locus-tag	class	description
D8S77_RS00010	COG0592	DNA-directed DNA polymerase activity
D8S77_RS00020	COG0012	GTP binding
D8S77_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D8S77_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D8S77_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D8S77_RS00065	COG0531	amino acid
D8S77_RS00245	COG3942	CHAP domain
D8S77_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D8S77_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D8S77_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D8S77_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D8S77_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D8S77_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D8S77_RS00355	COG1454	alcohol dehydrogenase
D8S77_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
D8S77_RS00360	COG1064	alcohol dehydrogenase
D8S77_RS00365	COG0534	Mate efflux family protein
D8S77_RS00475	COG0201	protein transport
D8S77_RS00620	COG1121	(ABC) transporter
D8S77_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D8S77_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D8S77_RS00665	COG1459	type II secretion system
D8S77_RS00670	COG4537	Required for transformation and DNA binding
D8S77_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D8S77_RS00715	COG1363	Peptidase, m42
D8S77_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D8S77_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D8S77_RS00745	COG1428	Deoxynucleoside kinase
D8S77_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D8S77_RS00810	COG2031	fatty acid transporter
D8S77_RS00820	COG0183	Belongs to the thiolase family
D8S77_RS00825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D8S77_RS00840	COG0251	oxidation-reduction process
D8S77_RS00855	COG1269	ATP hydrolysis coupled proton transport
D8S77_RS00860	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D8S77_RS00870	COG1527	subunit (C
D8S77_RS00875	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
D8S77_RS00910	COG1744	ABC transporter substrate-binding protein PnrA-like
D8S77_RS00955	COG0626	cystathionine gamma-synthase activity
D8S77_RS00985	COG3623	hexulose-6-phosphate isomerase
D8S77_RS01010	COG4175	Glycine betaine
D8S77_RS01010	COG3448	diguanylate cyclase activity
D8S77_RS01020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D8S77_RS01020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D8S77_RS01040	COG3969	phosphoadenosine phosphosulfate
D8S77_RS01045	COG1475	DNA binding
D8S77_RS01065	COG0157	Belongs to the NadC ModD family
D8S77_RS01095	COG1268	BioY protein
D8S77_RS01100	COG1234	tRNA 3'-trailer cleavage
D8S77_RS01135	COG5433	transposase activity
D8S77_RS01145	COG0705	Rhomboid family
D8S77_RS01145	COG0457	Tetratricopeptide repeat
D8S77_RS01165	COG1132	(ABC) transporter
D8S77_RS01170	COG1132	(ABC) transporter
D8S77_RS01180	COG0756	dUTP diphosphatase activity
D8S77_RS01205	COG3290	protein histidine kinase activity
D8S77_RS01230	COG1847	R3H domain protein
D8S77_RS01250	COG1175	transmembrane transport
D8S77_RS01255	COG0395	ABC-type sugar transport system, permease component
D8S77_RS01265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D8S77_RS01280	COG0084	hydrolase, TatD family'
D8S77_RS01305	COG1564	THIamine pyrophosphokinase
D8S77_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D8S77_RS01360	COG0765	amino acid transport
D8S77_RS01380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D8S77_RS01390	COG0719	Fe-S assembly protein
D8S77_RS01395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D8S77_RS01410	COG1686	Belongs to the peptidase S11 family
D8S77_RS01415	COG1686	Belongs to the peptidase S11 family
D8S77_RS01420	COG4166	transmembrane transport
D8S77_RS01425	COG0601	transmembrane transport
D8S77_RS01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D8S77_RS01435	COG0444	Belongs to the ABC transporter superfamily
D8S77_RS01445	COG2801	Transposase and inactivated derivatives
D8S77_RS01490	COG0351	phosphomethylpyrimidine kinase
D8S77_RS01495	COG4720	Psort location CytoplasmicMembrane, score
D8S77_RS01505	COG0668	transmembrane transport
D8S77_RS01560	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
D8S77_RS01575	COG0789	Transcriptional regulator
D8S77_RS01580	COG0174	glutamine synthetase
D8S77_RS01595	COG1214	PFAM Peptidase M22, glycoprotease
D8S77_RS01600	COG0456	acetyltransferase
D8S77_RS01620	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D8S77_RS01625	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D8S77_RS01635	COG2081	HI0933 family
D8S77_RS01670	COG0789	Transcriptional regulator
D8S77_RS01695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D8S77_RS01700	COG2814	Major facilitator Superfamily
D8S77_RS01710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D8S77_RS01725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D8S77_RS01735	COG1882	Formate acetyltransferase
D8S77_RS01750	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D8S77_RS01755	COG0681	Belongs to the peptidase S26 family
D8S77_RS01785	COG3118	belongs to the thioredoxin family
D8S77_RS01795	COG1194	a g-specific adenine glycosylase
D8S77_RS01835	COG0006	proline dipeptidase activity
D8S77_RS01840	COG2131	deaminase
D8S77_RS01860	COG1609	Transcriptional regulator
D8S77_RS01865	COG1621	beta-fructofuranosidase activity
D8S77_RS01870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D8S77_RS01870	COG1263	PTS System
D8S77_RS01870	COG2190	(PTS) system
D8S77_RS01880	COG1940	carbohydrate kinase activity
D8S77_RS01885	COG1482	cell wall glycoprotein biosynthetic process
D8S77_RS01905	COG3942	CHAP domain
D8S77_RS01905	COG1388	LysM domain
D8S77_RS01930	COG1120	ATPase activity
D8S77_RS01935	COG4988	ABC transporter
D8S77_RS01940	COG1132	(ABC) transporter
D8S77_RS01955	COG1129	ABC transporter
D8S77_RS01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D8S77_RS01980	COG0252	asparaginase activity
D8S77_RS01985	COG0561	phosphatase activity
D8S77_RS01995	COG0436	Aminotransferase
D8S77_RS02005	COG1335	isochorismatase
D8S77_RS02040	COG2261	transglycosylase associated protein
D8S77_RS02045	COG0588	phosphoglycerate mutase activity
D8S77_RS02075	COG0484	heat shock protein binding
D8S77_RS02080	COG1024	Enoyl-CoA hydratase
D8S77_RS02105	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D8S77_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
D8S77_RS02115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D8S77_RS02130	COG0439	Biotin carboxylase
D8S77_RS02155	COG3716	PTS system mannose fructose sorbose family IID component
D8S77_RS02160	COG3715	PTS system
D8S77_RS02170	COG0561	phosphatase activity
D8S77_RS02175	COG2252	PERMEase
D8S77_RS02180	COG0802	atpase or kinase
D8S77_RS02190	COG1316	TRANSCRIPTIONal
D8S77_RS02200	COG0537	adenosine 5'-monophosphoramidase activity
D8S77_RS02205	COG1131	(ABC) transporter
D8S77_RS02210	COG4473	ABC transporter
D8S77_RS02235	COG0195	Participates in both transcription termination and antitermination
D8S77_RS02240	COG2740	Nucleic-acid-binding protein implicated in transcription termination
D8S77_RS02270	COG2217	Heavy metal translocating P-type atpase
D8S77_RS02325	COG2860	membrane
D8S77_RS02330	COG0561	phosphatase activity
D8S77_RS02350	COG1283	sodium-dependent phosphate transmembrane transporter activity
D8S77_RS02360	COG0656	L-ascorbic acid biosynthetic process
D8S77_RS02365	COG1755	Isoprenylcysteine carboxyl methyltransferase
D8S77_RS02405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D8S77_RS02410	COG0446	pyridine nucleotide-disulphide oxidoreductase
D8S77_RS02435	COG1131	(ABC) transporter
D8S77_RS02470	COG0768	penicillin binding
D8S77_RS02480	COG0513	Belongs to the DEAD box helicase family
D8S77_RS02490	COG1126	abc transporter atp-binding protein
D8S77_RS02500	COG0492	ferredoxin-NADP+ reductase activity
D8S77_RS02505	COG1113	amino acid transport
D8S77_RS02510	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D8S77_RS02520	COG3579	cysteine-type endopeptidase activity
D8S77_RS02525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D8S77_RS02550	COG0116	Belongs to the methyltransferase superfamily
D8S77_RS02570	COG1028	Short-chain dehydrogenase reductase Sdr
D8S77_RS02580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D8S77_RS02585	COG0183	Belongs to the thiolase family
D8S77_RS02610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D8S77_RS02620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D8S77_RS02620	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D8S77_RS02630	COG0515	serine threonine protein kinase
D8S77_RS02630	COG2815	serine threonine protein kinase
D8S77_RS02640	COG4585	Histidine kinase
D8S77_RS02645	COG2197	response regulator
D8S77_RS02655	COG1098	S1 RNA binding domain
D8S77_RS02665	COG1739	Uncharacterized protein family UPF0029
D8S77_RS02670	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
D8S77_RS02780	COG0383	alpha-mannosidase activity
D8S77_RS02795	COG3525	Glycosyl hydrolase, family 20, catalytic domain
D8S77_RS02800	COG2723	6-phospho-beta-galactosidase activity
D8S77_RS02805	COG1940	carbohydrate kinase activity
D8S77_RS02810	COG1175	transmembrane transport
D8S77_RS02815	COG0395	ABC-type sugar transport system, permease component
D8S77_RS02820	COG1653	transport
D8S77_RS02830	COG2972	Histidine kinase
D8S77_RS02835	COG2207	Transcriptional regulator
D8S77_RS02835	COG4753	response regulator
D8S77_RS02840	COG3250	beta-galactosidase activity
D8S77_RS02850	COG2226	methyltransferase
D8S77_RS02870	COG1605	Chorismate mutase
D8S77_RS02870	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
D8S77_RS02935	COG1518	maintenance of DNA repeat elements
D8S77_RS02940	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
D8S77_RS02945	COG0785	Cytochrome C biogenesis protein
D8S77_RS02950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D8S77_RS02965	COG2972	Histidine kinase
D8S77_RS02990	COG2235	arginine
D8S77_RS03005	COG1288	antiporter activity
D8S77_RS03010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D8S77_RS03015	COG0549	Belongs to the carbamate kinase family
D8S77_RS03025	COG0742	ribosomal rna small subunit methyltransferase
D8S77_RS03035	COG3480	Lon protease (S16) C-terminal proteolytic domain
D8S77_RS03040	COG1609	Transcriptional regulator
D8S77_RS03045	COG4470	Protein conserved in bacteria
D8S77_RS03060	COG0783	Belongs to the Dps family
D8S77_RS03070	COG1940	carbohydrate kinase activity
D8S77_RS03075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D8S77_RS03080	COG1217	gtp-binding protein TYPA
D8S77_RS03115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D8S77_RS03130	COG2302	S4 RNA-binding domain
D8S77_RS03135	COG3599	regulation of cell shape
D8S77_RS03150	COG0494	nUDIX hydrolase
D8S77_RS03155	COG0542	response to heat
D8S77_RS03160	COG4703	Protein of unknown function (DUF1797)
D8S77_RS03165	COG0765	amino acid transport
D8S77_RS03175	COG0415	Belongs to the DNA photolyase family
D8S77_RS03180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D8S77_RS03205	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
D8S77_RS03210	COG1438	arginine binding
D8S77_RS03215	COG0497	DNA recombination
D8S77_RS03230	COG2755	lipolytic protein G-D-S-L family
D8S77_RS03245	COG0582	viral genome integration into host DNA
D8S77_RS03255	COG1396	sequence-specific DNA binding
D8S77_RS03305	COG3723	Recombinational DNA repair protein, rece pathway
D8S77_RS03480	COG4824	toxin secretion phage lysis holin
D8S77_RS03505	COG2217	Heavy metal translocating P-type atpase
D8S77_RS03520	COG1827	regulation of RNA biosynthetic process
D8S77_RS03530	COG2116	formate transmembrane transporter activity
D8S77_RS03535	COG0768	penicillin binding
D8S77_RS03550	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D8S77_RS03570	COG0513	Belongs to the DEAD box helicase family
D8S77_RS03585	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D8S77_RS03590	COG0204	Acyl-transferase
D8S77_RS03595	COG1555	photosystem II stabilization
D8S77_RS03595	COG1596	polysaccharide export
D8S77_RS03600	COG0658	competence protein
D8S77_RS03600	COG2333	competence protein COMEC
D8S77_RS03645	COG1187	pseudouridine synthase activity
D8S77_RS03660	COG2223	nitrite transmembrane transporter activity
D8S77_RS03665	COG4122	O-methyltransferase activity
D8S77_RS03675	COG5433	transposase activity
D8S77_RS03690	COG1476	TRANSCRIPTIONal
D8S77_RS03720	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D8S77_RS03725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D8S77_RS03730	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D8S77_RS03750	COG0726	polysaccharide deacetylase
D8S77_RS03755	COG0513	Belongs to the DEAD box helicase family
D8S77_RS03775	COG1956	GAF domain-containing protein
D8S77_RS03780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D8S77_RS03790	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
D8S77_RS03790	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
D8S77_RS03815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D8S77_RS03820	COG4109	DRTGG domain
D8S77_RS03860	COG1484	DNA-dependent DNA replication
D8S77_RS03970	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D8S77_RS04005	COG2226	methyltransferase
D8S77_RS04015	COG0456	acetyltransferase
D8S77_RS04115	COG0741	lytic transglycosylase activity
D8S77_RS04115	COG0791	NLP P60 protein
D8S77_RS04160	COG3843	relaxase mobilization nuclease domain protein
D8S77_RS04220	COG2814	Major facilitator Superfamily
D8S77_RS04230	COG1187	pseudouridine synthase activity
D8S77_RS04260	COG2723	6-phospho-beta-galactosidase activity
D8S77_RS04270	COG3711	transcriptional antiterminator
D8S77_RS04270	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D8S77_RS04280	COG1447	Phosphotransferase system cellobiose-specific component IIA
D8S77_RS04290	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D8S77_RS04295	COG1126	abc transporter atp-binding protein
D8S77_RS04300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D8S77_RS04320	COG1696	Membrane protein involved in D-alanine export
D8S77_RS04330	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
D8S77_RS04335	COG0657	acetylesterase activity
D8S77_RS04355	COG3833	ABC-type maltose transport systems, permease component
D8S77_RS04360	COG1175	transmembrane transport
D8S77_RS04365	COG2182	Extracellular solute-binding protein
D8S77_RS04370	COG1609	Transcriptional regulator
D8S77_RS04375	COG1640	4-alpha-glucanotransferase
D8S77_RS04380	COG0058	SHG alpha-glucan phosphorylase activity
D8S77_RS04405	COG1131	(ABC) transporter
D8S77_RS04410	COG1725	Transcriptional regulator
D8S77_RS04425	COG0469	pyruvate kinase activity
D8S77_RS04440	COG2824	Alkylphosphonate utilization operon protein PhnA
D8S77_RS04445	COG0765	amino acid transport
D8S77_RS04450	COG1126	abc transporter atp-binding protein
D8S77_RS04455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D8S77_RS04465	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D8S77_RS04470	COG1115	amino acid carrier protein
D8S77_RS04520	COG4591	ABC-type transport system involved in lipoprotein release permease component
D8S77_RS04520	COG1136	(ABC) transporter
D8S77_RS04550	COG0196	riboflavin kinase activity
D8S77_RS04565	COG0483	inositol monophosphate 1-phosphatase activity
D8S77_RS04570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D8S77_RS04570	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
D8S77_RS04580	COG0573	inorganic phosphate transmembrane transporter activity
D8S77_RS04585	COG0581	inorganic phosphate transmembrane transporter activity
D8S77_RS04600	COG0704	Plays a role in the regulation of phosphate uptake
D8S77_RS04615	COG0745	RESPONSE REGULATOR receiver
D8S77_RS04620	COG5002	protein histidine kinase activity
D8S77_RS04635	COG2813	Specifically methylates the guanine in position
D8S77_RS04640	COG0295	cytidine deaminase activity
D8S77_RS04645	COG1744	ABC transporter substrate-binding protein PnrA-like
D8S77_RS04650	COG3845	ABC transporter
D8S77_RS04655	COG4603	Belongs to the binding-protein-dependent transport system permease family
D8S77_RS04660	COG1079	Belongs to the binding-protein-dependent transport system permease family
D8S77_RS04665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D8S77_RS04670	COG4684	Psort location CytoplasmicMembrane, score
D8S77_RS04675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D8S77_RS04695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D8S77_RS04725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D8S77_RS04730	COG1328	CTP reductase activity
D8S77_RS04730	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D8S77_RS04740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D8S77_RS04745	COG0352	thiamine-phosphate diphosphorylase activity
D8S77_RS04745	COG0351	phosphomethylpyrimidine kinase
D8S77_RS04755	COG0488	(ABC) transporter
D8S77_RS04775	COG2188	Transcriptional regulator
D8S77_RS04785	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D8S77_RS04805	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
D8S77_RS04835	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
D8S77_RS04840	COG0511	ligase activity, forming carbon-carbon bonds
D8S77_RS04850	COG2851	Citrate transporter
D8S77_RS04865	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
D8S77_RS04870	COG0511	ligase activity, forming carbon-carbon bonds
D8S77_RS04920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D8S77_RS04925	COG0758	DNA mediated transformation
D8S77_RS04945	COG1272	protein, Hemolysin III
D8S77_RS04965	COG0346	lactoylglutathione lyase activity
D8S77_RS04970	COG3764	Sortase (surface protein transpeptidase)
D8S77_RS04990	COG1132	(ABC) transporter
D8S77_RS04995	COG1132	(ABC) transporter
D8S77_RS05025	COG2890	protein-(glutamine-N5) methyltransferase activity
D8S77_RS05050	COG2233	PERMEase
D8S77_RS05070	COG1174	glycine betaine transport
D8S77_RS05085	COG4221	oxidoreductase activity
D8S77_RS05090	COG0280	phosphate acetyltransferase
D8S77_RS05095	COG0564	pseudouridine synthase activity
D8S77_RS05105	COG2357	RelA SpoT domain protein
D8S77_RS05120	COG1104	cysteine desulfurase activity
D8S77_RS05135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D8S77_RS05145	COG0628	permease
D8S77_RS05155	COG0038	chloride channel
D8S77_RS05160	COG3700	Belongs to the class B bacterial acid phosphatase family
D8S77_RS05175	COG3493	citrate carrier protein
D8S77_RS05180	COG3290	protein histidine kinase activity
D8S77_RS05185	COG4565	transcriptional regulatory protein
D8S77_RS05195	COG1177	transmembrane transport
D8S77_RS05200	COG1176	ABC-type spermidine putrescine transport system, permease component I
D8S77_RS05215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D8S77_RS05235	COG0285	dihydrofolate synthase activity
D8S77_RS05265	COG1396	sequence-specific DNA binding
D8S77_RS05280	COG1131	(ABC) transporter
D8S77_RS05345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D8S77_RS05360	COG1012	belongs to the aldehyde dehydrogenase family
D8S77_RS05370	COG4753	response regulator
D8S77_RS05370	COG2207	Transcriptional regulator
D8S77_RS05375	COG2972	Histidine kinase
D8S77_RS05380	COG3716	PTS system mannose fructose sorbose family IID component
D8S77_RS05385	COG3715	PTS system
D8S77_RS05420	COG0105	UTP biosynthetic process
D8S77_RS05435	COG0647	UMP catabolic process
D8S77_RS05445	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D8S77_RS05465	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
D8S77_RS05470	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D8S77_RS05475	COG3442	glutamine amidotransferase
D8S77_RS05480	COG0095	Lipoate-protein ligase
D8S77_RS05485	COG5492	domain, Protein
D8S77_RS05505	COG0508	dehydrogenase complex catalyzes the overall conversion of
D8S77_RS05510	COG0022	dehydrogenase e1 component
D8S77_RS05510	COG0508	dehydrogenase complex catalyzes the overall conversion of
D8S77_RS05515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D8S77_RS05520	COG0488	(ABC) transporter
D8S77_RS05540	COG1129	ABC transporter
D8S77_RS05560	COG1293	RNA-binding protein homologous to eukaryotic snRNP
D8S77_RS05565	COG0457	Tetratricopeptide repeat
D8S77_RS05570	COG0628	permease
D8S77_RS05575	COG1051	belongs to the nudix hydrolase family
D8S77_RS05580	COG1088	dTDP-glucose 4,6-dehydratase activity
D8S77_RS05590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
D8S77_RS05595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D8S77_RS05605	COG2384	SAM-dependent methyltransferase
D8S77_RS05610	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D8S77_RS05625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
D8S77_RS05625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D8S77_RS05630	COG0300	oxidoreductase activity
D8S77_RS05640	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
D8S77_RS05645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D8S77_RS05690	COG0539	negative regulation of cytoplasmic translation
D8S77_RS05710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D8S77_RS05720	COG0187	DNA topoisomerase II activity
D8S77_RS05740	COG0765	amino acid transport
D8S77_RS05745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D8S77_RS05770	COG0583	DNA-binding transcription factor activity
D8S77_RS05785	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D8S77_RS05830	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D8S77_RS05840	COG3425	synthase
D8S77_RS05875	COG0745	RESPONSE REGULATOR receiver
D8S77_RS05880	COG2357	RelA SpoT domain protein
D8S77_RS05885	COG0737	Belongs to the 5'-nucleotidase family
D8S77_RS05890	COG0242	peptide deformylase activity
D8S77_RS05900	COG0488	(ABC) transporter
D8S77_RS05920	COG0105	UTP biosynthetic process
D8S77_RS05945	COG1705	Flagellar rod assembly protein muramidase FlgJ
D8S77_RS05945	COG1388	LysM domain
D8S77_RS05950	COG1388	LysM domain
D8S77_RS05950	COG1705	Flagellar rod assembly protein muramidase FlgJ
D8S77_RS05955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D8S77_RS05955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D8S77_RS05955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D8S77_RS05960	COG1105	Belongs to the carbohydrate kinase PfkB family
D8S77_RS05965	COG1349	DNA-binding transcription factor activity
D8S77_RS06015	COG1837	Belongs to the UPF0109 family
D8S77_RS06025	COG0584	glycerophosphoryl diester phosphodiesterase
D8S77_RS06030	COG0577	efflux transmembrane transporter activity
D8S77_RS06035	COG1136	(ABC) transporter
D8S77_RS06040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D8S77_RS06080	COG5433	transposase activity
D8S77_RS06085	COG0564	pseudouridine synthase activity
D8S77_RS06095	COG0583	DNA-binding transcription factor activity
D8S77_RS06105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
D8S77_RS06130	COG1104	cysteine desulfurase activity
D8S77_RS06140	COG0285	dihydrofolate synthase activity
D8S77_RS06145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D8S77_RS06165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D8S77_RS06170	COG1368	sulfuric ester hydrolase activity
D8S77_RS06230	COG1216	Glycosyl transferase, family 2
D8S77_RS06275	COG2151	metal-sulfur cluster biosynthetic enzyme
D8S77_RS06280	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D8S77_RS06285	COG0358	DNA primase activity
D8S77_RS06290	COG1970	mechanosensitive ion channel activity
D8S77_RS06315	COG2321	neutral zinc metallopeptidase
D8S77_RS06325	COG0577	efflux transmembrane transporter activity
D8S77_RS06410	COG1597	lipid kinase activity
D8S77_RS06420	COG4708	membrane
D8S77_RS06430	COG5433	transposase activity
D8S77_RS06455	COG1131	(ABC) transporter
D8S77_RS06550	COG0038	chloride channel
D8S77_RS06560	COG0716	FMN binding
D8S77_RS06565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
D8S77_RS06575	COG2222	sugar isomerase
D8S77_RS06580	COG2188	Transcriptional regulator
D8S77_RS06615	COG0436	Aminotransferase
D8S77_RS06620	COG1199	ATP-dependent helicase activity
D8S77_RS06620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D8S77_RS06635	COG2177	Part of the ABC transporter FtsEX involved in
D8S77_RS06640	COG2884	Cell division ATP-binding protein ftsE
D8S77_RS06650	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D8S77_RS06660	COG0800	Aldolase
D8S77_RS06675	COG1028	Short-chain dehydrogenase reductase Sdr
D8S77_RS06690	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D8S77_RS06695	COG3715	PTS system
D8S77_RS06700	COG3716	PTS system mannose fructose sorbose family IID component
D8S77_RS06710	COG1609	Transcriptional regulator
D8S77_RS06725	COG1078	dGTPase activity
D8S77_RS06760	COG0772	Belongs to the SEDS family
D8S77_RS06770	COG1164	Oligoendopeptidase f
D8S77_RS06775	COG0386	Belongs to the glutathione peroxidase family
D8S77_RS06795	COG5433	transposase activity
D8S77_RS06830	COG4443	Transcriptional Coactivator p15 (PC4)
D8S77_RS06835	COG0826	peptidase U32
D8S77_RS06880	COG2183	response to ionizing radiation
D8S77_RS06890	COG0701	Predicted permease
D8S77_RS06895	COG3689	TIGRFAM TIGR03943 family protein
D8S77_RS06905	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D8S77_RS06905	COG1263	PTS System
D8S77_RS06905	COG2190	(PTS) system
D8S77_RS06910	COG3711	transcriptional antiterminator
D8S77_RS06915	COG0477	Major facilitator Superfamily
D8S77_RS06920	COG0552	protein localization to endoplasmic reticulum
D8S77_RS06925	COG0561	phosphatase activity
D8S77_RS06930	COG0561	phosphatase activity
D8S77_RS06940	COG0124	histidyl-tRNA synthetase
D8S77_RS07060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D8S77_RS07070	COG1196	nuclear chromosome segregation
D8S77_RS07080	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
D8S77_RS07085	COG5002	protein histidine kinase activity
D8S77_RS07090	COG0745	RESPONSE REGULATOR receiver
D8S77_RS07105	COG0183	Belongs to the thiolase family
D8S77_RS07125	COG4555	ABC transporter
D8S77_RS07135	COG0438	transferase activity, transferring glycosyl groups
D8S77_RS07145	COG1609	Transcriptional regulator
D8S77_RS07150	COG0006	proline dipeptidase activity
D8S77_RS07155	COG0778	Nitroreductase
D8S77_RS07165	COG0463	Glycosyl transferase, family 2
D8S77_RS07195	COG0557	exoribonuclease II activity
D8S77_RS07215	COG0433	COG0433 Predicted ATPase
D8S77_RS07305	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D8S77_RS07315	COG1573	uracil-dna glycosylase
D8S77_RS07320	COG1702	phosphate starvation-inducible protein PhoH
D8S77_RS07410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D8S77_RS07420	COG0494	nUDIX hydrolase
D8S77_RS07435	COG0673	inositol 2-dehydrogenase activity
D8S77_RS07440	COG1028	Short-chain dehydrogenase reductase Sdr
D8S77_RS07560	COG1304	FMN binding
D8S77_RS07570	COG0708	Exodeoxyribonuclease III
D8S77_RS07575	COG1393	Belongs to the ArsC family
D8S77_RS07605	COG0470	DNA polymerase III
D8S77_RS07635	COG2244	polysaccharide biosynthetic process
D8S77_RS07645	COG1120	ATPase activity
D8S77_RS07650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D8S77_RS07655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D8S77_RS07660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D8S77_RS07675	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D8S77_RS07680	COG1253	flavin adenine dinucleotide binding
D8S77_RS07685	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
D8S77_RS07690	COG1242	4 iron, 4 sulfur cluster binding
D8S77_RS07695	COG0671	phosphoesterase, PA-phosphatase related
D8S77_RS07700	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
D8S77_RS07715	COG1187	pseudouridine synthase activity
D8S77_RS07770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D8S77_RS07775	COG1254	Belongs to the acylphosphatase family
D8S77_RS07790	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D8S77_RS07810	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D8S77_RS07820	COG1484	DNA-dependent DNA replication
D8S77_RS07835	COG5433	transposase activity
D8S77_RS07845	COG0745	RESPONSE REGULATOR receiver
D8S77_RS07860	COG1704	LemA family
D8S77_RS07870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D8S77_RS07875	COG0569	domain protein
D8S77_RS07885	COG1114	Component of the transport system for branched-chain amino acids
D8S77_RS07900	COG1464	Belongs to the NlpA lipoprotein family
D8S77_RS07905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D8S77_RS07925	COG2226	methyltransferase
D8S77_RS07930	COG0799	negative regulation of ribosome biogenesis
D8S77_RS07935	COG1713	HD superfamily hydrolase involved in NAD metabolism
D8S77_RS07945	COG1534	Rna-binding protein
D8S77_RS07950	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D8S77_RS07955	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
D8S77_RS07995	COG1929	Belongs to the glycerate kinase type-1 family
D8S77_RS08000	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
D8S77_RS08030	COG0577	efflux transmembrane transporter activity
D8S77_RS08035	COG1136	(ABC) transporter
D8S77_RS08060	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D8S77_RS08060	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D8S77_RS08065	COG1447	Phosphotransferase system cellobiose-specific component IIA
D8S77_RS08110	COG4974	Belongs to the 'phage' integrase family
D8S77_RS08120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D8S77_RS08125	COG1476	TRANSCRIPTIONal
D8S77_RS08145	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D8S77_RS08155	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
D8S77_RS08175	COG1045	serine acetyltransferase
D8S77_RS08190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D8S77_RS08195	COG3037	sugar-specific permease SgaT UlaA
D8S77_RS08205	COG3711	transcriptional antiterminator
D8S77_RS08235	COG1846	Transcriptional regulator
D8S77_RS08255	COG4589	Belongs to the CDS family
D8S77_RS08265	COG1862	Preprotein translocase
D8S77_RS08275	COG1523	belongs to the glycosyl hydrolase 13 family
D8S77_RS08290	COG3842	ATPase activity
D8S77_RS08330	COG2190	(PTS) system
D8S77_RS08330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D8S77_RS08330	COG1263	PTS System
D8S77_RS08335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D8S77_RS08350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D8S77_RS08355	COG0512	Glutamine amidotransferase of anthranilate synthase
D8S77_RS08360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D8S77_RS08395	COG0601	transmembrane transport
D8S77_RS08425	COG0803	Belongs to the bacterial solute-binding protein 9 family
D8S77_RS08455	COG3711	transcriptional antiterminator
D8S77_RS08470	COG1705	Flagellar rod assembly protein muramidase FlgJ
D8S77_RS08470	COG3942	CHAP domain
D8S77_RS08475	COG2205	protein histidine kinase activity
D8S77_RS08480	COG0745	RESPONSE REGULATOR receiver
D8S77_RS08485	COG0577	efflux transmembrane transporter activity
D8S77_RS08490	COG1136	(ABC) transporter
D8S77_RS08565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D8S77_RS08580	COG1882	Formate acetyltransferase
D8S77_RS08585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D8S77_RS08590	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D8S77_RS08595	COG1447	Phosphotransferase system cellobiose-specific component IIA
D8S77_RS08600	COG2390	Transcriptional regulator
D8S77_RS08605	COG1349	DNA-binding transcription factor activity
D8S77_RS08610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D8S77_RS08630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D8S77_RS08645	COG0564	pseudouridine synthase activity
D8S77_RS08680	COG0542	response to heat
D8S77_RS08685	COG4463	regulation of RNA biosynthetic process
D8S77_RS08700	COG0450	alkyl hydroperoxide reductase
D8S77_RS08715	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D8S77_RS08725	COG3404	Formiminotransferase-cyclodeaminase
D8S77_RS08740	COG0531	amino acid
D8S77_RS08770	COG3590	peptidase
D8S77_RS08775	COG0366	Alpha amylase catalytic
D8S77_RS08780	COG1263	PTS System
D8S77_RS08780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D8S77_RS08785	COG2188	Transcriptional regulator
D8S77_RS08795	COG1733	regulation of RNA biosynthetic process
D8S77_RS08810	COG0602	queuosine metabolic process
D8S77_RS08825	COG1328	CTP reductase activity
D8S77_RS08850	COG1393	Belongs to the ArsC family
D8S77_RS08865	COG0519	Catalyzes the synthesis of GMP from XMP
D8S77_RS08875	COG2814	Major facilitator Superfamily
D8S77_RS08910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D8S77_RS08915	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D8S77_RS08920	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D8S77_RS08995	COG4974	Belongs to the 'phage' integrase family
D8S77_RS09025	COG1511	domain protein
D8S77_RS09045	COG0305	Participates in initiation and elongation during chromosome replication
D8S77_RS09075	COG1760	l-serine dehydratase
D8S77_RS09080	COG1760	l-serine dehydratase
D8S77_RS09085	COG0741	lytic transglycosylase activity
D8S77_RS09090	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
D8S77_RS09105	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D8S77_RS09115	COG0612	Peptidase, M16
D8S77_RS09125	COG1215	transferase activity, transferring glycosyl groups
D8S77_RS09140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D8S77_RS09160	COG0517	IMP dehydrogenase activity
D8S77_RS09160	COG0516	GMP reductase activity
D8S77_RS09170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D8S77_RS09175	COG0488	(ABC) transporter
D8S77_RS09215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D8S77_RS09220	COG1475	DNA binding