locus-tag	class	description
DZM45_RS00010	COG0592	DNA-directed DNA polymerase activity
DZM45_RS00020	COG0012	GTP binding
DZM45_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DZM45_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DZM45_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DZM45_RS00065	COG0531	amino acid
DZM45_RS00245	COG3942	CHAP domain
DZM45_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DZM45_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DZM45_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DZM45_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DZM45_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DZM45_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DZM45_RS00355	COG1454	alcohol dehydrogenase
DZM45_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
DZM45_RS00360	COG1064	alcohol dehydrogenase
DZM45_RS00365	COG0534	Mate efflux family protein
DZM45_RS00475	COG0201	protein transport
DZM45_RS00620	COG1121	(ABC) transporter
DZM45_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DZM45_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DZM45_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DZM45_RS00665	COG1459	type II secretion system
DZM45_RS00670	COG4537	Required for transformation and DNA binding
DZM45_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DZM45_RS00715	COG1363	Peptidase, m42
DZM45_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DZM45_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DZM45_RS00745	COG1428	Deoxynucleoside kinase
DZM45_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DZM45_RS00795	COG4509	Sortase family
DZM45_RS00820	COG2031	fatty acid transporter
DZM45_RS00835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DZM45_RS00850	COG0251	oxidation-reduction process
DZM45_RS00865	COG1269	ATP hydrolysis coupled proton transport
DZM45_RS00870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DZM45_RS00880	COG1527	subunit (C
DZM45_RS00885	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
DZM45_RS00920	COG1744	ABC transporter substrate-binding protein PnrA-like
DZM45_RS00965	COG0626	cystathionine gamma-synthase activity
DZM45_RS00995	COG3623	hexulose-6-phosphate isomerase
DZM45_RS01020	COG4175	Glycine betaine
DZM45_RS01020	COG3448	diguanylate cyclase activity
DZM45_RS01030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DZM45_RS01030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DZM45_RS01050	COG3969	phosphoadenosine phosphosulfate
DZM45_RS01055	COG1475	DNA binding
DZM45_RS01105	COG1268	BioY protein
DZM45_RS01110	COG1234	tRNA 3'-trailer cleavage
DZM45_RS01145	COG0457	Tetratricopeptide repeat
DZM45_RS01145	COG0705	Rhomboid family
DZM45_RS01165	COG1132	(ABC) transporter
DZM45_RS01170	COG1132	(ABC) transporter
DZM45_RS01180	COG0756	dUTP diphosphatase activity
DZM45_RS01205	COG3290	protein histidine kinase activity
DZM45_RS01230	COG1847	R3H domain protein
DZM45_RS01250	COG1175	transmembrane transport
DZM45_RS01255	COG0395	ABC-type sugar transport system, permease component
DZM45_RS01265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DZM45_RS01280	COG0084	hydrolase, TatD family'
DZM45_RS01305	COG1564	THIamine pyrophosphokinase
DZM45_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DZM45_RS01360	COG0765	amino acid transport
DZM45_RS01380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DZM45_RS01390	COG0719	Fe-S assembly protein
DZM45_RS01395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DZM45_RS01410	COG1686	Belongs to the peptidase S11 family
DZM45_RS01415	COG1686	Belongs to the peptidase S11 family
DZM45_RS01420	COG4166	transmembrane transport
DZM45_RS01425	COG0601	transmembrane transport
DZM45_RS01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DZM45_RS01435	COG0444	Belongs to the ABC transporter superfamily
DZM45_RS01490	COG0351	phosphomethylpyrimidine kinase
DZM45_RS01495	COG4720	Psort location CytoplasmicMembrane, score
DZM45_RS01505	COG0668	transmembrane transport
DZM45_RS01560	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DZM45_RS01575	COG0789	Transcriptional regulator
DZM45_RS01580	COG0174	glutamine synthetase
DZM45_RS01595	COG1214	PFAM Peptidase M22, glycoprotease
DZM45_RS01600	COG0456	acetyltransferase
DZM45_RS01620	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DZM45_RS01625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DZM45_RS01635	COG2081	HI0933 family
DZM45_RS01670	COG0789	Transcriptional regulator
DZM45_RS01695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DZM45_RS01700	COG2814	Major facilitator Superfamily
DZM45_RS01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DZM45_RS01725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DZM45_RS01730	COG1882	Formate acetyltransferase
DZM45_RS01745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DZM45_RS01750	COG0681	Belongs to the peptidase S26 family
DZM45_RS01780	COG3118	belongs to the thioredoxin family
DZM45_RS01790	COG1194	a g-specific adenine glycosylase
DZM45_RS01830	COG0006	proline dipeptidase activity
DZM45_RS01835	COG2131	deaminase
DZM45_RS01855	COG1609	Transcriptional regulator
DZM45_RS01860	COG1621	beta-fructofuranosidase activity
DZM45_RS01865	COG1263	PTS System
DZM45_RS01865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DZM45_RS01865	COG2190	(PTS) system
DZM45_RS01875	COG1940	carbohydrate kinase activity
DZM45_RS01880	COG1482	cell wall glycoprotein biosynthetic process
DZM45_RS01900	COG3942	CHAP domain
DZM45_RS01900	COG1388	LysM domain
DZM45_RS01925	COG1120	ATPase activity
DZM45_RS01930	COG1132	(ABC) transporter
DZM45_RS01935	COG1132	(ABC) transporter
DZM45_RS01950	COG1129	ABC transporter
DZM45_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DZM45_RS01975	COG0252	asparaginase activity
DZM45_RS01980	COG0561	phosphatase activity
DZM45_RS01990	COG0436	Aminotransferase
DZM45_RS02000	COG1335	isochorismatase
DZM45_RS02035	COG2261	transglycosylase associated protein
DZM45_RS02040	COG0588	phosphoglycerate mutase activity
DZM45_RS02075	COG1024	Enoyl-CoA hydratase
DZM45_RS02100	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DZM45_RS02105	COG1028	Short-chain dehydrogenase reductase Sdr
DZM45_RS02110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DZM45_RS02125	COG0439	Biotin carboxylase
DZM45_RS02150	COG3716	PTS system mannose fructose sorbose family IID component
DZM45_RS02155	COG3715	PTS system
DZM45_RS02165	COG0561	phosphatase activity
DZM45_RS02170	COG2252	PERMEase
DZM45_RS02175	COG0802	atpase or kinase
DZM45_RS02185	COG1316	TRANSCRIPTIONal
DZM45_RS02195	COG0537	adenosine 5'-monophosphoramidase activity
DZM45_RS02200	COG1131	(ABC) transporter
DZM45_RS02205	COG4473	ABC transporter
DZM45_RS02225	COG4974	Belongs to the 'phage' integrase family
DZM45_RS02345	COG1783	phage Terminase large subunit
DZM45_RS02465	COG1705	Flagellar rod assembly protein muramidase FlgJ
DZM45_RS02485	COG0195	Participates in both transcription termination and antitermination
DZM45_RS02490	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DZM45_RS02520	COG2217	Heavy metal translocating P-type atpase
DZM45_RS02575	COG2860	membrane
DZM45_RS02580	COG0561	phosphatase activity
DZM45_RS02600	COG1283	sodium-dependent phosphate transmembrane transporter activity
DZM45_RS02610	COG0656	L-ascorbic acid biosynthetic process
DZM45_RS02615	COG1755	Isoprenylcysteine carboxyl methyltransferase
DZM45_RS02655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DZM45_RS02660	COG0446	pyridine nucleotide-disulphide oxidoreductase
DZM45_RS02685	COG1131	(ABC) transporter
DZM45_RS02720	COG0768	penicillin binding
DZM45_RS02730	COG0513	Belongs to the DEAD box helicase family
DZM45_RS02740	COG1126	abc transporter atp-binding protein
DZM45_RS02750	COG0492	ferredoxin-NADP+ reductase activity
DZM45_RS02755	COG1113	amino acid transport
DZM45_RS02760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DZM45_RS02770	COG3579	cysteine-type endopeptidase activity
DZM45_RS02775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DZM45_RS02800	COG0116	Belongs to the methyltransferase superfamily
DZM45_RS02815	COG2610	gluconate transmembrane transporter activity
DZM45_RS02820	COG1028	Short-chain dehydrogenase reductase Sdr
DZM45_RS02830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DZM45_RS02835	COG0183	Belongs to the thiolase family
DZM45_RS02840	COG0583	DNA-binding transcription factor activity
DZM45_RS02860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DZM45_RS02870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DZM45_RS02870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DZM45_RS02880	COG0515	serine threonine protein kinase
DZM45_RS02880	COG2815	serine threonine protein kinase
DZM45_RS02890	COG4585	Histidine kinase
DZM45_RS02895	COG2197	response regulator
DZM45_RS02905	COG1098	S1 RNA binding domain
DZM45_RS02915	COG1739	Uncharacterized protein family UPF0029
DZM45_RS02920	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DZM45_RS03030	COG0383	alpha-mannosidase activity
DZM45_RS03040	COG1609	Transcriptional regulator
DZM45_RS03045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DZM45_RS03050	COG2723	6-phospho-beta-galactosidase activity
DZM45_RS03060	COG1175	transmembrane transport
DZM45_RS03065	COG0395	ABC-type sugar transport system, permease component
DZM45_RS03070	COG1653	transport
DZM45_RS03080	COG2972	Histidine kinase
DZM45_RS03085	COG2207	Transcriptional regulator
DZM45_RS03085	COG4753	response regulator
DZM45_RS03090	COG3250	beta-galactosidase activity
DZM45_RS03100	COG2226	methyltransferase
DZM45_RS03120	COG1605	Chorismate mutase
DZM45_RS03120	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DZM45_RS03160	COG1396	sequence-specific DNA binding
DZM45_RS03200	COG1674	ftsk spoiiie
DZM45_RS03250	COG0433	COG0433 Predicted ATPase
DZM45_RS03305	COG5433	transposase activity
DZM45_RS03365	COG1518	maintenance of DNA repeat elements
DZM45_RS03370	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DZM45_RS03375	COG0785	Cytochrome C biogenesis protein
DZM45_RS03380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DZM45_RS03395	COG2972	Histidine kinase
DZM45_RS03420	COG2235	arginine
DZM45_RS03435	COG1288	antiporter activity
DZM45_RS03440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DZM45_RS03445	COG0549	Belongs to the carbamate kinase family
DZM45_RS03455	COG0742	ribosomal rna small subunit methyltransferase
DZM45_RS03465	COG3480	Lon protease (S16) C-terminal proteolytic domain
DZM45_RS03470	COG1609	Transcriptional regulator
DZM45_RS03475	COG4470	Protein conserved in bacteria
DZM45_RS03490	COG0783	Belongs to the Dps family
DZM45_RS03500	COG1940	carbohydrate kinase activity
DZM45_RS03505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DZM45_RS03510	COG1217	gtp-binding protein TYPA
DZM45_RS03545	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DZM45_RS03560	COG2302	S4 RNA-binding domain
DZM45_RS03565	COG3599	regulation of cell shape
DZM45_RS03580	COG0494	nUDIX hydrolase
DZM45_RS03585	COG0542	response to heat
DZM45_RS03590	COG4703	Protein of unknown function (DUF1797)
DZM45_RS03595	COG0765	amino acid transport
DZM45_RS03605	COG0415	Belongs to the DNA photolyase family
DZM45_RS03610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DZM45_RS03635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DZM45_RS03640	COG1438	arginine binding
DZM45_RS03645	COG0497	DNA recombination
DZM45_RS03660	COG2755	lipolytic protein G-D-S-L family
DZM45_RS03675	COG2217	Heavy metal translocating P-type atpase
DZM45_RS03690	COG1827	regulation of RNA biosynthetic process
DZM45_RS03700	COG2116	formate transmembrane transporter activity
DZM45_RS03705	COG0768	penicillin binding
DZM45_RS03720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DZM45_RS03740	COG0513	Belongs to the DEAD box helicase family
DZM45_RS03755	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DZM45_RS03760	COG0204	Acyl-transferase
DZM45_RS03765	COG1555	photosystem II stabilization
DZM45_RS03765	COG1596	polysaccharide export
DZM45_RS03815	COG1187	pseudouridine synthase activity
DZM45_RS03830	COG2223	nitrite transmembrane transporter activity
DZM45_RS03835	COG4122	O-methyltransferase activity
DZM45_RS03850	COG1476	TRANSCRIPTIONal
DZM45_RS03880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DZM45_RS03885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DZM45_RS03905	COG0726	polysaccharide deacetylase
DZM45_RS03910	COG0513	Belongs to the DEAD box helicase family
DZM45_RS03930	COG1956	GAF domain-containing protein
DZM45_RS03935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DZM45_RS03940	COG5433	transposase activity
DZM45_RS03950	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DZM45_RS03950	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DZM45_RS03975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DZM45_RS03980	COG4109	DRTGG domain
DZM45_RS04095	COG2814	Major facilitator Superfamily
DZM45_RS04105	COG1187	pseudouridine synthase activity
DZM45_RS04135	COG2723	6-phospho-beta-galactosidase activity
DZM45_RS04145	COG3711	transcriptional antiterminator
DZM45_RS04145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DZM45_RS04155	COG1447	Phosphotransferase system cellobiose-specific component IIA
DZM45_RS04165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DZM45_RS04170	COG1126	abc transporter atp-binding protein
DZM45_RS04175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DZM45_RS04195	COG1696	Membrane protein involved in D-alanine export
DZM45_RS04205	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DZM45_RS04210	COG0657	acetylesterase activity
DZM45_RS04220	COG2182	Extracellular solute-binding protein
DZM45_RS04225	COG0366	Alpha amylase catalytic
DZM45_RS04235	COG1175	transmembrane transport
DZM45_RS04240	COG3833	ABC-type maltose transport systems, permease component
DZM45_RS04255	COG3833	ABC-type maltose transport systems, permease component
DZM45_RS04260	COG1175	transmembrane transport
DZM45_RS04265	COG2182	Extracellular solute-binding protein
DZM45_RS04270	COG1609	Transcriptional regulator
DZM45_RS04275	COG1640	4-alpha-glucanotransferase
DZM45_RS04280	COG0058	SHG alpha-glucan phosphorylase activity
DZM45_RS04305	COG1131	(ABC) transporter
DZM45_RS04310	COG1725	Transcriptional regulator
DZM45_RS04325	COG0469	pyruvate kinase activity
DZM45_RS04340	COG2824	Alkylphosphonate utilization operon protein PhnA
DZM45_RS04345	COG0765	amino acid transport
DZM45_RS04350	COG1126	abc transporter atp-binding protein
DZM45_RS04355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DZM45_RS04365	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DZM45_RS04370	COG1115	amino acid carrier protein
DZM45_RS04420	COG1136	(ABC) transporter
DZM45_RS04420	COG4591	ABC-type transport system involved in lipoprotein release permease component
DZM45_RS04450	COG0196	riboflavin kinase activity
DZM45_RS04465	COG0483	inositol monophosphate 1-phosphatase activity
DZM45_RS04470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DZM45_RS04470	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DZM45_RS04480	COG0573	inorganic phosphate transmembrane transporter activity
DZM45_RS04485	COG0581	inorganic phosphate transmembrane transporter activity
DZM45_RS04500	COG0704	Plays a role in the regulation of phosphate uptake
DZM45_RS04515	COG0745	RESPONSE REGULATOR receiver
DZM45_RS04520	COG5002	protein histidine kinase activity
DZM45_RS04535	COG2813	Specifically methylates the guanine in position
DZM45_RS04540	COG0295	cytidine deaminase activity
DZM45_RS04545	COG1744	ABC transporter substrate-binding protein PnrA-like
DZM45_RS04550	COG3845	ABC transporter
DZM45_RS04555	COG4603	Belongs to the binding-protein-dependent transport system permease family
DZM45_RS04560	COG1079	Belongs to the binding-protein-dependent transport system permease family
DZM45_RS04565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DZM45_RS04570	COG4684	Psort location CytoplasmicMembrane, score
DZM45_RS04575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DZM45_RS04595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DZM45_RS04625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DZM45_RS04630	COG1328	CTP reductase activity
DZM45_RS04630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DZM45_RS04635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DZM45_RS04640	COG0352	thiamine-phosphate diphosphorylase activity
DZM45_RS04640	COG0351	phosphomethylpyrimidine kinase
DZM45_RS04650	COG0488	(ABC) transporter
DZM45_RS04670	COG2188	Transcriptional regulator
DZM45_RS04680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DZM45_RS04700	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DZM45_RS04730	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DZM45_RS04735	COG0511	ligase activity, forming carbon-carbon bonds
DZM45_RS04745	COG2851	Citrate transporter
DZM45_RS04760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DZM45_RS04765	COG0511	ligase activity, forming carbon-carbon bonds
DZM45_RS04815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DZM45_RS04820	COG0758	DNA mediated transformation
DZM45_RS04840	COG1272	protein, Hemolysin III
DZM45_RS04845	COG1597	lipid kinase activity
DZM45_RS04860	COG0346	lactoylglutathione lyase activity
DZM45_RS04865	COG3764	Sortase (surface protein transpeptidase)
DZM45_RS04885	COG1132	(ABC) transporter
DZM45_RS04890	COG1132	(ABC) transporter
DZM45_RS04920	COG2890	protein-(glutamine-N5) methyltransferase activity
DZM45_RS04945	COG2233	PERMEase
DZM45_RS04965	COG1174	glycine betaine transport
DZM45_RS04980	COG4221	oxidoreductase activity
DZM45_RS04985	COG0280	phosphate acetyltransferase
DZM45_RS04990	COG0564	pseudouridine synthase activity
DZM45_RS05000	COG2357	RelA SpoT domain protein
DZM45_RS05015	COG1104	cysteine desulfurase activity
DZM45_RS05030	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DZM45_RS05040	COG0628	permease
DZM45_RS05050	COG0038	chloride channel
DZM45_RS05055	COG3700	Belongs to the class B bacterial acid phosphatase family
DZM45_RS05060	COG1063	alcohol dehydrogenase
DZM45_RS05070	COG3493	citrate carrier protein
DZM45_RS05075	COG3290	protein histidine kinase activity
DZM45_RS05080	COG4565	transcriptional regulatory protein
DZM45_RS05090	COG1177	transmembrane transport
DZM45_RS05095	COG1176	ABC-type spermidine putrescine transport system, permease component I
DZM45_RS05110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DZM45_RS05130	COG0285	dihydrofolate synthase activity
DZM45_RS05160	COG1396	sequence-specific DNA binding
DZM45_RS05175	COG1131	(ABC) transporter
DZM45_RS05250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DZM45_RS05265	COG1012	belongs to the aldehyde dehydrogenase family
DZM45_RS05275	COG4753	response regulator
DZM45_RS05275	COG2207	Transcriptional regulator
DZM45_RS05280	COG2972	Histidine kinase
DZM45_RS05285	COG3716	PTS system mannose fructose sorbose family IID component
DZM45_RS05290	COG3715	PTS system
DZM45_RS05330	COG5433	transposase activity
DZM45_RS05340	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DZM45_RS05345	COG1518	maintenance of DNA repeat elements
DZM45_RS05360	COG0647	UMP catabolic process
DZM45_RS05370	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DZM45_RS05390	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DZM45_RS05395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DZM45_RS05400	COG3442	glutamine amidotransferase
DZM45_RS05405	COG0095	Lipoate-protein ligase
DZM45_RS05410	COG5492	domain, Protein
DZM45_RS05430	COG0508	dehydrogenase complex catalyzes the overall conversion of
DZM45_RS05435	COG0022	dehydrogenase e1 component
DZM45_RS05435	COG0508	dehydrogenase complex catalyzes the overall conversion of
DZM45_RS05440	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DZM45_RS05445	COG0488	(ABC) transporter
DZM45_RS05465	COG1129	ABC transporter
DZM45_RS05485	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DZM45_RS05490	COG0457	Tetratricopeptide repeat
DZM45_RS05495	COG0628	permease
DZM45_RS05500	COG1051	belongs to the nudix hydrolase family
DZM45_RS05505	COG1088	dTDP-glucose 4,6-dehydratase activity
DZM45_RS05515	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DZM45_RS05520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DZM45_RS05530	COG2384	SAM-dependent methyltransferase
DZM45_RS05535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DZM45_RS05550	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DZM45_RS05550	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DZM45_RS05555	COG0300	oxidoreductase activity
DZM45_RS05565	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DZM45_RS05570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DZM45_RS05615	COG0539	negative regulation of cytoplasmic translation
DZM45_RS05635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DZM45_RS05645	COG0187	DNA topoisomerase II activity
DZM45_RS05665	COG0765	amino acid transport
DZM45_RS05670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DZM45_RS05695	COG0583	DNA-binding transcription factor activity
DZM45_RS05710	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DZM45_RS05755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DZM45_RS05765	COG3425	synthase
DZM45_RS05800	COG0745	RESPONSE REGULATOR receiver
DZM45_RS05805	COG2357	RelA SpoT domain protein
DZM45_RS05810	COG0737	Belongs to the 5'-nucleotidase family
DZM45_RS05815	COG0242	peptide deformylase activity
DZM45_RS05825	COG0488	(ABC) transporter
DZM45_RS05845	COG0105	UTP biosynthetic process
DZM45_RS05865	COG1705	Flagellar rod assembly protein muramidase FlgJ
DZM45_RS05865	COG1388	LysM domain
DZM45_RS05870	COG1705	Flagellar rod assembly protein muramidase FlgJ
DZM45_RS05870	COG1388	LysM domain
DZM45_RS05875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DZM45_RS05875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DZM45_RS05875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DZM45_RS05880	COG1105	Belongs to the carbohydrate kinase PfkB family
DZM45_RS05885	COG1349	DNA-binding transcription factor activity
DZM45_RS05935	COG1837	Belongs to the UPF0109 family
DZM45_RS05945	COG0584	glycerophosphoryl diester phosphodiesterase
DZM45_RS05950	COG0577	efflux transmembrane transporter activity
DZM45_RS05955	COG1136	(ABC) transporter
DZM45_RS05960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DZM45_RS05995	COG0564	pseudouridine synthase activity
DZM45_RS06015	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DZM45_RS06040	COG1104	cysteine desulfurase activity
DZM45_RS06050	COG0285	dihydrofolate synthase activity
DZM45_RS06055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DZM45_RS06075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DZM45_RS06080	COG1368	sulfuric ester hydrolase activity
DZM45_RS06140	COG1216	Glycosyl transferase, family 2
DZM45_RS06185	COG2151	metal-sulfur cluster biosynthetic enzyme
DZM45_RS06190	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DZM45_RS06195	COG0358	DNA primase activity
DZM45_RS06200	COG1970	mechanosensitive ion channel activity
DZM45_RS06210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DZM45_RS06225	COG2321	neutral zinc metallopeptidase
DZM45_RS06235	COG0577	efflux transmembrane transporter activity
DZM45_RS06320	COG1597	lipid kinase activity
DZM45_RS06330	COG4708	membrane
DZM45_RS06355	COG1131	(ABC) transporter
DZM45_RS06450	COG0038	chloride channel
DZM45_RS06460	COG0716	FMN binding
DZM45_RS06465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DZM45_RS06475	COG2222	sugar isomerase
DZM45_RS06480	COG2188	Transcriptional regulator
DZM45_RS06515	COG0436	Aminotransferase
DZM45_RS06520	COG1199	ATP-dependent helicase activity
DZM45_RS06520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DZM45_RS06535	COG2177	Part of the ABC transporter FtsEX involved in
DZM45_RS06540	COG2884	Cell division ATP-binding protein ftsE
DZM45_RS06550	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DZM45_RS06560	COG0546	phosphoglycolate phosphatase activity
DZM45_RS06565	COG0800	Aldolase
DZM45_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
DZM45_RS06595	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DZM45_RS06600	COG3715	PTS system
DZM45_RS06605	COG3716	PTS system mannose fructose sorbose family IID component
DZM45_RS06615	COG1609	Transcriptional regulator
DZM45_RS06630	COG1078	dGTPase activity
DZM45_RS06665	COG0772	Belongs to the SEDS family
DZM45_RS06675	COG1164	Oligoendopeptidase f
DZM45_RS06680	COG0386	Belongs to the glutathione peroxidase family
DZM45_RS06725	COG4443	Transcriptional Coactivator p15 (PC4)
DZM45_RS06730	COG0826	peptidase U32
DZM45_RS06775	COG2183	response to ionizing radiation
DZM45_RS06785	COG0701	Predicted permease
DZM45_RS06790	COG3689	TIGRFAM TIGR03943 family protein
DZM45_RS06800	COG1263	PTS System
DZM45_RS06800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DZM45_RS06800	COG2190	(PTS) system
DZM45_RS06805	COG3711	transcriptional antiterminator
DZM45_RS06810	COG0477	Major facilitator Superfamily
DZM45_RS06815	COG0552	protein localization to endoplasmic reticulum
DZM45_RS06820	COG0561	phosphatase activity
DZM45_RS06825	COG0561	phosphatase activity
DZM45_RS06920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DZM45_RS06935	COG1196	nuclear chromosome segregation
DZM45_RS06945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DZM45_RS06950	COG5002	protein histidine kinase activity
DZM45_RS06955	COG0745	RESPONSE REGULATOR receiver
DZM45_RS06970	COG0183	Belongs to the thiolase family
DZM45_RS06990	COG4555	ABC transporter
DZM45_RS07000	COG0438	transferase activity, transferring glycosyl groups
DZM45_RS07010	COG1609	Transcriptional regulator
DZM45_RS07015	COG0006	proline dipeptidase activity
DZM45_RS07020	COG0778	Nitroreductase
DZM45_RS07030	COG0463	Glycosyl transferase, family 2
DZM45_RS07060	COG0557	exoribonuclease II activity
DZM45_RS07075	COG2814	Major facilitator Superfamily
DZM45_RS07080	COG0433	COG0433 Predicted ATPase
DZM45_RS07185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DZM45_RS07195	COG1573	uracil-dna glycosylase
DZM45_RS07200	COG1702	phosphate starvation-inducible protein PhoH
DZM45_RS07290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DZM45_RS07300	COG0494	nUDIX hydrolase
DZM45_RS07315	COG0673	inositol 2-dehydrogenase activity
DZM45_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
DZM45_RS07420	COG1304	FMN binding
DZM45_RS07430	COG0708	Exodeoxyribonuclease III
DZM45_RS07435	COG1393	Belongs to the ArsC family
DZM45_RS07460	COG0470	DNA polymerase III
DZM45_RS07490	COG2244	polysaccharide biosynthetic process
DZM45_RS07500	COG1120	ATPase activity
DZM45_RS07505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DZM45_RS07510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DZM45_RS07515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DZM45_RS07530	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DZM45_RS07535	COG1253	flavin adenine dinucleotide binding
DZM45_RS07540	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DZM45_RS07545	COG1242	4 iron, 4 sulfur cluster binding
DZM45_RS07550	COG0671	phosphoesterase, PA-phosphatase related
DZM45_RS07555	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DZM45_RS07570	COG1187	pseudouridine synthase activity
DZM45_RS07625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DZM45_RS07630	COG1254	Belongs to the acylphosphatase family
DZM45_RS07645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DZM45_RS07665	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DZM45_RS07675	COG1484	DNA-dependent DNA replication
DZM45_RS07695	COG0745	RESPONSE REGULATOR receiver
DZM45_RS07710	COG1704	LemA family
DZM45_RS07720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DZM45_RS07725	COG0569	domain protein
DZM45_RS07735	COG1114	Component of the transport system for branched-chain amino acids
DZM45_RS07750	COG1464	Belongs to the NlpA lipoprotein family
DZM45_RS07755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DZM45_RS07775	COG2226	methyltransferase
DZM45_RS07780	COG0799	negative regulation of ribosome biogenesis
DZM45_RS07785	COG1713	HD superfamily hydrolase involved in NAD metabolism
DZM45_RS07795	COG1534	Rna-binding protein
DZM45_RS07800	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DZM45_RS07805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DZM45_RS07845	COG1929	Belongs to the glycerate kinase type-1 family
DZM45_RS07850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DZM45_RS07880	COG0577	efflux transmembrane transporter activity
DZM45_RS07885	COG1136	(ABC) transporter
DZM45_RS07910	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DZM45_RS07910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DZM45_RS07915	COG1447	Phosphotransferase system cellobiose-specific component IIA
DZM45_RS07965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DZM45_RS07970	COG1476	TRANSCRIPTIONal
DZM45_RS07990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DZM45_RS08000	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DZM45_RS08020	COG1045	serine acetyltransferase
DZM45_RS08035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DZM45_RS08050	COG3711	transcriptional antiterminator
DZM45_RS08075	COG0431	NADPH-dependent FMN reductase
DZM45_RS08080	COG1846	Transcriptional regulator
DZM45_RS08100	COG4589	Belongs to the CDS family
DZM45_RS08110	COG1862	Preprotein translocase
DZM45_RS08120	COG1523	belongs to the glycosyl hydrolase 13 family
DZM45_RS08135	COG3842	ATPase activity
DZM45_RS08175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DZM45_RS08175	COG1263	PTS System
DZM45_RS08175	COG2190	(PTS) system
DZM45_RS08180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DZM45_RS08195	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DZM45_RS08200	COG0512	Glutamine amidotransferase of anthranilate synthase
DZM45_RS08205	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DZM45_RS08240	COG0601	transmembrane transport
DZM45_RS08250	COG1122	ATPase activity
DZM45_RS08270	COG0803	Belongs to the bacterial solute-binding protein 9 family
DZM45_RS08275	COG5433	transposase activity
DZM45_RS08305	COG3711	transcriptional antiterminator
DZM45_RS08320	COG1705	Flagellar rod assembly protein muramidase FlgJ
DZM45_RS08320	COG3942	CHAP domain
DZM45_RS08325	COG2205	protein histidine kinase activity
DZM45_RS08330	COG0745	RESPONSE REGULATOR receiver
DZM45_RS08335	COG0577	efflux transmembrane transporter activity
DZM45_RS08340	COG1136	(ABC) transporter
DZM45_RS08415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DZM45_RS08430	COG1882	Formate acetyltransferase
DZM45_RS08435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DZM45_RS08440	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DZM45_RS08445	COG1447	Phosphotransferase system cellobiose-specific component IIA
DZM45_RS08450	COG2390	Transcriptional regulator
DZM45_RS08455	COG1349	DNA-binding transcription factor activity
DZM45_RS08460	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DZM45_RS08480	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DZM45_RS08495	COG0564	pseudouridine synthase activity
DZM45_RS08530	COG0542	response to heat
DZM45_RS08535	COG4463	regulation of RNA biosynthetic process
DZM45_RS08550	COG0450	alkyl hydroperoxide reductase
DZM45_RS08565	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DZM45_RS08575	COG3404	Formiminotransferase-cyclodeaminase
DZM45_RS08590	COG0531	amino acid
DZM45_RS08620	COG3590	peptidase
DZM45_RS08625	COG0366	Alpha amylase catalytic
DZM45_RS08630	COG1263	PTS System
DZM45_RS08630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DZM45_RS08635	COG2188	Transcriptional regulator
DZM45_RS08650	COG2514	catechol 2,3-dioxygenase activity
DZM45_RS08660	COG0602	queuosine metabolic process
DZM45_RS08675	COG1328	CTP reductase activity
DZM45_RS08700	COG1393	Belongs to the ArsC family
DZM45_RS08715	COG0519	Catalyzes the synthesis of GMP from XMP
DZM45_RS08760	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DZM45_RS08765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DZM45_RS08770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DZM45_RS08855	COG1511	domain protein
DZM45_RS08975	COG0582	viral genome integration into host DNA
DZM45_RS08990	COG0305	Participates in initiation and elongation during chromosome replication
DZM45_RS09020	COG1760	l-serine dehydratase
DZM45_RS09025	COG1760	l-serine dehydratase
DZM45_RS09030	COG0741	lytic transglycosylase activity
DZM45_RS09035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DZM45_RS09050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DZM45_RS09060	COG0612	Peptidase, M16
DZM45_RS09080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DZM45_RS09100	COG0517	IMP dehydrogenase activity
DZM45_RS09100	COG0516	GMP reductase activity
DZM45_RS09110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DZM45_RS09115	COG0488	(ABC) transporter
DZM45_RS09150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DZM45_RS09155	COG1475	DNA binding