locus-tag	class	description
I6I02_RS00020	COG4475	Protein of unknown function (DUF436)
I6I02_RS00030	COG0366	Alpha amylase catalytic
I6I02_RS00035	COG3590	peptidase
I6I02_RS00040	COG1454	alcohol dehydrogenase
I6I02_RS00040	COG1012	belongs to the aldehyde dehydrogenase family
I6I02_RS00060	COG0534	Mate efflux family protein
I6I02_RS00070	COG1461	Dihydroxyacetone kinase
I6I02_RS00075	COG0129	dihydroxy-acid dehydratase activity
I6I02_RS00080	COG0028	Belongs to the TPP enzyme family
I6I02_RS00085	COG0440	acetolactate synthase activity
I6I02_RS00100	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I02_RS00100	COG4499	WXG100 protein secretion system (Wss), protein YukC
I6I02_RS00120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
I6I02_RS00125	COG1459	type II secretion system
I6I02_RS00180	COG1266	CAAX protease self-immunity
I6I02_RS00185	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
I6I02_RS00190	COG1363	Peptidase, m42
I6I02_RS00200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
I6I02_RS00210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I6I02_RS00215	COG2391	methyltransferase activity
I6I02_RS00220	COG0425	Belongs to the sulfur carrier protein TusA family
I6I02_RS00255	COG2226	methyltransferase
I6I02_RS00260	COG0647	UMP catabolic process
I6I02_RS00275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
I6I02_RS00280	COG0705	Rhomboid family
I6I02_RS00280	COG0457	Tetratricopeptide repeat
I6I02_RS00285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
I6I02_RS00305	COG1053	succinate dehydrogenase
I6I02_RS00305	COG0431	NADPH-dependent FMN reductase
I6I02_RS00305	COG3976	FMN-binding domain protein
I6I02_RS00315	COG0756	dUTP diphosphatase activity
I6I02_RS00355	COG4166	transmembrane transport
I6I02_RS00405	COG0706	membrane insertase activity
I6I02_RS00420	COG2249	NAD(P)H dehydrogenase (quinone) activity
I6I02_RS00475	COG3118	belongs to the thioredoxin family
I6I02_RS00480	COG1832	CoA-binding protein
I6I02_RS00485	COG0084	hydrolase, TatD family'
I6I02_RS00530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
I6I02_RS00555	COG0126	phosphoglycerate kinase activity
I6I02_RS00565	COG0789	Transcriptional regulator
I6I02_RS00570	COG0174	glutamine synthetase
I6I02_RS00575	COG3942	CHAP domain
I6I02_RS00590	COG1214	PFAM Peptidase M22, glycoprotease
I6I02_RS00595	COG0456	acetyltransferase
I6I02_RS00605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
I6I02_RS00615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
I6I02_RS00620	COG0681	Belongs to the peptidase S26 family
I6I02_RS00645	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I6I02_RS00645	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
I6I02_RS00720	COG1131	(ABC) transporter
I6I02_RS00730	COG0006	proline dipeptidase activity
I6I02_RS00735	COG2131	deaminase
I6I02_RS00740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
I6I02_RS00755	COG1609	Transcriptional regulator
I6I02_RS00760	COG1621	beta-fructofuranosidase activity
I6I02_RS00765	COG1263	PTS System
I6I02_RS00765	COG2190	(PTS) system
I6I02_RS00765	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I02_RS00770	COG1940	carbohydrate kinase activity
I6I02_RS00775	COG1482	cell wall glycoprotein biosynthetic process
I6I02_RS00785	COG0653	protein targeting
I6I02_RS00790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6I02_RS00795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
I6I02_RS00810	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
I6I02_RS00830	COG3655	Transcriptional regulator
I6I02_RS00840	COG0252	asparaginase activity
I6I02_RS00845	COG0561	phosphatase activity
I6I02_RS00895	COG0443	Heat shock 70 kDa protein
I6I02_RS00905	COG1116	anion transmembrane transporter activity
I6I02_RS00945	COG1811	Na channel or pump
I6I02_RS00950	COG4152	abc transporter atp-binding protein
I6I02_RS00960	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
I6I02_RS00965	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
I6I02_RS01020	COG0768	penicillin binding
I6I02_RS01030	COG0513	Belongs to the DEAD box helicase family
I6I02_RS01040	COG0737	Belongs to the 5'-nucleotidase family
I6I02_RS01045	COG4470	Protein conserved in bacteria
I6I02_RS01065	COG1132	(ABC) transporter
I6I02_RS01070	COG1132	(ABC) transporter
I6I02_RS01095	COG2936	dipeptidyl-peptidase activity
I6I02_RS01100	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
I6I02_RS01115	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
I6I02_RS01135	COG1882	Formate acetyltransferase
I6I02_RS01150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS01160	COG1126	abc transporter atp-binding protein
I6I02_RS01175	COG0742	ribosomal rna small subunit methyltransferase
I6I02_RS01180	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
I6I02_RS01185	COG3480	Lon protease (S16) C-terminal proteolytic domain
I6I02_RS01190	COG1242	4 iron, 4 sulfur cluster binding
I6I02_RS01220	COG1119	ATPase activity
I6I02_RS01225	COG1253	flavin adenine dinucleotide binding
I6I02_RS01235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
I6I02_RS01245	COG2801	Transposase and inactivated derivatives
I6I02_RS01255	COG0589	response to stress
I6I02_RS01260	COG0436	Aminotransferase
I6I02_RS01270	COG1335	isochorismatase
I6I02_RS01285	COG2723	6-phospho-beta-galactosidase activity
I6I02_RS01290	COG1442	glycosyl transferase family 8
I6I02_RS01295	COG1216	Glycosyl transferase, family 2
I6I02_RS01295	COG1442	glycosyl transferase family 8
I6I02_RS01335	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
I6I02_RS01340	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I6I02_RS01345	COG1534	Rna-binding protein
I6I02_RS01350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
I6I02_RS01355	COG1713	HD superfamily hydrolase involved in NAD metabolism
I6I02_RS01365	COG0799	negative regulation of ribosome biogenesis
I6I02_RS01370	COG2226	methyltransferase
I6I02_RS01400	COG2801	Transposase and inactivated derivatives
I6I02_RS01430	COG0537	adenosine 5'-monophosphoramidase activity
I6I02_RS01435	COG1131	(ABC) transporter
I6I02_RS01460	COG2081	HI0933 family
I6I02_RS01470	COG2151	metal-sulfur cluster biosynthetic enzyme
I6I02_RS01480	COG2176	DNA-directed DNA polymerase activity
I6I02_RS01495	COG1136	(ABC) transporter
I6I02_RS01495	COG4591	ABC-type transport system involved in lipoprotein release permease component
I6I02_RS01530	COG5001	Diguanylate cyclase
I6I02_RS01530	COG3300	MHYT domain
I6I02_RS01555	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I6I02_RS01565	COG0287	Prephenate dehydrogenase
I6I02_RS01565	COG1605	Chorismate mutase
I6I02_RS01570	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I6I02_RS01575	COG0512	Glutamine amidotransferase of anthranilate synthase
I6I02_RS01590	COG0135	phosphoribosylanthranilate isomerase activity
I6I02_RS01595	COG0133	tryptophan synthase activity
I6I02_RS01600	COG0159	tryptophan synthase activity
I6I02_RS01615	COG2217	Heavy metal translocating P-type atpase
I6I02_RS01625	COG1181	Belongs to the D-alanine--D-alanine ligase family
I6I02_RS01630	COG0765	amino acid transport
I6I02_RS01635	COG0765	amino acid transport
I6I02_RS01640	COG1126	abc transporter atp-binding protein
I6I02_RS01645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS01665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I6I02_RS01685	COG2211	Major facilitator Superfamily
I6I02_RS01690	COG1396	sequence-specific DNA binding
I6I02_RS01710	COG0513	Belongs to the DEAD box helicase family
I6I02_RS01725	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
I6I02_RS01730	COG0726	polysaccharide deacetylase
I6I02_RS01735	COG0204	Acyl-transferase
I6I02_RS01740	COG1555	photosystem II stabilization
I6I02_RS01740	COG1596	polysaccharide export
I6I02_RS01745	COG0658	competence protein
I6I02_RS01745	COG2333	competence protein COMEC
I6I02_RS01750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
I6I02_RS01755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6I02_RS01760	COG4109	DRTGG domain
I6I02_RS01765	COG0024	Methionine aminopeptidase
I6I02_RS01775	COG4708	membrane
I6I02_RS01785	COG1597	lipid kinase activity
I6I02_RS01810	COG0708	Exodeoxyribonuclease III
I6I02_RS01825	COG3615	Tellurite resistance protein tehB
I6I02_RS01825	COG0500	methyltransferase
I6I02_RS01860	COG0285	dihydrofolate synthase activity
I6I02_RS01865	COG0531	amino acid
I6I02_RS01905	COG1176	ABC-type spermidine putrescine transport system, permease component I
I6I02_RS01910	COG1177	transmembrane transport
I6I02_RS01925	COG0346	lactoylglutathione lyase activity
I6I02_RS01945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
I6I02_RS01950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
I6I02_RS01955	COG1393	Belongs to the ArsC family
I6I02_RS01965	COG1380	Effector of murein hydrolase LrgA
I6I02_RS01970	COG1346	cytolysis
I6I02_RS01980	COG0187	DNA topoisomerase II activity
I6I02_RS01985	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
I6I02_RS01990	COG0560	Phosphoserine phosphatase
I6I02_RS02025	COG1187	pseudouridine synthase activity
I6I02_RS02045	COG1126	abc transporter atp-binding protein
I6I02_RS02050	COG0765	amino acid transport
I6I02_RS02075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS02080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS02085	COG0436	Aminotransferase
I6I02_RS02090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS02095	COG0828	Belongs to the bacterial ribosomal protein bS21 family
I6I02_RS02100	COG1970	mechanosensitive ion channel activity
I6I02_RS02105	COG0358	DNA primase activity
I6I02_RS02110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
I6I02_RS02115	COG2151	metal-sulfur cluster biosynthetic enzyme
I6I02_RS02120	COG0463	Glycosyl transferase, family 2
I6I02_RS02130	COG1091	dTDP-4-dehydrorhamnose reductase activity
I6I02_RS02140	COG1216	Glycosyl transferase, family 2
I6I02_RS02145	COG1216	Glycosyl transferase, family 2
I6I02_RS02150	COG0463	Glycosyl transferase, family 2
I6I02_RS02170	COG1216	Glycosyl transferase, family 2
I6I02_RS02170	COG1442	glycosyl transferase family 8
I6I02_RS02190	COG0463	Glycosyl transferase, family 2
I6I02_RS02215	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
I6I02_RS02230	COG1104	cysteine desulfurase activity
I6I02_RS02245	COG2357	RelA SpoT domain protein
I6I02_RS02255	COG0564	pseudouridine synthase activity
I6I02_RS02265	COG4166	transmembrane transport
I6I02_RS02270	COG4166	transmembrane transport
I6I02_RS02275	COG0601	transmembrane transport
I6I02_RS02280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
I6I02_RS02285	COG0444	Belongs to the ABC transporter superfamily
I6I02_RS02290	COG4608	Belongs to the ABC transporter superfamily
I6I02_RS02300	COG1131	(ABC) transporter
I6I02_RS02305	COG1725	Transcriptional regulator
I6I02_RS02310	COG0561	phosphatase activity
I6I02_RS02315	COG0561	phosphatase activity
I6I02_RS02320	COG0552	protein localization to endoplasmic reticulum
I6I02_RS02335	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
I6I02_RS02345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
I6I02_RS02345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I6I02_RS02355	COG0515	serine threonine protein kinase
I6I02_RS02355	COG2815	serine threonine protein kinase
I6I02_RS02360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
I6I02_RS02370	COG4585	Histidine kinase
I6I02_RS02375	COG2197	response regulator
I6I02_RS02410	COG1523	belongs to the glycosyl hydrolase 13 family
I6I02_RS02415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
I6I02_RS02420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I6I02_RS02425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
I6I02_RS02430	COG0297	glycogen (starch) synthase activity
I6I02_RS02435	COG0058	SHG alpha-glucan phosphorylase activity
I6I02_RS02460	COG1132	(ABC) transporter
I6I02_RS02465	COG1132	(ABC) transporter
I6I02_RS02505	COG3064	Membrane
I6I02_RS02515	COG0420	3'-5' exonuclease activity
I6I02_RS02520	COG0419	ATPase involved in DNA repair
I6I02_RS02525	COG1442	glycosyl transferase family 8
I6I02_RS02525	COG1216	Glycosyl transferase, family 2
I6I02_RS02550	COG0653	protein targeting
I6I02_RS02560	COG0438	transferase activity, transferring glycosyl groups
I6I02_RS02615	COG0366	Alpha amylase catalytic
I6I02_RS02615	COG5263	repeat protein
I6I02_RS02625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
I6I02_RS02630	COG0110	maltose O-acetyltransferase activity
I6I02_RS02640	COG2801	Transposase and inactivated derivatives
I6I02_RS02655	COG0477	Major facilitator Superfamily
I6I02_RS02665	COG0583	DNA-binding transcription factor activity
I6I02_RS02675	COG0281	malic enzyme
I6I02_RS02750	COG5263	repeat protein
I6I02_RS02750	COG0366	Alpha amylase catalytic
I6I02_RS02755	COG5263	repeat protein
I6I02_RS02755	COG0366	Alpha amylase catalytic
I6I02_RS02765	COG0640	Transcriptional regulator
I6I02_RS02780	COG3590	peptidase
I6I02_RS02805	COG2376	Dihydroxyacetone kinase
I6I02_RS02810	COG1461	Dihydroxyacetone kinase
I6I02_RS02815	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
I6I02_RS02845	COG1136	(ABC) transporter
I6I02_RS02850	COG0577	efflux transmembrane transporter activity
I6I02_RS02855	COG0745	RESPONSE REGULATOR receiver
I6I02_RS02860	COG5002	protein histidine kinase activity
I6I02_RS02870	COG2801	Transposase and inactivated derivatives
I6I02_RS02880	COG0366	Alpha amylase catalytic
I6I02_RS02885	COG1609	Transcriptional regulator
I6I02_RS02900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I6I02_RS02905	COG0656	L-ascorbic acid biosynthetic process
I6I02_RS02925	COG0778	Nitroreductase
I6I02_RS02930	COG0745	RESPONSE REGULATOR receiver
I6I02_RS02935	COG2205	protein histidine kinase activity
I6I02_RS02950	COG1131	(ABC) transporter
I6I02_RS02955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
I6I02_RS02965	COG1959	2 iron, 2 sulfur cluster binding
I6I02_RS02970	COG2514	catechol 2,3-dioxygenase activity
I6I02_RS02985	COG1476	TRANSCRIPTIONal
I6I02_RS02995	COG4989	oxidoreductase activity
I6I02_RS03030	COG0386	Belongs to the glutathione peroxidase family
I6I02_RS03040	COG0531	amino acid
I6I02_RS03055	COG3237	CsbD-like
I6I02_RS03070	COG1482	cell wall glycoprotein biosynthetic process
I6I02_RS03075	COG1114	Component of the transport system for branched-chain amino acids
I6I02_RS03080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I6I02_RS03080	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
I6I02_RS03085	COG0534	Mate efflux family protein
I6I02_RS03090	COG2233	PERMEase
I6I02_RS03100	COG0745	RESPONSE REGULATOR receiver
I6I02_RS03110	COG1136	(ABC) transporter
I6I02_RS03115	COG0577	efflux transmembrane transporter activity
I6I02_RS03135	COG1131	(ABC) transporter
I6I02_RS03150	COG0385	Bile acid
I6I02_RS03165	COG1131	(ABC) transporter
I6I02_RS03175	COG4585	Histidine kinase
I6I02_RS03180	COG2197	response regulator
I6I02_RS03210	COG4555	ABC transporter
I6I02_RS03260	COG0697	spore germination
I6I02_RS03265	COG1621	beta-fructofuranosidase activity
I6I02_RS03265	COG3583	domain protein
I6I02_RS03265	COG5492	domain, Protein
I6I02_RS03270	COG1760	l-serine dehydratase
I6I02_RS03275	COG1760	l-serine dehydratase
I6I02_RS03280	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
I6I02_RS03290	COG2986	histidine ammonia-lyase
I6I02_RS03305	COG1125	glycine betaine transport
I6I02_RS03305	COG0517	IMP dehydrogenase activity
I6I02_RS03315	COG1268	BioY protein
I6I02_RS03320	COG1011	Hydrolase
I6I02_RS03330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I02_RS03335	COG1247	-acetyltransferase
I6I02_RS03340	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
I6I02_RS03350	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
I6I02_RS03365	COG1196	nuclear chromosome segregation
I6I02_RS03400	COG1328	CTP reductase activity
I6I02_RS03400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
I6I02_RS03405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
I6I02_RS03420	COG2801	Transposase and inactivated derivatives
I6I02_RS03440	COG0488	(ABC) transporter
I6I02_RS03460	COG3764	Sortase (surface protein transpeptidase)
I6I02_RS03465	COG0346	lactoylglutathione lyase activity
I6I02_RS03490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
I6I02_RS03495	COG0625	glutathione transferase activity
I6I02_RS03500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
I6I02_RS03505	COG1435	thymidine kinase activity
I6I02_RS03515	COG2890	protein-(glutamine-N5) methyltransferase activity
I6I02_RS03520	COG0009	L-threonylcarbamoyladenylate synthase
I6I02_RS03545	COG1132	(ABC) transporter
I6I02_RS03560	COG1696	Membrane protein involved in D-alanine export
I6I02_RS03570	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
I6I02_RS03575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I6I02_RS03580	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
I6I02_RS03600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
I6I02_RS03605	COG4684	Psort location CytoplasmicMembrane, score
I6I02_RS03610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
I6I02_RS03625	COG0745	RESPONSE REGULATOR receiver
I6I02_RS03630	COG5002	protein histidine kinase activity
I6I02_RS03645	COG2813	Specifically methylates the guanine in position
I6I02_RS03650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
I6I02_RS03655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
I6I02_RS03660	COG0295	cytidine deaminase activity
I6I02_RS03665	COG1744	ABC transporter substrate-binding protein PnrA-like
I6I02_RS03670	COG3845	ABC transporter
I6I02_RS03675	COG4603	Belongs to the binding-protein-dependent transport system permease family
I6I02_RS03680	COG1079	Belongs to the binding-protein-dependent transport system permease family
I6I02_RS03690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
I6I02_RS03690	COG1199	ATP-dependent helicase activity
I6I02_RS03700	COG0436	Aminotransferase
I6I02_RS03705	COG0017	Asparaginyl-tRNA synthetase
I6I02_RS03720	COG0251	oxidation-reduction process
I6I02_RS03730	COG0720	synthase
I6I02_RS03780	COG3443	Belongs to the bacterial solute-binding protein 9 family
I6I02_RS03780	COG0803	Belongs to the bacterial solute-binding protein 9 family
I6I02_RS03800	COG1705	Flagellar rod assembly protein muramidase FlgJ
I6I02_RS03800	COG1388	LysM domain
I6I02_RS03805	COG0583	DNA-binding transcription factor activity
I6I02_RS03810	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
I6I02_RS03820	COG2824	Alkylphosphonate utilization operon protein PhnA
I6I02_RS03825	COG0765	amino acid transport
I6I02_RS03830	COG1126	abc transporter atp-binding protein
I6I02_RS03835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS03840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I6I02_RS03855	COG1064	alcohol dehydrogenase
I6I02_RS03865	COG0518	GMP synthase (glutamine-hydrolyzing) activity
I6I02_RS03865	COG0519	Catalyzes the synthesis of GMP from XMP
I6I02_RS03870	COG2188	Transcriptional regulator
I6I02_RS03880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I6I02_RS03890	COG1827	regulation of RNA biosynthetic process
I6I02_RS03900	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
I6I02_RS03915	COG0758	DNA mediated transformation
I6I02_RS03920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
I6I02_RS03990	COG0028	Belongs to the TPP enzyme family
I6I02_RS03995	COG3527	Alpha-acetolactate decarboxylase
I6I02_RS04000	COG1846	Transcriptional regulator
I6I02_RS04015	COG0517	IMP dehydrogenase activity
I6I02_RS04015	COG1125	glycine betaine transport
I6I02_RS04020	COG1174	glycine betaine transport
I6I02_RS04035	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I6I02_RS04045	COG1122	ATPase activity
I6I02_RS04060	COG1028	Short-chain dehydrogenase reductase Sdr
I6I02_RS04060	COG0604	alcohol dehydrogenase
I6I02_RS04060	COG3321	synthase
I6I02_RS04065	COG0596	Alpha beta hydrolase
I6I02_RS04090	COG1230	cation diffusion facilitator family transporter
I6I02_RS04130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I02_RS04145	COG4607	ABC-type enterochelin transport system periplasmic component
I6I02_RS04150	COG0534	Mate efflux family protein
I6I02_RS04190	COG1293	RNA-binding protein homologous to eukaryotic snRNP
I6I02_RS04210	COG0167	dihydroorotate dehydrogenase activity
I6I02_RS04220	COG0284	orotidine-5'-phosphate decarboxylase activity
I6I02_RS04235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS04240	COG0765	amino acid transport
I6I02_RS04245	COG0737	Belongs to the 5'-nucleotidase family
I6I02_RS04250	COG2207	Transcriptional regulator
I6I02_RS04250	COG1917	Cupin 2, conserved barrel domain protein
I6I02_RS04260	COG1115	amino acid carrier protein
I6I02_RS04265	COG0210	DNA helicase
I6I02_RS04270	COG2873	o-acetylhomoserine
I6I02_RS04300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
I6I02_RS04305	COG0196	riboflavin kinase activity
I6I02_RS04310	COG1393	Belongs to the ArsC family
I6I02_RS04320	COG0483	inositol monophosphate 1-phosphatase activity
I6I02_RS04325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
I6I02_RS04325	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
I6I02_RS04335	COG0573	inorganic phosphate transmembrane transporter activity
I6I02_RS04340	COG0581	inorganic phosphate transmembrane transporter activity
I6I02_RS04355	COG0704	Plays a role in the regulation of phosphate uptake
I6I02_RS04370	COG0095	Lipoate-protein ligase
I6I02_RS04385	COG0058	SHG alpha-glucan phosphorylase activity
I6I02_RS04390	COG1640	4-alpha-glucanotransferase
I6I02_RS04395	COG1609	Transcriptional regulator
I6I02_RS04405	COG1175	transmembrane transport
I6I02_RS04410	COG3833	ABC-type maltose transport systems, permease component
I6I02_RS04415	COG3842	ATPase activity
I6I02_RS04425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
I6I02_RS04430	COG0805	protein transport
I6I02_RS04435	COG0672	)-iron permease
I6I02_RS04440	COG2837	iron assimilation
I6I02_RS04450	COG1523	belongs to the glycosyl hydrolase 13 family
I6I02_RS04455	COG0860	N-Acetylmuramoyl-L-alanine amidase
I6I02_RS04465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I02_RS04470	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I02_RS04475	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I02_RS04475	COG0022	dehydrogenase e1 component
I6I02_RS04480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I6I02_RS04510	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
I6I02_RS04525	COG4667	esterase of the alpha-beta hydrolase superfamily
I6I02_RS04550	COG0628	permease
I6I02_RS04555	COG0406	alpha-ribazole phosphatase activity
I6I02_RS04580	COG0438	transferase activity, transferring glycosyl groups
I6I02_RS04590	COG0562	UDP-galactopyranose mutase
I6I02_RS04595	COG3274	enterobacterial common antigen metabolic process
I6I02_RS04610	COG1216	Glycosyl transferase, family 2
I6I02_RS04615	COG1216	Glycosyl transferase, family 2
I6I02_RS04615	COG1442	glycosyl transferase family 8
I6I02_RS04625	COG0297	glycogen (starch) synthase activity
I6I02_RS04655	COG1316	TRANSCRIPTIONal
I6I02_RS04680	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
I6I02_RS04690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
I6I02_RS04710	COG1573	uracil-dna glycosylase
I6I02_RS04740	COG0291	Belongs to the bacterial ribosomal protein bL35 family
I6I02_RS04745	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
I6I02_RS04775	COG1705	Flagellar rod assembly protein muramidase FlgJ
I6I02_RS04790	COG0628	permease
I6I02_RS04795	COG1051	belongs to the nudix hydrolase family
I6I02_RS04800	COG2177	Part of the ABC transporter FtsEX involved in
I6I02_RS04805	COG2884	Cell division ATP-binding protein ftsE
I6I02_RS04815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
I6I02_RS04825	COG0778	Nitroreductase
I6I02_RS04850	COG2348	transferase activity, transferring amino-acyl groups
I6I02_RS04855	COG2832	Protein of unknown function (DUF454)
I6I02_RS04860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
I6I02_RS04865	COG5002	protein histidine kinase activity
I6I02_RS04870	COG0745	RESPONSE REGULATOR receiver
I6I02_RS04875	COG1126	abc transporter atp-binding protein
I6I02_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS04885	COG0765	amino acid transport
I6I02_RS04890	COG0765	amino acid transport
I6I02_RS04895	COG1126	abc transporter atp-binding protein
I6I02_RS04900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS04905	COG0765	amino acid transport
I6I02_RS04910	COG0765	amino acid transport
I6I02_RS04935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
I6I02_RS04985	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
I6I02_RS04990	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
I6I02_RS04990	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
I6I02_RS05000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
I6I02_RS05005	COG1956	GAF domain-containing protein
I6I02_RS05010	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
I6I02_RS05030	COG0335	large ribosomal subunit rRNA binding
I6I02_RS05035	COG0038	chloride channel
I6I02_RS05050	COG0716	FMN binding
I6I02_RS05075	COG3842	ATPase activity
I6I02_RS05105	COG0469	pyruvate kinase activity
I6I02_RS05120	COG0066	3-isopropylmalate dehydratase activity
I6I02_RS05125	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
I6I02_RS05155	COG1733	regulation of RNA biosynthetic process
I6I02_RS05160	COG0588	phosphoglycerate mutase activity
I6I02_RS05165	COG0167	dihydroorotate dehydrogenase activity
I6I02_RS05175	COG0776	regulation of translation
I6I02_RS05185	COG2755	lipolytic protein G-D-S-L family
I6I02_RS05195	COG0497	DNA recombination
I6I02_RS05200	COG1438	arginine binding
I6I02_RS05205	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
I6I02_RS05230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
I6I02_RS05250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
I6I02_RS05250	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
I6I02_RS05265	COG0300	oxidoreductase activity
I6I02_RS05280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
I6I02_RS05290	COG0772	Belongs to the SEDS family
I6I02_RS05295	COG0366	Alpha amylase catalytic
I6I02_RS05295	COG5263	repeat protein
I6I02_RS05300	COG0366	Alpha amylase catalytic
I6I02_RS05300	COG5263	repeat protein
I6I02_RS05305	COG0366	Alpha amylase catalytic
I6I02_RS05305	COG5263	repeat protein
I6I02_RS05345	COG0107	imidazoleglycerol-phosphate synthase activity
I6I02_RS05355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
I6I02_RS05365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
I6I02_RS05405	COG0647	UMP catabolic process
I6I02_RS05415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
I6I02_RS05430	COG1088	dTDP-glucose 4,6-dehydratase activity
I6I02_RS05440	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
I6I02_RS05450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
I6I02_RS05465	COG2384	SAM-dependent methyltransferase
I6I02_RS05490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
I6I02_RS05495	COG3442	glutamine amidotransferase
I6I02_RS05500	COG0392	lysyltransferase activity
I6I02_RS05500	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
I6I02_RS05520	COG0488	(ABC) transporter
I6I02_RS05530	COG0513	Belongs to the DEAD box helicase family
I6I02_RS05570	COG0372	Belongs to the citrate synthase family
I6I02_RS05575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
I6I02_RS05580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
I6I02_RS05585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6I02_RS05590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
I6I02_RS05600	COG3599	regulation of cell shape
I6I02_RS05610	COG0762	integral membrane protein
I6I02_RS05620	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
I6I02_RS05630	COG0849	cell division
I6I02_RS05655	COG1217	gtp-binding protein TYPA
I6I02_RS05660	COG1940	carbohydrate kinase activity
I6I02_RS05665	COG4483	Protein conserved in bacteria
I6I02_RS05670	COG0735	belongs to the Fur family
I6I02_RS05675	COG0783	Belongs to the Dps family
I6I02_RS05680	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
I6I02_RS05690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
I6I02_RS05700	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
I6I02_RS05735	COG0501	Belongs to the peptidase M48B family
I6I02_RS05740	COG1704	LemA family
I6I02_RS05770	COG4221	oxidoreductase activity
I6I02_RS05785	COG0561	phosphatase activity
I6I02_RS05800	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
I6I02_RS05805	COG0406	alpha-ribazole phosphatase activity
I6I02_RS05825	COG1705	Flagellar rod assembly protein muramidase FlgJ
I6I02_RS05825	COG1388	LysM domain
I6I02_RS05845	COG1914	H( )-stimulated, divalent metal cation uptake system
I6I02_RS05850	COG4443	Transcriptional Coactivator p15 (PC4)
I6I02_RS05860	COG1268	BioY protein
I6I02_RS05870	COG0826	peptidase U32
I6I02_RS05895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
I6I02_RS05910	COG2801	Transposase and inactivated derivatives
I6I02_RS05930	COG2183	response to ionizing radiation
I6I02_RS05935	COG0701	Predicted permease
I6I02_RS05940	COG3689	TIGRFAM TIGR03943 family protein
I6I02_RS05945	COG0659	secondary active sulfate transmembrane transporter activity
I6I02_RS06010	COG2226	methyltransferase
I6I02_RS06015	COG0508	dehydrogenase complex catalyzes the overall conversion of
I6I02_RS06020	COG0022	dehydrogenase e1 component
I6I02_RS06025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
I6I02_RS06030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I02_RS06035	COG3237	CsbD-like
I6I02_RS06040	COG3237	CsbD-like
I6I02_RS06060	COG2261	transglycosylase associated protein
I6I02_RS06075	COG1597	lipid kinase activity
I6I02_RS06090	COG1120	ATPase activity
I6I02_RS06115	COG0477	Major facilitator Superfamily
I6I02_RS06140	COG1418	mRNA catabolic process
I6I02_RS06150	COG1307	EDD domain protein, DegV family
I6I02_RS06155	COG2807	transmembrane transport
I6I02_RS06175	COG0561	phosphatase activity
I6I02_RS06205	COG0454	-acetyltransferase
I6I02_RS06255	COG0077	Prephenate dehydratase
I6I02_RS06265	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
I6I02_RS06280	COG0287	Prephenate dehydrogenase
I6I02_RS06305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
I6I02_RS06340	COG1609	Transcriptional regulator
I6I02_RS06345	COG0006	proline dipeptidase activity
I6I02_RS06350	COG1185	polyribonucleotide nucleotidyltransferase activity
I6I02_RS06365	COG0557	exoribonuclease II activity
I6I02_RS06380	COG2814	Major facilitator Superfamily
I6I02_RS06385	COG0237	dephospho-CoA kinase activity
I6I02_RS06390	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
I6I02_RS06395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
I6I02_RS06400	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
I6I02_RS06410	COG3711	transcriptional antiterminator
I6I02_RS06415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
I6I02_RS06420	COG0768	penicillin binding
I6I02_RS06425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
I6I02_RS06455	COG1126	abc transporter atp-binding protein
I6I02_RS06460	COG0765	amino acid transport
I6I02_RS06465	COG4703	Protein of unknown function (DUF1797)
I6I02_RS06470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
I6I02_RS06475	COG0542	response to heat
I6I02_RS06480	COG0494	nUDIX hydrolase
I6I02_RS06520	COG0539	negative regulation of cytoplasmic translation
I6I02_RS06540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
I6I02_RS06555	COG0187	DNA topoisomerase II activity
I6I02_RS06575	COG2040	homocysteine
I6I02_RS06580	COG0833	amino acid
I6I02_RS06600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
I6I02_RS06610	COG3425	synthase
I6I02_RS06625	COG1272	protein, Hemolysin III
I6I02_RS06650	COG0596	Alpha beta hydrolase
I6I02_RS06665	COG0438	transferase activity, transferring glycosyl groups
I6I02_RS06690	COG0494	nUDIX hydrolase
I6I02_RS06700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I6I02_RS06725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I02_RS06730	COG3850	Histidine kinase
I6I02_RS06730	COG5002	protein histidine kinase activity
I6I02_RS06745	COG2267	carboxylic ester hydrolase activity
I6I02_RS06755	COG0686	Belongs to the AlaDH PNT family
I6I02_RS06760	COG1473	amidohydrolase
I6I02_RS06765	COG1187	pseudouridine synthase activity
I6I02_RS06810	COG1132	(ABC) transporter
I6I02_RS06820	COG0583	DNA-binding transcription factor activity
I6I02_RS06825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
I6I02_RS06910	COG0542	response to heat
I6I02_RS06915	COG1396	sequence-specific DNA binding
I6I02_RS06975	COG0577	efflux transmembrane transporter activity
I6I02_RS06980	COG1136	(ABC) transporter
I6I02_RS06985	COG2274	protein secretion by the type I secretion system
I6I02_RS07000	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I6I02_RS07060	COG4974	Belongs to the 'phage' integrase family
I6I02_RS07160	COG2801	Transposase and inactivated derivatives
I6I02_RS07285	COG2205	protein histidine kinase activity
I6I02_RS07290	COG0745	RESPONSE REGULATOR receiver
I6I02_RS07390	COG0542	response to heat
I6I02_RS07435	COG1131	(ABC) transporter
I6I02_RS07520	COG1725	Transcriptional regulator
I6I02_RS07525	COG0494	nUDIX hydrolase
I6I02_RS07545	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
I6I02_RS07555	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
I6I02_RS07600	COG4555	ABC transporter
I6I02_RS07680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
I6I02_RS07705	COG4974	Belongs to the 'phage' integrase family
I6I02_RS07740	COG3290	protein histidine kinase activity
I6I02_RS07760	COG2801	Transposase and inactivated derivatives
I6I02_RS07805	COG0577	efflux transmembrane transporter activity
I6I02_RS07810	COG1136	(ABC) transporter
I6I02_RS07830	COG0505	Belongs to the CarA family
I6I02_RS07850	COG0564	pseudouridine synthase activity
I6I02_RS07895	COG1263	PTS System
I6I02_RS07895	COG2190	(PTS) system
I6I02_RS07895	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I02_RS07905	COG1113	amino acid transport
I6I02_RS07935	COG1283	sodium-dependent phosphate transmembrane transporter activity
I6I02_RS07955	COG1388	LysM domain
I6I02_RS07955	COG1705	Flagellar rod assembly protein muramidase FlgJ
I6I02_RS07970	COG4467	Involved in initiation control of chromosome replication
I6I02_RS07975	COG1774	PSP1 C-terminal conserved region
I6I02_RS07980	COG0470	DNA polymerase III
I6I02_RS08000	COG0149	triose-phosphate isomerase activity
I6I02_RS08010	COG0772	Belongs to the SEDS family
I6I02_RS08045	COG0356	it plays a direct role in the translocation of protons across the membrane
I6I02_RS08065	COG0519	Catalyzes the synthesis of GMP from XMP
I6I02_RS08085	COG2962	Rard protein
I6I02_RS08100	COG0726	polysaccharide deacetylase
I6I02_RS08105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
I6I02_RS08110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
I6I02_RS08125	COG0436	Aminotransferase
I6I02_RS08130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
I6I02_RS08165	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
I6I02_RS08170	COG4122	O-methyltransferase activity
I6I02_RS08175	COG2223	nitrite transmembrane transporter activity
I6I02_RS08200	COG0583	DNA-binding transcription factor activity
I6I02_RS08205	COG0656	L-ascorbic acid biosynthetic process
I6I02_RS08210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I6I02_RS08210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
I6I02_RS08230	COG1702	phosphate starvation-inducible protein PhoH
I6I02_RS08265	COG0745	RESPONSE REGULATOR receiver
I6I02_RS08270	COG2357	RelA SpoT domain protein
I6I02_RS08295	COG0242	peptide deformylase activity
I6I02_RS08305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
I6I02_RS08325	COG0488	(ABC) transporter
I6I02_RS08380	COG0301	tRNA thio-modification
I6I02_RS08385	COG1104	cysteine desulfurase activity
I6I02_RS08395	COG0285	dihydrofolate synthase activity
I6I02_RS08400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
I6I02_RS08410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I02_RS08410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
I6I02_RS08410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
I6I02_RS08415	COG1105	Belongs to the carbohydrate kinase PfkB family
I6I02_RS08420	COG1349	DNA-binding transcription factor activity
I6I02_RS08445	COG0439	Biotin carboxylase
I6I02_RS08460	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
I6I02_RS08465	COG1028	Short-chain dehydrogenase reductase Sdr
I6I02_RS08470	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
I6I02_RS08490	COG1846	Transcriptional regulator
I6I02_RS08495	COG1024	Enoyl-CoA hydratase
I6I02_RS08500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
I6I02_RS08505	COG0527	aspartate kinase activity
I6I02_RS08600	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
I6I02_RS08605	COG1739	Uncharacterized protein family UPF0029
I6I02_RS08615	COG0517	IMP dehydrogenase activity
I6I02_RS08645	COG4471	UPF0298 protein
I6I02_RS08650	COG3679	Belongs to the UPF0342 family
I6I02_RS08675	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
I6I02_RS08680	COG0626	cystathionine gamma-synthase activity
I6I02_RS08685	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
I6I02_RS08690	COG2244	polysaccharide biosynthetic process
I6I02_RS08725	COG2740	Nucleic-acid-binding protein implicated in transcription termination
I6I02_RS08730	COG0195	Participates in both transcription termination and antitermination
I6I02_RS08740	COG1316	TRANSCRIPTIONal
I6I02_RS08745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
I6I02_RS08750	COG0802	atpase or kinase
I6I02_RS08755	COG2252	PERMEase
I6I02_RS08760	COG0561	phosphatase activity
I6I02_RS08765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
I6I02_RS08775	COG3715	PTS system
I6I02_RS08780	COG3716	PTS system mannose fructose sorbose family IID component
I6I02_RS08795	COG3715	PTS system
I6I02_RS08800	COG3716	PTS system mannose fructose sorbose family IID component
I6I02_RS08825	COG1484	DNA-dependent DNA replication
I6I02_RS08840	COG5002	protein histidine kinase activity
I6I02_RS08845	COG0745	RESPONSE REGULATOR receiver
I6I02_RS08860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I6I02_RS08875	COG1122	ATPase activity
I6I02_RS08890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
I6I02_RS08900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
I6I02_RS08910	COG1464	Belongs to the NlpA lipoprotein family
I6I02_RS08915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
I6I02_RS08920	COG1122	ATPase activity
I6I02_RS08930	COG0310	cobalt ion transport
I6I02_RS08935	COG0829	nickel cation binding
I6I02_RS08945	COG0830	nickel cation binding
I6I02_RS08955	COG0804	urea catabolic process
I6I02_RS08985	COG2274	protein secretion by the type I secretion system
I6I02_RS08995	COG0671	phosphoesterase, PA-phosphatase related
I6I02_RS09000	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
I6I02_RS09010	COG0569	domain protein
I6I02_RS09015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
I6I02_RS09025	COG1187	pseudouridine synthase activity
I6I02_RS09030	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
I6I02_RS09035	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
I6I02_RS09055	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
I6I02_RS09070	COG1309	transcriptional regulator
I6I02_RS09095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I02_RS09100	COG1254	Belongs to the acylphosphatase family
I6I02_RS09115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
I6I02_RS09135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
I6I02_RS09145	COG0116	Belongs to the methyltransferase superfamily
I6I02_RS09170	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I02_RS09175	COG3579	cysteine-type endopeptidase activity
I6I02_RS09190	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
I6I02_RS09195	COG0577	efflux transmembrane transporter activity
I6I02_RS09205	COG0789	Transcriptional regulator
I6I02_RS09215	COG1349	DNA-binding transcription factor activity
I6I02_RS09220	COG0561	phosphatase activity
I6I02_RS09245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
I6I02_RS09250	COG0564	pseudouridine synthase activity
I6I02_RS09280	COG1116	anion transmembrane transporter activity
I6I02_RS09280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
I6I02_RS09285	COG4120	Belongs to the binding-protein-dependent transport system permease family
I6I02_RS09300	COG4589	Belongs to the CDS family
I6I02_RS09320	COG1132	(ABC) transporter
I6I02_RS09325	COG1396	sequence-specific DNA binding
I6I02_RS09340	COG2190	(PTS) system
I6I02_RS09340	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I02_RS09340	COG1263	PTS System
I6I02_RS09350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
I6I02_RS09355	COG1121	(ABC) transporter
I6I02_RS09365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
I6I02_RS09390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
I6I02_RS09395	COG0719	Fe-S assembly protein
I6I02_RS09405	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
I6I02_RS09425	COG0765	amino acid transport
I6I02_RS09430	COG1126	abc transporter atp-binding protein
I6I02_RS09465	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
I6I02_RS09490	COG0737	Belongs to the 5'-nucleotidase family
I6I02_RS09495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
I6I02_RS09505	COG0494	nUDIX hydrolase
I6I02_RS09530	COG0668	transmembrane transport
I6I02_RS09570	COG4720	Psort location CytoplasmicMembrane, score
I6I02_RS09575	COG0351	phosphomethylpyrimidine kinase
I6I02_RS09605	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
I6I02_RS09620	COG1876	peptidase activity
I6I02_RS09625	COG0588	phosphoglycerate mutase activity
I6I02_RS09635	COG3830	Belongs to the UPF0237 family
I6I02_RS09645	COG4509	Sortase family
I6I02_RS09675	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I6I02_RS09685	COG0492	ferredoxin-NADP+ reductase activity
I6I02_RS09690	COG3118	belongs to the thioredoxin family
I6I02_RS09795	COG2217	Heavy metal translocating P-type atpase
I6I02_RS09810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
I6I02_RS09815	COG1476	TRANSCRIPTIONal
I6I02_RS09830	COG3688	RNA-binding protein containing a PIN domain
I6I02_RS09835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
I6I02_RS09845	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
I6I02_RS09860	COG1045	serine acetyltransferase
I6I02_RS09875	COG1686	Belongs to the peptidase S11 family
I6I02_RS09880	COG1686	Belongs to the peptidase S11 family
I6I02_RS09885	COG0542	response to heat
I6I02_RS09890	COG4463	regulation of RNA biosynthetic process
I6I02_RS09910	COG0450	alkyl hydroperoxide reductase
I6I02_RS09915	COG3634	alkyl hydroperoxide reductase activity
I6I02_RS09940	COG2309	aminopeptidase activity
I6I02_RS09945	COG2176	DNA-directed DNA polymerase activity
I6I02_RS10030	COG1393	Belongs to the ArsC family
I6I02_RS10040	COG1546	Belongs to the CinA family
I6I02_RS10040	COG1058	Belongs to the CinA family
I6I02_RS10045	COG2818	Glycosylase
I6I02_RS10085	COG4550	Control of competence regulator ComK, YlbF/YmcA
I6I02_RS10100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
I6I02_RS10130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
I6I02_RS10135	COG0151	Belongs to the GarS family
I6I02_RS10155	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
I6I02_RS10170	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
I6I02_RS10180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
I6I02_RS10195	COG0436	Aminotransferase
I6I02_RS10220	COG1792	Involved in formation and maintenance of cell shape
I6I02_RS10330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
I6I02_RS10360	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
I6I02_RS10365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
I6I02_RS10375	COG0012	GTP binding
I6I02_RS10385	COG0592	DNA-directed DNA polymerase activity
I6I02_RS10395	COG1475	DNA binding
I6I02_RS10400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
I6I02_RS10435	COG0488	(ABC) transporter
I6I02_RS10440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I6I02_RS10470	COG0612	Peptidase, M16
I6I02_RS10480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
I6I02_RS10495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
I6I02_RS10500	COG1388	LysM domain
I6I02_RS10500	COG3584	3D domain protein
I6I02_RS10505	COG0741	lytic transglycosylase activity
I6I02_RS10520	COG2095	MarC family integral membrane protein
I6I02_RS10540	COG0305	Participates in initiation and elongation during chromosome replication
I6I02_RS10560	COG3759	membrane
I6I02_RS10570	COG1511	domain protein
I6I02_RS10570	COG1511	domain protein
I6I02_RS10585	COG1695	Transcriptional regulator
I6I02_RS10590	COG0494	nUDIX hydrolase
I6I02_RS10610	COG0267	Belongs to the bacterial ribosomal protein bL33 family
I6I02_RS10620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
I6I02_RS10625	COG1263	PTS System
I6I02_RS10625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
I6I02_RS10655	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
I6I02_RS10665	COG0602	queuosine metabolic process
I6I02_RS10700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
I6I02_RS10705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
I6I02_RS10740	COG2855	membrane
I6I02_RS10755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
I6I02_RS10775	COG0051	transcription antitermination factor activity, RNA binding
I6I02_RS10845	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
I6I02_RS10880	COG0201	protein transport
I6I02_RS10885	COG0563	adenylate kinase activity