locus-tag	class	description
DI45_RS00005	COG1475	DNA binding
DI45_RS00015	COG0592	DNA-directed DNA polymerase activity
DI45_RS00025	COG0012	GTP binding
DI45_RS00035	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DI45_RS00040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DI45_RS00065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DI45_RS00070	COG0531	amino acid
DI45_RS00245	COG3942	CHAP domain
DI45_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DI45_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DI45_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DI45_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DI45_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DI45_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DI45_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
DI45_RS00355	COG1454	alcohol dehydrogenase
DI45_RS00360	COG1064	alcohol dehydrogenase
DI45_RS00365	COG0534	Mate efflux family protein
DI45_RS00475	COG0201	protein transport
DI45_RS00590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DI45_RS00610	COG1121	(ABC) transporter
DI45_RS00615	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DI45_RS00630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DI45_RS00650	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DI45_RS00655	COG1459	type II secretion system
DI45_RS00660	COG4537	Required for transformation and DNA binding
DI45_RS00700	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DI45_RS00705	COG1363	Peptidase, m42
DI45_RS00715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DI45_RS00720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DI45_RS00735	COG1428	Deoxynucleoside kinase
DI45_RS00740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DI45_RS00785	COG4509	Sortase family
DI45_RS00810	COG2031	fatty acid transporter
DI45_RS00830	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DI45_RS00845	COG0251	oxidation-reduction process
DI45_RS00860	COG1269	ATP hydrolysis coupled proton transport
DI45_RS00865	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DI45_RS00875	COG1527	subunit (C
DI45_RS00880	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
DI45_RS00915	COG1744	ABC transporter substrate-binding protein PnrA-like
DI45_RS00955	COG0626	cystathionine gamma-synthase activity
DI45_RS00985	COG3623	hexulose-6-phosphate isomerase
DI45_RS01005	COG4175	Glycine betaine
DI45_RS01005	COG3448	diguanylate cyclase activity
DI45_RS01015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DI45_RS01015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DI45_RS01035	COG3969	phosphoadenosine phosphosulfate
DI45_RS01040	COG1475	DNA binding
DI45_RS01050	COG2801	Transposase and inactivated derivatives
DI45_RS01055	COG2801	Transposase and inactivated derivatives
DI45_RS01070	COG0157	Belongs to the NadC ModD family
DI45_RS01075	COG2801	Transposase and inactivated derivatives
DI45_RS01095	COG1268	BioY protein
DI45_RS01100	COG5433	transposase activity
DI45_RS01110	COG1234	tRNA 3'-trailer cleavage
DI45_RS01140	COG0705	Rhomboid family
DI45_RS01140	COG0457	Tetratricopeptide repeat
DI45_RS01160	COG1132	(ABC) transporter
DI45_RS01165	COG1132	(ABC) transporter
DI45_RS01175	COG0756	dUTP diphosphatase activity
DI45_RS01200	COG3290	protein histidine kinase activity
DI45_RS01225	COG1847	R3H domain protein
DI45_RS01245	COG1175	transmembrane transport
DI45_RS01250	COG0395	ABC-type sugar transport system, permease component
DI45_RS01260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DI45_RS01275	COG0084	hydrolase, TatD family'
DI45_RS01300	COG1564	THIamine pyrophosphokinase
DI45_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DI45_RS01355	COG0765	amino acid transport
DI45_RS01375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DI45_RS01385	COG0719	Fe-S assembly protein
DI45_RS01390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DI45_RS01405	COG1686	Belongs to the peptidase S11 family
DI45_RS01410	COG1686	Belongs to the peptidase S11 family
DI45_RS01415	COG4166	transmembrane transport
DI45_RS01420	COG0601	transmembrane transport
DI45_RS01425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DI45_RS01430	COG0444	Belongs to the ABC transporter superfamily
DI45_RS01480	COG5433	transposase activity
DI45_RS01490	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
DI45_RS01495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DI45_RS01500	COG1534	Rna-binding protein
DI45_RS01510	COG1713	HD superfamily hydrolase involved in NAD metabolism
DI45_RS01515	COG0799	negative regulation of ribosome biogenesis
DI45_RS01520	COG2226	methyltransferase
DI45_RS01535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DI45_RS01540	COG1464	Belongs to the NlpA lipoprotein family
DI45_RS01555	COG1114	Component of the transport system for branched-chain amino acids
DI45_RS01565	COG0569	domain protein
DI45_RS01570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DI45_RS01580	COG1704	LemA family
DI45_RS01595	COG0745	RESPONSE REGULATOR receiver
DI45_RS01615	COG1484	DNA-dependent DNA replication
DI45_RS01625	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DI45_RS01645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DI45_RS01660	COG1254	Belongs to the acylphosphatase family
DI45_RS01665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DI45_RS01720	COG1187	pseudouridine synthase activity
DI45_RS01735	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DI45_RS01740	COG0671	phosphoesterase, PA-phosphatase related
DI45_RS01745	COG1242	4 iron, 4 sulfur cluster binding
DI45_RS01750	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DI45_RS01755	COG1253	flavin adenine dinucleotide binding
DI45_RS01760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DI45_RS01775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DI45_RS01780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DI45_RS01785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DI45_RS01790	COG1120	ATPase activity
DI45_RS01800	COG2244	polysaccharide biosynthetic process
DI45_RS01825	COG0470	DNA polymerase III
DI45_RS01850	COG1393	Belongs to the ArsC family
DI45_RS01855	COG0708	Exodeoxyribonuclease III
DI45_RS01865	COG1304	FMN binding
DI45_RS01880	COG5433	transposase activity
DI45_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
DI45_RS01975	COG0673	inositol 2-dehydrogenase activity
DI45_RS01990	COG0494	nUDIX hydrolase
DI45_RS02000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DI45_RS02090	COG1702	phosphate starvation-inducible protein PhoH
DI45_RS02095	COG1573	uracil-dna glycosylase
DI45_RS02105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DI45_RS02120	COG2274	protein secretion by the type I secretion system
DI45_RS02125	COG2274	protein secretion by the type I secretion system
DI45_RS02160	COG2801	Transposase and inactivated derivatives
DI45_RS02165	COG2801	Transposase and inactivated derivatives
DI45_RS02175	COG3279	Response regulator of the LytR AlgR family
DI45_RS02190	COG2274	protein secretion by the type I secretion system
DI45_RS02260	COG0433	COG0433 Predicted ATPase
DI45_RS02265	COG2814	Major facilitator Superfamily
DI45_RS02275	COG0557	exoribonuclease II activity
DI45_RS02305	COG0463	Glycosyl transferase, family 2
DI45_RS02315	COG0778	Nitroreductase
DI45_RS02320	COG0006	proline dipeptidase activity
DI45_RS02325	COG1609	Transcriptional regulator
DI45_RS02335	COG0438	transferase activity, transferring glycosyl groups
DI45_RS02345	COG4555	ABC transporter
DI45_RS02365	COG0183	Belongs to the thiolase family
DI45_RS02380	COG0745	RESPONSE REGULATOR receiver
DI45_RS02385	COG5002	protein histidine kinase activity
DI45_RS02390	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DI45_RS02400	COG1196	nuclear chromosome segregation
DI45_RS02410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DI45_RS02515	COG0561	phosphatase activity
DI45_RS02520	COG0561	phosphatase activity
DI45_RS02525	COG0552	protein localization to endoplasmic reticulum
DI45_RS02530	COG0477	Major facilitator Superfamily
DI45_RS02535	COG3711	transcriptional antiterminator
DI45_RS02540	COG1263	PTS System
DI45_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DI45_RS02540	COG2190	(PTS) system
DI45_RS02550	COG3689	TIGRFAM TIGR03943 family protein
DI45_RS02555	COG0701	Predicted permease
DI45_RS02565	COG2183	response to ionizing radiation
DI45_RS02610	COG0826	peptidase U32
DI45_RS02615	COG4443	Transcriptional Coactivator p15 (PC4)
DI45_RS02665	COG0386	Belongs to the glutathione peroxidase family
DI45_RS02670	COG1164	Oligoendopeptidase f
DI45_RS02680	COG0772	Belongs to the SEDS family
DI45_RS02715	COG1078	dGTPase activity
DI45_RS02735	COG1609	Transcriptional regulator
DI45_RS02745	COG3716	PTS system mannose fructose sorbose family IID component
DI45_RS02750	COG3715	PTS system
DI45_RS02755	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DI45_RS02770	COG1028	Short-chain dehydrogenase reductase Sdr
DI45_RS02785	COG0800	Aldolase
DI45_RS02790	COG0546	phosphoglycolate phosphatase activity
DI45_RS02795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DI45_RS02805	COG2884	Cell division ATP-binding protein ftsE
DI45_RS02810	COG2177	Part of the ABC transporter FtsEX involved in
DI45_RS02825	COG1199	ATP-dependent helicase activity
DI45_RS02825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DI45_RS02830	COG0436	Aminotransferase
DI45_RS02865	COG3620	sequence-specific DNA binding
DI45_RS02920	COG3723	Recombinational DNA repair protein, rece pathway
DI45_RS03115	COG3177	Filamentation induced by cAMP protein fic
DI45_RS03130	COG2217	Heavy metal translocating P-type atpase
DI45_RS03145	COG1827	regulation of RNA biosynthetic process
DI45_RS03155	COG2116	formate transmembrane transporter activity
DI45_RS03160	COG0768	penicillin binding
DI45_RS03175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DI45_RS03190	COG0513	Belongs to the DEAD box helicase family
DI45_RS03205	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
DI45_RS03210	COG0204	Acyl-transferase
DI45_RS03215	COG1555	photosystem II stabilization
DI45_RS03215	COG1596	polysaccharide export
DI45_RS03220	COG2333	competence protein COMEC
DI45_RS03220	COG0658	competence protein
DI45_RS03265	COG1187	pseudouridine synthase activity
DI45_RS03280	COG2223	nitrite transmembrane transporter activity
DI45_RS03285	COG4122	O-methyltransferase activity
DI45_RS03300	COG1476	TRANSCRIPTIONal
DI45_RS03315	COG2801	Transposase and inactivated derivatives
DI45_RS03320	COG2801	Transposase and inactivated derivatives
DI45_RS03335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DI45_RS03340	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DI45_RS03345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DI45_RS03365	COG0726	polysaccharide deacetylase
DI45_RS03370	COG0513	Belongs to the DEAD box helicase family
DI45_RS03390	COG1956	GAF domain-containing protein
DI45_RS03395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DI45_RS03400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
DI45_RS03400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
DI45_RS03430	COG4109	DRTGG domain
DI45_RS03480	COG2814	Major facilitator Superfamily
DI45_RS03490	COG1187	pseudouridine synthase activity
DI45_RS03495	COG2801	Transposase and inactivated derivatives
DI45_RS03525	COG5433	transposase activity
DI45_RS03530	COG2723	6-phospho-beta-galactosidase activity
DI45_RS03540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DI45_RS03540	COG3711	transcriptional antiterminator
DI45_RS03550	COG1447	Phosphotransferase system cellobiose-specific component IIA
DI45_RS03560	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DI45_RS03565	COG1126	abc transporter atp-binding protein
DI45_RS03570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DI45_RS03590	COG1696	Membrane protein involved in D-alanine export
DI45_RS03600	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DI45_RS03605	COG0657	acetylesterase activity
DI45_RS03615	COG2182	Extracellular solute-binding protein
DI45_RS03620	COG0366	Alpha amylase catalytic
DI45_RS03630	COG1175	transmembrane transport
DI45_RS03635	COG3833	ABC-type maltose transport systems, permease component
DI45_RS03650	COG3833	ABC-type maltose transport systems, permease component
DI45_RS03655	COG1175	transmembrane transport
DI45_RS03660	COG2182	Extracellular solute-binding protein
DI45_RS03665	COG1609	Transcriptional regulator
DI45_RS03670	COG1640	4-alpha-glucanotransferase
DI45_RS03675	COG0058	SHG alpha-glucan phosphorylase activity
DI45_RS03840	COG1598	PFAM Uncharacterised protein family UPF0150
DI45_RS03995	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS04025	COG1131	(ABC) transporter
DI45_RS04030	COG1725	Transcriptional regulator
DI45_RS04045	COG0469	pyruvate kinase activity
DI45_RS04060	COG2824	Alkylphosphonate utilization operon protein PhnA
DI45_RS04065	COG0765	amino acid transport
DI45_RS04070	COG1126	abc transporter atp-binding protein
DI45_RS04075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DI45_RS04085	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DI45_RS04090	COG1115	amino acid carrier protein
DI45_RS04140	COG4591	ABC-type transport system involved in lipoprotein release permease component
DI45_RS04140	COG1136	(ABC) transporter
DI45_RS04170	COG0196	riboflavin kinase activity
DI45_RS04185	COG0483	inositol monophosphate 1-phosphatase activity
DI45_RS04190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DI45_RS04190	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DI45_RS04200	COG0573	inorganic phosphate transmembrane transporter activity
DI45_RS04205	COG0581	inorganic phosphate transmembrane transporter activity
DI45_RS04220	COG0704	Plays a role in the regulation of phosphate uptake
DI45_RS04230	COG0745	RESPONSE REGULATOR receiver
DI45_RS04235	COG5002	protein histidine kinase activity
DI45_RS04250	COG2813	Specifically methylates the guanine in position
DI45_RS04255	COG0295	cytidine deaminase activity
DI45_RS04260	COG1744	ABC transporter substrate-binding protein PnrA-like
DI45_RS04265	COG3845	ABC transporter
DI45_RS04270	COG4603	Belongs to the binding-protein-dependent transport system permease family
DI45_RS04275	COG1079	Belongs to the binding-protein-dependent transport system permease family
DI45_RS04280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DI45_RS04285	COG4684	Psort location CytoplasmicMembrane, score
DI45_RS04290	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DI45_RS04300	COG0095	Lipoate-protein ligase
DI45_RS04310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DI45_RS04340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DI45_RS04345	COG1328	CTP reductase activity
DI45_RS04345	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DI45_RS04350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DI45_RS04355	COG0351	phosphomethylpyrimidine kinase
DI45_RS04355	COG0352	thiamine-phosphate diphosphorylase activity
DI45_RS04365	COG0488	(ABC) transporter
DI45_RS04385	COG2188	Transcriptional regulator
DI45_RS04395	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DI45_RS04415	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DI45_RS04450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DI45_RS04455	COG0511	ligase activity, forming carbon-carbon bonds
DI45_RS04465	COG2851	Citrate transporter
DI45_RS04480	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
DI45_RS04485	COG0511	ligase activity, forming carbon-carbon bonds
DI45_RS04530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DI45_RS04535	COG0758	DNA mediated transformation
DI45_RS04555	COG1272	protein, Hemolysin III
DI45_RS04560	COG1597	lipid kinase activity
DI45_RS04570	COG0346	lactoylglutathione lyase activity
DI45_RS04575	COG3764	Sortase (surface protein transpeptidase)
DI45_RS04600	COG1132	(ABC) transporter
DI45_RS04630	COG2890	protein-(glutamine-N5) methyltransferase activity
DI45_RS04655	COG2233	PERMEase
DI45_RS04670	COG1174	glycine betaine transport
DI45_RS04685	COG4221	oxidoreductase activity
DI45_RS04690	COG0280	phosphate acetyltransferase
DI45_RS04695	COG0564	pseudouridine synthase activity
DI45_RS04705	COG2357	RelA SpoT domain protein
DI45_RS04720	COG1104	cysteine desulfurase activity
DI45_RS04735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DI45_RS04745	COG0628	permease
DI45_RS04755	COG0038	chloride channel
DI45_RS04760	COG3700	Belongs to the class B bacterial acid phosphatase family
DI45_RS04775	COG3493	citrate carrier protein
DI45_RS04780	COG3290	protein histidine kinase activity
DI45_RS04785	COG4565	transcriptional regulatory protein
DI45_RS04795	COG1177	transmembrane transport
DI45_RS04800	COG1176	ABC-type spermidine putrescine transport system, permease component I
DI45_RS04835	COG0285	dihydrofolate synthase activity
DI45_RS04875	COG1396	sequence-specific DNA binding
DI45_RS04890	COG1131	(ABC) transporter
DI45_RS04965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DI45_RS04980	COG1012	belongs to the aldehyde dehydrogenase family
DI45_RS04990	COG2207	Transcriptional regulator
DI45_RS04990	COG4753	response regulator
DI45_RS04995	COG2972	Histidine kinase
DI45_RS05000	COG3716	PTS system mannose fructose sorbose family IID component
DI45_RS05005	COG3715	PTS system
DI45_RS05045	COG0105	UTP biosynthetic process
DI45_RS05055	COG0647	UMP catabolic process
DI45_RS05065	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DI45_RS05085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DI45_RS05090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DI45_RS05095	COG3442	glutamine amidotransferase
DI45_RS05100	COG0095	Lipoate-protein ligase
DI45_RS05105	COG5492	domain, Protein
DI45_RS05120	COG0508	dehydrogenase complex catalyzes the overall conversion of
DI45_RS05125	COG0022	dehydrogenase e1 component
DI45_RS05125	COG0508	dehydrogenase complex catalyzes the overall conversion of
DI45_RS05130	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DI45_RS05135	COG0488	(ABC) transporter
DI45_RS05155	COG1129	ABC transporter
DI45_RS05170	COG5433	transposase activity
DI45_RS05180	COG1293	RNA-binding protein homologous to eukaryotic snRNP
DI45_RS05185	COG0457	Tetratricopeptide repeat
DI45_RS05190	COG0628	permease
DI45_RS05195	COG1051	belongs to the nudix hydrolase family
DI45_RS05200	COG1088	dTDP-glucose 4,6-dehydratase activity
DI45_RS05210	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DI45_RS05215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DI45_RS05225	COG2384	SAM-dependent methyltransferase
DI45_RS05230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DI45_RS05245	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
DI45_RS05245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DI45_RS05250	COG0300	oxidoreductase activity
DI45_RS05260	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
DI45_RS05265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DI45_RS05300	COG0539	negative regulation of cytoplasmic translation
DI45_RS05320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DI45_RS05330	COG0187	DNA topoisomerase II activity
DI45_RS05350	COG0765	amino acid transport
DI45_RS05380	COG0583	DNA-binding transcription factor activity
DI45_RS05440	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DI45_RS05450	COG3425	synthase
DI45_RS05485	COG0745	RESPONSE REGULATOR receiver
DI45_RS05490	COG2357	RelA SpoT domain protein
DI45_RS05495	COG0737	Belongs to the 5'-nucleotidase family
DI45_RS05500	COG0242	peptide deformylase activity
DI45_RS05510	COG0488	(ABC) transporter
DI45_RS05530	COG0105	UTP biosynthetic process
DI45_RS05555	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS05555	COG1388	LysM domain
DI45_RS05560	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS05560	COG1388	LysM domain
DI45_RS05565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DI45_RS05565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DI45_RS05565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DI45_RS05570	COG1105	Belongs to the carbohydrate kinase PfkB family
DI45_RS05575	COG1349	DNA-binding transcription factor activity
DI45_RS05625	COG1837	Belongs to the UPF0109 family
DI45_RS05635	COG0584	glycerophosphoryl diester phosphodiesterase
DI45_RS05640	COG0577	efflux transmembrane transporter activity
DI45_RS05645	COG1136	(ABC) transporter
DI45_RS05650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DI45_RS05680	COG0564	pseudouridine synthase activity
DI45_RS05690	COG0583	DNA-binding transcription factor activity
DI45_RS05695	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DI45_RS05720	COG1104	cysteine desulfurase activity
DI45_RS05730	COG0285	dihydrofolate synthase activity
DI45_RS05735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DI45_RS05755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DI45_RS05760	COG1368	sulfuric ester hydrolase activity
DI45_RS05815	COG1216	Glycosyl transferase, family 2
DI45_RS05860	COG2151	metal-sulfur cluster biosynthetic enzyme
DI45_RS05865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DI45_RS05870	COG0358	DNA primase activity
DI45_RS05875	COG1970	mechanosensitive ion channel activity
DI45_RS05885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DI45_RS05900	COG2321	neutral zinc metallopeptidase
DI45_RS05905	COG1136	(ABC) transporter
DI45_RS05910	COG0577	efflux transmembrane transporter activity
DI45_RS05940	COG5433	transposase activity
DI45_RS06005	COG1597	lipid kinase activity
DI45_RS06015	COG4708	membrane
DI45_RS06035	COG1131	(ABC) transporter
DI45_RS06125	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS06275	COG1475	DNA binding
DI45_RS06405	COG0582	viral genome integration into host DNA
DI45_RS06430	COG0038	chloride channel
DI45_RS06440	COG0716	FMN binding
DI45_RS06445	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
DI45_RS06455	COG2222	sugar isomerase
DI45_RS06460	COG2188	Transcriptional regulator
DI45_RS06485	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS06585	COG0740	serine-type endopeptidase activity
DI45_RS06625	COG1598	PFAM Uncharacterised protein family UPF0150
DI45_RS06700	COG3723	Recombinational DNA repair protein, rece pathway
DI45_RS06745	COG1396	sequence-specific DNA binding
DI45_RS06755	COG0582	viral genome integration into host DNA
DI45_RS06770	COG2755	lipolytic protein G-D-S-L family
DI45_RS06785	COG0497	DNA recombination
DI45_RS06790	COG1438	arginine binding
DI45_RS06795	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
DI45_RS06820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DI45_RS06825	COG0415	Belongs to the DNA photolyase family
DI45_RS06835	COG0765	amino acid transport
DI45_RS06840	COG4703	Protein of unknown function (DUF1797)
DI45_RS06845	COG0542	response to heat
DI45_RS06850	COG0494	nUDIX hydrolase
DI45_RS06865	COG3599	regulation of cell shape
DI45_RS06870	COG2302	S4 RNA-binding domain
DI45_RS06885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DI45_RS06910	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DI45_RS06920	COG1217	gtp-binding protein TYPA
DI45_RS06925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DI45_RS06930	COG1940	carbohydrate kinase activity
DI45_RS06940	COG0783	Belongs to the Dps family
DI45_RS06955	COG4470	Protein conserved in bacteria
DI45_RS06960	COG1609	Transcriptional regulator
DI45_RS06965	COG3480	Lon protease (S16) C-terminal proteolytic domain
DI45_RS06975	COG0742	ribosomal rna small subunit methyltransferase
DI45_RS06985	COG0549	Belongs to the carbamate kinase family
DI45_RS06990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DI45_RS06995	COG1288	antiporter activity
DI45_RS07010	COG2235	arginine
DI45_RS07035	COG2972	Histidine kinase
DI45_RS07050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DI45_RS07055	COG0785	Cytochrome C biogenesis protein
DI45_RS07065	COG0673	inositol 2-dehydrogenase activity
DI45_RS07100	COG5433	transposase activity
DI45_RS07110	COG1605	Chorismate mutase
DI45_RS07110	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DI45_RS07130	COG2226	methyltransferase
DI45_RS07140	COG3250	beta-galactosidase activity
DI45_RS07145	COG2207	Transcriptional regulator
DI45_RS07145	COG4753	response regulator
DI45_RS07150	COG2972	Histidine kinase
DI45_RS07160	COG1653	transport
DI45_RS07165	COG0395	ABC-type sugar transport system, permease component
DI45_RS07170	COG1175	transmembrane transport
DI45_RS07175	COG1940	carbohydrate kinase activity
DI45_RS07180	COG2723	6-phospho-beta-galactosidase activity
DI45_RS07185	COG3525	Glycosyl hydrolase, family 20, catalytic domain
DI45_RS07200	COG0383	alpha-mannosidase activity
DI45_RS07290	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DI45_RS07295	COG1739	Uncharacterized protein family UPF0029
DI45_RS07305	COG1098	S1 RNA binding domain
DI45_RS07315	COG2197	response regulator
DI45_RS07320	COG4585	Histidine kinase
DI45_RS07330	COG2815	serine threonine protein kinase
DI45_RS07330	COG0515	serine threonine protein kinase
DI45_RS07340	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DI45_RS07340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DI45_RS07350	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DI45_RS07370	COG0583	DNA-binding transcription factor activity
DI45_RS07375	COG0183	Belongs to the thiolase family
DI45_RS07380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DI45_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
DI45_RS07395	COG2610	gluconate transmembrane transporter activity
DI45_RS07410	COG0116	Belongs to the methyltransferase superfamily
DI45_RS07430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DI45_RS07435	COG3579	cysteine-type endopeptidase activity
DI45_RS07445	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DI45_RS07450	COG1113	amino acid transport
DI45_RS07455	COG0492	ferredoxin-NADP+ reductase activity
DI45_RS07465	COG1126	abc transporter atp-binding protein
DI45_RS07475	COG0513	Belongs to the DEAD box helicase family
DI45_RS07485	COG0768	penicillin binding
DI45_RS07520	COG1131	(ABC) transporter
DI45_RS07545	COG0446	pyridine nucleotide-disulphide oxidoreductase
DI45_RS07550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DI45_RS07585	COG1755	Isoprenylcysteine carboxyl methyltransferase
DI45_RS07590	COG0656	L-ascorbic acid biosynthetic process
DI45_RS07600	COG1283	sodium-dependent phosphate transmembrane transporter activity
DI45_RS07620	COG0561	phosphatase activity
DI45_RS07625	COG2860	membrane
DI45_RS07675	COG2217	Heavy metal translocating P-type atpase
DI45_RS07705	COG2740	Nucleic-acid-binding protein implicated in transcription termination
DI45_RS07710	COG0195	Participates in both transcription termination and antitermination
DI45_RS07735	COG4473	ABC transporter
DI45_RS07740	COG1131	(ABC) transporter
DI45_RS07745	COG0537	adenosine 5'-monophosphoramidase activity
DI45_RS07755	COG1316	TRANSCRIPTIONal
DI45_RS07765	COG0802	atpase or kinase
DI45_RS07770	COG2252	PERMEase
DI45_RS07775	COG0561	phosphatase activity
DI45_RS07785	COG3715	PTS system
DI45_RS07790	COG3716	PTS system mannose fructose sorbose family IID component
DI45_RS07815	COG0439	Biotin carboxylase
DI45_RS07830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DI45_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
DI45_RS07840	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DI45_RS07865	COG1024	Enoyl-CoA hydratase
DI45_RS07870	COG0484	heat shock protein binding
DI45_RS07900	COG0588	phosphoglycerate mutase activity
DI45_RS07905	COG2261	transglycosylase associated protein
DI45_RS07930	COG0574	Belongs to the PEP-utilizing enzyme family
DI45_RS07930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DI45_RS07935	COG1335	isochorismatase
DI45_RS07945	COG0436	Aminotransferase
DI45_RS07955	COG0561	phosphatase activity
DI45_RS07960	COG0252	asparaginase activity
DI45_RS07975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DI45_RS07980	COG1129	ABC transporter
DI45_RS07995	COG1132	(ABC) transporter
DI45_RS08000	COG4988	ABC transporter
DI45_RS08005	COG1120	ATPase activity
DI45_RS08030	COG3942	CHAP domain
DI45_RS08030	COG1388	LysM domain
DI45_RS08055	COG5433	transposase activity
DI45_RS08060	COG1482	cell wall glycoprotein biosynthetic process
DI45_RS08065	COG1940	carbohydrate kinase activity
DI45_RS08075	COG1263	PTS System
DI45_RS08075	COG2190	(PTS) system
DI45_RS08075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DI45_RS08080	COG1621	beta-fructofuranosidase activity
DI45_RS08085	COG1609	Transcriptional regulator
DI45_RS08105	COG2131	deaminase
DI45_RS08110	COG0006	proline dipeptidase activity
DI45_RS08150	COG1194	a g-specific adenine glycosylase
DI45_RS08160	COG3118	belongs to the thioredoxin family
DI45_RS08190	COG0681	Belongs to the peptidase S26 family
DI45_RS08195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DI45_RS08210	COG1882	Formate acetyltransferase
DI45_RS08215	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DI45_RS08225	COG5433	transposase activity
DI45_RS08240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DI45_RS08245	COG2814	Major facilitator Superfamily
DI45_RS08250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DI45_RS08275	COG0789	Transcriptional regulator
DI45_RS08290	COG2081	HI0933 family
DI45_RS08300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DI45_RS08305	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DI45_RS08325	COG0456	acetyltransferase
DI45_RS08330	COG1214	PFAM Peptidase M22, glycoprotease
DI45_RS08345	COG0174	glutamine synthetase
DI45_RS08350	COG0789	Transcriptional regulator
DI45_RS08365	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
DI45_RS08420	COG0668	transmembrane transport
DI45_RS08430	COG4720	Psort location CytoplasmicMembrane, score
DI45_RS08435	COG0351	phosphomethylpyrimidine kinase
DI45_RS08480	COG1929	Belongs to the glycerate kinase type-1 family
DI45_RS08485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DI45_RS08510	COG0577	efflux transmembrane transporter activity
DI45_RS08515	COG1136	(ABC) transporter
DI45_RS08540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DI45_RS08540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DI45_RS08545	COG1447	Phosphotransferase system cellobiose-specific component IIA
DI45_RS08595	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DI45_RS08600	COG1476	TRANSCRIPTIONal
DI45_RS08620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DI45_RS08630	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DI45_RS08645	COG1045	serine acetyltransferase
DI45_RS08660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DI45_RS08705	COG1846	Transcriptional regulator
DI45_RS08725	COG4589	Belongs to the CDS family
DI45_RS08735	COG1862	Preprotein translocase
DI45_RS08745	COG1523	belongs to the glycosyl hydrolase 13 family
DI45_RS08755	COG3842	ATPase activity
DI45_RS08795	COG2190	(PTS) system
DI45_RS08795	COG1263	PTS System
DI45_RS08795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DI45_RS08800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DI45_RS08815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DI45_RS08820	COG0512	Glutamine amidotransferase of anthranilate synthase
DI45_RS08825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DI45_RS08860	COG0601	transmembrane transport
DI45_RS08870	COG1122	ATPase activity
DI45_RS08890	COG0803	Belongs to the bacterial solute-binding protein 9 family
DI45_RS08925	COG3711	transcriptional antiterminator
DI45_RS08935	COG3942	CHAP domain
DI45_RS08935	COG1705	Flagellar rod assembly protein muramidase FlgJ
DI45_RS08940	COG2205	protein histidine kinase activity
DI45_RS08945	COG0745	RESPONSE REGULATOR receiver
DI45_RS08950	COG0577	efflux transmembrane transporter activity
DI45_RS08955	COG1136	(ABC) transporter
DI45_RS09015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DI45_RS09030	COG1882	Formate acetyltransferase
DI45_RS09035	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DI45_RS09040	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DI45_RS09045	COG1447	Phosphotransferase system cellobiose-specific component IIA
DI45_RS09050	COG2390	Transcriptional regulator
DI45_RS09055	COG1349	DNA-binding transcription factor activity
DI45_RS09060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DI45_RS09075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DI45_RS09090	COG0564	pseudouridine synthase activity
DI45_RS09120	COG0542	response to heat
DI45_RS09125	COG4463	regulation of RNA biosynthetic process
DI45_RS09140	COG5433	transposase activity
DI45_RS09150	COG0450	alkyl hydroperoxide reductase
DI45_RS09165	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DI45_RS09175	COG3404	Formiminotransferase-cyclodeaminase
DI45_RS09190	COG0531	amino acid
DI45_RS09210	COG5433	transposase activity
DI45_RS09230	COG3590	peptidase
DI45_RS09235	COG0366	Alpha amylase catalytic
DI45_RS09240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DI45_RS09240	COG1263	PTS System
DI45_RS09255	COG2514	catechol 2,3-dioxygenase activity
DI45_RS09265	COG0602	queuosine metabolic process
DI45_RS09280	COG1328	CTP reductase activity
DI45_RS09315	COG1393	Belongs to the ArsC family
DI45_RS09330	COG0519	Catalyzes the synthesis of GMP from XMP
DI45_RS09375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DI45_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DI45_RS09385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DI45_RS09475	COG1511	domain protein
DI45_RS09495	COG0305	Participates in initiation and elongation during chromosome replication
DI45_RS09525	COG1760	l-serine dehydratase
DI45_RS09530	COG1760	l-serine dehydratase
DI45_RS09535	COG0741	lytic transglycosylase activity
DI45_RS09540	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DI45_RS09555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DI45_RS09565	COG0612	Peptidase, M16
DI45_RS09585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DI45_RS09605	COG0516	GMP reductase activity
DI45_RS09605	COG0517	IMP dehydrogenase activity
DI45_RS09615	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
DI45_RS09620	COG0488	(ABC) transporter
DI45_RS09655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain