 SUPERFAMILY SSF53244 294 410 1.06E-19 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 PIRSF PIRSF001563 1 415 5.1E-120 T 23-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 Pfam PF02875 Mur ligase family, glutamate ligase domain 292 339 5.6E-6 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS03770 9231f2a870031b81824a1319cc9e8c82 422 Pfam PF08245 Mur ligase middle domain 44 267 1.5E-11 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 Gene3D G3DSA:3.90.1550.10 23 268 2.2E-67 T 23-04-2016 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 SUPERFAMILY SSF55681 24 260 1.39E-59 T 23-04-2016 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 PANTHER PTHR12561 51 237 2.6E-46 T 23-04-2016 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 6 277 32.995 T 23-04-2016 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20|MetaCyc: PWY-6987|UniPathway: UPA00538 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 PANTHER PTHR12561:SF6 51 237 2.6E-46 T 23-04-2016 SPYM18_RS05065 56c49ba8b848fd3f54698b52d9b9d620 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 73 181 9.1E-12 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPYM18_RS08790 d391e8d5efa00d3d5a27a1c132866097 282 SUPERFAMILY SSF46689 212 258 4.26E-7 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08790 d391e8d5efa00d3d5a27a1c132866097 282 Gene3D G3DSA:1.10.10.60 230 258 2.4E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08790 d391e8d5efa00d3d5a27a1c132866097 282 Pfam PF13556 PucR C-terminal helix-turn-helix domain 227 278 4.0E-10 T 23-04-2016 IPR025736 PucR C-terminal helix-turn-helix domain SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 PRINTS PR01576 Peptide deformylase signature 30 59 2.0E-12 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 PRINTS PR01576 Peptide deformylase signature 113 136 2.0E-12 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 PRINTS PR01576 Peptide deformylase signature 83 94 2.0E-12 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 PANTHER PTHR10458 28 136 1.6E-20 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 Gene3D G3DSA:3.90.45.10 2 136 2.9E-32 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 Pfam PF01327 Polypeptide deformylase 10 136 3.8E-24 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 SUPERFAMILY SSF56420 11 136 2.88E-33 T 23-04-2016 IPR023635 Peptide deformylase SPYM18_RS04000 e0e489200e161f1f25441fff3173f8ae 136 PIRSF PIRSF004749 2 136 1.8E-27 T 23-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 SPYM18_RS01285 e511974a099538aae41f0ed2e0e213ef 641 Pfam PF09972 Predicted membrane protein (DUF2207) 27 571 1.9E-80 T 23-04-2016 IPR018702 Protein of unknown function DUF2207, membrane SPYM18_RS05095 10c5e8d4ad6f217acf498f2fa93f14a3 354 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 333 4.5E-39 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPYM18_RS05095 10c5e8d4ad6f217acf498f2fa93f14a3 354 PANTHER PTHR32196:SF30 10 348 1.9E-93 T 23-04-2016 SPYM18_RS05095 10c5e8d4ad6f217acf498f2fa93f14a3 354 PANTHER PTHR32196 10 348 1.9E-93 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00365 615 636 74.0 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00365 639 665 23.0 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00365 687 712 290.0 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00365 734 752 210.0 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00365 758 779 730.0 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SUPERFAMILY SSF52058 551 802 1.11E-46 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Gene3D G3DSA:3.80.10.10 550 655 1.1E-24 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF13855 Leucine rich repeat 641 700 7.6E-12 T 23-04-2016 IPR001611 Leucine-rich repeat GO:0005515 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF13855 Leucine rich repeat 712 771 3.7E-9 T 23-04-2016 IPR001611 Leucine-rich repeat GO:0005515 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF13855 Leucine rich repeat 569 626 1.4E-13 T 23-04-2016 IPR001611 Leucine-rich repeat GO:0005515 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SUPERFAMILY SSF158911 372 501 2.35E-12 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF07550 Protein of unknown function (DUF1533) 204 269 1.0E-17 T 23-04-2016 IPR011432 Domain of unknown function DUF1533 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF07550 Protein of unknown function (DUF1533) 62 123 1.1E-12 T 23-04-2016 IPR011432 Domain of unknown function DUF1533 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00725 369 501 2.2E-38 T 23-04-2016 IPR006635 NEAT domain SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00725 976 1129 8.3E-29 T 23-04-2016 IPR006635 NEAT domain SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF05031 Iron Transport-associated domain 367 496 3.1E-18 T 23-04-2016 IPR006635 NEAT domain SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Pfam PF05031 Iron Transport-associated domain 975 1126 9.3E-22 T 23-04-2016 IPR006635 NEAT domain SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 710 733 72.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 568 590 4.2 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 591 614 0.057 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 734 757 4.5E-4 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 687 709 26.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 639 662 2.4 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 760 781 260.0 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 663 686 4.3 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SMART SM00369 616 638 6.8 T 23-04-2016 IPR003591 Leucine-rich repeat, typical subtype SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 ProSitePatterns PS00018 EF-hand calcium-binding domain. 532 544 - T 23-04-2016 IPR018247 EF-Hand 1, calcium-binding site SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 SUPERFAMILY SSF158911 978 1025 5.62E-5 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 Gene3D G3DSA:3.80.10.10 656 804 3.1E-31 T 23-04-2016 IPR032675 Leucine-rich repeat domain, L domain-like SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 PANTHER PTHR24365 550 815 2.3E-47 T 23-04-2016 SPYM18_RS08065 e597802496b48a2715ef9643b0709b0e 1275 PANTHER PTHR24365 840 859 2.3E-47 T 23-04-2016 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 Hamap MF_00258 Glutamate racemase [murI]. 4 256 39.518 T 23-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 254 1.3E-79 T 23-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 Gene3D G3DSA:3.40.50.1860 2 172 6.8E-56 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 SUPERFAMILY SSF53681 5 106 3.92E-34 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 PANTHER PTHR21198:SF2 1 264 2.0E-111 T 23-04-2016 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 PANTHER PTHR21198 1 264 2.0E-111 T 23-04-2016 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 23-04-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 213 4.1E-34 T 23-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01875 dd316a740ac9d13fc8b48810b099b164 264 SUPERFAMILY SSF53681 110 262 3.53E-41 T 23-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS05550 3bc4c6654f5713ce8fba44eec33166e6 210 Pfam PF02384 N-6 DNA Methylase 49 160 2.7E-8 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPYM18_RS05550 3bc4c6654f5713ce8fba44eec33166e6 210 SUPERFAMILY SSF53335 39 157 1.63E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 SUPERFAMILY SSF75217 11 181 7.85E-41 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 PANTHER PTHR12029:SF31 19 174 7.8E-68 T 23-04-2016 SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 Pfam PF00588 SpoU rRNA Methylase family 19 159 3.6E-34 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 Gene3D G3DSA:3.40.1280.10 5 180 1.6E-63 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 18 168 34.337 T 23-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 PIRSF PIRSF029256 17 171 3.9E-60 T 23-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 SPYM18_RS01925 2b2cb665044387e2c89a747186392f58 182 PANTHER PTHR12029 19 174 7.8E-68 T 23-04-2016 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 PIRSF PIRSF035805 1 189 8.7E-60 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 Pfam PF00265 Thymidine kinase 3 184 1.3E-49 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 PANTHER PTHR11441 1 189 1.1E-67 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 Gene3D G3DSA:3.30.60.20 140 188 8.1E-21 T 23-04-2016 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 23-04-2016 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 SUPERFAMILY SSF52540 2 140 1.32E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 SUPERFAMILY SSF57716 140 187 3.61E-17 T 23-04-2016 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 34.251 T 23-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 SPYM18_RS04750 f02fb3371f0a298ba07f7c789e2d783a 189 Gene3D G3DSA:3.40.50.300 8 106 2.9E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 3 83 3.0E-26 T 23-04-2016 IPR011279 Chorismate mutase, Gram-positive SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 SMART SM00830 7 86 1.8E-24 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 Gene3D G3DSA:1.20.59.10 1 84 1.3E-24 T 23-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 Pfam PF01817 Chorismate mutase type II 7 83 1.4E-20 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 SUPERFAMILY SSF48600 2 87 5.95E-22 T 23-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 SPYM18_RS03395 88a6b6aed4c30cb9b030f217dda8434d 94 PANTHER PTHR38041 1 85 6.9E-14 T 23-04-2016 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 323 33.596 T 23-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 PANTHER PTHR10578:SF3 15 210 1.4E-101 T 23-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 PANTHER PTHR10578:SF3 226 327 1.4E-101 T 23-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 Pfam PF01070 FMN-dependent dehydrogenase 19 92 6.6E-7 T 23-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 Pfam PF01070 FMN-dependent dehydrogenase 158 315 3.2E-18 T 23-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 Gene3D G3DSA:3.20.20.70 19 320 2.7E-111 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 PIRSF PIRSF003314 1 329 1.4E-107 T 23-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 PANTHER PTHR10578 15 210 1.4E-101 T 23-04-2016 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 PANTHER PTHR10578 226 327 1.4E-101 T 23-04-2016 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 SUPERFAMILY SSF51395 19 324 2.4E-74 T 23-04-2016 SPYM18_RS04040 f023bb4b7107ea8a0fff98999077b3a7 329 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 3 322 1.5E-118 T 23-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 PIRSF PIRSF002122 1 156 5.2E-56 T 23-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.4E-68 T 23-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.29 T 23-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.7E-65 T 23-04-2016 IPR023798 Ribosomal protein S7 domain SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 SUPERFAMILY SSF47973 1 149 3.27E-59 T 23-04-2016 IPR023798 Ribosomal protein S7 domain SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 23-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 Gene3D G3DSA:1.10.455.10 7 156 2.7E-65 T 23-04-2016 IPR023798 Ribosomal protein S7 domain SPYM18_RS01260 554202b6b11f0e508142239d09f3c50d 156 PANTHER PTHR11205 1 156 4.6E-86 T 23-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 PANTHER PTHR30471:SF3 1 225 1.8E-90 T 23-04-2016 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 TIGRFAM TIGR00608 radc: DNA repair protein RadC 12 225 6.5E-69 T 23-04-2016 IPR001405 RadC protein SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 Pfam PF04002 RadC-like JAB domain 107 222 1.2E-38 T 23-04-2016 IPR025657 RadC-like JAB domain SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 Gene3D G3DSA:1.10.150.20 51 85 9.2E-4 T 23-04-2016 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 Gene3D G3DSA:3.40.140.10 106 224 3.3E-41 T 23-04-2016 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 SUPERFAMILY SSF47781 16 88 6.35E-6 T 23-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 PANTHER PTHR30471 1 225 1.8E-90 T 23-04-2016 SPYM18_RS04650 dcd0abed3c7e50c363c45d53002e6144 226 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 23-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site SPYM18_RS00790 e2e61966e03968e9a50bab1a522d5539 468 PANTHER PTHR41983 1 468 5.6E-74 T 23-04-2016 SPYM18_RS00790 e2e61966e03968e9a50bab1a522d5539 468 Pfam PF02667 Short chain fatty acid transporter 18 466 4.5E-80 T 23-04-2016 IPR006160 Short chain fatty acid transporter AtoE SPYM18_RS00820 0bbc637537707bf1e1c962ecc1ea9718 121 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 116 2.1E-32 T 23-04-2016 IPR006056 RidA family SPYM18_RS00820 0bbc637537707bf1e1c962ecc1ea9718 121 SUPERFAMILY SSF55298 3 119 8.64E-36 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPYM18_RS00820 0bbc637537707bf1e1c962ecc1ea9718 121 Pfam PF01042 Endoribonuclease L-PSP 3 117 8.6E-32 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family SPYM18_RS00820 0bbc637537707bf1e1c962ecc1ea9718 121 PANTHER PTHR11803 5 121 6.2E-37 T 23-04-2016 IPR006175 YjgF/YER057c/UK114 family SPYM18_RS00820 0bbc637537707bf1e1c962ecc1ea9718 121 Gene3D G3DSA:3.30.1330.40 3 116 4.7E-36 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPYM18_RS02615 b543d5cfcac1aad2ad40693b4299b3ff 328 Gene3D G3DSA:3.40.50.720 60 171 9.5E-7 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02615 b543d5cfcac1aad2ad40693b4299b3ff 328 SUPERFAMILY SSF51735 8 135 7.09E-13 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02615 b543d5cfcac1aad2ad40693b4299b3ff 328 Gene3D G3DSA:3.40.50.720 8 59 5.5E-4 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 5.5E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 5.5E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 5.5E-8 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 Pfam PF01047 MarR family 36 93 1.2E-12 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 PANTHER PTHR33164:SF4 11 138 5.2E-24 T 23-04-2016 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 Gene3D G3DSA:1.10.10.10 10 141 3.4E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 PANTHER PTHR33164 11 138 5.2E-24 T 23-04-2016 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 SMART SM00347 29 129 4.6E-22 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS08735 37f9ba510a63afd9b0aa3fe34a1507aa 142 SUPERFAMILY SSF46785 12 141 1.29E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 Gene3D G3DSA:3.30.420.40 2 254 1.1E-107 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 Hamap MF_00186 Glycerol kinase [glpK]. 4 498 56.132 T 23-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 495 1.9E-221 T 23-04-2016 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 Gene3D G3DSA:3.30.420.40 256 496 1.8E-94 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 1.2E-86 T 23-04-2016 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 PANTHER PTHR10196 1 506 4.9E-250 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 136 148 - T 23-04-2016 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 PANTHER PTHR10196:SF9 1 506 4.9E-250 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 SUPERFAMILY SSF53067 256 494 7.13E-78 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 SUPERFAMILY SSF53067 5 255 3.89E-97 T 23-04-2016 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 451 1.4E-56 T 23-04-2016 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 SPYM18_RS07290 5ffd546c0b294a8bdd0ae0895a063b85 508 PIRSF PIRSF000538 4 502 4.4E-169 T 23-04-2016 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|UniPathway: UPA00618 SPYM18_RS04765 2074a99c9842bef73cd66d23d884aa2d 196 SUPERFAMILY SSF55821 2 192 3.66E-53 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain SPYM18_RS04765 2074a99c9842bef73cd66d23d884aa2d 196 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 3 186 6.3E-48 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 SPYM18_RS04765 2074a99c9842bef73cd66d23d884aa2d 196 PANTHER PTHR17490 2 189 9.4E-57 T 23-04-2016 SPYM18_RS04765 2074a99c9842bef73cd66d23d884aa2d 196 Gene3D G3DSA:3.90.870.10 3 187 2.6E-57 T 23-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain SPYM18_RS04765 2074a99c9842bef73cd66d23d884aa2d 196 Pfam PF01300 Telomere recombination 7 180 1.1E-43 T 23-04-2016 IPR006070 YrdC-like domain GO:0003725 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 Pfam PF02872 5'-nucleotidase, C-terminal domain 368 530 8.5E-33 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 SUPERFAMILY SSF55816 366 553 1.57E-39 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 ProSitePatterns PS00786 5'-nucleotidase signature 2. 119 130 - T 23-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 Pfam PF00149 Calcineurin-like phosphoesterase 34 293 8.7E-8 T 23-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 Gene3D G3DSA:3.90.780.10 368 564 6.1E-40 T 23-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 Gene3D G3DSA:3.60.21.10 26 363 1.1E-62 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PRINTS PR01607 Apyrase family signature 429 452 3.8E-14 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PRINTS PR01607 Apyrase family signature 30 48 3.8E-14 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PRINTS PR01607 Apyrase family signature 275 298 3.8E-14 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PRINTS PR01607 Apyrase family signature 504 523 3.8E-14 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575 159 549 5.3E-103 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575 627 636 5.3E-103 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575 1 142 5.3E-103 T 23-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 SUPERFAMILY SSF56300 27 363 1.45E-55 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575:SF7 159 549 5.3E-103 T 23-04-2016 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575:SF7 627 636 5.3E-103 T 23-04-2016 SPYM18_RS04005 b9b43722179a3da854332e71a1e39710 670 PANTHER PTHR11575:SF7 1 142 5.3E-103 T 23-04-2016 SPYM18_RS07550 0379efc36ba3e0b569c779633270f0f8 142 Pfam PF07761 Protein of unknown function (DUF1617) 1 140 2.9E-74 T 23-04-2016 IPR011675 Protein of unknown function DUF1617 SPYM18_RS04915 130ad519c0f64c4455cd0d3f98eedec5 373 PANTHER PTHR35806 5 373 9.3E-161 T 23-04-2016 SPYM18_RS04915 130ad519c0f64c4455cd0d3f98eedec5 373 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 15 371 7.4E-154 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS04915 130ad519c0f64c4455cd0d3f98eedec5 373 PIRSF PIRSF015658 2 373 2.4E-159 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS04915 130ad519c0f64c4455cd0d3f98eedec5 373 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 15 366 2.3E-131 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS09290 0b6fb3d618c3fb9ec802bfb376de130f 89 PIRSF PIRSF037258 1 87 2.8E-43 T 23-04-2016 IPR009309 Uncharacterised protein family UPF0297 SPYM18_RS09290 0b6fb3d618c3fb9ec802bfb376de130f 89 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 7.7E-36 T 23-04-2016 IPR009309 Uncharacterised protein family UPF0297 SPYM18_RS09290 0b6fb3d618c3fb9ec802bfb376de130f 89 Hamap MF_01507 UPF0297 protein . 1 84 27.191 T 23-04-2016 IPR009309 Uncharacterised protein family UPF0297 SPYM18_RS09290 0b6fb3d618c3fb9ec802bfb376de130f 89 PANTHER PTHR40067 2 88 1.3E-43 T 23-04-2016 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 227 239 5.7E-8 T 23-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 19 35 5.7E-8 T 23-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 44 58 5.7E-8 T 23-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 65 78 5.7E-8 T 23-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 19 255 1.4E-10 T 23-04-2016 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 Gene3D G3DSA:3.40.50.150 214 292 7.2E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 Gene3D G3DSA:3.40.50.150 17 76 7.2E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS03205 0dbd9bdd2ab97b0f4e0b833eb714c034 309 SUPERFAMILY SSF53335 17 305 3.08E-23 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 Gene3D G3DSA:3.40.1130.10 3 196 7.8E-22 T 23-04-2016 SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 PANTHER PTHR10434:SF21 2 196 9.4E-54 T 23-04-2016 SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 SMART SM00563 36 146 1.9E-22 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 Pfam PF01553 Acyltransferase 25 143 2.7E-16 T 23-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 PANTHER PTHR10434 2 196 9.4E-54 T 23-04-2016 SPYM18_RS06135 11e6fdfbb96c326b0eb805a40a8fc6c8 246 SUPERFAMILY SSF69593 2 215 2.62E-57 T 23-04-2016 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 SUPERFAMILY SSF53901 3 166 6.37E-37 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 47 152 6.3E-5 T 23-04-2016 IPR001099 Chalcone/stilbene synthase, N-terminal SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 Gene3D G3DSA:3.40.47.10 1 250 4.1E-81 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 2.3E-160 T 23-04-2016 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 PANTHER PTHR11877 3 391 2.4E-80 T 23-04-2016 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 SUPERFAMILY SSF53901 168 386 6.25E-65 T 23-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 181 252 8.4E-8 T 23-04-2016 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00058 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 264 349 1.3E-12 T 23-04-2016 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00058 SPYM18_RS04050 1a8e4e2d6a0f124a6b98bbc7d3b9875e 391 PANTHER PTHR11877:SF26 3 391 2.4E-80 T 23-04-2016 SPYM18_RS07460 641305cc749a990c574ec413a1b155c9 263 SUPERFAMILY SSF56112 14 222 7.42E-34 T 23-04-2016 IPR011009 Protein kinase-like domain SPYM18_RS07460 641305cc749a990c574ec413a1b155c9 263 PANTHER PTHR40086 7 262 6.2E-56 T 23-04-2016 SPYM18_RS07460 641305cc749a990c574ec413a1b155c9 263 Pfam PF01636 Phosphotransferase enzyme family 41 211 2.6E-14 T 23-04-2016 IPR002575 Aminoglycoside phosphotransferase SPYM18_RS07460 641305cc749a990c574ec413a1b155c9 263 Gene3D G3DSA:3.90.1200.10 69 210 8.8E-16 T 23-04-2016 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SUPERFAMILY SSF48452 111 234 4.17E-8 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Gene3D G3DSA:3.40.50.300 364 423 3.3E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Gene3D G3DSA:3.40.50.300 244 310 3.3E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SMART SM00028 874 907 28.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SMART SM00028 834 867 49.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SMART SM00028 789 822 210.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SMART SM00028 709 742 260.0 T 23-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Pfam PF13191 AAA ATPase domain 249 413 3.6E-15 T 23-04-2016 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SUPERFAMILY SSF52540 246 499 3.48E-17 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Gene3D G3DSA:1.25.40.10 785 949 5.5E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Gene3D G3DSA:1.25.40.10 716 744 5.5E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Gene3D G3DSA:1.25.40.10 472 482 5.5E-11 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SMART SM01043 98 230 2.2E-25 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 SUPERFAMILY SSF48452 782 960 9.49E-12 T 23-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 Pfam PF03704 Bacterial transcriptional activator domain 110 229 2.7E-12 T 23-04-2016 IPR005158 Bacterial transcriptional activator domain SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 PANTHER PTHR16305 243 708 2.2E-18 T 23-04-2016 SPYM18_RS09205 628c39c04a7cdb02049c12f8da50b3d1 1024 PANTHER PTHR16305 918 963 2.2E-18 T 23-04-2016 SPYM18_RS09355 bb5415419f349ca045a33530cb93e90e 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 224 277 1.3E-17 T 23-04-2016 IPR019264 Domain of unknown function DUF2179 SPYM18_RS09355 bb5415419f349ca045a33530cb93e90e 290 PANTHER PTHR33545 1 287 1.7E-97 T 23-04-2016 SPYM18_RS09355 bb5415419f349ca045a33530cb93e90e 290 PANTHER PTHR33545:SF7 1 287 1.7E-97 T 23-04-2016 SPYM18_RS09355 bb5415419f349ca045a33530cb93e90e 290 PIRSF PIRSF006483 1 285 1.6E-75 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS09355 bb5415419f349ca045a33530cb93e90e 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 13 218 5.6E-61 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS02510 e25bd04f66aa11e78dc964d34c32f0d3 272 PANTHER PTHR36832 1 272 1.1E-88 T 23-04-2016 SPYM18_RS02510 e25bd04f66aa11e78dc964d34c32f0d3 272 Pfam PF06182 ABC-2 family transporter protein 38 271 1.9E-25 T 23-04-2016 IPR010390 Protein of unknown function DUF990 SPYM18_RS02510 e25bd04f66aa11e78dc964d34c32f0d3 272 PANTHER PTHR36832:SF1 1 272 1.1E-88 T 23-04-2016 SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 SUPERFAMILY SSF116726 134 217 1.09E-8 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 Gene3D G3DSA:3.30.70.1450 148 218 4.7E-9 T 23-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 PANTHER PTHR16254 9 161 2.0E-41 T 23-04-2016 SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 SUPERFAMILY SSF51735 6 136 4.84E-33 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 Gene3D G3DSA:3.40.50.720 3 139 1.1E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01475 e431129662ea4afefcfa26329019d92c 224 Pfam PF02254 TrkA-N domain 9 122 1.1E-27 T 23-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 SPYM18_RS05790 4eceb9fdeee59f2baf9f5a1c83fc4e85 103 PANTHER PTHR34581 2 103 3.3E-40 T 23-04-2016 SPYM18_RS05790 4eceb9fdeee59f2baf9f5a1c83fc4e85 103 Gene3D G3DSA:3.40.50.270 1 103 3.6E-38 T 23-04-2016 SPYM18_RS05790 4eceb9fdeee59f2baf9f5a1c83fc4e85 103 SUPERFAMILY SSF52794 1 102 8.63E-35 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS05790 4eceb9fdeee59f2baf9f5a1c83fc4e85 103 PANTHER PTHR34581:SF2 2 103 3.3E-40 T 23-04-2016 SPYM18_RS05790 4eceb9fdeee59f2baf9f5a1c83fc4e85 103 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 4 95 2.1E-22 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 Pfam PF02733 Dak1 domain 18 326 4.6E-89 T 23-04-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 PANTHER PTHR28629:SF2 1 329 7.2E-110 T 23-04-2016 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 Gene3D G3DSA:3.40.50.10440 12 180 5.6E-58 T 23-04-2016 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 TIGRFAM TIGR02362 dhaK1b: probable dihydroxyacetone kinase DhaK1b subunit 3 329 1.2E-176 T 23-04-2016 IPR012735 Dihydroxyacetone kinase DhaK, subunit 1b SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 Gene3D G3DSA:3.30.1180.20 184 329 3.2E-43 T 23-04-2016 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 SUPERFAMILY SSF82549 11 329 9.16E-102 T 23-04-2016 SPYM18_RS02520 6d9c84b66ca9b799a5a4e5e74f957251 329 PANTHER PTHR28629 1 329 7.2E-110 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 SUPERFAMILY SSF54001 184 298 2.26E-5 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 15 141 8.2E-19 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 Pfam PF08460 Bacterial SH3 domain 322 384 1.6E-7 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PRINTS PR01002 Flagellar protein FlgJ signature 80 101 3.0E-9 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PRINTS PR01002 Flagellar protein FlgJ signature 35 56 3.0E-9 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PRINTS PR01002 Flagellar protein FlgJ signature 122 140 3.0E-9 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PRINTS PR01002 Flagellar protein FlgJ signature 102 121 3.0E-9 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 SMART SM00047 2 145 2.7E-26 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PANTHER PTHR33308:SF3 16 146 3.2E-24 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 PANTHER PTHR33308 16 146 3.2E-24 T 23-04-2016 SPYM18_RS03345 2c47dd35b947f74eb43e596e6e3a9738 401 Pfam PF05257 CHAP domain 183 267 3.8E-7 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 118 283 7.6E-61 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 PANTHER PTHR32179 1 283 3.3E-126 T 23-04-2016 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 17 283 4.9E-111 T 23-04-2016 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|UniPathway: UPA00253 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 26 116 6.7E-26 T 23-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 SUPERFAMILY SSF54675 7 117 1.73E-28 T 23-04-2016 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 SUPERFAMILY SSF51690 118 283 1.77E-56 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 Gene3D G3DSA:3.20.20.70 139 274 5.9E-55 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 PIRSF PIRSF006250 9 286 1.0E-95 T 23-04-2016 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD SPYM18_RS05835 0470720320e03e0397f97603fb65c857 290 Gene3D G3DSA:3.90.1170.20 4 138 3.8E-46 T 23-04-2016 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 89 23.356 T 23-04-2016 IPR023036 Ribosomal protein S14, bacterial/plastid SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 Pfam PF00253 Ribosomal protein S14p/S29e 36 88 3.1E-25 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 Gene3D G3DSA:4.10.830.10 35 89 2.8E-28 T 23-04-2016 SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 PANTHER PTHR19836:SF20 1 89 3.4E-55 T 23-04-2016 SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 PANTHER PTHR19836 1 89 3.4E-55 T 23-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08345 487e03303902a63cb0319cdf8a9d55dd 89 SUPERFAMILY SSF57716 2 89 9.27E-27 T 23-04-2016 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Gene3D G3DSA:2.40.50.140 194 273 1.3E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SUPERFAMILY SSF50249 262 351 6.04E-27 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Gene3D G3DSA:2.40.50.140 274 349 1.1E-31 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Gene3D G3DSA:2.40.50.140 9 91 6.3E-13 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Gene3D G3DSA:2.40.50.140 105 174 4.7E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Pfam PF00575 S1 RNA binding domain 106 173 2.8E-12 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Pfam PF00575 S1 RNA binding domain 14 74 9.9E-9 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Pfam PF00575 S1 RNA binding domain 192 262 3.7E-21 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 Pfam PF00575 S1 RNA binding domain 276 348 6.4E-25 T 23-04-2016 IPR003029 S1 domain GO:0003676 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SUPERFAMILY SSF50249 4 103 7.09E-13 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 110 126 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 331 349 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 17 35 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 157 177 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 214 235 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 292 311 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PRINTS PR00681 Ribosomal protein S1 signature 128 145 1.7E-37 T 23-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 PANTHER PTHR10724 118 367 1.9E-89 T 23-04-2016 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SUPERFAMILY SSF50249 105 186 7.24E-15 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SMART SM00316 105 173 9.9E-9 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SMART SM00316 15 91 8.3E-7 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SMART SM00316 192 262 2.2E-25 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SMART SM00316 277 348 1.6E-27 T 23-04-2016 IPR022967 RNA-binding domain, S1 SPYM18_RS04200 51ec4eb2fc3bf908deee9d88d6e3b7a1 401 SUPERFAMILY SSF50249 193 279 2.24E-24 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS03140 29b0080a440414cd186adec8c38003b5 265 PIRSF PIRSF031475 3 265 2.5E-116 T 23-04-2016 IPR016974 Uncharacterised phage-associated protein SPYM18_RS03140 29b0080a440414cd186adec8c38003b5 265 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 22 255 4.8E-85 T 23-04-2016 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 297 410 7.9E-28 T 23-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 273 1.9E-63 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 Gene3D G3DSA:1.10.3420.10 289 455 2.7E-55 T 23-04-2016 IPR023292 NTP pyrophosphohydrolase-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 273 4.7E-53 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 PANTHER PTHR10000:SF25 1 279 8.1E-88 T 23-04-2016 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 ProSitePatterns PS01229 Hypothetical cof family signature 2. 227 249 - T 23-04-2016 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 Gene3D G3DSA:3.40.50.1000 3 72 8.7E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 Gene3D G3DSA:3.40.50.1000 182 279 8.7E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 PANTHER PTHR10000 1 279 8.1E-88 T 23-04-2016 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 SUPERFAMILY SSF56784 3 277 6.21E-62 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 PIRSF PIRSF037492 1 462 2.0E-267 T 23-04-2016 IPR017223 Predicted hydrolase of the HAD superfamily, SPs0319-type SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 246 1.4E-23 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS07995 f5b76d88cc0629a6cb508c02c60a637e 462 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 Pfam PF13177 DNA polymerase III, delta subunit 20 177 4.1E-44 T 23-04-2016 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 SUPERFAMILY SSF52540 33 222 2.23E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 350 1.7E-135 T 23-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 Gene3D G3DSA:3.40.50.300 14 165 1.3E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 Gene3D G3DSA:1.10.8.60 166 242 1.8E-30 T 23-04-2016 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 PANTHER PTHR11669 1 505 6.8E-175 T 23-04-2016 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 Gene3D G3DSA:1.20.272.10 254 351 1.3E-5 T 23-04-2016 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 PANTHER PTHR11669:SF0 1 505 6.8E-175 T 23-04-2016 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 254 359 2.7E-6 T 23-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 SMART SM00382 36 176 1.6E-6 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 123 141 1.66E-5 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 40 58 1.66E-5 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS05950 1010820439aa359e2d757ce8eeb31efb 556 SUPERFAMILY SSF48019 254 354 1.7E-10 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 SPYM18_RS04465 06f5db1e680845da5081b751cd0c8c4b 141 PANTHER PTHR33799 3 123 2.9E-19 T 23-04-2016 SPYM18_RS04465 06f5db1e680845da5081b751cd0c8c4b 141 Gene3D G3DSA:3.40.50.510 4 129 8.1E-18 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS04465 06f5db1e680845da5081b751cd0c8c4b 141 SUPERFAMILY SSF53062 1 125 1.57E-21 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS04465 06f5db1e680845da5081b751cd0c8c4b 141 Pfam PF03610 PTS system fructose IIA component 5 105 2.1E-8 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS04465 06f5db1e680845da5081b751cd0c8c4b 141 PANTHER PTHR33799:SF4 3 123 2.9E-19 T 23-04-2016 SPYM18_RS00705 3b0133fc21131f7a348a503e11f75466 333 Gene3D G3DSA:3.30.420.10 179 314 4.2E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS00705 3b0133fc21131f7a348a503e11f75466 333 SUPERFAMILY SSF53098 176 314 6.26E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS00705 3b0133fc21131f7a348a503e11f75466 333 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS00705 3b0133fc21131f7a348a503e11f75466 333 PANTHER PTHR10948 4 328 8.6E-83 T 23-04-2016 SPYM18_RS00705 3b0133fc21131f7a348a503e11f75466 333 Gene3D G3DSA:1.10.10.60 7 46 6.0E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS03435 9c6aaa2a7d079299fa61ec92e71fa314 152 Gene3D G3DSA:3.30.1330.30 1 130 3.4E-36 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS03435 9c6aaa2a7d079299fa61ec92e71fa314 152 PIRSF PIRSF034303 1 151 1.1E-48 T 23-04-2016 IPR012543 Protein of unknown function DUF1694 SPYM18_RS03435 9c6aaa2a7d079299fa61ec92e71fa314 152 Pfam PF07997 Protein of unknown function (DUF1694) 1 119 4.5E-32 T 23-04-2016 IPR012543 Protein of unknown function DUF1694 SPYM18_RS03435 9c6aaa2a7d079299fa61ec92e71fa314 152 SUPERFAMILY SSF160515 1 128 1.57E-34 T 23-04-2016 SPYM18_RS07345 363feaeed2497935749d4cac523d05da 185 SUPERFAMILY SSF46689 23 85 1.75E-10 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS07345 363feaeed2497935749d4cac523d05da 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 74 2.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPYM18_RS07345 363feaeed2497935749d4cac523d05da 185 Gene3D G3DSA:1.10.357.10 26 138 4.7E-12 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 Pfam PF07690 Major Facilitator Superfamily 15 351 4.3E-36 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 SUPERFAMILY SSF103473 6 390 8.24E-54 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 PANTHER PTHR23501 1 388 7.0E-126 T 23-04-2016 SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 Gene3D G3DSA:1.20.1250.20 7 188 3.7E-27 T 23-04-2016 SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 Gene3D G3DSA:1.20.1250.20 212 393 3.3E-17 T 23-04-2016 SPYM18_RS08275 f41ce2dad300caa7ed6388f4f1314e54 398 PANTHER PTHR23501:SF29 1 388 7.0E-126 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:1.10.486.10 613 764 3.9E-16 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070:SF14 870 1203 6.0E-256 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.40.50.300 367 467 4.4E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.40.50.300 124 187 4.4E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.40.50.300 29 92 4.4E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 26 1208 16.239 T 23-04-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070:SF14 332 747 6.0E-256 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070:SF14 764 826 6.0E-256 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 SUPERFAMILY SSF52980 1006 1202 3.81E-23 T 23-04-2016 IPR011335 Restriction endonuclease type II-like SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1045 1192 6.5E-9 T 23-04-2016 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 SUPERFAMILY SSF52540 28 200 2.4E-109 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 SUPERFAMILY SSF52540 871 896 2.4E-109 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 SUPERFAMILY SSF52540 357 815 2.4E-109 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070 332 747 6.0E-256 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070 764 826 6.0E-256 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 29 1203 4.8E-290 T 23-04-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Pfam PF00580 UvrD/REP helicase N-terminal domain 30 464 8.6E-79 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070 870 1203 6.0E-256 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.40.50.300 779 929 1.2E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.40.50.300 478 602 1.2E-53 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070 30 206 6.0E-256 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Pfam PF13361 UvrD-like helicase C-terminal domain 474 892 5.2E-31 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 Gene3D G3DSA:3.90.320.10 1044 1197 4.4E-12 T 23-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 SPYM18_RS03610 1435f573745faefbcbf0ca8b23e201ae 1210 PANTHER PTHR11070:SF14 30 206 6.0E-256 T 23-04-2016 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 PANTHER PTHR10210:SF41 1 322 2.0E-158 T 23-04-2016 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 Gene3D G3DSA:3.40.50.2020 6 166 2.7E-72 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 PANTHER PTHR10210 1 322 2.0E-158 T 23-04-2016 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 316 1.9E-103 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 2.7E-46 T 23-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 Gene3D G3DSA:3.40.50.2020 167 284 9.8E-37 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 23-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 SUPERFAMILY SSF53271 112 308 8.75E-44 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 44.87 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 SMART SM01400 10 126 6.6E-75 T 23-04-2016 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 316 7.1E-23 T 23-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 SPYM18_RS04675 109494c7cf59b89fcf10344b47d35739 326 SUPERFAMILY SSF53271 10 161 7.4E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 Gene3D G3DSA:3.10.105.10 340 584 1.8E-25 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 Gene3D G3DSA:3.40.190.10 212 339 1.4E-14 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290:SF10 405 584 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290:SF10 331 386 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290:SF10 1 313 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 84 106 - T 23-04-2016 IPR023765 Solute-binding protein family 5, conserved site SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290 405 584 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290 331 386 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 PANTHER PTHR30290 1 313 1.1E-112 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 Gene3D G3DSA:3.90.76.10 45 211 7.4E-41 T 23-04-2016 SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 516 6.7E-47 T 23-04-2016 IPR000914 Solute-binding protein family 5 domain SPYM18_RS01340 1d3842865d0014cbbe9b7abc0762f63a 656 SUPERFAMILY SSF53850 32 585 2.71E-75 T 23-04-2016 SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 Pfam PF01205 Uncharacterized protein family UPF0029 18 123 2.4E-30 T 23-04-2016 IPR001498 Impact, N-terminal SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 PANTHER PTHR16301 1 196 7.0E-55 T 23-04-2016 IPR023582 Impact family SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 195 9.2E-57 T 23-04-2016 IPR015796 Impact family, bacterial/archaeal SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 SUPERFAMILY SSF54211 3 130 7.59E-43 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 Gene3D G3DSA:3.30.230.30 5 130 2.0E-46 T 23-04-2016 IPR001498 Impact, N-terminal SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 3.1E-10 T 23-04-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 SUPERFAMILY SSF54980 137 200 6.47E-6 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 Gene3D G3DSA:3.30.70.240 138 202 1.7E-5 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-04-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site SPYM18_RS07025 745713e65971837daa5557651a0aa472 210 PANTHER PTHR16301:SF0 1 196 7.0E-55 T 23-04-2016 SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 PANTHER PTHR11562 4 283 5.1E-53 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 SUPERFAMILY SSF161111 4 197 2.75E-34 T 23-04-2016 SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 Gene3D G3DSA:1.20.1510.10 4 195 1.2E-33 T 23-04-2016 IPR027469 Cation efflux protein transmembrane domain SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 Pfam PF01545 Cation efflux family 8 190 3.3E-28 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 PANTHER PTHR11562:SF17 4 283 5.1E-53 T 23-04-2016 SPYM18_RS03895 6581b48aa1f32096f7403ae36b6bb8f1 291 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 273 2.8E-42 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS02665 82bb813123454ce157428da9693e8cca 100 PANTHER PTHR38781 2 98 2.6E-12 T 23-04-2016 SPYM18_RS02665 82bb813123454ce157428da9693e8cca 100 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 94 5.1E-27 T 23-04-2016 IPR007337 RelB antitoxin/Antitoxin DinJ SPYM18_RS02665 82bb813123454ce157428da9693e8cca 100 PANTHER PTHR38781:SF1 2 98 2.6E-12 T 23-04-2016 SPYM18_RS02665 82bb813123454ce157428da9693e8cca 100 Pfam PF04221 RelB antitoxin 4 87 1.2E-31 T 23-04-2016 IPR007337 RelB antitoxin/Antitoxin DinJ SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Pfam PF07724 AAA domain (Cdc48 subfamily) 443 600 2.2E-41 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 SMART SM00382 113 260 5.0E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 SMART SM00382 444 593 4.4E-11 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PANTHER PTHR11638 76 698 0.0 T 23-04-2016 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 118 250 2.5E-14 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 SUPERFAMILY SSF52540 393 675 5.12E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 SUPERFAMILY SSF52540 76 369 3.45E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 478 496 - T 23-04-2016 IPR028299 ClpA/B, conserved site 2 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Gene3D G3DSA:1.10.8.60 618 695 2.8E-23 T 23-04-2016 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PANTHER PTHR11638:SF101 76 698 0.0 T 23-04-2016 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 523 541 8.6E-28 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 493 511 8.6E-28 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 556 570 8.6E-28 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 448 466 8.6E-28 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 SMART SM01086 607 694 2.0E-24 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 607 678 1.6E-20 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Gene3D G3DSA:3.40.50.300 400 617 6.3E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Gene3D G3DSA:3.40.50.300 77 259 5.1E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04085 2d9ae228983f6e4e6a89f8ad0f68aebc 699 Gene3D G3DSA:1.10.8.60 261 342 1.4E-24 T 23-04-2016 SPYM18_RS03355 6d769cf6a3f83772fdc9a0ad1bc084fe 252 SMART SM00892 56 250 4.7E-7 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS03355 6d769cf6a3f83772fdc9a0ad1bc084fe 252 Pfam PF13930 DNA/RNA non-specific endonuclease 62 201 6.8E-22 T 23-04-2016 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 Pfam PF01381 Helix-turn-helix 9 61 1.1E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 PANTHER PTHR10245 1 124 7.3E-23 T 23-04-2016 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 Gene3D G3DSA:1.10.260.40 1 65 5.6E-25 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 SMART SM00530 6 61 1.6E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 SUPERFAMILY SSF47413 1 65 1.45E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08190 cc813773e5c1148fad8c569de8650569 195 PANTHER PTHR10245:SF47 1 124 7.3E-23 T 23-04-2016 SPYM18_RS03315 aa3ac9e595c318c8120eb65665ef37ba 628 SUPERFAMILY SSF58113 165 326 2.22E-6 T 23-04-2016 SPYM18_RS03315 aa3ac9e595c318c8120eb65665ef37ba 628 Pfam PF07902 gp58-like protein 1 600 3.0E-286 T 23-04-2016 IPR012892 Gp58-like SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 SUPERFAMILY SSF52540 185 256 1.32E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 SUPERFAMILY SSF52540 283 437 1.32E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 Pfam PF00772 DnaB-like helicase N terminal domain 12 112 8.1E-34 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 Pfam PF03796 DnaB-like helicase C terminal domain 187 443 4.2E-114 T 23-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 13 445 9.9E-173 T 23-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 Gene3D G3DSA:1.10.860.10 12 113 1.3E-34 T 23-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 PANTHER PTHR30153 1 445 7.2E-198 T 23-04-2016 SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 Gene3D G3DSA:3.40.50.300 173 445 5.7E-104 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01595 7da0bf081be91c08f90e369895c8bf29 451 SUPERFAMILY SSF48024 10 121 1.02E-34 T 23-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 Gene3D G3DSA:2.40.50.100 61 130 4.9E-28 T 23-04-2016 SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 Pfam PF00364 Biotin-requiring enzyme 65 130 3.4E-20 T 23-04-2016 IPR000089 Biotin/lipoyl attachment SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 87 104 - T 23-04-2016 IPR001882 Biotin-binding site SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 SUPERFAMILY SSF51230 56 130 1.16E-23 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 PANTHER PTHR18866 6 14 7.0E-19 T 23-04-2016 SPYM18_RS04910 7a716c825fe66b997e5f083f1e3ee421 131 PANTHER PTHR18866 53 130 7.0E-19 T 23-04-2016 SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 Gene3D G3DSA:3.50.80.10 1 144 9.9E-59 T 23-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 PANTHER PTHR10472 2 145 6.0E-77 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 1.6E-58 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 34.952 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 SUPERFAMILY SSF69500 1 144 1.18E-57 T 23-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain SPYM18_RS08800 9b7c730660d5aa84b2fca2e4b445adef 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 9.3E-55 T 23-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 SPYM18_RS06825 f2fdf712d7fcc8da8b39544c5e5d2186 84 SUPERFAMILY SSF140121 1 77 2.09E-39 T 23-04-2016 SPYM18_RS06825 f2fdf712d7fcc8da8b39544c5e5d2186 84 Gene3D G3DSA:1.20.58.90 1 84 1.5E-47 T 23-04-2016 SPYM18_RS06825 f2fdf712d7fcc8da8b39544c5e5d2186 84 Pfam PF08930 Domain of unknown function (DUF1912) 1 84 4.9E-48 T 23-04-2016 IPR015026 Protein of unknown function DUF1912 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 Gene3D G3DSA:3.50.50.60 221 272 1.4E-10 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 Gene3D G3DSA:3.50.50.60 15 76 1.4E-10 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 PANTHER PTHR37417 1 587 0.0 T 23-04-2016 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 SUPERFAMILY SSF51905 26 291 6.09E-21 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 Pfam PF06100 MCRA family 22 521 4.2E-214 T 23-04-2016 IPR010354 Oleate hydratase GO:0006631|GO:0050151|GO:0071949 UniPathway: UPA00199 SPYM18_RS02240 bc3cdb41a29777a3c67c7ef9e16b5a69 590 PANTHER PTHR37417:SF1 1 587 0.0 T 23-04-2016 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 Pfam PF02378 Phosphotransferase system, EIIC 28 348 1.5E-73 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 Gene3D G3DSA:3.40.50.270 461 560 1.3E-14 T 23-04-2016 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 TIGRFAM TIGR00853 pts-lac: PTS system, lactose/cellobiose family IIB component 422 554 7.9E-48 T 23-04-2016 IPR013012 Phosphotransferase system, EIIB component, type 3 GO:0008982|GO:0009401 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 SUPERFAMILY SSF52794 463 560 3.92E-12 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 PANTHER PTHR33989 1 441 1.7E-252 T 23-04-2016 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 464 528 1.6E-7 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 13 421 2.4E-83 T 23-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 PANTHER PTHR33989:SF6 1 441 1.7E-252 T 23-04-2016 SPYM18_RS08570 558cb2db09e5f524c5c861fbf2d04d7f 561 TIGRFAM TIGR00394 lac_pts_IIC: PTS system, lactose-specific IIC component 11 422 1.3E-233 T 23-04-2016 IPR004801 Phosphotransferase system, lactose-specific IIC component GO:0008982|GO:0016021|GO:0022869 SPYM18_RS09610 ea2c19ffc7bb54716152579077bf2790 858 Pfam PF09586 Bacterial membrane protein YfhO 14 837 3.8E-240 T 23-04-2016 IPR018580 Uncharacterised protein family YfhO SPYM18_RS09610 ea2c19ffc7bb54716152579077bf2790 858 PANTHER PTHR38454 1 855 1.1E-87 T 23-04-2016 SPYM18_RS09610 ea2c19ffc7bb54716152579077bf2790 858 PANTHER PTHR38454:SF1 1 855 1.1E-87 T 23-04-2016 SPYM18_RS02475 81606d76fd0d51eba8c805a557515a56 336 SUPERFAMILY SSF53098 176 314 6.45E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02475 81606d76fd0d51eba8c805a557515a56 336 Gene3D G3DSA:3.30.420.10 179 314 4.3E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02475 81606d76fd0d51eba8c805a557515a56 336 PANTHER PTHR10948 4 328 7.7E-84 T 23-04-2016 SPYM18_RS02475 81606d76fd0d51eba8c805a557515a56 336 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS02475 81606d76fd0d51eba8c805a557515a56 336 Gene3D G3DSA:1.10.10.60 7 46 6.0E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Gene3D G3DSA:3.90.190.20 305 453 1.4E-36 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Gene3D G3DSA:3.40.1190.10 81 302 7.7E-60 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 SUPERFAMILY SSF53623 101 302 2.22E-46 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Pfam PF08245 Mur ligase middle domain 105 284 1.5E-43 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Pfam PF01225 Mur ligase family, catalytic domain 26 72 2.3E-6 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 PANTHER PTHR23135:SF3 14 452 4.1E-140 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 388 2.0E-9 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Gene3D G3DSA:3.40.1390.10 1 75 1.6E-19 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 452 1.7E-107 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 PANTHER PTHR23135 14 452 4.1E-140 T 23-04-2016 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 SUPERFAMILY SSF53244 306 452 1.81E-31 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 453 31.907 T 23-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06170 0bf373309a19162058fa8d599d3f8ff7 463 SUPERFAMILY SSF63418 2 97 1.44E-20 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS05115 62e8b38075dd6fb956c095bc4c69fc03 208 Pfam PF05175 Methyltransferase small domain 39 203 8.3E-49 T 23-04-2016 IPR007848 Methyltransferase small domain GO:0008168 SPYM18_RS05115 62e8b38075dd6fb956c095bc4c69fc03 208 PANTHER PTHR18895 11 205 2.6E-86 T 23-04-2016 SPYM18_RS05115 62e8b38075dd6fb956c095bc4c69fc03 208 SUPERFAMILY SSF53335 18 205 6.39E-36 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05115 62e8b38075dd6fb956c095bc4c69fc03 208 Gene3D G3DSA:3.40.50.150 38 202 9.0E-31 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS05115 62e8b38075dd6fb956c095bc4c69fc03 208 PANTHER PTHR18895:SF72 11 205 2.6E-86 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 16 331 1.1E-75 T 23-04-2016 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 UniPathway: UPA00537|UniPathway: UPA00537 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 Gene3D G3DSA:3.30.390.50 253 338 1.7E-29 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 Pfam PF03099 Biotin/lipoate A/B protein ligase family 58 158 1.3E-6 T 23-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 PANTHER PTHR12561 13 339 1.8E-96 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 Gene3D G3DSA:3.90.1550.10 13 251 6.0E-66 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 SUPERFAMILY SSF82649 253 338 2.25E-24 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 254 337 1.3E-26 T 23-04-2016 IPR019491 Lipoate protein ligase, C-terminal UniPathway: UPA00537|UniPathway: UPA00537 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 SUPERFAMILY SSF55681 13 251 1.07E-64 T 23-04-2016 SPYM18_RS05035 6ec2adba3fc18cdbb1fb3d1db27fc469 339 PANTHER PTHR12561:SF3 13 339 1.8E-96 T 23-04-2016 SPYM18_RS08615 8d9cc536e48b59d842be354f56f5fcf9 156 Gene3D G3DSA:1.10.150.130 11 108 2.0E-12 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS08615 8d9cc536e48b59d842be354f56f5fcf9 156 SUPERFAMILY SSF56349 11 148 8.83E-22 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS08615 8d9cc536e48b59d842be354f56f5fcf9 156 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 11 67 3.1E-13 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 Pfam PF14794 Domain of unknown function (DUF4479) 23 89 2.9E-27 T 23-04-2016 IPR027855 Domain of unknown function DUF4479 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 Gene3D G3DSA:3.30.1940.10 20 89 1.3E-27 T 23-04-2016 IPR027855 Domain of unknown function DUF4479 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 Pfam PF01588 Putative tRNA binding domain 96 198 7.0E-20 T 23-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 SUPERFAMILY SSF50249 96 200 1.66E-29 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 PANTHER PTHR10947:SF0 86 198 6.2E-23 T 23-04-2016 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 PANTHER PTHR10947 86 198 6.2E-23 T 23-04-2016 SPYM18_RS00720 3d961ca897e392b4ec2a9bb1e972f87f 208 Gene3D G3DSA:2.40.50.140 96 205 6.1E-38 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 PIRSF PIRSF000379 11 763 2.1E-294 T 23-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 Gene3D G3DSA:3.20.70.20 9 762 2.4E-232 T 23-04-2016 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 Pfam PF02901 Pyruvate formate lyase-like 30 613 2.3E-151 T 23-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 SUPERFAMILY SSF51998 9 762 1.4E-202 T 23-04-2016 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 ProSitePatterns PS00850 Glycine radical domain signature. 733 741 - T 23-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 PANTHER PTHR30191 1 763 0.0 T 23-04-2016 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 14 763 0.0 T 23-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 Pfam PF01228 Glycine radical 642 742 1.4E-23 T 23-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 SPYM18_RS08245 3323aeea02683f48888d3a63c60dab7b 775 PANTHER PTHR30191:SF0 1 763 0.0 T 23-04-2016 SPYM18_RS02035 8c5b2ea356881345fd521182c3b0ba93 107 Pfam PF06156 Protein of unknown function (DUF972) 2 101 1.7E-31 T 23-04-2016 IPR010377 Initiation control protein YabA GO:0006260 SPYM18_RS02035 8c5b2ea356881345fd521182c3b0ba93 107 Hamap MF_01159 Initiation-control protein YabA. 1 106 22.779 T 23-04-2016 IPR010377 Initiation control protein YabA GO:0006260 SPYM18_RS02035 8c5b2ea356881345fd521182c3b0ba93 107 PIRSF PIRSF021439 1 107 2.4E-38 T 23-04-2016 IPR010377 Initiation control protein YabA GO:0006260 SPYM18_RS02035 8c5b2ea356881345fd521182c3b0ba93 107 PANTHER PTHR41240 2 107 5.4E-32 T 23-04-2016 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.5E-21 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.5E-21 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.5E-21 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 23-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 SUPERFAMILY SSF47729 3 91 1.77E-32 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 2.4E-34 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 Gene3D G3DSA:4.10.520.10 3 91 6.7E-38 T 23-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 SMART SM00411 2 91 4.5E-47 T 23-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 SPYM18_RS06490 ec6e41ee041d04d4c8af2aa38949ea5a 91 PANTHER PTHR33175 1 91 1.1E-44 T 23-04-2016 SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 SUPERFAMILY SSF51735 3 152 4.84E-45 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 Gene3D G3DSA:3.40.50.720 1 142 6.9E-44 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 4.0E-21 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 Gene3D G3DSA:3.30.360.10 143 318 1.7E-25 T 23-04-2016 SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 SUPERFAMILY SSF55347 129 289 4.25E-25 T 23-04-2016 SPYM18_RS06795 c03b8aec13216004af7eb4df582e4d78 319 PANTHER PTHR22604 1 317 1.1E-65 T 23-04-2016 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 242 5.3E-60 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 PANTHER PTHR21139 1 251 1.1E-122 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 Pfam PF00121 Triosephosphate isomerase 6 247 6.9E-92 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 Gene3D G3DSA:3.20.20.70 3 249 5.1E-104 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 23-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 SUPERFAMILY SSF51351 3 250 2.36E-91 T 23-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS02905 2b61880fdc7854419221ed50ca275c75 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 251 39.702 T 23-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 131 150 1.2E-8 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 83 95 1.2E-8 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 37 53 1.2E-8 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 PANTHER PTHR12383 9 165 2.7E-19 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 SUPERFAMILY SSF51306 36 167 8.63E-28 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 Gene3D G3DSA:2.10.109.10 131 166 3.5E-15 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 Gene3D G3DSA:2.10.109.10 35 93 3.5E-15 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 Pfam PF10502 Signal peptidase, peptidase S26 86 168 1.2E-6 T 23-04-2016 IPR019533 Peptidase S26 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 21 168 1.8E-34 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS00755 09e5d574f916399d09aaacb2555acf2d 173 PANTHER PTHR12383:SF14 9 165 2.7E-19 T 23-04-2016 SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 Gene3D G3DSA:1.10.150.240 19 82 2.3E-31 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 Gene3D G3DSA:3.40.50.1000 83 182 3.0E-25 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 Gene3D G3DSA:3.40.50.1000 4 18 3.0E-25 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 SUPERFAMILY SSF56784 4 183 2.91E-33 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 9 172 6.0E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03420 ea9bafa6955c9259401b1ad62ea3b087 189 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 178 1.1E-15 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 SUPERFAMILY SSF110710 3 185 1.78E-76 T 23-04-2016 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 24 185 1.0E-88 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 PIRSF PIRSF007510 1 181 7.0E-86 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 Gene3D G3DSA:3.40.50.10360 3 185 5.9E-80 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 Pfam PF04260 Protein of unknown function (DUF436) 8 178 2.9E-69 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 7 178 3.7E-74 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS08455 033fbd38831ad344666fe352bca4791f 186 Hamap MF_00800 UPF0340 protein . 1 186 90.554 T 23-04-2016 IPR006340 Protein of unknown function DUF436 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 PRINTS PR00297 10kDa chaperonin signature 2 17 3.3E-10 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 PRINTS PR00297 10kDa chaperonin signature 24 45 3.3E-10 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 PRINTS PR00297 10kDa chaperonin signature 81 94 3.3E-10 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 SMART SM00883 1 94 3.9E-28 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 1.2E-18 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 SUPERFAMILY SSF50129 1 94 2.71E-20 T 23-04-2016 IPR011032 GroES-like SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 PANTHER PTHR10772 2 94 4.9E-14 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 23-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 Gene3D G3DSA:2.30.33.40 2 94 4.8E-21 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS09120 40114bedfc596527c8a4c60ac5a4d74d 96 Hamap MF_00580 10 kDa chaperonin [groS]. 1 95 17.526 T 23-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 PANTHER PTHR10578 12 393 5.6E-152 T 23-04-2016 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 PANTHER PTHR10578:SF65 12 393 5.6E-152 T 23-04-2016 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 Gene3D G3DSA:3.20.20.70 29 381 1.4E-124 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 Pfam PF01070 FMN-dependent dehydrogenase 39 371 2.6E-105 T 23-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 TIGRFAM TIGR02708 L_lactate_ox: L-lactate oxidase 17 382 2.9E-226 T 23-04-2016 IPR014080 L-lactate oxidase KEGG: 00620+1.13.12.4 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 PIRSF PIRSF000138 7 379 1.6E-129 T 23-04-2016 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 SPYM18_RS02065 34cd2800597fc3142a12785c8133e6d2 393 SUPERFAMILY SSF51395 29 370 2.62E-81 T 23-04-2016 SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 PANTHER PTHR11203 1 553 3.1E-264 T 23-04-2016 SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 Pfam PF00753 Metallo-beta-lactamase superfamily 16 163 2.6E-13 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 353 408 9.9E-11 T 23-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 550 9.6E-151 T 23-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 SMART SM00849 16 212 6.6E-22 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 39.722 T 23-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 Gene3D G3DSA:3.60.15.10 2 253 3.5E-67 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 SUPERFAMILY SSF56281 4 419 3.3E-71 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS04340 a77ae720fc82d2ce7fbe75a8b8cfa88b 553 PANTHER PTHR11203:SF38 1 553 3.1E-264 T 23-04-2016 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 SUPERFAMILY SSF56601 8 297 2.66E-68 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 8.1E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 117 134 8.1E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 61 72 8.1E-14 T 23-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 Gene3D G3DSA:2.60.410.10 302 399 9.4E-19 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 PANTHER PTHR21581:SF11 4 365 2.7E-97 T 23-04-2016 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 PANTHER PTHR21581 4 365 2.7E-97 T 23-04-2016 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 SMART SM00936 299 399 1.0E-9 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 399 3.0E-14 T 23-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 275 1.4E-73 T 23-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 SUPERFAMILY SSF69189 291 371 4.51E-11 T 23-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 SPYM18_RS04540 955600b5cc9db95977aee2a2ec18dd56 415 Gene3D G3DSA:3.40.710.10 26 298 3.9E-84 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS01915 30780279058f247c9063e979966eb572 86 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 2 69 23.466 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor SPYM18_RS01915 30780279058f247c9063e979966eb572 86 SMART SM01234 2 68 2.8E-40 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor SPYM18_RS01915 30780279058f247c9063e979966eb572 86 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 17 68 8.0E-25 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor SPYM18_RS01915 30780279058f247c9063e979966eb572 86 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 6 71 9.3E-27 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor SPYM18_RS01915 30780279058f247c9063e979966eb572 86 Pfam PF01809 Haemolytic domain 3 68 3.8E-27 T 23-04-2016 IPR002696 Putative membrane protein insertion efficiency factor SPYM18_RS01915 30780279058f247c9063e979966eb572 86 PANTHER PTHR33383 1 73 7.9E-36 T 23-04-2016 SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 23 108 1.1E-13 T 23-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 SUPERFAMILY SSF51735 121 284 4.6E-24 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 SUPERFAMILY SSF53223 14 120 1.15E-18 T 23-04-2016 SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 PANTHER PTHR21089 1 281 1.1E-42 T 23-04-2016 SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 Gene3D G3DSA:3.40.50.720 125 281 7.8E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 Gene3D G3DSA:3.40.192.10 17 124 4.0E-24 T 23-04-2016 SPYM18_RS02600 333b9c1bc09684dce350ea0f4fee586a 308 PANTHER PTHR21089:SF1 1 281 1.1E-42 T 23-04-2016 SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 PANTHER PTHR24220 9 244 7.1E-98 T 23-04-2016 SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 Pfam PF00005 ABC transporter 23 171 2.2E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 SUPERFAMILY SSF52540 6 234 4.49E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 SMART SM00382 32 229 6.4E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 Gene3D G3DSA:3.40.50.300 3 235 4.4E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08045 4f245fa6a04311df70e3af40bfda025d 278 PANTHER PTHR24220:SF438 9 244 7.1E-98 T 23-04-2016 SPYM18_RS06145 04ddcfe171b06669229919e6a8dc94d7 92 PANTHER PTHR34477:SF1 1 90 5.5E-29 T 23-04-2016 SPYM18_RS06145 04ddcfe171b06669229919e6a8dc94d7 92 PANTHER PTHR34477 1 90 5.5E-29 T 23-04-2016 SPYM18_RS06145 04ddcfe171b06669229919e6a8dc94d7 92 Pfam PF01541 GIY-YIG catalytic domain 6 75 6.0E-17 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily SPYM18_RS06145 04ddcfe171b06669229919e6a8dc94d7 92 SUPERFAMILY SSF82771 5 72 1.22E-14 T 23-04-2016 IPR000305 GIY-YIG nuclease superfamily SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 PANTHER PTHR36174 1 408 5.1E-104 T 23-04-2016 SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 Gene3D G3DSA:3.40.630.30 171 239 1.0E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 Gene3D G3DSA:3.40.630.30 297 371 1.0E-37 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 SUPERFAMILY SSF55729 297 382 2.58E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 SUPERFAMILY SSF55729 167 240 2.58E-26 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 PANTHER PTHR36174:SF1 1 408 5.1E-104 T 23-04-2016 SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 SUPERFAMILY SSF55729 5 164 1.85E-46 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 Pfam PF02388 FemAB family 8 383 2.1E-112 T 23-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 SPYM18_RS02915 046f08342320df82bb60e463c2c63e9d 408 Gene3D G3DSA:3.40.630.30 1 170 3.1E-60 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 23-04-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 SUPERFAMILY SSF54747 3 72 1.57E-29 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 Gene3D G3DSA:3.30.1550.10 2 71 7.8E-38 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 1.4E-63 T 23-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 2.0E-26 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 SMART SM00649 9 140 6.1E-86 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 SUPERFAMILY SSF46906 67 139 8.63E-28 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.413 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 6.0E-16 T 23-04-2016 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 PANTHER PTHR11661 1 139 8.5E-72 T 23-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 Gene3D G3DSA:1.10.10.250 72 139 9.7E-34 T 23-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 SPYM18_RS02200 50a3e73021bb06f01d25c6318b699b37 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.2E-30 T 23-04-2016 IPR020784 Ribosomal protein L11, N-terminal SPYM18_RS09085 acf2fc266d971d3b35559c891a4f8592 126 Gene3D G3DSA:3.30.1330.40 3 123 8.2E-38 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPYM18_RS09085 acf2fc266d971d3b35559c891a4f8592 126 SUPERFAMILY SSF55298 9 120 1.18E-25 T 23-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 SUPERFAMILY SSF54373 253 349 3.66E-11 T 23-04-2016 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 Pfam PF01266 FAD dependent oxidoreductase 21 352 5.0E-50 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 SUPERFAMILY SSF51905 7 124 4.63E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 SUPERFAMILY SSF51905 160 254 4.63E-31 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 Gene3D G3DSA:3.50.50.60 14 361 8.2E-46 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 465 587 3.3E-17 T 23-04-2016 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 343 349 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 425 437 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 7.29E-30 T 23-04-2016 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PANTHER PTHR11985 7 357 5.2E-177 T 23-04-2016 SPYM18_RS07285 452a9a19c9c29691de9071655cc697f6 612 PANTHER PTHR11985 408 612 5.2E-177 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 Pfam PF01134 Glucose inhibited division protein A 10 402 7.9E-164 T 23-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 Pfam PF13932 GidA associated domain 404 619 1.9E-69 T 23-04-2016 IPR026904 GidA associated domain 3 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 PANTHER PTHR11806 4 631 0.0 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 PANTHER PTHR11806:SF0 4 631 0.0 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.5E-5 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 140 149 3.5E-5 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 SUPERFAMILY SSF51905 7 68 5.7E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 SUPERFAMILY SSF51905 99 262 5.7E-43 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 Gene3D G3DSA:3.50.50.60 9 235 2.4E-34 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 23-04-2016 IPR020595 MnmG-related, conserved site SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 SMART SM01228 549 620 9.7E-41 T 23-04-2016 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 627 41.409 T 23-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 23-04-2016 IPR020595 MnmG-related, conserved site SPYM18_RS09495 25633a08a240ec06e43eac0292a41502 632 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 623 3.0E-274 T 23-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 SPYM18_RS09400 0c900b94dc2c9945e9b7f0bfe1e8d973 204 Pfam PF03596 Cadmium resistance transporter 12 202 4.8E-90 T 23-04-2016 IPR004676 Cadmium resistance transporter SPYM18_RS09400 0c900b94dc2c9945e9b7f0bfe1e8d973 204 TIGRFAM TIGR00779 cad: cadmium resistance transporter family protein 13 201 1.4E-63 T 23-04-2016 IPR004676 Cadmium resistance transporter SPYM18_RS04325 8468f2154a4462be5a6a302f18fa15c7 332 PANTHER PTHR35271 8 332 9.6E-55 T 23-04-2016 SPYM18_RS04325 8468f2154a4462be5a6a302f18fa15c7 332 Pfam PF04392 ABC transporter substrate binding protein 40 330 2.6E-122 T 23-04-2016 IPR007487 ABC transporter, substrate-binding protein SPYM18_RS04325 8468f2154a4462be5a6a302f18fa15c7 332 Gene3D G3DSA:3.40.50.2300 165 298 5.1E-50 T 23-04-2016 SPYM18_RS04325 8468f2154a4462be5a6a302f18fa15c7 332 SUPERFAMILY SSF53822 48 299 1.63E-15 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS04325 8468f2154a4462be5a6a302f18fa15c7 332 Gene3D G3DSA:3.40.50.2300 38 164 2.5E-50 T 23-04-2016 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 PANTHER PTHR31801:SF0 6 232 4.5E-41 T 23-04-2016 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 Pfam PF01987 Mitochondrial biogenesis AIM24 8 217 5.2E-49 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 6 233 3.4E-35 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 Gene3D G3DSA:3.60.160.10 3 235 4.3E-80 T 23-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 PANTHER PTHR31801 6 232 4.5E-41 T 23-04-2016 SPYM18_RS01110 acc6436a704fb41f1b46384e42f1c58f 236 SUPERFAMILY SSF51219 6 231 1.62E-65 T 23-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 PANTHER PTHR11089 4 278 2.2E-69 T 23-04-2016 SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 Gene3D G3DSA:3.40.50.300 16 178 2.9E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 SUPERFAMILY SSF52540 10 191 3.66E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 274 5.7E-108 T 23-04-2016 IPR019991 GTP-binding protein, ribosome biogenesis SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 Pfam PF01926 50S ribosome-binding GTPase 124 190 4.6E-15 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 PIRSF PIRSF006230 1 279 5.7E-98 T 23-04-2016 IPR016478 GTPase, MTG1 SPYM18_RS04845 7faff132d04fcaca1d699f1852d6bdd4 282 Gene3D G3DSA:1.10.1580.10 181 268 1.5E-23 T 23-04-2016 IPR023179 GTP-binding protein, orthogonal bundle domain SPYM18_RS08070 89e5305106ce78888ed3edd9ab971b2a 515 SUPERFAMILY SSF54001 390 511 8.93E-17 T 23-04-2016 SPYM18_RS08070 89e5305106ce78888ed3edd9ab971b2a 515 Pfam PF05257 CHAP domain 401 486 1.6E-17 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 212 232 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 135 153 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 80 99 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 165 187 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 43 67 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PRINTS PR00783 Major intrinsic protein family signature 1 19 5.8E-42 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 ProSitePatterns PS00221 MIP family signature. 61 69 - T 23-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PANTHER PTHR19139:SF147 3 232 1.9E-82 T 23-04-2016 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 PANTHER PTHR19139 3 232 1.9E-82 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 Gene3D G3DSA:1.20.1080.10 3 232 1.3E-76 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 Pfam PF00230 Major intrinsic protein 3 229 5.4E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS07280 c77cb88a9c24e3296a8fe9dfcb0b6f92 233 SUPERFAMILY SSF81338 3 232 6.41E-65 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 Gene3D G3DSA:3.40.1160.10 2 237 1.4E-82 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 Hamap MF_01220_B Uridylate kinase [pyrH]. 3 237 43.02 T 23-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 PIRSF PIRSF005650 1 242 7.7E-91 T 23-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 PANTHER PTHR21499 1 238 5.4E-109 T 23-04-2016 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 PANTHER PTHR21499:SF23 1 238 5.4E-109 T 23-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 SUPERFAMILY SSF53633 3 238 3.14E-71 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 5 236 1.0E-95 T 23-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 SPYM18_RS02210 1bb9d31275dc3574ac87d3f207b5483a 242 Pfam PF00696 Amino acid kinase family 6 216 8.0E-26 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS05475 1e1c348269e749072a4af979e611af4d 80 Pfam PF12949 HeH/LEM domain 45 77 2.2E-9 T 23-04-2016 IPR025856 HeH/LEM domain SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PANTHER PTHR30409 1 316 2.0E-147 T 23-04-2016 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 75 93 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 110 129 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 159 178 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 182 200 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 43 62 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.9E-64 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 Pfam PF00696 Amino acid kinase family 5 296 1.4E-30 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 Gene3D G3DSA:3.40.1160.10 3 314 3.4E-109 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PIRSF PIRSF000723 2 315 5.8E-123 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 PANTHER PTHR30409:SF1 1 316 2.0E-147 T 23-04-2016 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 TIGRFAM TIGR00746 arcC: carbamate kinase 5 314 3.1E-132 T 23-04-2016 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 SPYM18_RS06715 157172274a0bc3b2a0ad8bdc6b787afb 316 SUPERFAMILY SSF53633 4 313 1.11E-86 T 23-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 PANTHER PTHR30255:SF2 2 728 6.9E-259 T 23-04-2016 SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 588 727 4.4E-31 T 23-04-2016 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 Pfam PF01368 DHH family 83 228 5.5E-14 T 23-04-2016 IPR001667 DDH domain SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 Pfam PF02272 DHHA1 domain 371 431 5.9E-10 T 23-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 29 556 6.2E-171 T 23-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 SUPERFAMILY SSF64182 58 435 1.14E-113 T 23-04-2016 SPYM18_RS04255 284c21314148b0387911f0dd5ff2e6c4 736 PANTHER PTHR30255 2 728 6.9E-259 T 23-04-2016 SPYM18_RS03805 f5c50766c81c75238ac2fc7dc8556da3 108 Gene3D G3DSA:3.30.70.1490 9 108 2.9E-13 T 23-04-2016 SPYM18_RS03805 f5c50766c81c75238ac2fc7dc8556da3 108 PANTHER PTHR39178 2 108 1.6E-25 T 23-04-2016 SPYM18_RS03805 f5c50766c81c75238ac2fc7dc8556da3 108 Pfam PF04327 Cysteine peptidase C108, N-terminal of ribosomal L27 1 103 2.1E-23 T 23-04-2016 IPR007422 Cysteine peptidase C108, N-terminal of ribosomal L27 SPYM18_RS03805 f5c50766c81c75238ac2fc7dc8556da3 108 SUPERFAMILY SSF118010 1 105 1.57E-29 T 23-04-2016 SPYM18_RS01715 bbaba21bcdf620d5203ee1ed28c04c5d 377 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 10 235 1.1E-15 T 23-04-2016 IPR006444 Phage major capsid protein, HK97 SPYM18_RS01715 bbaba21bcdf620d5203ee1ed28c04c5d 377 SUPERFAMILY SSF56563 89 374 2.75E-14 T 23-04-2016 SPYM18_RS01715 bbaba21bcdf620d5203ee1ed28c04c5d 377 Pfam PF05065 Phage capsid family 90 232 1.7E-11 T 23-04-2016 IPR024455 Phage capsid SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 Gene3D G3DSA:1.10.10.10 141 198 6.8E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.8E-8 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 SUPERFAMILY SSF46894 129 197 1.5E-14 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 SMART SM00448 1 116 1.5E-16 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 190 1.3E-12 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 SUPERFAMILY SSF52172 1 128 5.41E-21 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 SMART SM00421 135 192 1.9E-10 T 23-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 PANTHER PTHR26402 1 189 3.8E-31 T 23-04-2016 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 PANTHER PTHR26402:SF458 1 189 3.8E-31 T 23-04-2016 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 Gene3D G3DSA:3.40.50.2300 1 140 3.7E-26 T 23-04-2016 SPYM18_RS08535 41d59b05082301a13435b0cd758cef81 201 Pfam PF00072 Response regulator receiver domain 3 116 5.2E-19 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 SMART SM00530 7 63 2.3E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 Pfam PF00717 Peptidase S24-like 167 233 1.2E-12 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 Pfam PF01381 Helix-turn-helix 8 63 8.7E-14 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 Gene3D G3DSA:2.10.109.10 133 251 3.1E-26 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 SUPERFAMILY SSF51306 133 249 4.97E-25 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 PANTHER PTHR10245 91 251 7.8E-19 T 23-04-2016 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 PANTHER PTHR10245 2 70 7.8E-19 T 23-04-2016 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 PANTHER PTHR10245:SF32 91 251 7.8E-19 T 23-04-2016 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 PANTHER PTHR10245:SF32 2 70 7.8E-19 T 23-04-2016 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 SUPERFAMILY SSF47413 2 69 2.11E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS06475 0cef77d222fa3e1a710e345c70464234 251 Gene3D G3DSA:1.10.260.40 1 65 2.1E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02620 66bbab3fc980de0171ae4ce3be2e2823 399 PANTHER PTHR36697 1 392 1.7E-61 T 23-04-2016 SPYM18_RS02620 66bbab3fc980de0171ae4ce3be2e2823 399 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 16 376 0.0 T 23-04-2016 SPYM18_RS02620 66bbab3fc980de0171ae4ce3be2e2823 399 PANTHER PTHR36697:SF1 1 392 1.7E-61 T 23-04-2016 SPYM18_RS02620 66bbab3fc980de0171ae4ce3be2e2823 399 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 16 385 3.9E-76 T 23-04-2016 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|UniPathway: UPA00315 SPYM18_RS06500 f657c0fd427a04225df6bc1d14ccccee 280 Gene3D G3DSA:3.40.50.1110 48 276 2.1E-59 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS06500 f657c0fd427a04225df6bc1d14ccccee 280 PANTHER PTHR30383 48 280 6.0E-27 T 23-04-2016 SPYM18_RS06500 f657c0fd427a04225df6bc1d14ccccee 280 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 262 2.4E-28 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS06500 f657c0fd427a04225df6bc1d14ccccee 280 SUPERFAMILY SSF52266 48 274 4.51E-44 T 23-04-2016 IPR013830 SGNH hydrolase-type esterase domain SPYM18_RS05365 d92a6b080eedc38bf98e053d7f129fa5 237 Gene3D G3DSA:2.40.50.110 44 109 6.8E-4 T 23-04-2016 SPYM18_RS05365 d92a6b080eedc38bf98e053d7f129fa5 237 Gene3D G3DSA:3.10.20.120 110 232 1.7E-24 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS05365 d92a6b080eedc38bf98e053d7f129fa5 237 SUPERFAMILY SSF54334 125 233 2.36E-26 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS05365 d92a6b080eedc38bf98e053d7f129fa5 237 SUPERFAMILY SSF50203 29 108 2.0E-5 T 23-04-2016 IPR008992 Enterotoxin GO:0009405 SPYM18_RS05365 d92a6b080eedc38bf98e053d7f129fa5 237 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 132 230 9.4E-11 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS06060 471e4c9ae7bf85d394b58758262e11a9 351 SUPERFAMILY SSF109998 31 175 1.49E-17 T 23-04-2016 IPR027304 Trigger factor/SurA domain SPYM18_RS06060 471e4c9ae7bf85d394b58758262e11a9 351 Hamap MF_01145 Foldase protein PrsA [prsA]. 5 298 19.693 T 23-04-2016 IPR023059 Foldase protein PrsA GO:0003755 SPYM18_RS06060 471e4c9ae7bf85d394b58758262e11a9 351 Pfam PF13145 PPIC-type PPIASE domain 133 252 1.3E-15 T 23-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SPYM18_RS06060 471e4c9ae7bf85d394b58758262e11a9 351 SUPERFAMILY SSF54534 150 241 1.02E-7 T 23-04-2016 SPYM18_RS06060 471e4c9ae7bf85d394b58758262e11a9 351 Gene3D G3DSA:3.10.50.40 146 241 2.7E-7 T 23-04-2016 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 Gene3D G3DSA:3.60.20.10 12 255 1.5E-67 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 PIRSF PIRSF000485 8 474 2.0E-174 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 Pfam PF00156 Phosphoribosyl transferase domain 277 385 3.2E-8 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 1.0E-154 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 PANTHER PTHR11907 9 471 1.7E-234 T 23-04-2016 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 459 46.102 T 23-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 Pfam PF13537 Glutamine amidotransferase domain 94 210 2.0E-19 T 23-04-2016 IPR017932 Glutamine amidotransferase type 2 domain SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 PANTHER PTHR11907:SF0 9 471 1.7E-234 T 23-04-2016 SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 SUPERFAMILY SSF56235 12 238 1.8E-67 T 23-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 Gene3D G3DSA:3.40.50.2020 270 435 7.3E-45 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS00275 a99e40d2311164070538f2dd954eeebf 484 SUPERFAMILY SSF53271 248 465 1.31E-72 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Gene3D G3DSA:3.40.50.300 441 665 2.6E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 162 281 1.4E-13 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 253 265 - T 23-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Pfam PF02151 UvrB/uvrC motif 372 406 9.7E-8 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 SMART SM00382 157 297 1.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 SMART SM00382 486 657 6.5E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Gene3D G3DSA:4.10.860.10 376 409 6.6E-4 T 23-04-2016 IPR001943 UVR domain GO:0005515 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 SUPERFAMILY SSF52540 119 371 6.69E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Gene3D G3DSA:1.10.8.60 301 375 3.1E-30 T 23-04-2016 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PANTHER PTHR11638:SF117 108 760 0.0 T 23-04-2016 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Gene3D G3DSA:3.40.50.300 120 300 2.7E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 597 611 1.9E-37 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 490 508 1.9E-37 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 564 582 1.9E-37 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 535 553 1.9E-37 T 23-04-2016 IPR001270 ClpA/B family GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 SUPERFAMILY SSF52540 435 728 3.16E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 730 3.5E-22 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 SMART SM01086 656 744 2.8E-26 T 23-04-2016 IPR019489 Clp ATPase, C-terminal SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Gene3D G3DSA:1.10.8.60 666 745 8.3E-26 T 23-04-2016 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 520 538 - T 23-04-2016 IPR028299 ClpA/B, conserved site 2 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 Pfam PF07724 AAA domain (Cdc48 subfamily) 485 648 5.7E-49 T 23-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 SPYM18_RS06575 566f98eacb5fa46bc0c4255a1d6113f2 760 PANTHER PTHR11638 108 760 0.0 T 23-04-2016 SPYM18_RS01025 8c4466c8a617728e62de029ef45a4194 259 SMART SM00849 18 213 1.7E-13 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS01025 8c4466c8a617728e62de029ef45a4194 259 SUPERFAMILY SSF56281 1 237 1.05E-44 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS01025 8c4466c8a617728e62de029ef45a4194 259 Gene3D G3DSA:3.60.15.10 1 234 9.4E-44 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS01025 8c4466c8a617728e62de029ef45a4194 259 PANTHER PTHR12553 1 247 7.6E-36 T 23-04-2016 SPYM18_RS01025 8c4466c8a617728e62de029ef45a4194 259 Pfam PF12706 Beta-lactamase superfamily domain 36 214 6.1E-19 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 PANTHER PTHR30061 14 394 3.9E-39 T 23-04-2016 SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 PANTHER PTHR30061:SF21 14 394 3.9E-39 T 23-04-2016 SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 Gene3D G3DSA:3.40.190.10 36 160 5.6E-23 T 23-04-2016 SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 Gene3D G3DSA:3.40.190.10 161 339 2.0E-30 T 23-04-2016 SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 Pfam PF13416 Bacterial extracellular solute-binding protein 57 355 1.1E-49 T 23-04-2016 SPYM18_RS05705 414c184cd804300b4857ce9a3725bcf6 415 SUPERFAMILY SSF53850 40 391 2.99E-59 T 23-04-2016 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 ProSitePatterns PS00211 ABC transporters family signature. 470 484 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 SUPERFAMILY SSF52540 329 567 3.39E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 Pfam PF00664 ABC transporter transmembrane region 16 283 1.5E-35 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 PANTHER PTHR24221:SF190 1 572 4.0E-127 T 23-04-2016 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 PANTHER PTHR24221 1 572 4.0E-127 T 23-04-2016 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 SUPERFAMILY SSF90123 2 314 1.96E-59 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 Gene3D G3DSA:1.20.1560.10 1 314 3.5E-56 T 23-04-2016 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 Pfam PF00005 ABC transporter 350 497 1.5E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 Gene3D G3DSA:3.40.50.300 330 561 3.5E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04790 3df0749a431b561facc6f85204e318de 572 SMART SM00382 357 544 6.1E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 Gene3D G3DSA:3.40.50.2300 1 131 6.5E-13 T 23-04-2016 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 Pfam PF00072 Response regulator receiver domain 3 119 6.4E-10 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 SMART SM00448 1 122 3.8E-9 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 PANTHER PTHR26402:SF577 1 243 2.5E-38 T 23-04-2016 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 Pfam PF04397 LytTr DNA-binding domain 150 239 1.2E-20 T 23-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 Gene3D G3DSA:2.40.50.40 139 206 6.9E-14 T 23-04-2016 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 SMART SM00850 148 242 1.1E-17 T 23-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 SUPERFAMILY SSF52172 1 128 8.11E-10 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS02330 86a259c6c44ceaf577b84503802fe805 249 PANTHER PTHR26402 1 243 2.5E-38 T 23-04-2016 SPYM18_RS09280 001e8bc07325ed5f231da15d735d14be 101 PANTHER PTHR40066:SF1 1 100 1.6E-27 T 23-04-2016 SPYM18_RS09280 001e8bc07325ed5f231da15d735d14be 101 Hamap MF_01448 UPF0473 protein . 10 100 23.039 T 23-04-2016 IPR009711 Uncharacterised protein family UPF0473 SPYM18_RS09280 001e8bc07325ed5f231da15d735d14be 101 PANTHER PTHR40066 1 100 1.6E-27 T 23-04-2016 SPYM18_RS09280 001e8bc07325ed5f231da15d735d14be 101 Pfam PF06949 Protein of unknown function (DUF1292) 19 99 6.5E-16 T 23-04-2016 IPR009711 Uncharacterised protein family UPF0473 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 SUPERFAMILY SSF52540 4 190 2.25E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 PANTHER PTHR23117 1 201 6.5E-92 T 23-04-2016 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 36.29 T 23-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 PANTHER PTHR23117:SF13 1 201 6.5E-92 T 23-04-2016 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 Gene3D G3DSA:3.40.50.300 88 202 5.1E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 Gene3D G3DSA:3.40.50.300 3 27 5.1E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 SMART SM00072 4 187 1.0E-71 T 23-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 2.0E-71 T 23-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 23-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 Pfam PF00625 Guanylate kinase 7 185 2.5E-50 T 23-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit SPYM18_RS07090 92299d05c383dab93ccfa03229cdf5cf 211 Gene3D G3DSA:3.30.63.10 35 87 5.5E-28 T 23-04-2016 SPYM18_RS01980 e1aa91895091661d4e1803632a3342b4 343 SUPERFAMILY SSF81345 14 339 3.01E-73 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS01980 e1aa91895091661d4e1803632a3342b4 343 PANTHER PTHR30472:SF1 19 342 4.9E-100 T 23-04-2016 SPYM18_RS01980 e1aa91895091661d4e1803632a3342b4 343 Gene3D G3DSA:1.10.3470.10 20 341 1.5E-87 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS01980 e1aa91895091661d4e1803632a3342b4 343 PANTHER PTHR30472 19 342 4.9E-100 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS01980 e1aa91895091661d4e1803632a3342b4 343 Pfam PF01032 FecCD transport family 31 339 4.7E-82 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 SMART SM00940 1 145 3.3E-76 T 23-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 SUPERFAMILY SSF81761 1 147 1.23E-44 T 23-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Hamap MF_00698 Xaa-Pro dipeptidyl-peptidase [pepX]. 1 757 36.749 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 SUPERFAMILY SSF49785 551 759 1.26E-69 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 SMART SM00939 515 754 1.4E-53 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Gene3D G3DSA:3.40.50.1820 163 215 3.9E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Gene3D G3DSA:3.40.50.1820 264 382 3.9E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Gene3D G3DSA:3.40.50.1820 456 542 3.9E-51 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 530 751 1.9E-25 T 23-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 SUPERFAMILY SSF53474 149 547 3.21E-99 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 184 501 3.9E-84 T 23-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731:SF148 437 536 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731:SF148 265 400 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731:SF148 164 214 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Pfam PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal 1 145 3.9E-47 T 23-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731 437 536 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731 265 400 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PANTHER PTHR11731 164 214 1.0E-47 T 23-04-2016 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Gene3D G3DSA:2.60.120.260 677 757 6.8E-62 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 Gene3D G3DSA:2.60.120.260 543 638 6.8E-62 T 23-04-2016 IPR008979 Galactose-binding domain-like SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 188 197 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 507 523 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 170 180 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 154 166 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 202 218 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 722 737 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS08285 d61d1f3a84dcc95be5e9613d26412431 760 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 372 388 1.3E-38 T 23-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 SPYM18_RS04295 03cbb3c6dd5982c98e127efb6828b179 197 PANTHER PTHR21047 2 192 6.3E-39 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SPYM18_RS04295 03cbb3c6dd5982c98e127efb6828b179 197 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 15 192 3.0E-101 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SPYM18_RS04295 03cbb3c6dd5982c98e127efb6828b179 197 Gene3D G3DSA:2.60.120.10 16 192 8.4E-53 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS04295 03cbb3c6dd5982c98e127efb6828b179 197 SUPERFAMILY SSF51182 17 192 1.19E-49 T 23-04-2016 IPR011051 RmlC-like cupin domain SPYM18_RS04295 03cbb3c6dd5982c98e127efb6828b179 197 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 17 187 4.3E-38 T 23-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 SPYM18_RS03210 ecc3dfa7351b5730a86ea7d6b8081bec 125 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 4 101 7.5E-10 T 23-04-2016 IPR031807 HicB-like antitoxin of toxin-antitoxin system SPYM18_RS03210 ecc3dfa7351b5730a86ea7d6b8081bec 125 SUPERFAMILY SSF143100 1 53 1.01E-10 T 23-04-2016 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 PANTHER PTHR11804 145 596 1.5E-109 T 23-04-2016 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 Pfam PF01432 Peptidase family M3 202 581 1.6E-78 T 23-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 5 591 4.6E-174 T 23-04-2016 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 Gene3D G3DSA:3.40.390.10 322 422 2.2E-5 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 Gene3D G3DSA:1.10.287.830 179 225 2.3E-17 T 23-04-2016 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 SUPERFAMILY SSF55486 53 594 3.37E-121 T 23-04-2016 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 PANTHER PTHR11804:SF8 145 596 1.5E-109 T 23-04-2016 SPYM18_RS06075 d962481cbaa3645e028e405832836590 601 Pfam PF08439 Oligopeptidase F 112 181 2.1E-19 T 23-04-2016 IPR013647 Oligopeptidase F, N-terminal domain SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 SUPERFAMILY SSF48168 8 166 5.75E-47 T 23-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 560 582 - T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 91 163 2.7E-11 T 23-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Pfam PF02867 Ribonucleotide reductase, barrel domain 169 688 4.3E-139 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 95 692 8.2E-170 T 23-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PANTHER PTHR11573 48 693 2.7E-216 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 SUPERFAMILY SSF51998 167 693 7.02E-175 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 8 700 1.8E-293 T 23-04-2016 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 460 482 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 571 598 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 421 444 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 243 262 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 PRINTS PR01183 Ribonucleotide reductase large chain signature 488 511 4.4E-32 T 23-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Gene3D G3DSA:3.20.70.20 648 688 8.8E-55 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Gene3D G3DSA:3.20.70.20 571 616 8.8E-55 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Gene3D G3DSA:3.20.70.20 342 508 8.8E-55 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Gene3D G3DSA:3.20.70.20 100 289 8.8E-55 T 23-04-2016 SPYM18_RS02095 2e24c7701aecdcdd287bada5bad0195a 726 Pfam PF08343 Ribonucleotide reductase N-terminal 8 89 3.5E-23 T 23-04-2016 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 SUPERFAMILY SSF101473 4 200 1.01E-46 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 Pfam PF13684 Dihydroxyacetone kinase family 240 554 2.9E-127 T 23-04-2016 IPR033470 Uncharacterised protein, DhaK domain SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 554 1.7E-213 T 23-04-2016 IPR019986 DAK2 domain-containing protein YloV SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 SMART SM01121 240 554 1.1E-193 T 23-04-2016 IPR033470 Uncharacterised protein, DhaK domain SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 Pfam PF02734 DAK2 domain 34 198 4.6E-41 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 PANTHER PTHR33434 1 554 2.6E-251 T 23-04-2016 SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 PANTHER PTHR33434:SF4 1 554 2.6E-251 T 23-04-2016 SPYM18_RS08405 0a83bd8c45223eb29b55d19b87e92da3 554 SMART SM01120 34 199 1.4E-68 T 23-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 Gene3D G3DSA:3.40.50.1260 4 185 9.6E-68 T 23-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 316 341 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 373 390 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 174 196 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 350 361 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 197 216 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PRINTS PR00477 Phosphoglycerate kinase family signature 110 125 6.4E-92 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PANTHER PTHR11406 1 398 5.6E-201 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 397 39.446 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 23-04-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 Pfam PF00162 Phosphoglycerate kinase 6 387 1.2E-144 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 SUPERFAMILY SSF53748 3 397 4.36E-142 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 Gene3D G3DSA:3.40.50.1270 186 385 4.0E-76 T 23-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS08390 14c3ef6744c6a077a9734d5cfbbdd45c 398 PIRSF PIRSF000724 1 398 2.3E-130 T 23-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 SPYM18_RS07415 335e7a81e6f6a06f014dc079d73a52fb 329 PANTHER PTHR23024 91 326 1.9E-41 T 23-04-2016 SPYM18_RS07415 335e7a81e6f6a06f014dc079d73a52fb 329 Gene3D G3DSA:3.40.50.1820 90 326 2.9E-38 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS07415 335e7a81e6f6a06f014dc079d73a52fb 329 Pfam PF07859 alpha/beta hydrolase fold 107 305 3.8E-31 T 23-04-2016 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 SPYM18_RS07415 335e7a81e6f6a06f014dc079d73a52fb 329 PANTHER PTHR23024:SF47 91 326 1.9E-41 T 23-04-2016 SPYM18_RS07415 335e7a81e6f6a06f014dc079d73a52fb 329 SUPERFAMILY SSF53474 93 326 9.46E-36 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 PANTHER PTHR32502:SF3 5 188 3.7E-130 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 PANTHER PTHR32502:SF3 239 394 3.7E-130 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 Pfam PF01380 SIS domain 59 193 4.6E-12 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 SUPERFAMILY SSF53697 17 380 3.53E-50 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 PANTHER PTHR32502 5 188 3.7E-130 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 PANTHER PTHR32502 239 394 3.7E-130 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 Gene3D G3DSA:3.40.50.10490 213 382 3.0E-51 T 23-04-2016 SPYM18_RS03375 53eacef60f7d51e59ed2f53280f50c91 399 Gene3D G3DSA:3.40.50.10490 1 199 1.3E-74 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 Pfam PF01546 Peptidase family M20/M25/M40 87 465 4.7E-31 T 23-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 Gene3D G3DSA:3.40.630.10 385 468 1.3E-69 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 Gene3D G3DSA:3.40.630.10 5 189 1.3E-69 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 TIGRFAM TIGR01886 dipeptidase: dipeptidase PepV 3 469 1.4E-222 T 23-04-2016 IPR011291 Peptidase M20A, peptidase V KEGG: 00480+3.4.13.- SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 14 464 9.7E-175 T 23-04-2016 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 KEGG: 00480+3.4.13.- SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 PANTHER PTHR11014 261 469 3.0E-59 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 PANTHER PTHR11014 4 193 3.0E-59 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 117 156 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 Gene3D G3DSA:3.30.70.360 207 286 3.7E-31 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 SUPERFAMILY SSF55031 189 384 1.16E-53 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 SUPERFAMILY SSF53187 386 468 3.83E-68 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 SUPERFAMILY SSF53187 4 189 3.83E-68 T 23-04-2016 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 23-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 SPYM18_RS04515 cf07764c6abe2db387b6b44ae06feedd 469 Gene3D G3DSA:3.30.70.360 287 383 1.8E-37 T 23-04-2016 IPR011650 Peptidase M20, dimerisation domain SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Gene3D G3DSA:3.90.960.10 292 422 5.9E-32 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451:SF3 433 617 9.6E-131 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451:SF3 255 282 9.6E-131 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451:SF3 4 216 9.6E-131 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 4.76E-15 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 4.76E-15 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 4.76E-15 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 4.76E-15 T 23-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 SUPERFAMILY SSF52954 511 614 3.6E-24 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 94 493 3.8E-56 T 23-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 616 38.123 T 23-04-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 SUPERFAMILY SSF55681 9 244 3.64E-84 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 SUPERFAMILY SSF55681 441 524 3.64E-84 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Gene3D G3DSA:3.40.50.800 514 616 2.4E-24 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 216 5.0E-97 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 250 611 3.6E-93 T 23-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Gene3D G3DSA:3.30.930.10 1 228 1.1E-87 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Gene3D G3DSA:3.30.930.10 441 494 1.1E-87 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Pfam PF03129 Anticodon binding domain 522 611 5.6E-15 T 23-04-2016 IPR004154 Anticodon-binding SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451 433 617 9.6E-131 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451 255 282 9.6E-131 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 PANTHER PTHR11451 4 216 9.6E-131 T 23-04-2016 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 Pfam PF04073 Aminoacyl-tRNA editing domain 295 414 6.7E-25 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS08745 32f0aff6482607f67b4e57e6fd1d13c9 618 SUPERFAMILY SSF55826 256 423 1.57E-32 T 23-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 Gene3D G3DSA:1.10.10.10 124 221 9.8E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 PANTHER PTHR26402:SF518 2 222 3.0E-103 T 23-04-2016 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 2.1E-18 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 SMART SM00862 145 220 2.7E-17 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 SUPERFAMILY SSF52172 1 177 3.92E-35 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 SMART SM00448 2 112 9.8E-34 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 Gene3D G3DSA:3.40.50.2300 2 120 8.8E-34 T 23-04-2016 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 Pfam PF00072 Response regulator receiver domain 4 112 7.0E-22 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS05135 220cc0eef7f7aaa811c546474bb5788e 224 PANTHER PTHR26402 2 222 3.0E-103 T 23-04-2016 SPYM18_RS06570 64787d260f04913ced1dd42142759fde 76 Pfam PF08796 Protein of unknown function (DUF1797) 8 75 3.5E-23 T 23-04-2016 IPR014904 Protein of unknown function DUF1797 SPYM18_RS06570 64787d260f04913ced1dd42142759fde 76 SUPERFAMILY SSF143567 3 76 1.44E-23 T 23-04-2016 SPYM18_RS06570 64787d260f04913ced1dd42142759fde 76 PIRSF PIRSF037356 1 76 8.8E-32 T 23-04-2016 IPR014904 Protein of unknown function DUF1797 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 Gene3D G3DSA:3.40.50.2300 4 131 8.2E-35 T 23-04-2016 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 Pfam PF12833 Helix-turn-helix domain 164 242 1.0E-20 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 SMART SM00342 158 241 4.3E-30 T 23-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 SUPERFAMILY SSF52172 3 144 3.13E-33 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 SUPERFAMILY SSF46689 149 192 7.62E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 SMART SM00448 2 116 1.8E-31 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 225 241 8.5E-8 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 210 225 8.5E-8 T 23-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 Gene3D G3DSA:1.10.10.60 196 244 5.3E-18 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 195 237 - T 23-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 Pfam PF00072 Response regulator receiver domain 5 115 5.6E-29 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 PANTHER PTHR26402 2 122 2.6E-38 T 23-04-2016 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 SUPERFAMILY SSF46689 195 243 2.73E-14 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06770 07854d03af89eaeb05f9b5ceed47c5f7 246 Gene3D G3DSA:1.10.10.60 141 195 7.3E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS09380 8ff6ad2655547f6211742765512e6257 330 Gene3D G3DSA:3.30.420.10 179 314 4.1E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS09380 8ff6ad2655547f6211742765512e6257 330 Pfam PF13936 Helix-turn-helix domain 8 51 1.2E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS09380 8ff6ad2655547f6211742765512e6257 330 SUPERFAMILY SSF53098 176 314 6.07E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS09380 8ff6ad2655547f6211742765512e6257 330 PANTHER PTHR10948 4 328 5.4E-83 T 23-04-2016 SPYM18_RS09380 8ff6ad2655547f6211742765512e6257 330 Gene3D G3DSA:1.10.10.60 7 46 5.9E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PANTHER PTHR11751 119 143 1.5E-25 T 23-04-2016 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PANTHER PTHR11751 6 71 1.5E-25 T 23-04-2016 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 SMART SM00866 91 231 1.9E-32 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 Gene3D G3DSA:3.40.1410.10 66 236 5.1E-52 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 SMART SM00345 11 69 1.0E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 5.4E-14 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 SUPERFAMILY SSF64288 57 237 5.34E-47 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.8E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.8E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 SUPERFAMILY SSF46785 3 79 6.92E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PANTHER PTHR11751:SF333 119 143 1.5E-25 T 23-04-2016 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 PANTHER PTHR11751:SF333 6 71 1.5E-25 T 23-04-2016 SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 Gene3D G3DSA:1.10.10.10 3 65 1.2E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03370 bf21a795862b49b81974c365a252f004 240 Pfam PF07702 UTRA domain 92 231 7.7E-35 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 PANTHER PTHR10683 1 212 5.4E-76 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 SUPERFAMILY SSF51569 1 211 2.09E-75 T 23-04-2016 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 Hamap MF_00494 Probable transaldolase [tal]. 1 214 46.218 T 23-04-2016 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 Gene3D G3DSA:3.20.20.70 1 212 5.8E-70 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 211 4.9E-84 T 23-04-2016 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 ProSitePatterns PS00958 Transaldolase active site. 80 96 - T 23-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 23-04-2016 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS07265 fd07cec9c86bc0d324eb0a663e80b5c1 214 Pfam PF00923 Transaldolase 3 200 2.4E-54 T 23-04-2016 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 227 3.8E-22 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 253 545 9.3E-128 T 23-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 SUPERFAMILY SSF52009 127 243 4.58E-35 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 3.7E-30 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 569 2.4E-225 T 23-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 SUPERFAMILY SSF47831 24 145 4.84E-34 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Gene3D G3DSA:3.20.20.60 259 575 6.3E-113 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PANTHER PTHR22931 13 29 1.3E-203 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PANTHER PTHR22931 50 554 1.3E-203 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PIRSF PIRSF000732 1 577 4.8E-210 T 23-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 1.8E-32 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 1.8E-32 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 1.8E-32 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 1.8E-32 T 23-04-2016 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 23-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 SUPERFAMILY SSF51621 252 553 1.68E-108 T 23-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 23-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Gene3D G3DSA:3.50.30.10 136 258 5.3E-42 T 23-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 SPYM18_RS05990 4b88100a9f4debfff1816bb44ece26f6 577 Gene3D G3DSA:1.10.274.10 24 135 5.4E-39 T 23-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-7 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.4E-18 T 23-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 Gene3D G3DSA:1.10.10.10 1 84 3.6E-24 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 PANTHER PTHR30346:SF0 1 293 1.9E-43 T 23-04-2016 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 PANTHER PTHR30346 1 293 1.9E-43 T 23-04-2016 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 SUPERFAMILY SSF46785 1 84 2.5E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 Pfam PF03466 LysR substrate binding domain 99 295 7.8E-12 T 23-04-2016 IPR005119 LysR, substrate-binding SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 Gene3D G3DSA:3.40.190.10 96 203 3.2E-9 T 23-04-2016 SPYM18_RS03815 9b130075d94c3b83a9d27ca8b7746009 304 SUPERFAMILY SSF53850 98 299 1.05E-15 T 23-04-2016 SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 SMART SM00986 25 182 5.9E-20 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 Pfam PF03167 Uracil DNA glycosylase superfamily 28 178 6.3E-18 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 SUPERFAMILY SSF52141 1 188 2.85E-45 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 Gene3D G3DSA:3.40.470.10 2 189 6.2E-32 T 23-04-2016 IPR005122 Uracil-DNA glycosylase-like SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 SMART SM00987 25 182 5.9E-20 T 23-04-2016 SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 PANTHER PTHR42160:SF1 1 191 2.7E-87 T 23-04-2016 SPYM18_RS02250 4b65b8a75d19848342f76d26dda1050a 191 PANTHER PTHR42160 1 191 2.7E-87 T 23-04-2016 SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Gene3D G3DSA:3.30.1270.10 210 235 3.6E-34 T 23-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Gene3D G3DSA:3.30.1270.10 81 131 3.6E-34 T 23-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 SUPERFAMILY SSF75625 1 235 6.41E-79 T 23-04-2016 IPR029072 YebC-like SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 PANTHER PTHR12532:SF4 1 237 1.9E-147 T 23-04-2016 SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 64.812 T 23-04-2016 IPR026562 Probable transcriptional regulatory protein YeeN SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Pfam PF01709 Transcriptional regulator 4 235 1.5E-79 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 2.2E-68 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Gene3D G3DSA:1.10.10.200 1 77 6.9E-29 T 23-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 PANTHER PTHR12532 1 237 1.9E-147 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Gene3D G3DSA:3.30.70.980 132 202 1.2E-23 T 23-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 SPYM18_RS01440 68bb808e737252cf5947297bda621e2c 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 30.514 T 23-04-2016 IPR002876 Transcriptional regulator TACO1-like SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PANTHER PTHR24423 209 499 1.0E-53 T 23-04-2016 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PANTHER PTHR24423 60 88 1.0E-53 T 23-04-2016 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 Gene3D G3DSA:1.10.287.130 260 324 3.8E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 Gene3D G3DSA:3.30.565.10 325 498 1.2E-37 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SMART SM00304 215 269 1.6E-8 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 Pfam PF00672 HAMP domain 196 265 1.3E-10 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SUPERFAMILY SSF47384 254 335 2.16E-17 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SMART SM00387 381 496 1.2E-28 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SUPERFAMILY SSF158472 215 266 1.16E-5 T 23-04-2016 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SMART SM00388 270 337 1.5E-15 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 495 1.9E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 SUPERFAMILY SSF55874 326 497 1.11E-33 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 474 1.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 447 1.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 1.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 PRINTS PR00344 Bacterial sensor protein C-terminal signature 480 493 1.9E-13 T 23-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 SPYM18_RS01510 b7b4dfd702a1f1b1ce5e7fc8a5ab0ffb 500 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 334 1.1E-13 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS01575 0dafcc672a9b69d31be8318f6ce34179 239 SMART SM01040 11 97 9.5E-46 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS01575 0dafcc672a9b69d31be8318f6ce34179 239 Pfam PF02498 BRO family, N-terminal domain 11 97 1.3E-32 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS01575 0dafcc672a9b69d31be8318f6ce34179 239 PANTHER PTHR36180 5 143 2.1E-42 T 23-04-2016 SPYM18_RS01575 0dafcc672a9b69d31be8318f6ce34179 239 Pfam PF10552 ORF6C domain 115 227 2.2E-34 T 23-04-2016 IPR018878 ORF6C domain SPYM18_RS01575 0dafcc672a9b69d31be8318f6ce34179 239 PANTHER PTHR36180:SF2 5 143 2.1E-42 T 23-04-2016 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 SUPERFAMILY SSF89623 1 152 4.32E-49 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 PANTHER PTHR30345:SF4 1 171 3.1E-130 T 23-04-2016 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 TIGRFAM TIGR01119 lacB: galactose-6-phosphate isomerase, LacB subunit 1 171 4.5E-103 T 23-04-2016 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 Hamap MF_01556 Galactose-6-phosphate isomerase subunit LacB [lacB]. 1 171 47.78 T 23-04-2016 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 Gene3D G3DSA:3.40.1400.10 1 155 4.8E-53 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 145 1.7E-36 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 PANTHER PTHR30345 1 171 3.1E-130 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 Pfam PF02502 Ribose/Galactose Isomerase 3 141 1.3E-40 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS07370 eaaac29a5798cbe0c75621d014b7a5c9 171 PIRSF PIRSF005384 1 148 4.4E-49 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 PANTHER PTHR19211 6 574 4.4E-189 T 23-04-2016 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Pfam PF12848 ABC transporter 223 295 2.7E-8 T 23-04-2016 IPR032781 ABC-transporter extension domain SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Gene3D G3DSA:3.40.50.300 314 535 1.2E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Pfam PF00005 ABC transporter 333 466 6.7E-22 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Pfam PF00005 ABC transporter 20 184 2.4E-21 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Gene3D G3DSA:3.40.50.300 6 280 4.2E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 Pfam PF16326 ABC transporter C-terminal domain 556 621 6.9E-14 T 23-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 SUPERFAMILY SSF52540 6 239 1.69E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 SMART SM00382 341 520 1.1E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 SMART SM00382 28 229 2.3E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03990 bbb7ea95b7c7c732b0ba720fa96169c4 625 SUPERFAMILY SSF52540 307 524 1.8E-45 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05010 3e89f4d7451a43fb74fdd8bd16748b8a 288 PANTHER PTHR10534 1 256 1.6E-23 T 23-04-2016 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 SPYM18_RS05010 3e89f4d7451a43fb74fdd8bd16748b8a 288 Gene3D G3DSA:3.40.1190.20 1 265 2.6E-47 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS05010 3e89f4d7451a43fb74fdd8bd16748b8a 288 SUPERFAMILY SSF53613 1 273 9.2E-44 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS05010 3e89f4d7451a43fb74fdd8bd16748b8a 288 Pfam PF08543 Phosphomethylpyrimidine kinase 71 255 7.2E-18 T 23-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 SPYM18_RS05010 3e89f4d7451a43fb74fdd8bd16748b8a 288 PANTHER PTHR10534:SF0 1 256 1.6E-23 T 23-04-2016 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 178 4.6E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 7.5E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 7.5E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 7.5E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 7.5E-14 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 Gene3D G3DSA:1.10.150.240 17 80 4.1E-27 T 23-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 PANTHER PTHR18901 1 207 4.5E-43 T 23-04-2016 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.0E-35 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 Gene3D G3DSA:3.40.50.1000 1 16 2.7E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 Gene3D G3DSA:3.40.50.1000 89 207 2.7E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 183 2.9E-16 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS03000 e2333092dc544de75c1e7a15545c50e7 216 SUPERFAMILY SSF56784 1 207 4.96E-48 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 Pfam PF00255 Glutathione peroxidase 4 111 1.8E-39 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 PRINTS PR01011 Glutathione peroxidase family signature 57 73 5.4E-17 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 PRINTS PR01011 Glutathione peroxidase family signature 22 39 5.4E-17 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 PRINTS PR01011 Glutathione peroxidase family signature 122 131 5.4E-17 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 PIRSF PIRSF000303 1 162 4.9E-64 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 SUPERFAMILY SSF52833 3 158 1.64E-57 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 23-04-2016 IPR029760 Glutathione peroxidase conserved site SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 PANTHER PTHR11592 1 161 1.1E-82 T 23-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 SPYM18_RS02880 994715b7f2e1e1aa7609d9c155dff756 167 Gene3D G3DSA:3.40.30.10 3 159 1.1E-69 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 PIRSF PIRSF037785 21 202 1.0E-76 T 23-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 SUPERFAMILY SSF52980 32 195 2.65E-62 T 23-04-2016 IPR011335 Restriction endonuclease type II-like SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 202 99.4 T 23-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 Gene3D G3DSA:3.40.1350.10 31 196 5.8E-71 T 23-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 Pfam PF03838 Recombination protein U 30 192 1.2E-62 T 23-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 TIGRFAM TIGR00648 recU: recombination protein U 29 194 3.7E-61 T 23-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 SPYM18_RS07155 eeec481e98ea0c62c617bee321c886c5 202 PANTHER PTHR41275 1 202 3.8E-92 T 23-04-2016 SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 226 6.9E-64 T 23-04-2016 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154|UniPathway: UPA00904 SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 SUPERFAMILY SSF53167 1 229 1.96E-67 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 Pfam PF01048 Phosphorylase superfamily 2 226 1.3E-46 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 Gene3D G3DSA:3.40.50.1580 1 229 5.0E-71 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 PANTHER PTHR21234 1 231 5.6E-49 T 23-04-2016 IPR018017 Nucleoside phosphorylase SPYM18_RS02155 daaf4579858ae51b811b00f4c09fa803 231 PANTHER PTHR21234:SF16 1 231 5.6E-49 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 5.0E-70 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF54980 402 479 7.19E-25 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF52540 6 280 1.19E-111 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Pfam PF03764 Elongation factor G, domain IV 477 596 4.3E-46 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.3E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.3E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.3E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.3E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.3E-16 T 23-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF50447 303 399 1.16E-34 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF50447 246 273 1.16E-34 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Pfam PF00679 Elongation factor G C-terminus 599 684 6.1E-30 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Gene3D G3DSA:3.30.230.10 482 594 2.6E-49 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 23-04-2016 IPR031157 Tr-type G domain, conserved site SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Gene3D G3DSA:3.30.70.870 404 478 2.2E-37 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF54211 477 597 7.59E-44 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115:SF66 1 177 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115:SF66 301 689 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115:SF66 253 281 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 23-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 5.7E-15 T 23-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 109.489 T 23-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SMART SM00838 598 685 1.4E-50 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115 1 177 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115 301 689 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 PANTHER PTHR23115 253 281 0.0 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Gene3D G3DSA:3.40.50.300 7 285 2.4E-108 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Gene3D G3DSA:2.40.30.10 303 403 1.0E-37 T 23-04-2016 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SMART SM00889 478 596 1.9E-72 T 23-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 SUPERFAMILY SSF54980 601 688 8.15E-30 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 2.4E-42 T 23-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Gene3D G3DSA:3.30.70.240 595 689 3.4E-33 T 23-04-2016 IPR000640 Translation elongation factor EFG, V domain SPYM18_RS01265 31d9ce374c601be7112d34bef3b09645 692 Pfam PF14492 Elongation Factor G, domain II 402 475 2.7E-33 T 23-04-2016 IPR009022 Elongation factor G, III-V domain SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Gene3D G3DSA:1.20.1570.10 208 246 2.1E-49 T 23-04-2016 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Gene3D G3DSA:1.20.1570.10 283 340 2.1E-49 T 23-04-2016 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Hamap MF_01567 UPF0371 protein . 2 494 62.608 T 23-04-2016 IPR014999 Uncharacterised protein family UPF0371 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Gene3D G3DSA:3.10.630.10 1 207 4.3E-127 T 23-04-2016 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Gene3D G3DSA:3.10.630.10 253 282 4.3E-127 T 23-04-2016 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 PIRSF PIRSF033132 2 494 1.1E-273 T 23-04-2016 IPR014999 Uncharacterised protein family UPF0371 SPYM18_RS05870 c65329cead40c4cb9e6452282eef001b 494 Pfam PF08903 Domain of unknown function (DUF1846) 4 492 1.3E-241 T 23-04-2016 IPR014999 Uncharacterised protein family UPF0371 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 Hamap MF_00551 Uridine kinase [udk]. 2 206 43.228 T 23-04-2016 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PANTHER PTHR10285 2 208 7.9E-87 T 23-04-2016 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 Gene3D G3DSA:3.40.50.300 4 206 1.8E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 SUPERFAMILY SSF52540 2 197 3.64E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 191 1.6E-46 T 23-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 80 95 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 172 185 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 150 161 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 136 146 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 35 46 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 PRINTS PR00988 Uridine kinase signature 5 22 6.0E-39 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS05970 6081fd4809c092e829fd86f5693aea14 208 TIGRFAM TIGR00235 udk: uridine kinase 4 205 6.6E-87 T 23-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 SPYM18_RS03640 7b9101db99eee31914471bfe578fda44 112 Pfam PF01883 Domain of unknown function DUF59 16 89 1.1E-22 T 23-04-2016 IPR002744 Domain of unknown function DUF59 SPYM18_RS03640 7b9101db99eee31914471bfe578fda44 112 PANTHER PTHR13696:SF62 15 109 7.1E-22 T 23-04-2016 SPYM18_RS03640 7b9101db99eee31914471bfe578fda44 112 SUPERFAMILY SSF117916 15 110 2.84E-31 T 23-04-2016 SPYM18_RS03640 7b9101db99eee31914471bfe578fda44 112 PANTHER PTHR13696 15 109 7.1E-22 T 23-04-2016 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 113 128 3.0E-14 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 3.0E-14 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 3.0E-14 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 PANTHER PTHR11717:SF7 1 144 2.1E-38 T 23-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 PANTHER PTHR11717 1 144 2.1E-38 T 23-04-2016 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 SUPERFAMILY SSF52788 1 140 2.35E-40 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 Gene3D G3DSA:3.40.50.270 1 143 7.8E-42 T 23-04-2016 SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 SMART SM00226 2 139 1.7E-29 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPYM18_RS00335 7bfde09767b7ea74c7919f4aa7d846c0 145 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 137 3.5E-30 T 23-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 SUPERFAMILY SSF52540 9 379 2.54E-54 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 PANTHER PTHR30121 10 440 3.0E-158 T 23-04-2016 SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 PANTHER PTHR30121:SF3 10 440 3.0E-158 T 23-04-2016 SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 Pfam PF05872 Bacterial protein of unknown function (DUF853) 4 499 1.8E-246 T 23-04-2016 IPR033186 Helicase HerA-like C-terminal SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 Gene3D G3DSA:3.40.50.300 8 106 1.0E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02410 da1dae3593de37b5a46faa2023b11649 500 Gene3D G3DSA:3.40.50.300 202 381 1.0E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 90 3.2E-7 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 SUPERFAMILY SSF52374 24 210 1.47E-50 T 23-04-2016 SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 28 209 4.4E-54 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 24 210 29.988 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 Gene3D G3DSA:3.40.50.620 21 210 1.7E-63 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 Pfam PF01467 Cytidylyltransferase-like 28 183 7.5E-34 T 23-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 SPYM18_RS01415 c9a9f04e31e3eee5501c89ba591fd80c 210 PANTHER PTHR12039 3 210 5.3E-52 T 23-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 Gene3D G3DSA:3.30.390.30 340 440 3.1E-9 T 23-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 Gene3D G3DSA:3.50.50.60 115 319 6.7E-36 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 308 5.8E-37 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PANTHER PTHR22912:SF154 6 418 8.3E-40 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 SUPERFAMILY SSF51905 4 320 8.39E-32 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 8.9E-14 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 8.9E-14 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 8.9E-14 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 8.9E-14 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PANTHER PTHR22912 6 418 8.3E-40 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 2.4E-11 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 287 2.4E-11 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 2.4E-11 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 2.4E-11 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 383 398 2.4E-11 T 23-04-2016 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 Gene3D G3DSA:3.50.50.60 6 114 1.4E-8 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS07275 3858c5959c7c53c4d2043b8055371cfd 448 SUPERFAMILY SSF55424 330 441 3.09E-14 T 23-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 SPYM18_RS03260 43a5d5035c507c7fea8446817a60e47b 100 Pfam PF05135 Phage gp6-like head-tail connector protein 7 94 3.1E-11 T 23-04-2016 IPR021146 Phage gp6-like head-tail connector protein SPYM18_RS03260 43a5d5035c507c7fea8446817a60e47b 100 TIGRFAM TIGR01560 put_DNA_pack: uncharacterized phage protein (possible DNA packaging) 8 98 2.2E-34 T 23-04-2016 IPR006450 Phage protein of unkonwn function SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 65 119 2.2E-5 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 SUPERFAMILY SSF56349 65 370 1.03E-46 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 Gene3D G3DSA:1.10.150.130 65 162 1.2E-11 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 Gene3D G3DSA:1.10.443.10 173 374 2.1E-33 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 Pfam PF00589 Phage integrase family 173 367 2.1E-23 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 PANTHER PTHR30349 65 378 7.0E-33 T 23-04-2016 SPYM18_RS06485 5304cbbf6d15a9004686bc44fa3140e9 380 PANTHER PTHR30349:SF20 65 378 7.0E-33 T 23-04-2016 SPYM18_RS04475 87e9a7b16def92d34048b9e9ba5bfb64 269 PANTHER PTHR32502:SF8 9 263 1.6E-36 T 23-04-2016 SPYM18_RS04475 87e9a7b16def92d34048b9e9ba5bfb64 269 Pfam PF03609 PTS system sorbose-specific iic component 7 235 8.7E-61 T 23-04-2016 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 SPYM18_RS04475 87e9a7b16def92d34048b9e9ba5bfb64 269 PANTHER PTHR32502 9 263 1.6E-36 T 23-04-2016 SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 PANTHER PTHR32319:SF3 4 100 1.6E-30 T 23-04-2016 SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 Pfam PF13275 S4 domain 4 66 5.0E-22 T 23-04-2016 SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 PANTHER PTHR32319 4 100 1.6E-30 T 23-04-2016 SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 61 1.7E-26 T 23-04-2016 IPR014330 RNA-binding S4-related,YaaA SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 Gene3D G3DSA:3.10.290.10 3 66 2.7E-18 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS09575 9dc167331ca60fd2254ecb746a2e0208 137 SUPERFAMILY SSF55174 3 67 2.5E-14 T 23-04-2016 SPYM18_RS03835 f97add3859f7a572091e7940073fd1b2 419 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 SPYM18_RS03835 f97add3859f7a572091e7940073fd1b2 419 PANTHER PTHR11119 7 418 2.5E-147 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS03835 f97add3859f7a572091e7940073fd1b2 419 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 412 2.5E-118 T 23-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 SPYM18_RS03835 f97add3859f7a572091e7940073fd1b2 419 Pfam PF00860 Permease family 19 390 3.5E-88 T 23-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 SPYM18_RS03835 f97add3859f7a572091e7940073fd1b2 419 PANTHER PTHR11119:SF49 7 418 2.5E-147 T 23-04-2016 SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 2.4E-61 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 2.0E-52 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 1.3E-25 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 PANTHER PTHR10000:SF23 1 270 4.1E-96 T 23-04-2016 SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 SUPERFAMILY SSF56784 1 269 1.01E-63 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 PANTHER PTHR10000 1 270 4.1E-96 T 23-04-2016 SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 Gene3D G3DSA:3.40.50.1000 1 73 7.2E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS07815 84a145371d5c733eccccfd37d082572a 270 Gene3D G3DSA:3.40.50.1000 171 270 7.2E-52 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 SUPERFAMILY SSF52317 2 87 3.25E-17 T 23-04-2016 IPR029062 Class I glutamine amidotransferase-like SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 PANTHER PTHR30237:SF3 1 235 1.8E-70 T 23-04-2016 SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 PANTHER PTHR30237 1 235 1.8E-70 T 23-04-2016 SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 SUPERFAMILY SSF141986 90 236 3.14E-36 T 23-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 Gene3D G3DSA:3.50.30.60 110 236 1.1E-35 T 23-04-2016 IPR027461 LD-carboxypeptidase A, C-terminal domain SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 Pfam PF02016 LD-carboxypeptidase 2 235 4.2E-51 T 23-04-2016 IPR003507 Peptidase family S66 SPYM18_RS02700 205630cf54567c9786bb3a47d0d77832 238 Gene3D G3DSA:3.40.50.10740 1 61 1.7E-16 T 23-04-2016 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 251 5.8E-61 T 23-04-2016 SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.3E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 1.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 Gene3D G3DSA:3.40.50.720 3 252 1.3E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 SUPERFAMILY SSF51735 3 252 1.71E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PANTHER PTHR24322:SF347 7 134 8.0E-66 T 23-04-2016 SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PANTHER PTHR24322:SF347 150 182 8.0E-66 T 23-04-2016 SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PANTHER PTHR24322 7 134 8.0E-66 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 PANTHER PTHR24322 150 182 8.0E-66 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS03030 ab1b9bf428f189ec43a6ab4d6f7e17d2 254 TIGRFAM TIGR02415 23BDH: acetoin reductases 3 253 1.8E-105 T 23-04-2016 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 Gene3D G3DSA:3.40.50.300 340 552 8.6E-51 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 SUPERFAMILY SSF90123 14 322 3.53E-38 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 PANTHER PTHR24222 5 554 3.1E-93 T 23-04-2016 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 Gene3D G3DSA:1.20.1560.10 14 322 4.1E-29 T 23-04-2016 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 PANTHER PTHR24222:SF26 5 554 3.1E-93 T 23-04-2016 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 SUPERFAMILY SSF52540 336 553 2.39E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 Pfam PF00664 ABC transporter transmembrane region 65 289 1.4E-13 T 23-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 Pfam PF00005 ABC transporter 357 504 9.7E-26 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08035 a71bfc173150da3884bec25ed45da96d 556 SMART SM00382 365 549 2.5E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS06265 850dbc35d4913d34bec9fcdac4b25300 333 Pfam PF07212 Hyaluronidase protein (HylP) 56 333 6.4E-151 T 23-04-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 SPYM18_RS06265 850dbc35d4913d34bec9fcdac4b25300 333 SUPERFAMILY SSF69349 7 331 6.36E-122 T 23-04-2016 SPYM18_RS08905 75eb614632182b61b4e54fa9bb4255f2 273 PANTHER PTHR30465 2 272 2.2E-64 T 23-04-2016 SPYM18_RS08905 75eb614632182b61b4e54fa9bb4255f2 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 261 1.5E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08905 75eb614632182b61b4e54fa9bb4255f2 273 PANTHER PTHR30465:SF50 2 272 2.2E-64 T 23-04-2016 SPYM18_RS08905 75eb614632182b61b4e54fa9bb4255f2 273 Gene3D G3DSA:1.10.3720.10 64 264 1.0E-20 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08905 75eb614632182b61b4e54fa9bb4255f2 273 SUPERFAMILY SSF161098 66 256 1.96E-24 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 PANTHER PTHR11358 49 326 1.4E-65 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 PIRSF PIRSF036979 27 328 6.9E-38 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 PANTHER PTHR11358:SF35 49 326 1.4E-65 T 23-04-2016 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 Hamap MF_00737 Formimidoylglutamase [hutG]. 8 322 39.487 T 23-04-2016 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8|UniPathway: UPA00379 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 Pfam PF00491 Arginase family 47 319 3.1E-55 T 23-04-2016 IPR006035 Ureohydrolase GO:0046872 Reactome: REACT_13 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 SUPERFAMILY SSF52768 19 326 2.52E-73 T 23-04-2016 SPYM18_RS09200 63ee53ef3d3a8ec12ca80253406acf62 328 Gene3D G3DSA:3.40.800.10 10 327 1.9E-92 T 23-04-2016 IPR023696 Ureohydrolase domain SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 Gene3D G3DSA:3.10.580.10 7 148 4.2E-28 T 23-04-2016 SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 SMART SM00116 23 71 12.0 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 SMART SM00116 92 138 0.0031 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 PANTHER PTHR11911 22 151 3.9E-28 T 23-04-2016 SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 Pfam PF00571 CBS domain 34 70 2.9E-5 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 Pfam PF00571 CBS domain 85 137 4.0E-9 T 23-04-2016 IPR000644 CBS domain SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 SUPERFAMILY SSF54631 15 138 3.28E-25 T 23-04-2016 SPYM18_RS01890 70065aa34032c85fb106bbf072c86b69 153 PANTHER PTHR11911:SF103 22 151 3.9E-28 T 23-04-2016 SPYM18_RS09045 0e5dcbebaefdfa12639dabf4cbb5a5d9 434 PANTHER PTHR33989:SF5 1 428 2.0E-302 T 23-04-2016 SPYM18_RS09045 0e5dcbebaefdfa12639dabf4cbb5a5d9 434 PIRSF PIRSF006351 1 434 3.1E-127 T 23-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 SPYM18_RS09045 0e5dcbebaefdfa12639dabf4cbb5a5d9 434 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 11 429 5.5E-112 T 23-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPYM18_RS09045 0e5dcbebaefdfa12639dabf4cbb5a5d9 434 PANTHER PTHR33989 1 428 2.0E-302 T 23-04-2016 SPYM18_RS09045 0e5dcbebaefdfa12639dabf4cbb5a5d9 434 Pfam PF02378 Phosphotransferase system, EIIC 26 356 2.2E-63 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 SMART SM00354 6 76 1.2E-37 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 Gene3D G3DSA:1.10.260.40 7 58 1.3E-27 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 SUPERFAMILY SSF53822 66 333 1.57E-66 T 23-04-2016 IPR028082 Periplasmic binding protein-like I SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 Gene3D G3DSA:3.40.50.2300 178 313 1.5E-32 T 23-04-2016 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 7.1E-22 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 SUPERFAMILY SSF47413 6 64 1.61E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 Gene3D G3DSA:3.40.50.2300 59 177 1.7E-42 T 23-04-2016 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 PANTHER PTHR30146 6 333 1.2E-116 T 23-04-2016 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 5 333 1.2E-162 T 23-04-2016 IPR006377 Catabolite control protein A GO:0006355 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 PANTHER PTHR30146:SF4 6 333 1.2E-116 T 23-04-2016 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 Pfam PF13377 Periplasmic binding protein-like domain 176 332 3.0E-24 T 23-04-2016 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 8.1E-7 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS02480 f3e3cfb67ab56edcfb0c9ff8f56b9ccf 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 8.1E-7 T 23-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 SPYM18_RS08400 2dbbf6d56b4987fea82bd87f9fdab129 296 Pfam PF01145 SPFH domain / Band 7 family 25 197 3.5E-27 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS08400 2dbbf6d56b4987fea82bd87f9fdab129 296 SMART SM00244 21 181 1.9E-28 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS08400 2dbbf6d56b4987fea82bd87f9fdab129 296 PANTHER PTHR10264 5 293 9.3E-141 T 23-04-2016 IPR001972 Stomatin family GO:0016020 SPYM18_RS08400 2dbbf6d56b4987fea82bd87f9fdab129 296 SUPERFAMILY SSF117892 57 187 1.57E-25 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS08400 2dbbf6d56b4987fea82bd87f9fdab129 296 PANTHER PTHR10264:SF84 5 293 9.3E-141 T 23-04-2016 SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 PANTHER PTHR31727 52 212 3.7E-34 T 23-04-2016 SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 Gene3D G3DSA:3.10.129.10 150 240 4.0E-26 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 SUPERFAMILY SSF54637 1 146 5.11E-33 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 Pfam PF01643 Acyl-ACP thioesterase 2 240 1.0E-71 T 23-04-2016 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 SUPERFAMILY SSF54637 150 239 1.18E-23 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS04430 57cb3314cb3d8fae5396e5f7320c0b94 250 Gene3D G3DSA:3.10.129.10 2 145 1.1E-27 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 Pfam PF00654 Voltage gated chloride channel 93 424 1.6E-53 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 PRINTS PR00762 Chloride channel signature 397 416 1.5E-6 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 PRINTS PR00762 Chloride channel signature 183 202 1.5E-6 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 PRINTS PR00762 Chloride channel signature 132 151 1.5E-6 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 PRINTS PR00762 Chloride channel signature 379 395 1.5E-6 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 SUPERFAMILY SSF81340 26 432 7.85E-68 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 PANTHER PTHR11689 139 421 9.1E-12 T 23-04-2016 SPYM18_RS06015 27256c3bbe4f2337a9d63ce8ae6a4a4f 437 Gene3D G3DSA:1.10.3080.10 31 424 5.1E-55 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 SUPERFAMILY SSF55174 3 201 9.16E-68 T 23-04-2016 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 23-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 1.4E-23 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 35.121 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 PANTHER PTHR11831:SF4 1 199 6.6E-83 T 23-04-2016 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 Pfam PF01479 S4 domain 93 140 2.0E-22 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 3.2E-76 T 23-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 SMART SM00363 93 157 7.7E-21 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 Gene3D G3DSA:3.10.290.10 97 192 7.2E-35 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 PANTHER PTHR11831 1 199 6.6E-83 T 23-04-2016 IPR022801 Ribosomal protein S4/S9 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 SMART SM01390 3 92 2.6E-39 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 SPYM18_RS09470 8274242e02c6951cfe14732610089c7b 203 Gene3D G3DSA:1.10.1050.10 1 96 4.3E-37 T 23-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 SPYM18_RS07935 4c371fefd90e643dddebd344cddfe870 247 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 89 223 1.2E-36 T 23-04-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 SPYM18_RS07935 4c371fefd90e643dddebd344cddfe870 247 PANTHER PTHR34385 62 245 8.0E-35 T 23-04-2016 SPYM18_RS07935 4c371fefd90e643dddebd344cddfe870 247 Gene3D G3DSA:3.30.1380.10 114 176 3.8E-5 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain SPYM18_RS07935 4c371fefd90e643dddebd344cddfe870 247 SUPERFAMILY SSF55166 83 230 3.92E-24 T 23-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain SPYM18_RS07935 4c371fefd90e643dddebd344cddfe870 247 PANTHER PTHR34385:SF1 62 245 8.0E-35 T 23-04-2016 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 PANTHER PTHR10362:SF7 3 482 2.1E-231 T 23-04-2016 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 4 505 46.661 T 23-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 Gene3D G3DSA:1.10.275.10 3 198 2.8E-82 T 23-04-2016 IPR024083 Fumarase/histidase, N-terminal SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 PANTHER PTHR10362 3 482 2.1E-231 T 23-04-2016 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 23-04-2016 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 5 508 1.7E-195 T 23-04-2016 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|UniPathway: UPA00379 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 Gene3D G3DSA:1.20.200.10 199 508 2.7E-122 T 23-04-2016 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 SUPERFAMILY SSF48557 2 482 4.08E-192 T 23-04-2016 IPR008948 L-Aspartase-like GO:0003824 SPYM18_RS09195 4e0f6c709f37bfc2e07b724eb5e48a00 513 Pfam PF00221 Aromatic amino acid lyase 12 470 3.8E-196 T 23-04-2016 IPR001106 Aromatic amino acid lyase SPYM18_RS08410 b9847cc6ed21bba2aecd275ef411eb0a 121 PANTHER PTHR34297 1 121 1.4E-46 T 23-04-2016 SPYM18_RS08410 b9847cc6ed21bba2aecd275ef411eb0a 121 Pfam PF03780 Asp23 family, cell envelope-related function 10 116 5.9E-31 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 SPYM18_RS08410 b9847cc6ed21bba2aecd275ef411eb0a 121 PANTHER PTHR34297:SF2 1 121 1.4E-46 T 23-04-2016 SPYM18_RS05495 2e55c935537e9115e174c2d9d9863f1a 247 Pfam PF03374 Phage antirepressor protein KilAC domain 152 246 7.5E-22 T 23-04-2016 IPR005039 Antirepressor protein, C-terminal GO:0003677 SPYM18_RS05495 2e55c935537e9115e174c2d9d9863f1a 247 Pfam PF02498 BRO family, N-terminal domain 13 98 7.7E-22 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS05495 2e55c935537e9115e174c2d9d9863f1a 247 SMART SM01040 13 98 2.5E-35 T 23-04-2016 IPR003497 BRO N-terminal domain SPYM18_RS05495 2e55c935537e9115e174c2d9d9863f1a 247 PANTHER PTHR36180:SF2 3 179 1.7E-28 T 23-04-2016 SPYM18_RS05495 2e55c935537e9115e174c2d9d9863f1a 247 PANTHER PTHR36180 3 179 1.7E-28 T 23-04-2016 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 Gene3D G3DSA:1.10.3080.10 17 400 4.4E-37 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 SUPERFAMILY SSF81340 11 404 1.29E-69 T 23-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 Pfam PF00654 Voltage gated chloride channel 62 393 1.2E-51 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 PRINTS PR00762 Chloride channel signature 316 336 4.4E-8 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 PRINTS PR00762 Chloride channel signature 344 360 4.4E-8 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS03400 66712587527a403289daebb66b2bd1c9 420 PRINTS PR00762 Chloride channel signature 153 172 4.4E-8 T 23-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 2 310 2.2E-151 T 23-04-2016 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 PANTHER PTHR32332:SF20 1 322 2.9E-132 T 23-04-2016 SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 Gene3D G3DSA:3.20.20.70 1 298 1.7E-74 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 PANTHER PTHR32332 1 322 2.9E-132 T 23-04-2016 SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 Pfam PF03060 Nitronate monooxygenase 3 301 1.7E-72 T 23-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 SPYM18_RS07885 5dfe058c9b21e4151fb1da456ce0a030 323 SUPERFAMILY SSF51412 1 309 9.77E-74 T 23-04-2016 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 SUPERFAMILY SSF51735 1 168 4.71E-18 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 Gene3D G3DSA:1.10.1040.10 185 302 4.5E-41 T 23-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 SUPERFAMILY SSF48179 176 301 5.44E-33 T 23-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 180 301 9.3E-37 T 23-04-2016 IPR013752 Ketopantoate reductase, C-terminal domain GO:0016491|GO:0050661|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 150 3.4E-40 T 23-04-2016 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 PANTHER PTHR21708:SF24 1 303 8.2E-64 T 23-04-2016 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 PANTHER PTHR21708 1 303 8.2E-64 T 23-04-2016 SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 Gene3D G3DSA:3.40.50.720 1 184 3.8E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03925 8c9683451b3019717bb0980547a1281b 307 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 302 5.4E-94 T 23-04-2016 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0015940|GO:0016491|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|UniPathway: UPA00028 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 PANTHER PTHR30193:SF17 123 449 5.3E-78 T 23-04-2016 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 SUPERFAMILY SSF161098 200 439 4.19E-50 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 PANTHER PTHR30193 123 449 5.3E-78 T 23-04-2016 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 235 441 3.6E-21 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 SUPERFAMILY SSF160964 149 200 9.55E-6 T 23-04-2016 SPYM18_RS05710 5eea3da5bfb378a4e39d4c8dab6b433d 453 Gene3D G3DSA:1.10.3720.10 152 439 7.3E-56 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PANTHER PTHR24322 153 185 3.9E-59 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PANTHER PTHR24322 10 137 3.9E-59 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 SUPERFAMILY SSF51735 4 243 1.08E-81 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 9 241 9.4E-97 T 23-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-42 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 Gene3D G3DSA:3.40.50.720 2 243 6.1E-86 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PANTHER PTHR24322:SF328 153 185 3.9E-59 T 23-04-2016 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PANTHER PTHR24322:SF328 10 137 3.9E-59 T 23-04-2016 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 5.8E-61 T 23-04-2016 SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.8E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.8E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.8E-17 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS07875 acf339a6e389b477c494aa3a2c8ae69a 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 1.8E-8 T 23-04-2016 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 SUPERFAMILY SSF46785 3 69 5.95E-15 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 SUPERFAMILY SSF53383 52 363 2.01E-52 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 PANTHER PTHR11751 55 354 7.3E-54 T 23-04-2016 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 Pfam PF00155 Aminotransferase class I and II 76 354 1.3E-14 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 SMART SM00345 8 67 2.6E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 Gene3D G3DSA:3.40.640.10 105 326 6.5E-52 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 67 1.9E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 Gene3D G3DSA:1.10.10.10 2 68 1.0E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05015 1db3183128eab5b6406d580e3e474e89 422 PANTHER PTHR11751:SF294 55 354 7.3E-54 T 23-04-2016 SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 PANTHER PTHR12919 2 83 4.9E-44 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 2.2E-35 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 SUPERFAMILY SSF54565 2 86 1.96E-34 T 23-04-2016 IPR023803 Ribosomal protein S16 domain SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.412 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 Gene3D G3DSA:3.30.1320.10 2 84 1.0E-35 T 23-04-2016 IPR023803 Ribosomal protein S16 domain SPYM18_RS03875 7c24b2ac69304d13177a0a14679f2910 90 Pfam PF00886 Ribosomal protein S16 9 67 9.7E-26 T 23-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS05955 074bb5e56671bf27bdbf75dc9d82eb90 165 SUPERFAMILY SSF55781 4 150 1.57E-37 T 23-04-2016 IPR029016 GAF domain-like SPYM18_RS05955 074bb5e56671bf27bdbf75dc9d82eb90 165 PANTHER PTHR21021:SF15 8 156 3.4E-40 T 23-04-2016 SPYM18_RS05955 074bb5e56671bf27bdbf75dc9d82eb90 165 PANTHER PTHR21021 8 156 3.4E-40 T 23-04-2016 SPYM18_RS05955 074bb5e56671bf27bdbf75dc9d82eb90 165 Gene3D G3DSA:3.30.450.40 3 150 1.2E-41 T 23-04-2016 IPR029016 GAF domain-like SPYM18_RS05955 074bb5e56671bf27bdbf75dc9d82eb90 165 Pfam PF13185 GAF domain 48 149 1.5E-12 T 23-04-2016 IPR003018 GAF domain GO:0005515 SPYM18_RS01860 36aad71b1d36df216fed004cbe621b12 166 SUPERFAMILY SSF109604 15 139 1.88E-19 T 23-04-2016 SPYM18_RS01860 36aad71b1d36df216fed004cbe621b12 166 Gene3D G3DSA:1.10.3210.10 11 142 1.4E-26 T 23-04-2016 IPR006674 HD domain SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 PANTHER PTHR10314 3 306 3.9E-142 T 23-04-2016 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 PANTHER PTHR10314:SF110 3 306 3.9E-142 T 23-04-2016 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 294 8.8E-64 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 305 2.6E-125 T 23-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 305 7.2E-132 T 23-04-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 Gene3D G3DSA:3.40.50.1100 44 144 3.7E-43 T 23-04-2016 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 SUPERFAMILY SSF53686 3 307 3.93E-97 T 23-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 23-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 Gene3D G3DSA:3.40.50.1100 150 306 1.1E-67 T 23-04-2016 SPYM18_RS07030 3807b89bea5f1ac92e6b80878a73b65b 313 Gene3D G3DSA:3.40.50.1100 1 43 1.1E-67 T 23-04-2016 SPYM18_RS09105 5e9c5e71d0d47aec21c0ac1989405728 499 PANTHER PTHR12994:SF17 6 486 2.8E-50 T 23-04-2016 SPYM18_RS09105 5e9c5e71d0d47aec21c0ac1989405728 499 Pfam PF03577 Peptidase family C69 25 428 1.8E-114 T 23-04-2016 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 SPYM18_RS09105 5e9c5e71d0d47aec21c0ac1989405728 499 PANTHER PTHR12994 6 486 2.8E-50 T 23-04-2016 SPYM18_RS09105 5e9c5e71d0d47aec21c0ac1989405728 499 Gene3D G3DSA:3.60.60.10 26 210 1.9E-4 T 23-04-2016 IPR003199 Choloylglycine hydrolase/Peptidase C59 family GO:0016811 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 Pfam PF00425 chorismate binding enzyme 111 365 3.4E-88 T 23-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 Gene3D G3DSA:3.20.10.10 468 566 3.4E-28 T 23-04-2016 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 Pfam PF01063 Amino-transferase class IV 380 569 1.0E-35 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 Gene3D G3DSA:3.30.470.10 380 436 1.5E-4 T 23-04-2016 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 Gene3D G3DSA:3.60.120.10 41 371 2.1E-108 T 23-04-2016 IPR005801 ADC synthase GO:0009058 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PANTHER PTHR11236 40 453 1.1E-146 T 23-04-2016 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 ProSitePatterns PS00770 Aminotransferases class-IV signature. 503 532 - T 23-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PANTHER PTHR11236:SF18 40 453 1.1E-146 T 23-04-2016 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 50 369 2.6E-112 T 23-04-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 SUPERFAMILY SSF56752 321 569 9.68E-36 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PRINTS PR00095 Anthranilate synthase component I signature 322 336 2.2E-7 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PRINTS PR00095 Anthranilate synthase component I signature 213 226 2.2E-7 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PRINTS PR00095 Anthranilate synthase component I signature 307 321 2.2E-7 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 PRINTS PR00095 Anthranilate synthase component I signature 227 240 2.2E-7 T 23-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 SPYM18_RS08855 fed1e5db7cba4a20015995a513d62d03 585 SUPERFAMILY SSF56322 12 371 5.36E-108 T 23-04-2016 IPR005801 ADC synthase GO:0009058 SPYM18_RS04590 5c86435e821caa9015720a355ff91c98 264 PANTHER PTHR30193:SF10 4 264 2.7E-95 T 23-04-2016 SPYM18_RS04590 5c86435e821caa9015720a355ff91c98 264 PANTHER PTHR30193 4 264 2.7E-95 T 23-04-2016 SPYM18_RS04590 5c86435e821caa9015720a355ff91c98 264 SUPERFAMILY SSF161098 2 259 3.36E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04590 5c86435e821caa9015720a355ff91c98 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 56 259 2.4E-6 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS04590 5c86435e821caa9015720a355ff91c98 264 Gene3D G3DSA:1.10.3720.10 8 260 7.4E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 Hamap MF_01491 Ribonuclease J [rnj]. 6 557 45.409 T 23-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 SUPERFAMILY SSF56281 14 425 9.14E-92 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 PIRSF PIRSF004803 3 557 6.3E-222 T 23-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 Gene3D G3DSA:3.60.15.10 8 257 1.9E-78 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 12 554 9.0E-195 T 23-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 Pfam PF00753 Metallo-beta-lactamase superfamily 21 169 2.4E-17 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 366 394 - T 23-04-2016 IPR001587 Ribonuclease J, conserved site SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 PANTHER PTHR11203:SF22 2 557 5.9E-236 T 23-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 SMART SM00849 23 217 7.0E-26 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 360 409 1.9E-10 T 23-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain SPYM18_RS08370 0ee69ea432d7c1f2c902596d8ef837e4 560 PANTHER PTHR11203 2 557 5.9E-236 T 23-04-2016 SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 Gene3D G3DSA:3.40.50.300 2 140 1.1E-4 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 SUPERFAMILY SSF52540 6 210 2.43E-11 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 SUPERFAMILY SSF48019 216 340 4.93E-15 T 23-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 Gene3D G3DSA:1.10.8.60 147 232 1.4E-5 T 23-04-2016 SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 340 8.3E-82 T 23-04-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 Pfam PF06144 DNA polymerase III, delta subunit 20 192 2.3E-51 T 23-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 SPYM18_RS06120 35542479c46456b642e30f18158ecc46 346 PANTHER PTHR34388 1 340 5.7E-46 T 23-04-2016 SPYM18_RS03760 95f844808d380e06bde75290d329e56e 113 PANTHER PTHR41254 2 112 2.0E-28 T 23-04-2016 SPYM18_RS03760 95f844808d380e06bde75290d329e56e 113 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 5 108 1.9E-23 T 23-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPYM18_RS03760 95f844808d380e06bde75290d329e56e 113 Gene3D G3DSA:1.20.1500.10 1 113 1.9E-41 T 23-04-2016 IPR023378 YheA/YmcA-like domain SPYM18_RS03760 95f844808d380e06bde75290d329e56e 113 Hamap MF_01526 UPF0342 protein . 2 113 17.692 T 23-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPYM18_RS03760 95f844808d380e06bde75290d329e56e 113 SUPERFAMILY SSF158622 4 112 1.7E-31 T 23-04-2016 IPR023378 YheA/YmcA-like domain SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 PANTHER PTHR18964:SF114 1 255 1.3E-100 T 23-04-2016 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 SUPERFAMILY SSF51182 1 312 6.02E-103 T 23-04-2016 IPR011051 RmlC-like cupin domain SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 106 312 1.6E-40 T 23-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 Gene3D G3DSA:2.60.120.10 228 313 8.8E-30 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 Pfam PF01238 Phosphomannose isomerase type I 238 312 4.4E-7 T 23-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 Pfam PF01238 Phosphomannose isomerase type I 5 196 1.6E-46 T 23-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 PANTHER PTHR18964 1 255 1.3E-100 T 23-04-2016 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 PIRSF PIRSF036894 2 314 8.4E-126 T 23-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 SPYM18_RS08095 153d6cf8cdb56454262c69dabc66c630 317 Gene3D G3DSA:2.60.120.10 1 216 5.9E-78 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 SUPERFAMILY SSF46785 1 74 1.99E-18 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 234 1.0E-98 T 23-04-2016 IPR012770 Trehalose operon transcriptional repressor SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 SUPERFAMILY SSF64288 54 234 1.43E-33 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 Gene3D G3DSA:1.10.10.10 2 61 2.1E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 Gene3D G3DSA:3.40.1410.10 62 235 2.3E-42 T 23-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PANTHER PTHR11751 1 69 1.2E-21 T 23-04-2016 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PANTHER PTHR11751 117 140 1.2E-21 T 23-04-2016 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 3.3E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 3.3E-8 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 Pfam PF07702 UTRA domain 91 227 2.0E-27 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 66 1.1E-16 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 SMART SM00866 88 227 7.0E-18 T 23-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 SMART SM00345 7 66 1.5E-12 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PANTHER PTHR11751:SF347 1 69 1.2E-21 T 23-04-2016 SPYM18_RS09235 2b9d4dedc49387920fb30caa4efc30a9 237 PANTHER PTHR11751:SF347 117 140 1.2E-21 T 23-04-2016 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 Gene3D G3DSA:3.10.20.120 109 231 2.7E-43 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 ProSitePatterns PS00278 Staphyloccocal enterotoxin/Streptococcal pyrogenic exotoxin signature 2. 149 172 - T 23-04-2016 IPR006126 Staphylococcal enterotoxin/Streptococcal pyrogenic exotoxin, conserved site GO:0005576|GO:0009405 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 PRINTS PR01898 Bacterial superantigen superfamily signature 149 162 4.3E-8 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 PRINTS PR01898 Bacterial superantigen superfamily signature 162 176 4.3E-8 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 PRINTS PR01898 Bacterial superantigen superfamily signature 108 121 4.3E-8 T 23-04-2016 IPR013307 Superantigen, staphylococcal/streptococcal toxin, bacterial SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 Gene3D G3DSA:2.40.50.110 40 108 5.1E-43 T 23-04-2016 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 SUPERFAMILY SSF50203 26 119 6.87E-32 T 23-04-2016 IPR008992 Enterotoxin GO:0009405 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 Pfam PF01123 Staphylococcal/Streptococcal toxin, OB-fold domain 35 117 4.0E-28 T 23-04-2016 IPR006173 Staphylococcal/Streptococcal toxin, OB-fold GO:0009405 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 125 231 3.0E-41 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS08885 162d19056e4cecebda6482252d31c950 233 SUPERFAMILY SSF54334 122 231 4.32E-34 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 SUPERFAMILY SSF51690 137 476 3.53E-127 T 23-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 PIRSF PIRSF000484 2 478 1.7E-149 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 Gene3D G3DSA:3.20.140.10 3 381 1.0E-131 T 23-04-2016 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 PANTHER PTHR11098:SF1 9 478 2.7E-205 T 23-04-2016 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 SUPERFAMILY SSF54675 2 136 8.01E-47 T 23-04-2016 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 PANTHER PTHR11098 9 478 2.7E-205 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 154 334 3.0E-8 T 23-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 SPYM18_RS07175 ad8db23af9ae0162f4fa959d98fdd848 486 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 463 7.7E-188 T 23-04-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 SPYM18_RS02025 72faf64601ed7237094f919937883282 291 SUPERFAMILY SSF52540 8 171 1.16E-30 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02025 72faf64601ed7237094f919937883282 291 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 11 190 4.6E-57 T 23-04-2016 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS02025 72faf64601ed7237094f919937883282 291 PANTHER PTHR11669:SF8 8 160 1.2E-42 T 23-04-2016 SPYM18_RS02025 72faf64601ed7237094f919937883282 291 PANTHER PTHR11669 8 160 1.2E-42 T 23-04-2016 SPYM18_RS02025 72faf64601ed7237094f919937883282 291 Gene3D G3DSA:3.40.50.300 9 161 1.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02025 72faf64601ed7237094f919937883282 291 Pfam PF13177 DNA polymerase III, delta subunit 8 162 8.3E-56 T 23-04-2016 SPYM18_RS02120 d19e1adf7ab1ab94fdfa97d9a728c909 78 Pfam PF11195 Protein of unknown function (DUF2829) 2 76 6.9E-21 T 23-04-2016 IPR021361 Protein of unknown function DUF2829 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 Pfam PF08544 GHMP kinases C terminal 213 301 2.8E-6 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 SUPERFAMILY SSF54211 5 174 2.88E-32 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 Gene3D G3DSA:3.30.70.890 169 299 2.5E-52 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 6 302 1.1E-150 T 23-04-2016 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 98 109 - T 23-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 SUPERFAMILY SSF55060 169 301 1.01E-42 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 Pfam PF00288 GHMP kinases N terminal domain 92 136 7.3E-7 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 PANTHER PTHR10977 5 297 2.6E-88 T 23-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 PIRSF PIRSF015950 1 314 1.8E-104 T 23-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 Gene3D G3DSA:3.30.230.10 5 168 3.1E-62 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS04030 4d87c5f1aeeb5edb20d14a3895f49389 314 PANTHER PTHR10977:SF3 5 297 2.6E-88 T 23-04-2016 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 Gene3D G3DSA:3.40.1370.10 58 207 3.5E-59 T 23-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 1.3E-65 T 23-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.0E-76 T 23-04-2016 IPR013005 50S ribosomal protein uL4 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 36.059 T 23-04-2016 IPR013005 50S ribosomal protein uL4 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 PANTHER PTHR10746 1 206 6.0E-89 T 23-04-2016 IPR013005 50S ribosomal protein uL4 SPYM18_RS00375 864c3953c246053e5a00921756f2e5d2 207 SUPERFAMILY SSF52166 1 206 1.44E-77 T 23-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 SPYM18_RS01695 e1bc3171f70b753e8e286f8ae1971c94 576 Pfam PF03354 Phage Terminase 67 558 5.7E-34 T 23-04-2016 IPR005021 Phage terminase SPYM18_RS01695 e1bc3171f70b753e8e286f8ae1971c94 576 PANTHER PTHR41287 4 576 5.9E-41 T 23-04-2016 SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 SUPERFAMILY SSF52540 4 227 5.11E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 PANTHER PTHR24220:SF239 7 383 2.9E-194 T 23-04-2016 SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 SMART SM00382 30 218 1.8E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 PANTHER PTHR24220 7 383 2.9E-194 T 23-04-2016 SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 Gene3D G3DSA:3.40.50.300 254 492 1.5E-44 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 Gene3D G3DSA:3.40.50.300 2 234 1.1E-63 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 SUPERFAMILY SSF52540 256 486 4.21E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 Pfam PF00005 ABC transporter 275 430 5.5E-17 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05100 964cecc6a5aa64e23604738e3d2063d1 510 Pfam PF00005 ABC transporter 22 170 3.0E-30 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05080 2f9d222c57186364f8cb7691fbf934cf 189 Pfam PF12822 Protein of unknown function (DUF3816) 11 181 2.5E-18 T 23-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 SPYM18_RS07890 a170c972ca34b70e112d36c8b711402f 74 Hamap MF_01217 Acyl carrier protein [acpP]. 2 73 17.988 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 SPYM18_RS07890 a170c972ca34b70e112d36c8b711402f 74 SUPERFAMILY SSF47336 3 72 5.37E-17 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS07890 a170c972ca34b70e112d36c8b711402f 74 Gene3D G3DSA:1.10.1200.10 3 72 3.2E-21 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS07890 a170c972ca34b70e112d36c8b711402f 74 Pfam PF00550 Phosphopantetheine attachment site 5 69 1.3E-14 T 23-04-2016 IPR009081 Phosphopantetheine binding ACP domain SPYM18_RS07890 a170c972ca34b70e112d36c8b711402f 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 72 2.0E-15 T 23-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 SPYM18_RS01520 8b7197410644a7c8bd6e6d7b6be88c69 391 Pfam PF07261 Replication initiation and membrane attachment 268 328 2.8E-5 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS03880 e1a2a90bdbbec562a74338d63e176266 79 SUPERFAMILY SSF54814 11 61 7.85E-5 T 23-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 SPYM18_RS03880 e1a2a90bdbbec562a74338d63e176266 79 Gene3D G3DSA:3.30.300.120 8 77 3.0E-10 T 23-04-2016 SPYM18_RS03880 e1a2a90bdbbec562a74338d63e176266 79 Pfam PF13083 KH domain 6 74 9.0E-16 T 23-04-2016 SPYM18_RS03880 e1a2a90bdbbec562a74338d63e176266 79 Hamap MF_00088 UPF0109 protein . 4 77 15.501 T 23-04-2016 IPR020627 Uncharacterised protein family UPF0109 SPYM18_RS03880 e1a2a90bdbbec562a74338d63e176266 79 PANTHER PTHR34654 2 78 8.3E-22 T 23-04-2016 SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 Pfam PF00483 Nucleotidyl transferase 2 237 1.7E-72 T 23-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 SUPERFAMILY SSF53448 1 286 6.98E-93 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 Gene3D G3DSA:3.90.550.10 1 261 8.0E-70 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 PANTHER PTHR22572:SF105 2 269 3.6E-183 T 23-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 2.3E-153 T 23-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 SPYM18_RS04290 5ba74f5efd55daf70e1ea65a6d9c7156 289 PANTHER PTHR22572 2 269 3.6E-183 T 23-04-2016 SPYM18_RS07805 4ee4164d467206c7ac6f213b86f101ae 473 Pfam PF13250 Domain of unknown function (DUF4041) 193 248 2.8E-16 T 23-04-2016 IPR025280 Domain of unknown function DUF4041 SPYM18_RS07805 4ee4164d467206c7ac6f213b86f101ae 473 SMART SM00974 364 447 4.0E-33 T 23-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding SPYM18_RS07805 4ee4164d467206c7ac6f213b86f101ae 473 Pfam PF10544 T5orf172 domain 354 444 3.3E-15 T 23-04-2016 IPR018306 Bacteriophage T5, Orf172 DNA-binding SPYM18_RS01545 b2c8b20f05a6a9540aa87e24f0b01590 246 SUPERFAMILY SSF50118 60 120 2.62E-7 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS01545 b2c8b20f05a6a9540aa87e24f0b01590 246 Gene3D G3DSA:2.30.30.110 195 237 1.2E-14 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS01545 b2c8b20f05a6a9540aa87e24f0b01590 246 Gene3D G3DSA:2.30.30.110 60 124 1.2E-14 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS01545 b2c8b20f05a6a9540aa87e24f0b01590 246 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 63 129 9.8E-6 T 23-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 PANTHER PTHR30591:SF1 5 1068 2.9E-53 T 23-04-2016 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 TIGRFAM TIGR02774 rexB_recomb: ATP-dependent nuclease subunit B 2 1065 0.0 T 23-04-2016 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 Gene3D G3DSA:3.40.50.300 256 358 9.1E-8 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 Pfam PF12705 PD-(D/E)XK nuclease superfamily 742 1020 5.9E-27 T 23-04-2016 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 PANTHER PTHR30591 5 1068 2.9E-53 T 23-04-2016 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 SUPERFAMILY SSF52980 742 928 2.95E-15 T 23-04-2016 IPR011335 Restriction endonuclease type II-like SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 1 1071 42.467 T 23-04-2016 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 SPYM18_RS03605 1694c6852bda75eca2ce5637d430d760 1071 SUPERFAMILY SSF52540 290 648 5.84E-37 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 6.2E-83 T 23-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:1.10.486.10 387 543 8.6E-43 T 23-04-2016 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:1.10.10.160 112 185 1.8E-26 T 23-04-2016 IPR013986 DExx box DNA helicase domain SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 PANTHER PTHR11070 1 513 2.4E-226 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 PANTHER PTHR11070 532 644 2.4E-226 T 23-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:3.40.50.300 3 107 8.2E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:3.40.50.300 186 284 8.2E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:3.40.50.300 555 644 2.3E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Gene3D G3DSA:3.40.50.300 285 386 2.3E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 PANTHER PTHR11070:SF7 1 513 2.4E-226 T 23-04-2016 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 PANTHER PTHR11070:SF7 532 644 2.4E-226 T 23-04-2016 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 Pfam PF13361 UvrD-like helicase C-terminal domain 276 619 2.9E-76 T 23-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 SUPERFAMILY SSF52540 2 644 4.16E-175 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05270 a9ae3019c6774a25d9fa35f4646d67ba 772 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 770 0.0 T 23-04-2016 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 SPYM18_RS07685 f37e8d917ec597aaaf94bb66223c30f3 124 Pfam PF07852 Protein of unknown function (DUF1642) 3 122 2.5E-21 T 23-04-2016 IPR012865 Protein of unknown function DUF1642 SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 Gene3D G3DSA:3.40.50.300 79 262 3.4E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 PANTHER PTHR30050 91 264 1.7E-17 T 23-04-2016 SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 SUPERFAMILY SSF52540 76 204 3.46E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 Pfam PF01695 IstB-like ATP binding protein 93 263 3.2E-11 T 23-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 PANTHER PTHR30050:SF7 91 264 1.7E-17 T 23-04-2016 SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 SUPERFAMILY SSF52540 116 147 2.66E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07755 5c352f68068e6c8f521789c1d27c50e9 280 SUPERFAMILY SSF52540 198 248 2.66E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 PANTHER PTHR30309:SF0 1 213 6.5E-73 T 23-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 SMART SM01207 8 193 1.6E-74 T 23-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 192 2.8E-49 T 23-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 201 18.839 T 23-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 200 3.0E-51 T 23-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 SPYM18_RS04165 418ebdcbf749b0f2c8d6e65a3001ffe2 213 PANTHER PTHR30309 1 213 6.5E-73 T 23-04-2016 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 186 197 - T 23-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 Pfam PF13484 4Fe-4S double cluster binding domain 186 248 1.1E-12 T 23-04-2016 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 PANTHER PTHR30002:SF4 1 366 7.8E-115 T 23-04-2016 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 SUPERFAMILY SSF46548 159 248 3.82E-12 T 23-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 PANTHER PTHR30002 1 366 7.8E-115 T 23-04-2016 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 Pfam PF08331 Domain of unknown function (DUF1730) 54 133 1.8E-15 T 23-04-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 338 3.1E-112 T 23-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 SPYM18_RS03005 11d76d772fc50352c67ac5a2aa33abf0 374 Gene3D G3DSA:1.25.10.10 296 361 3.7E-5 T 23-04-2016 IPR011989 Armadillo-like helical SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 Gene3D G3DSA:3.40.50.300 3 266 4.3E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 SMART SM00382 37 237 6.4E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 SUPERFAMILY SSF52540 8 258 1.63E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 5.7E-16 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 PANTHER PTHR24220 10 348 1.3E-174 T 23-04-2016 SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 299 1.0E-9 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 PANTHER PTHR24220:SF503 10 348 1.3E-174 T 23-04-2016 SPYM18_RS01355 9e165ebd474df06a58ef8dd19c12b7bb 356 Pfam PF00005 ABC transporter 29 187 3.3E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 TIGRFAM TIGR00861 MIP: MIP family channel proteins 6 229 1.2E-59 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 ProSitePatterns PS00221 MIP family signature. 61 69 - T 23-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 Gene3D G3DSA:1.20.1080.10 2 233 1.9E-84 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PANTHER PTHR19139:SF147 1 235 2.0E-90 T 23-04-2016 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 43 67 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 135 153 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 165 187 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 80 99 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 212 232 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PRINTS PR00783 Major intrinsic protein family signature 1 19 1.3E-49 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 PANTHER PTHR19139 1 235 2.0E-90 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 SUPERFAMILY SSF81338 2 233 7.33E-72 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS02545 77b14cbe4567325c279b93bd5e04455a 236 Pfam PF00230 Major intrinsic protein 2 229 2.7E-47 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS09240 9fb3bd546b4233b03391a570444a75e8 112 Pfam PF01638 HxlR-like helix-turn-helix 16 105 7.4E-36 T 23-04-2016 IPR002577 Helix-turn-helix, HxlR type SPYM18_RS09240 9fb3bd546b4233b03391a570444a75e8 112 Gene3D G3DSA:1.10.10.10 5 104 9.8E-46 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09240 9fb3bd546b4233b03391a570444a75e8 112 PANTHER PTHR33204:SF5 8 104 5.6E-45 T 23-04-2016 SPYM18_RS09240 9fb3bd546b4233b03391a570444a75e8 112 PANTHER PTHR33204 8 104 5.6E-45 T 23-04-2016 SPYM18_RS09240 9fb3bd546b4233b03391a570444a75e8 112 SUPERFAMILY SSF46785 5 106 8.56E-36 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06040 961b2f7137ec9e16081882645d7537a7 256 Pfam PF11368 Protein of unknown function (DUF3169) 5 250 4.7E-48 T 23-04-2016 IPR021509 Protein of unknown function DUF3169 SPYM18_RS00995 f7513397dec0ef5547ec9b08d42989d7 151 Pfam PF13380 CoA binding domain 21 137 3.4E-31 T 23-04-2016 IPR003781 CoA-binding GO:0048037 SPYM18_RS00995 f7513397dec0ef5547ec9b08d42989d7 151 SUPERFAMILY SSF51735 13 139 1.33E-34 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00995 f7513397dec0ef5547ec9b08d42989d7 151 SMART SM00881 17 111 6.9E-15 T 23-04-2016 IPR003781 CoA-binding GO:0048037 SPYM18_RS00995 f7513397dec0ef5547ec9b08d42989d7 151 Gene3D G3DSA:3.40.50.720 12 140 1.2E-40 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00995 f7513397dec0ef5547ec9b08d42989d7 151 PANTHER PTHR33303 1 142 5.0E-41 T 23-04-2016 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 Pfam PF00296 Luciferase-like monooxygenase 11 300 3.8E-28 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 SUPERFAMILY SSF51679 1 327 1.57E-62 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 PANTHER PTHR30137 1 328 5.5E-84 T 23-04-2016 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 327 6.3E-104 T 23-04-2016 IPR019949 Luciferase family oxidoreductase, group 1 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 Gene3D G3DSA:3.20.20.30 1 327 3.0E-70 T 23-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 SPYM18_RS05055 e2f8c11c843eba633668edb7541a46d3 332 PANTHER PTHR30137:SF2 1 328 5.5E-84 T 23-04-2016 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 PANTHER PTHR11002 1 165 4.2E-56 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 Pfam PF00484 Carbonic anhydrase 32 159 9.0E-14 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 SUPERFAMILY SSF53056 4 163 1.83E-40 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 SMART SM00947 24 164 8.1E-28 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 PANTHER PTHR11002:SF9 1 165 4.2E-56 T 23-04-2016 SPYM18_RS01105 a6c833bb1d3fcf505bfdc12eae065899 165 Gene3D G3DSA:3.40.1050.10 3 163 5.5E-41 T 23-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 SPYM18_RS05370 39b31404cf4b02c2960a7039fe456e65 288 Pfam PF03904 Domain of unknown function (DUF334) 60 194 9.1E-6 T 23-04-2016 IPR005602 Protein of unknown function DUF334 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 PANTHER PTHR21234:SF8 5 258 3.7E-57 T 23-04-2016 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 Pfam PF01048 Phosphorylase superfamily 23 236 1.0E-42 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 69 84 - T 23-04-2016 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 SUPERFAMILY SSF53167 10 255 1.7E-75 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 11 253 5.2E-98 T 23-04-2016 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|UniPathway: UPA00574 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 Gene3D G3DSA:3.40.50.1580 17 250 4.1E-81 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS08335 ad01dbec623041a8cc5bd2b426c4021a 259 PANTHER PTHR21234 5 258 3.7E-57 T 23-04-2016 IPR018017 Nucleoside phosphorylase SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 Gene3D G3DSA:3.30.460.20 17 116 1.7E-4 T 23-04-2016 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 Gene3D G3DSA:1.20.58.340 236 314 7.7E-18 T 23-04-2016 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 SUPERFAMILY SSF144083 247 312 1.05E-11 T 23-04-2016 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 PANTHER PTHR21535 4 314 6.1E-85 T 23-04-2016 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 PANTHER PTHR21535:SF40 4 314 6.1E-85 T 23-04-2016 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 Pfam PF01544 CorA-like Mg2+ transporter protein 22 310 1.8E-62 T 23-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 SPYM18_RS08155 51da040b9ddccbfc8eb9599481725b79 314 SUPERFAMILY SSF143865 19 246 2.75E-44 T 23-04-2016 SPYM18_RS03685 03e4833bb9b909cfaa758fc858fa3ea0 231 Pfam PF00535 Glycosyl transferase family 2 5 163 5.4E-25 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS03685 03e4833bb9b909cfaa758fc858fa3ea0 231 PANTHER PTHR10859 4 222 2.6E-51 T 23-04-2016 SPYM18_RS03685 03e4833bb9b909cfaa758fc858fa3ea0 231 PANTHER PTHR10859:SF84 4 222 2.6E-51 T 23-04-2016 SPYM18_RS03685 03e4833bb9b909cfaa758fc858fa3ea0 231 SUPERFAMILY SSF53448 5 217 1.3E-39 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03685 03e4833bb9b909cfaa758fc858fa3ea0 231 Gene3D G3DSA:3.90.550.10 5 166 3.1E-21 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 PIRSF PIRSF005572 1 380 8.7E-112 T 23-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 Pfam PF00266 Aminotransferase class-V 2 365 2.8E-65 T 23-04-2016 IPR000192 Aminotransferase class V domain SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 PANTHER PTHR11601 1 380 1.9E-189 T 23-04-2016 SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 PANTHER PTHR11601:SF50 1 380 1.9E-189 T 23-04-2016 SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 Gene3D G3DSA:3.90.1150.10 248 372 5.0E-30 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 23-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 SUPERFAMILY SSF53383 1 374 1.81E-89 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS03780 d4393daab71c27e97f5cd93f74c74ef1 380 Gene3D G3DSA:3.40.640.10 16 247 3.6E-75 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 SUPERFAMILY SSF51569 1 303 8.06E-87 T 23-04-2016 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 Gene3D G3DSA:3.20.20.70 1 278 1.6E-113 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 PANTHER PTHR18866 1 453 5.3E-167 T 23-04-2016 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 PANTHER PTHR18866:SF109 1 453 5.3E-167 T 23-04-2016 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 Pfam PF02436 Conserved carboxylase domain 295 453 4.8E-48 T 23-04-2016 IPR003379 Carboxylase, conserved domain SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 Pfam PF00682 HMGL-like 4 269 3.6E-48 T 23-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 SPYM18_RS04870 d98427f488594f22b6c684957f893a38 460 SUPERFAMILY SSF89000 300 451 8.24E-45 T 23-04-2016 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PANTHER PTHR19139:SF147 9 168 4.2E-61 T 23-04-2016 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PANTHER PTHR19139:SF147 189 279 4.2E-61 T 23-04-2016 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 ProSitePatterns PS00221 MIP family signature. 67 75 - T 23-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PANTHER PTHR19139 9 168 4.2E-61 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PANTHER PTHR19139 189 279 4.2E-61 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 Gene3D G3DSA:1.20.1080.10 3 280 4.6E-80 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 49 73 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 86 105 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 208 230 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 150 168 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 259 279 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 PRINTS PR00783 Major intrinsic protein family signature 7 26 4.6E-40 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 SUPERFAMILY SSF81338 5 169 3.14E-61 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 SUPERFAMILY SSF81338 202 280 3.14E-61 T 23-04-2016 IPR023271 Aquaporin-like SPYM18_RS08265 1a58c995084dfd7f73d403fe92e80797 282 Pfam PF00230 Major intrinsic protein 8 273 1.4E-38 T 23-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 SPYM18_RS05050 3c953b554aa778bf4e815fd25c896331 110 Gene3D G3DSA:2.40.50.100 10 109 1.5E-18 T 23-04-2016 SPYM18_RS05050 3c953b554aa778bf4e815fd25c896331 110 Pfam PF01597 Glycine cleavage H-protein 11 105 1.3E-12 T 23-04-2016 IPR002930 Glycine cleavage system H-protein SPYM18_RS05050 3c953b554aa778bf4e815fd25c896331 110 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 40 69 - T 23-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site SPYM18_RS05050 3c953b554aa778bf4e815fd25c896331 110 SUPERFAMILY SSF51230 3 109 7.98E-21 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS06470 d19c9d3aea12df1dc3b972c2a3dc928b 70 Gene3D G3DSA:1.10.260.40 4 61 2.6E-19 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS06470 d19c9d3aea12df1dc3b972c2a3dc928b 70 Pfam PF01381 Helix-turn-helix 4 59 3.8E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06470 d19c9d3aea12df1dc3b972c2a3dc928b 70 SMART SM00530 3 59 1.2E-13 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06470 d19c9d3aea12df1dc3b972c2a3dc928b 70 SUPERFAMILY SSF47413 10 64 9.85E-15 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 SUPERFAMILY SSF56796 1 356 3.93E-89 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 Gene3D G3DSA:1.20.1090.10 159 360 5.5E-67 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 PANTHER PTHR11496:SF57 1 361 3.1E-173 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 PIRSF PIRSF000112 1 361 7.8E-103 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 Gene3D G3DSA:3.40.50.1970 1 157 3.6E-42 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 PANTHER PTHR11496 1 361 3.1E-173 T 23-04-2016 SPYM18_RS09030 917683ac481cb3ad2542fec2cbde1282 362 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 348 7.1E-65 T 23-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 SPYM18_RS03320 6253f7cc7e64ce4a7aab7a550d47eca0 142 Pfam PF07761 Protein of unknown function (DUF1617) 1 140 3.8E-89 T 23-04-2016 IPR011675 Protein of unknown function DUF1617 SPYM18_RS04485 2c626408076d483225af46ec3feff958 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 456 509 4.6E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04485 2c626408076d483225af46ec3feff958 549 PANTHER PTHR34220 196 529 4.9E-33 T 23-04-2016 SPYM18_RS04485 2c626408076d483225af46ec3feff958 549 SUPERFAMILY SSF55874 417 531 1.96E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04485 2c626408076d483225af46ec3feff958 549 Gene3D G3DSA:3.30.565.10 405 528 1.2E-13 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04485 2c626408076d483225af46ec3feff958 549 Pfam PF06580 Histidine kinase 358 432 3.7E-19 T 23-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 Gene3D G3DSA:3.30.9.10 199 302 1.4E-16 T 23-04-2016 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 SUPERFAMILY SSF54373 212 302 2.62E-12 T 23-04-2016 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 PANTHER PTHR13847:SF211 5 363 1.1E-106 T 23-04-2016 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 Pfam PF01266 FAD dependent oxidoreductase 2 342 6.1E-43 T 23-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 SUPERFAMILY SSF51905 303 361 1.55E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 SUPERFAMILY SSF51905 1 212 1.55E-28 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 Gene3D G3DSA:3.50.50.60 1 79 9.6E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 Gene3D G3DSA:3.50.50.60 303 358 9.6E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 Gene3D G3DSA:3.50.50.60 140 198 9.6E-33 T 23-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 SPYM18_RS04285 0f8fd04f60a89c66c7c33adc8cb45b38 368 PANTHER PTHR13847 5 363 1.1E-106 T 23-04-2016 SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 Pfam PF01926 50S ribosome-binding GTPase 166 229 3.0E-13 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 PANTHER PTHR11089 1 372 1.7E-203 T 23-04-2016 SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 SUPERFAMILY SSF52540 64 266 1.57E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 372 1.2E-152 T 23-04-2016 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 PANTHER PTHR11089:SF34 1 372 1.7E-203 T 23-04-2016 SPYM18_RS01405 2bac35426c05c876c984d6d82f8712a7 372 Gene3D G3DSA:3.40.50.300 74 225 3.7E-28 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01705 a8af3a75363bd53aeacec1093a3ca411 395 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 30 367 5.2E-93 T 23-04-2016 IPR006427 Phage portal protein, HK97 SPYM18_RS01705 a8af3a75363bd53aeacec1093a3ca411 395 Pfam PF04860 Phage portal protein 37 359 4.9E-22 T 23-04-2016 IPR006944 Bacteriophage/Gene transfer agent portal protein SPYM18_RS07390 66a663fcba7c5e8666e195795d5d360a 157 Gene3D G3DSA:3.40.930.10 7 145 1.9E-25 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS07390 66a663fcba7c5e8666e195795d5d360a 157 SUPERFAMILY SSF55804 6 144 6.02E-22 T 23-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 SPYM18_RS07390 66a663fcba7c5e8666e195795d5d360a 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 8 147 2.8E-17 T 23-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Gene3D G3DSA:4.10.320.10 175 221 1.1E-17 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Gene3D G3DSA:4.10.320.10 129 174 1.9E-20 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Gene3D G3DSA:2.40.50.100 1 93 1.3E-28 T 23-04-2016 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Gene3D G3DSA:3.30.559.10 233 468 6.8E-76 T 23-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Pfam PF00364 Biotin-requiring enzyme 4 76 3.9E-20 T 23-04-2016 IPR000089 Biotin/lipoyl attachment SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 SUPERFAMILY SSF47005 127 171 1.57E-13 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 23-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 SUPERFAMILY SSF47005 173 214 8.11E-11 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 SUPERFAMILY SSF52777 234 469 7.56E-74 T 23-04-2016 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Pfam PF02817 e3 binding domain 175 209 2.7E-13 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Pfam PF02817 e3 binding domain 133 168 1.8E-15 T 23-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 PANTHER PTHR23151 218 468 1.7E-141 T 23-04-2016 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 PANTHER PTHR23151 4 176 1.7E-141 T 23-04-2016 SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 SUPERFAMILY SSF51230 1 89 3.26E-26 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS04370 2690b5d9e81a02b9bde027820a7ec1dc 469 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 238 468 1.0E-73 T 23-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 SPYM18_RS09015 1061bfb059aa1bc4c97959300b63911b 280 SUPERFAMILY SSF47413 1 63 9.6E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09015 1061bfb059aa1bc4c97959300b63911b 280 PANTHER PTHR37038 1 275 7.5E-20 T 23-04-2016 SPYM18_RS09015 1061bfb059aa1bc4c97959300b63911b 280 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 62 278 1.8E-63 T 23-04-2016 IPR010057 Transcription activator MutR, C-terminal SPYM18_RS09015 1061bfb059aa1bc4c97959300b63911b 280 Gene3D G3DSA:1.10.260.40 3 75 3.3E-4 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00855 7553286f4165a87dcdc8b5417e03ad4a 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 8 97 2.0E-19 T 23-04-2016 IPR008218 ATPase, V1 complex, subunit F GO:0034220 SPYM18_RS00855 7553286f4165a87dcdc8b5417e03ad4a 106 SUPERFAMILY SSF159468 8 105 9.94E-22 T 23-04-2016 IPR008218 ATPase, V1 complex, subunit F GO:0034220 SPYM18_RS00855 7553286f4165a87dcdc8b5417e03ad4a 106 Gene3D G3DSA:3.40.50.10580 7 105 1.5E-19 T 23-04-2016 IPR008218 ATPase, V1 complex, subunit F GO:0034220 SPYM18_RS03450 e9a1b8c3a2ece3af4b4d797119e7da3e 316 Pfam PF00881 Nitroreductase family 125 311 7.8E-31 T 23-04-2016 IPR029479 Nitroreductase SPYM18_RS03450 e9a1b8c3a2ece3af4b4d797119e7da3e 316 SUPERFAMILY SSF55469 123 312 6.0E-21 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS03450 e9a1b8c3a2ece3af4b4d797119e7da3e 316 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 141 312 4.9E-57 T 23-04-2016 IPR020051 SagB-type dehydrogenase domain SPYM18_RS03450 e9a1b8c3a2ece3af4b4d797119e7da3e 316 Gene3D G3DSA:3.40.109.10 121 313 1.6E-16 T 23-04-2016 IPR000415 Nitroreductase-like GO:0016491 SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 SUPERFAMILY SSF46785 140 218 3.4E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 SUPERFAMILY SSF51206 7 136 1.79E-17 T 23-04-2016 IPR018490 Cyclic nucleotide-binding-like SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 Gene3D G3DSA:1.10.10.10 136 217 5.7E-27 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 ProSitePatterns PS00042 Crp-type HTH domain signature. 168 192 - T 23-04-2016 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 SMART SM00419 160 209 6.8E-8 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08280 79113ce6fc57ea61e11f40e604d2e3e7 219 Pfam PF13545 Crp-like helix-turn-helix domain 160 215 2.5E-11 T 23-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 SPYM18_RS03830 c592642d5c1983cf66c06e7f7b0d059f 173 SUPERFAMILY SSF53271 5 167 2.36E-36 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS03830 c592642d5c1983cf66c06e7f7b0d059f 173 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 171 35.438 T 23-04-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 SPYM18_RS03830 c592642d5c1983cf66c06e7f7b0d059f 173 Gene3D G3DSA:3.40.50.2020 3 166 5.0E-45 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS03830 c592642d5c1983cf66c06e7f7b0d059f 173 PANTHER PTHR11608 1 173 2.5E-81 T 23-04-2016 SPYM18_RS03830 c592642d5c1983cf66c06e7f7b0d059f 173 Pfam PF00156 Phosphoribosyl transferase domain 4 154 3.1E-21 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 PANTHER PTHR30246 1 211 6.6E-82 T 23-04-2016 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 PANTHER PTHR30246:SF4 1 211 6.6E-82 T 23-04-2016 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 SUPERFAMILY SSF51569 3 208 1.45E-56 T 23-04-2016 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 8 204 1.5E-49 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 Pfam PF01081 KDPG and KHG aldolase 8 187 2.0E-40 T 23-04-2016 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 SPYM18_RS02995 9e1590a4a500b7545f6d8232b2fe4ae8 211 Gene3D G3DSA:3.20.20.70 3 210 1.2E-69 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 SUPERFAMILY SSF53756 9 329 2.33E-44 T 23-04-2016 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 Gene3D G3DSA:3.40.50.2000 127 265 1.1E-12 T 23-04-2016 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 Pfam PF00534 Glycosyl transferases group 1 156 268 5.6E-9 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 PANTHER PTHR12526 44 331 2.0E-28 T 23-04-2016 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 PANTHER PTHR12526:SF394 44 331 2.0E-28 T 23-04-2016 SPYM18_RS02485 f9d66a20630f4e993a7193e8cdf98270 332 Pfam PF13439 Glycosyltransferase Family 4 43 140 6.2E-15 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 225 4.0E-58 T 23-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 23-04-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 SMART SM00934 5 224 2.1E-90 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 224 2.7E-48 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 Gene3D G3DSA:3.20.20.70 2 229 1.3E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 PANTHER PTHR32119 1 228 9.4E-102 T 23-04-2016 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 229 39.386 T 23-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 PANTHER PTHR32119:SF2 1 228 9.4E-102 T 23-04-2016 SPYM18_RS04130 ae8a1205eb0483b17d35d9c84352a9c0 230 SUPERFAMILY SSF51366 1 228 1.06E-69 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPYM18_RS03360 e1b85e2412289634289b046294e2c9d4 472 Pfam PF03577 Peptidase family C69 9 409 2.4E-201 T 23-04-2016 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 SPYM18_RS03360 e1b85e2412289634289b046294e2c9d4 472 PANTHER PTHR12994 10 465 6.8E-59 T 23-04-2016 SPYM18_RS03360 e1b85e2412289634289b046294e2c9d4 472 PANTHER PTHR12994:SF17 10 465 6.8E-59 T 23-04-2016 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 201 1.2E-83 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 Gene3D G3DSA:4.10.960.10 82 154 4.2E-32 T 23-04-2016 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 Gene3D G3DSA:2.40.30.10 4 33 2.5E-15 T 23-04-2016 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 Gene3D G3DSA:2.40.30.10 155 206 2.5E-15 T 23-04-2016 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 23-04-2016 IPR019926 Ribosomal protein L3, conserved site SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 SUPERFAMILY SSF50447 1 205 2.12E-79 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 204 38.457 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 Pfam PF00297 Ribosomal protein L3 98 177 9.8E-15 T 23-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00370 caa12f938a461bd1a59ac39df002b888 208 PANTHER PTHR11229 1 208 3.5E-110 T 23-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 SUPERFAMILY SSF54184 694 750 5.36E-11 T 23-04-2016 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 PANTHER PTHR30627:SF1 10 620 1.3E-140 T 23-04-2016 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 SMART SM00740 690 751 1.5E-13 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 Pfam PF03717 Penicillin-binding Protein dimerisation domain 73 246 4.3E-27 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 Pfam PF00905 Penicillin binding protein transpeptidase domain 292 599 2.0E-71 T 23-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 Pfam PF03793 PASTA domain 694 750 7.1E-8 T 23-04-2016 IPR005543 PASTA domain SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 PANTHER PTHR30627 10 620 1.3E-140 T 23-04-2016 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 SUPERFAMILY SSF54184 633 691 7.85E-16 T 23-04-2016 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 Gene3D G3DSA:3.40.710.10 273 611 3.4E-69 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 SUPERFAMILY SSF56601 266 626 1.57E-71 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 SUPERFAMILY SSF56519 70 265 1.15E-47 T 23-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 SPYM18_RS07215 660cd3c3f5e0c5222278671b5aa27b35 751 Gene3D G3DSA:3.90.1310.10 167 272 7.8E-31 T 23-04-2016 SPYM18_RS05420 e97f17eb3191c6dda7ecd5eadb1d5a7e 332 SUPERFAMILY SSF69349 7 330 8.63E-130 T 23-04-2016 SPYM18_RS05420 e97f17eb3191c6dda7ecd5eadb1d5a7e 332 Pfam PF07212 Hyaluronidase protein (HylP) 56 332 4.8E-154 T 23-04-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 PANTHER PTHR11601:SF20 1 369 5.9E-143 T 23-04-2016 SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 191 210 - T 23-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 Pfam PF00266 Aminotransferase class-V 3 361 1.2E-74 T 23-04-2016 IPR000192 Aminotransferase class V domain SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 Gene3D G3DSA:3.90.1150.10 243 368 2.1E-29 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 SUPERFAMILY SSF53383 1 369 1.84E-101 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 PIRSF PIRSF005572 1 373 9.1E-112 T 23-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 PANTHER PTHR11601 1 369 5.9E-143 T 23-04-2016 SPYM18_RS04670 d412450f4aa1dd3f4e1207320333a4e3 375 Gene3D G3DSA:3.40.640.10 14 242 1.3E-83 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 PANTHER PTHR35039 1 220 2.0E-103 T 23-04-2016 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 SUPERFAMILY SSF51366 4 215 5.3E-37 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 PANTHER PTHR35039:SF2 1 220 2.0E-103 T 23-04-2016 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 SMART SM00934 6 211 1.1E-27 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 Gene3D G3DSA:3.20.20.70 4 219 2.7E-74 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS00955 0bbf86c94bf0dee36577ec7eb11359c5 220 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 5 210 1.8E-30 T 23-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 461 5.0E-195 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SMART SM00116 100 150 8.2E-8 T 23-04-2016 IPR000644 CBS domain SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SMART SM00116 163 211 5.7E-8 T 23-04-2016 IPR000644 CBS domain SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 23-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 PANTHER PTHR11911:SF6 1 287 1.0E-245 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 PANTHER PTHR11911:SF6 305 491 1.0E-245 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SUPERFAMILY SSF54631 99 210 1.21E-28 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SMART SM01240 11 479 0.0 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 PIRSF PIRSF000130 3 493 1.8E-210 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 Gene3D G3DSA:3.20.20.70 9 491 3.1E-203 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 PANTHER PTHR11911 1 287 1.0E-245 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 PANTHER PTHR11911 305 491 1.0E-245 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 6.1E-159 T 23-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 Pfam PF00571 CBS domain 161 206 3.7E-6 T 23-04-2016 IPR000644 CBS domain SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 Pfam PF00571 CBS domain 100 146 7.9E-7 T 23-04-2016 IPR000644 CBS domain SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SUPERFAMILY SSF51412 7 94 1.05E-123 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 SUPERFAMILY SSF51412 222 483 1.05E-123 T 23-04-2016 SPYM18_RS09590 01d1a7a4fcae807ea5400c8aa7781d23 493 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 84.257 T 23-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PANTHER PTHR11533:SF163 7 842 8.4E-232 T 23-04-2016 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PANTHER PTHR11533 7 842 8.4E-232 T 23-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 289 304 2.6E-30 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 308 320 2.6E-30 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 175 190 2.6E-30 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 126 141 2.6E-30 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 254 264 2.6E-30 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 Gene3D G3DSA:1.10.390.10 302 449 2.6E-46 T 23-04-2016 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 Pfam PF01433 Peptidase family M1 7 382 1.9E-127 T 23-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 SUPERFAMILY SSF55486 201 449 2.78E-76 T 23-04-2016 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 SUPERFAMILY SSF63737 9 192 1.27E-47 T 23-04-2016 SPYM18_RS05140 fa303da44e56012a73ac9b2d682ebb5c 845 Pfam PF11838 ERAP1-like C-terminal domain 512 825 3.2E-33 T 23-04-2016 IPR024571 ERAP1-like C-terminal domain SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 Pfam PF01261 Xylose isomerase-like TIM barrel 22 233 3.5E-37 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 PANTHER PTHR12110:SF20 4 286 6.3E-105 T 23-04-2016 SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 PANTHER PTHR12110 4 286 6.3E-105 T 23-04-2016 SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 Gene3D G3DSA:3.20.20.150 6 271 3.6E-48 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 SUPERFAMILY SSF51658 11 283 3.8E-58 T 23-04-2016 IPR013022 Xylose isomerase-like, TIM barrel domain SPYM18_RS00960 ed2b8fdc43e123137e2db4390baa6936 287 TIGRFAM TIGR00542 hxl6Piso_put: putative hexulose-6-phosphate isomerase 4 286 8.8E-113 T 23-04-2016 IPR004560 L-ribulose-5-phosphate 3-epimerase GO:0005975|GO:0016861 KEGG: 00053+5.1.3.22|MetaCyc: PWY-6961|UniPathway: UPA00263 SPYM18_RS02820 17ce2245c305d4ffe59eb5615257dda1 308 PANTHER PTHR30217 1 307 1.3E-143 T 23-04-2016 SPYM18_RS02820 17ce2245c305d4ffe59eb5615257dda1 308 PANTHER PTHR30217:SF7 1 307 1.3E-143 T 23-04-2016 SPYM18_RS02820 17ce2245c305d4ffe59eb5615257dda1 308 Pfam PF01136 Peptidase family U32 74 303 2.5E-37 T 23-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 Pfam PF05649 Peptidase family M13 5 384 2.0E-62 T 23-04-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 SUPERFAMILY SSF55486 5 631 3.52E-191 T 23-04-2016 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 Gene3D G3DSA:3.40.390.10 429 631 7.5E-91 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 Gene3D G3DSA:3.40.390.10 272 387 7.5E-91 T 23-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 469 485 7.4E-21 T 23-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 430 442 7.4E-21 T 23-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 539 550 7.4E-21 T 23-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 448 460 7.4E-21 T 23-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PANTHER PTHR11733:SF65 6 631 1.4E-143 T 23-04-2016 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 PANTHER PTHR11733 6 631 1.4E-143 T 23-04-2016 IPR000718 Peptidase M13 GO:0004222|GO:0006508 SPYM18_RS09220 35e7cb1a1cfaf4ffbbeb7065207816e0 631 Pfam PF01431 Peptidase family M13 438 628 8.7E-63 T 23-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 SMART SM00529 23 122 1.4E-33 T 23-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 Pfam PF04023 FeoA domain 142 213 7.2E-6 T 23-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 SUPERFAMILY SSF46785 1 61 3.91E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 PANTHER PTHR33238:SF1 1 213 5.5E-69 T 23-04-2016 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 130 1.2E-25 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 SUPERFAMILY SSF47979 63 135 1.44E-24 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 SMART SM00899 142 214 0.0014 T 23-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 Gene3D G3DSA:1.10.60.10 72 133 1.1E-28 T 23-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 Gene3D G3DSA:1.10.10.10 1 69 8.8E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 PANTHER PTHR33238 1 213 5.5E-69 T 23-04-2016 SPYM18_RS02165 039585334f2c9256b692953b50d57c13 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 58 4.7E-15 T 23-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 PANTHER PTHR24220 5 227 8.8E-92 T 23-04-2016 SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 SMART SM00382 30 218 7.3E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 PANTHER PTHR24220:SF594 5 227 8.8E-92 T 23-04-2016 SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 Pfam PF00005 ABC transporter 21 169 8.0E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 Gene3D G3DSA:3.40.50.300 4 227 1.5E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08550 9803c22ae01837bba1bc9f5895f93efa 245 SUPERFAMILY SSF52540 5 223 3.84E-61 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 SUPERFAMILY SSF160240 212 288 1.44E-17 T 23-04-2016 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 Gene3D G3DSA:3.30.70.1350 210 289 2.2E-23 T 23-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 PANTHER PTHR11562:SF18 17 299 1.8E-61 T 23-04-2016 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 Pfam PF16916 Dimerisation domain of Zinc Transporter 216 289 2.4E-16 T 23-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 Pfam PF01545 Cation efflux family 17 208 8.7E-45 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 PANTHER PTHR11562 17 299 1.8E-61 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 SUPERFAMILY SSF161111 9 210 3.66E-47 T 23-04-2016 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 14 289 9.9E-56 T 23-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 SPYM18_RS05280 ffe6796ca2a95f2305b7e3b91e0bd908 411 Gene3D G3DSA:1.20.1510.10 17 208 4.7E-41 T 23-04-2016 IPR027469 Cation efflux protein transmembrane domain SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 SUPERFAMILY SSF52833 4 134 7.88E-37 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 Pfam PF03960 ArsC family 7 114 1.2E-16 T 23-04-2016 IPR006660 Arsenate reductase-like SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 4 116 2.2E-36 T 23-04-2016 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 Gene3D G3DSA:3.40.30.10 1 132 9.6E-52 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 PANTHER PTHR30041 1 136 6.2E-40 T 23-04-2016 SPYM18_RS04100 6a404c1d2feec1a0fdc5f59021fe53ec 146 PANTHER PTHR30041:SF0 1 136 6.2E-40 T 23-04-2016 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 Pfam PF01791 DeoC/LacD family aldolase 23 195 3.5E-16 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 Gene3D G3DSA:3.20.20.70 3 215 3.3E-80 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 PANTHER PTHR10889 2 214 1.4E-79 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 4 217 32.927 T 23-04-2016 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 PIRSF PIRSF001357 1 222 9.1E-78 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 SMART SM01133 5 215 7.9E-79 T 23-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 SUPERFAMILY SSF51569 4 215 8.16E-73 T 23-04-2016 SPYM18_RS08325 89537647db393a42695dcf32e469c12f 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 6 213 1.1E-67 T 23-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 SPYM18_RS07670 cc0e43dc6d399083244a8f5d2370d282 172 Pfam PF02195 ParB-like nuclease domain 7 88 2.0E-16 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS07670 cc0e43dc6d399083244a8f5d2370d282 172 SUPERFAMILY SSF110849 7 158 8.76E-43 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS07670 cc0e43dc6d399083244a8f5d2370d282 172 Gene3D G3DSA:3.90.1530.10 6 88 6.9E-22 T 23-04-2016 SPYM18_RS07670 cc0e43dc6d399083244a8f5d2370d282 172 PANTHER PTHR33375 8 88 1.2E-14 T 23-04-2016 SPYM18_RS07670 cc0e43dc6d399083244a8f5d2370d282 172 SMART SM00470 4 89 1.3E-20 T 23-04-2016 IPR003115 ParB/Sulfiredoxin SPYM18_RS05860 10df71c1ca9fc42ebe26aca7e758d5f1 121 Gene3D G3DSA:3.10.129.10 5 121 6.5E-40 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS05860 10df71c1ca9fc42ebe26aca7e758d5f1 121 PANTHER PTHR36934 13 121 2.8E-20 T 23-04-2016 SPYM18_RS05860 10df71c1ca9fc42ebe26aca7e758d5f1 121 Pfam PF03061 Thioesterase superfamily 26 98 4.5E-5 T 23-04-2016 IPR006683 Thioesterase domain SPYM18_RS05860 10df71c1ca9fc42ebe26aca7e758d5f1 121 PIRSF PIRSF014972 2 121 1.9E-29 T 23-04-2016 IPR025540 Fluoroacetyl-CoA thioesterase SPYM18_RS05860 10df71c1ca9fc42ebe26aca7e758d5f1 121 SUPERFAMILY SSF54637 4 120 8.46E-34 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 23-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 SUPERFAMILY SSF100950 80 236 4.61E-28 T 23-04-2016 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 PANTHER PTHR30363:SF10 1 254 3.0E-95 T 23-04-2016 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 SMART SM00420 6 58 2.3E-22 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 Gene3D G3DSA:1.10.10.10 4 59 5.8E-10 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 SMART SM01134 78 237 1.5E-58 T 23-04-2016 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 1.6E-19 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 PANTHER PTHR30363 1 254 3.0E-95 T 23-04-2016 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 Gene3D G3DSA:3.40.50.1360 80 217 2.2E-9 T 23-04-2016 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 Pfam PF00455 DeoR C terminal sensor domain 80 236 1.5E-45 T 23-04-2016 IPR014036 DeoR C-terminal sensor domain SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 SUPERFAMILY SSF46785 4 62 1.25E-14 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.8E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS08600 185cf6520b9e364450d812758de6a9db 257 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.8E-10 T 23-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 PANTHER PTHR22993 1 273 4.2E-110 T 23-04-2016 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 271 1.2E-102 T 23-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Pfam PF06827 Zinc finger found in FPG and IleRS 244 272 2.6E-11 T 23-04-2016 IPR010663 Zinc finger, FPG/IleRS-type SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Gene3D G3DSA:3.20.190.10 2 129 1.7E-36 T 23-04-2016 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 132 222 3.5E-31 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 SUPERFAMILY SSF81624 2 141 1.44E-38 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 SMART SM01232 132 224 4.0E-40 T 23-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 9.5E-33 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 SUPERFAMILY SSF46946 131 220 4.71E-28 T 23-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 SMART SM00898 2 116 3.4E-47 T 23-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 PANTHER PTHR22993:SF15 1 273 4.2E-110 T 23-04-2016 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 272 42.98 T 23-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 Gene3D G3DSA:1.10.8.50 132 272 2.5E-48 T 23-04-2016 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 SUPERFAMILY SSF57716 221 272 1.34E-16 T 23-04-2016 SPYM18_RS02400 390acf0b7c907d9cd0a91d6b343964cf 275 ProSitePatterns PS01242 Zinc finger FPG-type signature. 247 271 - T 23-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 SPYM18_RS02830 d84d2d6fc771bc08a4f03a4f9659d41d 70 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 19 66 7.0E-10 T 23-04-2016 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 SPYM18_RS02830 d84d2d6fc771bc08a4f03a4f9659d41d 70 PIRSF PIRSF037246 1 70 3.8E-35 T 23-04-2016 IPR017154 Uncharacterised conserved protein UCP037246 SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 316 1.5E-75 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 SUPERFAMILY SSF51735 1 337 1.37E-94 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 PANTHER PTHR10366 4 343 7.2E-194 T 23-04-2016 SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 328 3.0E-135 T 23-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 Gene3D G3DSA:3.90.25.10 192 331 4.4E-48 T 23-04-2016 SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 Gene3D G3DSA:3.40.50.720 3 191 1.4E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04300 d7c03efb5ee50b4c26362022cbe2e73f 346 PANTHER PTHR10366:SF437 4 343 7.2E-194 T 23-04-2016 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 293 9.1E-92 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 PANTHER PTHR30304 1 293 4.4E-87 T 23-04-2016 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 SUPERFAMILY SSF51569 1 293 8.24E-96 T 23-04-2016 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 Gene3D G3DSA:3.20.20.70 1 293 2.7E-102 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 293 2.5E-120 T 23-04-2016 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 292 4.3E-95 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPYM18_RS08420 8c3d0bcdbf823318e3fb8b8300b10ff7 293 PIRSF PIRSF001359 1 293 9.0E-114 T 23-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 SPYM18_RS07720 78e0babaaba44a38c6d31a318f8df25b 146 SUPERFAMILY SSF103084 2 63 1.09E-25 T 23-04-2016 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 SPYM18_RS07720 78e0babaaba44a38c6d31a318f8df25b 146 SUPERFAMILY SSF103084 94 146 1.09E-25 T 23-04-2016 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 SPYM18_RS07720 78e0babaaba44a38c6d31a318f8df25b 146 Gene3D G3DSA:3.30.1330.70 2 146 4.3E-35 T 23-04-2016 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 SPYM18_RS07720 78e0babaaba44a38c6d31a318f8df25b 146 Pfam PF05866 Endodeoxyribonuclease RusA 7 143 9.0E-32 T 23-04-2016 IPR008822 Crossover junction endodeoxyribonuclease, RusA-like GO:0000287|GO:0006281|GO:0006310 SPYM18_RS01765 7c66e3f6a66fa18b42748020d33883b5 683 Pfam PF06605 Prophage endopeptidase tail 95 368 1.4E-13 T 23-04-2016 IPR010572 Prophage tail endopeptidase SPYM18_RS01765 7c66e3f6a66fa18b42748020d33883b5 683 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 28 359 2.5E-19 T 23-04-2016 IPR007119 Phage minor structural protein, N-terminal domain SPYM18_RS08945 a4b94a621f5b306de788216a71cfcbf7 533 Pfam PF05043 Mga helix-turn-helix domain 78 162 6.1E-23 T 23-04-2016 IPR007737 Mga helix-turn-helix domain SPYM18_RS08945 a4b94a621f5b306de788216a71cfcbf7 533 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 8 66 1.7E-18 T 23-04-2016 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain SPYM18_RS08945 a4b94a621f5b306de788216a71cfcbf7 533 Pfam PF08270 M protein trans-acting positive regulator (MGA) PRD domain 180 395 3.4E-58 T 23-04-2016 IPR013236 M protein trans-acting positive regulator (MGA), PRD domain SPYM18_RS08945 a4b94a621f5b306de788216a71cfcbf7 533 PANTHER PTHR42275 1 518 1.8E-23 T 23-04-2016 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 3.2E-48 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 3.2E-48 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 3.2E-48 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 3.2E-48 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 3.2E-48 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PANTHER PTHR23402 1 212 1.9E-65 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 201 6.2E-73 T 23-04-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PIRSF PIRSF015592 1 213 2.3E-84 T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 SUPERFAMILY SSF53182 1 204 2.35E-73 T 23-04-2016 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 Pfam PF01470 Pyroglutamyl peptidase 1 201 1.7E-97 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 199 39.093 T 23-04-2016 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-04-2016 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 PANTHER PTHR23402:SF1 1 212 1.9E-65 T 23-04-2016 SPYM18_RS02440 8473212995da02330fe8b813705b1ff0 215 Gene3D G3DSA:3.40.630.20 1 202 1.3E-69 T 23-04-2016 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 Gene3D G3DSA:2.30.310.10 1 167 3.8E-61 T 23-04-2016 SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 Pfam PF05670 Domain of unknown function (DUF814) 433 518 2.2E-25 T 23-04-2016 IPR008532 Domain of unknown function DUF814 SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 426 1.1E-144 T 23-04-2016 SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 PANTHER PTHR15239 1 385 8.9E-122 T 23-04-2016 SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 PANTHER PTHR15239 402 540 8.9E-122 T 23-04-2016 SPYM18_RS04320 88d65beb3ccb1c37a68690c83f7aef40 550 Gene3D G3DSA:3.40.970.40 239 273 3.6E-14 T 23-04-2016 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 486 499 - T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 Pfam PF02881 SRP54-type protein, helical bundle domain 227 292 3.5E-12 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 SMART SM00962 312 513 4.8E-114 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 PANTHER PTHR11564 212 513 1.2E-130 T 23-04-2016 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 Gene3D G3DSA:1.20.120.140 240 325 5.6E-25 T 23-04-2016 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 SUPERFAMILY SSF52540 313 512 1.23E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 SUPERFAMILY SSF47364 213 289 2.49E-18 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 Pfam PF00448 SRP54-type protein, GTPase domain 313 512 4.9E-76 T 23-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 SMART SM00963 215 296 3.2E-22 T 23-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 240 512 6.8E-107 T 23-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 239 513 62.034 T 23-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 Gene3D G3DSA:3.40.50.300 326 513 1.3E-77 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 SMART SM00382 311 501 4.1E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS02740 3456f26192a8ae684ee0191696bd376d 516 PANTHER PTHR11564:SF16 212 513 1.2E-130 T 23-04-2016 SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 PANTHER PTHR23029:SF29 5 220 3.2E-78 T 23-04-2016 SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 SMART SM00855 5 182 1.1E-19 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 SUPERFAMILY SSF53254 4 224 4.16E-50 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 PANTHER PTHR23029 5 220 3.2E-78 T 23-04-2016 SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 217 3.5E-33 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS07940 e2358883f6376dc0369e575e22d4faac 235 Gene3D G3DSA:3.40.50.1240 1 228 4.0E-53 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 Gene3D G3DSA:3.40.50.300 19 257 3.4E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 21 267 4.6E-121 T 23-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 Pfam PF00005 ABC transporter 37 191 6.3E-28 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 SUPERFAMILY SSF52540 18 254 8.99E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 PANTHER PTHR24220 22 265 7.2E-136 T 23-04-2016 SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 SMART SM00382 45 247 1.7E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05155 bd38e6224af64468563ab509afbc68e9 267 PANTHER PTHR24220:SF506 22 265 7.2E-136 T 23-04-2016 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 Pfam PF01381 Helix-turn-helix 9 62 5.2E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 SMART SM00530 8 62 0.0012 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 66 274 6.5E-46 T 23-04-2016 IPR010057 Transcription activator MutR, C-terminal SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 PANTHER PTHR37038 4 272 3.5E-34 T 23-04-2016 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 SUPERFAMILY SSF47413 4 63 1.72E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 PANTHER PTHR37038:SF1 4 272 3.5E-34 T 23-04-2016 SPYM18_RS02395 60341e78edc7f76890d51e454e00137c 288 Gene3D G3DSA:1.10.260.40 2 68 1.3E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 Gene3D G3DSA:3.40.50.300 2 233 3.9E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 SUPERFAMILY SSF52540 4 232 2.92E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 Pfam PF00005 ABC transporter 23 169 1.6E-34 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 273 4.3E-115 T 23-04-2016 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 PANTHER PTHR24220 6 233 9.2E-102 T 23-04-2016 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 PANTHER PTHR24220:SF435 6 233 9.2E-102 T 23-04-2016 SPYM18_RS09535 4867ddcf5321409ff92205b6180fa659 279 SMART SM00382 32 217 2.6E-16 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 Gene3D G3DSA:3.60.21.10 44 393 1.6E-21 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 PANTHER PTHR33393 10 300 5.9E-43 T 23-04-2016 SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 PANTHER PTHR33393:SF2 10 300 5.9E-43 T 23-04-2016 SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 53 299 4.5E-70 T 23-04-2016 IPR019079 Capsule synthesis protein, CapA SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 SMART SM00854 52 299 2.2E-87 T 23-04-2016 IPR019079 Capsule synthesis protein, CapA SPYM18_RS03790 9ce9b8ac6977c139afd4a0a449dd2e37 397 SUPERFAMILY SSF56300 53 305 8.35E-42 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS05825 0d3668af678ee29b4516118c1fc76ca8 174 PANTHER PTHR33795 1 173 8.2E-47 T 23-04-2016 SPYM18_RS05825 0d3668af678ee29b4516118c1fc76ca8 174 Gene3D G3DSA:1.10.10.60 62 154 4.1E-12 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS05825 0d3668af678ee29b4516118c1fc76ca8 174 Pfam PF13518 Helix-turn-helix domain 66 117 9.4E-6 T 23-04-2016 SPYM18_RS05825 0d3668af678ee29b4516118c1fc76ca8 174 SUPERFAMILY SSF46689 57 160 2.87E-15 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS05825 0d3668af678ee29b4516118c1fc76ca8 174 PANTHER PTHR33795:SF1 1 173 8.2E-47 T 23-04-2016 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 SUPERFAMILY SSF64182 3 310 6.8E-81 T 23-04-2016 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 PANTHER PTHR12112:SF17 4 309 5.1E-109 T 23-04-2016 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 Pfam PF01368 DHH family 3 147 2.4E-23 T 23-04-2016 IPR001667 DDH domain SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 PANTHER PTHR12112 4 309 5.1E-109 T 23-04-2016 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 Gene3D G3DSA:3.90.1640.10 2 189 5.9E-58 T 23-04-2016 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 311 43.57 T 23-04-2016 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 Pfam PF02833 DHHA2 domain 185 307 7.1E-16 T 23-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 SPYM18_RS01965 91d232bb53f0d4f0cf07a186e94b15a0 311 SMART SM01131 183 309 5.6E-56 T 23-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 SPYM18_RS06025 f3dc99deca9676aecd59d369aa9d5f1b 189 SUPERFAMILY SSF53098 107 188 6.45E-15 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06025 f3dc99deca9676aecd59d369aa9d5f1b 189 Pfam PF00665 Integrase core domain 113 188 2.3E-14 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS06025 f3dc99deca9676aecd59d369aa9d5f1b 189 PANTHER PTHR32552 6 188 3.9E-34 T 23-04-2016 SPYM18_RS06025 f3dc99deca9676aecd59d369aa9d5f1b 189 Gene3D G3DSA:3.30.420.10 108 188 5.9E-12 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06025 f3dc99deca9676aecd59d369aa9d5f1b 189 Pfam PF13276 HTH-like domain 32 83 1.7E-16 T 23-04-2016 IPR025948 HTH-like domain SPYM18_RS01795 28391534af0be2184f7254493bf61382 75 Pfam PF04531 Bacteriophage holin 2 74 3.2E-20 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS01795 28391534af0be2184f7254493bf61382 75 TIGRFAM TIGR01598 holin_phiLC3: holin, phage phi LC3 family 2 73 4.1E-19 T 23-04-2016 IPR006485 Bacteriophage holin SPYM18_RS01775 cdf0b3490713fd086ab760afd2c0dab1 634 Pfam PF07902 gp58-like protein 1 620 3.5E-279 T 23-04-2016 IPR012892 Gp58-like SPYM18_RS01775 cdf0b3490713fd086ab760afd2c0dab1 634 SUPERFAMILY SSF58113 158 292 3.92E-5 T 23-04-2016 SPYM18_RS09525 6a42d36e75ea92b63a2a69935b83c819 266 Pfam PF02361 Cobalt transport protein 14 236 8.4E-51 T 23-04-2016 IPR003339 ABC/ECF transporter, transmembrane component SPYM18_RS09525 6a42d36e75ea92b63a2a69935b83c819 266 PANTHER PTHR33514 1 266 4.0E-128 T 23-04-2016 SPYM18_RS09525 6a42d36e75ea92b63a2a69935b83c819 266 PANTHER PTHR33514:SF2 1 266 4.0E-128 T 23-04-2016 SPYM18_RS09525 6a42d36e75ea92b63a2a69935b83c819 266 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 37.098 T 23-04-2016 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 PANTHER PTHR30349:SF20 69 388 1.9E-28 T 23-04-2016 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 Gene3D G3DSA:1.10.443.10 196 375 1.3E-25 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 Pfam PF00589 Phage integrase family 199 373 1.0E-18 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 Gene3D G3DSA:1.10.150.130 71 166 3.9E-13 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 71 129 4.2E-12 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 PANTHER PTHR30349 69 388 1.9E-28 T 23-04-2016 SPYM18_RS07810 9a359db8c776a8c8ca12489c781358ee 388 SUPERFAMILY SSF56349 70 374 3.83E-47 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS07465 5c98a18bbde22ef58edbf881abd1fa51 344 Pfam PF05975 Bacterial ABC transporter protein EcsB 158 330 1.4E-41 T 23-04-2016 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPYM18_RS07465 5c98a18bbde22ef58edbf881abd1fa51 344 Pfam PF05975 Bacterial ABC transporter protein EcsB 3 151 1.7E-37 T 23-04-2016 IPR010288 Bacterial ABC transporter EcsB GO:0016021 SPYM18_RS07465 5c98a18bbde22ef58edbf881abd1fa51 344 PANTHER PTHR41253 1 344 2.3E-37 T 23-04-2016 SPYM18_RS01165 b0f5b406cb5d65efd5876b1972adc06c 295 Gene3D G3DSA:1.10.3720.10 8 285 1.1E-59 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01165 b0f5b406cb5d65efd5876b1972adc06c 295 PANTHER PTHR30193:SF6 7 295 1.1E-92 T 23-04-2016 SPYM18_RS01165 b0f5b406cb5d65efd5876b1972adc06c 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 283 4.2E-16 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01165 b0f5b406cb5d65efd5876b1972adc06c 295 SUPERFAMILY SSF161098 54 282 3.4E-57 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS01165 b0f5b406cb5d65efd5876b1972adc06c 295 PANTHER PTHR30193 7 295 1.1E-92 T 23-04-2016 SPYM18_RS07400 d5304b4b59f7ef3527bd2996857a7109 67 SUPERFAMILY SSF55008 1 66 3.01E-16 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPYM18_RS07400 d5304b4b59f7ef3527bd2996857a7109 67 Gene3D G3DSA:3.30.70.100 1 63 5.3E-19 T 23-04-2016 SPYM18_RS07400 d5304b4b59f7ef3527bd2996857a7109 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 23-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 SPYM18_RS07400 d5304b4b59f7ef3527bd2996857a7109 67 Pfam PF00403 Heavy-metal-associated domain 5 59 7.9E-15 T 23-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 Gene3D G3DSA:2.20.25.10 1 40 7.3E-21 T 23-04-2016 SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 SUPERFAMILY SSF57783 1 36 1.39E-12 T 23-04-2016 SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 110 5.6E-46 T 23-04-2016 IPR004624 PhnA protein SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 Pfam PF03831 PhnA domain 44 111 1.4E-32 T 23-04-2016 IPR013988 PhnA protein, C-terminal SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 Gene3D G3DSA:2.30.30.40 42 111 2.2E-36 T 23-04-2016 SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 Pfam PF08274 PhnA Zinc-Ribbon 2 31 9.3E-14 T 23-04-2016 IPR013987 PhnA protein, N-terminal SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 PANTHER PTHR30305 1 111 1.4E-73 T 23-04-2016 SPYM18_RS05305 f802da28a6f0e39e955fb7c848632a71 111 SUPERFAMILY SSF82057 39 111 1.65E-27 T 23-04-2016 SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 SMART SM00382 28 217 1.1E-17 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 PANTHER PTHR24220 5 254 6.4E-139 T 23-04-2016 SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 Pfam PF00005 ABC transporter 20 167 2.6E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 Gene3D G3DSA:3.40.50.300 5 233 1.3E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 PANTHER PTHR24220:SF438 5 254 6.4E-139 T 23-04-2016 SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 SUPERFAMILY SSF52540 3 231 7.6E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01990 ae6095bb76994a1a4506b449a079366c 260 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 PANTHER PTHR10513:SF17 1 203 9.3E-54 T 23-04-2016 SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 PANTHER PTHR10513 1 203 9.3E-54 T 23-04-2016 SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 Gene3D G3DSA:3.40.50.300 1 205 5.8E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 SUPERFAMILY SSF52540 1 208 5.05E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 Pfam PF01712 Deoxynucleoside kinase 3 207 8.4E-59 T 23-04-2016 IPR031314 Deoxynucleoside kinase domain SPYM18_RS00730 62caf7ff6ee22cf905d727621c603fdc 213 PIRSF PIRSF000705 1 212 3.7E-56 T 23-04-2016 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 SUPERFAMILY SSF52833 1 71 6.61E-20 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 2 72 6.0E-36 T 23-04-2016 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 PANTHER PTHR34386 2 72 3.3E-17 T 23-04-2016 SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 Pfam PF00462 Glutaredoxin 2 57 2.3E-14 T 23-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 PANTHER PTHR34386:SF3 2 72 3.3E-17 T 23-04-2016 SPYM18_RS06000 5f34ba91db2043d773e999a99a6ffff4 72 Gene3D G3DSA:3.40.30.10 1 71 1.1E-25 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 PANTHER PTHR24220 10 252 2.2E-87 T 23-04-2016 SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 PANTHER PTHR24220:SF534 10 252 2.2E-87 T 23-04-2016 SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 SUPERFAMILY SSF52540 18 233 2.3E-49 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 SMART SM00382 34 229 1.9E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 Gene3D G3DSA:3.40.50.300 2 237 1.7E-56 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04335 e0f21944732d03ab44f6773f331a1e21 252 Pfam PF00005 ABC transporter 25 180 2.1E-27 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08365 cdc67b3eb74ac7c450a44650a4db5c48 76 Pfam PF07288 Protein of unknown function (DUF1447) 2 75 4.0E-30 T 23-04-2016 IPR009907 Protein of unknown function DUF1447 SPYM18_RS08365 cdc67b3eb74ac7c450a44650a4db5c48 76 Hamap MF_01553 UPF0356 protein . 1 76 22.036 T 23-04-2016 IPR009907 Protein of unknown function DUF1447 SPYM18_RS08365 cdc67b3eb74ac7c450a44650a4db5c48 76 PANTHER PTHR41306 2 76 1.0E-19 T 23-04-2016 IPR009907 Protein of unknown function DUF1447 SPYM18_RS08365 cdc67b3eb74ac7c450a44650a4db5c48 76 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 75 3.0E-37 T 23-04-2016 IPR009907 Protein of unknown function DUF1447 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 1.2E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.2E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 1.2E-5 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 120 3.5E-33 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 PANTHER PTHR30266 1 120 3.6E-38 T 23-04-2016 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 PANTHER PTHR30266:SF2 1 120 3.6E-38 T 23-04-2016 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 Gene3D G3DSA:1.20.5.220 105 119 1.1E-5 T 23-04-2016 IPR029027 Single alpha-helix domain SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 117 1.5E-36 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS03625 955134cf24d8cdff5dd2ad7490eb0d1f 120 SUPERFAMILY SSF81330 10 114 1.7E-28 T 23-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 10 76 1.0E-11 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 PIRSF PIRSF039114 1 466 1.7E-248 T 23-04-2016 IPR022879 V-type ATP synthase regulatory subunit B/beta SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 PANTHER PTHR15184 6 458 1.7E-278 T 23-04-2016 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 SUPERFAMILY SSF47917 364 421 6.54E-6 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 4 460 60.138 T 23-04-2016 IPR022879 V-type ATP synthase regulatory subunit B/beta SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 Gene3D G3DSA:3.40.50.300 78 355 4.9E-102 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 Gene3D G3DSA:1.10.1140.10 365 430 4.3E-6 T 23-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 133 351 1.6E-67 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 SUPERFAMILY SSF52540 80 355 3.23E-83 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 23-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS00865 ff7998e67370834b35e12c46db4a40ca 471 PANTHER PTHR15184:SF11 6 458 1.7E-278 T 23-04-2016 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 SUPERFAMILY SSF46589 813 877 3.03E-16 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 SUPERFAMILY SSF50677 192 343 3.66E-61 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 429 7.8E-161 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 559 2.2E-53 T 23-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Gene3D G3DSA:3.90.740.10 196 337 6.9E-50 T 23-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 TIGRFAM TIGR00422 valS: valine--tRNA ligase 6 860 0.0 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PANTHER PTHR11946 809 876 0.0 T 23-04-2016 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PANTHER PTHR11946 1 789 0.0 T 23-04-2016 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 3.2E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PRINTS PR00986 Valyl-tRNA synthetase signature 232 249 3.2E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PRINTS PR00986 Valyl-tRNA synthetase signature 439 460 3.2E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PRINTS PR00986 Valyl-tRNA synthetase signature 347 360 3.2E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PRINTS PR00986 Valyl-tRNA synthetase signature 471 489 3.2E-37 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Gene3D G3DSA:1.10.730.10 559 744 8.3E-56 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 SUPERFAMILY SSF47323 570 828 1.5E-66 T 23-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Hamap MF_02004 Valine--tRNA ligase [valS]. 4 878 15.706 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PANTHER PTHR11946:SF5 809 876 0.0 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 PANTHER PTHR11946:SF5 1 789 0.0 T 23-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Gene3D G3DSA:3.40.50.620 7 195 3.0E-140 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Gene3D G3DSA:3.40.50.620 342 558 3.0E-140 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Gene3D G3DSA:1.10.287.380 806 875 2.7E-5 T 23-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 SUPERFAMILY SSF52374 2 194 1.41E-140 T 23-04-2016 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 SUPERFAMILY SSF52374 342 569 1.41E-140 T 23-04-2016 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Pfam PF08264 Anticodon-binding domain of tRNA 609 753 5.2E-40 T 23-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 813 877 3.0E-17 T 23-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 SPYM18_RS06805 07b6cc143c89b7759cffcc61b718f73a 882 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 45 56 - T 23-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS00065 ed015395716b6036a61d47650a9875ed 463 PANTHER PTHR11785:SF342 11 459 3.3E-130 T 23-04-2016 SPYM18_RS00065 ed015395716b6036a61d47650a9875ed 463 Pfam PF13520 Amino acid permease 21 439 1.3E-47 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS00065 ed015395716b6036a61d47650a9875ed 463 PANTHER PTHR11785 11 459 3.3E-130 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS00065 ed015395716b6036a61d47650a9875ed 463 PIRSF PIRSF006060 6 463 1.6E-77 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS03890 13e60c40fb86e8ee7698a278a3575384 133 SUPERFAMILY SSF50475 1 117 1.96E-22 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 SPYM18_RS03890 13e60c40fb86e8ee7698a278a3575384 133 Gene3D G3DSA:2.30.110.10 1 116 3.8E-33 T 23-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 SPYM18_RS03890 13e60c40fb86e8ee7698a278a3575384 133 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 87 3.2E-17 T 23-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 SPYM18_RS03890 13e60c40fb86e8ee7698a278a3575384 133 PANTHER PTHR40660 1 129 1.6E-29 T 23-04-2016 SPYM18_RS03955 17bafb806e66657478ca1d6ec42766a9 72 SUPERFAMILY SSF53098 4 69 3.22E-7 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS03955 17bafb806e66657478ca1d6ec42766a9 72 Pfam PF13333 Integrase core domain 14 70 1.4E-17 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS03955 17bafb806e66657478ca1d6ec42766a9 72 Gene3D G3DSA:3.30.420.10 2 55 4.4E-6 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 167 1.5E-35 T 23-04-2016 IPR010021 HAD-superfamily phosphatase, YqeG-like SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 PANTHER PTHR19288 7 159 2.0E-29 T 23-04-2016 SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 30 139 3.0E-17 T 23-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 PANTHER PTHR19288:SF25 7 159 2.0E-29 T 23-04-2016 SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 SUPERFAMILY SSF56784 5 153 1.29E-26 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 Gene3D G3DSA:3.40.50.1000 16 159 2.1E-26 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS01400 8299d98daee0d5c9012dd85c60463835 175 Pfam PF13419 Haloacid dehalogenase-like hydrolase 49 137 1.7E-11 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 23-04-2016 IPR001014 Ribosomal protein L23/L25, conserved site SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 95 21.75 T 23-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 SUPERFAMILY SSF54189 1 91 3.06E-29 T 23-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 Pfam PF00276 Ribosomal protein L23 5 88 2.0E-29 T 23-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 Gene3D G3DSA:3.30.70.330 1 93 1.6E-32 T 23-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 SPYM18_RS00380 1bd929cdf9683445e27e4454237a23ac 98 PANTHER PTHR11620 1 93 7.2E-31 T 23-04-2016 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 SUPERFAMILY SSF51246 332 446 7.32E-39 T 23-04-2016 IPR011054 Rudiment single hybrid motif SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 1.6E-36 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Gene3D G3DSA:3.30.1490.20 130 202 1.2E-29 T 23-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 SMART SM00878 337 444 1.1E-54 T 23-04-2016 IPR005482 Biotin carboxylase, C-terminal SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Gene3D G3DSA:3.30.470.20 206 447 1.2E-96 T 23-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 PANTHER PTHR18866 1 445 4.1E-288 T 23-04-2016 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 SUPERFAMILY SSF56059 83 353 1.94E-71 T 23-04-2016 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.8E-45 T 23-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Gene3D G3DSA:3.40.50.20 1 129 1.3E-50 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 9.1E-203 T 23-04-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 SUPERFAMILY SSF52440 1 113 1.22E-48 T 23-04-2016 IPR016185 Pre-ATP-grasp domain SPYM18_RS07855 a8344a3bcfb89333056392eb04b20aa0 454 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 2.5E-76 T 23-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 SPYM18_RS02500 84623c96f147f85e377ff6539ef054c7 333 Gene3D G3DSA:3.30.420.10 179 314 4.2E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02500 84623c96f147f85e377ff6539ef054c7 333 PANTHER PTHR10948 4 328 2.2E-82 T 23-04-2016 SPYM18_RS02500 84623c96f147f85e377ff6539ef054c7 333 SUPERFAMILY SSF53098 176 314 6.26E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02500 84623c96f147f85e377ff6539ef054c7 333 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS02500 84623c96f147f85e377ff6539ef054c7 333 Gene3D G3DSA:1.10.10.60 7 46 6.0E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 SUPERFAMILY SSF47240 26 167 4.43E-39 T 23-04-2016 IPR009078 Ferritin-like superfamily SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PIRSF PIRSF005900 9 174 3.6E-42 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 ProSitePatterns PS00818 Dps protein family signature 1. 50 66 - T 23-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PANTHER PTHR30295 7 173 1.1E-45 T 23-04-2016 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 Pfam PF00210 Ferritin-like domain 30 169 1.5E-27 T 23-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PANTHER PTHR30295:SF6 7 173 1.1E-45 T 23-04-2016 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 50 66 2.4E-13 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 74 90 2.4E-13 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 147 165 2.4E-13 T 23-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 SPYM18_RS06670 94ede2ab82e89b36e22ca5a3321f4c3c 175 Gene3D G3DSA:1.20.1260.10 21 170 1.3E-50 T 23-04-2016 IPR012347 Ferritin-related SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 PRINTS PR00127 Clp protease catalytic subunit P signature 43 63 3.4E-8 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 PRINTS PR00127 Clp protease catalytic subunit P signature 151 170 3.4E-8 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 PRINTS PR00127 Clp protease catalytic subunit P signature 74 91 3.4E-8 T 23-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 SUPERFAMILY SSF52096 21 176 3.62E-38 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 PANTHER PTHR10381 40 173 5.0E-30 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 Gene3D G3DSA:3.90.226.10 17 183 5.7E-39 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 Pfam PF00574 Clp protease 28 174 1.4E-29 T 23-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA SPYM18_RS03250 0fd31b98335fa39d3aada8468fee64f3 221 PANTHER PTHR10381:SF23 40 173 5.0E-30 T 23-04-2016 SPYM18_RS05385 e3976d1113a77f9831e03691c8c78b94 230 SUPERFAMILY SSF54171 167 218 7.19E-6 T 23-04-2016 IPR016177 DNA-binding domain GO:0003677 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 56.964 T 23-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Gene3D G3DSA:3.40.50.300 80 349 1.1E-108 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 SUPERFAMILY SSF50615 2 78 2.07E-22 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 23-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Gene3D G3DSA:2.40.10.170 2 78 6.0E-29 T 23-04-2016 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Gene3D G3DSA:1.10.1140.10 351 466 1.8E-50 T 23-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 SUPERFAMILY SSF52540 81 353 1.41E-89 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 3.7E-252 T 23-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 2.3E-21 T 23-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 SUPERFAMILY SSF47917 351 466 1.62E-50 T 23-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 SMART SM00382 147 332 1.8E-7 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 PANTHER PTHR15184:SF8 1 466 0.0 T 23-04-2016 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 1.9E-67 T 23-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 SPYM18_RS03540 2f1dc2b380e7672912ef3578e3caa1f6 468 PANTHER PTHR15184 1 466 0.0 T 23-04-2016 SPYM18_RS02935 8d3da407a89ed1d41fe4b0238ef91c1e 128 Gene3D G3DSA:2.40.128.20 2 127 1.6E-23 T 23-04-2016 IPR012674 Calycin SPYM18_RS02935 8d3da407a89ed1d41fe4b0238ef91c1e 128 SUPERFAMILY SSF50814 1 127 1.26E-35 T 23-04-2016 IPR011038 Calycin-like SPYM18_RS02935 8d3da407a89ed1d41fe4b0238ef91c1e 128 Pfam PF09148 Domain of unknown function (DUF1934) 4 124 3.6E-20 T 23-04-2016 IPR015231 Protein of unknown function DUF1934 SPYM18_RS09060 da2ae198f0e56fec4aec2e5e81e4b8d3 326 PANTHER PTHR34294 1 319 6.9E-111 T 23-04-2016 SPYM18_RS09060 da2ae198f0e56fec4aec2e5e81e4b8d3 326 Gene3D G3DSA:3.40.50.1360 54 317 3.9E-76 T 23-04-2016 SPYM18_RS09060 da2ae198f0e56fec4aec2e5e81e4b8d3 326 PANTHER PTHR34294:SF2 1 319 6.9E-111 T 23-04-2016 SPYM18_RS09060 da2ae198f0e56fec4aec2e5e81e4b8d3 326 Pfam PF04198 Putative sugar-binding domain 59 314 4.5E-84 T 23-04-2016 IPR007324 Sugar-binding domain, putative GO:0030246 SPYM18_RS09060 da2ae198f0e56fec4aec2e5e81e4b8d3 326 SUPERFAMILY SSF100950 59 316 1.19E-68 T 23-04-2016 SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 Gene3D G3DSA:1.20.1250.20 213 395 9.7E-21 T 23-04-2016 SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 Gene3D G3DSA:1.20.1250.20 4 188 1.7E-22 T 23-04-2016 SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 SUPERFAMILY SSF103473 3 397 4.84E-56 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 Pfam PF07690 Major Facilitator Superfamily 19 362 8.3E-38 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 PANTHER PTHR11360:SF135 2 392 1.0E-124 T 23-04-2016 SPYM18_RS06070 0f51ce9c2ba9e4c702497796bc56a863 398 PANTHER PTHR11360 2 392 1.0E-124 T 23-04-2016 SPYM18_RS07270 624c74cb7e8fbf16115525762fd3a34f 499 Pfam PF05043 Mga helix-turn-helix domain 78 161 3.5E-24 T 23-04-2016 IPR007737 Mga helix-turn-helix domain SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 PANTHER PTHR23089 1 138 1.2E-65 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 PRINTS PR00332 Histidine triad family signature 93 103 6.1E-17 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 PRINTS PR00332 Histidine triad family signature 5 21 6.1E-17 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 PRINTS PR00332 Histidine triad family signature 26 44 6.1E-17 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 Pfam PF01230 HIT domain 12 107 1.3E-26 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 PANTHER PTHR23089:SF14 1 138 1.2E-65 T 23-04-2016 SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 SUPERFAMILY SSF54197 2 130 2.17E-41 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 SPYM18_RS07475 29f33ad634411f8c80ce0a8ed9c36374 139 Gene3D G3DSA:3.30.428.10 1 110 5.8E-42 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 SPYM18_RS08025 a13e7a490b9a999263fe46173ca87ec9 226 PANTHER PTHR33514 2 225 1.8E-13 T 23-04-2016 SPYM18_RS08025 a13e7a490b9a999263fe46173ca87ec9 226 Pfam PF02361 Cobalt transport protein 2 190 5.4E-14 T 23-04-2016 IPR003339 ABC/ECF transporter, transmembrane component SPYM18_RS07555 890108ecdff100862c1cd5888e478c30 671 Pfam PF07902 gp58-like protein 1 643 6.3E-281 T 23-04-2016 IPR012892 Gp58-like SPYM18_RS07555 890108ecdff100862c1cd5888e478c30 671 SUPERFAMILY SSF58113 182 346 6.93E-6 T 23-04-2016 SPYM18_RS01770 93d583da19bded6324113e5be07c1883 335 Pfam PF07212 Hyaluronidase protein (HylP) 56 333 2.2E-145 T 23-04-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 SPYM18_RS01770 93d583da19bded6324113e5be07c1883 335 SUPERFAMILY SSF69349 7 332 6.36E-129 T 23-04-2016 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Pfam PF00817 impB/mucB/samB family 17 167 3.4E-51 T 23-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Gene3D G3DSA:3.30.1490.100 254 356 1.9E-27 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 SUPERFAMILY SSF56672 5 247 6.76E-91 T 23-04-2016 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 SUPERFAMILY SSF100879 251 352 3.14E-23 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Hamap MF_01113 DNA polymerase IV [dinB]. 11 364 37.853 T 23-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Gene3D G3DSA:3.30.70.270 79 177 2.1E-33 T 23-04-2016 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Pfam PF11799 impB/mucB/samB family C-terminal domain 248 356 5.7E-18 T 23-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Pfam PF11798 IMS family HHH motif 180 210 7.3E-8 T 23-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 PANTHER PTHR11076 1 355 3.1E-133 T 23-04-2016 SPYM18_RS08240 a309a8d29315c36e8a646118c7fc8653 364 Gene3D G3DSA:1.10.150.20 180 248 9.3E-23 T 23-04-2016 SPYM18_RS04665 89eb9850993957b21bf4c6b0f0cd5dd4 115 SUPERFAMILY SSF160800 1 112 1.57E-43 T 23-04-2016 IPR014965 Putative amino acid metabolism SPYM18_RS04665 89eb9850993957b21bf4c6b0f0cd5dd4 115 Pfam PF08866 Putative amino acid metabolism 1 110 3.4E-44 T 23-04-2016 IPR014965 Putative amino acid metabolism SPYM18_RS04665 89eb9850993957b21bf4c6b0f0cd5dd4 115 Gene3D G3DSA:3.30.1820.10 1 112 1.2E-47 T 23-04-2016 IPR014965 Putative amino acid metabolism SPYM18_RS07785 15a5390bc25a4608cc7309677cbb9222 239 PANTHER PTHR36180 1 201 1.4E-49 T 23-04-2016 SPYM18_RS07785 15a5390bc25a4608cc7309677cbb9222 239 Pfam PF08346 AntA/AntB antirepressor 17 85 7.0E-19 T 23-04-2016 IPR013557 AntA/AntB antirepressor SPYM18_RS07785 15a5390bc25a4608cc7309677cbb9222 239 PANTHER PTHR36180:SF1 1 201 1.4E-49 T 23-04-2016 SPYM18_RS07785 15a5390bc25a4608cc7309677cbb9222 239 Pfam PF03374 Phage antirepressor protein KilAC domain 124 234 8.5E-35 T 23-04-2016 IPR005039 Antirepressor protein, C-terminal GO:0003677 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 Pfam PF01026 TatD related DNase 11 261 3.1E-80 T 23-04-2016 IPR001130 TatD family GO:0016788 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 197 213 - T 23-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 Gene3D G3DSA:3.20.20.140 5 262 2.0E-92 T 23-04-2016 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 PANTHER PTHR10060 10 263 1.4E-116 T 23-04-2016 IPR001130 TatD family GO:0016788 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 SUPERFAMILY SSF51556 9 262 4.2E-89 T 23-04-2016 IPR032466 Metal-dependent hydrolase SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 PIRSF PIRSF005902 1 263 3.2E-81 T 23-04-2016 IPR001130 TatD family GO:0016788 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 PANTHER PTHR10060:SF20 10 263 1.4E-116 T 23-04-2016 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 10 18 - T 23-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 SPYM18_RS01200 0278658c8bff31f60e5c133b84d71020 263 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 10 261 1.0E-81 T 23-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 Pfam PF09397 Ftsk gamma domain 739 799 6.6E-28 T 23-04-2016 IPR018541 FtsK gamma domain SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 SMART SM00382 473 655 3.1E-4 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 Gene3D G3DSA:3.40.50.300 413 700 2.2E-79 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 SUPERFAMILY SSF52540 412 706 4.32E-41 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 PANTHER PTHR22683:SF41 15 798 1.2E-231 T 23-04-2016 SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 PANTHER PTHR22683 15 798 1.2E-231 T 23-04-2016 SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 Pfam PF01580 FtsK/SpoIIIE family 449 634 1.6E-56 T 23-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 SUPERFAMILY SSF46785 739 800 4.08E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS02190 696c6d3f430e24384caa3b46029ab956 801 SMART SM00843 737 801 1.6E-33 T 23-04-2016 IPR018541 FtsK gamma domain SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 Hamap MF_01103 UPF0291 protein . 1 59 15.683 T 23-04-2016 IPR009242 Protein of unknown function DUF896 SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 Gene3D G3DSA:1.10.287.540 1 59 4.7E-27 T 23-04-2016 IPR023218 UPF0291 structural domain SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 67 2.0E-28 T 23-04-2016 IPR009242 Protein of unknown function DUF896 SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 SUPERFAMILY SSF158221 2 41 1.02E-12 T 23-04-2016 SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 PANTHER PTHR37300 1 78 1.3E-37 T 23-04-2016 SPYM18_RS07300 76dc8d5ca37ddcc6e156bbd07e6b5af5 85 PANTHER PTHR37300:SF1 1 78 1.3E-37 T 23-04-2016 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 Pfam PF01522 Polysaccharide deacetylase 236 349 1.6E-38 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 SUPERFAMILY SSF88713 231 422 4.94E-66 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 PANTHER PTHR10587 241 421 1.2E-60 T 23-04-2016 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 Gene3D G3DSA:3.20.20.370 214 422 6.7E-73 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 SUPERFAMILY SSF144015 34 237 1.19E-58 T 23-04-2016 SPYM18_RS05980 db919fae35f5f1c76d4bf2818e21ff66 424 PIRSF PIRSF037479 1 424 2.6E-159 T 23-04-2016 IPR017219 Peptidoglycan GlcNAc deacetylase SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 Gene3D G3DSA:1.10.1790.10 314 409 1.0E-21 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 SUPERFAMILY SSF63520 310 409 8.37E-23 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 Pfam PF08279 HTH domain 98 152 2.6E-5 T 23-04-2016 IPR013196 Helix-turn-helix, type 11 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 Gene3D G3DSA:1.10.10.10 90 153 4.9E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 PANTHER PTHR36203:SF1 4 501 3.5E-93 T 23-04-2016 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 PANTHER PTHR36203 4 501 3.5E-93 T 23-04-2016 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 Pfam PF00874 PRD domain 217 298 7.1E-5 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS00970 f3c6e482964c56185414b95dc3eb7a1f 548 Pfam PF00874 PRD domain 322 409 1.7E-22 T 23-04-2016 IPR011608 PRD domain GO:0006355 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 PANTHER PTHR12725 2 267 2.9E-40 T 23-04-2016 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 Gene3D G3DSA:3.40.50.1000 90 233 4.9E-36 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 202 1.3E-25 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 197 3.5E-16 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 PANTHER PTHR12725:SF78 2 267 2.9E-40 T 23-04-2016 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 SUPERFAMILY SSF56784 1 232 1.08E-43 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.9E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 3.9E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS02845 63fb44f0bcad6ace8559aeaa8fd56dcf 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 3.9E-7 T 23-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 Gene3D G3DSA:1.10.150.130 60 158 6.5E-14 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 PANTHER PTHR30349 59 355 5.5E-41 T 23-04-2016 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 Pfam PF14657 AP2-like DNA-binding integrase domain 15 55 2.5E-6 T 23-04-2016 IPR028259 AP2-like integrase, N-terminal domain SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 SUPERFAMILY SSF56349 60 344 5.0E-64 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 Pfam PF00589 Phage integrase family 169 341 5.5E-26 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 61 117 1.7E-14 T 23-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 Gene3D G3DSA:1.10.443.10 167 346 2.1E-39 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS05680 ed9af166edbefb937267e81a41ac6339 362 PANTHER PTHR30349:SF20 59 355 5.5E-41 T 23-04-2016 SPYM18_RS05410 61383855fe50950db7dd2491bb9b6884 203 Pfam PF07104 Protein of unknown function (DUF1366) 5 90 1.6E-5 T 23-04-2016 IPR009796 Protein of unknown function DUF1366 SPYM18_RS07615 dbd3184917ce965040f03e260cdbb966 272 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 5 214 4.5E-23 T 23-04-2016 SPYM18_RS07615 dbd3184917ce965040f03e260cdbb966 272 SUPERFAMILY SSF56563 1 267 2.48E-35 T 23-04-2016 SPYM18_RS07615 dbd3184917ce965040f03e260cdbb966 272 Pfam PF05065 Phage capsid family 14 259 6.9E-7 T 23-04-2016 IPR024455 Phage capsid SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 Pfam PF01168 Alanine racemase, N-terminal domain 28 222 4.4E-15 T 23-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 PANTHER PTHR10146 1 222 4.3E-71 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 PIRSF PIRSF004848 3 223 1.4E-61 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 SUPERFAMILY SSF51419 1 222 6.8E-64 T 23-04-2016 IPR029066 PLP-binding barrel SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 Gene3D G3DSA:3.20.20.10 2 222 3.4E-67 T 23-04-2016 IPR029066 PLP-binding barrel SPYM18_RS06615 35220b47b9f56559d9114c9db9846664 223 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 3 222 7.0E-46 T 23-04-2016 IPR011078 Uncharacterised protein family UPF0001 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 SUPERFAMILY SSF53328 1 177 3.53E-53 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 Gene3D G3DSA:3.40.50.170 1 177 1.2E-63 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 2 180 28.654 T 23-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 177 5.4E-61 T 23-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 PANTHER PTHR10520 1 177 2.4E-77 T 23-04-2016 SPYM18_RS00285 232573d37491bdbf0f072ea32beee366 184 Pfam PF00551 Formyl transferase 1 174 8.1E-51 T 23-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 PANTHER PTHR11895 503 570 4.9E-66 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 PANTHER PTHR11895 41 475 4.9E-66 T 23-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 SUPERFAMILY SSF75304 89 473 7.59E-92 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 SUPERFAMILY SSF75304 506 562 7.59E-92 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 Pfam PF01425 Amidase 121 553 5.8E-62 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 Gene3D G3DSA:3.90.1300.10 89 566 5.7E-87 T 23-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 PANTHER PTHR11895:SF35 503 570 4.9E-66 T 23-04-2016 SPYM18_RS08850 b7b2b6e3cd38a3d10442c5e70ab8c457 657 PANTHER PTHR11895:SF35 41 475 4.9E-66 T 23-04-2016 SPYM18_RS03430 eea41c327434076e00264a390bbbfbf4 574 PANTHER PTHR41314 3 574 3.6E-143 T 23-04-2016 SPYM18_RS03430 eea41c327434076e00264a390bbbfbf4 574 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 6 568 26.046 T 23-04-2016 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 SPYM18_RS03430 eea41c327434076e00264a390bbbfbf4 574 Pfam PF06160 Septation ring formation regulator, EzrA 8 565 1.5E-182 T 23-04-2016 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 Gene3D G3DSA:3.10.290.10 10 58 2.1E-14 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 Pfam PF00849 RNA pseudouridylate synthase 83 235 1.2E-35 T 23-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 PANTHER PTHR11079 11 296 1.3E-126 T 23-04-2016 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 SUPERFAMILY SSF55120 67 294 1.27E-77 T 23-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 SMART SM00363 10 69 1.7E-9 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 8 294 3.6E-96 T 23-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 PANTHER PTHR11079:SF71 11 296 1.3E-126 T 23-04-2016 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 Pfam PF01479 S4 domain 10 55 5.5E-11 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 23-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 SPYM18_RS03825 a7f8c2293d9a87ce89cfc841b3a80313 296 SUPERFAMILY SSF55174 10 95 4.04E-12 T 23-04-2016 SPYM18_RS05060 6764c63daee3250bd719ed114c305ed4 399 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 8 345 1.8E-53 T 23-04-2016 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 SPYM18_RS05060 6764c63daee3250bd719ed114c305ed4 399 PANTHER PTHR22893:SF14 1 356 3.4E-72 T 23-04-2016 SPYM18_RS05060 6764c63daee3250bd719ed114c305ed4 399 PANTHER PTHR22893 1 356 3.4E-72 T 23-04-2016 SPYM18_RS05060 6764c63daee3250bd719ed114c305ed4 399 Gene3D G3DSA:3.20.20.70 1 351 3.5E-81 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS05060 6764c63daee3250bd719ed114c305ed4 399 SUPERFAMILY SSF51395 5 347 7.33E-80 T 23-04-2016 SPYM18_RS09475 4ffbd7eb666ae492a00543460baa8528 90 PANTHER PTHR40026:SF1 6 90 3.3E-22 T 23-04-2016 IPR009366 Protein Veg GO:0042710 SPYM18_RS09475 4ffbd7eb666ae492a00543460baa8528 90 PIRSF PIRSF037257 1 90 1.1E-26 T 23-04-2016 IPR009366 Protein Veg GO:0042710 SPYM18_RS09475 4ffbd7eb666ae492a00543460baa8528 90 PANTHER PTHR40026 6 90 3.3E-22 T 23-04-2016 SPYM18_RS09475 4ffbd7eb666ae492a00543460baa8528 90 Pfam PF06257 Biofilm formation stimulator VEG 10 86 1.2E-23 T 23-04-2016 IPR009366 Protein Veg GO:0042710 SPYM18_RS09475 4ffbd7eb666ae492a00543460baa8528 90 Gene3D G3DSA:2.30.30.100 1 89 4.6E-29 T 23-04-2016 SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 SUPERFAMILY SSF55729 169 244 1.09E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 SUPERFAMILY SSF55729 301 393 1.09E-24 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 Gene3D G3DSA:3.40.630.30 173 243 1.9E-38 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 Gene3D G3DSA:3.40.630.30 300 374 1.9E-38 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 PANTHER PTHR36174:SF1 1 407 1.7E-87 T 23-04-2016 SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 SUPERFAMILY SSF55729 8 166 6.36E-43 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 Gene3D G3DSA:3.40.630.30 6 172 1.4E-55 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 PANTHER PTHR36174 1 407 1.7E-87 T 23-04-2016 SPYM18_RS04995 c142e3bdaa9dd4b0a3b8669c19969e8c 407 Pfam PF02388 FemAB family 12 398 2.9E-128 T 23-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 PANTHER PTHR34137 1 70 9.2E-22 T 23-04-2016 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 Pfam PF02609 Exonuclease VII small subunit 7 56 3.0E-19 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 48 3.0E-20 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 SUPERFAMILY SSF116842 3 69 1.03E-18 T 23-04-2016 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 14.376 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 Gene3D G3DSA:1.10.287.1040 3 69 2.9E-23 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 1.5E-22 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06535 0bdebf152e92df1b4ec851adf857ec30 71 PIRSF PIRSF006488 1 70 3.0E-18 T 23-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 SPYM18_RS06605 4499c578fe418050ea458752ae73fd50 84 PANTHER PTHR33219 1 84 1.0E-13 T 23-04-2016 SPYM18_RS06605 4499c578fe418050ea458752ae73fd50 84 Pfam PF02325 YGGT family 11 79 6.0E-17 T 23-04-2016 IPR003425 CCB3/YggT GO:0016020 SPYM18_RS00610 a1659afe9d35ae0cc4e873cc6801bf5c 271 Gene3D G3DSA:1.10.3470.10 45 259 2.2E-5 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS00610 a1659afe9d35ae0cc4e873cc6801bf5c 271 SUPERFAMILY SSF81345 4 259 1.83E-36 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS00610 a1659afe9d35ae0cc4e873cc6801bf5c 271 PANTHER PTHR30477:SF0 1 270 1.0E-82 T 23-04-2016 SPYM18_RS00610 a1659afe9d35ae0cc4e873cc6801bf5c 271 Pfam PF00950 ABC 3 transport family 6 261 3.1E-74 T 23-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 SPYM18_RS00610 a1659afe9d35ae0cc4e873cc6801bf5c 271 PANTHER PTHR30477 1 270 1.0E-82 T 23-04-2016 SPYM18_RS08540 036c89767e6a2c3a99ef16f45e12d27c 520 SUPERFAMILY SSF55874 389 508 1.08E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 6.4E-7 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 6.4E-7 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 PANTHER PTHR10229 6 399 1.2E-138 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 Gene3D G3DSA:3.40.50.300 199 355 1.3E-29 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 SUPERFAMILY SSF52540 199 379 2.02E-32 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 PIRSF PIRSF006809 2 412 3.2E-139 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 Pfam PF13167 GTP-binding GTPase N-terminal 27 113 8.2E-32 T 23-04-2016 IPR025121 GTPase HflX, N-terminal SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 352 1.1E-132 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 Hamap MF_00900 GTPase HflX [hflX]. 28 384 43.513 T 23-04-2016 IPR016496 GTPase HflX GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 Pfam PF01926 50S ribosome-binding GTPase 200 319 6.5E-17 T 23-04-2016 IPR006073 GTP binding domain GO:0005525 SPYM18_RS04235 9af1d60b38e2bc9ee235b76e25e06771 412 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 5.2E-29 T 23-04-2016 IPR032305 GTP-binding protein, middle domain SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 Gene3D G3DSA:3.20.20.70 2 218 1.6E-95 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 33 47 - T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 135 157 - T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 215 3.6E-83 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 PIRSF PIRSF001461 1 220 2.2E-87 T 23-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 PANTHER PTHR11749 2 219 7.6E-119 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 Pfam PF00834 Ribulose-phosphate 3 epimerase family 5 202 2.3E-77 T 23-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 SPYM18_RS01220 3047aacbbdb6314c59b936dc4ad891d6 220 SUPERFAMILY SSF51366 4 216 9.42E-72 T 23-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 9 383 3.2E-98 T 23-04-2016 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 PANTHER PTHR10572:SF6 7 424 1.5E-140 T 23-04-2016 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 Gene3D G3DSA:3.90.770.10 230 371 1.6E-88 T 23-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 Gene3D G3DSA:3.90.770.10 7 117 1.6E-88 T 23-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 Gene3D G3DSA:3.30.70.420 118 216 1.6E-38 T 23-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 SUPERFAMILY SSF56542 225 424 9.94E-102 T 23-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 SUPERFAMILY SSF56542 8 120 9.94E-102 T 23-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 16 383 7.1E-108 T 23-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 PANTHER PTHR10572 7 424 1.5E-140 T 23-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS04045 c90298eeb4e6a6f279f65f7c9b302d24 425 SUPERFAMILY SSF55035 113 216 6.41E-34 T 23-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 SPYM18_RS01290 49a33ab1dfd63ec9e2f60c1b1fa133a6 279 Pfam PF02673 Bacitracin resistance protein BacA 9 267 3.4E-75 T 23-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SPYM18_RS01290 49a33ab1dfd63ec9e2f60c1b1fa133a6 279 PANTHER PTHR30622 2 279 2.1E-123 T 23-04-2016 SPYM18_RS01290 49a33ab1dfd63ec9e2f60c1b1fa133a6 279 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 273 16.769 T 23-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 SPYM18_RS01290 49a33ab1dfd63ec9e2f60c1b1fa133a6 279 PANTHER PTHR30622:SF5 2 279 2.1E-123 T 23-04-2016 SPYM18_RS02975 ce433a1acd2187fbfecb4e959104ee0d 145 Gene3D G3DSA:3.40.50.510 1 135 6.6E-38 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02975 ce433a1acd2187fbfecb4e959104ee0d 145 Pfam PF03610 PTS system fructose IIA component 4 113 1.3E-28 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02975 ce433a1acd2187fbfecb4e959104ee0d 145 PANTHER PTHR33799 2 142 4.9E-26 T 23-04-2016 SPYM18_RS02975 ce433a1acd2187fbfecb4e959104ee0d 145 SUPERFAMILY SSF53062 1 130 1.09E-30 T 23-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 SPYM18_RS02975 ce433a1acd2187fbfecb4e959104ee0d 145 PANTHER PTHR33799:SF1 2 142 4.9E-26 T 23-04-2016 SPYM18_RS06595 0736b1f1653cc08fcf6309819a06518a 252 PANTHER PTHR35794 1 236 9.9E-61 T 23-04-2016 SPYM18_RS06595 0736b1f1653cc08fcf6309819a06518a 252 PANTHER PTHR35794:SF2 1 236 9.9E-61 T 23-04-2016 SPYM18_RS06595 0736b1f1653cc08fcf6309819a06518a 252 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 3.2E-13 T 23-04-2016 IPR019933 DivIVA domain SPYM18_RS06595 0736b1f1653cc08fcf6309819a06518a 252 Pfam PF05103 DivIVA protein 3 143 6.0E-43 T 23-04-2016 IPR007793 DivIVA family SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 Gene3D G3DSA:3.40.50.150 149 219 6.9E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 Gene3D G3DSA:3.40.50.150 256 378 6.9E-27 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 PANTHER PTHR18895 47 223 2.0E-95 T 23-04-2016 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 PANTHER PTHR18895 258 381 2.0E-95 T 23-04-2016 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 Pfam PF02926 THUMP domain 20 158 5.3E-6 T 23-04-2016 IPR004114 THUMP domain GO:0003723 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 Pfam PF01170 Putative RNA methylase family UPF0020 167 371 9.6E-54 T 23-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 PANTHER PTHR18895:SF62 47 223 2.0E-95 T 23-04-2016 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 PANTHER PTHR18895:SF62 258 381 2.0E-95 T 23-04-2016 SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 SUPERFAMILY SSF53335 146 222 1.21E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 SUPERFAMILY SSF53335 259 370 1.21E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07140 e49a474f0e759736b21742d9a3b0b541 384 SMART SM00981 58 159 2.0E-6 T 23-04-2016 IPR004114 THUMP domain GO:0003723 SPYM18_RS03795 20bba6143d111b1ca7b0dc2855b73577 325 PANTHER PTHR10948 4 323 1.1E-80 T 23-04-2016 SPYM18_RS03795 20bba6143d111b1ca7b0dc2855b73577 325 SUPERFAMILY SSF53098 176 314 5.88E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS03795 20bba6143d111b1ca7b0dc2855b73577 325 Pfam PF13936 Helix-turn-helix domain 8 51 1.2E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS03795 20bba6143d111b1ca7b0dc2855b73577 325 Gene3D G3DSA:1.10.10.60 7 46 5.8E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS03795 20bba6143d111b1ca7b0dc2855b73577 325 Gene3D G3DSA:3.30.420.10 179 314 4.0E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06815 e8d49cc75ece15da768fa5ea04222e6b 59 SUPERFAMILY SSF55729 1 50 8.29E-9 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS06815 e8d49cc75ece15da768fa5ea04222e6b 59 Gene3D G3DSA:3.40.630.30 1 58 7.0E-13 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS01605 11a0b05fb10c0069b32ff1f0b72b47fe 270 PANTHER PTHR30050 75 255 2.3E-13 T 23-04-2016 SPYM18_RS01605 11a0b05fb10c0069b32ff1f0b72b47fe 270 Pfam PF01695 IstB-like ATP binding protein 87 250 1.0E-13 T 23-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 SPYM18_RS01605 11a0b05fb10c0069b32ff1f0b72b47fe 270 SUPERFAMILY SSF52540 87 228 1.91E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01605 11a0b05fb10c0069b32ff1f0b72b47fe 270 Gene3D G3DSA:3.40.50.300 73 238 1.5E-20 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01605 11a0b05fb10c0069b32ff1f0b72b47fe 270 PANTHER PTHR30050:SF7 75 255 2.3E-13 T 23-04-2016 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 PANTHER PTHR30352 5 249 5.0E-119 T 23-04-2016 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 Gene3D G3DSA:3.80.30.10 77 254 1.3E-65 T 23-04-2016 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 13 250 1.8E-96 T 23-04-2016 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 Pfam PF13353 4Fe-4S single cluster domain 22 148 5.1E-16 T 23-04-2016 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 SUPERFAMILY SSF102114 29 231 7.98E-25 T 23-04-2016 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 ProSitePatterns PS01087 Radical activating enzymes signature. 24 45 - T 23-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 Pfam PF04055 Radical SAM superfamily 30 189 1.8E-30 T 23-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 SPYM18_RS01960 694bcd2d80c21797a803dc9e9e7b06dd 263 PANTHER PTHR30352:SF9 5 249 5.0E-119 T 23-04-2016 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 Pfam PF00156 Phosphoribosyl transferase domain 34 157 7.2E-10 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 40.678 T 23-04-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 PANTHER PTHR11776 1 188 3.5E-81 T 23-04-2016 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 188 1.1E-78 T 23-04-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 Gene3D G3DSA:3.40.50.2020 1 188 2.9E-65 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 PANTHER PTHR11776:SF1 1 188 3.5E-81 T 23-04-2016 SPYM18_RS04730 b79aaaa94981752ddc247ea5a14a2953 193 SUPERFAMILY SSF53271 1 187 1.22E-47 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.2E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.2E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.2E-12 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PANTHER PTHR24322 14 142 3.6E-103 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PANTHER PTHR24322 158 194 3.6E-103 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PANTHER PTHR24322:SF536 14 142 3.6E-103 T 23-04-2016 SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PANTHER PTHR24322:SF536 158 194 3.6E-103 T 23-04-2016 SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 SUPERFAMILY SSF51735 8 258 6.16E-78 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 256 2.6E-63 T 23-04-2016 SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.5E-39 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02980 75e35c89fe2a1164ccc8054d111e7042 264 Gene3D G3DSA:3.40.50.720 2 257 5.3E-82 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS09445 0ac5064a76248703732f550d4da40328 108 SUPERFAMILY SSF46785 2 103 1.65E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09445 0ac5064a76248703732f550d4da40328 108 PANTHER PTHR33169 10 100 3.6E-21 T 23-04-2016 SPYM18_RS09445 0ac5064a76248703732f550d4da40328 108 Pfam PF03551 Transcriptional regulator PadR-like family 14 81 1.7E-19 T 23-04-2016 IPR005149 Transcription regulator PadR, N-terminal SPYM18_RS09445 0ac5064a76248703732f550d4da40328 108 PANTHER PTHR33169:SF3 10 100 3.6E-21 T 23-04-2016 SPYM18_RS09445 0ac5064a76248703732f550d4da40328 108 Gene3D G3DSA:1.10.10.10 8 101 4.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06250 4c95e4ee295532821901caa480344d02 205 Pfam PF07104 Protein of unknown function (DUF1366) 5 96 6.0E-6 T 23-04-2016 IPR009796 Protein of unknown function DUF1366 SPYM18_RS03325 4c95e4ee295532821901caa480344d02 205 Pfam PF07104 Protein of unknown function (DUF1366) 5 96 6.0E-6 T 23-04-2016 IPR009796 Protein of unknown function DUF1366 SPYM18_RS07645 ab7e5467d8367f61e61e2be547de16de 403 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 3 397 2.5E-62 T 23-04-2016 IPR006437 Bacteriophage terminase, large subunit GO:0006323 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 Pfam PF01640 Peptidase C10 family 160 367 1.7E-59 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 SUPERFAMILY SSF54001 32 398 1.08E-111 T 23-04-2016 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 Pfam PF13734 Spi protease inhibitor 33 128 2.8E-19 T 23-04-2016 IPR025896 Spi protease inhibitor SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 288 307 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 185 209 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 321 345 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 353 374 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 375 396 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 PRINTS PR00797 Streptopain (C10) cysteine protease family signature 260 276 2.6E-82 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS09010 364b6301ce86f201847cf9c00418d90b 398 ProDom PD004169 PRECURSOR CYSTEINE STREPTOCOCCAL STREPTOPAIN PROTEINASE PROTEASE THIOL B STREPTOCOCCUS EXOTOXIN 129 398 5.0E-146 T 23-04-2016 IPR000200 Peptidase C10, streptopain GO:0006508|GO:0008234 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 SUPERFAMILY SSF56281 36 314 1.45E-25 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 PANTHER PTHR15032:SF13 4 77 1.1E-128 T 23-04-2016 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 PANTHER PTHR15032:SF13 94 363 1.1E-128 T 23-04-2016 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 Pfam PF13483 Beta-lactamase superfamily domain 42 290 1.5E-14 T 23-04-2016 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 PANTHER PTHR15032 4 77 1.1E-128 T 23-04-2016 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 PANTHER PTHR15032 94 363 1.1E-128 T 23-04-2016 SPYM18_RS00975 95e27644a431a47b1e4d5c76c7c6eddf 363 Gene3D G3DSA:3.60.15.10 1 345 7.2E-120 T 23-04-2016 IPR001279 Metallo-beta-lactamase SPYM18_RS08290 b0f09ed5994241688d8678413a2b33c3 73 Pfam PF01381 Helix-turn-helix 6 63 5.5E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08290 b0f09ed5994241688d8678413a2b33c3 73 Gene3D G3DSA:1.10.260.40 4 65 5.8E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08290 b0f09ed5994241688d8678413a2b33c3 73 SUPERFAMILY SSF47413 5 69 5.07E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08290 b0f09ed5994241688d8678413a2b33c3 73 SMART SM00530 5 63 2.5E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 23-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 PANTHER PTHR11825:SF2 5 338 8.7E-157 T 23-04-2016 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 Gene3D G3DSA:3.20.10.10 162 325 2.2E-58 T 23-04-2016 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 SUPERFAMILY SSF56752 4 336 6.41E-101 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 PIRSF PIRSF006468 2 340 2.3E-118 T 23-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 30 339 3.8E-135 T 23-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 Pfam PF01063 Amino-transferase class IV 55 293 2.4E-35 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 Gene3D G3DSA:3.30.470.10 4 161 2.3E-64 T 23-04-2016 SPYM18_RS04180 6c15e50ce81f181500867fd650894bdc 340 PANTHER PTHR11825 5 338 8.7E-157 T 23-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 SPYM18_RS03495 ffec759202333a825c7067945749db90 166 PANTHER PTHR40044 1 166 4.5E-35 T 23-04-2016 SPYM18_RS03495 ffec759202333a825c7067945749db90 166 PIRSF PIRSF031501 1 166 2.8E-50 T 23-04-2016 IPR010387 Queuosine precursor transporter QueT GO:0005886 SPYM18_RS03495 ffec759202333a825c7067945749db90 166 PANTHER PTHR40044:SF1 1 166 4.5E-35 T 23-04-2016 SPYM18_RS03495 ffec759202333a825c7067945749db90 166 Pfam PF06177 QueT transporter 10 160 2.8E-32 T 23-04-2016 IPR010387 Queuosine precursor transporter QueT GO:0005886 SPYM18_RS02850 0fc7d1996122e1825e6724646b859cfa 207 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 200 2.0E-46 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS02850 0fc7d1996122e1825e6724646b859cfa 207 Gene3D G3DSA:3.40.50.1240 1 206 1.5E-50 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS02850 0fc7d1996122e1825e6724646b859cfa 207 PANTHER PTHR23029 1 206 7.9E-38 T 23-04-2016 SPYM18_RS02850 0fc7d1996122e1825e6724646b859cfa 207 SUPERFAMILY SSF53254 1 206 5.01E-50 T 23-04-2016 IPR029033 Histidine phosphatase superfamily SPYM18_RS02850 0fc7d1996122e1825e6724646b859cfa 207 SMART SM00855 2 160 2.6E-17 T 23-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 PANTHER PTHR24220 5 233 7.1E-105 T 23-04-2016 SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 Gene3D G3DSA:3.40.50.300 2 218 1.3E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 Pfam PF00005 ABC transporter 24 166 2.8E-35 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 SUPERFAMILY SSF52540 4 218 2.13E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 SMART SM00382 32 215 1.8E-14 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS05225 82f195e5b57764c6a5dde550faa6b14a 233 PANTHER PTHR24220:SF577 5 233 7.1E-105 T 23-04-2016 SPYM18_RS07640 3dc399b0fee844d7ff4d3a1d0363c6fd 483 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 11 464 6.3E-86 T 23-04-2016 IPR021145 Portal protein, SPP1 Gp6-like SPYM18_RS07640 3dc399b0fee844d7ff4d3a1d0363c6fd 483 TIGRFAM TIGR01542 A118_put_portal: phage portal protein, putative, A118 family 1 473 1.0E-248 T 23-04-2016 IPR006432 Portal protein, putative, A118-type SPYM18_RS07640 3dc399b0fee844d7ff4d3a1d0363c6fd 483 PIRSF PIRSF011911 1 483 9.9E-256 T 23-04-2016 IPR006432 Portal protein, putative, A118-type SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 215 1.1E-77 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 Pfam PF01895 PhoU domain 121 206 5.8E-17 T 23-04-2016 IPR026022 PhoU domain SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 Pfam PF01895 PhoU domain 18 104 1.7E-24 T 23-04-2016 IPR026022 PhoU domain SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 PIRSF PIRSF003107 1 217 7.5E-66 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 Gene3D G3DSA:1.20.58.220 3 110 3.8E-36 T 23-04-2016 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 Gene3D G3DSA:1.20.58.220 117 216 2.2E-27 T 23-04-2016 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 PANTHER PTHR10010 1 216 9.6E-59 T 23-04-2016 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 PANTHER PTHR10010:SF14 1 216 9.6E-59 T 23-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 SPYM18_RS05145 5e84ef87fc926901f171f4d7d508da22 217 SUPERFAMILY SSF109755 3 216 6.17E-64 T 23-04-2016 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 Gene3D G3DSA:3.40.50.300 7 306 2.1E-98 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 PANTHER PTHR10285:SF7 268 306 1.3E-123 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 PANTHER PTHR10285:SF7 1 252 1.3E-123 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 PANTHER PTHR10285 268 306 1.3E-123 T 23-04-2016 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 PANTHER PTHR10285 1 252 1.3E-123 T 23-04-2016 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 8 306 3.7E-98 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 SUPERFAMILY SSF52540 3 305 6.34E-70 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 Hamap MF_00215 Pantothenate kinase [coaA]. 1 306 147.349 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 86 224 6.0E-13 T 23-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 SPYM18_RS05120 f8d60729c2c189094a806dff75164de4 306 PIRSF PIRSF000545 1 306 7.1E-138 T 23-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PANTHER PTHR11958 4 396 3.0E-191 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 Pfam PF00375 Sodium:dicarboxylate symporter family 13 395 1.9E-64 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 2.1E-13 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PRINTS PR00173 Glutamate-aspartate symporter signature 285 311 2.1E-13 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PRINTS PR00173 Glutamate-aspartate symporter signature 218 237 2.1E-13 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 2.1E-13 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PRINTS PR00173 Glutamate-aspartate symporter signature 320 339 2.1E-13 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 Gene3D G3DSA:1.10.3860.10 6 401 1.7E-84 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 PANTHER PTHR11958:SF68 4 396 3.0E-191 T 23-04-2016 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 402 34.832 T 23-04-2016 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 SPYM18_RS01470 cbf3ad4d93c8094b10f87ff82cecef63 404 SUPERFAMILY SSF118215 13 395 1.57E-94 T 23-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 SPYM18_RS05210 89b6f420a42827d66c9fd1aa6cc20dcb 318 Pfam PF06081 Aromatic acid exporter family member 1 3 141 6.5E-43 T 23-04-2016 IPR010343 Aromatic acid exporter family member 1 SPYM18_RS05210 89b6f420a42827d66c9fd1aa6cc20dcb 318 PANTHER PTHR40064 1 315 4.8E-91 T 23-04-2016 SPYM18_RS05210 89b6f420a42827d66c9fd1aa6cc20dcb 318 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 145 308 8.3E-46 T 23-04-2016 IPR021062 Putative aromatic acid exporter, C-terminal SPYM18_RS05210 89b6f420a42827d66c9fd1aa6cc20dcb 318 PANTHER PTHR40064:SF1 1 315 4.8E-91 T 23-04-2016 SPYM18_RS09250 cdc17412d20316cf97c41e6cce8bb883 243 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 2 241 28.183 T 23-04-2016 IPR005583 Peroxide stress protein YaaA SPYM18_RS09250 cdc17412d20316cf97c41e6cce8bb883 243 Pfam PF03883 Protein of unknown function (DUF328) 3 229 2.2E-49 T 23-04-2016 IPR005583 Peroxide stress protein YaaA SPYM18_RS09250 cdc17412d20316cf97c41e6cce8bb883 243 PANTHER PTHR30283:SF3 4 240 1.1E-43 T 23-04-2016 SPYM18_RS09250 cdc17412d20316cf97c41e6cce8bb883 243 PANTHER PTHR30283 4 240 1.1E-43 T 23-04-2016 SPYM18_RS01500 88098a35bca64b7d57629d21fa73e69d 177 PANTHER PTHR41303:SF1 1 177 1.1E-36 T 23-04-2016 SPYM18_RS01500 88098a35bca64b7d57629d21fa73e69d 177 Pfam PF02620 Uncharacterized ACR, COG1399 54 174 8.5E-22 T 23-04-2016 IPR003772 Protein of unknown function DUF177 SPYM18_RS01500 88098a35bca64b7d57629d21fa73e69d 177 PANTHER PTHR41303 1 177 1.1E-36 T 23-04-2016 SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 PANTHER PTHR10584 219 333 8.5E-51 T 23-04-2016 SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 PANTHER PTHR10584 1 201 8.5E-51 T 23-04-2016 SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 PANTHER PTHR10584:SF203 219 333 8.5E-51 T 23-04-2016 SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 PANTHER PTHR10584:SF203 1 201 8.5E-51 T 23-04-2016 SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 Pfam PF00294 pfkB family carbohydrate kinase 1 312 3.8E-23 T 23-04-2016 IPR011611 Carbohydrate kinase PfkB SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 Gene3D G3DSA:3.40.1190.20 1 328 1.9E-62 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS02990 2aaf266cd2b7ad344c445e15d2ed39d1 333 SUPERFAMILY SSF53613 1 325 8.73E-58 T 23-04-2016 IPR029056 Ribokinase-like SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Pfam PF02986 Fibronectin binding repeat 602 628 4.8E-10 T 23-04-2016 IPR004237 Fibronectin binding repeat SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Pfam PF02986 Fibronectin binding repeat 566 600 2.5E-9 T 23-04-2016 IPR004237 Fibronectin binding repeat SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Pfam PF02986 Fibronectin binding repeat 441 477 8.8E-7 T 23-04-2016 IPR004237 Fibronectin binding repeat SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 657 692 8.7E-4 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 SUPERFAMILY SSF49478 257 357 9.42E-10 T 23-04-2016 SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Pfam PF05738 Cna protein B-type domain 478 540 1.2E-7 T 23-04-2016 IPR008454 Collagen-binding surface protein Cna-like, B-type domain SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Gene3D G3DSA:2.60.40.1140 257 360 4.5E-11 T 23-04-2016 IPR008970 Collagen-binding surface protein Cna, B-type domain SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 145 184 1.7E-15 T 23-04-2016 IPR023849 Uncharacterised domain CHP03934, TQXA SPYM18_RS00780 11f718b54aa8de609afaa031dd8eb126 696 Pfam PF08341 Thioester domain 59 247 6.6E-55 T 23-04-2016 IPR013552 Thioester domain SPYM18_RS04840 7246375bb6cb7aeed1625dab9f1dada8 146 Pfam PF08876 Domain of unknown function (DUF1836) 7 106 3.5E-36 T 23-04-2016 IPR014975 Protein of unknown function DUF1836 SPYM18_RS04840 7246375bb6cb7aeed1625dab9f1dada8 146 Gene3D G3DSA:1.10.1660.10 33 101 9.6E-4 T 23-04-2016 SPYM18_RS04840 7246375bb6cb7aeed1625dab9f1dada8 146 PANTHER PTHR40056 5 138 1.4E-23 T 23-04-2016 SPYM18_RS04840 7246375bb6cb7aeed1625dab9f1dada8 146 PANTHER PTHR40056:SF1 5 138 1.4E-23 T 23-04-2016 SPYM18_RS08825 7abf12e22df70096b4446c64ee02b630 273 Gene3D G3DSA:3.60.10.10 2 270 5.5E-22 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS08825 7abf12e22df70096b4446c64ee02b630 273 SUPERFAMILY SSF56219 3 272 6.54E-31 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS08825 7abf12e22df70096b4446c64ee02b630 273 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 21 262 2.6E-15 T 23-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase SPYM18_RS00945 4d219e1f354184be16e7a6f194b23821 92 SUPERFAMILY SSF52794 1 91 2.22E-19 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS00945 4d219e1f354184be16e7a6f194b23821 92 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 90 1.2E-16 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS00945 4d219e1f354184be16e7a6f194b23821 92 PANTHER PTHR33843 1 92 1.3E-14 T 23-04-2016 SPYM18_RS00945 4d219e1f354184be16e7a6f194b23821 92 Gene3D G3DSA:3.40.50.270 1 92 7.4E-17 T 23-04-2016 SPYM18_RS07435 f82aec8c58548589af060949987401e2 98 PANTHER PTHR34215:SF1 5 94 3.3E-26 T 23-04-2016 SPYM18_RS07435 f82aec8c58548589af060949987401e2 98 Gene3D G3DSA:3.30.1230.10 2 96 1.0E-30 T 23-04-2016 IPR007393 Domain of unknown function DUF448 SPYM18_RS07435 f82aec8c58548589af060949987401e2 98 Pfam PF04296 Protein of unknown function (DUF448) 10 82 4.5E-21 T 23-04-2016 IPR007393 Domain of unknown function DUF448 SPYM18_RS07435 f82aec8c58548589af060949987401e2 98 PANTHER PTHR34215 5 94 3.3E-26 T 23-04-2016 SPYM18_RS07435 f82aec8c58548589af060949987401e2 98 SUPERFAMILY SSF64376 5 95 1.83E-26 T 23-04-2016 IPR007393 Domain of unknown function DUF448 SPYM18_RS01090 dad7217e9bc3bf20faf03f9db10bddc7 255 Pfam PF02677 Uncharacterized BCR, COG1636 39 217 4.1E-65 T 23-04-2016 IPR003828 Protein of unknown function DUF208 SPYM18_RS01090 dad7217e9bc3bf20faf03f9db10bddc7 255 PANTHER PTHR36701 23 255 3.2E-78 T 23-04-2016 SPYM18_RS07905 69410d01e6379b06aadfa96340c49d4b 263 PANTHER PTHR11941 2 260 1.5E-79 T 23-04-2016 SPYM18_RS07905 69410d01e6379b06aadfa96340c49d4b 263 PANTHER PTHR11941:SF76 2 260 1.5E-79 T 23-04-2016 SPYM18_RS07905 69410d01e6379b06aadfa96340c49d4b 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 262 6.8E-42 T 23-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 SPYM18_RS07905 69410d01e6379b06aadfa96340c49d4b 263 SUPERFAMILY SSF52096 1 262 1.89E-65 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS07905 69410d01e6379b06aadfa96340c49d4b 263 Gene3D G3DSA:3.90.226.10 1 261 1.0E-62 T 23-04-2016 IPR029045 ClpP/crotonase-like domain SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 PANTHER PTHR12526 1 428 2.4E-85 T 23-04-2016 SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 Pfam PF13439 Glycosyltransferase Family 4 15 182 1.4E-29 T 23-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 Gene3D G3DSA:3.40.50.2000 190 344 1.2E-24 T 23-04-2016 SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 Pfam PF00534 Glycosyl transferases group 1 196 346 8.7E-28 T 23-04-2016 IPR001296 Glycosyl transferase, family 1 SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 SUPERFAMILY SSF53756 1 374 1.44E-70 T 23-04-2016 SPYM18_RS02490 4a68bb19b5c727a9e4224bbf72b1d946 444 PANTHER PTHR12526:SF363 1 428 2.4E-85 T 23-04-2016 SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 SUPERFAMILY SSF51695 329 556 5.76E-48 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 Pfam PF10110 Membrane domain of glycerophosphoryl diester phosphodiesterase 6 314 1.2E-70 T 23-04-2016 IPR018476 Glycerophosphoryl diester phosphodiesterase, membrane domain SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 333 431 3.7E-20 T 23-04-2016 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 PANTHER PTHR23344:SF23 63 577 3.8E-75 T 23-04-2016 SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 Gene3D G3DSA:3.20.20.190 316 561 3.7E-45 T 23-04-2016 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 SPYM18_RS03870 b6cff77b48175d2ccdca8a142d261f55 577 PANTHER PTHR23344 63 577 3.8E-75 T 23-04-2016 IPR004129 Glycerophosphoryl diester phosphodiesterase GO:0008889 SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 Gene3D G3DSA:3.40.50.300 2 220 1.8E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 PANTHER PTHR24220:SF578 3 218 1.5E-116 T 23-04-2016 SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 SUPERFAMILY SSF52540 1 220 1.91E-74 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 PANTHER PTHR24220 3 218 1.5E-116 T 23-04-2016 SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 Pfam PF00005 ABC transporter 21 169 2.6E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS08975 dd39a6d9f79bc1e1f72455a5e3fa9687 224 SMART SM00382 30 216 5.2E-13 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03585 1df0f18f8321c0941c22b252a7e52a06 128 PIRSF PIRSF032441 2 128 1.2E-53 T 23-04-2016 IPR016996 Uncharacterised conserved protein UCP032441 SPYM18_RS03585 1df0f18f8321c0941c22b252a7e52a06 128 Pfam PF08349 Protein of unknown function (DUF1722) 17 125 2.8E-23 T 23-04-2016 IPR013560 Domain of unknown function DUF1722 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 Gene3D G3DSA:1.10.3720.10 11 223 3.4E-46 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 SUPERFAMILY SSF161098 12 208 1.27E-39 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 PANTHER PTHR30614:SF15 1 228 5.1E-86 T 23-04-2016 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 PANTHER PTHR30614 1 228 5.1E-86 T 23-04-2016 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 223 1.9E-22 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06565 7e6a19e57b6142d640ad6abc0835d398 228 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 117 4.2E-20 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 554 755 6.0E-64 T 23-04-2016 IPR017501 Phage infection protein, YhgE, C-terminal SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 PANTHER PTHR30294 570 755 2.5E-75 T 23-04-2016 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 PANTHER PTHR30294 3 244 2.5E-75 T 23-04-2016 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 Pfam PF12051 Protein of unknown function (DUF3533) 27 179 1.5E-8 T 23-04-2016 IPR022703 Domain of unknown function DUF3533 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 476 501 9.9E-6 T 23-04-2016 IPR023908 xxxLxxG heptad repeat SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 502 529 8.8E-5 T 23-04-2016 IPR023908 xxxLxxG heptad repeat SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 PANTHER PTHR30294:SF25 570 755 2.5E-75 T 23-04-2016 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 PANTHER PTHR30294:SF25 3 244 2.5E-75 T 23-04-2016 SPYM18_RS09460 c4a0f01320c0e4d6d571e470ee372b36 757 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 4 166 1.9E-58 T 23-04-2016 IPR017500 Phage infection protein, YhgE, N-terminal SPYM18_RS02335 dd6f2851c9bb05c7b04b5bf01c627396 444 SUPERFAMILY SSF55874 312 421 6.22E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS02335 dd6f2851c9bb05c7b04b5bf01c627396 444 PANTHER PTHR40448 1 444 8.6E-60 T 23-04-2016 SPYM18_RS02335 dd6f2851c9bb05c7b04b5bf01c627396 444 Pfam PF14501 GHKL domain 342 441 1.3E-11 T 23-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain SPYM18_RS02335 dd6f2851c9bb05c7b04b5bf01c627396 444 Gene3D G3DSA:3.30.565.10 320 421 8.0E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS02335 dd6f2851c9bb05c7b04b5bf01c627396 444 PANTHER PTHR40448:SF1 1 444 8.6E-60 T 23-04-2016 SPYM18_RS02460 bb5797d532364b52076db9a696c3d42b 125 PANTHER PTHR10374 1 125 4.7E-35 T 23-04-2016 SPYM18_RS02460 bb5797d532364b52076db9a696c3d42b 125 Gene3D G3DSA:3.10.180.10 1 121 2.3E-30 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS02460 bb5797d532364b52076db9a696c3d42b 125 SUPERFAMILY SSF54593 2 123 5.1E-29 T 23-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase SPYM18_RS02460 bb5797d532364b52076db9a696c3d42b 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 120 1.4E-14 T 23-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain SPYM18_RS02460 bb5797d532364b52076db9a696c3d42b 125 PANTHER PTHR10374:SF8 1 125 4.7E-35 T 23-04-2016 SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 PANTHER PTHR12358 2 300 1.3E-44 T 23-04-2016 SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 300 1.2E-44 T 23-04-2016 IPR005218 Diacylglycerol/lipid kinase SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 Gene3D G3DSA:3.40.50.10330 2 79 1.8E-5 T 23-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 SMART SM00046 3 133 6.2E-5 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 SUPERFAMILY SSF111331 1 301 1.44E-63 T 23-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain SPYM18_RS04830 dc8de7c1c7c8e75d84dc4504ea527e0f 303 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 128 2.2E-29 T 23-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 SPYM18_RS02220 6993a102716bdb2699586d52f5a4b1d8 285 SUPERFAMILY SSF50249 147 217 1.31E-5 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS02220 6993a102716bdb2699586d52f5a4b1d8 285 Pfam PF13509 S1 domain 8 62 5.0E-7 T 23-04-2016 SPYM18_RS02220 6993a102716bdb2699586d52f5a4b1d8 285 PIRSF PIRSF012524 1 284 1.6E-105 T 23-04-2016 IPR014464 Conserved virulence factor B SPYM18_RS02220 6993a102716bdb2699586d52f5a4b1d8 285 PANTHER PTHR37296 2 285 1.6E-101 T 23-04-2016 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 SUPERFAMILY SSF53167 3 269 1.81E-85 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 266 1.0E-101 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 Pfam PF01048 Phosphorylase superfamily 24 266 6.4E-48 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 PANTHER PTHR11904:SF9 1 269 5.8E-122 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 23-04-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 PANTHER PTHR11904 1 269 5.8E-122 T 23-04-2016 IPR001369 PNP/MTAP phosphorylase SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 PIRSF PIRSF000477 1 269 2.5E-105 T 23-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 266 1.6E-102 T 23-04-2016 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 SPYM18_RS04105 18b29e57ce05d9f0d6376873b4e3043f 269 Gene3D G3DSA:3.40.50.1580 3 269 2.4E-99 T 23-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 SMART SM00382 32 222 3.4E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 Gene3D G3DSA:3.40.50.300 3 235 2.5E-66 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 PANTHER PTHR24220 4 251 1.4E-97 T 23-04-2016 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 PANTHER PTHR24220 267 274 1.4E-97 T 23-04-2016 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 278 5.3E-119 T 23-04-2016 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 PANTHER PTHR24220:SF66 4 251 1.4E-97 T 23-04-2016 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 PANTHER PTHR24220:SF66 267 274 1.4E-97 T 23-04-2016 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 SUPERFAMILY SSF52540 3 237 1.16E-58 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 Pfam PF00005 ABC transporter 24 174 9.1E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS09530 0bbdcee933abf0157e075ceefccbfd2c 280 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 SUPERFAMILY SSF54211 6 193 3.79E-42 T 23-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 Gene3D G3DSA:3.30.230.10 6 193 2.0E-63 T 23-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 Pfam PF00288 GHMP kinases N terminal domain 103 158 1.6E-7 T 23-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 Gene3D G3DSA:3.30.70.890 199 334 6.6E-40 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 SUPERFAMILY SSF55060 198 329 3.6E-31 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 Pfam PF08544 GHMP kinases C terminal 244 320 2.5E-6 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS04035 f64e7c2576d0ee50477fc9faf76c582d 337 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 6 324 1.0E-49 T 23-04-2016 IPR005917 Phosphomevalonate kinase, Gram-positive KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922|UniPathway: UPA00057 SPYM18_RS07600 328100bb13131325e5b98313996e7502 118 Pfam PF11114 Minor capsid protein 2 115 1.2E-40 T 23-04-2016 IPR021080 Minor capsid protein SPYM18_RS05830 020210778ccbd13928d456b6f8c4d286 270 Pfam PF00665 Integrase core domain 107 219 9.6E-21 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS05830 020210778ccbd13928d456b6f8c4d286 270 SUPERFAMILY SSF53098 101 252 1.82E-26 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS05830 020210778ccbd13928d456b6f8c4d286 270 Pfam PF13276 HTH-like domain 28 82 1.5E-22 T 23-04-2016 IPR025948 HTH-like domain SPYM18_RS05830 020210778ccbd13928d456b6f8c4d286 270 PANTHER PTHR32552 1 258 6.4E-64 T 23-04-2016 SPYM18_RS05830 020210778ccbd13928d456b6f8c4d286 270 Gene3D G3DSA:3.30.420.10 101 254 1.7E-20 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 Gene3D G3DSA:3.40.50.2020 5 209 6.1E-87 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 2.3E-90 T 23-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 PANTHER PTHR10285 5 198 6.7E-106 T 23-04-2016 SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 8.8E-78 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 SUPERFAMILY SSF53271 5 207 9.44E-74 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS02005 db535ee259e17d7d1c303a76a1d81cda 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.961 T 23-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 Gene3D G3DSA:3.40.30.10 1 125 1.3E-36 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 SUPERFAMILY SSF52833 1 125 9.09E-39 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 Pfam PF03960 ArsC family 18 113 1.3E-25 T 23-04-2016 IPR006660 Arsenate reductase-like SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 PANTHER PTHR30041 1 134 5.1E-67 T 23-04-2016 SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 35.999 T 23-04-2016 IPR023731 Regulatory protein Spx GO:0045892 SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 2.0E-35 T 23-04-2016 IPR006504 Transcriptional regulator Spx/MgsR SPYM18_RS05190 a6ccaa9ffd7ccc16bfa697e83a0dea3c 134 PANTHER PTHR30041:SF5 1 134 5.1E-67 T 23-04-2016 SPYM18_RS04925 407d262d75828129cd8390a049b2399e 102 PIRSF PIRSF002736 1 97 5.1E-42 T 23-04-2016 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPYM18_RS04925 407d262d75828129cd8390a049b2399e 102 TIGRFAM TIGR01608 citD: citrate lyase acyl carrier protein 1 94 4.0E-34 T 23-04-2016 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPYM18_RS04925 407d262d75828129cd8390a049b2399e 102 Hamap MF_00805 Citrate lyase acyl carrier protein [citD]. 1 97 27.51 T 23-04-2016 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPYM18_RS04925 407d262d75828129cd8390a049b2399e 102 Pfam PF06857 Malonate decarboxylase delta subunit (MdcD) 4 86 3.5E-31 T 23-04-2016 IPR023439 Malonate decarboxylase/citrate lyase acyl carrier protein SPYM18_RS04925 407d262d75828129cd8390a049b2399e 102 ProDom PD015389 LYASE CITRATE ACYL CARRIER GAMMA CHAIN CITD PRECURSOR SIGNAL DIRECT 10 78 4.0E-34 T 23-04-2016 IPR006495 Citrate lyase acyl carrier protein CitD GO:0005737 SPYM18_RS01600 4d3723ac2f202e466579fde811c4db32 253 Pfam PF09524 Conserved phage C-terminus (Phg_2220_C) 162 233 2.3E-26 T 23-04-2016 IPR011741 Phage conserved hypothetical protein, C-terminal SPYM18_RS01600 4d3723ac2f202e466579fde811c4db32 253 Gene3D G3DSA:3.90.640.10 137 224 0.001 T 23-04-2016 SPYM18_RS01600 4d3723ac2f202e466579fde811c4db32 253 TIGRFAM TIGR02220 phg_TIGR02220: phage conserved hypothetical protein, C-terminal domain 159 234 1.9E-37 T 23-04-2016 IPR011741 Phage conserved hypothetical protein, C-terminal SPYM18_RS01600 4d3723ac2f202e466579fde811c4db32 253 Pfam PF06970 Replication initiator protein A (RepA) N-terminus 12 86 5.5E-25 T 23-04-2016 IPR010724 Replication initiator A, N-terminal SPYM18_RS00015 ea229ca9265e3c17028143f1671617f8 65 PIRSF PIRSF037263 1 65 4.7E-32 T 23-04-2016 IPR009296 Protein of unknown function DUF951 SPYM18_RS00015 ea229ca9265e3c17028143f1671617f8 65 PANTHER PTHR38455:SF1 1 63 7.8E-26 T 23-04-2016 SPYM18_RS00015 ea229ca9265e3c17028143f1671617f8 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 63 1.7E-27 T 23-04-2016 IPR009296 Protein of unknown function DUF951 SPYM18_RS00015 ea229ca9265e3c17028143f1671617f8 65 PANTHER PTHR38455 1 63 7.8E-26 T 23-04-2016 SPYM18_RS06385 e4fa4e5bff1418fb79edd7f97293634e 139 Pfam PF07374 Protein of unknown function (DUF1492) 32 131 6.9E-49 T 23-04-2016 IPR010861 Protein of unknown function DUF1492 SPYM18_RS09190 bd6cd2134a0da20066c0630ffffc5b8b 447 Pfam PF13520 Amino acid permease 16 430 8.4E-48 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS09190 bd6cd2134a0da20066c0630ffffc5b8b 447 PIRSF PIRSF006060 1 441 3.3E-65 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS09190 bd6cd2134a0da20066c0630ffffc5b8b 447 PANTHER PTHR11785 15 436 2.4E-74 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS01240 079c068b322cd5b5d4f0d3a4da0fec64 106 Pfam PF13936 Helix-turn-helix domain 8 51 1.6E-17 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS01240 079c068b322cd5b5d4f0d3a4da0fec64 106 Gene3D G3DSA:1.10.10.60 7 46 7.8E-9 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01240 079c068b322cd5b5d4f0d3a4da0fec64 106 SUPERFAMILY SSF46689 6 81 3.23E-5 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01240 079c068b322cd5b5d4f0d3a4da0fec64 106 PANTHER PTHR10948 4 101 5.2E-16 T 23-04-2016 SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 252 5.4E-114 T 23-04-2016 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 2.6E-20 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 PANTHER PTHR19288:SF3 3 252 6.3E-87 T 23-04-2016 SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 Gene3D G3DSA:3.40.50.1000 3 80 5.0E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 Gene3D G3DSA:3.40.50.1000 178 252 5.0E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 Pfam PF13242 HAD-hyrolase-like 179 251 1.3E-19 T 23-04-2016 SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 PANTHER PTHR19288 3 252 6.3E-87 T 23-04-2016 SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 SUPERFAMILY SSF56784 2 252 3.55E-71 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 228 8.3E-38 T 23-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA SPYM18_RS04435 a492fac4780996850f117c54d5f1a2bf 254 Gene3D G3DSA:3.40.50.10410 85 177 1.3E-35 T 23-04-2016 IPR023215 Nitrophenylphosphatase-like domain SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 SUPERFAMILY SSF109604 140 280 4.89E-11 T 23-04-2016 SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 Gene3D G3DSA:2.40.50.140 18 89 4.0E-5 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 Pfam PF01966 HD domain 160 278 6.8E-7 T 23-04-2016 IPR006674 HD domain SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 PANTHER PTHR37294:SF1 1 312 4.1E-117 T 23-04-2016 SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 Gene3D G3DSA:1.10.3210.10 158 292 1.9E-5 T 23-04-2016 IPR006674 HD domain SPYM18_RS01235 85e88363aff069fc7b31ec41089c5ea9 312 PANTHER PTHR37294 1 312 4.1E-117 T 23-04-2016 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 Gene3D G3DSA:2.30.30.60 130 172 8.7E-13 T 23-04-2016 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 Pfam PF00924 Mechanosensitive ion channel 72 268 1.0E-43 T 23-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 SUPERFAMILY SSF82689 178 271 7.59E-6 T 23-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 PANTHER PTHR30460 1 273 9.2E-79 T 23-04-2016 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 SUPERFAMILY SSF82861 24 113 3.4E-16 T 23-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 SPYM18_RS08450 27dd57969bab72e4692b27b2dac1832b 281 SUPERFAMILY SSF50182 115 175 3.6E-14 T 23-04-2016 IPR010920 LSM domain SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 SUPERFAMILY SSF51445 2 463 1.06E-163 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 Pfam PF00232 Glycosyl hydrolase family 1 3 466 1.2E-137 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PANTHER PTHR10353:SF35 4 472 3.5E-285 T 23-04-2016 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PANTHER PTHR10353 4 472 3.5E-285 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 Gene3D G3DSA:3.20.20.80 4 467 4.5E-151 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 360 368 - T 23-04-2016 IPR018120 Glycoside hydrolase family 1, active site SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 23-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 431 443 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 406 423 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 360 368 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 294 308 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS02760 4bacb99f9b7cb9df1c9ed6671e8c9cc1 474 PRINTS PR00131 Glycosyl hydrolase family 1 signature 385 396 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 Gene3D G3DSA:3.20.20.70 17 247 1.6E-83 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 PANTHER PTHR21057 15 247 2.6E-105 T 23-04-2016 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 PANTHER PTHR21057:SF7 15 247 2.6E-105 T 23-04-2016 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 SUPERFAMILY SSF51569 17 248 2.2E-81 T 23-04-2016 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 16 246 4.9E-93 T 23-04-2016 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 SPYM18_RS06835 3457d0429cb1d52c7e8e6dbb3d16e91e 250 Pfam PF00793 DAHP synthetase I family 17 249 4.5E-69 T 23-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 SPYM18_RS03660 28e53634b3c1ba903be7aa0e59e48228 267 PANTHER PTHR30413 7 267 2.8E-48 T 23-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 SPYM18_RS03660 28e53634b3c1ba903be7aa0e59e48228 267 PANTHER PTHR30413:SF8 7 267 2.8E-48 T 23-04-2016 SPYM18_RS03660 28e53634b3c1ba903be7aa0e59e48228 267 Pfam PF01061 ABC-2 type transporter 12 220 2.2E-17 T 23-04-2016 IPR013525 ABC-2 type transporter GO:0016020 SPYM18_RS02595 dcca4a13aec516c503058338a3ff82bb 283 Gene3D G3DSA:1.10.260.40 1 69 9.8E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02595 dcca4a13aec516c503058338a3ff82bb 283 PANTHER PTHR37038:SF1 3 283 4.2E-35 T 23-04-2016 SPYM18_RS02595 dcca4a13aec516c503058338a3ff82bb 283 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 64 282 3.8E-60 T 23-04-2016 IPR010057 Transcription activator MutR, C-terminal SPYM18_RS02595 dcca4a13aec516c503058338a3ff82bb 283 SUPERFAMILY SSF47413 4 65 1.07E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS02595 dcca4a13aec516c503058338a3ff82bb 283 PANTHER PTHR37038 3 283 4.2E-35 T 23-04-2016 SPYM18_RS03150 050eb1cbdca10e2a1bcd6a5761da545a 170 Gene3D G3DSA:3.30.420.10 5 153 9.0E-7 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS03150 050eb1cbdca10e2a1bcd6a5761da545a 170 SUPERFAMILY SSF53098 4 158 1.48E-13 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04825 6e8f42b569272adfe13d5dad79c6eee2 144 Gene3D G3DSA:1.20.120.20 34 134 7.7E-4 T 23-04-2016 SPYM18_RS04825 6e8f42b569272adfe13d5dad79c6eee2 144 SUPERFAMILY SSF58113 33 133 8.37E-5 T 23-04-2016 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 SUPERFAMILY SSF51735 111 289 7.9E-35 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 9 291 33.538 T 23-04-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 12 285 3.6E-61 T 23-04-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 Gene3D G3DSA:3.40.50.720 117 288 1.8E-42 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 14 96 3.2E-29 T 23-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 SUPERFAMILY SSF53223 4 110 2.48E-31 T 23-04-2016 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 PANTHER PTHR21089 1 286 6.4E-86 T 23-04-2016 SPYM18_RS06860 9b72074c82a0d5ac5d034468ce843428 292 Gene3D G3DSA:3.40.192.10 6 116 1.8E-39 T 23-04-2016 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 PANTHER PTHR30614 1 213 8.2E-80 T 23-04-2016 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 1.5E-29 T 23-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 Gene3D G3DSA:1.10.3720.10 8 210 3.0E-53 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 PANTHER PTHR30614:SF11 1 213 8.2E-80 T 23-04-2016 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 SUPERFAMILY SSF161098 10 198 7.72E-45 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05300 7794b1cf7b29968f93acfe0bd12d6d9d 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 210 2.2E-26 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06425 a12ab1058fa312cf82ba551ec7de72c9 265 PIRSF PIRSF031475 3 265 2.6E-112 T 23-04-2016 IPR016974 Uncharacterised phage-associated protein SPYM18_RS06425 a12ab1058fa312cf82ba551ec7de72c9 265 Pfam PF12684 PDDEXK-like domain of unknown function (DUF3799) 22 255 1.3E-83 T 23-04-2016 IPR024432 Putative exodeoxyribonuclease 8, PDDEXK-like domain SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 PANTHER PTHR24220:SF530 6 227 3.4E-86 T 23-04-2016 SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 Gene3D G3DSA:3.40.50.300 3 221 1.9E-50 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 SUPERFAMILY SSF52540 4 218 1.05E-47 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 Pfam PF00005 ABC transporter 21 155 2.1E-24 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 PANTHER PTHR24220 6 227 3.4E-86 T 23-04-2016 SPYM18_RS05340 268dd9bca6d6b580da88ec6956c2a080 232 SMART SM00382 29 204 1.4E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS07830 72aca76ea19f230188533aeb7a063983 303 PANTHER PTHR32502:SF5 1 303 1.5E-155 T 23-04-2016 SPYM18_RS07830 72aca76ea19f230188533aeb7a063983 303 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 303 1.6E-114 T 23-04-2016 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 SPYM18_RS07830 72aca76ea19f230188533aeb7a063983 303 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 6 221 3.7E-89 T 23-04-2016 IPR018405 Phosphotransferase system, mannose/fructose/sorbose family IID component, subgroup GO:0009401|GO:0016021 SPYM18_RS07830 72aca76ea19f230188533aeb7a063983 303 PANTHER PTHR32502 1 303 1.5E-155 T 23-04-2016 SPYM18_RS02950 462c8e17625bcbbac587d9705353cb33 635 SUPERFAMILY SSF48230 70 287 2.11E-36 T 23-04-2016 IPR008929 Chondroitin AC/alginate lyase SPYM18_RS02950 462c8e17625bcbbac587d9705353cb33 635 Pfam PF07940 Heparinase II/III-like protein 342 507 8.3E-23 T 23-04-2016 IPR012480 Heparinase II/III-like MetaCyc: PWY-7651 SPYM18_RS02950 462c8e17625bcbbac587d9705353cb33 635 Gene3D G3DSA:1.50.10.110 85 321 2.3E-17 T 23-04-2016 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 SPYM18_RS02950 462c8e17625bcbbac587d9705353cb33 635 Pfam PF16889 Heparinase II/III N-terminus 19 286 7.7E-22 T 23-04-2016 IPR031680 Heparin-sulfate lyase, N-terminal MetaCyc: PWY-7651 SPYM18_RS02950 462c8e17625bcbbac587d9705353cb33 635 PANTHER PTHR39210 19 626 8.6E-58 T 23-04-2016 SPYM18_RS05480 b0ae039b014d11e0fabf20b9ce7ad8d1 359 Gene3D G3DSA:3.90.1690.10 20 323 7.1E-28 T 23-04-2016 SPYM18_RS05480 b0ae039b014d11e0fabf20b9ce7ad8d1 359 Pfam PF03864 Phage major capsid protein E 20 339 1.3E-32 T 23-04-2016 IPR005564 Major capsid protein GpE GO:0019028 SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 SMART SM00490 242 323 4.7E-21 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 PANTHER PTHR24031 18 353 4.8E-101 T 23-04-2016 SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 Gene3D G3DSA:3.40.50.300 199 354 3.8E-38 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 Pfam PF00270 DEAD/DEAH box helicase 22 181 5.4E-38 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 SUPERFAMILY SSF52540 66 337 6.5E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 Gene3D G3DSA:3.40.50.300 4 198 1.8E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 SMART SM00487 17 207 8.0E-41 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS05975 ce7c1c8ab216b20ffb72410c8c7f0cf7 361 Pfam PF00271 Helicase conserved C-terminal domain 228 323 3.9E-20 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS01920 859e630926af688dc23ad650e9b73e3d 344 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS01920 859e630926af688dc23ad650e9b73e3d 344 PANTHER PTHR10948 4 328 9.3E-83 T 23-04-2016 SPYM18_RS01920 859e630926af688dc23ad650e9b73e3d 344 Gene3D G3DSA:3.30.420.10 179 314 4.5E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS01920 859e630926af688dc23ad650e9b73e3d 344 Gene3D G3DSA:1.10.10.60 7 46 6.2E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01920 859e630926af688dc23ad650e9b73e3d 344 SUPERFAMILY SSF53098 176 314 6.83E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS07015 8948ac0d2516ba4e4f317bed83f74ff3 221 PANTHER PTHR11907:SF9 29 221 8.7E-31 T 23-04-2016 SPYM18_RS07015 8948ac0d2516ba4e4f317bed83f74ff3 221 SUPERFAMILY SSF53271 57 218 5.26E-16 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS07015 8948ac0d2516ba4e4f317bed83f74ff3 221 PANTHER PTHR11907 29 221 8.7E-31 T 23-04-2016 SPYM18_RS07015 8948ac0d2516ba4e4f317bed83f74ff3 221 Gene3D G3DSA:3.40.50.2020 45 220 1.0E-13 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS07135 e21b8034b92f55c56cc51c43bc9acf65 489 Hamap MF_01941 Mid-cell-anchored protein Z [mapZ]. 1 489 26.256 T 23-04-2016 IPR030858 Mid-cell-anchored protein Z GO:0016021|GO:0051301 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 PANTHER PTHR33434 1 281 1.7E-104 T 23-04-2016 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 SUPERFAMILY SSF82549 5 282 7.32E-80 T 23-04-2016 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 Pfam PF02645 Uncharacterised protein, DegV family COG1307 7 282 5.7E-89 T 23-04-2016 IPR003797 DegV SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 Gene3D G3DSA:3.40.50.10170 7 155 5.6E-45 T 23-04-2016 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 Gene3D G3DSA:3.30.1180.10 159 282 2.8E-39 T 23-04-2016 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 PANTHER PTHR33434:SF1 1 281 1.7E-104 T 23-04-2016 SPYM18_RS06505 6ca15d5e313bbedab88ead14b25e8777 283 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 8 280 1.4E-85 T 23-04-2016 IPR003797 DegV SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 ProSitePatterns PS00331 Malic enzymes signature. 158 174 - T 23-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PIRSF PIRSF000106 37 388 2.2E-79 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PANTHER PTHR23406 26 388 1.0E-178 T 23-04-2016 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 Pfam PF00390 Malic enzyme, N-terminal domain 19 114 7.3E-24 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PRINTS PR00072 Malic enzyme signature 79 101 3.09E-6 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PRINTS PR00072 Malic enzyme signature 278 294 3.09E-6 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PRINTS PR00072 Malic enzyme signature 158 174 3.09E-6 T 23-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 SMART SM00919 162 386 3.3E-104 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 SUPERFAMILY SSF53223 14 160 4.53E-55 T 23-04-2016 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 PANTHER PTHR23406:SF23 26 388 1.0E-178 T 23-04-2016 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 SUPERFAMILY SSF51735 162 386 4.53E-66 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 Pfam PF03949 Malic enzyme, NAD binding domain 164 368 2.9E-23 T 23-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 Gene3D G3DSA:3.40.50.10380 13 159 5.2E-55 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 SMART SM01274 17 150 1.5E-83 T 23-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 SPYM18_RS04620 b53e729a409433d8315a3a6c765f3f24 388 Gene3D G3DSA:3.40.50.720 160 382 1.0E-69 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS00035 081da48512d634e6c6e97a86be30436a 90 PIRSF PIRSF038881 1 89 1.8E-38 T 23-04-2016 IPR025490 RNA-binding protein, HP1423 type SPYM18_RS00035 081da48512d634e6c6e97a86be30436a 90 SUPERFAMILY SSF55174 1 81 1.7E-20 T 23-04-2016 SPYM18_RS00035 081da48512d634e6c6e97a86be30436a 90 Gene3D G3DSA:3.10.290.10 1 88 4.0E-23 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS00035 081da48512d634e6c6e97a86be30436a 90 SMART SM00363 1 62 1.9E-9 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS00035 081da48512d634e6c6e97a86be30436a 90 Pfam PF01479 S4 domain 1 47 1.3E-10 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS01310 d14a980e2b655b46afd9586236964d02 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 408 4.7E-78 T 23-04-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 SPYM18_RS01310 d14a980e2b655b46afd9586236964d02 420 PANTHER PTHR30508 1 417 1.5E-129 T 23-04-2016 SPYM18_RS01310 d14a980e2b655b46afd9586236964d02 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 167 392 3.4E-56 T 23-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 SPYM18_RS01310 d14a980e2b655b46afd9586236964d02 420 PANTHER PTHR30508:SF0 1 417 1.5E-129 T 23-04-2016 SPYM18_RS01310 d14a980e2b655b46afd9586236964d02 420 SUPERFAMILY SSF101960 6 417 7.06E-113 T 23-04-2016 SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 340 45.495 T 23-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 60 162 3.3E-17 T 23-04-2016 IPR016188 PurM-like, N-terminal domain SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 Gene3D G3DSA:3.90.650.10 170 339 5.0E-61 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 339 7.1E-37 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 PANTHER PTHR10520 1 330 7.0E-191 T 23-04-2016 SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 Gene3D G3DSA:3.30.1330.10 20 169 2.8E-62 T 23-04-2016 IPR016188 PurM-like, N-terminal domain SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 SUPERFAMILY SSF56042 170 338 2.54E-53 T 23-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 SUPERFAMILY SSF55326 6 169 4.78E-48 T 23-04-2016 SPYM18_RS00280 0b36e23d340ab8e9fa05664072100395 340 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 6 331 1.4E-134 T 23-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 SPYM18_RS00760 aa12e9f72923c232785d829663946673 344 TIGRFAM TIGR03065 srtB_sig_QVPTGV: sortase B signal domain, QVPTGV class 312 343 6.5E-21 T 23-04-2016 IPR017503 Sortase B signal domain, QVPTGV class SPYM18_RS00760 aa12e9f72923c232785d829663946673 344 Pfam PF12892 T surface-antigen of pili 124 209 1.5E-18 T 23-04-2016 IPR022464 Streptococcal pilin isopeptide linker SPYM18_RS00760 aa12e9f72923c232785d829663946673 344 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 113 183 2.7E-23 T 23-04-2016 IPR022464 Streptococcal pilin isopeptide linker SPYM18_RS09435 4a40cb2e67f9e15d6fd7bdb93fd5f616 280 PANTHER PTHR37308 1 278 7.8E-68 T 23-04-2016 SPYM18_RS09435 4a40cb2e67f9e15d6fd7bdb93fd5f616 280 Pfam PF04018 Domain of unknown function (DUF368) 19 236 7.6E-32 T 23-04-2016 IPR007163 Protein of unknown function DUF368 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 Gene3D G3DSA:3.20.110.10 4 286 4.5E-40 T 23-04-2016 IPR027291 Glycoside hydrolase 38/57, N-terminal domain SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 SUPERFAMILY SSF88688 298 392 4.9E-15 T 23-04-2016 IPR028995 Glycoside hydrolase families 57/38, central domain SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 SUPERFAMILY SSF74650 645 879 2.51E-63 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 SUPERFAMILY SSF74650 399 610 2.51E-63 T 23-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 Pfam PF07748 Glycosyl hydrolases family 38 C-terminal domain 403 896 2.4E-23 T 23-04-2016 IPR011682 Glycosyl hydrolase family 38, C-terminal GO:0006013|GO:0015923 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 Pfam PF09261 Alpha mannosidase middle domain 299 369 2.7E-8 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 Pfam PF01074 Glycosyl hydrolases family 38 N-terminal domain 5 270 8.1E-24 T 23-04-2016 IPR000602 Glycoside hydrolase family 38, N-terminal domain GO:0004559|GO:0005975 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 Gene3D G3DSA:1.20.1270.50 300 391 1.4E-10 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607:SF26 638 761 4.3E-211 T 23-04-2016 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607:SF26 5 424 4.3E-211 T 23-04-2016 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607:SF26 450 611 4.3E-211 T 23-04-2016 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 SMART SM00872 297 370 6.7E-20 T 23-04-2016 IPR015341 Glycoside hydrolase family 38, central domain GO:0004553|GO:0008270 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 SUPERFAMILY SSF88713 4 282 1.0E-57 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607 638 761 4.3E-211 T 23-04-2016 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607 5 424 4.3E-211 T 23-04-2016 SPYM18_RS06925 27720464e0e788582b75a283578115e2 901 PANTHER PTHR11607 450 611 4.3E-211 T 23-04-2016 SPYM18_RS01870 ff9c72ea273934b5bd6d609edb570364 80 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 62 1.0E-16 T 23-04-2016 IPR005359 Protein with unknown function UPF0154 SPYM18_RS01870 ff9c72ea273934b5bd6d609edb570364 80 Hamap MF_00363 UPF0154 protein . 2 72 20.164 T 23-04-2016 IPR005359 Protein with unknown function UPF0154 SPYM18_RS01870 ff9c72ea273934b5bd6d609edb570364 80 PANTHER PTHR41297 2 80 3.6E-21 T 23-04-2016 SPYM18_RS01870 ff9c72ea273934b5bd6d609edb570364 80 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 68 2.0E-22 T 23-04-2016 IPR005359 Protein with unknown function UPF0154 SPYM18_RS02100 9a487b74e1e35a7960ad39783b94d144 241 Pfam PF03496 ADP-ribosyltransferase exoenzyme 63 192 3.4E-17 T 23-04-2016 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 SPYM18_RS02100 9a487b74e1e35a7960ad39783b94d144 241 SUPERFAMILY SSF56399 45 202 1.89E-37 T 23-04-2016 SPYM18_RS02100 9a487b74e1e35a7960ad39783b94d144 241 PIRSF PIRSF016951 1 240 5.6E-94 T 23-04-2016 IPR016678 Mono-ADP-ribosyltransferase C3/Edin GO:0006471|GO:0016763 KEGG: 00230+2.4.2.-|KEGG: 00514+2.4.2.- SPYM18_RS02100 9a487b74e1e35a7960ad39783b94d144 241 Gene3D G3DSA:3.90.176.10 45 192 4.7E-36 T 23-04-2016 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 PANTHER PTHR33692 2 172 1.8E-54 T 23-04-2016 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 SUPERFAMILY SSF50346 99 168 4.71E-17 T 23-04-2016 IPR011033 PRC-barrel-like SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 Gene3D G3DSA:2.40.30.60 3 89 9.5E-12 T 23-04-2016 IPR002676 RimM protein GO:0006364 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 Gene3D G3DSA:2.30.30.240 99 168 3.0E-22 T 23-04-2016 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 168 22.173 T 23-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 SUPERFAMILY SSF50447 2 89 1.66E-17 T 23-04-2016 IPR009000 Translation protein, beta-barrel domain SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 168 6.7E-47 T 23-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 Pfam PF01782 RimM N-terminal domain 6 89 8.0E-18 T 23-04-2016 IPR002676 RimM protein GO:0006364 SPYM18_RS03905 d9d324cc44a5137667a8052cdd0e97fe 172 Pfam PF05239 PRC-barrel domain 96 167 7.5E-10 T 23-04-2016 IPR027275 PRC-barrel domain SPYM18_RS07975 5a5b8b0a255439f37893621c2c0f0d80 184 PANTHER PTHR11080 3 182 7.7E-39 T 23-04-2016 SPYM18_RS07975 5a5b8b0a255439f37893621c2c0f0d80 184 Gene3D G3DSA:3.40.50.850 2 180 4.4E-46 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPYM18_RS07975 5a5b8b0a255439f37893621c2c0f0d80 184 Pfam PF00857 Isochorismatase family 3 176 4.0E-32 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPYM18_RS07975 5a5b8b0a255439f37893621c2c0f0d80 184 SUPERFAMILY SSF52499 2 179 1.05E-47 T 23-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Gene3D G3DSA:3.40.50.720 3 88 2.1E-27 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 SUPERFAMILY SSF51984 3 88 2.16E-20 T 23-04-2016 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 PANTHER PTHR23135 1 425 1.1E-146 T 23-04-2016 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Pfam PF08245 Mur ligase middle domain 107 274 7.7E-21 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 SUPERFAMILY SSF53244 295 432 3.66E-35 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Gene3D G3DSA:3.40.1190.10 91 297 1.5E-57 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 377 6.3E-15 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Gene3D G3DSA:3.90.190.20 298 434 7.6E-41 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 PANTHER PTHR23135:SF5 1 425 1.1E-146 T 23-04-2016 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 5 425 9.7E-120 T 23-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Pfam PF01225 Mur ligase family, catalytic domain 4 102 5.1E-26 T 23-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 SUPERFAMILY SSF53623 89 294 2.88E-54 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS01825 d2c9c1d0342e35ae8bf5254209f574aa 442 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 2 436 35.04 T 23-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 Gene3D G3DSA:1.10.10.10 1 73 4.0E-35 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 SUPERFAMILY SSF46785 2 73 5.03E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 Gene3D G3DSA:3.40.50.2020 83 264 4.1E-54 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 1.0E-29 T 23-04-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 PANTHER PTHR11776:SF9 48 263 1.8E-108 T 23-04-2016 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.2E-27 T 23-04-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 8.6E-121 T 23-04-2016 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 Pfam PF00156 Phosphoribosyl transferase domain 107 264 2.2E-26 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 PANTHER PTHR11776 48 263 1.8E-108 T 23-04-2016 SPYM18_RS01245 4ef5b836f159414d2f99364ea489cfdf 279 SUPERFAMILY SSF53271 94 243 3.02E-35 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS01835 cebe5f3697cc9ed6a3cec2c0f3545de4 522 Gene3D G3DSA:3.30.160.60 487 519 1.9E-8 T 23-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 SPYM18_RS01835 cebe5f3697cc9ed6a3cec2c0f3545de4 522 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 159 520 1.4E-75 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like SPYM18_RS01835 cebe5f3697cc9ed6a3cec2c0f3545de4 522 PANTHER PTHR30518:SF2 142 522 1.0E-75 T 23-04-2016 SPYM18_RS01835 cebe5f3697cc9ed6a3cec2c0f3545de4 522 Pfam PF02618 YceG-like family 196 515 4.1E-76 T 23-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like SPYM18_RS01835 cebe5f3697cc9ed6a3cec2c0f3545de4 522 PANTHER PTHR30518 142 522 1.0E-75 T 23-04-2016 SPYM18_RS07180 91cd60a686fe3db07ab1afa8930d2087 459 ProSitePatterns PS00218 Amino acid permeases signature. 49 79 - T 23-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 SPYM18_RS07180 91cd60a686fe3db07ab1afa8930d2087 459 Pfam PF00324 Amino acid permease 24 445 2.3E-81 T 23-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 SPYM18_RS07180 91cd60a686fe3db07ab1afa8930d2087 459 PIRSF PIRSF006060 3 459 5.5E-52 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS07180 91cd60a686fe3db07ab1afa8930d2087 459 PANTHER PTHR11785 5 459 4.9E-124 T 23-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 SPYM18_RS07180 91cd60a686fe3db07ab1afa8930d2087 459 PANTHER PTHR11785:SF29 5 459 4.9E-124 T 23-04-2016 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 Pfam PF06971 Putative DNA-binding protein N-terminus 7 54 2.7E-17 T 23-04-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 PANTHER PTHR35786 7 211 5.0E-95 T 23-04-2016 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 PANTHER PTHR35786:SF1 7 211 5.0E-95 T 23-04-2016 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 212 38.764 T 23-04-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 Pfam PF02629 CoA binding domain 83 182 2.3E-23 T 23-04-2016 IPR003781 CoA-binding GO:0048037 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 SUPERFAMILY SSF51735 83 210 1.12E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 Gene3D G3DSA:1.10.10.10 5 76 3.2E-30 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 SMART SM00881 80 183 6.1E-17 T 23-04-2016 IPR003781 CoA-binding GO:0048037 SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 SUPERFAMILY SSF46785 8 79 5.71E-20 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04660 26284c44425864d221c40b2cc163f928 214 Gene3D G3DSA:3.40.50.720 79 212 2.6E-50 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 Gene3D G3DSA:2.40.50.100 87 106 6.2E-4 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 Gene3D G3DSA:2.40.50.100 185 225 6.2E-4 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 SUPERFAMILY SSF111369 150 274 1.09E-5 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 SUPERFAMILY SSF111369 90 123 1.09E-5 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 PANTHER PTHR32347 9 400 2.3E-48 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 PANTHER PTHR32347:SF14 9 400 2.3E-48 T 23-04-2016 SPYM18_RS03855 55e1a9f5787c39240f11a2e91f849603 423 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 88 273 4.9E-14 T 23-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 PANTHER PTHR30349:SF20 79 395 1.2E-23 T 23-04-2016 SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 Gene3D G3DSA:1.10.150.130 71 164 4.9E-8 T 23-04-2016 IPR023109 Integrase/recombinase, N-terminal SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 Gene3D G3DSA:1.10.443.10 183 369 5.8E-23 T 23-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 Pfam PF14657 AP2-like DNA-binding integrase domain 27 61 8.3E-5 T 23-04-2016 IPR028259 AP2-like integrase, N-terminal domain SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 SUPERFAMILY SSF56349 70 369 3.24E-38 T 23-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 PANTHER PTHR30349 79 395 1.2E-23 T 23-04-2016 SPYM18_RS01540 bb6dd15dbf016b628c158984a1fd2369 398 Pfam PF00589 Phage integrase family 192 367 1.8E-16 T 23-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 SPYM18_RS04985 6b825fe5a5248539d640cf942142dbf2 477 SUPERFAMILY SSF51126 201 446 1.73E-9 T 23-04-2016 IPR011050 Pectin lyase fold/virulence factor SPYM18_RS06110 f745f81dfbea14bf741d7cf6d06fa968 82 Gene3D G3DSA:3.40.710.10 18 80 1.3E-11 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS06110 f745f81dfbea14bf741d7cf6d06fa968 82 SUPERFAMILY SSF56601 22 77 7.59E-9 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS01685 ab90667d432438cb2dd58fabdad767c7 101 SMART SM00507 24 81 2.1E-10 T 23-04-2016 IPR003615 HNH nuclease SPYM18_RS01685 ab90667d432438cb2dd58fabdad767c7 101 PANTHER PTHR41286 9 95 1.2E-13 T 23-04-2016 SPYM18_RS01685 ab90667d432438cb2dd58fabdad767c7 101 Pfam PF01844 HNH endonuclease 37 85 2.3E-12 T 23-04-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SPYM18_RS01685 ab90667d432438cb2dd58fabdad767c7 101 PANTHER PTHR41286:SF1 9 95 1.2E-13 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 Gene3D G3DSA:3.40.190.10 142 276 2.5E-17 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 Pfam PF13416 Bacterial extracellular solute-binding protein 51 322 8.0E-36 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PANTHER PTHR30222 11 356 4.8E-110 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PIRSF PIRSF019574 1 356 5.0E-127 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PANTHER PTHR30222:SF5 11 356 4.8E-110 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 SUPERFAMILY SSF53850 36 353 1.13E-89 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 Gene3D G3DSA:3.40.190.10 34 140 6.3E-64 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 Gene3D G3DSA:3.40.190.10 277 321 6.3E-64 T 23-04-2016 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 57 78 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 84 98 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 131 147 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 41 57 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS04600 d2cc4c740367de39d53c2054d4ab2f79 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 100 113 1.8E-63 T 23-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 SPYM18_RS05840 54cca6dbf8c34327b3bc225d83b7ac32 436 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 2 148 7.3E-62 T 23-04-2016 IPR009827 Dicarboxylate carrier MatC N-terminal SPYM18_RS05840 54cca6dbf8c34327b3bc225d83b7ac32 436 PANTHER PTHR10283 4 12 1.6E-78 T 23-04-2016 SPYM18_RS05840 54cca6dbf8c34327b3bc225d83b7ac32 436 PANTHER PTHR10283 40 435 1.6E-78 T 23-04-2016 SPYM18_RS05840 54cca6dbf8c34327b3bc225d83b7ac32 436 PANTHER PTHR10283:SF92 4 12 1.6E-78 T 23-04-2016 SPYM18_RS05840 54cca6dbf8c34327b3bc225d83b7ac32 436 PANTHER PTHR10283:SF92 40 435 1.6E-78 T 23-04-2016 SPYM18_RS07675 08593a355d8ba2a237b7cc471db329e8 146 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 3 135 2.7E-40 T 23-04-2016 IPR006524 Transcription activator, ArpU family SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 SUPERFAMILY SSF55811 1 146 2.71E-28 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 PANTHER PTHR22769:SF35 18 147 4.6E-19 T 23-04-2016 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 ProSitePatterns PS00893 Nudix box signature. 48 69 - T 23-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 Gene3D G3DSA:3.90.79.10 2 147 4.2E-42 T 23-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 Pfam PF00293 NUDIX domain 20 143 1.2E-14 T 23-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 PANTHER PTHR22769 18 147 4.6E-19 T 23-04-2016 SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 PRINTS PR00502 NUDIX hydrolase family signature 43 57 4.2E-5 T 23-04-2016 IPR020476 NUDIX hydrolase SPYM18_RS06580 f2df0d68666313c167930e049fe30c3e 151 PRINTS PR00502 NUDIX hydrolase family signature 57 72 4.2E-5 T 23-04-2016 IPR020476 NUDIX hydrolase SPYM18_RS02180 f754c6c672c76000c30a5b0c07856dd0 284 PANTHER PTHR30477 3 282 2.7E-121 T 23-04-2016 SPYM18_RS02180 f754c6c672c76000c30a5b0c07856dd0 284 PANTHER PTHR30477:SF13 3 282 2.7E-121 T 23-04-2016 SPYM18_RS02180 f754c6c672c76000c30a5b0c07856dd0 284 SUPERFAMILY SSF81345 9 262 1.22E-43 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS02180 f754c6c672c76000c30a5b0c07856dd0 284 Pfam PF00950 ABC 3 transport family 11 266 5.4E-87 T 23-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 SPYM18_RS02180 f754c6c672c76000c30a5b0c07856dd0 284 Gene3D G3DSA:1.10.3470.10 13 262 2.4E-13 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 PANTHER PTHR23513 4 396 6.8E-85 T 23-04-2016 SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 Pfam PF07690 Major Facilitator Superfamily 20 355 1.0E-21 T 23-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 Gene3D G3DSA:1.20.1250.20 217 399 8.7E-8 T 23-04-2016 SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 Gene3D G3DSA:1.20.1250.20 16 191 7.8E-17 T 23-04-2016 SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 SUPERFAMILY SSF103473 9 400 8.63E-39 T 23-04-2016 IPR020846 Major facilitator superfamily domain SPYM18_RS02640 a53a8cb3eec2c00bc47d64d37f21f0c3 402 PANTHER PTHR23513:SF11 4 396 6.8E-85 T 23-04-2016 SPYM18_RS00710 1079eed7f27cc9de7e4727c3e95e42e7 97 Pfam PF15513 Domain of unknown function (DUF4651) 35 95 3.6E-28 T 23-04-2016 IPR028105 Protein of unknown function DUF4651 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PANTHER PTHR30050:SF2 4 451 9.4E-173 T 23-04-2016 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 SMART SM00382 144 277 1.5E-10 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 ProSitePatterns PS01008 DnaA protein signature. 410 429 - T 23-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Pfam PF00308 Bacterial dnaA protein 112 331 5.9E-85 T 23-04-2016 IPR013317 Chromosomal replication initiator protein DnaA SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 209 223 8.1E-49 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 245 272 8.1E-49 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 145 165 8.1E-49 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 410 429 8.1E-49 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 177 191 8.1E-49 T 23-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 451 30.453 T 23-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 450 9.0E-156 T 23-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 SMART SM00760 360 429 2.7E-40 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 SUPERFAMILY SSF52540 111 325 1.78E-42 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Gene3D G3DSA:1.10.8.60 280 347 8.2E-21 T 23-04-2016 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Gene3D G3DSA:3.40.50.300 106 278 4.3E-57 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 PANTHER PTHR30050 4 451 9.4E-173 T 23-04-2016 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Gene3D G3DSA:1.10.1750.10 356 451 1.1E-38 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 SUPERFAMILY SSF48295 358 451 3.92E-34 T 23-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 SPYM18_RS00005 5597435966fd52eb94eb568571fdea33 451 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 361 429 2.4E-30 T 23-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 128 27.653 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 Gene3D G3DSA:3.90.1030.10 2 128 3.3E-49 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 PANTHER PTHR14413:SF5 1 67 2.2E-57 T 23-04-2016 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 PANTHER PTHR14413:SF5 84 128 2.2E-57 T 23-04-2016 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 128 2.4E-48 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 PANTHER PTHR14413 1 67 2.2E-57 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 PANTHER PTHR14413 84 128 2.2E-57 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 SUPERFAMILY SSF64263 2 128 1.23E-43 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00500 4d443745c08205b00f811bad5e7706c3 128 Pfam PF01196 Ribosomal protein L17 16 128 4.0E-40 T 23-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03460 a4b7ec05d1e7f63812145ea3abcfb23c 452 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 69 452 2.2E-110 T 23-04-2016 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component SPYM18_RS03460 a4b7ec05d1e7f63812145ea3abcfb23c 452 PANTHER PTHR37809 67 437 2.2E-24 T 23-04-2016 SPYM18_RS03460 a4b7ec05d1e7f63812145ea3abcfb23c 452 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 69 421 1.8E-53 T 23-04-2016 IPR003776 YcaO-like domain SPYM18_RS03580 02562f9fa1013589fa6f0bf619a9d3ee 125 SUPERFAMILY SSF82784 4 120 2.88E-15 T 23-04-2016 IPR003718 OsmC/Ohr family SPYM18_RS03580 02562f9fa1013589fa6f0bf619a9d3ee 125 Pfam PF02566 OsmC-like protein 30 117 1.1E-10 T 23-04-2016 IPR003718 OsmC/Ohr family SPYM18_RS03580 02562f9fa1013589fa6f0bf619a9d3ee 125 Gene3D G3DSA:3.30.300.20 26 119 4.1E-9 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 Gene3D G3DSA:3.40.50.2300 1 125 2.8E-39 T 23-04-2016 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 SMART SM00448 1 112 1.3E-41 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 PANTHER PTHR26402 1 200 4.4E-65 T 23-04-2016 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-26 T 23-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 SUPERFAMILY SSF46894 121 215 5.95E-15 T 23-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 Gene3D G3DSA:1.10.10.10 126 219 2.4E-16 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 SMART SM00862 144 219 2.0E-7 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 1.3E-14 T 23-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 PANTHER PTHR26402:SF316 1 200 4.4E-65 T 23-04-2016 SPYM18_RS04015 95a1f83797f588ce68f18882c81b6496 222 SUPERFAMILY SSF52172 1 129 3.56E-38 T 23-04-2016 IPR011006 CheY-like superfamily SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 Gene3D G3DSA:1.10.260.40 5 65 4.4E-22 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 PANTHER PTHR10245 1 66 6.8E-32 T 23-04-2016 SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 SUPERFAMILY SSF47413 5 66 5.9E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 Pfam PF01381 Helix-turn-helix 6 60 3.2E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 SMART SM00530 5 60 5.4E-15 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS08630 b7786d1ada6e4c39b1e24965e4e4d3ac 68 PANTHER PTHR10245:SF56 1 66 6.8E-32 T 23-04-2016 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 Gene3D G3DSA:3.30.360.10 128 310 1.2E-65 T 23-04-2016 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 SUPERFAMILY SSF51735 1 134 5.91E-31 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 SUPERFAMILY SSF55347 126 260 1.37E-37 T 23-04-2016 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 3.2E-14 T 23-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 PANTHER PTHR22604 1 297 1.5E-54 T 23-04-2016 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 PANTHER PTHR22604:SF126 1 297 1.5E-54 T 23-04-2016 SPYM18_RS09265 3c79b148ad7a78e5586bb56195cfc8d8 311 Gene3D G3DSA:3.40.50.720 1 127 1.3E-25 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PANTHER PTHR30408 99 498 4.8E-133 T 23-04-2016 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 Pfam PF02384 N-6 DNA Methylase 171 476 1.8E-109 T 23-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 Gene3D G3DSA:3.40.50.150 196 434 4.8E-39 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 298 304 - T 23-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 SUPERFAMILY SSF53335 87 510 1.03E-133 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 SUPERFAMILY SSF53335 8 45 1.03E-133 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PANTHER PTHR30408:SF4 99 498 4.8E-133 T 23-04-2016 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 Pfam PF12161 HsdM N-terminal domain 8 160 4.6E-22 T 23-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 7 482 2.1E-116 T 23-04-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 8.1E-21 T 23-04-2016 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 210 8.1E-21 T 23-04-2016 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 295 307 8.1E-21 T 23-04-2016 SPYM18_RS08525 1144de56b84b5a9e6f0ce67912de7c81 526 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 222 236 8.1E-21 T 23-04-2016 SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 Pfam PF00430 ATP synthase B/B' CF(0) 12 141 2.4E-27 T 23-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 16 161 7.2E-36 T 23-04-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 PANTHER PTHR33445 10 164 1.1E-31 T 23-04-2016 SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 161 11.982 T 23-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 SUPERFAMILY SSF81573 69 126 2.22E-7 T 23-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPYM18_RS03520 fde940811eaf0b58e6a99c1a65664c54 164 Gene3D G3DSA:1.20.5.620 69 125 3.9E-5 T 23-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain SPYM18_RS08430 daedd1f2badb81d506d2dac41cb078e6 308 SUPERFAMILY SSF53474 45 306 3.57E-42 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08430 daedd1f2badb81d506d2dac41cb078e6 308 Gene3D G3DSA:3.40.50.1820 71 305 3.0E-44 T 23-04-2016 IPR029058 Alpha/Beta hydrolase fold SPYM18_RS08430 daedd1f2badb81d506d2dac41cb078e6 308 PANTHER PTHR12277 74 305 1.1E-83 T 23-04-2016 SPYM18_RS08430 daedd1f2badb81d506d2dac41cb078e6 308 PANTHER PTHR12277:SF68 74 305 1.1E-83 T 23-04-2016 SPYM18_RS08430 daedd1f2badb81d506d2dac41cb078e6 308 Pfam PF12146 Serine aminopeptidase, S33 86 197 2.3E-9 T 23-04-2016 IPR022742 Serine aminopeptidase, S33 SPYM18_RS05020 dabd2e046e5abb04c68ee68bfd270083 112 PANTHER PTHR21075 1 111 4.3E-17 T 23-04-2016 SPYM18_RS05020 dabd2e046e5abb04c68ee68bfd270083 112 Pfam PF03477 ATP cone domain 1 92 1.9E-18 T 23-04-2016 IPR005144 ATP-cone domain SPYM18_RS08680 db75e599fa5be4bc742712f7348d468d 250 Pfam PF07179 SseB protein N-terminal domain 137 245 1.1E-4 T 23-04-2016 IPR009839 SseB protein N-terminal domain SPYM18_RS03865 e983de5c2ea59f48a943379912f74e44 406 Pfam PF12704 MacB-like periplasmic core domain 18 235 7.8E-28 T 23-04-2016 IPR025857 MacB-like periplasmic core domain SPYM18_RS03865 e983de5c2ea59f48a943379912f74e44 406 PANTHER PTHR30572 1 406 4.1E-80 T 23-04-2016 SPYM18_RS03865 e983de5c2ea59f48a943379912f74e44 406 Pfam PF02687 FtsX-like permease family 286 399 8.8E-20 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 Gene3D G3DSA:3.30.70.260 142 201 3.6E-21 T 23-04-2016 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 Gene3D G3DSA:3.40.50.1360 3 141 5.1E-57 T 23-04-2016 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 217 1.9E-55 T 23-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 218 2.7E-82 T 23-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 SUPERFAMILY SSF100950 2 145 1.26E-41 T 23-04-2016 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 221 32.069 T 23-04-2016 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 SUPERFAMILY SSF75445 127 203 6.02E-20 T 23-04-2016 SPYM18_RS04090 46b0b6de7a481f2a98a4d40126b55ce4 227 PANTHER PTHR11934 1 227 2.3E-88 T 23-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 Gene3D G3DSA:3.40.190.10 164 336 3.3E-18 T 23-04-2016 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 PANTHER PTHR30061 1 437 4.4E-48 T 23-04-2016 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 SUPERFAMILY SSF53850 20 437 9.83E-61 T 23-04-2016 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 Pfam PF01547 Bacterial extracellular solute-binding protein 61 351 3.3E-27 T 23-04-2016 IPR006059 Solute-binding family 1 GO:0005215|GO:0006810 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 Gene3D G3DSA:3.40.190.10 337 391 1.3E-30 T 23-04-2016 SPYM18_RS01160 ca16af5622c7d5c7828248167288bdd3 439 Gene3D G3DSA:3.40.190.10 41 161 1.3E-30 T 23-04-2016 SPYM18_RS08560 b8e49640c8f9c4814f4598a750dfb7a9 51 Pfam PF04604 Type-A lantibiotic 4 51 6.8E-18 T 23-04-2016 IPR007682 Lantibiotic, type A, Lactobacillales-type GO:0005576|GO:0042742 SPYM18_RS06585 beb0b53377498755fc59b11e737a49cf 100 Pfam PF08860 Domain of unknown function (DUF1827) 1 96 3.9E-36 T 23-04-2016 IPR014959 Protein of unknown function DUF1827 SPYM18_RS06585 beb0b53377498755fc59b11e737a49cf 100 Gene3D G3DSA:3.40.1720.10 1 98 2.2E-42 T 23-04-2016 SPYM18_RS07385 2adda376c12962b014139102d4ec234b 101 SUPERFAMILY SSF52794 1 98 4.97E-12 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS07385 2adda376c12962b014139102d4ec234b 101 Gene3D G3DSA:3.40.50.270 1 80 4.3E-10 T 23-04-2016 SPYM18_RS07385 2adda376c12962b014139102d4ec234b 101 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 3 56 3.7E-7 T 23-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376:SF32 2 541 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376:SF32 1120 1180 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376:SF32 559 1079 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Gene3D G3DSA:2.40.40.20 339 366 7.3E-38 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Gene3D G3DSA:2.40.40.20 407 477 7.3E-38 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 SUPERFAMILY SSF64484 5 1185 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 332 1.3E-86 T 23-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF05000 RNA polymerase Rpb1, domain 4 706 760 7.9E-13 T 23-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376 2 541 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1193 10.25 T 23-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 SMART SM00663 225 504 1.1E-177 T 23-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1184 0.0 T 23-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF04983 RNA polymerase Rpb1, domain 3 479 664 3.3E-35 T 23-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF04998 RNA polymerase Rpb1, domain 5 771 1132 1.5E-62 T 23-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF00623 RNA polymerase Rpb1, domain 2 388 475 2.5E-29 T 23-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Pfam PF00623 RNA polymerase Rpb1, domain 2 334 383 7.6E-9 T 23-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 Gene3D G3DSA:2.40.50.100 973 1029 8.1E-5 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376 1120 1180 0.0 T 23-04-2016 SPYM18_RS00635 2aacc977c898502020cfc76c03c019f1 1213 PANTHER PTHR19376 559 1079 0.0 T 23-04-2016 SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 Pfam PF02390 Putative methyltransferase 38 206 8.1E-47 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 Gene3D G3DSA:3.40.50.150 43 181 1.4E-9 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 211 27.445 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 208 7.1E-55 T 23-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 SUPERFAMILY SSF53335 30 208 7.64E-32 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 PANTHER PTHR23417 1 209 3.0E-64 T 23-04-2016 SPYM18_RS07455 796d4c2f18595ed3770e5237a2cb196f 211 PANTHER PTHR23417:SF14 1 209 3.0E-64 T 23-04-2016 SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 Gene3D G3DSA:3.40.50.720 2 229 1.4E-58 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 Pfam PF04321 RmlD substrate binding domain 2 280 5.7E-104 T 23-04-2016 IPR029903 RmlD-like substrate binding domain SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 PANTHER PTHR10491:SF4 1 280 4.3E-88 T 23-04-2016 SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 279 2.8E-80 T 23-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 SUPERFAMILY SSF51735 2 279 9.06E-84 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS03645 d7b70b97364858a77092359a696bd728 284 PANTHER PTHR10491 1 280 4.3E-88 T 23-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family SPYM18_RS02765 50f181871141e850bdf686e6228c7538 271 PANTHER PTHR40047 1 271 8.2E-73 T 23-04-2016 SPYM18_RS02765 50f181871141e850bdf686e6228c7538 271 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 266 3.3E-50 T 23-04-2016 IPR015402 Protein of unknown function DUF1980 SPYM18_RS02765 50f181871141e850bdf686e6228c7538 271 Pfam PF09323 Domain of unknown function (DUF1980) 1 178 8.8E-62 T 23-04-2016 IPR015402 Protein of unknown function DUF1980 SPYM18_RS04220 6ed2b6665dc3997a7255e703edc97ace 139 Gene3D G3DSA:1.20.1050.10 15 126 1.7E-17 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like SPYM18_RS04220 6ed2b6665dc3997a7255e703edc97ace 139 Pfam PF00043 Glutathione S-transferase, C-terminal domain 39 126 1.1E-6 T 23-04-2016 IPR004046 Glutathione S-transferase, C-terminal SPYM18_RS04220 6ed2b6665dc3997a7255e703edc97ace 139 SUPERFAMILY SSF47616 12 137 3.34E-18 T 23-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like SPYM18_RS04550 0ae4733781f6cdc182bd47d7200a1192 334 Pfam PF13936 Helix-turn-helix domain 8 51 1.3E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS04550 0ae4733781f6cdc182bd47d7200a1192 334 Gene3D G3DSA:3.30.420.10 179 314 4.2E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04550 0ae4733781f6cdc182bd47d7200a1192 334 PANTHER PTHR10948 4 328 1.2E-82 T 23-04-2016 SPYM18_RS04550 0ae4733781f6cdc182bd47d7200a1192 334 SUPERFAMILY SSF53098 176 314 6.26E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04550 0ae4733781f6cdc182bd47d7200a1192 334 Gene3D G3DSA:1.10.10.60 7 46 6.0E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 Pfam PF10502 Signal peptidase, peptidase S26 129 169 1.4E-4 T 23-04-2016 IPR019533 Peptidase S26 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 SUPERFAMILY SSF51306 24 182 1.83E-38 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 83 2.8E-11 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 26 42 2.8E-11 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 2.8E-11 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 Pfam PF00717 Peptidase S24-like 42 93 1.5E-6 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 176 9.3E-41 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 PANTHER PTHR12383 1 183 8.5E-25 T 23-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 Gene3D G3DSA:2.10.109.10 136 182 1.5E-20 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS05315 095e652b807e407309689d89547eb35a 185 Gene3D G3DSA:2.10.109.10 23 81 1.5E-20 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 Pfam PF13091 PLD-like domain 366 491 3.3E-21 T 23-04-2016 IPR025202 Phospholipase D-like domain SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 Pfam PF13091 PLD-like domain 179 314 7.9E-10 T 23-04-2016 IPR025202 Phospholipase D-like domain SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 PANTHER PTHR21248 134 525 1.4E-86 T 23-04-2016 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 61 525 8.6E-90 T 23-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 Gene3D G3DSA:3.30.870.10 362 516 6.2E-31 T 23-04-2016 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 Gene3D G3DSA:3.30.870.10 156 358 3.5E-44 T 23-04-2016 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 SUPERFAMILY SSF56024 133 354 5.76E-42 T 23-04-2016 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 SMART SM00155 261 288 2.3E-6 T 23-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 SMART SM00155 438 465 1.1E-4 T 23-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 SUPERFAMILY SSF56024 317 510 1.35E-35 T 23-04-2016 SPYM18_RS05025 8c1b626cc9c0a6c03d730ead736da0c1 525 PANTHER PTHR21248:SF5 134 525 1.4E-86 T 23-04-2016 SPYM18_RS08920 406ca75ad364aa79d6f579e3130c582e 66 Gene3D G3DSA:1.10.1470.10 1 66 7.2E-17 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS08920 406ca75ad364aa79d6f579e3130c582e 66 SUPERFAMILY SSF69047 1 65 1.09E-11 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS08920 406ca75ad364aa79d6f579e3130c582e 66 Pfam PF05532 CsbD-like 4 55 8.4E-13 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 Gene3D G3DSA:1.10.10.10 9 66 3.5E-22 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 Hamap MF_00173 Arginine repressor [argR]. 1 155 42.952 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PRINTS PR01467 Bacterial arginine repressor signature 21 34 4.7E-13 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PRINTS PR01467 Bacterial arginine repressor signature 37 52 4.7E-13 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PRINTS PR01467 Bacterial arginine repressor signature 91 104 4.7E-13 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PRINTS PR01467 Bacterial arginine repressor signature 121 136 4.7E-13 T 23-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PANTHER PTHR34471 1 156 1.9E-33 T 23-04-2016 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 SUPERFAMILY SSF55252 91 151 1.44E-11 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 Pfam PF01316 Arginine repressor, DNA binding domain 1 69 2.2E-21 T 23-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 PANTHER PTHR34471:SF1 1 156 1.9E-33 T 23-04-2016 SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 SUPERFAMILY SSF46785 1 69 4.15E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 Gene3D G3DSA:3.30.1360.40 95 149 1.5E-8 T 23-04-2016 IPR024946 Arginine repressor C-terminal-like domain SPYM18_RS06520 e0619186c4bb1eebb29801649b056607 156 Pfam PF02863 Arginine repressor, C-terminal domain 96 148 6.4E-6 T 23-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 SPYM18_RS07355 629c115bb82b54f8c18f804022a91a7b 205 Pfam PF03458 UPF0126 domain 95 164 1.2E-18 T 23-04-2016 IPR005115 Uncharacterised domain UPF0126 SPYM18_RS07355 629c115bb82b54f8c18f804022a91a7b 205 Pfam PF03458 UPF0126 domain 8 81 1.7E-18 T 23-04-2016 IPR005115 Uncharacterised domain UPF0126 SPYM18_RS07355 629c115bb82b54f8c18f804022a91a7b 205 PANTHER PTHR30506 1 205 2.7E-67 T 23-04-2016 SPYM18_RS07355 629c115bb82b54f8c18f804022a91a7b 205 PANTHER PTHR30506:SF3 1 205 2.7E-67 T 23-04-2016 SPYM18_RS08730 cb17224bd6e84473cea4b4ad0778a4c2 180 Pfam PF03358 NADPH-dependent FMN reductase 4 142 6.5E-24 T 23-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 SPYM18_RS08730 cb17224bd6e84473cea4b4ad0778a4c2 180 SUPERFAMILY SSF52218 2 176 8.38E-32 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS08730 cb17224bd6e84473cea4b4ad0778a4c2 180 PANTHER PTHR30543:SF6 1 180 2.2E-35 T 23-04-2016 SPYM18_RS08730 cb17224bd6e84473cea4b4ad0778a4c2 180 PANTHER PTHR30543 1 180 2.2E-35 T 23-04-2016 SPYM18_RS08730 cb17224bd6e84473cea4b4ad0778a4c2 180 Gene3D G3DSA:3.40.50.360 1 178 2.5E-35 T 23-04-2016 IPR029039 Flavoprotein-like domain SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 23-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 Gene3D G3DSA:3.20.20.70 1 307 1.4E-72 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 PIRSF PIRSF000164 1 308 4.5E-61 T 23-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 SUPERFAMILY SSF51395 1 307 1.5E-63 T 23-04-2016 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 Pfam PF01180 Dihydroorotate dehydrogenase 5 292 6.7E-74 T 23-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 304 5.1E-48 T 23-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 PANTHER PTHR11938 41 305 4.1E-149 T 23-04-2016 SPYM18_RS06205 115ef0fbec696b0f637fd26bbeaf9301 311 PANTHER PTHR11938:SF106 41 305 4.1E-149 T 23-04-2016 SPYM18_RS07665 baeaa47a50f0786929e29a4670378e93 225 SMART SM00382 45 175 2.4E-5 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS07665 baeaa47a50f0786929e29a4670378e93 225 SUPERFAMILY SSF52540 20 180 1.4E-13 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07665 baeaa47a50f0786929e29a4670378e93 225 Gene3D G3DSA:3.40.50.300 47 187 6.2E-14 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 Gene3D G3DSA:2.170.150.20 3 142 1.7E-57 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 SUPERFAMILY SSF51316 3 141 4.03E-56 T 23-04-2016 IPR011057 Mss4-like SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 PANTHER PTHR10173 5 134 9.3E-48 T 23-04-2016 IPR028427 Peptide methionine sulfoxide reductase GO:0006979|GO:0016671|GO:0030091 SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 3 135 1.4E-58 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 PANTHER PTHR10173:SF18 5 134 9.3E-48 T 23-04-2016 SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 3 127 34.807 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS04455 fd2bcf7b1ae57092684625bdedacec06 145 Pfam PF01641 SelR domain 6 126 1.3E-46 T 23-04-2016 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 SPYM18_RS06895 a3e008a361fbed0148474253b19e707d 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 309 2.5E-12 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06895 a3e008a361fbed0148474253b19e707d 316 Gene3D G3DSA:1.10.3720.10 75 308 3.4E-46 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06895 a3e008a361fbed0148474253b19e707d 316 SUPERFAMILY SSF161098 69 298 6.15E-48 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06895 a3e008a361fbed0148474253b19e707d 316 PANTHER PTHR30193 17 316 2.8E-111 T 23-04-2016 SPYM18_RS06895 a3e008a361fbed0148474253b19e707d 316 PANTHER PTHR30193:SF19 17 316 2.8E-111 T 23-04-2016 SPYM18_RS02690 76cc89a56a1dea04a69892f5f95d6dd8 225 SUPERFAMILY SSF55681 3 223 3.06E-33 T 23-04-2016 SPYM18_RS02690 76cc89a56a1dea04a69892f5f95d6dd8 225 Pfam PF00152 tRNA synthetases class II (D, K and N) 15 220 4.1E-22 T 23-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 SPYM18_RS02690 76cc89a56a1dea04a69892f5f95d6dd8 225 Gene3D G3DSA:3.30.930.10 7 224 8.4E-29 T 23-04-2016 SPYM18_RS04360 053d329b00ee785283c4caae5c8cf716 322 Pfam PF00676 Dehydrogenase E1 component 15 311 9.5E-86 T 23-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 SPYM18_RS04360 053d329b00ee785283c4caae5c8cf716 322 Gene3D G3DSA:3.40.50.970 3 321 1.1E-126 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS04360 053d329b00ee785283c4caae5c8cf716 322 SUPERFAMILY SSF52518 4 322 1.45E-101 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS04360 053d329b00ee785283c4caae5c8cf716 322 PANTHER PTHR11516 1 322 4.8E-136 T 23-04-2016 SPYM18_RS09545 f96168a002b94a80f3e24a01c9c63055 341 Pfam PF13413 Helix-turn-helix domain 10 67 1.5E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09545 f96168a002b94a80f3e24a01c9c63055 341 PANTHER PTHR34475:SF1 1 338 4.7E-14 T 23-04-2016 SPYM18_RS09545 f96168a002b94a80f3e24a01c9c63055 341 Gene3D G3DSA:1.10.260.40 6 83 2.4E-4 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS09545 f96168a002b94a80f3e24a01c9c63055 341 PANTHER PTHR34475 1 338 4.7E-14 T 23-04-2016 SPYM18_RS05360 13cb423800ac58fe75f5bb6ed63ff282 262 SUPERFAMILY SSF54334 152 258 4.19E-24 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS05360 13cb423800ac58fe75f5bb6ed63ff282 262 Gene3D G3DSA:3.10.20.120 142 258 4.6E-24 T 23-04-2016 IPR016091 Superantigen toxin, C-terminal GO:0005576|GO:0009405 SPYM18_RS05360 13cb423800ac58fe75f5bb6ed63ff282 262 Gene3D G3DSA:2.40.50.110 99 141 8.8E-5 T 23-04-2016 SPYM18_RS05360 13cb423800ac58fe75f5bb6ed63ff282 262 Pfam PF02876 Staphylococcal/Streptococcal toxin, beta-grasp domain 157 256 1.6E-11 T 23-04-2016 IPR006123 Staphylococcal/Streptococcal toxin, beta-grasp domain GO:0005576|GO:0009405 SPYM18_RS03445 2a5f630f3e94eb58b64b5d45f3cd595e 53 TIGRFAM TIGR03602 streptolysinS: bacteriocin protoxin, streptolysin S family 1 52 4.5E-29 T 23-04-2016 IPR019891 Bacteriocin, streptolysin S, precursor SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 Gene3D G3DSA:3.60.21.10 4 166 4.9E-44 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 PANTHER PTHR11124 1 160 1.7E-47 T 23-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 149 1.5E-23 T 23-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 PANTHER PTHR11124:SF14 1 160 1.7E-47 T 23-04-2016 SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 SUPERFAMILY SSF56300 4 171 3.8E-46 T 23-04-2016 IPR029052 Metallo-dependent phosphatase-like SPYM18_RS01885 07d6b4fa3ff8b94a2f22094769a89427 173 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 6 152 7.4E-24 T 23-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 SPYM18_RS05090 1877859aaecad299623d2bfa5785269c 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 297 6.6E-39 T 23-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 SPYM18_RS05090 1877859aaecad299623d2bfa5785269c 318 PANTHER PTHR32196:SF40 9 318 6.0E-116 T 23-04-2016 SPYM18_RS05090 1877859aaecad299623d2bfa5785269c 318 PANTHER PTHR32196 9 318 6.0E-116 T 23-04-2016 SPYM18_RS06335 24d263f5285853c1e0226175cc61820a 303 Pfam PF05065 Phage capsid family 14 298 1.8E-6 T 23-04-2016 IPR024455 Phage capsid SPYM18_RS06335 24d263f5285853c1e0226175cc61820a 303 SUPERFAMILY SSF56563 2 300 6.41E-25 T 23-04-2016 SPYM18_RS04615 57fd758762b441ea753dc3d9dfa5c6dc 443 PANTHER PTHR40033 22 443 5.4E-142 T 23-04-2016 SPYM18_RS04615 57fd758762b441ea753dc3d9dfa5c6dc 443 TIGRFAM TIGR00783 ccs: citrate carrier protein, CCS family 22 436 3.1E-170 T 23-04-2016 IPR018025 2-hydroxycarboxylate transporter, Proteobacteria/Firmicutes SPYM18_RS04615 57fd758762b441ea753dc3d9dfa5c6dc 443 Pfam PF03390 2-hydroxycarboxylate transporter family 25 435 5.7E-153 T 23-04-2016 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPYM18_RS04615 57fd758762b441ea753dc3d9dfa5c6dc 443 PIRSF PIRSF005348 4 442 9.5E-165 T 23-04-2016 IPR004679 2-hydroxycarboxylate transporter GO:0008514|GO:0015711|GO:0016021 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 Gene3D G3DSA:3.40.605.10 4 264 1.7E-84 T 23-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 SUPERFAMILY SSF53720 4 473 3.14E-139 T 23-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 PANTHER PTHR11699 4 474 2.6E-284 T 23-04-2016 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 PANTHER PTHR11699:SF160 4 474 2.6E-284 T 23-04-2016 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 Pfam PF00171 Aldehyde dehydrogenase family 17 470 2.0E-146 T 23-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 23-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 SPYM18_RS05985 e2bd77da86d6068ad5bca9d31add3286 475 Gene3D G3DSA:3.40.309.10 265 444 2.0E-61 T 23-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 SPYM18_RS05560 50999208c57a5b77ab8de497c2cf258d 137 SUPERFAMILY SSF159006 1 136 2.62E-32 T 23-04-2016 SPYM18_RS05560 50999208c57a5b77ab8de497c2cf258d 137 Pfam PF09643 YopX protein 4 133 2.3E-26 T 23-04-2016 IPR019096 YopX protein SPYM18_RS05560 50999208c57a5b77ab8de497c2cf258d 137 Gene3D G3DSA:2.30.30.290 63 136 4.3E-20 T 23-04-2016 IPR023385 YopX-like domain, beta barrel type SPYM18_RS05560 50999208c57a5b77ab8de497c2cf258d 137 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 2 134 3.3E-49 T 23-04-2016 IPR010024 Conserved hypothetical protein CHP1671 SPYM18_RS04770 ae057cc081f0e06e0c931630a967ca1d 150 PANTHER PTHR23091 1 142 7.3E-19 T 23-04-2016 SPYM18_RS04770 ae057cc081f0e06e0c931630a967ca1d 150 Pfam PF00583 Acetyltransferase (GNAT) family 52 130 5.8E-14 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS04770 ae057cc081f0e06e0c931630a967ca1d 150 SUPERFAMILY SSF55729 1 139 3.86E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS04770 ae057cc081f0e06e0c931630a967ca1d 150 Gene3D G3DSA:3.40.630.30 1 142 1.9E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.7E-41 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 143 2.9E-36 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 Hamap MF_01556 Galactose-6-phosphate isomerase subunit LacB [lacB]. 1 171 44.063 T 23-04-2016 IPR004784 Galactose-6-phosphate isomerase subunit LacB GO:0005990|GO:0016861|GO:0050044 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 Gene3D G3DSA:3.40.1400.10 1 154 8.7E-52 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 SUPERFAMILY SSF89623 1 151 3.4E-48 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 PANTHER PTHR30345:SF4 1 171 5.1E-107 T 23-04-2016 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 PIRSF PIRSF005384 1 148 3.0E-48 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS08590 330e9a32c2bf228aaebfa0e8fbb02ece 171 PANTHER PTHR30345 1 171 5.1E-107 T 23-04-2016 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26|UniPathway: UPA00702 SPYM18_RS02895 69f066c47872feaefbb3a5b4d46bfa3c 424 PANTHER PTHR30474:SF2 1 411 3.8E-120 T 23-04-2016 SPYM18_RS02895 69f066c47872feaefbb3a5b4d46bfa3c 424 Pfam PF01098 Cell cycle protein 13 394 1.3E-87 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SPYM18_RS02895 69f066c47872feaefbb3a5b4d46bfa3c 424 PANTHER PTHR30474 1 411 3.8E-120 T 23-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 SPYM18_RS03970 bf00f94651530b8e9863ddd2eb8b4e2e 58 Pfam PF00334 Nucleoside diphosphate kinase 1 41 1.1E-5 T 23-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 SPYM18_RS03970 bf00f94651530b8e9863ddd2eb8b4e2e 58 SUPERFAMILY SSF54919 1 51 1.7E-9 T 23-04-2016 SPYM18_RS03970 bf00f94651530b8e9863ddd2eb8b4e2e 58 Gene3D G3DSA:3.30.70.141 1 42 5.8E-8 T 23-04-2016 SPYM18_RS06380 b36dafadf8352fac9c4b38c6165155ab 114 SMART SM00507 18 78 5.7E-11 T 23-04-2016 IPR003615 HNH nuclease SPYM18_RS06380 b36dafadf8352fac9c4b38c6165155ab 114 Pfam PF01844 HNH endonuclease 30 83 5.2E-14 T 23-04-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SPYM18_RS03280 15278374d941cbd8d2301b1972f14686 202 TIGRFAM TIGR01603 maj_tail_phi13: phage major tail protein, phi13 family 3 185 1.1E-62 T 23-04-2016 IPR006490 Phage major tail protein, phi13 family SPYM18_RS03280 15278374d941cbd8d2301b1972f14686 202 Pfam PF04630 Phage tail tube protein 58 184 3.2E-5 T 23-04-2016 IPR006724 Phage tail tube protein 1 SPYM18_RS03300 7b4500b8c6d0d0ace1b485717a77b45b 247 Pfam PF05709 Phage tail protein 26 166 2.4E-6 T 23-04-2016 IPR008841 Siphovirus-type tail component SPYM18_RS03300 7b4500b8c6d0d0ace1b485717a77b45b 247 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 5 125 1.9E-7 T 23-04-2016 IPR006520 Streptococcus phage 7201, Orf34, N-terminal SPYM18_RS08545 541fdf9f05c69cfa8288f73b8552e046 635 PANTHER PTHR30489 1 612 6.8E-19 T 23-04-2016 SPYM18_RS08545 541fdf9f05c69cfa8288f73b8552e046 635 PIRSF PIRSF018968 2 635 4.8E-64 T 23-04-2016 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 SPYM18_RS08545 541fdf9f05c69cfa8288f73b8552e046 635 Pfam PF02687 FtsX-like permease family 61 179 8.9E-10 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS08545 541fdf9f05c69cfa8288f73b8552e046 635 Pfam PF02687 FtsX-like permease family 518 630 7.0E-7 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS03385 75b2e6f8e443fa9805971f44165f8c3e 313 Gene3D G3DSA:3.90.1640.10 16 190 9.1E-31 T 23-04-2016 SPYM18_RS03385 75b2e6f8e443fa9805971f44165f8c3e 313 SUPERFAMILY SSF64182 15 301 5.62E-73 T 23-04-2016 SPYM18_RS03385 75b2e6f8e443fa9805971f44165f8c3e 313 Pfam PF02272 DHHA1 domain 250 310 3.0E-7 T 23-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 SPYM18_RS03385 75b2e6f8e443fa9805971f44165f8c3e 313 Pfam PF01368 DHH family 18 153 3.8E-13 T 23-04-2016 IPR001667 DDH domain SPYM18_RS03465 d09444a1a00f059aa718e77554393ea0 223 Pfam PF02517 CAAX protease self-immunity 123 206 6.6E-10 T 23-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 SPYM18_RS05285 41334103dc74fb29fcb031739ce18433 257 Pfam PF07373 CAMP factor (Cfa) 40 256 2.7E-86 T 23-04-2016 IPR010860 CAMP factor SPYM18_RS03235 506c3c07435dbc533edc73b37676cee0 584 Pfam PF03354 Phage Terminase 88 554 2.8E-94 T 23-04-2016 IPR005021 Phage terminase SPYM18_RS03235 506c3c07435dbc533edc73b37676cee0 584 PANTHER PTHR41287 5 580 2.0E-85 T 23-04-2016 SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 PANTHER PTHR12029 8 244 1.3E-59 T 23-04-2016 SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 SMART SM00967 28 94 1.3E-14 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 Gene3D G3DSA:3.40.1280.10 103 244 1.5E-47 T 23-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 SUPERFAMILY SSF55315 1 92 2.94E-20 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 SUPERFAMILY SSF75217 82 244 4.25E-42 T 23-04-2016 IPR029028 Alpha/beta knot methyltransferases SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 28 91 8.7E-9 T 23-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 Gene3D G3DSA:3.30.1330.30 1 91 7.2E-23 T 23-04-2016 IPR029064 50S ribosomal protein L30e-like SPYM18_RS01855 09435c7cbf26e25f8e059382658ce0b7 245 Pfam PF00588 SpoU rRNA Methylase family 103 241 4.6E-36 T 23-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 SMART SM00382 29 216 4.3E-18 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 Gene3D G3DSA:3.40.50.300 2 222 9.9E-71 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 SUPERFAMILY SSF52540 2 223 2.66E-73 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 PANTHER PTHR24220:SF578 2 228 1.3E-116 T 23-04-2016 SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 Pfam PF00005 ABC transporter 20 168 1.7E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03860 aefc20eab9db49eb58ec87e96f262e19 228 PANTHER PTHR24220 2 228 1.3E-116 T 23-04-2016 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.5E-56 T 23-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 23-04-2016 IPR019972 Ribosomal protein L14P, conserved site SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.16 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 Gene3D G3DSA:2.40.150.20 1 122 4.2E-52 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 SUPERFAMILY SSF50193 1 122 4.97E-50 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.3E-53 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 SMART SM01374 1 122 3.2E-85 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00420 d0baf5324d0e87839140fc0c3431e5a0 122 PANTHER PTHR11761 1 122 3.5E-73 T 23-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 SUPERFAMILY SSF116734 209 395 1.57E-38 T 23-04-2016 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 PANTHER PTHR30408:SF2 4 394 8.8E-15 T 23-04-2016 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 SUPERFAMILY SSF116734 5 203 1.64E-40 T 23-04-2016 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 Pfam PF01420 Type I restriction modification DNA specificity domain 220 383 8.1E-20 T 23-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 Pfam PF01420 Type I restriction modification DNA specificity domain 17 191 1.5E-17 T 23-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 SPYM18_RS08520 e4fbb01156ab5192c85316e1509a87c0 395 PANTHER PTHR30408 4 394 8.8E-15 T 23-04-2016 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 PANTHER PTHR33989:SF4 1 130 1.2E-146 T 23-04-2016 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 PANTHER PTHR33989:SF4 159 457 1.2E-146 T 23-04-2016 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 PIRSF PIRSF006351 1 459 4.5E-124 T 23-04-2016 IPR004796 Phosphotransferase system, cellobiose-type IIC component GO:0008982|GO:0009401|GO:0016021 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 TIGRFAM TIGR00410 lacE: PTS system, lactose/cellobiose family IIC component 9 455 3.7E-111 T 23-04-2016 IPR004501 Phosphotransferase system, EIIC component, type 3 GO:0008982|GO:0009401|GO:0016021 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 Pfam PF02378 Phosphotransferase system, EIIC 25 385 2.7E-54 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 PANTHER PTHR33989 1 130 1.2E-146 T 23-04-2016 SPYM18_RS05775 867a39e6e7f1e7d0ca69c24f257e6e29 459 PANTHER PTHR33989 159 457 1.2E-146 T 23-04-2016 SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 SMART SM00490 315 398 5.9E-9 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 SMART SM00487 91 267 7.4E-12 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 SUPERFAMILY SSF52540 111 408 1.15E-35 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 Gene3D G3DSA:3.40.50.300 92 242 1.8E-18 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 Pfam PF00271 Helicase conserved C-terminal domain 289 396 1.6E-14 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 Pfam PF00270 DEAD/DEAH box helicase 99 244 3.2E-7 T 23-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 SPYM18_RS07020 111310577d281e62c96910aa78b8b5a3 441 Gene3D G3DSA:3.40.50.300 289 427 4.2E-19 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08460 aa3db1e726c7c8c4cc4778c7801057e6 156 Pfam PF07155 ECF-type riboflavin transporter, S component 4 150 8.7E-27 T 23-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPYM18_RS08460 aa3db1e726c7c8c4cc4778c7801057e6 156 PANTHER PTHR37815 1 152 2.9E-12 T 23-04-2016 SPYM18_RS04885 11a6274f5d2ab6406e5cd8ea73a09cd8 376 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 21 369 1.4E-139 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS04885 11a6274f5d2ab6406e5cd8ea73a09cd8 376 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 21 375 1.1E-154 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS04885 11a6274f5d2ab6406e5cd8ea73a09cd8 376 PIRSF PIRSF015658 1 376 5.9E-172 T 23-04-2016 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS04885 11a6274f5d2ab6406e5cd8ea73a09cd8 376 PANTHER PTHR35806 1 376 5.8E-171 T 23-04-2016 SPYM18_RS02860 8e767658fef612cc332572eeac60f0fc 187 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 8 185 3.3E-58 T 23-04-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 SPYM18_RS02860 8e767658fef612cc332572eeac60f0fc 187 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 10 183 7.2E-53 T 23-04-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 SPYM18_RS02860 8e767658fef612cc332572eeac60f0fc 187 PANTHER PTHR41316 2 187 5.6E-34 T 23-04-2016 SPYM18_RS06455 363d46dda9a438ae2a13cb46159b8f1a 89 SUPERFAMILY SSF46785 3 54 3.46E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06455 363d46dda9a438ae2a13cb46159b8f1a 89 Gene3D G3DSA:1.10.10.10 3 52 5.7E-6 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 Pfam PF00156 Phosphoribosyl transferase domain 46 156 1.0E-15 T 23-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 SUPERFAMILY SSF53271 4 207 6.69E-50 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 Gene3D G3DSA:3.40.50.2020 3 208 3.3E-56 T 23-04-2016 IPR029057 Phosphoribosyltransferase-like SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 11 178 1.9E-46 T 23-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 29.572 T 23-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04135 534b6d7fd3757022978802308f661e39 209 PANTHER PTHR19278 3 208 1.7E-64 T 23-04-2016 SPYM18_RS03670 965d70f16b600f9e3ca1ff1bffcf24be 335 PANTHER PTHR22916:SF2 3 111 1.2E-35 T 23-04-2016 SPYM18_RS03670 965d70f16b600f9e3ca1ff1bffcf24be 335 PANTHER PTHR22916 3 111 1.2E-35 T 23-04-2016 SPYM18_RS03670 965d70f16b600f9e3ca1ff1bffcf24be 335 SUPERFAMILY SSF53448 3 229 2.57E-39 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03670 965d70f16b600f9e3ca1ff1bffcf24be 335 Gene3D G3DSA:3.90.550.10 3 242 7.8E-36 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS03670 965d70f16b600f9e3ca1ff1bffcf24be 335 Pfam PF00535 Glycosyl transferase family 2 5 127 4.2E-23 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 Pfam PF01202 Shikimate kinase 9 158 2.8E-39 T 23-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PANTHER PTHR21087 4 160 1.3E-38 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 Gene3D G3DSA:3.40.50.300 4 160 1.1E-39 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PANTHER PTHR21087:SF0 4 160 1.3E-38 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 Hamap MF_00109 Shikimate kinase [aroK]. 1 161 21.744 T 23-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 SUPERFAMILY SSF52540 4 161 1.66E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PRINTS PR01100 Shikimate kinase family signature 92 109 9.74E-15 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PRINTS PR01100 Shikimate kinase family signature 3 18 9.74E-15 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PRINTS PR01100 Shikimate kinase family signature 70 79 9.74E-15 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PRINTS PR01100 Shikimate kinase family signature 51 59 9.74E-15 T 23-04-2016 SPYM18_RS05895 bd261d8fffe67de1cce4b6ffed61b240 163 PRINTS PR01100 Shikimate kinase family signature 23 36 9.74E-15 T 23-04-2016 SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 316 6.1E-149 T 23-04-2016 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 SUPERFAMILY SSF47240 3 316 8.85E-99 T 23-04-2016 IPR009078 Ferritin-like superfamily SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 Gene3D G3DSA:1.10.620.20 5 280 6.6E-86 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 Pfam PF00268 Ribonucleotide reductase, small chain 8 278 1.3E-83 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 PIRSF PIRSF000355 1 314 4.3E-73 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 SPYM18_RS06010 0aa893b6c2580d234462a0dfc50300f6 319 PANTHER PTHR23409 8 318 2.9E-85 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Pfam PF08455 Bacterial SNF2 helicase associated 215 576 6.6E-63 T 23-04-2016 IPR013663 Helicase, SWF/SNF/SWI type, bacterial SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799:SF651 572 1026 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799:SF651 1 82 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799:SF651 426 487 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 SUPERFAMILY SSF52540 783 1029 8.83E-65 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 SMART SM00487 581 762 1.2E-32 T 23-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 SUPERFAMILY SSF52540 567 781 4.67E-52 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 SMART SM00490 891 973 6.1E-21 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799 572 1026 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799 1 82 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 PANTHER PTHR10799 426 487 1.6E-237 T 23-04-2016 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Pfam PF04434 SWIM zinc finger 39 72 1.2E-5 T 23-04-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Gene3D G3DSA:3.40.50.300 857 1008 1.5E-23 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Pfam PF00176 SNF2 family N-terminal domain 601 852 2.6E-41 T 23-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Pfam PF00271 Helicase conserved C-terminal domain 867 973 7.9E-20 T 23-04-2016 IPR001650 Helicase, C-terminal SPYM18_RS01535 274ff6653c1078d1536c2b293a9c8115 1031 Gene3D G3DSA:3.40.50.300 582 748 1.5E-24 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS08270 0a5b493762adfc997fc21d48dda17be7 329 Gene3D G3DSA:3.30.420.10 179 314 4.1E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08270 0a5b493762adfc997fc21d48dda17be7 329 Pfam PF13936 Helix-turn-helix domain 8 51 1.2E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS08270 0a5b493762adfc997fc21d48dda17be7 329 SUPERFAMILY SSF53098 176 314 6.07E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08270 0a5b493762adfc997fc21d48dda17be7 329 Gene3D G3DSA:1.10.10.60 7 46 5.9E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS08270 0a5b493762adfc997fc21d48dda17be7 329 PANTHER PTHR10948 4 328 4.1E-82 T 23-04-2016 SPYM18_RS04265 a367d6ac213450b9f03d81a53d4e9c00 227 Gene3D G3DSA:1.10.10.630 122 198 1.8E-28 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS04265 a367d6ac213450b9f03d81a53d4e9c00 227 SUPERFAMILY SSF158499 127 190 1.83E-18 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS04265 a367d6ac213450b9f03d81a53d4e9c00 227 Pfam PF07261 Replication initiation and membrane attachment 128 199 2.7E-23 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS04265 a367d6ac213450b9f03d81a53d4e9c00 227 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 126 198 1.1E-24 T 23-04-2016 IPR006343 Replication protein, DnaD/DnaB domain SPYM18_RS04265 a367d6ac213450b9f03d81a53d4e9c00 227 PANTHER PTHR41274 1 224 8.3E-56 T 23-04-2016 SPYM18_RS02355 2fdba87f724977b0b4e5eced4b0fbad7 66 TIGRFAM TIGR01847 bacteriocin_sig: bacteriocin-type signal sequence 4 18 0.0011 T 23-04-2016 IPR010133 Bacteriocin-type signal sequence SPYM18_RS02355 2fdba87f724977b0b4e5eced4b0fbad7 66 TIGRFAM TIGR03949 bact_IIb_cerein: class IIb bacteriocin, lactobin A/cerein 7B family 5 33 1.8E-5 T 23-04-2016 IPR023991 Bacteriocin, class IIb, lactobin A/cerein 7B family SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 PANTHER PTHR38445 1 123 1.9E-21 T 23-04-2016 SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.3E-13 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 SUPERFAMILY SSF46785 4 78 9.57E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 SMART SM00345 15 74 1.2E-11 T 23-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 PANTHER PTHR38445:SF2 1 123 1.9E-21 T 23-04-2016 SPYM18_RS05335 75306fe283997830cb3df3dbf941c89b 123 Gene3D G3DSA:1.10.10.10 2 75 2.2E-23 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 PANTHER PTHR34382 8 109 8.1E-33 T 23-04-2016 SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 PIRSF PIRSF000699 3 108 7.0E-36 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 SUPERFAMILY SSF46973 6 101 6.41E-33 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 Gene3D G3DSA:1.20.58.80 7 104 5.7E-36 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 Pfam PF02255 PTS system, Lactose/Cellobiose specific IIA subunit 9 100 1.2E-32 T 23-04-2016 IPR003188 Phosphotransferase system, lactose/cellobiose-specific IIA subunit GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- SPYM18_RS05785 404081f31c8c76b56d2e70418d300800 111 PANTHER PTHR34382:SF2 8 109 8.1E-33 T 23-04-2016 SPYM18_RS08555 5f9695915b2ca1c40b21e21bdcdda995 537 Pfam PF13575 Domain of unknown function (DUF4135) 106 468 5.6E-82 T 23-04-2016 IPR025410 Domain of unknown function DUF4135 SPYM18_RS08555 5f9695915b2ca1c40b21e21bdcdda995 537 PIRSF PIRSF037228 1 537 4.2E-143 T 23-04-2016 IPR017146 Type 2 lantibiotic biosynthesis protein LanM SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 Pfam PF00005 ABC transporter 21 162 2.1E-33 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 SUPERFAMILY SSF52540 4 223 4.82E-67 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 PANTHER PTHR24220 5 296 1.6E-96 T 23-04-2016 SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 SMART SM00382 29 214 4.6E-9 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 Gene3D G3DSA:3.40.50.300 4 229 2.9E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 PANTHER PTHR24220:SF501 5 296 1.6E-96 T 23-04-2016 SPYM18_RS03475 0f0d0838926a4ac1dd9f3325595ab060 307 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03220 b6b5e7c66c87ff302e34f6d27ce58a7c 112 Pfam PF01844 HNH endonuclease 63 103 1.3E-9 T 23-04-2016 IPR002711 HNH endonuclease GO:0003676|GO:0004519 SPYM18_RS03220 b6b5e7c66c87ff302e34f6d27ce58a7c 112 SMART SM00507 51 101 1.9E-8 T 23-04-2016 IPR003615 HNH nuclease SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 PANTHER PTHR24220:SF431 5 218 8.0E-99 T 23-04-2016 SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 SMART SM00382 32 217 2.5E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 PANTHER PTHR24220 5 218 8.0E-99 T 23-04-2016 SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 Pfam PF00005 ABC transporter 23 169 4.1E-31 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 Gene3D G3DSA:3.40.50.300 2 220 2.4E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03595 2bcc41f88d3c8480d3343870fa34e77d 222 SUPERFAMILY SSF52540 3 220 3.17E-60 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS04115 7886c56f2133372fcb87fea265ace35d 262 Pfam PF09659 CRISPR-associated protein (Cas_Csm6) 7 251 1.7E-23 T 23-04-2016 IPR013489 CRISPR-associated protein Csm6 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 14 346 45.668 T 23-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 SUPERFAMILY SSF46589 24 104 4.97E-18 T 23-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 SUPERFAMILY SSF55681 97 346 6.82E-81 T 23-04-2016 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 PANTHER PTHR11538 97 346 5.2E-108 T 23-04-2016 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 26 92 2.3E-21 T 23-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 43 346 2.1E-105 T 23-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 Pfam PF01409 tRNA synthetases class II core domain (F) 97 346 1.7E-107 T 23-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 SPYM18_RS03570 a03e08646d15a99ca1e54496db06467b 347 Gene3D G3DSA:3.30.930.10 24 347 8.1E-130 T 23-04-2016 SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 Gene3D G3DSA:1.10.1520.10 5 133 1.5E-51 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 SUPERFAMILY SSF69065 6 130 4.88E-44 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 PANTHER PTHR34276 6 132 7.9E-51 T 23-04-2016 SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 PIRSF PIRSF005520 1 134 1.1E-49 T 23-04-2016 IPR008226 Mini-ribonuclease 3 family SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 4 130 28.769 T 23-04-2016 IPR008226 Mini-ribonuclease 3 family SPYM18_RS08660 928c4235fbb0a33bb4df9b9e0c6ee8ad 137 Pfam PF00636 Ribonuclease III domain 15 109 2.6E-14 T 23-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 Gene3D G3DSA:1.10.3720.10 59 288 4.5E-41 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 PANTHER PTHR30425:SF0 1 294 3.8E-109 T 23-04-2016 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 SUPERFAMILY SSF161098 16 276 2.62E-36 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 8 287 1.1E-75 T 23-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 PANTHER PTHR30425 1 294 3.8E-109 T 23-04-2016 SPYM18_RS05160 a451186cd0e0f3d70f4b13c50f0e0722 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 292 3.4E-35 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05660 c62bf7e3a6e152fa2d47358726f48d03 66 PANTHER PTHR10245 5 62 6.7E-16 T 23-04-2016 SPYM18_RS05660 c62bf7e3a6e152fa2d47358726f48d03 66 Pfam PF01381 Helix-turn-helix 6 61 2.0E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05660 c62bf7e3a6e152fa2d47358726f48d03 66 SMART SM00530 5 61 4.5E-16 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05660 c62bf7e3a6e152fa2d47358726f48d03 66 Gene3D G3DSA:1.10.260.40 4 63 1.8E-21 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05660 c62bf7e3a6e152fa2d47358726f48d03 66 SUPERFAMILY SSF47413 5 63 1.46E-17 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 SMART SM00937 46 164 2.6E-49 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 Gene3D G3DSA:3.30.160.20 197 275 7.7E-32 T 23-04-2016 IPR014720 Double-stranded RNA-binding domain SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 SUPERFAMILY SSF75620 1 336 6.8E-128 T 23-04-2016 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 335 36.704 T 23-04-2016 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 PANTHER PTHR11075:SF6 1 337 8.9E-147 T 23-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 PANTHER PTHR11075 1 337 8.9E-147 T 23-04-2016 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 Pfam PF00472 RF-1 domain 198 307 1.2E-37 T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 Gene3D G3DSA:1.20.58.410 1 84 2.3E-16 T 23-04-2016 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 2 334 3.2E-143 T 23-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 214 230 - T 23-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 SPYM18_RS03010 f3b7d40356d04f0b5bc217815b0f6a21 337 Pfam PF03462 PCRF domain 1 189 5.2E-58 T 23-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 SPYM18_RS01180 1e0ac72f6d71174c6cb4af4f25159f21 220 Pfam PF04854 Protein of unknown function, DUF624 29 101 3.0E-12 T 23-04-2016 IPR006938 Protein of unknown function DUF624 SPYM18_RS08060 62a6bcd21064c8ffbfb26906d68b8aaa 285 Pfam PF11545 Cell surface heme-binding protein Shp 29 180 1.1E-106 T 23-04-2016 IPR020985 Cell surface protein Shp, haem-binding domain GO:0020037 SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 Pfam PF02779 Transketolase, pyrimidine binding domain 7 181 2.8E-44 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 Pfam PF02780 Transketolase, C-terminal domain 197 320 1.3E-40 T 23-04-2016 IPR033248 Transketolase, C-terminal domain SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 Gene3D G3DSA:3.40.50.970 4 197 2.1E-77 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 PANTHER PTHR11624 1 330 3.6E-163 T 23-04-2016 IPR033247 Transketolase family SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 SMART SM00861 7 182 6.1E-60 T 23-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 SUPERFAMILY SSF52518 4 207 2.85E-62 T 23-04-2016 IPR029061 Thiamin diphosphate-binding fold SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 SUPERFAMILY SSF52922 193 327 4.06E-41 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 PANTHER PTHR11624:SF78 1 330 3.6E-163 T 23-04-2016 SPYM18_RS04365 4eb6ec90841ac8b04dcedaf90842e4b8 332 Gene3D G3DSA:3.40.50.920 198 327 1.8E-45 T 23-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 SPYM18_RS09335 3a9623753da18c49569976e45007f991 68 SUPERFAMILY SSF158622 7 66 9.29E-11 T 23-04-2016 IPR023378 YheA/YmcA-like domain SPYM18_RS09335 3a9623753da18c49569976e45007f991 68 PIRSF PIRSF021287 4 68 5.3E-15 T 23-04-2016 IPR016783 Biofilm formation YmcA SPYM18_RS09335 3a9623753da18c49569976e45007f991 68 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 59 2.6E-5 T 23-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA SPYM18_RS09335 3a9623753da18c49569976e45007f991 68 Gene3D G3DSA:1.20.1500.10 6 67 7.0E-13 T 23-04-2016 IPR023378 YheA/YmcA-like domain SPYM18_RS02450 62be2710f5d1691691eebdac9408788c 227 Pfam PF06149 Protein of unknown function (DUF969) 3 219 2.1E-86 T 23-04-2016 IPR010374 Protein of unknown function DUF969 SPYM18_RS02450 62be2710f5d1691691eebdac9408788c 227 PANTHER PTHR41293:SF1 1 221 2.1E-88 T 23-04-2016 SPYM18_RS02450 62be2710f5d1691691eebdac9408788c 227 PANTHER PTHR41293 1 221 2.1E-88 T 23-04-2016 SPYM18_RS02790 e3adba61fc199dee2db312653eb9c646 90 Pfam PF04024 PspC domain 4 59 1.5E-15 T 23-04-2016 IPR007168 Phage shock protein, PspC, N-terminal SPYM18_RS02790 e3adba61fc199dee2db312653eb9c646 90 PANTHER PTHR33885 2 75 4.1E-14 T 23-04-2016 SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 6 288 41.113 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 SUPERFAMILY SSF52540 8 160 1.86E-12 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 Pfam PF03668 P-loop ATPase protein family 6 289 1.7E-100 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 PIRSF PIRSF005052 6 291 1.4E-105 T 23-04-2016 IPR005337 RapZ-like family GO:0005524 SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 Gene3D G3DSA:3.40.50.300 4 161 1.5E-16 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 PANTHER PTHR30448 1 295 1.8E-145 T 23-04-2016 SPYM18_RS03050 e61530b0e7c506a95ad4f7136cac30d0 296 PANTHER PTHR30448:SF0 1 295 1.8E-145 T 23-04-2016 SPYM18_RS06880 f342b04355d3a4af791e5fee38732533 201 Pfam PF04854 Protein of unknown function, DUF624 14 89 7.5E-16 T 23-04-2016 IPR006938 Protein of unknown function DUF624 SPYM18_RS04545 fc693b6b3ed1ed6e47c28b3b0ed17c41 320 Gene3D G3DSA:3.20.20.370 135 282 1.0E-27 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPYM18_RS04545 fc693b6b3ed1ed6e47c28b3b0ed17c41 320 Pfam PF01522 Polysaccharide deacetylase 158 281 3.6E-30 T 23-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 SPYM18_RS04545 fc693b6b3ed1ed6e47c28b3b0ed17c41 320 PANTHER PTHR34216 98 319 5.6E-50 T 23-04-2016 SPYM18_RS04545 fc693b6b3ed1ed6e47c28b3b0ed17c41 320 SUPERFAMILY SSF88713 120 303 1.25E-37 T 23-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 SPYM18_RS01865 ebf10f79327193b367ffdaa9e1b31d04 229 PANTHER PTHR23291:SF42 8 229 6.4E-70 T 23-04-2016 SPYM18_RS01865 ebf10f79327193b367ffdaa9e1b31d04 229 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 15 225 3.7E-53 T 23-04-2016 SPYM18_RS01865 ebf10f79327193b367ffdaa9e1b31d04 229 PANTHER PTHR23291 8 229 6.4E-70 T 23-04-2016 IPR006214 Bax inhibitor 1-related SPYM18_RS00040 79ea0a9b93a0f3e3af1c313b1ef585b2 123 PANTHER PTHR40027 1 118 1.0E-20 T 23-04-2016 SPYM18_RS00040 79ea0a9b93a0f3e3af1c313b1ef585b2 123 Pfam PF04977 Septum formation initiator 42 118 1.6E-20 T 23-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 SPYM18_RS00040 79ea0a9b93a0f3e3af1c313b1ef585b2 123 PANTHER PTHR40027:SF1 1 118 1.0E-20 T 23-04-2016 SPYM18_RS09075 7e5d351dde8c0012316cbbae417c5764 58 Gene3D G3DSA:1.20.5.1030 2 52 1.9E-11 T 23-04-2016 SPYM18_RS09075 7e5d351dde8c0012316cbbae417c5764 58 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 3 51 1.6E-10 T 23-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 SPYM18_RS09075 7e5d351dde8c0012316cbbae417c5764 58 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 3 50 2.6E-10 T 23-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 SPYM18_RS08050 1a3a040a1bece5b01bf76e29212811a7 340 PANTHER PTHR30472:SF21 22 340 9.3E-109 T 23-04-2016 SPYM18_RS08050 1a3a040a1bece5b01bf76e29212811a7 340 Gene3D G3DSA:1.10.3470.10 18 337 5.4E-87 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS08050 1a3a040a1bece5b01bf76e29212811a7 340 Pfam PF01032 FecCD transport family 31 336 3.6E-81 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS08050 1a3a040a1bece5b01bf76e29212811a7 340 SUPERFAMILY SSF81345 13 336 1.31E-71 T 23-04-2016 IPR029022 ABC transporter, BtuC-like SPYM18_RS08050 1a3a040a1bece5b01bf76e29212811a7 340 PANTHER PTHR30472 22 340 9.3E-109 T 23-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 SPYM18_RS00595 1c638c00e13fe0abbadd595198b66bbb 70 Pfam PF08544 GHMP kinases C terminal 23 65 2.3E-6 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS00595 1c638c00e13fe0abbadd595198b66bbb 70 SUPERFAMILY SSF55060 6 66 2.77E-15 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS00595 1c638c00e13fe0abbadd595198b66bbb 70 Gene3D G3DSA:3.30.70.890 2 66 7.0E-15 T 23-04-2016 IPR013750 GHMP kinase, C-terminal domain SPYM18_RS02625 670a004b6ec8969f1afba96ef1dfef0c 320 Gene3D G3DSA:3.40.50.300 97 155 6.1E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS02625 670a004b6ec8969f1afba96ef1dfef0c 320 SUPERFAMILY SSF53795 98 210 2.5E-7 T 23-04-2016 SPYM18_RS05675 ff78cdcfba5a934a4df85705bb62824d 269 Gene3D G3DSA:2.30.30.110 210 259 9.5E-18 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS05675 ff78cdcfba5a934a4df85705bb62824d 269 Gene3D G3DSA:2.30.30.110 58 123 9.5E-18 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS05675 ff78cdcfba5a934a4df85705bb62824d 269 SUPERFAMILY SSF50118 58 110 1.94E-6 T 23-04-2016 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor SPYM18_RS05675 ff78cdcfba5a934a4df85705bb62824d 269 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 59 124 7.2E-5 T 23-04-2016 IPR003477 mRNA interferase PemK-like protein GO:0003677 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.6E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.6E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.6E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.6E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 PANTHER PTHR33164 31 144 3.6E-20 T 23-04-2016 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 SMART SM00347 26 126 1.6E-22 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 SUPERFAMILY SSF46785 6 142 4.82E-29 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 Gene3D G3DSA:1.10.10.10 2 142 1.6E-37 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS07900 44a2bd3561eebd6428958d7b76b65372 144 Pfam PF01047 MarR family 34 91 2.6E-13 T 23-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 PANTHER PTHR10363 4 444 7.2E-257 T 23-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 Pfam PF03051 Peptidase C1-like family 4 440 3.6E-203 T 23-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 Gene3D G3DSA:3.90.70.10 51 443 6.3E-171 T 23-04-2016 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 361 371 - T 23-04-2016 IPR025660 Cysteine peptidase, histidine active site SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 PANTHER PTHR10363:SF4 4 444 7.2E-257 T 23-04-2016 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 SUPERFAMILY SSF54001 15 443 1.54E-127 T 23-04-2016 SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 63 74 - T 23-04-2016 IPR000169 Cysteine peptidase, cysteine active site SPYM18_RS07165 3cd108df98b52348a030a53edb09a7ac 445 PIRSF PIRSF005700 1 444 1.9E-174 T 23-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 SPYM18_RS01780 b4e9b689141533f3222fe156c13abdb4 142 Pfam PF07761 Protein of unknown function (DUF1617) 1 140 1.1E-76 T 23-04-2016 IPR011675 Protein of unknown function DUF1617 SPYM18_RS05040 92838107ad6ba756da27406389a2257b 293 Gene3D G3DSA:3.40.50.1220 96 176 3.1E-7 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain SPYM18_RS05040 92838107ad6ba756da27406389a2257b 293 Gene3D G3DSA:3.40.50.1220 10 41 3.1E-7 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain SPYM18_RS05040 92838107ad6ba756da27406389a2257b 293 SUPERFAMILY SSF52467 5 264 1.45E-38 T 23-04-2016 IPR029035 DHS-like NAD/FAD-binding domain SPYM18_RS02720 d070777c95e2f3a86bfc9a377fc30638 243 Pfam PF00665 Integrase core domain 83 198 2.9E-32 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS02720 d070777c95e2f3a86bfc9a377fc30638 243 Gene3D G3DSA:3.30.420.10 77 237 3.4E-33 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02720 d070777c95e2f3a86bfc9a377fc30638 243 Pfam PF13276 HTH-like domain 4 52 8.2E-7 T 23-04-2016 IPR025948 HTH-like domain SPYM18_RS02720 d070777c95e2f3a86bfc9a377fc30638 243 PANTHER PTHR32552 38 239 8.7E-29 T 23-04-2016 SPYM18_RS02720 d070777c95e2f3a86bfc9a377fc30638 243 SUPERFAMILY SSF53098 76 238 5.82E-36 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS07255 17cce7fc69977f8e9fed092c003991a9 88 Pfam PF08951 Enterocin A Immunity 5 77 2.3E-16 T 23-04-2016 IPR015046 Enterocin A Immunity SPYM18_RS07255 17cce7fc69977f8e9fed092c003991a9 88 SUPERFAMILY SSF109797 1 86 2.59E-23 T 23-04-2016 SPYM18_RS07255 17cce7fc69977f8e9fed092c003991a9 88 Gene3D G3DSA:1.20.1470.10 1 81 1.5E-19 T 23-04-2016 SPYM18_RS03270 00ddff61f88eefdaafc89abf1fc5a112 125 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 6 90 6.1E-7 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPYM18_RS03270 00ddff61f88eefdaafc89abf1fc5a112 125 TIGRFAM TIGR01725 phge_HK97_gp10: phage protein, HK97 gp10 family 2 123 2.7E-23 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 SUPERFAMILY SSF56978 105 573 1.14E-199 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:3.90.840.10 173 245 1.6E-69 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:3.90.840.10 425 447 1.6E-69 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:3.90.840.10 106 127 1.6E-69 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:3.90.840.10 296 349 1.6E-69 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Pfam PF01289 Thiol-activated cytolysin 111 568 1.5E-205 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:2.60.40.1430 466 572 1.8E-44 T 23-04-2016 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 472 489 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 119 136 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 332 355 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 251 266 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 547 567 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 489 505 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 193 211 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 385 402 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 149 171 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 433 460 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 PRINTS PR01400 Bacterial thiol-activated pore-forming cytolysin signature 177 193 1.6E-113 T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 ProSitePatterns PS00481 Thiol-activated cytolysins signature. 531 542 - T 23-04-2016 IPR001869 Thiol-activated cytolysin GO:0009405|GO:0015485 SPYM18_RS00910 56778da8181017e92ebaa0cc305156d8 574 Gene3D G3DSA:3.30.1040.20 128 172 3.4E-29 T 23-04-2016 SPYM18_RS02970 e6813618ddd69ba11c094e2da27669a1 399 SUPERFAMILY SSF48208 30 399 3.34E-121 T 23-04-2016 IPR008928 Six-hairpin glycosidase-like GO:0003824 SPYM18_RS02970 e6813618ddd69ba11c094e2da27669a1 399 PANTHER PTHR36845 5 399 1.9E-88 T 23-04-2016 SPYM18_RS02970 e6813618ddd69ba11c094e2da27669a1 399 PANTHER PTHR36845:SF1 5 399 1.9E-88 T 23-04-2016 SPYM18_RS02970 e6813618ddd69ba11c094e2da27669a1 399 Pfam PF07470 Glycosyl Hydrolase Family 88 56 393 5.3E-83 T 23-04-2016 IPR010905 Glycosyl hydrolase, family 88 SPYM18_RS02970 e6813618ddd69ba11c094e2da27669a1 399 Gene3D G3DSA:1.50.10.10 30 399 8.8E-141 T 23-04-2016 IPR012341 Six-hairpin glycosidase GO:0003824 SPYM18_RS01650 c8432da310ab83d055e29c885a8d5d90 112 SUPERFAMILY SSF47413 3 64 1.13E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01650 c8432da310ab83d055e29c885a8d5d90 112 SMART SM00530 4 59 1.8E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS01650 c8432da310ab83d055e29c885a8d5d90 112 Gene3D G3DSA:1.10.260.40 4 79 8.4E-18 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01650 c8432da310ab83d055e29c885a8d5d90 112 Pfam PF01381 Helix-turn-helix 5 59 6.9E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05875 b4d608b38b3b3e51f4f962d51dd47765 133 Pfam PF03061 Thioesterase superfamily 43 116 2.8E-19 T 23-04-2016 IPR006683 Thioesterase domain SPYM18_RS05875 b4d608b38b3b3e51f4f962d51dd47765 133 Gene3D G3DSA:3.10.129.10 18 130 1.3E-32 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS05875 b4d608b38b3b3e51f4f962d51dd47765 133 SUPERFAMILY SSF54637 18 130 1.04E-25 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS05875 b4d608b38b3b3e51f4f962d51dd47765 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 124 3.5E-17 T 23-04-2016 IPR003736 Phenylacetic acid degradation-related domain SPYM18_RS05875 b4d608b38b3b3e51f4f962d51dd47765 133 PANTHER PTHR21660 15 126 2.2E-20 T 23-04-2016 SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 Gene3D G3DSA:3.40.50.300 1 208 3.2E-62 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 PANTHER PTHR11059 2 551 2.6E-161 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 PIRSF PIRSF003128 1 553 1.6E-172 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 SUPERFAMILY SSF52540 345 526 7.84E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 SUPERFAMILY SSF52540 288 316 7.84E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 SUPERFAMILY SSF52540 1 201 7.84E-64 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 Gene3D G3DSA:3.40.50.300 374 506 1.2E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 511 4.6E-21 T 23-04-2016 IPR003395 RecF/RecN/SMC, N-terminal SPYM18_RS06515 c18f1bb4bf2c8746e35104bbf9863010 553 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 2.9E-167 T 23-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 SPYM18_RS02965 9fca7a85265eeeeb8743441580fb49df 162 Pfam PF03830 PTS system sorbose subfamily IIB component 6 149 4.6E-41 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS02965 9fca7a85265eeeeb8743441580fb49df 162 SUPERFAMILY SSF52728 5 159 1.31E-43 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS02965 9fca7a85265eeeeb8743441580fb49df 162 PANTHER PTHR33799 1 135 1.3E-47 T 23-04-2016 SPYM18_RS02965 9fca7a85265eeeeb8743441580fb49df 162 PANTHER PTHR33799:SF6 1 135 1.3E-47 T 23-04-2016 SPYM18_RS02965 9fca7a85265eeeeb8743441580fb49df 162 Gene3D G3DSA:3.40.35.10 5 154 4.9E-46 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS09185 8f2970f9ccecf72d3b8e14ee426b6cac 198 SUPERFAMILY SSF51182 4 174 6.67E-26 T 23-04-2016 IPR011051 RmlC-like cupin domain SPYM18_RS09185 8f2970f9ccecf72d3b8e14ee426b6cac 198 Pfam PF05962 HutD 10 170 4.5E-20 T 23-04-2016 IPR010282 Uncharacterised protein family HutD/Ves SPYM18_RS09185 8f2970f9ccecf72d3b8e14ee426b6cac 198 Gene3D G3DSA:2.60.120.10 10 114 4.3E-15 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 444 3.9E-126 T 23-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 SUPERFAMILY SSF51984 10 100 5.23E-17 T 23-04-2016 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 PANTHER PTHR23135 1 451 1.2E-159 T 23-04-2016 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Gene3D G3DSA:3.90.190.20 311 442 4.8E-41 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 380 2.9E-11 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Gene3D G3DSA:3.40.1190.10 102 309 8.4E-57 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Gene3D G3DSA:3.40.50.720 6 99 9.7E-19 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 SUPERFAMILY SSF53623 103 307 2.62E-53 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 SUPERFAMILY SSF53244 309 445 2.38E-36 T 23-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 35.06 T 23-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 Pfam PF08245 Mur ligase middle domain 117 290 5.3E-34 T 23-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 SPYM18_RS06640 96295c1403bbdea9b73802023ea52ad2 452 PANTHER PTHR23135:SF2 1 451 1.2E-159 T 23-04-2016 SPYM18_RS02725 ff32c57d9a1facf2aa3522b598a06e14 91 PANTHER PTHR33215 1 87 2.1E-14 T 23-04-2016 SPYM18_RS02725 ff32c57d9a1facf2aa3522b598a06e14 91 Pfam PF01527 Transposase 5 76 4.2E-16 T 23-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 SPYM18_RS02725 ff32c57d9a1facf2aa3522b598a06e14 91 SUPERFAMILY SSF46689 5 89 5.55E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS02725 ff32c57d9a1facf2aa3522b598a06e14 91 Gene3D G3DSA:1.10.10.60 9 83 2.6E-20 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS06260 5404ffeac798d7464978e871dedd34d5 594 Pfam PF07902 gp58-like protein 1 580 1.2E-201 T 23-04-2016 IPR012892 Gp58-like SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 Gene3D G3DSA:3.40.50.620 4 169 6.8E-16 T 23-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 PANTHER PTHR11807 5 409 8.8E-68 T 23-04-2016 SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 SUPERFAMILY SSF52402 11 211 3.97E-51 T 23-04-2016 SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 PANTHER PTHR11807:SF2 5 409 8.8E-68 T 23-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 22 195 2.2E-54 T 23-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 350 392 4.7E-7 T 23-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 Pfam PF01171 PP-loop family 22 192 6.1E-55 T 23-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal SPYM18_RS00050 8f19fdebb83191b86989b030e8c9720c 428 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 4 290 22.739 T 23-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 SPYM18_RS05565 c1d157652aa1525564fb846f8148177b 95 Pfam PF07659 Domain of Unknown Function (DUF1599) 24 84 5.5E-12 T 23-04-2016 IPR011630 Clostridium phage phiCTP1, Gp74 SPYM18_RS02455 f1b1ac9eeae0a4f5593f5f71326202ed 308 Gene3D G3DSA:3.90.550.10 2 135 8.0E-27 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02455 f1b1ac9eeae0a4f5593f5f71326202ed 308 PANTHER PTHR10859 1 307 1.1E-128 T 23-04-2016 SPYM18_RS02455 f1b1ac9eeae0a4f5593f5f71326202ed 308 SUPERFAMILY SSF53448 2 256 4.78E-39 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS02455 f1b1ac9eeae0a4f5593f5f71326202ed 308 PANTHER PTHR10859:SF81 1 307 1.1E-128 T 23-04-2016 SPYM18_RS02455 f1b1ac9eeae0a4f5593f5f71326202ed 308 Pfam PF00535 Glycosyl transferase family 2 5 167 7.3E-32 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 SMART SM00382 28 230 5.5E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 PANTHER PTHR24220:SF85 5 255 3.5E-129 T 23-04-2016 SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 Gene3D G3DSA:3.40.50.300 3 232 4.3E-46 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 PANTHER PTHR24220 5 255 3.5E-129 T 23-04-2016 SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 SUPERFAMILY SSF52540 3 230 9.32E-43 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 Pfam PF00005 ABC transporter 19 171 6.1E-23 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01305 39ae583db016f8a1f530d995b3a5c9ba 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 242 2.3E-109 T 23-04-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 63 74 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 127 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 2.9E-35 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 124 152 - T 23-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 Pfam PF00106 short chain dehydrogenase 3 178 1.2E-43 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 Gene3D G3DSA:3.40.50.720 2 231 7.5E-65 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PANTHER PTHR24322 137 168 9.9E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PANTHER PTHR24322 7 121 9.9E-41 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 SUPERFAMILY SSF51735 3 231 5.33E-64 T 23-04-2016 IPR016040 NAD(P)-binding domain SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 63 74 1.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 156 1.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS02125 141ccc0444029cc192c08679bff7213e 232 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 117 125 1.1E-10 T 23-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR SPYM18_RS08030 1e9c2afbe0319a51d691008f94885c37 197 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 6 192 6.7E-49 T 23-04-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane SPYM18_RS08030 1e9c2afbe0319a51d691008f94885c37 197 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 4 192 1.3E-54 T 23-04-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 PANTHER PTHR24220:SF327 7 244 6.9E-140 T 23-04-2016 SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 SMART SM00382 30 217 8.9E-15 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 SUPERFAMILY SSF52540 5 239 3.55E-81 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 Gene3D G3DSA:3.40.50.300 4 241 2.6E-86 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 Pfam PF00005 ABC transporter 21 169 4.5E-37 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 PIRSF PIRSF039085 2 244 5.2E-115 T 23-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 SPYM18_RS06560 26c0af7cd56b32465260d382e7d6cb0f 244 PANTHER PTHR24220 7 244 6.9E-140 T 23-04-2016 SPYM18_RS06165 9ccb419d6468eafa61353ef1ca1696b5 231 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 8 220 1.4E-60 T 23-04-2016 IPR011737 Conserved hypothetical protein CHP02206, TP0381 SPYM18_RS06165 9ccb419d6468eafa61353ef1ca1696b5 231 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 16 206 6.4E-32 T 23-04-2016 IPR011737 Conserved hypothetical protein CHP02206, TP0381 SPYM18_RS07835 aa9d49397bdd53b9568ee1458b9a6198 119 PIRSF PIRSF021265 1 119 1.9E-58 T 23-04-2016 IPR010360 Protein of unknown function DUF956 SPYM18_RS07835 aa9d49397bdd53b9568ee1458b9a6198 119 Pfam PF06115 Domain of unknown function (DUF956) 1 116 7.7E-45 T 23-04-2016 IPR010360 Protein of unknown function DUF956 SPYM18_RS08955 0c52dc6c16f097d315a87282bfe25267 538 Pfam PF05257 CHAP domain 422 507 9.4E-17 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS08955 0c52dc6c16f097d315a87282bfe25267 538 SUPERFAMILY SSF54001 402 519 1.57E-17 T 23-04-2016 SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 163 1.6E-47 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 35.988 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 SUPERFAMILY SSF50249 1 163 2.36E-55 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 Pfam PF00436 Single-strand binding protein family 2 103 3.0E-35 T 23-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 PIRSF PIRSF002070 1 155 2.2E-36 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 Gene3D G3DSA:2.40.50.140 1 163 6.3E-47 T 23-04-2016 IPR012340 Nucleic acid-binding, OB-fold SPYM18_RS08170 8aa3a8d0296d446af227003f989af549 163 PANTHER PTHR10302 1 163 4.3E-44 T 23-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 SUPERFAMILY SSF51569 2 222 7.69E-62 T 23-04-2016 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 Pfam PF01487 Type I 3-dehydroquinase 6 218 5.5E-50 T 23-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 PANTHER PTHR21089 1 225 1.5E-68 T 23-04-2016 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 Gene3D G3DSA:3.20.20.70 2 224 2.3E-68 T 23-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 3 218 1.5E-44 T 23-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 PANTHER PTHR21089:SF5 1 225 1.5E-68 T 23-04-2016 SPYM18_RS03750 14ecfe3565b4cdf76a27c9f291e7a2f5 228 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 222 35.047 T 23-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 SPYM18_RS08160 69922ab4cbc15023c966778de3a9deb4 218 PIRSF PIRSF033111 1 218 9.0E-107 T 23-04-2016 IPR009214 Protein of unknown function DUF1129 SPYM18_RS08160 69922ab4cbc15023c966778de3a9deb4 218 Pfam PF06570 Protein of unknown function (DUF1129) 5 211 2.0E-78 T 23-04-2016 IPR009214 Protein of unknown function DUF1129 SPYM18_RS05250 f4443aab07b4c3e4c2a928b87c7f28c9 179 PANTHER PTHR34297 17 148 1.7E-44 T 23-04-2016 SPYM18_RS05250 f4443aab07b4c3e4c2a928b87c7f28c9 179 PANTHER PTHR34297:SF1 17 148 1.7E-44 T 23-04-2016 SPYM18_RS05250 f4443aab07b4c3e4c2a928b87c7f28c9 179 Pfam PF03780 Asp23 family, cell envelope-related function 18 124 2.6E-31 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 78 22.602 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 Gene3D G3DSA:4.10.640.10 13 78 6.0E-34 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 SUPERFAMILY SSF46911 6 78 1.57E-30 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 23-04-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 PANTHER PTHR13479 10 79 1.3E-32 T 23-04-2016 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 10 77 3.6E-31 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 Pfam PF01084 Ribosomal protein S18 22 73 7.6E-29 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.4E-20 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.4E-20 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.4E-20 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.4E-20 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS08165 92abc85feaf78c16cd04bb1c998b3853 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 4.0E-25 T 23-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS03105 a202caede8d71b460f7c66e3449d2418 79 SUPERFAMILY SSF46785 12 63 3.95E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS03105 a202caede8d71b460f7c66e3449d2418 79 Gene3D G3DSA:1.10.10.10 8 73 1.3E-5 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 PANTHER PTHR10681 64 192 8.1E-24 T 23-04-2016 SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 Pfam PF00578 AhpC/TSA family 70 188 2.3E-18 T 23-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 Gene3D G3DSA:3.40.30.10 2 28 1.9E-40 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 Gene3D G3DSA:3.40.30.10 64 205 1.9E-40 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 SUPERFAMILY SSF52833 67 205 1.93E-31 T 23-04-2016 IPR012336 Thioredoxin-like fold SPYM18_RS06780 b31f00390a87bcf49569898011ee1183 207 PANTHER PTHR10681:SF104 64 192 8.1E-24 T 23-04-2016 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 Pfam PF01418 Helix-turn-helix domain, rpiR family 7 80 7.1E-11 T 23-04-2016 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 PANTHER PTHR30514 7 253 5.8E-51 T 23-04-2016 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 Pfam PF01380 SIS domain 122 211 9.0E-16 T 23-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 SUPERFAMILY SSF46689 6 81 8.96E-11 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 Gene3D G3DSA:3.40.50.10490 69 253 1.4E-29 T 23-04-2016 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 PANTHER PTHR30514:SF1 7 253 5.8E-51 T 23-04-2016 SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 Gene3D G3DSA:1.10.10.10 4 68 1.9E-13 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01195 8d324ac7a3aee44abbb12174b3277ae5 276 SUPERFAMILY SSF53697 92 255 3.66E-29 T 23-04-2016 SPYM18_RS03190 9d455ae22450bdcd9c4e5a0d09018d88 241 Pfam PF07852 Protein of unknown function (DUF1642) 108 240 6.4E-29 T 23-04-2016 IPR012865 Protein of unknown function DUF1642 SPYM18_RS05230 4a26b2c8c6bc6d4a887ae1acb71fec82 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 55 2.7E-7 T 23-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 SPYM18_RS05230 4a26b2c8c6bc6d4a887ae1acb71fec82 180 SUPERFAMILY SSF46689 4 70 2.92E-13 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS05230 4a26b2c8c6bc6d4a887ae1acb71fec82 180 Gene3D G3DSA:1.10.357.10 3 173 7.5E-17 T 23-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 SPYM18_RS05230 4a26b2c8c6bc6d4a887ae1acb71fec82 180 PANTHER PTHR30055 1 174 3.0E-25 T 23-04-2016 SPYM18_RS05230 4a26b2c8c6bc6d4a887ae1acb71fec82 180 PANTHER PTHR30055:SF55 1 174 3.0E-25 T 23-04-2016 SPYM18_RS07795 4b166e08371e3e50554f091b16366053 113 Gene3D G3DSA:1.10.260.40 7 102 2.5E-7 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS07795 4b166e08371e3e50554f091b16366053 113 SUPERFAMILY SSF47413 6 64 8.0E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS01175 f51a95c189db7ae22e3a5879da73adbb 151 Gene3D G3DSA:2.60.120.370 1 149 7.4E-40 T 23-04-2016 IPR004375 YhcH/YjgK/YiaL family SPYM18_RS01175 f51a95c189db7ae22e3a5879da73adbb 151 SUPERFAMILY SSF51197 1 149 3.3E-36 T 23-04-2016 SPYM18_RS01175 f51a95c189db7ae22e3a5879da73adbb 151 TIGRFAM TIGR00022 TIGR00022: YhcH/YjgK/YiaL family protein 3 150 3.3E-28 T 23-04-2016 IPR004375 YhcH/YjgK/YiaL family SPYM18_RS01175 f51a95c189db7ae22e3a5879da73adbb 151 PANTHER PTHR34986 2 150 3.0E-37 T 23-04-2016 SPYM18_RS01175 f51a95c189db7ae22e3a5879da73adbb 151 Pfam PF04074 Domain of unknown function (DUF386) 1 147 7.2E-34 T 23-04-2016 IPR004375 YhcH/YjgK/YiaL family SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 20 420 2.6E-107 T 23-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 PANTHER PTHR11647:SF70 1 420 2.3E-163 T 23-04-2016 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 Gene3D G3DSA:2.30.40.10 1 68 2.8E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 23-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 PANTHER PTHR11647 1 420 2.3E-163 T 23-04-2016 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 SUPERFAMILY SSF51556 54 365 3.54E-91 T 23-04-2016 IPR032466 Metal-dependent hydrolase SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 23-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 422 37.717 T 23-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 Gene3D G3DSA:3.20.20.140 69 405 5.7E-92 T 23-04-2016 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 Pfam PF01979 Amidohydrolase family 50 419 1.2E-27 T 23-04-2016 IPR006680 Amidohydrolase-related GO:0016787 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 SUPERFAMILY SSF51338 2 53 1.5E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS04160 a942f118c5da59dc1d884fc3218a3e27 422 SUPERFAMILY SSF51338 366 421 1.5E-23 T 23-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 SPYM18_RS04470 f2d01c9538977140d0fcdd7a84dc9689 163 Gene3D G3DSA:3.40.35.10 1 162 3.9E-48 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS04470 f2d01c9538977140d0fcdd7a84dc9689 163 Pfam PF03830 PTS system sorbose subfamily IIB component 2 154 9.2E-43 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS04470 f2d01c9538977140d0fcdd7a84dc9689 163 PANTHER PTHR33799 1 163 1.8E-30 T 23-04-2016 SPYM18_RS04470 f2d01c9538977140d0fcdd7a84dc9689 163 SUPERFAMILY SSF52728 1 162 3.53E-41 T 23-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 SPYM18_RS02960 748be4d63e06941737388389772869cc 260 PANTHER PTHR32502:SF8 1 242 3.7E-31 T 23-04-2016 SPYM18_RS02960 748be4d63e06941737388389772869cc 260 Pfam PF03609 PTS system sorbose-specific iic component 5 236 1.7E-59 T 23-04-2016 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 SPYM18_RS02960 748be4d63e06941737388389772869cc 260 PANTHER PTHR32502 1 242 3.7E-31 T 23-04-2016 SPYM18_RS05425 9450689f74527c4cc12984507fb91db9 683 Pfam PF06605 Prophage endopeptidase tail 95 367 8.7E-14 T 23-04-2016 IPR010572 Prophage tail endopeptidase SPYM18_RS05425 9450689f74527c4cc12984507fb91db9 683 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 29 359 5.5E-20 T 23-04-2016 IPR007119 Phage minor structural protein, N-terminal domain SPYM18_RS01940 bca82fd412e16024511b8d07b13f975c 216 SMART SM00014 87 199 8.1E-26 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS01940 bca82fd412e16024511b8d07b13f975c 216 SUPERFAMILY SSF48317 7 211 2.75E-40 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS01940 bca82fd412e16024511b8d07b13f975c 216 PANTHER PTHR14969 30 203 1.6E-31 T 23-04-2016 SPYM18_RS01940 bca82fd412e16024511b8d07b13f975c 216 Gene3D G3DSA:1.20.144.10 48 204 6.1E-30 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS01940 bca82fd412e16024511b8d07b13f975c 216 Pfam PF01569 PAP2 superfamily 93 206 9.2E-22 T 23-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase SPYM18_RS08940 376df9c4049112337a80c3cceb2524b4 400 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 377 397 1.9E-18 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS08940 376df9c4049112337a80c3cceb2524b4 400 PRINTS PR00015 Gram-positive coccus surface protein anchor signature 361 376 1.9E-18 T 23-04-2016 IPR019950 Surface protein from Gram-positive cocci, anchor region SPYM18_RS08940 376df9c4049112337a80c3cceb2524b4 400 Pfam PF00746 Gram positive anchor 361 396 9.5E-11 T 23-04-2016 IPR019948 Gram-positive anchor SPYM18_RS08940 376df9c4049112337a80c3cceb2524b4 400 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 366 398 2.2E-6 T 23-04-2016 IPR019931 LPXTG cell wall anchor domain SPYM18_RS08940 376df9c4049112337a80c3cceb2524b4 400 Gene3D G3DSA:1.20.58.430 219 312 1.9E-4 T 23-04-2016 IPR023220 Type IV secretion system, VirB5-domain SPYM18_RS04630 dea1346dd6fa4a0d7c220e38b6650661 243 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 11 223 3.4E-43 T 23-04-2016 IPR005519 Acid phosphatase, class B-like SPYM18_RS04630 dea1346dd6fa4a0d7c220e38b6650661 243 TIGRFAM TIGR01672 AphA: HAD phosphatase, family IIIB 1 243 2.8E-125 T 23-04-2016 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00627+3.1.3.2|MetaCyc: PWY-6348 SPYM18_RS04630 dea1346dd6fa4a0d7c220e38b6650661 243 SUPERFAMILY SSF56784 36 242 1.05E-55 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04630 dea1346dd6fa4a0d7c220e38b6650661 243 Gene3D G3DSA:3.40.50.1000 35 242 1.6E-61 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS04630 dea1346dd6fa4a0d7c220e38b6650661 243 PIRSF PIRSF017818 1 243 2.4E-118 T 23-04-2016 IPR010025 HAD-superfamily phosphatase, subfamily IIIB, AphA GO:0003993|GO:0030288 KEGG: 00627+3.1.3.2|MetaCyc: PWY-6348 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 SMART SM00047 2 145 7.8E-24 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 SUPERFAMILY SSF54001 184 296 6.28E-7 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PANTHER PTHR33308 16 160 1.0E-21 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 15 140 8.0E-18 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PANTHER PTHR33308:SF3 16 160 1.0E-21 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PRINTS PR01002 Flagellar protein FlgJ signature 102 121 2.1E-8 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PRINTS PR01002 Flagellar protein FlgJ signature 122 140 2.1E-8 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PRINTS PR01002 Flagellar protein FlgJ signature 35 56 2.1E-8 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 PRINTS PR01002 Flagellar protein FlgJ signature 80 101 2.1E-8 T 23-04-2016 SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 Pfam PF08460 Bacterial SH3 domain 322 384 2.8E-7 T 23-04-2016 IPR003646 SH3-like domain, bacterial-type SPYM18_RS06230 970cfd033d215f46451b3aebe6b6803c 401 Pfam PF05257 CHAP domain 180 267 1.2E-8 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS06940 18acb7c0b31b02095e005d8aae160ed9 258 Hamap MF_01114 Regulatory protein RecX [recX]. 38 203 17.331 T 23-04-2016 IPR003783 Regulatory protein RecX GO:0006282 SPYM18_RS06940 18acb7c0b31b02095e005d8aae160ed9 258 Pfam PF02631 RecX family 80 198 7.7E-28 T 23-04-2016 IPR003783 Regulatory protein RecX GO:0006282 SPYM18_RS06940 18acb7c0b31b02095e005d8aae160ed9 258 Gene3D G3DSA:1.10.10.10 104 149 8.2E-7 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS06940 18acb7c0b31b02095e005d8aae160ed9 258 PANTHER PTHR33602:SF1 1 222 6.3E-31 T 23-04-2016 SPYM18_RS06940 18acb7c0b31b02095e005d8aae160ed9 258 PANTHER PTHR33602 1 222 6.3E-31 T 23-04-2016 SPYM18_RS03310 d0df4e345b1d22f0329954b6203a4013 336 Pfam PF07212 Hyaluronidase protein (HylP) 56 334 2.6E-167 T 23-04-2016 IPR009860 Hyaluronidase, bacterial GO:0004415|GO:0045227 KEGG: 00531+3.2.1.35 SPYM18_RS03310 d0df4e345b1d22f0329954b6203a4013 336 SUPERFAMILY SSF69349 7 332 1.57E-123 T 23-04-2016 SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 211 238 4.1E-48 T 23-04-2016 IPR009148 Streptococcal non-M secreted SibA SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 366 389 4.1E-48 T 23-04-2016 IPR009148 Streptococcal non-M secreted SibA SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 323 347 4.1E-48 T 23-04-2016 IPR009148 Streptococcal non-M secreted SibA SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 298 320 4.1E-48 T 23-04-2016 IPR009148 Streptococcal non-M secreted SibA SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 Pfam PF05257 CHAP domain 295 373 4.5E-14 T 23-04-2016 IPR007921 CHAP domain SPYM18_RS00240 70894ae971afd1007ed749dcb3e10de1 398 SUPERFAMILY SSF54001 294 390 7.85E-23 T 23-04-2016 SPYM18_RS00940 208568c166308f3f5f9f9eabaad0e5fc 477 PANTHER PTHR33843:SF5 2 477 1.7E-114 T 23-04-2016 SPYM18_RS00940 208568c166308f3f5f9f9eabaad0e5fc 477 Pfam PF03611 PTS system sugar-specific permease component 14 420 7.0E-112 T 23-04-2016 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SPYM18_RS00940 208568c166308f3f5f9f9eabaad0e5fc 477 PANTHER PTHR33843 2 477 1.7E-114 T 23-04-2016 SPYM18_RS05350 6c5c36a5384afa11fc0be000c363cd1d 204 Pfam PF09335 SNARE associated Golgi protein 74 191 4.3E-16 T 23-04-2016 IPR032816 SNARE associated Golgi protein SPYM18_RS04525 a458a666587a0abf0bb147627a0137ff 323 Gene3D G3DSA:1.10.10.60 7 46 5.7E-8 T 23-04-2016 IPR009057 Homeodomain-like GO:0003677 SPYM18_RS04525 a458a666587a0abf0bb147627a0137ff 323 Pfam PF13936 Helix-turn-helix domain 8 51 1.2E-16 T 23-04-2016 IPR025246 Transposase IS30-like HTH domain SPYM18_RS04525 a458a666587a0abf0bb147627a0137ff 323 SUPERFAMILY SSF53098 176 314 5.88E-18 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS04525 a458a666587a0abf0bb147627a0137ff 323 PANTHER PTHR10948 4 323 1.1E-80 T 23-04-2016 SPYM18_RS04525 a458a666587a0abf0bb147627a0137ff 323 Gene3D G3DSA:3.30.420.10 179 314 3.9E-10 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS08610 80e4d1eafadeb1c054f8a4c47a6dee42 111 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 8 105 1.8E-11 T 23-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family SPYM18_RS08610 80e4d1eafadeb1c054f8a4c47a6dee42 111 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 107 2.0E-19 T 23-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family SPYM18_RS02930 aac748f14575c796c53b3fd65f8a0f49 433 SMART SM00471 49 181 4.3E-11 T 23-04-2016 IPR003607 HD/PDEase domain SPYM18_RS02930 aac748f14575c796c53b3fd65f8a0f49 433 Pfam PF01966 HD domain 53 174 1.1E-10 T 23-04-2016 IPR006674 HD domain SPYM18_RS02930 aac748f14575c796c53b3fd65f8a0f49 433 PANTHER PTHR11373 1 334 1.5E-87 T 23-04-2016 SPYM18_RS02930 aac748f14575c796c53b3fd65f8a0f49 433 Gene3D G3DSA:1.10.3210.10 2 253 3.1E-82 T 23-04-2016 IPR006674 HD domain SPYM18_RS02930 aac748f14575c796c53b3fd65f8a0f49 433 SUPERFAMILY SSF109604 2 411 1.18E-123 T 23-04-2016 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 96 2.0E-46 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 1 116 21.287 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 Pfam PF02033 Ribosome-binding factor A 5 109 1.9E-30 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 SUPERFAMILY SSF89919 1 112 6.15E-31 T 23-04-2016 IPR023799 Ribosome-binding factor A domain SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 PANTHER PTHR33515 1 115 2.1E-38 T 23-04-2016 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 114 3.2E-30 T 23-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 Gene3D G3DSA:3.30.300.20 1 115 3.4E-38 T 23-04-2016 IPR015946 K homology domain-like, alpha/beta SPYM18_RS07420 417dee60cf42489d5c7ede5f7b639d5c 116 ProSitePatterns PS01319 Ribosome-binding factor A signature. 75 96 - T 23-04-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 SPYM18_RS04440 8bffb9d8d2c1174aa3a0c62518f2687f 210 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 7 196 1.6E-47 T 23-04-2016 IPR010178 Integral membrane protein 1906 SPYM18_RS04440 8bffb9d8d2c1174aa3a0c62518f2687f 210 Pfam PF07314 Protein of unknown function (DUF1461) 8 180 3.9E-44 T 23-04-2016 IPR010178 Integral membrane protein 1906 SPYM18_RS09455 e1a3c85c8b062e5d71be4aa2779ba388 360 Pfam PF13349 Putative adhesin 51 360 2.0E-58 T 23-04-2016 IPR025164 Putative adhesin SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 23-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 PANTHER PTHR24220:SF336 7 276 3.6E-129 T 23-04-2016 SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 262 1.1E-7 T 23-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 SMART SM00382 34 228 2.2E-12 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 PANTHER PTHR24220 7 276 3.6E-129 T 23-04-2016 SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 SUPERFAMILY SSF52540 5 250 5.46E-68 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 Gene3D G3DSA:3.40.50.300 3 272 1.9E-78 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01360 7ecdd4e978f4e9404646613bdc1a5e27 307 Pfam PF00005 ABC transporter 25 178 1.3E-29 T 23-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 SPYM18_RS06345 3d43176bff3d8ea5e648d529b90b23a6 471 SUPERFAMILY SSF52540 75 198 3.23E-7 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06345 3d43176bff3d8ea5e648d529b90b23a6 471 Gene3D G3DSA:3.40.50.300 75 219 1.8E-6 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS01830 f231c23b26eca7dc52e8f82e12e1138b 160 PANTHER PTHR10908 1 160 3.8E-27 T 23-04-2016 SPYM18_RS01830 f231c23b26eca7dc52e8f82e12e1138b 160 Gene3D G3DSA:3.40.630.30 2 159 6.1E-36 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS01830 f231c23b26eca7dc52e8f82e12e1138b 160 Pfam PF13673 Acetyltransferase (GNAT) domain 42 159 3.9E-9 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS01830 f231c23b26eca7dc52e8f82e12e1138b 160 SUPERFAMILY SSF55729 2 160 1.36E-20 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS06495 b734f90de014c75d276b1a886fe73c23 195 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 8 193 2.7E-64 T 23-04-2016 IPR018672 Protein of unknown function DUF2140 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 SUPERFAMILY SSF53335 61 251 9.97E-18 T 23-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 PANTHER PTHR32319:SF0 1 267 1.6E-121 T 23-04-2016 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 PANTHER PTHR32319 1 267 1.6E-121 T 23-04-2016 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 PIRSF PIRSF005578 1 268 1.2E-96 T 23-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 Pfam PF01728 FtsJ-like methyltransferase 62 242 5.4E-16 T 23-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 SUPERFAMILY SSF55174 3 71 2.8E-9 T 23-04-2016 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 SMART SM00363 4 71 2.6E-5 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 239 1.5E-78 T 23-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 Gene3D G3DSA:3.10.290.10 4 104 2.2E-18 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS06525 2d5c55a7b0e06f08591ad9883421a3ce 275 Pfam PF01479 S4 domain 4 52 3.0E-6 T 23-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 SPYM18_RS08385 6c2d3ac7fb7bf8e54cf8ebf2fbb78a08 183 Pfam PF06081 Aromatic acid exporter family member 1 19 165 8.0E-14 T 23-04-2016 IPR010343 Aromatic acid exporter family member 1 SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 PANTHER PTHR11751:SF303 9 401 6.5E-162 T 23-04-2016 SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 Pfam PF00155 Aminotransferase class I and II 34 393 1.7E-46 T 23-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 Gene3D G3DSA:3.40.640.10 51 279 7.4E-64 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 Gene3D G3DSA:3.90.1150.10 280 403 4.6E-37 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 SUPERFAMILY SSF53383 7 401 1.77E-90 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS07985 561460515005cad6f0f4cce26fe7d3ed 404 PANTHER PTHR11751 9 401 6.5E-162 T 23-04-2016 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 96 1.5E-14 T 23-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 Gene3D G3DSA:3.40.140.10 4 126 6.7E-49 T 23-04-2016 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 23-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 SUPERFAMILY SSF53927 5 126 4.02E-45 T 23-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 PANTHER PTHR11644 5 126 1.6E-55 T 23-04-2016 SPYM18_RS05110 8f3278fc7315af0fae4a7e21b527c1c3 129 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 126 7.4E-43 T 23-04-2016 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 Gene3D G3DSA:3.30.420.40 145 302 3.9E-55 T 23-04-2016 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 Pfam PF00480 ROK family 6 319 7.7E-72 T 23-04-2016 IPR000600 ROK family SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 PANTHER PTHR18964 1 319 7.9E-95 T 23-04-2016 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 Gene3D G3DSA:3.30.420.40 4 144 8.3E-42 T 23-04-2016 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 321 6.8E-98 T 23-04-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 ProSitePatterns PS01125 ROK family signature. 139 166 - T 23-04-2016 IPR000600 ROK family SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 SUPERFAMILY SSF53067 4 320 4.08E-69 T 23-04-2016 SPYM18_RS06660 cb6354869fa4abc4b94b906b220c1a91 323 PANTHER PTHR18964:SF123 1 319 7.9E-95 T 23-04-2016 SPYM18_RS06850 9ceef18427980ddfaf69132eba0755d3 112 Gene3D G3DSA:2.60.120.10 2 111 3.4E-34 T 23-04-2016 IPR014710 RmlC-like jelly roll fold SPYM18_RS06850 9ceef18427980ddfaf69132eba0755d3 112 Pfam PF07883 Cupin domain 41 107 1.1E-10 T 23-04-2016 IPR013096 Cupin 2, conserved barrel SPYM18_RS06850 9ceef18427980ddfaf69132eba0755d3 112 PANTHER PTHR37694 2 110 6.7E-27 T 23-04-2016 SPYM18_RS06850 9ceef18427980ddfaf69132eba0755d3 112 SUPERFAMILY SSF51182 4 109 5.2E-25 T 23-04-2016 IPR011051 RmlC-like cupin domain SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 Pfam PF01022 Bacterial regulatory protein, arsR family 41 87 1.1E-11 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 Gene3D G3DSA:1.10.10.10 2 111 1.7E-26 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 SMART SM00418 34 112 1.5E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 PANTHER PTHR33154 45 111 5.5E-13 T 23-04-2016 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 SUPERFAMILY SSF46785 19 111 3.07E-19 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 2.3E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 2.3E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 2.3E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 2.3E-13 T 23-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 SPYM18_RS09405 82f3a9033a7d74b4f693a6761ed98017 112 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 23-04-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 SPYM18_RS05205 fce3402389911affc6d2a9dd3a364e32 446 PIRSF PIRSF005850 1 446 2.7E-160 T 23-04-2016 IPR019219 Protein of unknown function DUF2130 SPYM18_RS05205 fce3402389911affc6d2a9dd3a364e32 446 Pfam PF09903 Uncharacterized protein conserved in bacteria (DUF2130) 175 431 9.9E-90 T 23-04-2016 IPR019219 Protein of unknown function DUF2130 SPYM18_RS09000 3c3b78e76f1b30bd2300c8e93e0c09b3 309 Gene3D G3DSA:3.10.50.40 156 261 5.4E-10 T 23-04-2016 SPYM18_RS09000 3c3b78e76f1b30bd2300c8e93e0c09b3 309 Hamap MF_01145 Foldase protein PrsA [prsA]. 5 299 18.626 T 23-04-2016 IPR023059 Foldase protein PrsA GO:0003755 SPYM18_RS09000 3c3b78e76f1b30bd2300c8e93e0c09b3 309 Pfam PF13145 PPIC-type PPIASE domain 134 250 4.7E-11 T 23-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 SPYM18_RS09000 3c3b78e76f1b30bd2300c8e93e0c09b3 309 SUPERFAMILY SSF109998 33 176 1.18E-17 T 23-04-2016 IPR027304 Trigger factor/SurA domain SPYM18_RS09000 3c3b78e76f1b30bd2300c8e93e0c09b3 309 SUPERFAMILY SSF54534 152 242 1.81E-7 T 23-04-2016 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 330 4.6E-112 T 23-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 PANTHER PTHR30100:SF1 1 335 5.8E-123 T 23-04-2016 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 SUPERFAMILY SSF53659 2 327 3.33E-97 T 23-04-2016 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 Pfam PF02504 Fatty acid synthesis protein 3 320 4.2E-101 T 23-04-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UniPathway: UPA00085 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 335 140.717 T 23-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 PIRSF PIRSF002465 1 335 1.9E-123 T 23-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 PANTHER PTHR30100 1 335 5.8E-123 T 23-04-2016 SPYM18_RS00255 a719e53ed2de179e27cd7896d25d0c5a 335 Gene3D G3DSA:3.40.718.10 1 329 1.2E-126 T 23-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 SPYM18_RS01845 852bcfa63f31c45e929c326438ca7512 307 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 248 7.2E-47 T 23-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal SPYM18_RS01845 852bcfa63f31c45e929c326438ca7512 307 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 5 252 28.313 T 23-04-2016 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes SPYM18_RS01845 852bcfa63f31c45e929c326438ca7512 307 PANTHER PTHR12428:SF20 28 305 3.8E-89 T 23-04-2016 SPYM18_RS01845 852bcfa63f31c45e929c326438ca7512 307 Pfam PF02096 60Kd inner membrane protein 60 247 4.7E-43 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS01845 852bcfa63f31c45e929c326438ca7512 307 PANTHER PTHR12428 28 305 3.8E-89 T 23-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 SPYM18_RS05375 5a8d356b5b9b5fac2d94cab3b8709fa3 174 Pfam PF13274 Protein of unknown function (DUF4065) 26 139 2.2E-21 T 23-04-2016 IPR025272 Domain of unknown function DUF4065 SPYM18_RS06630 a4b4cc987cb04e368fccf51600dcb93a 382 Hamap MF_00912 Cell division protein DivIB [divIB]. 19 345 31.075 T 23-04-2016 IPR026580 Cell division protein DivIB SPYM18_RS06630 a4b4cc987cb04e368fccf51600dcb93a 382 Pfam PF08478 POTRA domain, FtsQ-type 126 195 1.3E-13 T 23-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type SPYM18_RS06630 a4b4cc987cb04e368fccf51600dcb93a 382 PANTHER PTHR37820 22 367 1.1E-28 T 23-04-2016 SPYM18_RS09365 6c25608d0473762ab1dfdc74676a3855 313 PIRSF PIRSF006483 20 313 1.4E-95 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS09365 6c25608d0473762ab1dfdc74676a3855 313 PANTHER PTHR33545:SF5 22 312 3.7E-101 T 23-04-2016 SPYM18_RS09365 6c25608d0473762ab1dfdc74676a3855 313 PANTHER PTHR33545 22 312 3.7E-101 T 23-04-2016 SPYM18_RS09365 6c25608d0473762ab1dfdc74676a3855 313 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 42 246 3.4E-54 T 23-04-2016 IPR003740 Uncharacterised membrane protein YitT SPYM18_RS09365 6c25608d0473762ab1dfdc74676a3855 313 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 252 307 6.6E-12 T 23-04-2016 IPR019264 Domain of unknown function DUF2179 SPYM18_RS01515 80237dcf62052aa5c280c65da10058b5 164 PANTHER PTHR30455 2 156 3.3E-67 T 23-04-2016 SPYM18_RS01515 80237dcf62052aa5c280c65da10058b5 164 Pfam PF03477 ATP cone domain 50 136 3.5E-18 T 23-04-2016 IPR005144 ATP-cone domain SPYM18_RS01515 80237dcf62052aa5c280c65da10058b5 164 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 146 1.1E-58 T 23-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SPYM18_RS01515 80237dcf62052aa5c280c65da10058b5 164 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 154 80.669 T 23-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 SPYM18_RS01515 80237dcf62052aa5c280c65da10058b5 164 PANTHER PTHR30455:SF2 2 156 3.3E-67 T 23-04-2016 SPYM18_RS01935 3399776b1590d1078839a4ae4da520dd 187 PANTHER PTHR38438 1 185 2.5E-42 T 23-04-2016 SPYM18_RS01935 3399776b1590d1078839a4ae4da520dd 187 PANTHER PTHR38438:SF1 1 185 2.5E-42 T 23-04-2016 SPYM18_RS01935 3399776b1590d1078839a4ae4da520dd 187 PIRSF PIRSF037778 1 187 7.3E-49 T 23-04-2016 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 SPYM18_RS01935 3399776b1590d1078839a4ae4da520dd 187 Pfam PF12822 Protein of unknown function (DUF3816) 6 175 1.4E-19 T 23-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 SPYM18_RS07380 d0a986fe7765912018d9a6bb5fdcdcfa 483 PIRSF PIRSF006304 6 482 1.3E-139 T 23-04-2016 IPR013853 Galactitol permease IIC component GO:0015577|GO:0015796 SPYM18_RS07380 d0a986fe7765912018d9a6bb5fdcdcfa 483 Pfam PF03611 PTS system sugar-specific permease component 23 410 7.9E-46 T 23-04-2016 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SPYM18_RS07380 d0a986fe7765912018d9a6bb5fdcdcfa 483 PANTHER PTHR37324 7 483 1.1E-81 T 23-04-2016 SPYM18_RS05240 3463742b60f1b75f072f096cae9189dc 162 Pfam PF03780 Asp23 family, cell envelope-related function 8 113 6.9E-29 T 23-04-2016 IPR005531 Alkaline shock protein Asp23 SPYM18_RS05240 3463742b60f1b75f072f096cae9189dc 162 PANTHER PTHR34297:SF1 1 137 4.3E-39 T 23-04-2016 SPYM18_RS05240 3463742b60f1b75f072f096cae9189dc 162 PANTHER PTHR34297 1 137 4.3E-39 T 23-04-2016 SPYM18_RS04900 486a46a784ad92f5062bd65d56d7eda0 467 PANTHER PTHR10283:SF87 1 461 2.9E-102 T 23-04-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 SPYM18_RS04900 486a46a784ad92f5062bd65d56d7eda0 467 TIGRFAM TIGR00784 citMHS: citrate transporter 68 458 5.9E-113 T 23-04-2016 IPR014738 Citrate transporter GO:0015137|GO:0015746 SPYM18_RS04900 486a46a784ad92f5062bd65d56d7eda0 467 PANTHER PTHR10283 1 461 2.9E-102 T 23-04-2016 SPYM18_RS04900 486a46a784ad92f5062bd65d56d7eda0 467 Pfam PF03600 Citrate transporter 14 409 8.2E-45 T 23-04-2016 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 Gene3D G3DSA:3.30.565.10 243 399 9.2E-20 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 Pfam PF00512 His Kinase A (phospho-acceptor) domain 195 255 3.2E-9 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 SMART SM00387 300 410 2.5E-5 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 302 398 3.3E-8 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 Gene3D G3DSA:1.10.287.130 192 242 7.0E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 SMART SM00388 194 256 1.2E-10 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 PANTHER PTHR24423 192 397 6.5E-29 T 23-04-2016 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 SUPERFAMILY SSF47384 188 255 5.49E-11 T 23-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 SPYM18_RS04020 6649cb874d91ff2a32decd88c343477d 410 SUPERFAMILY SSF55874 262 402 2.74E-19 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS09560 2ff191eed0c900baa18a6efd031700eb 419 SUPERFAMILY SSF53448 63 333 8.63E-39 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS09560 2ff191eed0c900baa18a6efd031700eb 419 Gene3D G3DSA:3.90.550.10 65 307 1.5E-26 T 23-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases SPYM18_RS09560 2ff191eed0c900baa18a6efd031700eb 419 Pfam PF00535 Glycosyl transferase family 2 68 237 7.1E-33 T 23-04-2016 IPR001173 Glycosyltransferase 2-like SPYM18_RS09560 2ff191eed0c900baa18a6efd031700eb 419 PANTHER PTHR22913 60 411 5.4E-46 T 23-04-2016 IPR026107 Hyaluronan synthase/nodulation protein C SPYM18_RS09560 2ff191eed0c900baa18a6efd031700eb 419 PANTHER PTHR22913:SF12 60 411 5.4E-46 T 23-04-2016 SPYM18_RS05245 3954e7617e7e25ae3e79011bcc6b5c79 66 Gene3D G3DSA:1.10.1470.10 4 64 6.9E-17 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS05245 3954e7617e7e25ae3e79011bcc6b5c79 66 Pfam PF05532 CsbD-like 4 55 1.8E-15 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS05245 3954e7617e7e25ae3e79011bcc6b5c79 66 SUPERFAMILY SSF69047 2 60 1.05E-12 T 23-04-2016 IPR008462 CsbD-like SPYM18_RS09515 64a76368e68b34ab3260204bb0619aaf 290 PANTHER PTHR30182 1 289 1.8E-129 T 23-04-2016 SPYM18_RS09515 64a76368e68b34ab3260204bb0619aaf 290 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 1.5E-109 T 23-04-2016 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 SPYM18_RS09515 64a76368e68b34ab3260204bb0619aaf 290 Pfam PF03313 Serine dehydratase alpha chain 19 275 2.7E-72 T 23-04-2016 IPR005130 Serine dehydratase-like, alpha subunit SPYM18_RS02670 ca3ffb2d40cc34de7885e6b26a8e1ba5 101 SUPERFAMILY SSF143011 4 96 8.5E-7 T 23-04-2016 SPYM18_RS02670 ca3ffb2d40cc34de7885e6b26a8e1ba5 101 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 5 101 1.2E-19 T 23-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family SPYM18_RS02670 ca3ffb2d40cc34de7885e6b26a8e1ba5 101 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 96 2.0E-15 T 23-04-2016 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 SUPERFAMILY SSF52540 18 285 2.58E-59 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 SUPERFAMILY SSF54752 286 343 1.07E-19 T 23-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PANTHER PTHR22942:SF1 5 353 1.7E-195 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 224 252 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 179 208 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 107 136 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 261 290 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 315 332 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PRINTS PR00142 RecA protein signature 141 170 1.8E-81 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 Gene3D G3DSA:3.40.50.300 40 285 2.9E-75 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 SMART SM00382 71 242 6.0E-8 T 23-04-2016 IPR003593 AAA+ ATPase domain SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 Gene3D G3DSA:3.30.250.10 286 344 2.9E-26 T 23-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 ProSitePatterns PS00321 recA signature. 227 235 - T 23-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 PANTHER PTHR22942 5 353 1.7E-195 T 23-04-2016 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 Hamap MF_00268 Protein RecA [recA]. 19 347 51.122 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 18 341 2.6E-162 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS09300 162b253079f77882b7354c2bb2c7eb4a 378 Pfam PF00154 recA bacterial DNA recombination protein 21 286 9.9E-140 T 23-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 SPYM18_RS02550 651c8bd143d55d7245e5f035c4797c43 189 SUPERFAMILY SSF54637 92 176 2.24E-5 T 23-04-2016 IPR029069 HotDog domain SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Pfam PF02821 Staphylokinase/Streptokinase family 53 166 1.1E-27 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Pfam PF02821 Staphylokinase/Streptokinase family 183 302 3.7E-30 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Pfam PF02821 Staphylokinase/Streptokinase family 312 425 4.1E-28 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Gene3D G3DSA:3.10.20.180 40 173 7.8E-61 T 23-04-2016 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Gene3D G3DSA:3.10.20.150 315 397 3.0E-42 T 23-04-2016 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 Gene3D G3DSA:3.10.20.180 177 313 2.9E-70 T 23-04-2016 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 SUPERFAMILY SSF54328 311 398 6.54E-40 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 SUPERFAMILY SSF54328 177 313 2.03E-54 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 SUPERFAMILY SSF54328 39 174 3.6E-62 T 23-04-2016 IPR004093 Staphylokinase/Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 410 425 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 137 154 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 197 213 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 262 279 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 118 134 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 297 316 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 344 358 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 373 389 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 170 185 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 234 248 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 29 43 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS08795 a045947988c6ad90674a770826d1d670 440 PRINTS PR01753 Streptococcus streptokinase protein signature 63 79 5.3E-110 T 23-04-2016 IPR008124 Streptokinase GO:0005576|GO:0009405|GO:0031639 SPYM18_RS04310 df89180dbbd23dd70a4d947d62f871c2 393 PANTHER PTHR21716 14 29 1.4E-74 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like SPYM18_RS04310 df89180dbbd23dd70a4d947d62f871c2 393 PANTHER PTHR21716 45 373 1.4E-74 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like SPYM18_RS04310 df89180dbbd23dd70a4d947d62f871c2 393 Pfam PF01594 Domain of unknown function DUF20 35 366 1.1E-68 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like SPYM18_RS08250 4ad2184e6927dc7296392e7ce5f52843 312 SUPERFAMILY SSF56601 5 303 1.74E-60 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS08250 4ad2184e6927dc7296392e7ce5f52843 312 Pfam PF00144 Beta-lactamase 7 293 4.3E-52 T 23-04-2016 IPR001466 Beta-lactamase-related SPYM18_RS08250 4ad2184e6927dc7296392e7ce5f52843 312 PANTHER PTHR22935 4 297 2.9E-44 T 23-04-2016 SPYM18_RS08250 4ad2184e6927dc7296392e7ce5f52843 312 Gene3D G3DSA:3.40.710.10 8 296 4.7E-53 T 23-04-2016 IPR012338 Beta-lactamase/transpeptidase-like SPYM18_RS08250 4ad2184e6927dc7296392e7ce5f52843 312 PANTHER PTHR22935:SF10 4 297 2.9E-44 T 23-04-2016 SPYM18_RS03650 1a3e44cb462b11b9e103bee3f4e7d543 384 Pfam PF09314 Domain of unknown function (DUF1972) 1 185 4.3E-101 T 23-04-2016 IPR015393 Domain of unknown function DUF1972 SPYM18_RS03650 1a3e44cb462b11b9e103bee3f4e7d543 384 SUPERFAMILY SSF53756 25 380 2.47E-23 T 23-04-2016 SPYM18_RS03590 08391355535f50a2f290efb38d3abc15 358 PANTHER PTHR30572:SF11 1 358 3.5E-31 T 23-04-2016 SPYM18_RS03590 08391355535f50a2f290efb38d3abc15 358 PANTHER PTHR30572 1 358 3.5E-31 T 23-04-2016 SPYM18_RS03590 08391355535f50a2f290efb38d3abc15 358 Pfam PF02687 FtsX-like permease family 243 353 3.0E-10 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS06785 ba269dbb608344049d5038d23460c70e 236 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 11 225 1.5E-54 T 23-04-2016 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 SPYM18_RS06785 ba269dbb608344049d5038d23460c70e 236 PANTHER PTHR31272 1 235 1.7E-71 T 23-04-2016 SPYM18_RS06785 ba269dbb608344049d5038d23460c70e 236 PANTHER PTHR31272:SF4 1 235 1.7E-71 T 23-04-2016 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 122 139 - T 23-04-2016 IPR001882 Biotin-binding site SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 95 108 5.4E-12 T 23-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 127 140 5.4E-12 T 23-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 126 5.4E-12 T 23-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 SUPERFAMILY SSF51230 92 165 4.45E-22 T 23-04-2016 IPR011053 Single hybrid motif SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 Gene3D G3DSA:2.40.50.100 91 166 2.1E-26 T 23-04-2016 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 Pfam PF00364 Biotin-requiring enzyme 93 165 3.8E-19 T 23-04-2016 IPR000089 Biotin/lipoyl attachment SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 166 1.1E-36 T 23-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 SPYM18_RS07865 3d163e5d9f817a1b8c44763dddbcb202 166 PANTHER PTHR23151 1 165 5.2E-28 T 23-04-2016 SPYM18_RS04645 04ca74d55d384e1fd3c200c5ffa6d167 375 Pfam PF01594 Domain of unknown function DUF20 43 360 4.7E-40 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like SPYM18_RS04645 04ca74d55d384e1fd3c200c5ffa6d167 375 PANTHER PTHR21716 40 361 7.8E-40 T 23-04-2016 IPR002549 Transmembrane protein TqsA-like SPYM18_RS01655 c282e42a421161d23f7a4170287a9fa1 275 SMART SM00244 24 190 2.9E-8 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS01655 c282e42a421161d23f7a4170287a9fa1 275 PANTHER PTHR10264 7 254 1.7E-13 T 23-04-2016 IPR001972 Stomatin family GO:0016020 SPYM18_RS01655 c282e42a421161d23f7a4170287a9fa1 275 SUPERFAMILY SSF117892 57 193 2.09E-10 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS01655 c282e42a421161d23f7a4170287a9fa1 275 PANTHER PTHR10264:SF78 7 254 1.7E-13 T 23-04-2016 SPYM18_RS01655 c282e42a421161d23f7a4170287a9fa1 275 Pfam PF01145 SPFH domain / Band 7 family 28 209 6.5E-23 T 23-04-2016 IPR001107 Band 7 domain SPYM18_RS05525 8d8f6330cb350934e5d7185e773b33c3 500 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 48 476 1.2E-95 T 23-04-2016 IPR021145 Portal protein, SPP1 Gp6-like SPYM18_RS05525 8d8f6330cb350934e5d7185e773b33c3 500 TIGRFAM TIGR01538 portal_SPP1: phage portal protein, SPP1 family 38 473 8.6E-192 T 23-04-2016 IPR006428 Portal protein, SPP1-type SPYM18_RS05580 c16504ab63bd7c1742877346e676421f 94 SMART SM00990 1 83 9.7E-15 T 23-04-2016 IPR014883 VRR-NUC domain GO:0016788 SPYM18_RS05580 c16504ab63bd7c1742877346e676421f 94 Pfam PF08774 VRR-NUC domain 18 82 7.5E-10 T 23-04-2016 IPR014883 VRR-NUC domain GO:0016788 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 PANTHER PTHR39209 1 234 1.3E-47 T 23-04-2016 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 PANTHER PTHR39209:SF2 1 234 1.3E-47 T 23-04-2016 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 Pfam PF03483 B3/4 domain 75 196 2.5E-21 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 SMART SM00873 64 210 1.3E-8 T 23-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 Gene3D G3DSA:3.50.40.10 79 195 2.4E-15 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPYM18_RS06755 4b644220c5fced11f7dfc234d4e173f4 238 SUPERFAMILY SSF56037 50 224 4.97E-29 T 23-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 SPYM18_RS07945 5ebdabdb6f33e9d6e62b0093491124a2 79 Pfam PF04226 Transglycosylase associated protein 31 75 7.5E-9 T 23-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 SPYM18_RS00825 68922f7611be64a2144a01923472ffa3 339 Pfam PF13303 Phosphotransferase system, EIIC 29 336 7.9E-64 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS00825 68922f7611be64a2144a01923472ffa3 339 PANTHER PTHR40063 2 339 1.0E-88 T 23-04-2016 SPYM18_RS02870 4fce2c1206c963f41087231602ec4f59 167 Pfam PF07155 ECF-type riboflavin transporter, S component 2 156 9.3E-7 T 23-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPYM18_RS06395 06ea651b00a35bf132d9492af69fe585 167 Pfam PF07852 Protein of unknown function (DUF1642) 35 166 5.1E-33 T 23-04-2016 IPR012865 Protein of unknown function DUF1642 SPYM18_RS07605 9621bd1605a86be39a2c5591cc915278 110 Pfam PF10665 Minor capsid protein 4 109 1.4E-38 T 23-04-2016 IPR019612 Minor capsid protein, putative SPYM18_RS06220 c42e79e8891473adf00856f8fe0febba 268 Pfam PF13930 DNA/RNA non-specific endonuclease 68 200 1.5E-25 T 23-04-2016 SPYM18_RS06220 c42e79e8891473adf00856f8fe0febba 268 SMART SM00892 60 249 1.1E-12 T 23-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 SPYM18_RS06030 cb9ded6c60c02eb6efb68c0e686f17f1 59 SUPERFAMILY SSF53098 1 53 7.4E-5 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS06030 cb9ded6c60c02eb6efb68c0e686f17f1 59 Pfam PF13333 Integrase core domain 2 55 1.1E-12 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS03920 b100332be16e69d33a31b2fa89805446 352 PANTHER PTHR41320 1 352 1.2E-73 T 23-04-2016 SPYM18_RS03920 b100332be16e69d33a31b2fa89805446 352 Pfam PF13303 Phosphotransferase system, EIIC 15 347 2.0E-91 T 23-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 SPYM18_RS06150 66bf760185836b30a8ad6dbd0ab6f059 666 PANTHER PTHR30540 20 455 5.1E-129 T 23-04-2016 SPYM18_RS06150 66bf760185836b30a8ad6dbd0ab6f059 666 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 9 647 27.245 T 23-04-2016 IPR023051 Potassium uptake protein, low affinity, Kup SPYM18_RS06150 66bf760185836b30a8ad6dbd0ab6f059 666 PANTHER PTHR30540:SF7 20 455 5.1E-129 T 23-04-2016 SPYM18_RS06150 66bf760185836b30a8ad6dbd0ab6f059 666 Pfam PF02705 K+ potassium transporter 18 551 2.7E-168 T 23-04-2016 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 SPYM18_RS09385 d719eff4d566ea898a6adb690a3b2700 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.5E-19 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 SPYM18_RS09385 d719eff4d566ea898a6adb690a3b2700 60 PANTHER PTHR35534 1 60 1.2E-26 T 23-04-2016 SPYM18_RS09385 d719eff4d566ea898a6adb690a3b2700 60 SUPERFAMILY SSF57829 2 54 4.15E-16 T 23-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 SPYM18_RS09385 d719eff4d566ea898a6adb690a3b2700 60 Pfam PF01783 Ribosomal L32p protein family 2 54 1.1E-18 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 SPYM18_RS09385 d719eff4d566ea898a6adb690a3b2700 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.158 T 23-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 SPYM18_RS01005 e52a015e38fee88a647ce1786afdfbfc 287 Pfam PF06161 Protein of unknown function (DUF975) 1 255 3.6E-74 T 23-04-2016 IPR010380 Protein of unknown function DUF975 SPYM18_RS01005 e52a015e38fee88a647ce1786afdfbfc 287 PANTHER PTHR40076:SF1 1 255 1.4E-19 T 23-04-2016 SPYM18_RS01005 e52a015e38fee88a647ce1786afdfbfc 287 PANTHER PTHR40076 1 255 1.4E-19 T 23-04-2016 SPYM18_RS03675 9af37a24a193cc15b61c497c5f8dcb5d 581 Pfam PF05045 Rhamnan synthesis protein F 34 514 1.2E-182 T 23-04-2016 IPR007739 Rhamnan synthesis F SPYM18_RS03245 45e29d68c60365b95a85f03773833e5e 406 Pfam PF04860 Phage portal protein 42 353 2.5E-44 T 23-04-2016 IPR006944 Bacteriophage/Gene transfer agent portal protein SPYM18_RS03245 45e29d68c60365b95a85f03773833e5e 406 TIGRFAM TIGR01537 portal_HK97: phage portal protein, HK97 family 34 348 8.2E-71 T 23-04-2016 IPR006427 Phage portal protein, HK97 SPYM18_RS01230 675140c4af6011e47a39aa3cd87987bc 423 PANTHER PTHR30563 1 423 1.7E-97 T 23-04-2016 SPYM18_RS01230 675140c4af6011e47a39aa3cd87987bc 423 SUPERFAMILY SSF58113 30 149 1.96E-5 T 23-04-2016 SPYM18_RS01230 675140c4af6011e47a39aa3cd87987bc 423 Gene3D G3DSA:1.20.120.20 34 150 1.5E-4 T 23-04-2016 SPYM18_RS01230 675140c4af6011e47a39aa3cd87987bc 423 Pfam PF02646 RmuC family 117 408 4.3E-73 T 23-04-2016 IPR003798 DNA recombination RmuC SPYM18_RS02075 4154f8c80f050387e46a90525c37790e 235 PANTHER PTHR37314:SF2 1 230 1.3E-30 T 23-04-2016 SPYM18_RS02075 4154f8c80f050387e46a90525c37790e 235 Pfam PF06912 Protein of unknown function (DUF1275) 18 213 1.3E-31 T 23-04-2016 IPR010699 Protein of unknown function DUF1275 SPYM18_RS02075 4154f8c80f050387e46a90525c37790e 235 PANTHER PTHR37314 1 230 1.3E-30 T 23-04-2016 SPYM18_RS00325 375ffee79477cf12d7865cd9bf71e1a5 303 SUPERFAMILY SSF47413 2 69 1.39E-10 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00325 375ffee79477cf12d7865cd9bf71e1a5 303 Gene3D G3DSA:1.10.260.40 5 120 8.9E-14 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS00325 375ffee79477cf12d7865cd9bf71e1a5 303 Pfam PF01381 Helix-turn-helix 12 64 2.3E-7 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS00325 375ffee79477cf12d7865cd9bf71e1a5 303 SMART SM00530 8 64 4.7E-5 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 Hamap MF_01041 UPF0223 protein . 3 90 24.019 T 23-04-2016 IPR007920 Protein of unknown function UPF0223 SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 4 81 2.0E-38 T 23-04-2016 IPR007920 Protein of unknown function UPF0223 SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 Gene3D G3DSA:1.10.220.80 14 91 9.3E-33 T 23-04-2016 IPR023324 BH2638-like domain SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 Pfam PF05256 Uncharacterised protein family (UPF0223) 4 86 2.5E-34 T 23-04-2016 IPR007920 Protein of unknown function UPF0223 SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 PIRSF PIRSF037260 1 92 3.9E-40 T 23-04-2016 IPR007920 Protein of unknown function UPF0223 SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 SUPERFAMILY SSF158504 7 88 3.14E-32 T 23-04-2016 IPR023324 BH2638-like domain SPYM18_RS05185 126c9bdc046f3c58bbf2fca9e5a2102f 92 PANTHER PTHR41305 4 92 4.6E-30 T 23-04-2016 SPYM18_RS00770 04b96684fe885f2ed745ffc2b0b4abee 189 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 70 137 2.9E-21 T 23-04-2016 IPR022464 Streptococcal pilin isopeptide linker SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 PANTHER PTHR30204 1 195 3.9E-26 T 23-04-2016 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 Gene3D G3DSA:1.10.1660.10 60 114 6.1E-6 T 23-04-2016 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 SUPERFAMILY SSF46955 5 114 4.03E-26 T 23-04-2016 IPR009061 Putative DNA-binding domain SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 Pfam PF13411 MerR HTH family regulatory protein 5 73 9.7E-22 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 SMART SM00422 5 74 2.0E-24 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 3.5E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 3.5E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 3.5E-9 T 23-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 SPYM18_RS08305 603bcf25abf9fc4739cd0fc8065b19ae 245 Gene3D G3DSA:1.10.1660.10 2 59 2.8E-24 T 23-04-2016 SPYM18_RS03170 c941a4b950b622817c05b03ba2a1f762 137 TIGRFAM TIGR01671 phage_TIGR01671: phage conserved hypothetical protein TIGR01671 2 134 6.4E-55 T 23-04-2016 IPR010024 Conserved hypothetical protein CHP1671 SPYM18_RS03170 c941a4b950b622817c05b03ba2a1f762 137 Pfam PF09643 YopX protein 4 133 6.7E-26 T 23-04-2016 IPR019096 YopX protein SPYM18_RS03170 c941a4b950b622817c05b03ba2a1f762 137 Gene3D G3DSA:2.30.30.290 63 136 8.3E-20 T 23-04-2016 IPR023385 YopX-like domain, beta barrel type SPYM18_RS03170 c941a4b950b622817c05b03ba2a1f762 137 SUPERFAMILY SSF159006 1 136 1.44E-32 T 23-04-2016 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 SUPERFAMILY SSF53383 8 417 4.75E-170 T 23-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 23-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 Gene3D G3DSA:3.40.640.10 37 284 1.1E-104 T 23-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 Gene3D G3DSA:3.90.1150.10 285 417 5.9E-45 T 23-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 417 51.195 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 PIRSF PIRSF000412 1 418 2.9E-160 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 Pfam PF00464 Serine hydroxymethyltransferase 8 386 8.1E-168 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 SPYM18_RS04775 38debdc5bfb429750016a35a0b822a7b 418 PANTHER PTHR11680 8 416 9.7E-230 T 23-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 SPYM18_RS03085 a5412e621a2d39535af42c27cc848f20 62 SUPERFAMILY SSF47413 4 61 6.76E-12 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03085 a5412e621a2d39535af42c27cc848f20 62 Pfam PF01381 Helix-turn-helix 5 59 7.7E-12 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS03085 a5412e621a2d39535af42c27cc848f20 62 Gene3D G3DSA:1.10.260.40 5 61 3.7E-13 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03085 a5412e621a2d39535af42c27cc848f20 62 SMART SM00530 4 59 1.2E-9 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS06875 02d880218d1e5d617907eb965ebafb5e 574 PANTHER PTHR34220 273 571 9.0E-52 T 23-04-2016 SPYM18_RS06875 02d880218d1e5d617907eb965ebafb5e 574 SUPERFAMILY SSF55874 433 570 3.67E-11 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06875 02d880218d1e5d617907eb965ebafb5e 574 Gene3D G3DSA:3.30.565.10 422 571 2.1E-12 T 23-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain SPYM18_RS06875 02d880218d1e5d617907eb965ebafb5e 574 SMART SM00304 306 359 6.9E-4 T 23-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 SPYM18_RS06875 02d880218d1e5d617907eb965ebafb5e 574 Pfam PF06580 Histidine kinase 371 449 3.2E-24 T 23-04-2016 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 SPYM18_RS02085 6b4ae586152df6a561de0294b700fbdf 337 PANTHER PTHR23409 27 337 2.3E-54 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 SPYM18_RS02085 6b4ae586152df6a561de0294b700fbdf 337 Gene3D G3DSA:1.10.620.20 21 293 7.9E-77 T 23-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 SPYM18_RS02085 6b4ae586152df6a561de0294b700fbdf 337 SUPERFAMILY SSF47240 22 337 4.87E-90 T 23-04-2016 IPR009078 Ferritin-like superfamily SPYM18_RS02085 6b4ae586152df6a561de0294b700fbdf 337 Pfam PF00268 Ribonucleotide reductase, small chain 27 292 1.7E-70 T 23-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 SPYM18_RS02085 6b4ae586152df6a561de0294b700fbdf 337 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 25 337 2.6E-124 T 23-04-2016 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 SPYM18_RS07655 14b163c47f5f6c378de93a6eb00d38c6 125 SMART SM01022 8 101 1.0E-7 T 23-04-2016 IPR007374 ASCH domain SPYM18_RS07655 14b163c47f5f6c378de93a6eb00d38c6 125 Pfam PF04266 ASCH domain 9 97 1.7E-5 T 23-04-2016 IPR007374 ASCH domain SPYM18_RS07655 14b163c47f5f6c378de93a6eb00d38c6 125 Gene3D G3DSA:2.30.130.30 6 110 7.2E-13 T 23-04-2016 SPYM18_RS07655 14b163c47f5f6c378de93a6eb00d38c6 125 SUPERFAMILY SSF88697 5 112 2.82E-19 T 23-04-2016 IPR015947 PUA-like domain SPYM18_RS06480 30f0215ec0ba7a9ea5f8ed7b21b5bca0 172 Pfam PF08797 HIRAN domain 62 125 3.1E-10 T 23-04-2016 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 SPYM18_RS06480 30f0215ec0ba7a9ea5f8ed7b21b5bca0 172 SMART SM00910 39 140 2.9E-12 T 23-04-2016 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 SPYM18_RS00670 901d5a440bc5b200e7235215f0f848dd 144 PIRSF PIRSF031611 1 144 1.0E-56 T 23-04-2016 IPR016977 Competence operon G, ComGF SPYM18_RS00670 901d5a440bc5b200e7235215f0f848dd 144 Pfam PF15980 Putative Competence protein ComGF 39 135 9.5E-22 T 23-04-2016 IPR016977 Competence operon G, ComGF SPYM18_RS02300 f0303ebce8dd6aed7dfa52b9d6509e80 75 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 6 38 2.8E-7 T 23-04-2016 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 SUPERFAMILY SSF51306 152 272 5.62E-25 T 23-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 Pfam PF01381 Helix-turn-helix 7 67 5.9E-10 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 SUPERFAMILY SSF47413 2 73 1.85E-11 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 SMART SM00530 6 68 9.2E-11 T 23-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 Gene3D G3DSA:2.10.109.10 157 273 3.0E-22 T 23-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 Gene3D G3DSA:1.10.260.40 3 97 2.0E-16 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS05670 3ec9c5bf4a98a18205ab9207a20c3bd2 274 Pfam PF00717 Peptidase S24-like 190 257 6.7E-15 T 23-04-2016 IPR019759 Peptidase S24/S26A/S26B SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 23-04-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 Pfam PF02132 RecR protein 39 78 3.3E-16 T 23-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 PANTHER PTHR30446 1 198 4.9E-109 T 23-04-2016 SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 TIGRFAM TIGR00615 recR: recombination protein RecR 3 196 1.1E-81 T 23-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 100.477 T 23-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 Pfam PF13662 Toprim domain 81 171 4.8E-23 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 PANTHER PTHR30446:SF0 1 198 4.9E-109 T 23-04-2016 SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 SUPERFAMILY SSF111304 2 198 2.48E-73 T 23-04-2016 IPR023627 Recombination protein RecR SPYM18_RS06180 4b0a5aab280930ab99b6d39faa5438e0 198 SMART SM00493 80 165 5.4E-13 T 23-04-2016 IPR006171 Toprim domain SPYM18_RS01055 f148f412aa9d8797d7a7a31311f82d1c 502 Pfam PF05043 Mga helix-turn-helix domain 73 156 2.6E-17 T 23-04-2016 IPR007737 Mga helix-turn-helix domain SPYM18_RS01055 f148f412aa9d8797d7a7a31311f82d1c 502 Pfam PF08270 M protein trans-acting positive regulator (MGA) PRD domain 171 383 7.8E-69 T 23-04-2016 IPR013236 M protein trans-acting positive regulator (MGA), PRD domain SPYM18_RS01055 f148f412aa9d8797d7a7a31311f82d1c 502 Pfam PF08280 M protein trans-acting positive regulator (MGA) HTH domain 7 64 4.1E-14 T 23-04-2016 IPR013199 M protein trans-acting positive regulator (MGA) HTH domain SPYM18_RS08605 6972d7645cb1d4382c9c6593df2b3a6e 95 Gene3D G3DSA:1.20.120.230 11 88 7.2E-4 T 23-04-2016 SPYM18_RS06430 67a6d05028985c0b91a5f870e2fc8b23 309 Pfam PF03837 RecT family 32 221 3.6E-52 T 23-04-2016 IPR018330 RecT family GO:0003677|GO:0006259 SPYM18_RS06430 67a6d05028985c0b91a5f870e2fc8b23 309 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 9 213 5.8E-61 T 23-04-2016 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 SPYM18_RS02565 410671ac44d9b8b7629327a560b728e9 331 Pfam PF11311 Protein of unknown function (DUF3114) 38 302 2.8E-103 T 23-04-2016 IPR021462 Protein of unknown function DUF3114 SPYM18_RS01480 648dce988be615cfd1c88758599ece30 458 Pfam PF02386 Cation transport protein 37 441 7.7E-60 T 23-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 SPYM18_RS01480 648dce988be615cfd1c88758599ece30 458 PANTHER PTHR32024:SF1 13 458 6.9E-130 T 23-04-2016 SPYM18_RS01480 648dce988be615cfd1c88758599ece30 458 PANTHER PTHR32024 13 458 6.9E-130 T 23-04-2016 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 SUPERFAMILY SSF53137 12 127 6.54E-49 T 23-04-2016 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 Gene3D G3DSA:3.30.420.80 5 127 7.8E-56 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 3.2E-58 T 23-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 33.455 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 PIRSF PIRSF002131 2 127 1.1E-51 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 Pfam PF00411 Ribosomal protein S11 17 126 1.8E-51 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 23-04-2016 IPR018102 Ribosomal S11, conserved site SPYM18_RS00490 1991356a13c0b6ae7fb6748ea8c3eb74 127 PANTHER PTHR11759 8 127 1.7E-70 T 23-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 SPYM18_RS03130 d229da426285f72f56ca7e0f831b8c64 329 Pfam PF03837 RecT family 32 241 9.1E-48 T 23-04-2016 IPR018330 RecT family GO:0003677|GO:0006259 SPYM18_RS03130 d229da426285f72f56ca7e0f831b8c64 329 TIGRFAM TIGR00616 rect: recombinase, phage RecT family 8 234 3.7E-53 T 23-04-2016 IPR004590 DNA single-strand annealing protein RecT GO:0003677|GO:0006259 SPYM18_RS02290 67b238cfc05d353ce33831c10864d912 74 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 6 61 9.2E-7 T 23-04-2016 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 PANTHER PTHR10342 239 600 1.1E-97 T 23-04-2016 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 PANTHER PTHR10342 645 671 1.1E-97 T 23-04-2016 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 Gene3D G3DSA:3.40.720.10 267 584 5.8E-34 T 23-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 PIRSF PIRSF005091 7 661 4.1E-172 T 23-04-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 Pfam PF00884 Sulfatase 267 571 3.6E-30 T 23-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 PANTHER PTHR10342:SF214 239 600 1.1E-97 T 23-04-2016 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 PANTHER PTHR10342:SF214 645 671 1.1E-97 T 23-04-2016 SPYM18_RS03740 1aff2e8777e9f32f8efe6227c11ad9af 736 SUPERFAMILY SSF53649 265 676 1.74E-69 T 23-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 PANTHER PTHR10000:SF27 1 261 1.0E-58 T 23-04-2016 SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 Gene3D G3DSA:3.40.50.1000 181 263 1.4E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 Gene3D G3DSA:3.40.50.1000 1 73 1.4E-39 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 SUPERFAMILY SSF56784 1 264 2.18E-55 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 Gene3D G3DSA:3.30.1240.10 83 180 2.1E-26 T 23-04-2016 SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 261 2.5E-59 T 23-04-2016 IPR023214 HAD-like domain SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 233 5.3E-27 T 23-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 PANTHER PTHR10000 1 261 1.0E-58 T 23-04-2016 SPYM18_RS02730 a259d95a2c4c680223f2b8571eb1aa4d 265 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 261 7.8E-45 T 23-04-2016 IPR000150 Cof protein GO:0016787 SPYM18_RS08355 26bb6995d965a3e6ca289d62a112e792 141 SUPERFAMILY SSF55729 9 135 7.09E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08355 26bb6995d965a3e6ca289d62a112e792 141 Gene3D G3DSA:3.40.630.30 4 136 7.4E-25 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS08355 26bb6995d965a3e6ca289d62a112e792 141 PANTHER PTHR23091 5 136 1.8E-20 T 23-04-2016 SPYM18_RS08355 26bb6995d965a3e6ca289d62a112e792 141 Pfam PF13508 Acetyltransferase (GNAT) domain 38 114 1.6E-12 T 23-04-2016 IPR000182 GNAT domain GO:0008080 SPYM18_RS08355 26bb6995d965a3e6ca289d62a112e792 141 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 8 133 1.8E-30 T 23-04-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 SPYM18_RS07660 195125f090331f3eb679c0020c3197e5 89 SUPERFAMILY SSF55729 2 87 4.4E-7 T 23-04-2016 IPR016181 Acyl-CoA N-acyltransferase SPYM18_RS02320 0ab6e671098456d262346b25af82138d 59 Gene3D G3DSA:3.30.420.10 1 50 1.6E-5 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02320 0ab6e671098456d262346b25af82138d 59 Pfam PF13333 Integrase core domain 2 55 2.5E-15 T 23-04-2016 IPR001584 Integrase, catalytic core GO:0015074 SPYM18_RS02320 0ab6e671098456d262346b25af82138d 59 SUPERFAMILY SSF53098 1 53 6.83E-7 T 23-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 SPYM18_RS02420 79a517ef88f09e59fd39d89dc92d5aeb 78 Pfam PF03840 Preprotein translocase SecG subunit 4 75 5.0E-16 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPYM18_RS02420 79a517ef88f09e59fd39d89dc92d5aeb 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 9.7E-19 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPYM18_RS02420 79a517ef88f09e59fd39d89dc92d5aeb 78 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 6.4E-6 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPYM18_RS02420 79a517ef88f09e59fd39d89dc92d5aeb 78 PRINTS PR01651 Protein-export SecG membrane protein signature 56 78 6.4E-6 T 23-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 SPYM18_RS05530 0d27c749dc7429b452187ef4540afda2 429 PANTHER PTHR39184 1 416 1.3E-57 T 23-04-2016 SPYM18_RS05530 0d27c749dc7429b452187ef4540afda2 429 PANTHER PTHR39184:SF1 1 416 1.3E-57 T 23-04-2016 SPYM18_RS05530 0d27c749dc7429b452187ef4540afda2 429 TIGRFAM TIGR01547 phage_term_2: phage terminase, large subunit, PBSX family 29 410 3.5E-50 T 23-04-2016 IPR006437 Bacteriophage terminase, large subunit GO:0006323 SPYM18_RS05530 0d27c749dc7429b452187ef4540afda2 429 Pfam PF04466 Phage terminase large subunit 27 408 7.4E-144 T 23-04-2016 IPR006437 Bacteriophage terminase, large subunit GO:0006323 SPYM18_RS00615 c710e9e763ddb4163853e8d623f631ff 127 Pfam PF01230 HIT domain 14 101 7.4E-11 T 23-04-2016 IPR001310 Histidine triad (HIT) protein SPYM18_RS00615 c710e9e763ddb4163853e8d623f631ff 127 SUPERFAMILY SSF54197 2 112 2.63E-24 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 SPYM18_RS00615 c710e9e763ddb4163853e8d623f631ff 127 Gene3D G3DSA:3.30.428.10 3 112 2.9E-20 T 23-04-2016 IPR011146 HIT-like domain GO:0003824 SPYM18_RS00665 e2e93b71f3193ac8c3215a423fccfe47 94 Pfam PF11773 Type II secretory pathway pseudopilin 12 93 3.6E-32 T 23-04-2016 IPR021749 Type II secretory pathway pseudopilin SPYM18_RS04460 9cdd675203fdae5f52313a50fcca1a62 339 PANTHER PTHR30106:SF1 6 339 6.2E-146 T 23-04-2016 SPYM18_RS04460 9cdd675203fdae5f52313a50fcca1a62 339 PANTHER PTHR30106 6 339 6.2E-146 T 23-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SPYM18_RS04460 9cdd675203fdae5f52313a50fcca1a62 339 Pfam PF03601 Conserved hypothetical protein 698 9 317 1.0E-100 T 23-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 SPYM18_RS08845 688de7cef7a3f9277a9479d8b05f1032 156 Pfam PF11217 Protein of unknown function (DUF3013) 1 155 3.4E-62 T 23-04-2016 IPR021380 Protein of unknown function DUF3013 SPYM18_RS05585 17de5a606e61b111ffccac31bfa20360 289 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 6 168 1.5E-7 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SPYM18_RS05585 17de5a606e61b111ffccac31bfa20360 289 SMART SM00942 221 284 9.8E-13 T 23-04-2016 IPR014820 Primase, C-terminal 1 SPYM18_RS05585 17de5a606e61b111ffccac31bfa20360 289 SUPERFAMILY SSF56747 99 170 6.54E-17 T 23-04-2016 SPYM18_RS05585 17de5a606e61b111ffccac31bfa20360 289 SUPERFAMILY SSF56747 3 67 6.54E-17 T 23-04-2016 SPYM18_RS05585 17de5a606e61b111ffccac31bfa20360 289 SMART SM00943 6 199 9.7E-22 T 23-04-2016 IPR015330 DNA primase/polymerase, bifunctional, N-terminal SPYM18_RS07055 d2f08a6ffa93534b48857ea8e7353956 230 PIRSF PIRSF031509 1 230 1.2E-83 T 23-04-2016 IPR016975 Cell wall-active antibiotic response protein GO:0016021 SPYM18_RS07055 d2f08a6ffa93534b48857ea8e7353956 230 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 115 227 1.9E-35 T 23-04-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF SPYM18_RS09005 78872c78538bdfca134caa54812ef899 101 Pfam PF13734 Spi protease inhibitor 7 97 7.5E-17 T 23-04-2016 IPR025896 Spi protease inhibitor SPYM18_RS09005 78872c78538bdfca134caa54812ef899 101 SUPERFAMILY SSF54001 5 100 3.43E-18 T 23-04-2016 SPYM18_RS05625 ace6ef518cd3381300f4dd398457337b 98 Gene3D G3DSA:1.10.10.10 40 90 1.0E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS05625 ace6ef518cd3381300f4dd398457337b 98 SUPERFAMILY SSF46955 39 90 8.55E-9 T 23-04-2016 IPR009061 Putative DNA-binding domain SPYM18_RS04710 67cec4e70ecfc8055a52e2b58b6f7dce 229 Gene3D G3DSA:3.30.450.20 139 218 5.5E-7 T 23-04-2016 SPYM18_RS03700 8466741b584b6a674014a4cfa05e8792 498 Pfam PF09913 Predicted membrane protein (DUF2142) 72 454 7.2E-104 T 23-04-2016 IPR018674 Protein of unknown function DUF2142, membrane SPYM18_RS02705 f04af81e90f872333a9c0e7ec639e31c 66 Gene3D G3DSA:3.30.930.10 8 55 4.6E-6 T 23-04-2016 SPYM18_RS04745 10109355d39e3619d107ac30c262e57c 61 SUPERFAMILY SSF55331 2 57 3.4E-17 T 23-04-2016 IPR014347 Tautomerase/MIF superfamily SPYM18_RS04745 10109355d39e3619d107ac30c262e57c 61 Pfam PF01361 Tautomerase enzyme 2 59 1.0E-23 T 23-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 SPYM18_RS04745 10109355d39e3619d107ac30c262e57c 61 PANTHER PTHR35530 1 57 3.7E-16 T 23-04-2016 SPYM18_RS04745 10109355d39e3619d107ac30c262e57c 61 Gene3D G3DSA:3.30.429.20 1 58 6.8E-22 T 23-04-2016 SPYM18_RS06645 0a43e696d96d50ab751c362c8b99b233 83 Pfam PF11364 Protein of unknown function (DUF3165) 1 80 1.2E-38 T 23-04-2016 IPR021506 Protein of unknown function DUF3165 SPYM18_RS01760 c64db9a12879d6ce59ecf1ef7aaf61a9 256 Pfam PF05709 Phage tail protein 39 256 1.2E-29 T 23-04-2016 IPR008841 Siphovirus-type tail component SPYM18_RS01760 c64db9a12879d6ce59ecf1ef7aaf61a9 256 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 34 147 2.8E-9 T 23-04-2016 IPR006520 Streptococcus phage 7201, Orf34, N-terminal SPYM18_RS03225 981745da28f268138f63a3b91de86dd7 155 TIGRFAM TIGR01558 sm_term_P27: putative phage terminase, small subunit, P27 family 41 145 5.0E-21 T 23-04-2016 IPR006448 Putative phage terminase, small subunit, P27 family SPYM18_RS03225 981745da28f268138f63a3b91de86dd7 155 Pfam PF05119 Phage terminase, small subunit 49 143 7.6E-20 T 23-04-2016 IPR006448 Putative phage terminase, small subunit, P27 family SPYM18_RS03550 fd123aeab78a1f94a9945c95fb43a193 85 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 14 84 2.0E-30 T 23-04-2016 IPR009526 Protein of unknown function DUF1146 SPYM18_RS03550 fd123aeab78a1f94a9945c95fb43a193 85 Pfam PF06612 Protein of unknown function (DUF1146) 21 68 2.3E-13 T 23-04-2016 IPR009526 Protein of unknown function DUF1146 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 SUPERFAMILY SSF161098 18 307 6.28E-54 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 PANTHER PTHR32243 271 308 1.3E-112 T 23-04-2016 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 PANTHER PTHR32243 10 254 1.3E-112 T 23-04-2016 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 PANTHER PTHR32243:SF5 271 308 1.3E-112 T 23-04-2016 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 PANTHER PTHR32243:SF5 10 254 1.3E-112 T 23-04-2016 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 Gene3D G3DSA:1.10.3720.10 17 295 4.7E-47 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS06890 d3a9aa2568725653823b426336921db6 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 298 3.1E-9 T 23-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 SPYM18_RS05685 7a763cd0084f0856a55cddf0e67d0339 206 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 47 204 2.9E-79 T 23-04-2016 IPR024418 Protein of unknown function DUF3862 SPYM18_RS01250 4d613e4467c1f6b98e5c7fd39c6c1741 873 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 246 630 2.0E-100 T 23-04-2016 IPR027607 SEC10/PgrA surface exclusion domain SPYM18_RS05220 4da0dc9464612565c0b15d234c57d190 878 PANTHER PTHR30489 1 474 2.3E-45 T 23-04-2016 SPYM18_RS05220 4da0dc9464612565c0b15d234c57d190 878 PANTHER PTHR30489:SF11 1 474 2.3E-45 T 23-04-2016 SPYM18_RS05220 4da0dc9464612565c0b15d234c57d190 878 Pfam PF02687 FtsX-like permease family 752 868 8.2E-15 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS05220 4da0dc9464612565c0b15d234c57d190 878 Pfam PF02687 FtsX-like permease family 350 466 2.4E-13 T 23-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 SPYM18_RS02445 86b6f01c7093f59475a56908f44ca3cc 308 Pfam PF06166 Protein of unknown function (DUF979) 10 307 3.5E-113 T 23-04-2016 IPR009323 Protein of unknown function DUF979 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 Pfam PF00232 Glycosyl hydrolase family 1 8 464 9.0E-124 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PANTHER PTHR10353 7 465 4.8E-253 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 SUPERFAMILY SSF51445 7 465 2.99E-156 T 23-04-2016 IPR017853 Glycoside hydrolase superfamily SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 388 399 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 293 307 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 409 426 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 365 373 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PRINTS PR00131 Glycosyl hydrolase family 1 signature 433 445 1.3E-15 T 23-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 Gene3D G3DSA:3.20.20.80 8 465 7.8E-138 T 23-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 SPYM18_RS05805 d5328be457d7528b9ceb2a86723cb742 466 PANTHER PTHR10353:SF73 7 465 4.8E-253 T 23-04-2016 SPYM18_RS07800 78e762bc48195b18aa843c5929c55a67 128 Pfam PF06114 Domain of unknown function (DUF955) 11 85 1.7E-9 T 23-04-2016 IPR010359 HTH domain, IrrE-type SPYM18_RS09275 3e35c80d1d810806bfebb4507db4f56f 519 Pfam PF09852 Predicted membrane protein (DUF2079) 91 360 1.4E-6 T 23-04-2016 IPR018650 Sulfolobus virus STSV1, Orf64 SPYM18_RS09275 3e35c80d1d810806bfebb4507db4f56f 519 PIRSF PIRSF031639 1 519 3.8E-232 T 23-04-2016 IPR016978 Putative competence-induced protein Ccs4 SPYM18_RS07570 c603b3604f57da8e85f1892dd89c07d8 238 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 7 128 1.3E-7 T 23-04-2016 IPR006520 Streptococcus phage 7201, Orf34, N-terminal SPYM18_RS07570 c603b3604f57da8e85f1892dd89c07d8 238 Pfam PF05709 Phage tail protein 29 229 2.6E-9 T 23-04-2016 IPR008841 Siphovirus-type tail component SPYM18_RS07575 7a13fcad4f542a86f2221fb75b16eb13 1086 TIGRFAM TIGR02675 tape_meas_nterm: tape measure domain 135 213 9.2E-25 T 23-04-2016 IPR013491 Caudovirus, tape measure, N-terminal SPYM18_RS07575 7a13fcad4f542a86f2221fb75b16eb13 1086 SUPERFAMILY SSF58113 879 933 5.1E-5 T 23-04-2016 SPYM18_RS07575 7a13fcad4f542a86f2221fb75b16eb13 1086 SUPERFAMILY SSF58113 673 775 5.1E-5 T 23-04-2016 SPYM18_RS00360 ef7f0898e10671826264d07a9498c265 429 TIGRFAM TIGR00797 matE: MATE efflux family protein 14 402 6.0E-61 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 SPYM18_RS00360 ef7f0898e10671826264d07a9498c265 429 PANTHER PTHR11206 6 412 7.0E-59 T 23-04-2016 SPYM18_RS00360 ef7f0898e10671826264d07a9498c265 429 Pfam PF01554 MatE 14 173 1.3E-24 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 SPYM18_RS00360 ef7f0898e10671826264d07a9498c265 429 Pfam PF01554 MatE 228 389 5.6E-25 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 SPYM18_RS00360 ef7f0898e10671826264d07a9498c265 429 PIRSF PIRSF006603 5 426 2.7E-72 T 23-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 SPYM18_RS05005 0b204d445c680ff8b09f42939b7290a0 185 Pfam PF07155 ECF-type riboflavin transporter, S component 9 168 2.5E-15 T 23-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PANTHER PTHR33308 17 165 3.3E-21 T 23-04-2016 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PANTHER PTHR33308:SF3 17 165 3.3E-21 T 23-04-2016 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 SMART SM00047 2 145 2.5E-25 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 15 140 3.6E-19 T 23-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PRINTS PR01002 Flagellar protein FlgJ signature 122 140 3.4E-9 T 23-04-2016 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PRINTS PR01002 Flagellar protein FlgJ signature 102 121 3.4E-9 T 23-04-2016 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PRINTS PR01002 Flagellar protein FlgJ signature 80 101 3.4E-9 T 23-04-2016 SPYM18_RS05390 2777bbeb2628b31aa1dcee878124621c 185 PRINTS PR01002 Flagellar protein FlgJ signature 35 56 3.4E-9 T 23-04-2016 SPYM18_RS06810 55d7a1b1b07950054875dc800a7f5582 187 SUPERFAMILY SSF52540 1 145 3.35E-10 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS06810 55d7a1b1b07950054875dc800a7f5582 187 Gene3D G3DSA:3.40.50.300 1 182 1.8E-9 T 23-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase SPYM18_RS07735 dd3d5baadc1be5f20b0dace151b01867 224 Pfam PF04404 ERF superfamily 11 148 4.2E-34 T 23-04-2016 IPR007499 Essential recombination function protein SPYM18_RS02350 30c2766c6de3e9d40f32598d4fed96d0 75 TIGRFAM TIGR01847 bacteriocin_sig: bacteriocin-type signal sequence 9 23 0.0047 T 23-04-2016 IPR010133 Bacteriocin-type signal sequence SPYM18_RS02350 30c2766c6de3e9d40f32598d4fed96d0 75 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 7 75 8.2E-12 T 23-04-2016 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 SPYM18_RS08695 f595555249089cf68df62e15b67a2a28 459 PANTHER PTHR33843:SF4 1 457 1.0E-223 T 23-04-2016 SPYM18_RS08695 f595555249089cf68df62e15b67a2a28 459 PANTHER PTHR33843 1 457 1.0E-223 T 23-04-2016 SPYM18_RS08695 f595555249089cf68df62e15b67a2a28 459 Pfam PF03611 PTS system sugar-specific permease component 10 408 4.7E-129 T 23-04-2016 IPR004703 Phosphotransferase system, sugar-specific permease component GO:0009401|GO:0016021 SPYM18_RS09450 df2f6c8d5d63fb4b622e69000959a594 195 Pfam PF08006 Protein of unknown function (DUF1700) 1 187 9.6E-20 T 23-04-2016 IPR012963 Protein of unknown function DUF1700 SPYM18_RS05430 ffaff96802a1d1ec2c7b7a6a21ea3a6b 259 Pfam PF05709 Phage tail protein 41 259 5.2E-36 T 23-04-2016 IPR008841 Siphovirus-type tail component SPYM18_RS05430 ffaff96802a1d1ec2c7b7a6a21ea3a6b 259 TIGRFAM TIGR01633 phi3626_gp14_N: putative phage tail component, N-terminal domain 32 149 2.3E-18 T 23-04-2016 IPR006520 Streptococcus phage 7201, Orf34, N-terminal SPYM18_RS03710 8c209a38b0795b01fe5afbbcade14ebe 162 ProDom PD091538 PORE-FORMING FORMING PORE PEPTIDE EBSA PEPTIDE GBS1458 SMU.692 SAG1388 7 129 7.0E-66 T 23-04-2016 IPR020215 Pore-forming protein, EbsA SPYM18_RS02310 fb5497b04e51da52dc3a789946204058 117 Pfam PF13276 HTH-like domain 32 83 1.5E-17 T 23-04-2016 IPR025948 HTH-like domain SPYM18_RS02310 fb5497b04e51da52dc3a789946204058 117 PANTHER PTHR32552 8 116 6.4E-13 T 23-04-2016 SPYM18_RS02310 fb5497b04e51da52dc3a789946204058 117 PANTHER PTHR32552:SF28 8 116 6.4E-13 T 23-04-2016 SPYM18_RS05545 fc1616849b5bfbc1ce548342e31e0cef 85 Pfam PF07852 Protein of unknown function (DUF1642) 3 84 9.7E-21 T 23-04-2016 IPR012865 Protein of unknown function DUF1642 SPYM18_RS06035 8f7c6eb4a76ba2c503f4ff3e5ac7d107 231 Pfam PF02517 CAAX protease self-immunity 131 218 6.9E-18 T 23-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 SPYM18_RS03200 597b11ff1a8a08378afae44892965d25 145 Pfam PF07374 Protein of unknown function (DUF1492) 37 134 6.2E-7 T 23-04-2016 IPR010861 Protein of unknown function DUF1492 SPYM18_RS01850 5e8075dfdf1df925cb1087559305755f 92 Gene3D G3DSA:3.30.70.100 1 90 5.3E-25 T 23-04-2016 SPYM18_RS01850 5e8075dfdf1df925cb1087559305755f 92 PANTHER PTHR10029 4 90 1.8E-15 T 23-04-2016 SPYM18_RS01850 5e8075dfdf1df925cb1087559305755f 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 23-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPYM18_RS01850 5e8075dfdf1df925cb1087559305755f 92 Pfam PF00708 Acylphosphatase 1 90 4.3E-23 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPYM18_RS01850 5e8075dfdf1df925cb1087559305755f 92 SUPERFAMILY SSF54975 2 90 1.77E-21 T 23-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 SPYM18_RS03455 d9660f7b19051580cb158d58c89d1f78 352 TIGRFAM TIGR03603 cyclo_dehy_ocin: thiazole/oxazole-forming peptide maturase, SagC family component 25 351 6.7E-140 T 23-04-2016 IPR019892 Thiazole/oxazole-forming peptide maturase, SagC family component SPYM18_RS04185 1706f732665070aaec72f3a067d9b732 76 Pfam PF11184 Protein of unknown function (DUF2969) 1 75 2.9E-26 T 23-04-2016 IPR021351 Protein of unknown function DUF2969 SPYM18_RS07295 4078b3a28c4c4a64c398299756b5f12f 130 Gene3D G3DSA:3.10.450.40 62 121 1.8E-4 T 23-04-2016 SPYM18_RS07295 4078b3a28c4c4a64c398299756b5f12f 130 Pfam PF03413 Peptidase propeptide and YPEB domain 61 123 2.7E-12 T 23-04-2016 IPR025711 PepSY domain SPYM18_RS02770 641076f1adc9afdf20ed23c084f07c68 300 PANTHER PTHR34184:SF1 1 300 2.4E-108 T 23-04-2016 SPYM18_RS02770 641076f1adc9afdf20ed23c084f07c68 300 Pfam PF03773 Predicted permease 13 297 3.1E-66 T 23-04-2016 IPR005524 Predicted permease DUF318 SPYM18_RS02770 641076f1adc9afdf20ed23c084f07c68 300 PANTHER PTHR34184 1 300 2.4E-108 T 23-04-2016 SPYM18_RS05620 482d2af46181d7ceba15a39bae384e4f 109 Gene3D G3DSA:1.10.10.10 13 106 1.5E-4 T 23-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain SPYM18_RS01035 67267e3af4f521ba898c9ab4b2760524 410 SMART SM00460 199 261 0.0079 T 23-04-2016 IPR002931 Transglutaminase-like SPYM18_RS01035 67267e3af4f521ba898c9ab4b2760524 410 Pfam PF01841 Transglutaminase-like superfamily 153 258 2.8E-7 T 23-04-2016 IPR002931 Transglutaminase-like SPYM18_RS01035 67267e3af4f521ba898c9ab4b2760524 410 SUPERFAMILY SSF54001 197 296 8.54E-14 T 23-04-2016 SPYM18_RS07545 255ec51997af3413f9b4dfb45e583f10 205 Pfam PF07104 Protein of unknown function (DUF1366) 5 95 1.3E-8 T 23-04-2016 IPR009796 Protein of unknown function DUF1366 SPYM18_RS05595 5c920fa2d6e6354ed856f189bfc9f2b8 160 Pfam PF05037 Protein of unknown function (DUF669) 4 134 6.1E-18 T 23-04-2016 IPR007731 Protein of unknown function DUF669 SPYM18_RS00835 700a5cf585410f1488f1be5c266e22eb 666 Pfam PF01496 V-type ATPase 116kDa subunit family 563 649 5.1E-8 T 23-04-2016 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 SPYM18_RS00835 700a5cf585410f1488f1be5c266e22eb 666 Pfam PF01496 V-type ATPase 116kDa subunit family 257 412 2.3E-9 T 23-04-2016 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 SPYM18_RS03305 9d7759dae264cbda5675115621c298ce 658 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 10 315 1.2E-19 T 23-04-2016 IPR007119 Phage minor structural protein, N-terminal domain SPYM18_RS04875 4c9c1954de17238b0f01142b54d4eba1 104 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 9 81 5.1E-5 T 23-04-2016 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0071436 KEGG: 00620+4.1.1.3|MetaCyc: PWY-6339 SPYM18_RS08645 f928e18b21b03e03b9fd576c28d8a040 172 PANTHER PTHR34547 5 156 2.3E-40 T 23-04-2016 SPYM18_RS08645 f928e18b21b03e03b9fd576c28d8a040 172 Pfam PF05991 YacP-like NYN domain 6 165 2.8E-50 T 23-04-2016 IPR010298 Protein of unknown function DUF901 SPYM18_RS01690 b51985cecb74e2de2d6b65a506e28cd4 105 Pfam PF05119 Phage terminase, small subunit 20 80 1.0E-5 T 23-04-2016 IPR006448 Putative phage terminase, small subunit, P27 family SPYM18_RS07790 4bc84dc4c5b58c1e647654788451a679 70 Gene3D G3DSA:1.10.260.40 2 65 2.8E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS07790 4bc84dc4c5b58c1e647654788451a679 70 SUPERFAMILY SSF47413 3 59 4.74E-5 T 23-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 SPYM18_RS03160 38aa895185a43cc79380d87cc9ec1207 94 Pfam PF11753 Protein of unknwon function (DUF3310) 24 84 5.2E-19 T 23-04-2016 IPR021739 Protein of unknwon function DUF3310 SPYM18_RS02815 86bd09aa89ec37a5838ce26e95a134c4 94 Pfam PF11674 Protein of unknown function (DUF3270) 4 89 1.7E-31 T 23-04-2016 IPR021688 Protein of unknown function DUF3270 SPYM18_RS06325 dbec643c3164adb5904e67fc0a17d30c 140 Pfam PF09355 Phage protein Gp19/Gp15/Gp42 13 128 3.1E-50 T 23-04-2016 IPR018963 Mycobacteriophage D29, Gp19 SPYM18_RS01755 b4b718388ad96e8e803355c20062c121 1366 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 157 521 9.6E-92 T 23-04-2016 IPR010090 Phage tail tape measure protein SPYM18_RS01755 b4b718388ad96e8e803355c20062c121 1366 Pfam PF10145 Phage-related minor tail protein 206 396 2.9E-17 T 23-04-2016 IPR010090 Phage tail tape measure protein SPYM18_RS08260 1b59c7db9e3176d046a05e6f68635247 298 Pfam PF01925 Sulfite exporter TauE/SafE 10 151 7.8E-8 T 23-04-2016 IPR002781 Transmembrane protein TauE-like GO:0016021 SPYM18_RS05255 68cc5dc638444af57e2cf8b6575b38c1 62 Pfam PF10031 Small integral membrane protein (DUF2273) 3 49 4.3E-14 T 23-04-2016 IPR018730 Protein of unknown function DUF2273 SPYM18_RS06270 a7cb26eb2b5998e17a482a26d25b6a3e 657 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 22 338 4.3E-42 T 23-04-2016 IPR007119 Phage minor structural protein, N-terminal domain SPYM18_RS05445 e697fa7ae6cd29616e99144d91be88f3 119 Pfam PF12363 Phage tail assembly chaperone protein, TAC 2 108 1.2E-33 T 23-04-2016 IPR024410 Phage tail assembly chaperone protein, TAC SPYM18_RS07580 b277eb893cc9705bb168d2a7427e3da7 193 Pfam PF06854 Bacteriophage Gp15 protein 3 183 4.9E-48 T 23-04-2016 IPR009660 Bacteriophage A500, Gp15 SPYM18_RS08990 63a95b938ce764622af9735484605f15 98 Pfam PF14131 Domain of unknown function (DUF4298) 9 89 7.5E-23 T 23-04-2016 IPR025384 Protein of unknown function DUF4298 SPYM18_RS05215 91158bd396dc2cb1b41e3519d091805c 198 SUPERFAMILY SSF116734 14 168 5.23E-19 T 23-04-2016 SPYM18_RS05215 91158bd396dc2cb1b41e3519d091805c 198 PIRSF PIRSF036177 1 198 2.5E-88 T 23-04-2016 IPR017043 Type I restriction-modification system, specificity subunit, predicted SPYM18_RS02195 57b83217ebbd48f9700f4d1f9470a460 117 Pfam PF11877 Protein of unknown function (DUF3397) 6 114 6.2E-25 T 23-04-2016 IPR024515 Protein of unknown function DUF3397 SPYM18_RS06255 9272c2438c2f9d732695776a07869a9a 143 Pfam PF07761 Protein of unknown function (DUF1617) 1 143 2.4E-92 T 23-04-2016 IPR011675 Protein of unknown function DUF1617 SPYM18_RS08210 8866e8cfeefd48d13b1a4937ea9d196d 181 Pfam PF02674 Colicin V production protein 2 165 2.7E-27 T 23-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 SPYM18_RS02675 f75dc2ca9d9ff3034fe9305d49b89ce0 150 Pfam PF04860 Phage portal protein 48 125 1.5E-26 T 23-04-2016 IPR006944 Bacteriophage/Gene transfer agent portal protein SPYM18_RS05540 69cbb2f3f634d23418d7f199068c58f8 146 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 3 135 8.5E-41 T 23-04-2016 IPR006524 Transcription activator, ArpU family SPYM18_RS00905 93755bec7552b63880a971d2689b18c1 118 Pfam PF16718 Immunity factor for SPN 1 118 7.1E-45 T 23-04-2016 IPR032002 Immunity factor for SPN SPYM18_RS01730 3aabc7d76b6839d8ca268c309e599c55 132 Pfam PF04883 Bacteriophage HK97-gp10, putative tail-component 12 95 2.7E-4 T 23-04-2016 IPR010064 Bacteriophage HK97-gp10, putative tail-component SPYM18_RS07565 08bacecd791bc42adc3f4bb1be93af36 659 TIGRFAM TIGR01665 put_anti_recept: phage minor structural protein, N-terminal region 10 315 1.2E-19 T 23-04-2016 IPR007119 Phage minor structural protein, N-terminal domain SPYM18_RS05470 39f1f30372b85e34681d9e0fe5d54415 117 Pfam PF05135 Phage gp6-like head-tail connector protein 10 93 3.4E-7 T 23-04-2016 IPR021146 Phage gp6-like head-tail connector protein SPYM18_RS07315 c6baa5ee6713780891a59f7a6c1e2735 177 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 75 166 3.0E-31 T 23-04-2016 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 SPYM18_RS02685 42084ab6ee74eaca59a1c5ea98909a63 112 Gene3D G3DSA:1.10.3290.10 16 102 9.1E-12 T 23-04-2016 IPR003812 Fido domain