locus_tag	old_locus_tag	gene	Name	start	end	strand	product	note	type	ID	NCBI
HSISS4_RS00005	HSISS4_00001		HSISS4_RS00005	104	1468	+	chromosomal replication initiation protein DnaA		gene	gene0	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00005
HSISS4_RS00010	HSISS4_00002		HSISS4_RS00010	1623	2759	+	DNA polymerase III subunit beta		gene	gene1	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00010
HSISS4_RS00015	HSISS4_00003		HSISS4_RS00015	2811	3002	+	hypothetical protein		gene	gene2	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00015
HSISS4_RS00020	HSISS4_00004		HSISS4_RS00020	3212	4327	+	GTP-binding protein YchF		gene	gene3	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00020
HSISS4_RS00025	HSISS4_00005		HSISS4_RS00025	4400	4969	+	aminoacyl-tRNA hydrolase		gene	gene4	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00025
HSISS4_RS00030	HSISS4_00006		HSISS4_RS00030	4962	8468	+	transcription-repair coupling factor		gene	gene5	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00030
HSISS4_RS00035	HSISS4_00007		HSISS4_RS00035	8654	8929	+	hypothetical protein		gene	gene6	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00035
HSISS4_RS00040	HSISS4_00008		HSISS4_RS00040	8913	9284	+	septum formation initiation protein		gene	gene7	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00040
HSISS4_RS00045	HSISS4_00009		HSISS4_RS00045	9284	9415	+	hypothetical protein		gene	gene8	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00045
HSISS4_RS00050	HSISS4_00010		HSISS4_RS00050	9412	10704	+	hypothetical protein		gene	gene9	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00050
HSISS4_RS00055	HSISS4_00011		HSISS4_RS00055	10704	11969	+	tRNA(Ile)-lysidine synthetase		gene	gene10	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00055
HSISS4_RS00060	HSISS4_00012		HSISS4_RS00060	12051	12593	+	hypoxanthine phosphoribosyltransferase		gene	gene11	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00060
HSISS4_RS00065	HSISS4_00013		HSISS4_RS00065	12613	14592	+	cell division protein FtsH		gene	gene12	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00065
HSISS4_RS00070	HSISS4_r00001		HSISS4_RS00070	14955	16509	+	16S ribosomal RNA		rRNA	gene13	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00070
HSISS4_RS00075	HSISS4_r00002		HSISS4_RS00075	16556	16628	+	tRNA-Ala		tRNA	gene14	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00075
HSISS4_RS00080	HSISS4_r00003		HSISS4_RS00080	16774	19675	+	23S ribosomal RNA		rRNA	gene15	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00080
HSISS4_RS00085	HSISS4_r00004	rrf	rrf	19758	19873	+	5S ribosomal RNA		rRNA	gene16	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00085
HSISS4_RS00090	HSISS4_r00005		HSISS4_RS00090	19879	19951	+	tRNA-Val		tRNA	gene17	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00090
HSISS4_RS00095	HSISS4_r00006		HSISS4_RS00095	19954	20029	+	tRNA-Asp		tRNA	gene18	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00095
HSISS4_RS00100	HSISS4_r00007		HSISS4_RS00100	20045	20117	+	tRNA-Lys		tRNA	gene19	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00100
HSISS4_RS00105	HSISS4_r00008		HSISS4_RS00105	20123	20204	+	tRNA-Leu		tRNA	gene20	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00105
HSISS4_RS00110	HSISS4_r00009		HSISS4_RS00110	20217	20289	+	tRNA-Thr		tRNA	gene21	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00110
HSISS4_RS00115	HSISS4_r00010		HSISS4_RS00115	20296	20367	+	tRNA-Gly		tRNA	gene22	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00115
HSISS4_RS00120	HSISS4_r00011		HSISS4_RS00120	20374	20459	+	tRNA-Leu		tRNA	gene23	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00120
HSISS4_RS00125	HSISS4_r00012		HSISS4_RS00125	20474	20547	+	tRNA-Arg		tRNA	gene24	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00125
HSISS4_RS00130	HSISS4_r00013		HSISS4_RS00130	20554	20627	+	tRNA-Pro		tRNA	gene25	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00130
HSISS4_RS00135	HSISS4_r00014		HSISS4_RS00135	20633	20706	+	tRNA-Met		tRNA	gene26	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00135
HSISS4_RS00140	HSISS4_r00015		HSISS4_RS00140	20723	20796	+	tRNA-Met		tRNA	gene27	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00140
HSISS4_RS00145	HSISS4_r00016		HSISS4_RS00145	20816	20905	+	tRNA-Ser		tRNA	gene28	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00145
HSISS4_RS00150	HSISS4_r00017		HSISS4_RS00150	20915	20988	+	tRNA-Met		tRNA	gene29	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00150
HSISS4_RS00155	HSISS4_r00018		HSISS4_RS00155	20992	21064	+	tRNA-Phe		tRNA	gene30	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00155
HSISS4_RS00160	HSISS4_r00019		HSISS4_RS00160	21075	21145	+	tRNA-Gly		tRNA	gene31	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00160
HSISS4_RS00165	HSISS4_r00020		HSISS4_RS00165	21177	21250	+	tRNA-Ile		tRNA	gene32	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00165
HSISS4_RS00170	HSISS4_r00021		HSISS4_RS00170	21255	21342	+	tRNA-Ser		tRNA	gene33	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00170
HSISS4_RS00175	HSISS4_00014		HSISS4_RS00175	21401	22231	+	rod shape-determining protein MreC		gene	gene34	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00175
HSISS4_RS00180	HSISS4_00015		HSISS4_RS00180	22233	22757	+	rod shape-determining protein MreD		gene	gene35	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00180
HSISS4_RS00185	HSISS4_00016		HSISS4_RS00185	22842	24341	+	CHAP domain-containing protein		gene	gene36	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00185
HSISS4_RS00190	HSISS4_00017		HSISS4_RS00190	24553	25518	+	ribose-phosphate pyrophosphokinase	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP	gene	gene37	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00190
HSISS4_RS00195	HSISS4_00018		HSISS4_RS00195	25611	26786	+	N-acetyl-L%2CL-diaminopimelate aminotransferase	catalyzes the transamination of the aromatic amino acid forming a ketoacid%3B first step in aromatic amino acid degradation in lactococci	gene	gene38	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00195
HSISS4_RS00200	HSISS4_00019		HSISS4_RS00200	26773	27546	+	DNA repair protein RecO		gene	gene39	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00200
HSISS4_RS00205	HSISS4_00020		HSISS4_RS00205	27758	28762	+	phosphate acyltransferase PlsX		gene	gene40	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00205
HSISS4_RS00210	HSISS4_00021		HSISS4_RS00210	28762	29007	+	acyl carrier protein	carries the fatty acid chain in fatty acid biosynthesis	gene	gene41	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00210
HSISS4_RS00215	HSISS4_00022		HSISS4_RS00215	29266	29973	+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase	gene	gene42	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00215
HSISS4_RS00220	HSISS4_00023		HSISS4_RS00220	30040	33765	+	phosphoribosylformylglycinamidine synthase		gene	gene43	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00220
HSISS4_RS00225	HSISS4_00024		HSISS4_RS00225	33920	35359	+	amidophosphoribosyltransferase	Catalyzes first step of the de novo purine nucleotide biosynthetic pathway	gene	gene44	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00225
HSISS4_RS00230	HSISS4_00025		HSISS4_RS00230	35571	36593	+	phosphoribosylformylglycinamidine cyclo-ligase		gene	gene45	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00230
HSISS4_RS00235	HSISS4_00026		HSISS4_RS00235	36593	37147	+	phosphoribosylglycinamide formyltransferase		gene	gene46	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00235
HSISS4_RS00240	HSISS4_00027		HSISS4_RS00240	37223	38770	+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase		gene	gene47	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00240
HSISS4_RS00245	HSISS4_00028		HSISS4_RS00245	38867	40654	+	hypothetical protein		gene	gene48	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00245
HSISS4_RS00250	HSISS4_00029		HSISS4_RS00250	40816	41655	-	choline-binding protein		gene	gene49	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00250
HSISS4_RS00255	HSISS4_00030		HSISS4_RS00255	41962	43224	+	phosphoribosylamine--glycine ligase	catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis	gene	gene50	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00255
HSISS4_RS00260	HSISS4_00031		HSISS4_RS00260	43438	43926	+	phosphoribosyl carboxyaminoimidazole mutase		gene	gene51	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00260
HSISS4_RS00265	HSISS4_00032		HSISS4_RS00265	43913	45004	+	5-(carboxyamino)imidazole ribonucleotide synthase		gene	gene52	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00265
HSISS4_RS00270	HSISS4_00033		HSISS4_RS00270	45036	45935	+	NYN domain-containing protein		gene	gene53	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00270
HSISS4_RS00275	HSISS4_00034		HSISS4_RS00275	46230	47984	+	hypothetical protein		gene	gene54	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00275
HSISS4_RS00280	HSISS4_00035		HSISS4_RS00280	48018	49316	+	adenylosuccinate lyase	Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide	gene	gene55	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00280
HSISS4_RS00285	HSISS4_00036		HSISS4_RS00285	50194	51885	-	arginine--tRNA ligase	catalyzes a two-step reaction%2C first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class-I aminoacyl-tRNA synthetase	gene	gene56	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00285
HSISS4_RS00290	HSISS4_00037		HSISS4_RS00290	52043	52468	+	arginine repressor ArgR	regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes	gene	gene57	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00290
HSISS4_RS00295	HSISS4_00038		HSISS4_RS00295	52468	52827	+	hypothetical protein		gene	gene58	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00295
HSISS4_RS00300	HSISS4_00039		HSISS4_RS00300	52820	55378	+	DNA mismatch repair protein MutS		gene	gene59	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00300
HSISS4_RS00305	HSISS4_00040		HSISS4_RS00305	55412	55867	-	hypothetical protein		gene	gene60	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00305
HSISS4_RS00310	HSISS4_00041		HSISS4_RS00310	55864	56301	-	histidine kinase		gene	gene61	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00310
HSISS4_RS00315	HSISS4_00042		HSISS4_RS00315	56480	56785	+	hypothetical protein		gene	gene62	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00315
HSISS4_RS00320	HSISS4_00043		HSISS4_RS00320	56837	58774	+	DNA mismatch repair protein MutL		gene	gene63	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00320
HSISS4_RS00325	HSISS4_00044		HSISS4_RS00325	58905	59126	+	hypothetical protein		gene	gene64	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00325
HSISS4_RS00330	HSISS4_00045		HSISS4_RS00330	59284	59874	+	Holliday junction ATP-dependent DNA helicase RuvA		gene	gene65	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00330
HSISS4_RS00335	HSISS4_00046		HSISS4_RS00335	59883	60437	+	3-methyladenine DNA glycosylase	constitutive%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine	gene	gene66	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00335
HSISS4_RS00340	HSISS4_00047		HSISS4_RS00340	60534	61802	+	competence/damage-inducible protein A		gene	gene67	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00340
HSISS4_RS00345	HSISS4_00048		HSISS4_RS00345	61838	62977	+	DNA recombination/repair protein RecA		gene	gene68	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00345
HSISS4_RS00350	HSISS4_00049		HSISS4_RS00350	63144	63542	+	arsenate reductase		gene	gene69	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00350
HSISS4_RS00355	HSISS4_r00022		HSISS4_RS00355	63965	65519	+	16S ribosomal RNA		rRNA	gene70	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00355
HSISS4_RS00360	HSISS4_r00023		HSISS4_RS00360	65566	65638	+	tRNA-Ala		tRNA	gene71	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00360
HSISS4_RS00365	HSISS4_r00024		HSISS4_RS00365	65784	68685	+	23S ribosomal RNA		rRNA	gene72	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00365
HSISS4_RS00370	HSISS4_r00025	rrf	rrf	68768	68883	+	5S ribosomal RNA		rRNA	gene73	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00370
HSISS4_RS00375	HSISS4_r00026		HSISS4_RS00375	68889	68961	+	tRNA-Val		tRNA	gene74	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00375
HSISS4_RS00380	HSISS4_r00027		HSISS4_RS00380	68966	69036	+	tRNA-Gly		tRNA	gene75	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00380
HSISS4_RS00385	HSISS4_r00028		HSISS4_RS00385	69070	69143	+	tRNA-Ile		tRNA	gene76	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00385
HSISS4_RS00390	HSISS4_r00029		HSISS4_RS00390	69150	69221	+	tRNA-Glu		tRNA	gene77	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00390
HSISS4_RS00395	HSISS4_r00030		HSISS4_RS00395	69231	69320	+	tRNA-Ser		tRNA	gene78	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00395
HSISS4_RS00400	HSISS4_r00031		HSISS4_RS00400	69330	69403	+	tRNA-Met		tRNA	gene79	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00400
HSISS4_RS00405	HSISS4_r00032		HSISS4_RS00405	69407	69479	+	tRNA-Phe		tRNA	gene80	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00405
HSISS4_RS00410	HSISS4_r00033		HSISS4_RS00410	69494	69574	+	tRNA-Tyr		tRNA	gene81	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00410
HSISS4_RS00415	HSISS4_r00034		HSISS4_RS00415	69580	69650	+	tRNA-Trp		tRNA	gene82	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00415
HSISS4_RS00420	HSISS4_r00035		HSISS4_RS00420	69662	69734	+	tRNA-His		tRNA	gene83	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00420
HSISS4_RS00425	HSISS4_r00036		HSISS4_RS00425	69743	69814	+	tRNA-Gln		tRNA	gene84	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00425
HSISS4_RS00430	HSISS4_r00037		HSISS4_RS00430	69824	69907	+	tRNA-Leu		tRNA	gene85	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00430
HSISS4_RS00435	HSISS4_00050	polC	polC	69959	74353	+	DNA polymerase III subunit alpha	catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B required for leading strand synthesis%3B PolC exhibits 3' to 5' exonuclease activity	gene	gene86	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00435
HSISS4_RS00440	HSISS4_00051		HSISS4_RS00440	74517	75758	+	aminopeptidase T		gene	gene87	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00440
HSISS4_RS00445	HSISS4_00052		HSISS4_RS00445	75778	76008	+	membrane protein		gene	gene88	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00445
HSISS4_RS00450	HSISS4_00053		HSISS4_RS00450	76141	76569	+	MarR family transcriptional regulator		gene	gene89	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00450
HSISS4_RS00455	HSISS4_00054		HSISS4_RS00455	76657	77202	+	hypothetical protein		gene	gene90	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00455
HSISS4_RS00460	HSISS4_r00038		HSISS4_RS00460	77289	77362	-	tRNA-Cys		tRNA	gene91	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00460
HSISS4_RS00465	HSISS4_00055		HSISS4_RS00465	77538	79070	-	alkyl hydroperoxide reductase subunit F		gene	gene92	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00465
HSISS4_RS00470	HSISS4_00056		HSISS4_RS00470	79087	79647	-	alkyl hydroperoxide reductase subunit C	with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols%3B AhpC reduced the hydroperoxide substrate	gene	gene93	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00470
HSISS4_RS00475	HSISS4_00057		HSISS4_RS00475	79920	80687	+	30S ribosomal protein S2		gene	gene94	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00475
HSISS4_RS00480	HSISS4_00058		HSISS4_RS00480	80798	81838	+	elongation factor Ts		gene	gene95	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00480
HSISS4_RS00485	HSISS4_00059		HSISS4_RS00485	81946	82416	-	multidrug SMR transporter		gene	gene96	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00485
HSISS4_RS00490	HSISS4_00060		HSISS4_RS00490	82734	83189	+	hypothetical protein		gene	gene97	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00490
HSISS4_RS00495	HSISS4_00061		HSISS4_RS00495	83190	85640	+	ATP-dependent Clp protease ATP-binding subunit ClpA		gene	gene98	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00495
HSISS4_RS00500	HSISS4_00062		HSISS4_RS00500	85769	87025	-	peptidase M15		gene	gene99	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00500
HSISS4_RS00505	HSISS4_00063		HSISS4_RS00505	87170	88417	-	peptidase M15		gene	gene100	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00505
HSISS4_RS00510	HSISS4_00064		HSISS4_RS00510	88627	90864	+	polyribonucleotide nucleotidyltransferase		gene	gene101	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00510
HSISS4_RS00515	HSISS4_00065		HSISS4_RS00515	90861	91631	+	hypothetical protein		gene	gene102	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00515
HSISS4_RS00520	HSISS4_00066		HSISS4_RS00520	91716	92336	+	serine acetyltransferase		gene	gene103	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00520
HSISS4_RS00525	HSISS4_00068		HSISS4_RS00525	92713	94056	+	cysteine--tRNA ligase		gene	gene104	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00525
HSISS4_RS00530	HSISS4_00069		HSISS4_RS00530	94049	94450	+	ribonuclease III family protein		gene	gene105	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00530
HSISS4_RS00535	HSISS4_00070		HSISS4_RS00535	94741	96417	+	hypothetical protein		gene	gene106	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00535
HSISS4_RS00540	HSISS4_00071		HSISS4_RS00540	96465	97208	+	rRNA methyltransferase		gene	gene107	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00540
HSISS4_RS00545	HSISS4_00072		HSISS4_RS00545	97211	97726	+	DNA-binding protein		gene	gene108	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00545
HSISS4_RS00550	HSISS4_00073		HSISS4_RS00550	97735	98595	+	fatty acid-binding protein DegV		gene	gene109	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00550
HSISS4_RS00555	HSISS4_00074		HSISS4_RS00555	98748	99218	+	hypothetical protein		gene	gene110	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00555
HSISS4_RS00560	HSISS4_00075		HSISS4_RS00560	99228	99428	+	transcriptional regulator		gene	gene111	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00560
HSISS4_RS00565	HSISS4_00076		HSISS4_RS00565	99679	100125	+	50S ribosomal protein L13		gene	gene112	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00565
HSISS4_RS00570	HSISS4_00077		HSISS4_RS00570	100153	100545	+	30S ribosomal protein S9		gene	gene113	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00570
HSISS4_RS00575	HSISS4_00078		HSISS4_RS00575	100655	100972	-	integrase		gene	gene114	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00575
HSISS4_RS00580	HSISS4_00079		HSISS4_RS00580	101371	102039	+	Rhodanese-related sulfurtransferase		gene	gene115	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00580
HSISS4_RS00585	HSISS4_RS00585		HSISS4_RS00585	102346	102660	+	thiol reductase thioredoxin		gene	gene116	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00585
HSISS4_RS00590	HSISS4_00081		HSISS4_RS00590	102669	103589	+	thioredoxin reductase		gene	gene117	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00590
HSISS4_RS00595	HSISS4_00082		HSISS4_RS00595	103586	103855	+	hypothetical protein		gene	gene118	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00595
HSISS4_RS00600	HSISS4_RS00600	rpsN	rpsN	103856	104035	+	30S ribosomal protein S14	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group appear to contain the zinc-binding motif	gene	gene119	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00600
HSISS4_RS00605	HSISS4_00083		HSISS4_RS00605	104055	104705	+	2-hydroxychromene-2-carboxylate isomerase		gene	gene120	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00605
HSISS4_RS00610	HSISS4_00084		HSISS4_RS00610	104865	105427	+	hypothetical protein	frameshifted	gene	gene121	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00610
HSISS4_RS00615	HSISS4_00085		HSISS4_RS00615	105907	106488	+	hypothetical protein		gene	gene122	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00615
HSISS4_RS00620	HSISS4_00086		HSISS4_RS00620	106492	106701	+	transcriptional regulator		gene	gene123	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00620
HSISS4_RS00625	HSISS4_00087		HSISS4_RS00625	107393	107809	+	hypothetical protein		gene	gene124	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00625
HSISS4_RS00630	HSISS4_00088		HSISS4_RS00630	107897	108733	+	sortase		gene	gene125	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00630
HSISS4_RS00635	HSISS4_00089		HSISS4_RS00635	108899	110116	+	hypothetical protein		gene	gene126	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00635
HSISS4_RS00640	HSISS4_00090		HSISS4_RS00640	110437	110703	+	hypothetical protein		gene	gene127	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00640
HSISS4_RS00645	HSISS4_00091		HSISS4_RS00645	110721	112058	+	hypothetical protein		gene	gene128	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00645
HSISS4_RS00650	HSISS4_00092		HSISS4_RS00650	112174	112878	+	hypothetical protein		gene	gene129	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00650
HSISS4_RS00655	HSISS4_00093		HSISS4_RS00655	112865	113662	+	D-alanyl-D-alanine carboxypeptidase		gene	gene130	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00655
HSISS4_RS00660	HSISS4_00094		HSISS4_RS00660	113659	114240	+	peptidoglycan hydrolase		gene	gene131	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00660
HSISS4_RS00665	HSISS4_00095		HSISS4_RS00665	114433	115467	+	heat-inducible transcriptional repressor HrcA		gene	gene132	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00665
HSISS4_RS00670	HSISS4_00096		HSISS4_RS00670	115506	116030	+	nucleotide exchange factor GrpE	with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor	gene	gene133	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00670
HSISS4_RS00675	HSISS4_00097	dnaK	dnaK	116348	118171	+	molecular chaperone DnaK	heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria	gene	gene134	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00675
HSISS4_RS00680	HSISS4_00098		HSISS4_RS00680	118525	119658	+	molecular chaperone DnaJ	chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion	gene	gene135	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00680
HSISS4_RS00685	HSISS4_00099		HSISS4_RS00685	119764	120510	+	tRNA pseudouridine(38%2C39%2C40) synthase TruA		gene	gene136	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00685
HSISS4_RS00690	HSISS4_00100		HSISS4_RS00690	120503	121264	+	hydroxymethylpyrimidine/phosphomethylpyrimidine kinase	catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine	gene	gene137	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00690
HSISS4_RS00695	HSISS4_00101		HSISS4_RS00695	121254	121727	+	substrate-specific component PdxU2 of pyridoxin-related ECF transporter		gene	gene138	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00695
HSISS4_RS00700	HSISS4_r00039		HSISS4_RS00700	122109	123663	+	16S ribosomal RNA		rRNA	gene139	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00700
HSISS4_RS00705	HSISS4_r00040		HSISS4_RS00705	123710	123782	+	tRNA-Ala		tRNA	gene140	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00705
HSISS4_RS00710	HSISS4_r00041		HSISS4_RS00710	123928	126829	+	23S ribosomal RNA		rRNA	gene141	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00710
HSISS4_RS00715	HSISS4_r00042	rrf	rrf	126912	127027	+	5S ribosomal RNA		rRNA	gene142	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00715
HSISS4_RS00720	HSISS4_r00043		HSISS4_RS00720	127033	127106	+	tRNA-Asn		tRNA	gene143	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00720
HSISS4_RS00725	HSISS4_00102		HSISS4_RS00725	127262	127759	+	hypothetical protein		gene	gene144	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00725
HSISS4_RS00730	HSISS4_00103		HSISS4_RS00730	127867	128709	-	mechanosensitive ion channel protein		gene	gene145	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00730
HSISS4_RS00735	HSISS4_00105	tig	tig	128852	130135	+	trigger factor	Tig%3B RopA%3B peptidyl-prolyl cis/trans isomerase%3B promotes folding of newly synthesized proteins%3B binds ribosomal 50S subunit%3B forms a homodimer	gene	gene146	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00735
HSISS4_RS00740	HSISS4_00106		HSISS4_RS00740	130293	130868	+	DNA-directed RNA polymerase subunit delta	participates in both the initiation and recycling phases of transcription%3B in the presence of the delta subunit%2C RNAP displays an increased specificity of transcription%2C a decreased affinity for nucleic acids%2C and an increased efficiency of RNA synthesis because of enhanced recycling	gene	gene147	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00740
HSISS4_RS00745	HSISS4_00107		HSISS4_RS00745	131121	132725	+	CTP synthetase		gene	gene148	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00745
HSISS4_RS00750	HSISS4_00108		HSISS4_RS00750	132820	133290	+	hypothetical protein		gene	gene149	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00750
HSISS4_RS00755	HSISS4_00109		HSISS4_RS00755	133306	133773	+	DNA mismatch repair protein MutT		gene	gene150	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00755
HSISS4_RS00760	HSISS4_00110		HSISS4_RS00760	133752	134705	+	ribosomal protein L11 methyltransferase		gene	gene151	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00760
HSISS4_RS00765	HSISS4_00111		HSISS4_RS00765	134706	135449	+	16S rRNA (uracil(1498)-N(3))-methyltransferase		gene	gene152	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00765
HSISS4_RS00770	HSISS4_00112	cpdB	cpdB	135615	138155	+	2'%2C3'-cyclic-nucleotide 2'-phosphodiesterase	in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface%3B functions during ribonucleic acid degradation%3B 2'%2C3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate	gene	gene153	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00770
HSISS4_RS00775	HSISS4_00113		HSISS4_RS00775	138196	138654	-	flavoprotein		gene	gene154	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00775
HSISS4_RS00780	HSISS4_00114		HSISS4_RS00780	138822	141041	+	(p)ppGpp synthetase		gene	gene155	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00780
HSISS4_RS00785	HSISS4_00115		HSISS4_RS00785	141054	141497	+	D-tyrosyl-tRNA(Tyr) deacylase		gene	gene156	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00785
HSISS4_RS00790	HSISS4_00116		HSISS4_RS00790	141879	145466	+	dextranase precursor		gene	gene157	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00790
HSISS4_RS00795	HSISS4_00117		HSISS4_RS00795	145577	146827	+	threonine dehydratase	catalyzes the formation of 2-oxobutanoate from L-threonine%3B biosynthetic	gene	gene158	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00795
HSISS4_RS00800	HSISS4_00118		HSISS4_RS00800	146954	147568	-	peptide deformylase		gene	gene159	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00800
HSISS4_RS00805	HSISS4_00119		HSISS4_RS00805	147662	148300	-	Crp/Fnr family transcriptional regulator		gene	gene160	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00805
HSISS4_RS00810	HSISS4_00120		HSISS4_RS00810	148408	149565	+	MFS transporter		gene	gene161	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00810
HSISS4_RS00815	HSISS4_00121		HSISS4_RS00815	149715	149984	+	30S ribosomal protein S15		gene	gene162	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00815
HSISS4_RS00820	HSISS4_00122		HSISS4_RS00820	150201	150791	-	hypothetical protein		gene	gene163	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00820
HSISS4_RS00825	HSISS4_00123		HSISS4_RS00825	151090	153657	+	hypothetical protein		gene	gene164	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00825
HSISS4_RS00830	HSISS4_00124		HSISS4_RS00830	153748	154488	-	peptide ABC transporter ATP-binding protein		gene	gene165	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00830
HSISS4_RS00835	HSISS4_00125		HSISS4_RS00835	154488	156035	-	amino acid ABC transporter glutamine-binding protein/permease		gene	gene166	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00835
HSISS4_RS00840	HSISS4_00126		HSISS4_RS00840	156241	157095	+	undecaprenyl-diphosphatase		gene	gene167	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00840
HSISS4_RS00845	HSISS4_00127		HSISS4_RS00845	157155	157526	-	hypothetical protein		gene	gene168	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00845
HSISS4_RS00850	HSISS4_00128		HSISS4_RS00850	157733	158482	+	adaptor protein MecA		gene	gene169	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00850
HSISS4_RS00855	HSISS4_00129		HSISS4_RS00855	158486	159643	+	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase		gene	gene170	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00855
HSISS4_RS00860	HSISS4_00130		HSISS4_RS00860	159805	160575	+	ABC transporter ATP-binding protein		gene	gene171	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00860
HSISS4_RS00865	HSISS4_00131		HSISS4_RS00865	160612	161874	+	Fe-S cluster assembly protein SufD		gene	gene172	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00865
HSISS4_RS00870	HSISS4_00132		HSISS4_RS00870	161928	163160	+	hypothetical protein		gene	gene173	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00870
HSISS4_RS00875	HSISS4_00133		HSISS4_RS00875	163147	163578	+	iron-sulfur cluster assembly scaffold protein		gene	gene174	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00875
HSISS4_RS00880	HSISS4_00134		HSISS4_RS00880	163655	165073	+	Fe-S cluster assembly protein SufB		gene	gene175	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00880
HSISS4_RS00885	HSISS4_00135		HSISS4_RS00885	165247	165606	+	hypothetical protein		gene	gene176	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00885
HSISS4_RS00890	HSISS4_00136		HSISS4_RS00890	165687	166553	+	molecular chaperone Hsp33		gene	gene177	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00890
HSISS4_RS00895	HSISS4_00137		HSISS4_RS00895	166546	167523	+	tRNA-dihydrouridine synthase		gene	gene178	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00895
HSISS4_RS00900	HSISS4_00138		HSISS4_RS00900	167687	168130	+	transcriptional regulator		gene	gene179	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00900
HSISS4_RS00905	HSISS4_00139		HSISS4_RS00905	168132	168839	+	zinc ABC transporter ATP-binding protein		gene	gene180	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00905
HSISS4_RS00910	HSISS4_00140		HSISS4_RS00910	168832	169644	+	zinc ABC transporter inner membrane permease ZnuB		gene	gene181	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00910
HSISS4_RS00915	HSISS4_00141		HSISS4_RS00915	169808	170746	+	malate permease		gene	gene182	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00915
HSISS4_RS00920	HSISS4_00142		HSISS4_RS00920	170901	173087	+	PTS maltose and glucose IIA%2C IIB%2C and IIC component	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene183	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00920
HSISS4_RS00925	HSISS4_00143		HSISS4_RS00925	173185	174000	+	exodeoxyribonuclease III		gene	gene184	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00925
HSISS4_RS00930	HSISS4_00144	pgi	pgi	174104	175453	+	glucose-6-phosphate isomerase	functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family	gene	gene185	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00930
HSISS4_RS00935	HSISS4_00145		HSISS4_RS00935	175646	176518	+	positive transcriptional regulator MutR family		gene	gene186	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00935
HSISS4_RS00940	HSISS4_00146		HSISS4_RS00940	176672	178249	+	micrococin J25 ABC exporter (McjD) family%2C ATPbinding/membrane-spanning protein		gene	gene187	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00940
HSISS4_RS00945	HSISS4_00147		HSISS4_RS00945	178405	179121	+	hypothetical protein		gene	gene188	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00945
HSISS4_RS00950	HSISS4_00148		HSISS4_RS00950	179247	179585	+	preprotein translocase subunit YajC		gene	gene189	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00950
HSISS4_RS00955	HSISS4_00149		HSISS4_RS00955	179714	180463	+	isoprenyl transferase	catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate	gene	gene190	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00955
HSISS4_RS00960	HSISS4_00150		HSISS4_RS00960	180476	181270	+	phosphatidate cytidylyltransferase		gene	gene191	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00960
HSISS4_RS00965	HSISS4_00151		HSISS4_RS00965	181287	182549	+	zinc metalloprotease		gene	gene192	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00965
HSISS4_RS00970	HSISS4_00152		HSISS4_RS00970	182635	184482	+	proline--tRNA ligase		gene	gene193	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00970
HSISS4_RS00975	HSISS4_00153		HSISS4_RS00975	185089	187029	+	ABC transporter substrate-binding protein		gene	gene194	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00975
HSISS4_RS00980	HSISS4_00154		HSISS4_RS00980	187029	187832	+	ABC transporter ATP-binding protein		gene	gene195	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00980
HSISS4_RS00985	HSISS4_00155		HSISS4_RS00985	187998	188285	+	co-chaperone GroES		gene	gene196	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00985
HSISS4_RS00990	HSISS4_00156	groEL	groEL	188330	189949	+	molecular chaperone GroEL	60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth	gene	gene197	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00990
HSISS4_RS00995	HSISS4_00157		HSISS4_RS00995	190024	190728	-	hypothetical protein		gene	gene198	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS00995
HSISS4_RS01000	HSISS4_00159		HSISS4_RS01000	191135	191467	-	hypothetical protein		gene	gene199	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01000
HSISS4_RS01005	HSISS4_00160		HSISS4_RS01005	191647	192519	-	RNA pseudouridine synthase		gene	gene200	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01005
HSISS4_RS01010	HSISS4_00161		HSISS4_RS01010	192585	194912	+	multimodular transpeptidase-transglycosylase		gene	gene201	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01010
HSISS4_RS01015	HSISS4_00163	secE	secE	195122	195298	+	preprotein translocase subunit SecE	forms a complex with SecY and SecG%3B SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane%2C a process driven by ATP and a proton-motive force	gene	gene202	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01015
HSISS4_RS01020	HSISS4_00164		HSISS4_RS01020	195499	196038	+	transcription termination/antitermination protein NusG		gene	gene203	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01020
HSISS4_RS01025	HSISS4_00165		HSISS4_RS01025	196163	196651	+	phosphoesterase		gene	gene204	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01025
HSISS4_RS01030	HSISS4_00166		HSISS4_RS01030	196783	197592	-	haloacid dehalogenase		gene	gene205	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01030
HSISS4_RS01035	HSISS4_00167		HSISS4_RS01035	197585	198352	-	DeoR family transcriptional regulator		gene	gene206	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01035
HSISS4_RS01040	HSISS4_00168		HSISS4_RS01040	198546	201047	+	leucine--tRNA ligase		gene	gene207	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01040
HSISS4_RS01045	HSISS4_00169		HSISS4_RS01045	201084	202340	-	transposase		gene	gene208	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01045
HSISS4_RS01050	HSISS4_00170		HSISS4_RS01050	202641	203054	+	hypothetical protein		gene	gene209	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01050
HSISS4_RS01055	HSISS4_00171		HSISS4_RS01055	203402	204268	+	multidrug ABC transporter ATPase		gene	gene210	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01055
HSISS4_RS01060	HSISS4_00172		HSISS4_RS01060	204268	205110	+	multidrug ABC transporter permease		gene	gene211	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01060
HSISS4_RS01065	HSISS4_00173		HSISS4_RS01065	205129	205584	+	transcriptional regulator		gene	gene212	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01065
HSISS4_RS01070	HSISS4_00174		HSISS4_RS01070	205594	206025	+	hypothetical protein		gene	gene213	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01070
HSISS4_RS01075	HSISS4_00175		HSISS4_RS01075	206107	206817	+	MerR family transcriptional regulator		gene	gene214	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01075
HSISS4_RS01080	HSISS4_00176		HSISS4_RS01080	207029	207712	+	ABC transporter ATP-binding protein		gene	gene215	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01080
HSISS4_RS01085	HSISS4_00177		HSISS4_RS01085	208020	208982	+	permease		gene	gene216	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01085
HSISS4_RS01090	HSISS4_00178		HSISS4_RS01090	209167	210621	+	nicotinate phosphoribosyltransferase	catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate	gene	gene217	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01090
HSISS4_RS01095	HSISS4_00179		HSISS4_RS01095	210633	211454	+	NAD(+) synthetase		gene	gene218	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01095
HSISS4_RS01100	HSISS4_00180		HSISS4_RS01100	211470	211913	+	hypothetical protein		gene	gene219	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01100
HSISS4_RS01105	HSISS4_00181		HSISS4_RS01105	212015	213352	+	aminopeptidase C		gene	gene220	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01105
HSISS4_RS01110	HSISS4_00182		HSISS4_RS01110	213459	215750	-	penicillin-binding protein 1AB		gene	gene221	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01110
HSISS4_RS01115	HSISS4_00183		HSISS4_RS01115	215750	216346	-	Holliday junction resolvase RecU		gene	gene222	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01115
HSISS4_RS01120	HSISS4_00184		HSISS4_RS01120	216423	216938	+	hypothetical protein		gene	gene223	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01120
HSISS4_RS01125	HSISS4_00185		HSISS4_RS01125	217047	217379	+	hypothetical protein		gene	gene224	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01125
HSISS4_RS01130	HSISS4_RS01130	rnpB	rnpB	217395	217762	+	RNase P RNA component class B		ncRNA	gene225	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01130
HSISS4_RS01135	HSISS4_00186		HSISS4_RS01135	217908	219074	+	N-6 DNA methylase		gene	gene226	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01135
HSISS4_RS01140	HSISS4_00187		HSISS4_RS01140	219077	221077	+	hypothetical protein		gene	gene227	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01140
HSISS4_RS01145	HSISS4_00188		HSISS4_RS01145	221186	224281	+	RNA helicase		gene	gene228	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01145
HSISS4_RS01150	HSISS4_00189		HSISS4_RS01150	224437	225153	+	hypothetical protein		gene	gene229	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01150
HSISS4_RS01155	HSISS4_00190		HSISS4_RS01155	225180	226508	+	UDP-N-acetylmuramate--L-alanine ligase		gene	gene230	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01155
HSISS4_RS01160	HSISS4_00191		HSISS4_RS01160	226568	227062	+	GNAT family acetyltransferase		gene	gene231	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01160
HSISS4_RS01165	HSISS4_00192		HSISS4_RS01165	227159	229135	+	aminodeoxychorismate lyase		gene	gene232	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01165
HSISS4_RS01170	HSISS4_00193		HSISS4_RS01170	229220	229702	+	transcription elongation factor GreA		gene	gene233	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01170
HSISS4_RS01175	HSISS4_00194		HSISS4_RS01175	229870	230787	-	protein translocase component YidC		gene	gene234	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01175
HSISS4_RS01180	HSISS4_00195		HSISS4_RS01180	230874	231152	-	acylphosphatase	catalyzes the hydrolysis of acylphosphate	gene	gene235	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01180
HSISS4_RS01185	HSISS4_00196		HSISS4_RS01185	231255	231992	+	rRNA methylase		gene	gene236	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01185
HSISS4_RS01190	HSISS4_00197		HSISS4_RS01190	232094	232597	+	haloacid dehalogenase		gene	gene237	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01190
HSISS4_RS01195	HSISS4_00198		HSISS4_RS01195	232621	233310	+	membrane protein		gene	gene238	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01195
HSISS4_RS01200	HSISS4_00199		HSISS4_RS01200	233347	234483	-	hypothetical protein		gene	gene239	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01200
HSISS4_RS01205	HSISS4_00200		HSISS4_RS01205	234621	235874	+	diaminopimelate decarboxylase		gene	gene240	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01205
HSISS4_RS01210	HSISS4_00201		HSISS4_RS01210	235907	236449	-	TetR family transcriptional regulator		gene	gene241	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01210
HSISS4_RS01215	HSISS4_00202		HSISS4_RS01215	236695	236946	+	hypothetical protein		gene	gene242	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01215
HSISS4_RS01220	HSISS4_00203		HSISS4_RS01220	237010	237825	+	glutamate racemase		gene	gene243	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01220
HSISS4_RS01225	HSISS4_00204		HSISS4_RS01225	237818	238792	+	non-canonical purine NTP pyrophosphatase	HAM1-like protein%3B Rec-dependent growth%3B RgdB%3B yggV%3B it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine	gene	gene244	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01225
HSISS4_RS01230	HSISS4_00205		HSISS4_RS01230	238774	239295	+	phosphoesterase		gene	gene245	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01230
HSISS4_RS01235	HSISS4_00206		HSISS4_RS01235	239292	239774	+	CBS domain-containing protein		gene	gene246	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01235
HSISS4_RS01240	HSISS4_00207		HSISS4_RS01240	239728	240489	+	Tyrosine recombinase nerD		gene	gene247	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01240
HSISS4_RS01245	HSISS4_00208	scpA	scpA	240489	241202	+	segregation/condensation protein A	functions during chromosome segregation%3B may form a condensin-like structure with SMC and ScpB	gene	gene248	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01245
HSISS4_RS01250	HSISS4_00209	scpB	scpB	241195	241776	+	segregation and condensation protein B	functions during chromosome segregation%3B may form a condensin-like structure with SMC and ScpA%3B forms a homodimer	gene	gene249	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01250
HSISS4_RS01255	HSISS4_00210		HSISS4_RS01255	241868	242593	+	ribosomal large subunit pseudouridine synthase B		gene	gene250	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01255
HSISS4_RS01260	HSISS4_00212		HSISS4_RS01260	242864	244303	-	Potassium uptake protein TrkH		gene	gene251	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01260
HSISS4_RS01265	HSISS4_00213		HSISS4_RS01265	244310	245659	-	trk system potassium uptake protein trkA		gene	gene252	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01265
HSISS4_RS01270	HSISS4_00214		HSISS4_RS01270	245937	246446	+	tRNA (cytosine34-2'-O-)-methyltransferase		gene	gene253	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01270
HSISS4_RS01275	HSISS4_00215		HSISS4_RS01275	246757	247314	+	Substrate-specific component RibU of riboflavin ECF transporter		gene	gene254	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01275
HSISS4_RS01280	HSISS4_00216		HSISS4_RS01280	247317	247967	+	phosphatase		gene	gene255	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01280
HSISS4_RS01285	HSISS4_00217		HSISS4_RS01285	248145	249044	+	transcriptional regulator		gene	gene256	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01285
HSISS4_RS01290	HSISS4_00218		HSISS4_RS01290	249219	251315	+	peptide ABC transporter ATP-binding protein		gene	gene257	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01290
HSISS4_RS01295	HSISS4_00219		HSISS4_RS01295	251426	251758	+	membrane protein		gene	gene258	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01295
HSISS4_RS01300	HSISS4_00220		HSISS4_RS01300	251809	253200	-	hypothetical protein		gene	gene259	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01300
HSISS4_RS01305	HSISS4_00221		HSISS4_RS01305	253608	254123	+	urease accessory protein		gene	gene260	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01305
HSISS4_RS01310	HSISS4_00222		HSISS4_RS01310	254148	254450	+	urease subunit gamma		gene	gene261	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01310
HSISS4_RS01315	HSISS4_00223	ureB	ureB	254462	254773	+	urease subunit beta	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta)%3B in Staphylococcus saprophyticus plays a role in bladder invasiveness and may induce the formation of kidney and bladder stones due to the alkalization of urine	gene	gene262	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01315
HSISS4_RS01320	HSISS4_00224	ureC	ureC	254789	256507	+	urease subunit alpha	ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide%3B in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa%3B the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits	gene	gene263	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01320
HSISS4_RS01325	HSISS4_00225		HSISS4_RS01325	256648	257100	+	urease accessory protein UreE		gene	gene264	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01325
HSISS4_RS01330	HSISS4_00226		HSISS4_RS01330	257090	257803	+	urease accessory protein UreF		gene	gene265	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01330
HSISS4_RS01335	HSISS4_00227		HSISS4_RS01335	257833	258447	+	urease accessory protein UreG		gene	gene266	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01335
HSISS4_RS01340	HSISS4_00228		HSISS4_RS01340	258449	259288	+	Urease accessory protein UreD		gene	gene267	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01340
HSISS4_RS01345	HSISS4_00229		HSISS4_RS01345	259292	260269	+	cobalt transporter CbiM	catalyzes the ATP-dependent transport of cobalt	gene	gene268	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01345
HSISS4_RS01350	HSISS4_00230		HSISS4_RS01350	260266	261045	+	transmembrane component NikQ of energizing module of nickel ECF transporter		gene	gene269	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01350
HSISS4_RS01355	HSISS4_00231		HSISS4_RS01355	261047	261763	+	cobalt ABC transporter ATP-binding protein		gene	gene270	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01355
HSISS4_RS01360	HSISS4_00232		HSISS4_RS01360	261930	262778	+	amino acid ABC transporter substrate-binding protein		gene	gene271	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01360
HSISS4_RS01365	HSISS4_00233		HSISS4_RS01365	262939	263841	+	methionine ABC transporter substrate-binding protein		gene	gene272	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01365
HSISS4_RS01370	HSISS4_00234		HSISS4_RS01370	263902	265275	+	peptidase M20		gene	gene273	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01370
HSISS4_RS01375	HSISS4_00235		HSISS4_RS01375	265268	266335	+	methionine ABC transporter ATP-binding protein		gene	gene274	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01375
HSISS4_RS01380	HSISS4_00236		HSISS4_RS01380	266335	267027	+	methionine ABC transporter permease		gene	gene275	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01380
HSISS4_RS01385	HSISS4_00237		HSISS4_RS01385	267150	268358	+	serine/threonine transporter SstT		gene	gene276	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01385
HSISS4_RS01390	HSISS4_00238		HSISS4_RS01390	268508	269356	+	hypothetical protein		gene	gene277	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01390
HSISS4_RS01395	HSISS4_00239		HSISS4_RS01395	269366	269911	+	membrane protein		gene	gene278	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01395
HSISS4_RS01400	HSISS4_00240		HSISS4_RS01400	269977	271653	+	Duplicated ATPase component MtsB of energizingmodule of methionine-regulated ECF transporter		gene	gene279	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01400
HSISS4_RS01405	HSISS4_00241		HSISS4_RS01405	271646	272476	+	transmembrane component MtsC of energizing module of methionine-regulated ECF transporter		gene	gene280	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01405
HSISS4_RS01410	HSISS4_00242		HSISS4_RS01410	272566	273237	-	Potassium uptake protein%2C integral membrane component%2C KtrA		gene	gene281	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01410
HSISS4_RS01415	HSISS4_00243		HSISS4_RS01415	273277	274662	-	ATPase V		gene	gene282	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01415
HSISS4_RS01420	HSISS4_00244		HSISS4_RS01420	274710	275423	-	16S rRNA methyltransferase G		gene	gene283	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01420
HSISS4_RS01425	HSISS4_00245		HSISS4_RS01425	275722	276258	+	DNA-binding protein		gene	gene284	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01425
HSISS4_RS01430	HSISS4_00246		HSISS4_RS01430	276414	277103	+	DNA-binding response regulator		gene	gene285	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01430
HSISS4_RS01435	HSISS4_00247		HSISS4_RS01435	277100	278629	+	two-component sensor histidine kinase		gene	gene286	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01435
HSISS4_RS01440	HSISS4_00248		HSISS4_RS01440	278751	279230	+	transcriptional regulator NrdR		gene	gene287	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01440
HSISS4_RS01445	HSISS4_00249		HSISS4_RS01445	279227	280402	+	helicase DnaB		gene	gene288	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01445
HSISS4_RS01450	HSISS4_00250		HSISS4_RS01450	280406	281308	+	primosomal protein DnaI	Primosomal protein that may act to load helicase DnaC during DNA replication	gene	gene289	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01450
HSISS4_RS01455	HSISS4_00251	engA	engA	281413	282723	+	ribosome biogenesis GTPase Der	EngA%3B essential Neisserial GTPase%3B synchronizes cellular events by interacting with multiple targets with tandem G-domains%3B overexpression in Escherichia coli suppresses rrmJ mutation%3B structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains	gene	gene290	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01455
HSISS4_RS01460	HSISS4_00252		HSISS4_RS01460	282788	283417	+	transcriptional regulator		gene	gene291	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01460
HSISS4_RS01465	HSISS4_00253		HSISS4_RS01465	283452	284729	-	serine--tRNA ligase	catalyzes a two-step reaction%2C first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA	gene	gene292	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01465
HSISS4_RS01470	HSISS4_00254		HSISS4_RS01470	284939	285313	-	PTS mannose transporter accessory protein ManO		gene	gene293	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01470
HSISS4_RS01475	HSISS4_00255		HSISS4_RS01475	285393	286304	-	PTS mannose transporter subunit IID	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel	gene	gene294	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01475
HSISS4_RS01480	HSISS4_00256		HSISS4_RS01480	286319	287134	-	PTS mannose/fructose/sorbose transporter subunit IIC		gene	gene295	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01480
HSISS4_RS01485	HSISS4_00257		HSISS4_RS01485	287202	288194	-	PTS mannose transporter subunit EIIAB	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene296	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01485
HSISS4_RS01490	HSISS4_00258		HSISS4_RS01490	288460	288846	-	hypothetical protein		gene	gene297	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01490
HSISS4_RS01495	HSISS4_00259		HSISS4_RS01495	288859	289773	-	PTS mannose IID component	hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel	gene	gene298	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01495
HSISS4_RS01500	HSISS4_00260		HSISS4_RS01500	289789	290589	-	PTS mannose/fructose/sorbose transporter subunit IIC		gene	gene299	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01500
HSISS4_RS01505	HSISS4_00261		HSISS4_RS01505	290607	291614	-	PTS mannose transporter subunit EIIAB	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene300	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01505
HSISS4_RS01510	HSISS4_00262		HSISS4_RS01510	291993	292730	+	hypothetical protein		gene	gene301	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01510
HSISS4_RS01515	HSISS4_00263		HSISS4_RS01515	292725	293537	-	haloacid dehalogenase		gene	gene302	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01515
HSISS4_RS01520	HSISS4_00264		HSISS4_RS01520	293746	295167	+	guanine permease		gene	gene303	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01520
HSISS4_RS01525	HSISS4_00265		HSISS4_RS01525	295441	295884	+	tRNA threonylcarbamoyladenosine biosynthesis protein TsaE		gene	gene304	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01525
HSISS4_RS01530	HSISS4_00266		HSISS4_RS01530	295877	296398	+	GNAT family acetyltransferase		gene	gene305	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01530
HSISS4_RS01535	HSISS4_00267		HSISS4_RS01535	296407	297660	+	transporter		gene	gene306	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01535
HSISS4_RS01540	HSISS4_00268		HSISS4_RS01540	297813	298286	+	ribosome maturation factor RimP		gene	gene307	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01540
HSISS4_RS01545	HSISS4_00269		HSISS4_RS01545	298352	299551	+	transcription termination/antitermination protein NusA		gene	gene308	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01545
HSISS4_RS01550	HSISS4_00270		HSISS4_RS01550	299572	299868	+	hypothetical protein		gene	gene309	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01550
HSISS4_RS01555	HSISS4_00271		HSISS4_RS01555	299861	300163	+	hypothetical protein		gene	gene310	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01555
HSISS4_RS01560	HSISS4_00272		HSISS4_RS01560	300182	303016	+	translation initiation factor IF-2		gene	gene311	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01560
HSISS4_RS01565	HSISS4_00273		HSISS4_RS01565	303112	303465	+	ribosome-binding factor A		gene	gene312	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01565
HSISS4_RS01570	HSISS4_00274		HSISS4_RS01570	303530	304093	+	decarboxylase		gene	gene313	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01570
HSISS4_RS01575	HSISS4_00275		HSISS4_RS01575	304387	305619	+	peptidoglycan branched peptide synthesis protein		gene	gene314	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01575
HSISS4_RS01580	HSISS4_00276		HSISS4_RS01580	305682	307127	-	UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase	involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine	gene	gene315	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01580
HSISS4_RS01585	HSISS4_00277		HSISS4_RS01585	307222	308853	+	polysaccharide biosynthesis protein		gene	gene316	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01585
HSISS4_RS01590	HSISS4_00278		HSISS4_RS01590	308970	311750	+	cation-transporting ATPase E1-E2 family		gene	gene317	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01590
HSISS4_RS01595	HSISS4_00279		HSISS4_RS01595	312044	313138	+	cystathionine gamma-synthase	catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine	gene	gene318	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01595
HSISS4_RS01600	HSISS4_00280		HSISS4_RS01600	313149	314312	+	aspartate aminotransferase		gene	gene319	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01600
HSISS4_RS01605	HSISS4_00281		HSISS4_RS01605	314348	316069	-	exo-beta-D-fructosidase		gene	gene320	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01605
HSISS4_RS01610	HSISS4_00282		HSISS4_RS01610	316230	319145	+	Fructosyltransfearse Ftf		gene	gene321	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01610
HSISS4_RS01615	HSISS4_00283		HSISS4_RS01615	319235	319864	+	uracil phosphoribosyltransferase		gene	gene322	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01615
HSISS4_RS01620	HSISS4_00284		HSISS4_RS01620	320038	320628	+	ATP-dependent Clp protease proteolytic subunit	hydrolyzes proteins to small peptides%3B with the ATPase subunits ClpA or ClpX%2C ClpP degrades specific substrates	gene	gene323	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01620
HSISS4_RS01625	HSISS4_00285		HSISS4_RS01625	320714	321163	+	hypothetical protein		gene	gene324	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01625
HSISS4_RS01630	HSISS4_00286		HSISS4_RS01630	321156	321437	+	hypothetical protein		gene	gene325	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01630
HSISS4_RS01635	HSISS4_00287		HSISS4_RS01635	321592	322767	+	branched-chain amino acid ABC transporter substrate-binding protein		gene	gene326	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01635
HSISS4_RS01640	HSISS4_00288		HSISS4_RS01640	322811	323695	+	ABC transporter permease		gene	gene327	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01640
HSISS4_RS01645	HSISS4_00289		HSISS4_RS01645	323699	324649	+	branched-chain amino acid ABC transporter permease		gene	gene328	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01645
HSISS4_RS01650	HSISS4_00290		HSISS4_RS01650	324651	325415	+	ABC transporter ATP-binding protein		gene	gene329	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01650
HSISS4_RS01655	HSISS4_00291		HSISS4_RS01655	325415	326125	+	ABC transporter ATP-binding protein		gene	gene330	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01655
HSISS4_RS01660	HSISS4_00292		HSISS4_RS01660	326260	326919	+	acetoin utilization protein AcuB		gene	gene331	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01660
HSISS4_RS01665	HSISS4_00293		HSISS4_RS01665	327068	327994	-	cysteine synthase		gene	gene332	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01665
HSISS4_RS01670	HSISS4_00294		HSISS4_RS01670	328096	328722	-	protein co-occurring with transport system		gene	gene333	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01670
HSISS4_RS01675	HSISS4_00295		HSISS4_RS01675	328777	330096	+	competence protein ComF		gene	gene334	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01675
HSISS4_RS01680	HSISS4_00296		HSISS4_RS01680	330077	330739	+	competence protein ComF		gene	gene335	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01680
HSISS4_RS01685	HSISS4_00297		HSISS4_RS01685	330818	331366	+	ribosome-associated factor Y		gene	gene336	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01685
HSISS4_RS01690	HSISS4_r00044		HSISS4_RS01690	331782	333336	+	16S ribosomal RNA		rRNA	gene337	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01690
HSISS4_RS01695	HSISS4_r00045		HSISS4_RS01695	333383	333455	+	tRNA-Ala		tRNA	gene338	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01695
HSISS4_RS01700	HSISS4_r00046		HSISS4_RS01700	333601	336502	+	23S ribosomal RNA		rRNA	gene339	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01700
HSISS4_RS01705	HSISS4_r00047	rrf	rrf	336585	336700	+	5S ribosomal RNA		rRNA	gene340	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01705
HSISS4_RS01710	HSISS4_r00048		HSISS4_RS01710	336706	336778	+	tRNA-Val		tRNA	gene341	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01710
HSISS4_RS01715	HSISS4_r00049		HSISS4_RS01715	336781	336856	+	tRNA-Asp		tRNA	gene342	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01715
HSISS4_RS01720	HSISS4_r00050		HSISS4_RS01720	336872	336944	+	tRNA-Lys		tRNA	gene343	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01720
HSISS4_RS01725	HSISS4_r00051		HSISS4_RS01725	336950	337031	+	tRNA-Leu		tRNA	gene344	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01725
HSISS4_RS01730	HSISS4_r00052		HSISS4_RS01730	337044	337116	+	tRNA-Thr		tRNA	gene345	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01730
HSISS4_RS01735	HSISS4_r00053		HSISS4_RS01735	337124	337195	+	tRNA-Glu		tRNA	gene346	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01735
HSISS4_RS01740	HSISS4_00298		HSISS4_RS01740	337285	338217	+	manganese-dependent inorganic pyrophosphatase	catalyzes the hydrolysis of pyrophosphate to phosphate	gene	gene347	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01740
HSISS4_RS01745	HSISS4_00299		HSISS4_RS01745	338272	338931	+	hypothetical protein		gene	gene348	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01745
HSISS4_RS01750	HSISS4_00300		HSISS4_RS01750	338961	339494	-	hypothetical protein		gene	gene349	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01750
HSISS4_RS01755	HSISS4_00301	recX	recX	339565	340341	-	regulatory protein	binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities	gene	gene350	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01755
HSISS4_RS01760	HSISS4_00302		HSISS4_RS01760	340376	341731	+	RNA methyltransferase		gene	gene351	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01760
HSISS4_RS01765	HSISS4_00303		HSISS4_RS01765	341841	342833	+	asparagine synthetase A	catalyzes the formation of asparagine from aspartate and ammonia	gene	gene352	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01765
HSISS4_RS01770	HSISS4_00304		HSISS4_RS01770	342986	344344	-	aspartate kinase	catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP%3B lysine and threonine sensitive	gene	gene353	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01770
HSISS4_RS01775	HSISS4_00305		HSISS4_RS01775	344474	345112	+	haloacid dehalogenase		gene	gene354	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01775
HSISS4_RS01780	HSISS4_00306		HSISS4_RS01780	345324	346115	+	enoyl-CoA hydratase	Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA	gene	gene355	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01780
HSISS4_RS01785	HSISS4_00307		HSISS4_RS01785	346220	346654	+	MarR family transcriptional regulator		gene	gene356	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01785
HSISS4_RS01790	HSISS4_00308		HSISS4_RS01790	346654	347616	+	3-oxoacyl-ACP synthase		gene	gene357	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01790
HSISS4_RS01795	HSISS4_00309		HSISS4_RS01795	347680	347904	+	acyl carrier protein		gene	gene358	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01795
HSISS4_RS01800	HSISS4_00310		HSISS4_RS01800	348010	348975	+	enoyl-[acyl-carrier-protein] reductase (FMN)		gene	gene359	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01800
HSISS4_RS01805	HSISS4_00311		HSISS4_RS01805	348998	349918	+	malonyl CoA-ACP transacylase		gene	gene360	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01805
HSISS4_RS01810	HSISS4_00312		HSISS4_RS01810	349931	350665	+	beta-ketoacyl-ACP reductase	catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis	gene	gene361	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01810
HSISS4_RS01815	HSISS4_00313		HSISS4_RS01815	350727	351959	+	beta-ketoacyl-[acyl-carrier-protein] synthase II		gene	gene362	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01815
HSISS4_RS01820	HSISS4_00314		HSISS4_RS01820	351963	352457	+	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit		gene	gene363	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01820
HSISS4_RS01825	HSISS4_00315		HSISS4_RS01825	352454	352879	+	beta-hydroxyacyl-ACP dehydratase		gene	gene364	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01825
HSISS4_RS01830	HSISS4_00317		HSISS4_RS01830	352998	354368	+	acetyl-CoA carboxylase biotin carboxylase subunit	an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism	gene	gene365	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01830
HSISS4_RS01835	HSISS4_00318		HSISS4_RS01835	354374	355240	+	acetyl-CoA carboxylase subunit beta		gene	gene366	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01835
HSISS4_RS01840	HSISS4_00319		HSISS4_RS01840	355237	356007	+	acetyl-CoA carboxylase carboxyl transferase subunit alpha	catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein%3B these proteins present a shorter N-terminus	gene	gene367	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01840
HSISS4_RS01845	HSISS4_00320		HSISS4_RS01845	356036	356518	-	S-ribosylhomocysteine lyase		gene	gene368	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01845
HSISS4_RS01850	HSISS4_00321		HSISS4_RS01850	356662	358269	+	ribonuclease	protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP	gene	gene369	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01850
HSISS4_RS01855	HSISS4_00322		HSISS4_RS01855	358481	359227	+	DeoR family transcriptional regulator		gene	gene370	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01855
HSISS4_RS01860	HSISS4_00323		HSISS4_RS01860	359224	360135	+	1-phosphofructokinase		gene	gene371	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01860
HSISS4_RS01865	HSISS4_00324		HSISS4_RS01865	360132	362108	+	PTS fructose transporter subunit IIC		gene	gene372	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01865
HSISS4_RS01870	HSISS4_00325		HSISS4_RS01870	362256	363608	+	glutathione-disulfide reductase	catalyzes the reduction of 2 glutathione to glutathione disulfide%3B maintains high levels of reduced glutathione in the cytosol%3B involved in redox regulation and oxidative defense	gene	gene373	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01870
HSISS4_RS01875	HSISS4_00326		HSISS4_RS01875	363821	365077	-	dihydrofolate synthase Folylpolyglutamatesynthase		gene	gene374	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01875
HSISS4_RS01880	HSISS4_00327		HSISS4_RS01880	365122	365583	-	hypothetical protein		gene	gene375	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01880
HSISS4_RS01885	HSISS4_00328		HSISS4_RS01885	365692	366837	+	hypothetical protein		gene	gene376	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01885
HSISS4_RS01890	HSISS4_00329		HSISS4_RS01890	366892	368115	+	tRNA sulfurtransferase ThiI	Required for the synthesis of the thiazole moiety	gene	gene377	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01890
HSISS4_RS01895	HSISS4_00330		HSISS4_RS01895	368221	369732	+	accessory Sec system glycosyltransferase GtfA		gene	gene378	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01895
HSISS4_RS01900	HSISS4_00331		HSISS4_RS01900	369725	371044	+	accessory Sec system glycosylation chaperone GtfB		gene	gene379	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01900
HSISS4_RS01905	HSISS4_00332		HSISS4_RS01905	371049	371585	+	hypothetical protein		gene	gene380	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01905
HSISS4_RS01910	HSISS4_00333		HSISS4_RS01910	371813	372127	+	50S ribosomal protein L21		gene	gene381	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01910
HSISS4_RS01915	HSISS4_00334		HSISS4_RS01915	372163	372453	+	50S ribosomal protein L27		gene	gene382	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01915
HSISS4_RS01920	HSISS4_00335		HSISS4_RS01920	372511	373206	+	GNAT family acetyltransferase		gene	gene383	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01920
HSISS4_RS01925	HSISS4_00336		HSISS4_RS01925	373406	373780	+	transposase		gene	gene384	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01925
HSISS4_RS01930	HSISS4_00337		HSISS4_RS01930	373782	374624	+	fatty acid-binding protein DegV		gene	gene385	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01930
HSISS4_RS01935	HSISS4_00338		HSISS4_RS01935	374685	375452	+	4-hydroxy-tetrahydrodipicolinate reductase		gene	gene386	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01935
HSISS4_RS01940	HSISS4_00339		HSISS4_RS01940	375449	376651	+	CCA tRNA nucleotidyltransferase	catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA%3B these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity	gene	gene387	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01940
HSISS4_RS01945	HSISS4_00340		HSISS4_RS01945	376735	378615	+	ATPase components of ABC transporter		gene	gene388	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01945
HSISS4_RS01950	HSISS4_00341		HSISS4_RS01950	378694	379197	-	hypothetical protein		gene	gene389	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01950
HSISS4_RS01955	HSISS4_00342		HSISS4_RS01955	379266	380027	-	NUDIX hydrolase		gene	gene390	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01955
HSISS4_RS01960	HSISS4_00343		HSISS4_RS01960	380084	381190	-	nicotinamide-nucleotide adenylyltransferase		gene	gene391	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01960
HSISS4_RS01965	HSISS4_00344		HSISS4_RS01965	381549	382901	+	glutamate dehydrogenase		gene	gene392	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01965
HSISS4_RS01970	HSISS4_00345		HSISS4_RS01970	383080	384723	+	membrane protein		gene	gene393	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01970
HSISS4_RS01975	HSISS4_00346		HSISS4_RS01975	384881	385291	+	peptide deformylase	cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins%3B binds iron(2+)	gene	gene394	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01975
HSISS4_RS01980	HSISS4_00347		HSISS4_RS01980	385477	385920	+	MarR family transcriptional regulator		gene	gene395	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01980
HSISS4_RS01985	HSISS4_00348		HSISS4_RS01985	385924	387738	+	Lipid A export ATP-binding/permease MsbA		gene	gene396	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01985
HSISS4_RS01990	HSISS4_00349		HSISS4_RS01990	387728	389506	+	Lipid A export ATP-binding/permease MsbA		gene	gene397	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01990
HSISS4_RS01995	HSISS4_00350		HSISS4_RS01995	389614	390237	+	GNAT family N-acetyltransferase		gene	gene398	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS01995
HSISS4_RS02000	HSISS4_00351		HSISS4_RS02000	390385	391008	+	GTP pyrophosphokinase		gene	gene399	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02000
HSISS4_RS02005	HSISS4_00352		HSISS4_RS02005	391010	391687	+	transcriptional regulator		gene	gene400	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02005
HSISS4_RS02010	HSISS4_00353		HSISS4_RS02010	391701	392924	+	histidine kinase		gene	gene401	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02010
HSISS4_RS02015	HSISS4_00354	pyrH	pyrH	393162	393899	+	UMP kinase	Catalyzes the phosphorylation of UMP to UDP	gene	gene402	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02015
HSISS4_RS02020	HSISS4_00355		HSISS4_RS02020	393914	394471	+	ribosome recycling factor		gene	gene403	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02020
HSISS4_RS02025	HSISS4_00356		HSISS4_RS02025	394561	395418	+	hypothetical protein		gene	gene404	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02025
HSISS4_RS02030	HSISS4_00357		HSISS4_RS02030	395427	395642	+	hypothetical protein		gene	gene405	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02030
HSISS4_RS02035	HSISS4_00358		HSISS4_RS02035	395882	397150	+	Group B surface immunogenic protein		gene	gene406	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02035
HSISS4_RS02040	HSISS4_00359		HSISS4_RS02040	397230	398294	+	phosphate starvation protein PhoH		gene	gene407	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02040
HSISS4_RS02045	HSISS4_00360		HSISS4_RS02045	398420	399118	+	hypothetical protein		gene	gene408	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02045
HSISS4_RS02050	HSISS4_00361		HSISS4_RS02050	399271	400359	+	hypothetical protein		gene	gene409	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02050
HSISS4_RS02055	HSISS4_00362		HSISS4_RS02055	400489	401367	+	hypothetical protein		gene	gene410	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02055
HSISS4_RS02060	HSISS4_00363		HSISS4_RS02060	401477	403480	+	methionine--tRNA ligase	methionine--tRNA ligase%3B MetRS%3B adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate%3B some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not%3B four subfamilies exist based on sequence motifs and zinc content	gene	gene411	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02060
HSISS4_RS02065	HSISS4_00364		HSISS4_RS02065	403685	404530	-	aldo/keto reductase		gene	gene412	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02065
HSISS4_RS02070	HSISS4_00365		HSISS4_RS02070	404541	405437	-	LysR family transcriptional regulator		gene	gene413	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02070
HSISS4_RS02075	HSISS4_00366		HSISS4_RS02075	405672	406412	-	CAAX protease		gene	gene414	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02075
HSISS4_RS02080	HSISS4_00367		HSISS4_RS02080	406823	408760	+	glucan-binding protein		gene	gene415	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02080
HSISS4_RS02085	HSISS4_00368		HSISS4_RS02085	410058	411017	+	hypothetical protein		gene	gene416	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02085
HSISS4_RS02090	HSISS4_00369		HSISS4_RS02090	411028	412833	+	oligopeptidase PepB		gene	gene417	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02090
HSISS4_RS02095	HSISS4_00370		HSISS4_RS02095	413050	414270	+	oxalate:formate antiporter		gene	gene418	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02095
HSISS4_RS02100	HSISS4_00371		HSISS4_RS02100	414342	415049	+	O-methyltransferase		gene	gene419	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02100
HSISS4_RS02105	HSISS4_00372		HSISS4_RS02105	415111	416253	+	foldase		gene	gene420	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02105
HSISS4_RS02110	HSISS4_00373		HSISS4_RS02110	416592	417077	+	UDP-N-acetylenolpyruvoylglucosamine reductase	internal stop	gene	gene421	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02110
HSISS4_RS02115	HSISS4_00374	alaS	alaS	417102	419720	+	alanine--tRNA ligase	Catalyzes a two-step reaction%2C first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA	gene	gene422	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02115
HSISS4_RS02120	HSISS4_00375		HSISS4_RS02120	419896	422451	+	cell wall protein precursor		gene	gene423	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02120
HSISS4_RS02125	HSISS4_00376		HSISS4_RS02125	422562	423527	-	integrase		gene	gene424	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02125
HSISS4_RS02130	HSISS4_00377		HSISS4_RS02130	423524	424201	-	transposase		gene	gene425	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02130
HSISS4_RS02135	HSISS4_00378		HSISS4_RS02135	424458	425192	+	DNA-binding response regulator		gene	gene426	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02135
HSISS4_RS02140	HSISS4_00379		HSISS4_RS02140	425189	426508	+	histidine kinase		gene	gene427	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02140
HSISS4_RS02145	HSISS4_00380		HSISS4_RS02145	426606	427256	+	hypothetical protein		gene	gene428	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02145
HSISS4_RS02150	HSISS4_00381		HSISS4_RS02150	427531	430671	+	hypothetical protein		gene	gene429	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02150
HSISS4_RS02155	HSISS4_00382		HSISS4_RS02155	430804	431586	+	aliphatic amidase amiE		gene	gene430	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02155
HSISS4_RS02160	HSISS4_00383		HSISS4_RS02160	431596	432777	+	glutamine-dependent2-keto-4-methyl-thiobutyrate aminotransferase		gene	gene431	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02160
HSISS4_RS02165	HSISS4_00384		HSISS4_RS02165	432905	433927	+	N-acetyl-gamma-glutamyl-phosphate reductase		gene	gene432	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02165
HSISS4_RS02170	HSISS4_00385		HSISS4_RS02170	433956	435149	+	glutamate N-acetyltransferase		gene	gene433	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02170
HSISS4_RS02175	HSISS4_00386		HSISS4_RS02175	435176	435913	+	acetylglutamate kinase		gene	gene434	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02175
HSISS4_RS02180	HSISS4_00387	argD	argD	435917	437047	+	acetylornithine aminotransferase		gene	gene435	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02180
HSISS4_RS02185	HSISS4_00388		HSISS4_RS02185	437088	437966	-	polysaccharide deacetylase		gene	gene436	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02185
HSISS4_RS02190	HSISS4_00389		HSISS4_RS02190	438141	439427	+	homoserine dehydrogenase		gene	gene437	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02190
HSISS4_RS02195	HSISS4_00390		HSISS4_RS02195	439511	440371	+	homoserine kinase		gene	gene438	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02195
HSISS4_RS02200	HSISS4_00391		HSISS4_RS02200	440364	441248	+	protein RarD		gene	gene439	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02200
HSISS4_RS02205	HSISS4_00392		HSISS4_RS02205	441361	441978	+	hypothetical protein		gene	gene440	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02205
HSISS4_RS02210	HSISS4_00393		HSISS4_RS02210	442112	442315	+	hypothetical protein		gene	gene441	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02210
HSISS4_RS02215	HSISS4_00394		HSISS4_RS02215	442763	443341	+	hypothetical protein		gene	gene442	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02215
HSISS4_RS02220	HSISS4_00395		HSISS4_RS02220	443328	443888	+	acetyltransferase		gene	gene443	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02220
HSISS4_RS02225	HSISS4_00396		HSISS4_RS02225	443888	444466	+	shikimate kinase		gene	gene444	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02225
HSISS4_RS02230	HSISS4_00397	valS	valS	444459	447110	+	valine--tRNA ligase	valine--tRNA ligase%3B ValRS%3B converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val)%3B class-I aminoacyl-tRNA synthetase type 1 subfamily%3B has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain	gene	gene445	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02230
HSISS4_RS02235	HSISS4_00398		HSISS4_RS02235	447182	449593	+	hypothetical protein		gene	gene446	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02235
HSISS4_RS02240	HSISS4_00399		HSISS4_RS02240	450105	450302	+	F0F1 ATP synthase subunit C	produces ATP from ADP in the presence of a proton gradient across the membrane%3B subunit C is part of the membrane proton channel F0	gene	gene447	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02240
HSISS4_RS02245	HSISS4_00400		HSISS4_RS02245	450335	451042	+	F0F1 ATP synthase subunit A		gene	gene448	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02245
HSISS4_RS02250	HSISS4_00401		HSISS4_RS02250	451063	451560	+	F0F1 ATP synthase subunit B		gene	gene449	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02250
HSISS4_RS02255	HSISS4_00402		HSISS4_RS02255	451560	452096	+	ATP synthase delta chain		gene	gene450	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02255
HSISS4_RS02260	HSISS4_00403		HSISS4_RS02260	452112	453617	+	ATP synthase subunit alpha	produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit	gene	gene451	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02260
HSISS4_RS02265	HSISS4_00404		HSISS4_RS02265	453636	454514	+	F0F1 ATP synthase subunit gamma		gene	gene452	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02265
HSISS4_RS02270	HSISS4_00405		HSISS4_RS02270	454592	455998	+	ATP synthase subunit beta		gene	gene453	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02270
HSISS4_RS02275	HSISS4_00406		HSISS4_RS02275	456011	456427	+	F0F1 ATP synthase subunit epsilon		gene	gene454	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02275
HSISS4_RS02280	HSISS4_00407		HSISS4_RS02280	456689	457969	+	cell division protein FtsW		gene	gene455	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02280
HSISS4_RS02285	HSISS4_00408	tuf	tuf	458207	459403	+	elongation factor Tu	EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu	gene	gene456	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02285
HSISS4_RS02290	HSISS4_00409		HSISS4_RS02290	459658	460416	+	triose-phosphate isomerase		gene	gene457	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02290
HSISS4_RS02295	HSISS4_00410		HSISS4_RS02295	460682	462667	+	transketolase		gene	gene458	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02295
HSISS4_RS02300	HSISS4_r00054		HSISS4_RS02300	462761	462833	+	tRNA-Thr		tRNA	gene459	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02300
HSISS4_RS02305	HSISS4_00411		HSISS4_RS02305	462956	463585	+	dTMP kinase		gene	gene460	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02305
HSISS4_RS02310	HSISS4_00412		HSISS4_RS02310	463594	464469	+	DNA polymerase III delta prime subunit	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.	gene	gene461	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02310
HSISS4_RS02315	HSISS4_00413		HSISS4_RS02315	464466	465272	+	Signal peptidase-like protein		gene	gene462	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02315
HSISS4_RS02320	HSISS4_00414		HSISS4_RS02320	465259	465579	+	DNA replication initiation control protein YabA		gene	gene463	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02320
HSISS4_RS02325	HSISS4_00415		HSISS4_RS02325	465582	466448	+	rRNA (cytidine-2'-O-)-methyltransferase		gene	gene464	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02325
HSISS4_RS02330	HSISS4_00416		HSISS4_RS02330	466586	467821	+	Ammonium transporter family		gene	gene465	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02330
HSISS4_RS02335	HSISS4_00417		HSISS4_RS02335	467832	468173	+	nitrogen regulatory protein P-II		gene	gene466	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02335
HSISS4_RS02340	HSISS4_00418		HSISS4_RS02340	468265	468921	+	peptidoglycan hydrolase		gene	gene467	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02340
HSISS4_RS02345	HSISS4_00419		HSISS4_RS02345	468939	469760	+	haloacid dehalogenase		gene	gene468	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02345
HSISS4_RS02350	HSISS4_00420		HSISS4_RS02350	469778	470287	-	membrane protein		gene	gene469	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02350
HSISS4_RS02355	HSISS4_00421		HSISS4_RS02355	470512	471588	+	hypothetical protein		gene	gene470	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02355
HSISS4_RS02360	HSISS4_00422		HSISS4_RS02360	471726	473357	+	sodium-dependent phosphate transporter		gene	gene471	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02360
HSISS4_RS02365	HSISS4_00423		HSISS4_RS02365	473442	474590	+	N-acetylglucosamine-6-phosphate deacetylase		gene	gene472	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02365
HSISS4_RS02370	HSISS4_00424		HSISS4_RS02370	474696	475940	+	hypothetical protein		gene	gene473	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02370
HSISS4_RS02375	HSISS4_00425	glyQ	glyQ	476395	477312	+	glycine--tRNA ligase subunit alpha	glycine--tRNA ligase alpha chain%3B GlyRS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA	gene	gene474	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02375
HSISS4_RS02380	HSISS4_00426		HSISS4_RS02380	477595	479631	+	glycine--tRNA ligase subunit beta		gene	gene475	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02380
HSISS4_RS02385	HSISS4_00427		HSISS4_RS02385	479665	479922	+	hypothetical protein		gene	gene476	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02385
HSISS4_RS02390	HSISS4_00428		HSISS4_RS02390	480091	481482	+	histidine transporter (permease)		gene	gene477	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02390
HSISS4_RS02395	HSISS4_00429		HSISS4_RS02395	481552	482187	-	hypothetical protein		gene	gene478	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02395
HSISS4_RS02400	HSISS4_00430		HSISS4_RS02400	482493	484394	+	PTS beta-glucoside transporter subunit EIIBCA	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene479	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02400
HSISS4_RS02405	HSISS4_00431		HSISS4_RS02405	484431	485189	-	peptidyl-prolyl cis-trans isomerase		gene	gene480	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02405
HSISS4_RS02410	HSISS4_00432		HSISS4_RS02410	485477	486862	+	hypothetical protein		gene	gene481	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02410
HSISS4_RS02415	HSISS4_00433		HSISS4_RS02415	487254	487490	+	hypothetical protein		gene	gene482	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02415
HSISS4_RS02420	HSISS4_00434		HSISS4_RS02420	487512	487979	+	transcriptional regulator		gene	gene483	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02420
HSISS4_RS02425	HSISS4_00435		HSISS4_RS02425	488066	488395	+	hypothetical protein		gene	gene484	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02425
HSISS4_RS02430	HSISS4_00436		HSISS4_RS02430	488611	489849	+	hypothetical protein		gene	gene485	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02430
HSISS4_RS02435	HSISS4_00437		HSISS4_RS02435	489965	490870	+	LysR family transcriptional regulator		gene	gene486	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02435
HSISS4_RS02440	HSISS4_00438		HSISS4_RS02440	490879	491340	+	signal peptidase II	lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis	gene	gene487	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02440
HSISS4_RS02445	HSISS4_00439		HSISS4_RS02445	491324	492214	+	RNA pseudouridine synthase		gene	gene488	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02445
HSISS4_RS02450	HSISS4_00440		HSISS4_RS02450	492435	492956	+	phosphoribosyltransferase		gene	gene489	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02450
HSISS4_RS02455	HSISS4_00441		HSISS4_RS02455	493261	494538	+	uracil permease		gene	gene490	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02455
HSISS4_RS02460	HSISS4_00442		HSISS4_RS02460	494563	495489	+	aspartate carbamoyltransferase		gene	gene491	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02460
HSISS4_RS02465	HSISS4_00443		HSISS4_RS02465	495651	496739	+	carbamoyl phosphate synthase small subunit		gene	gene492	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02465
HSISS4_RS02470	HSISS4_00444		HSISS4_RS02470	496970	500149	+	carbamoyl phosphate synthase large subunit		gene	gene493	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02470
HSISS4_RS02475	HSISS4_00445		HSISS4_RS02475	500515	501270	+	protein-L-isoD(D-D) O-methyltransferase		gene	gene494	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02475
HSISS4_RS02480	HSISS4_00446		HSISS4_RS02480	501333	502586	+	efflux transporter periplasmic adaptor subunit		gene	gene495	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02480
HSISS4_RS02485	HSISS4_00447		HSISS4_RS02485	502579	503283	+	ABC transporter ATP-binding protein		gene	gene496	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02485
HSISS4_RS02490	HSISS4_00448		HSISS4_RS02490	503293	504501	+	ABC transporter permease		gene	gene497	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02490
HSISS4_RS02495	HSISS4_00449		HSISS4_RS02495	504792	505295	+	50S ribosomal protein L10		gene	gene498	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02495
HSISS4_RS02500	HSISS4_00450	rplL	rplL	505371	505739	+	50S ribosomal protein L7/L12	present in two forms%3B L12 is normal%2C while L7 is aminoacylated at the N-terminal serine%3B the only multicopy ribosomal protein%3B 4:1 ratio of L7/L12 per ribosome%3B two L12 dimers bind L10%3B critically important for translation efficiency and fidelity%3B stimulates GTPase activity of translation factors	gene	gene499	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02500
HSISS4_RS02505	HSISS4_00453		HSISS4_RS02505	506215	507192	+	hypothetical protein		gene	gene500	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02505
HSISS4_RS02510	HSISS4_00454		HSISS4_RS02510	507250	507843	+	hypothetical protein		gene	gene501	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02510
HSISS4_RS02515	HSISS4_00455		HSISS4_RS02515	508071	509624	+	choline transporter		gene	gene502	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02515
HSISS4_RS02520	HSISS4_00456		HSISS4_RS02520	509987	511723	+	ABC transporter ATP-binding/permease		gene	gene503	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02520
HSISS4_RS02525	HSISS4_00457		HSISS4_RS02525	511736	513523	+	ABC transporter ATP-binding/permease		gene	gene504	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02525
HSISS4_RS02530	HSISS4_00458		HSISS4_RS02530	513621	514664	-	S-adenosylmethionine:tRNA ribosyltransferase-isomerase		gene	gene505	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02530
HSISS4_RS02535	HSISS4_00459		HSISS4_RS02535	514817	515518	+	glucosamine-6-phosphate deaminase		gene	gene506	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02535
HSISS4_RS02540	HSISS4_00460		HSISS4_RS02540	515527	515874	+	hypothetical protein		gene	gene507	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02540
HSISS4_RS02545	HSISS4_00461		HSISS4_RS02545	516044	517027	+	Rhodanese domain protein UPF0176%2C Firmicutes subgroup		gene	gene508	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02545
HSISS4_RS02550	HSISS4_00462		HSISS4_RS02550	517145	517828	+	membrane protein		gene	gene509	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02550
HSISS4_RS02555	HSISS4_00463		HSISS4_RS02555	517961	518680	+	16S rRNA pseudouridine(516) synthase		gene	gene510	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02555
HSISS4_RS02560	HSISS4_00464		HSISS4_RS02560	518926	520071	+	Aminoacylase/N-acyl-L-aminoacidamidohydrolase/hippurate hydrolase		gene	gene511	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02560
HSISS4_RS02565	HSISS4_00466		HSISS4_RS02565	520520	521632	+	alanine dehydrogenase		gene	gene512	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02565
HSISS4_RS02570	HSISS4_00467		HSISS4_RS02570	521824	522237	+	hypothetical protein		gene	gene513	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02570
HSISS4_RS02575	HSISS4_00468		HSISS4_RS02575	522273	523073	+	hydrolase		gene	gene514	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02575
HSISS4_RS02580	HSISS4_00469		HSISS4_RS02580	523215	524531	+	pyridine nucleotide-disulfide oxidoreductase	Involved in disulfide oxidoreductase activity and electron transport	gene	gene515	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02580
HSISS4_RS02585	HSISS4_00470		HSISS4_RS02585	524774	525652	+	mevalonate kinase		gene	gene516	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02585
HSISS4_RS02590	HSISS4_00471		HSISS4_RS02590	525634	526578	+	diphosphomevalonate decarboxylase		gene	gene517	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02590
HSISS4_RS02595	HSISS4_00472		HSISS4_RS02595	526571	527566	+	phosphomevalonate kinase		gene	gene518	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02595
HSISS4_RS02600	HSISS4_00473		HSISS4_RS02600	527616	528620	+	type 2 isopentenyl-diphosphate Delta-isomerase		gene	gene519	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02600
HSISS4_RS02605	HSISS4_00474		HSISS4_RS02605	528780	529253	+	transposase		gene	gene520	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02605
HSISS4_RS02610	HSISS4_00475		HSISS4_RS02610	529469	530434	-	integrase		gene	gene521	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02610
HSISS4_RS02615	HSISS4_00476		HSISS4_RS02615	530431	531108	-	transposase		gene	gene522	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02615
HSISS4_RS02620	HSISS4_RS02620		HSISS4_RS02620	531313	532152	+	ABC transporter ATP-binding protein	internal stop	gene	gene523	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02620
HSISS4_RS02625	HSISS4_00479		HSISS4_RS02625	532145	532864	+	membrane spanning protein		gene	gene524	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02625
HSISS4_RS02630	HSISS4_00480		HSISS4_RS02630	533417	536077	+	magnesium-translocating P-type ATPase	P-type%3B involved in magnesium transport into the cytoplasm	gene	gene525	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02630
HSISS4_RS02635	HSISS4_00481	glmU	glmU	536363	537745	+	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase	forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis	gene	gene526	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02635
HSISS4_RS02640	HSISS4_00482		HSISS4_RS02640	537825	538373	+	ADP-ribose pyrophosphatase		gene	gene527	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02640
HSISS4_RS02645	HSISS4_00483		HSISS4_RS02645	538377	538637	+	hypothetical protein		gene	gene528	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02645
HSISS4_RS02650	HSISS4_00484		HSISS4_RS02650	538704	539396	+	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine	gene	gene529	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02650
HSISS4_RS02655	HSISS4_00485		HSISS4_RS02655	539789	542815	+	YSIRK signal domain/LPXTG anchor domain surface protein		gene	gene530	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02655
HSISS4_RS02660	HSISS4_00486		HSISS4_RS02660	542946	543944	+	glycosyl transferase LafB		gene	gene531	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02660
HSISS4_RS02665	HSISS4_00487		HSISS4_RS02665	543945	545267	+	glycosyl transferase LafA		gene	gene532	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02665
HSISS4_RS02670	HSISS4_00488		HSISS4_RS02670	545726	546118	+	hypothetical protein		gene	gene533	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02670
HSISS4_RS02675	HSISS4_00489		HSISS4_RS02675	546167	548113	+	threonine--tRNA ligase		gene	gene534	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02675
HSISS4_RS02680	HSISS4_00490		HSISS4_RS02680	548163	549101	+	hypothetical protein		gene	gene535	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02680
HSISS4_RS02685	HSISS4_00491		HSISS4_RS02685	549131	550189	+	hypothetical protein		gene	gene536	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02685
HSISS4_RS02690	HSISS4_00492		HSISS4_RS02690	550263	550454	-	phage shock protein C%2C PspC		gene	gene537	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02690
HSISS4_RS02695	HSISS4_00493		HSISS4_RS02695	550511	551188	-	hemolysin III		gene	gene538	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02695
HSISS4_RS02700	HSISS4_00494		HSISS4_RS02700	551181	551630	-	hypothetical protein		gene	gene539	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02700
HSISS4_RS02705	HSISS4_00495		HSISS4_RS02705	551799	553070	-	hydroxymethylglutaryl-CoA reductase		gene	gene540	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02705
HSISS4_RS02710	HSISS4_00496		HSISS4_RS02710	553072	554238	-	hydroxymethylglutaryl-CoA synthase		gene	gene541	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02710
HSISS4_RS02715	HSISS4_00497		HSISS4_RS02715	554710	555570	+	thymidylate synthase		gene	gene542	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02715
HSISS4_RS02720	HSISS4_00498		HSISS4_RS02720	555678	556181	+	dihydrofolate reductase		gene	gene543	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02720
HSISS4_RS02725	HSISS4_00500		HSISS4_RS02725	556374	557600	+	ATP-dependent Clp protease ATP-binding subunit ClpX		gene	gene544	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02725
HSISS4_RS02730	HSISS4_00501	engB	engB	557610	558209	+	GTP-binding protein	binds guanine nucleotides%3B in Escherichia coli depletion results in defective cell division and filamentation%3B in Bacillus subtilis this gene is essential	gene	gene545	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02730
HSISS4_RS02735	HSISS4_00503		HSISS4_RS02735	558339	559716	+	amino acid permease	frameshifted	gene	gene546	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02735
HSISS4_RS02740	HSISS4_00504	mmuM	mmuM	559728	560678	+	homocysteine S-methyltransferase	converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines	gene	gene547	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02740
HSISS4_RS02745	HSISS4_00505		HSISS4_RS02745	560791	561045	+	hypothetical protein		gene	gene548	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02745
HSISS4_RS02750	HSISS4_00506		HSISS4_RS02750	561120	561497	+	hypothetical protein		gene	gene549	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02750
HSISS4_RS02755	HSISS4_00507		HSISS4_RS02755	561615	562256	-	acyl-phosphate--glycerol-3-phosphate O-acyltransferase		gene	gene550	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02755
HSISS4_RS02760	HSISS4_00508	gyrB	gyrB	562394	564343	+	DNA gyrase subunit B	negatively supercoils closed circular double-stranded DNA	gene	gene551	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02760
HSISS4_RS02765	HSISS4_00509		HSISS4_RS02765	564499	565047	+	membrane protein		gene	gene552	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02765
HSISS4_RS02770	HSISS4_00511		HSISS4_RS02770	565666	568122	+	Topoisomerase IV subunit A		gene	gene553	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02770
HSISS4_RS02775	HSISS4_00512		HSISS4_RS02775	568288	569310	+	branched chain amino acid aminotransferase		gene	gene554	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02775
HSISS4_RS02780	HSISS4_00513		HSISS4_RS02780	569429	569659	+	hypothetical protein		gene	gene555	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02780
HSISS4_RS02785	HSISS4_r00055		HSISS4_RS02785	569720	569800	+	tRNA-Tyr		tRNA	gene556	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02785
HSISS4_RS02790	HSISS4_r00056		HSISS4_RS02790	569869	569940	+	tRNA-Gln		tRNA	gene557	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02790
HSISS4_RS02795	HSISS4_00514	rpsA	rpsA	570061	571263	+	30S ribosomal protein S1	in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins	gene	gene558	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02795
HSISS4_RS02800	HSISS4_r00057		HSISS4_RS02800	571333	571404	+	tRNA-Arg		tRNA	gene559	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02800
HSISS4_RS02805	HSISS4_RS02805	ssrA	ssrA	571656	572005	+	transfer-messenger RNA		tmRNA	gene560	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02805
HSISS4_RS02810	HSISS4_00515		HSISS4_RS02810	572051	572671	+	hypothetical protein		gene	gene561	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02810
HSISS4_RS02815	HSISS4_00516		HSISS4_RS02815	572754	573437	+	hypothetical protein		gene	gene562	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02815
HSISS4_RS02820	HSISS4_00517		HSISS4_RS02820	573415	574650	+	peptidoglycan branched peptide synthesis protein		gene	gene563	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02820
HSISS4_RS02825	HSISS4_00518		HSISS4_RS02825	574748	575710	+	NAD-dependent oxidoreductase		gene	gene564	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02825
HSISS4_RS02830	HSISS4_00519		HSISS4_RS02830	575756	576058	-	hypothetical protein		gene	gene565	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02830
HSISS4_RS02835	HSISS4_00520		HSISS4_RS02835	576068	576526	-	NUDIX hydrolase		gene	gene566	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02835
HSISS4_RS02840	HSISS4_00521		HSISS4_RS02840	576669	578939	-	Clp protease ClpX		gene	gene567	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02840
HSISS4_RS02845	HSISS4_00522		HSISS4_RS02845	579182	580162	+	ornithine carbamoyltransferase		gene	gene568	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02845
HSISS4_RS02850	HSISS4_00523		HSISS4_RS02850	580231	580461	+	hypothetical protein		gene	gene569	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02850
HSISS4_RS02855	HSISS4_00524		HSISS4_RS02855	580775	581455	+	glutamine ABC transporter permease		gene	gene570	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02855
HSISS4_RS02860	HSISS4_00525	glnQ	glnQ	581455	582189	+	peptide ABC transporter ATP-binding protein	similar to ATP-binding component of ABC transporters	gene	gene571	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02860
HSISS4_RS02865	HSISS4_00526		HSISS4_RS02865	582361	582837	+	iron transporter FeoA		gene	gene572	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02865
HSISS4_RS02870	HSISS4_00527		HSISS4_RS02870	582834	584972	+	ferrous iron transporter B		gene	gene573	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02870
HSISS4_RS02875	HSISS4_00529		HSISS4_RS02875	585285	586061	+	lysophospholipase		gene	gene574	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02875
HSISS4_RS02880	HSISS4_00530		HSISS4_RS02880	586211	587065	+	bifunctional 5%2C10-methylene-tetrahydrofolate dehydrogenase/5%2C10-methylene-tetrahydrofolate cyclohydrolase	catalyzes the formation of 5%2C10-methenyltetrahydrofolate from 5%2C10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5%2C10-methenyltetrahydrofolate	gene	gene575	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02880
HSISS4_RS02885	HSISS4_00531		HSISS4_RS02885	587069	587905	+	NADPH-hydrate epimerase		gene	gene576	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02885
HSISS4_RS02890	HSISS4_00532		HSISS4_RS02890	588027	590141	+	hypothetical protein		gene	gene577	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02890
HSISS4_RS02895	HSISS4_00533		HSISS4_RS02895	590282	590878	+	recombination protein RecR		gene	gene578	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02895
HSISS4_RS02900	HSISS4_00534		HSISS4_RS02900	590982	591821	+	transcription antiterminator BglG		gene	gene579	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02900
HSISS4_RS02905	HSISS4_00535		HSISS4_RS02905	592031	592528	+	rRNA maturation RNase YbeY		gene	gene580	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02905
HSISS4_RS02910	HSISS4_00536		HSISS4_RS02910	592509	592913	+	UDP kinase		gene	gene581	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02910
HSISS4_RS02915	HSISS4_00537	era	era	592936	593835	+	GTPase Era	Era%3B Escherichia coli Ras-like protein%3B Bex%3B Bacillus Era-complementing segment%3B essential protein in Escherichia coli that is involved in many cellular processes%3B GTPase%3B binds the cell membrane through apparent C-terminal domain%3B mutants are arrested during the cell cycle%3B Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome	gene	gene582	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02915
HSISS4_RS02920	HSISS4_00538		HSISS4_RS02920	593880	594701	+	formamidopyrimidine-DNA glycosylase		gene	gene583	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02920
HSISS4_RS02925	HSISS4_00539		HSISS4_RS02925	594698	595291	+	dephospho-CoA kinase		gene	gene584	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02925
HSISS4_RS02930	HSISS4_00540		HSISS4_RS02930	595342	596565	+	multidrug resistance efflux pump PmrA		gene	gene585	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02930
HSISS4_RS02935	HSISS4_00541		HSISS4_RS02935	596747	596983	+	preprotein translocase subunit SecG		gene	gene586	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02935
HSISS4_RS02940	HSISS4_00542		HSISS4_RS02940	597046	599499	+	3'-to-5' exoribonuclease RNase R		gene	gene587	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02940
HSISS4_RS02945	HSISS4_00543		HSISS4_RS02945	599521	599985	+	SsrA-binding protein		gene	gene588	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02945
HSISS4_RS02950	HSISS4_00544		HSISS4_RS02950	600132	601538	+	peptidyl-prolyl cis-trans isomerase		gene	gene589	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02950
HSISS4_RS02955	HSISS4_00545		HSISS4_RS02955	601540	601908	+	hypothetical protein		gene	gene590	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02955
HSISS4_RS02960	HSISS4_00546		HSISS4_RS02960	602005	603087	-	dipeptidase		gene	gene591	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02960
HSISS4_RS02965	HSISS4_00547		HSISS4_RS02965	603400	604401	+	catabolite control protein A		gene	gene592	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02965
HSISS4_RS02970	HSISS4_00548		HSISS4_RS02970	604461	605528	+	hypothetical protein		gene	gene593	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02970
HSISS4_RS02975	HSISS4_00549		HSISS4_RS02975	605541	606656	+	glycerate kinase		gene	gene594	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02975
HSISS4_RS02980	HSISS4_00550		HSISS4_RS02980	606687	607142	-	hypothetical protein		gene	gene595	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02980
HSISS4_RS02985	HSISS4_00551		HSISS4_RS02985	607348	608652	+	phosphopyruvate hydratase		gene	gene596	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02985
HSISS4_RS02990	HSISS4_00552		HSISS4_RS02990	608802	608987	-	hypothetical protein		gene	gene597	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02990
HSISS4_RS02995	HSISS4_00553		HSISS4_RS02995	609162	611348	-	alkaline phosphatase		gene	gene598	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS02995
HSISS4_RS03000	HSISS4_00554		HSISS4_RS03000	611510	612673	+	SAM-dependent methyltransferase		gene	gene599	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03000
HSISS4_RS03005	HSISS4_00555	aroD	aroD	612670	613347	+	3-dehydroquinase	catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis	gene	gene600	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03005
HSISS4_RS03010	HSISS4_00556		HSISS4_RS03010	613337	614194	+	shikimate dehydrogenase		gene	gene601	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03010
HSISS4_RS03015	HSISS4_00557		HSISS4_RS03015	614207	615274	+	3-dehydroquinate synthase		gene	gene602	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03015
HSISS4_RS03020	HSISS4_00558		HSISS4_RS03020	615275	616441	+	chorismate synthase	catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis	gene	gene603	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03020
HSISS4_RS03025	HSISS4_00559		HSISS4_RS03025	616471	617577	+	prephenate dehydrogenase		gene	gene604	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03025
HSISS4_RS03030	HSISS4_00560		HSISS4_RS03030	617587	617925	+	hypothetical protein		gene	gene605	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03030
HSISS4_RS03035	HSISS4_00561		HSISS4_RS03035	618014	618964	+	L-lactate dehydrogenase		gene	gene606	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03035
HSISS4_RS03040	HSISS4_00562		HSISS4_RS03040	619045	620328	+	3-phosphoshikimate 1-carboxyvinyltransferase		gene	gene607	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03040
HSISS4_RS03045	HSISS4_00563		HSISS4_RS03045	620321	620812	+	shikimate kinase		gene	gene608	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03045
HSISS4_RS03050	HSISS4_00564		HSISS4_RS03050	620803	621627	+	prephenate dehydratase	catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis	gene	gene609	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03050
HSISS4_RS03055	HSISS4_00565		HSISS4_RS03055	621639	623060	+	Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr%2C subfamily F1		gene	gene610	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03055
HSISS4_RS03060	HSISS4_00566		HSISS4_RS03060	623075	624013	-	exfoliative exotoxin B		gene	gene611	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03060
HSISS4_RS03065	HSISS4_00567		HSISS4_RS03065	624030	625094	-	butyryl-CoA dehydrogenase		gene	gene612	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03065
HSISS4_RS03070	HSISS4_00568		HSISS4_RS03070	625134	625682	-	alkylhydroperoxidase		gene	gene613	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03070
HSISS4_RS03075	HSISS4_00569		HSISS4_RS03075	625897	627252	+	RNA methyltransferase TrmA family		gene	gene614	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03075
HSISS4_RS03080	HSISS4_00570		HSISS4_RS03080	627642	627812	+	DNA recombinase		gene	gene615	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03080
HSISS4_RS03085	HSISS4_00571		HSISS4_RS03085	628198	629415	+	macrolide efflux MFS transporter Mef(A)		gene	gene616	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03085
HSISS4_RS03090	HSISS4_00572		HSISS4_RS03090	629535	630998	+	Msr family ABC-F type ribosomal protection protein		gene	gene617	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03090
HSISS4_RS03095	HSISS4_00573		HSISS4_RS03095	631116	631415	-	hypothetical protein		gene	gene618	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03095
HSISS4_RS03100	HSISS4_00574		HSISS4_RS03100	631402	631770	-	hypothetical protein		gene	gene619	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03100
HSISS4_RS03105	HSISS4_00575		HSISS4_RS03105	631783	632118	-	hypothetical protein		gene	gene620	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03105
HSISS4_RS03110	HSISS4_00576		HSISS4_RS03110	632115	632360	-	hypothetical protein		gene	gene621	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03110
HSISS4_RS03115	HSISS4_RS03115		HSISS4_RS03115	632357	632545	-	type VI secretion protein ImpB		gene	gene622	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03115
HSISS4_RS03120	HSISS4_RS03120		HSISS4_RS03120	633238	634071	+	dihydroorotate dehydrogenase	internal stop	gene	gene623	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03120
HSISS4_RS03125	HSISS4_00579		HSISS4_RS03125	634086	634448	+	transcriptional regulator		gene	gene624	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03125
HSISS4_RS03130	HSISS4_00580		HSISS4_RS03130	634432	636519	+	cadmium transporter		gene	gene625	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03130
HSISS4_RS03135	HSISS4_00582		HSISS4_RS03135	636734	637510	+	alpha/beta hydrolase		gene	gene626	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03135
HSISS4_RS03140	HSISS4_00583		HSISS4_RS03140	637543	638280	+	hypothetical protein		gene	gene627	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03140
HSISS4_RS03145	HSISS4_00584		HSISS4_RS03145	638422	639594	-	hypothetical protein		gene	gene628	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03145
HSISS4_RS03150	HSISS4_00585		HSISS4_RS03150	639815	640657	-	fatty acid-binding protein DegV		gene	gene629	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03150
HSISS4_RS03155	HSISS4_00586		HSISS4_RS03155	640783	641352	+	TetR family transcriptional regulator		gene	gene630	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03155
HSISS4_RS03160	HSISS4_00587		HSISS4_RS03160	641390	642025	+	copper homeostasis protein CutC		gene	gene631	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03160
HSISS4_RS03165	HSISS4_00588		HSISS4_RS03165	642148	642420	+	hypothetical protein		gene	gene632	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03165
HSISS4_RS03170	HSISS4_00589		HSISS4_RS03170	642539	643786	+	lipoprotein precursor		gene	gene633	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03170
HSISS4_RS03175	HSISS4_00590		HSISS4_RS03175	643919	644758	+	hypothetical protein		gene	gene634	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03175
HSISS4_RS03180	HSISS4_00591		HSISS4_RS03180	644807	645553	+	hypothetical protein		gene	gene635	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03180
HSISS4_RS03185	HSISS4_00592		HSISS4_RS03185	645728	646771	+	Vitamin B12 ABC transporter permease BtuC		gene	gene636	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03185
HSISS4_RS03190	HSISS4_00593		HSISS4_RS03190	646776	647531	+	ABC transporter		gene	gene637	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03190
HSISS4_RS03195	HSISS4_00594		HSISS4_RS03195	647552	648568	+	Vitamin B12 ABC transporter B12-binding protein BtuF		gene	gene638	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03195
HSISS4_RS03200	HSISS4_00595		HSISS4_RS03200	648549	649238	+	alpha/beta hydrolase		gene	gene639	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03200
HSISS4_RS03205	HSISS4_00596		HSISS4_RS03205	649532	650413	-	lipid kinase		gene	gene640	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03205
HSISS4_RS03210	HSISS4_00597		HSISS4_RS03210	650517	651542	-	hypothetical protein		gene	gene641	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03210
HSISS4_RS03215	HSISS4_00598		HSISS4_RS03215	652242	652481	+	membrane protein		gene	gene642	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03215
HSISS4_RS03220	HSISS4_00599		HSISS4_RS03220	652738	652941	+	hypothetical protein		gene	gene643	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03220
HSISS4_RS03225	HSISS4_00600		HSISS4_RS03225	653509	654849	+	dihydrolipoamide dehydrogenase		gene	gene644	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03225
HSISS4_RS03230	HSISS4_00601		HSISS4_RS03230	654954	656027	+	acetoin dehydrogenase E1 component alpha-subunit		gene	gene645	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03230
HSISS4_RS03235	HSISS4_00602		HSISS4_RS03235	656044	657075	+	pyruvate dehydrogenase subunit beta		gene	gene646	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03235
HSISS4_RS03240	HSISS4_00603		HSISS4_RS03240	657086	658315	+	dihydrolipoamide acetyltransferase		gene	gene647	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03240
HSISS4_RS03245	HSISS4_00604		HSISS4_RS03245	658587	658898	+	hypothetical protein		gene	gene648	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03245
HSISS4_RS03250	HSISS4_00605		HSISS4_RS03250	658989	659738	+	CAAX amino protease		gene	gene649	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03250
HSISS4_RS03255	HSISS4_00606		HSISS4_RS03255	659985	660182	-	hypothetical protein		gene	gene650	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03255
HSISS4_RS03260	HSISS4_00607		HSISS4_RS03260	660282	660701	-	hypothetical protein		gene	gene651	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03260
HSISS4_RS03265	HSISS4_00608		HSISS4_RS03265	660876	661268	+	hypothetical protein		gene	gene652	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03265
HSISS4_RS03270	HSISS4_00609		HSISS4_RS03270	661265	661627	+	hypothetical protein		gene	gene653	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03270
HSISS4_RS03275	HSISS4_00610		HSISS4_RS03275	661640	662017	+	hypothetical protein		gene	gene654	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03275
HSISS4_RS03280	HSISS4_00611		HSISS4_RS03280	662022	662384	+	hypothetical protein		gene	gene655	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03280
HSISS4_RS03285	HSISS4_00612		HSISS4_RS03285	662488	663099	+	hypothetical protein		gene	gene656	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03285
HSISS4_RS03290	HSISS4_00613		HSISS4_RS03290	663126	663767	+	hypothetical protein		gene	gene657	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03290
HSISS4_RS03295	HSISS4_00614		HSISS4_RS03295	663863	664477	+	hypothetical protein		gene	gene658	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03295
HSISS4_RS03300	HSISS4_00615		HSISS4_RS03300	664727	666238	+	sodium-independent anion transporter		gene	gene659	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03300
HSISS4_RS03305	HSISS4_00616		HSISS4_RS03305	666291	667106	-	phosphate ABC transporter substrate-binding protein		gene	gene660	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03305
HSISS4_RS03310	HSISS4_00617		HSISS4_RS03310	667106	668008	-	permease		gene	gene661	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03310
HSISS4_RS03315	HSISS4_00619		HSISS4_RS03315	668424	670556	+	RNA-binding transcriptional accessory protein		gene	gene662	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03315
HSISS4_RS03320	HSISS4_00620		HSISS4_RS03320	670543	670983	+	SprT family protein		gene	gene663	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03320
HSISS4_RS03325	HSISS4_00621		HSISS4_RS03325	671049	671312	+	membrane protein		gene	gene664	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03325
HSISS4_RS03330	HSISS4_00622		HSISS4_RS03330	671439	672368	+	HPr kinase/phosphorylase		gene	gene665	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03330
HSISS4_RS03335	HSISS4_00623		HSISS4_RS03335	672368	673159	+	prolipoprotein diacylglyceryl transferase	transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein	gene	gene666	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03335
HSISS4_RS03340	HSISS4_00624		HSISS4_RS03340	673284	673682	+	chemotaxis protein		gene	gene667	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03340
HSISS4_RS03345	HSISS4_00625		HSISS4_RS03345	673695	674135	+	hypothetical protein		gene	gene668	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03345
HSISS4_RS03350	HSISS4_00626		HSISS4_RS03350	674189	674485	-	hypothetical protein		gene	gene669	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03350
HSISS4_RS03355	HSISS4_00627		HSISS4_RS03355	674724	675653	+	peptidase U32		gene	gene670	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03355
HSISS4_RS03360	HSISS4_00628		HSISS4_RS03360	675749	677035	+	peptidase U32		gene	gene671	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03360
HSISS4_RS03365	HSISS4_00630		HSISS4_RS03365	677525	678781	+	transposase		gene	gene672	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03365
HSISS4_RS03370	HSISS4_00631		HSISS4_RS03370	678818	679357	-	Substrate-specific component BioY of biotin ECF transporter		gene	gene673	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03370
HSISS4_RS03375	HSISS4_00632		HSISS4_RS03375	679498	679737	-	hypothetical protein		gene	gene674	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03375
HSISS4_RS03380	HSISS4_00633		HSISS4_RS03380	679862	680074	+	hypothetical protein		gene	gene675	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03380
HSISS4_RS03385	HSISS4_00634		HSISS4_RS03385	680108	681442	-	manganese transporter MntH		gene	gene676	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03385
HSISS4_RS03390	HSISS4_00635		HSISS4_RS03390	681640	681948	+	hypothetical protein		gene	gene677	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03390
HSISS4_RS03395	HSISS4_00636		HSISS4_RS03395	682050	682439	+	DNA mismatch repair protein MutT		gene	gene678	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03395
HSISS4_RS03400	HSISS4_00637		HSISS4_RS03400	682462	685347	-	helicase		gene	gene679	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03400
HSISS4_RS03405	HSISS4_00638		HSISS4_RS03405	685625	686170	-	hypothetical protein		gene	gene680	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03405
HSISS4_RS03410	HSISS4_00639		HSISS4_RS03410	686224	687714	-	lysine--tRNA ligase		gene	gene681	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03410
HSISS4_RS03415	HSISS4_00640		HSISS4_RS03415	687942	689264	+	hypothetical protein		gene	gene682	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03415
HSISS4_RS03420	HSISS4_00641		HSISS4_RS03420	689278	689757	+	hypothetical protein		gene	gene683	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03420
HSISS4_RS03425	HSISS4_00642		HSISS4_RS03425	690078	690980	+	haloacid dehalogenase		gene	gene684	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03425
HSISS4_RS03430	HSISS4_00643		HSISS4_RS03430	691039	691458	+	hypothetical protein		gene	gene685	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03430
HSISS4_RS03435	HSISS4_00644		HSISS4_RS03435	691558	692196	-	phosphoglycerate mutase		gene	gene686	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03435
HSISS4_RS03440	HSISS4_00645		HSISS4_RS03440	692199	692672	-	aminoacyl-tRNA deacylase		gene	gene687	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03440
HSISS4_RS03445	HSISS4_00646		HSISS4_RS03445	692785	693687	-	N-acetylmuramoyl-L-alanine amidase		gene	gene688	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03445
HSISS4_RS03450	HSISS4_00647		HSISS4_RS03450	693878	694267	-	Na+ driven multidrug efflux pump		gene	gene689	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03450
HSISS4_RS03455	HSISS4_00648		HSISS4_RS03455	694419	695261	+	hypothetical protein		gene	gene690	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03455
HSISS4_RS03460	HSISS4_00649		HSISS4_RS03460	695298	695924	-	hypothetical protein		gene	gene691	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03460
HSISS4_RS03465	HSISS4_00650		HSISS4_RS03465	696034	697191	+	hypothetical protein		gene	gene692	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03465
HSISS4_RS03470	HSISS4_00651		HSISS4_RS03470	697223	697990	+	oxidoreductase short-chain dehydrogenase/reductase family		gene	gene693	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03470
HSISS4_RS03475	HSISS4_00653		HSISS4_RS03475	698249	701239	+	type I restriction endonuclease subunit R		gene	gene694	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03475
HSISS4_RS03480	HSISS4_00654		HSISS4_RS03480	701261	702403	+	hypothetical protein		gene	gene695	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03480
HSISS4_RS03485	HSISS4_00655		HSISS4_RS03485	702570	703277	+	hypothetical protein		gene	gene696	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03485
HSISS4_RS03490	HSISS4_00656		HSISS4_RS03490	703475	704629	+	hypothetical protein		gene	gene697	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03490
HSISS4_RS03495	HSISS4_00657		HSISS4_RS03495	704645	705559	+	hypothetical protein		gene	gene698	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03495
HSISS4_RS03500	HSISS4_00658		HSISS4_RS03500	705771	706136	+	phage-related protein		gene	gene699	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03500
HSISS4_RS03505	HSISS4_00659		HSISS4_RS03505	706126	706419	+	transcriptional regulator		gene	gene700	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03505
HSISS4_RS03510	HSISS4_00660		HSISS4_RS03510	706441	708042	+	type I restriction endonuclease subunit M		gene	gene701	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03510
HSISS4_RS03515	HSISS4_00661		HSISS4_RS03515	708121	709056	+	hypothetical protein		gene	gene702	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03515
HSISS4_RS03520	HSISS4_00662		HSISS4_RS03520	709589	713041	+	alpha-1%2C3-glucanase		gene	gene703	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03520
HSISS4_RS03525	HSISS4_00663		HSISS4_RS03525	713185	714189	+	nuclease 2 Mitogenic factor 2		gene	gene704	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03525
HSISS4_RS03530	HSISS4_00664		HSISS4_RS03530	714340	714900	+	membrane protein		gene	gene705	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03530
HSISS4_RS03535	HSISS4_00665		HSISS4_RS03535	714902	715801	+	protease HtpX	metalloprotease	gene	gene706	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03535
HSISS4_RS03540	HSISS4_00666		HSISS4_RS03540	715852	716499	-	Mn-dependent transcriptional regulator MntR		gene	gene707	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03540
HSISS4_RS03545	HSISS4_00667		HSISS4_RS03545	716579	717505	-	manganese ABC transporter substrate-binding protein		gene	gene708	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03545
HSISS4_RS03550	HSISS4_00668		HSISS4_RS03550	717525	718364	-	Manganese ABC transporter innermembrane permease SitD		gene	gene709	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03550
HSISS4_RS03555	HSISS4_00669		HSISS4_RS03555	718354	719082	-	manganese ABC transporter ATP-binding protein		gene	gene710	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03555
HSISS4_RS03560	HSISS4_00670		HSISS4_RS03560	719372	719845	+	substrate-specific component CbrT of cobalamin ECF transporter		gene	gene711	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03560
HSISS4_RS03565	HSISS4_00671		HSISS4_RS03565	719842	720237	+	lipoprotein component cobalamin ECF transporter		gene	gene712	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03565
HSISS4_RS03570	HSISS4_00672		HSISS4_RS03570	720412	723234	+	phosphoenolpyruvate carboxylase		gene	gene713	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03570
HSISS4_RS03575	HSISS4_00673		HSISS4_RS03575	723302	724336	+	DNA polymerase III subunit delta		gene	gene714	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03575
HSISS4_RS03580	HSISS4_00674		HSISS4_RS03580	724432	725037	+	superoxide dismutase		gene	gene715	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03580
HSISS4_RS03585	HSISS4_00675		HSISS4_RS03585	725537	726532	+	D-Ala-D-Ala carboxypeptidase		gene	gene716	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03585
HSISS4_RS03590	HSISS4_00677		HSISS4_RS03590	727330	727851	+	DNA starvation/stationary phase protection protein		gene	gene717	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03590
HSISS4_RS03595	HSISS4_00678		HSISS4_RS03595	727939	728376	+	transcriptional repressor		gene	gene718	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03595
HSISS4_RS03600	HSISS4_00679		HSISS4_RS03600	728479	728685	+	hypothetical protein		gene	gene719	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03600
HSISS4_RS03605	HSISS4_00680		HSISS4_RS03605	728678	729646	+	glucokinase		gene	gene720	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03605
HSISS4_RS03610	HSISS4_00681		HSISS4_RS03610	729791	731641	+	GTP-binding protein		gene	gene721	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03610
HSISS4_RS03615	HSISS4_00682		HSISS4_RS03615	731661	731930	+	membrane protein		gene	gene722	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03615
HSISS4_RS03620	HSISS4_00683	murD	murD	732058	733410	+	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation	gene	gene723	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03620
HSISS4_RS03625	HSISS4_00684		HSISS4_RS03625	733414	734484	+	UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase		gene	gene724	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03625
HSISS4_RS03630	HSISS4_00685		HSISS4_RS03630	734494	735636	+	cell division protein FtsQ		gene	gene725	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03630
HSISS4_RS03635	HSISS4_00686		HSISS4_RS03635	735763	737139	+	cell division protein FtsA		gene	gene726	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03635
HSISS4_RS03640	HSISS4_00687		HSISS4_RS03640	737168	738490	+	cell division protein FtsZ		gene	gene727	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03640
HSISS4_RS03645	HSISS4_00688		HSISS4_RS03645	738493	739176	+	YggS family pyridoxal phosphate enzyme		gene	gene728	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03645
HSISS4_RS03650	HSISS4_00689		HSISS4_RS03650	739181	739765	+	FtsZ-interacting protein related to cell division		gene	gene729	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03650
HSISS4_RS03655	HSISS4_00690		HSISS4_RS03655	739769	740026	+	membrane protein		gene	gene730	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03655
HSISS4_RS03660	HSISS4_00691		HSISS4_RS03660	740026	740829	+	hypothetical protein		gene	gene731	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03660
HSISS4_RS03665	HSISS4_00692		HSISS4_RS03665	740882	741757	+	cell division protein DivIVA		gene	gene732	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03665
HSISS4_RS03670	HSISS4_00693	ileS	ileS	742004	744802	+	isoleucine--tRNA ligase	IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme	gene	gene733	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03670
HSISS4_RS03675	HSISS4_00694		HSISS4_RS03675	744894	745853	-	ribonucleotide reductase of class Ib (aerobic)%2C subunit beta	B2 or R2 protein%3B type 1b enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdE	gene	gene734	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03675
HSISS4_RS03680	HSISS4_00695		HSISS4_RS03680	746011	748170	-	ribonucleotide-diphosphate reductase	Catalyzes the rate-limiting step in dNTP synthesis	gene	gene735	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03680
HSISS4_RS03685	HSISS4_00696		HSISS4_RS03685	748261	748485	-	NrdH-redoxin		gene	gene736	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03685
HSISS4_RS03690	HSISS4_00697		HSISS4_RS03690	748819	751482	+	aconitate hydratase	Catalyzes the conversion of citrate to isocitrate	gene	gene737	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03690
HSISS4_RS03695	HSISS4_00698		HSISS4_RS03695	751484	752608	+	citrate synthase	catalyzes the formation of citrate from acetyl-CoA and oxaloacetate	gene	gene738	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03695
HSISS4_RS03700	HSISS4_00699		HSISS4_RS03700	752622	753797	+	isocitrate dehydrogenase	Converts isocitrate to alpha ketoglutarate	gene	gene739	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03700
HSISS4_RS03705	HSISS4_00700		HSISS4_RS03705	754059	754322	+	phosphocarrier protein HPr		gene	gene740	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03705
HSISS4_RS03710	HSISS4_00701		HSISS4_RS03710	754327	756060	+	phosphoenolpyruvate--protein phosphotransferase	Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system	gene	gene741	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03710
HSISS4_RS03715	HSISS4_00702		HSISS4_RS03715	756279	757712	+	glyceraldehyde-3-phosphate dehydrogenase		gene	gene742	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03715
HSISS4_RS03720	HSISS4_00703		HSISS4_RS03720	757828	758655	+	esterase		gene	gene743	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03720
HSISS4_RS03725	HSISS4_00704		HSISS4_RS03725	758703	759443	+	esterase		gene	gene744	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03725
HSISS4_RS03730	HSISS4_00705		HSISS4_RS03730	759490	760653	+	hypothetical protein		gene	gene745	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03730
HSISS4_RS03735	HSISS4_00706		HSISS4_RS03735	760706	761788	-	RNA helicase		gene	gene746	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03735
HSISS4_RS03740	HSISS4_00707		HSISS4_RS03740	761880	762515	+	uridine kinase	functions in pyrimidine salvage%3B pyrimidine ribonucleoside kinase%3B phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor	gene	gene747	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03740
HSISS4_RS03745	HSISS4_00708		HSISS4_RS03745	762552	764471	+	ABC transporter ATP-binding protein		gene	gene748	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03745
HSISS4_RS03750	HSISS4_00709		HSISS4_RS03750	764561	764821	+	hypothetical protein		gene	gene749	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03750
HSISS4_RS03755	HSISS4_00710		HSISS4_RS03755	765017	765736	+	oxidoreductase		gene	gene750	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03755
HSISS4_RS03760	HSISS4_00711		HSISS4_RS03760	765733	768288	+	hypothetical protein		gene	gene751	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03760
HSISS4_RS03765	HSISS4_00712		HSISS4_RS03765	768342	769130	-	amidotransferase		gene	gene752	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03765
HSISS4_RS03770	HSISS4_00713		HSISS4_RS03770	769130	770473	-	amino acid ligase		gene	gene753	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03770
HSISS4_RS03775	HSISS4_00714		HSISS4_RS03775	770575	771426	+	membrane protein		gene	gene754	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03775
HSISS4_RS03780	HSISS4_00715		HSISS4_RS03780	771423	772388	+	hypothetical protein		gene	gene755	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03780
HSISS4_RS03785	HSISS4_00716	glmM	glmM	772609	773961	+	phosphoglucosamine mutase	catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	gene	gene756	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03785
HSISS4_RS03790	HSISS4_00717		HSISS4_RS03790	773964	774404	+	sugar translocase		gene	gene757	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03790
HSISS4_RS03795	HSISS4_00718		HSISS4_RS03795	774503	775189	+	tRNA-m1A22 methylase		gene	gene758	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03795
HSISS4_RS03800	HSISS4_00719		HSISS4_RS03800	775179	775967	+	Nif3-like dinuclear metal center hexameric protein		gene	gene759	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03800
HSISS4_RS03805	HSISS4_00720		HSISS4_RS03805	775980	776807	+	divalent heavy-metal cations transporter		gene	gene760	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03805
HSISS4_RS03810	HSISS4_00721		HSISS4_RS03810	776874	777962	+	glycine/D-amino acid oxidase family		gene	gene761	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03810
HSISS4_RS03815	HSISS4_00722		HSISS4_RS03815	778147	779493	+	glucan-binding protein		gene	gene762	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03815
HSISS4_RS03820	HSISS4_00723		HSISS4_RS03820	779706	780575	+	glucose-1-phosphate thymidylyltransferase		gene	gene763	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03820
HSISS4_RS03825	HSISS4_00724		HSISS4_RS03825	780575	781168	+	dTDP-4-dehydrorhamnose 3%2C5-epimerase		gene	gene764	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03825
HSISS4_RS03830	HSISS4_00725		HSISS4_RS03830	781369	782415	+	dTDP-glucose 4%2C6-dehydratase		gene	gene765	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03830
HSISS4_RS03835	HSISS4_00726		HSISS4_RS03835	782480	783556	+	hypothetical protein		gene	gene766	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03835
HSISS4_RS03840	HSISS4_00727		HSISS4_RS03840	783759	784499	+	hypothetical protein		gene	gene767	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03840
HSISS4_RS03845	HSISS4_00728		HSISS4_RS03845	784594	785730	+	coproporphyrinogen III oxidase	catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III	gene	gene768	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03845
HSISS4_RS03850	HSISS4_00729		HSISS4_RS03850	785731	786474	+	acyl-ACP thioesterase		gene	gene769	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03850
HSISS4_RS03855	HSISS4_00730		HSISS4_RS03855	786476	787249	+	NagD-like phosphatase		gene	gene770	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03855
HSISS4_RS03860	HSISS4_00731		HSISS4_RS03860	787239	787883	+	integral membrane protein		gene	gene771	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03860
HSISS4_RS03865	HSISS4_00732		HSISS4_RS03865	787892	788626	+	hypothetical protein		gene	gene772	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03865
HSISS4_RS03870	HSISS4_00733		HSISS4_RS03870	788788	789711	+	exopolysaccharide biosynthesis protein		gene	gene773	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03870
HSISS4_RS03875	HSISS4_00734		HSISS4_RS03875	789692	790081	+	membrane protein		gene	gene774	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03875
HSISS4_RS03880	HSISS4_00735		HSISS4_RS03880	790831	791883	+	histidinol-phosphate transaminase	catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis	gene	gene775	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03880
HSISS4_RS03885	HSISS4_00736		HSISS4_RS03885	791880	792860	+	ATP phosphoribosyltransferase regulatory subunit		gene	gene776	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03885
HSISS4_RS03890	HSISS4_00737		HSISS4_RS03890	792853	793503	+	ATP phosphoribosyltransferase		gene	gene777	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03890
HSISS4_RS03895	HSISS4_00738		HSISS4_RS03895	793500	794783	+	histidinol dehydrogenase		gene	gene778	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03895
HSISS4_RS03900	HSISS4_00739	hisB	hisB	794803	795387	+	imidazoleglycerol-phosphate dehydratase	catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis	gene	gene779	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03900
HSISS4_RS03905	HSISS4_00740	hisH	hisH	795384	795992	+	imidazole glycerol phosphate synthase subunit HisH	with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide	gene	gene780	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03905
HSISS4_RS03910	HSISS4_00741		HSISS4_RS03910	796041	796760	+	1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase		gene	gene781	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03910
HSISS4_RS03915	HSISS4_00742		HSISS4_RS03915	796762	797520	+	imidazole glycerol phosphate synthase cyclase subunit	catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]-1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamideribonucleotide and glutamate%3B the HisF subunit acts as a cyclase	gene	gene782	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03915
HSISS4_RS03920	HSISS4_00743		HSISS4_RS03920	797517	797855	+	phosphoribosyl-AMP cyclohydrolase		gene	gene783	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03920
HSISS4_RS03925	HSISS4_00744		HSISS4_RS03925	797864	798178	+	phosphoribosyl-ATP pyrophosphatase		gene	gene784	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03925
HSISS4_RS03930	HSISS4_00745		HSISS4_RS03930	798406	799305	+	hypothetical protein		gene	gene785	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03930
HSISS4_RS03935	HSISS4_00746		HSISS4_RS03935	799406	800089	-	hypothetical protein		gene	gene786	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03935
HSISS4_RS03940	HSISS4_00747		HSISS4_RS03940	800082	800861	-	VTC domain-containing protein		gene	gene787	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03940
HSISS4_RS03945	HSISS4_00748		HSISS4_RS03945	801186	802451	+	hypothetical protein		gene	gene788	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03945
HSISS4_RS03950	HSISS4_00749		HSISS4_RS03950	802485	803507	+	glycosyl transferase		gene	gene789	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03950
HSISS4_RS03955	HSISS4_00750		HSISS4_RS03955	803774	808255	+	glucosyltransferase		gene	gene790	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03955
HSISS4_RS03960	HSISS4_00751		HSISS4_RS03960	808681	813039	+	glucosyltransferase		gene	gene791	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03960
HSISS4_RS03965	HSISS4_RS03965		HSISS4_RS03965	813085	813264	+	capsular biosynthesis protein CpsL		gene	gene792	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03965
HSISS4_RS03970	HSISS4_00753		HSISS4_RS03970	813410	813640	+	hypothetical protein		gene	gene793	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03970
HSISS4_RS03975	HSISS4_00754		HSISS4_RS03975	813882	814145	+	hypothetical protein		gene	gene794	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03975
HSISS4_RS03980	HSISS4_00755		HSISS4_RS03980	814379	814918	-	3-methyladenine DNA glycosylase	constitutive%2C catalyzes the hydrolysis of alkylated DNA%2C releasing 3-methyladenine	gene	gene795	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03980
HSISS4_RS03985	HSISS4_RS03985		HSISS4_RS03985	814970	816016	+	transposase	internal stop	gene	gene796	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03985
HSISS4_RS03990	HSISS4_00758		HSISS4_RS03990	816509	821308	+	glucosyltransferase		gene	gene797	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03990
HSISS4_RS03995	HSISS4_00759		HSISS4_RS03995	821452	822879	+	hypothetical protein		gene	gene798	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS03995
HSISS4_RS04000	HSISS4_00760		HSISS4_RS04000	822999	824237	+	GTP-binding protein		gene	gene799	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04000
HSISS4_RS04005	HSISS4_00761		HSISS4_RS04005	824230	824871	+	hypothetical protein		gene	gene800	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04005
HSISS4_RS04010	HSISS4_00762		HSISS4_RS04010	824903	825832	+	ribonuclease Z		gene	gene801	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04010
HSISS4_RS04015	HSISS4_00763		HSISS4_RS04015	825832	826599	+	short-chain dehydrogenase		gene	gene802	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04015
HSISS4_RS04020	HSISS4_00764		HSISS4_RS04020	826810	827214	+	GNAT family acetyltransferase		gene	gene803	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04020
HSISS4_RS04025	HSISS4_00765		HSISS4_RS04025	827523	829724	+	single-stranded DNA exonuclease		gene	gene804	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04025
HSISS4_RS04030	HSISS4_00766		HSISS4_RS04030	829845	830363	+	adenine phosphoribosyltransferase		gene	gene805	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04030
HSISS4_RS04035	HSISS4_00767		HSISS4_RS04035	830536	831480	+	homoserine O-succinyltransferase		gene	gene806	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04035
HSISS4_RS04040	HSISS4_00768		HSISS4_RS04040	831552	832250	+	DNA replication protein DnaD		gene	gene807	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04040
HSISS4_RS04045	HSISS4_00769		HSISS4_RS04045	832250	832894	+	endonuclease III		gene	gene808	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04045
HSISS4_RS04050	HSISS4_00770		HSISS4_RS04050	833022	833783	+	hypothetical protein		gene	gene809	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04050
HSISS4_RS04055	HSISS4_00771		HSISS4_RS04055	833970	835298	+	exodeoxyribonuclease VII large subunit		gene	gene810	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04055
HSISS4_RS04060	HSISS4_00772		HSISS4_RS04060	835288	835503	+	exodeoxyribonuclease VII small subunit		gene	gene811	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04060
HSISS4_RS04065	HSISS4_00773		HSISS4_RS04065	835503	836375	+	geranyltranstransferase		gene	gene812	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04065
HSISS4_RS04070	HSISS4_00774		HSISS4_RS04070	836368	837195	+	cell division protein FtsJ		gene	gene813	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04070
HSISS4_RS04075	HSISS4_00775		HSISS4_RS04075	837182	837628	+	ArgR family transcriptional regulator		gene	gene814	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04075
HSISS4_RS04080	HSISS4_00776		HSISS4_RS04080	837637	839307	+	DNA repair protein RecN		gene	gene815	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04080
HSISS4_RS04085	HSISS4_00777		HSISS4_RS04085	839377	840219	+	fatty acid-binding protein DegV		gene	gene816	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04085
HSISS4_RS04090	HSISS4_00778		HSISS4_RS04090	840212	841087	+	lipase/acylhydrolase		gene	gene817	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04090
HSISS4_RS04095	HSISS4_00779		HSISS4_RS04095	841080	841652	+	hypothetical protein		gene	gene818	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04095
HSISS4_RS04100	HSISS4_00780		HSISS4_RS04100	841789	842064	+	DNA-binding protein HU		gene	gene819	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04100
HSISS4_RS04105	HSISS4_00781		HSISS4_RS04105	842124	842324	+	hypothetical protein		gene	gene820	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04105
HSISS4_RS04110	HSISS4_00782		HSISS4_RS04110	842386	843321	-	dihydroorotate dehydrogenase	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group	gene	gene821	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04110
HSISS4_RS04115	HSISS4_00783		HSISS4_RS04115	843576	844268	+	phosphoglycerate mutase		gene	gene822	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04115
HSISS4_RS04120	HSISS4_00784		HSISS4_RS04120	844615	846171	+	2-isopropylmalate synthase		gene	gene823	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04120
HSISS4_RS04125	HSISS4_00785		HSISS4_RS04125	846190	847227	+	3-isopropylmalate dehydrogenase		gene	gene824	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04125
HSISS4_RS04130	HSISS4_RS04130		HSISS4_RS04130	847232	847513	+	membrane protein		gene	gene825	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04130
HSISS4_RS04135	HSISS4_00786		HSISS4_RS04135	847544	848935	+	3-isopropylmalate dehydratase large subunit	dehydratase component%2C catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate	gene	gene826	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04135
HSISS4_RS04140	HSISS4_00787		HSISS4_RS04140	848947	849537	+	3-isopropylmalate dehydratase small subunit		gene	gene827	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04140
HSISS4_RS04145	HSISS4_00788	dnaE	dnaE	849752	852862	+	DNA polymerase III subunit alpha	Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.	gene	gene828	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04145
HSISS4_RS04150	HSISS4_00789		HSISS4_RS04150	852956	853975	+	6-phosphofructokinase	catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis	gene	gene829	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04150
HSISS4_RS04155	HSISS4_00790		HSISS4_RS04155	854046	855548	+	pyruvate kinase	catalyzes the formation of phosphoenolpyruvate from pyruvate	gene	gene830	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04155
HSISS4_RS04160	HSISS4_00791		HSISS4_RS04160	856381	864024	+	CshA family fibrillar surface protein C		gene	gene831	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04160
HSISS4_RS04165	HSISS4_00792		HSISS4_RS04165	864208	864429	+	DUF4649 domain-containing protein		gene	gene832	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04165
HSISS4_RS04170	HSISS4_00793		HSISS4_RS04170	864566	865567	+	peptide ABC transporter substrate-binding protein		gene	gene833	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04170
HSISS4_RS04175	HSISS4_00794		HSISS4_RS04175	865577	866446	+	branched-chain amino acid ABC transporter permease		gene	gene834	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04175
HSISS4_RS04180	HSISS4_00795		HSISS4_RS04180	866443	867201	+	ABC transporter ATP-binding protein		gene	gene835	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04180
HSISS4_RS04185	HSISS4_00796		HSISS4_RS04185	867381	869042	+	ribonuclease J		gene	gene836	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04185
HSISS4_RS04190	HSISS4_00797		HSISS4_RS04190	869177	869959	+	tributyrin esterase		gene	gene837	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04190
HSISS4_RS04195	HSISS4_00798		HSISS4_RS04195	870079	870798	+	Zn-dependent protease		gene	gene838	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04195
HSISS4_RS04200	HSISS4_00799		HSISS4_RS04200	870811	871182	+	hypothetical protein		gene	gene839	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04200
HSISS4_RS04205	HSISS4_00800		HSISS4_RS04205	871268	871711	+	flavodoxin	An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group	gene	gene840	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04205
HSISS4_RS04210	HSISS4_00801		HSISS4_RS04210	871764	873299	+	Voltage-gated chloride channel family protein		gene	gene841	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04210
HSISS4_RS04215	HSISS4_00802		HSISS4_RS04215	873373	873657	+	chorismate mutase		gene	gene842	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04215
HSISS4_RS04220	HSISS4_00803		HSISS4_RS04220	873654	874880	+	hypothetical protein		gene	gene843	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04220
HSISS4_RS04225	HSISS4_00804	rplS	rplS	875008	875355	+	50S ribosomal protein L19	this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	gene	gene844	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04225
HSISS4_RS04230	HSISS4_r00058		HSISS4_RS04230	875406	875477	+	tRNA-Arg		tRNA	gene845	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04230
HSISS4_RS04235	HSISS4_00805		HSISS4_RS04235	875652	876197	-	hypothetical protein		gene	gene846	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04235
HSISS4_RS04240	HSISS4_00807		HSISS4_RS04240	876524	877435	+	tRNA dimethylallyltransferase		gene	gene847	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04240
HSISS4_RS04245	HSISS4_00808		HSISS4_RS04245	877460	877969	+	hypothetical protein		gene	gene848	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04245
HSISS4_RS04250	HSISS4_00809		HSISS4_RS04250	877969	879621	+	DNA polymerase III subunit gamma/tau	catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand%3B the tau chain serves as a scaffold to help in the dimerizaton of the alpha%2Cepsilon and theta core complex%3B the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA	gene	gene849	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04250
HSISS4_RS04255	HSISS4_00811		HSISS4_RS04255	879950	880888	-	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor		gene	gene850	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04255
HSISS4_RS04260	HSISS4_00812		HSISS4_RS04260	881168	882361	+	methionine adenosyltransferase	catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase	gene	gene851	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04260
HSISS4_RS04265	HSISS4_00813		HSISS4_RS04265	883029	884801	+	hypothetical protein		gene	gene852	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04265
HSISS4_RS04270	HSISS4_00814		HSISS4_RS04270	884798	885715	+	hypothetical protein		gene	gene853	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04270
HSISS4_RS04275	HSISS4_00815		HSISS4_RS04275	885712	887538	+	hypothetical protein		gene	gene854	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04275
HSISS4_RS04280	HSISS4_00816		HSISS4_RS04280	887561	888964	+	glycosyl transferase group 1 family protein		gene	gene855	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04280
HSISS4_RS04285	HSISS4_00817		HSISS4_RS04285	888964	890415	+	transmembrane protein		gene	gene856	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04285
HSISS4_RS04290	HSISS4_00818		HSISS4_RS04290	890412	892178	+	hypothetical protein		gene	gene857	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04290
HSISS4_RS04295	HSISS4_00819		HSISS4_RS04295	892168	892896	+	transporter		gene	gene858	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04295
HSISS4_RS04300	HSISS4_00820		HSISS4_RS04300	892945	893616	+	hypothetical protein		gene	gene859	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04300
HSISS4_RS04305	HSISS4_00821		HSISS4_RS04305	893609	895030	+	hypothetical protein		gene	gene860	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04305
HSISS4_RS04310	HSISS4_00822		HSISS4_RS04310	895045	896058	+	UDP-glucose 4-epimerase		gene	gene861	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04310
HSISS4_RS04315	HSISS4_00823		HSISS4_RS04315	896250	896486	+	membrane protein		gene	gene862	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04315
HSISS4_RS04320	HSISS4_00824		HSISS4_RS04320	896554	897825	+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation%3B gram-positive bacteria have 2 copies of MurA which are active	gene	gene863	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04320
HSISS4_RS04325	HSISS4_00825		HSISS4_RS04325	897827	898015	+	DNA-directed RNA polymerase subunit beta		gene	gene864	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04325
HSISS4_RS04330	HSISS4_00826		HSISS4_RS04330	898077	898958	+	DNA-entry nuclease (Competence-specific nuclease)		gene	gene865	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04330
HSISS4_RS04335	HSISS4_00827		HSISS4_RS04335	899036	899686	-	glutamine ABC transporter permease		gene	gene866	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04335
HSISS4_RS04340	HSISS4_00828		HSISS4_RS04340	899698	900396	-	glutamine ABC transporter permease		gene	gene867	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04340
HSISS4_RS04345	HSISS4_00829		HSISS4_RS04345	900414	901247	-	glutamate transport substrate-binding protein		gene	gene868	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04345
HSISS4_RS04350	HSISS4_00830		HSISS4_RS04350	901259	902026	-	arginine ABC transporter ATP-binding protein		gene	gene869	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04350
HSISS4_RS04355	HSISS4_00831		HSISS4_RS04355	902329	903585	+	transposase		gene	gene870	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04355
HSISS4_RS04360	HSISS4_00832		HSISS4_RS04360	903633	904283	-	glutamine ABC transporter permease		gene	gene871	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04360
HSISS4_RS04365	HSISS4_00833		HSISS4_RS04365	904295	904993	-	glutamine ABC transporter permease		gene	gene872	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04365
HSISS4_RS04370	HSISS4_00834		HSISS4_RS04370	905011	905844	-	glutamate transport substrate-binding protein		gene	gene873	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04370
HSISS4_RS04375	HSISS4_00835		HSISS4_RS04375	905854	906621	-	arginine ABC transporter ATP-binding protein		gene	gene874	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04375
HSISS4_RS04380	HSISS4_00836		HSISS4_RS04380	906906	907613	+	DNA-binding response regulator		gene	gene875	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04380
HSISS4_RS04385	HSISS4_00837		HSISS4_RS04385	907606	908946	+	sensor kinase		gene	gene876	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04385
HSISS4_RS04390	HSISS4_00838		HSISS4_RS04390	908952	909764	+	metallo-hydrolase		gene	gene877	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04390
HSISS4_RS04395	HSISS4_00839		HSISS4_RS04395	909823	910182	+	hypothetical protein		gene	gene878	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04395
HSISS4_RS04400	HSISS4_00840		HSISS4_RS04400	910234	911448	-	tRNA-dependent lipid II--L-alanine ligase		gene	gene879	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04400
HSISS4_RS04405	HSISS4_00841		HSISS4_RS04405	911450	912259	-	sugar phosphate phosphatase	YidA%3B catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate)%2C mannose 1-phosphate and p-nitrophenyl phosphate%3B hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form%3B member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins	gene	gene880	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04405
HSISS4_RS04410	HSISS4_00842		HSISS4_RS04410	912437	913303	+	acetyltransferase		gene	gene881	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04410
HSISS4_RS04415	HSISS4_00843		HSISS4_RS04415	913386	913772	+	hypothetical protein		gene	gene882	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04415
HSISS4_RS04420	HSISS4_00844		HSISS4_RS04420	914037	916721	+	hypothetical protein		gene	gene883	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04420
HSISS4_RS04425	HSISS4_00845		HSISS4_RS04425	916831	917577	+	NADPH-dependent oxidoreductase		gene	gene884	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04425
HSISS4_RS04430	HSISS4_00846		HSISS4_RS04430	917603	918460	-	phosphoesterase		gene	gene885	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04430
HSISS4_RS04435	HSISS4_00847		HSISS4_RS04435	918554	919672	+	epoxyqueuosine reductase		gene	gene886	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04435
HSISS4_RS04440	HSISS4_00848		HSISS4_RS04440	919843	920823	+	peptide chain release factor 2		gene	gene887	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04440
HSISS4_RS04445	HSISS4_00849		HSISS4_RS04445	920911	921603	+	cell division protein FtsE		gene	gene888	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04445
HSISS4_RS04450	HSISS4_00850		HSISS4_RS04450	921596	922525	+	cell division protein FtsX		gene	gene889	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04450
HSISS4_RS04455	HSISS4_00851		HSISS4_RS04455	922681	923163	+	Mutator mutTprotein(7%2C8-dihydro-8-oxoguanine-triphosphatase)		gene	gene890	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04455
HSISS4_RS04460	HSISS4_00852		HSISS4_RS04460	923173	924351	+	AI-2E family transporter		gene	gene891	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04460
HSISS4_RS04465	HSISS4_00853		HSISS4_RS04465	924341	925570	+	hypothetical protein		gene	gene892	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04465
HSISS4_RS04470	HSISS4_00854		HSISS4_RS04470	925692	926249	+	signal peptidase		gene	gene893	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04470
HSISS4_RS04475	HSISS4_00855		HSISS4_RS04475	926407	928533	+	cell wall hydrolase		gene	gene894	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04475
HSISS4_RS04480	HSISS4_00856		HSISS4_RS04480	928613	929836	+	peptidase T		gene	gene895	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04480
HSISS4_RS04485	HSISS4_00857		HSISS4_RS04485	929893	930393	+	hypothetical protein		gene	gene896	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04485
HSISS4_RS04490	HSISS4_00859		HSISS4_RS04490	930620	931276	+	hypothetical protein		gene	gene897	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04490
HSISS4_RS04495	HSISS4_00860		HSISS4_RS04495	931298	931978	+	cytidylate kinase		gene	gene898	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04495
HSISS4_RS04500	HSISS4_00861		HSISS4_RS04500	932138	932668	+	translation initiation factor IF-3		gene	gene899	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04500
HSISS4_RS04505	HSISS4_00862	rpmI	rpmI	932707	932907	+	50S ribosomal protein L35		gene	gene900	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04505
HSISS4_RS04510	HSISS4_00863		HSISS4_RS04510	932964	933323	+	50S ribosomal protein L20		gene	gene901	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04510
HSISS4_RS04515	HSISS4_00864		HSISS4_RS04515	933367	933840	+	GNAT family N-acetyltransferase		gene	gene902	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04515
HSISS4_RS04520	HSISS4_RS04520		HSISS4_RS04520	934232	934447	+	hypothetical protein		gene	gene903	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04520
HSISS4_RS04525	HSISS4_00866		HSISS4_RS04525	934519	934704	-	tautomerase	4-OT%3B member of subfamily 5%3B forms a dimer%3B the function in the Escherichia coli cell is unknown	gene	gene904	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04525
HSISS4_RS04530	HSISS4_00867		HSISS4_RS04530	935066	936472	+	naa-His dipeptidase	divalent metal ion-dependent extracellular dipeptidase%3B able to hydrolyze a broad range of dipeptides but no tri-%2C tetra-%2C or larger oligopeptides%3B differences in the amino acid specificity of the cleavage site varies between species%3B similar to succinyl-diaminopimelate desuccinylases	gene	gene905	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04530
HSISS4_RS04535	HSISS4_00868		HSISS4_RS04535	936513	937097	+	hypothetical protein		gene	gene906	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04535
HSISS4_RS04540	HSISS4_00869		HSISS4_RS04540	937471	941259	+	YSIRK signal domain/LPXTG anchor domain surface protein		gene	gene907	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04540
HSISS4_RS04545	HSISS4_00870		HSISS4_RS04545	941721	944756	+	dextran-binding lectin A		gene	gene908	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04545
HSISS4_RS04550	HSISS4_00871		HSISS4_RS04550	944916	945596	+	ribose-5-phosphate isomerase		gene	gene909	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04550
HSISS4_RS04555	HSISS4_00872		HSISS4_RS04555	945716	946927	+	phosphopentomutase	catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose	gene	gene910	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04555
HSISS4_RS04560	HSISS4_00873		HSISS4_RS04560	946929	947474	+	hypothetical protein		gene	gene911	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04560
HSISS4_RS04565	HSISS4_00874		HSISS4_RS04565	947493	948302	+	purine-nucleoside phosphorylase	catalyzes the formation of a purine and ribose phosphate from a purine nucleoside%3B in E. coli this enzyme functions in xanthosine degradation	gene	gene912	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04565
HSISS4_RS04570	HSISS4_00875		HSISS4_RS04570	948306	949553	+	voltage-gated chloride channel		gene	gene913	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04570
HSISS4_RS04575	HSISS4_00876		HSISS4_RS04575	949550	950263	+	glutamine amidotransferase	Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group	gene	gene914	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04575
HSISS4_RS04580	HSISS4_00877		HSISS4_RS04580	950567	951277	+	purine-nucleoside phosphorylase		gene	gene915	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04580
HSISS4_RS04585	HSISS4_00878		HSISS4_RS04585	951618	953078	+	LytR family transcriptional regulator		gene	gene916	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04585
HSISS4_RS04590	HSISS4_00879		HSISS4_RS04590	953079	953810	+	tyrosine protein phosphatase		gene	gene917	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04590
HSISS4_RS04595	HSISS4_00880		HSISS4_RS04595	953819	954511	+	Tyrosine-protein kinase modulator EpsC		gene	gene918	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04595
HSISS4_RS04600	HSISS4_00881		HSISS4_RS04600	954521	955261	+	Tyrosine-protein kinase EpsD		gene	gene919	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04600
HSISS4_RS04605	HSISS4_00882		HSISS4_RS04605	955318	956685	+	galactosyl transferase		gene	gene920	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04605
HSISS4_RS04610	HSISS4_00883		HSISS4_RS04610	956718	957890	+	alpha-D-GlcNAc alpha-1%2C2-L-rhamnosyl transferase		gene	gene921	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04610
HSISS4_RS04615	HSISS4_00884		HSISS4_RS04615	957893	959041	+	glycosyl transferase		gene	gene922	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04615
HSISS4_RS04620	HSISS4_00885		HSISS4_RS04620	959043	959684	+	capsular polysaccharide biosynthesis protein		gene	gene923	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04620
HSISS4_RS04625	HSISS4_00886		HSISS4_RS04625	959681	960652	+	hypothetical protein		gene	gene924	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04625
HSISS4_RS04630	HSISS4_00887		HSISS4_RS04630	960645	961715	+	glycosyl transferase family 2		gene	gene925	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04630
HSISS4_RS04635	HSISS4_00888		HSISS4_RS04635	961749	962894	+	polysaccharide polymerase		gene	gene926	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04635
HSISS4_RS04640	HSISS4_00889		HSISS4_RS04640	962908	964323	+	Eps6L		gene	gene927	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04640
HSISS4_RS04645	HSISS4_00890		HSISS4_RS04645	964334	965434	+	UDP-galactopyranose mutase		gene	gene928	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04645
HSISS4_RS04650	HSISS4_00891		HSISS4_RS04650	965431	966423	+	Receptor polysaccharide phosphotransferase wef(Stealth protein wefC)		gene	gene929	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04650
HSISS4_RS04655	HSISS4_00892		HSISS4_RS04655	966434	967486	+	galactofuranose transferase		gene	gene930	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04655
HSISS4_RS04660	HSISS4_00893		HSISS4_RS04660	967523	968500	-	hypothetical protein		gene	gene931	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04660
HSISS4_RS04665	HSISS4_00894		HSISS4_RS04665	968688	969506	+	hypothetical protein		gene	gene932	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04665
HSISS4_RS04670	HSISS4_00895		HSISS4_RS04670	969525	970127	+	phosphoglycerate mutase		gene	gene933	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04670
HSISS4_RS04675	HSISS4_00896		HSISS4_RS04675	970124	970732	+	hypothetical protein		gene	gene934	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04675
HSISS4_RS04680	HSISS4_00897		HSISS4_RS04680	970729	971325	+	hypothetical protein		gene	gene935	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04680
HSISS4_RS04685	HSISS4_00898		HSISS4_RS04685	971403	972539	+	AI-2E family transporter		gene	gene936	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04685
HSISS4_RS04690	HSISS4_00899		HSISS4_RS04690	972663	974099	+	6-phospho-beta-glucosidase		gene	gene937	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04690
HSISS4_RS04695	HSISS4_00900		HSISS4_RS04695	974346	974624	+	hypothetical protein		gene	gene938	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04695
HSISS4_RS04700	HSISS4_00901		HSISS4_RS04700	974642	976219	+	Ubiquinone biosynthesis monooxygenase UbiB		gene	gene939	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04700
HSISS4_RS04705	HSISS4_00902		HSISS4_RS04705	976223	976843	+	lipase/acylhydrolase		gene	gene940	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04705
HSISS4_RS04710	HSISS4_00903		HSISS4_RS04710	976840	977691	+	patatin family protein		gene	gene941	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04710
HSISS4_RS04715	HSISS4_00904		HSISS4_RS04715	977716	979062	-	D-alanyl-D-alanine carboxypeptidase		gene	gene942	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04715
HSISS4_RS04720	HSISS4_00905		HSISS4_RS04720	979294	980490	-	hypothetical protein		gene	gene943	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04720
HSISS4_RS04725	HSISS4_00906		HSISS4_RS04725	980704	981357	+	uracil-DNA glycosylase		gene	gene944	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04725
HSISS4_RS04730	HSISS4_00907		HSISS4_RS04730	981377	982645	+	dihydroorotase		gene	gene945	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04730
HSISS4_RS04735	HSISS4_00908		HSISS4_RS04735	982723	984690	+	hypothetical protein		gene	gene946	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04735
HSISS4_RS04740	HSISS4_00909		HSISS4_RS04740	984858	986147	-	histidine kinase		gene	gene947	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04740
HSISS4_RS04745	HSISS4_00910		HSISS4_RS04745	986137	987393	-	hypothetical protein		gene	gene948	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04745
HSISS4_RS04750	HSISS4_00911		HSISS4_RS04750	987580	988551	+	acetoin dehydrogenase E1 component alpha-subunit		gene	gene949	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04750
HSISS4_RS04755	HSISS4_00912		HSISS4_RS04755	988576	989574	+	acetoin dehydrogenase E1 component beta-subuni		gene	gene950	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04755
HSISS4_RS04760	HSISS4_00913		HSISS4_RS04760	989809	991197	+	dihydrolipoamide acetyltransferase		gene	gene951	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04760
HSISS4_RS04765	HSISS4_00914		HSISS4_RS04765	991340	993094	+	dihydrolipoamide dehydrogenase		gene	gene952	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04765
HSISS4_RS04770	HSISS4_00915		HSISS4_RS04770	993368	996919	+	N-acetylmuramoyl-L-alanine amidase		gene	gene953	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04770
HSISS4_RS04775	HSISS4_00916		HSISS4_RS04775	997214	1000144	+	N-acetylmuramoyl-L-alanine amidase		gene	gene954	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04775
HSISS4_RS04780	HSISS4_00917		HSISS4_RS04780	1000264	1003977	+	pullulanase		gene	gene955	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04780
HSISS4_RS04785	HSISS4_00918		HSISS4_RS04785	1004228	1005100	+	iron ABC transporter substrate-binding protein		gene	gene956	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04785
HSISS4_RS04790	HSISS4_00919		HSISS4_RS04790	1005106	1006311	+	Ferrous iron transport peroxidase EfeB		gene	gene957	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04790
HSISS4_RS04795	HSISS4_00920		HSISS4_RS04795	1006289	1007974	+	FTR1 family iron permease		gene	gene958	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04795
HSISS4_RS04800	HSISS4_00921		HSISS4_RS04800	1007961	1008689	+	preprotein translocase subunit TatC		gene	gene959	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04800
HSISS4_RS04805	HSISS4_00922		HSISS4_RS04805	1008702	1008887	+	protein translocase TatA		gene	gene960	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04805
HSISS4_RS04810	HSISS4_00923		HSISS4_RS04810	1009287	1010423	-	sugar ABC transporter ATP-binding protein		gene	gene961	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04810
HSISS4_RS04815	HSISS4_00924		HSISS4_RS04815	1010439	1011275	-	Maltose/maltodextrin ABC transporter permeaseprotein MalG		gene	gene962	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04815
HSISS4_RS04820	HSISS4_00925		HSISS4_RS04820	1011275	1012633	-	Maltose/maltodextrin ABC transporter permeaseprotein MalF		gene	gene963	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04820
HSISS4_RS04825	HSISS4_00926		HSISS4_RS04825	1012723	1013970	-	maltose/maltodextrin-binding protein		gene	gene964	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04825
HSISS4_RS04830	HSISS4_00927		HSISS4_RS04830	1014151	1015155	+	LacI family transcriptional regulator		gene	gene965	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04830
HSISS4_RS04835	HSISS4_00928		HSISS4_RS04835	1015409	1016908	+	4-alpha-glucanotransferase		gene	gene966	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04835
HSISS4_RS04840	HSISS4_00929		HSISS4_RS04840	1016910	1019171	+	maltose phosphorylase		gene	gene967	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04840
HSISS4_RS04845	HSISS4_RS04845		HSISS4_RS04845	1019282	1019503	-	hypothetical protein		gene	gene968	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04845
HSISS4_RS04850	HSISS4_RS04850		HSISS4_RS04850	1019669	1020325	-	hypothetical protein	incomplete%3B partial in the middle of a contig%3B missing stop	gene	gene969	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04850
HSISS4_RS04855	HSISS4_00931		HSISS4_RS04855	1020533	1021522	+	lipoate--protein ligase A		gene	gene970	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04855
HSISS4_RS04860	HSISS4_00932	xerS	xerS	1021808	1022878	+	tyrosine recombinase XerS	site-specific tyrosine recombinase which cuts and rejoins DNA molecules%3B binds cooperatively to specific DNA consensus sites%3B essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation%3B cell division protein FtsK may regulate the XerS	gene	gene971	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04860
HSISS4_RS04865	HSISS4_00933		HSISS4_RS04865	1023041	1025581	-	aminopeptidase N		gene	gene972	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04865
HSISS4_RS04870	HSISS4_00934		HSISS4_RS04870	1025715	1026368	-	PhoU family transcriptional regulator		gene	gene973	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04870
HSISS4_RS04875	HSISS4_00935		HSISS4_RS04875	1026397	1027155	-	phosphate ABC transporter ATP-binding protein		gene	gene974	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04875
HSISS4_RS04880	HSISS4_00936		HSISS4_RS04880	1027168	1027971	-	phosphate ABC transporter ATP-binding protein	ATP-binding protein%3B PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation	gene	gene975	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04880
HSISS4_RS04885	HSISS4_00937		HSISS4_RS04885	1027982	1028866	-	phosphate ABC transporter permease		gene	gene976	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04885
HSISS4_RS04890	HSISS4_00938		HSISS4_RS04890	1028856	1029770	-	phosphate ABC transporter permease		gene	gene977	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04890
HSISS4_RS04895	HSISS4_00939		HSISS4_RS04895	1029773	1030648	-	phosphate-binding protein		gene	gene978	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04895
HSISS4_RS04900	HSISS4_00940		HSISS4_RS04900	1030774	1032084	-	RNA methyltransferase		gene	gene979	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04900
HSISS4_RS04905	HSISS4_00941		HSISS4_RS04905	1032165	1032932	-	inositol-1-monophosphatase		gene	gene980	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04905
HSISS4_RS04910	HSISS4_00942		HSISS4_RS04910	1032922	1033203	-	hypothetical protein		gene	gene981	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04910
HSISS4_RS04915	HSISS4_00943		HSISS4_RS04915	1033196	1033609	-	ArsR family transcriptional regulator		gene	gene982	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04915
HSISS4_RS04920	HSISS4_00944		HSISS4_RS04920	1033679	1034590	-	bifunctional riboflavin kinase/FMN adenylyltransferase		gene	gene983	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04920
HSISS4_RS04925	HSISS4_00945	truB	truB	1034587	1035468	-	tRNA pseudouridine synthase B	catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs	gene	gene984	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04925
HSISS4_RS04930	HSISS4_00946		HSISS4_RS04930	1035588	1036934	-	hypothetical protein		gene	gene985	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04930
HSISS4_RS04935	HSISS4_00947		HSISS4_RS04935	1036936	1037169	-	hypothetical protein		gene	gene986	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04935
HSISS4_RS04940	HSISS4_00948		HSISS4_RS04940	1037258	1037878	-	type I restriction endonuclease subunit S		gene	gene987	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04940
HSISS4_RS04945	HSISS4_00949		HSISS4_RS04945	1038005	1038499	-	2-Cys peroxiredoxin		gene	gene988	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04945
HSISS4_RS04950	HSISS4_00950		HSISS4_RS04950	1038563	1039318	-	hypothetical protein		gene	gene989	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04950
HSISS4_RS04955	HSISS4_00951		HSISS4_RS04955	1039379	1040659	-	O-acetylhomoserine (thiol)-lyase	catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol	gene	gene990	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04955
HSISS4_RS04960	HSISS4_00952		HSISS4_RS04960	1040780	1043089	-	ATP-dependent DNA helicase UvrD/PcrA		gene	gene991	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04960
HSISS4_RS04965	HSISS4_00953		HSISS4_RS04965	1043597	1044940	+	Sodium/glycine symporter GlyP		gene	gene992	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04965
HSISS4_RS04970	HSISS4_00954		HSISS4_RS04970	1045068	1046438	+	tRNA modification GTPase		gene	gene993	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04970
HSISS4_RS04975	HSISS4_00955		HSISS4_RS04975	1046615	1047523	+	AraC family transcriptional regulator		gene	gene994	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04975
HSISS4_RS04980	HSISS4_00956		HSISS4_RS04980	1047559	1049805	-	bifunctional metallophosphatase/5'-nucleotidase		gene	gene995	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04980
HSISS4_RS04985	HSISS4_00957		HSISS4_RS04985	1049915	1050568	-	amino acid ABC transporter permease		gene	gene996	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04985
HSISS4_RS04990	HSISS4_00958		HSISS4_RS04990	1050627	1051475	-	ABC transporter substrate-binding protein		gene	gene997	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04990
HSISS4_RS04995	HSISS4_00959		HSISS4_RS04995	1051580	1053031	-	amidase	catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia	gene	gene998	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS04995
HSISS4_RS05000	HSISS4_00960		HSISS4_RS05000	1053115	1053744	-	orotate phosphoribosyltransferase		gene	gene999	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05000
HSISS4_RS05005	HSISS4_00961		HSISS4_RS05005	1053832	1054527	-	orotidine 5'-phosphate decarboxylase		gene	gene1000	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05005
HSISS4_RS05010	HSISS4_00962		HSISS4_RS05010	1054728	1055858	-	type III-A CRISPR-associated protein Csm6		gene	gene1001	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05010
HSISS4_RS05015	HSISS4_00963		HSISS4_RS05015	1056029	1057189	-	type III-A CRISPR-associated protein Csm6		gene	gene1002	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05015
HSISS4_RS05020	HSISS4_00964		HSISS4_RS05020	1057186	1058259	-	type III-A CRISPR-associated RAMP protein Csm5		gene	gene1003	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05020
HSISS4_RS05025	HSISS4_00965		HSISS4_RS05025	1058262	1059161	-	type III-A CRISPR-associated RAMP protein Csm4		gene	gene1004	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05025
HSISS4_RS05030	HSISS4_00966		HSISS4_RS05030	1059163	1059825	-	type III-A CRISPR-associated RAMP protein Csm3		gene	gene1005	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05030
HSISS4_RS05035	HSISS4_00967		HSISS4_RS05035	1059825	1060205	-	type III-A CRISPR-associated protein Csm2		gene	gene1006	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05035
HSISS4_RS05040	HSISS4_00968		HSISS4_RS05040	1060209	1062479	-	type III-A CRISPR-associated protein Cas10/Csm1		gene	gene1007	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05040
HSISS4_RS05045	HSISS4_00969		HSISS4_RS05045	1062460	1063191	-	CRISPR-associated endoribonuclease Cas6		gene	gene1008	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05045
HSISS4_RS05050	HSISS4_00970		HSISS4_RS05050	1063748	1063960	+	hypothetical protein		gene	gene1009	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05050
HSISS4_RS05055	HSISS4_00971		HSISS4_RS05055	1064406	1064735	-	CRISPR-associated endonuclease Cas2		gene	gene1010	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05055
HSISS4_RS05060	HSISS4_RS05060		HSISS4_RS05060	1064735	1065739	-	CRISPR-associated protein Cas1	frameshifted	gene	gene1011	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05060
HSISS4_RS05065	HSISS4_00974		HSISS4_RS05065	1065879	1066835	-	dihydroorotate dehydrogenase B catalytic subunit	catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%2C using a flavin nucleotide as an essential cofactor%3B subclass 1B is a heterotetramer consisting of two PyrDB subunits%2C similar to the PyrDA subunits and two PyrK subunits	gene	gene1012	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05065
HSISS4_RS05070	HSISS4_00975		HSISS4_RS05070	1066845	1067618	-	dihydroorotate dehydrogenase electron transfer subunit	responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+)	gene	gene1013	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05070
HSISS4_RS05075	HSISS4_00976		HSISS4_RS05075	1067959	1068507	-	4-methyl-5(B-hydroxyethyl)-thiazole-monophosphate biosynthesis enzyme		gene	gene1014	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05075
HSISS4_RS05080	HSISS4_00977		HSISS4_RS05080	1068641	1069441	-	hypothetical protein		gene	gene1015	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05080
HSISS4_RS05085	HSISS4_00978		HSISS4_RS05085	1069960	1071618	+	hypothetical protein		gene	gene1016	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05085
HSISS4_RS05090	HSISS4_00979		HSISS4_RS05090	1071793	1073337	+	hypothetical protein		gene	gene1017	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05090
HSISS4_RS05095	HSISS4_00980		HSISS4_RS05095	1073607	1074434	+	multidrug ABC transporter ATPase		gene	gene1018	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05095
HSISS4_RS05100	HSISS4_00981		HSISS4_RS05100	1074427	1075125	+	hypothetical protein		gene	gene1019	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05100
HSISS4_RS05105	HSISS4_00982		HSISS4_RS05105	1075207	1076547	+	MATE family efflux transporter		gene	gene1020	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05105
HSISS4_RS05110	HSISS4_00983		HSISS4_RS05110	1076592	1077560	-	hypothetical protein		gene	gene1021	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05110
HSISS4_RS05115	HSISS4_00984		HSISS4_RS05115	1077775	1080489	+	hypothetical protein		gene	gene1022	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05115
HSISS4_RS05120	HSISS4_00985		HSISS4_RS05120	1080562	1081197	+	phosphoglycolate phosphatase		gene	gene1023	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05120
HSISS4_RS05125	HSISS4_00986		HSISS4_RS05125	1081259	1082023	-	uridine phosphorylase		gene	gene1024	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05125
HSISS4_RS05130	HSISS4_00987		HSISS4_RS05130	1082146	1083921	-	pyruvate oxidase		gene	gene1025	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05130
HSISS4_RS05135	HSISS4_00989		HSISS4_RS05135	1084283	1086505	-	Lead%2C cadmium%2C zinc and mercury transporting ATPase Copper-translocating P-type ATPase		gene	gene1026	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05135
HSISS4_RS05140	HSISS4_00990		HSISS4_RS05140	1086516	1086887	-	ATPase		gene	gene1027	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05140
HSISS4_RS05145	HSISS4_00991		HSISS4_RS05145	1086906	1087301	-	uracil phosphoribosyltransferase		gene	gene1028	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05145
HSISS4_RS05150	HSISS4_00993		HSISS4_RS05150	1087765	1088802	-	alcohol dehydrogenase		gene	gene1029	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05150
HSISS4_RS05155	HSISS4_00994		HSISS4_RS05155	1088899	1089993	-	Ferrochelatase protoheme ferro-lyase		gene	gene1030	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05155
HSISS4_RS05160	HSISS4_00995		HSISS4_RS05160	1090105	1091016	-	hypothetical protein		gene	gene1031	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05160
HSISS4_RS05165	HSISS4_00996		HSISS4_RS05165	1091150	1091689	+	TetR family transcriptional regulator		gene	gene1032	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05165
HSISS4_RS05170	HSISS4_00997		HSISS4_RS05170	1091705	1092205	+	hypothetical protein		gene	gene1033	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05170
HSISS4_RS05175	HSISS4_00998		HSISS4_RS05175	1092426	1093049	-	transcriptional regulator		gene	gene1034	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05175
HSISS4_RS05180	HSISS4_00999		HSISS4_RS05180	1093089	1094171	-	antibiotic ABC transporter permease		gene	gene1035	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05180
HSISS4_RS05185	HSISS4_01000		HSISS4_RS05185	1094173	1094889	-	methionine ABC transporter ATP-binding protein		gene	gene1036	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05185
HSISS4_RS05190	HSISS4_01001		HSISS4_RS05190	1095136	1095993	-	short-chain dehydrogenase/reductase		gene	gene1037	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05190
HSISS4_RS05195	HSISS4_01002		HSISS4_RS05195	1095995	1096831	-	hydrolase		gene	gene1038	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05195
HSISS4_RS05200	HSISS4_01003		HSISS4_RS05200	1096845	1097849	-	quinone oxidoreductase		gene	gene1039	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05200
HSISS4_RS05205	HSISS4_01004		HSISS4_RS05205	1097928	1098359	-	Rrf2 family transcriptional regulator		gene	gene1040	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05205
HSISS4_RS05210	HSISS4_01005		HSISS4_RS05210	1098499	1098861	-	nicotinamide mononucleotide transporter PnuC	incomplete%3B partial in the middle of a contig%3B missing start	gene	gene1041	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05210
HSISS4_RS05215	HSISS4_01006		HSISS4_RS05215	1099028	1099828	-	energy-coupling factor ABC transporter ATP-binding protein		gene	gene1042	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05215
HSISS4_RS05220	HSISS4_01007		HSISS4_RS05220	1099815	1100651	-	ATPase component of energizing module of queuosine-regulated ECF transporter		gene	gene1043	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05220
HSISS4_RS05225	HSISS4_01008		HSISS4_RS05225	1100627	1101421	-	ABC transporter permease		gene	gene1044	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05225
HSISS4_RS05230	HSISS4_01009		HSISS4_RS05230	1101418	1102020	-	Substrate-specific component of queuosine-regulated ECF transporter		gene	gene1045	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05230
HSISS4_RS05235	HSISS4_RS05235		HSISS4_RS05235	1102337	1103138	-	phenazine biosynthesis protein	frameshifted	gene	gene1046	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05235
HSISS4_RS05240	HSISS4_01012		HSISS4_RS05240	1103238	1103783	-	TetR family transcriptional regulator		gene	gene1047	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05240
HSISS4_RS05245	HSISS4_01013		HSISS4_RS05245	1104013	1104714	+	ABC transporter ATP-binding protein		gene	gene1048	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05245
HSISS4_RS05250	HSISS4_01014		HSISS4_RS05250	1104727	1107390	+	ABC transporter permease		gene	gene1049	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05250
HSISS4_RS05255	HSISS4_RS05255		HSISS4_RS05255	1107404	1107601	-	hypothetical protein		gene	gene1050	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05255
HSISS4_RS05260	HSISS4_01015		HSISS4_RS05260	1107667	1107852	+	transposase	internal stop	gene	gene1051	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05260
HSISS4_RS05265	HSISS4_01016		HSISS4_RS05265	1107929	1108552	-	hypothetical protein		gene	gene1052	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05265
HSISS4_RS05270	HSISS4_01017		HSISS4_RS05270	1108549	1110069	-	amino acid ABC transporter substrate-binding protein		gene	gene1053	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05270
HSISS4_RS05275	HSISS4_01018		HSISS4_RS05275	1110062	1110790	-	glycine/betaine ABC transporter permease		gene	gene1054	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05275
HSISS4_RS05280	HSISS4_01019		HSISS4_RS05280	1110783	1111637	-	NAD(P)-dependent oxidoreductase		gene	gene1055	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05280
HSISS4_RS05285	HSISS4_01020		HSISS4_RS05285	1111656	1112105	-	transcriptional regulator		gene	gene1056	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05285
HSISS4_RS05290	HSISS4_01021		HSISS4_RS05290	1112192	1112956	-	appr-1-p processing enzyme family domain-containing protein		gene	gene1057	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05290
HSISS4_RS05295	HSISS4_01022		HSISS4_RS05295	1112941	1113774	-	NAD-dependent protein deacetylase		gene	gene1058	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05295
HSISS4_RS05300	HSISS4_01023		HSISS4_RS05300	1113779	1114210	-	hypothetical protein		gene	gene1059	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05300
HSISS4_RS05305	HSISS4_01024		HSISS4_RS05305	1114391	1115110	-	alpha-acetolactate decarboxylase		gene	gene1060	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05305
HSISS4_RS05310	HSISS4_01025		HSISS4_RS05310	1115126	1116802	-	acetolactate synthase	catalyzes the formation of 2-acetolactate from pyruvate in stationary phase	gene	gene1061	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05310
HSISS4_RS05315	HSISS4_01026		HSISS4_RS05315	1117016	1117357	-	hypothetical protein		gene	gene1062	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05315
HSISS4_RS05320	HSISS4_01027		HSISS4_RS05320	1117455	1118834	-	hypothetical protein		gene	gene1063	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05320
HSISS4_RS05325	HSISS4_01028		HSISS4_RS05325	1118882	1120714	-	elongation factor 4		gene	gene1064	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05325
HSISS4_RS05330	HSISS4_01030		HSISS4_RS05330	1121102	1121866	-	acetoin reductase		gene	gene1065	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05330
HSISS4_RS05335	HSISS4_01031		HSISS4_RS05335	1122079	1122372	-	rhodanese-like domain-containing protein		gene	gene1066	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05335
HSISS4_RS05340	HSISS4_01032		HSISS4_RS05340	1122374	1122802	-	nucleoside-diphosphate kinase		gene	gene1067	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05340
HSISS4_RS05345	HSISS4_01033		HSISS4_RS05345	1122955	1124100	+	5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase		gene	gene1068	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05345
HSISS4_RS05350	HSISS4_01034		HSISS4_RS05350	1124160	1125503	-	tRNA (uracil-5-)-methyltransferase Gid		gene	gene1069	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05350
HSISS4_RS05355	HSISS4_01035		HSISS4_RS05355	1125604	1126898	-	histidine kinase	frameshifted	gene	gene1070	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05355
HSISS4_RS05360	HSISS4_01036		HSISS4_RS05360	1126988	1127647	-	DNA-binding response regulator		gene	gene1071	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05360
HSISS4_RS05365	HSISS4_01037		HSISS4_RS05365	1127728	1128378	-	membrane protein		gene	gene1072	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05365
HSISS4_RS05370	HSISS4_01038		HSISS4_RS05370	1128365	1129108	-	lantibiotic ABC transporter permease		gene	gene1073	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05370
HSISS4_RS05375	HSISS4_01039		HSISS4_RS05375	1129098	1129772	-	hypothetical protein		gene	gene1074	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05375
HSISS4_RS05380	HSISS4_01040		HSISS4_RS05380	1129956	1132100	-	DNA topoisomerase I		gene	gene1075	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05380
HSISS4_RS05385	HSISS4_01041		HSISS4_RS05385	1132268	1133107	-	DNA processing protein DprA		gene	gene1076	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05385
HSISS4_RS05390	HSISS4_01042		HSISS4_RS05390	1133174	1134094	-	transcriptional regulator		gene	gene1077	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05390
HSISS4_RS05395	HSISS4_01043		HSISS4_RS05395	1134101	1134871	-	ribonuclease HII		gene	gene1078	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05395
HSISS4_RS05400	HSISS4_01044	rbgA	rbgA	1134858	1135712	-	50S ribosomal subunit maturation GTPase RbgA (YlqF)	essential GTPase%3B functions in ribosome assembly%3B binds a unique part of the 23S rRNA%3B interacts with ribosomal protein L25(Ctc)	gene	gene1079	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05400
HSISS4_RS05405	HSISS4_01045		HSISS4_RS05405	1135841	1136530	-	pleiotropic regulator of exopolysaccharide synthesis%2C competence and biofilm formation Ftr%2C nREfamily		gene	gene1080	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05405
HSISS4_RS05410	HSISS4_01046		HSISS4_RS05410	1136625	1137140	-	transcriptional regulator		gene	gene1081	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05410
HSISS4_RS05415	HSISS4_01047		HSISS4_RS05415	1137163	1137690	-	membrane protein		gene	gene1082	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05415
HSISS4_RS05420	HSISS4_01048		HSISS4_RS05420	1137803	1139365	-	signal recognition particle protein		gene	gene1083	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05420
HSISS4_RS05425	HSISS4_01049		HSISS4_RS05425	1139398	1139730	-	DNA-binding protein		gene	gene1084	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05425
HSISS4_RS05430	HSISS4_01050		HSISS4_RS05430	1139796	1140494	-	GntR family transcriptional regulator		gene	gene1085	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05430
HSISS4_RS05435	HSISS4_01051		HSISS4_RS05435	1140659	1142221	+	GMP synthetase		gene	gene1086	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05435
HSISS4_RS05440	HSISS4_01052		HSISS4_RS05440	1142508	1143092	-	ribosomal-protein-L7p-serine acetyltransferase		gene	gene1087	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05440
HSISS4_RS05445	HSISS4_01053	adhP	adhP	1143377	1144396	-	zinc-dependent alcohol dehydrogenase	similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs	gene	gene1088	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05445
HSISS4_RS05450	HSISS4_01054		HSISS4_RS05450	1144558	1144839	-	hypothetical protein		gene	gene1089	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05450
HSISS4_RS05455	HSISS4_RS05455		HSISS4_RS05455	1144817	1145194	-	hypothetical protein		gene	gene1090	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05455
HSISS4_RS05460	HSISS4_01055		HSISS4_RS05460	1145191	1146606	-	ImpB/MucB/SamB family protein		gene	gene1091	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05460
HSISS4_RS05465	HSISS4_01056		HSISS4_RS05465	1146720	1147571	-	amino acid ABC transporter aminoacid-binding protein		gene	gene1092	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05465
HSISS4_RS05470	HSISS4_01057		HSISS4_RS05470	1147584	1148213	-	amino acid ABC transporter ATP-binding protein		gene	gene1093	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05470
HSISS4_RS05475	HSISS4_01058		HSISS4_RS05475	1148222	1148863	-	amino acid ABC transporter permease		gene	gene1094	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05475
HSISS4_RS05480	HSISS4_01059		HSISS4_RS05480	1149064	1149396	-	hypothetical protein		gene	gene1095	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05480
HSISS4_RS05485	HSISS4_01060		HSISS4_RS05485	1149514	1151322	-	glutamine--fructose-6-phosphate aminotransferase		gene	gene1096	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05485
HSISS4_RS05490	HSISS4_01061		HSISS4_RS05490	1151530	1152438	+	LysR family transcriptional regulator		gene	gene1097	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05490
HSISS4_RS05495	HSISS4_01062		HSISS4_RS05495	1152532	1153245	-	peptidoglycan hydrolase		gene	gene1098	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05495
HSISS4_RS05500	HSISS4_01063		HSISS4_RS05500	1153418	1154425	+	hypothetical protein		gene	gene1099	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05500
HSISS4_RS05505	HSISS4_01064		HSISS4_RS05505	1154480	1154791	-	hypothetical protein		gene	gene1100	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05505
HSISS4_RS05510	HSISS4_01065		HSISS4_RS05510	1154937	1155335	-	hypothetical protein		gene	gene1101	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05510
HSISS4_RS05515	HSISS4_01066		HSISS4_RS05515	1155554	1157098	-	zinc-binding protein		gene	gene1102	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05515
HSISS4_RS05520	HSISS4_01067		HSISS4_RS05520	1157256	1158077	+	hypothetical protein		gene	gene1103	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05520
HSISS4_RS05525	HSISS4_01068		HSISS4_RS05525	1158133	1159530	-	hypothetical protein		gene	gene1104	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05525
HSISS4_RS05530	HSISS4_01069		HSISS4_RS05530	1159548	1160459	-	sporulation protein		gene	gene1105	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05530
HSISS4_RS05535	HSISS4_01070		HSISS4_RS05535	1160456	1161430	-	hypothetical protein		gene	gene1106	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05535
HSISS4_RS05540	HSISS4_01071		HSISS4_RS05540	1161427	1162317	-	RNase adaptor protein RapZ		gene	gene1107	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05540
HSISS4_RS05545	HSISS4_01072		HSISS4_RS05545	1162298	1163068	-	hypothetical protein		gene	gene1108	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05545
HSISS4_RS05550	HSISS4_01073		HSISS4_RS05550	1163195	1165105	-	serine protease		gene	gene1109	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05550
HSISS4_RS05555	HSISS4_01074		HSISS4_RS05555	1165367	1165858	-	7-cyano-7-deazaguanine reductase		gene	gene1110	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05555
HSISS4_RS05560	HSISS4_01075		HSISS4_RS05560	1165981	1166697	-	7-carboxy-7-deazaguanine synthase		gene	gene1111	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05560
HSISS4_RS05565	HSISS4_01076		HSISS4_RS05565	1166690	1167133	-	Queuosine biosynthesis QueD%2C PTPS-I		gene	gene1112	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05565
HSISS4_RS05570	HSISS4_01077		HSISS4_RS05570	1167133	1167786	-	7-cyano-7-deazaguanine synthase		gene	gene1113	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05570
HSISS4_RS05575	HSISS4_01078		HSISS4_RS05575	1167960	1168340	-	hypothetical protein		gene	gene1114	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05575
HSISS4_RS05580	HSISS4_01079		HSISS4_RS05580	1168693	1169892	-	hypothetical protein		gene	gene1115	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05580
HSISS4_RS05585	HSISS4_01080		HSISS4_RS05585	1170002	1170409	-	hypothetical protein		gene	gene1116	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05585
HSISS4_RS05590	HSISS4_01081	asnC	asnC	1170436	1171782	-	asparagine--tRNA ligase	catalyzes a two-step reaction%2C first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA	gene	gene1117	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05590
HSISS4_RS05595	HSISS4_01082		HSISS4_RS05595	1171819	1173000	-	aspartate aminotransferase		gene	gene1118	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05595
HSISS4_RS05600	HSISS4_01083		HSISS4_RS05600	1173005	1173487	-	hypothetical protein		gene	gene1119	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05600
HSISS4_RS05605	HSISS4_01084		HSISS4_RS05605	1173645	1176131	-	ATP-dependent DNA helicase	unwinds DNA	gene	gene1120	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05605
HSISS4_RS05610	HSISS4_01085		HSISS4_RS05610	1176227	1176862	+	hypothetical protein		gene	gene1121	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05610
HSISS4_RS05615	HSISS4_01086		HSISS4_RS05615	1176968	1177924	-	deoxyribose ABC transporter permease		gene	gene1122	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05615
HSISS4_RS05620	HSISS4_01087		HSISS4_RS05620	1177926	1178993	-	deoxyribose ABC transporter permease		gene	gene1123	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05620
HSISS4_RS05625	HSISS4_01088		HSISS4_RS05625	1178986	1180524	-	heme ABC transporter ATP-binding protein		gene	gene1124	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05625
HSISS4_RS05630	HSISS4_01089		HSISS4_RS05630	1180623	1181693	-	membrane protein		gene	gene1125	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05630
HSISS4_RS05635	HSISS4_01090		HSISS4_RS05635	1181755	1182153	-	cytidine deaminase	Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis	gene	gene1126	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05635
HSISS4_RS05640	HSISS4_01091		HSISS4_RS05640	1182140	1182802	-	2-deoxyribose-5-phosphate aldolase	catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate	gene	gene1127	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05640
HSISS4_RS05645	HSISS4_01092	deoA	deoA	1182836	1184113	-	thymidine phosphorylase	Catalyzes the reversible phosphorolysis of thymidine%2C deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate	gene	gene1128	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05645
HSISS4_RS05650	HSISS4_01093		HSISS4_RS05650	1184110	1184700	-	16S rRNA methyltransferase		gene	gene1129	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05650
HSISS4_RS05655	HSISS4_01094		HSISS4_RS05655	1184813	1185733	+	pantothenate kinase		gene	gene1130	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05655
HSISS4_RS05660	HSISS4_01095		HSISS4_RS05660	1185803	1186039	+	30S ribosomal protein S20		gene	gene1131	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05660
HSISS4_RS05665	HSISS4_01096		HSISS4_RS05665	1186117	1187532	-	two-component sensor histidine kinase		gene	gene1132	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05665
HSISS4_RS05670	HSISS4_01097		HSISS4_RS05670	1187522	1188196	-	DNA-binding response regulator		gene	gene1133	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05670
HSISS4_RS05675	HSISS4_01098		HSISS4_RS05675	1188394	1190064	-	formate--tetrahydrofolate ligase		gene	gene1134	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05675
HSISS4_RS05680	HSISS4_01099		HSISS4_RS05680	1190258	1190941	+	phosphopantothenate--cysteine ligase		gene	gene1135	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05680
HSISS4_RS05685	HSISS4_01100		HSISS4_RS05685	1190934	1191479	+	phosphopantothenoylcysteine decarboxylase	decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.	gene	gene1136	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05685
HSISS4_RS05690	HSISS4_01101		HSISS4_RS05690	1191508	1192080	+	substrate-specific component PanT of pantothenate ECF transporter		gene	gene1137	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05690
HSISS4_RS05695	HSISS4_01102		HSISS4_RS05695	1192162	1193880	+	phosphoglucomutase	catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate	gene	gene1138	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05695
HSISS4_RS05700	HSISS4_01103		HSISS4_RS05700	1194019	1194894	-	5%2C10-methylenetetrahydrofolate reductase		gene	gene1139	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05700
HSISS4_RS05705	HSISS4_01104		HSISS4_RS05705	1195081	1197330	-	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase		gene	gene1140	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05705
HSISS4_RS05710	HSISS4_01105		HSISS4_RS05710	1197583	1197933	-	hypothetical protein		gene	gene1141	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05710
HSISS4_RS05715	HSISS4_01106		HSISS4_RS05715	1198080	1199810	+	para-aminobenzoate synthase aminase subunit		gene	gene1142	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05715
HSISS4_RS05720	HSISS4_01107		HSISS4_RS05720	1200026	1202662	+	Lead%2C cadmium%2C zinc and mercury transporting ATPase Copper-translocating P-type ATPase		gene	gene1143	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05720
HSISS4_RS05725	HSISS4_01108		HSISS4_RS05725	1202811	1204079	-	D-alanyl-lipoteichoic acid biosynthesis protein DltD		gene	gene1144	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05725
HSISS4_RS05730	HSISS4_01109		HSISS4_RS05730	1204072	1204311	-	D-alanine--poly(phosphoribitol) ligase subunit 2		gene	gene1145	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05730
HSISS4_RS05735	HSISS4_01110		HSISS4_RS05735	1204329	1205576	-	D-alanyl-lipoteichoic acid biosynthesis protein DltB		gene	gene1146	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05735
HSISS4_RS05740	HSISS4_01111		HSISS4_RS05740	1205573	1207123	-	D-alanine--poly(phosphoribitol) ligase	transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid	gene	gene1147	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05740
HSISS4_RS05745	HSISS4_01112		HSISS4_RS05745	1207132	1207263	-	D-alanyl-lipoteichoic acid biosynthesis protein DltX		gene	gene1148	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05745
HSISS4_RS05750	HSISS4_01113		HSISS4_RS05750	1207525	1208490	-	integrase		gene	gene1149	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05750
HSISS4_RS05755	HSISS4_01114		HSISS4_RS05755	1208487	1209164	-	transposase		gene	gene1150	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05755
HSISS4_RS05760	HSISS4_01115		HSISS4_RS05760	1209348	1209821	-	transposase		gene	gene1151	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05760
HSISS4_RS05765	HSISS4_01116		HSISS4_RS05765	1209985	1211733	-	ABC transporter ATP-binding/permease		gene	gene1152	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05765
HSISS4_RS05770	HSISS4_01117		HSISS4_RS05770	1211723	1213462	-	Lipid A export ATP-binding/permease MsbA		gene	gene1153	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05770
HSISS4_RS05775	HSISS4_01118		HSISS4_RS05775	1213493	1214104	-	lytic transglycosylase		gene	gene1154	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05775
HSISS4_RS05780	HSISS4_01119		HSISS4_RS05780	1214106	1215083	-	hypothetical protein		gene	gene1155	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05780
HSISS4_RS05785	HSISS4_01120	glyA	glyA	1215089	1216339	-	serine hydroxymethyltransferase	catalyzes the reaction of glycine with 5%2C10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate	gene	gene1156	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05785
HSISS4_RS05790	HSISS4_01121		HSISS4_RS05790	1216432	1217037	-	threonylcarbamoyl-AMP synthase		gene	gene1157	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05790
HSISS4_RS05795	HSISS4_01122		HSISS4_RS05795	1217024	1217857	-	protein-(glutamine-N5) methyltransferase%2C release factor-specific		gene	gene1158	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05795
HSISS4_RS05800	HSISS4_01123		HSISS4_RS05800	1217854	1218933	-	peptide chain release factor 1		gene	gene1159	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05800
HSISS4_RS05805	HSISS4_01124		HSISS4_RS05805	1218971	1219567	-	thymidine kinase	catalyzes the formation of thymidine 5'-phosphate from thymidine	gene	gene1160	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05805
HSISS4_RS05810	HSISS4_01125		HSISS4_RS05810	1219752	1220762	-	adenosine deaminase		gene	gene1161	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05810
HSISS4_RS05815	HSISS4_01126		HSISS4_RS05815	1220935	1221723	+	thiol:disulfide oxidoreductase		gene	gene1162	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05815
HSISS4_RS05820	HSISS4_01127		HSISS4_RS05820	1221804	1222748	+	oligoribonuclease		gene	gene1163	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05820
HSISS4_RS05825	HSISS4_01128		HSISS4_RS05825	1222735	1223667	+	thiamin biosynthesis lipoprotein ApbE		gene	gene1164	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05825
HSISS4_RS05830	HSISS4_01129		HSISS4_RS05830	1223774	1224016	+	50S ribosomal protein L31		gene	gene1165	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05830
HSISS4_RS05835	HSISS4_01130		HSISS4_RS05835	1224143	1225405	-	hypothetical protein		gene	gene1166	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05835
HSISS4_RS05840	HSISS4_01131		HSISS4_RS05840	1225546	1226514	-	hypothetical protein		gene	gene1167	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05840
HSISS4_RS05845	HSISS4_01132		HSISS4_RS05845	1226629	1227030	-	hypothetical protein		gene	gene1168	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05845
HSISS4_RS05850	HSISS4_01133		HSISS4_RS05850	1227068	1227829	-	sortase		gene	gene1169	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05850
HSISS4_RS05855	HSISS4_01134		HSISS4_RS05855	1227829	1230297	-	DNA gyrase subunit A		gene	gene1170	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05855
HSISS4_RS05860	HSISS4_01135		HSISS4_RS05860	1230518	1231504	+	L-lactate dehydrogenase		gene	gene1171	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05860
HSISS4_RS05865	HSISS4_01136		HSISS4_RS05865	1231599	1232972	-	NADH oxidase (H(2)O-forming)		gene	gene1172	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05865
HSISS4_RS05870	HSISS4_01137		HSISS4_RS05870	1233262	1234800	-	ABC transporter ATP-binding protein		gene	gene1173	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05870
HSISS4_RS05875	HSISS4_01138		HSISS4_RS05875	1234939	1235469	-	substrate-specific component PdxU of pyridoxine ECF transporter		gene	gene1174	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05875
HSISS4_RS05880	HSISS4_01139		HSISS4_RS05880	1235459	1236316	-	pyridoxal kinase		gene	gene1175	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05880
HSISS4_RS05885	HSISS4_01140		HSISS4_RS05885	1236317	1236826	-	membrane protein		gene	gene1176	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05885
HSISS4_RS05890	HSISS4_01141		HSISS4_RS05890	1236964	1237494	-	hypothetical protein		gene	gene1177	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05890
HSISS4_RS05895	HSISS4_01142		HSISS4_RS05895	1237654	1238919	+	transcriptional regulator		gene	gene1178	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05895
HSISS4_RS05900	HSISS4_01143		HSISS4_RS05900	1238959	1239297	-	hypothetical protein		gene	gene1179	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05900
HSISS4_RS05905	HSISS4_01144		HSISS4_RS05905	1239389	1239970	-	hypothetical protein		gene	gene1180	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05905
HSISS4_RS05910	HSISS4_01145		HSISS4_RS05910	1240039	1242447	-	phenylalanine--tRNA ligase subunit beta		gene	gene1181	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05910
HSISS4_RS05915	HSISS4_01146		HSISS4_RS05915	1242750	1243268	-	GNAT family acetyltransferase		gene	gene1182	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05915
HSISS4_RS05920	HSISS4_01147	pheS	pheS	1243285	1244328	-	phenylalanine--tRNA ligase subunit alpha	catalyzes a two-step reaction%2C first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B forms a heterotetramer of alpha(2)beta(2)%3B binds two magnesium ions per tetramer%3B type 1 subfamily	gene	gene1183	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05920
HSISS4_RS05925	HSISS4_01148		HSISS4_RS05925	1244761	1244958	+	transcriptional regulator		gene	gene1184	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05925
HSISS4_RS05930	HSISS4_01149		HSISS4_RS05930	1244985	1245530	+	hypothetical protein		gene	gene1185	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05930
HSISS4_RS05935	HSISS4_01150		HSISS4_RS05935	1245921	1249454	-	chromosome segregation protein SMC		gene	gene1186	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05935
HSISS4_RS05940	HSISS4_01151		HSISS4_RS05940	1249457	1250146	-	ribonuclease III		gene	gene1187	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05940
HSISS4_RS05945	HSISS4_01152		HSISS4_RS05945	1250308	1251243	-	4-hydroxy-tetrahydrodipicolinate synthase		gene	gene1188	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05945
HSISS4_RS05950	HSISS4_01153		HSISS4_RS05950	1251627	1252703	-	aspartate-semialdehyde dehydrogenase	catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde	gene	gene1189	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05950
HSISS4_RS05955	HSISS4_01154		HSISS4_RS05955	1253025	1253912	-	LisH domain-containing protein		gene	gene1190	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05955
HSISS4_RS05960	HSISS4_01155		HSISS4_RS05960	1253986	1255560	-	cardiolipin synthase		gene	gene1191	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05960
HSISS4_RS05965	HSISS4_01156		HSISS4_RS05965	1255690	1256202	-	phosphinothricin N-acetyltransferase		gene	gene1192	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05965
HSISS4_RS05970	HSISS4_01157		HSISS4_RS05970	1256283	1257632	-	cardiolipin synthase		gene	gene1193	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05970
HSISS4_RS05975	HSISS4_01158		HSISS4_RS05975	1258553	1258876	+	ion channel		gene	gene1194	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05975
HSISS4_RS05980	HSISS4_RS05980		HSISS4_RS05980	1258847	1259128	-	replication protein		gene	gene1195	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05980
HSISS4_RS05985	HSISS4_01159		HSISS4_RS05985	1259441	1261225	-	excinuclease ABC subunit C		gene	gene1196	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05985
HSISS4_RS05990	HSISS4_01160		HSISS4_RS05990	1261297	1261992	-	5'-nucleotidase YjjG		gene	gene1197	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05990
HSISS4_RS05995	HSISS4_01161		HSISS4_RS05995	1262268	1262939	+	serine dehydratase subunit beta		gene	gene1198	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS05995
HSISS4_RS06000	HSISS4_01162		HSISS4_RS06000	1262952	1263821	+	L-serine dehydratase subunit alpha		gene	gene1199	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06000
HSISS4_RS06005	HSISS4_01163		HSISS4_RS06005	1263905	1267816	-	sucrose-6-phosphate hydrolase		gene	gene1200	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06005
HSISS4_RS06010	HSISS4_01164		HSISS4_RS06010	1268071	1268991	-	hypothetical protein		gene	gene1201	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06010
HSISS4_RS06015	HSISS4_01165		HSISS4_RS06015	1269116	1269655	-	RDD family protein		gene	gene1202	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06015
HSISS4_RS06020	HSISS4_01166		HSISS4_RS06020	1269854	1270774	+	transcriptional regulator		gene	gene1203	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06020
HSISS4_RS06025	HSISS4_01167		HSISS4_RS06025	1270847	1271683	+	ABC transporter ATP-binding protein		gene	gene1204	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06025
HSISS4_RS06030	HSISS4_01168		HSISS4_RS06030	1271676	1272395	+	hypothetical protein		gene	gene1205	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06030
HSISS4_RS06035	HSISS4_01169		HSISS4_RS06035	1272551	1273462	+	transcriptional regulator		gene	gene1206	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06035
HSISS4_RS06040	HSISS4_01170		HSISS4_RS06040	1273826	1274338	-	NAD(P)H oxidoreductase		gene	gene1207	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06040
HSISS4_RS06045	HSISS4_01172		HSISS4_RS06045	1274995	1281489	-	serine protease		gene	gene1208	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06045
HSISS4_RS06050	HSISS4_01173		HSISS4_RS06050	1282174	1282635	-	GNAT family acetyltransferase		gene	gene1209	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06050
HSISS4_RS06055	HSISS4_01174		HSISS4_RS06055	1282674	1283459	-	multidrug ABC transporter permease		gene	gene1210	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06055
HSISS4_RS06060	HSISS4_01175		HSISS4_RS06060	1283461	1284279	-	antibiotic ABC transporter permease		gene	gene1211	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06060
HSISS4_RS06065	HSISS4_01176		HSISS4_RS06065	1284281	1285273	-	daunorubicin resistance ATP-binding protein		gene	gene1212	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06065
HSISS4_RS06070	HSISS4_01177		HSISS4_RS06070	1285868	1286470	-	DNA-binding response regulator		gene	gene1213	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06070
HSISS4_RS06075	HSISS4_01178		HSISS4_RS06075	1286467	1287561	-	histidine kinase		gene	gene1214	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06075
HSISS4_RS06080	HSISS4_01179		HSISS4_RS06080	1287554	1288291	-	ABC transporter permease		gene	gene1215	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06080
HSISS4_RS06085	HSISS4_01180		HSISS4_RS06085	1288288	1289169	-	ABC transporter ATP-binding protein		gene	gene1216	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06085
HSISS4_RS06090	HSISS4_01181		HSISS4_RS06090	1289162	1289341	-	hypothetical protein		gene	gene1217	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06090
HSISS4_RS06095	HSISS4_01182		HSISS4_RS06095	1289352	1289561	-	hypothetical protein		gene	gene1218	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06095
HSISS4_RS06100	HSISS4_01183		HSISS4_RS06100	1289993	1290931	-	Na+-dependent transporter		gene	gene1219	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06100
HSISS4_RS06105	HSISS4_01184		HSISS4_RS06105	1291074	1291523	-	cytidine deaminase		gene	gene1220	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06105
HSISS4_RS06110	HSISS4_01185		HSISS4_RS06110	1291534	1292271	-	ABC transporter permease		gene	gene1221	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06110
HSISS4_RS06115	HSISS4_01186		HSISS4_RS06115	1292268	1293149	-	ABC transporter ATP-binding protein		gene	gene1222	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06115
HSISS4_RS06120	HSISS4_01187		HSISS4_RS06120	1293220	1293897	-	hypothetical protein		gene	gene1223	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06120
HSISS4_RS06125	HSISS4_01188		HSISS4_RS06125	1294036	1294701	-	hypothetical protein		gene	gene1224	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06125
HSISS4_RS06130	HSISS4_01189		HSISS4_RS06130	1294714	1295208	-	Fe-S oxidoreductase		gene	gene1225	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06130
HSISS4_RS06135	HSISS4_01190		HSISS4_RS06135	1295293	1297293	-	peptide ABC transporter permease		gene	gene1226	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06135
HSISS4_RS06140	HSISS4_01191		HSISS4_RS06140	1297295	1298053	-	ABC transporter ATP-binding protein		gene	gene1227	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06140
HSISS4_RS06145	HSISS4_01192		HSISS4_RS06145	1298198	1299169	-	histidine kinase		gene	gene1228	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06145
HSISS4_RS06150	HSISS4_01193		HSISS4_RS06150	1299162	1299842	-	DNA-binding response regulator		gene	gene1229	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06150
HSISS4_RS06155	HSISS4_01195		HSISS4_RS06155	1300291	1300872	+	xanthine phosphoribosyltransferase	Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine	gene	gene1230	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06155
HSISS4_RS06160	HSISS4_01196		HSISS4_RS06160	1300872	1302140	+	xanthine permease		gene	gene1231	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06160
HSISS4_RS06165	HSISS4_01197		HSISS4_RS06165	1302203	1303042	-	transposase		gene	gene1232	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06165
HSISS4_RS06170	HSISS4_01198		HSISS4_RS06170	1303018	1303554	-	transposase		gene	gene1233	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06170
HSISS4_RS06175	HSISS4_01199		HSISS4_RS06175	1303634	1304050	-	pyridoxamine 5'-phosphate oxidase		gene	gene1234	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06175
HSISS4_RS06180	HSISS4_01200		HSISS4_RS06180	1304222	1305571	+	multi antimicrobial extrusion protein (Na+/drugantiporter)		gene	gene1235	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06180
HSISS4_RS06185	HSISS4_01201		HSISS4_RS06185	1305746	1305955	-	hypothetical protein		gene	gene1236	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06185
HSISS4_RS06190	HSISS4_RS06190		HSISS4_RS06190	1306457	1307408	-	peptide methionine sulfoxide reductase	frameshifted	gene	gene1237	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06190
HSISS4_RS06195	HSISS4_01204		HSISS4_RS06195	1307543	1308871	-	branched-chain amino acid ABC transporter substrate-binding protein		gene	gene1238	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06195
HSISS4_RS06200	HSISS4_01205		HSISS4_RS06200	1309087	1310028	-	mannose-6-phosphate isomerase		gene	gene1239	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06200
HSISS4_RS06205	HSISS4_01206		HSISS4_RS06205	1310406	1310858	+	hypothetical protein		gene	gene1240	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06205
HSISS4_RS06210	HSISS4_01207		HSISS4_RS06210	1310855	1311487	+	hypothetical protein		gene	gene1241	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06210
HSISS4_RS06215	HSISS4_01208		HSISS4_RS06215	1311554	1311751	+	hypothetical protein		gene	gene1242	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06215
HSISS4_RS06220	HSISS4_01209		HSISS4_RS06220	1311823	1314369	-	hypothetical protein		gene	gene1243	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06220
HSISS4_RS06225	HSISS4_RS06225		HSISS4_RS06225	1314491	1314933	-	RNA-binding protein	frameshifted%3B internal stop	gene	gene1244	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06225
HSISS4_RS06230	HSISS4_01211		HSISS4_RS06230	1315007	1316392	-	hypothetical protein		gene	gene1245	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06230
HSISS4_RS06235	HSISS4_01212		HSISS4_RS06235	1316718	1319867	+	hypothetical protein		gene	gene1246	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06235
HSISS4_RS06240	HSISS4_01213		HSISS4_RS06240	1320006	1320488	+	glutathione peroxidase		gene	gene1247	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06240
HSISS4_RS06245	HSISS4_01214		HSISS4_RS06245	1320596	1320856	-	membrane protein		gene	gene1248	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06245
HSISS4_RS06250	HSISS4_01215		HSISS4_RS06250	1321151	1322296	-	ABC transporter permease		gene	gene1249	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06250
HSISS4_RS06255	HSISS4_01216		HSISS4_RS06255	1322300	1322980	-	ABC transporter ATP-binding protein		gene	gene1250	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06255
HSISS4_RS06260	HSISS4_01217		HSISS4_RS06260	1322977	1323552	-	TetR family transcriptional regulator		gene	gene1251	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06260
HSISS4_RS06265	HSISS4_01218		HSISS4_RS06265	1323701	1324624	-	aldo/keto reductase		gene	gene1252	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06265
HSISS4_RS06270	HSISS4_01219		HSISS4_RS06270	1324889	1325686	-	membrane protein		gene	gene1253	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06270
HSISS4_RS06275	HSISS4_01220		HSISS4_RS06275	1325689	1325898	-	transcriptional regulator		gene	gene1254	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06275
HSISS4_RS06280	HSISS4_01221		HSISS4_RS06280	1325912	1326214	-	aspartyl-tRNA synthetase		gene	gene1255	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06280
HSISS4_RS06285	HSISS4_01222		HSISS4_RS06285	1326706	1327308	-	nitroreductase		gene	gene1256	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06285
HSISS4_RS06290	HSISS4_01223		HSISS4_RS06290	1327432	1328289	-	glyoxalase		gene	gene1257	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06290
HSISS4_RS06295	HSISS4_01224		HSISS4_RS06295	1328425	1328874	-	Rrf2 family transcriptional regulator		gene	gene1258	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06295
HSISS4_RS06300	HSISS4_01225		HSISS4_RS06300	1329058	1329921	-	acyltransferase		gene	gene1259	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06300
HSISS4_RS06305	HSISS4_01226		HSISS4_RS06305	1329908	1331200	-	PTS fructose transporter subunit IIA		gene	gene1260	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06305
HSISS4_RS06310	HSISS4_01227		HSISS4_RS06310	1331449	1332369	+	ABC transporter		gene	gene1261	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06310
HSISS4_RS06315	HSISS4_01228		HSISS4_RS06315	1332374	1333128	+	hypothetical protein	frameshifted	gene	gene1262	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06315
HSISS4_RS06320	HSISS4_RS06320		HSISS4_RS06320	1333175	1333486	-	hypothetical protein		gene	gene1263	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06320
HSISS4_RS06325	HSISS4_01230		HSISS4_RS06325	1333894	1334769	-	two-component sensor histidine kinase		gene	gene1264	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06325
HSISS4_RS06330	HSISS4_01231		HSISS4_RS06330	1334769	1335452	-	DNA-binding response regulator		gene	gene1265	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06330
HSISS4_RS06335	HSISS4_01232		HSISS4_RS06335	1335615	1336247	-	NADH dehydrogenase		gene	gene1266	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06335
HSISS4_RS06340	HSISS4_01233		HSISS4_RS06340	1336338	1337024	-	hypothetical protein		gene	gene1267	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06340
HSISS4_RS06345	HSISS4_01234		HSISS4_RS06345	1337168	1338424	+	transposase		gene	gene1268	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06345
HSISS4_RS06350	HSISS4_01235		HSISS4_RS06350	1338548	1339390	-	aldo/keto reductase		gene	gene1269	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06350
HSISS4_RS06355	HSISS4_01236		HSISS4_RS06355	1339484	1340569	-	hypothetical protein		gene	gene1270	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06355
HSISS4_RS06360	HSISS4_01237		HSISS4_RS06360	1341142	1344159	-	beta-galactosidase		gene	gene1271	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06360
HSISS4_RS06365	HSISS4_01238		HSISS4_RS06365	1344163	1346067	-	PTS sugar transporter subunit IIA		gene	gene1272	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06365
HSISS4_RS06370	HSISS4_01239		HSISS4_RS06370	1346178	1347224	-	galactose mutarotase		gene	gene1273	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06370
HSISS4_RS06375	HSISS4_01240		HSISS4_RS06375	1347294	1348295	-	UDP-glucose 4-epimerase		gene	gene1274	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06375
HSISS4_RS06380	HSISS4_01241		HSISS4_RS06380	1348325	1349806	-	galactose-1-phosphate uridylyltransferase		gene	gene1275	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06380
HSISS4_RS06385	HSISS4_01242		HSISS4_RS06385	1349826	1350992	-	galactokinase	catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism	gene	gene1276	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06385
HSISS4_RS06390	HSISS4_01243		HSISS4_RS06390	1351133	1352128	+	LacI family transcriptional regulator		gene	gene1277	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06390
HSISS4_RS06395	HSISS4_01244		HSISS4_RS06395	1352187	1353797	-	glucan 1%2C6-alpha-glucosidase		gene	gene1278	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06395
HSISS4_RS06400	HSISS4_01245		HSISS4_RS06400	1354071	1354748	+	transposase		gene	gene1279	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06400
HSISS4_RS06405	HSISS4_01246		HSISS4_RS06405	1354745	1355710	+	integrase		gene	gene1280	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06405
HSISS4_RS06410	HSISS4_01247		HSISS4_RS06410	1356324	1357628	-	two-component sensor histidine kinase		gene	gene1281	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06410
HSISS4_RS06415	HSISS4_01248		HSISS4_RS06415	1357625	1358278	-	DNA-binding response regulator		gene	gene1282	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06415
HSISS4_RS06420	HSISS4_01249		HSISS4_RS06420	1358350	1359726	-	peptide ABC transporter permease		gene	gene1283	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06420
HSISS4_RS06425	HSISS4_01250		HSISS4_RS06425	1359740	1360372	-	ABC transporter ATP-binding protein		gene	gene1284	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06425
HSISS4_RS06430	HSISS4_01251		HSISS4_RS06430	1360388	1361647	-	ABC transporter membrane-spanning permease Pepexport Vex1		gene	gene1285	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06430
HSISS4_RS06435	HSISS4_01252		HSISS4_RS06435	1361954	1363438	+	hypothetical protein		gene	gene1286	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06435
HSISS4_RS06440	HSISS4_01253		HSISS4_RS06440	1363660	1364004	-	hypothetical protein		gene	gene1287	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06440
HSISS4_RS06445	HSISS4_01254		HSISS4_RS06445	1364307	1365398	-	glycerol dehydrogenase		gene	gene1288	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06445
HSISS4_RS06450	HSISS4_01255		HSISS4_RS06450	1365542	1366525	-	dehydrogenase		gene	gene1289	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06450
HSISS4_RS06455	HSISS4_01256		HSISS4_RS06455	1366540	1366914	-	phosphoenolpyruvate-dihydroxyacetone phosphotransferase subunit DhaMDHA IIA component	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene1290	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06455
HSISS4_RS06460	HSISS4_01257		HSISS4_RS06460	1366918	1367493	-	phosphoenolpyruvate-dihydroxyacetone phosphotransferase ADP-bindingsubunit DhaL		gene	gene1291	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06460
HSISS4_RS06465	HSISS4_01258		HSISS4_RS06465	1367525	1368514	-	dihydroxyacetone kinase subunit DhaK	with DhaL and DhaM forms dihydroxyacetone kinase%2C which is responsible for phosphorylating dihydroxyacetone%3B DhaK is the dihydroxyacetone binding subunit of the dihydroxyacetone kinase	gene	gene1292	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06465
HSISS4_RS06470	HSISS4_01259		HSISS4_RS06470	1368841	1370106	+	hypothetical protein		gene	gene1293	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06470
HSISS4_RS06475	HSISS4_01260		HSISS4_RS06475	1370209	1371042	-	diadenosine tetraphosphatase and related serine/threonine protein phosphatase		gene	gene1294	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06475
HSISS4_RS06480	HSISS4_01261		HSISS4_RS06480	1371093	1371416	-	hypothetical protein		gene	gene1295	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06480
HSISS4_RS06485	HSISS4_01262		HSISS4_RS06485	1371406	1372011	-	hemolysis inducing protein		gene	gene1296	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06485
HSISS4_RS06490	HSISS4_01263		HSISS4_RS06490	1372001	1372276	-	transcriptional regulator		gene	gene1297	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06490
HSISS4_RS06495	HSISS4_01264		HSISS4_RS06495	1372254	1373000	-	hypothetical protein		gene	gene1298	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06495
HSISS4_RS06500	HSISS4_01265		HSISS4_RS06500	1373202	1373528	-	hypothetical protein		gene	gene1299	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06500
HSISS4_RS06505	HSISS4_01266		HSISS4_RS06505	1373801	1378540	-	glucosyltransferase		gene	gene1300	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06505
HSISS4_RS06510	HSISS4_01267		HSISS4_RS06510	1378925	1379071	-	glucosyl transferase		gene	gene1301	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06510
HSISS4_RS06515	HSISS4_01268		HSISS4_RS06515	1379405	1381390	-	hypothetical protein		gene	gene1302	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06515
HSISS4_RS06520	HSISS4_01269		HSISS4_RS06520	1381872	1386557	-	hypothetical protein		gene	gene1303	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06520
HSISS4_RS06525	HSISS4_01270		HSISS4_RS06525	1386806	1387771	-	integrase		gene	gene1304	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06525
HSISS4_RS06530	HSISS4_01271		HSISS4_RS06530	1387768	1388445	-	transposase		gene	gene1305	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06530
HSISS4_RS06535	HSISS4_01272		HSISS4_RS06535	1388629	1389102	-	transposase		gene	gene1306	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06535
HSISS4_RS06540	HSISS4_01273		HSISS4_RS06540	1389634	1390965	+	choline-binding protein A		gene	gene1307	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06540
HSISS4_RS06545	HSISS4_01274		HSISS4_RS06545	1391166	1394348	+	hypothetical protein		gene	gene1308	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06545
HSISS4_RS06550	HSISS4_01275		HSISS4_RS06550	1395080	1397935	+	glucosyl transferase		gene	gene1309	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06550
HSISS4_RS06555	HSISS4_01276		HSISS4_RS06555	1397993	1401556	+	glucosyl transferase		gene	gene1310	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06555
HSISS4_RS06560	HSISS4_01277		HSISS4_RS06560	1401611	1404142	+	glucosyl transferase		gene	gene1311	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06560
HSISS4_RS06565	HSISS4_01278		HSISS4_RS06565	1404872	1407307	+	glucosyl transferase	internal stop	gene	gene1312	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06565
HSISS4_RS06570	HSISS4_01280		HSISS4_RS06570	1407561	1408154	-	glutamine amidotransferase subunit PdxT		gene	gene1313	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06570
HSISS4_RS06575	HSISS4_01281		HSISS4_RS06575	1408155	1409027	-	pyridoxal biosynthesis lyase PdxS	with PdxT forms pyridoxal 5'-phosphate from glutamine%2C either ribose 5-phosphate or ribulose 5-phosphate%2C and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate	gene	gene1314	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06575
HSISS4_RS06580	HSISS4_01282		HSISS4_RS06580	1409358	1412156	+	hypothetical protein		gene	gene1315	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06580
HSISS4_RS06585	HSISS4_01283		HSISS4_RS06585	1412471	1414414	+	hypothetical protein		gene	gene1316	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06585
HSISS4_RS06590	HSISS4_01284		HSISS4_RS06590	1414694	1417786	+	hypothetical protein		gene	gene1317	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06590
HSISS4_RS06595	HSISS4_01285		HSISS4_RS06595	1418090	1420330	+	hypothetical protein		gene	gene1318	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06595
HSISS4_RS06600	HSISS4_01286		HSISS4_RS06600	1420597	1423458	+	hypothetical protein		gene	gene1319	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06600
HSISS4_RS06605	HSISS4_01287		HSISS4_RS06605	1423844	1426369	+	glucosyl transferase		gene	gene1320	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06605
HSISS4_RS06610	HSISS4_01288		HSISS4_RS06610	1426479	1427492	-	hypothetical protein		gene	gene1321	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06610
HSISS4_RS06615	HSISS4_01289		HSISS4_RS06615	1427732	1430257	-	hypothetical protein		gene	gene1322	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06615
HSISS4_RS06620	HSISS4_01290		HSISS4_RS06620	1430276	1431223	-	malate permease		gene	gene1323	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06620
HSISS4_RS06625	HSISS4_01291		HSISS4_RS06625	1431307	1432932	-	Malolactic enzyme	malic enzyme%3B oxaloacetate-decarboxylating%3B NAD-dependent%3B catalyzes the formation of pyruvate form malate	gene	gene1324	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06625
HSISS4_RS06630	HSISS4_01292		HSISS4_RS06630	1433107	1433457	+	transcriptional regulator		gene	gene1325	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06630
HSISS4_RS06635	HSISS4_01293		HSISS4_RS06635	1433598	1434473	+	Malolactic regulator		gene	gene1326	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06635
HSISS4_RS06640	HSISS4_01294		HSISS4_RS06640	1434632	1435597	-	integrase		gene	gene1327	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06640
HSISS4_RS06645	HSISS4_01295		HSISS4_RS06645	1435594	1436271	-	transposase		gene	gene1328	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06645
HSISS4_RS06650	HSISS4_01296		HSISS4_RS06650	1436455	1436928	-	transposase		gene	gene1329	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06650
HSISS4_RS06655	HSISS4_01297		HSISS4_RS06655	1437099	1437857	-	hypothetical protein		gene	gene1330	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06655
HSISS4_RS06660	HSISS4_01298		HSISS4_RS06660	1438024	1439409	-	MFS transporter		gene	gene1331	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06660
HSISS4_RS06665	HSISS4_01299		HSISS4_RS06665	1439435	1439845	-	MarR family transcriptional regulator		gene	gene1332	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06665
HSISS4_RS06670	HSISS4_01300		HSISS4_RS06670	1439968	1440531	-	maltose O-acetyltransferase		gene	gene1333	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06670
HSISS4_RS06675	HSISS4_01301		HSISS4_RS06675	1440636	1441385	-	hypothetical protein		gene	gene1334	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06675
HSISS4_RS06680	HSISS4_01302		HSISS4_RS06680	1441655	1445638	-	glutamine amidotransferase		gene	gene1335	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06680
HSISS4_RS06685	HSISS4_01303		HSISS4_RS06685	1446417	1450772	-	glucosyltransferase		gene	gene1336	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06685
HSISS4_RS06690	HSISS4_01304		HSISS4_RS06690	1451400	1451843	+	hypothetical protein		gene	gene1337	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06690
HSISS4_RS06695	HSISS4_01305		HSISS4_RS06695	1452191	1457293	-	flagellar biosynthesis protein FliS	incomplete%3B partial in the middle of a contig%3B missing stop	gene	gene1338	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06695
HSISS4_RS06700	HSISS4_01306		HSISS4_RS06700	1457567	1460908	-	hypothetical protein		gene	gene1339	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06700
HSISS4_RS06705	HSISS4_01307		HSISS4_RS06705	1461427	1462176	-	muramidase	incomplete%3B partial in the middle of a contig%3B missing start	gene	gene1340	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06705
HSISS4_RS06710	HSISS4_01308		HSISS4_RS06710	1462265	1462807	+	hypothetical protein		gene	gene1341	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06710
HSISS4_RS06715	HSISS4_RS06715		HSISS4_RS06715	1462794	1463507	-	muramidase	incomplete%3B partial in the middle of a contig%3B missing start and stop	gene	gene1342	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06715
HSISS4_RS06720	HSISS4_01310		HSISS4_RS06720	1467139	1468140	-	nucleotide sugar synthetase	catalyzes the transfer of beta-1%2C6-galactofuranosyl to a galactopyranoside	gene	gene1343	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06720
HSISS4_RS06725	HSISS4_01312		HSISS4_RS06725	1468403	1468582	-	hypothetical protein		gene	gene1344	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06725
HSISS4_RS06730	HSISS4_01313		HSISS4_RS06730	1468575	1469927	-	accessory Sec system glycosylation chaperone GtfB		gene	gene1345	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06730
HSISS4_RS06735	HSISS4_01314		HSISS4_RS06735	1469924	1471432	-	accessory Sec system glycosyltransferase GtfA		gene	gene1346	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06735
HSISS4_RS06740	HSISS4_01315		HSISS4_RS06740	1471445	1473820	-	accessory Sec system translocase SecA2		gene	gene1347	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06740
HSISS4_RS06745	HSISS4_01316		HSISS4_RS06745	1473813	1474259	-	accessory Sec system protein Asp3		gene	gene1348	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06745
HSISS4_RS06750	HSISS4_01317		HSISS4_RS06750	1474262	1475800	-	accessory Sec system protein Asp2		gene	gene1349	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06750
HSISS4_RS06755	HSISS4_01318		HSISS4_RS06755	1475787	1477358	-	accessory Sec system protein Asp1		gene	gene1350	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06755
HSISS4_RS06760	HSISS4_01319		HSISS4_RS06760	1477459	1478685	-	accessory Sec system protein translocase subunit SecY2		gene	gene1351	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06760
HSISS4_RS06765	HSISS4_01320		HSISS4_RS06765	1478780	1480873	-	beta-1%2C3-glucosyltransferase		gene	gene1352	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06765
HSISS4_RS06770	HSISS4_01321		HSISS4_RS06770	1481258	1484437	-	exonuclease SbcC		gene	gene1353	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06770
HSISS4_RS06775	HSISS4_01322		HSISS4_RS06775	1484434	1485642	-	exonuclease sbcCD subunit D		gene	gene1354	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06775
HSISS4_RS06780	HSISS4_01323		HSISS4_RS06780	1485826	1489470	-	YSIRK signal domain/LPXTG anchor domain surface protein		gene	gene1355	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06780
HSISS4_RS06785	HSISS4_01324		HSISS4_RS06785	1489930	1496085	-	YSIRK signal domain/LPXTG anchor domain surface protein		gene	gene1356	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06785
HSISS4_RS06790	HSISS4_01325		HSISS4_RS06790	1496542	1509507	-	fibronectin-binding protein		gene	gene1357	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06790
HSISS4_RS06795	HSISS4_01326		HSISS4_RS06795	1510036	1511124	-	hypothetical protein		gene	gene1358	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06795
HSISS4_RS06800	HSISS4_01327		HSISS4_RS06800	1511562	1513085	+	ABC transporter ATP-binding protein		gene	gene1359	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06800
HSISS4_RS06805	HSISS4_01328		HSISS4_RS06805	1513181	1515049	-	Lipid A export ATP-binding/permease MsbA		gene	gene1360	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06805
HSISS4_RS06810	HSISS4_01329		HSISS4_RS06810	1515039	1516784	-	Lipid A export ATP-binding/permease MsbA		gene	gene1361	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06810
HSISS4_RS06815	HSISS4_01330		HSISS4_RS06815	1517648	1519912	+	bifunctional glutamate--cysteine ligase/glutathione synthetase	Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine	gene	gene1362	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06815
HSISS4_RS06820	HSISS4_01331		HSISS4_RS06820	1519974	1520570	-	hypothetical protein		gene	gene1363	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06820
HSISS4_RS06825	HSISS4_01332		HSISS4_RS06825	1520551	1522080	-	hypothetical protein		gene	gene1364	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06825
HSISS4_RS06830	HSISS4_01333		HSISS4_RS06830	1522188	1522748	-	hypothetical protein		gene	gene1365	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06830
HSISS4_RS06835	HSISS4_01334		HSISS4_RS06835	1522960	1525365	-	glycogen phosphorylase		gene	gene1366	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06835
HSISS4_RS06840	HSISS4_01335		HSISS4_RS06840	1525691	1527121	-	starch synthase		gene	gene1367	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06840
HSISS4_RS06845	HSISS4_01336		HSISS4_RS06845	1527118	1528254	-	glycogen biosynthesis protein GlgD%2C glucose-1-phosphate adenylyltransferase family		gene	gene1368	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06845
HSISS4_RS06850	HSISS4_01337	glgC	glgC	1528244	1529386	-	glucose-1-phosphate adenylyltransferase	catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate	gene	gene1369	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06850
HSISS4_RS06855	HSISS4_01338		HSISS4_RS06855	1529577	1531457	-	1%2C4-alpha-glucan branching enzyme	catalyzes the transfer of a segment of a 1%2C4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain	gene	gene1370	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06855
HSISS4_RS06860	HSISS4_01339		HSISS4_RS06860	1531627	1533822	-	Glycogen debranching enzyme /Pullulanase		gene	gene1371	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06860
HSISS4_RS06865	HSISS4_01340		HSISS4_RS06865	1534037	1536451	-	cell division protein FtsK		gene	gene1372	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06865
HSISS4_RS06870	HSISS4_01341		HSISS4_RS06870	1536534	1537532	-	thioredoxin reductase	catalyzes the oxidation of ferredoxin with NADP	gene	gene1373	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06870
HSISS4_RS06875	HSISS4_01342		HSISS4_RS06875	1537534	1538253	-	tRNA (guanine-N(1)-)-methyltransferase		gene	gene1374	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06875
HSISS4_RS06880	HSISS4_01343		HSISS4_RS06880	1538243	1538761	-	ribosome maturation factor RimM		gene	gene1375	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06880
HSISS4_RS06885	HSISS4_r00059		HSISS4_RS06885	1538982	1539053	-	tRNA-Glu		tRNA	gene1376	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06885
HSISS4_RS06890	HSISS4_r00060		HSISS4_RS06890	1539083	1539154	-	tRNA-Gln		tRNA	gene1377	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06890
HSISS4_RS06895	HSISS4_01344		HSISS4_RS06895	1539457	1540101	-	DNA-binding response regulator		gene	gene1378	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06895
HSISS4_RS06900	HSISS4_01345		HSISS4_RS06900	1540091	1541101	-	two-component sensor histidine kinase		gene	gene1379	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06900
HSISS4_RS06905	HSISS4_01346		HSISS4_RS06905	1541098	1541796	-	transporter		gene	gene1380	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06905
HSISS4_RS06910	HSISS4_01347		HSISS4_RS06910	1541959	1542717	-	hypothetical protein		gene	gene1381	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06910
HSISS4_RS06915	HSISS4_01348		HSISS4_RS06915	1542865	1544739	-	serine/threonine protein kinase		gene	gene1382	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06915
HSISS4_RS06920	HSISS4_01349		HSISS4_RS06920	1544739	1545476	-	protein phosphatase		gene	gene1383	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06920
HSISS4_RS06925	HSISS4_01350		HSISS4_RS06925	1545520	1546842	-	16S rRNA methyltransferase		gene	gene1384	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06925
HSISS4_RS06930	HSISS4_01351		HSISS4_RS06930	1546832	1547767	-	methionyl-tRNA formyltransferase		gene	gene1385	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06930
HSISS4_RS06935	HSISS4_01352		HSISS4_RS06935	1547785	1550181	-	primosomal protein N'		gene	gene1386	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06935
HSISS4_RS06940	HSISS4_01353		HSISS4_RS06940	1550324	1550638	-	DNA-directed RNA polymerase subunit omega		gene	gene1387	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06940
HSISS4_RS06945	HSISS4_01354		HSISS4_RS06945	1550660	1551289	-	guanylate kinase		gene	gene1388	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06945
HSISS4_RS06950	HSISS4_01355		HSISS4_RS06950	1551524	1552921	-	signal recognition particle-docking protein FtsY		gene	gene1389	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06950
HSISS4_RS06955	HSISS4_01356		HSISS4_RS06955	1552932	1553750	-	phosphatase		gene	gene1390	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06955
HSISS4_RS06960	HSISS4_01357		HSISS4_RS06960	1553743	1554537	-	haloacid dehalogenase		gene	gene1391	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06960
HSISS4_RS06965	HSISS4_01358		HSISS4_RS06965	1554719	1555096	+	GntR family transcriptional regulator		gene	gene1392	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06965
HSISS4_RS06970	HSISS4_01359		HSISS4_RS06970	1555101	1555799	+	multidrug ABC transporter ATPase		gene	gene1393	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06970
HSISS4_RS06975	HSISS4_01360		HSISS4_RS06975	1555811	1556596	+	ABC transporter ATP-binding protein		gene	gene1394	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06975
HSISS4_RS06980	HSISS4_01361		HSISS4_RS06980	1556648	1557577	-	Oligopeptide transport ATP-binding protein OppF		gene	gene1395	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06980
HSISS4_RS06985	HSISS4_01362		HSISS4_RS06985	1557570	1558655	-	Oligopeptide transport ATP-binding protein OppD		gene	gene1396	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06985
HSISS4_RS06990	HSISS4_01363		HSISS4_RS06990	1558665	1559591	-	peptide ABC transporter permease		gene	gene1397	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06990
HSISS4_RS06995	HSISS4_01364		HSISS4_RS06995	1559591	1561084	-	peptide ABC transporter permease		gene	gene1398	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS06995
HSISS4_RS07000	HSISS4_01365		HSISS4_RS07000	1561145	1563115	-	peptide ABC transporter ATP-binding protein		gene	gene1399	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07000
HSISS4_RS07005	HSISS4_01366		HSISS4_RS07005	1563297	1565267	-	peptide ABC transporter substrate-binding protein		gene	gene1400	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07005
HSISS4_RS07010	HSISS4_01367	eutD	eutD	1565503	1566486	-	phosphate acetyltransferase	in Salmonella this enzyme is required for ethanolamine catabolism%3B has higher affinity for CoA than Pta	gene	gene1401	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07010
HSISS4_RS07015	HSISS4_01368		HSISS4_RS07015	1566500	1567396	-	ribosomal large subunit pseudouridine synthase D%2C YjbO type		gene	gene1402	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07015
HSISS4_RS07020	HSISS4_01369		HSISS4_RS07020	1567393	1568229	-	NAD(+) kinase		gene	gene1403	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07020
HSISS4_RS07025	HSISS4_01370		HSISS4_RS07025	1568201	1568875	-	GTP pyrophosphokinase		gene	gene1404	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07025
HSISS4_RS07030	HSISS4_01371		HSISS4_RS07030	1568971	1569546	+	adenylate cyclase		gene	gene1405	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07030
HSISS4_RS07035	HSISS4_01372		HSISS4_RS07035	1569820	1570791	+	ribose-phosphate diphosphokinase	catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP	gene	gene1406	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07035
HSISS4_RS07040	HSISS4_01373		HSISS4_RS07040	1570795	1571907	+	hypothetical protein		gene	gene1407	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07040
HSISS4_RS07045	HSISS4_01374		HSISS4_RS07045	1571909	1572256	+	cysteine desulfurase		gene	gene1408	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07045
HSISS4_RS07050	HSISS4_01375		HSISS4_RS07050	1572398	1573057	+	redox-sensing transcriptional repressor Rex		gene	gene1409	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07050
HSISS4_RS07055	HSISS4_01376		HSISS4_RS07055	1573050	1573745	+	glutamine amidotransferase		gene	gene1410	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07055
HSISS4_RS07060	HSISS4_01377		HSISS4_RS07060	1573803	1574489	-	hypothetical protein		gene	gene1411	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07060
HSISS4_RS07065	HSISS4_01378		HSISS4_RS07065	1574540	1576324	-	alpha-L-Rha alpha-1%2C2-L-rhamnosyltransferase		gene	gene1412	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07065
HSISS4_RS07070	HSISS4_01379		HSISS4_RS07070	1576321	1577355	-	glycosyl transferase		gene	gene1413	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07070
HSISS4_RS07075	HSISS4_01380		HSISS4_RS07075	1577375	1578580	-	ABC transporter ATP-binding protein		gene	gene1414	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07075
HSISS4_RS07080	HSISS4_01381		HSISS4_RS07080	1578580	1579389	-	rhamnose-containing polysaccharide translocation permease		gene	gene1415	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07080
HSISS4_RS07085	HSISS4_01382		HSISS4_RS07085	1579373	1580329	-	alpha-L-Rha alpha-1%2C2-L-rhamnosyltransferase		gene	gene1416	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07085
HSISS4_RS07090	HSISS4_01383		HSISS4_RS07090	1580326	1581474	-	alpha-D-GlcNAc alpha-1%2C2-L-rhamnosyl transferase		gene	gene1417	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07090
HSISS4_RS07095	HSISS4_01384		HSISS4_RS07095	1581581	1583122	-	membrane protein		gene	gene1418	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07095
HSISS4_RS07100	HSISS4_01385		HSISS4_RS07100	1583129	1584139	-	hypothetical protein		gene	gene1419	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07100
HSISS4_RS07105	HSISS4_01386		HSISS4_RS07105	1584136	1585413	-	Heteropolysaccharide repeat unit exportprotein		gene	gene1420	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07105
HSISS4_RS07110	HSISS4_01387		HSISS4_RS07110	1585406	1585738	-	glycosyl transferase		gene	gene1421	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07110
HSISS4_RS07115	HSISS4_01388		HSISS4_RS07115	1585744	1586433	-	glycosyl transferase group 2		gene	gene1422	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07115
HSISS4_RS07120	HSISS4_01389		HSISS4_RS07120	1586514	1587365	-	NAD(P)-dependent oxidoreductase		gene	gene1423	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07120
HSISS4_RS07125	HSISS4_01390		HSISS4_RS07125	1587444	1588778	-	hypothetical protein		gene	gene1424	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07125
HSISS4_RS07130	HSISS4_01391		HSISS4_RS07130	1588891	1589817	-	bactoprenol glucosyl transferase		gene	gene1425	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07130
HSISS4_RS07135	HSISS4_01392		HSISS4_RS07135	1589828	1590163	-	aromatic ring hydroxylating protein		gene	gene1426	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07135
HSISS4_RS07140	HSISS4_01393		HSISS4_RS07140	1590217	1591326	-	RNA polymerase sigma factor RpoD		gene	gene1427	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07140
HSISS4_RS07145	HSISS4_01394		HSISS4_RS07145	1591330	1593141	-	DNA primase		gene	gene1428	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07145
HSISS4_RS07150	HSISS4_01395	mscL	mscL	1593304	1593684	+	large-conductance mechanosensitive channel	homopentamer%3B channel that opens in response to pressure or hypoosmotic shock	gene	gene1429	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07150
HSISS4_RS07155	HSISS4_01396		HSISS4_RS07155	1593843	1594019	-	30S ribosomal protein S21		gene	gene1430	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07155
HSISS4_RS07160	HSISS4_01397		HSISS4_RS07160	1594214	1595008	-	amino acid ABC transporter substrate-binding protein		gene	gene1431	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07160
HSISS4_RS07165	HSISS4_01398		HSISS4_RS07165	1595070	1596179	-	aspartate aminotransferase	associated with arginine deiminase pathway genes%3B probably functions in arginine catabolism	gene	gene1432	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07165
HSISS4_RS07170	HSISS4_01399		HSISS4_RS07170	1596425	1597222	-	polar amino acid ABC uptake transporter substrate-binding protein		gene	gene1433	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07170
HSISS4_RS07175	HSISS4_01400		HSISS4_RS07175	1597234	1598046	-	polar amino acid ABC uptake transporter substrate-binding protein		gene	gene1434	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07175
HSISS4_RS07180	HSISS4_01401		HSISS4_RS07180	1598261	1598725	-	DNA mismatch repair protein MutT		gene	gene1435	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07180
HSISS4_RS07185	HSISS4_RS07185		HSISS4_RS07185	1598768	1599079	-	hypothetical protein		gene	gene1436	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07185
HSISS4_RS07190	HSISS4_01402		HSISS4_RS07190	1599241	1601232	-	excinuclease ABC subunit B	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands%2C where it probes for the presence of a lesion	gene	gene1437	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07190
HSISS4_RS07195	HSISS4_01403		HSISS4_RS07195	1601222	1601848	-	hypothetical protein		gene	gene1438	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07195
HSISS4_RS07200	HSISS4_01404		HSISS4_RS07200	1601917	1602852	-	CAAX amino protease		gene	gene1439	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07200
HSISS4_RS07205	HSISS4_01405		HSISS4_RS07205	1603051	1605249	+	glutamine ABC transporter glutamine-binding protein/permease		gene	gene1440	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07205
HSISS4_RS07210	HSISS4_01406		HSISS4_RS07210	1605249	1605989	+	peptide ABC transporter ATP-binding protein		gene	gene1441	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07210
HSISS4_RS07215	HSISS4_01407		HSISS4_RS07215	1606067	1606264	-	hypothetical protein		gene	gene1442	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07215
HSISS4_RS07220	HSISS4_01408	obgE	obgE	1606392	1607705	-	GTPase ObgE	ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication	gene	gene1443	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07220
HSISS4_RS07225	HSISS4_01410		HSISS4_RS07225	1608010	1608741	-	16S rRNA pseudouridine(516) synthase		gene	gene1444	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07225
HSISS4_RS07230	HSISS4_01411		HSISS4_RS07230	1608742	1609716	-	hypothetical protein		gene	gene1445	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07230
HSISS4_RS07235	HSISS4_01412		HSISS4_RS07235	1609730	1610113	-	phenylacetic acid degradation protein PaaD%2C thioesterase		gene	gene1446	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07235
HSISS4_RS07240	HSISS4_01413		HSISS4_RS07240	1610207	1610572	-	Salt-stress induced protein		gene	gene1447	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07240
HSISS4_RS07245	HSISS4_01414		HSISS4_RS07245	1610820	1611185	+	hypothetical protein		gene	gene1448	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07245
HSISS4_RS07250	HSISS4_01415		HSISS4_RS07250	1611301	1612191	+	drug/metabolite DMT transporter permease		gene	gene1449	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07250
HSISS4_RS07255	HSISS4_01416		HSISS4_RS07255	1612229	1612468	-	membrane protein		gene	gene1450	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07255
HSISS4_RS07260	HSISS4_01417		HSISS4_RS07260	1612695	1613342	-	phosphoserine phosphatase		gene	gene1451	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07260
HSISS4_RS07265	HSISS4_01418		HSISS4_RS07265	1613454	1615178	-	septation ring formation regulator EzrA	acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation	gene	gene1452	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07265
HSISS4_RS07270	HSISS4_01419	gyrB	gyrB	1615275	1617227	-	DNA gyrase subunit B	negatively supercoils closed circular double-stranded DNA	gene	gene1453	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07270
HSISS4_RS07275	HSISS4_01420		HSISS4_RS07275	1617228	1617788	-	DNA gyrase subunit B		gene	gene1454	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07275
HSISS4_RS07280	HSISS4_01421		HSISS4_RS07280	1617874	1618569	-	membrane protein		gene	gene1455	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07280
HSISS4_RS07285	HSISS4_01422		HSISS4_RS07285	1618562	1618936	-	murein hydrolase regulator LrgA		gene	gene1456	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07285
HSISS4_RS07290	HSISS4_r00061		HSISS4_RS07290	1619089	1619159	-	tRNA-Thr		tRNA	gene1457	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07290
HSISS4_RS07295	HSISS4_01423		HSISS4_RS07295	1619217	1619570	-	arsenate reductase		gene	gene1458	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07295
HSISS4_RS07300	HSISS4_01424		HSISS4_RS07300	1619605	1620099	-	methylated-DNA--protein-cysteine methyltransferase		gene	gene1459	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07300
HSISS4_RS07305	HSISS4_01425		HSISS4_RS07305	1620155	1621333	-	D-3-phosphoglycerate dehydrogenase		gene	gene1460	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07305
HSISS4_RS07310	HSISS4_01426		HSISS4_RS07310	1621351	1621908	-	acetyltransferase		gene	gene1461	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07310
HSISS4_RS07315	HSISS4_01427		HSISS4_RS07315	1621921	1623015	-	phosphoserine transaminase		gene	gene1462	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07315
HSISS4_RS07320	HSISS4_01428		HSISS4_RS07320	1623170	1624063	-	transcriptional regulator		gene	gene1463	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07320
HSISS4_RS07325	HSISS4_01429		HSISS4_RS07325	1624179	1624574	+	lactoylglutathione lyase		gene	gene1464	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07325
HSISS4_RS07330	HSISS4_01430		HSISS4_RS07330	1624618	1625517	-	protease		gene	gene1465	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07330
HSISS4_RS07335	HSISS4_01431		HSISS4_RS07335	1625827	1626894	-	spermidine/putrescine ABC transporter substrate-binding protein		gene	gene1466	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07335
HSISS4_RS07340	HSISS4_01432		HSISS4_RS07340	1626887	1627663	-	spermidine/purescine ABC transporter permease		gene	gene1467	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07340
HSISS4_RS07345	HSISS4_01433		HSISS4_RS07345	1627660	1628454	-	Spermidine Putrescine ABC transporter permease component PotB		gene	gene1468	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07345
HSISS4_RS07350	HSISS4_01434		HSISS4_RS07350	1628438	1629592	-	spermidine/putrescine ABC transporter ATP-binding protein		gene	gene1469	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07350
HSISS4_RS07355	HSISS4_01435	murB	murB	1629639	1630541	-	UDP-N-acetylenolpyruvoylglucosamine reductase	catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis	gene	gene1470	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07355
HSISS4_RS07360	HSISS4_01436		HSISS4_RS07360	1630731	1631222	-	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase		gene	gene1471	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07360
HSISS4_RS07365	HSISS4_01437		HSISS4_RS07365	1631219	1631578	-	dihydroneopterin aldolase		gene	gene1472	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07365
HSISS4_RS07370	HSISS4_01438		HSISS4_RS07370	1631799	1633250	+	alpha-amylase		gene	gene1473	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07370
HSISS4_RS07375	HSISS4_01439		HSISS4_RS07375	1633282	1634082	-	dihydropteroate synthase		gene	gene1474	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07375
HSISS4_RS07380	HSISS4_01440		HSISS4_RS07380	1634091	1634654	-	type I GTP cyclohydrolase I FolE		gene	gene1475	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07380
HSISS4_RS07385	HSISS4_01441		HSISS4_RS07385	1634800	1636644	-	amino acid permease		gene	gene1476	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07385
HSISS4_RS07390	HSISS4_01442		HSISS4_RS07390	1636711	1637973	-	dihydrofolate synthase Folylpolyglutamatesynthase		gene	gene1477	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07390
HSISS4_RS07395	HSISS4_01443		HSISS4_RS07395	1638136	1638384	-	RNA-binding protein		gene	gene1478	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07395
HSISS4_RS07400	HSISS4_01444	rpsP	rpsP	1638396	1638668	-	30S ribosomal protein S16	binds to lower part of 30S body where it stabilizes two domains%3B required for efficient assembly of 30S%3B in Escherichia coli this protein has nuclease activity	gene	gene1479	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07400
HSISS4_RS07405	HSISS4_01445		HSISS4_RS07405	1638831	1640210	-	hypothetical protein		gene	gene1480	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07405
HSISS4_RS07410	HSISS4_01446		HSISS4_RS07410	1640322	1641500	-	histidine kinase		gene	gene1481	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07410
HSISS4_RS07415	HSISS4_01447		HSISS4_RS07415	1641811	1642548	-	DNA-binding response regulator		gene	gene1482	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07415
HSISS4_RS07420	HSISS4_01448		HSISS4_RS07420	1642762	1644033	+	Zn-dependent protease		gene	gene1483	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07420
HSISS4_RS07425	HSISS4_01449		HSISS4_RS07425	1644447	1645325	+	tellurite resistance methyltransferase TehB	with TehA confers resistance to tellurite	gene	gene1484	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07425
HSISS4_RS07430	HSISS4_01450		HSISS4_RS07430	1645409	1646161	-	hypothetical protein		gene	gene1485	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07430
HSISS4_RS07435	HSISS4_01451		HSISS4_RS07435	1646257	1647306	-	N5%2CN10-methylene tetrahydromethanopterin reductase		gene	gene1486	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07435
HSISS4_RS07440	HSISS4_01452		HSISS4_RS07440	1647395	1647727	-	hypothetical protein		gene	gene1487	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07440
HSISS4_RS07445	HSISS4_01453		HSISS4_RS07445	1647855	1648682	+	exodeoxyribonuclease		gene	gene1488	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07445
HSISS4_RS07450	HSISS4_01454		HSISS4_RS07450	1648758	1649237	+	Substrate-specific component QueTf		gene	gene1489	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07450
HSISS4_RS07455	HSISS4_01455		HSISS4_RS07455	1649278	1650906	-	hypothetical protein		gene	gene1490	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07455
HSISS4_RS07460	HSISS4_01456		HSISS4_RS07460	1651016	1652002	-	WYL domain-containing protein		gene	gene1491	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07460
HSISS4_RS07465	HSISS4_01457		HSISS4_RS07465	1652083	1653102	-	hypothetical protein	incomplete%3B partial in the middle of a contig%3B missing start	gene	gene1492	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07465
HSISS4_RS07470	HSISS4_01458		HSISS4_RS07470	1653228	1654241	-	transcription regulator	similar to YegS from E. coli	gene	gene1493	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07470
HSISS4_RS07475	HSISS4_01459	ligA	ligA	1654251	1656209	-	DNA ligase (NAD(+)) LigA	this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB	gene	gene1494	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07475
HSISS4_RS07480	HSISS4_01460		HSISS4_RS07480	1656260	1656769	-	Substrate-specific component QueTf		gene	gene1495	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07480
HSISS4_RS07485	HSISS4_01461		HSISS4_RS07485	1656860	1657819	-	hypothetical protein		gene	gene1496	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07485
HSISS4_RS07490	HSISS4_01462		HSISS4_RS07490	1657821	1658681	-	methionine aminopeptidase	catalyzes the removal of N-terminal amino acids from peptides and arylamides	gene	gene1497	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07490
HSISS4_RS07495	HSISS4_01463		HSISS4_RS07495	1658725	1660005	-	hypothetical protein		gene	gene1498	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07495
HSISS4_RS07500	HSISS4_01464		HSISS4_RS07500	1659998	1660543	-	GNAT family acetyltransferase		gene	gene1499	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07500
HSISS4_RS07505	HSISS4_01465		HSISS4_RS07505	1660609	1661871	-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase		gene	gene1500	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07505
HSISS4_RS07510	HSISS4_01466		HSISS4_RS07510	1661957	1664197	-	Late competence protein ComEC%2C DNA transport		gene	gene1501	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07510
HSISS4_RS07515	HSISS4_01467		HSISS4_RS07515	1664187	1664882	-	Late competence protein ComEA%2C DNA receptor		gene	gene1502	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07515
HSISS4_RS07520	HSISS4_01468		HSISS4_RS07520	1664990	1665745	-	1-acyl-sn-glycerol-3-phosphate acyltransferase		gene	gene1503	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07520
HSISS4_RS07525	HSISS4_01469		HSISS4_RS07525	1665838	1666809	+	polysaccharide deacetylase		gene	gene1504	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07525
HSISS4_RS07530	HSISS4_01470		HSISS4_RS07530	1666859	1667623	+	hypothetical protein		gene	gene1505	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07530
HSISS4_RS07535	HSISS4_01471		HSISS4_RS07535	1667627	1667896	+	hypothetical protein		gene	gene1506	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07535
HSISS4_RS07540	HSISS4_01472		HSISS4_RS07540	1667953	1669539	-	RNA helicase		gene	gene1507	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07540
HSISS4_RS07545	HSISS4_01473		HSISS4_RS07545	1669734	1670639	-	magnesium and cobalt transporter CorA		gene	gene1508	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07545
HSISS4_RS07550	HSISS4_01474		HSISS4_RS07550	1670652	1671032	-	helicase		gene	gene1509	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07550
HSISS4_RS07555	HSISS4_01475		HSISS4_RS07555	1671342	1671917	+	proton-coupled thiamine transporter YuaJ		gene	gene1510	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07555
HSISS4_RS07560	HSISS4_01476		HSISS4_RS07560	1672085	1672948	+	Positive transcriptional regulator MutR family		gene	gene1511	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07560
HSISS4_RS07565	HSISS4_01477		HSISS4_RS07565	1673061	1674239	+	MFS transporter		gene	gene1512	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07565
HSISS4_RS07570	HSISS4_01478		HSISS4_RS07570	1674769	1676313	-	peptide chain release factor 3		gene	gene1513	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07570
HSISS4_RS07575	HSISS4_01479		HSISS4_RS07575	1676680	1677339	-	hypothetical protein		gene	gene1514	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07575
HSISS4_RS07580	HSISS4_01480		HSISS4_RS07580	1677428	1678801	-	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase		gene	gene1515	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07580
HSISS4_RS07585	HSISS4_01481		HSISS4_RS07585	1679049	1679639	+	hypothetical protein		gene	gene1516	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07585
HSISS4_RS07590	HSISS4_01482		HSISS4_RS07590	1679608	1680333	+	hypothetical protein		gene	gene1517	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07590
HSISS4_RS07595	HSISS4_01483		HSISS4_RS07595	1680305	1680988	+	hypothetical protein		gene	gene1518	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07595
HSISS4_RS07600	HSISS4_01484		HSISS4_RS07600	1681106	1681960	-	amino acid ABC transporter substrate-binding protein		gene	gene1519	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07600
HSISS4_RS07605	HSISS4_01485		HSISS4_RS07605	1682004	1682762	-	glutamine ABC transporter ATP-binding protein		gene	gene1520	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07605
HSISS4_RS07610	HSISS4_01486		HSISS4_RS07610	1682764	1683441	-	amino acid ABC transporter permease		gene	gene1521	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07610
HSISS4_RS07615	HSISS4_01487		HSISS4_RS07615	1683401	1684081	-	polar amino acid ABC transporter permease		gene	gene1522	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07615
HSISS4_RS07620	HSISS4_01488		HSISS4_RS07620	1684520	1685566	-	D-alanine--D-alanine ligase A		gene	gene1523	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07620
HSISS4_RS07625	HSISS4_01489		HSISS4_RS07625	1685705	1685908	-	copper-binding protein		gene	gene1524	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07625
HSISS4_RS07630	HSISS4_01490		HSISS4_RS07630	1685983	1688211	-	hypothetical protein		gene	gene1525	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07630
HSISS4_RS07635	HSISS4_01491		HSISS4_RS07635	1688214	1688645	-	uracil phosphoribosyltransferase		gene	gene1526	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07635
HSISS4_RS07640	HSISS4_01492		HSISS4_RS07640	1688813	1689985	-	MFS transporter permease		gene	gene1527	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07640
HSISS4_RS07645	HSISS4_01494		HSISS4_RS07645	1690734	1691516	-	tryptophan synthase subunit alpha		gene	gene1528	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07645
HSISS4_RS07650	HSISS4_01495		HSISS4_RS07650	1691520	1692728	-	tryptophan synthase subunit beta	catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate	gene	gene1529	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07650
HSISS4_RS07655	HSISS4_01496		HSISS4_RS07655	1692725	1693306	-	N-(5'-phosphoribosyl)anthranilate isomerase		gene	gene1530	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07655
HSISS4_RS07660	HSISS4_01497		HSISS4_RS07660	1693293	1694060	-	indole-3-glycerol-phosphate synthase		gene	gene1531	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07660
HSISS4_RS07665	HSISS4_01498		HSISS4_RS07665	1694057	1695061	-	anthranilate phosphoribosyltransferase		gene	gene1532	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07665
HSISS4_RS07670	HSISS4_01499		HSISS4_RS07670	1695152	1695718	-	glutamine amidotransferase		gene	gene1533	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07670
HSISS4_RS07675	HSISS4_01500		HSISS4_RS07675	1695715	1697070	-	anthranilate synthase component I	with component II%2C the glutamine amidotransferase%2C catalyzes the formation of anthranilate from chorismate and glutamine	gene	gene1534	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07675
HSISS4_RS07680	HSISS4_01501		HSISS4_RS07680	1697797	1698147	-	hypothetical protein		gene	gene1535	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07680
HSISS4_RS07685	HSISS4_01502		HSISS4_RS07685	1698243	1700591	-	hypothetical protein		gene	gene1536	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07685
HSISS4_RS07690	HSISS4_01503		HSISS4_RS07690	1700755	1701264	-	hypothetical protein		gene	gene1537	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07690
HSISS4_RS07695	HSISS4_01504		HSISS4_RS07695	1701288	1701794	-	hypothetical protein		gene	gene1538	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07695
HSISS4_RS07700	HSISS4_01505		HSISS4_RS07700	1702106	1702405	+	transcriptional regulatory protein		gene	gene1539	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07700
HSISS4_RS07705	HSISS4_01506		HSISS4_RS07705	1702524	1703141	-	signal peptide protein		gene	gene1540	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07705
HSISS4_RS07710	HSISS4_01508		HSISS4_RS07710	1704244	1704945	+	macrolide ABC transporter ATP-binding protein		gene	gene1541	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07710
HSISS4_RS07715	HSISS4_01509		HSISS4_RS07715	1704960	1707602	+	ABC transporter permease		gene	gene1542	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07715
HSISS4_RS07720	HSISS4_01510		HSISS4_RS07720	1707654	1708382	-	MerR family transcriptional regulator		gene	gene1543	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07720
HSISS4_RS07725	HSISS4_01511		HSISS4_RS07725	1708557	1709147	-	DNA polymerase III subunit epsilon	3'-5' exonuclease of DNA polymerase III	gene	gene1544	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07725
HSISS4_RS07730	HSISS4_01512		HSISS4_RS07730	1709196	1709732	-	hypothetical protein		gene	gene1545	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07730
HSISS4_RS07735	HSISS4_01513		HSISS4_RS07735	1710249	1710608	+	cytosolic protein		gene	gene1546	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07735
HSISS4_RS07740	HSISS4_01514		HSISS4_RS07740	1710767	1712470	-	dihydroxy-acid dehydratase	catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis	gene	gene1547	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07740
HSISS4_RS07745	HSISS4_01515		HSISS4_RS07745	1712598	1713779	+	dehydrogenase		gene	gene1548	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07745
HSISS4_RS07750	HSISS4_r00062		HSISS4_RS07750	1713889	1713975	-	tRNA-Ser		tRNA	gene1549	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07750
HSISS4_RS07755	HSISS4_01516		HSISS4_RS07755	1714034	1714675	-	tRNA (guanosine(46)-N7)-methyltransferase TrmB		gene	gene1550	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07755
HSISS4_RS07760	HSISS4_01517		HSISS4_RS07760	1714685	1715476	-	aminoglycoside phosphotransferase		gene	gene1551	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07760
HSISS4_RS07765	HSISS4_01518		HSISS4_RS07765	1715534	1716571	-	ABC transporter permease EscB		gene	gene1552	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07765
HSISS4_RS07770	HSISS4_01519		HSISS4_RS07770	1716568	1717299	-	ABC transporter ATP-binding protein		gene	gene1553	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07770
HSISS4_RS07775	HSISS4_01520		HSISS4_RS07775	1717364	1717783	+	histidine triad protein		gene	gene1554	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07775
HSISS4_RS07780	HSISS4_01521		HSISS4_RS07780	1717780	1718079	+	hypothetical protein		gene	gene1555	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07780
HSISS4_RS07785	HSISS4_01522		HSISS4_RS07785	1718111	1718887	-	hypothetical protein		gene	gene1556	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07785
HSISS4_RS07790	HSISS4_01523		HSISS4_RS07790	1719321	1721426	-	ATP-dependent Clpproteinase(ATP-binding subunit)		gene	gene1557	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07790
HSISS4_RS07795	HSISS4_01524		HSISS4_RS07795	1722127	1722381	-	YoeB toxin protein		gene	gene1558	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07795
HSISS4_RS07800	HSISS4_01525		HSISS4_RS07800	1722385	1722639	-	prevent-host-death protein		gene	gene1559	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07800
HSISS4_RS07805	HSISS4_01526		HSISS4_RS07805	1722781	1723872	-	hypothetical protein		gene	gene1560	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07805
HSISS4_RS07810	HSISS4_01527		HSISS4_RS07810	1723879	1724619	-	methyltransferase		gene	gene1561	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07810
HSISS4_RS07815	HSISS4_01528		HSISS4_RS07815	1724824	1725177	-	ribosome silencing factor RsfS		gene	gene1562	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07815
HSISS4_RS07820	HSISS4_01529		HSISS4_RS07820	1725200	1725790	-	haloacid dehalogenase		gene	gene1563	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07820
HSISS4_RS07825	HSISS4_01530	nadD	nadD	1725787	1726419	-	nicotinate-nicotinamide nucleotide adenylyltransferase	transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase%3B essential enzyme in bacteria	gene	gene1564	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07825
HSISS4_RS07830	HSISS4_01531		HSISS4_RS07830	1726525	1726842	-	RNA-binding protein		gene	gene1565	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07830
HSISS4_RS07835	HSISS4_01532		HSISS4_RS07835	1727268	1728386	-	ribosome biogenesis GTPase YqeH	in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis	gene	gene1566	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07835
HSISS4_RS07840	HSISS4_01533		HSISS4_RS07840	1728386	1728913	-	haloacid dehalogenase		gene	gene1567	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07840
HSISS4_RS07845	HSISS4_01534		HSISS4_RS07845	1729051	1729968	-	multidrug DMT transporter permease		gene	gene1568	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07845
HSISS4_RS07850	HSISS4_01535		HSISS4_RS07850	1730066	1731109	-	butanediol dehydrogenase		gene	gene1569	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07850
HSISS4_RS07855	HSISS4_01537		HSISS4_RS07855	1731269	1731652	-	hypothetical protein		gene	gene1570	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07855
HSISS4_RS07860	HSISS4_01538		HSISS4_RS07860	1731781	1733043	-	hypothetical protein		gene	gene1571	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07860
HSISS4_RS07865	HSISS4_01539		HSISS4_RS07865	1733136	1734578	-	aspartyl/glutamyl-tRNA amidotransferase subunit B		gene	gene1572	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07865
HSISS4_RS07870	HSISS4_01540	gatA	gatA	1734578	1736044	-	aspartyl/glutamyl-tRNA amidotransferase subunit A	allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases%3B reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA	gene	gene1573	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07870
HSISS4_RS07875	HSISS4_01541		HSISS4_RS07875	1736044	1736346	-	aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C		gene	gene1574	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07875
HSISS4_RS07880	HSISS4_01542		HSISS4_RS07880	1736486	1737958	-	poly(glycerol-phosphate)alpha-glucosyltransferase GftA		gene	gene1575	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07880
HSISS4_RS07885	HSISS4_01543		HSISS4_RS07885	1737939	1739237	-	GftB--glycosyl transferase		gene	gene1576	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07885
HSISS4_RS07890	HSISS4_01544		HSISS4_RS07890	1739287	1740168	-	hypothetical protein		gene	gene1577	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07890
HSISS4_RS07895	HSISS4_01545		HSISS4_RS07895	1740172	1741380	-	glycosyl transferase		gene	gene1578	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07895
HSISS4_RS07900	HSISS4_01546		HSISS4_RS07900	1741575	1743014	-	6-phospho-beta-glucosidase		gene	gene1579	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07900
HSISS4_RS07905	HSISS4_01547		HSISS4_RS07905	1743170	1743721	-	nicotinamidase		gene	gene1580	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07905
HSISS4_RS07910	HSISS4_01548		HSISS4_RS07910	1743788	1744573	-	transcriptional regulator	CodY%3B DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	gene	gene1581	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07910
HSISS4_RS07915	HSISS4_01549		HSISS4_RS07915	1744841	1746055	-	aminotransferase AlaT	broad specificity%3B family IV%3B in Corynebacterium glutamicum this protein can use glutamate%2C 2-aminobutyrate%2C and aspartate as amino donors and pyruvate as the acceptor	gene	gene1582	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07915
HSISS4_RS07920	HSISS4_01550		HSISS4_RS07920	1746415	1746867	+	universal stress protein UspA		gene	gene1583	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07920
HSISS4_RS07925	HSISS4_01551		HSISS4_RS07925	1746947	1747699	-	membrane protein		gene	gene1584	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07925
HSISS4_RS07930	HSISS4_01552	pflA	pflA	1747769	1748569	-	pyruvate formate-lyase activating enzyme	activates pyruvate formate-lyase 1 under anaerobic conditions	gene	gene1585	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07930
HSISS4_RS07935	HSISS4_01553		HSISS4_RS07935	1748756	1749496	-	hypothetical protein		gene	gene1586	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07935
HSISS4_RS07940	HSISS4_01554		HSISS4_RS07940	1749851	1751182	-	hemolysin		gene	gene1587	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07940
HSISS4_RS07945	HSISS4_01555		HSISS4_RS07945	1751294	1752076	+	molybdenum ABC transporter ATP-binding protein		gene	gene1588	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07945
HSISS4_RS07950	HSISS4_01556		HSISS4_RS07950	1752164	1753420	-	transposase		gene	gene1589	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07950
HSISS4_RS07955	HSISS4_01557		HSISS4_RS07955	1753680	1755746	-	Na+/H+ antiporter		gene	gene1590	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07955
HSISS4_RS07960	HSISS4_01558		HSISS4_RS07960	1755755	1755997	-	hypothetical protein		gene	gene1591	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07960
HSISS4_RS07965	HSISS4_01559		HSISS4_RS07965	1755994	1756542	-	SAM-dependent methyltransferase		gene	gene1592	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07965
HSISS4_RS07970	HSISS4_01560		HSISS4_RS07970	1756539	1757483	-	radical SAM protein		gene	gene1593	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07970
HSISS4_RS07975	HSISS4_01561		HSISS4_RS07975	1757569	1758645	-	Lon-like protease		gene	gene1594	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07975
HSISS4_RS07980	HSISS4_01562		HSISS4_RS07980	1758623	1759120	-	phosphopantetheine adenylyltransferase		gene	gene1595	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07980
HSISS4_RS07985	HSISS4_01563		HSISS4_RS07985	1759153	1759692	-	ribosomal RNA small subunit methyltransferase		gene	gene1596	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07985
HSISS4_RS07990	HSISS4_01564		HSISS4_RS07990	1759843	1760763	-	thioredoxin reductase		gene	gene1597	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07990
HSISS4_RS07995	HSISS4_01565		HSISS4_RS07995	1760829	1761053	-	thioredoxin		gene	gene1598	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS07995
HSISS4_RS08000	HSISS4_01566		HSISS4_RS08000	1761265	1762008	-	amino acid ABC transporter ATP-binding protein		gene	gene1599	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08000
HSISS4_RS08005	HSISS4_01567		HSISS4_RS08005	1762008	1762931	-	amino acid ABC transporter permease		gene	gene1600	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08005
HSISS4_RS08010	HSISS4_01568		HSISS4_RS08010	1763209	1764039	-	hypothetical protein		gene	gene1601	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08010
HSISS4_RS08015	HSISS4_01569		HSISS4_RS08015	1764255	1765145	-	hypothetical protein		gene	gene1602	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08015
HSISS4_RS08020	HSISS4_01570		HSISS4_RS08020	1765262	1766368	-	DNA polymerase IV		gene	gene1603	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08020
HSISS4_RS08025	HSISS4_01571		HSISS4_RS08025	1766636	1768948	+	pyruvate formate-lyase		gene	gene1604	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08025
HSISS4_RS08030	HSISS4_01572		HSISS4_RS08030	1769211	1769996	+	carbonic anhydrase		gene	gene1605	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08030
HSISS4_RS08035	HSISS4_01573		HSISS4_RS08035	1770082	1770534	+	GNAT family acetyltransferase		gene	gene1606	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08035
HSISS4_RS08040	HSISS4_01574		HSISS4_RS08040	1770551	1771213	-	hypothetical protein		gene	gene1607	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08040
HSISS4_RS08045	HSISS4_01575		HSISS4_RS08045	1771301	1771846	-	hypothetical protein		gene	gene1608	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08045
HSISS4_RS08050	HSISS4_01576		HSISS4_RS08050	1771908	1772852	-	serine hydrolase		gene	gene1609	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08050
HSISS4_RS08055	HSISS4_01577		HSISS4_RS08055	1772852	1773607	-	hypothetical protein		gene	gene1610	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08055
HSISS4_RS08060	HSISS4_01578		HSISS4_RS08060	1773781	1774452	+	protease		gene	gene1611	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08060
HSISS4_RS08065	HSISS4_01579		HSISS4_RS08065	1774540	1775406	-	aquaporin		gene	gene1612	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08065
HSISS4_RS08070	HSISS4_01580		HSISS4_RS08070	1775530	1777797	+	naa-Pro dipeptidyl-peptidase	catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue	gene	gene1613	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08070
HSISS4_RS08075	HSISS4_01581		HSISS4_RS08075	1777995	1778291	-	Mundticin KS immunity protein		gene	gene1614	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08075
HSISS4_RS08080	HSISS4_01582		HSISS4_RS08080	1778330	1778536	-	hypothetical protein		gene	gene1615	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08080
HSISS4_RS08085	HSISS4_01586		HSISS4_RS08085	1780315	1780545	-	bacteriocin BlpU		gene	gene1616	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08085
HSISS4_RS08090	HSISS4_01587		HSISS4_RS08090	1780705	1782450	-	multidrug ABC transporter ATP-binding protein		gene	gene1617	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08090
HSISS4_RS08095	HSISS4_01588		HSISS4_RS08095	1782443	1784200	-	ABC transporter ATP-binding/permease		gene	gene1618	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08095
HSISS4_RS08100	HSISS4_01589		HSISS4_RS08100	1784249	1784644	-	hypothetical protein		gene	gene1619	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08100
HSISS4_RS08105	HSISS4_01590		HSISS4_RS08105	1784798	1785325	-	VanZF-related protein		gene	gene1620	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08105
HSISS4_RS08110	HSISS4_01591		HSISS4_RS08110	1785327	1786496	-	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	23S rRNA m2A2503 methyltransferase%3B methylates the C2 position of the A2530 nucleotide in 23S rRNA%3B may be involved in antibiotic resistance	gene	gene1621	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08110
HSISS4_RS08115	HSISS4_01592		HSISS4_RS08115	1786500	1787228	-	transcriptional regulator		gene	gene1622	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08115
HSISS4_RS08120	HSISS4_01593		HSISS4_RS08120	1787283	1788638	-	5'-nucleotidase		gene	gene1623	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08120
HSISS4_RS08125	HSISS4_RS08125		HSISS4_RS08125	1788728	1788934	-	hypothetical protein		gene	gene1624	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08125
HSISS4_RS08130	HSISS4_01594		HSISS4_RS08130	1788912	1789142	-	hypothetical protein		gene	gene1625	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08130
HSISS4_RS08135	HSISS4_01595		HSISS4_RS08135	1789622	1790965	-	DEAD/DEAH box helicase		gene	gene1626	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08135
HSISS4_RS08140	HSISS4_01596		HSISS4_RS08140	1791039	1792061	-	phospho-N-acetylmuramoyl-pentapeptide-transferase		gene	gene1627	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08140
HSISS4_RS08145	HSISS4_01597		HSISS4_RS08145	1792063	1794330	-	penicillin-binding protein		gene	gene1628	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08145
HSISS4_RS08150	HSISS4_01598		HSISS4_RS08150	1794334	1794654	-	cell division protein FtsL		gene	gene1629	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08150
HSISS4_RS08155	HSISS4_01599		HSISS4_RS08155	1794657	1795607	-	ribosomal RNA small subunit methyltransferase H	catalyzes the methylation of the N4 position of C1402 on the 16S rRNA	gene	gene1630	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08155
HSISS4_RS08160	HSISS4_01600		HSISS4_RS08160	1795718	1796746	-	hypothetical protein		gene	gene1631	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08160
HSISS4_RS08165	HSISS4_01601		HSISS4_RS08165	1796777	1797238	-	hypothetical protein		gene	gene1632	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08165
HSISS4_RS08170	HSISS4_01602		HSISS4_RS08170	1797380	1797778	-	hypothetical protein		gene	gene1633	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08170
HSISS4_RS08175	HSISS4_01603		HSISS4_RS08175	1797877	1798275	-	hypothetical protein		gene	gene1634	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08175
HSISS4_RS08180	HSISS4_01604		HSISS4_RS08180	1798389	1798781	-	membrane protein		gene	gene1635	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08180
HSISS4_RS08185	HSISS4_01605		HSISS4_RS08185	1798876	1800126	-	gamma-glutamyl-phosphate reductase		gene	gene1636	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08185
HSISS4_RS08190	HSISS4_01606		HSISS4_RS08190	1800128	1800931	-	gamma-glutamyl kinase	catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis	gene	gene1637	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08190
HSISS4_RS08195	HSISS4_01607		HSISS4_RS08195	1801051	1802640	-	ABC transporter permease		gene	gene1638	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08195
HSISS4_RS08200	HSISS4_01608		HSISS4_RS08200	1802643	1803374	-	ABC transporter ATP-binding protein		gene	gene1639	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08200
HSISS4_RS08205	HSISS4_01609		HSISS4_RS08205	1803650	1804381	+	hypothetical protein		gene	gene1640	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08205
HSISS4_RS08210	HSISS4_01610		HSISS4_RS08210	1804734	1808387	-	ATP-dependent nuclease subunit A		gene	gene1641	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08210
HSISS4_RS08215	HSISS4_01611		HSISS4_RS08215	1808377	1811697	-	ATP-dependent nuclease subunit B		gene	gene1642	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08215
HSISS4_RS08220	HSISS4_01612		HSISS4_RS08220	1811947	1813320	-	GHKL domain-containing protein		gene	gene1643	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08220
HSISS4_RS08225	HSISS4_01613		HSISS4_RS08225	1813355	1814665	-	Sensory transduction protein kinase		gene	gene1644	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08225
HSISS4_RS08230	HSISS4_01614		HSISS4_RS08230	1814945	1816684	-	hypothetical protein		gene	gene1645	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08230
HSISS4_RS08235	HSISS4_01615		HSISS4_RS08235	1816694	1816954	-	ABC transporter		gene	gene1646	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08235
HSISS4_RS08240	HSISS4_01616		HSISS4_RS08240	1816955	1817770	-	serine/threonine protein kinase		gene	gene1647	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08240
HSISS4_RS08245	HSISS4_01617		HSISS4_RS08245	1817779	1818564	-	hypothetical protein		gene	gene1648	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08245
HSISS4_RS08250	HSISS4_01618		HSISS4_RS08250	1818574	1819086	-	hypothetical protein		gene	gene1649	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08250
HSISS4_RS08255	HSISS4_01619		HSISS4_RS08255	1819083	1820681	-	chaperone protein DnaK		gene	gene1650	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08255
HSISS4_RS08260	HSISS4_01620		HSISS4_RS08260	1821008	1821703	-	hypothetical protein		gene	gene1651	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08260
HSISS4_RS08265	HSISS4_01621		HSISS4_RS08265	1821708	1822154	-	transcriptional regulator		gene	gene1652	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08265
HSISS4_RS08270	HSISS4_01622		HSISS4_RS08270	1822365	1824092	-	hypothetical protein		gene	gene1653	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08270
HSISS4_RS08275	HSISS4_01623		HSISS4_RS08275	1824139	1825320	-	hypothetical protein		gene	gene1654	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08275
HSISS4_RS08280	HSISS4_01624		HSISS4_RS08280	1825438	1826823	-	haloacid dehalogenase		gene	gene1655	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08280
HSISS4_RS08285	HSISS4_01625		HSISS4_RS08285	1826895	1827863	+	L-asparaginase		gene	gene1656	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08285
HSISS4_RS08290	HSISS4_01627		HSISS4_RS08290	1828061	1828273	-	transcriptional regulator		gene	gene1657	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08290
HSISS4_RS08295	HSISS4_01628		HSISS4_RS08295	1828283	1828891	-	hypothetical protein		gene	gene1658	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08295
HSISS4_RS08300	HSISS4_01629		HSISS4_RS08300	1829084	1829521	-	hypothetical protein		gene	gene1659	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08300
HSISS4_RS08305	HSISS4_01631		HSISS4_RS08305	1830139	1830645	-	hypothetical protein		gene	gene1660	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08305
HSISS4_RS08310	HSISS4_01632		HSISS4_RS08310	1830657	1832675	-	ATP-dependent DNA helicase RecG		gene	gene1661	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08310
HSISS4_RS08315	HSISS4_01633		HSISS4_RS08315	1832806	1833909	-	alanine racemase		gene	gene1662	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08315
HSISS4_RS08320	HSISS4_01634		HSISS4_RS08320	1833937	1834290	-	4'-phosphopantetheinyl transferase		gene	gene1663	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08320
HSISS4_RS08325	HSISS4_01635		HSISS4_RS08325	1834296	1835324	-	2-keto-3-deoxy-D-arabino-heptulosonate-7-phosphate synthase I alpha		gene	gene1664	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08325
HSISS4_RS08330	HSISS4_01636		HSISS4_RS08330	1835409	1836440	-	phospho-2-dehydro-3-deoxyheptonate aldolase		gene	gene1665	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08330
HSISS4_RS08335	HSISS4_01637		HSISS4_RS08335	1836461	1839010	-	preprotein translocase subunit SecA		gene	gene1666	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08335
HSISS4_RS08340	HSISS4_01638		HSISS4_RS08340	1839194	1839454	-	hypothetical protein		gene	gene1667	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08340
HSISS4_RS08345	HSISS4_01639		HSISS4_RS08345	1839541	1840488	-	mannose-6-phosphate isomerase		gene	gene1668	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08345
HSISS4_RS08350	HSISS4_01640		HSISS4_RS08350	1840554	1841447	-	fructokinase		gene	gene1669	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08350
HSISS4_RS08355	HSISS4_01641		HSISS4_RS08355	1841628	1843529	-	PTS beta-glucoside transporter subunit EIIBCA		gene	gene1670	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08355
HSISS4_RS08360	HSISS4_01642		HSISS4_RS08360	1843718	1845160	+	sucrose-6-phosphate hydrolase		gene	gene1671	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08360
HSISS4_RS08365	HSISS4_01643		HSISS4_RS08365	1845169	1846134	+	LacI family transcriptional regulator		gene	gene1672	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08365
HSISS4_RS08370	HSISS4_01644		HSISS4_RS08370	1846225	1846659	-	N utilization substance protein B		gene	gene1673	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08370
HSISS4_RS08375	HSISS4_01645		HSISS4_RS08375	1846652	1847041	-	hypothetical protein		gene	gene1674	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08375
HSISS4_RS08380	HSISS4_01646		HSISS4_RS08380	1847112	1847672	-	elongation factor P	Involved in peptide bond synthesis%3B alters the affinity of the ribosome for aminoacyl-tRNA	gene	gene1675	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08380
HSISS4_RS08385	HSISS4_01647		HSISS4_RS08385	1847787	1848242	-	dCMP deaminase Late competence protein ComEB		gene	gene1676	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08385
HSISS4_RS08390	HSISS4_01648		HSISS4_RS08390	1848261	1849322	-	Aminopeptidase YpdF (MP-%2C MA-%2C MS-%2C AP-%2CNP-specific)		gene	gene1677	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08390
HSISS4_RS08395	HSISS4_01649		HSISS4_RS08395	1849455	1849940	-	membrane protein		gene	gene1678	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08395
HSISS4_RS08400	HSISS4_01650		HSISS4_RS08400	1850167	1850988	-	peptide ABC transporter ATP-binding protein		gene	gene1679	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08400
HSISS4_RS08405	HSISS4_01651		HSISS4_RS08405	1851117	1851977	-	thiol reductase thioredoxin		gene	gene1680	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08405
HSISS4_RS08410	HSISS4_01652		HSISS4_RS08410	1852243	1852443	-	hypothetical protein		gene	gene1681	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08410
HSISS4_RS08415	HSISS4_01654		HSISS4_RS08415	1852804	1853046	-	membrane protein		gene	gene1682	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08415
HSISS4_RS08420	HSISS4_01655		HSISS4_RS08420	1853140	1855965	-	ABC-ATPase UvrA		gene	gene1683	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08420
HSISS4_RS08425	HSISS4_01656		HSISS4_RS08425	1856262	1857206	+	magnesium and cobalt transporter CorA		gene	gene1684	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08425
HSISS4_RS08430	HSISS4_01657		HSISS4_RS08430	1857276	1857947	+	membrane protein		gene	gene1685	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08430
HSISS4_RS08435	HSISS4_01658		HSISS4_RS08435	1858064	1858945	+	hypothetical protein		gene	gene1686	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08435
HSISS4_RS08440	HSISS4_01659		HSISS4_RS08440	1859068	1859307	-	30S ribosomal protein S18		gene	gene1687	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08440
HSISS4_RS08445	HSISS4_01660		HSISS4_RS08445	1859349	1859867	-	single-stranded DNA-binding protein	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA	gene	gene1688	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08445
HSISS4_RS08450	HSISS4_01661		HSISS4_RS08450	1859879	1860169	-	30S ribosomal protein S6		gene	gene1689	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08450
HSISS4_RS08455	HSISS4_01662		HSISS4_RS08455	1860373	1861326	+	hypothetical protein		gene	gene1690	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08455
HSISS4_RS08460	HSISS4_RS08460		HSISS4_RS08460	1862275	1862463	-	hypothetical protein		gene	gene1691	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08460
HSISS4_RS08465	HSISS4_01663		HSISS4_RS08465	1862502	1863653	+	A/G-specific adenine glycosylase		gene	gene1692	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08465
HSISS4_RS08470	HSISS4_01665		HSISS4_RS08470	1863797	1863982	-	hypothetical protein		gene	gene1693	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08470
HSISS4_RS08475	HSISS4_01666		HSISS4_RS08475	1864267	1865364	-	hypothetical protein		gene	gene1694	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08475
HSISS4_RS08480	HSISS4_01668		HSISS4_RS08480	1865781	1868420	-	DNA polymerase I		gene	gene1695	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08480
HSISS4_RS08485	HSISS4_01669		HSISS4_RS08485	1868654	1871002	+	Recombination inhibitory protein MutS2		gene	gene1696	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08485
HSISS4_RS08490	HSISS4_01670		HSISS4_RS08490	1871104	1871646	-	colicin V production protein		gene	gene1697	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08490
HSISS4_RS08495	HSISS4_01671		HSISS4_RS08495	1871643	1871957	-	hypothetical protein		gene	gene1698	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08495
HSISS4_RS08500	HSISS4_01672		HSISS4_RS08500	1872274	1873164	+	ribonuclease HIII		gene	gene1699	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08500
HSISS4_RS08505	HSISS4_01673		HSISS4_RS08505	1873183	1873824	+	S26 family signal peptidase		gene	gene1700	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08505
HSISS4_RS08510	HSISS4_01674		HSISS4_RS08510	1873885	1876389	+	RecD-like DNA helicase YrrC		gene	gene1701	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08510
HSISS4_RS08515	HSISS4_01675		HSISS4_RS08515	1876441	1876767	-	branched-chain amino acid transporter		gene	gene1702	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08515
HSISS4_RS08520	HSISS4_01676		HSISS4_RS08520	1876754	1877446	-	branched-chain amino acid ABC transporter permease		gene	gene1703	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08520
HSISS4_RS08525	HSISS4_01677		HSISS4_RS08525	1877498	1878511	-	N(6)-L-threonylcarbamoyladenine synthase TsaD		gene	gene1704	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08525
HSISS4_RS08530	HSISS4_01678		HSISS4_RS08530	1878511	1878966	-	ribosomal-protein-alanine N-acetyltransferase RimI		gene	gene1705	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08530
HSISS4_RS08535	HSISS4_01679		HSISS4_RS08535	1878926	1879612	-	tRNA threonylcarbamoyladenosine biosynthesis protein TsaB		gene	gene1706	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08535
HSISS4_RS08540	HSISS4_01680		HSISS4_RS08540	1879873	1880103	+	hypothetical protein		gene	gene1707	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08540
HSISS4_RS08545	HSISS4_01681		HSISS4_RS08545	1880108	1881790	+	ribonuclease J		gene	gene1708	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08545
HSISS4_RS08550	HSISS4_01682		HSISS4_RS08550	1881891	1882523	-	hypothetical protein		gene	gene1709	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08550
HSISS4_RS08555	HSISS4_01683		HSISS4_RS08555	1882710	1884053	-	glutamine synthetase		gene	gene1710	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08555
HSISS4_RS08560	HSISS4_01684		HSISS4_RS08560	1884102	1884476	-	MerR family transcriptional regulator		gene	gene1711	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08560
HSISS4_RS08565	HSISS4_01685		HSISS4_RS08565	1884650	1885153	-	membrane protein		gene	gene1712	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08565
HSISS4_RS08570	HSISS4_01686		HSISS4_RS08570	1885341	1886540	-	phosphoglycerate kinase		gene	gene1713	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08570
HSISS4_RS08575	HSISS4_01687		HSISS4_RS08575	1886682	1887386	+	hypothetical protein		gene	gene1714	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08575
HSISS4_RS08580	HSISS4_01688		HSISS4_RS08580	1887498	1888508	-	glyceraldehyde-3-phosphate dehydrogenase	NAD-dependent%3B catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate%3B active during glycolysis	gene	gene1715	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08580
HSISS4_RS08585	HSISS4_01689	fusA	fusA	1888696	1890777	-	elongation factor G	EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene	gene	gene1716	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08585
HSISS4_RS08590	HSISS4_01690		HSISS4_RS08590	1890990	1891460	-	30S ribosomal protein S7		gene	gene1717	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08590
HSISS4_RS08595	HSISS4_01691		HSISS4_RS08595	1891479	1891892	-	30S ribosomal protein S12		gene	gene1718	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08595
HSISS4_RS08600	HSISS4_01692		HSISS4_RS08600	1892121	1892936	-	pur operon repressor		gene	gene1719	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08600
HSISS4_RS08605	HSISS4_01693		HSISS4_RS08605	1893030	1893971	-	3'-5' exoribonuclease	catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates	gene	gene1720	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08605
HSISS4_RS08610	HSISS4_01694		HSISS4_RS08610	1893961	1895235	-	DNA recombination protein RmuC		gene	gene1721	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08610
HSISS4_RS08615	HSISS4_01695		HSISS4_RS08615	1895237	1895869	-	thiamin pyrophosphokinase		gene	gene1722	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08615
HSISS4_RS08620	HSISS4_01696		HSISS4_RS08620	1895862	1896521	-	ribulose-phosphate 3-epimerase	catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate	gene	gene1723	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08620
HSISS4_RS08625	HSISS4_01697		HSISS4_RS08625	1896529	1897401	-	ribosome small subunit-stimulated GTPase EngC		gene	gene1724	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08625
HSISS4_RS08630	HSISS4_r00063		HSISS4_RS08630	1897538	1897620	+	tRNA-Leu		tRNA	gene1725	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08630
HSISS4_RS08635	HSISS4_01698		HSISS4_RS08635	1897660	1898532	-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase		gene	gene1726	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08635
HSISS4_RS08640	HSISS4_01699		HSISS4_RS08640	1898659	1899219	-	ribonuclease M5		gene	gene1727	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08640
HSISS4_RS08645	HSISS4_01700		HSISS4_RS08645	1899212	1899988	-	hydrolase TatD		gene	gene1728	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08645
HSISS4_RS08650	HSISS4_01701		HSISS4_RS08650	1900042	1900473	-	succinyl-CoA synthetase subunit alpha-related enzyme		gene	gene1729	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08650
HSISS4_RS08655	HSISS4_01702		HSISS4_RS08655	1900539	1900853	-	thiol reductase thioredoxin		gene	gene1730	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08655
HSISS4_RS08660	HSISS4_01703		HSISS4_RS08660	1901049	1901831	+	Macro domain%2C possibly ADP-ribose-binding module		gene	gene1731	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08660
HSISS4_RS08665	HSISS4_01704		HSISS4_RS08665	1901867	1902280	-	esterase		gene	gene1732	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08665
HSISS4_RS08670	HSISS4_01705		HSISS4_RS08670	1902298	1902633	-	thiol reductase thioredoxin		gene	gene1733	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08670
HSISS4_RS08675	HSISS4_r00064		HSISS4_RS08675	1902745	1902818	-	tRNA-Asn		tRNA	gene1734	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08675
HSISS4_RS08680	HSISS4_r00065	rrf	rrf	1902824	1902939	-	5S ribosomal RNA		rRNA	gene1735	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08680
HSISS4_RS08685	HSISS4_r00066		HSISS4_RS08685	1903022	1905923	-	23S ribosomal RNA		rRNA	gene1736	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08685
HSISS4_RS08690	HSISS4_r00067		HSISS4_RS08690	1906069	1906141	-	tRNA-Ala		tRNA	gene1737	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08690
HSISS4_RS08695	HSISS4_r00068		HSISS4_RS08695	1906188	1907742	-	16S ribosomal RNA		rRNA	gene1738	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08695
HSISS4_RS08700	HSISS4_r00069		HSISS4_RS08700	1907873	1907946	-	tRNA-Pro		tRNA	gene1739	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08700
HSISS4_RS08705	HSISS4_r00070		HSISS4_RS08705	1907953	1908026	-	tRNA-Arg		tRNA	gene1740	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08705
HSISS4_RS08710	HSISS4_r00071		HSISS4_RS08710	1908041	1908126	-	tRNA-Leu		tRNA	gene1741	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08710
HSISS4_RS08715	HSISS4_r00072		HSISS4_RS08715	1908133	1908204	-	tRNA-Gly		tRNA	gene1742	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08715
HSISS4_RS08720	HSISS4_r00073		HSISS4_RS08720	1908211	1908283	-	tRNA-Thr		tRNA	gene1743	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08720
HSISS4_RS08725	HSISS4_r00074		HSISS4_RS08725	1908296	1908377	-	tRNA-Leu		tRNA	gene1744	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08725
HSISS4_RS08730	HSISS4_r00075		HSISS4_RS08730	1908383	1908455	-	tRNA-Lys		tRNA	gene1745	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08730
HSISS4_RS08735	HSISS4_r00076		HSISS4_RS08735	1908471	1908546	-	tRNA-Asp		tRNA	gene1746	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08735
HSISS4_RS08740	HSISS4_r00077		HSISS4_RS08740	1908549	1908621	-	tRNA-Val		tRNA	gene1747	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08740
HSISS4_RS08745	HSISS4_r00078	rrf	rrf	1908627	1908742	-	5S ribosomal RNA		rRNA	gene1748	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08745
HSISS4_RS08750	HSISS4_r00079		HSISS4_RS08750	1908825	1911726	-	23S ribosomal RNA		rRNA	gene1749	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08750
HSISS4_RS08755	HSISS4_r00080		HSISS4_RS08755	1911872	1911944	-	tRNA-Ala		tRNA	gene1750	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08755
HSISS4_RS08760	HSISS4_r00081		HSISS4_RS08760	1911991	1913545	-	16S ribosomal RNA		rRNA	gene1751	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08760
HSISS4_RS08765	HSISS4_01706	tgt	tgt	1913961	1915103	-	tRNA guanosine(34) transglycosylase Tgt	Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr)	gene	gene1752	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08765
HSISS4_RS08770	HSISS4_01707		HSISS4_RS08770	1915309	1915443	-	50S ribosomal protein L34		gene	gene1753	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08770
HSISS4_RS08775	HSISS4_01708		HSISS4_RS08775	1915639	1916202	-	hypothetical protein		gene	gene1754	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08775
HSISS4_RS08780	HSISS4_01709		HSISS4_RS08780	1916199	1916795	-	TetR family transcriptional regulator		gene	gene1755	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08780
HSISS4_RS08785	HSISS4_01710		HSISS4_RS08785	1916927	1917970	-	RNA-binding protein Jag		gene	gene1756	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08785
HSISS4_RS08790	HSISS4_01711		HSISS4_RS08790	1917982	1918788	-	membrane protein		gene	gene1757	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08790
HSISS4_RS08795	HSISS4_01712	rnpA	rnpA	1918904	1919239	-	ribonuclease P protein component	protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates	gene	gene1758	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08795
HSISS4_RS08800	HSISS4_01713		HSISS4_RS08800	1919324	1920709	-	argininosuccinate lyase		gene	gene1759	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08800
HSISS4_RS08805	HSISS4_01714		HSISS4_RS08805	1921036	1922235	-	argininosuccinate synthase	catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis%2C AMP-forming	gene	gene1760	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08805
HSISS4_RS08810	HSISS4_01715		HSISS4_RS08810	1923180	1923923	-	DNA-binding response regulator		gene	gene1761	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08810
HSISS4_RS08815	HSISS4_01716		HSISS4_RS08815	1923925	1925241	-	histidine kinase		gene	gene1762	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08815
HSISS4_RS08820	HSISS4_01717		HSISS4_RS08820	1925265	1926545	-	histidine kinase		gene	gene1763	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08820
HSISS4_RS08825	HSISS4_01718		HSISS4_RS08825	1926567	1927457	-	histidine kinase		gene	gene1764	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08825
HSISS4_RS08830	HSISS4_01719		HSISS4_RS08830	1927517	1928824	-	histidine kinase		gene	gene1765	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08830
HSISS4_RS08835	HSISS4_01720		HSISS4_RS08835	1929279	1930733	-	glutamate--tRNA ligase		gene	gene1766	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08835
HSISS4_RS08840	HSISS4_01721		HSISS4_RS08840	1930970	1932940	-	peptide ABC transporter substrate-binding protein		gene	gene1767	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08840
HSISS4_RS08845	HSISS4_01722		HSISS4_RS08845	1933120	1933809	-	50S ribosomal protein L1		gene	gene1768	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08845
HSISS4_RS08850	HSISS4_01723		HSISS4_RS08850	1933909	1934334	-	50S ribosomal protein L11		gene	gene1769	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08850
HSISS4_RS08855	HSISS4_01724		HSISS4_RS08855	1934506	1934859	+	membrane protein		gene	gene1770	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08855
HSISS4_RS08860	HSISS4_01725		HSISS4_RS08860	1934955	1935452	-	carbonic anhydrase		gene	gene1771	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08860
HSISS4_RS08865	HSISS4_01726		HSISS4_RS08865	1935603	1936298	-	TIGR00266 family protein		gene	gene1772	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08865
HSISS4_RS08870	HSISS4_01727		HSISS4_RS08870	1936385	1937632	-	DNA repair protein RadA		gene	gene1773	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08870
HSISS4_RS08875	HSISS4_01728		HSISS4_RS08875	1937743	1938210	-	hypothetical protein		gene	gene1774	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08875
HSISS4_RS08880	HSISS4_01729		HSISS4_RS08880	1938221	1938667	-	deoxyuridine 5'-triphosphate nucleotidohydrolase	catalyzes the formation of dUMP from dUTP	gene	gene1775	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08880
HSISS4_RS08885	HSISS4_01730		HSISS4_RS08885	1938875	1939477	+	fumarate reductase flavoprotein subunit		gene	gene1776	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08885
HSISS4_RS08890	HSISS4_01731		HSISS4_RS08890	1939496	1940743	+	fumarate reductase flavoprotein subunit		gene	gene1777	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08890
HSISS4_RS08895	HSISS4_01732		HSISS4_RS08895	1940861	1941652	+	formate/nitrite transporter		gene	gene1778	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08895
HSISS4_RS08900	HSISS4_01733		HSISS4_RS08900	1941661	1942221	+	membrane protein		gene	gene1779	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08900
HSISS4_RS08905	HSISS4_01734		HSISS4_RS08905	1942340	1943362	+	glycerol-3-phosphate dehydrogenase		gene	gene1780	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08905
HSISS4_RS08910	HSISS4_01735		HSISS4_RS08910	1943380	1944294	+	UTP--glucose-1-phosphate uridylyltransferase		gene	gene1781	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08910
HSISS4_RS08915	HSISS4_01736		HSISS4_RS08915	1944340	1945014	-	rhomboid family intramembrane serine protease		gene	gene1782	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08915
HSISS4_RS08920	HSISS4_01737		HSISS4_RS08920	1945005	1945532	-	5-formyltetrahydrofolate cyclo-ligase		gene	gene1783	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08920
HSISS4_RS08925	HSISS4_01738		HSISS4_RS08925	1945601	1946734	-	N-acetyl-L%2CL-diaminopimelate deacetylase		gene	gene1784	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08925
HSISS4_RS08930	HSISS4_01739		HSISS4_RS08930	1946809	1947507	-	2%2C3%2C4%2C5-tetrahydropyridine-2%2C6-dicarboxylate N-acetyltransferase		gene	gene1785	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08930
HSISS4_RS08935	HSISS4_01740		HSISS4_RS08935	1947593	1948345	-	hypothetical protein		gene	gene1786	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08935
HSISS4_RS08940	HSISS4_01741		HSISS4_RS08940	1948462	1949295	-	ribosomal RNA large subunit methyltransferase		gene	gene1787	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08940
HSISS4_RS08945	HSISS4_RS08945	ffs	ffs	1949310	1949395	-	signal recognition particle sRNA small type		ncRNA	gene1788	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08945
HSISS4_RS08950	HSISS4_01742		HSISS4_RS08950	1949716	1949874	+	hypothetical protein		gene	gene1789	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08950
HSISS4_RS08955	HSISS4_01743		HSISS4_RS08955	1949894	1950061	+	bacteriocin		gene	gene1790	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08955
HSISS4_RS08960	HSISS4_01744		HSISS4_RS08960	1950109	1950363	+	hypothetical protein		gene	gene1791	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08960
HSISS4_RS08965	HSISS4_01745		HSISS4_RS08965	1950448	1950966	-	tRNA-specific adenosine deaminase		gene	gene1792	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08965
HSISS4_RS08970	HSISS4_01746		HSISS4_RS08970	1951736	1952128	-	single-stranded DNA-binding protein	binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA	gene	gene1793	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08970
HSISS4_RS08975	HSISS4_01747		HSISS4_RS08975	1952357	1952584	-	oxidoreductase		gene	gene1794	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08975
HSISS4_RS08980	HSISS4_01748		HSISS4_RS08980	1952599	1953630	-	permease		gene	gene1795	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08980
HSISS4_RS08985	HSISS4_01749		HSISS4_RS08985	1953768	1954391	-	tRNA-binding protein		gene	gene1796	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08985
HSISS4_RS08990	HSISS4_01750		HSISS4_RS08990	1954423	1954947	-	hypothetical protein		gene	gene1797	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08990
HSISS4_RS08995	HSISS4_01751		HSISS4_RS08995	1954951	1955265	-	thiol reductase thioredoxin		gene	gene1798	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS08995
HSISS4_RS09000	HSISS4_01752		HSISS4_RS09000	1955262	1955546	-	membrane protein		gene	gene1799	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09000
HSISS4_RS09005	HSISS4_01753		HSISS4_RS09005	1955646	1956713	+	glutamyl aminopeptidase		gene	gene1800	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09005
HSISS4_RS09010	HSISS4_01754		HSISS4_RS09010	1956729	1957499	+	pyrroline-5-carboxylate reductase		gene	gene1801	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09010
HSISS4_RS09015	HSISS4_01755		HSISS4_RS09015	1957526	1958188	-	hypothetical protein		gene	gene1802	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09015
HSISS4_RS09020	HSISS4_01756		HSISS4_RS09020	1958301	1958747	-	hypothetical protein		gene	gene1803	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09020
HSISS4_RS09025	HSISS4_01757		HSISS4_RS09025	1958825	1959481	-	CAAX amino protease		gene	gene1804	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09025
HSISS4_RS09030	HSISS4_01758		HSISS4_RS09030	1959493	1959690	-	transcriptional regulator		gene	gene1805	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09030
HSISS4_RS09035	HSISS4_01759		HSISS4_RS09035	1959941	1961134	-	acetate kinase		gene	gene1806	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09035
HSISS4_RS09040	HSISS4_01760		HSISS4_RS09040	1961191	1962147	-	adenine methyltransferase		gene	gene1807	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09040
HSISS4_RS09045	HSISS4_01761		HSISS4_RS09045	1962192	1962509	-	Late competence protein ComGG		gene	gene1808	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09045
HSISS4_RS09050	HSISS4_01762		HSISS4_RS09050	1962487	1962924	-	Late competence protein ComGF%2C access of DNA to ComEA		gene	gene1809	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09050
HSISS4_RS09055	HSISS4_01763		HSISS4_RS09055	1962911	1963141	-	Late competence protein ComGE		gene	gene1810	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09055
HSISS4_RS09060	HSISS4_01764		HSISS4_RS09060	1963173	1963592	-	competence protein		gene	gene1811	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09060
HSISS4_RS09065	HSISS4_01765		HSISS4_RS09065	1963561	1963887	-	competence protein ComGC		gene	gene1812	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09065
HSISS4_RS09070	HSISS4_01766		HSISS4_RS09070	1963884	1964747	-	competence protein CglB		gene	gene1813	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09070
HSISS4_RS09075	HSISS4_01767		HSISS4_RS09075	1964866	1965807	-	competence protein CglA		gene	gene1814	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09075
HSISS4_RS09080	HSISS4_01768		HSISS4_RS09080	1965889	1966251	-	DNA-binding protein		gene	gene1815	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09080
HSISS4_RS09085	HSISS4_01769		HSISS4_RS09085	1966414	1970052	-	DNA-directed RNA polymerase subunit beta'		gene	gene1816	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09085
HSISS4_RS09090	HSISS4_01770		HSISS4_RS09090	1970152	1973733	-	DNA-directed RNA polymerase subunit beta		gene	gene1817	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09090
HSISS4_RS09095	HSISS4_01771		HSISS4_RS09095	1974093	1976516	-	multimodular transpeptidase-transglycosylase		gene	gene1818	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09095
HSISS4_RS09100	HSISS4_01772		HSISS4_RS09100	1976618	1977874	+	tyrosine--tRNA ligase	catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr)	gene	gene1819	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09100
HSISS4_RS09105	HSISS4_01773		HSISS4_RS09105	1978001	1979023	-	ketol-acid reductoisomerase		gene	gene1820	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09105
HSISS4_RS09110	HSISS4_01774		HSISS4_RS09110	1979099	1979575	-	acetolactate synthase small subunit		gene	gene1821	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09110
HSISS4_RS09115	HSISS4_01775		HSISS4_RS09115	1979568	1981268	-	acetolactate synthase large subunit	catalyzes the formation of 2-acetolactate from pyruvate%3B also known as acetolactate synthase large subunit	gene	gene1822	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09115
HSISS4_RS09120	HSISS4_01776		HSISS4_RS09120	1981402	1983123	-	dihydroxy-acid dehydratase	catalyzes the dehydration of 2%2C3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis	gene	gene1823	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09120
HSISS4_RS09125	HSISS4_01777		HSISS4_RS09125	1983293	1984960	-	dihydroxyacetone kinase		gene	gene1824	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09125
HSISS4_RS09130	HSISS4_01778		HSISS4_RS09130	1984960	1985325	-	hypothetical protein		gene	gene1825	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09130
HSISS4_RS09135	HSISS4_01779		HSISS4_RS09135	1985437	1986723	-	multi antimicrobial extrusion (MATE) family transporter		gene	gene1826	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09135
HSISS4_RS09140	HSISS4_01780		HSISS4_RS09140	1986784	1988268	-	threonine synthase		gene	gene1827	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09140
HSISS4_RS09145	HSISS4_01781		HSISS4_RS09145	1988428	1989399	-	hypothetical protein		gene	gene1828	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09145
HSISS4_RS09150	HSISS4_01782		HSISS4_RS09150	1989425	1990270	-	hypothetical protein		gene	gene1829	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09150
HSISS4_RS09155	HSISS4_01783		HSISS4_RS09155	1990431	1993019	-	bifunctional acetaldehyde-CoA/alcohol dehydrogenase		gene	gene1830	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09155
HSISS4_RS09160	HSISS4_01784		HSISS4_RS09160	1993159	1995054	-	Neutral endopeptidase O		gene	gene1831	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09160
HSISS4_RS09165	HSISS4_01785		HSISS4_RS09165	1995136	1996761	-	trehalose-6-phosphate hydrolase		gene	gene1832	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09165
HSISS4_RS09170	HSISS4_01786		HSISS4_RS09170	1996816	1998765	-	PTS beta-glucoside transporter subunit EIIBCA	phosphoenolpyruvate-dependent sugar phosphotransferase system%3B catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar%3B IIC forms the translocation channel	gene	gene1833	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09170
HSISS4_RS09175	HSISS4_01787		HSISS4_RS09175	1998922	1999632	+	GntR family transcriptional regulator		gene	gene1834	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09175
HSISS4_RS09180	HSISS4_01788		HSISS4_RS09180	1999686	2000246	-	TIGR01440 family protein		gene	gene1835	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09180
HSISS4_RS09185	HSISS4_01789		HSISS4_RS09185	2000633	2000989	-	hypothetical protein		gene	gene1836	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09185
HSISS4_RS09190	HSISS4_01790		HSISS4_RS09190	2001540	2002343	-	hypothetical protein		gene	gene1837	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09190
HSISS4_RS09195	HSISS4_01791		HSISS4_RS09195	2002477	2003358	-	hypothetical protein		gene	gene1838	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09195
HSISS4_RS09200	HSISS4_01792		HSISS4_RS09200	2003535	2003657	-	transposase		gene	gene1839	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09200
HSISS4_RS09205	HSISS4_01793		HSISS4_RS09205	2003941	2004822	-	fructose-bisphosphate aldolase	catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate	gene	gene1840	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09205
HSISS4_RS09210	HSISS4_r00082		HSISS4_RS09210	2004968	2005053	-	tRNA-Leu		tRNA	gene1841	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09210
HSISS4_RS09215	HSISS4_01795		HSISS4_RS09215	2005245	2006540	-	hypothetical protein		gene	gene1842	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09215
HSISS4_RS09220	HSISS4_01796		HSISS4_RS09220	2006789	2007175	-	50S ribosomal protein L17		gene	gene1843	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09220
HSISS4_RS09225	HSISS4_01797		HSISS4_RS09225	2007193	2008131	-	DNA-directed RNA polymerase subunit alpha		gene	gene1844	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09225
HSISS4_RS09230	HSISS4_01798		HSISS4_RS09230	2008180	2008563	-	30S ribosomal protein S11		gene	gene1845	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09230
HSISS4_RS09235	HSISS4_01799		HSISS4_RS09235	2008590	2008955	-	30S ribosomal protein S13		gene	gene1846	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09235
HSISS4_RS09240	HSISS4_01801		HSISS4_RS09240	2009115	2009333	-	translation initiation factor IF-1		gene	gene1847	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09240
HSISS4_RS09245	HSISS4_01802		HSISS4_RS09245	2009451	2010089	-	adenylate kinase		gene	gene1848	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09245
HSISS4_RS09250	HSISS4_01803		HSISS4_RS09250	2010221	2011516	-	preprotein translocase subunit SecY		gene	gene1849	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09250
HSISS4_RS09255	HSISS4_01804		HSISS4_RS09255	2011533	2011973	-	50S ribosomal protein L15		gene	gene1850	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09255
HSISS4_RS09260	HSISS4_01805		HSISS4_RS09260	2012101	2012283	-	50S ribosomal protein L30		gene	gene1851	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09260
HSISS4_RS09265	HSISS4_01806		HSISS4_RS09265	2012298	2012792	-	30S ribosomal protein S5		gene	gene1852	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09265
HSISS4_RS09270	HSISS4_01807		HSISS4_RS09270	2012811	2013176	-	50S ribosomal protein L18		gene	gene1853	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09270
HSISS4_RS09275	HSISS4_01808		HSISS4_RS09275	2013257	2013793	-	50S ribosomal protein L6		gene	gene1854	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09275
HSISS4_RS09280	HSISS4_01809		HSISS4_RS09280	2013920	2014318	-	30S ribosomal protein S8		gene	gene1855	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09280
HSISS4_RS09285	HSISS4_01810	rpsN	rpsN	2014441	2014626	-	30S ribosomal protein S14 type Z	located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group appear to contain the zinc-binding motif	gene	gene1856	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09285
HSISS4_RS09290	HSISS4_01811		HSISS4_RS09290	2014644	2015186	-	50S ribosomal protein L5		gene	gene1857	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09290
HSISS4_RS09295	HSISS4_01812		HSISS4_RS09295	2015213	2015518	-	50S ribosomal protein L24		gene	gene1858	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09295
HSISS4_RS09300	HSISS4_01813		HSISS4_RS09300	2015599	2015967	-	50S ribosomal protein L14		gene	gene1859	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09300
HSISS4_RS09305	HSISS4_01814		HSISS4_RS09305	2015992	2016252	-	30S ribosomal protein S17		gene	gene1860	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09305
HSISS4_RS09310	HSISS4_01815		HSISS4_RS09310	2016280	2016486	-	50S ribosomal protein L29		gene	gene1861	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09310
HSISS4_RS09315	HSISS4_01816		HSISS4_RS09315	2016496	2016909	-	50S ribosomal protein L16		gene	gene1862	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09315
HSISS4_RS09320	HSISS4_01817		HSISS4_RS09320	2016913	2017566	-	30S ribosomal protein S3		gene	gene1863	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09320
HSISS4_RS09325	HSISS4_01818		HSISS4_RS09325	2017579	2017923	-	50S ribosomal protein L22		gene	gene1864	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09325
HSISS4_RS09330	HSISS4_01819		HSISS4_RS09330	2017939	2018217	-	30S ribosomal protein S19		gene	gene1865	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09330
HSISS4_RS09335	HSISS4_01820	rplB	rplB	2018311	2019144	-	50S ribosomal protein L2	one of the primary rRNA-binding proteins%3B required for association of the 30S and 50S subunits to form the 70S ribosome%2C for tRNA binding and peptide bond formation	gene	gene1866	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09335
HSISS4_RS09340	HSISS4_01821		HSISS4_RS09340	2019162	2019458	-	50S ribosomal protein L23		gene	gene1867	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09340
HSISS4_RS09345	HSISS4_01822		HSISS4_RS09345	2019458	2020081	-	50S ribosomal protein L4		gene	gene1868	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09345
HSISS4_RS09350	HSISS4_01823		HSISS4_RS09350	2020106	2020732	-	50S ribosomal protein L3		gene	gene1869	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09350
HSISS4_RS09355	HSISS4_01824		HSISS4_RS09355	2020847	2021155	-	30S ribosomal protein S10		gene	gene1870	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09355
HSISS4_RS09360	HSISS4_01825		HSISS4_RS09360	2021399	2022400	-	Holliday junction DNA helicase RuvB		gene	gene1871	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09360
HSISS4_RS09365	HSISS4_01826		HSISS4_RS09365	2022481	2024304	-	acyltransferase		gene	gene1872	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09365
HSISS4_RS09370	HSISS4_01827		HSISS4_RS09370	2024301	2024711	-	membrane protein		gene	gene1873	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09370
HSISS4_RS09375	HSISS4_01828		HSISS4_RS09375	2024708	2025142	-	protein-tyrosine-phosphatase		gene	gene1874	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09375
HSISS4_RS09380	HSISS4_01829		HSISS4_RS09380	2025418	2026710	-	adenylosuccinate synthase		gene	gene1875	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09380
HSISS4_RS09385	HSISS4_01830		HSISS4_RS09385	2026946	2027452	-	DNA topology modulation protein FlaR		gene	gene1876	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09385
HSISS4_RS09390	HSISS4_r00083		HSISS4_RS09390	2027639	2027711	-	tRNA-Lys		tRNA	gene1877	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09390
HSISS4_RS09395	HSISS4_RS09395	ssrS	ssrS	2027712	2027907	-	6S RNA		ncRNA	gene1878	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09395
HSISS4_RS09400	HSISS4_01831		HSISS4_RS09400	2027994	2029262	-	hypothetical protein		gene	gene1879	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09400
HSISS4_RS09405	HSISS4_01832		HSISS4_RS09405	2029433	2029621	+	50S ribosomal protein L28		gene	gene1880	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09405
HSISS4_RS09410	HSISS4_01833		HSISS4_RS09410	2029748	2030014	+	hypothetical protein		gene	gene1881	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09410
HSISS4_RS09415	HSISS4_01834		HSISS4_RS09415	2030014	2030433	+	crossover junction endodeoxyribonuclease RuvA		gene	gene1882	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09415
HSISS4_RS09420	HSISS4_01835		HSISS4_RS09420	2030539	2030844	+	hypothetical protein		gene	gene1883	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09420
HSISS4_RS09425	HSISS4_01836		HSISS4_RS09425	2031057	2032703	+	hypothetical protein		gene	gene1884	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09425
HSISS4_RS09430	HSISS4_01837		HSISS4_RS09430	2032802	2035006	+	anaerobic ribonucleoside triphosphate reductase		gene	gene1885	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09430
HSISS4_RS09435	HSISS4_01839		HSISS4_RS09435	2035229	2035729	+	GNAT family acetyltransferase		gene	gene1886	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09435
HSISS4_RS09440	HSISS4_01840		HSISS4_RS09440	2035734	2036339	+	ribonucleotide reductase of class III (anaerobic)%2C activating protein		gene	gene1887	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09440
HSISS4_RS09445	HSISS4_01841		HSISS4_RS09445	2036370	2037101	-	hypothetical protein		gene	gene1888	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09445
HSISS4_RS09450	HSISS4_01842		HSISS4_RS09450	2037187	2038128	-	hypothetical protein		gene	gene1889	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09450
HSISS4_RS09455	HSISS4_01843	aspS	aspS	2038121	2039872	-	aspartate--tRNA ligase	catalyzes a two-step reaction%2C first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes	gene	gene1890	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09455
HSISS4_RS09460	HSISS4_01844		HSISS4_RS09460	2039982	2040404	-	hypothetical protein		gene	gene1891	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09460
HSISS4_RS09465	HSISS4_01845		HSISS4_RS09465	2040412	2041692	-	histidine--tRNA ligase		gene	gene1892	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09465
HSISS4_RS09470	HSISS4_RS09470		HSISS4_RS09470	2041845	2043206	-	PTS beta-glucoside transporter subunit IIABC	internal stop	gene	gene1893	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09470
HSISS4_RS09475	HSISS4_01848		HSISS4_RS09475	2043272	2044384	-	hypothetical protein		gene	gene1894	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09475
HSISS4_RS09480	HSISS4_01849		HSISS4_RS09480	2044615	2044797	+	50S ribosomal protein L32		gene	gene1895	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09480
HSISS4_RS09485	HSISS4_01850		HSISS4_RS09485	2044813	2044962	+	50S ribosomal protein L33		gene	gene1896	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09485
HSISS4_RS09490	HSISS4_01851		HSISS4_RS09490	2045355	2046859	+	protein kinase	frameshifted	gene	gene1897	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09490
HSISS4_RS09495	HSISS4_01853		HSISS4_RS09495	2047212	2047883	+	phage-associated cell wall hydrolase		gene	gene1898	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09495
HSISS4_RS09500	HSISS4_01854		HSISS4_RS09500	2047907	2048632	+	phage-associated cell wall hydrolase		gene	gene1899	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09500
HSISS4_RS09505	HSISS4_01856		HSISS4_RS09505	2049652	2050260	+	UDP-N-acetyl glucosamine 2-epimerase		gene	gene1900	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09505
HSISS4_RS09510	HSISS4_01857		HSISS4_RS09510	2050290	2050529	+	1-phosphofructokinase		gene	gene1901	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09510
HSISS4_RS09515	HSISS4_01858		HSISS4_RS09515	2050545	2051582	+	diguanylate cyclase		gene	gene1902	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09515
HSISS4_RS09520	HSISS4_01859		HSISS4_RS09520	2051530	2052543	+	glycosyl transferase		gene	gene1903	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09520
HSISS4_RS09525	HSISS4_01860		HSISS4_RS09525	2052533	2054758	+	glycosyl transferase		gene	gene1904	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09525
HSISS4_RS09530	HSISS4_01861		HSISS4_RS09530	2054755	2056695	+	hypothetical protein		gene	gene1905	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09530
HSISS4_RS09535	HSISS4_01862		HSISS4_RS09535	2057327	2058258	+	hypothetical protein	frameshifted	gene	gene1906	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09535
HSISS4_RS09540	HSISS4_01864		HSISS4_RS09540	2058295	2059050	+	hypothetical protein		gene	gene1907	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09540
HSISS4_RS09545	HSISS4_01865		HSISS4_RS09545	2059025	2059525	+	hypothetical protein		gene	gene1908	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09545
HSISS4_RS09550	HSISS4_01866		HSISS4_RS09550	2059761	2060369	-	coenzyme A pyrophosphatase		gene	gene1909	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09550
HSISS4_RS09555	HSISS4_01867		HSISS4_RS09555	2060532	2060858	+	PadR family transcriptional regulator		gene	gene1910	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09555
HSISS4_RS09560	HSISS4_01868		HSISS4_RS09560	2060845	2061429	+	membrane protein		gene	gene1911	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09560
HSISS4_RS09565	HSISS4_01869		HSISS4_RS09565	2061399	2062271	+	hypothetical protein		gene	gene1912	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09565
HSISS4_RS09570	HSISS4_01870		HSISS4_RS09570	2062309	2064678	-	membrane protein		gene	gene1913	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09570
HSISS4_RS09575	HSISS4_01871		HSISS4_RS09575	2064807	2065346	+	TetR family transcriptional regulator		gene	gene1914	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09575
HSISS4_RS09580	HSISS4_01872		HSISS4_RS09580	2065423	2065785	-	hypothetical protein		gene	gene1915	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09580
HSISS4_RS09585	HSISS4_01873		HSISS4_RS09585	2065901	2066089	+	hypothetical protein		gene	gene1916	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09585
HSISS4_RS09590	HSISS4_01874		HSISS4_RS09590	2066304	2066915	-	30S ribosomal protein S4		gene	gene1917	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09590
HSISS4_RS09595	HSISS4_01875		HSISS4_RS09595	2067114	2067416	-	hypothetical protein		gene	gene1918	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09595
HSISS4_RS09600	HSISS4_01876		HSISS4_RS09600	2067446	2068807	-	replicative DNA helicase		gene	gene1919	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09600
HSISS4_RS09605	HSISS4_01877		HSISS4_RS09605	2068851	2069309	-	50S ribosomal protein L9		gene	gene1920	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09605
HSISS4_RS09610	HSISS4_01878		HSISS4_RS09610	2069311	2071275	-	DHH family phosphoesterase		gene	gene1921	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09610
HSISS4_RS09615	HSISS4_01879		HSISS4_RS09615	2071349	2073250	-	tRNA uridine(34) 5-carboxymethylaminomethyl synthesis enzyme MnmG		gene	gene1922	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09615
HSISS4_RS09620	HSISS4_01880		HSISS4_RS09620	2073432	2074043	-	multiple antibiotic resistance protein marC		gene	gene1923	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09620
HSISS4_RS09625	HSISS4_01881		HSISS4_RS09625	2074063	2075184	-	tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase		gene	gene1924	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09625
HSISS4_RS09630	HSISS4_01882		HSISS4_RS09630	2075329	2077038	-	hypothetical protein		gene	gene1925	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09630
HSISS4_RS09635	HSISS4_01883		HSISS4_RS09635	2077174	2077872	-	hypothetical protein		gene	gene1926	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09635
HSISS4_RS09640	HSISS4_01884		HSISS4_RS09640	2078056	2078628	-	aggregation promoting factor		gene	gene1927	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09640
HSISS4_RS09645	HSISS4_01885		HSISS4_RS09645	2078929	2079723	-	transmembrane component		gene	gene1928	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09645
HSISS4_RS09650	HSISS4_01886	cbiO	cbiO	2079716	2080558	-	energy-coupling factor transporter ATPase	with CbiNQ forms the ABC transporter for cobalt import%3B Bacillus spp. have two adjacent copies of this gene	gene	gene1929	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09650
HSISS4_RS09655	HSISS4_01887		HSISS4_RS09655	2080534	2081364	-	energy-coupling factor transporter ATPase		gene	gene1930	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09655
HSISS4_RS09660	HSISS4_01888		HSISS4_RS09660	2081377	2081919	-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase		gene	gene1931	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09660
HSISS4_RS09665	HSISS4_01889		HSISS4_RS09665	2081932	2082789	-	membrane protein		gene	gene1932	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09665
HSISS4_RS09670	HSISS4_01890		HSISS4_RS09670	2082848	2084125	-	peptidase M16		gene	gene1933	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09670
HSISS4_RS09675	HSISS4_01891		HSISS4_RS09675	2084127	2085377	-	protease		gene	gene1934	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09675
HSISS4_RS09680	HSISS4_01892		HSISS4_RS09680	2085455	2085832	+	hypothetical protein		gene	gene1935	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09680
HSISS4_RS09685	HSISS4_01893		HSISS4_RS09685	2085835	2086935	+	DNA replication/repair protein RecF		gene	gene1936	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09685
HSISS4_RS09690	HSISS4_01894		HSISS4_RS09690	2087117	2088598	-	IMP dehydrogenase	catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate	gene	gene1937	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09690
HSISS4_RS09695	HSISS4_01895		HSISS4_RS09695	2088898	2090154	+	transposase		gene	gene1938	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09695
HSISS4_RS09700	HSISS4_01896		HSISS4_RS09700	2090196	2091218	-	tryptophan--tRNA ligase	catalyzes a two-step reaction%2C first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA	gene	gene1939	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09700
HSISS4_RS09705	HSISS4_01897		HSISS4_RS09705	2091647	2092519	+	membrane protein		gene	gene1940	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09705
HSISS4_RS09710	HSISS4_01898		HSISS4_RS09710	2092586	2094208	+	ABC transporter ATP-binding protein		gene	gene1941	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09710
HSISS4_RS09715	HSISS4_01899		HSISS4_RS09715	2094258	2096852	+	ABC transporter permease		gene	gene1942	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09715
HSISS4_RS09720	HSISS4_r00084		HSISS4_RS09720	2096950	2097023	-	tRNA-Asn		tRNA	gene1943	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09720
HSISS4_RS09725	HSISS4_r00085		HSISS4_RS09725	2097046	2097117	-	tRNA-Glu		tRNA	gene1944	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09725
HSISS4_RS09730	HSISS4_r00086		HSISS4_RS09730	2097304	2097377	+	tRNA-Arg		tRNA	gene1945	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09730
HSISS4_RS09735	HSISS4_01900		HSISS4_RS09735	2097402	2098085	-	hypothetical protein		gene	gene1946	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09735
HSISS4_RS09740	HSISS4_01901		HSISS4_RS09740	2098101	2098580	-	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	SPOUT methyltransferase family protein%3B crystal structure shows homodimer%3B in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA	gene	gene1947	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09740
HSISS4_RS09745	HSISS4_01902		HSISS4_RS09745	2098786	2100021	+	serine protease		gene	gene1948	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09745
HSISS4_RS09750	HSISS4_01903		HSISS4_RS09750	2100087	2100854	+	chromosome partitioning protein ParB		gene	gene1949	http://www.ncbi.nlm.nih.gov/gene/?term=HSISS4_RS09750