locus-tag	class	description
D0Z58_RS00010	COG0592	DNA-directed DNA polymerase activity
D0Z58_RS00020	COG0012	GTP binding
D0Z58_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0Z58_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0Z58_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0Z58_RS00065	COG0531	amino acid
D0Z58_RS00245	COG3942	CHAP domain
D0Z58_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0Z58_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0Z58_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0Z58_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0Z58_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0Z58_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0Z58_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
D0Z58_RS00355	COG1454	alcohol dehydrogenase
D0Z58_RS00360	COG1064	alcohol dehydrogenase
D0Z58_RS00365	COG0534	Mate efflux family protein
D0Z58_RS00475	COG0201	protein transport
D0Z58_RS00620	COG1121	(ABC) transporter
D0Z58_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0Z58_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0Z58_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0Z58_RS00665	COG1459	type II secretion system
D0Z58_RS00670	COG4537	Required for transformation and DNA binding
D0Z58_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0Z58_RS00715	COG1363	Peptidase, m42
D0Z58_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0Z58_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0Z58_RS00745	COG1428	Deoxynucleoside kinase
D0Z58_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0Z58_RS00795	COG4509	Sortase family
D0Z58_RS00820	COG2031	fatty acid transporter
D0Z58_RS00835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0Z58_RS00850	COG0251	oxidation-reduction process
D0Z58_RS00865	COG1269	ATP hydrolysis coupled proton transport
D0Z58_RS00870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0Z58_RS00880	COG1527	subunit (C
D0Z58_RS00885	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
D0Z58_RS00920	COG1744	ABC transporter substrate-binding protein PnrA-like
D0Z58_RS00965	COG0626	cystathionine gamma-synthase activity
D0Z58_RS00995	COG3623	hexulose-6-phosphate isomerase
D0Z58_RS01020	COG3448	diguanylate cyclase activity
D0Z58_RS01020	COG4175	Glycine betaine
D0Z58_RS01030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0Z58_RS01030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0Z58_RS01050	COG3969	phosphoadenosine phosphosulfate
D0Z58_RS01055	COG1475	DNA binding
D0Z58_RS01080	COG0157	Belongs to the NadC ModD family
D0Z58_RS01110	COG1268	BioY protein
D0Z58_RS01115	COG5433	transposase activity
D0Z58_RS01125	COG1234	tRNA 3'-trailer cleavage
D0Z58_RS01160	COG5433	transposase activity
D0Z58_RS01170	COG0457	Tetratricopeptide repeat
D0Z58_RS01170	COG0705	Rhomboid family
D0Z58_RS01190	COG1132	(ABC) transporter
D0Z58_RS01195	COG1132	(ABC) transporter
D0Z58_RS01205	COG0756	dUTP diphosphatase activity
D0Z58_RS01230	COG3290	protein histidine kinase activity
D0Z58_RS01255	COG1847	R3H domain protein
D0Z58_RS01275	COG1175	transmembrane transport
D0Z58_RS01280	COG0395	ABC-type sugar transport system, permease component
D0Z58_RS01290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0Z58_RS01305	COG0084	hydrolase, TatD family'
D0Z58_RS01330	COG1564	THIamine pyrophosphokinase
D0Z58_RS01345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0Z58_RS01385	COG0765	amino acid transport
D0Z58_RS01405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0Z58_RS01415	COG0719	Fe-S assembly protein
D0Z58_RS01420	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0Z58_RS01435	COG1686	Belongs to the peptidase S11 family
D0Z58_RS01440	COG1686	Belongs to the peptidase S11 family
D0Z58_RS01445	COG4166	transmembrane transport
D0Z58_RS01450	COG0601	transmembrane transport
D0Z58_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0Z58_RS01460	COG0444	Belongs to the ABC transporter superfamily
D0Z58_RS01510	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D0Z58_RS01515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0Z58_RS01520	COG1534	Rna-binding protein
D0Z58_RS01530	COG1713	HD superfamily hydrolase involved in NAD metabolism
D0Z58_RS01535	COG0799	negative regulation of ribosome biogenesis
D0Z58_RS01540	COG2226	methyltransferase
D0Z58_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0Z58_RS01565	COG1464	Belongs to the NlpA lipoprotein family
D0Z58_RS01580	COG1114	Component of the transport system for branched-chain amino acids
D0Z58_RS01590	COG0569	domain protein
D0Z58_RS01595	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0Z58_RS01605	COG1704	LemA family
D0Z58_RS01620	COG0745	RESPONSE REGULATOR receiver
D0Z58_RS01640	COG1484	DNA-dependent DNA replication
D0Z58_RS01650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0Z58_RS01670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0Z58_RS01685	COG1254	Belongs to the acylphosphatase family
D0Z58_RS01690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0Z58_RS01745	COG1187	pseudouridine synthase activity
D0Z58_RS01760	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D0Z58_RS01765	COG0671	phosphoesterase, PA-phosphatase related
D0Z58_RS01770	COG1242	4 iron, 4 sulfur cluster binding
D0Z58_RS01775	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D0Z58_RS01780	COG1253	flavin adenine dinucleotide binding
D0Z58_RS01785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0Z58_RS01800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0Z58_RS01805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0Z58_RS01810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0Z58_RS01815	COG1120	ATPase activity
D0Z58_RS01825	COG2244	polysaccharide biosynthetic process
D0Z58_RS01850	COG5433	transposase activity
D0Z58_RS01860	COG0470	DNA polymerase III
D0Z58_RS01890	COG1393	Belongs to the ArsC family
D0Z58_RS01895	COG0708	Exodeoxyribonuclease III
D0Z58_RS01905	COG1304	FMN binding
D0Z58_RS01995	COG1028	Short-chain dehydrogenase reductase Sdr
D0Z58_RS02000	COG0673	inositol 2-dehydrogenase activity
D0Z58_RS02015	COG0494	nUDIX hydrolase
D0Z58_RS02025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0Z58_RS02090	COG2996	Protein conserved in bacteria
D0Z58_RS02115	COG1702	phosphate starvation-inducible protein PhoH
D0Z58_RS02120	COG1573	uracil-dna glycosylase
D0Z58_RS02130	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0Z58_RS02220	COG0433	COG0433 Predicted ATPase
D0Z58_RS02225	COG2814	Major facilitator Superfamily
D0Z58_RS02240	COG0557	exoribonuclease II activity
D0Z58_RS02270	COG0463	Glycosyl transferase, family 2
D0Z58_RS02280	COG0778	Nitroreductase
D0Z58_RS02285	COG0006	proline dipeptidase activity
D0Z58_RS02290	COG1609	Transcriptional regulator
D0Z58_RS02300	COG0438	transferase activity, transferring glycosyl groups
D0Z58_RS02310	COG4555	ABC transporter
D0Z58_RS02330	COG0183	Belongs to the thiolase family
D0Z58_RS02345	COG0745	RESPONSE REGULATOR receiver
D0Z58_RS02350	COG5002	protein histidine kinase activity
D0Z58_RS02355	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D0Z58_RS02365	COG1196	nuclear chromosome segregation
D0Z58_RS02380	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0Z58_RS02485	COG0561	phosphatase activity
D0Z58_RS02490	COG0552	protein localization to endoplasmic reticulum
D0Z58_RS02495	COG0477	Major facilitator Superfamily
D0Z58_RS02500	COG3711	transcriptional antiterminator
D0Z58_RS02505	COG1263	PTS System
D0Z58_RS02505	COG2190	(PTS) system
D0Z58_RS02505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0Z58_RS02515	COG3689	TIGRFAM TIGR03943 family protein
D0Z58_RS02520	COG0701	Predicted permease
D0Z58_RS02530	COG2183	response to ionizing radiation
D0Z58_RS02575	COG0826	peptidase U32
D0Z58_RS02580	COG4443	Transcriptional Coactivator p15 (PC4)
D0Z58_RS02595	COG0588	phosphoglycerate mutase activity
D0Z58_RS02625	COG0386	Belongs to the glutathione peroxidase family
D0Z58_RS02630	COG1164	Oligoendopeptidase f
D0Z58_RS02640	COG0772	Belongs to the SEDS family
D0Z58_RS02675	COG1078	dGTPase activity
D0Z58_RS02690	COG1609	Transcriptional regulator
D0Z58_RS02700	COG3716	PTS system mannose fructose sorbose family IID component
D0Z58_RS02705	COG3715	PTS system
D0Z58_RS02710	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0Z58_RS02725	COG1028	Short-chain dehydrogenase reductase Sdr
D0Z58_RS02740	COG0800	Aldolase
D0Z58_RS02745	COG0546	phosphoglycolate phosphatase activity
D0Z58_RS02750	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0Z58_RS02760	COG2884	Cell division ATP-binding protein ftsE
D0Z58_RS02765	COG2177	Part of the ABC transporter FtsEX involved in
D0Z58_RS02785	COG0436	Aminotransferase
D0Z58_RS02885	COG1111	helicase
D0Z58_RS02885	COG1205	dead DEAH box helicase
D0Z58_RS02975	COG1598	PFAM Uncharacterised protein family UPF0150
D0Z58_RS03105	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0Z58_RS03130	COG2188	Transcriptional regulator
D0Z58_RS03135	COG2222	sugar isomerase
D0Z58_RS03145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D0Z58_RS03150	COG0716	FMN binding
D0Z58_RS03160	COG0038	chloride channel
D0Z58_RS03255	COG1131	(ABC) transporter
D0Z58_RS03280	COG4708	membrane
D0Z58_RS03290	COG1597	lipid kinase activity
D0Z58_RS03375	COG0577	efflux transmembrane transporter activity
D0Z58_RS03385	COG2321	neutral zinc metallopeptidase
D0Z58_RS03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0Z58_RS03410	COG1970	mechanosensitive ion channel activity
D0Z58_RS03415	COG0358	DNA primase activity
D0Z58_RS03420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0Z58_RS03425	COG2151	metal-sulfur cluster biosynthetic enzyme
D0Z58_RS03470	COG1216	Glycosyl transferase, family 2
D0Z58_RS03530	COG1368	sulfuric ester hydrolase activity
D0Z58_RS03535	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0Z58_RS03555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0Z58_RS03560	COG0285	dihydrofolate synthase activity
D0Z58_RS03570	COG1104	cysteine desulfurase activity
D0Z58_RS03595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D0Z58_RS03605	COG0583	DNA-binding transcription factor activity
D0Z58_RS03615	COG0564	pseudouridine synthase activity
D0Z58_RS03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0Z58_RS03655	COG1136	(ABC) transporter
D0Z58_RS03660	COG0577	efflux transmembrane transporter activity
D0Z58_RS03665	COG0584	glycerophosphoryl diester phosphodiesterase
D0Z58_RS03675	COG1837	Belongs to the UPF0109 family
D0Z58_RS03725	COG1349	DNA-binding transcription factor activity
D0Z58_RS03730	COG1105	Belongs to the carbohydrate kinase PfkB family
D0Z58_RS03735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0Z58_RS03735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0Z58_RS03735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0Z58_RS03740	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0Z58_RS03740	COG1388	LysM domain
D0Z58_RS03745	COG1388	LysM domain
D0Z58_RS03745	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0Z58_RS03765	COG0105	UTP biosynthetic process
D0Z58_RS03785	COG0488	(ABC) transporter
D0Z58_RS03800	COG0242	peptide deformylase activity
D0Z58_RS03805	COG0737	Belongs to the 5'-nucleotidase family
D0Z58_RS03810	COG2357	RelA SpoT domain protein
D0Z58_RS03815	COG0745	RESPONSE REGULATOR receiver
D0Z58_RS03855	COG3425	synthase
D0Z58_RS03865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0Z58_RS03925	COG0583	DNA-binding transcription factor activity
D0Z58_RS03950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0Z58_RS03955	COG0765	amino acid transport
D0Z58_RS03975	COG0187	DNA topoisomerase II activity
D0Z58_RS03985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0Z58_RS04005	COG0539	negative regulation of cytoplasmic translation
D0Z58_RS04050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0Z58_RS04055	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D0Z58_RS04065	COG0300	oxidoreductase activity
D0Z58_RS04070	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D0Z58_RS04070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0Z58_RS04085	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0Z58_RS04090	COG2384	SAM-dependent methyltransferase
D0Z58_RS04100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0Z58_RS04105	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D0Z58_RS04115	COG1088	dTDP-glucose 4,6-dehydratase activity
D0Z58_RS04120	COG0582	viral genome integration into host DNA
D0Z58_RS04140	COG3561	AntA/AntB antirepressor
D0Z58_RS04415	COG1051	belongs to the nudix hydrolase family
D0Z58_RS04420	COG0628	permease
D0Z58_RS04425	COG0457	Tetratricopeptide repeat
D0Z58_RS04430	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D0Z58_RS04450	COG1129	ABC transporter
D0Z58_RS04470	COG0488	(ABC) transporter
D0Z58_RS04475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D0Z58_RS04480	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0Z58_RS04480	COG0022	dehydrogenase e1 component
D0Z58_RS04485	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0Z58_RS04505	COG5492	domain, Protein
D0Z58_RS04510	COG0095	Lipoate-protein ligase
D0Z58_RS04515	COG3442	glutamine amidotransferase
D0Z58_RS04520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0Z58_RS04525	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D0Z58_RS04545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0Z58_RS04555	COG0647	UMP catabolic process
D0Z58_RS04570	COG1518	maintenance of DNA repeat elements
D0Z58_RS04575	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
D0Z58_RS04590	COG0105	UTP biosynthetic process
D0Z58_RS04595	COG5433	transposase activity
D0Z58_RS04635	COG3715	PTS system
D0Z58_RS04640	COG3716	PTS system mannose fructose sorbose family IID component
D0Z58_RS04645	COG2972	Histidine kinase
D0Z58_RS04650	COG4753	response regulator
D0Z58_RS04650	COG2207	Transcriptional regulator
D0Z58_RS04660	COG1012	belongs to the aldehyde dehydrogenase family
D0Z58_RS04675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0Z58_RS04750	COG1131	(ABC) transporter
D0Z58_RS04765	COG1396	sequence-specific DNA binding
D0Z58_RS04795	COG0285	dihydrofolate synthase activity
D0Z58_RS04815	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0Z58_RS04830	COG1176	ABC-type spermidine putrescine transport system, permease component I
D0Z58_RS04835	COG1177	transmembrane transport
D0Z58_RS04845	COG4565	transcriptional regulatory protein
D0Z58_RS04850	COG3290	protein histidine kinase activity
D0Z58_RS04855	COG3493	citrate carrier protein
D0Z58_RS04870	COG3700	Belongs to the class B bacterial acid phosphatase family
D0Z58_RS04875	COG0038	chloride channel
D0Z58_RS04885	COG0628	permease
D0Z58_RS04895	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D0Z58_RS04910	COG1104	cysteine desulfurase activity
D0Z58_RS04925	COG2357	RelA SpoT domain protein
D0Z58_RS04935	COG0564	pseudouridine synthase activity
D0Z58_RS04940	COG0280	phosphate acetyltransferase
D0Z58_RS04945	COG4221	oxidoreductase activity
D0Z58_RS04960	COG1174	glycine betaine transport
D0Z58_RS04980	COG2233	PERMEase
D0Z58_RS05005	COG2890	protein-(glutamine-N5) methyltransferase activity
D0Z58_RS05035	COG1132	(ABC) transporter
D0Z58_RS05040	COG1132	(ABC) transporter
D0Z58_RS05060	COG3764	Sortase (surface protein transpeptidase)
D0Z58_RS05065	COG0346	lactoylglutathione lyase activity
D0Z58_RS05085	COG1272	protein, Hemolysin III
D0Z58_RS05105	COG0758	DNA mediated transformation
D0Z58_RS05110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0Z58_RS05155	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
D0Z58_RS05175	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0Z58_RS05185	COG2188	Transcriptional regulator
D0Z58_RS05205	COG0488	(ABC) transporter
D0Z58_RS05215	COG0351	phosphomethylpyrimidine kinase
D0Z58_RS05215	COG0352	thiamine-phosphate diphosphorylase activity
D0Z58_RS05220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0Z58_RS05225	COG1328	CTP reductase activity
D0Z58_RS05225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0Z58_RS05230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0Z58_RS05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D0Z58_RS05270	COG0095	Lipoate-protein ligase
D0Z58_RS05280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0Z58_RS05285	COG4684	Psort location CytoplasmicMembrane, score
D0Z58_RS05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0Z58_RS05295	COG1079	Belongs to the binding-protein-dependent transport system permease family
D0Z58_RS05300	COG4603	Belongs to the binding-protein-dependent transport system permease family
D0Z58_RS05305	COG3845	ABC transporter
D0Z58_RS05310	COG1744	ABC transporter substrate-binding protein PnrA-like
D0Z58_RS05315	COG0295	cytidine deaminase activity
D0Z58_RS05320	COG2813	Specifically methylates the guanine in position
D0Z58_RS05335	COG5002	protein histidine kinase activity
D0Z58_RS05340	COG0745	RESPONSE REGULATOR receiver
D0Z58_RS05355	COG0704	Plays a role in the regulation of phosphate uptake
D0Z58_RS05370	COG0581	inorganic phosphate transmembrane transporter activity
D0Z58_RS05375	COG0573	inorganic phosphate transmembrane transporter activity
D0Z58_RS05385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0Z58_RS05385	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
D0Z58_RS05390	COG0483	inositol monophosphate 1-phosphatase activity
D0Z58_RS05405	COG0196	riboflavin kinase activity
D0Z58_RS05435	COG1136	(ABC) transporter
D0Z58_RS05435	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0Z58_RS05485	COG1115	amino acid carrier protein
D0Z58_RS05490	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0Z58_RS05500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0Z58_RS05505	COG1126	abc transporter atp-binding protein
D0Z58_RS05510	COG0765	amino acid transport
D0Z58_RS05515	COG2824	Alkylphosphonate utilization operon protein PhnA
D0Z58_RS05530	COG0469	pyruvate kinase activity
D0Z58_RS05545	COG1725	Transcriptional regulator
D0Z58_RS05550	COG1131	(ABC) transporter
D0Z58_RS05575	COG0058	SHG alpha-glucan phosphorylase activity
D0Z58_RS05580	COG1640	4-alpha-glucanotransferase
D0Z58_RS05585	COG1609	Transcriptional regulator
D0Z58_RS05590	COG2182	Extracellular solute-binding protein
D0Z58_RS05595	COG1175	transmembrane transport
D0Z58_RS05600	COG3833	ABC-type maltose transport systems, permease component
D0Z58_RS05620	COG0657	acetylesterase activity
D0Z58_RS05625	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D0Z58_RS05635	COG1696	Membrane protein involved in D-alanine export
D0Z58_RS05655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0Z58_RS05660	COG1126	abc transporter atp-binding protein
D0Z58_RS05670	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0Z58_RS05680	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0Z58_RS05690	COG3711	transcriptional antiterminator
D0Z58_RS05690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0Z58_RS05700	COG2723	6-phospho-beta-galactosidase activity
D0Z58_RS05730	COG1187	pseudouridine synthase activity
D0Z58_RS05740	COG2814	Major facilitator Superfamily
D0Z58_RS05790	COG4109	DRTGG domain
D0Z58_RS05795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0Z58_RS05820	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D0Z58_RS05820	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D0Z58_RS05830	COG5433	transposase activity
D0Z58_RS05835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0Z58_RS05840	COG1956	GAF domain-containing protein
D0Z58_RS05860	COG0513	Belongs to the DEAD box helicase family
D0Z58_RS05865	COG0726	polysaccharide deacetylase
D0Z58_RS05885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0Z58_RS05890	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0Z58_RS05895	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0Z58_RS05920	COG1476	TRANSCRIPTIONal
D0Z58_RS05935	COG4122	O-methyltransferase activity
D0Z58_RS05940	COG2223	nitrite transmembrane transporter activity
D0Z58_RS05955	COG1187	pseudouridine synthase activity
D0Z58_RS06000	COG0658	competence protein
D0Z58_RS06000	COG2333	competence protein COMEC
D0Z58_RS06005	COG1555	photosystem II stabilization
D0Z58_RS06005	COG1596	polysaccharide export
D0Z58_RS06010	COG0204	Acyl-transferase
D0Z58_RS06015	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0Z58_RS06030	COG0513	Belongs to the DEAD box helicase family
D0Z58_RS06050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0Z58_RS06070	COG2116	formate transmembrane transporter activity
D0Z58_RS06080	COG1827	regulation of RNA biosynthetic process
D0Z58_RS06095	COG2217	Heavy metal translocating P-type atpase
D0Z58_RS06110	COG3177	Filamentation induced by cAMP protein fic
D0Z58_RS06335	COG1111	helicase
D0Z58_RS06335	COG1205	dead DEAH box helicase
D0Z58_RS06370	COG1396	sequence-specific DNA binding
D0Z58_RS06380	COG0582	viral genome integration into host DNA
D0Z58_RS06395	COG2755	lipolytic protein G-D-S-L family
D0Z58_RS06410	COG0497	DNA recombination
D0Z58_RS06415	COG1438	arginine binding
D0Z58_RS06420	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D0Z58_RS06445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0Z58_RS06450	COG0415	Belongs to the DNA photolyase family
D0Z58_RS06460	COG0765	amino acid transport
D0Z58_RS06465	COG4703	Protein of unknown function (DUF1797)
D0Z58_RS06470	COG0542	response to heat
D0Z58_RS06475	COG0494	nUDIX hydrolase
D0Z58_RS06490	COG3599	regulation of cell shape
D0Z58_RS06495	COG2302	S4 RNA-binding domain
D0Z58_RS06510	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0Z58_RS06545	COG1217	gtp-binding protein TYPA
D0Z58_RS06550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0Z58_RS06555	COG1940	carbohydrate kinase activity
D0Z58_RS06565	COG0783	Belongs to the Dps family
D0Z58_RS06580	COG4470	Protein conserved in bacteria
D0Z58_RS06585	COG1609	Transcriptional regulator
D0Z58_RS06590	COG3480	Lon protease (S16) C-terminal proteolytic domain
D0Z58_RS06600	COG0742	ribosomal rna small subunit methyltransferase
D0Z58_RS06610	COG0549	Belongs to the carbamate kinase family
D0Z58_RS06615	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0Z58_RS06620	COG1288	antiporter activity
D0Z58_RS06635	COG2235	arginine
D0Z58_RS06660	COG2972	Histidine kinase
D0Z58_RS06675	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0Z58_RS06680	COG0785	Cytochrome C biogenesis protein
D0Z58_RS06685	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
D0Z58_RS06690	COG1518	maintenance of DNA repeat elements
D0Z58_RS06755	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D0Z58_RS06755	COG1605	Chorismate mutase
D0Z58_RS06775	COG2226	methyltransferase
D0Z58_RS06785	COG3250	beta-galactosidase activity
D0Z58_RS06790	COG4753	response regulator
D0Z58_RS06790	COG2207	Transcriptional regulator
D0Z58_RS06795	COG2972	Histidine kinase
D0Z58_RS06805	COG1653	transport
D0Z58_RS06810	COG0395	ABC-type sugar transport system, permease component
D0Z58_RS06815	COG1175	transmembrane transport
D0Z58_RS06825	COG2723	6-phospho-beta-galactosidase activity
D0Z58_RS06830	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D0Z58_RS06845	COG0383	alpha-mannosidase activity
D0Z58_RS06955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D0Z58_RS06960	COG1739	Uncharacterized protein family UPF0029
D0Z58_RS06970	COG1098	S1 RNA binding domain
D0Z58_RS06980	COG2197	response regulator
D0Z58_RS06985	COG4585	Histidine kinase
D0Z58_RS06995	COG0515	serine threonine protein kinase
D0Z58_RS06995	COG2815	serine threonine protein kinase
D0Z58_RS07005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0Z58_RS07005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0Z58_RS07015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0Z58_RS07035	COG0583	DNA-binding transcription factor activity
D0Z58_RS07040	COG0183	Belongs to the thiolase family
D0Z58_RS07045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D0Z58_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
D0Z58_RS07075	COG0116	Belongs to the methyltransferase superfamily
D0Z58_RS07100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0Z58_RS07105	COG3579	cysteine-type endopeptidase activity
D0Z58_RS07115	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0Z58_RS07120	COG1113	amino acid transport
D0Z58_RS07125	COG0492	ferredoxin-NADP+ reductase activity
D0Z58_RS07135	COG1126	abc transporter atp-binding protein
D0Z58_RS07145	COG0513	Belongs to the DEAD box helicase family
D0Z58_RS07155	COG0768	penicillin binding
D0Z58_RS07190	COG1131	(ABC) transporter
D0Z58_RS07215	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0Z58_RS07220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0Z58_RS07260	COG1755	Isoprenylcysteine carboxyl methyltransferase
D0Z58_RS07265	COG0656	L-ascorbic acid biosynthetic process
D0Z58_RS07275	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0Z58_RS07295	COG0561	phosphatase activity
D0Z58_RS07300	COG2860	membrane
D0Z58_RS07360	COG2217	Heavy metal translocating P-type atpase
D0Z58_RS07390	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D0Z58_RS07395	COG0195	Participates in both transcription termination and antitermination
D0Z58_RS07415	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0Z58_RS07535	COG1783	phage Terminase large subunit
D0Z58_RS07655	COG4974	Belongs to the 'phage' integrase family
D0Z58_RS07675	COG4473	ABC transporter
D0Z58_RS07680	COG1131	(ABC) transporter
D0Z58_RS07685	COG0537	adenosine 5'-monophosphoramidase activity
D0Z58_RS07695	COG1316	TRANSCRIPTIONal
D0Z58_RS07705	COG0802	atpase or kinase
D0Z58_RS07710	COG2252	PERMEase
D0Z58_RS07715	COG0561	phosphatase activity
D0Z58_RS07725	COG3715	PTS system
D0Z58_RS07730	COG3716	PTS system mannose fructose sorbose family IID component
D0Z58_RS07755	COG0439	Biotin carboxylase
D0Z58_RS07770	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0Z58_RS07775	COG1028	Short-chain dehydrogenase reductase Sdr
D0Z58_RS07780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D0Z58_RS07805	COG1024	Enoyl-CoA hydratase
D0Z58_RS07810	COG0484	heat shock protein binding
D0Z58_RS07840	COG0588	phosphoglycerate mutase activity
D0Z58_RS07845	COG2261	transglycosylase associated protein
D0Z58_RS07880	COG1335	isochorismatase
D0Z58_RS07890	COG0436	Aminotransferase
D0Z58_RS07900	COG0561	phosphatase activity
D0Z58_RS07905	COG0252	asparaginase activity
D0Z58_RS07920	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0Z58_RS07930	COG1129	ABC transporter
D0Z58_RS07945	COG1132	(ABC) transporter
D0Z58_RS07950	COG4988	ABC transporter
D0Z58_RS07955	COG1120	ATPase activity
D0Z58_RS07980	COG3942	CHAP domain
D0Z58_RS07980	COG1388	LysM domain
D0Z58_RS08005	COG5433	transposase activity
D0Z58_RS08010	COG1482	cell wall glycoprotein biosynthetic process
D0Z58_RS08015	COG1940	carbohydrate kinase activity
D0Z58_RS08025	COG2190	(PTS) system
D0Z58_RS08025	COG1263	PTS System
D0Z58_RS08025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0Z58_RS08030	COG1621	beta-fructofuranosidase activity
D0Z58_RS08035	COG1609	Transcriptional regulator
D0Z58_RS08055	COG2131	deaminase
D0Z58_RS08060	COG0006	proline dipeptidase activity
D0Z58_RS08100	COG1194	a g-specific adenine glycosylase
D0Z58_RS08110	COG3118	belongs to the thioredoxin family
D0Z58_RS08140	COG0681	Belongs to the peptidase S26 family
D0Z58_RS08145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0Z58_RS08160	COG1882	Formate acetyltransferase
D0Z58_RS08165	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D0Z58_RS08180	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0Z58_RS08190	COG2814	Major facilitator Superfamily
D0Z58_RS08195	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0Z58_RS08220	COG0789	Transcriptional regulator
D0Z58_RS08235	COG2081	HI0933 family
D0Z58_RS08245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0Z58_RS08250	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D0Z58_RS08270	COG0456	acetyltransferase
D0Z58_RS08275	COG1214	PFAM Peptidase M22, glycoprotease
D0Z58_RS08290	COG0174	glutamine synthetase
D0Z58_RS08295	COG0789	Transcriptional regulator
D0Z58_RS08310	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
D0Z58_RS08365	COG0668	transmembrane transport
D0Z58_RS08375	COG4720	Psort location CytoplasmicMembrane, score
D0Z58_RS08380	COG0351	phosphomethylpyrimidine kinase
D0Z58_RS08425	COG1929	Belongs to the glycerate kinase type-1 family
D0Z58_RS08430	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D0Z58_RS08460	COG0577	efflux transmembrane transporter activity
D0Z58_RS08465	COG1136	(ABC) transporter
D0Z58_RS08490	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0Z58_RS08490	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0Z58_RS08495	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0Z58_RS08545	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0Z58_RS08550	COG1476	TRANSCRIPTIONal
D0Z58_RS08570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0Z58_RS08580	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D0Z58_RS08600	COG1045	serine acetyltransferase
D0Z58_RS08615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0Z58_RS08630	COG3711	transcriptional antiterminator
D0Z58_RS08660	COG1846	Transcriptional regulator
D0Z58_RS08680	COG4589	Belongs to the CDS family
D0Z58_RS08690	COG1862	Preprotein translocase
D0Z58_RS08700	COG1523	belongs to the glycosyl hydrolase 13 family
D0Z58_RS08715	COG3842	ATPase activity
D0Z58_RS08755	COG2190	(PTS) system
D0Z58_RS08755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0Z58_RS08755	COG1263	PTS System
D0Z58_RS08760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0Z58_RS08805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0Z58_RS08810	COG0512	Glutamine amidotransferase of anthranilate synthase
D0Z58_RS08815	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0Z58_RS08855	COG0601	transmembrane transport
D0Z58_RS08885	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0Z58_RS08890	COG5433	transposase activity
D0Z58_RS08895	COG1404	Belongs to the peptidase S8 family
D0Z58_RS08895	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0Z58_RS08910	COG1196	nuclear chromosome segregation
D0Z58_RS08915	COG3711	transcriptional antiterminator
D0Z58_RS08930	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0Z58_RS08930	COG3942	CHAP domain
D0Z58_RS08935	COG2205	protein histidine kinase activity
D0Z58_RS08940	COG0745	RESPONSE REGULATOR receiver
D0Z58_RS08945	COG0577	efflux transmembrane transporter activity
D0Z58_RS08950	COG1136	(ABC) transporter
D0Z58_RS09030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0Z58_RS09045	COG1882	Formate acetyltransferase
D0Z58_RS09050	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0Z58_RS09055	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0Z58_RS09060	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0Z58_RS09065	COG2390	Transcriptional regulator
D0Z58_RS09070	COG1349	DNA-binding transcription factor activity
D0Z58_RS09075	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0Z58_RS09095	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0Z58_RS09110	COG0564	pseudouridine synthase activity
D0Z58_RS09145	COG0542	response to heat
D0Z58_RS09150	COG4463	regulation of RNA biosynthetic process
D0Z58_RS09165	COG0450	alkyl hydroperoxide reductase
D0Z58_RS09180	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0Z58_RS09190	COG3404	Formiminotransferase-cyclodeaminase
D0Z58_RS09205	COG0531	amino acid
D0Z58_RS09235	COG3590	peptidase
D0Z58_RS09240	COG0366	Alpha amylase catalytic
D0Z58_RS09245	COG1263	PTS System
D0Z58_RS09245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0Z58_RS09250	COG2188	Transcriptional regulator
D0Z58_RS09260	COG1733	regulation of RNA biosynthetic process
D0Z58_RS09265	COG2514	catechol 2,3-dioxygenase activity
D0Z58_RS09275	COG0602	queuosine metabolic process
D0Z58_RS09285	COG0673	inositol 2-dehydrogenase activity
D0Z58_RS09290	COG1328	CTP reductase activity
D0Z58_RS09315	COG1393	Belongs to the ArsC family
D0Z58_RS09330	COG0519	Catalyzes the synthesis of GMP from XMP
D0Z58_RS09340	COG2814	Major facilitator Superfamily
D0Z58_RS09375	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0Z58_RS09380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0Z58_RS09385	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0Z58_RS09405	COG0267	Belongs to the bacterial ribosomal protein bL33 family
D0Z58_RS09470	COG1511	domain protein
D0Z58_RS09490	COG0305	Participates in initiation and elongation during chromosome replication
D0Z58_RS09520	COG1760	l-serine dehydratase
D0Z58_RS09525	COG1760	l-serine dehydratase
D0Z58_RS09530	COG0741	lytic transglycosylase activity
D0Z58_RS09535	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D0Z58_RS09550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0Z58_RS09560	COG0612	Peptidase, M16
D0Z58_RS09580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D0Z58_RS09600	COG0517	IMP dehydrogenase activity
D0Z58_RS09600	COG0516	GMP reductase activity
D0Z58_RS09610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0Z58_RS09615	COG0488	(ABC) transporter
D0Z58_RS09655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0Z58_RS09660	COG1475	DNA binding