locus-tag	class	description
A4265_RS00010	COG0592	DNA-directed DNA polymerase activity
A4265_RS00020	COG0012	GTP binding
A4265_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A4265_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A4265_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A4265_RS00065	COG0531	amino acid
A4265_RS00110	COG3942	CHAP domain
A4265_RS00130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
A4265_RS00140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A4265_RS00155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A4265_RS00175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A4265_RS00200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A4265_RS00215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A4265_RS00230	COG1012	belongs to the aldehyde dehydrogenase family
A4265_RS00230	COG1454	alcohol dehydrogenase
A4265_RS00235	COG1064	alcohol dehydrogenase
A4265_RS00240	COG0534	Mate efflux family protein
A4265_RS00350	COG0201	protein transport
A4265_RS00470	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
A4265_RS00495	COG1121	(ABC) transporter
A4265_RS00500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A4265_RS00510	COG0582	viral genome integration into host DNA
A4265_RS00625	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A4265_RS00645	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A4265_RS00650	COG1459	type II secretion system
A4265_RS00655	COG4537	Required for transformation and DNA binding
A4265_RS00695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
A4265_RS00700	COG1363	Peptidase, m42
A4265_RS00715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A4265_RS00720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A4265_RS00735	COG1428	Deoxynucleoside kinase
A4265_RS00740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A4265_RS00770	COG4509	Sortase family
A4265_RS00795	COG2031	fatty acid transporter
A4265_RS00810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A4265_RS00825	COG0251	oxidation-reduction process
A4265_RS00840	COG1269	ATP hydrolysis coupled proton transport
A4265_RS00845	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
A4265_RS00855	COG1527	subunit (C
A4265_RS00860	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
A4265_RS00895	COG1744	ABC transporter substrate-binding protein PnrA-like
A4265_RS00950	COG0626	cystathionine gamma-synthase activity
A4265_RS00980	COG3623	hexulose-6-phosphate isomerase
A4265_RS01005	COG3448	diguanylate cyclase activity
A4265_RS01005	COG4175	Glycine betaine
A4265_RS01015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4265_RS01015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
A4265_RS01035	COG3969	phosphoadenosine phosphosulfate
A4265_RS01040	COG1475	DNA binding
A4265_RS01050	COG2801	Transposase and inactivated derivatives
A4265_RS01065	COG0157	Belongs to the NadC ModD family
A4265_RS01070	COG2801	Transposase and inactivated derivatives
A4265_RS01095	COG1268	BioY protein
A4265_RS01100	COG1234	tRNA 3'-trailer cleavage
A4265_RS01135	COG0705	Rhomboid family
A4265_RS01135	COG0457	Tetratricopeptide repeat
A4265_RS01155	COG1132	(ABC) transporter
A4265_RS01160	COG1132	(ABC) transporter
A4265_RS01170	COG0756	dUTP diphosphatase activity
A4265_RS01200	COG3290	protein histidine kinase activity
A4265_RS01225	COG1847	R3H domain protein
A4265_RS01245	COG1175	transmembrane transport
A4265_RS01250	COG0395	ABC-type sugar transport system, permease component
A4265_RS01260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A4265_RS01275	COG0084	hydrolase, TatD family'
A4265_RS01300	COG1564	THIamine pyrophosphokinase
A4265_RS01315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A4265_RS01350	COG0765	amino acid transport
A4265_RS01370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A4265_RS01380	COG0719	Fe-S assembly protein
A4265_RS01385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A4265_RS01400	COG1686	Belongs to the peptidase S11 family
A4265_RS01405	COG1686	Belongs to the peptidase S11 family
A4265_RS01410	COG4166	transmembrane transport
A4265_RS01415	COG0601	transmembrane transport
A4265_RS01420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A4265_RS01425	COG0444	Belongs to the ABC transporter superfamily
A4265_RS01435	COG2801	Transposase and inactivated derivatives
A4265_RS01490	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
A4265_RS01495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
A4265_RS01500	COG1534	Rna-binding protein
A4265_RS01510	COG1713	HD superfamily hydrolase involved in NAD metabolism
A4265_RS01515	COG0799	negative regulation of ribosome biogenesis
A4265_RS01520	COG2226	methyltransferase
A4265_RS01540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4265_RS01545	COG1464	Belongs to the NlpA lipoprotein family
A4265_RS01560	COG1114	Component of the transport system for branched-chain amino acids
A4265_RS01570	COG0569	domain protein
A4265_RS01575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A4265_RS01585	COG1704	LemA family
A4265_RS01600	COG0745	RESPONSE REGULATOR receiver
A4265_RS01630	COG1484	DNA-dependent DNA replication
A4265_RS01640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A4265_RS01660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A4265_RS01675	COG1254	Belongs to the acylphosphatase family
A4265_RS01680	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A4265_RS01735	COG1187	pseudouridine synthase activity
A4265_RS01750	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
A4265_RS01755	COG0671	phosphoesterase, PA-phosphatase related
A4265_RS01760	COG1242	4 iron, 4 sulfur cluster binding
A4265_RS01765	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
A4265_RS01770	COG1253	flavin adenine dinucleotide binding
A4265_RS01775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A4265_RS01790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4265_RS01795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A4265_RS01800	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A4265_RS01805	COG1120	ATPase activity
A4265_RS01815	COG2244	polysaccharide biosynthetic process
A4265_RS01845	COG0470	DNA polymerase III
A4265_RS01875	COG1393	Belongs to the ArsC family
A4265_RS01880	COG0708	Exodeoxyribonuclease III
A4265_RS01890	COG1304	FMN binding
A4265_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
A4265_RS01975	COG0673	inositol 2-dehydrogenase activity
A4265_RS01990	COG0494	nUDIX hydrolase
A4265_RS02000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A4265_RS02090	COG1702	phosphate starvation-inducible protein PhoH
A4265_RS02095	COG1573	uracil-dna glycosylase
A4265_RS02105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
A4265_RS02130	COG2274	protein secretion by the type I secretion system
A4265_RS02135	COG2274	protein secretion by the type I secretion system
A4265_RS02140	COG2274	protein secretion by the type I secretion system
A4265_RS02170	COG2801	Transposase and inactivated derivatives
A4265_RS02175	COG2801	Transposase and inactivated derivatives
A4265_RS02185	COG3279	Response regulator of the LytR AlgR family
A4265_RS02205	COG2274	protein secretion by the type I secretion system
A4265_RS02300	COG0433	COG0433 Predicted ATPase
A4265_RS02305	COG2814	Major facilitator Superfamily
A4265_RS02320	COG0557	exoribonuclease II activity
A4265_RS02350	COG0463	Glycosyl transferase, family 2
A4265_RS02360	COG0778	Nitroreductase
A4265_RS02365	COG0006	proline dipeptidase activity
A4265_RS02370	COG1609	Transcriptional regulator
A4265_RS02380	COG0438	transferase activity, transferring glycosyl groups
A4265_RS02395	COG4555	ABC transporter
A4265_RS02415	COG0183	Belongs to the thiolase family
A4265_RS02430	COG0745	RESPONSE REGULATOR receiver
A4265_RS02435	COG5002	protein histidine kinase activity
A4265_RS02440	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
A4265_RS02450	COG1196	nuclear chromosome segregation
A4265_RS02460	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
A4265_RS02550	COG4695	Portal protein
A4265_RS02565	COG1619	proteins homologs of microcin C7 resistance protein MccF
A4265_RS02585	COG0561	phosphatase activity
A4265_RS02590	COG0561	phosphatase activity
A4265_RS02595	COG0552	protein localization to endoplasmic reticulum
A4265_RS02600	COG0477	Major facilitator Superfamily
A4265_RS02605	COG3711	transcriptional antiterminator
A4265_RS02610	COG2190	(PTS) system
A4265_RS02610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4265_RS02610	COG1263	PTS System
A4265_RS02620	COG3689	TIGRFAM TIGR03943 family protein
A4265_RS02625	COG0701	Predicted permease
A4265_RS02635	COG2183	response to ionizing radiation
A4265_RS02680	COG0826	peptidase U32
A4265_RS02685	COG4443	Transcriptional Coactivator p15 (PC4)
A4265_RS02730	COG0386	Belongs to the glutathione peroxidase family
A4265_RS02735	COG1164	Oligoendopeptidase f
A4265_RS02745	COG0772	Belongs to the SEDS family
A4265_RS02780	COG1078	dGTPase activity
A4265_RS02795	COG1609	Transcriptional regulator
A4265_RS02805	COG3716	PTS system mannose fructose sorbose family IID component
A4265_RS02810	COG3715	PTS system
A4265_RS02815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4265_RS02830	COG1028	Short-chain dehydrogenase reductase Sdr
A4265_RS02845	COG0800	Aldolase
A4265_RS02850	COG0546	phosphoglycolate phosphatase activity
A4265_RS02865	COG2884	Cell division ATP-binding protein ftsE
A4265_RS02870	COG2177	Part of the ABC transporter FtsEX involved in
A4265_RS02885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A4265_RS02885	COG1199	ATP-dependent helicase activity
A4265_RS02890	COG0436	Aminotransferase
A4265_RS02925	COG2188	Transcriptional regulator
A4265_RS02930	COG2222	sugar isomerase
A4265_RS02940	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
A4265_RS02945	COG0716	FMN binding
A4265_RS02955	COG0038	chloride channel
A4265_RS03050	COG1131	(ABC) transporter
A4265_RS03075	COG4708	membrane
A4265_RS03085	COG1597	lipid kinase activity
A4265_RS03170	COG0577	efflux transmembrane transporter activity
A4265_RS03180	COG2321	neutral zinc metallopeptidase
A4265_RS03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4265_RS03205	COG1970	mechanosensitive ion channel activity
A4265_RS03210	COG0358	DNA primase activity
A4265_RS03215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
A4265_RS03220	COG2151	metal-sulfur cluster biosynthetic enzyme
A4265_RS03265	COG1216	Glycosyl transferase, family 2
A4265_RS03325	COG1368	sulfuric ester hydrolase activity
A4265_RS03330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
A4265_RS03350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A4265_RS03355	COG0285	dihydrofolate synthase activity
A4265_RS03365	COG1104	cysteine desulfurase activity
A4265_RS03390	COG0211	Belongs to the bacterial ribosomal protein bL27 family
A4265_RS03400	COG0583	DNA-binding transcription factor activity
A4265_RS03410	COG0564	pseudouridine synthase activity
A4265_RS03445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A4265_RS03450	COG1136	(ABC) transporter
A4265_RS03455	COG0577	efflux transmembrane transporter activity
A4265_RS03460	COG0584	glycerophosphoryl diester phosphodiesterase
A4265_RS03470	COG1837	Belongs to the UPF0109 family
A4265_RS03520	COG1349	DNA-binding transcription factor activity
A4265_RS03525	COG1105	Belongs to the carbohydrate kinase PfkB family
A4265_RS03530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4265_RS03530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4265_RS03530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
A4265_RS03535	COG1705	Flagellar rod assembly protein muramidase FlgJ
A4265_RS03535	COG1388	LysM domain
A4265_RS03540	COG1388	LysM domain
A4265_RS03540	COG1705	Flagellar rod assembly protein muramidase FlgJ
A4265_RS03560	COG0105	UTP biosynthetic process
A4265_RS03580	COG0488	(ABC) transporter
A4265_RS03590	COG0242	peptide deformylase activity
A4265_RS03595	COG0737	Belongs to the 5'-nucleotidase family
A4265_RS03600	COG2357	RelA SpoT domain protein
A4265_RS03605	COG0745	RESPONSE REGULATOR receiver
A4265_RS03640	COG3425	synthase
A4265_RS03650	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
A4265_RS03695	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A4265_RS03710	COG0583	DNA-binding transcription factor activity
A4265_RS03735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4265_RS03740	COG0765	amino acid transport
A4265_RS03760	COG0187	DNA topoisomerase II activity
A4265_RS03775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A4265_RS03795	COG0539	negative regulation of cytoplasmic translation
A4265_RS03810	COG2801	Transposase and inactivated derivatives
A4265_RS03905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A4265_RS03910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
A4265_RS03920	COG0300	oxidoreductase activity
A4265_RS03925	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
A4265_RS03925	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A4265_RS03940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A4265_RS03945	COG2384	SAM-dependent methyltransferase
A4265_RS03955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A4265_RS03960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A4265_RS03970	COG1088	dTDP-glucose 4,6-dehydratase activity
A4265_RS03975	COG1051	belongs to the nudix hydrolase family
A4265_RS03980	COG0628	permease
A4265_RS03985	COG0457	Tetratricopeptide repeat
A4265_RS03990	COG1293	RNA-binding protein homologous to eukaryotic snRNP
A4265_RS04010	COG1129	ABC transporter
A4265_RS04030	COG0488	(ABC) transporter
A4265_RS04035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A4265_RS04040	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4265_RS04040	COG0022	dehydrogenase e1 component
A4265_RS04045	COG0508	dehydrogenase complex catalyzes the overall conversion of
A4265_RS04065	COG5492	domain, Protein
A4265_RS04070	COG0095	Lipoate-protein ligase
A4265_RS04075	COG3442	glutamine amidotransferase
A4265_RS04080	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A4265_RS04085	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
A4265_RS04105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A4265_RS04115	COG0647	UMP catabolic process
A4265_RS04185	COG3715	PTS system
A4265_RS04190	COG3716	PTS system mannose fructose sorbose family IID component
A4265_RS04195	COG2972	Histidine kinase
A4265_RS04200	COG2207	Transcriptional regulator
A4265_RS04200	COG4753	response regulator
A4265_RS04210	COG1012	belongs to the aldehyde dehydrogenase family
A4265_RS04225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A4265_RS04295	COG1131	(ABC) transporter
A4265_RS04310	COG1396	sequence-specific DNA binding
A4265_RS04345	COG0285	dihydrofolate synthase activity
A4265_RS04365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A4265_RS04380	COG1176	ABC-type spermidine putrescine transport system, permease component I
A4265_RS04385	COG1177	transmembrane transport
A4265_RS04395	COG4565	transcriptional regulatory protein
A4265_RS04400	COG3290	protein histidine kinase activity
A4265_RS04405	COG3493	citrate carrier protein
A4265_RS04420	COG3700	Belongs to the class B bacterial acid phosphatase family
A4265_RS04425	COG0038	chloride channel
A4265_RS04435	COG0628	permease
A4265_RS04445	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A4265_RS04460	COG1104	cysteine desulfurase activity
A4265_RS04475	COG2357	RelA SpoT domain protein
A4265_RS04485	COG0564	pseudouridine synthase activity
A4265_RS04490	COG0280	phosphate acetyltransferase
A4265_RS04495	COG4221	oxidoreductase activity
A4265_RS04510	COG1174	glycine betaine transport
A4265_RS04525	COG2233	PERMEase
A4265_RS04550	COG2890	protein-(glutamine-N5) methyltransferase activity
A4265_RS04580	COG1132	(ABC) transporter
A4265_RS04585	COG1132	(ABC) transporter
A4265_RS04605	COG3764	Sortase (surface protein transpeptidase)
A4265_RS04610	COG0346	lactoylglutathione lyase activity
A4265_RS04630	COG1272	protein, Hemolysin III
A4265_RS04650	COG0758	DNA mediated transformation
A4265_RS04655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A4265_RS04675	COG0511	ligase activity, forming carbon-carbon bonds
A4265_RS04680	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A4265_RS04695	COG2851	Citrate transporter
A4265_RS04705	COG0511	ligase activity, forming carbon-carbon bonds
A4265_RS04710	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A4265_RS04740	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
A4265_RS04760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A4265_RS04770	COG2188	Transcriptional regulator
A4265_RS04790	COG0488	(ABC) transporter
A4265_RS04800	COG0352	thiamine-phosphate diphosphorylase activity
A4265_RS04800	COG0351	phosphomethylpyrimidine kinase
A4265_RS04805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A4265_RS04810	COG1328	CTP reductase activity
A4265_RS04810	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
A4265_RS04815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A4265_RS04845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A4265_RS04855	COG0095	Lipoate-protein ligase
A4265_RS04865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A4265_RS04870	COG4684	Psort location CytoplasmicMembrane, score
A4265_RS04875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4265_RS04880	COG1079	Belongs to the binding-protein-dependent transport system permease family
A4265_RS04885	COG4603	Belongs to the binding-protein-dependent transport system permease family
A4265_RS04890	COG3845	ABC transporter
A4265_RS04895	COG1744	ABC transporter substrate-binding protein PnrA-like
A4265_RS04900	COG0295	cytidine deaminase activity
A4265_RS04905	COG2813	Specifically methylates the guanine in position
A4265_RS04920	COG5002	protein histidine kinase activity
A4265_RS04925	COG0745	RESPONSE REGULATOR receiver
A4265_RS04940	COG0704	Plays a role in the regulation of phosphate uptake
A4265_RS04955	COG0581	inorganic phosphate transmembrane transporter activity
A4265_RS04960	COG0573	inorganic phosphate transmembrane transporter activity
A4265_RS04970	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A4265_RS04970	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A4265_RS04975	COG0483	inositol monophosphate 1-phosphatase activity
A4265_RS04990	COG0196	riboflavin kinase activity
A4265_RS05070	COG1115	amino acid carrier protein
A4265_RS05075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A4265_RS05085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4265_RS05090	COG1126	abc transporter atp-binding protein
A4265_RS05095	COG0765	amino acid transport
A4265_RS05100	COG2824	Alkylphosphonate utilization operon protein PhnA
A4265_RS05115	COG0469	pyruvate kinase activity
A4265_RS05130	COG1725	Transcriptional regulator
A4265_RS05135	COG1131	(ABC) transporter
A4265_RS05160	COG0058	SHG alpha-glucan phosphorylase activity
A4265_RS05165	COG1640	4-alpha-glucanotransferase
A4265_RS05170	COG1609	Transcriptional regulator
A4265_RS05175	COG2182	Extracellular solute-binding protein
A4265_RS05180	COG1175	transmembrane transport
A4265_RS05185	COG3833	ABC-type maltose transport systems, permease component
A4265_RS05200	COG3833	ABC-type maltose transport systems, permease component
A4265_RS05205	COG1175	transmembrane transport
A4265_RS05215	COG0366	Alpha amylase catalytic
A4265_RS05220	COG2182	Extracellular solute-binding protein
A4265_RS05230	COG0657	acetylesterase activity
A4265_RS05235	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
A4265_RS05245	COG1696	Membrane protein involved in D-alanine export
A4265_RS05265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A4265_RS05270	COG1126	abc transporter atp-binding protein
A4265_RS05275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A4265_RS05285	COG1447	Phosphotransferase system cellobiose-specific component IIA
A4265_RS05295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
A4265_RS05295	COG3711	transcriptional antiterminator
A4265_RS05305	COG2723	6-phospho-beta-galactosidase activity
A4265_RS05335	COG2801	Transposase and inactivated derivatives
A4265_RS05340	COG0157	Belongs to the NadC ModD family
A4265_RS05360	COG1187	pseudouridine synthase activity
A4265_RS05370	COG2814	Major facilitator Superfamily
A4265_RS05420	COG4109	DRTGG domain
A4265_RS05425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A4265_RS05450	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
A4265_RS05450	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
A4265_RS05460	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A4265_RS05465	COG1956	GAF domain-containing protein
A4265_RS05485	COG0513	Belongs to the DEAD box helicase family
A4265_RS05490	COG0726	polysaccharide deacetylase
A4265_RS05510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A4265_RS05515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A4265_RS05535	COG2801	Transposase and inactivated derivatives
A4265_RS05550	COG1476	TRANSCRIPTIONal
A4265_RS05565	COG4122	O-methyltransferase activity
A4265_RS05570	COG2223	nitrite transmembrane transporter activity
A4265_RS05585	COG1187	pseudouridine synthase activity
A4265_RS05630	COG0658	competence protein
A4265_RS05630	COG2333	competence protein COMEC
A4265_RS05635	COG1596	polysaccharide export
A4265_RS05635	COG1555	photosystem II stabilization
A4265_RS05640	COG0204	Acyl-transferase
A4265_RS05645	COG2890	protein-(glutamine-N5) methyltransferase activity
A4265_RS05660	COG0513	Belongs to the DEAD box helicase family
A4265_RS05680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A4265_RS05695	COG0768	penicillin binding
A4265_RS05700	COG2116	formate transmembrane transporter activity
A4265_RS05710	COG1827	regulation of RNA biosynthetic process
A4265_RS05725	COG2217	Heavy metal translocating P-type atpase
A4265_RS05740	COG2755	lipolytic protein G-D-S-L family
A4265_RS05755	COG0497	DNA recombination
A4265_RS05760	COG1438	arginine binding
A4265_RS05765	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
A4265_RS05790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A4265_RS05795	COG0415	Belongs to the DNA photolyase family
A4265_RS05805	COG0765	amino acid transport
A4265_RS05810	COG4703	Protein of unknown function (DUF1797)
A4265_RS05815	COG0542	response to heat
A4265_RS05820	COG0494	nUDIX hydrolase
A4265_RS05835	COG3599	regulation of cell shape
A4265_RS05840	COG2302	S4 RNA-binding domain
A4265_RS05855	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
A4265_RS05890	COG1217	gtp-binding protein TYPA
A4265_RS05895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A4265_RS05900	COG1940	carbohydrate kinase activity
A4265_RS05910	COG0783	Belongs to the Dps family
A4265_RS05925	COG4470	Protein conserved in bacteria
A4265_RS05930	COG1609	Transcriptional regulator
A4265_RS05935	COG3480	Lon protease (S16) C-terminal proteolytic domain
A4265_RS05945	COG0742	ribosomal rna small subunit methyltransferase
A4265_RS05955	COG0549	Belongs to the carbamate kinase family
A4265_RS05960	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A4265_RS05965	COG1288	antiporter activity
A4265_RS05980	COG2235	arginine
A4265_RS06005	COG2972	Histidine kinase
A4265_RS06020	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
A4265_RS06025	COG0785	Cytochrome C biogenesis protein
A4265_RS06035	COG0673	inositol 2-dehydrogenase activity
A4265_RS06085	COG1605	Chorismate mutase
A4265_RS06085	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
A4265_RS06105	COG2226	methyltransferase
A4265_RS06115	COG3250	beta-galactosidase activity
A4265_RS06120	COG2207	Transcriptional regulator
A4265_RS06120	COG4753	response regulator
A4265_RS06125	COG2972	Histidine kinase
A4265_RS06135	COG1653	transport
A4265_RS06140	COG0395	ABC-type sugar transport system, permease component
A4265_RS06145	COG1175	transmembrane transport
A4265_RS06150	COG1940	carbohydrate kinase activity
A4265_RS06155	COG2723	6-phospho-beta-galactosidase activity
A4265_RS06160	COG3525	Glycosyl hydrolase, family 20, catalytic domain
A4265_RS06175	COG0383	alpha-mannosidase activity
A4265_RS06280	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
A4265_RS06285	COG1739	Uncharacterized protein family UPF0029
A4265_RS06295	COG1185	polyribonucleotide nucleotidyltransferase activity
A4265_RS06305	COG2197	response regulator
A4265_RS06310	COG4585	Histidine kinase
A4265_RS06320	COG0515	serine threonine protein kinase
A4265_RS06320	COG2815	serine threonine protein kinase
A4265_RS06330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A4265_RS06330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A4265_RS06340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A4265_RS06360	COG0583	DNA-binding transcription factor activity
A4265_RS06365	COG0183	Belongs to the thiolase family
A4265_RS06370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A4265_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
A4265_RS06400	COG0116	Belongs to the methyltransferase superfamily
A4265_RS06425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A4265_RS06430	COG3579	cysteine-type endopeptidase activity
A4265_RS06440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
A4265_RS06445	COG1113	amino acid transport
A4265_RS06450	COG0492	ferredoxin-NADP+ reductase activity
A4265_RS06460	COG1126	abc transporter atp-binding protein
A4265_RS06470	COG0513	Belongs to the DEAD box helicase family
A4265_RS06480	COG0768	penicillin binding
A4265_RS06520	COG1131	(ABC) transporter
A4265_RS06545	COG0446	pyridine nucleotide-disulphide oxidoreductase
A4265_RS06550	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A4265_RS06590	COG1755	Isoprenylcysteine carboxyl methyltransferase
A4265_RS06595	COG0656	L-ascorbic acid biosynthetic process
A4265_RS06605	COG1283	sodium-dependent phosphate transmembrane transporter activity
A4265_RS06625	COG0561	phosphatase activity
A4265_RS06630	COG2860	membrane
A4265_RS06660	COG3775	system Galactitol-specific IIC component
A4265_RS06690	COG2217	Heavy metal translocating P-type atpase
A4265_RS06720	COG2740	Nucleic-acid-binding protein implicated in transcription termination
A4265_RS06725	COG0195	Participates in both transcription termination and antitermination
A4265_RS06750	COG4473	ABC transporter
A4265_RS06755	COG1131	(ABC) transporter
A4265_RS06760	COG0537	adenosine 5'-monophosphoramidase activity
A4265_RS06770	COG1316	TRANSCRIPTIONal
A4265_RS06780	COG0802	atpase or kinase
A4265_RS06785	COG2252	PERMEase
A4265_RS06790	COG0561	phosphatase activity
A4265_RS06800	COG3715	PTS system
A4265_RS06805	COG3716	PTS system mannose fructose sorbose family IID component
A4265_RS06830	COG0439	Biotin carboxylase
A4265_RS06845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
A4265_RS06850	COG1028	Short-chain dehydrogenase reductase Sdr
A4265_RS06855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A4265_RS06880	COG1024	Enoyl-CoA hydratase
A4265_RS06915	COG0588	phosphoglycerate mutase activity
A4265_RS06920	COG2261	transglycosylase associated protein
A4265_RS06945	COG0574	Belongs to the PEP-utilizing enzyme family
A4265_RS06945	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A4265_RS06955	COG1335	isochorismatase
A4265_RS06965	COG0436	Aminotransferase
A4265_RS06975	COG0561	phosphatase activity
A4265_RS06980	COG0252	asparaginase activity
A4265_RS06995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A4265_RS07005	COG1129	ABC transporter
A4265_RS07020	COG1132	(ABC) transporter
A4265_RS07025	COG4988	ABC transporter
A4265_RS07030	COG1120	ATPase activity
A4265_RS07050	COG3942	CHAP domain
A4265_RS07050	COG1388	LysM domain
A4265_RS07070	COG1482	cell wall glycoprotein biosynthetic process
A4265_RS07075	COG1940	carbohydrate kinase activity
A4265_RS07085	COG1263	PTS System
A4265_RS07085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4265_RS07085	COG2190	(PTS) system
A4265_RS07090	COG1621	beta-fructofuranosidase activity
A4265_RS07095	COG1609	Transcriptional regulator
A4265_RS07115	COG2131	deaminase
A4265_RS07120	COG0006	proline dipeptidase activity
A4265_RS07160	COG1194	a g-specific adenine glycosylase
A4265_RS07165	COG3620	sequence-specific DNA binding
A4265_RS07170	COG3118	belongs to the thioredoxin family
A4265_RS07200	COG0681	Belongs to the peptidase S26 family
A4265_RS07205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A4265_RS07220	COG1882	Formate acetyltransferase
A4265_RS07225	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A4265_RS07240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
A4265_RS07250	COG2814	Major facilitator Superfamily
A4265_RS07255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A4265_RS07280	COG0789	Transcriptional regulator
A4265_RS07295	COG2081	HI0933 family
A4265_RS07305	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
A4265_RS07310	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A4265_RS07330	COG0456	acetyltransferase
A4265_RS07335	COG1214	PFAM Peptidase M22, glycoprotease
A4265_RS07350	COG0174	glutamine synthetase
A4265_RS07355	COG0789	Transcriptional regulator
A4265_RS07370	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
A4265_RS07425	COG0668	transmembrane transport
A4265_RS07435	COG4720	Psort location CytoplasmicMembrane, score
A4265_RS07440	COG0351	phosphomethylpyrimidine kinase
A4265_RS07490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
A4265_RS07520	COG0577	efflux transmembrane transporter activity
A4265_RS07525	COG1136	(ABC) transporter
A4265_RS07550	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A4265_RS07550	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A4265_RS07555	COG1447	Phosphotransferase system cellobiose-specific component IIA
A4265_RS07600	COG4974	Belongs to the 'phage' integrase family
A4265_RS07610	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A4265_RS07615	COG1476	TRANSCRIPTIONal
A4265_RS07635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A4265_RS07645	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
A4265_RS07665	COG1045	serine acetyltransferase
A4265_RS07680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A4265_RS07695	COG3711	transcriptional antiterminator
A4265_RS07730	COG1846	Transcriptional regulator
A4265_RS07750	COG4589	Belongs to the CDS family
A4265_RS07760	COG1862	Preprotein translocase
A4265_RS07770	COG1523	belongs to the glycosyl hydrolase 13 family
A4265_RS07785	COG3842	ATPase activity
A4265_RS07825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4265_RS07825	COG1263	PTS System
A4265_RS07825	COG2190	(PTS) system
A4265_RS07830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A4265_RS07845	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A4265_RS07850	COG0512	Glutamine amidotransferase of anthranilate synthase
A4265_RS07855	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A4265_RS07895	COG0601	transmembrane transport
A4265_RS07905	COG1122	ATPase activity
A4265_RS07925	COG0803	Belongs to the bacterial solute-binding protein 9 family
A4265_RS07955	COG3711	transcriptional antiterminator
A4265_RS07970	COG1705	Flagellar rod assembly protein muramidase FlgJ
A4265_RS07970	COG3942	CHAP domain
A4265_RS07975	COG2205	protein histidine kinase activity
A4265_RS07980	COG0745	RESPONSE REGULATOR receiver
A4265_RS07985	COG0577	efflux transmembrane transporter activity
A4265_RS07990	COG1136	(ABC) transporter
A4265_RS08055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A4265_RS08070	COG1882	Formate acetyltransferase
A4265_RS08075	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A4265_RS08080	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
A4265_RS08085	COG1447	Phosphotransferase system cellobiose-specific component IIA
A4265_RS08090	COG2390	Transcriptional regulator
A4265_RS08095	COG1349	DNA-binding transcription factor activity
A4265_RS08100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
A4265_RS08120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A4265_RS08135	COG0564	pseudouridine synthase activity
A4265_RS08170	COG0542	response to heat
A4265_RS08175	COG4463	regulation of RNA biosynthetic process
A4265_RS08190	COG0450	alkyl hydroperoxide reductase
A4265_RS08205	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
A4265_RS08215	COG3404	Formiminotransferase-cyclodeaminase
A4265_RS08230	COG0531	amino acid
A4265_RS08260	COG3590	peptidase
A4265_RS08265	COG0366	Alpha amylase catalytic
A4265_RS08270	COG1263	PTS System
A4265_RS08270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
A4265_RS08275	COG2188	Transcriptional regulator
A4265_RS08285	COG1733	regulation of RNA biosynthetic process
A4265_RS08290	COG2514	catechol 2,3-dioxygenase activity
A4265_RS08300	COG0602	queuosine metabolic process
A4265_RS08315	COG1328	CTP reductase activity
A4265_RS08340	COG1393	Belongs to the ArsC family
A4265_RS08365	COG2814	Major facilitator Superfamily
A4265_RS08375	COG0582	viral genome integration into host DNA
A4265_RS08380	COG3645	SOS response
A4265_RS08535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A4265_RS08540	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A4265_RS08545	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A4265_RS08630	COG1511	domain protein
A4265_RS08650	COG0305	Participates in initiation and elongation during chromosome replication
A4265_RS08680	COG1760	l-serine dehydratase
A4265_RS08685	COG1760	l-serine dehydratase
A4265_RS08690	COG0741	lytic transglycosylase activity
A4265_RS08695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A4265_RS08710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A4265_RS08720	COG0612	Peptidase, M16
A4265_RS08735	COG5433	transposase activity
A4265_RS08740	COG1215	transferase activity, transferring glycosyl groups
A4265_RS08755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A4265_RS08775	COG0516	GMP reductase activity
A4265_RS08775	COG0517	IMP dehydrogenase activity
A4265_RS08785	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
A4265_RS08790	COG0488	(ABC) transporter
A4265_RS08825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A4265_RS08830	COG1475	DNA binding