locus-tag	class	description
JHX98_RS00010	COG0592	DNA-directed DNA polymerase activity
JHX98_RS00020	COG0012	GTP binding
JHX98_RS00030	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHX98_RS00035	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JHX98_RS00060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHX98_RS00065	COG0531	amino acid
JHX98_RS00240	COG3942	CHAP domain
JHX98_RS00365	COG1783	phage Terminase large subunit
JHX98_RS00480	COG1388	LysM domain
JHX98_RS00480	COG0860	N-Acetylmuramoyl-L-alanine amidase
JHX98_RS00505	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHX98_RS00515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHX98_RS00530	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHX98_RS00550	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHX98_RS00555	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHX98_RS00565	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHX98_RS00585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHX98_RS00600	COG1012	belongs to the aldehyde dehydrogenase family
JHX98_RS00600	COG1454	alcohol dehydrogenase
JHX98_RS00605	COG1064	alcohol dehydrogenase
JHX98_RS00610	COG0534	Mate efflux family protein
JHX98_RS00725	COG0201	protein transport
JHX98_RS00865	COG1121	(ABC) transporter
JHX98_RS00870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHX98_RS00885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHX98_RS00905	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHX98_RS00910	COG1459	type II secretion system
JHX98_RS00915	COG4537	Required for transformation and DNA binding
JHX98_RS00955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHX98_RS00960	COG1363	Peptidase, m42
JHX98_RS00970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JHX98_RS00975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHX98_RS00985	COG1428	Deoxynucleoside kinase
JHX98_RS00990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHX98_RS01020	COG4509	Sortase family
JHX98_RS01045	COG2031	fatty acid transporter
JHX98_RS01060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JHX98_RS01075	COG0251	oxidation-reduction process
JHX98_RS01090	COG1269	ATP hydrolysis coupled proton transport
JHX98_RS01095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHX98_RS01105	COG1527	subunit (C
JHX98_RS01110	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
JHX98_RS01145	COG1744	ABC transporter substrate-binding protein PnrA-like
JHX98_RS01185	COG0626	cystathionine gamma-synthase activity
JHX98_RS01215	COG3623	hexulose-6-phosphate isomerase
JHX98_RS01235	COG3448	diguanylate cyclase activity
JHX98_RS01235	COG4175	Glycine betaine
JHX98_RS01245	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHX98_RS01245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHX98_RS01275	COG1268	BioY protein
JHX98_RS01280	COG1234	tRNA 3'-trailer cleavage
JHX98_RS01320	COG0705	Rhomboid family
JHX98_RS01320	COG0457	Tetratricopeptide repeat
JHX98_RS01340	COG1132	(ABC) transporter
JHX98_RS01345	COG1132	(ABC) transporter
JHX98_RS01355	COG0756	dUTP diphosphatase activity
JHX98_RS01380	COG3290	protein histidine kinase activity
JHX98_RS01405	COG1847	R3H domain protein
JHX98_RS01425	COG1175	transmembrane transport
JHX98_RS01430	COG0395	ABC-type sugar transport system, permease component
JHX98_RS01440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHX98_RS01455	COG0084	hydrolase, TatD family'
JHX98_RS01480	COG1564	THIamine pyrophosphokinase
JHX98_RS01495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHX98_RS01535	COG0765	amino acid transport
JHX98_RS01555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHX98_RS01565	COG0719	Fe-S assembly protein
JHX98_RS01570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHX98_RS01585	COG1686	Belongs to the peptidase S11 family
JHX98_RS01590	COG1686	Belongs to the peptidase S11 family
JHX98_RS01595	COG4166	transmembrane transport
JHX98_RS01600	COG0601	transmembrane transport
JHX98_RS01605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHX98_RS01610	COG0444	Belongs to the ABC transporter superfamily
JHX98_RS01620	COG2801	Transposase and inactivated derivatives
JHX98_RS01635	COG2801	Transposase and inactivated derivatives
JHX98_RS01680	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JHX98_RS01685	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHX98_RS01690	COG1534	Rna-binding protein
JHX98_RS01700	COG1713	HD superfamily hydrolase involved in NAD metabolism
JHX98_RS01705	COG0799	negative regulation of ribosome biogenesis
JHX98_RS01710	COG2226	methyltransferase
JHX98_RS01725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHX98_RS01730	COG1464	Belongs to the NlpA lipoprotein family
JHX98_RS01745	COG1114	Component of the transport system for branched-chain amino acids
JHX98_RS01755	COG0569	domain protein
JHX98_RS01760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHX98_RS01770	COG1704	LemA family
JHX98_RS01785	COG0745	RESPONSE REGULATOR receiver
JHX98_RS01805	COG1484	DNA-dependent DNA replication
JHX98_RS01815	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JHX98_RS01835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHX98_RS01850	COG1254	Belongs to the acylphosphatase family
JHX98_RS01855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHX98_RS01910	COG1187	pseudouridine synthase activity
JHX98_RS01925	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JHX98_RS01930	COG0671	phosphoesterase, PA-phosphatase related
JHX98_RS01935	COG1242	4 iron, 4 sulfur cluster binding
JHX98_RS01940	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JHX98_RS01945	COG1253	flavin adenine dinucleotide binding
JHX98_RS01950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHX98_RS01965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHX98_RS01970	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHX98_RS01975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHX98_RS01980	COG1120	ATPase activity
JHX98_RS01990	COG2244	polysaccharide biosynthetic process
JHX98_RS02015	COG0470	DNA polymerase III
JHX98_RS02045	COG1393	Belongs to the ArsC family
JHX98_RS02050	COG0708	Exodeoxyribonuclease III
JHX98_RS02055	COG1304	FMN binding
JHX98_RS02115	COG1028	Short-chain dehydrogenase reductase Sdr
JHX98_RS02120	COG0673	inositol 2-dehydrogenase activity
JHX98_RS02145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHX98_RS02235	COG1702	phosphate starvation-inducible protein PhoH
JHX98_RS02240	COG1573	uracil-dna glycosylase
JHX98_RS02250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHX98_RS02345	COG0433	COG0433 Predicted ATPase
JHX98_RS02350	COG2814	Major facilitator Superfamily
JHX98_RS02365	COG0557	exoribonuclease II activity
JHX98_RS02395	COG0463	Glycosyl transferase, family 2
JHX98_RS02405	COG0778	Nitroreductase
JHX98_RS02410	COG0006	proline dipeptidase activity
JHX98_RS02415	COG1609	Transcriptional regulator
JHX98_RS02425	COG0438	transferase activity, transferring glycosyl groups
JHX98_RS02435	COG4555	ABC transporter
JHX98_RS02450	COG2376	Dihydroxyacetone kinase
JHX98_RS02460	COG2376	Dihydroxyacetone kinase
JHX98_RS02465	COG1461	Dihydroxyacetone kinase
JHX98_RS02470	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
JHX98_RS02475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHX98_RS02500	COG0745	RESPONSE REGULATOR receiver
JHX98_RS02505	COG5002	protein histidine kinase activity
JHX98_RS02510	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
JHX98_RS02520	COG1196	nuclear chromosome segregation
JHX98_RS02535	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHX98_RS02625	COG4695	Portal protein
JHX98_RS02675	COG0561	phosphatase activity
JHX98_RS02680	COG0561	phosphatase activity
JHX98_RS02685	COG0552	protein localization to endoplasmic reticulum
JHX98_RS02690	COG0477	Major facilitator Superfamily
JHX98_RS02695	COG3711	transcriptional antiterminator
JHX98_RS02700	COG2190	(PTS) system
JHX98_RS02700	COG1263	PTS System
JHX98_RS02700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHX98_RS02710	COG3689	TIGRFAM TIGR03943 family protein
JHX98_RS02715	COG0701	Predicted permease
JHX98_RS02725	COG2183	response to ionizing radiation
JHX98_RS02770	COG0826	peptidase U32
JHX98_RS02775	COG4443	Transcriptional Coactivator p15 (PC4)
JHX98_RS02825	COG0386	Belongs to the glutathione peroxidase family
JHX98_RS02830	COG1164	Oligoendopeptidase f
JHX98_RS02840	COG0772	Belongs to the SEDS family
JHX98_RS02870	COG1078	dGTPase activity
JHX98_RS02885	COG1609	Transcriptional regulator
JHX98_RS02895	COG3716	PTS system mannose fructose sorbose family IID component
JHX98_RS02900	COG3715	PTS system
JHX98_RS02905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHX98_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
JHX98_RS02935	COG0800	Aldolase
JHX98_RS02940	COG0546	phosphoglycolate phosphatase activity
JHX98_RS02945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JHX98_RS02955	COG2884	Cell division ATP-binding protein ftsE
JHX98_RS02960	COG2177	Part of the ABC transporter FtsEX involved in
JHX98_RS02975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHX98_RS02975	COG1199	ATP-dependent helicase activity
JHX98_RS02980	COG0436	Aminotransferase
JHX98_RS03015	COG3620	sequence-specific DNA binding
JHX98_RS03080	COG3723	Recombinational DNA repair protein, rece pathway
JHX98_RS03160	COG1598	PFAM Uncharacterised protein family UPF0150
JHX98_RS03205	COG0740	serine-type endopeptidase activity
JHX98_RS03295	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHX98_RS03320	COG2188	Transcriptional regulator
JHX98_RS03325	COG2222	sugar isomerase
JHX98_RS03335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JHX98_RS03340	COG0716	FMN binding
JHX98_RS03350	COG0038	chloride channel
JHX98_RS03420	COG1131	(ABC) transporter
JHX98_RS03440	COG4708	membrane
JHX98_RS03450	COG1597	lipid kinase activity
JHX98_RS03535	COG0577	efflux transmembrane transporter activity
JHX98_RS03545	COG2321	neutral zinc metallopeptidase
JHX98_RS03560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHX98_RS03570	COG1970	mechanosensitive ion channel activity
JHX98_RS03575	COG0358	DNA primase activity
JHX98_RS03580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHX98_RS03585	COG2151	metal-sulfur cluster biosynthetic enzyme
JHX98_RS03630	COG1216	Glycosyl transferase, family 2
JHX98_RS03690	COG1368	sulfuric ester hydrolase activity
JHX98_RS03695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHX98_RS03715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHX98_RS03720	COG0285	dihydrofolate synthase activity
JHX98_RS03730	COG1104	cysteine desulfurase activity
JHX98_RS03755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JHX98_RS03760	COG0583	DNA-binding transcription factor activity
JHX98_RS03770	COG0564	pseudouridine synthase activity
JHX98_RS03800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHX98_RS03805	COG1136	(ABC) transporter
JHX98_RS03810	COG0577	efflux transmembrane transporter activity
JHX98_RS03815	COG0584	glycerophosphoryl diester phosphodiesterase
JHX98_RS03825	COG1837	Belongs to the UPF0109 family
JHX98_RS03875	COG1349	DNA-binding transcription factor activity
JHX98_RS03880	COG1105	Belongs to the carbohydrate kinase PfkB family
JHX98_RS03885	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHX98_RS03885	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHX98_RS03885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHX98_RS03890	COG1388	LysM domain
JHX98_RS03890	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHX98_RS03895	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHX98_RS03895	COG1388	LysM domain
JHX98_RS03935	COG0488	(ABC) transporter
JHX98_RS03940	COG0242	peptide deformylase activity
JHX98_RS03945	COG0737	Belongs to the 5'-nucleotidase family
JHX98_RS03950	COG2357	RelA SpoT domain protein
JHX98_RS03955	COG0745	RESPONSE REGULATOR receiver
JHX98_RS03990	COG3425	synthase
JHX98_RS04000	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHX98_RS04045	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JHX98_RS04060	COG0583	DNA-binding transcription factor activity
JHX98_RS04090	COG0765	amino acid transport
JHX98_RS04110	COG0187	DNA topoisomerase II activity
JHX98_RS04125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JHX98_RS04145	COG0539	negative regulation of cytoplasmic translation
JHX98_RS04190	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHX98_RS04195	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
JHX98_RS04205	COG0300	oxidoreductase activity
JHX98_RS04210	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
JHX98_RS04210	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JHX98_RS04225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHX98_RS04230	COG2384	SAM-dependent methyltransferase
JHX98_RS04240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHX98_RS04245	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JHX98_RS04255	COG1088	dTDP-glucose 4,6-dehydratase activity
JHX98_RS04260	COG1051	belongs to the nudix hydrolase family
JHX98_RS04265	COG0628	permease
JHX98_RS04270	COG0457	Tetratricopeptide repeat
JHX98_RS04275	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JHX98_RS04290	COG1129	ABC transporter
JHX98_RS04310	COG0488	(ABC) transporter
JHX98_RS04315	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JHX98_RS04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHX98_RS04320	COG0022	dehydrogenase e1 component
JHX98_RS04325	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHX98_RS04345	COG0095	Lipoate-protein ligase
JHX98_RS04350	COG3442	glutamine amidotransferase
JHX98_RS04355	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JHX98_RS04360	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JHX98_RS04380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JHX98_RS04390	COG0647	UMP catabolic process
JHX98_RS04435	COG3715	PTS system
JHX98_RS04440	COG3716	PTS system mannose fructose sorbose family IID component
JHX98_RS04445	COG2972	Histidine kinase
JHX98_RS04450	COG4753	response regulator
JHX98_RS04450	COG2207	Transcriptional regulator
JHX98_RS04460	COG1012	belongs to the aldehyde dehydrogenase family
JHX98_RS04475	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHX98_RS04510	COG0285	dihydrofolate synthase activity
JHX98_RS04530	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHX98_RS04545	COG1176	ABC-type spermidine putrescine transport system, permease component I
JHX98_RS04550	COG1177	transmembrane transport
JHX98_RS04560	COG4565	transcriptional regulatory protein
JHX98_RS04565	COG3290	protein histidine kinase activity
JHX98_RS04570	COG3493	citrate carrier protein
JHX98_RS04585	COG3700	Belongs to the class B bacterial acid phosphatase family
JHX98_RS04590	COG0038	chloride channel
JHX98_RS04610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JHX98_RS04625	COG1104	cysteine desulfurase activity
JHX98_RS04640	COG2357	RelA SpoT domain protein
JHX98_RS04650	COG0564	pseudouridine synthase activity
JHX98_RS04655	COG0280	phosphate acetyltransferase
JHX98_RS04660	COG4221	oxidoreductase activity
JHX98_RS04675	COG1174	glycine betaine transport
JHX98_RS04690	COG2233	PERMEase
JHX98_RS04715	COG2890	protein-(glutamine-N5) methyltransferase activity
JHX98_RS04745	COG1132	(ABC) transporter
JHX98_RS04750	COG1132	(ABC) transporter
JHX98_RS04770	COG3764	Sortase (surface protein transpeptidase)
JHX98_RS04775	COG0346	lactoylglutathione lyase activity
JHX98_RS04790	COG1272	protein, Hemolysin III
JHX98_RS04810	COG0758	DNA mediated transformation
JHX98_RS04815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHX98_RS04835	COG0511	ligase activity, forming carbon-carbon bonds
JHX98_RS04840	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JHX98_RS04855	COG2851	Citrate transporter
JHX98_RS04865	COG0511	ligase activity, forming carbon-carbon bonds
JHX98_RS04870	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JHX98_RS04900	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
JHX98_RS04920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHX98_RS04930	COG2188	Transcriptional regulator
JHX98_RS04950	COG0488	(ABC) transporter
JHX98_RS04960	COG0352	thiamine-phosphate diphosphorylase activity
JHX98_RS04960	COG0351	phosphomethylpyrimidine kinase
JHX98_RS04965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHX98_RS04970	COG1328	CTP reductase activity
JHX98_RS04970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHX98_RS04975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHX98_RS05005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JHX98_RS05025	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHX98_RS05030	COG4684	Psort location CytoplasmicMembrane, score
JHX98_RS05035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHX98_RS05040	COG1079	Belongs to the binding-protein-dependent transport system permease family
JHX98_RS05045	COG4603	Belongs to the binding-protein-dependent transport system permease family
JHX98_RS05050	COG3845	ABC transporter
JHX98_RS05055	COG1744	ABC transporter substrate-binding protein PnrA-like
JHX98_RS05060	COG0295	cytidine deaminase activity
JHX98_RS05065	COG2813	Specifically methylates the guanine in position
JHX98_RS05080	COG5002	protein histidine kinase activity
JHX98_RS05085	COG0745	RESPONSE REGULATOR receiver
JHX98_RS05095	COG0704	Plays a role in the regulation of phosphate uptake
JHX98_RS05110	COG0581	inorganic phosphate transmembrane transporter activity
JHX98_RS05115	COG0573	inorganic phosphate transmembrane transporter activity
JHX98_RS05125	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JHX98_RS05125	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHX98_RS05130	COG0483	inositol monophosphate 1-phosphatase activity
JHX98_RS05145	COG0196	riboflavin kinase activity
JHX98_RS05175	COG1136	(ABC) transporter
JHX98_RS05175	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHX98_RS05225	COG1115	amino acid carrier protein
JHX98_RS05230	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JHX98_RS05240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHX98_RS05245	COG1126	abc transporter atp-binding protein
JHX98_RS05250	COG0765	amino acid transport
JHX98_RS05255	COG2824	Alkylphosphonate utilization operon protein PhnA
JHX98_RS05270	COG0469	pyruvate kinase activity
JHX98_RS05285	COG1725	Transcriptional regulator
JHX98_RS05290	COG1131	(ABC) transporter
JHX98_RS05315	COG0058	SHG alpha-glucan phosphorylase activity
JHX98_RS05320	COG1640	4-alpha-glucanotransferase
JHX98_RS05325	COG1609	Transcriptional regulator
JHX98_RS05330	COG2182	Extracellular solute-binding protein
JHX98_RS05335	COG1175	transmembrane transport
JHX98_RS05340	COG3833	ABC-type maltose transport systems, permease component
JHX98_RS05350	COG0657	acetylesterase activity
JHX98_RS05355	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JHX98_RS05365	COG1696	Membrane protein involved in D-alanine export
JHX98_RS05385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHX98_RS05390	COG1126	abc transporter atp-binding protein
JHX98_RS05400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHX98_RS05410	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHX98_RS05420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHX98_RS05420	COG3711	transcriptional antiterminator
JHX98_RS05430	COG2723	6-phospho-beta-galactosidase activity
JHX98_RS05460	COG0157	Belongs to the NadC ModD family
JHX98_RS05475	COG2801	Transposase and inactivated derivatives
JHX98_RS05480	COG2801	Transposase and inactivated derivatives
JHX98_RS05485	COG1187	pseudouridine synthase activity
JHX98_RS05495	COG2814	Major facilitator Superfamily
JHX98_RS05545	COG4109	DRTGG domain
JHX98_RS05550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHX98_RS05575	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
JHX98_RS05575	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
JHX98_RS05585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JHX98_RS05590	COG1956	GAF domain-containing protein
JHX98_RS05610	COG0513	Belongs to the DEAD box helicase family
JHX98_RS05615	COG0726	polysaccharide deacetylase
JHX98_RS05635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHX98_RS05640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHX98_RS05670	COG1476	TRANSCRIPTIONal
JHX98_RS05685	COG4122	O-methyltransferase activity
JHX98_RS05690	COG2223	nitrite transmembrane transporter activity
JHX98_RS05705	COG1187	pseudouridine synthase activity
JHX98_RS05750	COG0658	competence protein
JHX98_RS05750	COG2333	competence protein COMEC
JHX98_RS05755	COG1555	photosystem II stabilization
JHX98_RS05755	COG1596	polysaccharide export
JHX98_RS05760	COG0204	Acyl-transferase
JHX98_RS05765	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JHX98_RS05780	COG0513	Belongs to the DEAD box helicase family
JHX98_RS05795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JHX98_RS05810	COG2116	formate transmembrane transporter activity
JHX98_RS05820	COG1827	regulation of RNA biosynthetic process
JHX98_RS05840	COG2217	Heavy metal translocating P-type atpase
JHX98_RS06060	COG3723	Recombinational DNA repair protein, rece pathway
JHX98_RS06105	COG1396	sequence-specific DNA binding
JHX98_RS06115	COG0582	viral genome integration into host DNA
JHX98_RS06130	COG2755	lipolytic protein G-D-S-L family
JHX98_RS06145	COG0497	DNA recombination
JHX98_RS06150	COG1438	arginine binding
JHX98_RS06155	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
JHX98_RS06180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHX98_RS06190	COG0415	Belongs to the DNA photolyase family
JHX98_RS06200	COG0765	amino acid transport
JHX98_RS06205	COG4703	Protein of unknown function (DUF1797)
JHX98_RS06210	COG0542	response to heat
JHX98_RS06215	COG0494	nUDIX hydrolase
JHX98_RS06230	COG3599	regulation of cell shape
JHX98_RS06235	COG2302	S4 RNA-binding domain
JHX98_RS06250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JHX98_RS06285	COG1217	gtp-binding protein TYPA
JHX98_RS06290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHX98_RS06295	COG1940	carbohydrate kinase activity
JHX98_RS06305	COG0783	Belongs to the Dps family
JHX98_RS06320	COG4470	Protein conserved in bacteria
JHX98_RS06325	COG1609	Transcriptional regulator
JHX98_RS06330	COG3480	Lon protease (S16) C-terminal proteolytic domain
JHX98_RS06340	COG0742	ribosomal rna small subunit methyltransferase
JHX98_RS06350	COG0549	Belongs to the carbamate kinase family
JHX98_RS06355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHX98_RS06360	COG1288	antiporter activity
JHX98_RS06400	COG2972	Histidine kinase
JHX98_RS06415	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JHX98_RS06420	COG0785	Cytochrome C biogenesis protein
JHX98_RS06430	COG0673	inositol 2-dehydrogenase activity
JHX98_RS06470	COG1605	Chorismate mutase
JHX98_RS06470	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JHX98_RS06490	COG2226	methyltransferase
JHX98_RS06500	COG3250	beta-galactosidase activity
JHX98_RS06505	COG2207	Transcriptional regulator
JHX98_RS06505	COG4753	response regulator
JHX98_RS06510	COG2972	Histidine kinase
JHX98_RS06520	COG1653	transport
JHX98_RS06525	COG0395	ABC-type sugar transport system, permease component
JHX98_RS06530	COG1175	transmembrane transport
JHX98_RS06535	COG1940	carbohydrate kinase activity
JHX98_RS06540	COG2723	6-phospho-beta-galactosidase activity
JHX98_RS06545	COG3525	Glycosyl hydrolase, family 20, catalytic domain
JHX98_RS06560	COG0383	alpha-mannosidase activity
JHX98_RS06600	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHX98_RS06605	COG4824	toxin secretion phage lysis holin
JHX98_RS06695	COG1129	ABC transporter
JHX98_RS06730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHX98_RS06745	COG0741	lytic transglycosylase activity
JHX98_RS06745	COG0791	NLP P60 protein
JHX98_RS06770	COG1132	(ABC) transporter
JHX98_RS06770	COG2375	cellular response to nickel ion
JHX98_RS06810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHX98_RS06810	COG0551	DNA topoisomerase type I activity
JHX98_RS06825	COG3103	Sh3 type 3 domain protein
JHX98_RS06825	COG1388	LysM domain
JHX98_RS06825	COG0791	NLP P60 protein
JHX98_RS07050	COG3561	AntA/AntB antirepressor
JHX98_RS07160	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JHX98_RS07165	COG1739	Uncharacterized protein family UPF0029
JHX98_RS07175	COG1098	S1 RNA binding domain
JHX98_RS07185	COG2197	response regulator
JHX98_RS07190	COG4585	Histidine kinase
JHX98_RS07200	COG0515	serine threonine protein kinase
JHX98_RS07200	COG2815	serine threonine protein kinase
JHX98_RS07210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHX98_RS07210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHX98_RS07220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHX98_RS07240	COG0583	DNA-binding transcription factor activity
JHX98_RS07245	COG0183	Belongs to the thiolase family
JHX98_RS07250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JHX98_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
JHX98_RS07265	COG2610	gluconate transmembrane transporter activity
JHX98_RS07280	COG0116	Belongs to the methyltransferase superfamily
JHX98_RS07305	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHX98_RS07310	COG3579	cysteine-type endopeptidase activity
JHX98_RS07320	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHX98_RS07325	COG1113	amino acid transport
JHX98_RS07330	COG0492	ferredoxin-NADP+ reductase activity
JHX98_RS07340	COG1126	abc transporter atp-binding protein
JHX98_RS07350	COG0513	Belongs to the DEAD box helicase family
JHX98_RS07360	COG0768	penicillin binding
JHX98_RS07400	COG1131	(ABC) transporter
JHX98_RS07425	COG0446	pyridine nucleotide-disulphide oxidoreductase
JHX98_RS07430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHX98_RS07465	COG1755	Isoprenylcysteine carboxyl methyltransferase
JHX98_RS07470	COG0656	L-ascorbic acid biosynthetic process
JHX98_RS07480	COG1283	sodium-dependent phosphate transmembrane transporter activity
JHX98_RS07500	COG0561	phosphatase activity
JHX98_RS07505	COG2860	membrane
JHX98_RS07555	COG2217	Heavy metal translocating P-type atpase
JHX98_RS07585	COG2740	Nucleic-acid-binding protein implicated in transcription termination
JHX98_RS07590	COG0195	Participates in both transcription termination and antitermination
JHX98_RS07615	COG4473	ABC transporter
JHX98_RS07620	COG1131	(ABC) transporter
JHX98_RS07625	COG0537	adenosine 5'-monophosphoramidase activity
JHX98_RS07635	COG1316	TRANSCRIPTIONal
JHX98_RS07645	COG0802	atpase or kinase
JHX98_RS07650	COG2252	PERMEase
JHX98_RS07655	COG0561	phosphatase activity
JHX98_RS07665	COG3715	PTS system
JHX98_RS07670	COG3716	PTS system mannose fructose sorbose family IID component
JHX98_RS07695	COG0439	Biotin carboxylase
JHX98_RS07710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHX98_RS07715	COG1028	Short-chain dehydrogenase reductase Sdr
JHX98_RS07720	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JHX98_RS07745	COG1024	Enoyl-CoA hydratase
JHX98_RS07780	COG0588	phosphoglycerate mutase activity
JHX98_RS07785	COG2261	transglycosylase associated protein
JHX98_RS07815	COG1335	isochorismatase
JHX98_RS07825	COG0436	Aminotransferase
JHX98_RS07835	COG0561	phosphatase activity
JHX98_RS07840	COG0252	asparaginase activity
JHX98_RS07855	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHX98_RS07860	COG1129	ABC transporter
JHX98_RS07875	COG1132	(ABC) transporter
JHX98_RS07880	COG4988	ABC transporter
JHX98_RS07910	COG3942	CHAP domain
JHX98_RS07910	COG1388	LysM domain
JHX98_RS07930	COG1482	cell wall glycoprotein biosynthetic process
JHX98_RS07935	COG1940	carbohydrate kinase activity
JHX98_RS07945	COG1263	PTS System
JHX98_RS07945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHX98_RS07945	COG2190	(PTS) system
JHX98_RS07950	COG1621	beta-fructofuranosidase activity
JHX98_RS07955	COG1609	Transcriptional regulator
JHX98_RS07975	COG2131	deaminase
JHX98_RS07980	COG0006	proline dipeptidase activity
JHX98_RS08020	COG1194	a g-specific adenine glycosylase
JHX98_RS08025	COG3620	sequence-specific DNA binding
JHX98_RS08030	COG3118	belongs to the thioredoxin family
JHX98_RS08060	COG0681	Belongs to the peptidase S26 family
JHX98_RS08065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JHX98_RS08080	COG1882	Formate acetyltransferase
JHX98_RS08085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JHX98_RS08100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHX98_RS08105	COG2814	Major facilitator Superfamily
JHX98_RS08110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHX98_RS08135	COG0789	Transcriptional regulator
JHX98_RS08150	COG2081	HI0933 family
JHX98_RS08160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHX98_RS08165	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JHX98_RS08185	COG0456	acetyltransferase
JHX98_RS08190	COG1214	PFAM Peptidase M22, glycoprotease
JHX98_RS08205	COG0174	glutamine synthetase
JHX98_RS08210	COG0789	Transcriptional regulator
JHX98_RS08225	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
JHX98_RS08280	COG0668	transmembrane transport
JHX98_RS08290	COG4720	Psort location CytoplasmicMembrane, score
JHX98_RS08295	COG0351	phosphomethylpyrimidine kinase
JHX98_RS08340	COG1929	Belongs to the glycerate kinase type-1 family
JHX98_RS08345	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JHX98_RS08370	COG0577	efflux transmembrane transporter activity
JHX98_RS08375	COG1136	(ABC) transporter
JHX98_RS08380	COG2274	protein secretion by the type I secretion system
JHX98_RS08395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHX98_RS08395	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHX98_RS08400	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHX98_RS08445	COG4974	Belongs to the 'phage' integrase family
JHX98_RS08455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHX98_RS08460	COG1476	TRANSCRIPTIONal
JHX98_RS08480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHX98_RS08490	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JHX98_RS08505	COG1045	serine acetyltransferase
JHX98_RS08520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHX98_RS08535	COG3711	transcriptional antiterminator
JHX98_RS08565	COG1846	Transcriptional regulator
JHX98_RS08585	COG4589	Belongs to the CDS family
JHX98_RS08595	COG1862	Preprotein translocase
JHX98_RS08605	COG1523	belongs to the glycosyl hydrolase 13 family
JHX98_RS08615	COG3842	ATPase activity
JHX98_RS08655	COG1263	PTS System
JHX98_RS08655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHX98_RS08655	COG2190	(PTS) system
JHX98_RS08660	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JHX98_RS08680	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHX98_RS08685	COG0512	Glutamine amidotransferase of anthranilate synthase
JHX98_RS08690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JHX98_RS08725	COG0601	transmembrane transport
JHX98_RS08735	COG1122	ATPase activity
JHX98_RS08755	COG0803	Belongs to the bacterial solute-binding protein 9 family
JHX98_RS08780	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHX98_RS08780	COG3942	CHAP domain
JHX98_RS08785	COG2205	protein histidine kinase activity
JHX98_RS08790	COG0745	RESPONSE REGULATOR receiver
JHX98_RS08795	COG0577	efflux transmembrane transporter activity
JHX98_RS08800	COG1136	(ABC) transporter
JHX98_RS08855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JHX98_RS08870	COG1882	Formate acetyltransferase
JHX98_RS08875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHX98_RS08880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHX98_RS08885	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHX98_RS08890	COG2390	Transcriptional regulator
JHX98_RS08895	COG1349	DNA-binding transcription factor activity
JHX98_RS08900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHX98_RS08915	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHX98_RS08925	COG0564	pseudouridine synthase activity
JHX98_RS08955	COG0542	response to heat
JHX98_RS08960	COG4463	regulation of RNA biosynthetic process
JHX98_RS08975	COG0450	alkyl hydroperoxide reductase
JHX98_RS08990	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JHX98_RS09000	COG3404	Formiminotransferase-cyclodeaminase
JHX98_RS09015	COG0531	amino acid
JHX98_RS09050	COG3590	peptidase
JHX98_RS09055	COG0366	Alpha amylase catalytic
JHX98_RS09060	COG1263	PTS System
JHX98_RS09060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHX98_RS09065	COG2188	Transcriptional regulator
JHX98_RS09070	COG1733	regulation of RNA biosynthetic process
JHX98_RS09075	COG2514	catechol 2,3-dioxygenase activity
JHX98_RS09085	COG0602	queuosine metabolic process
JHX98_RS09105	COG1328	CTP reductase activity
JHX98_RS09130	COG1393	Belongs to the ArsC family
JHX98_RS09145	COG0519	Catalyzes the synthesis of GMP from XMP
JHX98_RS09280	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHX98_RS09285	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHX98_RS09290	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHX98_RS09375	COG1511	domain protein
JHX98_RS09395	COG0305	Participates in initiation and elongation during chromosome replication
JHX98_RS09425	COG1760	l-serine dehydratase
JHX98_RS09430	COG1760	l-serine dehydratase
JHX98_RS09435	COG0741	lytic transglycosylase activity
JHX98_RS09440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JHX98_RS09455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHX98_RS09465	COG0612	Peptidase, M16
JHX98_RS09470	COG0612	Peptidase, M16
JHX98_RS09485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JHX98_RS09510	COG0516	GMP reductase activity
JHX98_RS09510	COG0517	IMP dehydrogenase activity
JHX98_RS09520	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHX98_RS09525	COG0488	(ABC) transporter
JHX98_RS09560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHX98_RS09565	COG1475	DNA binding