locus-tag	class	description
FY406_RS00010	COG0737	Belongs to the 5'-nucleotidase family
FY406_RS00015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY406_RS00015	COG0072	phenylalanine-tRNA ligase activity
FY406_RS00035	COG1196	nuclear chromosome segregation
FY406_RS00040	COG0571	ribonuclease III activity
FY406_RS00055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FY406_RS00060	COG5002	protein histidine kinase activity
FY406_RS00065	COG0745	RESPONSE REGULATOR receiver
FY406_RS00070	COG1126	abc transporter atp-binding protein
FY406_RS00075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS00080	COG0765	amino acid transport
FY406_RS00085	COG0765	amino acid transport
FY406_RS00100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY406_RS00110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FY406_RS00115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FY406_RS00120	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FY406_RS00125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FY406_RS00130	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY406_RS00135	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FY406_RS00140	COG0356	it plays a direct role in the translocation of protons across the membrane
FY406_RS00150	COG0058	SHG alpha-glucan phosphorylase activity
FY406_RS00155	COG0297	glycogen (starch) synthase activity
FY406_RS00160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY406_RS00165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FY406_RS00170	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FY406_RS00175	COG1523	belongs to the glycosyl hydrolase 13 family
FY406_RS00180	COG1597	lipid kinase activity
FY406_RS00185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FY406_RS00190	COG4708	membrane
FY406_RS00195	COG2246	polysaccharide biosynthetic process
FY406_RS00200	COG2197	response regulator
FY406_RS00205	COG4585	Histidine kinase
FY406_RS00215	COG1131	(ABC) transporter
FY406_RS00220	COG1295	ribonuclease BN
FY406_RS00230	COG4109	DRTGG domain
FY406_RS00235	COG0519	Catalyzes the synthesis of GMP from XMP
FY406_RS00240	COG0667	Aldo Keto reductase
FY406_RS00245	COG0655	NAD(P)H dehydrogenase (quinone) activity
FY406_RS00250	COG0058	SHG alpha-glucan phosphorylase activity
FY406_RS00255	COG1640	4-alpha-glucanotransferase
FY406_RS00260	COG1609	Transcriptional regulator
FY406_RS00270	COG1175	transmembrane transport
FY406_RS00275	COG3833	ABC-type maltose transport systems, permease component
FY406_RS00280	COG3842	ATPase activity
FY406_RS00285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FY406_RS00290	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FY406_RS00300	COG1902	pentaerythritol trinitrate reductase activity
FY406_RS00305	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FY406_RS00305	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FY406_RS00315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FY406_RS00320	COG1956	GAF domain-containing protein
FY406_RS00325	COG3340	Belongs to the peptidase S51 family
FY406_RS00340	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FY406_RS00340	COG0456	acetyltransferase
FY406_RS00350	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FY406_RS00360	COG0066	3-isopropylmalate dehydratase activity
FY406_RS00365	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FY406_RS00375	COG0473	3-isopropylmalate dehydrogenase activity
FY406_RS00390	COG0572	uridine kinase
FY406_RS00400	COG0513	Belongs to the DEAD box helicase family
FY406_RS00415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY406_RS00420	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS00435	COG0538	isocitrate dehydrogenase activity
FY406_RS00440	COG0372	Belongs to the citrate synthase family
FY406_RS00445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FY406_RS00450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FY406_RS00455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY406_RS00460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FY406_RS00465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FY406_RS00470	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY406_RS00470	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FY406_RS00480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY406_RS00480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FY406_RS00485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FY406_RS00490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FY406_RS00495	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FY406_RS00500	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FY406_RS00550	COG1131	(ABC) transporter
FY406_RS00585	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FY406_RS00595	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FY406_RS00600	COG4122	O-methyltransferase activity
FY406_RS00605	COG0546	phosphoglycolate phosphatase activity
FY406_RS00630	COG0363	glucosamine-6-phosphate deaminase activity
FY406_RS00640	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FY406_RS00660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FY406_RS00675	COG2333	competence protein COMEC
FY406_RS00675	COG0658	competence protein
FY406_RS00680	COG1596	polysaccharide export
FY406_RS00680	COG1555	photosystem II stabilization
FY406_RS00685	COG0204	Acyl-transferase
FY406_RS00695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FY406_RS00715	COG0513	Belongs to the DEAD box helicase family
FY406_RS00735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FY406_RS00750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY406_RS00760	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY406_RS00765	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FY406_RS00770	COG0768	penicillin binding
FY406_RS00775	COG0588	phosphoglycerate mutase activity
FY406_RS00780	COG2076	Multidrug Resistance protein
FY406_RS00785	COG2217	Heavy metal translocating P-type atpase
FY406_RS00795	COG0167	dihydroorotate dehydrogenase activity
FY406_RS00810	COG0776	regulation of translation
FY406_RS00820	COG2755	lipolytic protein G-D-S-L family
FY406_RS00830	COG0497	DNA recombination
FY406_RS00835	COG1438	arginine binding
FY406_RS00840	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FY406_RS00850	COG1722	exodeoxyribonuclease VII activity
FY406_RS00855	COG1570	exodeoxyribonuclease VII activity
FY406_RS00860	COG3275	phosphorelay sensor kinase activity
FY406_RS00865	COG3279	Response regulator of the LytR AlgR family
FY406_RS00875	COG1346	cytolysis
FY406_RS00880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FY406_RS00885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FY406_RS00905	COG1126	abc transporter atp-binding protein
FY406_RS00910	COG0765	amino acid transport
FY406_RS00915	COG4703	Protein of unknown function (DUF1797)
FY406_RS00920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FY406_RS00925	COG0542	response to heat
FY406_RS00930	COG0494	nUDIX hydrolase
FY406_RS00940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FY406_RS00945	COG3599	regulation of cell shape
FY406_RS00960	COG1799	cell septum assembly
FY406_RS00965	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FY406_RS00985	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FY406_RS00990	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FY406_RS01000	COG3620	sequence-specific DNA binding
FY406_RS01010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FY406_RS01015	COG1882	Formate acetyltransferase
FY406_RS01025	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FY406_RS01040	COG2936	dipeptidyl-peptidase activity
FY406_RS01075	COG1674	ftsk spoiiie
FY406_RS01095	COG0582	viral genome integration into host DNA
FY406_RS01100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FY406_RS01115	COG2081	HI0933 family
FY406_RS01125	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FY406_RS01135	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FY406_RS01140	COG0698	ribose 5-phosphate isomerase
FY406_RS01145	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY406_RS01155	COG2190	(PTS) system
FY406_RS01155	COG1263	PTS System
FY406_RS01155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS01165	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FY406_RS01175	COG1214	PFAM Peptidase M22, glycoprotease
FY406_RS01185	COG0702	epimerase
FY406_RS01190	COG0667	Aldo Keto reductase
FY406_RS01195	COG5503	Protein of unknown function (DUF1447)
FY406_RS01205	COG3942	CHAP domain
FY406_RS01210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY406_RS01215	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FY406_RS01220	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FY406_RS01225	COG1609	Transcriptional regulator
FY406_RS01230	COG0366	Alpha amylase catalytic
FY406_RS01235	COG3842	ATPase activity
FY406_RS01240	COG0366	Alpha amylase catalytic
FY406_RS01245	COG0395	ABC-type sugar transport system, permease component
FY406_RS01250	COG1175	transmembrane transport
FY406_RS01255	COG1653	transport
FY406_RS01260	COG3345	alpha-galactosidase
FY406_RS01265	COG2207	Transcriptional regulator
FY406_RS01275	COG0493	'glutamate synthase
FY406_RS01280	COG0070	glutamate synthase
FY406_RS01280	COG0067	glutamate synthase
FY406_RS01280	COG0069	glutamate synthase activity
FY406_RS01285	COG0174	glutamine synthetase
FY406_RS01290	COG0789	Transcriptional regulator
FY406_RS01300	COG0126	phosphoglycerate kinase activity
FY406_RS01305	COG0656	L-ascorbic acid biosynthetic process
FY406_RS01320	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FY406_RS01325	COG0049	tRNA binding
FY406_RS01330	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FY406_RS01345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY406_RS01360	COG1564	THIamine pyrophosphokinase
FY406_RS01370	COG1162	GTPase activity
FY406_RS01405	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FY406_RS01425	COG0084	hydrolase, TatD family'
FY406_RS01435	COG1394	ATPase activity, coupled to movement of substances
FY406_RS01440	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FY406_RS01450	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
FY406_RS01465	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FY406_RS01470	COG1269	ATP hydrolysis coupled proton transport
FY406_RS01485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FY406_RS01495	COG0706	membrane insertase activity
FY406_RS01500	COG0594	ribonuclease P activity
FY406_RS01510	COG0137	argininosuccinate synthase activity
FY406_RS01525	COG1827	regulation of RNA biosynthetic process
FY406_RS01530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FY406_RS01555	COG0756	dUTP diphosphatase activity
FY406_RS01560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FY406_RS01565	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FY406_RS01570	COG0457	Tetratricopeptide repeat
FY406_RS01570	COG0705	Rhomboid family
FY406_RS01575	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FY406_RS01580	COG1473	amidohydrolase
FY406_RS01585	COG2171	N-acyltransferase activity
FY406_RS01605	COG3732	PTS system glucitol sorbitol-specific
FY406_RS01610	COG3730	PTS system glucitol sorbitol-specific
FY406_RS01620	COG3711	transcriptional antiterminator
FY406_RS01620	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS01630	COG0166	Belongs to the GPI family
FY406_RS01650	COG1234	tRNA 3'-trailer cleavage
FY406_RS01660	COG0343	queuine tRNA-ribosyltransferase activity
FY406_RS01665	COG1832	CoA-binding protein
FY406_RS01675	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY406_RS01675	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FY406_RS01705	COG0300	oxidoreductase activity
FY406_RS01710	COG0402	S-adenosylhomocysteine deaminase activity
FY406_RS01715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FY406_RS01725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS01730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS01745	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FY406_RS01750	COG1823	symporter activity
FY406_RS01760	COG2814	Major facilitator Superfamily
FY406_RS01770	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FY406_RS01795	COG2274	protein secretion by the type I secretion system
FY406_RS01835	COG3623	hexulose-6-phosphate isomerase
FY406_RS01855	COG3037	sugar-specific permease SgaT UlaA
FY406_RS01860	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FY406_RS01870	COG3775	system Galactitol-specific IIC component
FY406_RS01875	COG3414	Phosphotransferase system galactitol-specific IIB component
FY406_RS01885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY406_RS01885	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS01885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS01900	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FY406_RS01905	COG2918	glutathione biosynthetic process
FY406_RS01905	COG1181	Belongs to the D-alanine--D-alanine ligase family
FY406_RS01910	COG0549	Belongs to the carbamate kinase family
FY406_RS01915	COG2957	Belongs to the agmatine deiminase family
FY406_RS01920	COG0531	amino acid
FY406_RS01940	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FY406_RS01945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FY406_RS01950	COG1621	beta-fructofuranosidase activity
FY406_RS01955	COG0542	response to heat
FY406_RS01960	COG4463	regulation of RNA biosynthetic process
FY406_RS01965	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FY406_RS01970	COG0052	Belongs to the universal ribosomal protein uS2 family
FY406_RS01980	COG1619	proteins homologs of microcin C7 resistance protein MccF
FY406_RS01985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY406_RS01990	COG0446	pyridine nucleotide-disulphide oxidoreductase
FY406_RS01995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY406_RS02000	COG1937	Protein conserved in bacteria
FY406_RS02010	COG2084	Dehydrogenase
FY406_RS02015	COG1929	Belongs to the glycerate kinase type-1 family
FY406_RS02020	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY406_RS02025	COG4948	Mandelate Racemase Muconate Lactonizing
FY406_RS02035	COG4948	Mandelate Racemase Muconate Lactonizing
FY406_RS02040	COG2610	gluconate transmembrane transporter activity
FY406_RS02045	COG3835	regulator
FY406_RS02050	COG0656	L-ascorbic acid biosynthetic process
FY406_RS02055	COG3590	peptidase
FY406_RS02080	COG1131	(ABC) transporter
FY406_RS02095	COG0366	Alpha amylase catalytic
FY406_RS02100	COG1263	PTS System
FY406_RS02100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS02105	COG2188	Transcriptional regulator
FY406_RS02110	COG5297	Belongs to the glycosyl hydrolase family 6
FY406_RS02120	COG1490	D-aminoacyl-tRNA deacylase activity
FY406_RS02135	COG1263	PTS System
FY406_RS02135	COG2190	(PTS) system
FY406_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS02145	COG1609	Transcriptional regulator
FY406_RS02150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FY406_RS02155	COG2264	protein methyltransferase activity
FY406_RS02170	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY406_RS02210	COG1131	(ABC) transporter
FY406_RS02225	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY406_RS02235	COG0463	Glycosyl transferase, family 2
FY406_RS02245	COG4932	domain protein
FY406_RS02245	COG1388	LysM domain
FY406_RS02250	COG1388	LysM domain
FY406_RS02250	COG4932	domain protein
FY406_RS02255	COG0428	transporter
FY406_RS02260	COG3022	response to hydroperoxide
FY406_RS02265	COG0602	queuosine metabolic process
FY406_RS02275	COG1328	CTP reductase activity
FY406_RS02285	COG3906	Belongs to the UPF0473 family
FY406_RS02290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FY406_RS02295	COG4472	Bacterial protein of unknown function (DUF965)
FY406_RS02315	COG1393	Belongs to the ArsC family
FY406_RS02320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FY406_RS02325	COG1058	Belongs to the CinA family
FY406_RS02325	COG1546	Belongs to the CinA family
FY406_RS02330	COG0519	Catalyzes the synthesis of GMP from XMP
FY406_RS02335	COG0632	four-way junction helicase activity
FY406_RS02340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FY406_RS02345	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FY406_RS02355	COG1438	arginine binding
FY406_RS02360	COG0436	Aminotransferase
FY406_RS02370	COG0549	Belongs to the carbamate kinase family
FY406_RS02400	COG0018	arginyl-trna synthetase
FY406_RS02405	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY406_RS02410	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FY406_RS02415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY406_RS02420	COG0124	histidyl-tRNA synthetase
FY406_RS02425	COG0531	amino acid
FY406_RS02430	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY406_RS02435	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FY406_RS02440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY406_RS02485	COG2140	Oxalate decarboxylase
FY406_RS02500	COG2814	Major facilitator Superfamily
FY406_RS02515	COG1028	Short-chain dehydrogenase reductase Sdr
FY406_RS02530	COG0640	Transcriptional regulator
FY406_RS02535	COG0701	Predicted permease
FY406_RS02550	COG1819	glycosyl
FY406_RS02580	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FY406_RS02595	COG1732	Glycine betaine
FY406_RS02605	COG2094	Belongs to the DNA glycosylase MPG family
FY406_RS02610	COG1012	belongs to the aldehyde dehydrogenase family
FY406_RS02615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FY406_RS02620	COG0129	dihydroxy-acid dehydratase activity
FY406_RS02625	COG2151	metal-sulfur cluster biosynthetic enzyme
FY406_RS02635	COG0561	phosphatase activity
FY406_RS02640	COG1511	domain protein
FY406_RS02650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FY406_RS02660	COG0305	Participates in initiation and elongation during chromosome replication
FY406_RS02665	COG0359	binds to the 23S rRNA
FY406_RS02675	COG0445	tRNA wobble uridine modification
FY406_RS02685	COG0482	sulfurtransferase activity
FY406_RS02690	COG0741	lytic transglycosylase activity
FY406_RS02700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FY406_RS02705	COG1122	ATPase activity
FY406_RS02710	COG1122	ATPase activity
FY406_RS02715	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FY406_RS02725	COG0612	Peptidase, M16
FY406_RS02730	COG0612	Peptidase, M16
FY406_RS02740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FY406_RS02755	COG0488	(ABC) transporter
FY406_RS02790	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FY406_RS02795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FY406_RS02800	COG1475	DNA binding
FY406_RS02805	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FY406_RS02810	COG0592	DNA-directed DNA polymerase activity
FY406_RS02830	COG0012	GTP binding
FY406_RS02835	COG0193	aminoacyl-tRNA hydrolase activity
FY406_RS02840	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FY406_RS02845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FY406_RS02865	COG0037	tRNA processing
FY406_RS02875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FY406_RS02885	COG0531	amino acid
FY406_RS02995	COG1792	Involved in formation and maintenance of cell shape
FY406_RS03005	COG3942	CHAP domain
FY406_RS03010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY406_RS03015	COG0436	Aminotransferase
FY406_RS03020	COG1381	Involved in DNA repair and RecF pathway recombination
FY406_RS03025	COG0416	fatty acid biosynthetic process
FY406_RS03030	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY406_RS03035	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FY406_RS03040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FY406_RS03050	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FY406_RS03055	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FY406_RS03070	COG1070	Carbohydrate kinase
FY406_RS03075	COG1914	H( )-stimulated, divalent metal cation uptake system
FY406_RS03080	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FY406_RS03085	COG1984	allophanate hydrolase subunit 2
FY406_RS03090	COG0439	Biotin carboxylase
FY406_RS03095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FY406_RS03130	COG0151	Belongs to the GarS family
FY406_RS03135	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FY406_RS03150	COG1794	racemase activity, acting on amino acids and derivatives
FY406_RS03170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FY406_RS03180	COG2255	four-way junction helicase activity
FY406_RS03185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FY406_RS03210	COG0534	Mate efflux family protein
FY406_RS03215	COG0051	transcription antitermination factor activity, RNA binding
FY406_RS03225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FY406_RS03235	COG0089	rRNA binding
FY406_RS03240	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FY406_RS03255	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FY406_RS03265	COG0255	Belongs to the universal ribosomal protein uL29 family
FY406_RS03275	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FY406_RS03285	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FY406_RS03290	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FY406_RS03295	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FY406_RS03305	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FY406_RS03315	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FY406_RS03320	COG1841	ribosomal large subunit assembly
FY406_RS03330	COG0201	protein transport
FY406_RS03335	COG0563	adenylate kinase activity
FY406_RS03340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FY406_RS03350	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FY406_RS03360	COG0202	RNA polymerase activity
FY406_RS03455	COG2176	DNA-directed DNA polymerase activity
FY406_RS03460	COG1846	Transcriptional regulator
FY406_RS03475	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY406_RS03480	COG0022	dehydrogenase e1 component
FY406_RS03480	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY406_RS03485	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY406_RS03495	COG0095	Lipoate-protein ligase
FY406_RS03500	COG1473	amidohydrolase
FY406_RS03510	COG0242	peptide deformylase activity
FY406_RS03515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY406_RS03525	COG1454	alcohol dehydrogenase
FY406_RS03525	COG1012	belongs to the aldehyde dehydrogenase family
FY406_RS03530	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FY406_RS03540	COG2814	Major facilitator Superfamily
FY406_RS03545	COG0640	Transcriptional regulator
FY406_RS03555	COG1185	polyribonucleotide nucleotidyltransferase activity
FY406_RS03565	COG1045	serine acetyltransferase
FY406_RS03570	COG0215	cysteine-tRNA ligase activity
FY406_RS03575	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FY406_RS03615	COG1476	TRANSCRIPTIONal
FY406_RS03620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FY406_RS03635	COG5002	protein histidine kinase activity
FY406_RS03645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS03645	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS03645	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS03650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS03655	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS03655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS03655	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS03660	COG0383	alpha-mannosidase activity
FY406_RS03665	COG1737	Transcriptional regulator
FY406_RS03670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS03670	COG1263	PTS System
FY406_RS03670	COG2190	(PTS) system
FY406_RS03675	COG2723	6-phospho-beta-galactosidase activity
FY406_RS03685	COG3976	FMN-binding domain protein
FY406_RS03685	COG0431	NADPH-dependent FMN reductase
FY406_RS03685	COG1053	succinate dehydrogenase
FY406_RS03690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FY406_RS03710	COG3830	Belongs to the UPF0237 family
FY406_RS03715	COG2848	UPF0210 protein
FY406_RS03740	COG1420	regulation of RNA biosynthetic process
FY406_RS03745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FY406_RS03750	COG0443	Heat shock 70 kDa protein
FY406_RS03755	COG0484	heat shock protein binding
FY406_RS03760	COG0101	tRNA pseudouridine synthase activity
FY406_RS03765	COG0351	phosphomethylpyrimidine kinase
FY406_RS03765	COG0352	thiamine-phosphate diphosphorylase activity
FY406_RS03770	COG4720	Psort location CytoplasmicMembrane, score
FY406_RS03775	COG4475	Protein of unknown function (DUF436)
FY406_RS03780	COG0668	transmembrane transport
FY406_RS03790	COG0544	peptidyl-prolyl cis-trans isomerase activity
FY406_RS03795	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FY406_RS03800	COG3343	RNA polymerase activity
FY406_RS03805	COG0504	CTP synthase activity
FY406_RS03820	COG0191	fructose-bisphosphate aldolase activity
FY406_RS03830	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FY406_RS03840	COG1461	Dihydroxyacetone kinase
FY406_RS03845	COG0028	Belongs to the TPP enzyme family
FY406_RS03850	COG0440	acetolactate synthase activity
FY406_RS03855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FY406_RS03860	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FY406_RS03870	COG1309	transcriptional regulator
FY406_RS03875	COG0842	Transport permease protein
FY406_RS03890	COG1126	abc transporter atp-binding protein
FY406_RS03895	COG0765	amino acid transport
FY406_RS03915	COG2226	methyltransferase
FY406_RS03920	COG1028	Short-chain dehydrogenase reductase Sdr
FY406_RS03930	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FY406_RS03950	COG1968	undecaprenyl-diphosphatase activity
FY406_RS03955	COG4862	establishment of competence for transformation
FY406_RS03960	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY406_RS03970	COG0719	Fe-S assembly protein
FY406_RS03975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FY406_RS03985	COG0719	Fe-S assembly protein
FY406_RS03995	COG2828	Protein conserved in bacteria
FY406_RS04000	COG2851	Citrate transporter
FY406_RS04005	COG0583	DNA-binding transcription factor activity
FY406_RS04020	COG4166	transmembrane transport
FY406_RS04025	COG0601	transmembrane transport
FY406_RS04030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FY406_RS04035	COG0444	Belongs to the ABC transporter superfamily
FY406_RS04040	COG4608	Belongs to the ABC transporter superfamily
FY406_RS04045	COG0800	Aldolase
FY406_RS04080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FY406_RS04090	COG1121	(ABC) transporter
FY406_RS04095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FY406_RS04100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FY406_RS04105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY406_RS04110	COG0085	RNA polymerase activity
FY406_RS04115	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FY406_RS04135	COG5002	protein histidine kinase activity
FY406_RS04135	COG3850	Histidine kinase
FY406_RS04140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FY406_RS04145	COG1459	type II secretion system
FY406_RS04150	COG4537	Required for transformation and DNA binding
FY406_RS04175	COG0827	DNA restriction-modification system
FY406_RS04180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FY406_RS04185	COG1266	CAAX protease self-immunity
FY406_RS04190	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FY406_RS04195	COG1363	Peptidase, m42
FY406_RS04205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY406_RS04210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY406_RS04225	COG4585	Histidine kinase
FY406_RS04230	COG2197	response regulator
FY406_RS04250	COG3715	PTS system
FY406_RS04255	COG3716	PTS system mannose fructose sorbose family IID component
FY406_RS04265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FY406_RS04270	COG0459	protein refolding
FY406_RS04280	COG0564	pseudouridine synthase activity
FY406_RS04285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY406_RS04305	COG4667	esterase of the alpha-beta hydrolase superfamily
FY406_RS04315	COG0495	leucyl-tRNA aminoacylation
FY406_RS04320	COG1396	sequence-specific DNA binding
FY406_RS04330	COG1131	(ABC) transporter
FY406_RS04370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS04375	COG1464	Belongs to the NlpA lipoprotein family
FY406_RS04380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FY406_RS04385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FY406_RS04395	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FY406_RS04410	COG1122	ATPase activity
FY406_RS04430	COG0357	Ribosomal RNA small subunit methyltransferase G
FY406_RS04435	COG1704	LemA family
FY406_RS04440	COG0501	Belongs to the peptidase M48B family
FY406_RS04450	COG0745	RESPONSE REGULATOR receiver
FY406_RS04455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FY406_RS04465	COG1484	DNA-dependent DNA replication
FY406_RS04470	COG1160	GTP binding
FY406_RS04505	COG5433	transposase activity
FY406_RS04510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FY406_RS04535	COG2274	protein secretion by the type I secretion system
FY406_RS04540	COG3716	PTS system mannose fructose sorbose family IID component
FY406_RS04545	COG3715	PTS system
FY406_RS04560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FY406_RS04565	COG0681	Belongs to the peptidase S26 family
FY406_RS04570	COG1039	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FY406_RS04585	COG1193	negative regulation of DNA recombination
FY406_RS04590	COG3118	belongs to the thioredoxin family
FY406_RS04605	COG0778	Nitroreductase
FY406_RS04615	COG0629	single-stranded DNA binding
FY406_RS04620	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FY406_RS04640	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FY406_RS04650	COG0006	proline dipeptidase activity
FY406_RS04655	COG2131	deaminase
FY406_RS04660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FY406_RS04670	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY406_RS04675	COG1621	beta-fructofuranosidase activity
FY406_RS04680	COG1609	Transcriptional regulator
FY406_RS04685	COG1621	beta-fructofuranosidase activity
FY406_RS04690	COG2190	(PTS) system
FY406_RS04690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS04690	COG1263	PTS System
FY406_RS04695	COG1940	carbohydrate kinase activity
FY406_RS04700	COG1482	cell wall glycoprotein biosynthetic process
FY406_RS04705	COG0653	protein targeting
FY406_RS04710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FY406_RS04715	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FY406_RS04720	COG0736	holo-[acyl-carrier-protein] synthase activity
FY406_RS04725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FY406_RS04730	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FY406_RS04740	COG0252	asparaginase activity
FY406_RS04745	COG0561	phosphatase activity
FY406_RS04755	COG1268	BioY protein
FY406_RS04760	COG0436	Aminotransferase
FY406_RS04765	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FY406_RS04770	COG1335	isochorismatase
FY406_RS04775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FY406_RS04780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY406_RS04785	COG0154	amidase activity
FY406_RS04790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FY406_RS04800	COG0697	spore germination
FY406_RS04805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FY406_RS04810	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FY406_RS04815	COG1534	Rna-binding protein
FY406_RS04820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FY406_RS04825	COG1713	HD superfamily hydrolase involved in NAD metabolism
FY406_RS04830	COG0799	negative regulation of ribosome biogenesis
FY406_RS04835	COG2226	methyltransferase
FY406_RS04845	COG3177	Filamentation induced by cAMP protein fic
FY406_RS04850	COG1323	Belongs to the UPF0348 family
FY406_RS04865	COG4115	mRNA cleavage
FY406_RS04870	COG0789	Transcriptional regulator
FY406_RS04875	COG0242	peptide deformylase activity
FY406_RS04880	COG0217	transcriptional regulatory protein
FY406_RS04890	COG1862	Preprotein translocase
FY406_RS04895	COG5433	transposase activity
FY406_RS04900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FY406_RS04905	COG4589	Belongs to the CDS family
FY406_RS04915	COG0442	prolyl-tRNA aminoacylation
FY406_RS04990	COG3557	Belongs to the UPF0374 family
FY406_RS04995	COG2137	regulation of response to DNA damage stimulus
FY406_RS05000	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY406_RS05005	COG1780	Probably involved in ribonucleotide reductase function
FY406_RS05040	COG0346	lactoylglutathione lyase activity
FY406_RS05045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY406_RS05050	COG1418	mRNA catabolic process
FY406_RS05060	COG0525	valine-tRNA ligase activity
FY406_RS05100	COG4716	Myosin-crossreactive antigen
FY406_RS05105	COG1349	DNA-binding transcription factor activity
FY406_RS05110	COG0561	phosphatase activity
FY406_RS05120	COG3711	transcriptional antiterminator
FY406_RS05150	COG0517	IMP dehydrogenase activity
FY406_RS05155	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FY406_RS05160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FY406_RS05160	COG0574	Belongs to the PEP-utilizing enzyme family
FY406_RS05165	COG0742	ribosomal rna small subunit methyltransferase
FY406_RS05170	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FY406_RS05175	COG3480	Lon protease (S16) C-terminal proteolytic domain
FY406_RS05180	COG0737	Belongs to the 5'-nucleotidase family
FY406_RS05185	COG4470	Protein conserved in bacteria
FY406_RS05190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FY406_RS05200	COG1132	(ABC) transporter
FY406_RS05205	COG1132	(ABC) transporter
FY406_RS05210	COG4978	Transcriptional regulator
FY406_RS05210	COG0789	Transcriptional regulator
FY406_RS05215	COG3804	dihydrodipicolinate reductase
FY406_RS05235	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FY406_RS05240	COG0512	Glutamine amidotransferase of anthranilate synthase
FY406_RS05245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FY406_RS05250	COG0134	indole-3-glycerol-phosphate synthase activity
FY406_RS05255	COG0135	phosphoribosylanthranilate isomerase activity
FY406_RS05260	COG0133	tryptophan synthase activity
FY406_RS05265	COG0159	tryptophan synthase activity
FY406_RS05275	COG0783	Belongs to the Dps family
FY406_RS05285	COG1940	carbohydrate kinase activity
FY406_RS05290	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FY406_RS05295	COG1217	gtp-binding protein TYPA
FY406_RS05315	COG0561	phosphatase activity
FY406_RS05325	COG2252	PERMEase
FY406_RS05330	COG0802	atpase or kinase
FY406_RS05335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FY406_RS05340	COG1316	TRANSCRIPTIONal
FY406_RS05350	COG0537	adenosine 5'-monophosphoramidase activity
FY406_RS05355	COG1131	(ABC) transporter
FY406_RS05360	COG4473	ABC transporter
FY406_RS05370	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FY406_RS05380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FY406_RS05385	COG0779	Required for maturation of 30S ribosomal subunits
FY406_RS05390	COG0195	Participates in both transcription termination and antitermination
FY406_RS05395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FY406_RS05405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FY406_RS05410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FY406_RS05445	COG0561	phosphatase activity
FY406_RS05480	COG0752	glycyl-tRNA synthetase alpha subunit
FY406_RS05485	COG0751	glycine-tRNA ligase activity
FY406_RS05490	COG4224	UPF0291 protein
FY406_RS05500	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FY406_RS05505	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FY406_RS05510	COG0275	rRNA processing
FY406_RS05520	COG0768	penicillin binding
FY406_RS05525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FY406_RS05530	COG0513	Belongs to the DEAD box helicase family
FY406_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS05550	COG1126	abc transporter atp-binding protein
FY406_RS05560	COG0492	ferredoxin-NADP+ reductase activity
FY406_RS05570	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FY406_RS05575	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FY406_RS05580	COG3579	cysteine-type endopeptidase activity
FY406_RS05585	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FY406_RS05590	COG3331	DNA recombination
FY406_RS05595	COG4474	Belongs to the UPF0398 family
FY406_RS05600	COG3599	regulation of cell shape
FY406_RS05610	COG0116	Belongs to the methyltransferase superfamily
FY406_RS05620	COG1854	S-ribosylhomocysteine lyase activity
FY406_RS05625	COG1418	mRNA catabolic process
FY406_RS05625	COG4372	Transposase
FY406_RS05630	COG0194	GDP metabolic process
FY406_RS05635	COG1758	RNA polymerase activity
FY406_RS05640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FY406_RS05645	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FY406_RS05650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY406_RS05650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FY406_RS05670	COG4585	Histidine kinase
FY406_RS05675	COG2197	response regulator
FY406_RS05685	COG1185	polyribonucleotide nucleotidyltransferase activity
FY406_RS05695	COG1739	Uncharacterized protein family UPF0029
FY406_RS05700	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FY406_RS05705	COG1040	competence protein
FY406_RS05795	COG0527	aspartate kinase activity
FY406_RS05800	COG0546	phosphoglycolate phosphatase activity
FY406_RS05805	COG1024	Enoyl-CoA hydratase
FY406_RS05810	COG1846	Transcriptional regulator
FY406_RS05815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FY406_RS05825	COG2070	2-Nitropropane dioxygenase
FY406_RS05830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FY406_RS05835	COG1028	Short-chain dehydrogenase reductase Sdr
FY406_RS05840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FY406_RS05850	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FY406_RS05855	COG0439	Biotin carboxylase
FY406_RS05880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FY406_RS05890	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FY406_RS05895	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FY406_RS05900	COG0706	membrane insertase activity
FY406_RS05905	COG1254	Belongs to the acylphosphatase family
FY406_RS05910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FY406_RS05925	COG0019	diaminopimelate decarboxylase activity
FY406_RS05930	COG3763	UPF0154 protein
FY406_RS05935	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FY406_RS05940	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FY406_RS05955	COG0582	viral genome integration into host DNA
FY406_RS05960	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FY406_RS05965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FY406_RS05970	COG1187	pseudouridine synthase activity
FY406_RS05975	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FY406_RS05980	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FY406_RS05985	COG0569	domain protein
FY406_RS06005	COG1695	Transcriptional regulator
FY406_RS06010	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FY406_RS06015	COG0671	phosphoesterase, PA-phosphatase related
FY406_RS06020	COG1230	cation diffusion facilitator family transporter
FY406_RS06025	COG1242	4 iron, 4 sulfur cluster binding
FY406_RS06030	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FY406_RS06050	COG1119	ATPase activity
FY406_RS06055	COG0628	permease
FY406_RS06060	COG1253	flavin adenine dinucleotide binding
FY406_RS06065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FY406_RS06070	COG1227	inorganic diphosphatase activity
FY406_RS06080	COG2378	regulation of single-species biofilm formation
FY406_RS06085	COG0693	protein deglycase activity
FY406_RS06105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY406_RS06110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FY406_RS06115	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FY406_RS06120	COG1120	ATPase activity
FY406_RS06125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FY406_RS06130	COG2244	polysaccharide biosynthetic process
FY406_RS06135	COG0626	cystathionine gamma-synthase activity
FY406_RS06140	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FY406_RS06150	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FY406_RS06155	COG0740	serine-type endopeptidase activity
FY406_RS06165	COG4471	UPF0298 protein
FY406_RS06175	COG0559	Belongs to the binding-protein-dependent transport system permease family
FY406_RS06200	COG0517	IMP dehydrogenase activity
FY406_RS06205	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FY406_RS06210	COG0470	DNA polymerase III
FY406_RS06215	COG1774	PSP1 C-terminal conserved region
FY406_RS06220	COG4467	Involved in initiation control of chromosome replication
FY406_RS06230	COG0004	ammonium transporteR
FY406_RS06235	COG0347	Belongs to the P(II) protein family
FY406_RS06240	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FY406_RS06250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FY406_RS06255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FY406_RS06260	COG1393	Belongs to the ArsC family
FY406_RS06265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FY406_RS06285	COG0708	Exodeoxyribonuclease III
FY406_RS06290	COG1428	Deoxynucleoside kinase
FY406_RS06300	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY406_RS06300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FY406_RS06315	COG0435	Glutathione S-transferase
FY406_RS06350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FY406_RS06360	COG1674	ftsk spoiiie
FY406_RS06365	COG0450	alkyl hydroperoxide reductase
FY406_RS06370	COG3634	alkyl hydroperoxide reductase activity
FY406_RS06380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FY406_RS06385	COG0081	regulation of translation
FY406_RS06390	COG0528	UMP kinase activity
FY406_RS06400	COG2996	Protein conserved in bacteria
FY406_RS06415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY406_RS06420	COG4479	Belongs to the UPF0346 family
FY406_RS06425	COG1702	phosphate starvation-inducible protein PhoH
FY406_RS06435	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FY406_RS06440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FY406_RS06450	COG0596	Alpha beta hydrolase
FY406_RS06460	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FY406_RS06470	COG2264	protein methyltransferase activity
FY406_RS06475	COG2814	Major facilitator Superfamily
FY406_RS06480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FY406_RS06490	COG0557	exoribonuclease II activity
FY406_RS06495	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FY406_RS06505	COG0778	Nitroreductase
FY406_RS06510	COG1940	carbohydrate kinase activity
FY406_RS06515	COG2723	6-phospho-beta-galactosidase activity
FY406_RS06525	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FY406_RS06530	COG3711	transcriptional antiterminator
FY406_RS06530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS06535	COG1447	Phosphotransferase system cellobiose-specific component IIA
FY406_RS06545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FY406_RS06575	COG1609	Transcriptional regulator
FY406_RS06590	COG0438	transferase activity, transferring glycosyl groups
FY406_RS06605	COG1395	domain, Protein
FY406_RS06630	COG0561	phosphatase activity
FY406_RS06635	COG0561	phosphatase activity
FY406_RS06640	COG0552	protein localization to endoplasmic reticulum
FY406_RS06645	COG2814	Major facilitator Superfamily
FY406_RS06650	COG3689	TIGRFAM TIGR03943 family protein
FY406_RS06655	COG0701	Predicted permease
FY406_RS06675	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FY406_RS06680	COG0583	DNA-binding transcription factor activity
FY406_RS06715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FY406_RS06725	COG2183	response to ionizing radiation
FY406_RS06730	COG3091	SprT-like family
FY406_RS06740	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FY406_RS06745	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FY406_RS06770	COG0826	peptidase U32
FY406_RS06780	COG4443	Transcriptional Coactivator p15 (PC4)
FY406_RS06785	COG1914	H( )-stimulated, divalent metal cation uptake system
FY406_RS06800	COG1846	Transcriptional regulator
FY406_RS06825	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY406_RS06825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FY406_RS06830	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FY406_RS06845	COG0588	phosphoglycerate mutase activity
FY406_RS06855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FY406_RS06865	COG5632	N-Acetylmuramoyl-L-alanine amidase
FY406_RS06865	COG4193	domain, Protein
FY406_RS06865	COG3266	domain, Protein
FY406_RS06880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY406_RS06895	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FY406_RS06900	COG0772	Belongs to the SEDS family
FY406_RS06905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FY406_RS06910	COG0149	triose-phosphate isomerase activity
FY406_RS06920	COG2348	transferase activity, transferring amino-acyl groups
FY406_RS06930	COG1078	dGTPase activity
FY406_RS06945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY406_RS06970	COG1454	alcohol dehydrogenase
FY406_RS06975	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FY406_RS06990	COG0584	glycerophosphoryl diester phosphodiesterase
FY406_RS07005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FY406_RS07015	COG2884	Cell division ATP-binding protein ftsE
FY406_RS07020	COG2177	Part of the ABC transporter FtsEX involved in
FY406_RS07075	COG4598	ABC transporter
FY406_RS07085	COG1199	ATP-dependent helicase activity
FY406_RS07085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FY406_RS07090	COG0436	Aminotransferase
FY406_RS07095	COG0017	Asparaginyl-tRNA synthetase
FY406_RS07105	COG0251	oxidation-reduction process
FY406_RS07115	COG1309	transcriptional regulator
FY406_RS07125	COG1660	Displays ATPase and GTPase activities
FY406_RS07145	COG0583	DNA-binding transcription factor activity
FY406_RS07155	COG0281	malic enzyme
FY406_RS07160	COG0679	Auxin Efflux Carrier
FY406_RS07190	COG1063	alcohol dehydrogenase
FY406_RS07205	COG0254	rRNA binding
FY406_RS07215	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FY406_RS07220	COG2153	protein acetylation
FY406_RS07225	COG0625	glutathione transferase activity
FY406_RS07230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FY406_RS07235	COG0716	FMN binding
FY406_RS07255	COG0038	chloride channel
FY406_RS07260	COG0038	chloride channel
FY406_RS07275	COG0772	Belongs to the SEDS family
FY406_RS07290	COG0187	DNA topoisomerase II activity
FY406_RS07295	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FY406_RS07305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY406_RS07310	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FY406_RS07315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FY406_RS07320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FY406_RS07325	COG0560	Phosphoserine phosphatase
FY406_RS07335	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FY406_RS07345	COG0107	imidazoleglycerol-phosphate synthase activity
FY406_RS07350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FY406_RS07360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS07360	COG3711	transcriptional antiterminator
FY406_RS07365	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS07365	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS07365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS07370	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS07440	COG0148	phosphopyruvate hydratase activity
FY406_RS07455	COG2195	Cleaves the N-terminal amino acid of tripeptides
FY406_RS07475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FY406_RS07480	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FY406_RS07485	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FY406_RS07490	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FY406_RS07495	COG1368	sulfuric ester hydrolase activity
FY406_RS07500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FY406_RS07505	COG0710	3-dehydroquinate dehydratase activity
FY406_RS07510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FY406_RS07515	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FY406_RS07520	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FY406_RS07525	COG0287	Prephenate dehydrogenase
FY406_RS07530	COG3679	Belongs to the UPF0342 family
FY406_RS07540	COG0640	Transcriptional regulator
FY406_RS07565	COG2720	vancomycin resistance protein
FY406_RS07580	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FY406_RS07585	COG0077	Prephenate dehydratase
FY406_RS07595	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FY406_RS07605	COG0454	-acetyltransferase
FY406_RS07610	COG0745	RESPONSE REGULATOR receiver
FY406_RS07625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FY406_RS07630	COG1696	Membrane protein involved in D-alanine export
FY406_RS07635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FY406_RS07640	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FY406_RS07690	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FY406_RS07700	COG0488	(ABC) transporter
FY406_RS07705	COG1126	abc transporter atp-binding protein
FY406_RS07715	COG0556	nucleotide-excision repair
FY406_RS07740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS07745	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FY406_RS07755	COG1970	mechanosensitive ion channel activity
FY406_RS07765	COG0358	DNA primase activity
FY406_RS07770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FY406_RS07775	COG2151	metal-sulfur cluster biosynthetic enzyme
FY406_RS07780	COG1091	dTDP-4-dehydrorhamnose reductase activity
FY406_RS07815	COG1368	sulfuric ester hydrolase activity
FY406_RS07825	COG0463	Glycosyl transferase, family 2
FY406_RS07835	COG3942	CHAP domain
FY406_RS07840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY406_RS07845	COG0285	dihydrofolate synthase activity
FY406_RS07855	COG1104	cysteine desulfurase activity
FY406_RS07860	COG0301	tRNA thio-modification
FY406_RS07870	COG0201	protein transport
FY406_RS07890	COG0653	protein targeting
FY406_RS07895	COG0438	transferase activity, transferring glycosyl groups
FY406_RS07920	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FY406_RS07930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FY406_RS07945	COG2096	Adenosyltransferase
FY406_RS07950	COG1454	alcohol dehydrogenase
FY406_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
FY406_RS07980	COG4302	ethanolamine ammonia-lyase activity
FY406_RS07990	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FY406_RS07995	COG1012	belongs to the aldehyde dehydrogenase family
FY406_RS07995	COG1454	alcohol dehydrogenase
FY406_RS08010	COG4869	propanediol catabolic process
FY406_RS08020	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FY406_RS08025	COG3192	ethanolamine utilization protein
FY406_RS08045	COG0583	DNA-binding transcription factor activity
FY406_RS08050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FY406_RS08055	COG0564	pseudouridine synthase activity
FY406_RS08065	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FY406_RS08070	COG0540	Belongs to the ATCase OTCase family
FY406_RS08075	COG0505	Belongs to the CarA family
FY406_RS08080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FY406_RS08090	COG1136	(ABC) transporter
FY406_RS08095	COG0577	efflux transmembrane transporter activity
FY406_RS08100	COG0228	four-way junction DNA binding
FY406_RS08105	COG1837	Belongs to the UPF0109 family
FY406_RS08110	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FY406_RS08115	COG0336	Belongs to the RNA methyltransferase TrmD family
FY406_RS08120	COG0492	ferredoxin-NADP+ reductase activity
FY406_RS08125	COG1349	DNA-binding transcription factor activity
FY406_RS08130	COG1105	Belongs to the carbohydrate kinase PfkB family
FY406_RS08135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS08135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS08135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS08140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FY406_RS08145	COG0646	methionine synthase
FY406_RS08145	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FY406_RS08170	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FY406_RS08175	COG0617	tRNA 3'-terminal CCA addition
FY406_RS08180	COG0488	(ABC) transporter
FY406_RS08195	COG1132	(ABC) transporter
FY406_RS08205	COG5263	repeat protein
FY406_RS08205	COG0366	Alpha amylase catalytic
FY406_RS08215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FY406_RS08230	COG1131	(ABC) transporter
FY406_RS08240	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FY406_RS08250	COG0720	synthase
FY406_RS08255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FY406_RS08270	COG1132	(ABC) transporter
FY406_RS08275	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FY406_RS08295	COG2357	RelA SpoT domain protein
FY406_RS08300	COG0745	RESPONSE REGULATOR receiver
FY406_RS08310	COG3759	membrane
FY406_RS08315	COG0583	DNA-binding transcription factor activity
FY406_RS08325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS08330	COG0765	amino acid transport
FY406_RS08335	COG0765	amino acid transport
FY406_RS08340	COG1126	abc transporter atp-binding protein
FY406_RS08345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS08355	COG0435	Glutathione S-transferase
FY406_RS08360	COG0435	Glutathione S-transferase
FY406_RS08375	COG1304	FMN binding
FY406_RS08380	COG1272	protein, Hemolysin III
FY406_RS08395	COG3425	synthase
FY406_RS08400	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FY406_RS08405	COG3201	nicotinamide mononucleotide transporter
FY406_RS08410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FY406_RS08420	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FY406_RS08425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FY406_RS08430	COG0833	amino acid
FY406_RS08435	COG2040	homocysteine
FY406_RS08440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FY406_RS08465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FY406_RS08470	COG0222	ribosome binding
FY406_RS08490	COG0583	DNA-binding transcription factor activity
FY406_RS08505	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FY406_RS08510	COG1063	alcohol dehydrogenase
FY406_RS08525	COG0726	polysaccharide deacetylase
FY406_RS08535	COG0083	homoserine kinase activity
FY406_RS08540	COG2962	Rard protein
FY406_RS08545	COG0285	dihydrofolate synthase activity
FY406_RS08550	COG0302	gtp cyclohydrolase
FY406_RS08570	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FY406_RS08575	COG3842	ATPase activity
FY406_RS08580	COG1176	ABC-type spermidine putrescine transport system, permease component I
FY406_RS08585	COG1177	transmembrane transport
FY406_RS08595	COG3711	transcriptional antiterminator
FY406_RS08600	COG2190	(PTS) system
FY406_RS08600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FY406_RS08600	COG1263	PTS System
FY406_RS08605	COG0519	Catalyzes the synthesis of GMP from XMP
FY406_RS08610	COG2188	Transcriptional regulator
FY406_RS08620	COG4175	Glycine betaine
FY406_RS08620	COG3448	diguanylate cyclase activity
FY406_RS08630	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FY406_RS08635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FY406_RS08655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FY406_RS08660	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FY406_RS08670	COG1104	cysteine desulfurase activity
FY406_RS08675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FY406_RS08680	COG4116	CYTH
FY406_RS08685	COG2357	RelA SpoT domain protein
FY406_RS08690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FY406_RS08695	COG0564	pseudouridine synthase activity
FY406_RS08700	COG0280	phosphate acetyltransferase
FY406_RS08710	COG1131	(ABC) transporter
FY406_RS08715	COG4221	oxidoreductase activity
FY406_RS08720	COG1442	glycosyl transferase family 8
FY406_RS08725	COG4974	Belongs to the 'phage' integrase family
FY406_RS08750	COG3052	prosthetic group binding
FY406_RS08755	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FY406_RS08760	COG0511	ligase activity, forming carbon-carbon bonds
FY406_RS08770	COG2851	Citrate transporter
FY406_RS08780	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FY406_RS08785	COG3180	Ammonia monooxygenase
FY406_RS08795	COG0642	Histidine kinase
FY406_RS08800	COG0745	RESPONSE REGULATOR receiver
FY406_RS08810	COG1136	(ABC) transporter
FY406_RS08815	COG0366	Alpha amylase catalytic
FY406_RS08815	COG5263	repeat protein
FY406_RS08820	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FY406_RS08825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FY406_RS08830	COG0758	DNA mediated transformation
FY406_RS08835	COG0110	maltose O-acetyltransferase activity
FY406_RS08865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FY406_RS08870	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FY406_RS08875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FY406_RS08880	COG4932	domain protein
FY406_RS08895	COG4977	sequence-specific DNA binding
FY406_RS08895	COG1917	Cupin 2, conserved barrel domain protein
FY406_RS08905	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FY406_RS08915	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FY406_RS08920	COG4684	Psort location CytoplasmicMembrane, score
FY406_RS08925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY406_RS08930	COG1132	(ABC) transporter
FY406_RS08935	COG1132	(ABC) transporter
FY406_RS08950	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FY406_RS08960	COG2890	protein-(glutamine-N5) methyltransferase activity
FY406_RS08965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FY406_RS08970	COG1435	thymidine kinase activity
FY406_RS08975	COG1942	4-Oxalocrotonate Tautomerase
FY406_RS08990	COG0431	NADPH-dependent FMN reductase
FY406_RS08990	COG3976	FMN-binding domain protein
FY406_RS08990	COG1053	succinate dehydrogenase
FY406_RS08995	COG0577	efflux transmembrane transporter activity
FY406_RS09000	COG1136	(ABC) transporter
FY406_RS09005	COG1174	glycine betaine transport
FY406_RS09025	COG0628	permease
FY406_RS09030	COG2723	6-phospho-beta-galactosidase activity
FY406_RS09035	COG0406	alpha-ribazole phosphatase activity
FY406_RS09050	COG0346	lactoylglutathione lyase activity
FY406_RS09070	COG0561	phosphatase activity
FY406_RS09085	COG0346	lactoylglutathione lyase activity
FY406_RS09090	COG3764	Sortase (surface protein transpeptidase)
FY406_RS09115	COG1079	Belongs to the binding-protein-dependent transport system permease family
FY406_RS09120	COG4603	Belongs to the binding-protein-dependent transport system permease family
FY406_RS09125	COG3845	ABC transporter
FY406_RS09130	COG1744	ABC transporter substrate-binding protein PnrA-like
FY406_RS09140	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FY406_RS09150	COG2813	Specifically methylates the guanine in position
FY406_RS09155	COG1072	(Pantothenic acid kinase))
FY406_RS09160	COG0268	Binds directly to 16S ribosomal RNA
FY406_RS09165	COG5002	protein histidine kinase activity
FY406_RS09170	COG0745	RESPONSE REGULATOR receiver
FY406_RS09185	COG0704	Plays a role in the regulation of phosphate uptake
FY406_RS09190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY406_RS09195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FY406_RS09200	COG0581	inorganic phosphate transmembrane transporter activity
FY406_RS09205	COG0573	inorganic phosphate transmembrane transporter activity
FY406_RS09215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FY406_RS09215	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FY406_RS09220	COG0483	inositol monophosphate 1-phosphatase activity
FY406_RS09225	COG4476	Belongs to the UPF0223 family
FY406_RS09230	COG1393	Belongs to the ArsC family
FY406_RS09235	COG0196	riboflavin kinase activity
FY406_RS09240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FY406_RS09245	COG2205	protein histidine kinase activity
FY406_RS09250	COG0745	RESPONSE REGULATOR receiver
FY406_RS09305	COG1136	(ABC) transporter
FY406_RS09315	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FY406_RS09320	COG0785	Cytochrome C biogenesis protein
FY406_RS09330	COG2873	o-acetylhomoserine
FY406_RS09335	COG0210	DNA helicase
FY406_RS09340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FY406_RS09345	COG1115	amino acid carrier protein
FY406_RS09350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FY406_RS09355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS09360	COG1126	abc transporter atp-binding protein
FY406_RS09365	COG0765	amino acid transport
FY406_RS09370	COG2824	Alkylphosphonate utilization operon protein PhnA
FY406_RS09375	COG0246	Mannitol dehydrogenase
FY406_RS09380	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS09385	COG3711	transcriptional antiterminator
FY406_RS09390	COG2213	PTS system mannitol-specific
FY406_RS09395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FY406_RS09410	COG0469	pyruvate kinase activity
FY406_RS09415	COG0205	6-phosphofructokinase activity
FY406_RS09425	COG5433	transposase activity
FY406_RS09430	COG1725	Transcriptional regulator
FY406_RS09435	COG1131	(ABC) transporter
FY406_RS09455	COG0398	Pfam SNARE associated Golgi protein
FY406_RS09465	COG1132	(ABC) transporter
FY406_RS09475	COG0539	negative regulation of cytoplasmic translation
FY406_RS09495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FY406_RS09510	COG0187	DNA topoisomerase II activity
FY406_RS09515	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FY406_RS09520	COG0737	Belongs to the 5'-nucleotidase family
FY406_RS09530	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FY406_RS09535	COG0765	amino acid transport
FY406_RS09540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FY406_RS09550	COG1881	PFAM PEBP family protein
FY406_RS09555	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FY406_RS09560	COG0284	orotidine-5'-phosphate decarboxylase activity
FY406_RS09565	COG0167	dihydroorotate dehydrogenase activity
FY406_RS09570	COG0543	2 iron, 2 sulfur cluster binding
FY406_RS09575	COG3475	LICD family
FY406_RS09580	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FY406_RS09585	COG3475	LICD family
FY406_RS09590	COG1216	Glycosyl transferase, family 2
FY406_RS09605	COG0562	UDP-galactopyranose mutase
FY406_RS09610	COG2244	polysaccharide biosynthetic process
FY406_RS09635	COG0813	purine-nucleoside phosphorylase activity
FY406_RS09655	COG2267	carboxylic ester hydrolase activity
FY406_RS09665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FY406_RS09670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FY406_RS09680	COG1573	uracil-dna glycosylase
FY406_RS09705	COG0322	excinuclease ABC activity
FY406_RS09760	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS09760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FY406_RS09760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FY406_RS09765	COG1105	Belongs to the carbohydrate kinase PfkB family
FY406_RS09775	COG0789	Transcriptional regulator
FY406_RS09805	COG0481	GTPase activity
FY406_RS09815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FY406_RS09820	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FY406_RS09840	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FY406_RS09845	COG1518	maintenance of DNA repeat elements
FY406_RS09850	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
FY406_RS09865	COG1136	(ABC) transporter
FY406_RS09865	COG0577	efflux transmembrane transporter activity
FY406_RS09875	COG0647	UMP catabolic process
FY406_RS09885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FY406_RS09895	COG2249	NAD(P)H dehydrogenase (quinone) activity
FY406_RS09900	COG0508	dehydrogenase complex catalyzes the overall conversion of
FY406_RS09905	COG0022	dehydrogenase e1 component
FY406_RS09910	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FY406_RS09920	COG0542	response to heat
FY406_RS09925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FY406_RS09935	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FY406_RS09940	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FY406_RS09945	COG3442	glutamine amidotransferase
FY406_RS09950	COG0488	(ABC) transporter
FY406_RS09960	COG1215	transferase activity, transferring glycosyl groups
FY406_RS09975	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FY406_RS09985	COG4808	Protein conserved in bacteria
FY406_RS10005	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FY406_RS10020	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FY406_RS10025	COG1113	amino acid transport
FY406_RS10030	COG3527	Alpha-acetolactate decarboxylase
FY406_RS10035	COG0028	Belongs to the TPP enzyme family
FY406_RS10045	COG0628	permease
FY406_RS10050	COG1051	belongs to the nudix hydrolase family
FY406_RS10070	COG1088	dTDP-glucose 4,6-dehydratase activity
FY406_RS10085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FY406_RS10090	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FY406_RS10100	COG2384	SAM-dependent methyltransferase
FY406_RS10110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FY406_RS10115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FY406_RS10120	COG5433	transposase activity
FY406_RS10125	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FY406_RS10125	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FY406_RS10130	COG0300	oxidoreductase activity
FY406_RS10135	COG1234	tRNA 3'-trailer cleavage
FY406_RS10140	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
FY406_RS10145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FY406_RS10150	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FY406_RS10160	COG1396	sequence-specific DNA binding
FY406_RS10170	COG0686	Belongs to the AlaDH PNT family
FY406_RS10200	COG2723	6-phospho-beta-galactosidase activity
FY406_RS10205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FY406_RS10205	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FY406_RS10210	COG1447	Phosphotransferase system cellobiose-specific component IIA
FY406_RS10215	COG3711	transcriptional antiterminator
FY406_RS10220	COG3775	system Galactitol-specific IIC component
FY406_RS10235	COG3684	Belongs to the aldolase LacD family
FY406_RS10240	COG1105	Belongs to the carbohydrate kinase PfkB family
FY406_RS10260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FY406_RS10270	COG1074	ATP-dependent DNA helicase activity
FY406_RS10275	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FY406_RS10285	COG3041	Addiction module toxin RelE StbE family
FY406_RS10295	COG2176	DNA-directed DNA polymerase activity
FY406_RS10300	COG1518	maintenance of DNA repeat elements
FY406_RS10315	COG1857	crispr-associated protein
FY406_RS10335	COG2321	neutral zinc metallopeptidase