locus-tag	class	description
ETT63_RS00010	COG0592	DNA-directed DNA polymerase activity
ETT63_RS00020	COG0012	GTP binding
ETT63_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETT63_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETT63_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETT63_RS00065	COG0531	amino acid
ETT63_RS00245	COG3942	CHAP domain
ETT63_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETT63_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETT63_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETT63_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETT63_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETT63_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETT63_RS00355	COG1454	alcohol dehydrogenase
ETT63_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
ETT63_RS00360	COG1064	alcohol dehydrogenase
ETT63_RS00365	COG0534	Mate efflux family protein
ETT63_RS00475	COG0201	protein transport
ETT63_RS00620	COG1121	(ABC) transporter
ETT63_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETT63_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT63_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETT63_RS00665	COG1459	type II secretion system
ETT63_RS00670	COG4537	Required for transformation and DNA binding
ETT63_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETT63_RS00715	COG1363	Peptidase, m42
ETT63_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT63_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETT63_RS00745	COG1428	Deoxynucleoside kinase
ETT63_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETT63_RS00795	COG4509	Sortase family
ETT63_RS00820	COG2031	fatty acid transporter
ETT63_RS00835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETT63_RS00850	COG0251	oxidation-reduction process
ETT63_RS00865	COG1269	ATP hydrolysis coupled proton transport
ETT63_RS00870	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETT63_RS00880	COG1527	subunit (C
ETT63_RS00885	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
ETT63_RS00920	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT63_RS00965	COG0626	cystathionine gamma-synthase activity
ETT63_RS00995	COG3623	hexulose-6-phosphate isomerase
ETT63_RS01020	COG3448	diguanylate cyclase activity
ETT63_RS01020	COG4175	Glycine betaine
ETT63_RS01030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT63_RS01030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT63_RS01050	COG3969	phosphoadenosine phosphosulfate
ETT63_RS01055	COG1475	DNA binding
ETT63_RS01075	COG0157	Belongs to the NadC ModD family
ETT63_RS01105	COG1268	BioY protein
ETT63_RS01110	COG1234	tRNA 3'-trailer cleavage
ETT63_RS01145	COG0457	Tetratricopeptide repeat
ETT63_RS01145	COG0705	Rhomboid family
ETT63_RS01165	COG1132	(ABC) transporter
ETT63_RS01170	COG1132	(ABC) transporter
ETT63_RS01180	COG0756	dUTP diphosphatase activity
ETT63_RS01205	COG3290	protein histidine kinase activity
ETT63_RS01230	COG1847	R3H domain protein
ETT63_RS01250	COG1175	transmembrane transport
ETT63_RS01255	COG0395	ABC-type sugar transport system, permease component
ETT63_RS01265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETT63_RS01280	COG0084	hydrolase, TatD family'
ETT63_RS01305	COG1564	THIamine pyrophosphokinase
ETT63_RS01320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETT63_RS01360	COG0765	amino acid transport
ETT63_RS01380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETT63_RS01390	COG0719	Fe-S assembly protein
ETT63_RS01395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETT63_RS01410	COG1686	Belongs to the peptidase S11 family
ETT63_RS01415	COG1686	Belongs to the peptidase S11 family
ETT63_RS01420	COG4166	transmembrane transport
ETT63_RS01425	COG0601	transmembrane transport
ETT63_RS01430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETT63_RS01435	COG0444	Belongs to the ABC transporter superfamily
ETT63_RS01495	COG0351	phosphomethylpyrimidine kinase
ETT63_RS01500	COG4720	Psort location CytoplasmicMembrane, score
ETT63_RS01510	COG0668	transmembrane transport
ETT63_RS01565	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ETT63_RS01580	COG0789	Transcriptional regulator
ETT63_RS01585	COG0174	glutamine synthetase
ETT63_RS01600	COG1214	PFAM Peptidase M22, glycoprotease
ETT63_RS01605	COG0456	acetyltransferase
ETT63_RS01625	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ETT63_RS01630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETT63_RS01640	COG2081	HI0933 family
ETT63_RS01655	COG0789	Transcriptional regulator
ETT63_RS01680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETT63_RS01685	COG2814	Major facilitator Superfamily
ETT63_RS01695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT63_RS01710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETT63_RS01715	COG1882	Formate acetyltransferase
ETT63_RS01730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETT63_RS01735	COG0681	Belongs to the peptidase S26 family
ETT63_RS01765	COG3118	belongs to the thioredoxin family
ETT63_RS01775	COG1194	a g-specific adenine glycosylase
ETT63_RS01815	COG0006	proline dipeptidase activity
ETT63_RS01820	COG2131	deaminase
ETT63_RS01840	COG1609	Transcriptional regulator
ETT63_RS01845	COG1621	beta-fructofuranosidase activity
ETT63_RS01850	COG1263	PTS System
ETT63_RS01850	COG2190	(PTS) system
ETT63_RS01850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT63_RS01860	COG1940	carbohydrate kinase activity
ETT63_RS01865	COG1482	cell wall glycoprotein biosynthetic process
ETT63_RS01885	COG3942	CHAP domain
ETT63_RS01885	COG1388	LysM domain
ETT63_RS01915	COG4988	ABC transporter
ETT63_RS01920	COG1132	(ABC) transporter
ETT63_RS01935	COG1129	ABC transporter
ETT63_RS01945	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETT63_RS01960	COG0252	asparaginase activity
ETT63_RS01965	COG0561	phosphatase activity
ETT63_RS01975	COG0436	Aminotransferase
ETT63_RS01985	COG1335	isochorismatase
ETT63_RS02020	COG2261	transglycosylase associated protein
ETT63_RS02025	COG0588	phosphoglycerate mutase activity
ETT63_RS02055	COG0484	heat shock protein binding
ETT63_RS02060	COG1024	Enoyl-CoA hydratase
ETT63_RS02085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETT63_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
ETT63_RS02095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETT63_RS02110	COG0439	Biotin carboxylase
ETT63_RS02135	COG3716	PTS system mannose fructose sorbose family IID component
ETT63_RS02140	COG3715	PTS system
ETT63_RS02150	COG0561	phosphatase activity
ETT63_RS02155	COG2252	PERMEase
ETT63_RS02160	COG0802	atpase or kinase
ETT63_RS02170	COG1316	TRANSCRIPTIONal
ETT63_RS02180	COG0537	adenosine 5'-monophosphoramidase activity
ETT63_RS02185	COG1131	(ABC) transporter
ETT63_RS02190	COG4473	ABC transporter
ETT63_RS02215	COG0195	Participates in both transcription termination and antitermination
ETT63_RS02220	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETT63_RS02250	COG2217	Heavy metal translocating P-type atpase
ETT63_RS02310	COG2860	membrane
ETT63_RS02315	COG0561	phosphatase activity
ETT63_RS02335	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETT63_RS02345	COG0656	L-ascorbic acid biosynthetic process
ETT63_RS02350	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETT63_RS02390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT63_RS02395	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETT63_RS02420	COG1131	(ABC) transporter
ETT63_RS02455	COG0768	penicillin binding
ETT63_RS02465	COG0513	Belongs to the DEAD box helicase family
ETT63_RS02475	COG1126	abc transporter atp-binding protein
ETT63_RS02485	COG0492	ferredoxin-NADP+ reductase activity
ETT63_RS02490	COG1113	amino acid transport
ETT63_RS02495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETT63_RS02505	COG3579	cysteine-type endopeptidase activity
ETT63_RS02510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT63_RS02535	COG0116	Belongs to the methyltransferase superfamily
ETT63_RS02550	COG2610	gluconate transmembrane transporter activity
ETT63_RS02555	COG1028	Short-chain dehydrogenase reductase Sdr
ETT63_RS02570	COG0183	Belongs to the thiolase family
ETT63_RS02575	COG0583	DNA-binding transcription factor activity
ETT63_RS02595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETT63_RS02605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETT63_RS02605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT63_RS02615	COG0515	serine threonine protein kinase
ETT63_RS02615	COG2815	serine threonine protein kinase
ETT63_RS02625	COG4585	Histidine kinase
ETT63_RS02630	COG2197	response regulator
ETT63_RS02640	COG1098	S1 RNA binding domain
ETT63_RS02650	COG1739	Uncharacterized protein family UPF0029
ETT63_RS02655	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETT63_RS02760	COG0383	alpha-mannosidase activity
ETT63_RS02775	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ETT63_RS02780	COG2723	6-phospho-beta-galactosidase activity
ETT63_RS02785	COG1940	carbohydrate kinase activity
ETT63_RS02790	COG1175	transmembrane transport
ETT63_RS02795	COG0395	ABC-type sugar transport system, permease component
ETT63_RS02800	COG1653	transport
ETT63_RS02810	COG2972	Histidine kinase
ETT63_RS02815	COG4753	response regulator
ETT63_RS02815	COG2207	Transcriptional regulator
ETT63_RS02820	COG3250	beta-galactosidase activity
ETT63_RS02830	COG2226	methyltransferase
ETT63_RS02850	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETT63_RS02850	COG1605	Chorismate mutase
ETT63_RS02920	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ETT63_RS02925	COG0785	Cytochrome C biogenesis protein
ETT63_RS02930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT63_RS02945	COG2972	Histidine kinase
ETT63_RS02970	COG2235	arginine
ETT63_RS02975	COG0454	-acetyltransferase
ETT63_RS02985	COG1288	antiporter activity
ETT63_RS02990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT63_RS02995	COG0549	Belongs to the carbamate kinase family
ETT63_RS03005	COG0742	ribosomal rna small subunit methyltransferase
ETT63_RS03015	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETT63_RS03020	COG1609	Transcriptional regulator
ETT63_RS03025	COG4470	Protein conserved in bacteria
ETT63_RS03040	COG0783	Belongs to the Dps family
ETT63_RS03050	COG1940	carbohydrate kinase activity
ETT63_RS03055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETT63_RS03060	COG1217	gtp-binding protein TYPA
ETT63_RS03095	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETT63_RS03110	COG2302	S4 RNA-binding domain
ETT63_RS03115	COG3599	regulation of cell shape
ETT63_RS03130	COG0494	nUDIX hydrolase
ETT63_RS03135	COG0542	response to heat
ETT63_RS03140	COG4703	Protein of unknown function (DUF1797)
ETT63_RS03145	COG0765	amino acid transport
ETT63_RS03155	COG0415	Belongs to the DNA photolyase family
ETT63_RS03160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT63_RS03185	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETT63_RS03190	COG1438	arginine binding
ETT63_RS03195	COG0497	DNA recombination
ETT63_RS03210	COG2755	lipolytic protein G-D-S-L family
ETT63_RS03225	COG2217	Heavy metal translocating P-type atpase
ETT63_RS03240	COG1827	regulation of RNA biosynthetic process
ETT63_RS03250	COG2116	formate transmembrane transporter activity
ETT63_RS03255	COG0768	penicillin binding
ETT63_RS03270	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT63_RS03290	COG0513	Belongs to the DEAD box helicase family
ETT63_RS03305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ETT63_RS03310	COG0204	Acyl-transferase
ETT63_RS03315	COG1596	polysaccharide export
ETT63_RS03315	COG1555	photosystem II stabilization
ETT63_RS03320	COG0658	competence protein
ETT63_RS03320	COG2333	competence protein COMEC
ETT63_RS03365	COG1187	pseudouridine synthase activity
ETT63_RS03380	COG2223	nitrite transmembrane transporter activity
ETT63_RS03385	COG4122	O-methyltransferase activity
ETT63_RS03400	COG1476	TRANSCRIPTIONal
ETT63_RS03445	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETT63_RS03450	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETT63_RS03455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETT63_RS03475	COG0726	polysaccharide deacetylase
ETT63_RS03480	COG0513	Belongs to the DEAD box helicase family
ETT63_RS03500	COG1956	GAF domain-containing protein
ETT63_RS03505	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETT63_RS03515	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETT63_RS03515	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETT63_RS03535	COG2211	Major facilitator Superfamily
ETT63_RS03545	COG3250	beta-galactosidase activity
ETT63_RS03550	COG2186	Transcriptional regulator
ETT63_RS03555	COG0800	Aldolase
ETT63_RS03570	COG1028	Short-chain dehydrogenase reductase Sdr
ETT63_RS03600	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETT63_RS03605	COG4109	DRTGG domain
ETT63_RS03655	COG2814	Major facilitator Superfamily
ETT63_RS03665	COG1187	pseudouridine synthase activity
ETT63_RS03695	COG2723	6-phospho-beta-galactosidase activity
ETT63_RS03715	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT63_RS03725	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT63_RS03730	COG1126	abc transporter atp-binding protein
ETT63_RS03735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT63_RS03755	COG1696	Membrane protein involved in D-alanine export
ETT63_RS03765	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETT63_RS03770	COG0657	acetylesterase activity
ETT63_RS03790	COG3833	ABC-type maltose transport systems, permease component
ETT63_RS03795	COG1175	transmembrane transport
ETT63_RS03800	COG2182	Extracellular solute-binding protein
ETT63_RS03805	COG1609	Transcriptional regulator
ETT63_RS03810	COG1640	4-alpha-glucanotransferase
ETT63_RS03815	COG0058	SHG alpha-glucan phosphorylase activity
ETT63_RS03860	COG1396	sequence-specific DNA binding
ETT63_RS03865	COG3561	AntA/AntB antirepressor
ETT63_RS04140	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT63_RS04185	COG1131	(ABC) transporter
ETT63_RS04190	COG1725	Transcriptional regulator
ETT63_RS04205	COG0469	pyruvate kinase activity
ETT63_RS04220	COG2824	Alkylphosphonate utilization operon protein PhnA
ETT63_RS04225	COG0765	amino acid transport
ETT63_RS04230	COG1126	abc transporter atp-binding protein
ETT63_RS04235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT63_RS04245	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETT63_RS04250	COG1115	amino acid carrier protein
ETT63_RS04300	COG1136	(ABC) transporter
ETT63_RS04300	COG4591	ABC-type transport system involved in lipoprotein release permease component
ETT63_RS04330	COG0196	riboflavin kinase activity
ETT63_RS04345	COG0483	inositol monophosphate 1-phosphatase activity
ETT63_RS04350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT63_RS04350	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ETT63_RS04360	COG0573	inorganic phosphate transmembrane transporter activity
ETT63_RS04365	COG0581	inorganic phosphate transmembrane transporter activity
ETT63_RS04380	COG0704	Plays a role in the regulation of phosphate uptake
ETT63_RS04395	COG0745	RESPONSE REGULATOR receiver
ETT63_RS04400	COG5002	protein histidine kinase activity
ETT63_RS04415	COG2813	Specifically methylates the guanine in position
ETT63_RS04420	COG0295	cytidine deaminase activity
ETT63_RS04425	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT63_RS04430	COG3845	ABC transporter
ETT63_RS04435	COG4603	Belongs to the binding-protein-dependent transport system permease family
ETT63_RS04440	COG1079	Belongs to the binding-protein-dependent transport system permease family
ETT63_RS04445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT63_RS04450	COG4684	Psort location CytoplasmicMembrane, score
ETT63_RS04455	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETT63_RS04475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETT63_RS04505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETT63_RS04510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETT63_RS04510	COG1328	CTP reductase activity
ETT63_RS04520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETT63_RS04525	COG0352	thiamine-phosphate diphosphorylase activity
ETT63_RS04525	COG0351	phosphomethylpyrimidine kinase
ETT63_RS04535	COG0488	(ABC) transporter
ETT63_RS04555	COG2188	Transcriptional regulator
ETT63_RS04565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETT63_RS04585	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ETT63_RS04615	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT63_RS04620	COG0511	ligase activity, forming carbon-carbon bonds
ETT63_RS04630	COG2851	Citrate transporter
ETT63_RS04645	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT63_RS04650	COG0511	ligase activity, forming carbon-carbon bonds
ETT63_RS04695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETT63_RS04720	COG1272	protein, Hemolysin III
ETT63_RS04740	COG0346	lactoylglutathione lyase activity
ETT63_RS04745	COG3764	Sortase (surface protein transpeptidase)
ETT63_RS04765	COG1132	(ABC) transporter
ETT63_RS04770	COG1132	(ABC) transporter
ETT63_RS04800	COG2890	protein-(glutamine-N5) methyltransferase activity
ETT63_RS04825	COG2233	PERMEase
ETT63_RS04845	COG1174	glycine betaine transport
ETT63_RS04860	COG4221	oxidoreductase activity
ETT63_RS04865	COG0280	phosphate acetyltransferase
ETT63_RS04870	COG0564	pseudouridine synthase activity
ETT63_RS04880	COG2357	RelA SpoT domain protein
ETT63_RS04895	COG1104	cysteine desulfurase activity
ETT63_RS04910	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ETT63_RS04920	COG0628	permease
ETT63_RS04930	COG0038	chloride channel
ETT63_RS04935	COG3700	Belongs to the class B bacterial acid phosphatase family
ETT63_RS04950	COG3493	citrate carrier protein
ETT63_RS04955	COG3290	protein histidine kinase activity
ETT63_RS04960	COG4565	transcriptional regulatory protein
ETT63_RS04970	COG1177	transmembrane transport
ETT63_RS04975	COG1176	ABC-type spermidine putrescine transport system, permease component I
ETT63_RS04990	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETT63_RS05010	COG0285	dihydrofolate synthase activity
ETT63_RS05040	COG1396	sequence-specific DNA binding
ETT63_RS05055	COG1131	(ABC) transporter
ETT63_RS05120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT63_RS05135	COG1012	belongs to the aldehyde dehydrogenase family
ETT63_RS05145	COG4753	response regulator
ETT63_RS05145	COG2207	Transcriptional regulator
ETT63_RS05150	COG2972	Histidine kinase
ETT63_RS05155	COG3716	PTS system mannose fructose sorbose family IID component
ETT63_RS05160	COG3715	PTS system
ETT63_RS05210	COG0647	UMP catabolic process
ETT63_RS05220	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETT63_RS05240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETT63_RS05245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT63_RS05250	COG3442	glutamine amidotransferase
ETT63_RS05255	COG0095	Lipoate-protein ligase
ETT63_RS05260	COG5492	domain, Protein
ETT63_RS05280	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT63_RS05285	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT63_RS05285	COG0022	dehydrogenase e1 component
ETT63_RS05290	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETT63_RS05295	COG0488	(ABC) transporter
ETT63_RS05315	COG1129	ABC transporter
ETT63_RS05335	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ETT63_RS05340	COG0457	Tetratricopeptide repeat
ETT63_RS05345	COG0628	permease
ETT63_RS05350	COG1051	belongs to the nudix hydrolase family
ETT63_RS05355	COG1088	dTDP-glucose 4,6-dehydratase activity
ETT63_RS05365	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETT63_RS05370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETT63_RS05380	COG2384	SAM-dependent methyltransferase
ETT63_RS05385	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETT63_RS05400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETT63_RS05400	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETT63_RS05405	COG0300	oxidoreductase activity
ETT63_RS05420	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETT63_RS05465	COG0539	negative regulation of cytoplasmic translation
ETT63_RS05485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETT63_RS05495	COG0187	DNA topoisomerase II activity
ETT63_RS05515	COG0765	amino acid transport
ETT63_RS05520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT63_RS05545	COG0583	DNA-binding transcription factor activity
ETT63_RS05605	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETT63_RS05615	COG3425	synthase
ETT63_RS05650	COG0745	RESPONSE REGULATOR receiver
ETT63_RS05655	COG2357	RelA SpoT domain protein
ETT63_RS05665	COG0582	viral genome integration into host DNA
ETT63_RS05775	COG0242	peptide deformylase activity
ETT63_RS05785	COG0488	(ABC) transporter
ETT63_RS05825	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT63_RS05825	COG1388	LysM domain
ETT63_RS05830	COG1388	LysM domain
ETT63_RS05830	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT63_RS05835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT63_RS05835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETT63_RS05835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT63_RS05840	COG1105	Belongs to the carbohydrate kinase PfkB family
ETT63_RS05845	COG1349	DNA-binding transcription factor activity
ETT63_RS05895	COG1837	Belongs to the UPF0109 family
ETT63_RS05905	COG0584	glycerophosphoryl diester phosphodiesterase
ETT63_RS05910	COG0577	efflux transmembrane transporter activity
ETT63_RS05915	COG1136	(ABC) transporter
ETT63_RS05920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETT63_RS05955	COG0564	pseudouridine synthase activity
ETT63_RS05965	COG0583	DNA-binding transcription factor activity
ETT63_RS05970	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETT63_RS05995	COG1104	cysteine desulfurase activity
ETT63_RS06005	COG0285	dihydrofolate synthase activity
ETT63_RS06010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETT63_RS06030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETT63_RS06035	COG1368	sulfuric ester hydrolase activity
ETT63_RS06095	COG1216	Glycosyl transferase, family 2
ETT63_RS06140	COG2151	metal-sulfur cluster biosynthetic enzyme
ETT63_RS06145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETT63_RS06150	COG0358	DNA primase activity
ETT63_RS06155	COG1970	mechanosensitive ion channel activity
ETT63_RS06165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT63_RS06180	COG2321	neutral zinc metallopeptidase
ETT63_RS06190	COG0577	efflux transmembrane transporter activity
ETT63_RS06275	COG1597	lipid kinase activity
ETT63_RS06285	COG4708	membrane
ETT63_RS06310	COG1131	(ABC) transporter
ETT63_RS06400	COG0038	chloride channel
ETT63_RS06410	COG0716	FMN binding
ETT63_RS06415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETT63_RS06425	COG2222	sugar isomerase
ETT63_RS06430	COG2188	Transcriptional regulator
ETT63_RS06465	COG0436	Aminotransferase
ETT63_RS06470	COG1199	ATP-dependent helicase activity
ETT63_RS06470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETT63_RS06485	COG2177	Part of the ABC transporter FtsEX involved in
ETT63_RS06490	COG2884	Cell division ATP-binding protein ftsE
ETT63_RS06500	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETT63_RS06510	COG0546	phosphoglycolate phosphatase activity
ETT63_RS06515	COG0800	Aldolase
ETT63_RS06530	COG1028	Short-chain dehydrogenase reductase Sdr
ETT63_RS06545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT63_RS06550	COG3715	PTS system
ETT63_RS06555	COG3716	PTS system mannose fructose sorbose family IID component
ETT63_RS06565	COG1609	Transcriptional regulator
ETT63_RS06580	COG1078	dGTPase activity
ETT63_RS06615	COG0772	Belongs to the SEDS family
ETT63_RS06625	COG1164	Oligoendopeptidase f
ETT63_RS06630	COG0386	Belongs to the glutathione peroxidase family
ETT63_RS06675	COG4443	Transcriptional Coactivator p15 (PC4)
ETT63_RS06680	COG0826	peptidase U32
ETT63_RS06725	COG2183	response to ionizing radiation
ETT63_RS06735	COG0701	Predicted permease
ETT63_RS06740	COG3689	TIGRFAM TIGR03943 family protein
ETT63_RS06750	COG1263	PTS System
ETT63_RS06750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT63_RS06750	COG2190	(PTS) system
ETT63_RS06755	COG3711	transcriptional antiterminator
ETT63_RS06760	COG0477	Major facilitator Superfamily
ETT63_RS06765	COG0552	protein localization to endoplasmic reticulum
ETT63_RS06770	COG0561	phosphatase activity
ETT63_RS06775	COG0561	phosphatase activity
ETT63_RS06885	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETT63_RS06900	COG1196	nuclear chromosome segregation
ETT63_RS06910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETT63_RS06915	COG5002	protein histidine kinase activity
ETT63_RS06920	COG0745	RESPONSE REGULATOR receiver
ETT63_RS06935	COG0183	Belongs to the thiolase family
ETT63_RS06955	COG4555	ABC transporter
ETT63_RS06965	COG0438	transferase activity, transferring glycosyl groups
ETT63_RS06975	COG1609	Transcriptional regulator
ETT63_RS06980	COG0006	proline dipeptidase activity
ETT63_RS06985	COG0778	Nitroreductase
ETT63_RS06995	COG0463	Glycosyl transferase, family 2
ETT63_RS07025	COG0557	exoribonuclease II activity
ETT63_RS07040	COG2814	Major facilitator Superfamily
ETT63_RS07045	COG0433	COG0433 Predicted ATPase
ETT63_RS07125	COG2274	protein secretion by the type I secretion system
ETT63_RS07130	COG2274	protein secretion by the type I secretion system
ETT63_RS07155	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETT63_RS07165	COG1573	uracil-dna glycosylase
ETT63_RS07170	COG1702	phosphate starvation-inducible protein PhoH
ETT63_RS07260	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETT63_RS07270	COG0494	nUDIX hydrolase
ETT63_RS07285	COG0673	inositol 2-dehydrogenase activity
ETT63_RS07290	COG1028	Short-chain dehydrogenase reductase Sdr
ETT63_RS07400	COG1304	FMN binding
ETT63_RS07410	COG0708	Exodeoxyribonuclease III
ETT63_RS07415	COG1393	Belongs to the ArsC family
ETT63_RS07445	COG0470	DNA polymerase III
ETT63_RS07475	COG2244	polysaccharide biosynthetic process
ETT63_RS07485	COG1120	ATPase activity
ETT63_RS07490	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETT63_RS07495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT63_RS07500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT63_RS07515	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT63_RS07520	COG1253	flavin adenine dinucleotide binding
ETT63_RS07525	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETT63_RS07530	COG1242	4 iron, 4 sulfur cluster binding
ETT63_RS07535	COG0671	phosphoesterase, PA-phosphatase related
ETT63_RS07540	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETT63_RS07555	COG1187	pseudouridine synthase activity
ETT63_RS07610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT63_RS07615	COG1254	Belongs to the acylphosphatase family
ETT63_RS07630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETT63_RS07650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETT63_RS07660	COG1484	DNA-dependent DNA replication
ETT63_RS07680	COG0745	RESPONSE REGULATOR receiver
ETT63_RS07695	COG1704	LemA family
ETT63_RS07705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETT63_RS07710	COG0569	domain protein
ETT63_RS07720	COG1114	Component of the transport system for branched-chain amino acids
ETT63_RS07735	COG1464	Belongs to the NlpA lipoprotein family
ETT63_RS07740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT63_RS07760	COG2226	methyltransferase
ETT63_RS07765	COG0799	negative regulation of ribosome biogenesis
ETT63_RS07770	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETT63_RS07780	COG1534	Rna-binding protein
ETT63_RS07785	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETT63_RS07790	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETT63_RS07830	COG1929	Belongs to the glycerate kinase type-1 family
ETT63_RS07835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETT63_RS07865	COG0577	efflux transmembrane transporter activity
ETT63_RS07870	COG1136	(ABC) transporter
ETT63_RS07875	COG2274	protein secretion by the type I secretion system
ETT63_RS07895	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT63_RS07895	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT63_RS07900	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT63_RS07955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETT63_RS07960	COG1476	TRANSCRIPTIONal
ETT63_RS07980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT63_RS07990	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETT63_RS08010	COG1045	serine acetyltransferase
ETT63_RS08025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETT63_RS08040	COG3711	transcriptional antiterminator
ETT63_RS08070	COG1846	Transcriptional regulator
ETT63_RS08090	COG4589	Belongs to the CDS family
ETT63_RS08100	COG1862	Preprotein translocase
ETT63_RS08115	COG1523	belongs to the glycosyl hydrolase 13 family
ETT63_RS08130	COG3842	ATPase activity
ETT63_RS08170	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT63_RS08170	COG1263	PTS System
ETT63_RS08170	COG2190	(PTS) system
ETT63_RS08175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETT63_RS08190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETT63_RS08195	COG0512	Glutamine amidotransferase of anthranilate synthase
ETT63_RS08200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETT63_RS08240	COG0601	transmembrane transport
ETT63_RS08250	COG0444	Belongs to the ABC transporter superfamily
ETT63_RS08270	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETT63_RS08280	COG1404	Belongs to the peptidase S8 family
ETT63_RS08280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ETT63_RS08300	COG3711	transcriptional antiterminator
ETT63_RS08315	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT63_RS08315	COG3942	CHAP domain
ETT63_RS08320	COG2205	protein histidine kinase activity
ETT63_RS08325	COG0745	RESPONSE REGULATOR receiver
ETT63_RS08330	COG0577	efflux transmembrane transporter activity
ETT63_RS08335	COG1136	(ABC) transporter
ETT63_RS08410	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETT63_RS08425	COG1882	Formate acetyltransferase
ETT63_RS08430	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT63_RS08435	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT63_RS08440	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT63_RS08445	COG2390	Transcriptional regulator
ETT63_RS08450	COG1349	DNA-binding transcription factor activity
ETT63_RS08455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT63_RS08475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT63_RS08490	COG0564	pseudouridine synthase activity
ETT63_RS08525	COG0542	response to heat
ETT63_RS08530	COG4463	regulation of RNA biosynthetic process
ETT63_RS08555	COG0450	alkyl hydroperoxide reductase
ETT63_RS08570	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETT63_RS08580	COG3404	Formiminotransferase-cyclodeaminase
ETT63_RS08595	COG0531	amino acid
ETT63_RS08625	COG3590	peptidase
ETT63_RS08630	COG0366	Alpha amylase catalytic
ETT63_RS08635	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT63_RS08635	COG1263	PTS System
ETT63_RS08640	COG2188	Transcriptional regulator
ETT63_RS08655	COG2514	catechol 2,3-dioxygenase activity
ETT63_RS08665	COG0602	queuosine metabolic process
ETT63_RS08680	COG1328	CTP reductase activity
ETT63_RS08705	COG1393	Belongs to the ArsC family
ETT63_RS08720	COG0519	Catalyzes the synthesis of GMP from XMP
ETT63_RS08730	COG2814	Major facilitator Superfamily
ETT63_RS08740	COG0582	viral genome integration into host DNA
ETT63_RS08770	COG3617	BRO family, N-terminal domain
ETT63_RS08895	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT63_RS08900	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT63_RS08905	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT63_RS08990	COG1511	domain protein
ETT63_RS09010	COG0305	Participates in initiation and elongation during chromosome replication
ETT63_RS09040	COG1760	l-serine dehydratase
ETT63_RS09045	COG1760	l-serine dehydratase
ETT63_RS09050	COG0741	lytic transglycosylase activity
ETT63_RS09055	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETT63_RS09070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETT63_RS09080	COG0612	Peptidase, M16
ETT63_RS09100	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ETT63_RS09120	COG0516	GMP reductase activity
ETT63_RS09120	COG0517	IMP dehydrogenase activity
ETT63_RS09130	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT63_RS09135	COG0488	(ABC) transporter
ETT63_RS09170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETT63_RS09175	COG1475	DNA binding