locus-tag	class	description
EB816_RS00010	COG0592	DNA-directed DNA polymerase activity
EB816_RS00020	COG0012	GTP binding
EB816_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EB816_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EB816_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EB816_RS00065	COG0531	amino acid
EB816_RS00250	COG3942	CHAP domain
EB816_RS00270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EB816_RS00280	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EB816_RS00295	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EB816_RS00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EB816_RS00330	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EB816_RS00345	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EB816_RS00360	COG1012	belongs to the aldehyde dehydrogenase family
EB816_RS00360	COG1454	alcohol dehydrogenase
EB816_RS00365	COG1064	alcohol dehydrogenase
EB816_RS00370	COG0534	Mate efflux family protein
EB816_RS00480	COG0201	protein transport
EB816_RS00625	COG1121	(ABC) transporter
EB816_RS00630	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EB816_RS00645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB816_RS00665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EB816_RS00670	COG1459	type II secretion system
EB816_RS00675	COG4537	Required for transformation and DNA binding
EB816_RS00715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EB816_RS00720	COG1363	Peptidase, m42
EB816_RS00735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB816_RS00740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EB816_RS00750	COG1428	Deoxynucleoside kinase
EB816_RS00755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EB816_RS00800	COG4509	Sortase family
EB816_RS00825	COG2031	fatty acid transporter
EB816_RS00840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EB816_RS00855	COG0251	oxidation-reduction process
EB816_RS00870	COG1269	ATP hydrolysis coupled proton transport
EB816_RS00875	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EB816_RS00885	COG1527	subunit (C
EB816_RS00890	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
EB816_RS00925	COG1744	ABC transporter substrate-binding protein PnrA-like
EB816_RS00970	COG0626	cystathionine gamma-synthase activity
EB816_RS01000	COG3623	hexulose-6-phosphate isomerase
EB816_RS01025	COG4175	Glycine betaine
EB816_RS01025	COG3448	diguanylate cyclase activity
EB816_RS01035	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB816_RS01035	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EB816_RS01055	COG3969	phosphoadenosine phosphosulfate
EB816_RS01060	COG1475	DNA binding
EB816_RS01085	COG0157	Belongs to the NadC ModD family
EB816_RS01115	COG1268	BioY protein
EB816_RS01120	COG1234	tRNA 3'-trailer cleavage
EB816_RS01165	COG2274	protein secretion by the type I secretion system
EB816_RS01170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB816_RS01200	COG0457	Tetratricopeptide repeat
EB816_RS01200	COG0705	Rhomboid family
EB816_RS01220	COG1132	(ABC) transporter
EB816_RS01225	COG1132	(ABC) transporter
EB816_RS01235	COG0756	dUTP diphosphatase activity
EB816_RS01260	COG3290	protein histidine kinase activity
EB816_RS01285	COG1847	R3H domain protein
EB816_RS01305	COG1175	transmembrane transport
EB816_RS01310	COG0395	ABC-type sugar transport system, permease component
EB816_RS01320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EB816_RS01335	COG0084	hydrolase, TatD family'
EB816_RS01360	COG1564	THIamine pyrophosphokinase
EB816_RS01375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EB816_RS01415	COG0765	amino acid transport
EB816_RS01435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EB816_RS01445	COG0719	Fe-S assembly protein
EB816_RS01450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EB816_RS01465	COG1686	Belongs to the peptidase S11 family
EB816_RS01470	COG1686	Belongs to the peptidase S11 family
EB816_RS01475	COG4166	transmembrane transport
EB816_RS01480	COG0601	transmembrane transport
EB816_RS01485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EB816_RS01490	COG0444	Belongs to the ABC transporter superfamily
EB816_RS01545	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EB816_RS01550	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EB816_RS01555	COG1534	Rna-binding protein
EB816_RS01565	COG1713	HD superfamily hydrolase involved in NAD metabolism
EB816_RS01570	COG0799	negative regulation of ribosome biogenesis
EB816_RS01575	COG2226	methyltransferase
EB816_RS01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB816_RS01600	COG1464	Belongs to the NlpA lipoprotein family
EB816_RS01615	COG1114	Component of the transport system for branched-chain amino acids
EB816_RS01625	COG0569	domain protein
EB816_RS01630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EB816_RS01640	COG1704	LemA family
EB816_RS01655	COG0745	RESPONSE REGULATOR receiver
EB816_RS01675	COG1484	DNA-dependent DNA replication
EB816_RS01685	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EB816_RS01705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EB816_RS01720	COG1254	Belongs to the acylphosphatase family
EB816_RS01725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB816_RS01780	COG1187	pseudouridine synthase activity
EB816_RS01795	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EB816_RS01800	COG0671	phosphoesterase, PA-phosphatase related
EB816_RS01805	COG1242	4 iron, 4 sulfur cluster binding
EB816_RS01810	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EB816_RS01815	COG1253	flavin adenine dinucleotide binding
EB816_RS01820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EB816_RS01835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB816_RS01840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EB816_RS01845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EB816_RS01850	COG1120	ATPase activity
EB816_RS01860	COG2244	polysaccharide biosynthetic process
EB816_RS01895	COG0470	DNA polymerase III
EB816_RS01925	COG1393	Belongs to the ArsC family
EB816_RS01930	COG0708	Exodeoxyribonuclease III
EB816_RS01940	COG1304	FMN binding
EB816_RS02045	COG1028	Short-chain dehydrogenase reductase Sdr
EB816_RS02050	COG0673	inositol 2-dehydrogenase activity
EB816_RS02065	COG0494	nUDIX hydrolase
EB816_RS02075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EB816_RS02165	COG1702	phosphate starvation-inducible protein PhoH
EB816_RS02170	COG1573	uracil-dna glycosylase
EB816_RS02180	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EB816_RS02270	COG0433	COG0433 Predicted ATPase
EB816_RS02275	COG2814	Major facilitator Superfamily
EB816_RS02290	COG0557	exoribonuclease II activity
EB816_RS02320	COG0463	Glycosyl transferase, family 2
EB816_RS02330	COG0778	Nitroreductase
EB816_RS02335	COG0006	proline dipeptidase activity
EB816_RS02340	COG1609	Transcriptional regulator
EB816_RS02350	COG0438	transferase activity, transferring glycosyl groups
EB816_RS02360	COG4555	ABC transporter
EB816_RS02380	COG0183	Belongs to the thiolase family
EB816_RS02395	COG0745	RESPONSE REGULATOR receiver
EB816_RS02400	COG5002	protein histidine kinase activity
EB816_RS02405	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EB816_RS02415	COG1196	nuclear chromosome segregation
EB816_RS02425	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EB816_RS02515	COG4695	Portal protein
EB816_RS02570	COG0561	phosphatase activity
EB816_RS02575	COG0561	phosphatase activity
EB816_RS02580	COG0552	protein localization to endoplasmic reticulum
EB816_RS02585	COG0477	Major facilitator Superfamily
EB816_RS02590	COG3711	transcriptional antiterminator
EB816_RS02595	COG1263	PTS System
EB816_RS02595	COG2190	(PTS) system
EB816_RS02595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB816_RS02605	COG3689	TIGRFAM TIGR03943 family protein
EB816_RS02610	COG0701	Predicted permease
EB816_RS02620	COG2183	response to ionizing radiation
EB816_RS02665	COG0826	peptidase U32
EB816_RS02670	COG4443	Transcriptional Coactivator p15 (PC4)
EB816_RS02715	COG0386	Belongs to the glutathione peroxidase family
EB816_RS02720	COG1164	Oligoendopeptidase f
EB816_RS02730	COG0772	Belongs to the SEDS family
EB816_RS02765	COG1078	dGTPase activity
EB816_RS02780	COG1609	Transcriptional regulator
EB816_RS02790	COG3716	PTS system mannose fructose sorbose family IID component
EB816_RS02795	COG3715	PTS system
EB816_RS02800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB816_RS02815	COG1028	Short-chain dehydrogenase reductase Sdr
EB816_RS02830	COG0800	Aldolase
EB816_RS02835	COG0546	phosphoglycolate phosphatase activity
EB816_RS02850	COG2884	Cell division ATP-binding protein ftsE
EB816_RS02855	COG2177	Part of the ABC transporter FtsEX involved in
EB816_RS02870	COG1199	ATP-dependent helicase activity
EB816_RS02870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EB816_RS02875	COG0436	Aminotransferase
EB816_RS02910	COG2188	Transcriptional regulator
EB816_RS02915	COG2222	sugar isomerase
EB816_RS02925	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EB816_RS02930	COG0716	FMN binding
EB816_RS02940	COG0038	chloride channel
EB816_RS02955	COG0582	viral genome integration into host DNA
EB816_RS03095	COG1475	DNA binding
EB816_RS03240	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB816_RS03330	COG1131	(ABC) transporter
EB816_RS03355	COG4708	membrane
EB816_RS03365	COG1597	lipid kinase activity
EB816_RS03450	COG0577	efflux transmembrane transporter activity
EB816_RS03460	COG2321	neutral zinc metallopeptidase
EB816_RS03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB816_RS03485	COG1970	mechanosensitive ion channel activity
EB816_RS03490	COG0358	DNA primase activity
EB816_RS03495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EB816_RS03500	COG2151	metal-sulfur cluster biosynthetic enzyme
EB816_RS03545	COG1216	Glycosyl transferase, family 2
EB816_RS03605	COG1368	sulfuric ester hydrolase activity
EB816_RS03610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EB816_RS03630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EB816_RS03635	COG0285	dihydrofolate synthase activity
EB816_RS03645	COG1104	cysteine desulfurase activity
EB816_RS03670	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EB816_RS03680	COG0583	DNA-binding transcription factor activity
EB816_RS03690	COG0564	pseudouridine synthase activity
EB816_RS03725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EB816_RS03730	COG1136	(ABC) transporter
EB816_RS03735	COG0577	efflux transmembrane transporter activity
EB816_RS03740	COG0584	glycerophosphoryl diester phosphodiesterase
EB816_RS03750	COG1837	Belongs to the UPF0109 family
EB816_RS03800	COG1349	DNA-binding transcription factor activity
EB816_RS03805	COG1105	Belongs to the carbohydrate kinase PfkB family
EB816_RS03810	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB816_RS03810	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB816_RS03810	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EB816_RS03815	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB816_RS03815	COG1388	LysM domain
EB816_RS03820	COG1388	LysM domain
EB816_RS03820	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB816_RS03845	COG0105	UTP biosynthetic process
EB816_RS03865	COG0488	(ABC) transporter
EB816_RS03875	COG0242	peptide deformylase activity
EB816_RS03880	COG0737	Belongs to the 5'-nucleotidase family
EB816_RS03885	COG2357	RelA SpoT domain protein
EB816_RS03890	COG0745	RESPONSE REGULATOR receiver
EB816_RS03925	COG3425	synthase
EB816_RS03935	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EB816_RS03995	COG0583	DNA-binding transcription factor activity
EB816_RS04020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB816_RS04025	COG0765	amino acid transport
EB816_RS04045	COG0187	DNA topoisomerase II activity
EB816_RS04060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EB816_RS04080	COG0539	negative regulation of cytoplasmic translation
EB816_RS04125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EB816_RS04130	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
EB816_RS04140	COG0300	oxidoreductase activity
EB816_RS04145	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EB816_RS04145	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EB816_RS04160	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EB816_RS04165	COG2384	SAM-dependent methyltransferase
EB816_RS04175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EB816_RS04180	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EB816_RS04190	COG1088	dTDP-glucose 4,6-dehydratase activity
EB816_RS04195	COG1051	belongs to the nudix hydrolase family
EB816_RS04200	COG0628	permease
EB816_RS04205	COG0457	Tetratricopeptide repeat
EB816_RS04210	COG1293	RNA-binding protein homologous to eukaryotic snRNP
EB816_RS04230	COG1129	ABC transporter
EB816_RS04250	COG0488	(ABC) transporter
EB816_RS04255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EB816_RS04260	COG0022	dehydrogenase e1 component
EB816_RS04260	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB816_RS04265	COG0508	dehydrogenase complex catalyzes the overall conversion of
EB816_RS04285	COG5492	domain, Protein
EB816_RS04290	COG0095	Lipoate-protein ligase
EB816_RS04295	COG3442	glutamine amidotransferase
EB816_RS04300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EB816_RS04305	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EB816_RS04325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EB816_RS04335	COG0647	UMP catabolic process
EB816_RS04350	COG0105	UTP biosynthetic process
EB816_RS04390	COG3715	PTS system
EB816_RS04395	COG3716	PTS system mannose fructose sorbose family IID component
EB816_RS04400	COG2972	Histidine kinase
EB816_RS04405	COG4753	response regulator
EB816_RS04405	COG2207	Transcriptional regulator
EB816_RS04415	COG1012	belongs to the aldehyde dehydrogenase family
EB816_RS04430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB816_RS04460	COG0285	dihydrofolate synthase activity
EB816_RS04495	COG1176	ABC-type spermidine putrescine transport system, permease component I
EB816_RS04500	COG1177	transmembrane transport
EB816_RS04510	COG4565	transcriptional regulatory protein
EB816_RS04515	COG3290	protein histidine kinase activity
EB816_RS04520	COG3493	citrate carrier protein
EB816_RS04535	COG3700	Belongs to the class B bacterial acid phosphatase family
EB816_RS04540	COG0038	chloride channel
EB816_RS04550	COG0628	permease
EB816_RS04560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EB816_RS04575	COG1104	cysteine desulfurase activity
EB816_RS04590	COG2357	RelA SpoT domain protein
EB816_RS04600	COG0564	pseudouridine synthase activity
EB816_RS04605	COG0280	phosphate acetyltransferase
EB816_RS04610	COG4221	oxidoreductase activity
EB816_RS04625	COG1174	glycine betaine transport
EB816_RS04645	COG2233	PERMEase
EB816_RS04670	COG2890	protein-(glutamine-N5) methyltransferase activity
EB816_RS04700	COG1132	(ABC) transporter
EB816_RS04705	COG1132	(ABC) transporter
EB816_RS04725	COG3764	Sortase (surface protein transpeptidase)
EB816_RS04730	COG0346	lactoylglutathione lyase activity
EB816_RS04750	COG1272	protein, Hemolysin III
EB816_RS04770	COG0758	DNA mediated transformation
EB816_RS04775	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB816_RS04825	COG0511	ligase activity, forming carbon-carbon bonds
EB816_RS04830	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EB816_RS04845	COG2851	Citrate transporter
EB816_RS04855	COG0511	ligase activity, forming carbon-carbon bonds
EB816_RS04860	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EB816_RS04890	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
EB816_RS04910	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EB816_RS04920	COG2188	Transcriptional regulator
EB816_RS04940	COG0488	(ABC) transporter
EB816_RS04950	COG0351	phosphomethylpyrimidine kinase
EB816_RS04950	COG0352	thiamine-phosphate diphosphorylase activity
EB816_RS04955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EB816_RS04965	COG1328	CTP reductase activity
EB816_RS04965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EB816_RS04970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EB816_RS05000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EB816_RS05020	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EB816_RS05025	COG4684	Psort location CytoplasmicMembrane, score
EB816_RS05030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB816_RS05035	COG1079	Belongs to the binding-protein-dependent transport system permease family
EB816_RS05040	COG4603	Belongs to the binding-protein-dependent transport system permease family
EB816_RS05045	COG3845	ABC transporter
EB816_RS05050	COG1744	ABC transporter substrate-binding protein PnrA-like
EB816_RS05055	COG0295	cytidine deaminase activity
EB816_RS05060	COG2813	Specifically methylates the guanine in position
EB816_RS05075	COG5002	protein histidine kinase activity
EB816_RS05080	COG0745	RESPONSE REGULATOR receiver
EB816_RS05095	COG0704	Plays a role in the regulation of phosphate uptake
EB816_RS05110	COG0581	inorganic phosphate transmembrane transporter activity
EB816_RS05115	COG0573	inorganic phosphate transmembrane transporter activity
EB816_RS05125	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EB816_RS05125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB816_RS05130	COG0483	inositol monophosphate 1-phosphatase activity
EB816_RS05145	COG0196	riboflavin kinase activity
EB816_RS05175	COG1136	(ABC) transporter
EB816_RS05175	COG4591	ABC-type transport system involved in lipoprotein release permease component
EB816_RS05225	COG1115	amino acid carrier protein
EB816_RS05230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EB816_RS05240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB816_RS05245	COG1126	abc transporter atp-binding protein
EB816_RS05250	COG0765	amino acid transport
EB816_RS05255	COG2824	Alkylphosphonate utilization operon protein PhnA
EB816_RS05265	COG0681	Belongs to the peptidase S26 family
EB816_RS05270	COG0469	pyruvate kinase activity
EB816_RS05285	COG1725	Transcriptional regulator
EB816_RS05290	COG1131	(ABC) transporter
EB816_RS05410	COG0740	serine-type endopeptidase activity
EB816_RS05620	COG0058	SHG alpha-glucan phosphorylase activity
EB816_RS05625	COG1640	4-alpha-glucanotransferase
EB816_RS05630	COG1609	Transcriptional regulator
EB816_RS05635	COG2182	Extracellular solute-binding protein
EB816_RS05640	COG1175	transmembrane transport
EB816_RS05645	COG3833	ABC-type maltose transport systems, permease component
EB816_RS05660	COG3833	ABC-type maltose transport systems, permease component
EB816_RS05665	COG1175	transmembrane transport
EB816_RS05675	COG0366	Alpha amylase catalytic
EB816_RS05680	COG2182	Extracellular solute-binding protein
EB816_RS05690	COG0657	acetylesterase activity
EB816_RS05695	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EB816_RS05705	COG1696	Membrane protein involved in D-alanine export
EB816_RS05725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EB816_RS05730	COG1126	abc transporter atp-binding protein
EB816_RS05735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB816_RS05745	COG1447	Phosphotransferase system cellobiose-specific component IIA
EB816_RS05755	COG3711	transcriptional antiterminator
EB816_RS05755	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EB816_RS05765	COG2723	6-phospho-beta-galactosidase activity
EB816_RS05795	COG1187	pseudouridine synthase activity
EB816_RS05805	COG2814	Major facilitator Superfamily
EB816_RS05850	COG0534	Mate efflux family protein
EB816_RS05855	COG1129	ABC transporter
EB816_RS05870	COG1132	(ABC) transporter
EB816_RS05875	COG2375	cellular response to nickel ion
EB816_RS05875	COG1132	(ABC) transporter
EB816_RS05920	COG4443	Transcriptional Coactivator p15 (PC4)
EB816_RS05925	COG1475	DNA binding
EB816_RS05990	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EB816_RS05990	COG0551	DNA topoisomerase type I activity
EB816_RS06200	COG1484	DNA-dependent DNA replication
EB816_RS06250	COG4109	DRTGG domain
EB816_RS06255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EB816_RS06285	COG1028	Short-chain dehydrogenase reductase Sdr
EB816_RS06290	COG1312	Catalyzes the dehydration of D-mannonate
EB816_RS06300	COG0800	Aldolase
EB816_RS06305	COG2186	Transcriptional regulator
EB816_RS06310	COG3250	beta-galactosidase activity
EB816_RS06320	COG2211	Major facilitator Superfamily
EB816_RS06340	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EB816_RS06340	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EB816_RS06350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EB816_RS06355	COG1956	GAF domain-containing protein
EB816_RS06375	COG0513	Belongs to the DEAD box helicase family
EB816_RS06380	COG0726	polysaccharide deacetylase
EB816_RS06400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EB816_RS06405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EB816_RS06440	COG1476	TRANSCRIPTIONal
EB816_RS06455	COG4122	O-methyltransferase activity
EB816_RS06460	COG2223	nitrite transmembrane transporter activity
EB816_RS06475	COG1187	pseudouridine synthase activity
EB816_RS06520	COG2333	competence protein COMEC
EB816_RS06520	COG0658	competence protein
EB816_RS06525	COG1555	photosystem II stabilization
EB816_RS06525	COG1596	polysaccharide export
EB816_RS06530	COG0204	Acyl-transferase
EB816_RS06535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EB816_RS06550	COG0513	Belongs to the DEAD box helicase family
EB816_RS06570	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EB816_RS06590	COG2116	formate transmembrane transporter activity
EB816_RS06600	COG1827	regulation of RNA biosynthetic process
EB816_RS06615	COG2217	Heavy metal translocating P-type atpase
EB816_RS06630	COG2755	lipolytic protein G-D-S-L family
EB816_RS06645	COG0497	DNA recombination
EB816_RS06650	COG1438	arginine binding
EB816_RS06655	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EB816_RS06680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EB816_RS06685	COG0415	Belongs to the DNA photolyase family
EB816_RS06695	COG0765	amino acid transport
EB816_RS06700	COG4703	Protein of unknown function (DUF1797)
EB816_RS06705	COG0542	response to heat
EB816_RS06710	COG0494	nUDIX hydrolase
EB816_RS06725	COG3599	regulation of cell shape
EB816_RS06730	COG2302	S4 RNA-binding domain
EB816_RS06745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EB816_RS06770	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EB816_RS06780	COG1217	gtp-binding protein TYPA
EB816_RS06785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EB816_RS06790	COG1940	carbohydrate kinase activity
EB816_RS06800	COG0783	Belongs to the Dps family
EB816_RS06815	COG4470	Protein conserved in bacteria
EB816_RS06820	COG1609	Transcriptional regulator
EB816_RS06825	COG3480	Lon protease (S16) C-terminal proteolytic domain
EB816_RS06835	COG0742	ribosomal rna small subunit methyltransferase
EB816_RS06845	COG0549	Belongs to the carbamate kinase family
EB816_RS06850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EB816_RS06855	COG1288	antiporter activity
EB816_RS06870	COG2235	arginine
EB816_RS06895	COG2972	Histidine kinase
EB816_RS06910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EB816_RS06915	COG0785	Cytochrome C biogenesis protein
EB816_RS06925	COG0673	inositol 2-dehydrogenase activity
EB816_RS06930	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EB816_RS07025	COG0433	COG0433 Predicted ATPase
EB816_RS07075	COG1674	ftsk spoiiie
EB816_RS07115	COG1396	sequence-specific DNA binding
EB816_RS07155	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EB816_RS07155	COG1605	Chorismate mutase
EB816_RS07175	COG2226	methyltransferase
EB816_RS07185	COG3250	beta-galactosidase activity
EB816_RS07190	COG2207	Transcriptional regulator
EB816_RS07190	COG4753	response regulator
EB816_RS07195	COG2972	Histidine kinase
EB816_RS07205	COG1653	transport
EB816_RS07210	COG0395	ABC-type sugar transport system, permease component
EB816_RS07215	COG1175	transmembrane transport
EB816_RS07220	COG1940	carbohydrate kinase activity
EB816_RS07225	COG2723	6-phospho-beta-galactosidase activity
EB816_RS07230	COG3525	Glycosyl hydrolase, family 20, catalytic domain
EB816_RS07245	COG0383	alpha-mannosidase activity
EB816_RS07355	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EB816_RS07360	COG1739	Uncharacterized protein family UPF0029
EB816_RS07370	COG1098	S1 RNA binding domain
EB816_RS07380	COG2197	response regulator
EB816_RS07385	COG4585	Histidine kinase
EB816_RS07395	COG2815	serine threonine protein kinase
EB816_RS07395	COG0515	serine threonine protein kinase
EB816_RS07405	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EB816_RS07405	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EB816_RS07415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EB816_RS07435	COG0583	DNA-binding transcription factor activity
EB816_RS07440	COG0183	Belongs to the thiolase family
EB816_RS07445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EB816_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
EB816_RS07460	COG2610	gluconate transmembrane transporter activity
EB816_RS07475	COG0116	Belongs to the methyltransferase superfamily
EB816_RS07500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB816_RS07505	COG3579	cysteine-type endopeptidase activity
EB816_RS07515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EB816_RS07520	COG1113	amino acid transport
EB816_RS07525	COG0492	ferredoxin-NADP+ reductase activity
EB816_RS07535	COG1126	abc transporter atp-binding protein
EB816_RS07545	COG0513	Belongs to the DEAD box helicase family
EB816_RS07555	COG0768	penicillin binding
EB816_RS07590	COG1131	(ABC) transporter
EB816_RS07615	COG0446	pyridine nucleotide-disulphide oxidoreductase
EB816_RS07620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB816_RS07660	COG1755	Isoprenylcysteine carboxyl methyltransferase
EB816_RS07665	COG0656	L-ascorbic acid biosynthetic process
EB816_RS07675	COG1283	sodium-dependent phosphate transmembrane transporter activity
EB816_RS07695	COG0561	phosphatase activity
EB816_RS07700	COG2860	membrane
EB816_RS07760	COG2217	Heavy metal translocating P-type atpase
EB816_RS07790	COG2740	Nucleic-acid-binding protein implicated in transcription termination
EB816_RS07795	COG0195	Participates in both transcription termination and antitermination
EB816_RS07815	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB816_RS07935	COG1783	phage Terminase large subunit
EB816_RS08055	COG4974	Belongs to the 'phage' integrase family
EB816_RS08075	COG4473	ABC transporter
EB816_RS08080	COG1131	(ABC) transporter
EB816_RS08085	COG0537	adenosine 5'-monophosphoramidase activity
EB816_RS08095	COG1316	TRANSCRIPTIONal
EB816_RS08105	COG0802	atpase or kinase
EB816_RS08110	COG2252	PERMEase
EB816_RS08115	COG0561	phosphatase activity
EB816_RS08125	COG3715	PTS system
EB816_RS08130	COG3716	PTS system mannose fructose sorbose family IID component
EB816_RS08155	COG0439	Biotin carboxylase
EB816_RS08170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EB816_RS08175	COG1028	Short-chain dehydrogenase reductase Sdr
EB816_RS08180	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EB816_RS08205	COG1024	Enoyl-CoA hydratase
EB816_RS08210	COG0484	heat shock protein binding
EB816_RS08240	COG0588	phosphoglycerate mutase activity
EB816_RS08245	COG2261	transglycosylase associated protein
EB816_RS08280	COG1335	isochorismatase
EB816_RS08290	COG0436	Aminotransferase
EB816_RS08300	COG0561	phosphatase activity
EB816_RS08305	COG0252	asparaginase activity
EB816_RS08320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EB816_RS08330	COG1129	ABC transporter
EB816_RS08345	COG1132	(ABC) transporter
EB816_RS08350	COG4988	ABC transporter
EB816_RS08355	COG1120	ATPase activity
EB816_RS08380	COG1388	LysM domain
EB816_RS08380	COG3942	CHAP domain
EB816_RS08405	COG5433	transposase activity
EB816_RS08410	COG1482	cell wall glycoprotein biosynthetic process
EB816_RS08415	COG1940	carbohydrate kinase activity
EB816_RS08425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB816_RS08425	COG2190	(PTS) system
EB816_RS08425	COG1263	PTS System
EB816_RS08430	COG1621	beta-fructofuranosidase activity
EB816_RS08435	COG1609	Transcriptional regulator
EB816_RS08455	COG2131	deaminase
EB816_RS08460	COG0006	proline dipeptidase activity
EB816_RS08500	COG1194	a g-specific adenine glycosylase
EB816_RS08510	COG3118	belongs to the thioredoxin family
EB816_RS08540	COG0681	Belongs to the peptidase S26 family
EB816_RS08545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EB816_RS08560	COG1882	Formate acetyltransferase
EB816_RS08565	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EB816_RS08580	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EB816_RS08590	COG2814	Major facilitator Superfamily
EB816_RS08595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EB816_RS08620	COG0789	Transcriptional regulator
EB816_RS08640	COG0577	efflux transmembrane transporter activity
EB816_RS08640	COG1136	(ABC) transporter
EB816_RS08655	COG2081	HI0933 family
EB816_RS08665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EB816_RS08670	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EB816_RS08690	COG0456	acetyltransferase
EB816_RS08695	COG1214	PFAM Peptidase M22, glycoprotease
EB816_RS08710	COG0174	glutamine synthetase
EB816_RS08715	COG0789	Transcriptional regulator
EB816_RS08730	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EB816_RS08785	COG0668	transmembrane transport
EB816_RS08795	COG4720	Psort location CytoplasmicMembrane, score
EB816_RS08800	COG0351	phosphomethylpyrimidine kinase
EB816_RS08845	COG1929	Belongs to the glycerate kinase type-1 family
EB816_RS08850	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EB816_RS08880	COG0577	efflux transmembrane transporter activity
EB816_RS08890	COG1136	(ABC) transporter
EB816_RS08895	COG1132	(ABC) transporter
EB816_RS08915	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB816_RS08915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB816_RS08920	COG1447	Phosphotransferase system cellobiose-specific component IIA
EB816_RS08980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EB816_RS08985	COG1476	TRANSCRIPTIONal
EB816_RS09005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EB816_RS09015	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EB816_RS09035	COG1045	serine acetyltransferase
EB816_RS09050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EB816_RS09065	COG3711	transcriptional antiterminator
EB816_RS09090	COG0431	NADPH-dependent FMN reductase
EB816_RS09095	COG1846	Transcriptional regulator
EB816_RS09115	COG4589	Belongs to the CDS family
EB816_RS09125	COG1862	Preprotein translocase
EB816_RS09135	COG1523	belongs to the glycosyl hydrolase 13 family
EB816_RS09150	COG3842	ATPase activity
EB816_RS09190	COG1263	PTS System
EB816_RS09190	COG2190	(PTS) system
EB816_RS09190	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB816_RS09195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EB816_RS09210	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EB816_RS09215	COG0512	Glutamine amidotransferase of anthranilate synthase
EB816_RS09220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EB816_RS09255	COG0601	transmembrane transport
EB816_RS09265	COG1122	ATPase activity
EB816_RS09285	COG0803	Belongs to the bacterial solute-binding protein 9 family
EB816_RS09315	COG3711	transcriptional antiterminator
EB816_RS09330	COG3942	CHAP domain
EB816_RS09330	COG1705	Flagellar rod assembly protein muramidase FlgJ
EB816_RS09335	COG2205	protein histidine kinase activity
EB816_RS09340	COG0745	RESPONSE REGULATOR receiver
EB816_RS09345	COG0577	efflux transmembrane transporter activity
EB816_RS09350	COG1136	(ABC) transporter
EB816_RS09425	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EB816_RS09440	COG1882	Formate acetyltransferase
EB816_RS09445	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB816_RS09450	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EB816_RS09455	COG1447	Phosphotransferase system cellobiose-specific component IIA
EB816_RS09460	COG2390	Transcriptional regulator
EB816_RS09465	COG1349	DNA-binding transcription factor activity
EB816_RS09470	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EB816_RS09490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EB816_RS09505	COG0564	pseudouridine synthase activity
EB816_RS09540	COG0542	response to heat
EB816_RS09545	COG4463	regulation of RNA biosynthetic process
EB816_RS09560	COG0450	alkyl hydroperoxide reductase
EB816_RS09575	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EB816_RS09585	COG3404	Formiminotransferase-cyclodeaminase
EB816_RS09600	COG0531	amino acid
EB816_RS09630	COG3590	peptidase
EB816_RS09635	COG0366	Alpha amylase catalytic
EB816_RS09640	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EB816_RS09640	COG1263	PTS System
EB816_RS09645	COG2188	Transcriptional regulator
EB816_RS09655	COG1733	regulation of RNA biosynthetic process
EB816_RS09660	COG2514	catechol 2,3-dioxygenase activity
EB816_RS09670	COG0602	queuosine metabolic process
EB816_RS09685	COG1328	CTP reductase activity
EB816_RS09710	COG1393	Belongs to the ArsC family
EB816_RS09725	COG0519	Catalyzes the synthesis of GMP from XMP
EB816_RS09770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB816_RS09775	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB816_RS09780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB816_RS09800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EB816_RS09860	COG4974	Belongs to the 'phage' integrase family
EB816_RS09890	COG1511	domain protein
EB816_RS09910	COG0305	Participates in initiation and elongation during chromosome replication
EB816_RS09940	COG1760	l-serine dehydratase
EB816_RS09945	COG1760	l-serine dehydratase
EB816_RS09950	COG0741	lytic transglycosylase activity
EB816_RS09955	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EB816_RS09970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EB816_RS09980	COG0612	Peptidase, M16
EB816_RS09995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EB816_RS10010	COG5433	transposase activity
EB816_RS10035	COG0517	IMP dehydrogenase activity
EB816_RS10035	COG0516	GMP reductase activity
EB816_RS10045	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EB816_RS10050	COG0488	(ABC) transporter
EB816_RS10090	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EB816_RS10095	COG1475	DNA binding