locus-tag	class	description
ETT53_RS00010	COG0592	DNA-directed DNA polymerase activity
ETT53_RS00020	COG0012	GTP binding
ETT53_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETT53_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETT53_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETT53_RS00065	COG0531	amino acid
ETT53_RS00245	COG3942	CHAP domain
ETT53_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETT53_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETT53_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETT53_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETT53_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETT53_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETT53_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
ETT53_RS00355	COG1454	alcohol dehydrogenase
ETT53_RS00360	COG1064	alcohol dehydrogenase
ETT53_RS00365	COG0534	Mate efflux family protein
ETT53_RS00475	COG0201	protein transport
ETT53_RS00620	COG1121	(ABC) transporter
ETT53_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETT53_RS00635	COG0582	viral genome integration into host DNA
ETT53_RS00770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT53_RS00790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETT53_RS00795	COG1459	type II secretion system
ETT53_RS00800	COG4537	Required for transformation and DNA binding
ETT53_RS00840	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETT53_RS00845	COG1363	Peptidase, m42
ETT53_RS00860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT53_RS00865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETT53_RS00875	COG1428	Deoxynucleoside kinase
ETT53_RS00880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETT53_RS00930	COG2031	fatty acid transporter
ETT53_RS00945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETT53_RS00960	COG0251	oxidation-reduction process
ETT53_RS00975	COG1269	ATP hydrolysis coupled proton transport
ETT53_RS00980	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETT53_RS00990	COG1527	subunit (C
ETT53_RS00995	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
ETT53_RS01030	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT53_RS01080	COG0626	cystathionine gamma-synthase activity
ETT53_RS01110	COG3623	hexulose-6-phosphate isomerase
ETT53_RS01135	COG3448	diguanylate cyclase activity
ETT53_RS01135	COG4175	Glycine betaine
ETT53_RS01145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT53_RS01145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT53_RS01165	COG3969	phosphoadenosine phosphosulfate
ETT53_RS01170	COG1475	DNA binding
ETT53_RS01190	COG0157	Belongs to the NadC ModD family
ETT53_RS01220	COG1268	BioY protein
ETT53_RS01225	COG1234	tRNA 3'-trailer cleavage
ETT53_RS01260	COG0457	Tetratricopeptide repeat
ETT53_RS01260	COG0705	Rhomboid family
ETT53_RS01280	COG1132	(ABC) transporter
ETT53_RS01285	COG1132	(ABC) transporter
ETT53_RS01295	COG0756	dUTP diphosphatase activity
ETT53_RS01320	COG3290	protein histidine kinase activity
ETT53_RS01345	COG1847	R3H domain protein
ETT53_RS01365	COG1175	transmembrane transport
ETT53_RS01370	COG0395	ABC-type sugar transport system, permease component
ETT53_RS01380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETT53_RS01395	COG0084	hydrolase, TatD family'
ETT53_RS01420	COG1564	THIamine pyrophosphokinase
ETT53_RS01435	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETT53_RS01475	COG0765	amino acid transport
ETT53_RS01495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETT53_RS01505	COG0719	Fe-S assembly protein
ETT53_RS01510	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETT53_RS01525	COG1686	Belongs to the peptidase S11 family
ETT53_RS01530	COG1686	Belongs to the peptidase S11 family
ETT53_RS01535	COG4166	transmembrane transport
ETT53_RS01540	COG0601	transmembrane transport
ETT53_RS01545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETT53_RS01550	COG0444	Belongs to the ABC transporter superfamily
ETT53_RS01610	COG0351	phosphomethylpyrimidine kinase
ETT53_RS01615	COG4720	Psort location CytoplasmicMembrane, score
ETT53_RS01625	COG0668	transmembrane transport
ETT53_RS01680	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ETT53_RS01695	COG0789	Transcriptional regulator
ETT53_RS01700	COG0174	glutamine synthetase
ETT53_RS01715	COG1214	PFAM Peptidase M22, glycoprotease
ETT53_RS01720	COG0456	acetyltransferase
ETT53_RS01740	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ETT53_RS01745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETT53_RS01755	COG2081	HI0933 family
ETT53_RS01790	COG0789	Transcriptional regulator
ETT53_RS01815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETT53_RS01820	COG2814	Major facilitator Superfamily
ETT53_RS01830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT53_RS01845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETT53_RS01850	COG1882	Formate acetyltransferase
ETT53_RS01865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETT53_RS01870	COG0681	Belongs to the peptidase S26 family
ETT53_RS01900	COG3118	belongs to the thioredoxin family
ETT53_RS01910	COG1194	a g-specific adenine glycosylase
ETT53_RS01950	COG0006	proline dipeptidase activity
ETT53_RS01955	COG2131	deaminase
ETT53_RS01975	COG1609	Transcriptional regulator
ETT53_RS01980	COG1621	beta-fructofuranosidase activity
ETT53_RS01985	COG1263	PTS System
ETT53_RS01985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT53_RS01985	COG2190	(PTS) system
ETT53_RS01995	COG1940	carbohydrate kinase activity
ETT53_RS02000	COG1482	cell wall glycoprotein biosynthetic process
ETT53_RS02005	COG5433	transposase activity
ETT53_RS02030	COG3942	CHAP domain
ETT53_RS02030	COG1388	LysM domain
ETT53_RS02055	COG1120	ATPase activity
ETT53_RS02060	COG4988	ABC transporter
ETT53_RS02065	COG1132	(ABC) transporter
ETT53_RS02080	COG1129	ABC transporter
ETT53_RS02090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETT53_RS02105	COG0252	asparaginase activity
ETT53_RS02110	COG0561	phosphatase activity
ETT53_RS02120	COG0436	Aminotransferase
ETT53_RS02130	COG1335	isochorismatase
ETT53_RS02165	COG2261	transglycosylase associated protein
ETT53_RS02170	COG0588	phosphoglycerate mutase activity
ETT53_RS02205	COG1024	Enoyl-CoA hydratase
ETT53_RS02230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETT53_RS02235	COG1028	Short-chain dehydrogenase reductase Sdr
ETT53_RS02240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETT53_RS02255	COG0439	Biotin carboxylase
ETT53_RS02280	COG3716	PTS system mannose fructose sorbose family IID component
ETT53_RS02285	COG3715	PTS system
ETT53_RS02295	COG0561	phosphatase activity
ETT53_RS02300	COG2252	PERMEase
ETT53_RS02305	COG0802	atpase or kinase
ETT53_RS02315	COG1316	TRANSCRIPTIONal
ETT53_RS02325	COG0537	adenosine 5'-monophosphoramidase activity
ETT53_RS02330	COG1131	(ABC) transporter
ETT53_RS02335	COG4473	ABC transporter
ETT53_RS02360	COG0195	Participates in both transcription termination and antitermination
ETT53_RS02365	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETT53_RS02395	COG2217	Heavy metal translocating P-type atpase
ETT53_RS02455	COG2860	membrane
ETT53_RS02460	COG0561	phosphatase activity
ETT53_RS02480	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETT53_RS02490	COG0656	L-ascorbic acid biosynthetic process
ETT53_RS02495	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETT53_RS02535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT53_RS02540	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETT53_RS02565	COG1131	(ABC) transporter
ETT53_RS02605	COG0768	penicillin binding
ETT53_RS02615	COG0513	Belongs to the DEAD box helicase family
ETT53_RS02625	COG1126	abc transporter atp-binding protein
ETT53_RS02635	COG0492	ferredoxin-NADP+ reductase activity
ETT53_RS02640	COG1113	amino acid transport
ETT53_RS02645	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETT53_RS02655	COG3579	cysteine-type endopeptidase activity
ETT53_RS02660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT53_RS02685	COG0116	Belongs to the methyltransferase superfamily
ETT53_RS02700	COG2610	gluconate transmembrane transporter activity
ETT53_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
ETT53_RS02715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETT53_RS02720	COG0183	Belongs to the thiolase family
ETT53_RS02725	COG0583	DNA-binding transcription factor activity
ETT53_RS02745	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETT53_RS02755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT53_RS02755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETT53_RS02765	COG0515	serine threonine protein kinase
ETT53_RS02765	COG2815	serine threonine protein kinase
ETT53_RS02775	COG4585	Histidine kinase
ETT53_RS02780	COG2197	response regulator
ETT53_RS02790	COG1098	S1 RNA binding domain
ETT53_RS02800	COG1739	Uncharacterized protein family UPF0029
ETT53_RS02805	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETT53_RS02910	COG0383	alpha-mannosidase activity
ETT53_RS02920	COG1609	Transcriptional regulator
ETT53_RS02925	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ETT53_RS02930	COG2723	6-phospho-beta-galactosidase activity
ETT53_RS02935	COG1940	carbohydrate kinase activity
ETT53_RS02940	COG1175	transmembrane transport
ETT53_RS02945	COG0395	ABC-type sugar transport system, permease component
ETT53_RS02950	COG1653	transport
ETT53_RS02960	COG2972	Histidine kinase
ETT53_RS02965	COG2207	Transcriptional regulator
ETT53_RS02965	COG4753	response regulator
ETT53_RS02970	COG3250	beta-galactosidase activity
ETT53_RS02980	COG2226	methyltransferase
ETT53_RS03000	COG1605	Chorismate mutase
ETT53_RS03000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETT53_RS03010	COG5433	transposase activity
ETT53_RS03060	COG0673	inositol 2-dehydrogenase activity
ETT53_RS03070	COG0785	Cytochrome C biogenesis protein
ETT53_RS03075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT53_RS03090	COG2972	Histidine kinase
ETT53_RS03115	COG2235	arginine
ETT53_RS03120	COG0454	-acetyltransferase
ETT53_RS03130	COG1288	antiporter activity
ETT53_RS03135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT53_RS03140	COG0549	Belongs to the carbamate kinase family
ETT53_RS03150	COG0742	ribosomal rna small subunit methyltransferase
ETT53_RS03160	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETT53_RS03165	COG1609	Transcriptional regulator
ETT53_RS03170	COG4470	Protein conserved in bacteria
ETT53_RS03185	COG0783	Belongs to the Dps family
ETT53_RS03195	COG1940	carbohydrate kinase activity
ETT53_RS03200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETT53_RS03205	COG1217	gtp-binding protein TYPA
ETT53_RS03240	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETT53_RS03255	COG2302	S4 RNA-binding domain
ETT53_RS03260	COG3599	regulation of cell shape
ETT53_RS03275	COG0494	nUDIX hydrolase
ETT53_RS03280	COG0542	response to heat
ETT53_RS03285	COG4703	Protein of unknown function (DUF1797)
ETT53_RS03290	COG0765	amino acid transport
ETT53_RS03300	COG0415	Belongs to the DNA photolyase family
ETT53_RS03305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT53_RS03330	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETT53_RS03335	COG1438	arginine binding
ETT53_RS03340	COG0497	DNA recombination
ETT53_RS03355	COG2755	lipolytic protein G-D-S-L family
ETT53_RS03370	COG2217	Heavy metal translocating P-type atpase
ETT53_RS03385	COG1827	regulation of RNA biosynthetic process
ETT53_RS03395	COG2116	formate transmembrane transporter activity
ETT53_RS03415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT53_RS03435	COG0513	Belongs to the DEAD box helicase family
ETT53_RS03450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETT53_RS03455	COG0204	Acyl-transferase
ETT53_RS03460	COG1555	photosystem II stabilization
ETT53_RS03460	COG1596	polysaccharide export
ETT53_RS03465	COG0658	competence protein
ETT53_RS03465	COG2333	competence protein COMEC
ETT53_RS03510	COG1187	pseudouridine synthase activity
ETT53_RS03525	COG2223	nitrite transmembrane transporter activity
ETT53_RS03530	COG4122	O-methyltransferase activity
ETT53_RS03545	COG1476	TRANSCRIPTIONal
ETT53_RS03570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETT53_RS03575	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETT53_RS03580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETT53_RS03600	COG0726	polysaccharide deacetylase
ETT53_RS03605	COG0513	Belongs to the DEAD box helicase family
ETT53_RS03625	COG1956	GAF domain-containing protein
ETT53_RS03630	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETT53_RS03640	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETT53_RS03640	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETT53_RS03665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETT53_RS03670	COG4109	DRTGG domain
ETT53_RS03720	COG2814	Major facilitator Superfamily
ETT53_RS03730	COG1187	pseudouridine synthase activity
ETT53_RS03760	COG2723	6-phospho-beta-galactosidase activity
ETT53_RS03770	COG3711	transcriptional antiterminator
ETT53_RS03770	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETT53_RS03780	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT53_RS03790	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT53_RS03795	COG1126	abc transporter atp-binding protein
ETT53_RS03800	COG0765	amino acid transport
ETT53_RS03820	COG1696	Membrane protein involved in D-alanine export
ETT53_RS03830	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETT53_RS03835	COG0657	acetylesterase activity
ETT53_RS03855	COG3833	ABC-type maltose transport systems, permease component
ETT53_RS03860	COG1175	transmembrane transport
ETT53_RS03865	COG2182	Extracellular solute-binding protein
ETT53_RS03870	COG1609	Transcriptional regulator
ETT53_RS03875	COG1640	4-alpha-glucanotransferase
ETT53_RS03880	COG0058	SHG alpha-glucan phosphorylase activity
ETT53_RS03905	COG1131	(ABC) transporter
ETT53_RS03910	COG1725	Transcriptional regulator
ETT53_RS03925	COG0469	pyruvate kinase activity
ETT53_RS03940	COG2824	Alkylphosphonate utilization operon protein PhnA
ETT53_RS03945	COG0765	amino acid transport
ETT53_RS03950	COG1126	abc transporter atp-binding protein
ETT53_RS03955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT53_RS03965	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETT53_RS03970	COG1115	amino acid carrier protein
ETT53_RS04020	COG1136	(ABC) transporter
ETT53_RS04020	COG4591	ABC-type transport system involved in lipoprotein release permease component
ETT53_RS04050	COG0196	riboflavin kinase activity
ETT53_RS04065	COG0483	inositol monophosphate 1-phosphatase activity
ETT53_RS04070	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT53_RS04070	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ETT53_RS04080	COG0573	inorganic phosphate transmembrane transporter activity
ETT53_RS04085	COG0581	inorganic phosphate transmembrane transporter activity
ETT53_RS04100	COG0704	Plays a role in the regulation of phosphate uptake
ETT53_RS04115	COG0745	RESPONSE REGULATOR receiver
ETT53_RS04120	COG5002	protein histidine kinase activity
ETT53_RS04135	COG2813	Specifically methylates the guanine in position
ETT53_RS04140	COG0295	cytidine deaminase activity
ETT53_RS04145	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT53_RS04150	COG3845	ABC transporter
ETT53_RS04155	COG4603	Belongs to the binding-protein-dependent transport system permease family
ETT53_RS04160	COG1079	Belongs to the binding-protein-dependent transport system permease family
ETT53_RS04165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT53_RS04170	COG4684	Psort location CytoplasmicMembrane, score
ETT53_RS04175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETT53_RS04185	COG0095	Lipoate-protein ligase
ETT53_RS04195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETT53_RS04225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETT53_RS04230	COG1328	CTP reductase activity
ETT53_RS04230	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETT53_RS04235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETT53_RS04240	COG0352	thiamine-phosphate diphosphorylase activity
ETT53_RS04240	COG0351	phosphomethylpyrimidine kinase
ETT53_RS04250	COG0488	(ABC) transporter
ETT53_RS04270	COG2188	Transcriptional regulator
ETT53_RS04280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETT53_RS04300	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ETT53_RS04330	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT53_RS04335	COG0511	ligase activity, forming carbon-carbon bonds
ETT53_RS04345	COG2851	Citrate transporter
ETT53_RS04360	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT53_RS04365	COG0511	ligase activity, forming carbon-carbon bonds
ETT53_RS04415	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETT53_RS04420	COG0758	DNA mediated transformation
ETT53_RS04440	COG1272	protein, Hemolysin III
ETT53_RS04460	COG0346	lactoylglutathione lyase activity
ETT53_RS04465	COG3764	Sortase (surface protein transpeptidase)
ETT53_RS04485	COG1132	(ABC) transporter
ETT53_RS04490	COG1132	(ABC) transporter
ETT53_RS04520	COG2890	protein-(glutamine-N5) methyltransferase activity
ETT53_RS04545	COG2233	PERMEase
ETT53_RS04565	COG1174	glycine betaine transport
ETT53_RS04580	COG4221	oxidoreductase activity
ETT53_RS04585	COG0280	phosphate acetyltransferase
ETT53_RS04590	COG0564	pseudouridine synthase activity
ETT53_RS04600	COG2357	RelA SpoT domain protein
ETT53_RS04615	COG1104	cysteine desulfurase activity
ETT53_RS04630	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ETT53_RS04640	COG0628	permease
ETT53_RS04650	COG0038	chloride channel
ETT53_RS04655	COG3700	Belongs to the class B bacterial acid phosphatase family
ETT53_RS04670	COG3493	citrate carrier protein
ETT53_RS04675	COG3290	protein histidine kinase activity
ETT53_RS04680	COG4565	transcriptional regulatory protein
ETT53_RS04690	COG1177	transmembrane transport
ETT53_RS04695	COG1176	ABC-type spermidine putrescine transport system, permease component I
ETT53_RS04710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETT53_RS04730	COG0285	dihydrofolate synthase activity
ETT53_RS04760	COG1396	sequence-specific DNA binding
ETT53_RS04775	COG1131	(ABC) transporter
ETT53_RS04850	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT53_RS04865	COG1012	belongs to the aldehyde dehydrogenase family
ETT53_RS04875	COG2207	Transcriptional regulator
ETT53_RS04875	COG4753	response regulator
ETT53_RS04880	COG2972	Histidine kinase
ETT53_RS04885	COG3716	PTS system mannose fructose sorbose family IID component
ETT53_RS04890	COG3715	PTS system
ETT53_RS04935	COG5433	transposase activity
ETT53_RS04940	COG0105	UTP biosynthetic process
ETT53_RS04955	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ETT53_RS04980	COG0647	UMP catabolic process
ETT53_RS04990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETT53_RS05010	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETT53_RS05015	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT53_RS05020	COG3442	glutamine amidotransferase
ETT53_RS05025	COG0095	Lipoate-protein ligase
ETT53_RS05030	COG5492	domain, Protein
ETT53_RS05050	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT53_RS05055	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT53_RS05055	COG0022	dehydrogenase e1 component
ETT53_RS05060	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETT53_RS05065	COG0488	(ABC) transporter
ETT53_RS05085	COG1129	ABC transporter
ETT53_RS05105	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ETT53_RS05110	COG0457	Tetratricopeptide repeat
ETT53_RS05115	COG0628	permease
ETT53_RS05120	COG1051	belongs to the nudix hydrolase family
ETT53_RS05125	COG1088	dTDP-glucose 4,6-dehydratase activity
ETT53_RS05135	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETT53_RS05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETT53_RS05150	COG2384	SAM-dependent methyltransferase
ETT53_RS05155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETT53_RS05170	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETT53_RS05170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETT53_RS05175	COG0300	oxidoreductase activity
ETT53_RS05185	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETT53_RS05190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETT53_RS05235	COG0539	negative regulation of cytoplasmic translation
ETT53_RS05255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETT53_RS05265	COG0187	DNA topoisomerase II activity
ETT53_RS05285	COG0765	amino acid transport
ETT53_RS05290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT53_RS05315	COG0583	DNA-binding transcription factor activity
ETT53_RS05375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETT53_RS05390	COG3425	synthase
ETT53_RS05425	COG0745	RESPONSE REGULATOR receiver
ETT53_RS05430	COG2357	RelA SpoT domain protein
ETT53_RS05435	COG0737	Belongs to the 5'-nucleotidase family
ETT53_RS05440	COG0242	peptide deformylase activity
ETT53_RS05450	COG0488	(ABC) transporter
ETT53_RS05490	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT53_RS05490	COG1388	LysM domain
ETT53_RS05495	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT53_RS05495	COG1388	LysM domain
ETT53_RS05500	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT53_RS05500	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT53_RS05500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETT53_RS05505	COG1105	Belongs to the carbohydrate kinase PfkB family
ETT53_RS05510	COG1349	DNA-binding transcription factor activity
ETT53_RS05560	COG1837	Belongs to the UPF0109 family
ETT53_RS05570	COG0584	glycerophosphoryl diester phosphodiesterase
ETT53_RS05575	COG0577	efflux transmembrane transporter activity
ETT53_RS05580	COG1136	(ABC) transporter
ETT53_RS05585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETT53_RS05620	COG0564	pseudouridine synthase activity
ETT53_RS05630	COG0583	DNA-binding transcription factor activity
ETT53_RS05635	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETT53_RS05660	COG1104	cysteine desulfurase activity
ETT53_RS05670	COG0285	dihydrofolate synthase activity
ETT53_RS05675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETT53_RS05695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETT53_RS05700	COG1368	sulfuric ester hydrolase activity
ETT53_RS05760	COG1216	Glycosyl transferase, family 2
ETT53_RS05805	COG5433	transposase activity
ETT53_RS05815	COG2151	metal-sulfur cluster biosynthetic enzyme
ETT53_RS05820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETT53_RS05825	COG0358	DNA primase activity
ETT53_RS05830	COG1970	mechanosensitive ion channel activity
ETT53_RS05845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT53_RS05860	COG2321	neutral zinc metallopeptidase
ETT53_RS05870	COG0577	efflux transmembrane transporter activity
ETT53_RS05955	COG1597	lipid kinase activity
ETT53_RS05965	COG4708	membrane
ETT53_RS05990	COG1131	(ABC) transporter
ETT53_RS06085	COG0038	chloride channel
ETT53_RS06095	COG0716	FMN binding
ETT53_RS06105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETT53_RS06115	COG2222	sugar isomerase
ETT53_RS06120	COG2188	Transcriptional regulator
ETT53_RS06155	COG0436	Aminotransferase
ETT53_RS06160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETT53_RS06160	COG1199	ATP-dependent helicase activity
ETT53_RS06175	COG2177	Part of the ABC transporter FtsEX involved in
ETT53_RS06180	COG2884	Cell division ATP-binding protein ftsE
ETT53_RS06190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETT53_RS06200	COG0546	phosphoglycolate phosphatase activity
ETT53_RS06205	COG0800	Aldolase
ETT53_RS06220	COG1028	Short-chain dehydrogenase reductase Sdr
ETT53_RS06235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT53_RS06240	COG3715	PTS system
ETT53_RS06245	COG3716	PTS system mannose fructose sorbose family IID component
ETT53_RS06255	COG1609	Transcriptional regulator
ETT53_RS06270	COG1078	dGTPase activity
ETT53_RS06305	COG0772	Belongs to the SEDS family
ETT53_RS06315	COG1164	Oligoendopeptidase f
ETT53_RS06320	COG0386	Belongs to the glutathione peroxidase family
ETT53_RS06350	COG0588	phosphoglycerate mutase activity
ETT53_RS06365	COG4443	Transcriptional Coactivator p15 (PC4)
ETT53_RS06370	COG0826	peptidase U32
ETT53_RS06415	COG2183	response to ionizing radiation
ETT53_RS06425	COG0701	Predicted permease
ETT53_RS06430	COG3689	TIGRFAM TIGR03943 family protein
ETT53_RS06440	COG2190	(PTS) system
ETT53_RS06440	COG1263	PTS System
ETT53_RS06440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT53_RS06445	COG3711	transcriptional antiterminator
ETT53_RS06450	COG0477	Major facilitator Superfamily
ETT53_RS06455	COG0552	protein localization to endoplasmic reticulum
ETT53_RS06460	COG0561	phosphatase activity
ETT53_RS06465	COG0561	phosphatase activity
ETT53_RS06565	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETT53_RS06580	COG1196	nuclear chromosome segregation
ETT53_RS06590	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETT53_RS06595	COG5002	protein histidine kinase activity
ETT53_RS06600	COG0745	RESPONSE REGULATOR receiver
ETT53_RS06615	COG0183	Belongs to the thiolase family
ETT53_RS06635	COG4555	ABC transporter
ETT53_RS06645	COG0438	transferase activity, transferring glycosyl groups
ETT53_RS06655	COG1609	Transcriptional regulator
ETT53_RS06660	COG0006	proline dipeptidase activity
ETT53_RS06665	COG0778	Nitroreductase
ETT53_RS06670	COG0346	lactoylglutathione lyase activity
ETT53_RS06675	COG0463	Glycosyl transferase, family 2
ETT53_RS06705	COG0557	exoribonuclease II activity
ETT53_RS06720	COG2814	Major facilitator Superfamily
ETT53_RS06725	COG0433	COG0433 Predicted ATPase
ETT53_RS06830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETT53_RS06840	COG1573	uracil-dna glycosylase
ETT53_RS06845	COG1702	phosphate starvation-inducible protein PhoH
ETT53_RS06935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETT53_RS06945	COG0494	nUDIX hydrolase
ETT53_RS06960	COG0673	inositol 2-dehydrogenase activity
ETT53_RS06965	COG1028	Short-chain dehydrogenase reductase Sdr
ETT53_RS07085	COG1304	FMN binding
ETT53_RS07095	COG0708	Exodeoxyribonuclease III
ETT53_RS07100	COG1393	Belongs to the ArsC family
ETT53_RS07130	COG0470	DNA polymerase III
ETT53_RS07165	COG2244	polysaccharide biosynthetic process
ETT53_RS07175	COG1120	ATPase activity
ETT53_RS07180	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETT53_RS07185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT53_RS07190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT53_RS07205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT53_RS07210	COG1253	flavin adenine dinucleotide binding
ETT53_RS07215	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETT53_RS07220	COG1242	4 iron, 4 sulfur cluster binding
ETT53_RS07225	COG0671	phosphoesterase, PA-phosphatase related
ETT53_RS07230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETT53_RS07245	COG1187	pseudouridine synthase activity
ETT53_RS07300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT53_RS07305	COG1254	Belongs to the acylphosphatase family
ETT53_RS07320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETT53_RS07340	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETT53_RS07350	COG1484	DNA-dependent DNA replication
ETT53_RS07370	COG0745	RESPONSE REGULATOR receiver
ETT53_RS07385	COG1704	LemA family
ETT53_RS07395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETT53_RS07400	COG0569	domain protein
ETT53_RS07410	COG1114	Component of the transport system for branched-chain amino acids
ETT53_RS07425	COG1464	Belongs to the NlpA lipoprotein family
ETT53_RS07430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT53_RS07450	COG2226	methyltransferase
ETT53_RS07455	COG0799	negative regulation of ribosome biogenesis
ETT53_RS07460	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETT53_RS07470	COG1534	Rna-binding protein
ETT53_RS07475	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETT53_RS07480	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETT53_RS07520	COG1929	Belongs to the glycerate kinase type-1 family
ETT53_RS07525	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETT53_RS07560	COG1136	(ABC) transporter
ETT53_RS07565	COG1132	(ABC) transporter
ETT53_RS07585	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT53_RS07585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT53_RS07590	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT53_RS07640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETT53_RS07645	COG1476	TRANSCRIPTIONal
ETT53_RS07665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT53_RS07675	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETT53_RS07695	COG1045	serine acetyltransferase
ETT53_RS07710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETT53_RS07725	COG3711	transcriptional antiterminator
ETT53_RS07755	COG1846	Transcriptional regulator
ETT53_RS07775	COG4589	Belongs to the CDS family
ETT53_RS07785	COG1862	Preprotein translocase
ETT53_RS07795	COG1523	belongs to the glycosyl hydrolase 13 family
ETT53_RS07810	COG3842	ATPase activity
ETT53_RS07850	COG1263	PTS System
ETT53_RS07850	COG2190	(PTS) system
ETT53_RS07850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT53_RS07855	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETT53_RS07885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETT53_RS07890	COG0512	Glutamine amidotransferase of anthranilate synthase
ETT53_RS07895	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETT53_RS07930	COG0601	transmembrane transport
ETT53_RS07960	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETT53_RS07965	COG5433	transposase activity
ETT53_RS07995	COG3711	transcriptional antiterminator
ETT53_RS08010	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT53_RS08010	COG3942	CHAP domain
ETT53_RS08015	COG2205	protein histidine kinase activity
ETT53_RS08025	COG0577	efflux transmembrane transporter activity
ETT53_RS08030	COG1136	(ABC) transporter
ETT53_RS08105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETT53_RS08120	COG1882	Formate acetyltransferase
ETT53_RS08125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT53_RS08135	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT53_RS08140	COG2390	Transcriptional regulator
ETT53_RS08145	COG1349	DNA-binding transcription factor activity
ETT53_RS08150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT53_RS08170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT53_RS08185	COG0564	pseudouridine synthase activity
ETT53_RS08220	COG0542	response to heat
ETT53_RS08225	COG4463	regulation of RNA biosynthetic process
ETT53_RS08245	COG0450	alkyl hydroperoxide reductase
ETT53_RS08260	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETT53_RS08270	COG3404	Formiminotransferase-cyclodeaminase
ETT53_RS08285	COG0531	amino acid
ETT53_RS08315	COG3590	peptidase
ETT53_RS08320	COG0366	Alpha amylase catalytic
ETT53_RS08325	COG1263	PTS System
ETT53_RS08325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT53_RS08330	COG2188	Transcriptional regulator
ETT53_RS08340	COG1733	regulation of RNA biosynthetic process
ETT53_RS08345	COG2514	catechol 2,3-dioxygenase activity
ETT53_RS08355	COG0602	queuosine metabolic process
ETT53_RS08370	COG1328	CTP reductase activity
ETT53_RS08395	COG1393	Belongs to the ArsC family
ETT53_RS08410	COG0519	Catalyzes the synthesis of GMP from XMP
ETT53_RS08455	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT53_RS08460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT53_RS08465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT53_RS08550	COG1511	domain protein
ETT53_RS08570	COG0305	Participates in initiation and elongation during chromosome replication
ETT53_RS08600	COG1760	l-serine dehydratase
ETT53_RS08605	COG1760	l-serine dehydratase
ETT53_RS08610	COG0741	lytic transglycosylase activity
ETT53_RS08615	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETT53_RS08630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETT53_RS08640	COG0612	Peptidase, M16
ETT53_RS08650	COG1215	transferase activity, transferring glycosyl groups
ETT53_RS08660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETT53_RS08680	COG0517	IMP dehydrogenase activity
ETT53_RS08680	COG0516	GMP reductase activity
ETT53_RS08690	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT53_RS08695	COG0488	(ABC) transporter
ETT53_RS08735	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETT53_RS08740	COG1475	DNA binding