locus-tag	class	description
EZY40_RS00010	COG0592	DNA-directed DNA polymerase activity
EZY40_RS00020	COG0012	GTP binding
EZY40_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EZY40_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EZY40_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EZY40_RS00065	COG0531	amino acid
EZY40_RS00180	COG3942	CHAP domain
EZY40_RS00200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EZY40_RS00210	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EZY40_RS00225	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EZY40_RS00245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EZY40_RS00260	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EZY40_RS00275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EZY40_RS00290	COG1454	alcohol dehydrogenase
EZY40_RS00290	COG1012	belongs to the aldehyde dehydrogenase family
EZY40_RS00295	COG1064	alcohol dehydrogenase
EZY40_RS00300	COG0534	Mate efflux family protein
EZY40_RS00410	COG0201	protein transport
EZY40_RS00550	COG1121	(ABC) transporter
EZY40_RS00555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EZY40_RS00570	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EZY40_RS00590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EZY40_RS00595	COG1459	type II secretion system
EZY40_RS00600	COG4537	Required for transformation and DNA binding
EZY40_RS00640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EZY40_RS00645	COG1363	Peptidase, m42
EZY40_RS00660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EZY40_RS00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EZY40_RS00675	COG1428	Deoxynucleoside kinase
EZY40_RS00680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EZY40_RS00720	COG4509	Sortase family
EZY40_RS00745	COG2031	fatty acid transporter
EZY40_RS00760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EZY40_RS00775	COG0251	oxidation-reduction process
EZY40_RS00790	COG1269	ATP hydrolysis coupled proton transport
EZY40_RS00795	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EZY40_RS00805	COG1527	subunit (C
EZY40_RS00810	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EZY40_RS00845	COG1744	ABC transporter substrate-binding protein PnrA-like
EZY40_RS00885	COG0626	cystathionine gamma-synthase activity
EZY40_RS00915	COG3623	hexulose-6-phosphate isomerase
EZY40_RS00940	COG3448	diguanylate cyclase activity
EZY40_RS00940	COG4175	Glycine betaine
EZY40_RS00950	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EZY40_RS00950	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EZY40_RS00970	COG3969	phosphoadenosine phosphosulfate
EZY40_RS00975	COG1475	DNA binding
EZY40_RS01000	COG0157	Belongs to the NadC ModD family
EZY40_RS01030	COG1268	BioY protein
EZY40_RS01035	COG1234	tRNA 3'-trailer cleavage
EZY40_RS01070	COG0705	Rhomboid family
EZY40_RS01070	COG0457	Tetratricopeptide repeat
EZY40_RS01090	COG1132	(ABC) transporter
EZY40_RS01095	COG1132	(ABC) transporter
EZY40_RS01105	COG0756	dUTP diphosphatase activity
EZY40_RS01130	COG3290	protein histidine kinase activity
EZY40_RS01155	COG1847	R3H domain protein
EZY40_RS01175	COG1175	transmembrane transport
EZY40_RS01180	COG0395	ABC-type sugar transport system, permease component
EZY40_RS01195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EZY40_RS01210	COG0084	hydrolase, TatD family'
EZY40_RS01235	COG1564	THIamine pyrophosphokinase
EZY40_RS01250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EZY40_RS01275	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EZY40_RS01290	COG0765	amino acid transport
EZY40_RS01310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EZY40_RS01320	COG0719	Fe-S assembly protein
EZY40_RS01325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EZY40_RS01340	COG1686	Belongs to the peptidase S11 family
EZY40_RS01345	COG1686	Belongs to the peptidase S11 family
EZY40_RS01350	COG4166	transmembrane transport
EZY40_RS01355	COG0601	transmembrane transport
EZY40_RS01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EZY40_RS01365	COG0444	Belongs to the ABC transporter superfamily
EZY40_RS01415	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EZY40_RS01420	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EZY40_RS01425	COG1534	Rna-binding protein
EZY40_RS01435	COG1713	HD superfamily hydrolase involved in NAD metabolism
EZY40_RS01440	COG0799	negative regulation of ribosome biogenesis
EZY40_RS01445	COG2226	methyltransferase
EZY40_RS01465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EZY40_RS01470	COG1464	Belongs to the NlpA lipoprotein family
EZY40_RS01485	COG1114	Component of the transport system for branched-chain amino acids
EZY40_RS01495	COG0569	domain protein
EZY40_RS01500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EZY40_RS01510	COG1704	LemA family
EZY40_RS01525	COG0745	RESPONSE REGULATOR receiver
EZY40_RS01545	COG1484	DNA-dependent DNA replication
EZY40_RS01555	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EZY40_RS01575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EZY40_RS01590	COG1254	Belongs to the acylphosphatase family
EZY40_RS01595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EZY40_RS01650	COG1187	pseudouridine synthase activity
EZY40_RS01665	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EZY40_RS01670	COG0671	phosphoesterase, PA-phosphatase related
EZY40_RS01675	COG1242	4 iron, 4 sulfur cluster binding
EZY40_RS01680	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EZY40_RS01685	COG1253	flavin adenine dinucleotide binding
EZY40_RS01690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EZY40_RS01705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EZY40_RS01710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EZY40_RS01715	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EZY40_RS01720	COG1120	ATPase activity
EZY40_RS01730	COG2244	polysaccharide biosynthetic process
EZY40_RS01760	COG0470	DNA polymerase III
EZY40_RS01790	COG1393	Belongs to the ArsC family
EZY40_RS01795	COG0708	Exodeoxyribonuclease III
EZY40_RS01800	COG1304	FMN binding
EZY40_RS01920	COG1028	Short-chain dehydrogenase reductase Sdr
EZY40_RS01925	COG0673	inositol 2-dehydrogenase activity
EZY40_RS01940	COG0494	nUDIX hydrolase
EZY40_RS01950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EZY40_RS01995	COG5433	transposase activity
EZY40_RS02050	COG1702	phosphate starvation-inducible protein PhoH
EZY40_RS02055	COG1573	uracil-dna glycosylase
EZY40_RS02065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EZY40_RS02155	COG0433	COG0433 Predicted ATPase
EZY40_RS02160	COG2814	Major facilitator Superfamily
EZY40_RS02175	COG0557	exoribonuclease II activity
EZY40_RS02205	COG0463	Glycosyl transferase, family 2
EZY40_RS02215	COG0778	Nitroreductase
EZY40_RS02220	COG0006	proline dipeptidase activity
EZY40_RS02225	COG1609	Transcriptional regulator
EZY40_RS02235	COG0438	transferase activity, transferring glycosyl groups
EZY40_RS02245	COG4555	ABC transporter
EZY40_RS02265	COG0183	Belongs to the thiolase family
EZY40_RS02280	COG0745	RESPONSE REGULATOR receiver
EZY40_RS02285	COG5002	protein histidine kinase activity
EZY40_RS02290	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EZY40_RS02300	COG1196	nuclear chromosome segregation
EZY40_RS02315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EZY40_RS02400	COG4695	Portal protein
EZY40_RS02410	COG0561	phosphatase activity
EZY40_RS02415	COG0561	phosphatase activity
EZY40_RS02420	COG0552	protein localization to endoplasmic reticulum
EZY40_RS02425	COG0477	Major facilitator Superfamily
EZY40_RS02430	COG3711	transcriptional antiterminator
EZY40_RS02435	COG1263	PTS System
EZY40_RS02435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EZY40_RS02435	COG2190	(PTS) system
EZY40_RS02445	COG3689	TIGRFAM TIGR03943 family protein
EZY40_RS02450	COG0701	Predicted permease
EZY40_RS02460	COG2183	response to ionizing radiation
EZY40_RS02505	COG0826	peptidase U32
EZY40_RS02510	COG4443	Transcriptional Coactivator p15 (PC4)
EZY40_RS02555	COG0386	Belongs to the glutathione peroxidase family
EZY40_RS02560	COG1164	Oligoendopeptidase f
EZY40_RS02570	COG0772	Belongs to the SEDS family
EZY40_RS02605	COG1078	dGTPase activity
EZY40_RS02620	COG1609	Transcriptional regulator
EZY40_RS02630	COG3716	PTS system mannose fructose sorbose family IID component
EZY40_RS02635	COG3715	PTS system
EZY40_RS02640	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EZY40_RS02655	COG1028	Short-chain dehydrogenase reductase Sdr
EZY40_RS02685	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EZY40_RS02695	COG2884	Cell division ATP-binding protein ftsE
EZY40_RS02700	COG2177	Part of the ABC transporter FtsEX involved in
EZY40_RS02715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EZY40_RS02715	COG1199	ATP-dependent helicase activity
EZY40_RS02720	COG0436	Aminotransferase
EZY40_RS02860	COG1475	DNA binding
EZY40_RS02895	COG1705	Flagellar rod assembly protein muramidase FlgJ
EZY40_RS02920	COG2188	Transcriptional regulator
EZY40_RS02925	COG2222	sugar isomerase
EZY40_RS02935	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EZY40_RS02940	COG0716	FMN binding
EZY40_RS02950	COG0038	chloride channel
EZY40_RS03025	COG1131	(ABC) transporter
EZY40_RS03045	COG4708	membrane
EZY40_RS03055	COG1597	lipid kinase activity
EZY40_RS03140	COG0577	efflux transmembrane transporter activity
EZY40_RS03145	COG1136	(ABC) transporter
EZY40_RS03150	COG2321	neutral zinc metallopeptidase
EZY40_RS03165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EZY40_RS03175	COG1970	mechanosensitive ion channel activity
EZY40_RS03180	COG0358	DNA primase activity
EZY40_RS03185	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EZY40_RS03190	COG2151	metal-sulfur cluster biosynthetic enzyme
EZY40_RS03235	COG1216	Glycosyl transferase, family 2
EZY40_RS03295	COG1368	sulfuric ester hydrolase activity
EZY40_RS03300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EZY40_RS03320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EZY40_RS03325	COG0285	dihydrofolate synthase activity
EZY40_RS03335	COG1104	cysteine desulfurase activity
EZY40_RS03360	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EZY40_RS03365	COG0583	DNA-binding transcription factor activity
EZY40_RS03375	COG0564	pseudouridine synthase activity
EZY40_RS03405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EZY40_RS03410	COG1136	(ABC) transporter
EZY40_RS03415	COG0577	efflux transmembrane transporter activity
EZY40_RS03420	COG0584	glycerophosphoryl diester phosphodiesterase
EZY40_RS03430	COG1837	Belongs to the UPF0109 family
EZY40_RS03480	COG1349	DNA-binding transcription factor activity
EZY40_RS03485	COG1105	Belongs to the carbohydrate kinase PfkB family
EZY40_RS03490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EZY40_RS03490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EZY40_RS03490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EZY40_RS03495	COG1388	LysM domain
EZY40_RS03495	COG1705	Flagellar rod assembly protein muramidase FlgJ
EZY40_RS03500	COG1388	LysM domain
EZY40_RS03500	COG1705	Flagellar rod assembly protein muramidase FlgJ
EZY40_RS03520	COG0105	UTP biosynthetic process
EZY40_RS03540	COG0488	(ABC) transporter
EZY40_RS03555	COG0242	peptide deformylase activity
EZY40_RS03565	COG2357	RelA SpoT domain protein
EZY40_RS03570	COG0745	RESPONSE REGULATOR receiver
EZY40_RS03605	COG3425	synthase
EZY40_RS03615	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EZY40_RS03675	COG0583	DNA-binding transcription factor activity
EZY40_RS03700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EZY40_RS03705	COG0765	amino acid transport
EZY40_RS03725	COG0187	DNA topoisomerase II activity
EZY40_RS03735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EZY40_RS03755	COG0539	negative regulation of cytoplasmic translation
EZY40_RS03800	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EZY40_RS03805	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EZY40_RS03815	COG0300	oxidoreductase activity
EZY40_RS03820	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EZY40_RS03820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EZY40_RS03835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EZY40_RS03840	COG2384	SAM-dependent methyltransferase
EZY40_RS03850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EZY40_RS03855	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EZY40_RS03865	COG1088	dTDP-glucose 4,6-dehydratase activity
EZY40_RS03870	COG1051	belongs to the nudix hydrolase family
EZY40_RS03875	COG0628	permease
EZY40_RS03880	COG0457	Tetratricopeptide repeat
EZY40_RS03885	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EZY40_RS03905	COG1129	ABC transporter
EZY40_RS03925	COG0488	(ABC) transporter
EZY40_RS03930	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EZY40_RS03935	COG0022	dehydrogenase e1 component
EZY40_RS03935	COG0508	dehydrogenase complex catalyzes the overall conversion of
EZY40_RS03940	COG0508	dehydrogenase complex catalyzes the overall conversion of
EZY40_RS03955	COG5492	domain, Protein
EZY40_RS03960	COG0095	Lipoate-protein ligase
EZY40_RS03965	COG3442	glutamine amidotransferase
EZY40_RS03970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EZY40_RS03975	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EZY40_RS03995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EZY40_RS04005	COG0647	UMP catabolic process
EZY40_RS04020	COG1518	maintenance of DNA repeat elements
EZY40_RS04025	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EZY40_RS04070	COG3715	PTS system
EZY40_RS04075	COG3716	PTS system mannose fructose sorbose family IID component
EZY40_RS04080	COG2972	Histidine kinase
EZY40_RS04085	COG2207	Transcriptional regulator
EZY40_RS04085	COG4753	response regulator
EZY40_RS04095	COG1012	belongs to the aldehyde dehydrogenase family
EZY40_RS04110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EZY40_RS04190	COG1131	(ABC) transporter
EZY40_RS04235	COG0285	dihydrofolate synthase activity
EZY40_RS04255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EZY40_RS04270	COG1176	ABC-type spermidine putrescine transport system, permease component I
EZY40_RS04275	COG1177	transmembrane transport
EZY40_RS04285	COG4565	transcriptional regulatory protein
EZY40_RS04290	COG3290	protein histidine kinase activity
EZY40_RS04305	COG3700	Belongs to the class B bacterial acid phosphatase family
EZY40_RS04310	COG0038	chloride channel
EZY40_RS04320	COG0628	permease
EZY40_RS04330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EZY40_RS04345	COG1104	cysteine desulfurase activity
EZY40_RS04360	COG2357	RelA SpoT domain protein
EZY40_RS04370	COG0564	pseudouridine synthase activity
EZY40_RS04375	COG0280	phosphate acetyltransferase
EZY40_RS04380	COG4221	oxidoreductase activity
EZY40_RS04395	COG1174	glycine betaine transport
EZY40_RS04410	COG2233	PERMEase
EZY40_RS04435	COG2890	protein-(glutamine-N5) methyltransferase activity
EZY40_RS04465	COG1132	(ABC) transporter
EZY40_RS04470	COG1132	(ABC) transporter
EZY40_RS04490	COG3764	Sortase (surface protein transpeptidase)
EZY40_RS04495	COG0346	lactoylglutathione lyase activity
EZY40_RS04515	COG1272	protein, Hemolysin III
EZY40_RS04535	COG0758	DNA mediated transformation
EZY40_RS04540	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EZY40_RS04590	COG0511	ligase activity, forming carbon-carbon bonds
EZY40_RS04595	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EZY40_RS04610	COG2851	Citrate transporter
EZY40_RS04620	COG0511	ligase activity, forming carbon-carbon bonds
EZY40_RS04625	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EZY40_RS04655	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EZY40_RS04675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EZY40_RS04685	COG2188	Transcriptional regulator
EZY40_RS04705	COG0488	(ABC) transporter
EZY40_RS04715	COG0352	thiamine-phosphate diphosphorylase activity
EZY40_RS04715	COG0351	phosphomethylpyrimidine kinase
EZY40_RS04720	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EZY40_RS04725	COG1328	CTP reductase activity
EZY40_RS04725	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EZY40_RS04730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EZY40_RS04760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EZY40_RS04780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EZY40_RS04785	COG4684	Psort location CytoplasmicMembrane, score
EZY40_RS04790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EZY40_RS04795	COG1079	Belongs to the binding-protein-dependent transport system permease family
EZY40_RS04800	COG4603	Belongs to the binding-protein-dependent transport system permease family
EZY40_RS04805	COG3845	ABC transporter
EZY40_RS04810	COG1744	ABC transporter substrate-binding protein PnrA-like
EZY40_RS04815	COG0295	cytidine deaminase activity
EZY40_RS04820	COG2813	Specifically methylates the guanine in position
EZY40_RS04835	COG5002	protein histidine kinase activity
EZY40_RS04840	COG0745	RESPONSE REGULATOR receiver
EZY40_RS04850	COG0704	Plays a role in the regulation of phosphate uptake
EZY40_RS04865	COG0581	inorganic phosphate transmembrane transporter activity
EZY40_RS04870	COG0573	inorganic phosphate transmembrane transporter activity
EZY40_RS04880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EZY40_RS04880	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EZY40_RS04885	COG0483	inositol monophosphate 1-phosphatase activity
EZY40_RS04900	COG0196	riboflavin kinase activity
EZY40_RS04930	COG1136	(ABC) transporter
EZY40_RS04930	COG4591	ABC-type transport system involved in lipoprotein release permease component
EZY40_RS04980	COG1115	amino acid carrier protein
EZY40_RS04985	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EZY40_RS04995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EZY40_RS05000	COG1126	abc transporter atp-binding protein
EZY40_RS05005	COG0765	amino acid transport
EZY40_RS05010	COG2824	Alkylphosphonate utilization operon protein PhnA
EZY40_RS05025	COG0469	pyruvate kinase activity
EZY40_RS05040	COG1725	Transcriptional regulator
EZY40_RS05045	COG1131	(ABC) transporter
EZY40_RS05070	COG0058	SHG alpha-glucan phosphorylase activity
EZY40_RS05075	COG1640	4-alpha-glucanotransferase
EZY40_RS05080	COG1609	Transcriptional regulator
EZY40_RS05085	COG2182	Extracellular solute-binding protein
EZY40_RS05090	COG1175	transmembrane transport
EZY40_RS05095	COG3833	ABC-type maltose transport systems, permease component
EZY40_RS05110	COG3833	ABC-type maltose transport systems, permease component
EZY40_RS05115	COG1175	transmembrane transport
EZY40_RS05125	COG0366	Alpha amylase catalytic
EZY40_RS05130	COG2182	Extracellular solute-binding protein
EZY40_RS05135	COG0657	acetylesterase activity
EZY40_RS05140	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EZY40_RS05150	COG1696	Membrane protein involved in D-alanine export
EZY40_RS05170	COG0765	amino acid transport
EZY40_RS05175	COG1126	abc transporter atp-binding protein
EZY40_RS05180	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EZY40_RS05190	COG1447	Phosphotransferase system cellobiose-specific component IIA
EZY40_RS05200	COG3711	transcriptional antiterminator
EZY40_RS05200	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EZY40_RS05210	COG2723	6-phospho-beta-galactosidase activity
EZY40_RS05240	COG1187	pseudouridine synthase activity
EZY40_RS05250	COG2814	Major facilitator Superfamily
EZY40_RS05300	COG4109	DRTGG domain
EZY40_RS05305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EZY40_RS05330	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EZY40_RS05330	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EZY40_RS05340	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EZY40_RS05345	COG1956	GAF domain-containing protein
EZY40_RS05365	COG0513	Belongs to the DEAD box helicase family
EZY40_RS05370	COG0726	polysaccharide deacetylase
EZY40_RS05390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EZY40_RS05395	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EZY40_RS05400	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EZY40_RS05425	COG1476	TRANSCRIPTIONal
EZY40_RS05440	COG4122	O-methyltransferase activity
EZY40_RS05445	COG2223	nitrite transmembrane transporter activity
EZY40_RS05460	COG1187	pseudouridine synthase activity
EZY40_RS05505	COG2333	competence protein COMEC
EZY40_RS05505	COG0658	competence protein
EZY40_RS05510	COG1596	polysaccharide export
EZY40_RS05510	COG1555	photosystem II stabilization
EZY40_RS05515	COG0204	Acyl-transferase
EZY40_RS05520	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EZY40_RS05535	COG0513	Belongs to the DEAD box helicase family
EZY40_RS05550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EZY40_RS05565	COG0768	penicillin binding
EZY40_RS05570	COG2116	formate transmembrane transporter activity
EZY40_RS05580	COG1827	regulation of RNA biosynthetic process
EZY40_RS05595	COG2217	Heavy metal translocating P-type atpase
EZY40_RS05610	COG2755	lipolytic protein G-D-S-L family
EZY40_RS05625	COG0497	DNA recombination
EZY40_RS05630	COG1438	arginine binding
EZY40_RS05635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EZY40_RS05660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EZY40_RS05665	COG0415	Belongs to the DNA photolyase family
EZY40_RS05675	COG0765	amino acid transport
EZY40_RS05680	COG4703	Protein of unknown function (DUF1797)
EZY40_RS05685	COG0542	response to heat
EZY40_RS05690	COG0494	nUDIX hydrolase
EZY40_RS05705	COG3599	regulation of cell shape
EZY40_RS05710	COG2302	S4 RNA-binding domain
EZY40_RS05760	COG1217	gtp-binding protein TYPA
EZY40_RS05765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EZY40_RS05770	COG1940	carbohydrate kinase activity
EZY40_RS05780	COG0783	Belongs to the Dps family
EZY40_RS05795	COG4470	Protein conserved in bacteria
EZY40_RS05800	COG1609	Transcriptional regulator
EZY40_RS05805	COG3480	Lon protease (S16) C-terminal proteolytic domain
EZY40_RS05815	COG0742	ribosomal rna small subunit methyltransferase
EZY40_RS05825	COG0549	Belongs to the carbamate kinase family
EZY40_RS05830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EZY40_RS05835	COG1288	antiporter activity
EZY40_RS05850	COG2235	arginine
EZY40_RS05875	COG2972	Histidine kinase
EZY40_RS05890	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EZY40_RS05895	COG0785	Cytochrome C biogenesis protein
EZY40_RS05900	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EZY40_RS05905	COG1518	maintenance of DNA repeat elements
EZY40_RS05960	COG5433	transposase activity
EZY40_RS05970	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EZY40_RS05970	COG1605	Chorismate mutase
EZY40_RS05990	COG2226	methyltransferase
EZY40_RS06000	COG3250	beta-galactosidase activity
EZY40_RS06005	COG2207	Transcriptional regulator
EZY40_RS06005	COG4753	response regulator
EZY40_RS06010	COG2972	Histidine kinase
EZY40_RS06020	COG1653	transport
EZY40_RS06025	COG0395	ABC-type sugar transport system, permease component
EZY40_RS06030	COG1175	transmembrane transport
EZY40_RS06035	COG1940	carbohydrate kinase activity
EZY40_RS06040	COG2723	6-phospho-beta-galactosidase activity
EZY40_RS06045	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EZY40_RS06060	COG0383	alpha-mannosidase activity
EZY40_RS06155	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EZY40_RS06160	COG1739	Uncharacterized protein family UPF0029
EZY40_RS06170	COG1098	S1 RNA binding domain
EZY40_RS06180	COG2197	response regulator
EZY40_RS06185	COG4585	Histidine kinase
EZY40_RS06195	COG0515	serine threonine protein kinase
EZY40_RS06195	COG2815	serine threonine protein kinase
EZY40_RS06205	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EZY40_RS06205	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EZY40_RS06215	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EZY40_RS06235	COG0583	DNA-binding transcription factor activity
EZY40_RS06240	COG0183	Belongs to the thiolase family
EZY40_RS06255	COG1028	Short-chain dehydrogenase reductase Sdr
EZY40_RS06260	COG2610	gluconate transmembrane transporter activity
EZY40_RS06275	COG0116	Belongs to the methyltransferase superfamily
EZY40_RS06300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EZY40_RS06305	COG3579	cysteine-type endopeptidase activity
EZY40_RS06315	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EZY40_RS06320	COG1113	amino acid transport
EZY40_RS06325	COG0492	ferredoxin-NADP+ reductase activity
EZY40_RS06335	COG1126	abc transporter atp-binding protein
EZY40_RS06345	COG0513	Belongs to the DEAD box helicase family
EZY40_RS06355	COG0768	penicillin binding
EZY40_RS06390	COG1131	(ABC) transporter
EZY40_RS06415	COG0446	pyridine nucleotide-disulphide oxidoreductase
EZY40_RS06420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EZY40_RS06455	COG1755	Isoprenylcysteine carboxyl methyltransferase
EZY40_RS06460	COG0656	L-ascorbic acid biosynthetic process
EZY40_RS06470	COG1283	sodium-dependent phosphate transmembrane transporter activity
EZY40_RS06490	COG0561	phosphatase activity
EZY40_RS06495	COG2860	membrane
EZY40_RS06550	COG2217	Heavy metal translocating P-type atpase
EZY40_RS06580	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EZY40_RS06585	COG0195	Participates in both transcription termination and antitermination
EZY40_RS06610	COG4473	ABC transporter
EZY40_RS06615	COG1131	(ABC) transporter
EZY40_RS06620	COG0537	adenosine 5'-monophosphoramidase activity
EZY40_RS06630	COG1316	TRANSCRIPTIONal
EZY40_RS06640	COG0802	atpase or kinase
EZY40_RS06645	COG2252	PERMEase
EZY40_RS06650	COG0561	phosphatase activity
EZY40_RS06660	COG3715	PTS system
EZY40_RS06665	COG3716	PTS system mannose fructose sorbose family IID component
EZY40_RS06690	COG0439	Biotin carboxylase
EZY40_RS06705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EZY40_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
EZY40_RS06715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EZY40_RS06740	COG1024	Enoyl-CoA hydratase
EZY40_RS06775	COG0588	phosphoglycerate mutase activity
EZY40_RS06780	COG2261	transglycosylase associated protein
EZY40_RS06810	COG1335	isochorismatase
EZY40_RS06820	COG0436	Aminotransferase
EZY40_RS06830	COG0561	phosphatase activity
EZY40_RS06835	COG0252	asparaginase activity
EZY40_RS06850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EZY40_RS06855	COG1129	ABC transporter
EZY40_RS06870	COG1132	(ABC) transporter
EZY40_RS06875	COG4988	ABC transporter
EZY40_RS06905	COG3942	CHAP domain
EZY40_RS06905	COG1388	LysM domain
EZY40_RS06935	COG1482	cell wall glycoprotein biosynthetic process
EZY40_RS06940	COG1940	carbohydrate kinase activity
EZY40_RS06950	COG2190	(PTS) system
EZY40_RS06950	COG1263	PTS System
EZY40_RS06950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EZY40_RS06955	COG1621	beta-fructofuranosidase activity
EZY40_RS06960	COG1609	Transcriptional regulator
EZY40_RS06980	COG2131	deaminase
EZY40_RS06985	COG0006	proline dipeptidase activity
EZY40_RS07025	COG1194	a g-specific adenine glycosylase
EZY40_RS07035	COG3118	belongs to the thioredoxin family
EZY40_RS07065	COG0681	Belongs to the peptidase S26 family
EZY40_RS07070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EZY40_RS07085	COG1882	Formate acetyltransferase
EZY40_RS07090	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EZY40_RS07105	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EZY40_RS07110	COG2814	Major facilitator Superfamily
EZY40_RS07115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EZY40_RS07140	COG0789	Transcriptional regulator
EZY40_RS07155	COG2081	HI0933 family
EZY40_RS07165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EZY40_RS07170	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EZY40_RS07190	COG0456	acetyltransferase
EZY40_RS07195	COG1214	PFAM Peptidase M22, glycoprotease
EZY40_RS07210	COG0174	glutamine synthetase
EZY40_RS07215	COG0789	Transcriptional regulator
EZY40_RS07230	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EZY40_RS07285	COG0668	transmembrane transport
EZY40_RS07295	COG4720	Psort location CytoplasmicMembrane, score
EZY40_RS07300	COG0351	phosphomethylpyrimidine kinase
EZY40_RS07350	COG5433	transposase activity
EZY40_RS07355	COG1929	Belongs to the glycerate kinase type-1 family
EZY40_RS07360	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EZY40_RS07390	COG0577	efflux transmembrane transporter activity
EZY40_RS07395	COG1136	(ABC) transporter
EZY40_RS07415	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EZY40_RS07415	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EZY40_RS07420	COG1447	Phosphotransferase system cellobiose-specific component IIA
EZY40_RS07475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EZY40_RS07480	COG1476	TRANSCRIPTIONal
EZY40_RS07500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EZY40_RS07510	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EZY40_RS07530	COG1045	serine acetyltransferase
EZY40_RS07545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EZY40_RS07590	COG1846	Transcriptional regulator
EZY40_RS07610	COG4589	Belongs to the CDS family
EZY40_RS07620	COG1862	Preprotein translocase
EZY40_RS07630	COG1523	belongs to the glycosyl hydrolase 13 family
EZY40_RS07640	COG3842	ATPase activity
EZY40_RS07680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EZY40_RS07680	COG2190	(PTS) system
EZY40_RS07680	COG1263	PTS System
EZY40_RS07685	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EZY40_RS07700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EZY40_RS07705	COG0512	Glutamine amidotransferase of anthranilate synthase
EZY40_RS07710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EZY40_RS07750	COG0601	transmembrane transport
EZY40_RS07760	COG1122	ATPase activity
EZY40_RS07780	COG0803	Belongs to the bacterial solute-binding protein 9 family
EZY40_RS07810	COG3711	transcriptional antiterminator
EZY40_RS07820	COG1705	Flagellar rod assembly protein muramidase FlgJ
EZY40_RS07820	COG3942	CHAP domain
EZY40_RS07825	COG2205	protein histidine kinase activity
EZY40_RS07830	COG0745	RESPONSE REGULATOR receiver
EZY40_RS07835	COG0577	efflux transmembrane transporter activity
EZY40_RS07840	COG1136	(ABC) transporter
EZY40_RS07915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EZY40_RS07930	COG1882	Formate acetyltransferase
EZY40_RS07935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EZY40_RS07940	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EZY40_RS07945	COG1447	Phosphotransferase system cellobiose-specific component IIA
EZY40_RS07950	COG2390	Transcriptional regulator
EZY40_RS07955	COG1349	DNA-binding transcription factor activity
EZY40_RS07960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EZY40_RS07980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EZY40_RS07995	COG0564	pseudouridine synthase activity
EZY40_RS08025	COG0542	response to heat
EZY40_RS08030	COG4463	regulation of RNA biosynthetic process
EZY40_RS08045	COG0450	alkyl hydroperoxide reductase
EZY40_RS08060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EZY40_RS08070	COG3404	Formiminotransferase-cyclodeaminase
EZY40_RS08085	COG0531	amino acid
EZY40_RS08115	COG3590	peptidase
EZY40_RS08120	COG0366	Alpha amylase catalytic
EZY40_RS08125	COG1263	PTS System
EZY40_RS08125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EZY40_RS08130	COG2188	Transcriptional regulator
EZY40_RS08135	COG1733	regulation of RNA biosynthetic process
EZY40_RS08140	COG5433	transposase activity
EZY40_RS08145	COG2514	catechol 2,3-dioxygenase activity
EZY40_RS08155	COG0602	queuosine metabolic process
EZY40_RS08170	COG1328	CTP reductase activity
EZY40_RS08195	COG1393	Belongs to the ArsC family
EZY40_RS08210	COG0519	Catalyzes the synthesis of GMP from XMP
EZY40_RS08255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EZY40_RS08260	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EZY40_RS08265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EZY40_RS08345	COG1511	domain protein
EZY40_RS08365	COG5433	transposase activity
EZY40_RS08375	COG0305	Participates in initiation and elongation during chromosome replication
EZY40_RS08405	COG1760	l-serine dehydratase
EZY40_RS08410	COG1760	l-serine dehydratase
EZY40_RS08415	COG0741	lytic transglycosylase activity
EZY40_RS08420	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EZY40_RS08435	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EZY40_RS08445	COG0612	Peptidase, M16
EZY40_RS08470	COG0516	GMP reductase activity
EZY40_RS08470	COG0517	IMP dehydrogenase activity
EZY40_RS08480	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EZY40_RS08485	COG0488	(ABC) transporter
EZY40_RS08520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EZY40_RS08525	COG1475	DNA binding