locus-tag	class	description
MTB314_RS00010	COG0592	DNA-directed DNA polymerase activity
MTB314_RS00020	COG0012	GTP binding
MTB314_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MTB314_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MTB314_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MTB314_RS00065	COG0531	amino acid
MTB314_RS00240	COG3942	CHAP domain
MTB314_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MTB314_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MTB314_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MTB314_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MTB314_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MTB314_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MTB314_RS00350	COG1454	alcohol dehydrogenase
MTB314_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
MTB314_RS00355	COG1064	alcohol dehydrogenase
MTB314_RS00360	COG0534	Mate efflux family protein
MTB314_RS00470	COG0201	protein transport
MTB314_RS00605	COG1121	(ABC) transporter
MTB314_RS00610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MTB314_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTB314_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MTB314_RS00650	COG1459	type II secretion system
MTB314_RS00655	COG4537	Required for transformation and DNA binding
MTB314_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MTB314_RS00700	COG1363	Peptidase, m42
MTB314_RS00710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTB314_RS00715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MTB314_RS00725	COG1428	Deoxynucleoside kinase
MTB314_RS00730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MTB314_RS00760	COG4509	Sortase family
MTB314_RS00770	COG4372	Transposase
MTB314_RS00795	COG2031	fatty acid transporter
MTB314_RS00810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTB314_RS00825	COG0251	oxidation-reduction process
MTB314_RS00840	COG1269	ATP hydrolysis coupled proton transport
MTB314_RS00845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MTB314_RS00855	COG1527	subunit (C
MTB314_RS00860	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
MTB314_RS00895	COG1744	ABC transporter substrate-binding protein PnrA-like
MTB314_RS00935	COG0626	cystathionine gamma-synthase activity
MTB314_RS00965	COG3623	hexulose-6-phosphate isomerase
MTB314_RS00985	COG3448	diguanylate cyclase activity
MTB314_RS00985	COG4175	Glycine betaine
MTB314_RS00995	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTB314_RS00995	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MTB314_RS01015	COG3969	phosphoadenosine phosphosulfate
MTB314_RS01020	COG1475	DNA binding
MTB314_RS01030	COG2801	Transposase and inactivated derivatives
MTB314_RS01035	COG2801	Transposase and inactivated derivatives
MTB314_RS01050	COG0157	Belongs to the NadC ModD family
MTB314_RS01055	COG2801	Transposase and inactivated derivatives
MTB314_RS01075	COG1268	BioY protein
MTB314_RS01080	COG1234	tRNA 3'-trailer cleavage
MTB314_RS01115	COG5433	transposase activity
MTB314_RS01130	COG0457	Tetratricopeptide repeat
MTB314_RS01130	COG0705	Rhomboid family
MTB314_RS01150	COG1132	(ABC) transporter
MTB314_RS01155	COG1132	(ABC) transporter
MTB314_RS01165	COG0756	dUTP diphosphatase activity
MTB314_RS01190	COG3290	protein histidine kinase activity
MTB314_RS01215	COG1847	R3H domain protein
MTB314_RS01235	COG1175	transmembrane transport
MTB314_RS01240	COG0395	ABC-type sugar transport system, permease component
MTB314_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MTB314_RS01265	COG0084	hydrolase, TatD family'
MTB314_RS01290	COG1564	THIamine pyrophosphokinase
MTB314_RS01305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MTB314_RS01340	COG0765	amino acid transport
MTB314_RS01360	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MTB314_RS01370	COG0719	Fe-S assembly protein
MTB314_RS01375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MTB314_RS01390	COG1686	Belongs to the peptidase S11 family
MTB314_RS01395	COG1686	Belongs to the peptidase S11 family
MTB314_RS01400	COG4166	transmembrane transport
MTB314_RS01405	COG0601	transmembrane transport
MTB314_RS01410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MTB314_RS01415	COG0444	Belongs to the ABC transporter superfamily
MTB314_RS01475	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
MTB314_RS01480	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MTB314_RS01485	COG1534	Rna-binding protein
MTB314_RS01495	COG1713	HD superfamily hydrolase involved in NAD metabolism
MTB314_RS01500	COG0799	negative regulation of ribosome biogenesis
MTB314_RS01505	COG2226	methyltransferase
MTB314_RS01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTB314_RS01525	COG1464	Belongs to the NlpA lipoprotein family
MTB314_RS01540	COG1114	Component of the transport system for branched-chain amino acids
MTB314_RS01550	COG0569	domain protein
MTB314_RS01555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MTB314_RS01565	COG1704	LemA family
MTB314_RS01580	COG0745	RESPONSE REGULATOR receiver
MTB314_RS01600	COG1484	DNA-dependent DNA replication
MTB314_RS01610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MTB314_RS01630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MTB314_RS01645	COG1254	Belongs to the acylphosphatase family
MTB314_RS01665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTB314_RS01720	COG1187	pseudouridine synthase activity
MTB314_RS01735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MTB314_RS01740	COG0671	phosphoesterase, PA-phosphatase related
MTB314_RS01745	COG1242	4 iron, 4 sulfur cluster binding
MTB314_RS01750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MTB314_RS01755	COG1253	flavin adenine dinucleotide binding
MTB314_RS01760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MTB314_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTB314_RS01780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MTB314_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MTB314_RS01790	COG1120	ATPase activity
MTB314_RS01800	COG2244	polysaccharide biosynthetic process
MTB314_RS01825	COG0470	DNA polymerase III
MTB314_RS01855	COG1393	Belongs to the ArsC family
MTB314_RS01860	COG0708	Exodeoxyribonuclease III
MTB314_RS01870	COG1304	FMN binding
MTB314_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
MTB314_RS01955	COG0673	inositol 2-dehydrogenase activity
MTB314_RS01970	COG0494	nUDIX hydrolase
MTB314_RS01980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MTB314_RS02070	COG1702	phosphate starvation-inducible protein PhoH
MTB314_RS02075	COG1573	uracil-dna glycosylase
MTB314_RS02085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MTB314_RS02110	COG3328	transposase activity
MTB314_RS02115	COG3328	transposase activity
MTB314_RS02170	COG0433	COG0433 Predicted ATPase
MTB314_RS02175	COG2814	Major facilitator Superfamily
MTB314_RS02185	COG0557	exoribonuclease II activity
MTB314_RS02215	COG0463	Glycosyl transferase, family 2
MTB314_RS02225	COG0778	Nitroreductase
MTB314_RS02230	COG0006	proline dipeptidase activity
MTB314_RS02235	COG1609	Transcriptional regulator
MTB314_RS02245	COG0438	transferase activity, transferring glycosyl groups
MTB314_RS02255	COG4555	ABC transporter
MTB314_RS02275	COG0183	Belongs to the thiolase family
MTB314_RS02290	COG0745	RESPONSE REGULATOR receiver
MTB314_RS02295	COG5002	protein histidine kinase activity
MTB314_RS02300	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MTB314_RS02310	COG1196	nuclear chromosome segregation
MTB314_RS02320	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MTB314_RS02390	COG4695	Portal protein
MTB314_RS02440	COG0561	phosphatase activity
MTB314_RS02445	COG0561	phosphatase activity
MTB314_RS02450	COG0552	protein localization to endoplasmic reticulum
MTB314_RS02455	COG0477	Major facilitator Superfamily
MTB314_RS02460	COG3711	transcriptional antiterminator
MTB314_RS02465	COG1263	PTS System
MTB314_RS02465	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTB314_RS02465	COG2190	(PTS) system
MTB314_RS02475	COG3689	TIGRFAM TIGR03943 family protein
MTB314_RS02480	COG0701	Predicted permease
MTB314_RS02485	COG2183	response to ionizing radiation
MTB314_RS02530	COG0826	peptidase U32
MTB314_RS02535	COG4443	Transcriptional Coactivator p15 (PC4)
MTB314_RS02580	COG0386	Belongs to the glutathione peroxidase family
MTB314_RS02585	COG1164	Oligoendopeptidase f
MTB314_RS02595	COG0772	Belongs to the SEDS family
MTB314_RS02630	COG1078	dGTPase activity
MTB314_RS02645	COG1609	Transcriptional regulator
MTB314_RS02655	COG3716	PTS system mannose fructose sorbose family IID component
MTB314_RS02660	COG3715	PTS system
MTB314_RS02665	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTB314_RS02680	COG1028	Short-chain dehydrogenase reductase Sdr
MTB314_RS02695	COG0800	Aldolase
MTB314_RS02700	COG0546	phosphoglycolate phosphatase activity
MTB314_RS02705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MTB314_RS02715	COG2884	Cell division ATP-binding protein ftsE
MTB314_RS02720	COG2177	Part of the ABC transporter FtsEX involved in
MTB314_RS02735	COG1199	ATP-dependent helicase activity
MTB314_RS02735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MTB314_RS02740	COG0436	Aminotransferase
MTB314_RS02775	COG2188	Transcriptional regulator
MTB314_RS02780	COG2222	sugar isomerase
MTB314_RS02790	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MTB314_RS02795	COG0716	FMN binding
MTB314_RS02805	COG0038	chloride channel
MTB314_RS02895	COG1131	(ABC) transporter
MTB314_RS02915	COG4708	membrane
MTB314_RS02925	COG1597	lipid kinase activity
MTB314_RS03010	COG0577	efflux transmembrane transporter activity
MTB314_RS03020	COG2321	neutral zinc metallopeptidase
MTB314_RS03035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTB314_RS03045	COG1970	mechanosensitive ion channel activity
MTB314_RS03050	COG0358	DNA primase activity
MTB314_RS03055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MTB314_RS03060	COG2151	metal-sulfur cluster biosynthetic enzyme
MTB314_RS03105	COG1216	Glycosyl transferase, family 2
MTB314_RS03160	COG1368	sulfuric ester hydrolase activity
MTB314_RS03165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MTB314_RS03185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MTB314_RS03200	COG1104	cysteine desulfurase activity
MTB314_RS03225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MTB314_RS03230	COG0583	DNA-binding transcription factor activity
MTB314_RS03240	COG0564	pseudouridine synthase activity
MTB314_RS03270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MTB314_RS03275	COG1136	(ABC) transporter
MTB314_RS03280	COG0577	efflux transmembrane transporter activity
MTB314_RS03285	COG0584	glycerophosphoryl diester phosphodiesterase
MTB314_RS03295	COG1837	Belongs to the UPF0109 family
MTB314_RS03345	COG1349	DNA-binding transcription factor activity
MTB314_RS03350	COG1105	Belongs to the carbohydrate kinase PfkB family
MTB314_RS03355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTB314_RS03355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MTB314_RS03355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTB314_RS03360	COG1388	LysM domain
MTB314_RS03360	COG1705	Flagellar rod assembly protein muramidase FlgJ
MTB314_RS03365	COG1705	Flagellar rod assembly protein muramidase FlgJ
MTB314_RS03365	COG1388	LysM domain
MTB314_RS03370	COG2801	Transposase and inactivated derivatives
MTB314_RS03385	COG0105	UTP biosynthetic process
MTB314_RS03405	COG0488	(ABC) transporter
MTB314_RS03415	COG0242	peptide deformylase activity
MTB314_RS03420	COG0737	Belongs to the 5'-nucleotidase family
MTB314_RS03425	COG2357	RelA SpoT domain protein
MTB314_RS03430	COG0745	RESPONSE REGULATOR receiver
MTB314_RS03465	COG3425	synthase
MTB314_RS03475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MTB314_RS03530	COG0583	DNA-binding transcription factor activity
MTB314_RS03555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTB314_RS03560	COG0765	amino acid transport
MTB314_RS03580	COG0187	DNA topoisomerase II activity
MTB314_RS03590	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MTB314_RS03610	COG0539	negative regulation of cytoplasmic translation
MTB314_RS03645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MTB314_RS03650	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
MTB314_RS03660	COG0300	oxidoreductase activity
MTB314_RS03665	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MTB314_RS03665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MTB314_RS03680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MTB314_RS03685	COG2384	SAM-dependent methyltransferase
MTB314_RS03695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MTB314_RS03700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MTB314_RS03710	COG1088	dTDP-glucose 4,6-dehydratase activity
MTB314_RS03715	COG1051	belongs to the nudix hydrolase family
MTB314_RS03720	COG0628	permease
MTB314_RS03725	COG0457	Tetratricopeptide repeat
MTB314_RS03730	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MTB314_RS03745	COG1129	ABC transporter
MTB314_RS03765	COG0488	(ABC) transporter
MTB314_RS03770	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MTB314_RS03775	COG0022	dehydrogenase e1 component
MTB314_RS03775	COG0508	dehydrogenase complex catalyzes the overall conversion of
MTB314_RS03795	COG5492	domain, Protein
MTB314_RS03800	COG0095	Lipoate-protein ligase
MTB314_RS03805	COG3442	glutamine amidotransferase
MTB314_RS03810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MTB314_RS03815	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MTB314_RS03835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MTB314_RS03845	COG0647	UMP catabolic process
MTB314_RS03860	COG1518	maintenance of DNA repeat elements
MTB314_RS03865	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MTB314_RS03880	COG0105	UTP biosynthetic process
MTB314_RS03915	COG3715	PTS system
MTB314_RS03920	COG3716	PTS system mannose fructose sorbose family IID component
MTB314_RS03925	COG2972	Histidine kinase
MTB314_RS03930	COG4753	response regulator
MTB314_RS03930	COG2207	Transcriptional regulator
MTB314_RS03935	COG1840	ABC-type Fe3 transport system, periplasmic component
MTB314_RS03950	COG1011	Hydrolase
MTB314_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
MTB314_RS03970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTB314_RS04030	COG1131	(ABC) transporter
MTB314_RS04045	COG1396	sequence-specific DNA binding
MTB314_RS04080	COG0285	dihydrofolate synthase activity
MTB314_RS04100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MTB314_RS04115	COG1176	ABC-type spermidine putrescine transport system, permease component I
MTB314_RS04120	COG1177	transmembrane transport
MTB314_RS04130	COG4565	transcriptional regulatory protein
MTB314_RS04135	COG3290	protein histidine kinase activity
MTB314_RS04140	COG3493	citrate carrier protein
MTB314_RS04155	COG3700	Belongs to the class B bacterial acid phosphatase family
MTB314_RS04160	COG0038	chloride channel
MTB314_RS04170	COG0628	permease
MTB314_RS04180	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MTB314_RS04195	COG1104	cysteine desulfurase activity
MTB314_RS04210	COG2357	RelA SpoT domain protein
MTB314_RS04220	COG0564	pseudouridine synthase activity
MTB314_RS04225	COG0280	phosphate acetyltransferase
MTB314_RS04245	COG1174	glycine betaine transport
MTB314_RS04260	COG2233	PERMEase
MTB314_RS04285	COG2890	protein-(glutamine-N5) methyltransferase activity
MTB314_RS04315	COG1132	(ABC) transporter
MTB314_RS04320	COG1132	(ABC) transporter
MTB314_RS04340	COG3764	Sortase (surface protein transpeptidase)
MTB314_RS04345	COG0346	lactoylglutathione lyase activity
MTB314_RS04360	COG1272	protein, Hemolysin III
MTB314_RS04380	COG0758	DNA mediated transformation
MTB314_RS04385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MTB314_RS04430	COG0511	ligase activity, forming carbon-carbon bonds
MTB314_RS04435	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MTB314_RS04450	COG2851	Citrate transporter
MTB314_RS04460	COG0511	ligase activity, forming carbon-carbon bonds
MTB314_RS04465	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MTB314_RS04495	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MTB314_RS04515	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MTB314_RS04525	COG2188	Transcriptional regulator
MTB314_RS04545	COG0488	(ABC) transporter
MTB314_RS04555	COG0351	phosphomethylpyrimidine kinase
MTB314_RS04555	COG0352	thiamine-phosphate diphosphorylase activity
MTB314_RS04560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MTB314_RS04565	COG1328	CTP reductase activity
MTB314_RS04565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MTB314_RS04570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MTB314_RS04600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MTB314_RS04620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MTB314_RS04625	COG4684	Psort location CytoplasmicMembrane, score
MTB314_RS04630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTB314_RS04635	COG1079	Belongs to the binding-protein-dependent transport system permease family
MTB314_RS04640	COG4603	Belongs to the binding-protein-dependent transport system permease family
MTB314_RS04645	COG3845	ABC transporter
MTB314_RS04650	COG1744	ABC transporter substrate-binding protein PnrA-like
MTB314_RS04655	COG0295	cytidine deaminase activity
MTB314_RS04660	COG2813	Specifically methylates the guanine in position
MTB314_RS04675	COG5002	protein histidine kinase activity
MTB314_RS04680	COG0745	RESPONSE REGULATOR receiver
MTB314_RS04690	COG0704	Plays a role in the regulation of phosphate uptake
MTB314_RS04705	COG0581	inorganic phosphate transmembrane transporter activity
MTB314_RS04710	COG0573	inorganic phosphate transmembrane transporter activity
MTB314_RS04720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MTB314_RS04720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MTB314_RS04725	COG0483	inositol monophosphate 1-phosphatase activity
MTB314_RS04740	COG0196	riboflavin kinase activity
MTB314_RS04770	COG1136	(ABC) transporter
MTB314_RS04770	COG4591	ABC-type transport system involved in lipoprotein release permease component
MTB314_RS04820	COG1115	amino acid carrier protein
MTB314_RS04825	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MTB314_RS04835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTB314_RS04840	COG1126	abc transporter atp-binding protein
MTB314_RS04845	COG0765	amino acid transport
MTB314_RS04850	COG2824	Alkylphosphonate utilization operon protein PhnA
MTB314_RS04865	COG0469	pyruvate kinase activity
MTB314_RS04880	COG1725	Transcriptional regulator
MTB314_RS04885	COG1131	(ABC) transporter
MTB314_RS04945	COG1396	sequence-specific DNA binding
MTB314_RS04985	COG0058	SHG alpha-glucan phosphorylase activity
MTB314_RS04990	COG1640	4-alpha-glucanotransferase
MTB314_RS04995	COG1609	Transcriptional regulator
MTB314_RS05000	COG2182	Extracellular solute-binding protein
MTB314_RS05005	COG1175	transmembrane transport
MTB314_RS05010	COG3833	ABC-type maltose transport systems, permease component
MTB314_RS05025	COG3833	ABC-type maltose transport systems, permease component
MTB314_RS05030	COG1175	transmembrane transport
MTB314_RS05040	COG0366	Alpha amylase catalytic
MTB314_RS05045	COG2182	Extracellular solute-binding protein
MTB314_RS05055	COG0657	acetylesterase activity
MTB314_RS05060	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MTB314_RS05070	COG1696	Membrane protein involved in D-alanine export
MTB314_RS05090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MTB314_RS05095	COG1126	abc transporter atp-binding protein
MTB314_RS05100	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTB314_RS05110	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTB314_RS05120	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MTB314_RS05120	COG3711	transcriptional antiterminator
MTB314_RS05130	COG2723	6-phospho-beta-galactosidase activity
MTB314_RS05155	COG1187	pseudouridine synthase activity
MTB314_RS05165	COG2814	Major facilitator Superfamily
MTB314_RS05245	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MTB314_RS05245	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MTB314_RS05250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MTB314_RS05255	COG1956	GAF domain-containing protein
MTB314_RS05275	COG0513	Belongs to the DEAD box helicase family
MTB314_RS05280	COG0726	polysaccharide deacetylase
MTB314_RS05300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MTB314_RS05305	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTB314_RS05310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MTB314_RS05325	COG2801	Transposase and inactivated derivatives
MTB314_RS05335	COG2801	Transposase and inactivated derivatives
MTB314_RS05350	COG1476	TRANSCRIPTIONal
MTB314_RS05365	COG4122	O-methyltransferase activity
MTB314_RS05370	COG2223	nitrite transmembrane transporter activity
MTB314_RS05385	COG1187	pseudouridine synthase activity
MTB314_RS05435	COG1596	polysaccharide export
MTB314_RS05435	COG1555	photosystem II stabilization
MTB314_RS05440	COG0204	Acyl-transferase
MTB314_RS05445	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MTB314_RS05460	COG0513	Belongs to the DEAD box helicase family
MTB314_RS05475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MTB314_RS05490	COG0768	penicillin binding
MTB314_RS05495	COG2116	formate transmembrane transporter activity
MTB314_RS05505	COG1827	regulation of RNA biosynthetic process
MTB314_RS05520	COG2217	Heavy metal translocating P-type atpase
MTB314_RS05660	COG3935	DnaD domain protein
MTB314_RS05690	COG3561	AntA/AntB antirepressor
MTB314_RS05700	COG1396	sequence-specific DNA binding
MTB314_RS05715	COG0582	viral genome integration into host DNA
MTB314_RS05730	COG2755	lipolytic protein G-D-S-L family
MTB314_RS05745	COG0497	DNA recombination
MTB314_RS05750	COG1438	arginine binding
MTB314_RS05755	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MTB314_RS05780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MTB314_RS05785	COG0415	Belongs to the DNA photolyase family
MTB314_RS05795	COG0765	amino acid transport
MTB314_RS05800	COG4703	Protein of unknown function (DUF1797)
MTB314_RS05805	COG0542	response to heat
MTB314_RS05810	COG0494	nUDIX hydrolase
MTB314_RS05825	COG3599	regulation of cell shape
MTB314_RS05830	COG2302	S4 RNA-binding domain
MTB314_RS05880	COG1217	gtp-binding protein TYPA
MTB314_RS05885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MTB314_RS05890	COG1940	carbohydrate kinase activity
MTB314_RS05900	COG0783	Belongs to the Dps family
MTB314_RS05915	COG4470	Protein conserved in bacteria
MTB314_RS05925	COG3480	Lon protease (S16) C-terminal proteolytic domain
MTB314_RS05935	COG0742	ribosomal rna small subunit methyltransferase
MTB314_RS05945	COG0549	Belongs to the carbamate kinase family
MTB314_RS05950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MTB314_RS05955	COG1288	antiporter activity
MTB314_RS05970	COG2235	arginine
MTB314_RS05995	COG2972	Histidine kinase
MTB314_RS06010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MTB314_RS06015	COG0785	Cytochrome C biogenesis protein
MTB314_RS06020	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MTB314_RS06025	COG1518	maintenance of DNA repeat elements
MTB314_RS06085	COG1605	Chorismate mutase
MTB314_RS06085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
MTB314_RS06105	COG2226	methyltransferase
MTB314_RS06115	COG3250	beta-galactosidase activity
MTB314_RS06120	COG2207	Transcriptional regulator
MTB314_RS06120	COG4753	response regulator
MTB314_RS06125	COG2972	Histidine kinase
MTB314_RS06135	COG1653	transport
MTB314_RS06140	COG0395	ABC-type sugar transport system, permease component
MTB314_RS06145	COG1175	transmembrane transport
MTB314_RS06150	COG1940	carbohydrate kinase activity
MTB314_RS06155	COG2723	6-phospho-beta-galactosidase activity
MTB314_RS06160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
MTB314_RS06175	COG0383	alpha-mannosidase activity
MTB314_RS06265	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MTB314_RS06270	COG1739	Uncharacterized protein family UPF0029
MTB314_RS06280	COG1098	S1 RNA binding domain
MTB314_RS06290	COG2197	response regulator
MTB314_RS06295	COG4585	Histidine kinase
MTB314_RS06305	COG2815	serine threonine protein kinase
MTB314_RS06305	COG0515	serine threonine protein kinase
MTB314_RS06315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MTB314_RS06315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MTB314_RS06325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MTB314_RS06350	COG0183	Belongs to the thiolase family
MTB314_RS06355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MTB314_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
MTB314_RS06370	COG2610	gluconate transmembrane transporter activity
MTB314_RS06385	COG0116	Belongs to the methyltransferase superfamily
MTB314_RS06410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTB314_RS06415	COG3579	cysteine-type endopeptidase activity
MTB314_RS06425	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MTB314_RS06430	COG1113	amino acid transport
MTB314_RS06435	COG0492	ferredoxin-NADP+ reductase activity
MTB314_RS06445	COG1126	abc transporter atp-binding protein
MTB314_RS06455	COG0513	Belongs to the DEAD box helicase family
MTB314_RS06465	COG0768	penicillin binding
MTB314_RS06505	COG1131	(ABC) transporter
MTB314_RS06530	COG0446	pyridine nucleotide-disulphide oxidoreductase
MTB314_RS06535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTB314_RS06570	COG1755	Isoprenylcysteine carboxyl methyltransferase
MTB314_RS06575	COG0656	L-ascorbic acid biosynthetic process
MTB314_RS06585	COG1283	sodium-dependent phosphate transmembrane transporter activity
MTB314_RS06605	COG0561	phosphatase activity
MTB314_RS06610	COG2860	membrane
MTB314_RS06660	COG2217	Heavy metal translocating P-type atpase
MTB314_RS06690	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MTB314_RS06695	COG0195	Participates in both transcription termination and antitermination
MTB314_RS06720	COG4473	ABC transporter
MTB314_RS06725	COG1131	(ABC) transporter
MTB314_RS06730	COG0537	adenosine 5'-monophosphoramidase activity
MTB314_RS06740	COG1316	TRANSCRIPTIONal
MTB314_RS06750	COG0802	atpase or kinase
MTB314_RS06755	COG2252	PERMEase
MTB314_RS06760	COG0561	phosphatase activity
MTB314_RS06770	COG3715	PTS system
MTB314_RS06775	COG3716	PTS system mannose fructose sorbose family IID component
MTB314_RS06800	COG0439	Biotin carboxylase
MTB314_RS06815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MTB314_RS06820	COG1028	Short-chain dehydrogenase reductase Sdr
MTB314_RS06825	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MTB314_RS06850	COG1024	Enoyl-CoA hydratase
MTB314_RS06885	COG0588	phosphoglycerate mutase activity
MTB314_RS06890	COG2261	transglycosylase associated protein
MTB314_RS06915	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MTB314_RS06915	COG0574	Belongs to the PEP-utilizing enzyme family
MTB314_RS06920	COG1335	isochorismatase
MTB314_RS06930	COG0436	Aminotransferase
MTB314_RS06940	COG0561	phosphatase activity
MTB314_RS06945	COG0252	asparaginase activity
MTB314_RS06960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MTB314_RS06965	COG1129	ABC transporter
MTB314_RS06980	COG1132	(ABC) transporter
MTB314_RS06985	COG4988	ABC transporter
MTB314_RS06990	COG1120	ATPase activity
MTB314_RS07015	COG3942	CHAP domain
MTB314_RS07015	COG1388	LysM domain
MTB314_RS07050	COG1482	cell wall glycoprotein biosynthetic process
MTB314_RS07055	COG1940	carbohydrate kinase activity
MTB314_RS07065	COG1263	PTS System
MTB314_RS07065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTB314_RS07065	COG2190	(PTS) system
MTB314_RS07070	COG1621	beta-fructofuranosidase activity
MTB314_RS07075	COG1609	Transcriptional regulator
MTB314_RS07095	COG2131	deaminase
MTB314_RS07100	COG0006	proline dipeptidase activity
MTB314_RS07140	COG1194	a g-specific adenine glycosylase
MTB314_RS07150	COG3118	belongs to the thioredoxin family
MTB314_RS07180	COG0681	Belongs to the peptidase S26 family
MTB314_RS07185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MTB314_RS07200	COG1882	Formate acetyltransferase
MTB314_RS07205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MTB314_RS07220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MTB314_RS07225	COG2814	Major facilitator Superfamily
MTB314_RS07230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MTB314_RS07255	COG0789	Transcriptional regulator
MTB314_RS07270	COG2081	HI0933 family
MTB314_RS07280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MTB314_RS07285	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MTB314_RS07305	COG0456	acetyltransferase
MTB314_RS07310	COG1214	PFAM Peptidase M22, glycoprotease
MTB314_RS07325	COG0174	glutamine synthetase
MTB314_RS07330	COG0789	Transcriptional regulator
MTB314_RS07345	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
MTB314_RS07370	COG5433	transposase activity
MTB314_RS07410	COG0668	transmembrane transport
MTB314_RS07425	COG0351	phosphomethylpyrimidine kinase
MTB314_RS07470	COG1929	Belongs to the glycerate kinase type-1 family
MTB314_RS07475	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
MTB314_RS07485	COG0577	efflux transmembrane transporter activity
MTB314_RS07490	COG1136	(ABC) transporter
MTB314_RS07515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTB314_RS07515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTB314_RS07520	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTB314_RS07570	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MTB314_RS07575	COG1476	TRANSCRIPTIONal
MTB314_RS07595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MTB314_RS07605	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MTB314_RS07620	COG1045	serine acetyltransferase
MTB314_RS07635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MTB314_RS07640	COG3037	sugar-specific permease SgaT UlaA
MTB314_RS07650	COG3711	transcriptional antiterminator
MTB314_RS07675	COG1846	Transcriptional regulator
MTB314_RS07695	COG4589	Belongs to the CDS family
MTB314_RS07705	COG1862	Preprotein translocase
MTB314_RS07715	COG1523	belongs to the glycosyl hydrolase 13 family
MTB314_RS07725	COG3842	ATPase activity
MTB314_RS07765	COG2190	(PTS) system
MTB314_RS07765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTB314_RS07765	COG1263	PTS System
MTB314_RS07770	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MTB314_RS07785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MTB314_RS07790	COG0512	Glutamine amidotransferase of anthranilate synthase
MTB314_RS07795	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MTB314_RS07835	COG0601	transmembrane transport
MTB314_RS07845	COG1122	ATPase activity
MTB314_RS07865	COG0803	Belongs to the bacterial solute-binding protein 9 family
MTB314_RS07905	COG3711	transcriptional antiterminator
MTB314_RS07915	COG1705	Flagellar rod assembly protein muramidase FlgJ
MTB314_RS07915	COG3942	CHAP domain
MTB314_RS07920	COG2205	protein histidine kinase activity
MTB314_RS07925	COG0745	RESPONSE REGULATOR receiver
MTB314_RS07930	COG0577	efflux transmembrane transporter activity
MTB314_RS07935	COG1136	(ABC) transporter
MTB314_RS07985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MTB314_RS08000	COG1882	Formate acetyltransferase
MTB314_RS08005	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTB314_RS08010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MTB314_RS08015	COG1447	Phosphotransferase system cellobiose-specific component IIA
MTB314_RS08020	COG2390	Transcriptional regulator
MTB314_RS08025	COG1349	DNA-binding transcription factor activity
MTB314_RS08030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MTB314_RS08045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MTB314_RS08060	COG0564	pseudouridine synthase activity
MTB314_RS08090	COG0542	response to heat
MTB314_RS08095	COG4463	regulation of RNA biosynthetic process
MTB314_RS08110	COG0450	alkyl hydroperoxide reductase
MTB314_RS08125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MTB314_RS08135	COG3404	Formiminotransferase-cyclodeaminase
MTB314_RS08150	COG0531	amino acid
MTB314_RS08180	COG3590	peptidase
MTB314_RS08185	COG0366	Alpha amylase catalytic
MTB314_RS08190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MTB314_RS08190	COG1263	PTS System
MTB314_RS08195	COG2188	Transcriptional regulator
MTB314_RS08205	COG2514	catechol 2,3-dioxygenase activity
MTB314_RS08215	COG0602	queuosine metabolic process
MTB314_RS08230	COG1328	CTP reductase activity
MTB314_RS08255	COG1393	Belongs to the ArsC family
MTB314_RS08270	COG0519	Catalyzes the synthesis of GMP from XMP
MTB314_RS08280	COG2814	Major facilitator Superfamily
MTB314_RS08315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTB314_RS08320	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTB314_RS08325	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTB314_RS08405	COG1511	domain protein
MTB314_RS08440	COG0305	Participates in initiation and elongation during chromosome replication
MTB314_RS08470	COG1760	l-serine dehydratase
MTB314_RS08475	COG1760	l-serine dehydratase
MTB314_RS08480	COG0741	lytic transglycosylase activity
MTB314_RS08485	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MTB314_RS08500	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MTB314_RS08520	COG1215	transferase activity, transferring glycosyl groups
MTB314_RS08550	COG0516	GMP reductase activity
MTB314_RS08550	COG0517	IMP dehydrogenase activity
MTB314_RS08560	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MTB314_RS08565	COG0488	(ABC) transporter
MTB314_RS08605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MTB314_RS08610	COG1475	DNA binding