locus-tag	class	description
ETT49_RS00010	COG0592	DNA-directed DNA polymerase activity
ETT49_RS00020	COG0012	GTP binding
ETT49_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETT49_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ETT49_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETT49_RS00065	COG0531	amino acid
ETT49_RS00245	COG3942	CHAP domain
ETT49_RS00265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETT49_RS00275	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ETT49_RS00290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETT49_RS00310	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETT49_RS00325	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ETT49_RS00340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETT49_RS00355	COG1012	belongs to the aldehyde dehydrogenase family
ETT49_RS00355	COG1454	alcohol dehydrogenase
ETT49_RS00360	COG1064	alcohol dehydrogenase
ETT49_RS00365	COG0534	Mate efflux family protein
ETT49_RS00475	COG0201	protein transport
ETT49_RS00620	COG1121	(ABC) transporter
ETT49_RS00625	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETT49_RS00640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT49_RS00660	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETT49_RS00665	COG1459	type II secretion system
ETT49_RS00670	COG4537	Required for transformation and DNA binding
ETT49_RS00710	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETT49_RS00715	COG1363	Peptidase, m42
ETT49_RS00730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT49_RS00735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETT49_RS00745	COG1428	Deoxynucleoside kinase
ETT49_RS00750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETT49_RS00780	COG4509	Sortase family
ETT49_RS00805	COG2031	fatty acid transporter
ETT49_RS00820	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETT49_RS00835	COG0251	oxidation-reduction process
ETT49_RS00850	COG1269	ATP hydrolysis coupled proton transport
ETT49_RS00855	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETT49_RS00865	COG1527	subunit (C
ETT49_RS00870	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
ETT49_RS00905	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT49_RS00945	COG0626	cystathionine gamma-synthase activity
ETT49_RS00975	COG3623	hexulose-6-phosphate isomerase
ETT49_RS01000	COG3448	diguanylate cyclase activity
ETT49_RS01000	COG4175	Glycine betaine
ETT49_RS01010	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT49_RS01010	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETT49_RS01045	COG1268	BioY protein
ETT49_RS01050	COG1234	tRNA 3'-trailer cleavage
ETT49_RS01085	COG0705	Rhomboid family
ETT49_RS01085	COG0457	Tetratricopeptide repeat
ETT49_RS01105	COG1132	(ABC) transporter
ETT49_RS01110	COG1132	(ABC) transporter
ETT49_RS01120	COG0756	dUTP diphosphatase activity
ETT49_RS01145	COG3290	protein histidine kinase activity
ETT49_RS01170	COG1847	R3H domain protein
ETT49_RS01190	COG1175	transmembrane transport
ETT49_RS01195	COG0395	ABC-type sugar transport system, permease component
ETT49_RS01210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETT49_RS01225	COG0084	hydrolase, TatD family'
ETT49_RS01250	COG1564	THIamine pyrophosphokinase
ETT49_RS01265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETT49_RS01290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETT49_RS01305	COG0765	amino acid transport
ETT49_RS01325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETT49_RS01335	COG0719	Fe-S assembly protein
ETT49_RS01340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETT49_RS01355	COG1686	Belongs to the peptidase S11 family
ETT49_RS01360	COG1686	Belongs to the peptidase S11 family
ETT49_RS01365	COG4166	transmembrane transport
ETT49_RS01370	COG0601	transmembrane transport
ETT49_RS01375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETT49_RS01380	COG0444	Belongs to the ABC transporter superfamily
ETT49_RS01435	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ETT49_RS01440	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ETT49_RS01445	COG1534	Rna-binding protein
ETT49_RS01455	COG1713	HD superfamily hydrolase involved in NAD metabolism
ETT49_RS01460	COG0799	negative regulation of ribosome biogenesis
ETT49_RS01465	COG2226	methyltransferase
ETT49_RS01485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT49_RS01490	COG1464	Belongs to the NlpA lipoprotein family
ETT49_RS01505	COG1114	Component of the transport system for branched-chain amino acids
ETT49_RS01515	COG0569	domain protein
ETT49_RS01520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETT49_RS01530	COG1704	LemA family
ETT49_RS01545	COG0745	RESPONSE REGULATOR receiver
ETT49_RS01565	COG1484	DNA-dependent DNA replication
ETT49_RS01575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETT49_RS01595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ETT49_RS01610	COG1254	Belongs to the acylphosphatase family
ETT49_RS01615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT49_RS01670	COG1187	pseudouridine synthase activity
ETT49_RS01685	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ETT49_RS01690	COG0671	phosphoesterase, PA-phosphatase related
ETT49_RS01695	COG1242	4 iron, 4 sulfur cluster binding
ETT49_RS01700	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ETT49_RS01705	COG1253	flavin adenine dinucleotide binding
ETT49_RS01710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT49_RS01725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT49_RS01730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ETT49_RS01735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETT49_RS01740	COG1120	ATPase activity
ETT49_RS01750	COG2244	polysaccharide biosynthetic process
ETT49_RS01785	COG0470	DNA polymerase III
ETT49_RS01810	COG1393	Belongs to the ArsC family
ETT49_RS01815	COG0708	Exodeoxyribonuclease III
ETT49_RS01825	COG1304	FMN binding
ETT49_RS01890	COG1028	Short-chain dehydrogenase reductase Sdr
ETT49_RS01895	COG0673	inositol 2-dehydrogenase activity
ETT49_RS01910	COG0494	nUDIX hydrolase
ETT49_RS01920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETT49_RS02010	COG1702	phosphate starvation-inducible protein PhoH
ETT49_RS02015	COG1573	uracil-dna glycosylase
ETT49_RS02025	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ETT49_RS02050	COG2274	protein secretion by the type I secretion system
ETT49_RS02055	COG2274	protein secretion by the type I secretion system
ETT49_RS02060	COG2274	protein secretion by the type I secretion system
ETT49_RS02090	COG2801	Transposase and inactivated derivatives
ETT49_RS02095	COG2801	Transposase and inactivated derivatives
ETT49_RS02105	COG3279	Response regulator of the LytR AlgR family
ETT49_RS02125	COG2274	protein secretion by the type I secretion system
ETT49_RS02225	COG0433	COG0433 Predicted ATPase
ETT49_RS02230	COG2814	Major facilitator Superfamily
ETT49_RS02245	COG0557	exoribonuclease II activity
ETT49_RS02275	COG0463	Glycosyl transferase, family 2
ETT49_RS02285	COG0778	Nitroreductase
ETT49_RS02290	COG0006	proline dipeptidase activity
ETT49_RS02295	COG1609	Transcriptional regulator
ETT49_RS02305	COG0438	transferase activity, transferring glycosyl groups
ETT49_RS02315	COG4555	ABC transporter
ETT49_RS02335	COG0183	Belongs to the thiolase family
ETT49_RS02350	COG0745	RESPONSE REGULATOR receiver
ETT49_RS02355	COG5002	protein histidine kinase activity
ETT49_RS02360	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETT49_RS02370	COG1196	nuclear chromosome segregation
ETT49_RS02385	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETT49_RS02490	COG0561	phosphatase activity
ETT49_RS02495	COG0561	phosphatase activity
ETT49_RS02500	COG0552	protein localization to endoplasmic reticulum
ETT49_RS02505	COG0477	Major facilitator Superfamily
ETT49_RS02510	COG3711	transcriptional antiterminator
ETT49_RS02515	COG1263	PTS System
ETT49_RS02515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS02515	COG2190	(PTS) system
ETT49_RS02525	COG3689	TIGRFAM TIGR03943 family protein
ETT49_RS02530	COG0701	Predicted permease
ETT49_RS02540	COG2183	response to ionizing radiation
ETT49_RS02585	COG0826	peptidase U32
ETT49_RS02590	COG4443	Transcriptional Coactivator p15 (PC4)
ETT49_RS02635	COG0386	Belongs to the glutathione peroxidase family
ETT49_RS02640	COG1164	Oligoendopeptidase f
ETT49_RS02650	COG0772	Belongs to the SEDS family
ETT49_RS02685	COG1078	dGTPase activity
ETT49_RS02700	COG1609	Transcriptional regulator
ETT49_RS02710	COG3716	PTS system mannose fructose sorbose family IID component
ETT49_RS02715	COG3715	PTS system
ETT49_RS02720	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS02730	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS02730	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETT49_RS02735	COG1028	Short-chain dehydrogenase reductase Sdr
ETT49_RS02760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ETT49_RS02770	COG2884	Cell division ATP-binding protein ftsE
ETT49_RS02775	COG2177	Part of the ABC transporter FtsEX involved in
ETT49_RS02790	COG1199	ATP-dependent helicase activity
ETT49_RS02790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ETT49_RS02795	COG0436	Aminotransferase
ETT49_RS02830	COG2188	Transcriptional regulator
ETT49_RS02835	COG2222	sugar isomerase
ETT49_RS02845	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ETT49_RS02850	COG0716	FMN binding
ETT49_RS02860	COG0038	chloride channel
ETT49_RS02965	COG1131	(ABC) transporter
ETT49_RS02990	COG4708	membrane
ETT49_RS03000	COG1597	lipid kinase activity
ETT49_RS03090	COG0577	efflux transmembrane transporter activity
ETT49_RS03100	COG2321	neutral zinc metallopeptidase
ETT49_RS03115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT49_RS03125	COG1970	mechanosensitive ion channel activity
ETT49_RS03130	COG0358	DNA primase activity
ETT49_RS03135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETT49_RS03140	COG2151	metal-sulfur cluster biosynthetic enzyme
ETT49_RS03185	COG1216	Glycosyl transferase, family 2
ETT49_RS03245	COG1368	sulfuric ester hydrolase activity
ETT49_RS03250	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETT49_RS03270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETT49_RS03275	COG0285	dihydrofolate synthase activity
ETT49_RS03285	COG1104	cysteine desulfurase activity
ETT49_RS03310	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETT49_RS03315	COG0583	DNA-binding transcription factor activity
ETT49_RS03325	COG0564	pseudouridine synthase activity
ETT49_RS03360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETT49_RS03365	COG1136	(ABC) transporter
ETT49_RS03370	COG0577	efflux transmembrane transporter activity
ETT49_RS03375	COG0584	glycerophosphoryl diester phosphodiesterase
ETT49_RS03385	COG1837	Belongs to the UPF0109 family
ETT49_RS03435	COG1349	DNA-binding transcription factor activity
ETT49_RS03440	COG1105	Belongs to the carbohydrate kinase PfkB family
ETT49_RS03445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETT49_RS03445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT49_RS03445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETT49_RS03450	COG1388	LysM domain
ETT49_RS03450	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT49_RS03455	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT49_RS03455	COG1388	LysM domain
ETT49_RS03480	COG0105	UTP biosynthetic process
ETT49_RS03500	COG0488	(ABC) transporter
ETT49_RS03510	COG0242	peptide deformylase activity
ETT49_RS03515	COG0737	Belongs to the 5'-nucleotidase family
ETT49_RS03520	COG2357	RelA SpoT domain protein
ETT49_RS03525	COG0745	RESPONSE REGULATOR receiver
ETT49_RS03560	COG3425	synthase
ETT49_RS03570	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETT49_RS03630	COG0583	DNA-binding transcription factor activity
ETT49_RS03660	COG0765	amino acid transport
ETT49_RS03680	COG0187	DNA topoisomerase II activity
ETT49_RS03690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ETT49_RS03710	COG0539	negative regulation of cytoplasmic translation
ETT49_RS03755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETT49_RS03760	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ETT49_RS03770	COG0300	oxidoreductase activity
ETT49_RS03775	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETT49_RS03775	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETT49_RS03790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETT49_RS03795	COG2384	SAM-dependent methyltransferase
ETT49_RS03805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETT49_RS03810	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ETT49_RS03820	COG1088	dTDP-glucose 4,6-dehydratase activity
ETT49_RS03825	COG1051	belongs to the nudix hydrolase family
ETT49_RS03830	COG0628	permease
ETT49_RS03835	COG0457	Tetratricopeptide repeat
ETT49_RS03840	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ETT49_RS03860	COG1129	ABC transporter
ETT49_RS03880	COG0488	(ABC) transporter
ETT49_RS03885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ETT49_RS03890	COG0022	dehydrogenase e1 component
ETT49_RS03890	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT49_RS03895	COG0508	dehydrogenase complex catalyzes the overall conversion of
ETT49_RS03915	COG5492	domain, Protein
ETT49_RS03920	COG0095	Lipoate-protein ligase
ETT49_RS03925	COG3442	glutamine amidotransferase
ETT49_RS03930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT49_RS03935	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ETT49_RS03955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETT49_RS03965	COG0647	UMP catabolic process
ETT49_RS03985	COG1518	maintenance of DNA repeat elements
ETT49_RS03990	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ETT49_RS04005	COG0105	UTP biosynthetic process
ETT49_RS04040	COG3715	PTS system
ETT49_RS04045	COG3716	PTS system mannose fructose sorbose family IID component
ETT49_RS04050	COG2972	Histidine kinase
ETT49_RS04055	COG4753	response regulator
ETT49_RS04055	COG2207	Transcriptional regulator
ETT49_RS04065	COG1012	belongs to the aldehyde dehydrogenase family
ETT49_RS04080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT49_RS04110	COG0285	dihydrofolate synthase activity
ETT49_RS04145	COG1176	ABC-type spermidine putrescine transport system, permease component I
ETT49_RS04150	COG1177	transmembrane transport
ETT49_RS04160	COG4565	transcriptional regulatory protein
ETT49_RS04165	COG3290	protein histidine kinase activity
ETT49_RS04170	COG3493	citrate carrier protein
ETT49_RS04185	COG3700	Belongs to the class B bacterial acid phosphatase family
ETT49_RS04190	COG0038	chloride channel
ETT49_RS04200	COG0628	permease
ETT49_RS04210	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ETT49_RS04225	COG1104	cysteine desulfurase activity
ETT49_RS04240	COG2357	RelA SpoT domain protein
ETT49_RS04250	COG0564	pseudouridine synthase activity
ETT49_RS04255	COG0280	phosphate acetyltransferase
ETT49_RS04260	COG4221	oxidoreductase activity
ETT49_RS04275	COG1174	glycine betaine transport
ETT49_RS04295	COG2233	PERMEase
ETT49_RS04320	COG2890	protein-(glutamine-N5) methyltransferase activity
ETT49_RS04350	COG1132	(ABC) transporter
ETT49_RS04355	COG1132	(ABC) transporter
ETT49_RS04375	COG3764	Sortase (surface protein transpeptidase)
ETT49_RS04380	COG0346	lactoylglutathione lyase activity
ETT49_RS04400	COG1272	protein, Hemolysin III
ETT49_RS04420	COG0758	DNA mediated transformation
ETT49_RS04425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETT49_RS04445	COG0511	ligase activity, forming carbon-carbon bonds
ETT49_RS04450	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT49_RS04465	COG2851	Citrate transporter
ETT49_RS04475	COG0511	ligase activity, forming carbon-carbon bonds
ETT49_RS04480	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ETT49_RS04510	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ETT49_RS04530	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETT49_RS04540	COG2188	Transcriptional regulator
ETT49_RS04560	COG0488	(ABC) transporter
ETT49_RS04570	COG0352	thiamine-phosphate diphosphorylase activity
ETT49_RS04570	COG0351	phosphomethylpyrimidine kinase
ETT49_RS04575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ETT49_RS04580	COG1328	CTP reductase activity
ETT49_RS04580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETT49_RS04585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETT49_RS04615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ETT49_RS04635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETT49_RS04640	COG4684	Psort location CytoplasmicMembrane, score
ETT49_RS04645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT49_RS04650	COG1079	Belongs to the binding-protein-dependent transport system permease family
ETT49_RS04655	COG4603	Belongs to the binding-protein-dependent transport system permease family
ETT49_RS04660	COG3845	ABC transporter
ETT49_RS04665	COG1744	ABC transporter substrate-binding protein PnrA-like
ETT49_RS04670	COG0295	cytidine deaminase activity
ETT49_RS04675	COG2813	Specifically methylates the guanine in position
ETT49_RS04690	COG5002	protein histidine kinase activity
ETT49_RS04695	COG0745	RESPONSE REGULATOR receiver
ETT49_RS04710	COG0704	Plays a role in the regulation of phosphate uptake
ETT49_RS04725	COG0581	inorganic phosphate transmembrane transporter activity
ETT49_RS04730	COG0573	inorganic phosphate transmembrane transporter activity
ETT49_RS04740	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ETT49_RS04740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT49_RS04745	COG0483	inositol monophosphate 1-phosphatase activity
ETT49_RS04760	COG0196	riboflavin kinase activity
ETT49_RS04790	COG1136	(ABC) transporter
ETT49_RS04790	COG4591	ABC-type transport system involved in lipoprotein release permease component
ETT49_RS04840	COG1115	amino acid carrier protein
ETT49_RS04845	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ETT49_RS04855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT49_RS04860	COG1126	abc transporter atp-binding protein
ETT49_RS04865	COG0765	amino acid transport
ETT49_RS04870	COG2824	Alkylphosphonate utilization operon protein PhnA
ETT49_RS04885	COG0469	pyruvate kinase activity
ETT49_RS04900	COG1725	Transcriptional regulator
ETT49_RS04905	COG1131	(ABC) transporter
ETT49_RS04930	COG0058	SHG alpha-glucan phosphorylase activity
ETT49_RS04935	COG1640	4-alpha-glucanotransferase
ETT49_RS04940	COG1609	Transcriptional regulator
ETT49_RS04945	COG2182	Extracellular solute-binding protein
ETT49_RS04950	COG1175	transmembrane transport
ETT49_RS04955	COG3833	ABC-type maltose transport systems, permease component
ETT49_RS04975	COG0657	acetylesterase activity
ETT49_RS04980	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ETT49_RS04990	COG1696	Membrane protein involved in D-alanine export
ETT49_RS05010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ETT49_RS05015	COG1126	abc transporter atp-binding protein
ETT49_RS05020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT49_RS05030	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT49_RS05040	COG3711	transcriptional antiterminator
ETT49_RS05050	COG2723	6-phospho-beta-galactosidase activity
ETT49_RS05080	COG0157	Belongs to the NadC ModD family
ETT49_RS05095	COG2801	Transposase and inactivated derivatives
ETT49_RS05100	COG2801	Transposase and inactivated derivatives
ETT49_RS05105	COG2801	Transposase and inactivated derivatives
ETT49_RS05110	COG1187	pseudouridine synthase activity
ETT49_RS05120	COG2814	Major facilitator Superfamily
ETT49_RS05170	COG4109	DRTGG domain
ETT49_RS05175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ETT49_RS05200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETT49_RS05200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETT49_RS05210	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETT49_RS05215	COG1956	GAF domain-containing protein
ETT49_RS05235	COG0513	Belongs to the DEAD box helicase family
ETT49_RS05240	COG0726	polysaccharide deacetylase
ETT49_RS05260	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ETT49_RS05265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETT49_RS05300	COG1476	TRANSCRIPTIONal
ETT49_RS05315	COG4122	O-methyltransferase activity
ETT49_RS05320	COG2223	nitrite transmembrane transporter activity
ETT49_RS05335	COG1187	pseudouridine synthase activity
ETT49_RS05380	COG2333	competence protein COMEC
ETT49_RS05380	COG0658	competence protein
ETT49_RS05385	COG1596	polysaccharide export
ETT49_RS05385	COG1555	photosystem II stabilization
ETT49_RS05390	COG0204	Acyl-transferase
ETT49_RS05395	COG2890	protein-(glutamine-N5) methyltransferase activity
ETT49_RS05410	COG0513	Belongs to the DEAD box helicase family
ETT49_RS05430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ETT49_RS05450	COG2116	formate transmembrane transporter activity
ETT49_RS05460	COG1827	regulation of RNA biosynthetic process
ETT49_RS05475	COG2217	Heavy metal translocating P-type atpase
ETT49_RS05490	COG2755	lipolytic protein G-D-S-L family
ETT49_RS05505	COG0497	DNA recombination
ETT49_RS05510	COG1438	arginine binding
ETT49_RS05515	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ETT49_RS05540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETT49_RS05545	COG0415	Belongs to the DNA photolyase family
ETT49_RS05555	COG0765	amino acid transport
ETT49_RS05560	COG4703	Protein of unknown function (DUF1797)
ETT49_RS05565	COG0542	response to heat
ETT49_RS05570	COG0494	nUDIX hydrolase
ETT49_RS05585	COG3599	regulation of cell shape
ETT49_RS05590	COG2302	S4 RNA-binding domain
ETT49_RS05630	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ETT49_RS05640	COG1217	gtp-binding protein TYPA
ETT49_RS05645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETT49_RS05650	COG1940	carbohydrate kinase activity
ETT49_RS05660	COG0783	Belongs to the Dps family
ETT49_RS05675	COG4470	Protein conserved in bacteria
ETT49_RS05680	COG1609	Transcriptional regulator
ETT49_RS05685	COG3480	Lon protease (S16) C-terminal proteolytic domain
ETT49_RS05695	COG0742	ribosomal rna small subunit methyltransferase
ETT49_RS05705	COG0549	Belongs to the carbamate kinase family
ETT49_RS05710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETT49_RS05715	COG1288	antiporter activity
ETT49_RS05730	COG2235	arginine
ETT49_RS05755	COG2972	Histidine kinase
ETT49_RS05770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETT49_RS05775	COG0785	Cytochrome C biogenesis protein
ETT49_RS05785	COG0673	inositol 2-dehydrogenase activity
ETT49_RS05835	COG1605	Chorismate mutase
ETT49_RS05835	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETT49_RS05855	COG2226	methyltransferase
ETT49_RS05865	COG3250	beta-galactosidase activity
ETT49_RS05870	COG2207	Transcriptional regulator
ETT49_RS05870	COG4753	response regulator
ETT49_RS05875	COG2972	Histidine kinase
ETT49_RS05885	COG1653	transport
ETT49_RS05890	COG0395	ABC-type sugar transport system, permease component
ETT49_RS05895	COG1175	transmembrane transport
ETT49_RS05905	COG2723	6-phospho-beta-galactosidase activity
ETT49_RS05910	COG3525	Glycosyl hydrolase, family 20, catalytic domain
ETT49_RS05915	COG1609	Transcriptional regulator
ETT49_RS05925	COG0383	alpha-mannosidase activity
ETT49_RS06035	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ETT49_RS06040	COG1739	Uncharacterized protein family UPF0029
ETT49_RS06050	COG1098	S1 RNA binding domain
ETT49_RS06060	COG2197	response regulator
ETT49_RS06065	COG4585	Histidine kinase
ETT49_RS06075	COG2815	serine threonine protein kinase
ETT49_RS06075	COG0515	serine threonine protein kinase
ETT49_RS06085	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ETT49_RS06085	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETT49_RS06095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETT49_RS06115	COG0583	DNA-binding transcription factor activity
ETT49_RS06120	COG0183	Belongs to the thiolase family
ETT49_RS06125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ETT49_RS06140	COG2610	gluconate transmembrane transporter activity
ETT49_RS06155	COG0116	Belongs to the methyltransferase superfamily
ETT49_RS06180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT49_RS06185	COG3579	cysteine-type endopeptidase activity
ETT49_RS06195	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ETT49_RS06200	COG1113	amino acid transport
ETT49_RS06205	COG0492	ferredoxin-NADP+ reductase activity
ETT49_RS06215	COG1126	abc transporter atp-binding protein
ETT49_RS06225	COG0513	Belongs to the DEAD box helicase family
ETT49_RS06235	COG0768	penicillin binding
ETT49_RS06270	COG1131	(ABC) transporter
ETT49_RS06295	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETT49_RS06300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT49_RS06340	COG1755	Isoprenylcysteine carboxyl methyltransferase
ETT49_RS06345	COG0656	L-ascorbic acid biosynthetic process
ETT49_RS06355	COG1283	sodium-dependent phosphate transmembrane transporter activity
ETT49_RS06375	COG0561	phosphatase activity
ETT49_RS06380	COG2860	membrane
ETT49_RS06440	COG2217	Heavy metal translocating P-type atpase
ETT49_RS06470	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ETT49_RS06475	COG0195	Participates in both transcription termination and antitermination
ETT49_RS06500	COG4473	ABC transporter
ETT49_RS06505	COG1131	(ABC) transporter
ETT49_RS06510	COG0537	adenosine 5'-monophosphoramidase activity
ETT49_RS06520	COG1316	TRANSCRIPTIONal
ETT49_RS06530	COG0802	atpase or kinase
ETT49_RS06535	COG2252	PERMEase
ETT49_RS06540	COG0561	phosphatase activity
ETT49_RS06550	COG3715	PTS system
ETT49_RS06555	COG3716	PTS system mannose fructose sorbose family IID component
ETT49_RS06585	COG0439	Biotin carboxylase
ETT49_RS06600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETT49_RS06605	COG1028	Short-chain dehydrogenase reductase Sdr
ETT49_RS06610	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETT49_RS06635	COG1024	Enoyl-CoA hydratase
ETT49_RS06655	COG1420	regulation of RNA biosynthetic process
ETT49_RS06670	COG0588	phosphoglycerate mutase activity
ETT49_RS06675	COG2261	transglycosylase associated protein
ETT49_RS06710	COG1335	isochorismatase
ETT49_RS06720	COG0436	Aminotransferase
ETT49_RS06730	COG0561	phosphatase activity
ETT49_RS06735	COG0252	asparaginase activity
ETT49_RS06750	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETT49_RS06760	COG1129	ABC transporter
ETT49_RS06775	COG1132	(ABC) transporter
ETT49_RS06780	COG4988	ABC transporter
ETT49_RS06785	COG1120	ATPase activity
ETT49_RS06810	COG3942	CHAP domain
ETT49_RS06810	COG1388	LysM domain
ETT49_RS06830	COG1482	cell wall glycoprotein biosynthetic process
ETT49_RS06835	COG1940	carbohydrate kinase activity
ETT49_RS06845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS06845	COG2190	(PTS) system
ETT49_RS06845	COG1263	PTS System
ETT49_RS06850	COG1621	beta-fructofuranosidase activity
ETT49_RS06855	COG1609	Transcriptional regulator
ETT49_RS06875	COG2131	deaminase
ETT49_RS06880	COG0006	proline dipeptidase activity
ETT49_RS06920	COG1194	a g-specific adenine glycosylase
ETT49_RS06925	COG3620	sequence-specific DNA binding
ETT49_RS06930	COG3118	belongs to the thioredoxin family
ETT49_RS06960	COG0681	Belongs to the peptidase S26 family
ETT49_RS06965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETT49_RS06980	COG1882	Formate acetyltransferase
ETT49_RS06990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETT49_RS07005	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETT49_RS07015	COG2814	Major facilitator Superfamily
ETT49_RS07020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETT49_RS07045	COG0789	Transcriptional regulator
ETT49_RS07060	COG2081	HI0933 family
ETT49_RS07070	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETT49_RS07075	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ETT49_RS07095	COG0456	acetyltransferase
ETT49_RS07100	COG1214	PFAM Peptidase M22, glycoprotease
ETT49_RS07115	COG0174	glutamine synthetase
ETT49_RS07120	COG0789	Transcriptional regulator
ETT49_RS07135	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
ETT49_RS07190	COG0668	transmembrane transport
ETT49_RS07200	COG4720	Psort location CytoplasmicMembrane, score
ETT49_RS07205	COG0351	phosphomethylpyrimidine kinase
ETT49_RS07250	COG1929	Belongs to the glycerate kinase type-1 family
ETT49_RS07255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETT49_RS07285	COG0577	efflux transmembrane transporter activity
ETT49_RS07290	COG1136	(ABC) transporter
ETT49_RS07315	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT49_RS07315	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT49_RS07320	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT49_RS07370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETT49_RS07375	COG1476	TRANSCRIPTIONal
ETT49_RS07395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETT49_RS07405	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ETT49_RS07425	COG1045	serine acetyltransferase
ETT49_RS07440	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETT49_RS07455	COG3711	transcriptional antiterminator
ETT49_RS07485	COG1846	Transcriptional regulator
ETT49_RS07505	COG4589	Belongs to the CDS family
ETT49_RS07515	COG1862	Preprotein translocase
ETT49_RS07525	COG1523	belongs to the glycosyl hydrolase 13 family
ETT49_RS07540	COG3842	ATPase activity
ETT49_RS07580	COG2190	(PTS) system
ETT49_RS07580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS07580	COG1263	PTS System
ETT49_RS07585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETT49_RS07600	COG0154	amidase activity
ETT49_RS07600	COG0154	amidase activity
ETT49_RS07605	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETT49_RS07610	COG0512	Glutamine amidotransferase of anthranilate synthase
ETT49_RS07615	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ETT49_RS07645	COG0601	transmembrane transport
ETT49_RS07655	COG1122	ATPase activity
ETT49_RS07675	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETT49_RS07705	COG3711	transcriptional antiterminator
ETT49_RS07720	COG3942	CHAP domain
ETT49_RS07720	COG1705	Flagellar rod assembly protein muramidase FlgJ
ETT49_RS07725	COG2205	protein histidine kinase activity
ETT49_RS07730	COG0745	RESPONSE REGULATOR receiver
ETT49_RS07735	COG0577	efflux transmembrane transporter activity
ETT49_RS07740	COG1136	(ABC) transporter
ETT49_RS07805	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ETT49_RS07820	COG1882	Formate acetyltransferase
ETT49_RS07825	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT49_RS07830	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ETT49_RS07835	COG1447	Phosphotransferase system cellobiose-specific component IIA
ETT49_RS07840	COG2390	Transcriptional regulator
ETT49_RS07845	COG1349	DNA-binding transcription factor activity
ETT49_RS07850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ETT49_RS07870	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ETT49_RS07885	COG0564	pseudouridine synthase activity
ETT49_RS07920	COG0542	response to heat
ETT49_RS07925	COG4463	regulation of RNA biosynthetic process
ETT49_RS07940	COG0450	alkyl hydroperoxide reductase
ETT49_RS07955	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ETT49_RS07965	COG3404	Formiminotransferase-cyclodeaminase
ETT49_RS07980	COG0531	amino acid
ETT49_RS08010	COG3590	peptidase
ETT49_RS08015	COG0366	Alpha amylase catalytic
ETT49_RS08020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ETT49_RS08020	COG1263	PTS System
ETT49_RS08025	COG2188	Transcriptional regulator
ETT49_RS08035	COG1733	regulation of RNA biosynthetic process
ETT49_RS08050	COG0602	queuosine metabolic process
ETT49_RS08065	COG1328	CTP reductase activity
ETT49_RS08090	COG1393	Belongs to the ArsC family
ETT49_RS08105	COG0519	Catalyzes the synthesis of GMP from XMP
ETT49_RS08265	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT49_RS08270	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT49_RS08275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT49_RS08325	COG1511	domain protein
ETT49_RS08345	COG0305	Participates in initiation and elongation during chromosome replication
ETT49_RS08375	COG1760	l-serine dehydratase
ETT49_RS08380	COG1760	l-serine dehydratase
ETT49_RS08385	COG0741	lytic transglycosylase activity
ETT49_RS08390	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ETT49_RS08405	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETT49_RS08415	COG0612	Peptidase, M16
ETT49_RS08455	COG0517	IMP dehydrogenase activity
ETT49_RS08455	COG0516	GMP reductase activity
ETT49_RS08465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ETT49_RS08470	COG0488	(ABC) transporter
ETT49_RS08505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETT49_RS08510	COG1475	DNA binding