locus-tag	class	description
B5D85_RS00010	COG0592	DNA-directed DNA polymerase activity
B5D85_RS00020	COG0012	GTP binding
B5D85_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B5D85_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B5D85_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B5D85_RS00065	COG0531	amino acid
B5D85_RS00240	COG3942	CHAP domain
B5D85_RS00260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B5D85_RS00270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B5D85_RS00285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B5D85_RS00305	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B5D85_RS00320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B5D85_RS00335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B5D85_RS00350	COG1012	belongs to the aldehyde dehydrogenase family
B5D85_RS00350	COG1454	alcohol dehydrogenase
B5D85_RS00355	COG1064	alcohol dehydrogenase
B5D85_RS00360	COG0534	Mate efflux family protein
B5D85_RS00470	COG0201	protein transport
B5D85_RS00590	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
B5D85_RS00615	COG1121	(ABC) transporter
B5D85_RS00620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B5D85_RS00635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5D85_RS00655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B5D85_RS00660	COG1459	type II secretion system
B5D85_RS00665	COG4537	Required for transformation and DNA binding
B5D85_RS00705	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B5D85_RS00710	COG1363	Peptidase, m42
B5D85_RS00725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5D85_RS00730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B5D85_RS00745	COG1428	Deoxynucleoside kinase
B5D85_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B5D85_RS00810	COG2031	fatty acid transporter
B5D85_RS00825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B5D85_RS00840	COG0251	oxidation-reduction process
B5D85_RS00855	COG1269	ATP hydrolysis coupled proton transport
B5D85_RS00860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
B5D85_RS00870	COG1527	subunit (C
B5D85_RS00875	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
B5D85_RS00910	COG1744	ABC transporter substrate-binding protein PnrA-like
B5D85_RS00950	COG0626	cystathionine gamma-synthase activity
B5D85_RS00980	COG3623	hexulose-6-phosphate isomerase
B5D85_RS01005	COG4175	Glycine betaine
B5D85_RS01005	COG3448	diguanylate cyclase activity
B5D85_RS01015	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5D85_RS01015	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
B5D85_RS01035	COG3969	phosphoadenosine phosphosulfate
B5D85_RS01040	COG1475	DNA binding
B5D85_RS01050	COG2801	Transposase and inactivated derivatives
B5D85_RS01065	COG0157	Belongs to the NadC ModD family
B5D85_RS01095	COG1268	BioY protein
B5D85_RS01100	COG1234	tRNA 3'-trailer cleavage
B5D85_RS01135	COG0457	Tetratricopeptide repeat
B5D85_RS01135	COG0705	Rhomboid family
B5D85_RS01155	COG1132	(ABC) transporter
B5D85_RS01160	COG1132	(ABC) transporter
B5D85_RS01170	COG0756	dUTP diphosphatase activity
B5D85_RS01195	COG3290	protein histidine kinase activity
B5D85_RS01220	COG1847	R3H domain protein
B5D85_RS01240	COG1175	transmembrane transport
B5D85_RS01245	COG0395	ABC-type sugar transport system, permease component
B5D85_RS01255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B5D85_RS01270	COG0084	hydrolase, TatD family'
B5D85_RS01295	COG1564	THIamine pyrophosphokinase
B5D85_RS01310	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
B5D85_RS01350	COG0765	amino acid transport
B5D85_RS01370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B5D85_RS01380	COG0719	Fe-S assembly protein
B5D85_RS01385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B5D85_RS01400	COG1686	Belongs to the peptidase S11 family
B5D85_RS01405	COG1686	Belongs to the peptidase S11 family
B5D85_RS01410	COG4166	transmembrane transport
B5D85_RS01415	COG0601	transmembrane transport
B5D85_RS01420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5D85_RS01425	COG0444	Belongs to the ABC transporter superfamily
B5D85_RS01435	COG2801	Transposase and inactivated derivatives
B5D85_RS01445	COG2801	Transposase and inactivated derivatives
B5D85_RS01490	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
B5D85_RS01495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
B5D85_RS01500	COG1534	Rna-binding protein
B5D85_RS01510	COG1713	HD superfamily hydrolase involved in NAD metabolism
B5D85_RS01515	COG0799	negative regulation of ribosome biogenesis
B5D85_RS01520	COG2226	methyltransferase
B5D85_RS01540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5D85_RS01545	COG1464	Belongs to the NlpA lipoprotein family
B5D85_RS01560	COG1114	Component of the transport system for branched-chain amino acids
B5D85_RS01570	COG0569	domain protein
B5D85_RS01575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B5D85_RS01585	COG1704	LemA family
B5D85_RS01600	COG0745	RESPONSE REGULATOR receiver
B5D85_RS01605	COG5002	protein histidine kinase activity
B5D85_RS01620	COG1484	DNA-dependent DNA replication
B5D85_RS01630	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
B5D85_RS01650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B5D85_RS01665	COG1254	Belongs to the acylphosphatase family
B5D85_RS01670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5D85_RS01725	COG1187	pseudouridine synthase activity
B5D85_RS01740	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
B5D85_RS01745	COG0671	phosphoesterase, PA-phosphatase related
B5D85_RS01750	COG1242	4 iron, 4 sulfur cluster binding
B5D85_RS01755	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
B5D85_RS01760	COG1253	flavin adenine dinucleotide binding
B5D85_RS01765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B5D85_RS01780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5D85_RS01785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B5D85_RS01790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
B5D85_RS01795	COG1120	ATPase activity
B5D85_RS01805	COG2244	polysaccharide biosynthetic process
B5D85_RS01835	COG0470	DNA polymerase III
B5D85_RS01865	COG1393	Belongs to the ArsC family
B5D85_RS01880	COG1609	Transcriptional regulator
B5D85_RS01885	COG0561	phosphatase activity
B5D85_RS01890	COG0708	Exodeoxyribonuclease III
B5D85_RS01900	COG1304	FMN binding
B5D85_RS01980	COG1028	Short-chain dehydrogenase reductase Sdr
B5D85_RS01985	COG0673	inositol 2-dehydrogenase activity
B5D85_RS02000	COG0494	nUDIX hydrolase
B5D85_RS02010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B5D85_RS02100	COG1702	phosphate starvation-inducible protein PhoH
B5D85_RS02105	COG1573	uracil-dna glycosylase
B5D85_RS02115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
B5D85_RS02210	COG0433	COG0433 Predicted ATPase
B5D85_RS02215	COG2814	Major facilitator Superfamily
B5D85_RS02230	COG0557	exoribonuclease II activity
B5D85_RS02260	COG0463	Glycosyl transferase, family 2
B5D85_RS02270	COG0778	Nitroreductase
B5D85_RS02275	COG0006	proline dipeptidase activity
B5D85_RS02280	COG1609	Transcriptional regulator
B5D85_RS02290	COG0438	transferase activity, transferring glycosyl groups
B5D85_RS02300	COG4555	ABC transporter
B5D85_RS02320	COG0183	Belongs to the thiolase family
B5D85_RS02335	COG0745	RESPONSE REGULATOR receiver
B5D85_RS02340	COG5002	protein histidine kinase activity
B5D85_RS02345	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
B5D85_RS02355	COG1196	nuclear chromosome segregation
B5D85_RS02365	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B5D85_RS02465	COG0561	phosphatase activity
B5D85_RS02470	COG0561	phosphatase activity
B5D85_RS02475	COG0552	protein localization to endoplasmic reticulum
B5D85_RS02480	COG0477	Major facilitator Superfamily
B5D85_RS02485	COG3711	transcriptional antiterminator
B5D85_RS02490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5D85_RS02490	COG1263	PTS System
B5D85_RS02490	COG2190	(PTS) system
B5D85_RS02500	COG3689	TIGRFAM TIGR03943 family protein
B5D85_RS02505	COG0701	Predicted permease
B5D85_RS02515	COG2183	response to ionizing radiation
B5D85_RS02560	COG0826	peptidase U32
B5D85_RS02565	COG4443	Transcriptional Coactivator p15 (PC4)
B5D85_RS02595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B5D85_RS02620	COG0386	Belongs to the glutathione peroxidase family
B5D85_RS02625	COG1164	Oligoendopeptidase f
B5D85_RS02635	COG0772	Belongs to the SEDS family
B5D85_RS02670	COG1078	dGTPase activity
B5D85_RS02685	COG1609	Transcriptional regulator
B5D85_RS02695	COG3716	PTS system mannose fructose sorbose family IID component
B5D85_RS02700	COG3715	PTS system
B5D85_RS02705	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5D85_RS02720	COG1028	Short-chain dehydrogenase reductase Sdr
B5D85_RS02735	COG0800	Aldolase
B5D85_RS02740	COG0546	phosphoglycolate phosphatase activity
B5D85_RS02745	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B5D85_RS02755	COG2884	Cell division ATP-binding protein ftsE
B5D85_RS02760	COG2177	Part of the ABC transporter FtsEX involved in
B5D85_RS02775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B5D85_RS02775	COG1199	ATP-dependent helicase activity
B5D85_RS02780	COG0436	Aminotransferase
B5D85_RS02890	COG3723	Recombinational DNA repair protein, rece pathway
B5D85_RS02965	COG1598	PFAM Uncharacterised protein family UPF0150
B5D85_RS03010	COG0740	serine-type endopeptidase activity
B5D85_RS03100	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5D85_RS03125	COG2188	Transcriptional regulator
B5D85_RS03130	COG2222	sugar isomerase
B5D85_RS03140	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
B5D85_RS03145	COG0716	FMN binding
B5D85_RS03155	COG0038	chloride channel
B5D85_RS03230	COG1131	(ABC) transporter
B5D85_RS03255	COG4708	membrane
B5D85_RS03265	COG1597	lipid kinase activity
B5D85_RS03350	COG0577	efflux transmembrane transporter activity
B5D85_RS03360	COG2321	neutral zinc metallopeptidase
B5D85_RS03375	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5D85_RS03385	COG1970	mechanosensitive ion channel activity
B5D85_RS03390	COG0358	DNA primase activity
B5D85_RS03395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B5D85_RS03400	COG2151	metal-sulfur cluster biosynthetic enzyme
B5D85_RS03445	COG1216	Glycosyl transferase, family 2
B5D85_RS03505	COG1368	sulfuric ester hydrolase activity
B5D85_RS03510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
B5D85_RS03530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B5D85_RS03535	COG0285	dihydrofolate synthase activity
B5D85_RS03545	COG1104	cysteine desulfurase activity
B5D85_RS03570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
B5D85_RS03580	COG0583	DNA-binding transcription factor activity
B5D85_RS03590	COG0564	pseudouridine synthase activity
B5D85_RS03595	COG5433	transposase activity
B5D85_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B5D85_RS03640	COG1136	(ABC) transporter
B5D85_RS03645	COG0577	efflux transmembrane transporter activity
B5D85_RS03660	COG1837	Belongs to the UPF0109 family
B5D85_RS03710	COG1349	DNA-binding transcription factor activity
B5D85_RS03715	COG1105	Belongs to the carbohydrate kinase PfkB family
B5D85_RS03720	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5D85_RS03720	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B5D85_RS03720	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5D85_RS03725	COG3942	CHAP domain
B5D85_RS03725	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5D85_RS03730	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5D85_RS03730	COG1388	LysM domain
B5D85_RS03770	COG0488	(ABC) transporter
B5D85_RS03785	COG0242	peptide deformylase activity
B5D85_RS03790	COG0737	Belongs to the 5'-nucleotidase family
B5D85_RS03795	COG2357	RelA SpoT domain protein
B5D85_RS03800	COG0745	RESPONSE REGULATOR receiver
B5D85_RS03835	COG3425	synthase
B5D85_RS03845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B5D85_RS03905	COG0583	DNA-binding transcription factor activity
B5D85_RS03930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5D85_RS03935	COG0765	amino acid transport
B5D85_RS03955	COG0187	DNA topoisomerase II activity
B5D85_RS03965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B5D85_RS03985	COG0539	negative regulation of cytoplasmic translation
B5D85_RS04030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B5D85_RS04035	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
B5D85_RS04045	COG0300	oxidoreductase activity
B5D85_RS04050	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
B5D85_RS04050	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B5D85_RS04065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B5D85_RS04070	COG2384	SAM-dependent methyltransferase
B5D85_RS04080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B5D85_RS04085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
B5D85_RS04095	COG1088	dTDP-glucose 4,6-dehydratase activity
B5D85_RS04100	COG0582	viral genome integration into host DNA
B5D85_RS04215	COG1783	phage Terminase large subunit
B5D85_RS04360	COG1051	belongs to the nudix hydrolase family
B5D85_RS04365	COG0628	permease
B5D85_RS04370	COG0457	Tetratricopeptide repeat
B5D85_RS04375	COG1293	RNA-binding protein homologous to eukaryotic snRNP
B5D85_RS04395	COG1129	ABC transporter
B5D85_RS04415	COG0488	(ABC) transporter
B5D85_RS04420	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B5D85_RS04425	COG0022	dehydrogenase e1 component
B5D85_RS04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
B5D85_RS04430	COG0508	dehydrogenase complex catalyzes the overall conversion of
B5D85_RS04445	COG1695	Transcriptional regulator
B5D85_RS04455	COG0095	Lipoate-protein ligase
B5D85_RS04460	COG3442	glutamine amidotransferase
B5D85_RS04465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5D85_RS04470	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
B5D85_RS04490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B5D85_RS04500	COG0647	UMP catabolic process
B5D85_RS04515	COG0105	UTP biosynthetic process
B5D85_RS04550	COG3715	PTS system
B5D85_RS04555	COG3716	PTS system mannose fructose sorbose family IID component
B5D85_RS04560	COG2972	Histidine kinase
B5D85_RS04565	COG4753	response regulator
B5D85_RS04565	COG2207	Transcriptional regulator
B5D85_RS04575	COG1012	belongs to the aldehyde dehydrogenase family
B5D85_RS04590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5D85_RS04670	COG1131	(ABC) transporter
B5D85_RS04715	COG0285	dihydrofolate synthase activity
B5D85_RS04735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B5D85_RS04750	COG1176	ABC-type spermidine putrescine transport system, permease component I
B5D85_RS04755	COG1177	transmembrane transport
B5D85_RS04765	COG4565	transcriptional regulatory protein
B5D85_RS04770	COG3290	protein histidine kinase activity
B5D85_RS04775	COG3493	citrate carrier protein
B5D85_RS04790	COG3700	Belongs to the class B bacterial acid phosphatase family
B5D85_RS04795	COG0038	chloride channel
B5D85_RS04805	COG0628	permease
B5D85_RS04815	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B5D85_RS04830	COG1104	cysteine desulfurase activity
B5D85_RS04845	COG2357	RelA SpoT domain protein
B5D85_RS04855	COG0564	pseudouridine synthase activity
B5D85_RS04860	COG0280	phosphate acetyltransferase
B5D85_RS04865	COG4221	oxidoreductase activity
B5D85_RS04880	COG1174	glycine betaine transport
B5D85_RS04900	COG2233	PERMEase
B5D85_RS04925	COG2890	protein-(glutamine-N5) methyltransferase activity
B5D85_RS04955	COG1132	(ABC) transporter
B5D85_RS04960	COG1132	(ABC) transporter
B5D85_RS04980	COG3764	Sortase (surface protein transpeptidase)
B5D85_RS04985	COG0346	lactoylglutathione lyase activity
B5D85_RS05005	COG1272	protein, Hemolysin III
B5D85_RS05025	COG0758	DNA mediated transformation
B5D85_RS05030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B5D85_RS05080	COG0511	ligase activity, forming carbon-carbon bonds
B5D85_RS05085	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B5D85_RS05100	COG2851	Citrate transporter
B5D85_RS05110	COG0511	ligase activity, forming carbon-carbon bonds
B5D85_RS05115	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
B5D85_RS05150	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
B5D85_RS05170	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B5D85_RS05180	COG2188	Transcriptional regulator
B5D85_RS05200	COG0488	(ABC) transporter
B5D85_RS05210	COG0351	phosphomethylpyrimidine kinase
B5D85_RS05210	COG0352	thiamine-phosphate diphosphorylase activity
B5D85_RS05215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B5D85_RS05225	COG1328	CTP reductase activity
B5D85_RS05225	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B5D85_RS05230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B5D85_RS05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B5D85_RS05270	COG0095	Lipoate-protein ligase
B5D85_RS05280	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B5D85_RS05285	COG4684	Psort location CytoplasmicMembrane, score
B5D85_RS05290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5D85_RS05295	COG1079	Belongs to the binding-protein-dependent transport system permease family
B5D85_RS05300	COG4603	Belongs to the binding-protein-dependent transport system permease family
B5D85_RS05305	COG3845	ABC transporter
B5D85_RS05310	COG1744	ABC transporter substrate-binding protein PnrA-like
B5D85_RS05315	COG0295	cytidine deaminase activity
B5D85_RS05320	COG2813	Specifically methylates the guanine in position
B5D85_RS05335	COG5002	protein histidine kinase activity
B5D85_RS05340	COG0745	RESPONSE REGULATOR receiver
B5D85_RS05350	COG0704	Plays a role in the regulation of phosphate uptake
B5D85_RS05365	COG0581	inorganic phosphate transmembrane transporter activity
B5D85_RS05370	COG0573	inorganic phosphate transmembrane transporter activity
B5D85_RS05380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B5D85_RS05380	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
B5D85_RS05385	COG0483	inositol monophosphate 1-phosphatase activity
B5D85_RS05400	COG0196	riboflavin kinase activity
B5D85_RS05430	COG1136	(ABC) transporter
B5D85_RS05430	COG4591	ABC-type transport system involved in lipoprotein release permease component
B5D85_RS05480	COG1115	amino acid carrier protein
B5D85_RS05485	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
B5D85_RS05495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5D85_RS05500	COG1126	abc transporter atp-binding protein
B5D85_RS05505	COG0765	amino acid transport
B5D85_RS05510	COG2824	Alkylphosphonate utilization operon protein PhnA
B5D85_RS05525	COG0469	pyruvate kinase activity
B5D85_RS05540	COG1725	Transcriptional regulator
B5D85_RS05545	COG1131	(ABC) transporter
B5D85_RS05570	COG0058	SHG alpha-glucan phosphorylase activity
B5D85_RS05575	COG1640	4-alpha-glucanotransferase
B5D85_RS05580	COG1609	Transcriptional regulator
B5D85_RS05585	COG2182	Extracellular solute-binding protein
B5D85_RS05590	COG1175	transmembrane transport
B5D85_RS05595	COG3833	ABC-type maltose transport systems, permease component
B5D85_RS05610	COG3833	ABC-type maltose transport systems, permease component
B5D85_RS05615	COG1175	transmembrane transport
B5D85_RS05625	COG0366	Alpha amylase catalytic
B5D85_RS05630	COG2182	Extracellular solute-binding protein
B5D85_RS05640	COG0657	acetylesterase activity
B5D85_RS05645	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
B5D85_RS05655	COG1696	Membrane protein involved in D-alanine export
B5D85_RS05675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B5D85_RS05680	COG1126	abc transporter atp-binding protein
B5D85_RS05685	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5D85_RS05695	COG1447	Phosphotransferase system cellobiose-specific component IIA
B5D85_RS05705	COG3711	transcriptional antiterminator
B5D85_RS05705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B5D85_RS05715	COG2723	6-phospho-beta-galactosidase activity
B5D85_RS05745	COG1187	pseudouridine synthase activity
B5D85_RS05755	COG2814	Major facilitator Superfamily
B5D85_RS05805	COG4109	DRTGG domain
B5D85_RS05810	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B5D85_RS05840	COG1028	Short-chain dehydrogenase reductase Sdr
B5D85_RS05855	COG0800	Aldolase
B5D85_RS05860	COG2186	Transcriptional regulator
B5D85_RS05865	COG3250	beta-galactosidase activity
B5D85_RS05875	COG2211	Major facilitator Superfamily
B5D85_RS05895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
B5D85_RS05895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
B5D85_RS05905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B5D85_RS05910	COG1956	GAF domain-containing protein
B5D85_RS05930	COG0513	Belongs to the DEAD box helicase family
B5D85_RS05935	COG0726	polysaccharide deacetylase
B5D85_RS05955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B5D85_RS05960	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B5D85_RS05990	COG1476	TRANSCRIPTIONal
B5D85_RS06005	COG4122	O-methyltransferase activity
B5D85_RS06010	COG2223	nitrite transmembrane transporter activity
B5D85_RS06025	COG1187	pseudouridine synthase activity
B5D85_RS06065	COG0658	competence protein
B5D85_RS06065	COG2333	competence protein COMEC
B5D85_RS06070	COG1555	photosystem II stabilization
B5D85_RS06070	COG1596	polysaccharide export
B5D85_RS06075	COG0204	Acyl-transferase
B5D85_RS06080	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
B5D85_RS06095	COG0513	Belongs to the DEAD box helicase family
B5D85_RS06115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B5D85_RS06130	COG0768	penicillin binding
B5D85_RS06135	COG2116	formate transmembrane transporter activity
B5D85_RS06145	COG1827	regulation of RNA biosynthetic process
B5D85_RS06160	COG2217	Heavy metal translocating P-type atpase
B5D85_RS06190	COG0860	N-Acetylmuramoyl-L-alanine amidase
B5D85_RS06190	COG1388	LysM domain
B5D85_RS06200	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5D85_RS06450	COG0582	viral genome integration into host DNA
B5D85_RS06465	COG2755	lipolytic protein G-D-S-L family
B5D85_RS06480	COG0497	DNA recombination
B5D85_RS06485	COG1438	arginine binding
B5D85_RS06490	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
B5D85_RS06515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B5D85_RS06520	COG0415	Belongs to the DNA photolyase family
B5D85_RS06530	COG0765	amino acid transport
B5D85_RS06535	COG4703	Protein of unknown function (DUF1797)
B5D85_RS06540	COG0542	response to heat
B5D85_RS06545	COG0494	nUDIX hydrolase
B5D85_RS06560	COG3599	regulation of cell shape
B5D85_RS06565	COG2302	S4 RNA-binding domain
B5D85_RS06580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B5D85_RS06615	COG1217	gtp-binding protein TYPA
B5D85_RS06620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B5D85_RS06625	COG1940	carbohydrate kinase activity
B5D85_RS06635	COG0783	Belongs to the Dps family
B5D85_RS06650	COG4470	Protein conserved in bacteria
B5D85_RS06655	COG1609	Transcriptional regulator
B5D85_RS06660	COG3480	Lon protease (S16) C-terminal proteolytic domain
B5D85_RS06670	COG0742	ribosomal rna small subunit methyltransferase
B5D85_RS06680	COG0549	Belongs to the carbamate kinase family
B5D85_RS06685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B5D85_RS06690	COG1288	antiporter activity
B5D85_RS06705	COG2235	arginine
B5D85_RS06730	COG2972	Histidine kinase
B5D85_RS06775	COG1388	LysM domain
B5D85_RS06775	COG0860	N-Acetylmuramoyl-L-alanine amidase
B5D85_RS06915	COG1475	DNA binding
B5D85_RS07020	COG3935	DnaD domain protein
B5D85_RS07055	COG3561	AntA/AntB antirepressor
B5D85_RS07065	COG1396	sequence-specific DNA binding
B5D85_RS07090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
B5D85_RS07095	COG0785	Cytochrome C biogenesis protein
B5D85_RS07100	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
B5D85_RS07105	COG1518	maintenance of DNA repeat elements
B5D85_RS07170	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
B5D85_RS07170	COG1605	Chorismate mutase
B5D85_RS07190	COG2226	methyltransferase
B5D85_RS07200	COG3250	beta-galactosidase activity
B5D85_RS07205	COG2207	Transcriptional regulator
B5D85_RS07205	COG4753	response regulator
B5D85_RS07210	COG2972	Histidine kinase
B5D85_RS07220	COG1653	transport
B5D85_RS07225	COG0395	ABC-type sugar transport system, permease component
B5D85_RS07230	COG1175	transmembrane transport
B5D85_RS07235	COG1940	carbohydrate kinase activity
B5D85_RS07240	COG2723	6-phospho-beta-galactosidase activity
B5D85_RS07245	COG3525	Glycosyl hydrolase, family 20, catalytic domain
B5D85_RS07260	COG0383	alpha-mannosidase activity
B5D85_RS07365	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
B5D85_RS07370	COG1739	Uncharacterized protein family UPF0029
B5D85_RS07380	COG1098	S1 RNA binding domain
B5D85_RS07390	COG2197	response regulator
B5D85_RS07395	COG4585	Histidine kinase
B5D85_RS07405	COG0515	serine threonine protein kinase
B5D85_RS07405	COG2815	serine threonine protein kinase
B5D85_RS07415	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B5D85_RS07415	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
B5D85_RS07425	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B5D85_RS07445	COG0583	DNA-binding transcription factor activity
B5D85_RS07450	COG0183	Belongs to the thiolase family
B5D85_RS07455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B5D85_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
B5D85_RS07470	COG2610	gluconate transmembrane transporter activity
B5D85_RS07485	COG0116	Belongs to the methyltransferase superfamily
B5D85_RS07510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5D85_RS07515	COG3579	cysteine-type endopeptidase activity
B5D85_RS07525	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
B5D85_RS07530	COG1113	amino acid transport
B5D85_RS07535	COG0492	ferredoxin-NADP+ reductase activity
B5D85_RS07545	COG1126	abc transporter atp-binding protein
B5D85_RS07555	COG0513	Belongs to the DEAD box helicase family
B5D85_RS07565	COG0768	penicillin binding
B5D85_RS07600	COG1131	(ABC) transporter
B5D85_RS07625	COG0446	pyridine nucleotide-disulphide oxidoreductase
B5D85_RS07630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5D85_RS07670	COG1755	Isoprenylcysteine carboxyl methyltransferase
B5D85_RS07685	COG1283	sodium-dependent phosphate transmembrane transporter activity
B5D85_RS07705	COG0561	phosphatase activity
B5D85_RS07710	COG2860	membrane
B5D85_RS07770	COG2217	Heavy metal translocating P-type atpase
B5D85_RS07800	COG2740	Nucleic-acid-binding protein implicated in transcription termination
B5D85_RS07805	COG0195	Participates in both transcription termination and antitermination
B5D85_RS07830	COG4473	ABC transporter
B5D85_RS07835	COG1131	(ABC) transporter
B5D85_RS07840	COG0537	adenosine 5'-monophosphoramidase activity
B5D85_RS07850	COG1316	TRANSCRIPTIONal
B5D85_RS07860	COG0802	atpase or kinase
B5D85_RS07865	COG2252	PERMEase
B5D85_RS07870	COG0561	phosphatase activity
B5D85_RS07880	COG3715	PTS system
B5D85_RS07885	COG3716	PTS system mannose fructose sorbose family IID component
B5D85_RS07910	COG0439	Biotin carboxylase
B5D85_RS07925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B5D85_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
B5D85_RS07935	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B5D85_RS07960	COG1024	Enoyl-CoA hydratase
B5D85_RS07965	COG0484	heat shock protein binding
B5D85_RS07995	COG0588	phosphoglycerate mutase activity
B5D85_RS08000	COG2261	transglycosylase associated protein
B5D85_RS08035	COG1335	isochorismatase
B5D85_RS08045	COG0436	Aminotransferase
B5D85_RS08055	COG0561	phosphatase activity
B5D85_RS08060	COG0252	asparaginase activity
B5D85_RS08075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B5D85_RS08085	COG1129	ABC transporter
B5D85_RS08100	COG1132	(ABC) transporter
B5D85_RS08105	COG4988	ABC transporter
B5D85_RS08110	COG1120	ATPase activity
B5D85_RS08135	COG3942	CHAP domain
B5D85_RS08135	COG1388	LysM domain
B5D85_RS08160	COG5433	transposase activity
B5D85_RS08165	COG1482	cell wall glycoprotein biosynthetic process
B5D85_RS08170	COG1940	carbohydrate kinase activity
B5D85_RS08180	COG2190	(PTS) system
B5D85_RS08180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5D85_RS08180	COG1263	PTS System
B5D85_RS08185	COG1621	beta-fructofuranosidase activity
B5D85_RS08190	COG1609	Transcriptional regulator
B5D85_RS08210	COG2131	deaminase
B5D85_RS08215	COG0006	proline dipeptidase activity
B5D85_RS08255	COG1194	a g-specific adenine glycosylase
B5D85_RS08265	COG3118	belongs to the thioredoxin family
B5D85_RS08295	COG0681	Belongs to the peptidase S26 family
B5D85_RS08300	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B5D85_RS08315	COG1882	Formate acetyltransferase
B5D85_RS08320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B5D85_RS08335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B5D85_RS08345	COG2814	Major facilitator Superfamily
B5D85_RS08350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B5D85_RS08375	COG0789	Transcriptional regulator
B5D85_RS08410	COG2081	HI0933 family
B5D85_RS08420	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
B5D85_RS08425	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
B5D85_RS08445	COG0456	acetyltransferase
B5D85_RS08450	COG1214	PFAM Peptidase M22, glycoprotease
B5D85_RS08465	COG0174	glutamine synthetase
B5D85_RS08470	COG0789	Transcriptional regulator
B5D85_RS08485	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
B5D85_RS08540	COG0668	transmembrane transport
B5D85_RS08550	COG4720	Psort location CytoplasmicMembrane, score
B5D85_RS08555	COG0351	phosphomethylpyrimidine kinase
B5D85_RS08600	COG1929	Belongs to the glycerate kinase type-1 family
B5D85_RS08605	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B5D85_RS08635	COG0577	efflux transmembrane transporter activity
B5D85_RS08640	COG1136	(ABC) transporter
B5D85_RS08665	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5D85_RS08665	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5D85_RS08670	COG1447	Phosphotransferase system cellobiose-specific component IIA
B5D85_RS08730	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
B5D85_RS08735	COG1476	TRANSCRIPTIONal
B5D85_RS08755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B5D85_RS08765	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
B5D85_RS08785	COG1045	serine acetyltransferase
B5D85_RS08800	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B5D85_RS08815	COG3711	transcriptional antiterminator
B5D85_RS08840	COG0431	NADPH-dependent FMN reductase
B5D85_RS08845	COG1846	Transcriptional regulator
B5D85_RS08865	COG4589	Belongs to the CDS family
B5D85_RS08875	COG1862	Preprotein translocase
B5D85_RS08885	COG1523	belongs to the glycosyl hydrolase 13 family
B5D85_RS08900	COG3842	ATPase activity
B5D85_RS08940	COG2190	(PTS) system
B5D85_RS08940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5D85_RS08940	COG1263	PTS System
B5D85_RS08945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B5D85_RS08965	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B5D85_RS08970	COG0512	Glutamine amidotransferase of anthranilate synthase
B5D85_RS08975	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B5D85_RS09005	COG0601	transmembrane transport
B5D85_RS09010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B5D85_RS09015	COG1122	ATPase activity
B5D85_RS09035	COG0803	Belongs to the bacterial solute-binding protein 9 family
B5D85_RS09045	COG1404	Belongs to the peptidase S8 family
B5D85_RS09045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B5D85_RS09065	COG3711	transcriptional antiterminator
B5D85_RS09080	COG1705	Flagellar rod assembly protein muramidase FlgJ
B5D85_RS09080	COG3942	CHAP domain
B5D85_RS09085	COG2205	protein histidine kinase activity
B5D85_RS09090	COG0745	RESPONSE REGULATOR receiver
B5D85_RS09095	COG0577	efflux transmembrane transporter activity
B5D85_RS09100	COG1136	(ABC) transporter
B5D85_RS09175	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B5D85_RS09190	COG1882	Formate acetyltransferase
B5D85_RS09195	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5D85_RS09200	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
B5D85_RS09205	COG1447	Phosphotransferase system cellobiose-specific component IIA
B5D85_RS09210	COG2390	Transcriptional regulator
B5D85_RS09215	COG1349	DNA-binding transcription factor activity
B5D85_RS09220	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
B5D85_RS09240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B5D85_RS09255	COG0564	pseudouridine synthase activity
B5D85_RS09290	COG0542	response to heat
B5D85_RS09295	COG4463	regulation of RNA biosynthetic process
B5D85_RS09310	COG0450	alkyl hydroperoxide reductase
B5D85_RS09325	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
B5D85_RS09335	COG3404	Formiminotransferase-cyclodeaminase
B5D85_RS09350	COG0531	amino acid
B5D85_RS09380	COG3590	peptidase
B5D85_RS09385	COG0366	Alpha amylase catalytic
B5D85_RS09390	COG1263	PTS System
B5D85_RS09390	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B5D85_RS09395	COG2188	Transcriptional regulator
B5D85_RS09405	COG1733	regulation of RNA biosynthetic process
B5D85_RS09410	COG2514	catechol 2,3-dioxygenase activity
B5D85_RS09420	COG0602	queuosine metabolic process
B5D85_RS09440	COG1328	CTP reductase activity
B5D85_RS09465	COG1393	Belongs to the ArsC family
B5D85_RS09480	COG0519	Catalyzes the synthesis of GMP from XMP
B5D85_RS09525	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B5D85_RS09530	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B5D85_RS09535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B5D85_RS09620	COG1511	domain protein
B5D85_RS09640	COG0305	Participates in initiation and elongation during chromosome replication
B5D85_RS09670	COG1760	l-serine dehydratase
B5D85_RS09675	COG1760	l-serine dehydratase
B5D85_RS09680	COG0741	lytic transglycosylase activity
B5D85_RS09685	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
B5D85_RS09700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B5D85_RS09710	COG0612	Peptidase, M16
B5D85_RS09755	COG0517	IMP dehydrogenase activity
B5D85_RS09755	COG0516	GMP reductase activity
B5D85_RS09765	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
B5D85_RS09770	COG0488	(ABC) transporter
B5D85_RS09815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B5D85_RS09820	COG1475	DNA binding