HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Pfam PF00117 Glutamine amidotransferase class-I 15 196 2.1E-42 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Gene3D G3DSA:3.30.300.10 396 520 4.4E-51 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PANTHER PTHR11922:SF2 1 517 2.1E-288 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 175 188 1.2E-7 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 84 95 1.2E-7 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00096 Glutamine amidotransferase superfamily signature 57 66 1.2E-7 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 SUPERFAMILY SSF54810 400 520 3.79E-50 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Gene3D G3DSA:3.40.50.620 221 395 2.3E-57 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 SUPERFAMILY SSF52317 11 208 3.48E-53 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 10 520 53.957 T 21-04-2016 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 13 202 8.7E-74 T 21-04-2016 IPR004739 GMP synthase, N-terminal GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Pfam PF02540 NAD synthase 219 252 3.9E-7 T 21-04-2016 IPR022310 NAD/GMP synthase HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00097 Anthranilate synthase component II signature 57 66 8.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00097 Anthranilate synthase component II signature 84 95 8.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00097 Anthranilate synthase component II signature 175 188 8.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PANTHER PTHR11922 1 517 2.1E-288 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 210 520 5.2E-152 T 21-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Pfam PF00958 GMP synthase C terminal domain 428 519 1.3E-43 T 21-04-2016 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|UniPathway: UPA00189 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 Gene3D G3DSA:3.40.50.880 8 220 1.5E-63 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 54 68 1.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 13 27 1.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 84 100 1.7E-6 T 21-04-2016 HSISS4_RS05435 a5b312a5d1f0f46652b0253fda3376b1 520 SUPERFAMILY SSF52402 195 413 1.98E-59 T 21-04-2016 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SUPERFAMILY SSF49303 608 707 2.01E-20 T 21-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PANTHER PTHR10066 1 563 1.7E-278 T 21-04-2016 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PANTHER PTHR10066 581 1005 1.7E-278 T 21-04-2016 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Pfam PF00703 Glycosyl hydrolases family 2 220 322 2.7E-11 T 21-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Gene3D G3DSA:2.70.98.10 718 1003 2.6E-87 T 21-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SUPERFAMILY SSF51445 324 611 3.78E-88 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Gene3D G3DSA:2.60.40.320 209 322 5.6E-27 T 21-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SUPERFAMILY SSF49303 220 322 1.24E-16 T 21-04-2016 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SUPERFAMILY SSF74650 717 1003 1.15E-81 T 21-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Gene3D G3DSA:2.60.120.260 8 208 5.0E-68 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Pfam PF02929 Beta galactosidase small chain 733 1001 1.2E-64 T 21-04-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Gene3D G3DSA:2.60.40.320 613 708 5.4E-20 T 21-04-2016 IPR013812 Glycoside hydrolase, family 2/20, immunoglobulin-like beta-sandwich domain GO:0004553|GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PRINTS PR00132 Glycosyl hydrolase family 2 signature 364 382 1.8E-34 T 21-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PRINTS PR00132 Glycosyl hydrolase family 2 signature 333 347 1.8E-34 T 21-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PRINTS PR00132 Glycosyl hydrolase family 2 signature 519 534 1.8E-34 T 21-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PRINTS PR00132 Glycosyl hydrolase family 2 signature 444 459 1.8E-34 T 21-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PRINTS PR00132 Glycosyl hydrolase family 2 signature 146 161 1.8E-34 T 21-04-2016 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PANTHER PTHR10066:SF72 1 563 1.7E-278 T 21-04-2016 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 PANTHER PTHR10066:SF72 581 1005 1.7E-278 T 21-04-2016 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 ProSitePatterns PS00719 Glycosyl hydrolases family 2 signature 1. 374 399 - T 21-04-2016 IPR023230 Glycoside hydrolase, family 2, conserved site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 46 218 5.6E-35 T 21-04-2016 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 444 458 - T 21-04-2016 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SMART SM01038 731 1002 1.3E-111 T 21-04-2016 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Gene3D G3DSA:3.20.20.80 324 611 1.3E-98 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 SUPERFAMILY SSF49785 9 219 4.54E-55 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 324 616 7.5E-143 T 21-04-2016 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS06360 1835a517636f91dab6155ea685e899e3 1005 Pfam PF16353 Domain of unknown function(DUF4981) 623 707 4.1E-17 T 21-04-2016 IPR032312 Beta-galactosidase, domain 4 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 Pfam PF12802 MarR family 43 91 4.6E-9 T 21-04-2016 HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 Gene3D G3DSA:1.10.10.10 4 142 4.7E-34 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 PANTHER PTHR33164 47 145 4.1E-14 T 21-04-2016 HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 101 - T 21-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 SUPERFAMILY SSF46785 12 141 9.26E-25 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01980 87d60a8ff04e5c2be1e072e1befab887 147 SMART SM00347 26 128 2.5E-13 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 SUPERFAMILY SSF48600 2 85 3.36E-21 T 21-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 Gene3D G3DSA:1.20.59.10 1 84 8.3E-26 T 21-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 TIGRFAM TIGR01805 CM_mono_grmpos: chorismate mutase 3 83 4.8E-28 T 21-04-2016 IPR011279 Chorismate mutase, Gram-positive HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 Pfam PF01817 Chorismate mutase type II 7 83 8.9E-23 T 21-04-2016 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 SMART SM00830 7 86 1.6E-25 T 21-04-2016 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626|UniPathway: UPA00120 HSISS4_RS04215 ad0094ef02624976d3eac6f827741b69 94 PANTHER PTHR38041 1 83 1.1E-15 T 21-04-2016 HSISS4_RS03445 2b27346bc3657187c0f4405575ce4f05 300 Pfam PF01183 Glycosyl hydrolases family 25 112 254 2.7E-16 T 21-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 HSISS4_RS03445 2b27346bc3657187c0f4405575ce4f05 300 PANTHER PTHR34135:SF2 68 275 1.4E-46 T 21-04-2016 HSISS4_RS03445 2b27346bc3657187c0f4405575ce4f05 300 PANTHER PTHR34135 68 275 1.4E-46 T 21-04-2016 HSISS4_RS03445 2b27346bc3657187c0f4405575ce4f05 300 SUPERFAMILY SSF51445 70 270 6.04E-36 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03445 2b27346bc3657187c0f4405575ce4f05 300 Gene3D G3DSA:3.20.20.80 68 262 1.4E-35 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 Gene3D G3DSA:3.40.190.10 161 338 5.4E-27 T 21-04-2016 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 PANTHER PTHR30061:SF21 14 406 5.0E-38 T 21-04-2016 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 Gene3D G3DSA:3.40.190.10 33 160 3.0E-23 T 21-04-2016 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 PANTHER PTHR30061 14 406 5.0E-38 T 21-04-2016 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 SUPERFAMILY SSF53850 38 391 4.23E-52 T 21-04-2016 HSISS4_RS04825 9a20b964b0424c78f692d9ebcdb25720 415 Pfam PF13416 Bacterial extracellular solute-binding protein 54 355 1.7E-44 T 21-04-2016 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 PANTHER PTHR26402:SF577 2 127 4.7E-34 T 21-04-2016 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 SMART SM00850 149 243 1.3E-22 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 SUPERFAMILY SSF52172 1 126 1.85E-9 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 Gene3D G3DSA:3.40.50.2300 2 138 4.0E-14 T 21-04-2016 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 Pfam PF00072 Response regulator receiver domain 6 123 2.3E-12 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 SMART SM00448 2 123 2.8E-9 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 Gene3D G3DSA:2.40.50.40 141 208 6.1E-18 T 21-04-2016 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 PANTHER PTHR26402 2 127 4.7E-34 T 21-04-2016 HSISS4_RS02135 28028a244bc8bbe1457c18f3570dbe8e 244 Pfam PF04397 LytTr DNA-binding domain 151 242 1.9E-21 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 Gene3D G3DSA:1.25.10.10 295 359 1.9E-5 T 21-04-2016 IPR011989 Armadillo-like helical HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 Pfam PF13484 4Fe-4S double cluster binding domain 184 246 1.0E-13 T 21-04-2016 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 Gene3D G3DSA:3.30.70.20 183 246 5.8E-4 T 21-04-2016 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 7 336 1.5E-112 T 21-04-2016 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 PANTHER PTHR30002 1 362 1.5E-112 T 21-04-2016 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 PANTHER PTHR30002:SF4 1 362 1.5E-112 T 21-04-2016 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 Pfam PF08331 Domain of unknown function (DUF1730) 54 131 3.4E-16 T 21-04-2016 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 184 195 - T 21-04-2016 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 SUPERFAMILY SSF46548 141 247 4.6E-13 T 21-04-2016 IPR009051 Alpha-helical ferredoxin GO:0051536 HSISS4_RS04435 2d0374169c2635dc5bdd1e3ca6f5827e 372 SUPERFAMILY SSF48371 291 357 5.58E-5 T 21-04-2016 IPR016024 Armadillo-type fold GO:0005488 HSISS4_RS00740 705784c2cd527819300f7e82a972b9a0 191 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 15 83 7.3E-9 T 21-04-2016 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 HSISS4_RS00740 705784c2cd527819300f7e82a972b9a0 191 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 9 188 15.655 T 21-04-2016 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 HSISS4_RS00740 705784c2cd527819300f7e82a972b9a0 191 PANTHER PTHR41322 2 188 3.7E-44 T 21-04-2016 HSISS4_RS00740 705784c2cd527819300f7e82a972b9a0 191 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 13 94 1.6E-30 T 21-04-2016 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 PANTHER PTHR20982 1 185 6.2E-81 T 21-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 SUPERFAMILY SSF55194 1 183 2.75E-70 T 21-04-2016 IPR023584 Ribosome recycling factor domain HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.113 T 21-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 Pfam PF01765 Ribosome recycling factor 21 183 3.4E-63 T 21-04-2016 IPR023584 Ribosome recycling factor domain HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 Gene3D G3DSA:1.10.132.20 66 185 2.0E-43 T 21-04-2016 IPR023584 Ribosome recycling factor domain HSISS4_RS02020 2ad2b0eb9a801694fe5c8ef90574c98a 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 2.6E-72 T 21-04-2016 IPR002661 Ribosome recycling factor GO:0006412 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 3 81 1.1E-15 T 21-04-2016 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 Gene3D G3DSA:3.40.50.150 79 281 1.3E-57 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 213 229 2.6E-21 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 96 106 2.6E-21 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 265 282 2.6E-21 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 67 81 2.6E-21 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 163 175 2.6E-21 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 308 369 1.4E-20 T 21-04-2016 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PANTHER PTHR22807 1 335 6.4E-116 T 21-04-2016 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 Pfam PF01189 16S rRNA methyltransferase RsmB/F 86 281 7.8E-46 T 21-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 PANTHER PTHR22807:SF36 1 335 6.4E-116 T 21-04-2016 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 386 434 6.7E-15 T 21-04-2016 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS04900 e8a606d462c6613211390f654dca52c8 436 SUPERFAMILY SSF53335 2 281 4.67E-61 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Gene3D G3DSA:3.30.1370.50 279 345 1.4E-26 T 21-04-2016 IPR001374 R3H domain GO:0003676 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Gene3D G3DSA:3.30.30.80 1 52 2.3E-19 T 21-04-2016 IPR032782 Jag, N-terminal HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 PANTHER PTHR35800 197 344 7.1E-55 T 21-04-2016 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 PANTHER PTHR35800 1 54 7.1E-55 T 21-04-2016 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 SMART SM01245 3 54 2.0E-22 T 21-04-2016 IPR032782 Jag, N-terminal HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Pfam PF14804 Jag N-terminus 4 52 3.5E-18 T 21-04-2016 IPR032782 Jag, N-terminal HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Gene3D G3DSA:3.30.300.120 202 277 1.5E-21 T 21-04-2016 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Pfam PF01424 R3H domain 286 346 1.4E-16 T 21-04-2016 IPR001374 R3H domain GO:0003676 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 SMART SM00393 268 347 8.5E-18 T 21-04-2016 IPR001374 R3H domain GO:0003676 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 SUPERFAMILY SSF82708 289 346 7.46E-11 T 21-04-2016 IPR001374 R3H domain GO:0003676 HSISS4_RS08785 96e51a46744a4d74582a9c6f6edfb802 347 Pfam PF13083 KH domain 205 274 1.0E-15 T 21-04-2016 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 225 5.1E-25 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 SMART SM00862 151 226 8.4E-25 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 SUPERFAMILY SSF46894 130 227 3.4E-29 T 21-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 SUPERFAMILY SSF52172 2 123 5.41E-42 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 PANTHER PTHR26402 3 228 1.5E-92 T 21-04-2016 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 Gene3D G3DSA:3.40.50.2300 2 125 7.1E-42 T 21-04-2016 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 Pfam PF00072 Response regulator receiver domain 5 114 4.6E-30 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 SMART SM00448 3 113 3.6E-44 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 PANTHER PTHR26402:SF578 3 228 1.5E-92 T 21-04-2016 HSISS4_RS01430 6c5daa604a52d1e956480f81bfe045ff 229 Gene3D G3DSA:1.10.10.10 133 228 2.7E-32 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07310 c3a5db7bf64ea7f412eee736fbd1b347 185 SUPERFAMILY SSF55729 1 157 1.36E-20 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS07310 c3a5db7bf64ea7f412eee736fbd1b347 185 Gene3D G3DSA:3.40.630.30 1 179 4.9E-61 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS07310 c3a5db7bf64ea7f412eee736fbd1b347 185 Pfam PF00583 Acetyltransferase (GNAT) family 60 146 1.3E-4 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Pfam PF03764 Elongation factor G, domain IV 477 596 5.0E-47 T 21-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Gene3D G3DSA:3.30.70.240 597 683 3.1E-34 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115 1 177 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115 301 689 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115 253 281 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.3E-16 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PRINTS PR00315 GTP-binding elongation factor signature 94 105 1.3E-16 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PRINTS PR00315 GTP-binding elongation factor signature 130 139 1.3E-16 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.3E-16 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PRINTS PR00315 GTP-binding elongation factor signature 78 88 1.3E-16 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SUPERFAMILY SSF54211 477 597 2.4E-43 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Pfam PF03144 Elongation factor Tu domain 2 322 389 9.9E-15 T 21-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 110.083 T 21-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Gene3D G3DSA:2.40.30.10 303 403 2.1E-37 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Gene3D G3DSA:3.30.70.870 404 478 6.9E-37 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SMART SM00838 598 685 1.5E-52 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SUPERFAMILY SSF50447 263 400 1.54E-34 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 9.0E-42 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Gene3D G3DSA:3.30.230.10 482 596 2.6E-49 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Pfam PF00679 Elongation factor G C-terminus 599 684 8.7E-31 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SUPERFAMILY SSF54980 601 688 1.2E-30 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SUPERFAMILY SSF54980 400 478 2.09E-24 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Gene3D G3DSA:3.40.50.300 7 285 1.1E-108 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115:SF66 1 177 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115:SF66 301 689 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 PANTHER PTHR23115:SF66 253 281 0.0 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 689 0.0 T 21-04-2016 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 4.1E-70 T 21-04-2016 HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 Pfam PF14492 Elongation Factor G, domain II 402 475 2.9E-33 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SUPERFAMILY SSF52540 6 280 3.61E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 21-04-2016 IPR031157 Tr-type G domain, conserved site HSISS4_RS08585 540ffe8fc8b0fb01001b92b9a241fea5 693 SMART SM00889 478 596 2.5E-72 T 21-04-2016 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 SMART SM00836 450 563 3.1E-42 T 21-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 SUPERFAMILY SSF55190 1 103 1.44E-27 T 21-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 563 27.42 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 SMART SM01016 1 83 4.1E-29 T 21-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PANTHER PTHR11956:SF1 1 563 7.8E-241 T 21-04-2016 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 144 3.9E-19 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 297 318 3.9E-19 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 113 128 3.9E-19 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PRINTS PR01038 Arginyl-tRNA synthetase signature 152 165 3.9E-19 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 PANTHER PTHR11956 1 563 7.8E-241 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 SUPERFAMILY SSF47323 444 563 2.01E-33 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Pfam PF05746 DALR anticodon binding domain 450 563 1.6E-32 T 21-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Gene3D G3DSA:1.10.730.10 444 563 1.0E-37 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 5 563 2.8E-158 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Gene3D G3DSA:3.40.50.620 107 443 1.4E-116 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Pfam PF00750 tRNA synthetases class I (R) 95 435 3.2E-100 T 21-04-2016 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Gene3D G3DSA:3.30.1360.70 3 99 9.0E-32 T 21-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 SUPERFAMILY SSF52374 107 444 3.26E-99 T 21-04-2016 HSISS4_RS00285 92a9492eea0e2b0099a29652280bee1e 563 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 3 83 8.5E-21 T 21-04-2016 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: REACT_71 HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PANTHER PTHR24322 7 134 3.5E-62 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PANTHER PTHR24322 150 182 3.5E-62 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 SUPERFAMILY SSF51735 3 252 9.26E-81 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PANTHER PTHR24322:SF347 7 134 3.5E-62 T 21-04-2016 HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PANTHER PTHR24322:SF347 150 182 3.5E-62 T 21-04-2016 HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 8.8E-10 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.8E-10 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.8E-10 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.8E-39 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 21-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 Gene3D G3DSA:3.40.50.720 2 252 1.4E-82 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 9 251 8.3E-61 T 21-04-2016 HSISS4_RS05330 3fef97d1e20880916ab2b56f142c3a51 254 TIGRFAM TIGR02415 23BDH: acetoin reductases 3 253 1.8E-103 T 21-04-2016 IPR014007 Acetoin reductase GO:0019152|GO:0045150|GO:0055114 KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.304+1.1.1.30|MetaCyc: PWY-6389 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 SUPERFAMILY SSF53244 309 448 1.32E-38 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 SUPERFAMILY SSF53623 103 307 2.62E-54 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 11 446 1.9E-127 T 21-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 SUPERFAMILY SSF51984 10 100 1.96E-18 T 21-04-2016 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Gene3D G3DSA:3.90.190.20 311 444 4.2E-43 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 PANTHER PTHR23135 1 450 5.0E-170 T 21-04-2016 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Pfam PF02875 Mur ligase family, glutamate ligase domain 310 385 3.5E-10 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 PANTHER PTHR23135:SF2 1 450 5.0E-170 T 21-04-2016 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Pfam PF08245 Mur ligase middle domain 117 290 3.9E-34 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Gene3D G3DSA:3.40.1190.10 102 309 4.9E-60 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 448 36.072 T 21-04-2016 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS03620 caf2c23f6ea9ce6add600b04f6945606 450 Gene3D G3DSA:3.40.50.720 6 100 4.5E-20 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS00695 f36de2def6ceb4ca84e7b4ae866eeada 157 Pfam PF07155 ECF-type riboflavin transporter, S component 5 151 3.6E-28 T 21-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 SMART SM00363 352 414 1.9E-5 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Pfam PF01479 S4 domain 356 399 3.5E-9 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Gene3D G3DSA:3.40.50.620 3 231 6.7E-100 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Gene3D G3DSA:3.10.290.10 316 418 3.5E-32 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 1.3E-27 T 21-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 1.3E-27 T 21-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 1.3E-27 T 21-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 215 227 1.3E-27 T 21-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 SUPERFAMILY SSF55174 321 417 1.7E-23 T 21-04-2016 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Gene3D G3DSA:1.10.240.10 232 315 2.7E-42 T 21-04-2016 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Pfam PF00579 tRNA synthetases class I (W and Y) 28 322 2.7E-82 T 21-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 SUPERFAMILY SSF52374 2 322 1.09E-107 T 21-04-2016 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 44.492 T 21-04-2016 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 417 1.4E-128 T 21-04-2016 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1|Reactome: REACT_71 HSISS4_RS09100 4b5b72daf1d4f2ee24094d289c0ba2da 418 PANTHER PTHR11766 1 415 5.6E-205 T 21-04-2016 IPR024088 Tyrosine-tRNA ligase, bacterial-type GO:0004831 KEGG: 00970+6.1.1.1 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 TIGRFAM TIGR00260 thrC: threonine synthase 83 442 1.2E-70 T 21-04-2016 IPR004450 Threonine synthase-like HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 101 413 8.5E-14 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314 54 343 1.4E-123 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314 27 38 1.4E-123 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314 373 433 1.4E-123 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 Pfam PF14821 Threonine synthase N terminus 5 80 2.8E-21 T 21-04-2016 IPR029144 Threonine synthase, N-terminal HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 SUPERFAMILY SSF53686 3 491 7.84E-145 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 Gene3D G3DSA:3.40.50.1100 122 203 2.6E-10 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 Gene3D G3DSA:3.90.1380.10 4 85 1.6E-26 T 21-04-2016 IPR029144 Threonine synthase, N-terminal HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 Gene3D G3DSA:3.40.50.1100 204 443 9.3E-91 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314:SF1 54 343 1.4E-123 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314:SF1 27 38 1.4E-123 T 21-04-2016 HSISS4_RS09140 a85a2e9267c0cb81537a614063000694 494 PANTHER PTHR10314:SF1 373 433 1.4E-123 T 21-04-2016 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 77 96 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 409 422 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 395 409 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 199 217 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 377 395 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 274 295 4.4E-26 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 Gene3D G3DSA:3.40.50.10490 201 418 1.1E-92 T 21-04-2016 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 203 216 - T 21-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 Pfam PF00342 Phosphoglucose isomerase 77 426 6.4E-27 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 PANTHER PTHR11469 57 447 1.4E-154 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 Gene3D G3DSA:3.40.50.10490 69 200 4.8E-27 T 21-04-2016 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 SUPERFAMILY SSF53697 6 448 3.41E-137 T 21-04-2016 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 409 426 - T 21-04-2016 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS00930 d9bb23c8da6e3f6f1a855ab1b82ab7ff 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 436 25.213 T 21-04-2016 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 PANTHER PTHR33569:SF1 2 99 1.5E-37 T 21-04-2016 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 7.1E-44 T 21-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 PANTHER PTHR33569 2 99 1.5E-37 T 21-04-2016 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 Gene3D G3DSA:3.30.280.10 1 100 1.2E-44 T 21-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 PIRSF PIRSF001223 1 100 8.2E-51 T 21-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 Pfam PF00547 Urease, gamma subunit 1 99 2.9E-44 T 21-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 SUPERFAMILY SSF54111 1 99 5.76E-43 T 21-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 3.0E-47 T 21-04-2016 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01310 5a22aa9b2b65d8f9e5d243a093f70e36 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.599 T 21-04-2016 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 Pfam PF01039 Carboxyl transferase domain 67 247 4.4E-20 T 21-04-2016 IPR000022 Carboxyl transferase KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 168 186 1.4E-35 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 205 222 1.4E-35 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 148 1.4E-35 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 256 265 1.4E-35 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 234 245 1.4E-35 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 286 39.072 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PANTHER PTHR22855:SF17 29 284 5.5E-138 T 21-04-2016 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 26 284 9.3E-107 T 21-04-2016 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 Gene3D G3DSA:3.90.226.10 29 284 1.8E-69 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 PANTHER PTHR22855 29 284 5.5E-138 T 21-04-2016 HSISS4_RS01835 557e9175a0aa1350a56dd471882843bd 288 SUPERFAMILY SSF52096 34 284 3.27E-75 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 SUPERFAMILY SSF109604 336 485 5.83E-28 T 21-04-2016 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Gene3D G3DSA:3.30.1370.10 235 315 1.0E-8 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 SMART SM00471 347 453 4.4E-13 T 21-04-2016 IPR003607 HD/PDEase domain HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 SMART SM00322 223 290 2.1E-8 T 21-04-2016 IPR004087 K Homology domain GO:0003676 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 SUPERFAMILY SSF54791 223 318 2.13E-17 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 PANTHER PTHR12826 202 534 8.9E-140 T 21-04-2016 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 TIGRFAM TIGR00277 HDIG: HDIG domain 347 424 5.6E-24 T 21-04-2016 IPR006675 HDIG domain HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Pfam PF12072 Domain of unknown function (DUF3552) 3 220 1.3E-46 T 21-04-2016 IPR022711 Ribonuclease Y, N-terminal HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Hamap MF_00335 Ribonuclease Y [rny]. 2 535 24.914 T 21-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Gene3D G3DSA:1.10.3210.10 331 511 2.8E-43 T 21-04-2016 IPR006674 HD domain HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Pfam PF01966 HD domain 352 442 7.9E-19 T 21-04-2016 IPR006674 HD domain HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 5 535 1.1E-231 T 21-04-2016 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 HSISS4_RS01850 5d6525eebca1c8b7bdce1bcddf3a74db 535 Pfam PF00013 KH domain 227 283 5.6E-7 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 Pfam PF13419 Haloacid dehalogenase-like hydrolase 92 216 3.0E-17 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 130 143 1.1E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 177 1.1E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 1.1E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 SUPERFAMILY SSF56784 6 245 9.14E-33 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 116 212 5.7E-6 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 Gene3D G3DSA:3.40.50.1000 6 245 6.2E-33 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 139 197 1.3E-7 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS08935 dee52fcecbdcf874c2bbefe3a62ab8e0 250 PANTHER PTHR12725 6 246 7.1E-26 T 21-04-2016 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 21-04-2016 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 SMART SM00493 80 165 3.1E-13 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 PANTHER PTHR30446 1 198 5.6E-110 T 21-04-2016 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 Pfam PF02132 RecR protein 39 78 2.1E-14 T 21-04-2016 IPR023628 Recombination protein RecR, C4-type zinc finger HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 PANTHER PTHR30446:SF0 1 198 5.6E-110 T 21-04-2016 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 6.9E-86 T 21-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 Pfam PF13662 Toprim domain 81 171 4.6E-23 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 SUPERFAMILY SSF111304 1 198 1.83E-73 T 21-04-2016 IPR023627 Recombination protein RecR HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 100.76 T 21-04-2016 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 HSISS4_RS02895 055d54251d85608800be4988fc0e3b60 198 Gene3D G3DSA:3.40.50.140 119 170 8.6E-4 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 Pfam PF09190 DALR domain 344 396 1.3E-17 T 21-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 SUPERFAMILY SSF47323 330 446 1.31E-33 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 5.2E-29 T 21-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 5.2E-29 T 21-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 5.2E-29 T 21-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 5.2E-29 T 21-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 447 37.512 T 21-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 PANTHER PTHR10890 2 444 7.4E-225 T 21-04-2016 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 Gene3D G3DSA:3.40.50.620 20 307 1.0E-105 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 446 1.3E-170 T 21-04-2016 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16|Reactome: REACT_71 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 SMART SM00840 344 398 1.8E-16 T 21-04-2016 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 1.3E-132 T 21-04-2016 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 SUPERFAMILY SSF52374 3 314 1.98E-98 T 21-04-2016 HSISS4_RS00525 f0df93b7c997e9555a9b3b2b70e41a58 447 Gene3D G3DSA:1.20.120.640 309 390 1.4E-16 T 21-04-2016 HSISS4_RS03260 354272723b3dc42cd538c10ff2637fde 139 Pfam PF12182 Bacterial lipoprotein 56 139 8.4E-29 T 21-04-2016 IPR020961 Domain of unknown function DUF3642, lipoprotein HSISS4_RS03260 354272723b3dc42cd538c10ff2637fde 139 Gene3D G3DSA:2.40.128.50 53 139 3.7E-37 T 21-04-2016 IPR027279 D-aminopeptidase/lipoprotein domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:3.30.420.140 309 434 1.5E-49 T 21-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SUPERFAMILY SSF47781 454 542 1.56E-24 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 PANTHER PTHR10724 1 708 7.0E-302 T 21-04-2016 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 PANTHER PTHR10724:SF1 1 708 7.0E-302 T 21-04-2016 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Pfam PF09371 Tex-like protein N-terminal domain 9 189 1.0E-62 T 21-04-2016 IPR018974 Tex-like protein, N-terminal HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Pfam PF12836 Helix-hairpin-helix motif 475 539 8.1E-26 T 21-04-2016 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SMART SM00732 309 408 4.1E-37 T 21-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:2.40.50.140 618 703 3.1E-26 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Pfam PF00575 S1 RNA binding domain 633 702 2.6E-15 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SUPERFAMILY SSF53098 305 453 1.46E-47 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:1.10.150.310 483 614 6.2E-45 T 21-04-2016 IPR023097 Tex RuvX-like domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Pfam PF16921 Tex protein YqgF-like domain 309 435 2.1E-53 T 21-04-2016 IPR032639 Tex protein, YqgF-like domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SUPERFAMILY SSF158832 4 303 3.66E-97 T 21-04-2016 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:1.10.3500.10 110 305 5.1E-84 T 21-04-2016 IPR023323 Tex-like domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:1.10.3500.10 435 482 5.1E-84 T 21-04-2016 IPR023323 Tex-like domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 Gene3D G3DSA:1.10.10.650 2 109 2.1E-40 T 21-04-2016 IPR023319 Tex-like protein, HTH domain HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SMART SM00316 633 704 1.1E-21 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SUPERFAMILY SSF50249 620 704 2.61E-22 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS03315 c4dc92d27dbc93b44047a7cd8bdddadb 710 SUPERFAMILY SSF47781 544 616 7.89E-17 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 143 199 2.5E-5 T 21-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 19 112 1.6E-17 T 21-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 PANTHER PTHR41299:SF1 3 210 1.4E-46 T 21-04-2016 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 16 204 1.2E-51 T 21-04-2016 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 SUPERFAMILY SSF63999 1 127 3.79E-34 T 21-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 SMART SM00983 139 202 2.3E-15 T 21-04-2016 IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|UniPathway: UPA00060 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 PANTHER PTHR41299 3 210 1.4E-46 T 21-04-2016 HSISS4_RS08615 55b96caa706041cbdb91260d5eed10eb 210 Gene3D G3DSA:3.40.50.10240 2 113 1.2E-25 T 21-04-2016 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 PANTHER PTHR30055:SF2 8 198 2.9E-22 T 21-04-2016 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 37 68 - T 21-04-2016 IPR023772 DNA-binding HTH domain, TetR-type, conserved site HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 PANTHER PTHR30055 8 198 2.9E-22 T 21-04-2016 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 Gene3D G3DSA:1.10.357.10 22 205 7.9E-32 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.6E-9 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.6E-9 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 SUPERFAMILY SSF46689 20 94 1.16E-14 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05175 90d1c235aca74be8a28998522afd6dd8 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 6.7E-15 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 PANTHER PTHR11803 1 126 1.5E-56 T 21-04-2016 IPR006175 YjgF/YER057c/UK114 family HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 Gene3D G3DSA:3.30.1330.40 3 123 1.7E-47 T 21-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 SUPERFAMILY SSF55298 2 125 4.08E-45 T 21-04-2016 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 Pfam PF01042 Endoribonuclease L-PSP 8 124 3.9E-43 T 21-04-2016 IPR006175 YjgF/YER057c/UK114 family HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 PANTHER PTHR11803:SF13 1 126 1.5E-56 T 21-04-2016 HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 123 7.0E-53 T 21-04-2016 IPR006056 RidA family HSISS4_RS05575 2a57ae602df0662b78d09d1ce93aa7c2 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 101 119 - T 21-04-2016 IPR019897 RidA, conserved site HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 Gene3D G3DSA:1.20.1250.20 7 194 1.2E-24 T 21-04-2016 HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 PANTHER PTHR11360:SF135 2 403 1.7E-136 T 21-04-2016 HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 PANTHER PTHR11360 2 403 1.7E-136 T 21-04-2016 HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 SUPERFAMILY SSF103473 5 403 2.35E-58 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 Pfam PF07690 Major Facilitator Superfamily 19 286 4.7E-34 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS02095 439cb82c95109f943923fc01dd73ea87 406 Gene3D G3DSA:1.20.1250.20 221 401 1.2E-22 T 21-04-2016 HSISS4_RS01050 7a32894b59391bae064c49823bd99b89 137 Pfam PF11208 Protein of unknown function (DUF2992) 8 137 1.7E-40 T 21-04-2016 IPR016787 Uncharacterised conserved protein UCP021328 HSISS4_RS01050 7a32894b59391bae064c49823bd99b89 137 PIRSF PIRSF021328 3 137 1.8E-39 T 21-04-2016 IPR016787 Uncharacterised conserved protein UCP021328 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 SUPERFAMILY SSF56024 75 188 9.1E-12 T 21-04-2016 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Pfam PF00271 Helicase conserved C-terminal domain 449 544 1.6E-13 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 SMART SM00487 220 408 4.8E-7 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Gene3D G3DSA:3.40.50.300 429 585 1.1E-25 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Gene3D G3DSA:3.40.50.300 221 384 2.3E-20 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 PANTHER PTHR30195 50 934 7.4E-71 T 21-04-2016 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Gene3D G3DSA:3.30.870.10 71 189 3.8E-11 T 21-04-2016 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 SMART SM00490 465 546 6.9E-12 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Pfam PF11907 Domain of unknown function (DUF3427) 687 959 5.0E-89 T 21-04-2016 IPR021835 Protein of unknown function DUF3427 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Pfam PF04851 Type III restriction enzyme, res subunit 222 373 8.8E-29 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 Pfam PF13091 PLD-like domain 76 182 8.7E-14 T 21-04-2016 IPR025202 Phospholipase D-like domain HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 SUPERFAMILY SSF52540 270 567 2.59E-41 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03400 aceddfadf0a9e4991ea20a5b050cc27b 961 PANTHER PTHR30195:SF16 50 934 7.4E-71 T 21-04-2016 HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 Pfam PF00005 ABC transporter 24 180 3.4E-28 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 PANTHER PTHR24220 5 253 2.1E-109 T 21-04-2016 HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 Gene3D G3DSA:3.40.50.300 3 238 1.3E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 SMART SM00382 33 231 7.7E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 PANTHER PTHR24220:SF534 5 253 2.1E-109 T 21-04-2016 HSISS4_RS00980 87d40ebbc85fbc88bf36b7940f7646b0 267 SUPERFAMILY SSF52540 2 237 3.91E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 191 258 0.36 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 273 340 2.0E-5 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 457 523 0.024 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 635 701 1.2 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 791 851 4.4 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 SMART SM00287 714 779 0.12 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 42 7.3E-14 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF04650 YSIRK type signal peptide 9 33 7.3E-12 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 711 773 3.8E-21 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 452 516 1.5E-21 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 788 850 1.2E-20 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 189 251 2.2E-13 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 270 332 1.9E-20 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08460 Bacterial SH3 domain 632 694 1.3E-20 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08481 GBS Bsp-like repeat 347 437 1.3E-29 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS02120 4a904d82e721e69037d2e771d65d697e 851 Pfam PF08481 GBS Bsp-like repeat 530 619 6.9E-27 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 Pfam PF00297 Ribosomal protein L3 97 176 1.1E-14 T 21-04-2016 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 Gene3D G3DSA:2.40.30.10 155 206 6.3E-15 T 21-04-2016 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 Gene3D G3DSA:2.40.30.10 4 33 6.3E-15 T 21-04-2016 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 Gene3D G3DSA:4.10.960.10 82 154 8.4E-33 T 21-04-2016 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 SUPERFAMILY SSF50447 1 205 5.92E-79 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 PANTHER PTHR11229 1 208 2.5E-108 T 21-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 100 123 - T 21-04-2016 IPR019926 Ribosomal protein L3, conserved site HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 201 1.6E-83 T 21-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09350 ae9d6d713df87a1dc11b653549833af1 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 204 38.245 T 21-04-2016 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00865 14ac8da745bf53024aa7a051d04a8eb0 420 PANTHER PTHR30508 1 417 1.1E-134 T 21-04-2016 HSISS4_RS00865 14ac8da745bf53024aa7a051d04a8eb0 420 SUPERFAMILY SSF101960 5 418 7.19E-117 T 21-04-2016 HSISS4_RS00865 14ac8da745bf53024aa7a051d04a8eb0 420 PANTHER PTHR30508:SF0 1 417 1.1E-134 T 21-04-2016 HSISS4_RS00865 14ac8da745bf53024aa7a051d04a8eb0 420 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 132 408 1.1E-79 T 21-04-2016 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 HSISS4_RS00865 14ac8da745bf53024aa7a051d04a8eb0 420 Pfam PF01458 Uncharacterized protein family (UPF0051) 167 392 5.3E-59 T 21-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 SMART SM00062 39 263 7.6E-46 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 62 75 - T 21-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 PANTHER PTHR18966 35 265 5.6E-32 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 PANTHER PTHR18966:SF208 35 265 5.6E-32 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 SUPERFAMILY SSF53850 1 261 1.37E-48 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 Gene3D G3DSA:3.40.190.10 123 219 2.7E-44 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 Gene3D G3DSA:3.40.190.10 34 122 2.9E-22 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 Gene3D G3DSA:3.40.190.10 220 260 2.9E-22 T 21-04-2016 HSISS4_RS04990 cb9d7ca6887ef83da7c594f9cdadbad4 282 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 260 5.5E-46 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:3.40.50.300 186 284 5.8E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:3.40.50.300 3 107 5.8E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 4 767 0.0 T 21-04-2016 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:1.10.10.160 112 185 5.2E-26 T 21-04-2016 IPR013986 DExx box DNA helicase domain HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Pfam PF13361 UvrD-like helicase C-terminal domain 276 619 4.2E-75 T 21-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 SUPERFAMILY SSF52540 1 645 5.32E-178 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 PANTHER PTHR11070 1 513 1.3E-232 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 PANTHER PTHR11070 532 654 1.3E-232 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Pfam PF00580 UvrD/REP helicase N-terminal domain 8 270 7.8E-83 T 21-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:1.10.486.10 387 543 1.8E-45 T 21-04-2016 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 PANTHER PTHR11070:SF7 1 513 1.3E-232 T 21-04-2016 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 PANTHER PTHR11070:SF7 532 654 1.3E-232 T 21-04-2016 HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:3.40.50.300 555 645 8.4E-73 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04960 778aeff348f0dea0db7ef0598f318c73 769 Gene3D G3DSA:3.40.50.300 285 386 8.4E-73 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05020 e6cd6caff7ed6457555bea6eac8f6b5e 357 Pfam PF03787 RAMP superfamily 12 236 1.0E-19 T 21-04-2016 IPR005537 CRISPR type III-associated RAMP protein HSISS4_RS05020 e6cd6caff7ed6457555bea6eac8f6b5e 357 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 12 242 5.9E-29 T 21-04-2016 IPR010173 CRISPR-associated protein, TM1807 HSISS4_RS05020 e6cd6caff7ed6457555bea6eac8f6b5e 357 PANTHER PTHR38007 2 246 3.0E-23 T 21-04-2016 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 12 639 36.575 T 21-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 ProSitePatterns PS00674 AAA-protein family signature. 323 341 - T 21-04-2016 IPR003960 ATPase, AAA-type, conserved site GO:0005524 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 PANTHER PTHR23076 1 659 1.2E-296 T 21-04-2016 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 PANTHER PTHR23076:SF10 1 659 1.2E-296 T 21-04-2016 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 SUPERFAMILY SSF140990 435 626 4.84E-67 T 21-04-2016 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 134 621 6.7E-224 T 21-04-2016 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Pfam PF01434 Peptidase family M41 415 620 4.4E-78 T 21-04-2016 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Gene3D G3DSA:3.40.50.300 179 362 3.4E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Pfam PF06480 FtsH Extracellular 14 122 5.7E-8 T 21-04-2016 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 SUPERFAMILY SSF52540 177 423 6.0E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Gene3D G3DSA:1.10.8.60 363 427 6.6E-27 T 21-04-2016 HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 SMART SM00382 216 355 8.2E-24 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00065 4313504fd5681dffdd0883b32fa4a891 659 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 220 352 8.9E-44 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS05205 b908422b5fbbc04e190ef00406774397 143 PANTHER PTHR33221:SF5 1 142 1.2E-41 T 21-04-2016 HSISS4_RS05205 b908422b5fbbc04e190ef00406774397 143 PANTHER PTHR33221 1 142 1.2E-41 T 21-04-2016 HSISS4_RS05205 b908422b5fbbc04e190ef00406774397 143 Pfam PF02082 Transcriptional regulator 2 77 5.2E-21 T 21-04-2016 IPR000944 Transcription regulator Rrf2-type HSISS4_RS05205 b908422b5fbbc04e190ef00406774397 143 SUPERFAMILY SSF46785 2 134 6.4E-30 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05205 b908422b5fbbc04e190ef00406774397 143 Gene3D G3DSA:1.10.10.10 1 141 1.6E-46 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 Gene3D G3DSA:3.30.230.10 1 142 6.9E-44 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 SUPERFAMILY SSF54211 1 142 8.35E-31 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 77 88 - T 21-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 SUPERFAMILY SSF55060 153 267 4.73E-31 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 Gene3D G3DSA:3.30.70.890 149 273 1.7E-35 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 Pfam PF00288 GHMP kinases N terminal domain 71 131 2.9E-13 T 21-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 Hamap MF_00384 Homoserine kinase [thrB]. 1 285 31.246 T 21-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PANTHER PTHR20861:SF1 1 285 2.1E-84 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PANTHER PTHR20861 1 285 2.1E-84 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PIRSF PIRSF000676 1 286 2.0E-85 T 21-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 TIGRFAM TIGR00191 thrB: homoserine kinase 1 273 2.9E-70 T 21-04-2016 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702|UniPathway: UPA00050 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 Pfam PF08544 GHMP kinases C terminal 192 264 1.6E-6 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PRINTS PR00958 Homoserine kinase signature 8 23 1.0E-38 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PRINTS PR00958 Homoserine kinase signature 84 99 1.0E-38 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PRINTS PR00958 Homoserine kinase signature 156 173 1.0E-38 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PRINTS PR00958 Homoserine kinase signature 118 131 1.0E-38 T 21-04-2016 HSISS4_RS02195 4ffe10f5fa82af2ae5cd6cbea27fd295 286 PRINTS PR00958 Homoserine kinase signature 236 251 1.0E-38 T 21-04-2016 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 Gene3D G3DSA:3.30.160.20 212 285 2.1E-29 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 21-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 3 358 39.429 T 21-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 Gene3D G3DSA:1.20.58.410 4 95 4.3E-22 T 21-04-2016 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 PANTHER PTHR11075 2 357 9.6E-169 T 21-04-2016 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 SMART SM00937 65 180 2.6E-61 T 21-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 SUPERFAMILY SSF75620 10 354 1.57E-127 T 21-04-2016 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 Pfam PF00472 RF-1 domain 213 322 8.4E-38 T 21-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 Pfam PF03462 PCRF domain 11 205 4.0E-71 T 21-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 PANTHER PTHR11075:SF9 2 357 9.6E-169 T 21-04-2016 HSISS4_RS05800 fa7d6469c4a8f47eaa6a91fc75fe4e56 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 3 358 7.8E-159 T 21-04-2016 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 TIGRFAM TIGR00526 folB_dom: FolB domain 1 119 5.2E-28 T 21-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 SUPERFAMILY SSF55620 2 119 6.12E-40 T 21-04-2016 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 PANTHER PTHR20941 1 119 9.8E-34 T 21-04-2016 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 Pfam PF02152 Dihydroneopterin aldolase 4 116 2.9E-32 T 21-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 SMART SM00905 4 117 7.1E-51 T 21-04-2016 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 Gene3D G3DSA:3.30.1130.10 1 119 1.3E-42 T 21-04-2016 HSISS4_RS07365 0017a040ea01cc14d4526a4b524dbc2c 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 117 7.3E-38 T 21-04-2016 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 21-04-2016 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 Gene3D G3DSA:3.30.950.10 124 235 4.4E-39 T 21-04-2016 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 PANTHER PTHR21091 10 243 6.5E-88 T 21-04-2016 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 Gene3D G3DSA:1.10.10.60 245 288 6.8E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 16 286 4.4E-80 T 21-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 PANTHER PTHR21091:SF18 10 243 6.5E-88 T 21-04-2016 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 15 214 4.9E-21 T 21-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 35.713 T 21-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 SUPERFAMILY SSF53790 13 231 6.02E-80 T 21-04-2016 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 PIRSF PIRSF005917 4 288 1.7E-97 T 21-04-2016 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS02325 157837d92dae6ce0ac0bfdc4102c56eb 288 Gene3D G3DSA:3.40.1010.10 14 123 2.3E-13 T 21-04-2016 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 SUPERFAMILY SSF56235 12 239 5.23E-67 T 21-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 PIRSF PIRSF000485 8 473 1.0E-173 T 21-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 Pfam PF13522 Glutamine amidotransferase domain 74 206 4.9E-19 T 21-04-2016 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 458 1.2E-156 T 21-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 PANTHER PTHR11907 9 471 3.8E-234 T 21-04-2016 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 Pfam PF00156 Phosphoribosyl transferase domain 272 384 3.9E-10 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 SUPERFAMILY SSF53271 248 465 1.57E-74 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 Gene3D G3DSA:3.40.50.2020 270 435 2.2E-43 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 PANTHER PTHR11907:SF0 9 471 3.8E-234 T 21-04-2016 HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 Gene3D G3DSA:3.60.20.10 11 236 3.2E-65 T 21-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HSISS4_RS00225 36b4a49fd753f4476f2f7f0d4ac003e9 479 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 459 46.167 T 21-04-2016 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|UniPathway: UPA00074 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 SUPERFAMILY SSF81271 287 371 9.16E-36 T 21-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 371 44.19 T 21-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PANTHER PTHR23305 1 371 2.7E-205 T 21-04-2016 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PANTHER PTHR23305:SF12 1 371 2.7E-205 T 21-04-2016 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PIRSF PIRSF006641 1 371 1.7E-154 T 21-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Pfam PF01926 50S ribosome-binding GTPase 5 113 1.0E-23 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.3E-36 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 5.3E-36 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 5.3E-36 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 5.3E-36 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Pfam PF06071 Protein of unknown function (DUF933) 287 370 2.2E-40 T 21-04-2016 IPR013029 Domain of unknown function DUF933 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 SUPERFAMILY SSF52540 3 309 4.53E-84 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Gene3D G3DSA:1.10.150.300 135 205 9.1E-30 T 21-04-2016 IPR023192 TGS-like domain HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 371 5.8E-149 T 21-04-2016 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Gene3D G3DSA:3.40.50.300 206 274 8.4E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Gene3D G3DSA:3.40.50.300 4 134 8.4E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00020 d51b4dbc08dec7b5205926af1796dbb9 371 Gene3D G3DSA:3.10.20.30 275 371 6.4E-50 T 21-04-2016 IPR012675 Beta-grasp domain HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 1.4E-39 T 21-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 SUPERFAMILY SSF102735 1 128 4.97E-33 T 21-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 421 1.8E-44 T 21-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 PANTHER PTHR30560 1 427 2.3E-115 T 21-04-2016 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 PANTHER PTHR30560:SF3 1 427 2.3E-115 T 21-04-2016 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Hamap MF_00303 Trigger factor [tig]. 1 427 22.07 T 21-04-2016 IPR005215 Trigger factor GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Gene3D G3DSA:1.10.3120.10 217 399 2.4E-57 T 21-04-2016 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Gene3D G3DSA:3.10.50.40 159 216 2.4E-11 T 21-04-2016 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 TIGRFAM TIGR00115 tig: trigger factor 13 420 1.0E-126 T 21-04-2016 IPR005215 Trigger factor GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 SUPERFAMILY SSF109998 250 427 3.27E-38 T 21-04-2016 IPR027304 Trigger factor/SurA domain HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Gene3D G3DSA:3.30.70.1050 1 119 1.1E-34 T 21-04-2016 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 PIRSF PIRSF003095 1 427 8.7E-122 T 21-04-2016 IPR005215 Trigger factor GO:0015031 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 SUPERFAMILY SSF54534 89 243 8.64E-37 T 21-04-2016 HSISS4_RS00735 97492c744941f1d63ab38ea9bc3c123c 427 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 159 231 1.5E-14 T 21-04-2016 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain GO:0006457 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 Gene3D G3DSA:3.30.300.20 189 289 2.5E-42 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 SUPERFAMILY SSF54814 179 295 6.54E-43 T 21-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 Gene3D G3DSA:3.40.50.300 7 188 7.4E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 Hamap MF_00367 GTPase Era [era]. 3 294 38.103 T 21-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 165 8.2E-33 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 Pfam PF07650 KH domain 205 283 1.9E-24 T 21-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 6 277 2.3E-106 T 21-04-2016 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 PANTHER PTHR11649:SF3 4 299 5.9E-124 T 21-04-2016 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 Pfam PF01926 50S ribosome-binding GTPase 8 122 2.6E-24 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 PANTHER PTHR11649 4 299 5.9E-124 T 21-04-2016 HSISS4_RS02915 02276ea3dfcedac88105bcb9916e5cae 299 SUPERFAMILY SSF52540 8 202 4.83E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01555 cc29bebf3642f6ccf928183a1e397386 100 Gene3D G3DSA:3.30.1330.30 3 97 4.4E-22 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS01555 cc29bebf3642f6ccf928183a1e397386 100 SUPERFAMILY SSF55315 5 99 3.44E-25 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS01555 cc29bebf3642f6ccf928183a1e397386 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 6 95 3.4E-15 T 21-04-2016 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Gene3D G3DSA:2.60.40.740 329 433 6.6E-13 T 21-04-2016 IPR008456 Collagen binding domain GO:0005518 HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 SUPERFAMILY SSF49401 177 288 2.11E-14 T 21-04-2016 IPR008966 Adhesion domain HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF04650 YSIRK type signal peptide 9 32 4.7E-10 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 SUPERFAMILY SSF49401 316 435 3.23E-15 T 21-04-2016 IPR008966 Adhesion domain HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 509 573 2.5E-12 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 627 688 2.3E-15 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 853 918 5.2E-13 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 741 802 3.8E-15 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF05737 Collagen binding domain 317 419 2.0E-9 T 21-04-2016 IPR008456 Collagen binding domain GO:0005518 HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 40 2.3E-12 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 971 1006 9.9E-4 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF12892 T surface-antigen of pili 520 608 2.0E-8 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF12892 T surface-antigen of pili 752 834 2.5E-13 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF12892 T surface-antigen of pili 864 901 1.9E-5 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Pfam PF12892 T surface-antigen of pili 638 722 6.2E-9 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS02655 e93469e450e5705874eb7360012ef914 1008 Gene3D G3DSA:2.60.40.1280 170 328 1.3E-16 T 21-04-2016 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 SUPERFAMILY SSF55174 1 87 3.53E-14 T 21-04-2016 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 SMART SM00363 1 66 7.8E-8 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 21-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 229 1.0E-48 T 21-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 Pfam PF00849 RNA pseudouridylate synthase 62 197 4.9E-21 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 PANTHER PTHR21600 1 235 3.5E-67 T 21-04-2016 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 Gene3D G3DSA:3.10.290.10 1 64 1.4E-19 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 Pfam PF01479 S4 domain 1 44 3.1E-9 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 PANTHER PTHR21600:SF19 1 235 3.5E-67 T 21-04-2016 HSISS4_RS07225 5dcabb31039d72421fbdbb49fb8ff979 243 SUPERFAMILY SSF55120 62 232 1.12E-42 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 PANTHER PTHR34385:SF1 514 734 7.7E-53 T 21-04-2016 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 41 1.3E-13 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 736 797 1.1E-21 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 905 967 5.9E-22 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 352 414 5.9E-22 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 260 321 9.1E-15 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 165 227 2.1E-25 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 820 882 3.8E-22 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08460 Bacterial SH3 domain 983 1045 2.7E-22 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 261 328 2.9 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 355 421 9.3E-11 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 168 234 0.0024 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 823 889 0.0027 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 736 804 7.6E-4 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 984 1046 0.97 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SMART SM00287 908 974 0.018 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 572 693 2.7E-33 T 21-04-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 PANTHER PTHR34385 514 734 7.7E-53 T 21-04-2016 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF04650 YSIRK type signal peptide 10 33 4.6E-11 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 SUPERFAMILY SSF55166 572 695 2.2E-27 T 21-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HSISS4_RS02150 726570a19814707c830ba3c0470c101d 1046 Pfam PF08481 GBS Bsp-like repeat 434 522 3.6E-27 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS08875 5c74b1a381d59154839d2e7d094a819a 155 Pfam PF00857 Isochorismatase family 5 135 5.8E-15 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS08875 5c74b1a381d59154839d2e7d094a819a 155 Gene3D G3DSA:3.40.50.850 5 150 3.7E-17 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS08875 5c74b1a381d59154839d2e7d094a819a 155 SUPERFAMILY SSF52499 5 150 1.22E-20 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 PANTHER PTHR22777:SF8 2 443 3.3E-173 T 21-04-2016 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 SUPERFAMILY SSF56176 353 434 2.26E-17 T 21-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Pfam PF01595 Domain of unknown function DUF21 14 200 8.4E-46 T 21-04-2016 IPR002550 Domain of unknown function DUF21 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 PANTHER PTHR22777 2 443 3.3E-173 T 21-04-2016 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 SUPERFAMILY SSF54631 203 340 3.28E-30 T 21-04-2016 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Pfam PF03471 Transporter associated domain 353 433 4.6E-16 T 21-04-2016 IPR005170 Transporter-associated domain HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Gene3D G3DSA:3.30.465.10 351 434 9.0E-23 T 21-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Gene3D G3DSA:3.10.580.10 203 350 7.4E-19 T 21-04-2016 HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Pfam PF00571 CBS domain 285 337 4.0E-5 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 Pfam PF00571 CBS domain 222 272 4.8E-4 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07940 a66ea7cffcf62a1a0a9cd6bfa6d30bb4 443 SMART SM01091 352 436 1.7E-15 T 21-04-2016 IPR005170 Transporter-associated domain HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 PANTHER PTHR10245 7 66 2.0E-20 T 21-04-2016 HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 SMART SM00530 10 65 7.8E-17 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 Pfam PF01381 Helix-turn-helix 11 65 1.8E-17 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 PANTHER PTHR10245:SF61 7 66 2.0E-20 T 21-04-2016 HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 SUPERFAMILY SSF47413 7 67 2.2E-19 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS00620 fbfb35dd4f5055a3caf883e837d25f00 69 Gene3D G3DSA:1.10.260.40 7 67 1.9E-25 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 33 122 2.3E-7 T 21-04-2016 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 Gene3D G3DSA:1.10.150.130 32 123 1.7E-12 T 21-04-2016 IPR023109 Integrase/recombinase, N-terminal HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 Pfam PF00589 Phage integrase family 183 344 5.8E-25 T 21-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 Gene3D G3DSA:1.10.443.10 169 353 1.1E-38 T 21-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 Hamap MF_01816 Tyrosine recombinase XerS [xerS]. 1 356 59.789 T 21-04-2016 IPR023670 Tyrosine recombinase XerS GO:0006310|GO:0007049|GO:0007059|GO:0015074|GO:0051301 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 SUPERFAMILY SSF56349 20 353 4.71E-35 T 21-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 PANTHER PTHR30349 188 355 2.3E-105 T 21-04-2016 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 PANTHER PTHR30349 11 159 2.3E-105 T 21-04-2016 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 PANTHER PTHR30349:SF17 188 355 2.3E-105 T 21-04-2016 HSISS4_RS04860 07638d5eb645b415c37b91047ae60867 356 PANTHER PTHR30349:SF17 11 159 2.3E-105 T 21-04-2016 HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 PANTHER PTHR35794:SF1 1 110 1.1E-37 T 21-04-2016 HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 1 106 23.999 T 21-04-2016 IPR011229 Cell cycle protein GpsB HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 6 39 4.3E-16 T 21-04-2016 IPR019933 DivIVA domain HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 PANTHER PTHR35794 1 110 1.1E-37 T 21-04-2016 HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 Pfam PF05103 DivIVA protein 6 65 5.6E-16 T 21-04-2016 IPR007793 DivIVA family HSISS4_RS01125 5aab7d6814e07e4c528d47040164483b 110 PIRSF PIRSF029938 1 110 5.9E-41 T 21-04-2016 IPR011229 Cell cycle protein GpsB HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 Pfam PF00654 Voltage gated chloride channel 71 416 3.7E-84 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PANTHER PTHR11689:SF96 1 432 3.2E-72 T 21-04-2016 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 SUPERFAMILY SSF116726 445 510 3.79E-6 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 SUPERFAMILY SSF81340 7 432 2.62E-101 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 Pfam PF02080 TrkA-C domain 448 510 3.5E-7 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PRINTS PR00762 Chloride channel signature 384 403 2.3E-22 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PRINTS PR00762 Chloride channel signature 83 100 2.3E-22 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PRINTS PR00762 Chloride channel signature 163 182 2.3E-22 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PRINTS PR00762 Chloride channel signature 366 382 2.3E-22 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PRINTS PR00762 Chloride channel signature 331 351 2.3E-22 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 Gene3D G3DSA:1.10.3080.10 6 429 3.3E-83 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS04210 333ade49d83eabcde92cc7e286c2f4a7 511 PANTHER PTHR11689 1 432 3.2E-72 T 21-04-2016 HSISS4_RS00850 fb397b9cea7c0d4e59b213afbdffc3e8 249 PIRSF PIRSF029008 1 249 2.7E-74 T 21-04-2016 IPR008681 Negative regulator of genetic competence, MecA HSISS4_RS00850 fb397b9cea7c0d4e59b213afbdffc3e8 249 PANTHER PTHR39161 2 244 1.3E-55 T 21-04-2016 HSISS4_RS00850 fb397b9cea7c0d4e59b213afbdffc3e8 249 PANTHER PTHR39161:SF1 2 244 1.3E-55 T 21-04-2016 HSISS4_RS00850 fb397b9cea7c0d4e59b213afbdffc3e8 249 Hamap MF_01124 Adapter protein MecA [mecA]. 1 247 24.117 T 21-04-2016 IPR008681 Negative regulator of genetic competence, MecA HSISS4_RS00850 fb397b9cea7c0d4e59b213afbdffc3e8 249 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 242 1.5E-43 T 21-04-2016 IPR008681 Negative regulator of genetic competence, MecA HSISS4_RS09705 82b30395359a9db2c7d11d34dff07e07 290 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 7 210 7.6E-60 T 21-04-2016 IPR003740 Uncharacterised membrane protein YitT HSISS4_RS09705 82b30395359a9db2c7d11d34dff07e07 290 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 216 270 3.2E-14 T 21-04-2016 IPR019264 Domain of unknown function DUF2179 HSISS4_RS09705 82b30395359a9db2c7d11d34dff07e07 290 PANTHER PTHR33545 1 279 9.6E-77 T 21-04-2016 HSISS4_RS09705 82b30395359a9db2c7d11d34dff07e07 290 PIRSF PIRSF006483 1 277 2.8E-75 T 21-04-2016 IPR003740 Uncharacterised membrane protein YitT HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Pfam PF03193 Protein of unknown function, DUF258 59 215 3.6E-58 T 21-04-2016 IPR010914 RsgA type GTPase domain GO:0003924|GO:0005525 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Pfam PF16745 RsgA N-terminal domain 2 55 6.3E-25 T 21-04-2016 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 1 280 38.312 T 21-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 PANTHER PTHR32120 2 290 8.9E-116 T 21-04-2016 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 SUPERFAMILY SSF50249 2 61 2.0E-14 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Gene3D G3DSA:1.10.40.50 219 288 1.4E-26 T 21-04-2016 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Gene3D G3DSA:2.40.50.140 2 58 8.3E-27 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 PANTHER PTHR32120:SF2 2 290 8.9E-116 T 21-04-2016 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 Gene3D G3DSA:3.40.50.300 62 214 1.1E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 273 6.3E-76 T 21-04-2016 IPR004881 Ribosome biogenesis GTPase RsgA, putative GO:0003924|GO:0005525 HSISS4_RS08625 dbc9b2191a6952ee1876682099433d46 290 SUPERFAMILY SSF52540 64 280 2.79E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 SMART SM00116 23 71 10.0 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 SMART SM00116 92 138 0.034 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 SUPERFAMILY SSF54631 15 138 4.55E-24 T 21-04-2016 HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 PANTHER PTHR11911:SF103 22 151 2.5E-27 T 21-04-2016 HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 Gene3D G3DSA:3.10.580.10 8 146 6.1E-26 T 21-04-2016 HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 Pfam PF00571 CBS domain 34 70 5.1E-5 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 Pfam PF00571 CBS domain 84 137 8.5E-8 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01235 5c76b39207f1d6a91f90374df9623c35 160 PANTHER PTHR11911 22 151 2.5E-27 T 21-04-2016 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 SUPERFAMILY SSF54849 136 204 7.55E-26 T 21-04-2016 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 40.752 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 521 8.2E-104 T 21-04-2016 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PRINTS PR00298 60kDa chaperonin signature 82 109 2.9E-73 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PRINTS PR00298 60kDa chaperonin signature 396 417 2.9E-73 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PRINTS PR00298 60kDa chaperonin signature 26 52 2.9E-73 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PRINTS PR00298 60kDa chaperonin signature 266 289 2.9E-73 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PRINTS PR00298 60kDa chaperonin signature 348 373 2.9E-73 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 Gene3D G3DSA:3.50.7.10 197 333 1.1E-70 T 21-04-2016 IPR027409 GroEL-like apical domain HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 Gene3D G3DSA:1.10.560.10 344 515 2.9E-43 T 21-04-2016 IPR027413 GroEL-like equatorial domain HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 SUPERFAMILY SSF52029 182 374 5.23E-84 T 21-04-2016 IPR027409 GroEL-like apical domain HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 PANTHER PTHR11353 1 538 1.4E-233 T 21-04-2016 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 21-04-2016 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 523 1.3E-251 T 21-04-2016 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 Gene3D G3DSA:1.10.560.10 3 196 2.5E-49 T 21-04-2016 IPR027413 GroEL-like equatorial domain HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 SUPERFAMILY SSF48592 6 133 5.5E-79 T 21-04-2016 HSISS4_RS00990 3bcd24e0d3d1ca4cfb4e0c22d707adc4 539 SUPERFAMILY SSF48592 404 518 5.5E-79 T 21-04-2016 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 Pfam PF01174 SNO glutamine amidotransferase family 6 190 1.3E-57 T 21-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 187 3.3E-74 T 21-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 188 35.685 T 21-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 PANTHER PTHR31559:SF0 1 197 1.5E-81 T 21-04-2016 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 SUPERFAMILY SSF52317 3 190 4.73E-49 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 PANTHER PTHR31559 1 197 1.5E-81 T 21-04-2016 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 Gene3D G3DSA:3.40.50.880 2 194 1.4E-72 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 PIRSF PIRSF005639 1 193 6.5E-69 T 21-04-2016 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06570 77cf9c27509308d6ab7038a888393216 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 44 54 - T 21-04-2016 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 Pfam PF00107 Zinc-binding dehydrogenase 180 305 3.8E-23 T 21-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 PANTHER PTHR11695:SF38 15 347 2.7E-109 T 21-04-2016 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 136 5.4E-24 T 21-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 71 85 - T 21-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 PANTHER PTHR11695 15 347 2.7E-109 T 21-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 SMART SM00829 10 344 1.1E-4 T 21-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 Gene3D G3DSA:3.40.50.720 172 291 1.6E-36 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 SUPERFAMILY SSF50129 3 179 5.48E-48 T 21-04-2016 IPR011032 GroES-like HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 SUPERFAMILY SSF51735 144 310 2.35E-36 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07850 645fa20dc29b538cf944d5efc36645af 347 Gene3D G3DSA:3.90.180.10 2 171 1.1E-51 T 21-04-2016 IPR011032 GroES-like HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 6 101 2.2E-21 T 21-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 4 116 9.7E-26 T 21-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 116 21.896 T 21-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 SUPERFAMILY SSF56214 1 116 1.22E-34 T 21-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 Gene3D G3DSA:3.90.470.20 1 116 1.8E-36 T 21-04-2016 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 115 3.0E-56 T 21-04-2016 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS08320 7a52dc8d033187313d4ca8d5ea4b036f 117 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 116 6.1E-23 T 21-04-2016 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1 HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 SMART SM00855 5 181 6.2E-20 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 Gene3D G3DSA:3.40.50.1240 1 231 7.2E-51 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 SUPERFAMILY SSF53254 1 220 1.94E-49 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 216 5.2E-32 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 PANTHER PTHR23029:SF29 6 228 1.0E-75 T 21-04-2016 HSISS4_RS00650 6d661f7b605a06897492286e32f3cba5 234 PANTHER PTHR23029 6 228 1.0E-75 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 186 197 - T 21-04-2016 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 SUPERFAMILY SSF47831 24 145 1.15E-35 T 21-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PANTHER PTHR22931 13 29 1.3E-201 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PANTHER PTHR22931 50 554 1.3E-201 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 SUPERFAMILY SSF52009 127 245 1.29E-35 T 21-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 468 483 3.1E-32 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 451 466 3.1E-32 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 295 314 3.1E-32 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 504 516 3.1E-32 T 21-04-2016 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 451 469 - T 21-04-2016 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 SUPERFAMILY SSF51621 251 553 2.62E-109 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Gene3D G3DSA:1.10.274.10 24 134 3.1E-41 T 21-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 128 2.3E-32 T 21-04-2016 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 252 545 2.3E-129 T 21-04-2016 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 PIRSF PIRSF000732 1 577 2.4E-212 T 21-04-2016 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 569 8.6E-229 T 21-04-2016 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Gene3D G3DSA:3.50.30.10 135 258 4.3E-43 T 21-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Pfam PF00391 PEP-utilising enzyme, mobile domain 154 227 1.8E-21 T 21-04-2016 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 HSISS4_RS03710 444e70481221b60db14cace37e67e8e9 577 Gene3D G3DSA:3.20.20.60 259 574 7.5E-113 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS06215 c987618874c4699ca45a33e596bf4f84 65 Pfam PF05532 CsbD-like 3 52 7.3E-14 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS06215 c987618874c4699ca45a33e596bf4f84 65 Gene3D G3DSA:1.10.1470.10 3 63 2.3E-18 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS06215 c987618874c4699ca45a33e596bf4f84 65 SUPERFAMILY SSF69047 3 59 2.09E-10 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 6.4E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 660 720 3.3E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 726 782 3.1E-13 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 572 631 2.9E-26 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 258 318 3.5E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 162 223 5.1E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 415 439 5.5E-5 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 471 518 5.5E-5 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 343 414 3.2E-13 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 695 743 5.3E-12 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.20.120.10 306 342 1.3E-9 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.20.120.10 230 269 2.2E-6 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.20.120.10 540 584 4.3E-8 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.20.120.10 654 694 6.2E-9 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 156 202 5.4E-31 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 258 384 5.4E-31 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 569 625 5.4E-31 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 400 445 3.34E-5 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 159 229 1.9E-18 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 585 648 2.8E-18 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 270 305 7.7E-17 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 819 927 4.32E-8 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 744 837 1.2E-21 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Gene3D G3DSA:2.10.270.10 841 928 2.3E-6 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 SUPERFAMILY SSF69360 653 833 6.91E-36 T 21-04-2016 HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Pfam PF01473 Putative cell wall binding repeat 761 773 0.12 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Pfam PF01473 Putative cell wall binding repeat 160 169 0.011 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Pfam PF01473 Putative cell wall binding repeat 293 309 0.027 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06580 82406b25559fc8c45ce3877d770fc614 932 Pfam PF01473 Putative cell wall binding repeat 797 812 0.056 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 9.0E-9 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 PANTHER PTHR33498 1 414 7.1E-105 T 21-04-2016 HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 Pfam PF01610 Transposase 157 400 4.0E-47 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 SUPERFAMILY SSF46689 99 142 1.84E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 2.7E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 PANTHER PTHR33498:SF1 1 414 7.1E-105 T 21-04-2016 HSISS4_RS03365 63c026dd4ca612496b075c7dafb6d10c 418 Gene3D G3DSA:1.10.10.60 106 139 2.5E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 PIRSF PIRSF004749 2 136 3.5E-30 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 PANTHER PTHR10458 26 136 1.8E-25 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 Gene3D G3DSA:3.90.45.10 10 135 4.0E-34 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 SUPERFAMILY SSF56420 8 136 2.88E-34 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 Pfam PF01327 Polypeptide deformylase 14 136 2.4E-23 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 PRINTS PR01576 Peptide deformylase signature 83 94 1.3E-12 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 PRINTS PR01576 Peptide deformylase signature 30 59 1.3E-12 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS01975 77126e7c9d444015f90633a0c7f61c98 136 PRINTS PR01576 Peptide deformylase signature 113 136 1.3E-12 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 301 314 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 323 339 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 202 223 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 376 388 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 4 15 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PRINTS PR00471 Acetate kinase family signature 172 185 4.0E-42 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PANTHER PTHR21060 1 394 6.1E-199 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PANTHER PTHR21060:SF11 1 394 6.1E-199 T 21-04-2016 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 SUPERFAMILY SSF53067 155 394 6.26E-84 T 21-04-2016 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 21-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 21-04-2016 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 181.447 T 21-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 Pfam PF00871 Acetokinase family 4 389 1.7E-145 T 21-04-2016 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 Gene3D G3DSA:3.30.420.40 204 394 3.5E-74 T 21-04-2016 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 SUPERFAMILY SSF53067 1 195 9.5E-66 T 21-04-2016 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 Gene3D G3DSA:3.30.420.40 3 203 2.1E-9 T 21-04-2016 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 3.6E-150 T 21-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS09035 526aedb512612adfdae0252c5f7fadbb 397 PIRSF PIRSF000722 1 397 1.9E-145 T 21-04-2016 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|UniPathway: UPA00340 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 PANTHER PTHR10046 219 306 7.2E-38 T 21-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 SUPERFAMILY SSF54211 168 354 2.31E-23 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 PANTHER PTHR10046:SF48 219 306 7.2E-38 T 21-04-2016 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 SUPERFAMILY SSF50156 112 198 8.06E-5 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 Pfam PF13180 PDZ domain 142 206 9.2E-10 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 Gene3D G3DSA:3.30.230.10 242 354 1.4E-20 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 PANTHER PTHR10046 322 357 7.2E-38 T 21-04-2016 IPR027065 Lon protease GO:0004176|GO:0004252|GO:0005524|GO:0030163 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 PANTHER PTHR10046:SF48 322 357 7.2E-38 T 21-04-2016 HSISS4_RS07975 7820c1ccf67ca5bc190d353b69f88f94 358 Gene3D G3DSA:2.30.42.10 143 209 1.6E-10 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 PANTHER PTHR30614 276 732 2.7E-227 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 25 113 7.4E-37 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 456 498 3.4E-40 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 206 248 7.4E-37 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 275 354 3.4E-40 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 547 732 5.1E-24 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SUPERFAMILY SSF53850 1 248 2.74E-61 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SMART SM00062 27 249 7.2E-51 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SMART SM00062 277 498 8.8E-56 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 114 203 2.0E-24 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SUPERFAMILY SSF53850 276 496 4.29E-64 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SUPERFAMILY SSF161098 524 717 7.06E-46 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 PANTHER PTHR30614:SF0 276 732 2.7E-227 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:1.10.3720.10 517 732 1.1E-68 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Gene3D G3DSA:3.40.190.10 355 445 1.4E-26 T 21-04-2016 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 SMART SM00079 27 248 1.5E-4 T 21-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 247 1.3E-57 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 279 496 4.9E-58 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07205 81a1a5d3bdde6d1c85e60b5b0890d8f8 732 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 522 626 1.8E-23 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 PANTHER PTHR11562 4 283 4.5E-65 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 Pfam PF01545 Cation efflux family 8 195 9.5E-37 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 Gene3D G3DSA:1.20.1510.10 4 195 1.6E-43 T 21-04-2016 IPR027469 Cation efflux protein transmembrane domain HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 PANTHER PTHR11562:SF17 4 283 4.5E-65 T 21-04-2016 HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 SUPERFAMILY SSF161111 4 197 1.1E-41 T 21-04-2016 HSISS4_RS05160 343f2c676c3a3ac5f8fab23ed911af81 303 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 5 273 7.0E-53 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS01510 75f098b158345dc9f4e43d381cf3c519 245 SUPERFAMILY SSF102198 14 242 1.44E-54 T 21-04-2016 HSISS4_RS01510 75f098b158345dc9f4e43d381cf3c519 245 Pfam PF04199 Putative cyclase 17 182 2.0E-31 T 21-04-2016 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|UniPathway: UPA00333 HSISS4_RS01510 75f098b158345dc9f4e43d381cf3c519 245 Gene3D G3DSA:3.50.30.50 14 242 3.6E-60 T 21-04-2016 HSISS4_RS01510 75f098b158345dc9f4e43d381cf3c519 245 PANTHER PTHR31118:SF9 11 243 7.6E-56 T 21-04-2016 HSISS4_RS01510 75f098b158345dc9f4e43d381cf3c519 245 PANTHER PTHR31118 11 243 7.6E-56 T 21-04-2016 HSISS4_RS05300 78829f6ba113823f75784e40a844d24d 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 86 1.0E-10 T 21-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HSISS4_RS05300 78829f6ba113823f75784e40a844d24d 143 Gene3D G3DSA:2.30.110.10 4 143 3.4E-33 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS05300 78829f6ba113823f75784e40a844d24d 143 SUPERFAMILY SSF50475 7 121 7.5E-16 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 SUPERFAMILY SSF116842 4 69 6.02E-18 T 21-04-2016 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 6 66 14.132 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 PANTHER PTHR34137 1 70 5.0E-20 T 21-04-2016 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 Gene3D G3DSA:1.10.287.1040 3 69 1.5E-22 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 PIRSF PIRSF006488 1 71 1.6E-18 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 Pfam PF02609 Exonuclease VII small subunit 7 56 4.4E-18 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 1 48 2.0E-19 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04060 eb805201ebfae0d5df205cfd3e682ca2 71 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 61 9.7E-22 T 21-04-2016 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PANTHER PTHR34471 1 148 1.1E-32 T 21-04-2016 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 Gene3D G3DSA:3.30.1360.40 80 145 5.2E-9 T 21-04-2016 IPR024946 Arginine repressor C-terminal-like domain HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PANTHER PTHR34471:SF1 1 148 1.1E-32 T 21-04-2016 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 Hamap MF_00173 Arginine repressor [argR]. 1 148 43.137 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 Pfam PF02863 Arginine repressor, C-terminal domain 81 142 4.0E-7 T 21-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PRINTS PR01467 Bacterial arginine repressor signature 37 52 3.3E-15 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PRINTS PR01467 Bacterial arginine repressor signature 115 130 3.3E-15 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PRINTS PR01467 Bacterial arginine repressor signature 85 98 3.3E-15 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 PRINTS PR01467 Bacterial arginine repressor signature 21 34 3.3E-15 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 SUPERFAMILY SSF46785 1 66 3.86E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 Gene3D G3DSA:1.10.10.10 9 65 2.3E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 Pfam PF01316 Arginine repressor, DNA binding domain 1 65 4.1E-25 T 21-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 HSISS4_RS04075 419e85faa96da0ad7361e7800bfae57e 148 SUPERFAMILY SSF55252 80 145 2.49E-12 T 21-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 SMART SM00418 5 79 4.3E-22 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 SUPERFAMILY SSF46785 3 83 4.47E-26 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 Gene3D G3DSA:1.10.10.10 3 89 2.4E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 Pfam PF01022 Bacterial regulatory protein, arsR family 13 57 3.1E-16 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 PANTHER PTHR33154 3 84 3.8E-22 T 21-04-2016 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 4.9E-11 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 4.9E-11 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS06490 76a0a16f5dafb7d43dc71099c4fc37bc 91 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 4.9E-11 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 269 1.0E-125 T 21-04-2016 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 Pfam PF00156 Phosphoribosyl transferase domain 107 263 4.2E-26 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 PANTHER PTHR11776 48 263 2.9E-114 T 21-04-2016 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 10 73 6.0E-29 T 21-04-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 PANTHER PTHR11776:SF9 48 263 2.9E-114 T 21-04-2016 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 8.6E-30 T 21-04-2016 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 Gene3D G3DSA:3.40.50.2020 83 264 7.9E-55 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 SUPERFAMILY SSF46785 2 73 9.25E-25 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 SUPERFAMILY SSF53271 85 236 6.82E-36 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS08600 a559f769afd6351d763895adbf8b7e3f 271 Gene3D G3DSA:1.10.10.10 1 73 1.0E-36 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 Gene3D G3DSA:1.10.10.10 84 158 3.8E-33 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 Pfam PF04079 Segregation and condensation complex subunit ScpB 7 165 3.7E-52 T 21-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 SUPERFAMILY SSF46785 3 79 1.49E-13 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 Hamap MF_01804 Segregation and condensation protein B [scpB]. 1 180 32.878 T 21-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 PANTHER PTHR34298:SF2 5 192 2.8E-50 T 21-04-2016 HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 PANTHER PTHR34298 5 192 2.8E-50 T 21-04-2016 HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 Gene3D G3DSA:1.10.10.10 5 79 7.3E-16 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 SUPERFAMILY SSF46785 84 158 1.95E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 PIRSF PIRSF019345 1 193 9.9E-49 T 21-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HSISS4_RS01250 560df9560e5791bd5404836da1cd59c3 193 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 6 180 4.8E-44 T 21-04-2016 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 121 129 - T 21-04-2016 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 Gene3D G3DSA:3.30.70.141 5 141 3.0E-54 T 21-04-2016 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 Pfam PF00334 Nucleoside diphosphate kinase 7 141 5.0E-49 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 9.1E-30 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 9.1E-30 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 121 140 9.1E-30 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 9.1E-30 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 SUPERFAMILY SSF54919 6 141 1.7E-52 T 21-04-2016 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 PANTHER PTHR11349 5 142 4.4E-63 T 21-04-2016 HSISS4_RS05340 9a1d16a80e1992dbb3c9e5ed55c6805e 142 SMART SM00562 6 142 2.9E-56 T 21-04-2016 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 Pfam PF01610 Transposase 157 400 5.0E-47 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 2.7E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 PANTHER PTHR33498 1 414 3.5E-105 T 21-04-2016 HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 SUPERFAMILY SSF46689 99 142 1.84E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 PANTHER PTHR33498:SF1 1 414 3.5E-105 T 21-04-2016 HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 Gene3D G3DSA:1.10.10.60 106 139 2.5E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS07950 f96536fc6c5a756b4ef230849f35a94e 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 9.0E-9 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 PANTHER PTHR11911 188 301 1.1E-14 T 21-04-2016 HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SUPERFAMILY SSF75138 71 183 1.57E-29 T 21-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SUPERFAMILY SSF54637 324 421 7.02E-8 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SUPERFAMILY SSF46785 6 59 1.25E-6 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Gene3D G3DSA:3.40.1390.20 67 184 3.4E-43 T 21-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 58 9.4E-5 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SUPERFAMILY SSF54631 184 310 1.64E-24 T 21-04-2016 HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Gene3D G3DSA:1.10.10.10 13 58 1.5E-8 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SMART SM00116 199 247 0.075 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 SMART SM00116 257 305 0.07 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Gene3D G3DSA:3.10.129.10 323 419 1.8E-7 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Gene3D G3DSA:3.10.580.10 185 308 1.6E-23 T 21-04-2016 HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Pfam PF00571 CBS domain 252 305 5.4E-7 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Pfam PF00571 CBS domain 202 242 1.4E-5 T 21-04-2016 IPR000644 CBS domain HSISS4_RS07495 d06931e59aafa16d555ed8342cde7594 426 Pfam PF07085 DRTGG domain 75 177 8.4E-33 T 21-04-2016 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 Gene3D G3DSA:3.10.129.10 1 126 6.1E-38 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 SUPERFAMILY SSF54637 2 125 1.84E-31 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 Pfam PF13279 Thioesterase-like superfamily 11 116 6.7E-12 T 21-04-2016 HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 PIRSF PIRSF003230 1 134 4.3E-29 T 21-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 PANTHER PTHR31793 1 115 2.5E-31 T 21-04-2016 HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 PANTHER PTHR31793:SF9 1 115 2.5E-31 T 21-04-2016 HSISS4_RS08665 249daf210beeb815da72ec175f989013 137 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 7 113 1.7E-23 T 21-04-2016 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 HSISS4_RS01405 b349ee51f1cadefceeb5932a61bb70de 276 PANTHER PTHR33514:SF1 6 266 5.6E-98 T 21-04-2016 HSISS4_RS01405 b349ee51f1cadefceeb5932a61bb70de 276 PANTHER PTHR33514 6 266 5.6E-98 T 21-04-2016 HSISS4_RS01405 b349ee51f1cadefceeb5932a61bb70de 276 Pfam PF02361 Cobalt transport protein 18 230 1.5E-27 T 21-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF01473 Putative cell wall binding repeat 1309 1328 0.0033 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF01473 Putative cell wall binding repeat 1374 1391 6.6E-4 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF01473 Putative cell wall binding repeat 1330 1346 0.21 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF01473 Putative cell wall binding repeat 1176 1195 7.9E-5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF01473 Putative cell wall binding repeat 1496 1514 4.5E-4 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF69360 1177 1432 3.92E-42 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:3.20.20.80 312 350 1.5E-25 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:3.20.20.80 689 755 1.5E-25 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:3.20.20.80 486 655 1.5E-25 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF69360 1354 1559 3.53E-44 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Pfam PF02324 Glycosyl hydrolase family 70 360 1158 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF51445 476 666 4.22E-33 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1154 1232 5.8E-15 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1507 1559 4.8E-12 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1427 1506 5.5E-20 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1267 1323 1.2E-9 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1324 1386 1.8E-20 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1387 1426 8.8E-9 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF51445 703 750 4.22E-33 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 251 294 6.8E-6 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:2.10.270.10 1233 1266 7.9E-6 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF69360 254 293 1.7E-5 T 21-04-2016 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1506 1561 1.0E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1186 1245 4.2E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1319 1380 1.0E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1382 1440 1.1E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1442 1504 1.6E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1254 1315 1.7E-14 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 1.3E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 SUPERFAMILY SSF51445 918 1065 7.04E-24 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06520 fd20d58873f430f3e4ab71794c741aaf 1561 Gene3D G3DSA:3.20.20.80 938 1026 2.0E-17 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Gene3D G3DSA:1.10.150.20 539 591 3.5E-19 T 21-04-2016 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 PANTHER PTHR30562 2 590 2.5E-256 T 21-04-2016 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 PANTHER PTHR30562:SF1 2 590 2.5E-256 T 21-04-2016 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Pfam PF01541 GIY-YIG catalytic domain 16 88 1.5E-7 T 21-04-2016 IPR000305 GIY-YIG nuclease superfamily HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Gene3D G3DSA:3.40.1440.10 15 91 3.0E-8 T 21-04-2016 IPR027299 GIY-YIG domain HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Pfam PF02151 UvrB/uvrC motif 196 229 3.1E-8 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Gene3D G3DSA:4.10.860.10 182 235 4.3E-13 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Pfam PF14520 Helix-hairpin-helix domain 540 592 9.7E-7 T 21-04-2016 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 SUPERFAMILY SSF47781 504 592 1.14E-20 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 6 572 5.3E-194 T 21-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 589 27.332 T 21-04-2016 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 SUPERFAMILY SSF46600 183 235 3.01E-11 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 379 525 1.5E-49 T 21-04-2016 IPR001162 UvrC family homology region HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 SMART SM00465 15 95 1.9E-20 T 21-04-2016 IPR000305 GIY-YIG nuclease superfamily HSISS4_RS05985 2f6155f8daaffd192752f57dec07f923 594 SUPERFAMILY SSF82771 15 97 1.07E-21 T 21-04-2016 IPR000305 GIY-YIG nuclease superfamily HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS02615 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06530 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06400 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS05755 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS02130 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF01527 Transposase 60 113 5.1E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 11 66 9.0E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 135 219 2.8E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 Gene3D G3DSA:1.10.10.60 67 134 2.2E-7 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 Pfam PF13518 Helix-turn-helix domain 132 181 1.1E-13 T 21-04-2016 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 39 107 1.88E-13 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS06645 7bada2f96bd5140003f7b309cfcb67d9 225 SUPERFAMILY SSF48295 117 183 1.78E-17 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 235 6.5E-113 T 21-04-2016 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Gene3D G3DSA:3.40.50.300 20 174 7.6E-31 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Gene3D G3DSA:1.10.10.10 257 328 4.6E-32 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 326 3.6E-139 T 21-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 PANTHER PTHR13779 1 327 1.6E-172 T 21-04-2016 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 253 326 9.8E-31 T 21-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 SUPERFAMILY SSF46785 257 328 8.34E-23 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 SMART SM00382 51 185 5.2E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 250 332 9.0E-41 T 21-04-2016 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 SUPERFAMILY SSF52540 20 251 4.59E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Gene3D G3DSA:1.10.8.60 185 255 3.3E-33 T 21-04-2016 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 333 166.816 T 21-04-2016 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 HSISS4_RS09360 e6d52c8021005ee4a0b72ed73fa38908 333 PANTHER PTHR13779:SF25 1 327 1.6E-172 T 21-04-2016 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 Gene3D G3DSA:3.30.160.20 9 71 4.6E-32 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 ProSitePatterns PS00585 Ribosomal protein S5 signature. 27 59 - T 21-04-2016 IPR018192 Ribosomal protein S5, N-terminal, conserved site HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 SUPERFAMILY SSF54211 79 157 1.97E-24 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 161 9.3E-67 T 21-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 SUPERFAMILY SSF54768 8 75 2.72E-24 T 21-04-2016 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 Gene3D G3DSA:3.30.230.10 75 157 3.3E-31 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 156 6.8E-28 T 21-04-2016 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 Pfam PF00333 Ribosomal protein S5, N-terminal domain 10 74 9.2E-32 T 21-04-2016 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 162 35.344 T 21-04-2016 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09265 f2238d174131841d1b630773aef16141 164 PANTHER PTHR13718 9 160 4.9E-71 T 21-04-2016 IPR000851 Ribosomal protein S5 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 108.343 T 21-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 Gene3D G3DSA:1.10.1270.20 155 237 1.6E-37 T 21-04-2016 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 PIRSF PIRSF000386 1 239 5.7E-98 T 21-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 PANTHER PTHR32125 1 222 2.8E-111 T 21-04-2016 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 SUPERFAMILY SSF75217 1 237 1.16E-93 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 PANTHER PTHR32125:SF1 1 222 2.8E-111 T 21-04-2016 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 215 3.6E-65 T 21-04-2016 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 228 5.3E-92 T 21-04-2016 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 HSISS4_RS06875 1bf97968764c3287a76c286c2b8c701c 239 Gene3D G3DSA:3.40.1280.10 1 154 7.5E-60 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 271 2.5E-87 T 21-04-2016 IPR011862 Phosphate binding protein GO:0006810 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 SUPERFAMILY SSF53850 33 279 1.57E-75 T 21-04-2016 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 Gene3D G3DSA:3.40.190.10 109 231 3.2E-43 T 21-04-2016 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 Gene3D G3DSA:3.40.190.10 232 272 4.3E-4 T 21-04-2016 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 PANTHER PTHR30570 20 286 4.4E-139 T 21-04-2016 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 PANTHER PTHR30570:SF4 20 286 4.4E-139 T 21-04-2016 HSISS4_RS04895 bc730448a72aa711b81122a2ea5e2afc 291 Pfam PF12849 PBP superfamily domain 31 258 3.4E-35 T 21-04-2016 IPR024370 PBP domain HSISS4_RS06055 1ca721f3ed06d5507033d9dd07134415 261 PANTHER PTHR36833 1 261 8.0E-131 T 21-04-2016 HSISS4_RS06055 1ca721f3ed06d5507033d9dd07134415 261 PANTHER PTHR36833:SF1 1 261 8.0E-131 T 21-04-2016 HSISS4_RS06055 1ca721f3ed06d5507033d9dd07134415 261 Pfam PF06182 ABC-2 family transporter protein 35 260 5.1E-74 T 21-04-2016 IPR010390 Protein of unknown function DUF990 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 SMART SM00448 2 111 5.0E-33 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 Gene3D G3DSA:1.10.10.10 125 218 7.6E-27 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 217 1.1E-20 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 PANTHER PTHR26402:SF261 2 218 6.3E-70 T 21-04-2016 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 SMART SM00862 144 218 1.0E-19 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 Gene3D G3DSA:3.40.50.2300 2 122 2.3E-33 T 21-04-2016 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 Pfam PF00072 Response regulator receiver domain 4 111 4.0E-23 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 PANTHER PTHR26402 2 218 6.3E-70 T 21-04-2016 HSISS4_RS05360 68329da20b664867fa423ddffe2acbc1 219 SUPERFAMILY SSF52172 2 173 3.27E-35 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 Pfam PF00005 ABC transporter 333 455 6.5E-18 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 Pfam PF00005 ABC transporter 20 155 2.0E-14 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 SMART SM00382 341 500 5.4E-6 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 SMART SM00382 28 200 0.0056 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 PANTHER PTHR19211 276 506 1.0E-60 T 21-04-2016 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 PANTHER PTHR19211 1 251 1.0E-60 T 21-04-2016 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 Gene3D G3DSA:3.40.50.300 2 255 4.2E-35 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 Gene3D G3DSA:3.40.50.300 328 500 1.5E-29 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 SUPERFAMILY SSF52540 301 502 1.38E-30 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 PANTHER PTHR19211:SF45 276 506 1.0E-60 T 21-04-2016 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 PANTHER PTHR19211:SF45 1 251 1.0E-60 T 21-04-2016 HSISS4_RS06800 9515111c79d227ddf92b772bd4453c44 507 SUPERFAMILY SSF52540 2 197 3.4E-31 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Gene3D G3DSA:1.10.3060.10 601 789 1.2E-47 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Gene3D G3DSA:3.40.50.300 6 226 7.4E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Gene3D G3DSA:3.40.50.300 350 397 7.4E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Pfam PF07516 SecA Wing and Scaffold domain 571 787 6.6E-55 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SUPERFAMILY SSF81886 573 836 4.19E-69 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Pfam PF07517 SecA DEAD-like domain 8 383 2.3E-124 T 21-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 ProSitePatterns PS01312 SecA family signature. 481 496 - T 21-04-2016 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SUPERFAMILY SSF52540 397 567 2.05E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Pfam PF02810 SEC-C motif 828 846 4.9E-8 T 21-04-2016 IPR004027 SEC-C motif HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SUPERFAMILY SSF52540 12 226 9.35E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 497 1.7E-229 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SMART SM00958 227 339 2.0E-57 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Gene3D G3DSA:3.40.50.300 398 568 1.3E-78 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SMART SM00957 5 383 8.6E-265 T 21-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SUPERFAMILY SSF81767 231 349 7.59E-41 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 SUPERFAMILY SSF52540 349 396 9.35E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PANTHER PTHR30612 1 849 0.0 T 21-04-2016 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Gene3D G3DSA:3.90.1440.10 230 349 6.1E-42 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 61 85 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 320 342 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 168 188 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 394 407 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 115 125 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 99 113 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 PRINTS PR00906 SecA protein signature 357 374 3.0E-69 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Pfam PF01043 SecA preprotein cross-linking domain 231 339 8.2E-34 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS08335 6ede520a0cbe668422254ed26fbf2515 849 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 790 19.171 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 PANTHER PTHR24220:SF453 4 206 1.4E-84 T 21-04-2016 HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 SMART SM00382 27 200 6.0E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 SUPERFAMILY SSF52540 3 213 1.38E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 PANTHER PTHR24220 4 206 1.4E-84 T 21-04-2016 HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 Pfam PF00005 ABC transporter 18 152 2.6E-24 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05375 e93366f1733af028852a138e30cf25e4 224 Gene3D G3DSA:3.40.50.300 2 210 1.7E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Gene3D G3DSA:3.30.70.250 4 83 1.4E-33 T 21-04-2016 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Gene3D G3DSA:2.160.10.10 86 221 7.2E-48 T 21-04-2016 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 PANTHER PTHR23416:SF50 53 232 5.8E-50 T 21-04-2016 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 161 196 2.3E-11 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 SUPERFAMILY SSF51161 84 219 4.06E-48 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 3 231 41.646 T 21-04-2016 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941|UniPathway: UPA00034 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 6 82 1.9E-22 T 21-04-2016 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941|UniPathway: UPA00034 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 8 232 9.5E-111 T 21-04-2016 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941|UniPathway: UPA00034 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 PANTHER PTHR23416 53 232 5.8E-50 T 21-04-2016 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 170 198 - T 21-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 21-04-2016 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: REACT_17015 HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 115 0.0012 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS08930 c539381f71091f3d4536583d2ba9f43e 232 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 1.5E-8 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF50249 616 698 9.29E-21 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF54211 297 490 1.77E-43 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF00575 S1 RNA binding domain 622 693 2.4E-19 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SMART SM00316 623 693 2.0E-22 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF01138 3' exoribonuclease family, domain 1 326 459 1.9E-14 T 21-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF01138 3' exoribonuclease family, domain 1 12 142 1.3E-20 T 21-04-2016 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF55666 143 233 6.03E-25 T 21-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 PIRSF PIRSF005499 1 727 9.3E-283 T 21-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Gene3D G3DSA:3.30.230.70 5 222 1.6E-80 T 21-04-2016 IPR027408 PNPase/RNase PH domain HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Gene3D G3DSA:3.30.230.70 314 546 5.8E-83 T 21-04-2016 IPR027408 PNPase/RNase PH domain HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 2 696 29.09 T 21-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF55666 453 551 1.4E-27 T 21-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF46915 236 323 7.59E-14 T 21-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF03725 3' exoribonuclease family, domain 2 462 530 2.7E-6 T 21-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 1.5E-9 T 21-04-2016 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: REACT_21257 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Gene3D G3DSA:2.40.50.140 624 694 1.3E-23 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF00013 KH domain 560 616 2.7E-11 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF54211 6 142 7.59E-47 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 323 1.6E-11 T 21-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 10 694 6.8E-296 T 21-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Gene3D G3DSA:1.10.10.400 228 313 8.6E-33 T 21-04-2016 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 PANTHER PTHR11252 1 745 0.0 T 21-04-2016 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 PANTHER PTHR11252:SF0 1 745 0.0 T 21-04-2016 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 Gene3D G3DSA:3.30.1370.10 554 623 3.2E-23 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SUPERFAMILY SSF54791 560 642 2.19E-21 T 21-04-2016 IPR004088 K Homology domain, type 1 GO:0003723 HSISS4_RS00510 390e434c34d731bf999a1a9d82a0fb49 745 SMART SM00322 555 620 2.3E-11 T 21-04-2016 IPR004087 K Homology domain GO:0003676 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 Pfam PF03838 Recombination protein U 28 190 5.5E-64 T 21-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 PIRSF PIRSF037785 19 198 4.5E-78 T 21-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 198 95.509 T 21-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 SUPERFAMILY SSF52980 30 194 2.2E-63 T 21-04-2016 IPR011335 Restriction endonuclease type II-like HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 PANTHER PTHR41275 1 194 1.6E-90 T 21-04-2016 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 Gene3D G3DSA:3.40.1350.10 29 194 1.8E-72 T 21-04-2016 IPR011856 tRNA endonuclease-like domain GO:0003676|GO:0004518 HSISS4_RS01115 d2face26f90a5e97e9cd418fb6d11eb8 198 TIGRFAM TIGR00648 recU: recombination protein U 27 193 5.8E-63 T 21-04-2016 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 HSISS4_RS06100 0a0d82e7e5d2236413b71692a5cd0f99 312 PANTHER PTHR10361 1 306 4.0E-81 T 21-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 HSISS4_RS06100 0a0d82e7e5d2236413b71692a5cd0f99 312 Pfam PF01758 Sodium Bile acid symporter family 43 219 2.5E-38 T 21-04-2016 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 18 226 1.2E-36 T 21-04-2016 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 6 489 5.0E-262 T 21-04-2016 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 PIRSF PIRSF006005 1 492 2.5E-235 T 21-04-2016 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 PANTHER PTHR39191 3 493 4.5E-179 T 21-04-2016 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 242 435 8.5E-36 T 21-04-2016 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 493 272.834 T 21-04-2016 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 254 271 - T 21-04-2016 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06380 92b0b2de6819c9452419b54f7351bc7f 493 PANTHER PTHR39191:SF1 3 493 4.5E-179 T 21-04-2016 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 Pfam PF00698 Acyl transferase domain 6 279 3.2E-41 T 21-04-2016 IPR014043 Acyl transferase HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 SUPERFAMILY SSF52151 4 120 2.88E-75 T 21-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 SUPERFAMILY SSF52151 188 305 2.88E-75 T 21-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 288 3.0E-102 T 21-04-2016 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 PIRSF PIRSF000446 1 306 6.1E-103 T 21-04-2016 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388|UniPathway: UPA00094 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 Gene3D G3DSA:3.40.366.10 195 295 4.4E-71 T 21-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 Gene3D G3DSA:3.40.366.10 3 120 4.4E-71 T 21-04-2016 IPR001227 Acyl transferase domain GO:0008152|GO:0016740 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 302 4.2E-46 T 21-04-2016 IPR020801 Polyketide synthase, acyl transferase domain HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 Gene3D G3DSA:3.30.70.250 123 194 2.4E-29 T 21-04-2016 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 SUPERFAMILY SSF55048 126 195 1.18E-17 T 21-04-2016 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 HSISS4_RS01805 8a0bdfadeaf1e8c87315ed7108a5008c 306 PANTHER PTHR10982 3 305 3.6E-138 T 21-04-2016 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 Pfam PF01795 MraW methylase family 4 314 1.1E-132 T 21-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 PANTHER PTHR11265:SF0 1 316 1.7E-148 T 21-04-2016 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 37.501 T 21-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 313 5.8E-119 T 21-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 PIRSF PIRSF004486 1 315 9.2E-109 T 21-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 Gene3D G3DSA:1.10.150.170 117 221 4.3E-39 T 21-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 SUPERFAMILY SSF81799 118 219 4.58E-35 T 21-04-2016 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 Gene3D G3DSA:3.40.50.150 222 315 1.3E-49 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 Gene3D G3DSA:3.40.50.150 7 114 1.3E-49 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 SUPERFAMILY SSF53335 6 117 2.58E-44 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 SUPERFAMILY SSF53335 219 314 2.58E-44 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08155 3005d4e9d69d0c88dc26b2443dfb7b3c 316 PANTHER PTHR11265 1 316 1.7E-148 T 21-04-2016 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PANTHER PTHR11444:SF3 1 459 2.1E-232 T 21-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Gene3D G3DSA:1.10.275.10 6 110 4.2E-39 T 21-04-2016 IPR024083 Fumarase/histidase, N-terminal HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 SUPERFAMILY SSF48557 7 459 2.36E-151 T 21-04-2016 IPR008948 L-Aspartase-like GO:0003824 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Hamap MF_00006 Argininosuccinate lyase [argH]. 6 457 43.033 T 21-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PANTHER PTHR11444 1 459 2.1E-232 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 21-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Pfam PF14698 Argininosuccinate lyase C-terminal 367 434 9.3E-23 T 21-04-2016 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00149 Fumarate lyase superfamily signature 106 124 2.0E-28 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 2.0E-28 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 2.0E-28 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 2.0E-28 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Gene3D G3DSA:1.20.200.10 111 378 2.8E-103 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 TIGRFAM TIGR00838 argH: argininosuccinate lyase 7 459 3.8E-196 T 21-04-2016 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Pfam PF00206 Lyase 10 304 1.2E-74 T 21-04-2016 IPR022761 Fumarate lyase, N-terminal HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 Gene3D G3DSA:1.10.40.30 379 435 2.3E-27 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 4.0E-66 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 105 127 4.0E-66 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 4.0E-66 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 4.0E-66 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 4.0E-66 T 21-04-2016 HSISS4_RS08800 a15633c1a22a341950a2d0dd18378cfd 461 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 4.0E-66 T 21-04-2016 HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 SUPERFAMILY SSF51419 1 222 7.59E-71 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 PIRSF PIRSF004848 1 227 5.8E-67 T 21-04-2016 IPR011078 Uncharacterised protein family UPF0001 HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 224 1.6E-54 T 21-04-2016 IPR011078 Uncharacterised protein family UPF0001 HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 Gene3D G3DSA:3.20.20.10 1 225 3.0E-75 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 Pfam PF01168 Alanine racemase, N-terminal domain 13 223 7.6E-20 T 21-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS03645 3f02e9c70c738e07a0b6f0add198a70f 227 PANTHER PTHR10146 1 222 2.1E-78 T 21-04-2016 IPR011078 Uncharacterised protein family UPF0001 HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 Pfam PF11967 Recombination protein O N terminal 1 77 9.4E-18 T 21-04-2016 IPR022572 DNA replication/recombination mediator RecO, N-terminal HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 242 1.7E-70 T 21-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 SUPERFAMILY SSF50249 2 78 2.23E-13 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 Hamap MF_00201 DNA repair protein RecO [recO]. 2 243 24.562 T 21-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 Pfam PF02565 Recombination protein O C terminal 83 237 9.0E-35 T 21-04-2016 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 Gene3D G3DSA:2.40.50.140 2 81 5.0E-8 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 SUPERFAMILY SSF57863 80 232 8.63E-37 T 21-04-2016 HSISS4_RS00200 4f9b0dc0d464e2551be7e49a62a04416 257 PANTHER PTHR33991 2 253 3.0E-53 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF55326 195 231 3.03E-32 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF55326 289 429 3.03E-32 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Pfam PF02769 AIR synthase related protein, C-terminal domain 439 590 1.0E-24 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF56042 440 605 1.47E-38 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Gene3D G3DSA:3.30.1330.10 647 806 7.9E-25 T 21-04-2016 IPR016188 PurM-like, N-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF55326 630 811 8.11E-37 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 977 1238 1.3E-81 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Gene3D G3DSA:3.30.1330.10 286 430 3.7E-54 T 21-04-2016 IPR016188 PurM-like, N-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Gene3D G3DSA:3.30.1330.10 220 235 3.7E-54 T 21-04-2016 IPR016188 PurM-like, N-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 TIGRFAM TIGR01857 FGAM-synthase: phosphoribosylformylglycinamidine synthase 3 1238 0.0 T 21-04-2016 IPR010141 Phosphoribosylformylglycinamidine synthase, FGAM HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 Gene3D G3DSA:3.40.50.880 979 1217 1.1E-14 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 PANTHER PTHR10099 2 235 6.5E-280 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 PANTHER PTHR10099 266 1241 6.5E-280 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 PANTHER PTHR10099:SF1 2 235 6.5E-280 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 PANTHER PTHR10099:SF1 266 1241 6.5E-280 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF56042 813 969 8.79E-11 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SMART SM01211 976 1238 1.7E-106 T 21-04-2016 HSISS4_RS00220 093b0bae511c1367d7df5ec395cba38f 1241 SUPERFAMILY SSF52317 975 1238 5.98E-65 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 331 3.1E-78 T 21-04-2016 IPR006330 Adenosine/adenine deaminase GO:0019239 HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 PANTHER PTHR11409 11 335 3.2E-80 T 21-04-2016 HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 Hamap MF_00540 Adenosine deaminase [add]. 4 332 55.879 T 21-04-2016 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 Pfam PF00962 Adenosine/AMP deaminase 9 330 7.8E-53 T 21-04-2016 IPR001365 Adenosine/AMP deaminase domain GO:0019239 HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 Gene3D G3DSA:3.20.20.140 6 335 4.6E-90 T 21-04-2016 HSISS4_RS05810 98d477cd614bcc5b1e73c641e2072c91 336 SUPERFAMILY SSF51556 7 334 8.96E-72 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 Pfam PF00005 ABC transporter 350 497 1.8E-31 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 Gene3D G3DSA:1.20.1560.10 4 318 1.8E-64 T 21-04-2016 HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 SMART SM00382 359 551 3.4E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 SUPERFAMILY SSF52540 321 569 2.78E-84 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 Pfam PF00664 ABC transporter transmembrane region 17 279 9.7E-37 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 Gene3D G3DSA:3.40.50.300 331 563 2.0E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 SUPERFAMILY SSF90123 4 313 1.44E-64 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS02520 ca7800aa1c37cbc4328aa6dc3de7e234 578 PANTHER PTHR24221 1 578 2.1E-181 T 21-04-2016 HSISS4_RS07110 fb3e2d10e94e18abfd31684b8495b31c 110 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 2.4E-30 T 21-04-2016 IPR019277 Protein of unknown function DUF2304 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PANTHER PTHR22855 1 256 6.0E-92 T 21-04-2016 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 SUPERFAMILY SSF52096 8 255 2.56E-81 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 8 256 3.7E-105 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PANTHER PTHR22855:SF42 1 256 6.0E-92 T 21-04-2016 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 100 113 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 116 129 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 144 153 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 35 46 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 81 97 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 60 78 9.6E-43 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 1 256 36.0 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 9 95 3.1E-38 T 21-04-2016 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00253+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-6722|MetaCyc: PWY-7388|UniPathway: UPA00655 HSISS4_RS01840 436c94aa6c819243348740a1af5a84ec 256 Gene3D G3DSA:3.90.226.10 9 215 1.1E-48 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SMART SM00491 665 792 1.4E-6 T 21-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Pfam PF00929 Exonuclease 11 162 2.3E-24 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Pfam PF13307 Helicase C-terminal domain 650 803 4.9E-25 T 21-04-2016 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SMART SM00487 244 510 1.0E-7 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.30.420.10 6 173 1.3E-44 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 7 173 2.4E-26 T 21-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 PANTHER PTHR30231 7 466 1.0E-149 T 21-04-2016 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SUPERFAMILY SSF52540 398 469 2.26E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SUPERFAMILY SSF52540 577 591 2.26E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SUPERFAMILY SSF52540 619 780 2.26E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SUPERFAMILY SSF52540 263 314 2.26E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SMART SM00479 8 172 9.4E-34 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Pfam PF00270 DEAD/DEAH box helicase 263 319 1.5E-6 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.40.50.300 634 722 1.5E-7 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.40.50.300 755 810 1.5E-7 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 8 508 2.5E-167 T 21-04-2016 IPR006310 DnaQ exonuclease/DinG helicase, predicted HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 SUPERFAMILY SSF53098 8 191 4.34E-46 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 PANTHER PTHR30231:SF8 7 466 1.0E-149 T 21-04-2016 HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.40.50.300 250 312 6.0E-17 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.40.50.300 579 588 6.0E-17 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05605 dbb6ca12b5b3fce5cfc5af89021a064a 828 Gene3D G3DSA:3.40.50.300 385 478 6.0E-17 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 PANTHER PTHR23105:SF5 21 229 5.5E-79 T 21-04-2016 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 Gene3D G3DSA:3.30.190.20 161 227 2.2E-44 T 21-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 Gene3D G3DSA:3.30.190.20 17 68 2.2E-44 T 21-04-2016 IPR016094 Ribosomal protein L1, 2-layer alpha/beta-sandwich GO:0003723 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 PANTHER PTHR23105 21 229 5.5E-79 T 21-04-2016 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 Pfam PF00687 Ribosomal protein L1p/L10e family 35 219 7.7E-52 T 21-04-2016 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 SUPERFAMILY SSF56808 6 227 1.83E-82 T 21-04-2016 IPR023674 Ribosomal protein L1-like HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 43.172 T 21-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 2.9E-102 T 21-04-2016 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 Gene3D G3DSA:3.40.50.790 69 159 1.5E-43 T 21-04-2016 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 139 - T 21-04-2016 IPR023673 Ribosomal protein L1, conserved site HSISS4_RS08845 9ce6352f6b928921cb6be54f35888897 229 PIRSF PIRSF002155 1 227 2.1E-78 T 21-04-2016 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 PRINTS PR00812 Bacterial general secretion pathway protein F signature 266 285 3.1E-6 T 21-04-2016 IPR003004 GspF/PilC family HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 PRINTS PR00812 Bacterial general secretion pathway protein F signature 250 264 3.1E-6 T 21-04-2016 IPR003004 GspF/PilC family HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 PRINTS PR00812 Bacterial general secretion pathway protein F signature 57 85 3.1E-6 T 21-04-2016 IPR003004 GspF/PilC family HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 PANTHER PTHR30012 1 286 7.9E-49 T 21-04-2016 HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 Pfam PF00482 Type II secretion system (T2SS), protein F 4 85 2.1E-5 T 21-04-2016 IPR018076 Type II secretion system F domain HSISS4_RS09070 b85e2d4a7ef7075e5af3ad3f6ceb670b 287 Pfam PF00482 Type II secretion system (T2SS), protein F 157 277 2.3E-17 T 21-04-2016 IPR018076 Type II secretion system F domain HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 Gene3D G3DSA:3.40.640.10 37 282 2.4E-85 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 Gene3D G3DSA:3.90.1150.10 283 399 6.8E-30 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 Pfam PF00266 Aminotransferase class-V 26 395 1.2E-151 T 21-04-2016 IPR000192 Aminotransferase class V domain HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 SUPERFAMILY SSF53383 5 400 9.41E-126 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 PANTHER PTHR11601:SF17 6 407 5.8E-202 T 21-04-2016 HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 PANTHER PTHR11601 6 407 5.8E-202 T 21-04-2016 HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 PIRSF PIRSF005572 23 407 1.3E-48 T 21-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 216 235 - T 21-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HSISS4_RS00870 908714fe817c7e617c2ee9f7170f9345 410 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 8 406 8.2E-182 T 21-04-2016 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 957 1048 6.02E-21 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 572 616 1.3E-13 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 906 935 2.7E-13 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 828 858 2.7E-13 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 837 955 1.07E-25 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 518 612 1.07E-25 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 644 671 1.07E-25 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 420 480 4.0E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 483 543 3.4E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 976 1036 4.6E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 576 635 1.4E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 153 213 4.7E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 835 894 1.7E-13 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 245 298 2.4E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 485 555 8.5E-20 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 147 218 7.6E-14 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 960 1048 8.1E-19 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 144 224 2.16E-14 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 2.8E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 235 253 0.18 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 410 428 0.0085 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 348 361 0.19 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 145 158 0.67 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 327 341 0.3 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 917 934 0.001 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 566 584 0.81 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 474 492 0.0053 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 432 447 0.35 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Pfam PF01473 Putative cell wall binding repeat 587 603 0.26 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 313 361 1.41E-8 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 393 530 3.18E-43 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 SUPERFAMILY SSF69360 239 329 3.18E-43 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.20.120.10 219 256 3.3E-5 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 257 311 4.4E-15 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 384 424 6.6E-9 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 647 681 2.1E-4 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 425 484 1.7E-18 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 859 888 2.1E-4 T 21-04-2016 HSISS4_RS06235 1686f1ab1a7f5d067ce8959434e243a9 1049 Gene3D G3DSA:2.10.270.10 314 363 2.9E-9 T 21-04-2016 HSISS4_RS03355 e3b7252f20220798781af8dedf55fad3 309 PANTHER PTHR30217:SF7 1 308 2.6E-153 T 21-04-2016 HSISS4_RS03355 e3b7252f20220798781af8dedf55fad3 309 Pfam PF01136 Peptidase family U32 74 306 7.5E-46 T 21-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HSISS4_RS03355 e3b7252f20220798781af8dedf55fad3 309 PANTHER PTHR30217 1 308 2.6E-153 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 Gene3D G3DSA:3.10.580.10 1 132 1.0E-34 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 Pfam PF00571 CBS domain 77 131 5.0E-13 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 Pfam PF00571 CBS domain 3 55 4.6E-15 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 PANTHER PTHR11911 1 196 1.5E-51 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 Gene3D G3DSA:3.30.70.260 141 200 8.0E-7 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 SUPERFAMILY SSF55021 143 210 2.75E-6 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 SUPERFAMILY SSF54631 1 132 1.26E-34 T 21-04-2016 HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 SMART SM00116 10 57 1.7E-10 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 SMART SM00116 84 131 2.0E-9 T 21-04-2016 IPR000644 CBS domain HSISS4_RS01660 32b73894830ef7dfead6f332e755c344 219 PANTHER PTHR11911:SF104 1 196 1.5E-51 T 21-04-2016 HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 5 252 28.29 T 21-04-2016 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 PANTHER PTHR12428 7 302 3.8E-84 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 60 248 2.7E-46 T 21-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 Pfam PF02096 60Kd inner membrane protein 60 248 7.3E-42 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 PANTHER PTHR12428:SF20 7 302 3.8E-84 T 21-04-2016 HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 PRINTS PR00701 60kDa inner membrane protein signature 132 155 3.5E-8 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS01175 c57b38b735f14442602d9761f609f77f 305 PRINTS PR00701 60kDa inner membrane protein signature 215 238 3.5E-8 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 Pfam PF00005 ABC transporter 337 477 3.1E-25 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 SMART SM00382 343 524 3.6E-12 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 PANTHER PTHR24221:SF161 4 506 6.7E-55 T 21-04-2016 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 PANTHER PTHR24221 4 506 6.7E-55 T 21-04-2016 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 SUPERFAMILY SSF52540 312 523 1.23E-39 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 Pfam PF00664 ABC transporter transmembrane region 16 275 2.1E-11 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 Gene3D G3DSA:3.40.50.300 320 523 5.5E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 Gene3D G3DSA:1.20.1560.10 3 293 1.9E-27 T 21-04-2016 HSISS4_RS00940 1a8cd411206dcb560130d10e0acab48f 525 SUPERFAMILY SSF90123 2 292 2.88E-38 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 Pfam PF00664 ABC transporter transmembrane region 23 295 4.7E-41 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 PANTHER PTHR24221 3 583 5.5E-205 T 21-04-2016 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 Gene3D G3DSA:3.40.50.300 347 567 3.1E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 Pfam PF00005 ABC transporter 355 502 1.4E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 Gene3D G3DSA:1.20.1560.10 10 322 1.2E-70 T 21-04-2016 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 SUPERFAMILY SSF52540 341 575 1.52E-78 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 SUPERFAMILY SSF90123 10 328 2.22E-76 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 SMART SM00382 364 550 9.0E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08095 e04b30498b30f30698f29888ee649418 585 PANTHER PTHR24221:SF240 3 583 5.5E-205 T 21-04-2016 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PANTHER PTHR22778 8 165 1.4E-29 T 21-04-2016 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PANTHER PTHR22778:SF16 8 165 1.4E-29 T 21-04-2016 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 16 38 - T 21-04-2016 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 Pfam PF00186 Dihydrofolate reductase 5 164 4.5E-53 T 21-04-2016 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PIRSF PIRSF000194 1 167 5.0E-52 T 21-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PRINTS PR00070 Dihydrofolate reductase signature 16 26 9.2E-11 T 21-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PRINTS PR00070 Dihydrofolate reductase signature 43 54 9.2E-11 T 21-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PRINTS PR00070 Dihydrofolate reductase signature 96 110 9.2E-11 T 21-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 PRINTS PR00070 Dihydrofolate reductase signature 30 38 9.2E-11 T 21-04-2016 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 SUPERFAMILY SSF53597 4 165 2.88E-50 T 21-04-2016 IPR024072 Dihydrofolate reductase-like domain HSISS4_RS02720 5998ebff97c79b40b714909ed3f3da6e 167 Gene3D G3DSA:3.40.430.10 4 165 7.6E-52 T 21-04-2016 IPR024072 Dihydrofolate reductase-like domain HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 PANTHER PTHR12358 2 289 1.9E-41 T 21-04-2016 HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 Gene3D G3DSA:3.40.50.10330 28 111 4.0E-8 T 21-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 287 2.7E-44 T 21-04-2016 IPR005218 Diacylglycerol/lipid kinase HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 126 1.7E-29 T 21-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 SUPERFAMILY SSF111331 1 289 1.22E-59 T 21-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain HSISS4_RS03205 3a9430b74eb4ddf55152abdedc7ac146 293 SMART SM00046 3 131 3.6E-5 T 21-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Gene3D G3DSA:3.30.70.270 79 177 1.3E-31 T 21-04-2016 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 SUPERFAMILY SSF100879 251 351 3.73E-25 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 PANTHER PTHR11076 1 365 2.9E-138 T 21-04-2016 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Pfam PF00817 impB/mucB/samB family 17 167 2.3E-50 T 21-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Pfam PF11799 impB/mucB/samB family C-terminal domain 248 360 1.6E-19 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Hamap MF_01113 DNA polymerase IV [dinB]. 11 363 37.916 T 21-04-2016 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Pfam PF11798 IMS family HHH motif 179 210 2.0E-7 T 21-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Gene3D G3DSA:3.30.1490.100 254 361 1.2E-28 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 Gene3D G3DSA:1.10.150.20 179 247 2.5E-22 T 21-04-2016 HSISS4_RS08020 d912651a037f7b02ae4a502a6525eaff 368 SUPERFAMILY SSF56672 3 247 2.13E-92 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PANTHER PTHR11451 263 336 6.2E-100 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PANTHER PTHR11451 4 247 6.2E-100 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 5 326 4.5E-115 T 21-04-2016 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 5 481 1.1E-169 T 21-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 SUPERFAMILY SSF52374 5 319 1.93E-104 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 SUPERFAMILY SSF48163 320 480 6.8E-41 T 21-04-2016 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Gene3D G3DSA:1.10.1160.10 251 335 5.9E-34 T 21-04-2016 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Gene3D G3DSA:3.40.50.620 198 247 8.5E-52 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Gene3D G3DSA:3.40.50.620 5 69 8.5E-52 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Gene3D G3DSA:3.90.800.10 70 197 1.8E-33 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Gene3D G3DSA:1.10.10.350 382 481 1.8E-18 T 21-04-2016 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 Hamap MF_00022_B Glutamate--tRNA ligase [gltX]. 5 481 33.919 T 21-04-2016 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PANTHER PTHR11451:SF41 263 336 6.2E-100 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PANTHER PTHR11451:SF41 4 247 6.2E-100 T 21-04-2016 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 5.2E-28 T 21-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 5.2E-28 T 21-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 196 206 5.2E-28 T 21-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 5.2E-28 T 21-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS08835 06bb7cc450d4cb71e787d9915ba17fe1 484 PRINTS PR00987 Glutamyl-tRNA synthetase signature 212 220 5.2E-28 T 21-04-2016 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 SUPERFAMILY SSF52374 413 658 2.6E-137 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 SUPERFAMILY SSF52374 3 226 2.6E-137 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Pfam PF08264 Anticodon-binding domain of tRNA 684 794 6.7E-18 T 21-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 3 832 22.649 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946:SF7 609 832 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946:SF7 240 265 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946:SF7 4 207 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946:SF7 471 575 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946:SF7 288 453 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Gene3D G3DSA:3.90.740.10 223 421 3.3E-62 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 SUPERFAMILY SSF50677 226 412 5.55E-56 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Gene3D G3DSA:1.10.730.10 639 768 3.5E-37 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 53 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 833 0.0 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 401 2.5E-67 T 21-04-2016 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 414 571 3.3E-5 T 21-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 609 636 1.4E-6 T 21-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Pfam PF09334 tRNA synthetases class I (M) 40 164 3.3E-16 T 21-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946 609 832 0.0 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946 240 265 0.0 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946 4 207 0.0 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946 471 575 0.0 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PANTHER PTHR11946 288 453 0.0 T 21-04-2016 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Gene3D G3DSA:3.40.50.620 3 222 1.3E-158 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Gene3D G3DSA:3.40.50.620 609 638 1.3E-158 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 Gene3D G3DSA:3.40.50.620 422 574 1.3E-158 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 SUPERFAMILY SSF47323 653 833 5.42E-32 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 486 504 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 558 568 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 186 199 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS01040 0e8d2126d43b880264f6a68611671ee5 833 PRINTS PR00985 Leucyl-tRNA synthetase signature 525 547 9.4E-55 T 21-04-2016 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 SMART SM00345 7 66 3.4E-14 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PANTHER PTHR11751 1 69 1.3E-26 T 21-04-2016 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PANTHER PTHR11751 117 140 1.3E-26 T 21-04-2016 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 Gene3D G3DSA:3.40.1410.10 62 235 5.2E-48 T 21-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 3 234 7.3E-90 T 21-04-2016 IPR012770 Trehalose operon transcriptional repressor HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 SUPERFAMILY SSF46785 2 70 3.13E-19 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 7.6E-10 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 7.6E-10 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PANTHER PTHR11751:SF347 1 69 1.3E-26 T 21-04-2016 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 PANTHER PTHR11751:SF347 117 140 1.3E-26 T 21-04-2016 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.4E-17 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 SUPERFAMILY SSF64288 72 231 1.21E-36 T 21-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 SMART SM00866 88 227 7.3E-21 T 21-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 Pfam PF07702 UTRA domain 88 227 7.6E-29 T 21-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HSISS4_RS09175 c3f2b03926aade2270e031fb04377db3 236 Gene3D G3DSA:1.10.10.10 2 61 3.6E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05335 bcd37848c821320985afc4fb4e1913bc 97 SUPERFAMILY SSF52821 8 95 1.11E-22 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS05335 bcd37848c821320985afc4fb4e1913bc 97 Pfam PF00581 Rhodanese-like domain 10 84 5.2E-12 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS05335 bcd37848c821320985afc4fb4e1913bc 97 Gene3D G3DSA:3.40.250.10 5 96 2.9E-20 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS05335 bcd37848c821320985afc4fb4e1913bc 97 SMART SM00450 1 94 4.6E-14 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 SUPERFAMILY SSF51735 4 247 6.28E-56 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.2E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.2E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.2E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.2E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.2E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 Gene3D G3DSA:3.40.50.720 4 226 5.9E-56 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.3E-12 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 5.3E-12 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.3E-12 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 Pfam PF00106 short chain dehydrogenase 6 188 4.2E-48 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PANTHER PTHR24322 148 180 4.7E-58 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PANTHER PTHR24322 9 132 4.7E-58 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PANTHER PTHR24322:SF509 148 180 4.7E-58 T 21-04-2016 HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 PANTHER PTHR24322:SF509 9 132 4.7E-58 T 21-04-2016 HSISS4_RS04015 e73fdc7baff7067f5585a01aa8025e9a 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 21-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 SUPERFAMILY SSF52166 1 206 6.67E-77 T 21-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 2.0E-64 T 21-04-2016 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 2.0E-76 T 21-04-2016 IPR013005 50S ribosomal protein uL4 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 35.647 T 21-04-2016 IPR013005 50S ribosomal protein uL4 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 Gene3D G3DSA:3.40.1370.10 58 207 2.0E-58 T 21-04-2016 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09345 a97c97fcb318a24c0ff9bc61d0723676 207 PANTHER PTHR10746 1 206 1.4E-88 T 21-04-2016 IPR013005 50S ribosomal protein uL4 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 51 368 1.8E-125 T 21-04-2016 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543|UniPathway: UPA00077 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 Gene3D G3DSA:3.20.10.10 463 565 3.5E-29 T 21-04-2016 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 Pfam PF00425 chorismate binding enzyme 111 364 4.2E-89 T 21-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 Pfam PF01063 Amino-transferase class IV 487 566 1.6E-17 T 21-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 Gene3D G3DSA:3.60.120.10 30 369 1.9E-112 T 21-04-2016 IPR005801 ADC synthase GO:0009058 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 SUPERFAMILY SSF56752 320 566 1.57E-34 T 21-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PANTHER PTHR11236 43 453 7.4E-153 T 21-04-2016 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 Gene3D G3DSA:3.30.470.10 383 440 7.2E-5 T 21-04-2016 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PANTHER PTHR11236:SF18 43 453 7.4E-153 T 21-04-2016 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PRINTS PR00095 Anthranilate synthase component I signature 226 239 9.5E-9 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PRINTS PR00095 Anthranilate synthase component I signature 321 335 9.5E-9 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PRINTS PR00095 Anthranilate synthase component I signature 306 320 9.5E-9 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 PRINTS PR00095 Anthranilate synthase component I signature 212 225 9.5E-9 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS05715 94ee297bed1e1d3a59d0d6395be1bf88 576 SUPERFAMILY SSF56322 39 370 8.77E-108 T 21-04-2016 IPR005801 ADC synthase GO:0009058 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 50 218 1.0E-58 T 21-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 Gene3D G3DSA:3.40.50.1360 2 140 1.7E-58 T 21-04-2016 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 SUPERFAMILY SSF100950 2 141 1.98E-43 T 21-04-2016 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 Gene3D G3DSA:3.30.70.260 141 202 1.7E-22 T 21-04-2016 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 222 33.913 T 21-04-2016 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 PANTHER PTHR11934 1 223 3.5E-89 T 21-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 220 1.2E-82 T 21-04-2016 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|UniPathway: UPA00115 HSISS4_RS04550 39d16c4482effc1fffdcd64537bf1f35 226 SUPERFAMILY SSF75445 127 204 7.85E-20 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.30.1490.20 679 737 1.8E-29 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.40.50.1380 931 1052 2.1E-29 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PANTHER PTHR11405:SF5 1 1051 0.0 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Pfam PF02142 MGS-like domain 950 1037 5.8E-18 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SMART SM00851 949 1037 2.3E-24 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.30.470.20 200 398 5.1E-73 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.30.470.20 738 927 6.9E-75 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1058 13.124 T 21-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF48108 395 547 4.58E-52 T 21-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 830 837 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF56059 666 927 5.3E-103 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 702 716 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF52440 1 127 7.77E-50 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SMART SM01209 674 837 0.0018 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:1.10.1030.10 399 531 2.6E-50 T 21-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1057 13.27 T 21-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PANTHER PTHR11405 1 1051 0.0 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 423 540 7.4E-42 T 21-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 666 867 7.1E-37 T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 2.8E-78 T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.7E-62 T 21-04-2016 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF52335 929 1050 6.02E-30 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF56059 128 399 2.65E-106 T 21-04-2016 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1048 0.0 T 21-04-2016 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.40.50.20 4 108 1.0E-43 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SMART SM01096 420 540 1.6E-71 T 21-04-2016 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.40.50.20 532 655 2.6E-58 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 Gene3D G3DSA:3.30.1490.20 142 199 9.7E-26 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS02470 9a8fa1a5f9e913bbb219e23fc73ba883 1059 SUPERFAMILY SSF52440 549 668 2.01E-46 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Pfam PF03129 Anticodon binding domain 330 417 1.4E-13 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Pfam PF13393 Histidyl-tRNA synthetase 8 312 1.7E-44 T 21-04-2016 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 SUPERFAMILY SSF55681 3 319 2.49E-99 T 21-04-2016 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 SUPERFAMILY SSF52954 328 420 8.83E-24 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Gene3D G3DSA:3.40.50.800 326 417 4.2E-28 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 PANTHER PTHR11476 1 425 5.1E-212 T 21-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 PANTHER PTHR11476:SF9 1 425 5.1E-212 T 21-04-2016 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 409 1.9E-156 T 21-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 PIRSF PIRSF001549 1 420 2.8E-122 T 21-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 426 33.96 T 21-04-2016 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21|Reactome: REACT_71 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Gene3D G3DSA:3.30.930.10 1 185 7.9E-100 T 21-04-2016 HSISS4_RS09465 280ca99d652ef76f1a35fcb66fc9dda2 426 Gene3D G3DSA:3.30.930.10 221 321 7.9E-100 T 21-04-2016 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 SUPERFAMILY SSF143800 1 60 3.73E-24 T 21-04-2016 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 62 18.028 T 21-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 56 3.5E-21 T 21-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 Pfam PF00830 Ribosomal L28 family 3 58 1.1E-21 T 21-04-2016 IPR026569 Ribosomal protein L28/L24 GO:0003735 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 Gene3D G3DSA:4.10.1160.10 19 61 9.0E-22 T 21-04-2016 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 PANTHER PTHR39080 2 62 3.0E-22 T 21-04-2016 HSISS4_RS09405 ce366c17ac3cc01287ca2425170ed471 62 PANTHER PTHR39080:SF1 2 62 3.0E-22 T 21-04-2016 HSISS4_RS04750 bc06fdd339902a03942ff0778aa0e826 323 PANTHER PTHR11516 1 323 2.6E-133 T 21-04-2016 HSISS4_RS04750 bc06fdd339902a03942ff0778aa0e826 323 SUPERFAMILY SSF52518 3 323 2.03E-100 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS04750 bc06fdd339902a03942ff0778aa0e826 323 Gene3D G3DSA:3.40.50.970 2 322 2.0E-124 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS04750 bc06fdd339902a03942ff0778aa0e826 323 Pfam PF00676 Dehydrogenase E1 component 15 312 6.5E-85 T 21-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 SUPERFAMILY SSF53062 2 137 2.75E-36 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 Gene3D G3DSA:3.40.50.510 2 143 3.0E-50 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 Gene3D G3DSA:3.40.35.10 169 328 5.5E-64 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 PANTHER PTHR33799 3 330 4.2E-211 T 21-04-2016 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 SUPERFAMILY SSF52728 169 328 1.29E-53 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 Pfam PF03830 PTS system sorbose subfamily IIB component 170 317 8.0E-51 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 Pfam PF03610 PTS system fructose IIA component 4 119 1.7E-34 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS01485 0e489a59876d5998cdd16c5b255c69bf 330 PANTHER PTHR33799:SF7 3 330 4.2E-211 T 21-04-2016 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 PANTHER PTHR11138 3 298 2.1E-103 T 21-04-2016 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 Gene3D G3DSA:3.10.25.10 208 310 1.9E-32 T 21-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 2 302 33.64 T 21-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 3 303 1.5E-95 T 21-04-2016 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 133 156 - T 21-04-2016 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 Gene3D G3DSA:3.40.50.170 3 205 1.4E-63 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 SUPERFAMILY SSF50486 205 303 3.61E-31 T 21-04-2016 IPR011034 Formyl transferase, C-terminal-like GO:0003824 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 Pfam PF00551 Formyl transferase 3 180 3.3E-37 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 Pfam PF02911 Formyl transferase, C-terminal domain 204 299 6.9E-28 T 21-04-2016 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS06930 f2ee9d8909ac9a23d2974aff3c3e26c4 311 SUPERFAMILY SSF53328 3 203 3.53E-61 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Gene3D G3DSA:3.40.1360.10 243 361 1.5E-40 T 21-04-2016 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Hamap MF_00974 DNA primase [dnaG]. 2 593 26.377 T 21-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Gene3D G3DSA:3.90.980.10 113 242 9.6E-36 T 21-04-2016 IPR013264 DNA primase, catalytic core, N-terminal HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 PIRSF PIRSF002811 1 603 3.9E-169 T 21-04-2016 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 SMART SM00400 34 88 4.0E-32 T 21-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 PANTHER PTHR30313 1 603 8.2E-124 T 21-04-2016 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Pfam PF01807 CHC2 zinc finger 5 97 6.2E-37 T 21-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Pfam PF13155 Toprim-like 264 347 9.9E-18 T 21-04-2016 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 SMART SM00493 261 332 4.2E-15 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 TIGRFAM TIGR01391 dnaG: DNA primase 3 416 5.0E-137 T 21-04-2016 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 SUPERFAMILY SSF56731 113 423 2.62E-90 T 21-04-2016 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 SUPERFAMILY SSF57783 1 95 2.38E-33 T 21-04-2016 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Gene3D G3DSA:3.90.580.10 2 95 5.4E-37 T 21-04-2016 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 HSISS4_RS07145 7973856dd5a38da486aec89d7fad6bcc 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 254 1.0E-35 T 21-04-2016 IPR013264 DNA primase, catalytic core, N-terminal HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Pfam PF08264 Anticodon-binding domain of tRNA 678 832 1.3E-27 T 21-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Gene3D G3DSA:3.40.50.620 394 631 6.2E-139 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Gene3D G3DSA:3.40.50.620 16 203 6.2E-139 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 520 533 5.6E-27 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 228 251 5.6E-27 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 5.6E-27 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 554 563 5.6E-27 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 392 407 5.6E-27 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 834 7.4E-282 T 21-04-2016 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5|Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Gene3D G3DSA:3.90.740.10 205 382 1.0E-45 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 SUPERFAMILY SSF50677 202 394 2.93E-42 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 SUPERFAMILY SSF52374 1 200 2.69E-151 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 SUPERFAMILY SSF52374 394 641 2.69E-151 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946 275 866 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946 885 917 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946 5 249 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 19.327 T 21-04-2016 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 634 1.3E-197 T 21-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946:SF11 275 866 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946:SF11 885 917 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 PANTHER PTHR11946:SF11 5 249 0.0 T 21-04-2016 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Gene3D G3DSA:1.10.730.10 634 818 5.0E-43 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 SUPERFAMILY SSF47323 645 917 1.48E-73 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03670 f599a2223d3e0df2f9710887e210e414 932 Pfam PF06827 Zinc finger found in FPG and IleRS 885 913 1.5E-5 T 21-04-2016 IPR010663 Zinc finger, FPG/IleRS-type HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 SUPERFAMILY SSF69287 1 73 1.57E-18 T 21-04-2016 IPR004029 UreE urease accessory, N-terminal HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 Gene3D G3DSA:3.30.70.790 76 143 3.2E-16 T 21-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 Pfam PF05194 UreE urease accessory protein, C-terminal domain 76 127 5.7E-7 T 21-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 PANTHER PTHR33620 62 149 2.3E-13 T 21-04-2016 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 Gene3D G3DSA:2.60.260.20 1 71 4.4E-20 T 21-04-2016 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 Pfam PF02814 UreE urease accessory protein, N-terminal domain 16 67 2.8E-14 T 21-04-2016 IPR004029 UreE urease accessory, N-terminal HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 PANTHER PTHR33620:SF2 62 149 2.3E-13 T 21-04-2016 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 SUPERFAMILY SSF69737 76 141 1.7E-13 T 21-04-2016 IPR007864 Urease accessory protein UreE, C-terminal domain GO:0006461|GO:0016151|GO:0019627 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 SMART SM00988 6 69 5.4E-16 T 21-04-2016 IPR004029 UreE urease accessory, N-terminal HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 PIRSF PIRSF036402 1 150 2.5E-40 T 21-04-2016 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 HSISS4_RS01325 34f5927bbcc3cea2886f1922fd0382bf 150 Hamap MF_00822 Urease accessory protein UreE [ureE]. 1 148 18.303 T 21-04-2016 IPR012406 Urease accessory protein UreE GO:0005737|GO:0006457|GO:0016151|GO:0018307 HSISS4_RS03825 4fa54759a248b82a3ea9f078234e204e 197 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 11 195 2.0E-99 T 21-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HSISS4_RS03825 4fa54759a248b82a3ea9f078234e204e 197 Gene3D G3DSA:2.60.120.10 17 191 8.3E-55 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS03825 4fa54759a248b82a3ea9f078234e204e 197 SUPERFAMILY SSF51182 17 191 4.65E-52 T 21-04-2016 IPR011051 RmlC-like cupin domain HSISS4_RS03825 4fa54759a248b82a3ea9f078234e204e 197 PANTHER PTHR21047 2 189 1.1E-42 T 21-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HSISS4_RS03825 4fa54759a248b82a3ea9f078234e204e 197 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 17 188 1.1E-39 T 21-04-2016 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 814 879 2.9E-17 T 21-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PANTHER PTHR11946:SF5 1 790 0.0 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PANTHER PTHR11946:SF5 810 872 0.0 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 SUPERFAMILY SSF46589 814 877 7.32E-16 T 21-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 TIGRFAM TIGR00422 valS: valine--tRNA ligase 7 861 0.0 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 46 57 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 SUPERFAMILY SSF52374 5 195 1.73E-140 T 21-04-2016 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 SUPERFAMILY SSF52374 343 570 1.73E-140 T 21-04-2016 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Gene3D G3DSA:1.10.287.380 807 866 9.8E-6 T 21-04-2016 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 SUPERFAMILY SSF47323 571 829 2.24E-66 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Gene3D G3DSA:3.90.740.10 197 339 2.5E-50 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PRINTS PR00986 Valyl-tRNA synthetase signature 472 490 7.6E-37 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PRINTS PR00986 Valyl-tRNA synthetase signature 233 250 7.6E-37 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PRINTS PR00986 Valyl-tRNA synthetase signature 39 50 7.6E-37 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PRINTS PR00986 Valyl-tRNA synthetase signature 348 361 7.6E-37 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PRINTS PR00986 Valyl-tRNA synthetase signature 440 461 7.6E-37 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Gene3D G3DSA:1.10.730.10 560 745 3.1E-56 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 436 560 1.0E-54 T 21-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 430 1.3E-163 T 21-04-2016 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PANTHER PTHR11946 1 790 0.0 T 21-04-2016 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 PANTHER PTHR11946 810 872 0.0 T 21-04-2016 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Pfam PF08264 Anticodon-binding domain of tRNA 610 755 3.2E-41 T 21-04-2016 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Hamap MF_02004 Valine--tRNA ligase [valS]. 5 879 15.742 T 21-04-2016 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: REACT_71 HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Gene3D G3DSA:3.40.50.620 8 196 1.8E-140 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 Gene3D G3DSA:3.40.50.620 343 559 1.8E-140 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS02230 777883af31b71291650cdcd8a74a4d08 883 SUPERFAMILY SSF50677 193 344 1.19E-61 T 21-04-2016 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 Reactome: REACT_71 HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 Gene3D G3DSA:3.10.180.10 153 277 5.8E-17 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 Gene3D G3DSA:3.10.180.10 11 134 8.8E-26 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 SUPERFAMILY SSF54593 9 158 1.55E-33 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 122 2.0E-11 T 21-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 PANTHER PTHR10374 1 168 2.6E-46 T 21-04-2016 HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 PANTHER PTHR10374:SF14 1 168 2.6E-46 T 21-04-2016 HSISS4_RS06290 e4ae83a02e3693b247a87562cd91f2d1 285 SUPERFAMILY SSF54593 163 280 6.23E-20 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PANTHER PTHR22807 1 439 7.4E-110 T 21-04-2016 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 Pfam PF01029 NusB family 8 130 1.1E-26 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 Gene3D G3DSA:3.40.50.150 235 439 4.6E-57 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 Gene3D G3DSA:1.10.940.10 6 159 1.7E-42 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 21-04-2016 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 SUPERFAMILY SSF53335 147 439 1.21E-63 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PANTHER PTHR22807:SF30 1 439 7.4E-110 T 21-04-2016 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 SUPERFAMILY SSF48013 5 134 3.53E-32 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 1.5E-30 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 1.5E-30 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 1.5E-30 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 1.5E-30 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 421 438 1.5E-30 T 21-04-2016 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 2.3E-53 T 21-04-2016 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS06925 978c7758ecad13610f93006fc1e0d6ad 440 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 12 440 2.0E-109 T 21-04-2016 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 SUPERFAMILY SSF53448 4 252 3.89E-64 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 40.727 T 21-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 SUPERFAMILY SSF51161 256 445 1.51E-45 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 PANTHER PTHR22572:SF115 4 448 1.7E-214 T 21-04-2016 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Gene3D G3DSA:2.160.10.10 333 449 3.1E-34 T 21-04-2016 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 352 381 0.0013 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 298 0.0019 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 316 351 3.3E-6 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 427 3.3E-5 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Pfam PF12804 MobA-like NTP transferase domain 5 140 9.2E-20 T 21-04-2016 IPR025877 MobA-like NTP transferase HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Gene3D G3DSA:2.160.10.10 245 332 5.6E-16 T 21-04-2016 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 PANTHER PTHR22572 4 448 1.7E-214 T 21-04-2016 HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 Gene3D G3DSA:3.90.550.10 1 244 1.5E-78 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS02635 ebdfdbbc71a543adde20598799ca2a06 460 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 452 1.4E-173 T 21-04-2016 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587|UniPathway: UPA00113|UniPathway: UPA00113|UniPathway: UPA00973 HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 Gene3D G3DSA:3.30.830.10 1 228 2.1E-67 T 21-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 Pfam PF05193 Peptidase M16 inactive domain 189 349 7.3E-18 T 21-04-2016 IPR007863 Peptidase M16, C-terminal HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 SUPERFAMILY SSF63411 6 211 5.59E-9 T 21-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 Gene3D G3DSA:3.30.830.10 236 403 2.7E-29 T 21-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 SUPERFAMILY SSF63411 240 404 6.7E-30 T 21-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HSISS4_RS09675 09d749460dc5b369e9029150fc31ea4b 416 PANTHER PTHR11851 237 404 1.4E-17 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 SUPERFAMILY SSF51998 169 701 7.94E-173 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 TIGRFAM TIGR04170 RNR_1b_NrdE: ribonucleoside-diphosphate reductase, class 1b, alpha subunit 11 719 0.0 T 21-04-2016 IPR026459 Ribonucleotide reductase, class 1b, subunit NrdE KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Gene3D G3DSA:3.20.70.20 80 291 1.1E-56 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Gene3D G3DSA:3.20.70.20 569 676 1.1E-56 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Gene3D G3DSA:3.20.70.20 344 507 1.1E-56 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 558 580 - T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PANTHER PTHR11573 8 701 4.3E-223 T 21-04-2016 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Pfam PF08343 Ribonucleotide reductase N-terminal 11 91 1.0E-28 T 21-04-2016 IPR013554 Ribonucleotide reductase N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Pfam PF02867 Ribonucleotide reductase, barrel domain 170 698 3.3E-140 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 245 264 1.0E-22 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 459 481 1.0E-22 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 487 510 1.0E-22 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 376 387 1.0E-22 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 PRINTS PR01183 Ribonucleotide reductase large chain signature 569 596 1.0E-22 T 21-04-2016 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 93 165 1.4E-11 T 21-04-2016 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 96 701 7.0E-149 T 21-04-2016 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS03680 098c68878bee917f5870c9b65489d9cc 719 SUPERFAMILY SSF48168 22 168 1.44E-42 T 21-04-2016 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 SMART SM00228 307 393 2.0E-9 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 SUPERFAMILY SSF50156 335 404 4.34E-16 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 Gene3D G3DSA:2.40.10.10 57 181 1.5E-27 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 Gene3D G3DSA:2.40.10.10 184 308 4.3E-42 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 SUPERFAMILY SSF50494 57 299 1.94E-55 T 21-04-2016 IPR009003 Peptidase S1, PA clan HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 Pfam PF13365 Trypsin-like peptidase domain 118 263 6.0E-30 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PANTHER PTHR22939 9 79 7.7E-100 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 Gene3D G3DSA:2.30.42.10 309 406 9.9E-20 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 256 273 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 151 171 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 234 251 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 192 216 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 351 363 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PRINTS PR00834 HtrA/DegQ protease family signature 130 142 1.1E-36 T 21-04-2016 IPR001940 Peptidase S1C GO:0004252|GO:0006508 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 Pfam PF13180 PDZ domain 307 402 6.4E-20 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PANTHER PTHR22939:SF79 100 405 7.7E-100 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PANTHER PTHR22939:SF79 9 79 7.7E-100 T 21-04-2016 HSISS4_RS09745 4cb4f83da7c29331748887bd41e824f0 411 PANTHER PTHR22939 100 405 7.7E-100 T 21-04-2016 HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 Gene3D G3DSA:3.40.50.300 4 246 2.5E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 PANTHER PTHR24220:SF585 7 249 2.6E-124 T 21-04-2016 HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 PANTHER PTHR24220 7 249 2.6E-124 T 21-04-2016 HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 SMART SM00382 30 224 2.8E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 SUPERFAMILY SSF52540 3 240 4.67E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 Pfam PF00005 ABC transporter 21 177 2.2E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 6 252 3.2E-119 T 21-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HSISS4_RS04875 bc337ef153ce04c68f91d14474478bca 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00175 f55cc117beaffa690e51bc846b65e8bc 276 PIRSF PIRSF038471 1 275 2.9E-44 T 21-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HSISS4_RS00175 f55cc117beaffa690e51bc846b65e8bc 276 PANTHER PTHR34138:SF1 1 272 4.1E-38 T 21-04-2016 HSISS4_RS00175 f55cc117beaffa690e51bc846b65e8bc 276 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 15 272 2.5E-32 T 21-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HSISS4_RS00175 f55cc117beaffa690e51bc846b65e8bc 276 Pfam PF04085 rod shape-determining protein MreC 125 272 2.5E-30 T 21-04-2016 IPR007221 Rod shape-determining protein MreC GO:0008360 HSISS4_RS00175 f55cc117beaffa690e51bc846b65e8bc 276 PANTHER PTHR34138 1 272 4.1E-38 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 68 1.1E-17 T 21-04-2016 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Pfam PF00702 haloacid dehalogenase-like hydrolase 428 642 2.0E-44 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Pfam PF00403 Heavy-metal-associated domain 5 66 2.2E-15 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 ProSitePatterns PS01229 Hypothetical cof family signature 2. 628 650 - T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 144 738 5.2E-186 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF55008 2 73 1.19E-22 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00941 Cadmium-transporting ATPase signature 296 312 8.5E-9 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00941 Cadmium-transporting ATPase signature 315 329 8.5E-9 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00941 Cadmium-transporting ATPase signature 215 235 8.5E-9 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00941 Cadmium-transporting ATPase signature 6 15 8.5E-9 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00941 Cadmium-transporting ATPase signature 235 251 8.5E-9 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 433 439 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PANTHER PTHR24093:SF50 1 741 1.2E-251 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 162 737 5.4E-191 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 202 705 3.2E-99 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Pfam PF00122 E1-E2 ATPase 201 422 2.2E-70 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF81653 234 330 1.15E-28 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Gene3D G3DSA:3.40.1110.10 457 555 3.2E-19 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 21-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF56784 429 449 1.6E-60 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF56784 486 735 1.6E-60 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF81665 190 234 7.06E-11 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF81665 677 706 7.06E-11 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 SUPERFAMILY SSF81665 331 424 7.06E-11 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Gene3D G3DSA:3.40.50.1000 402 447 3.2E-57 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Gene3D G3DSA:3.40.50.1000 556 697 3.2E-57 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 564 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 575 585 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 647 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 651 663 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 280 294 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 431 445 4.3E-30 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Gene3D G3DSA:3.30.70.100 2 84 2.4E-26 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 PANTHER PTHR24093 1 741 1.2E-251 T 21-04-2016 HSISS4_RS07630 bb53766d662fff708f0db7f9b35d73ae 742 Gene3D G3DSA:2.70.150.10 191 331 5.6E-34 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 Pfam PF05167 Uncharacterised ACR (DUF711) 12 408 5.1E-167 T 21-04-2016 IPR007841 Uncharacterised protein family UPF0210 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 Gene3D G3DSA:3.20.70.20 1 445 7.1E-214 T 21-04-2016 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 PANTHER PTHR37560:SF2 1 445 7.1E-237 T 21-04-2016 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 Hamap MF_01221 UPF0210 protein . 1 445 51.558 T 21-04-2016 IPR007841 Uncharacterised protein family UPF0210 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 PANTHER PTHR37560 1 445 7.1E-237 T 21-04-2016 HSISS4_RS00645 1bcef196ad30b66d523e9ffb9b42f317 445 SUPERFAMILY SSF51998 2 440 5.68E-176 T 21-04-2016 HSISS4_RS02085 238df9346898e2962ca988dcbc8491e3 319 PIRSF PIRSF007487 1 319 1.9E-113 T 21-04-2016 IPR021176 Competence-induced protein CoiA-like, bacterial HSISS4_RS02085 238df9346898e2962ca988dcbc8491e3 319 Pfam PF06054 Competence protein CoiA-like family 1 269 2.8E-37 T 21-04-2016 IPR010330 Competence-induced protein CoiA-like HSISS4_RS02085 238df9346898e2962ca988dcbc8491e3 319 PANTHER PTHR41265 1 313 5.1E-52 T 21-04-2016 HSISS4_RS02085 238df9346898e2962ca988dcbc8491e3 319 PANTHER PTHR41265:SF1 1 313 5.1E-52 T 21-04-2016 HSISS4_RS01180 b31d38adccd43437b17e842552314039 92 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 21-04-2016 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HSISS4_RS01180 b31d38adccd43437b17e842552314039 92 Gene3D G3DSA:3.30.70.100 1 89 3.9E-24 T 21-04-2016 HSISS4_RS01180 b31d38adccd43437b17e842552314039 92 PANTHER PTHR10029 4 89 5.4E-17 T 21-04-2016 HSISS4_RS01180 b31d38adccd43437b17e842552314039 92 SUPERFAMILY SSF54975 2 90 2.83E-21 T 21-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HSISS4_RS01180 b31d38adccd43437b17e842552314039 92 Pfam PF00708 Acylphosphatase 1 90 1.7E-22 T 21-04-2016 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 PANTHER PTHR21000 1 571 0.0 T 21-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 Pfam PF00920 Dehydratase family 33 551 1.5E-221 T 21-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 121 131 - T 21-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 463 474 - T 21-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 555 45.614 T 21-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 SUPERFAMILY SSF52016 375 554 1.8E-59 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 PANTHER PTHR21000:SF11 1 571 0.0 T 21-04-2016 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 SUPERFAMILY SSF143975 1 374 1.27E-135 T 21-04-2016 HSISS4_RS09120 425061c04c8ecac2817016b03fee3192 573 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 15 553 1.9E-235 T 21-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 21-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PANTHER PTHR22912 1 450 5.5E-242 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PANTHER PTHR22912:SF106 1 450 5.5E-242 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PIRSF PIRSF000350 1 446 7.1E-76 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Gene3D G3DSA:3.30.390.30 330 450 5.6E-41 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 318 4.0E-68 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Gene3D G3DSA:3.50.50.60 3 147 5.6E-44 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Gene3D G3DSA:3.50.50.60 247 329 1.4E-26 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 SUPERFAMILY SSF51905 2 359 1.08E-59 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.9E-28 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.9E-28 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 1.9E-28 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 283 305 1.9E-28 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.9E-28 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 SUPERFAMILY SSF55424 336 450 1.24E-34 T 21-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Gene3D G3DSA:3.50.50.60 148 246 6.6E-34 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 305 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 8.6E-65 T 21-04-2016 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 TIGRFAM TIGR01421 gluta_reduc_1: glutathione-disulfide reductase 3 450 9.7E-216 T 21-04-2016 IPR006322 Glutathione reductase, eukaryote/bacterial GO:0004362|GO:0006749|GO:0050660|GO:0050661|GO:0055114 KEGG: 00480+1.8.1.7|MetaCyc: PWY-4081 HSISS4_RS01870 a8a4067689d6c7843a9eaeaff29ebc80 450 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 449 1.7E-34 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 9 685 2.5E-259 T 21-04-2016 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 KEGG: 00900+3.4.22.- HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 PANTHER PTHR24221 144 667 2.2E-131 T 21-04-2016 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 SUPERFAMILY SSF90123 155 460 3.4E-64 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 SMART SM00382 503 686 7.0E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Pfam PF00005 ABC transporter 494 640 1.6E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Gene3D G3DSA:3.90.70.10 10 138 7.2E-17 T 21-04-2016 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Pfam PF00664 ABC transporter transmembrane region 167 436 1.0E-53 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 ProSitePatterns PS00211 ABC transporters family signature. 612 626 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Gene3D G3DSA:1.20.1560.10 155 460 1.8E-70 T 21-04-2016 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Pfam PF03412 Peptidase C39 family 3 139 4.9E-42 T 21-04-2016 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 Gene3D G3DSA:3.40.50.300 478 686 9.9E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01290 d42751ddacf785ba3a5d031e1fe57d30 698 SUPERFAMILY SSF52540 476 686 2.15E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 SUPERFAMILY SSF54373 209 299 9.68E-11 T 21-04-2016 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 Gene3D G3DSA:3.30.9.10 196 299 4.8E-14 T 21-04-2016 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 SUPERFAMILY SSF51905 1 209 7.38E-27 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 SUPERFAMILY SSF51905 300 357 7.38E-27 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 Pfam PF01266 FAD dependent oxidoreductase 2 339 2.0E-40 T 21-04-2016 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 PANTHER PTHR13847:SF211 5 360 7.6E-109 T 21-04-2016 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 Gene3D G3DSA:3.50.50.60 136 195 1.9E-34 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 Gene3D G3DSA:3.50.50.60 300 355 1.9E-34 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 Gene3D G3DSA:3.50.50.60 1 79 1.9E-34 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03810 22b58a2778284e3babe27a104b962177 362 PANTHER PTHR13847 5 360 7.6E-109 T 21-04-2016 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SMART SM00642 593 983 2.3E-8 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357 991 1040 4.2E-133 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357 1057 1140 4.2E-133 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357 850 960 4.2E-133 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357 444 828 4.2E-133 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Gene3D G3DSA:3.20.20.80 593 1035 1.2E-109 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SUPERFAMILY SSF51445 986 1035 2.52E-102 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SUPERFAMILY SSF51445 565 951 2.52E-102 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357:SF99 991 1040 4.2E-133 T 21-04-2016 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357:SF99 1057 1140 4.2E-133 T 21-04-2016 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357:SF99 850 960 4.2E-133 T 21-04-2016 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 PANTHER PTHR10357:SF99 444 828 4.2E-133 T 21-04-2016 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF00746 Gram positive anchor 1201 1235 6.4E-6 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 TIGRFAM TIGR02102 pullulan_Gpos: pullulanase, extracellular 134 1235 0.0 T 21-04-2016 IPR011838 Pullulanase, extracellular HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 5 38 1.4E-9 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SUPERFAMILY SSF81296 448 550 2.24E-13 T 21-04-2016 IPR014756 Immunoglobulin E-set HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF04650 YSIRK type signal peptide 10 34 2.0E-8 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1205 1235 1.6E-5 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SUPERFAMILY SSF49452 136 241 6.54E-27 T 21-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF03714 Bacterial pullanase-associated domain 248 348 8.5E-14 T 21-04-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF03714 Bacterial pullanase-associated domain 138 235 5.6E-13 T 21-04-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF00128 Alpha amylase, catalytic domain 619 721 2.5E-14 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Gene3D G3DSA:2.60.40.10 452 592 8.7E-18 T 21-04-2016 IPR013783 Immunoglobulin-like fold HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 453 540 5.9E-10 T 21-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 HSISS4_RS04780 8ab5903de23ed87725f32791565c30f4 1237 SUPERFAMILY SSF49452 243 352 7.85E-31 T 21-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 SUPERFAMILY SSF52540 1 217 1.89E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 Pfam PF00005 ABC transporter 17 159 1.1E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 SMART SM00382 26 216 3.3E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 PANTHER PTHR24220 3 212 2.8E-87 T 21-04-2016 HSISS4_RS06255 24308fd87a4f76cae9413545167e37c1 226 Gene3D G3DSA:3.40.50.300 1 217 5.6E-70 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03340 bb56db377f2a5d03174eecb02deb8510 132 PANTHER PTHR40070:SF1 1 127 1.1E-22 T 21-04-2016 HSISS4_RS03340 bb56db377f2a5d03174eecb02deb8510 132 PANTHER PTHR40070 1 127 1.1E-22 T 21-04-2016 HSISS4_RS03340 bb56db377f2a5d03174eecb02deb8510 132 Pfam PF06103 Bacterial protein of unknown function (DUF948) 4 91 1.6E-26 T 21-04-2016 IPR009293 Uncharacterised protein family UPF0478 HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 PANTHER PTHR37294:SF1 1 313 2.6E-113 T 21-04-2016 HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 Gene3D G3DSA:2.40.50.140 18 82 1.4E-4 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 Pfam PF01966 HD domain 160 278 2.0E-7 T 21-04-2016 IPR006674 HD domain HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 Gene3D G3DSA:1.10.3210.10 154 279 1.3E-5 T 21-04-2016 IPR006674 HD domain HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 PANTHER PTHR37294 1 313 2.6E-113 T 21-04-2016 HSISS4_RS08605 7be15cba3db9f83db9f884645f4dea8c 313 SUPERFAMILY SSF109604 142 280 2.69E-11 T 21-04-2016 HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 PANTHER PTHR31715 3 204 4.2E-105 T 21-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 SUPERFAMILY SSF52540 2 197 9.57E-33 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 Gene3D G3DSA:3.40.50.300 4 196 6.7E-18 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 6 202 4.9E-90 T 21-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 Hamap MF_01389 Urease accessory protein UreG [ureG]. 4 202 41.721 T 21-04-2016 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 178 1.7E-40 T 21-04-2016 IPR003495 CobW/HypB/UreG, nucleotide-binding domain HSISS4_RS01335 0e0eca15453ea35279901c3e6073e406 204 PIRSF PIRSF005624 1 202 2.9E-46 T 21-04-2016 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 2 437 34.521 T 21-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 PANTHER PTHR23135:SF5 1 426 2.9E-147 T 21-04-2016 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Gene3D G3DSA:3.90.190.20 299 434 1.6E-42 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 SUPERFAMILY SSF53244 296 433 2.52E-36 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 SUPERFAMILY SSF51984 3 87 4.12E-18 T 21-04-2016 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Gene3D G3DSA:3.40.50.720 3 88 5.6E-25 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 SUPERFAMILY SSF53623 90 295 2.62E-54 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Pfam PF02875 Mur ligase family, glutamate ligase domain 298 378 1.4E-15 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 PANTHER PTHR23135 1 426 2.9E-147 T 21-04-2016 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Pfam PF01225 Mur ligase family, catalytic domain 4 103 2.1E-25 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Pfam PF08245 Mur ligase middle domain 108 275 4.1E-21 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 Gene3D G3DSA:3.40.1190.10 92 298 7.7E-58 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01155 c7ed5e7c24e36d8b52e95fd52858cbe2 442 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 5 427 2.5E-119 T 21-04-2016 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 PANTHER PTHR11659 2 479 1.9E-245 T 21-04-2016 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 Pfam PF02637 GatB domain 327 474 3.0E-47 T 21-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 143 157 - T 21-04-2016 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 SMART SM00845 327 474 2.2E-63 T 21-04-2016 IPR018027 Asn/Gln amidotransferase GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 474 7.3E-165 T 21-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 SUPERFAMILY SSF89095 296 400 1.57E-33 T 21-04-2016 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 PANTHER PTHR11659:SF0 2 479 1.9E-245 T 21-04-2016 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 475 37.122 T 21-04-2016 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 SUPERFAMILY SSF55931 4 295 2.29E-118 T 21-04-2016 HSISS4_RS07865 df120d6ce4bdf9ad08e60b993811149d 480 Pfam PF02934 GatB/GatE catalytic domain 5 288 2.0E-109 T 21-04-2016 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 356 48.098 T 21-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00097 Anthranilate synthase component II signature 215 224 2.6E-7 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00097 Anthranilate synthase component II signature 327 340 2.6E-7 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00097 Anthranilate synthase component II signature 242 253 2.6E-7 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 353 3.3E-146 T 21-04-2016 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 SUPERFAMILY SSF52317 140 353 5.24E-60 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 Gene3D G3DSA:3.40.50.880 157 355 1.0E-68 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 1.8E-54 T 21-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 242 253 4.8E-12 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 4.8E-12 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00096 Glutamine amidotransferase superfamily signature 215 224 4.8E-12 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 242 258 2.4E-35 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 259 276 2.4E-35 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 284 295 2.4E-35 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 173 187 2.4E-35 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 212 226 2.4E-35 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 Pfam PF00117 Glutamine amidotransferase class-I 175 350 2.1E-46 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 SUPERFAMILY SSF52021 2 146 7.85E-58 T 21-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 SMART SM01097 2 132 2.5E-91 T 21-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 PANTHER PTHR11405 2 357 1.7E-218 T 21-04-2016 HSISS4_RS02465 7e1cb9364f8ec4edec5b7c8c752b6bb5 362 Gene3D G3DSA:3.50.30.20 2 145 1.3E-62 T 21-04-2016 IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|UniPathway: UPA00068|UniPathway: UPA00070 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 Pfam PF00128 Alpha amylase, catalytic domain 310 399 3.8E-8 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 SUPERFAMILY SSF51445 253 683 4.09E-101 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 SUPERFAMILY SSF81296 129 241 7.23E-17 T 21-04-2016 IPR014756 Immunoglobulin E-set HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 SUPERFAMILY SSF49452 1 100 3.6E-23 T 21-04-2016 IPR013784 Carbohydrate-binding-like fold GO:0030246 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 Gene3D G3DSA:2.60.40.10 130 239 4.6E-18 T 21-04-2016 IPR013783 Immunoglobulin-like fold HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 Gene3D G3DSA:3.20.20.80 255 683 9.3E-83 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 Pfam PF03714 Bacterial pullanase-associated domain 5 98 1.9E-9 T 21-04-2016 IPR005323 Bacterial pullanase-associated domain GO:0005975|GO:0030246 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357:SF99 141 491 4.1E-115 T 21-04-2016 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357:SF99 509 628 4.1E-115 T 21-04-2016 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357:SF99 644 707 4.1E-115 T 21-04-2016 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 125 714 1.1E-209 T 21-04-2016 IPR011840 Pullulanase, type I HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 SMART SM00642 270 674 2.2E-6 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 136 225 4.3E-11 T 21-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357 141 491 4.1E-115 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357 509 628 4.1E-115 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS06860 c3e9fd2ad3ddeb0360044bfcdb6dc466 731 PANTHER PTHR10357 644 707 4.1E-115 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 1.2E-15 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 PANTHER PTHR30363 1 248 1.1E-78 T 21-04-2016 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 SMART SM01134 74 231 2.3E-62 T 21-04-2016 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 Gene3D G3DSA:1.10.10.10 1 56 2.2E-4 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 SUPERFAMILY SSF46785 4 65 2.25E-10 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 Gene3D G3DSA:3.40.50.1360 78 215 3.7E-13 T 21-04-2016 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 Pfam PF00455 DeoR C terminal sensor domain 76 228 1.5E-44 T 21-04-2016 IPR014036 DeoR C-terminal sensor domain HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 25 39 1.4E-5 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 39 57 1.4E-5 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 SUPERFAMILY SSF100950 75 228 4.02E-32 T 21-04-2016 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 SMART SM00420 6 59 4.4E-17 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01855 310f8ce980afe27bc376327a313198aa 248 PANTHER PTHR30363:SF4 1 248 1.1E-78 T 21-04-2016 HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 Gene3D G3DSA:3.10.129.10 151 242 9.6E-26 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 Pfam PF01643 Acyl-ACP thioesterase 2 243 1.0E-81 T 21-04-2016 IPR002864 Acyl-ACP thioesterase GO:0006633|GO:0016790 HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 PANTHER PTHR31727 51 212 6.4E-36 T 21-04-2016 HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 Gene3D G3DSA:3.10.129.10 2 144 1.5E-35 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 SUPERFAMILY SSF54637 149 241 2.58E-22 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS03850 1eed7a9e2ae62bca90099c47831fd983 247 SUPERFAMILY SSF54637 1 146 8.18E-40 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 SUPERFAMILY SSF51569 2 290 2.01E-94 T 21-04-2016 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 PANTHER PTHR10277:SF9 2 509 2.3E-213 T 21-04-2016 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 510 39.114 T 21-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 496 2.5E-29 T 21-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 21-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 SUPERFAMILY SSF110921 394 496 1.01E-14 T 21-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 21-04-2016 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 PANTHER PTHR10277 2 509 2.3E-213 T 21-04-2016 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 Gene3D G3DSA:3.20.20.70 2 345 1.5E-137 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 Pfam PF00682 HMGL-like 3 272 3.8E-95 T 21-04-2016 IPR000891 Pyruvate carboxyltransferase GO:0003824 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 496 2.2E-189 T 21-04-2016 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS04120 1eca5c2e3662b2b866bf6c55c14c138d 518 SMART SM00917 368 501 6.8E-26 T 21-04-2016 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871|UniPathway: UPA00048 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 163 69.879 T 21-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 25 136 2.4E-54 T 21-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 Gene3D G3DSA:3.30.1130.10 16 148 1.3E-56 T 21-04-2016 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 Pfam PF14489 QueF-like protein 60 138 9.1E-35 T 21-04-2016 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 PANTHER PTHR34354 1 149 4.8E-67 T 21-04-2016 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 PIRSF PIRSF027377 5 145 1.3E-62 T 21-04-2016 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 PANTHER PTHR34354:SF1 1 149 4.8E-67 T 21-04-2016 HSISS4_RS05555 43a25314f36e153780190417367ec4c1 163 SUPERFAMILY SSF55620 25 133 2.89E-28 T 21-04-2016 HSISS4_RS03230 1ee296cbb7b53351a685eb60afd96387 357 PANTHER PTHR11516:SF25 37 357 1.5E-146 T 21-04-2016 HSISS4_RS03230 1ee296cbb7b53351a685eb60afd96387 357 Gene3D G3DSA:3.40.50.970 31 357 9.3E-125 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS03230 1ee296cbb7b53351a685eb60afd96387 357 Pfam PF00676 Dehydrogenase E1 component 51 346 1.3E-92 T 21-04-2016 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 HSISS4_RS03230 1ee296cbb7b53351a685eb60afd96387 357 SUPERFAMILY SSF52518 16 357 3.58E-98 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS03230 1ee296cbb7b53351a685eb60afd96387 357 PANTHER PTHR11516 37 357 1.5E-146 T 21-04-2016 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 Pfam PF14278 Transcriptional regulator C-terminal region 81 156 2.4E-7 T 21-04-2016 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 61 2.7E-9 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 SUPERFAMILY SSF46689 5 72 1.69E-16 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 Gene3D G3DSA:1.10.357.10 10 174 3.8E-21 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 PANTHER PTHR30328 1 174 1.1E-49 T 21-04-2016 HSISS4_RS05165 20245aeb1d03cd96957c56191014a461 179 PANTHER PTHR30328:SF20 1 174 1.1E-49 T 21-04-2016 HSISS4_RS05545 d49f5dd304fd75f1eb90fc56637ab570 256 PANTHER PTHR41386:SF1 22 205 2.1E-34 T 21-04-2016 HSISS4_RS05545 d49f5dd304fd75f1eb90fc56637ab570 256 Pfam PF06210 Protein of unknown function (DUF1003) 114 211 7.3E-36 T 21-04-2016 IPR010406 Protein of unknown function DUF1003 HSISS4_RS05545 d49f5dd304fd75f1eb90fc56637ab570 256 PANTHER PTHR41386 22 205 2.1E-34 T 21-04-2016 HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 PANTHER PTHR24220:SF66 5 247 1.1E-58 T 21-04-2016 HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 Gene3D G3DSA:3.40.50.300 3 228 3.4E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 SMART SM00382 28 234 8.2E-8 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 SUPERFAMILY SSF52540 1 228 2.01E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 Pfam PF00005 ABC transporter 29 164 2.4E-23 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05215 c9abbbadc657c752b02370d6280bb6ba 266 PANTHER PTHR24220 5 247 1.1E-58 T 21-04-2016 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PRINTS PR01607 Apyrase family signature 476 499 3.0E-19 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PRINTS PR01607 Apyrase family signature 293 310 3.0E-19 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PRINTS PR01607 Apyrase family signature 115 133 3.0E-19 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PRINTS PR01607 Apyrase family signature 573 592 3.0E-19 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 SUPERFAMILY SSF55816 415 624 2.35E-42 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 Pfam PF00149 Calcineurin-like phosphoesterase 118 342 1.7E-5 T 21-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 Gene3D G3DSA:3.60.21.10 113 410 1.6E-73 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 ProSitePatterns PS00785 5'-nucleotidase signature 1. 117 129 - T 21-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 ProSitePatterns PS00786 5'-nucleotidase signature 2. 188 199 - T 21-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PANTHER PTHR11575 646 653 1.9E-94 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 PANTHER PTHR11575 111 616 1.9E-94 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 SUPERFAMILY SSF56300 115 409 4.64E-64 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 Gene3D G3DSA:3.90.780.10 415 620 5.3E-46 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS04980 4e54ce881e74e880c3d30ce1e9dc1e13 748 Pfam PF02872 5'-nucleotidase, C-terminal domain 418 598 2.2E-35 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 PANTHER PTHR37825 2 362 6.4E-95 T 21-04-2016 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 Hamap MF_01539 UPF0348 protein . 2 361 34.373 T 21-04-2016 IPR008513 Uncharacterised protein family UPF0348 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 Gene3D G3DSA:3.40.50.620 1 214 4.2E-74 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 PANTHER PTHR37825:SF1 2 362 6.4E-95 T 21-04-2016 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 SUPERFAMILY SSF52374 10 138 1.19E-16 T 21-04-2016 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 SUPERFAMILY SSF52374 186 212 1.19E-16 T 21-04-2016 HSISS4_RS07805 1f4d1111744fc52c0d921c5abb79b3ba 363 Pfam PF05636 HIGH Nucleotidyl Transferase 1 348 5.0E-109 T 21-04-2016 IPR008513 Uncharacterised protein family UPF0348 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 Pfam PF00591 Glycosyl transferase family, a/b domain 75 323 1.9E-82 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 64 2.6E-16 T 21-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 Gene3D G3DSA:1.20.970.10 1 65 2.1E-22 T 21-04-2016 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 3 332 34.637 T 21-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 331 1.2E-104 T 21-04-2016 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18|UniPathway: UPA00035 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 Gene3D G3DSA:3.40.1030.10 73 333 1.2E-93 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 SUPERFAMILY SSF52418 73 331 7.46E-82 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 PANTHER PTHR11922:SF5 72 332 2.3E-105 T 21-04-2016 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 PANTHER PTHR11922 72 332 2.3E-105 T 21-04-2016 HSISS4_RS07665 704e32b1c5200ed3641078a5bb946b3b 334 SUPERFAMILY SSF47648 1 67 8.24E-18 T 21-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 Gene3D G3DSA:3.40.50.150 149 219 6.5E-30 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 Gene3D G3DSA:3.40.50.150 256 378 6.5E-30 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 301 313 7.1E-5 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 198 212 7.1E-5 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PANTHER PTHR18895 258 381 4.6E-100 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PANTHER PTHR18895 42 223 4.6E-100 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 Pfam PF02926 THUMP domain 24 159 3.2E-7 T 21-04-2016 IPR004114 THUMP domain GO:0003723 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PANTHER PTHR18895:SF62 258 381 4.6E-100 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 PANTHER PTHR18895:SF62 42 223 4.6E-100 T 21-04-2016 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 SUPERFAMILY SSF53335 259 376 2.92E-35 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 SUPERFAMILY SSF53335 146 222 2.92E-35 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 SMART SM00981 58 159 9.0E-9 T 21-04-2016 IPR004114 THUMP domain GO:0003723 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 304 310 - T 21-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HSISS4_RS01135 a70d2b0bb675c95020695ed6c299b14a 388 Pfam PF01170 Putative RNA methylase family UPF0020 167 370 3.8E-56 T 21-04-2016 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 Gene3D G3DSA:3.40.190.10 34 138 4.0E-65 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 Gene3D G3DSA:3.40.190.10 276 319 4.0E-65 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PANTHER PTHR30222 11 354 6.4E-111 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 82 96 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 209 228 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 154 168 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 172 191 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 39 55 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 129 145 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 55 76 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 253 272 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 298 324 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 98 111 9.4E-63 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PANTHER PTHR30222:SF5 11 354 6.4E-111 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 Pfam PF13416 Bacterial extracellular solute-binding protein 49 319 6.1E-41 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 Gene3D G3DSA:3.40.190.10 140 275 4.5E-20 T 21-04-2016 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 PIRSF PIRSF019574 1 354 2.3E-130 T 21-04-2016 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 HSISS4_RS07335 43eefc13b3ef096de1adaf4dfe563975 355 SUPERFAMILY SSF53850 34 351 1.4E-94 T 21-04-2016 HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 PANTHER PTHR11751:SF303 9 399 9.6E-161 T 21-04-2016 HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 Gene3D G3DSA:3.90.1150.10 280 403 2.0E-37 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 PANTHER PTHR11751 9 399 9.6E-161 T 21-04-2016 HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 Pfam PF00155 Aminotransferase class I and II 34 383 5.7E-45 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 SUPERFAMILY SSF53383 6 399 8.61E-94 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07915 e60a988ee8279e0b5a5db45c14a06a30 404 Gene3D G3DSA:3.40.640.10 51 279 6.8E-67 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 Gene3D G3DSA:3.90.1150.10 250 348 6.4E-25 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 347 1.3E-90 T 21-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 SUPERFAMILY SSF53383 18 347 2.25E-71 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 Gene3D G3DSA:3.40.640.10 35 249 4.5E-59 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 PANTHER PTHR11751 7 349 7.2E-84 T 21-04-2016 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 Pfam PF00155 Aminotransferase class I and II 21 343 7.1E-54 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 PANTHER PTHR11751:SF398 7 349 7.2E-84 T 21-04-2016 HSISS4_RS03880 57ebb3d27f850b517f43abb057b0ff05 350 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 349 51.319 T 21-04-2016 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9|UniPathway: UPA00031 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 Gene3D G3DSA:3.40.50.720 30 98 1.8E-20 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 PANTHER PTHR10996 10 347 2.5E-105 T 21-04-2016 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 100 273 2.4E-41 T 21-04-2016 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 SUPERFAMILY SSF55021 307 389 1.57E-13 T 21-04-2016 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 SUPERFAMILY SSF51735 84 274 2.06E-41 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 21-04-2016 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 PANTHER PTHR10996:SF20 10 347 2.5E-105 T 21-04-2016 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 SUPERFAMILY SSF52283 28 109 3.78E-20 T 21-04-2016 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 Gene3D G3DSA:3.40.50.720 99 276 1.5E-46 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 30 305 4.8E-18 T 21-04-2016 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 HSISS4_RS07305 0e96dc2da392418f63627904131878ac 392 Gene3D G3DSA:3.30.70.260 302 389 5.4E-22 T 21-04-2016 HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 279 8.5E-84 T 21-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 Gene3D G3DSA:3.40.50.720 2 229 3.7E-62 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 Pfam PF04321 RmlD substrate binding domain 2 280 4.0E-108 T 21-04-2016 IPR029903 RmlD-like substrate binding domain HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 PANTHER PTHR10491:SF4 1 283 3.5E-99 T 21-04-2016 HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 PANTHER PTHR10491 1 283 3.5E-99 T 21-04-2016 IPR005913 dTDP-4-dehydrorhamnose reductase family HSISS4_RS07120 9ee8f77f150dc80c83a7362c25223b16 283 SUPERFAMILY SSF51735 2 280 5.55E-86 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 Pfam PF00107 Zinc-binding dehydrogenase 179 271 6.9E-21 T 21-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 PANTHER PTHR11695:SF601 12 345 4.2E-134 T 21-04-2016 HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 SUPERFAMILY SSF51735 147 279 1.17E-32 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 Gene3D G3DSA:3.40.50.720 171 287 5.7E-32 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 Gene3D G3DSA:3.90.180.10 1 170 5.7E-41 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 SUPERFAMILY SSF50129 1 180 1.33E-43 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 PANTHER PTHR11695 12 345 4.2E-134 T 21-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 21-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 HSISS4_RS05150 ffda98100922c686c9e303f0f9480c09 345 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 123 5.6E-22 T 21-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HSISS4_RS03160 3fd050c31bb106edd1663deae211fda9 211 PANTHER PTHR12598:SF0 1 207 1.3E-68 T 21-04-2016 HSISS4_RS03160 3fd050c31bb106edd1663deae211fda9 211 Gene3D G3DSA:3.20.20.380 2 208 2.7E-69 T 21-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 HSISS4_RS03160 3fd050c31bb106edd1663deae211fda9 211 PANTHER PTHR12598 1 207 1.3E-68 T 21-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 HSISS4_RS03160 3fd050c31bb106edd1663deae211fda9 211 Pfam PF03932 CutC family 3 208 9.3E-65 T 21-04-2016 IPR005627 Copper homeostasis protein CutC GO:0005507|GO:0055070 HSISS4_RS03160 3fd050c31bb106edd1663deae211fda9 211 SUPERFAMILY SSF110395 3 210 1.15E-55 T 21-04-2016 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 245 257 - T 21-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Pfam PF02151 UvrB/uvrC motif 364 398 1.7E-7 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 SMART SM01086 648 736 1.6E-28 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Gene3D G3DSA:4.10.860.10 368 401 4.6E-5 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 154 274 5.8E-14 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PANTHER PTHR11638 101 756 0.0 T 21-04-2016 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 SUPERFAMILY SSF52540 111 363 4.86E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 589 603 3.1E-37 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 556 574 3.1E-37 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 482 500 3.1E-37 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 527 545 3.1E-37 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Gene3D G3DSA:3.40.50.300 112 292 1.0E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 SMART SM00382 478 649 7.8E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 SMART SM00382 149 289 6.0E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Gene3D G3DSA:3.40.50.300 433 658 1.0E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Pfam PF07724 AAA domain (Cdc48 subfamily) 477 640 2.4E-48 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 SUPERFAMILY SSF52540 427 721 4.36E-75 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 648 721 4.8E-23 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Gene3D G3DSA:1.10.8.60 293 367 3.0E-31 T 21-04-2016 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 Gene3D G3DSA:1.10.8.60 659 747 1.0E-27 T 21-04-2016 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 512 530 - T 21-04-2016 IPR028299 ClpA/B, conserved site 2 HSISS4_RS02840 ca5224c65f12fd4db653ce64328d4256 756 PANTHER PTHR11638:SF117 101 756 0.0 T 21-04-2016 HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 103 311 2.4E-42 T 21-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 Gene3D G3DSA:2.60.120.10 226 312 1.7E-29 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 PANTHER PTHR18964 1 254 1.1E-98 T 21-04-2016 HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 Gene3D G3DSA:2.60.120.10 1 215 6.8E-77 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 SUPERFAMILY SSF51182 1 311 3.86E-102 T 21-04-2016 IPR011051 RmlC-like cupin domain HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 PIRSF PIRSF036894 1 313 2.8E-126 T 21-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 PANTHER PTHR18964:SF114 1 254 1.1E-98 T 21-04-2016 HSISS4_RS08345 f1d67dd892e92386b0c18bc6673202dc 315 Pfam PF01238 Phosphomannose isomerase type I 4 311 9.2E-52 T 21-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 201 2.3E-21 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 Gene3D G3DSA:3.40.50.1000 95 230 9.1E-41 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 7.3E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 7.3E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 7.3E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 7.3E-5 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 TIGRFAM TIGR02254 YjjG/YfnB: noncanonical pyrimidine nucleotidase, YjjG family 3 229 4.7E-59 T 21-04-2016 IPR011951 HAD-superfamily hydrolase, subfamily IA, YjjG/YfnB GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 SUPERFAMILY SSF56784 3 229 1.76E-47 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PANTHER PTHR12725:SF57 1 231 1.9E-37 T 21-04-2016 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 113 196 5.6E-12 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 PANTHER PTHR12725 1 231 1.9E-37 T 21-04-2016 HSISS4_RS05990 6a13b087d9f51b863cf77d3881b48e8c 231 Gene3D G3DSA:1.10.150.240 16 94 4.0E-25 T 21-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 PIRSF PIRSF002122 2 156 1.6E-55 T 21-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.21 T 21-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 21-04-2016 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.3E-64 T 21-04-2016 IPR023798 Ribosomal protein S7 domain HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 SUPERFAMILY SSF47973 1 149 4.32E-59 T 21-04-2016 IPR023798 Ribosomal protein S7 domain HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 PANTHER PTHR11205 1 156 1.6E-86 T 21-04-2016 IPR000235 Ribosomal protein S5/S7 GO:0006412 HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 Gene3D G3DSA:1.10.455.10 7 156 4.1E-65 T 21-04-2016 IPR023798 Ribosomal protein S7 domain HSISS4_RS08590 a5e5ac3e54e2564450ed0dc5a7e8aa6f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 2.2E-68 T 21-04-2016 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS06075 ec4ae4cd67682f3dc60e8a3577a232b7 364 SUPERFAMILY SSF55874 278 358 3.27E-9 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06075 ec4ae4cd67682f3dc60e8a3577a232b7 364 PANTHER PTHR24421:SF10 12 358 4.8E-59 T 21-04-2016 HSISS4_RS06075 ec4ae4cd67682f3dc60e8a3577a232b7 364 PANTHER PTHR24421 12 358 4.8E-59 T 21-04-2016 HSISS4_RS06075 ec4ae4cd67682f3dc60e8a3577a232b7 364 Gene3D G3DSA:3.30.565.10 256 327 4.5E-5 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06075 ec4ae4cd67682f3dc60e8a3577a232b7 364 Pfam PF07730 Histidine kinase 175 239 2.6E-17 T 21-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 SUPERFAMILY SSF53633 1 288 4.58E-69 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 PIRSF PIRSF000726 1 452 7.2E-83 T 21-04-2016 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 21-04-2016 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 SUPERFAMILY SSF55021 298 359 9.16E-9 T 21-04-2016 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 PANTHER PTHR21499 3 450 1.2E-136 T 21-04-2016 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 6.1E-85 T 21-04-2016 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 Pfam PF00696 Amino acid kinase family 2 276 3.1E-45 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 Gene3D G3DSA:3.40.1160.10 105 288 5.0E-51 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 Gene3D G3DSA:3.40.1160.10 1 54 5.0E-51 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 SUPERFAMILY SSF55021 372 450 6.01E-22 T 21-04-2016 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 PANTHER PTHR21499:SF3 3 450 1.2E-136 T 21-04-2016 HSISS4_RS01770 3b9fb91b2975174676d049a51e52e119 452 Pfam PF13840 ACT domain 380 444 1.4E-10 T 21-04-2016 IPR027795 GATS-like ACT domain HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 SUPERFAMILY SSF53271 3 178 7.34E-60 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 PANTHER PTHR22573:SF56 4 180 5.7E-81 T 21-04-2016 HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 174 6.0E-64 T 21-04-2016 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620|UniPathway: UPA00591 HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 PANTHER PTHR22573 4 180 5.7E-81 T 21-04-2016 HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 Gene3D G3DSA:3.40.50.2020 2 179 1.3E-81 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00060 cf78329246fc1e7234a9332ecb2a82b3 180 Pfam PF00156 Phosphoribosyl transferase domain 10 160 3.7E-25 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Gene3D G3DSA:4.10.950.10 196 274 5.5E-34 T 21-04-2016 IPR014726 Ribosomal protein L2, domain 3 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 6.9E-35 T 21-04-2016 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Gene3D G3DSA:2.40.50.140 2 114 2.5E-52 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 275 7.6E-136 T 21-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.019 T 21-04-2016 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Gene3D G3DSA:2.30.30.30 118 195 1.5E-34 T 21-04-2016 IPR014722 Ribosomal protein L2 domain 2 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 1.2E-55 T 21-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 SUPERFAMILY SSF50249 3 125 5.48E-52 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 PIRSF PIRSF002158 5 276 1.7E-98 T 21-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 SUPERFAMILY SSF50104 126 273 7.22E-58 T 21-04-2016 IPR008991 Translation protein SH3-like domain HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 SMART SM01383 42 118 1.9E-46 T 21-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 PANTHER PTHR13691 3 276 9.5E-147 T 21-04-2016 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 SMART SM01382 124 253 1.1E-87 T 21-04-2016 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09335 eb9bc27c2eed3e20a8f78ccd289ca4ef 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 21-04-2016 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 SMART SM00646 571 699 4.4E-40 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 Pfam PF08481 GBS Bsp-like repeat 298 386 6.6E-28 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 Pfam PF08481 GBS Bsp-like repeat 399 489 2.5E-30 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 SUPERFAMILY SSF53187 511 703 4.71E-54 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 513 699 8.2E-55 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 135 267 2.3E-21 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 SMART SM00047 111 271 3.7E-44 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 PANTHER PTHR30404:SF0 509 703 1.4E-51 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 Gene3D G3DSA:3.40.630.40 511 703 1.8E-62 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 PRINTS PR01002 Flagellar protein FlgJ signature 180 201 4.9E-9 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 PRINTS PR01002 Flagellar protein FlgJ signature 248 266 4.9E-9 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 PRINTS PR01002 Flagellar protein FlgJ signature 158 179 4.9E-9 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 PANTHER PTHR30404 509 703 1.4E-51 T 21-04-2016 HSISS4_RS04475 3d3fa354ce1218c7fc1130d86130939f 708 TIGRFAM TIGR03726 strep_RK_lipo: putative cross-wall-targeting lipoprotein signal 7 38 1.5E-5 T 21-04-2016 IPR021197 Cross-wall-targeting lipoprotein motif HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Pfam PF05190 MutS family domain IV 415 505 1.7E-28 T 21-04-2016 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 PANTHER PTHR11361:SF86 1 852 0.0 T 21-04-2016 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SMART SM00534 595 782 3.9E-113 T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 676 692 - T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Pfam PF05188 MutS domain II 126 239 1.2E-15 T 21-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Gene3D G3DSA:3.40.50.300 554 785 2.6E-81 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 6 844 23.928 T 21-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SUPERFAMILY SSF52540 554 786 4.8E-61 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 7 850 0.0 T 21-04-2016 IPR005748 DNA mismatch repair protein MutS, type 1 GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 PANTHER PTHR11361 1 852 0.0 T 21-04-2016 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SMART SM00533 270 578 5.6E-113 T 21-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SUPERFAMILY SSF48334 254 552 9.68E-90 T 21-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SUPERFAMILY SSF55271 4 114 4.58E-42 T 21-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Gene3D G3DSA:1.10.1420.10 249 455 1.1E-54 T 21-04-2016 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Pfam PF00488 MutS domain V 598 785 1.5E-80 T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Pfam PF01624 MutS domain I 8 118 5.9E-44 T 21-04-2016 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 SUPERFAMILY SSF53150 118 265 1.7E-32 T 21-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Gene3D G3DSA:3.30.420.110 125 246 9.3E-31 T 21-04-2016 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Pfam PF05192 MutS domain III 256 546 5.3E-44 T 21-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00300 ff67a6434e8a79d0220b01886bbf9947 852 Gene3D G3DSA:3.40.1170.10 3 118 1.8E-49 T 21-04-2016 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 418 2.1E-147 T 21-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 PANTHER PTHR10520 1 420 1.2E-225 T 21-04-2016 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Gene3D G3DSA:3.30.1490.20 120 189 1.0E-31 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 2.9E-31 T 21-04-2016 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 416 1.6E-18 T 21-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 294 5.3E-81 T 21-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Gene3D G3DSA:3.90.600.10 328 418 6.3E-20 T 21-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 SUPERFAMILY SSF51246 326 418 5.89E-20 T 21-04-2016 IPR011054 Rudiment single hybrid motif HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 SUPERFAMILY SSF56059 103 322 4.95E-65 T 21-04-2016 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Gene3D G3DSA:3.40.50.20 2 94 1.0E-32 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 SUPERFAMILY SSF52440 1 101 2.16E-30 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 288 295 - T 21-04-2016 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Gene3D G3DSA:3.30.470.20 190 322 1.2E-57 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 SMART SM01210 327 419 1.5E-26 T 21-04-2016 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 SMART SM01209 102 294 1.3E-132 T 21-04-2016 HSISS4_RS00255 4622beb79fe71b0613f306e255f7f98c 420 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 419 41.778 T 21-04-2016 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.20.120.10 672 702 3.0E-9 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 1.8E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 240 299 3.1E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 875 935 1.2E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 766 824 5.4E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 691 748 7.2E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 390 453 3.4E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 177 238 2.3E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 482 545 4.4E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 171 275 5.23E-27 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 305 464 5.23E-27 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 616 819 5.71E-29 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 824 840 1.96E-16 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 869 946 1.96E-16 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 703 731 2.5E-11 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 294 340 1.1E-5 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Pfam PF01473 Putative cell wall binding repeat 234 247 0.25 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Pfam PF01473 Putative cell wall binding repeat 685 699 0.31 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Pfam PF01473 Putative cell wall binding repeat 611 627 0.13 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 168 233 1.3E-11 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 757 837 1.5E-8 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 366 479 5.4E-17 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 234 293 1.5E-11 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 599 671 1.5E-11 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 SUPERFAMILY SSF69360 536 584 5.71E-29 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 551 598 1.5E-4 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 875 946 9.4E-15 T 21-04-2016 HSISS4_RS06550 10343c975ffc858748858089eb52d99b 951 Gene3D G3DSA:2.10.270.10 480 550 2.5E-11 T 21-04-2016 HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 Pfam PF00437 Type II/IV secretion system protein 9 261 4.0E-42 T 21-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 SUPERFAMILY SSF52540 3 268 9.81E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 Gene3D G3DSA:3.40.50.300 130 269 3.1E-50 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 21-04-2016 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 Gene3D G3DSA:3.30.450.90 2 109 2.4E-15 T 21-04-2016 HSISS4_RS09075 76d2ea4b313c661e9c86bff0c69c5dff 313 PANTHER PTHR30258 9 267 2.6E-65 T 21-04-2016 HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 PIRSF PIRSF006113 20 143 7.9E-27 T 21-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 Gene3D G3DSA:3.30.479.10 22 144 6.9E-42 T 21-04-2016 HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 25 143 1.6E-36 T 21-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 SUPERFAMILY SSF55620 22 143 4.67E-40 T 21-04-2016 HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 PANTHER PTHR12589:SF5 14 147 1.9E-43 T 21-04-2016 HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 25 113 6.9E-30 T 21-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HSISS4_RS05565 2afdfc8767934b9875c0c5f45b677283 147 PANTHER PTHR12589 14 147 1.9E-43 T 21-04-2016 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein HSISS4_RS03765 b93dda4f258d93ae2d90da3a620e10ca 262 Gene3D G3DSA:3.40.50.880 45 223 9.5E-17 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS03765 b93dda4f258d93ae2d90da3a620e10ca 262 PANTHER PTHR21343 8 261 6.9E-102 T 21-04-2016 HSISS4_RS03765 b93dda4f258d93ae2d90da3a620e10ca 262 PANTHER PTHR21343:SF9 8 261 6.9E-102 T 21-04-2016 HSISS4_RS03765 b93dda4f258d93ae2d90da3a620e10ca 262 SUPERFAMILY SSF52317 33 207 4.88E-27 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS03765 b93dda4f258d93ae2d90da3a620e10ca 262 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 19 214 2.5E-44 T 21-04-2016 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 UniPathway: UPA00148 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 Gene3D G3DSA:1.10.1660.10 57 109 1.5E-5 T 21-04-2016 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 Gene3D G3DSA:1.10.1660.10 3 56 3.0E-24 T 21-04-2016 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 SUPERFAMILY SSF46955 3 104 1.87E-28 T 21-04-2016 IPR009061 Putative DNA-binding domain HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 Pfam PF13411 MerR HTH family regulatory protein 3 68 1.4E-15 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 Gene3D G3DSA:1.10.490.50 150 236 6.6E-26 T 21-04-2016 IPR012925 TipAS antibiotic-recognition domain HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 Pfam PF07739 TipAS antibiotic-recognition domain 124 234 1.4E-25 T 21-04-2016 IPR012925 TipAS antibiotic-recognition domain HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 PANTHER PTHR30204:SF27 3 236 1.7E-40 T 21-04-2016 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 PANTHER PTHR30204 3 236 1.7E-40 T 21-04-2016 HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 SUPERFAMILY SSF89082 148 236 7.72E-25 T 21-04-2016 IPR012925 TipAS antibiotic-recognition domain HSISS4_RS01075 5f81b56da342950ec86d6e9f81a45e8f 236 SMART SM00422 3 71 1.5E-22 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PANTHER PTHR30050:SF2 8 454 2.1E-172 T 21-04-2016 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 364 432 2.3E-31 T 21-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Gene3D G3DSA:1.10.8.60 283 350 2.1E-19 T 21-04-2016 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 SMART SM00760 363 432 5.7E-41 T 21-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 9 453 1.9E-154 T 21-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Gene3D G3DSA:1.10.1750.10 360 454 3.3E-39 T 21-04-2016 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PANTHER PTHR30050 8 454 2.1E-172 T 21-04-2016 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Gene3D G3DSA:3.40.50.300 100 281 2.9E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 212 226 5.6E-49 T 21-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 413 432 5.6E-49 T 21-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 148 168 5.6E-49 T 21-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 180 194 5.6E-49 T 21-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 248 275 5.6E-49 T 21-04-2016 IPR020591 Chromosomal replication control, initiator DnaA-like HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 ProSitePatterns PS01008 DnaA protein signature. 413 432 - T 21-04-2016 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 SUPERFAMILY SSF48295 361 454 7.06E-35 T 21-04-2016 IPR010921 Trp repressor/replication initiator GO:0043565 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 SUPERFAMILY SSF52540 114 328 2.66E-43 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 6 454 30.517 T 21-04-2016 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 SMART SM00382 147 280 3.5E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00005 8e2404e8db90ccb387582d4f9614a29b 454 Pfam PF00308 Bacterial dnaA protein 115 332 2.6E-85 T 21-04-2016 IPR013317 Chromosomal replication initiator protein DnaA HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 SMART SM00331 2 240 7.9E-30 T 21-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 Pfam PF13672 Protein phosphatase 2C 12 201 7.5E-15 T 21-04-2016 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 SUPERFAMILY SSF81606 2 241 1.22E-58 T 21-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 SMART SM00332 1 238 2.1E-11 T 21-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 Gene3D G3DSA:3.60.40.10 2 240 1.9E-63 T 21-04-2016 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04660+3.1.3.16 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 PANTHER PTHR13832 1 244 2.1E-61 T 21-04-2016 IPR015655 Protein phosphatase 2C family GO:0004722|GO:0006470 KEGG: 04660+3.1.3.16 HSISS4_RS06920 296d62d0f36ef9e0e9d4bb3977bb5d4e 245 PANTHER PTHR13832:SF278 1 244 2.1E-61 T 21-04-2016 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 Gene3D G3DSA:1.10.10.10 124 224 2.2E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 2.1E-25 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 SMART SM00862 147 222 2.4E-21 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 Gene3D G3DSA:3.40.50.2300 2 122 4.4E-35 T 21-04-2016 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 PANTHER PTHR26402 2 223 1.4E-125 T 21-04-2016 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 SUPERFAMILY SSF52172 1 182 2.49E-37 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 PANTHER PTHR26402:SF519 2 223 1.4E-125 T 21-04-2016 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 SMART SM00448 2 112 3.0E-35 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06150 0f6776c959561134294afb5135e4fb51 226 Pfam PF00072 Response regulator receiver domain 4 113 5.3E-25 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05345 40f2cc8ecc7873b99977e0884b2bef2a 381 PANTHER PTHR30519:SF3 9 377 5.2E-56 T 21-04-2016 HSISS4_RS05345 40f2cc8ecc7873b99977e0884b2bef2a 381 PANTHER PTHR30519 9 377 5.2E-56 T 21-04-2016 HSISS4_RS05345 40f2cc8ecc7873b99977e0884b2bef2a 381 Gene3D G3DSA:3.20.20.210 6 379 2.2E-82 T 21-04-2016 HSISS4_RS05345 40f2cc8ecc7873b99977e0884b2bef2a 381 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 189 353 2.4E-4 T 21-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05345 40f2cc8ecc7873b99977e0884b2bef2a 381 SUPERFAMILY SSF51726 8 378 6.93E-57 T 21-04-2016 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Gene3D G3DSA:1.10.340.30 34 135 9.4E-46 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 48 167 3.8E-19 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 SUPERFAMILY SSF48150 17 235 1.4E-73 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Pfam PF00633 Helix-hairpin-helix motif 113 140 5.4E-8 T 21-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 PANTHER PTHR10359 12 335 2.1E-101 T 21-04-2016 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 SUPERFAMILY SSF55811 233 377 1.22E-18 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Gene3D G3DSA:3.90.79.10 243 381 5.7E-29 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 20 285 3.1E-97 T 21-04-2016 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Gene3D G3DSA:1.10.1670.10 136 236 1.6E-34 T 21-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 SMART SM00478 52 203 9.4E-47 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS08465 e54a9915fcd5806a28956fd06f7221aa 383 Pfam PF14815 NUDIX domain 248 375 8.7E-16 T 21-04-2016 IPR029119 MutY, C-terminal HSISS4_RS08175 2291e3c0b4182aae647b6206b42ebf5e 132 PANTHER PTHR34980 1 117 1.9E-12 T 21-04-2016 HSISS4_RS08175 2291e3c0b4182aae647b6206b42ebf5e 132 Pfam PF05656 Protein of unknown function (DUF805) 12 119 6.7E-18 T 21-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 5.5E-21 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 Gene3D G3DSA:1.10.260.40 4 54 3.1E-24 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 Gene3D G3DSA:3.40.50.2300 170 303 1.9E-30 T 21-04-2016 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 PANTHER PTHR30146:SF31 2 316 1.3E-98 T 21-04-2016 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 Pfam PF13377 Periplasmic binding protein-like domain 166 320 5.7E-26 T 21-04-2016 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 Gene3D G3DSA:3.40.50.2300 55 169 8.2E-43 T 21-04-2016 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 5.6E-5 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 5.6E-5 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 SUPERFAMILY SSF53822 61 315 3.34E-65 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 PANTHER PTHR30146 2 316 1.3E-98 T 21-04-2016 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 SMART SM00354 2 72 1.1E-37 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS08365 5e855e897870b9b0526be75f1b95d582 321 SUPERFAMILY SSF47413 3 57 1.13E-16 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 SUPERFAMILY SSF74731 3 116 3.79E-49 T 21-04-2016 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 70 1.0E-13 T 21-04-2016 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.7E-41 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.7E-41 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.7E-41 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 PANTHER PTHR10986 2 117 3.6E-64 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 Gene3D G3DSA:1.10.1900.20 55 117 1.4E-31 T 21-04-2016 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 30.365 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 3.9E-50 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 PANTHER PTHR10986:SF12 2 117 3.6E-64 T 21-04-2016 HSISS4_RS04510 108d196cf32aa09fe3c81692f5576cf4 119 Pfam PF00453 Ribosomal protein L20 3 109 6.4E-49 T 21-04-2016 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 471 34.297 T 21-04-2016 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Gene3D G3DSA:3.40.50.300 98 298 5.3E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 SMART SM00963 2 87 4.1E-29 T 21-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Pfam PF02978 Signal peptide binding domain 328 427 1.2E-31 T 21-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 SUPERFAMILY SSF52540 43 355 1.86E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 SMART SM00382 100 408 1.3E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 SMART SM00962 101 297 6.2E-114 T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Gene3D G3DSA:1.20.120.140 3 90 3.5E-32 T 21-04-2016 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 9.5E-21 T 21-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 PANTHER PTHR11564:SF7 1 435 3.5E-254 T 21-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 6.1E-77 T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 428 6.7E-189 T 21-04-2016 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 SUPERFAMILY SSF47446 328 429 4.25E-35 T 21-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 Gene3D G3DSA:1.10.260.30 328 430 5.1E-38 T 21-04-2016 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 HSISS4_RS05420 cf71f7dd3c558c19c48f8a7f2080b561 520 PANTHER PTHR11564 1 435 3.5E-254 T 21-04-2016 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 Pfam PF08544 GHMP kinases C terminal 206 283 6.1E-15 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 SUPERFAMILY SSF55060 159 290 4.68E-32 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 Pfam PF00288 GHMP kinases N terminal domain 78 140 3.5E-12 T 21-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 SUPERFAMILY SSF54211 8 175 9.11E-34 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 PANTHER PTHR10457 10 283 1.5E-48 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 Gene3D G3DSA:3.30.70.890 167 288 3.3E-35 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 265 8.5E-71 T 21-04-2016 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|UniPathway: UPA00057 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 Gene3D G3DSA:3.30.230.10 69 166 2.5E-25 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 Gene3D G3DSA:3.30.230.10 4 47 6.3E-12 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 PRINTS PR00959 Mevalonate kinase family signature 81 103 8.6E-20 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 PRINTS PR00959 Mevalonate kinase family signature 250 267 8.6E-20 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS02585 fcf0231c66f469359939abef01c596a0 292 PRINTS PR00959 Mevalonate kinase family signature 10 34 8.6E-20 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF69360 1282 1489 7.22E-34 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF51445 818 979 7.98E-26 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 8.0E-8 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.20.120.10 1056 1097 9.7E-9 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF69360 1150 1290 1.18E-25 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 160 198 1.4E-5 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 1098 1138 8.1E-10 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF69360 162 198 6.28E-6 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:3.20.20.80 831 957 9.9E-20 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF69360 1055 1145 1.06E-19 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1352 1415 4.7E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1158 1219 8.0E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1417 1479 1.5E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1086 1142 6.3E-13 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1246 1307 4.7E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 1330 1417 6.5E-17 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Pfam PF02324 Glycosyl hydrolase family 70 267 1063 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:3.20.20.80 363 568 8.0E-25 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:3.20.20.80 602 657 8.0E-25 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF51445 604 651 8.16E-33 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 SUPERFAMILY SSF51445 365 567 8.16E-33 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 1244 1329 5.6E-19 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 1159 1239 4.4E-13 T 21-04-2016 HSISS4_RS03955 3ed4a4dcc1003e8b8a5aac7841903303 1493 Gene3D G3DSA:2.10.270.10 1418 1489 2.3E-11 T 21-04-2016 HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 SUPERFAMILY SSF53448 1 286 4.96E-95 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 3.6E-155 T 21-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 Gene3D G3DSA:3.90.550.10 1 266 9.1E-71 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 PANTHER PTHR22572 2 269 8.9E-184 T 21-04-2016 HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 PANTHER PTHR22572:SF105 2 269 8.9E-184 T 21-04-2016 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HSISS4_RS03820 2c0d02ccfd56200cb407fef59f9b8543 289 Pfam PF00483 Nucleotidyl transferase 2 237 3.6E-74 T 21-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HSISS4_RS04640 f8a5d681219a0174e89bf4969b48b8c2 471 Pfam PF01943 Polysaccharide biosynthesis protein 3 264 2.0E-23 T 21-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HSISS4_RS04640 f8a5d681219a0174e89bf4969b48b8c2 471 PANTHER PTHR30250 2 456 4.6E-46 T 21-04-2016 HSISS4_RS04640 f8a5d681219a0174e89bf4969b48b8c2 471 PANTHER PTHR30250:SF0 2 456 4.6E-46 T 21-04-2016 HSISS4_RS04640 f8a5d681219a0174e89bf4969b48b8c2 471 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 320 458 4.2E-22 T 21-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 PANTHER PTHR11730:SF17 1 403 3.2E-162 T 21-04-2016 HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 Pfam PF00909 Ammonium Transporter Family 7 403 4.3E-115 T 21-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 PANTHER PTHR11730 1 403 3.2E-162 T 21-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 Gene3D G3DSA:1.10.3430.10 2 384 6.7E-128 T 21-04-2016 IPR029020 Ammonium/urea transporter HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 TIGRFAM TIGR00836 amt: ammonium transporter 7 403 7.0E-129 T 21-04-2016 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 SUPERFAMILY SSF111352 2 384 3.27E-118 T 21-04-2016 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 HSISS4_RS02330 e8a2140beee36c9d623726b7edf9f00e 411 ProSitePatterns PS01219 Ammonium transporters signature. 157 182 - T 21-04-2016 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 Gene3D G3DSA:3.40.50.1370 149 282 1.2E-44 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 11 304 8.6E-89 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.7E-19 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 2.7E-19 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 2.7E-19 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 139 150 2.7E-19 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 138 155 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 81 90 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 43 65 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 9.4E-30 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 Gene3D G3DSA:3.40.50.1370 11 148 2.4E-43 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 159 302 1.6E-20 T 21-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 SUPERFAMILY SSF53671 9 306 1.81E-86 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PANTHER PTHR11405 11 308 3.9E-119 T 21-04-2016 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 PANTHER PTHR11405:SF16 11 308 3.9E-119 T 21-04-2016 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 10 306 38.441 T 21-04-2016 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS02460 2e3e836e1e55dec582d8cce5f58910a7 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 11 152 1.0E-31 T 21-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 SUPERFAMILY SSF53335 15 287 2.43E-77 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 18 286 57.344 T 21-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 Gene3D G3DSA:3.40.50.150 3 211 7.9E-76 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 18 284 1.3E-84 T 21-04-2016 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 Gene3D G3DSA:1.10.8.100 214 287 3.5E-23 T 21-04-2016 IPR023165 rRNA adenine dimethylase-like HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 SMART SM00650 34 210 4.3E-88 T 21-04-2016 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 50 77 - T 21-04-2016 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 Pfam PF00398 Ribosomal RNA adenine dimethylase 18 255 4.7E-68 T 21-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HSISS4_RS08635 170cb4f3667c76d7b2c0ca1a5790d058 290 PANTHER PTHR11727 1 289 1.3E-94 T 21-04-2016 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 SUPERFAMILY SSF54593 2 126 9.26E-33 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 Gene3D G3DSA:3.10.180.10 3 124 2.4E-36 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 PANTHER PTHR10374:SF8 3 123 2.7E-43 T 21-04-2016 HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 PANTHER PTHR10374 3 123 2.7E-43 T 21-04-2016 HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 ProSitePatterns PS00934 Glyoxalase I signature 1. 6 27 - T 21-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 3 126 2.3E-38 T 21-04-2016 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 HSISS4_RS07325 2f25638a5c8cfc6a7e648072f6302963 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 122 3.8E-17 T 21-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 255 271 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 171 193 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 135 164 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 393 409 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 286 302 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 230 248 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PRINTS PR00072 Malic enzyme signature 73 97 1.2E-62 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PIRSF PIRSF000106 1 541 1.1E-204 T 21-04-2016 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471|GO:0006108|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 Pfam PF03949 Malic enzyme, NAD binding domain 259 514 1.4E-96 T 21-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 Gene3D G3DSA:3.40.50.720 257 541 1.8E-100 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PANTHER PTHR23406:SF34 6 541 4.0E-228 T 21-04-2016 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 PANTHER PTHR23406 6 541 4.0E-228 T 21-04-2016 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 SUPERFAMILY SSF51735 259 540 1.93E-85 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 SMART SM00919 259 515 5.7E-109 T 21-04-2016 IPR012302 Malic enzyme, NAD-binding GO:0004471|GO:0051287|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 ProSitePatterns PS00331 Malic enzymes signature. 255 271 - T 21-04-2016 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 Gene3D G3DSA:3.40.50.10380 3 256 3.8E-95 T 21-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 SUPERFAMILY SSF53223 3 258 6.19E-94 T 21-04-2016 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 SMART SM01274 67 249 1.7E-82 T 21-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HSISS4_RS06625 193b85da4f4eaa607b590dc70b509b3c 541 Pfam PF00390 Malic enzyme, N-terminal domain 68 249 1.5E-64 T 21-04-2016 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 Gene3D G3DSA:3.40.50.920 198 327 6.3E-46 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 Gene3D G3DSA:3.40.50.970 4 197 3.2E-79 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 PANTHER PTHR11624 1 330 1.8E-164 T 21-04-2016 IPR033247 Transketolase family HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 Pfam PF02780 Transketolase, C-terminal domain 197 320 2.5E-41 T 21-04-2016 IPR033248 Transketolase, C-terminal domain HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 SMART SM00861 7 182 2.6E-62 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 SUPERFAMILY SSF52922 193 327 1.96E-41 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 PANTHER PTHR11624:SF78 1 330 1.8E-164 T 21-04-2016 HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 SUPERFAMILY SSF52518 6 196 5.35E-64 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS04755 f817ec2c6d93bcc2718b4be2219ff616 332 Pfam PF02779 Transketolase, pyrimidine binding domain 7 181 2.9E-47 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS00855 5f3940b701b9c56b2a1869c530788378 385 PANTHER PTHR22926:SF3 4 373 1.6E-84 T 21-04-2016 HSISS4_RS00855 5f3940b701b9c56b2a1869c530788378 385 PANTHER PTHR22926 4 373 1.6E-84 T 21-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00855 5f3940b701b9c56b2a1869c530788378 385 ProSitePatterns PS01348 MraY family signature 2. 163 174 - T 21-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00855 5f3940b701b9c56b2a1869c530788378 385 Pfam PF00953 Glycosyl transferase family 4 88 245 2.0E-38 T 21-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 Pfam PF00005 ABC transporter 17 163 4.2E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 PANTHER PTHR24220 3 237 2.7E-133 T 21-04-2016 HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 SMART SM00382 26 224 9.0E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 PANTHER PTHR24220:SF434 3 237 2.7E-133 T 21-04-2016 HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 SUPERFAMILY SSF52540 1 239 1.93E-73 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05275 a2048c8c22970be26db3e0eb8be0512d 242 Gene3D G3DSA:3.40.50.300 1 234 2.9E-79 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02955 58fff0797e4319d1d46f41d3f4754cd0 122 SMART SM00316 2 73 5.9E-22 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02955 58fff0797e4319d1d46f41d3f4754cd0 122 PANTHER PTHR10724 1 85 4.0E-26 T 21-04-2016 HSISS4_RS02955 58fff0797e4319d1d46f41d3f4754cd0 122 Pfam PF00575 S1 RNA binding domain 2 73 1.9E-16 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02955 58fff0797e4319d1d46f41d3f4754cd0 122 SUPERFAMILY SSF50249 1 81 1.24E-19 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02955 58fff0797e4319d1d46f41d3f4754cd0 122 Gene3D G3DSA:2.40.50.140 2 80 4.7E-23 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 Gene3D G3DSA:3.40.50.2000 250 457 1.7E-73 T 21-04-2016 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 Pfam PF08323 Starch synthase catalytic domain 2 236 5.7E-82 T 21-04-2016 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 Pfam PF00534 Glycosyl transferases group 1 286 424 2.6E-13 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 SUPERFAMILY SSF53756 2 475 4.4E-124 T 21-04-2016 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 PANTHER PTHR12526 1 476 1.5E-150 T 21-04-2016 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 PANTHER PTHR12526:SF17 1 476 1.5E-150 T 21-04-2016 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 475 1.5E-176 T 21-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06840 3f9eac14da86cd2d42c4ce252484f8f4 476 Hamap MF_00484 Glycogen synthase [glgA]. 1 475 45.401 T 21-04-2016 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 SUPERFAMILY SSF47364 162 238 5.23E-18 T 21-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 PANTHER PTHR11564:SF16 161 461 8.7E-128 T 21-04-2016 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 Pfam PF02881 SRP54-type protein, helical bundle domain 177 241 1.0E-11 T 21-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 Gene3D G3DSA:1.20.120.140 189 274 3.0E-26 T 21-04-2016 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 Pfam PF00448 SRP54-type protein, GTPase domain 262 461 1.4E-75 T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 188 462 61.742 T 21-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 SMART SM00963 164 245 7.0E-20 T 21-04-2016 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 435 448 - T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 PANTHER PTHR11564 161 461 8.7E-128 T 21-04-2016 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 SMART SM00962 261 462 3.1E-111 T 21-04-2016 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: REACT_15380 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 SUPERFAMILY SSF52540 262 460 1.97E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 SMART SM00382 260 438 6.2E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 189 461 7.6E-108 T 21-04-2016 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 HSISS4_RS06950 1a29be75de23fdc0f075178fada34c4d 465 Gene3D G3DSA:3.40.50.300 275 461 2.8E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03815 ec9a07494c25a8341c7ad77775c7a7b9 448 SUPERFAMILY SSF53474 186 363 4.84E-21 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03815 ec9a07494c25a8341c7ad77775c7a7b9 448 Pfam PF10503 Esterase PHB depolymerase 195 313 5.7E-7 T 21-04-2016 IPR010126 Esterase, PHB depolymerase GO:0005576 HSISS4_RS03815 ec9a07494c25a8341c7ad77775c7a7b9 448 PANTHER PTHR10655:SF24 202 350 1.0E-15 T 21-04-2016 HSISS4_RS03815 ec9a07494c25a8341c7ad77775c7a7b9 448 PANTHER PTHR10655 202 350 1.0E-15 T 21-04-2016 HSISS4_RS03815 ec9a07494c25a8341c7ad77775c7a7b9 448 Gene3D G3DSA:3.40.50.1820 189 390 2.4E-22 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF01183 Glycosyl hydrolases family 25 164 349 3.7E-36 T 21-04-2016 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 SMART SM00641 161 273 0.0061 T 21-04-2016 IPR018077 Glycoside hydrolase, family 25 subgroup HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 600 687 2.0E-26 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 704 792 3.1E-26 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 498 585 1.1E-26 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 912 998 4.2E-19 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 389 479 5.2E-32 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Pfam PF08481 GBS Bsp-like repeat 807 897 3.0E-33 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 SUPERFAMILY SSF51445 160 367 1.19E-35 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS04770 8fffcd3f7a53ef2af2a1ec33ba947ff4 1183 Gene3D G3DSA:3.20.20.80 160 364 8.4E-48 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 Pfam PF07885 Ion channel 139 208 2.4E-18 T 21-04-2016 IPR013099 Potassium channel domain HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 PANTHER PTHR11537:SF169 44 217 7.8E-19 T 21-04-2016 HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 SUPERFAMILY SSF81324 13 210 6.8E-37 T 21-04-2016 HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 Gene3D G3DSA:1.20.120.350 13 120 5.7E-22 T 21-04-2016 IPR027359 Voltage-dependent channel, four helix bundle domain HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 Gene3D G3DSA:1.10.287.70 128 217 7.6E-24 T 21-04-2016 HSISS4_RS06910 2e44f97dae1d28d7430c873f0e4410f6 252 PANTHER PTHR11537 44 217 7.8E-19 T 21-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 PANTHER PTHR14503 2 44 6.0E-19 T 21-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-7 T 21-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 15.636 T 21-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 21-04-2016 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 Pfam PF00468 Ribosomal protein L34 2 44 1.4E-22 T 21-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08770 64aab8288b79288a0484b8a088016594 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 2 44 1.1E-20 T 21-04-2016 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 Gene3D G3DSA:3.90.20.20 29 116 1.6E-24 T 21-04-2016 IPR013805 GrpE nucleotide exchange factor, coiled-coil HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 ProSitePatterns PS01071 grpE protein signature. 128 172 - T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 SUPERFAMILY SSF58014 30 118 2.62E-22 T 21-04-2016 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 Pfam PF01025 GrpE 16 173 8.4E-46 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 PANTHER PTHR21237 12 172 2.9E-48 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 Gene3D G3DSA:2.30.22.10 118 173 1.3E-23 T 21-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 Hamap MF_01151 Protein GrpE [grpE]. 3 174 19.096 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 PRINTS PR00773 GrpE protein signature 75 90 2.8E-24 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 PRINTS PR00773 GrpE protein signature 125 140 2.8E-24 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 PRINTS PR00773 GrpE protein signature 47 63 2.8E-24 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 PRINTS PR00773 GrpE protein signature 153 172 2.8E-24 T 21-04-2016 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 HSISS4_RS00670 b034cf86c9b85bd1a7492cd028a15751 174 SUPERFAMILY SSF51064 126 173 4.32E-14 T 21-04-2016 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 Pfam PF00589 Phage integrase family 122 252 2.0E-7 T 21-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 Hamap MF_01817 Tyrosine recombinase XerD-like. 10 251 33.69 T 21-04-2016 IPR020876 Tyrosine recombinase XerD-like GO:0005737 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 Gene3D G3DSA:1.10.443.10 109 252 1.3E-15 T 21-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 SUPERFAMILY SSF56349 17 252 7.06E-21 T 21-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 PANTHER PTHR30349 2 253 2.2E-14 T 21-04-2016 HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 Gene3D G3DSA:1.10.150.130 15 87 7.9E-5 T 21-04-2016 IPR023109 Integrase/recombinase, N-terminal HSISS4_RS01240 1fa6d91d778e559549b6aea29d1cf63e 253 PANTHER PTHR30349:SF5 2 253 2.2E-14 T 21-04-2016 HSISS4_RS03795 b390f1956e81fa435d1753ef89221ac2 228 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 22 222 2.8E-76 T 21-04-2016 IPR006901 tRNA methyltransferase TrmK GO:0016429 HSISS4_RS03795 b390f1956e81fa435d1753ef89221ac2 228 SUPERFAMILY SSF53335 14 141 8.34E-11 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03795 b390f1956e81fa435d1753ef89221ac2 228 PANTHER PTHR38451 1 227 1.1E-80 T 21-04-2016 HSISS4_RS03795 b390f1956e81fa435d1753ef89221ac2 228 Gene3D G3DSA:3.40.50.150 5 154 9.7E-10 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03795 b390f1956e81fa435d1753ef89221ac2 228 PIRSF PIRSF018637 3 227 1.6E-73 T 21-04-2016 IPR006901 tRNA methyltransferase TrmK GO:0016429 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 Gene3D G3DSA:3.40.390.10 345 422 1.8E-5 T 21-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 Gene3D G3DSA:1.10.287.830 181 225 6.9E-17 T 21-04-2016 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 SUPERFAMILY SSF55486 56 596 1.56E-129 T 21-04-2016 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 Pfam PF08439 Oligopeptidase F 112 181 1.3E-20 T 21-04-2016 IPR013647 Oligopeptidase F, N-terminal domain HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 Pfam PF01432 Peptidase family M3 202 581 1.7E-83 T 21-04-2016 IPR001567 Peptidase M3A/M3B GO:0004222|GO:0006508 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 6 592 9.5E-179 T 21-04-2016 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 PANTHER PTHR11804 146 596 3.1E-112 T 21-04-2016 HSISS4_RS02090 69fdfec08d5a8c293a1908014455671d 601 PANTHER PTHR11804:SF8 146 596 3.1E-112 T 21-04-2016 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 PANTHER PTHR19211:SF54 240 487 7.8E-122 T 21-04-2016 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 PANTHER PTHR19211:SF54 4 210 7.8E-122 T 21-04-2016 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Gene3D G3DSA:3.40.50.300 3 74 1.1E-12 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Gene3D G3DSA:3.40.50.300 302 483 4.7E-30 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03090 f818689b365fd73427081982d1314354 487 PANTHER PTHR19211 240 487 7.8E-122 T 21-04-2016 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 PANTHER PTHR19211 4 210 7.8E-122 T 21-04-2016 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Gene3D G3DSA:3.40.50.300 95 223 1.0E-21 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03090 f818689b365fd73427081982d1314354 487 SUPERFAMILY SSF52540 3 189 1.15E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Pfam PF00005 ABC transporter 24 57 1.1E-6 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Pfam PF00005 ABC transporter 313 437 3.5E-17 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03090 f818689b365fd73427081982d1314354 487 SMART SM00382 29 173 1.8E-8 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03090 f818689b365fd73427081982d1314354 487 SMART SM00382 321 482 1.4E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03090 f818689b365fd73427081982d1314354 487 Pfam PF12848 ABC transporter 167 226 6.3E-7 T 21-04-2016 IPR032781 ABC-transporter extension domain HSISS4_RS03090 f818689b365fd73427081982d1314354 487 SUPERFAMILY SSF52540 302 483 2.85E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 PANTHER PTHR10366 2 337 4.1E-146 T 21-04-2016 HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 323 4.3E-59 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 3 334 1.1E-135 T 21-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 Gene3D G3DSA:3.90.25.10 180 231 3.2E-52 T 21-04-2016 HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 Gene3D G3DSA:3.90.25.10 263 337 3.2E-52 T 21-04-2016 HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 PANTHER PTHR10366:SF39 2 337 4.1E-146 T 21-04-2016 HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 SUPERFAMILY SSF51735 1 336 1.65E-95 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04310 d1297c9e23e4aa1606327a540cdeb671 337 Gene3D G3DSA:3.40.50.720 1 179 7.6E-52 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS00755 62edd248cad660c1b3a75b9d9be8a089 155 ProSitePatterns PS00893 Nudix box signature. 46 67 - T 21-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HSISS4_RS00755 62edd248cad660c1b3a75b9d9be8a089 155 SUPERFAMILY SSF55811 13 142 3.25E-23 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS00755 62edd248cad660c1b3a75b9d9be8a089 155 Gene3D G3DSA:3.90.79.10 13 150 1.3E-21 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS00755 62edd248cad660c1b3a75b9d9be8a089 155 Pfam PF00293 NUDIX domain 17 127 1.9E-14 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS00755 62edd248cad660c1b3a75b9d9be8a089 155 PANTHER PTHR22769 21 122 1.2E-12 T 21-04-2016 HSISS4_RS04170 baf892d778e21c6beda2a593e4740e1d 333 Gene3D G3DSA:3.40.50.2300 35 162 3.0E-57 T 21-04-2016 HSISS4_RS04170 baf892d778e21c6beda2a593e4740e1d 333 SUPERFAMILY SSF53822 36 259 4.4E-20 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS04170 baf892d778e21c6beda2a593e4740e1d 333 Gene3D G3DSA:3.40.50.2300 163 295 3.2E-55 T 21-04-2016 HSISS4_RS04170 baf892d778e21c6beda2a593e4740e1d 333 PANTHER PTHR35271 6 330 8.8E-63 T 21-04-2016 HSISS4_RS04170 baf892d778e21c6beda2a593e4740e1d 333 Pfam PF04392 ABC transporter substrate binding protein 38 326 3.0E-115 T 21-04-2016 IPR007487 ABC transporter, substrate-binding protein HSISS4_RS05140 74d53e9dba5bbf46aa279ba1965ec1ae 123 SUPERFAMILY SSF49503 18 122 2.47E-18 T 21-04-2016 IPR008972 Cupredoxin HSISS4_RS05140 74d53e9dba5bbf46aa279ba1965ec1ae 123 Gene3D G3DSA:2.60.40.420 22 122 1.8E-12 T 21-04-2016 IPR008972 Cupredoxin HSISS4_RS05140 74d53e9dba5bbf46aa279ba1965ec1ae 123 Pfam PF13473 Cupredoxin-like domain 14 122 5.1E-25 T 21-04-2016 IPR028096 EfeO-type cupredoxin-like domain HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 SMART SM00487 17 207 1.9E-40 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 SUPERFAMILY SSF52540 67 337 2.14E-55 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 Gene3D G3DSA:3.40.50.300 200 347 1.6E-37 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 PANTHER PTHR24031:SF334 6 343 2.1E-105 T 21-04-2016 HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 Pfam PF00271 Helicase conserved C-terminal domain 231 323 7.2E-20 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 SMART SM00490 242 323 6.8E-22 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 Gene3D G3DSA:3.40.50.300 4 199 5.1E-49 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 PANTHER PTHR24031 6 343 2.1E-105 T 21-04-2016 HSISS4_RS03735 672a47eabad581b7faa8447c83cb4634 360 Pfam PF00270 DEAD/DEAH box helicase 22 181 9.8E-39 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 21-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 Gene3D G3DSA:3.30.230.40 90 194 1.0E-31 T 21-04-2016 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 PANTHER PTHR23133:SF2 1 194 9.0E-103 T 21-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 SUPERFAMILY SSF54211 2 85 8.98E-33 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 174 1.4E-65 T 21-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 SUPERFAMILY SSF54211 87 179 4.05E-35 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 Gene3D G3DSA:3.30.230.40 1 89 1.0E-38 T 21-04-2016 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 PANTHER PTHR23133 1 194 9.0E-103 T 21-04-2016 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 41.676 T 21-04-2016 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HSISS4_RS03900 b626aa10f34d1a94d1048c8a8c8932f5 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 21-04-2016 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19|UniPathway: UPA00031 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 977 1009 4.7E-6 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 Pfam PF04650 YSIRK type signal peptide 6 28 4.5E-8 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 SUPERFAMILY SSF74914 720 835 3.01E-14 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 Pfam PF08363 Glucan-binding protein C 718 819 2.6E-11 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 Pfam PF08363 Glucan-binding protein C 408 647 1.1E-24 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 3 37 1.4E-9 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 Pfam PF00746 Gram positive anchor 975 1007 8.7E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 PRINTS PR01217 Proline rich extensin signature 930 955 3.6E-11 T 21-04-2016 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 PRINTS PR01217 Proline rich extensin signature 823 844 3.6E-11 T 21-04-2016 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 PRINTS PR01217 Proline rich extensin signature 858 874 3.6E-11 T 21-04-2016 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 PRINTS PR01217 Proline rich extensin signature 887 904 3.6E-11 T 21-04-2016 HSISS4_RS04545 a4621a4213498efc5ae292f9f67e672c 1011 SUPERFAMILY SSF74914 372 654 1.01E-27 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PANTHER PTHR24322:SF328 153 185 2.6E-59 T 21-04-2016 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PANTHER PTHR24322:SF328 10 137 2.6E-59 T 21-04-2016 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.97E-47 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 21-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 3.9E-67 T 21-04-2016 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PANTHER PTHR24322 153 185 2.6E-59 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PANTHER PTHR24322 10 137 2.6E-59 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 6.3E-9 T 21-04-2016 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 Gene3D G3DSA:3.40.50.720 2 243 1.7E-89 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 241 5.3E-98 T 21-04-2016 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321|UniPathway: UPA00094 HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.51E-17 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 6.51E-17 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.51E-17 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS01810 848310ec52930dde039eb38bba07fb06 244 SUPERFAMILY SSF51735 4 243 1.3E-84 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 Hamap MF_00105 Transcription elongation factor GreA [greA]. 4 157 30.84 T 21-04-2016 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 19 50 - T 21-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 PANTHER PTHR30437 1 157 3.1E-57 T 21-04-2016 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 Gene3D G3DSA:3.10.50.30 78 157 1.1E-27 T 21-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 PIRSF PIRSF006092 1 160 1.4E-46 T 21-04-2016 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 157 4.5E-26 T 21-04-2016 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 SUPERFAMILY SSF54534 83 157 1.05E-19 T 21-04-2016 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 Pfam PF03449 Transcription elongation factor, N-terminal 7 76 1.9E-25 T 21-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 SUPERFAMILY SSF46557 4 78 5.1E-24 T 21-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 7 157 9.7E-54 T 21-04-2016 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 Gene3D G3DSA:1.10.287.180 4 77 4.7E-28 T 21-04-2016 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 HSISS4_RS01170 c0cda494c19adfaa6aaf2c802e2d8154 160 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 122 138 - T 21-04-2016 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 PANTHER PTHR24220:SF577 5 216 2.1E-103 T 21-04-2016 HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 Pfam PF00005 ABC transporter 24 166 8.7E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 Gene3D G3DSA:3.40.50.300 4 216 5.0E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 SUPERFAMILY SSF52540 4 219 3.7E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 PANTHER PTHR24220 5 216 2.1E-103 T 21-04-2016 HSISS4_RS07710 51e5baa1faeb2a3b667df26b4ae9b650 233 SMART SM00382 32 215 2.2E-15 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03585 b4079244a966ed5b1405f8e71c7d73fc 331 Pfam PF13354 Beta-lactamase enzyme family 100 292 2.9E-18 T 21-04-2016 HSISS4_RS03585 b4079244a966ed5b1405f8e71c7d73fc 331 Gene3D G3DSA:3.40.710.10 69 307 2.7E-49 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS03585 b4079244a966ed5b1405f8e71c7d73fc 331 SUPERFAMILY SSF56601 73 308 1.38E-39 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 SMART SM00448 2 112 6.4E-35 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-22 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 3.5E-18 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 SMART SM00862 145 220 4.0E-17 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 SUPERFAMILY SSF52172 1 178 1.96E-36 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 Gene3D G3DSA:1.10.10.10 123 221 4.9E-25 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 PANTHER PTHR26402:SF518 2 222 9.6E-104 T 21-04-2016 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 Gene3D G3DSA:3.40.50.2300 2 121 3.7E-34 T 21-04-2016 HSISS4_RS05670 715587c6385d98de8d5485db27413d3f 224 PANTHER PTHR26402 2 222 9.6E-104 T 21-04-2016 HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 Gene3D G3DSA:3.30.70.1450 150 219 6.9E-9 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 PANTHER PTHR16254 8 160 8.1E-42 T 21-04-2016 HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 Pfam PF02254 TrkA-N domain 8 121 5.0E-25 T 21-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 SUPERFAMILY SSF116726 133 216 8.37E-11 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 SUPERFAMILY SSF51735 6 135 4.69E-32 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01410 61ed6593b050e0c317b3f78c45e38ad9 223 Gene3D G3DSA:3.40.50.720 6 138 5.5E-34 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01215 82ace2c653047a9369641be23d6fe9a8 83 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 1 62 1.0E-29 T 21-04-2016 IPR005359 Protein with unknown function UPF0154 HSISS4_RS01215 82ace2c653047a9369641be23d6fe9a8 83 Pfam PF03672 Uncharacterised protein family (UPF0154) 11 68 2.3E-22 T 21-04-2016 IPR005359 Protein with unknown function UPF0154 HSISS4_RS01215 82ace2c653047a9369641be23d6fe9a8 83 PANTHER PTHR41297 2 81 9.8E-26 T 21-04-2016 HSISS4_RS03550 eef7486dbdaffe86721b8606813cc843 279 Gene3D G3DSA:1.10.3470.10 13 262 2.0E-10 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS03550 eef7486dbdaffe86721b8606813cc843 279 PANTHER PTHR30477 4 270 2.0E-116 T 21-04-2016 HSISS4_RS03550 eef7486dbdaffe86721b8606813cc843 279 Pfam PF00950 ABC 3 transport family 12 266 4.9E-85 T 21-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 HSISS4_RS03550 eef7486dbdaffe86721b8606813cc843 279 SUPERFAMILY SSF81345 9 262 4.05E-41 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS03550 eef7486dbdaffe86721b8606813cc843 279 PANTHER PTHR30477:SF13 4 270 2.0E-116 T 21-04-2016 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 Gene3D G3DSA:3.90.230.10 1 281 8.1E-78 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 PANTHER PTHR10804:SF108 128 283 2.4E-168 T 21-04-2016 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 PANTHER PTHR10804:SF108 1 101 2.4E-168 T 21-04-2016 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 PANTHER PTHR10804 128 283 2.4E-168 T 21-04-2016 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 PANTHER PTHR10804 1 101 2.4E-168 T 21-04-2016 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 129 279 4.6E-51 T 21-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 Pfam PF00557 Metallopeptidase family M24 11 100 1.8E-8 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 Pfam PF00557 Metallopeptidase family M24 130 271 1.9E-28 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 SUPERFAMILY SSF55920 1 101 1.34E-67 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 SUPERFAMILY SSF55920 129 281 1.34E-67 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS07490 91b011eec46ee1d3f2eb571f3631433b 286 Hamap MF_01974 Methionine aminopeptidase [map]. 2 280 35.343 T 21-04-2016 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 Pfam PF00266 Aminotransferase class-V 3 349 2.2E-45 T 21-04-2016 IPR000192 Aminotransferase class V domain HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 Gene3D G3DSA:3.90.1150.10 261 363 3.0E-37 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 SUPERFAMILY SSF53383 3 363 1.62E-99 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 1 363 48.376 T 21-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 PANTHER PTHR21152 3 364 7.8E-152 T 21-04-2016 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 PIRSF PIRSF000525 1 364 3.2E-141 T 21-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 Gene3D G3DSA:3.40.640.10 16 258 6.3E-96 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 3 362 2.8E-144 T 21-04-2016 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|UniPathway: UPA00135|UniPathway: UPA00244 HSISS4_RS07315 7950798917cff0761401e31f9f42a730 364 PANTHER PTHR21152:SF1 3 364 7.8E-152 T 21-04-2016 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Pfam PF07499 RuvA, C-terminal domain 152 195 3.5E-10 T 21-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 SUPERFAMILY SSF47781 65 136 1.22E-19 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 PANTHER PTHR33796 2 196 3.9E-66 T 21-04-2016 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 2 195 6.3E-49 T 21-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Pfam PF01330 RuvA N terminal domain 1 61 2.7E-18 T 21-04-2016 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 SUPERFAMILY SSF50249 1 62 6.85E-16 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 28.884 T 21-04-2016 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Gene3D G3DSA:1.10.150.20 66 139 4.2E-27 T 21-04-2016 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Gene3D G3DSA:2.40.50.140 1 65 1.1E-21 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 SMART SM00278 107 126 8.0 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 SMART SM00278 72 91 2.0 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 SUPERFAMILY SSF46929 149 195 5.62E-10 T 21-04-2016 IPR011114 DNA helicase, Holliday junction RuvA type, domain III, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Gene3D G3DSA:1.10.8.10 149 195 3.3E-13 T 21-04-2016 HSISS4_RS00330 6b65e187c6362e5a7d60b2d57657c0b2 196 Pfam PF14520 Helix-hairpin-helix domain 71 127 1.3E-11 T 21-04-2016 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 Pfam PF01895 PhoU domain 19 104 5.2E-23 T 21-04-2016 IPR026022 PhoU domain HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 Pfam PF01895 PhoU domain 121 206 1.9E-16 T 21-04-2016 IPR026022 PhoU domain HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 215 3.9E-74 T 21-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 Gene3D G3DSA:1.20.58.220 3 110 4.6E-35 T 21-04-2016 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 Gene3D G3DSA:1.20.58.220 111 216 8.0E-27 T 21-04-2016 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 PANTHER PTHR10010 1 216 2.4E-54 T 21-04-2016 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 SUPERFAMILY SSF109755 3 216 3.66E-63 T 21-04-2016 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 PANTHER PTHR10010:SF14 1 216 2.4E-54 T 21-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HSISS4_RS04870 a28b3b28149e208849022bd7a7d7aafa 217 PIRSF PIRSF003107 1 217 1.3E-62 T 21-04-2016 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 126 5.8E-32 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 123 4.4E-36 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 5.3E-6 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 5.3E-6 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 5.3E-6 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 SUPERFAMILY SSF81330 10 120 2.75E-27 T 21-04-2016 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 PANTHER PTHR30266 1 126 1.6E-38 T 21-04-2016 HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 21-04-2016 IPR019823 Large-conductance mechanosensitive channel, conserved site HSISS4_RS07150 c68891ca3cdc7832ff88c45e15445da9 126 PANTHER PTHR30266:SF2 1 126 1.6E-38 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PANTHER PTHR24078:SF190 2 365 1.0E-169 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Pfam PF00684 DnaJ central domain 146 210 9.6E-14 T 21-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SMART SM00271 4 61 2.8E-29 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SUPERFAMILY SSF57938 133 213 1.57E-19 T 21-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SUPERFAMILY SSF49493 113 137 3.66E-20 T 21-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SUPERFAMILY SSF49493 216 269 3.66E-20 T 21-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Gene3D G3DSA:2.60.260.20 209 257 5.5E-23 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Gene3D G3DSA:2.60.260.20 260 337 2.8E-22 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Gene3D G3DSA:2.60.260.20 110 135 5.5E-23 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 373 39.785 T 21-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PANTHER PTHR24078 2 365 1.0E-169 T 21-04-2016 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 353 9.9E-140 T 21-04-2016 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Gene3D G3DSA:1.10.287.110 1 105 8.8E-37 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Pfam PF00226 DnaJ domain 5 66 1.8E-25 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Gene3D G3DSA:2.10.230.10 136 208 1.2E-20 T 21-04-2016 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SUPERFAMILY SSF49493 262 347 2.88E-23 T 21-04-2016 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 Pfam PF01556 DnaJ C terminal domain 119 336 7.2E-42 T 21-04-2016 IPR002939 Chaperone DnaJ, C-terminal HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 21-04-2016 IPR018253 DnaJ domain, conserved site HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 SUPERFAMILY SSF46565 1 104 1.31E-35 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PRINTS PR00625 DnaJ domain signature 25 40 1.2E-29 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PRINTS PR00625 DnaJ domain signature 41 61 1.2E-29 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PRINTS PR00625 DnaJ domain signature 61 80 1.2E-29 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS00680 d82465170211a3c6d09f6b915aba61c5 377 PRINTS PR00625 DnaJ domain signature 7 25 1.2E-29 T 21-04-2016 IPR001623 DnaJ domain HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 SMART SM00898 2 116 1.0E-46 T 21-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 PANTHER PTHR22993:SF15 1 273 1.4E-111 T 21-04-2016 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 ProSitePatterns PS01242 Zinc finger FPG-type signature. 247 271 - T 21-04-2016 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 SUPERFAMILY SSF81624 2 141 3.79E-40 T 21-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 271 3.3E-104 T 21-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.2E-31 T 21-04-2016 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Pfam PF06827 Zinc finger found in FPG and IleRS 244 273 3.7E-13 T 21-04-2016 IPR010663 Zinc finger, FPG/IleRS-type HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 SUPERFAMILY SSF57716 220 272 1.57E-17 T 21-04-2016 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 272 42.444 T 21-04-2016 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Gene3D G3DSA:3.20.190.10 2 127 2.2E-36 T 21-04-2016 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Gene3D G3DSA:1.10.8.50 132 272 7.1E-49 T 21-04-2016 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 PANTHER PTHR22993 1 273 1.4E-111 T 21-04-2016 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 SMART SM01232 132 224 2.0E-38 T 21-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 132 222 1.2E-29 T 21-04-2016 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 HSISS4_RS02920 911da9d56704d6fcd708c09e099d18bf 273 SUPERFAMILY SSF46946 131 221 1.44E-27 T 21-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Gene3D G3DSA:3.30.70.260 661 735 2.5E-10 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 736 7.1E-237 T 21-04-2016 IPR004811 RelA/SpoT family GO:0015969 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 PANTHER PTHR21262:SF0 10 739 0.0 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SUPERFAMILY SSF109604 9 196 3.01E-76 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Pfam PF02824 TGS domain 395 454 9.0E-22 T 21-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Pfam PF04607 Region found in RelA / SpoT proteins 240 348 3.3E-37 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SUPERFAMILY SSF81301 199 370 1.14E-62 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Pfam PF13291 ACT domain 658 736 2.7E-18 T 21-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 PANTHER PTHR21262 10 739 0.0 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SMART SM00954 240 349 1.9E-62 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Gene3D G3DSA:3.10.20.30 394 455 4.0E-22 T 21-04-2016 IPR012675 Beta-grasp domain HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SUPERFAMILY SSF81271 382 455 2.4E-20 T 21-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SUPERFAMILY SSF55021 661 736 6.25E-8 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Gene3D G3DSA:3.30.460.10 199 329 1.0E-47 T 21-04-2016 HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 SMART SM00471 46 158 6.6E-9 T 21-04-2016 IPR003607 HD/PDEase domain HSISS4_RS00780 eabb7519615b6a66d4b611d2dd7f78c9 739 Pfam PF13328 HD domain 31 180 4.7E-50 T 21-04-2016 IPR003607 HD/PDEase domain HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PANTHER PTHR20854 1 238 1.2E-52 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 SUPERFAMILY SSF56655 2 250 5.89E-59 T 21-04-2016 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 59 75 3.9E-21 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 3.9E-21 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 37 57 3.9E-21 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 3.9E-21 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PRINTS PR00377 Inositol monophosphatase superfamily signature 171 192 3.9E-21 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 Gene3D G3DSA:3.40.190.80 156 250 1.1E-14 T 21-04-2016 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 PANTHER PTHR20854:SF4 1 238 1.2E-52 T 21-04-2016 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 Pfam PF00459 Inositol monophosphatase family 5 235 8.3E-42 T 21-04-2016 IPR000760 Inositol monophosphatase GO:0046854 HSISS4_RS04905 b8819c2b5959a4d06c142aedc608e8e1 255 Gene3D G3DSA:3.30.540.10 3 154 2.5E-37 T 21-04-2016 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PANTHER PTHR11817:SF3 1 16 7.2E-194 T 21-04-2016 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PANTHER PTHR11817:SF3 38 499 7.2E-194 T 21-04-2016 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 ProSitePatterns PS00110 Pyruvate kinase active site signature. 243 255 - T 21-04-2016 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Gene3D G3DSA:3.20.20.60 197 354 6.7E-98 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Gene3D G3DSA:3.20.20.60 4 94 6.7E-98 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 37 499 1.0E-151 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PANTHER PTHR11817 1 16 7.2E-194 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PANTHER PTHR11817 38 499 7.2E-194 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 SUPERFAMILY SSF52935 351 499 3.92E-41 T 21-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Gene3D G3DSA:2.40.33.10 95 196 4.5E-21 T 21-04-2016 IPR015806 Pyruvate kinase, beta-barrel insert domain GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 341 357 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 322 340 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 245 271 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 297 321 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 81 97 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 272 296 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 PRINTS PR01050 Pyruvate kinase family signature 214 228 5.2E-67 T 21-04-2016 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Pfam PF00224 Pyruvate kinase, barrel domain 3 371 1.9E-146 T 21-04-2016 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 SUPERFAMILY SSF51621 2 96 7.33E-83 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 SUPERFAMILY SSF51621 184 366 7.33E-83 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Gene3D G3DSA:3.40.1380.20 355 500 3.0E-48 T 21-04-2016 IPR015794 Pyruvate kinase, alpha/beta GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 SUPERFAMILY SSF50800 92 194 1.2E-17 T 21-04-2016 IPR011037 Pyruvate kinase-like, insert domain HSISS4_RS04155 9c35bba323f3eebaeb145636bac8da97 500 Pfam PF02887 Pyruvate kinase, alpha/beta domain 385 496 1.9E-35 T 21-04-2016 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 109 138 - T 21-04-2016 IPR018239 NAD-dependent DNA ligase, active site HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SUPERFAMILY SSF52113 580 651 2.62E-20 T 21-04-2016 IPR001357 BRCT domain HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:1.10.287.610 2 64 5.2E-26 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SUPERFAMILY SSF56091 2 306 4.32E-112 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 394 420 1.3E-9 T 21-04-2016 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:1.10.150.20 421 489 3.4E-27 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 581 652 1.5E-14 T 21-04-2016 IPR001357 BRCT domain HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 306 6.9E-116 T 21-04-2016 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:1.10.150.20 490 570 2.6E-24 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF14520 Helix-hairpin-helix domain 432 487 2.1E-6 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 PANTHER PTHR23389 1 507 4.1E-180 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:2.40.50.140 308 379 2.3E-34 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 310 386 1.1E-35 T 21-04-2016 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Pfam PF12826 Helix-hairpin-helix motif 496 557 1.4E-20 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SUPERFAMILY SSF50249 306 387 5.82E-28 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SMART SM00278 466 485 6.5 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SMART SM00278 530 549 450.0 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SMART SM00278 432 451 2.4 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SUPERFAMILY SSF47781 391 571 5.93E-60 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 PANTHER PTHR23389:SF9 1 507 4.1E-180 T 21-04-2016 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Hamap MF_01588 DNA ligase [ligA]. 1 652 49.309 T 21-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SMART SM00292 579 652 4.4E-11 T 21-04-2016 IPR001357 BRCT domain HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:3.40.50.10190 579 652 1.4E-25 T 21-04-2016 IPR001357 BRCT domain HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 319 334 - T 21-04-2016 IPR033136 NAD-dependent DNA ligase, conserved site HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 11 647 1.0E-244 T 21-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 PIRSF PIRSF001604 1 652 2.1E-243 T 21-04-2016 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 SMART SM00532 2 434 2.0E-239 T 21-04-2016 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 HSISS4_RS07475 72493dcf354567287704f1f582496d98 652 Gene3D G3DSA:3.30.470.30 113 239 7.4E-44 T 21-04-2016 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 Gene3D G3DSA:3.40.50.1100 101 180 2.6E-19 T 21-04-2016 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 PIRSF PIRSF001413 1 401 2.6E-165 T 21-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 SUPERFAMILY SSF53686 6 392 7.99E-143 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 395 51.847 T 21-04-2016 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 382 1.2E-44 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 Gene3D G3DSA:3.40.50.1100 181 397 2.3E-86 T 21-04-2016 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 PANTHER PTHR10314:SF3 10 402 1.0E-231 T 21-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 84 98 - T 21-04-2016 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 PANTHER PTHR10314 10 402 1.0E-231 T 21-04-2016 HSISS4_RS07650 04f305108281ca997f1f95ddf4070225 402 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 10 393 5.2E-191 T 21-04-2016 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 PANTHER PTHR10285 268 300 9.0E-129 T 21-04-2016 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 PANTHER PTHR10285 1 252 9.0E-129 T 21-04-2016 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 Hamap MF_00215 Pantothenate kinase [coaA]. 1 306 145.359 T 21-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 PANTHER PTHR10285:SF7 268 300 9.0E-129 T 21-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 PANTHER PTHR10285:SF7 1 252 9.0E-129 T 21-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 86 230 3.9E-12 T 21-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 Gene3D G3DSA:3.40.50.300 7 304 2.4E-100 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 SUPERFAMILY SSF52540 3 305 1.02E-69 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 PIRSF PIRSF000545 1 306 5.0E-135 T 21-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HSISS4_RS05655 09027c2c40c40cd62a0cf17a8e289860 306 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 9 306 1.3E-98 T 21-04-2016 IPR004566 Bacterial pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961|UniPathway: UPA00241 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Pfam PF12848 ABC transporter 223 292 8.2E-9 T 21-04-2016 IPR032781 ABC-transporter extension domain HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Pfam PF00005 ABC transporter 333 467 2.8E-20 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Pfam PF00005 ABC transporter 20 184 1.6E-20 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Pfam PF16326 ABC transporter C-terminal domain 557 623 7.5E-16 T 21-04-2016 IPR032524 ABC transporter Uup, C-terminal GO:0003677 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 PANTHER PTHR19211 545 583 1.9E-190 T 21-04-2016 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 PANTHER PTHR19211 1 524 1.9E-190 T 21-04-2016 HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 SMART SM00382 342 521 3.3E-6 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 SMART SM00382 28 229 4.7E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Gene3D G3DSA:3.40.50.300 6 281 2.4E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 Gene3D G3DSA:3.40.50.300 318 556 5.3E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 SUPERFAMILY SSF52540 6 239 1.38E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01945 7d4f681ca8c6c4c40ce255e7ca723250 626 SUPERFAMILY SSF52540 309 527 5.73E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 1 237 31.0 T 21-04-2016 IPR002876 Transcriptional regulator TACO1-like HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Pfam PF01709 Transcriptional regulator 4 235 2.7E-82 T 21-04-2016 IPR002876 Transcriptional regulator TACO1-like HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Gene3D G3DSA:1.10.10.200 1 77 5.6E-29 T 21-04-2016 IPR017856 Integrase, N-terminal zinc-binding domain-like HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 PANTHER PTHR12532:SF4 1 237 4.4E-147 T 21-04-2016 HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Gene3D G3DSA:3.30.70.980 132 203 1.3E-24 T 21-04-2016 IPR026564 Transcriptional regulator TACO1-like, domain 3 HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Hamap MF_00918 Probable transcriptional regulatory protein YeeN [yeeN]. 1 238 61.487 T 21-04-2016 IPR026562 Probable transcriptional regulatory protein YeeN HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 PANTHER PTHR12532 1 237 4.4E-147 T 21-04-2016 IPR002876 Transcriptional regulator TACO1-like HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 4.7E-71 T 21-04-2016 IPR002876 Transcriptional regulator TACO1-like HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Gene3D G3DSA:3.30.1270.10 210 236 7.0E-35 T 21-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 Gene3D G3DSA:3.30.1270.10 81 131 7.0E-35 T 21-04-2016 IPR026563 Transcriptional regulator TACO1-like, domain 2 HSISS4_RS00945 bed2ee89e6fb495c7a4e1ab2adc2bee2 238 SUPERFAMILY SSF75625 1 235 3.14E-81 T 21-04-2016 IPR029072 YebC-like HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 PANTHER PTHR40039:SF1 2 422 1.8E-126 T 21-04-2016 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 PANTHER PTHR40039 2 422 1.8E-126 T 21-04-2016 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 Pfam PF04914 DltD C-terminal region 265 392 1.0E-51 T 21-04-2016 IPR006998 DltD, C-terminal UniPathway: UPA00556 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 TIGRFAM TIGR04092 LTA_DltD: D-alanyl-lipoteichoic acid biosynthesis protein DltD 9 391 3.0E-133 T 21-04-2016 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD UniPathway: UPA00556 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 PIRSF PIRSF021438 1 394 1.6E-123 T 21-04-2016 IPR023896 D-alanyl-lipoteichoic acid biosynthesis DltD UniPathway: UPA00556 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 Pfam PF04918 DltD central region 99 263 4.5E-48 T 21-04-2016 IPR007002 DltD, central domain UniPathway: UPA00556 HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 SUPERFAMILY SSF52266 289 391 8.06E-5 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS05725 a4abd96e240f36a02faec2048dfaafa2 422 Pfam PF04915 DltD N-terminal region 37 98 6.1E-25 T 21-04-2016 IPR006999 DltD, N-terminal UniPathway: UPA00556 HSISS4_RS02040 421f129ca0e3639df256a288414c4500 354 Gene3D G3DSA:3.40.50.300 110 315 1.5E-88 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02040 421f129ca0e3639df256a288414c4500 354 Pfam PF02562 PhoH-like protein 112 315 6.4E-95 T 21-04-2016 IPR003714 PhoH-like protein GO:0005524 HSISS4_RS02040 421f129ca0e3639df256a288414c4500 354 PANTHER PTHR30473 6 338 4.8E-163 T 21-04-2016 HSISS4_RS02040 421f129ca0e3639df256a288414c4500 354 PANTHER PTHR30473:SF1 6 338 4.8E-163 T 21-04-2016 HSISS4_RS02040 421f129ca0e3639df256a288414c4500 354 SUPERFAMILY SSF52540 111 312 5.31E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 SMART SM00062 35 270 1.5E-40 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 Gene3D G3DSA:3.40.190.10 113 214 2.9E-19 T 21-04-2016 HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 PANTHER PTHR18966:SF208 26 271 5.0E-21 T 21-04-2016 HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 Gene3D G3DSA:3.40.190.10 226 271 5.9E-31 T 21-04-2016 HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 Gene3D G3DSA:3.40.190.10 32 112 5.9E-31 T 21-04-2016 HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 PANTHER PTHR18966 26 271 5.0E-21 T 21-04-2016 HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 268 5.2E-44 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS08010 aa6f202238f83539a8509ac99ccd3924 276 SUPERFAMILY SSF53850 1 270 1.27E-45 T 21-04-2016 HSISS4_RS02480 67f94c0ba6d2f9666e943bafa664b08a 417 PANTHER PTHR32347 1 398 1.1E-60 T 21-04-2016 HSISS4_RS02480 67f94c0ba6d2f9666e943bafa664b08a 417 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 51 394 1.2E-28 T 21-04-2016 IPR006143 RND efflux pump, membrane fusion protein GO:0016020|GO:0055085 HSISS4_RS02480 67f94c0ba6d2f9666e943bafa664b08a 417 PANTHER PTHR32347:SF14 1 398 1.1E-60 T 21-04-2016 HSISS4_RS02480 67f94c0ba6d2f9666e943bafa664b08a 417 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 61 275 6.5E-13 T 21-04-2016 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 Gene3D G3DSA:1.10.1660.10 15 105 1.4E-21 T 21-04-2016 HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 SMART SM00422 14 82 1.0E-19 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 ProSitePatterns PS00552 MerR-type HTH domain signature. 17 39 - T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 PANTHER PTHR30204:SF8 6 109 2.2E-34 T 21-04-2016 HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 SUPERFAMILY SSF46955 14 90 7.33E-20 T 21-04-2016 IPR009061 Putative DNA-binding domain HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 PANTHER PTHR30204 6 109 2.2E-34 T 21-04-2016 HSISS4_RS08560 5085b6688756e4754d433769d0e02582 124 Pfam PF13411 MerR HTH family regulatory protein 15 77 1.2E-19 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 PANTHER PTHR30175 22 396 1.5E-13 T 21-04-2016 HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 PANTHER PTHR30175 412 539 1.5E-13 T 21-04-2016 HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 SUPERFAMILY SSF75005 42 377 7.22E-43 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 PANTHER PTHR30175:SF0 22 396 1.5E-13 T 21-04-2016 HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 PANTHER PTHR30175:SF0 412 539 1.5E-13 T 21-04-2016 HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 Gene3D G3DSA:2.60.120.560 423 571 9.8E-5 T 21-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 45 376 4.3E-40 T 21-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal HSISS4_RS01605 489af8b550f3c08caee1fdc3b2a1494e 573 SMART SM00640 45 537 8.5E-14 T 21-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PRINTS PR01607 Apyrase family signature 3 21 8.2E-15 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PRINTS PR01607 Apyrase family signature 320 343 8.2E-15 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PRINTS PR01607 Apyrase family signature 184 207 8.2E-15 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PRINTS PR01607 Apyrase family signature 212 232 8.2E-15 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PRINTS PR01607 Apyrase family signature 165 182 8.2E-15 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PIRSF PIRSF036361 1 445 6.9E-160 T 21-04-2016 IPR011240 Phosphoesterase-related protein YunD HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PANTHER PTHR11575 4 441 1.6E-95 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 PANTHER PTHR11575:SF23 4 441 1.6E-95 T 21-04-2016 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 SUPERFAMILY SSF56300 4 271 4.16E-59 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 SUPERFAMILY SSF55816 289 445 1.43E-11 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 ProSitePatterns PS00785 5'-nucleotidase signature 1. 5 17 - T 21-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 Gene3D G3DSA:3.90.780.10 288 445 4.5E-8 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 Gene3D G3DSA:3.60.21.10 4 271 4.9E-54 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS08120 1fb6a6fdd04520132f75871ff0e27aea 451 Pfam PF00149 Calcineurin-like phosphoesterase 5 201 1.5E-12 T 21-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HSISS4_RS03650 ed8b60c2350db38c322d363097b07627 194 Hamap MF_01197 Cell division protein SepF [sepF]. 4 179 19.269 T 21-04-2016 IPR023052 Cell division protein SepF GO:0090529 HSISS4_RS03650 ed8b60c2350db38c322d363097b07627 194 Pfam PF04472 Protein of unknown function (DUF552) 102 171 1.5E-17 T 21-04-2016 IPR007561 Cell division protein SepF/SepF-related GO:0000917 HSISS4_RS03650 ed8b60c2350db38c322d363097b07627 194 PANTHER PTHR35798 1 194 3.3E-23 T 21-04-2016 HSISS4_RS03650 ed8b60c2350db38c322d363097b07627 194 PANTHER PTHR35798:SF1 1 194 3.3E-23 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 Pfam PF00480 ROK family 220 300 2.0E-6 T 21-04-2016 IPR000600 ROK family HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 Pfam PF00480 ROK family 3 141 1.2E-21 T 21-04-2016 IPR000600 ROK family HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 SUPERFAMILY SSF53067 2 302 1.46E-40 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 Gene3D G3DSA:3.30.420.40 2 99 1.3E-27 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 PANTHER PTHR18964 3 141 8.9E-40 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 Gene3D G3DSA:3.30.420.40 101 302 9.6E-37 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 PANTHER PTHR18964 166 296 8.9E-40 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 PANTHER PTHR18964:SF133 3 141 8.9E-40 T 21-04-2016 HSISS4_RS05390 bbaed2ea615694e3edd0419c6159383a 306 PANTHER PTHR18964:SF133 166 296 8.9E-40 T 21-04-2016 HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 110 1.6E-29 T 21-04-2016 IPR006504 Transcriptional regulator Spx/MgsR HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 SUPERFAMILY SSF52833 1 110 1.71E-31 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 PANTHER PTHR30041:SF3 1 109 2.1E-33 T 21-04-2016 HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 Pfam PF03960 ArsC family 9 108 1.0E-13 T 21-04-2016 IPR006660 Arsenate reductase-like HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 Gene3D G3DSA:3.40.30.10 1 110 6.2E-38 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS07295 3db86b6fd743cb03a3a5d17f1d002e64 117 PANTHER PTHR30041 1 109 2.1E-33 T 21-04-2016 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SUPERFAMILY SSF48452 266 403 2.66E-20 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SUPERFAMILY SSF48452 14 102 2.66E-20 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 PANTHER PTHR23083:SF412 2 409 4.6E-47 T 21-04-2016 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SUPERFAMILY SSF48452 173 231 2.66E-20 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SUPERFAMILY SSF48452 99 202 3.41E-7 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Gene3D G3DSA:1.25.40.10 184 216 1.4E-8 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Gene3D G3DSA:1.25.40.10 217 320 8.2E-11 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Gene3D G3DSA:1.25.40.10 78 183 5.0E-14 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Gene3D G3DSA:1.25.40.10 331 398 4.5E-6 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Gene3D G3DSA:1.25.40.10 13 77 2.7E-4 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 Pfam PF13181 Tetratricopeptide repeat 169 199 1.8E-6 T 21-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 PANTHER PTHR23083 2 409 4.6E-47 T 21-04-2016 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SMART SM00028 130 160 210.0 T 21-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SMART SM00028 167 200 4.5E-4 T 21-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SMART SM00028 268 301 180.0 T 21-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HSISS4_RS04465 af222f1868bc6c0b3a90f6ee8d0642cd 409 SMART SM00028 332 368 360.0 T 21-04-2016 IPR019734 Tetratricopeptide repeat GO:0005515 HSISS4_RS05425 09f259127cda46ed02b99c213bce0511 110 Gene3D G3DSA:1.10.10.10 1 106 1.7E-41 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05425 09f259127cda46ed02b99c213bce0511 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 3 101 2.8E-42 T 21-04-2016 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HSISS4_RS05425 09f259127cda46ed02b99c213bce0511 110 SUPERFAMILY SSF88659 4 105 7.66E-33 T 21-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS05425 09f259127cda46ed02b99c213bce0511 110 Hamap MF_00245 UPF0122 protein . 3 104 20.99 T 21-04-2016 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like HSISS4_RS05425 09f259127cda46ed02b99c213bce0511 110 PANTHER PTHR40083 2 110 1.5E-42 T 21-04-2016 HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 Pfam PF00005 ABC transporter 17 160 2.0E-26 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 PANTHER PTHR24220:SF160 3 243 2.4E-86 T 21-04-2016 HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 SUPERFAMILY SSF52540 2 223 3.86E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 SMART SM00382 26 208 1.5E-5 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 PANTHER PTHR24220 3 243 2.4E-86 T 21-04-2016 HSISS4_RS08200 2a791d2b0e7c2a5d60d0608e50fce8b7 243 Gene3D G3DSA:3.40.50.300 1 223 1.1E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 TIGRFAM TIGR00545 lipoyltrans: lipoyltransferase and lipoate-protein ligase 5 321 1.7E-96 T 21-04-2016 IPR004562 Lipoyltransferase/lipoate-protein ligase GO:0009249 UniPathway: UPA00537|UniPathway: UPA00537 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 243 326 2.1E-25 T 21-04-2016 IPR019491 Lipoate protein ligase, C-terminal UniPathway: UPA00537|UniPathway: UPA00537 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 Gene3D G3DSA:3.90.1550.10 1 241 5.3E-87 T 21-04-2016 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 45 154 8.0E-9 T 21-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 PANTHER PTHR12561:SF3 1 328 9.7E-115 T 21-04-2016 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 SUPERFAMILY SSF82649 242 328 4.13E-25 T 21-04-2016 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 PANTHER PTHR12561 1 328 9.7E-115 T 21-04-2016 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 SUPERFAMILY SSF55681 1 241 5.47E-78 T 21-04-2016 HSISS4_RS04855 283f0c24f3b40d1d03db406f92696945 329 Gene3D G3DSA:3.30.390.50 242 328 2.4E-30 T 21-04-2016 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 Hamap MF_01568 UPF0374 protein . 1 175 49.33 T 21-04-2016 IPR016882 Uncharacterised protein family UPF0374 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 PANTHER PTHR39159 1 176 6.3E-71 T 21-04-2016 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 PANTHER PTHR39159:SF1 1 176 6.3E-71 T 21-04-2016 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 PIRSF PIRSF028345 1 177 7.8E-77 T 21-04-2016 IPR016882 Uncharacterised protein family UPF0374 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 Gene3D G3DSA:2.40.380.10 4 170 7.5E-46 T 21-04-2016 IPR007295 Domain of unknown function DUF402 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 Pfam PF04167 Protein of unknown function (DUF402) 60 124 1.1E-16 T 21-04-2016 IPR007295 Domain of unknown function DUF402 HSISS4_RS01750 229a09731bc5143b8843be44717498e1 177 SUPERFAMILY SSF159234 3 170 1.83E-32 T 21-04-2016 HSISS4_RS09410 5ca779d3c4decc68e2bea7f09d3f95a9 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 1.2E-35 T 21-04-2016 IPR009309 Uncharacterised protein family UPF0297 HSISS4_RS09410 5ca779d3c4decc68e2bea7f09d3f95a9 88 PANTHER PTHR40067 2 88 5.5E-44 T 21-04-2016 HSISS4_RS09410 5ca779d3c4decc68e2bea7f09d3f95a9 88 PIRSF PIRSF037258 1 87 4.2E-43 T 21-04-2016 IPR009309 Uncharacterised protein family UPF0297 HSISS4_RS09410 5ca779d3c4decc68e2bea7f09d3f95a9 88 Hamap MF_01507 UPF0297 protein . 1 84 26.684 T 21-04-2016 IPR009309 Uncharacterised protein family UPF0297 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 6 77 2.9E-35 T 21-04-2016 IPR019984 Ribosomal protein S17, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 PRINTS PR00973 Ribosomal protein S17 family signature 67 74 1.6E-11 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 PRINTS PR00973 Ribosomal protein S17 family signature 57 67 1.6E-11 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 PRINTS PR00973 Ribosomal protein S17 family signature 25 48 1.6E-11 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 5 77 6.0E-35 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 Gene3D G3DSA:2.40.50.140 6 83 8.1E-35 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 ProSitePatterns PS00056 Ribosomal protein S17 signature. 57 69 - T 21-04-2016 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 4 82 24.436 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 Pfam PF00366 Ribosomal protein S17 11 78 1.5E-32 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 SUPERFAMILY SSF50249 6 83 3.08E-32 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09305 c19f6cf13f3b75407208318f036bcc47 86 PANTHER PTHR10744 3 85 4.8E-41 T 21-04-2016 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 Gene3D G3DSA:3.20.20.70 5 250 8.4E-84 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 47 65 - T 21-04-2016 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 SUPERFAMILY SSF51366 9 251 3.41E-74 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 4 252 31.168 T 21-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 PANTHER PTHR22854 5 250 1.4E-86 T 21-04-2016 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 Pfam PF00218 Indole-3-glycerol phosphate synthase 11 250 3.8E-81 T 21-04-2016 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48|UniPathway: UPA00035 HSISS4_RS07660 2360a2f5cd1f9daa30b9ed435bd43c1d 255 PANTHER PTHR22854:SF2 5 250 1.4E-86 T 21-04-2016 HSISS4_RS04615 a120306d99325a0b1673326fae0ff505 382 Pfam PF13439 Glycosyltransferase Family 4 15 180 2.4E-19 T 21-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HSISS4_RS04615 a120306d99325a0b1673326fae0ff505 382 SUPERFAMILY SSF53756 11 381 1.05E-71 T 21-04-2016 HSISS4_RS04615 a120306d99325a0b1673326fae0ff505 382 PANTHER PTHR12526 3 381 4.5E-54 T 21-04-2016 HSISS4_RS04615 a120306d99325a0b1673326fae0ff505 382 Pfam PF00534 Glycosyl transferases group 1 192 360 1.5E-31 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS04615 a120306d99325a0b1673326fae0ff505 382 Gene3D G3DSA:3.40.50.2000 167 359 7.5E-29 T 21-04-2016 HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 Pfam PF02653 Branched-chain amino acid transport system / permease component 353 622 2.3E-29 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 SUPERFAMILY SSF53822 34 284 1.84E-14 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 Gene3D G3DSA:3.40.50.2300 29 155 1.1E-57 T 21-04-2016 HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 PANTHER PTHR32196 293 646 1.2E-76 T 21-04-2016 HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 Pfam PF04392 ABC transporter substrate binding protein 31 310 5.3E-92 T 21-04-2016 IPR007487 ABC transporter, substrate-binding protein HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 Gene3D G3DSA:3.40.50.2300 156 286 4.5E-50 T 21-04-2016 HSISS4_RS00975 eac5f55317788b8145fa8adb516fce89 646 PANTHER PTHR32196:SF27 293 646 1.2E-76 T 21-04-2016 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 SUPERFAMILY SSF53223 1 121 1.92E-41 T 21-04-2016 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PANTHER PTHR10025 1 280 3.5E-157 T 21-04-2016 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 Gene3D G3DSA:3.40.50.720 139 263 1.2E-56 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 21-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 2 282 39.401 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 9.6E-73 T 21-04-2016 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 SUPERFAMILY SSF51735 122 280 5.49E-53 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 4 120 1.2E-40 T 21-04-2016 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 21-04-2016 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 6.2E-85 T 21-04-2016 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0003824|GO:0004488|GO:0009396|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|UniPathway: UPA00193 HSISS4_RS02880 cc02dae181a7fb4f7747c3122a6f6a3d 284 Gene3D G3DSA:3.40.192.10 6 138 8.9E-51 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 SMART SM00839 205 448 1.7E-85 T 21-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Gene3D G3DSA:1.10.285.10 375 450 2.8E-27 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Gene3D G3DSA:1.10.285.10 6 68 6.4E-29 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PANTHER PTHR11606:SF4 6 450 2.2E-250 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PANTHER PTHR11606 6 450 2.2E-250 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 448 5.3E-84 T 21-04-2016 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 SUPERFAMILY SSF53223 7 197 8.0E-75 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Gene3D G3DSA:3.40.50.720 210 374 2.7E-57 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 SUPERFAMILY SSF51735 203 449 4.53E-72 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PIRSF PIRSF000185 22 450 6.5E-118 T 21-04-2016 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Gene3D G3DSA:3.40.192.10 69 189 4.7E-64 T 21-04-2016 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 58 186 2.6E-51 T 21-04-2016 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 115 129 1.8E-29 T 21-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 1.8E-29 T 21-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 374 385 1.8E-29 T 21-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HSISS4_RS01965 39f503652b02398d1ca6feca1b032c84 450 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 1.8E-29 T 21-04-2016 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 159 181 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 248 267 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 17 34 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 304 324 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 327 348 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 366 388 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 392 411 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 82 101 7.1E-54 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PANTHER PTHR34448 2 413 1.3E-232 T 21-04-2016 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 Pfam PF02073 Thermophilic metalloprotease (M29) 7 411 1.4E-161 T 21-04-2016 IPR000787 Peptidase M29, aminopeptidase II GO:0004177|GO:0006508 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 PANTHER PTHR34448:SF3 2 413 1.3E-232 T 21-04-2016 HSISS4_RS00440 a47709864f26cbb0b7172d26bbbfce18 413 SUPERFAMILY SSF144052 6 413 1.7E-140 T 21-04-2016 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 PANTHER PTHR37038 5 274 1.7E-41 T 21-04-2016 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 68 286 9.6E-33 T 21-04-2016 IPR010057 Transcription activator MutR, C-terminal HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 Pfam PF01381 Helix-turn-helix 11 64 1.2E-9 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 SUPERFAMILY SSF47413 6 65 6.48E-14 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 Gene3D G3DSA:1.10.260.40 8 90 5.1E-12 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 SMART SM00530 10 64 1.6E-9 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00935 260a0677b455a9cdd5bff5c084def84a 290 PANTHER PTHR37038:SF1 5 274 1.7E-41 T 21-04-2016 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 475 90.206 T 21-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 Pfam PF01425 Amidase 24 463 1.4E-147 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 PANTHER PTHR11895 2 481 1.8E-216 T 21-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 SUPERFAMILY SSF75304 1 481 4.71E-156 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 ProSitePatterns PS00571 Amidases signature. 150 181 - T 21-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 475 2.4E-185 T 21-04-2016 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 Gene3D G3DSA:3.90.1300.10 3 482 3.4E-169 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS07870 0e8ced3aa7090c7a0f84392d2f088bbf 488 PANTHER PTHR11895:SF7 2 481 1.8E-216 T 21-04-2016 HSISS4_RS07480 f623a30d2ecbd2c34e5dff1ca018d72b 169 PANTHER PTHR40044 1 167 1.3E-33 T 21-04-2016 HSISS4_RS07480 f623a30d2ecbd2c34e5dff1ca018d72b 169 PANTHER PTHR40044:SF1 1 167 1.3E-33 T 21-04-2016 HSISS4_RS07480 f623a30d2ecbd2c34e5dff1ca018d72b 169 PIRSF PIRSF031501 1 169 4.9E-53 T 21-04-2016 IPR010387 Queuosine precursor transporter QueT GO:0005886 HSISS4_RS07480 f623a30d2ecbd2c34e5dff1ca018d72b 169 Pfam PF06177 QueT transporter 9 163 1.6E-35 T 21-04-2016 IPR010387 Queuosine precursor transporter QueT GO:0005886 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 Gene3D G3DSA:3.40.50.1000 1 74 2.0E-44 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 Gene3D G3DSA:3.40.50.1000 185 269 2.0E-44 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 PANTHER PTHR10000 1 271 6.1E-78 T 21-04-2016 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 ProSitePatterns PS01229 Hypothetical cof family signature 2. 219 241 - T 21-04-2016 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 PANTHER PTHR10000:SF27 1 271 6.1E-78 T 21-04-2016 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 238 4.9E-19 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 Gene3D G3DSA:3.30.1240.10 84 184 1.2E-21 T 21-04-2016 HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 SUPERFAMILY SSF56784 1 269 1.15E-57 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 2.3E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04665 cd0c6f71207712847ca1b498b56ebd42 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 265 9.5E-47 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 Gene3D G3DSA:3.40.50.2000 254 443 1.8E-16 T 21-04-2016 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 PANTHER PTHR12526 146 466 2.9E-44 T 21-04-2016 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 SUPERFAMILY SSF53756 162 465 1.15E-59 T 21-04-2016 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 SUPERFAMILY SSF53756 2 64 1.15E-59 T 21-04-2016 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 Pfam PF11997 Domain of unknown function (DUF3492) 1 257 1.1E-83 T 21-04-2016 IPR022622 Domain of unknown function DUF3492 HSISS4_RS04280 84d6d69bb065f48559e9dad82c822860 467 Pfam PF00534 Glycosyl transferases group 1 283 444 1.9E-24 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 SUPERFAMILY SSF53067 3 171 2.88E-35 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 SUPERFAMILY SSF100920 381 498 3.53E-12 T 21-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PRINTS PR00301 70kDa heat shock protein signature 186 196 6.6E-31 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PRINTS PR00301 70kDa heat shock protein signature 312 328 6.6E-31 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PRINTS PR00301 70kDa heat shock protein signature 4 17 6.6E-31 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PRINTS PR00301 70kDa heat shock protein signature 127 147 6.6E-31 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PRINTS PR00301 70kDa heat shock protein signature 343 363 6.6E-31 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Pfam PF00012 Hsp70 protein 5 85 9.1E-7 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Pfam PF00012 Hsp70 protein 99 515 1.3E-79 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:3.30.420.40 181 213 9.8E-26 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:3.30.420.40 297 336 9.8E-26 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 8 15 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 315 329 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 PANTHER PTHR19375 5 422 4.1E-87 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 180 193 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 SUPERFAMILY SSF53067 176 359 1.24E-43 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:3.30.420.40 103 180 2.3E-42 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:3.30.420.40 5 71 2.3E-42 T 21-04-2016 HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:2.60.34.10 349 525 1.4E-17 T 21-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HSISS4_RS08255 30bdab3f5a646f5b322d497ac294f783 532 Gene3D G3DSA:3.90.640.10 214 292 2.1E-7 T 21-04-2016 HSISS4_RS01395 aeeb9100dd609c4fb9aebb4d20f6a194 181 Pfam PF07155 ECF-type riboflavin transporter, S component 3 169 1.8E-47 T 21-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 HSISS4_RS01395 aeeb9100dd609c4fb9aebb4d20f6a194 181 PANTHER PTHR37815 1 181 3.2E-59 T 21-04-2016 HSISS4_RS01395 aeeb9100dd609c4fb9aebb4d20f6a194 181 Hamap MF_01572 UPF0397 protein . 2 181 25.44 T 21-04-2016 IPR022914 Protein of unknown function UPF0397 HSISS4_RS01395 aeeb9100dd609c4fb9aebb4d20f6a194 181 PANTHER PTHR37815:SF2 1 181 3.2E-59 T 21-04-2016 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 89 2.5E-12 T 21-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 SUPERFAMILY SSF51735 118 253 8.98E-30 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 PANTHER PTHR11695:SF294 16 334 5.1E-83 T 21-04-2016 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 Pfam PF13602 Zinc-binding dehydrogenase 187 330 1.6E-27 T 21-04-2016 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 SUPERFAMILY SSF50129 5 158 2.28E-35 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 Gene3D G3DSA:3.90.180.10 1 148 8.3E-44 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 SMART SM00829 13 330 5.2E-14 T 21-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 PANTHER PTHR11695 16 334 5.1E-83 T 21-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HSISS4_RS05200 915995897cb9ec33b2377c8413ac5feb 334 Gene3D G3DSA:3.40.50.720 149 243 3.0E-16 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 SUPERFAMILY SSF56601 1 296 5.33E-66 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 399 1.3E-11 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 2.3E-13 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 2.3E-13 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 2.3E-13 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 Gene3D G3DSA:3.40.710.10 28 296 1.1E-81 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 Gene3D G3DSA:2.60.410.10 301 399 2.2E-22 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 SMART SM00936 299 399 7.1E-15 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 SUPERFAMILY SSF69189 291 410 3.53E-13 T 21-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 28 275 1.5E-78 T 21-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 PANTHER PTHR21581:SF11 1 414 1.4E-96 T 21-04-2016 HSISS4_RS00500 48f64b049fec8d253876b64ee6b33894 418 PANTHER PTHR21581 1 414 1.4E-96 T 21-04-2016 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 SMART SM01409 9 61 5.2E-13 T 21-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 Pfam PF01192 RNA polymerase Rpb6 9 61 1.0E-11 T 21-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 2 62 14.945 T 21-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 PANTHER PTHR34476 3 91 4.4E-20 T 21-04-2016 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 Gene3D G3DSA:3.90.940.10 2 79 5.7E-25 T 21-04-2016 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 2 59 1.2E-13 T 21-04-2016 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS06940 42292932e0a5ae91498a9f17c02459c3 104 SUPERFAMILY SSF63562 2 72 5.41E-24 T 21-04-2016 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 Pfam PF00977 Histidine biosynthesis protein 5 234 1.3E-87 T 21-04-2016 IPR006062 Histidine biosynthesis GO:0000105 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 251 1.4E-107 T 21-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 PANTHER PTHR21235 1 252 1.2E-121 T 21-04-2016 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 Gene3D G3DSA:3.20.20.70 4 251 8.3E-103 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 SUPERFAMILY SSF51366 1 251 5.97E-84 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 PANTHER PTHR21235:SF2 1 252 1.2E-121 T 21-04-2016 HSISS4_RS03915 9333385bd526d45d88cc25b9795898d6 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 47.887 T 21-04-2016 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 UniPathway: UPA00031 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 457 751 9.2E-53 T 21-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 SUPERFAMILY SSF49899 762 924 2.85E-25 T 21-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 SMART SM00635 933 1012 1.5E-9 T 21-04-2016 IPR003343 Bacterial Ig-like, group 2 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Pfam PF02210 Laminin G domain 1083 1151 4.2E-5 T 21-04-2016 IPR001791 Laminin G domain HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Gene3D G3DSA:2.60.40.1080 943 1016 2.5E-7 T 21-04-2016 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 PANTHER PTHR30175 437 926 3.4E-74 T 21-04-2016 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Pfam PF02368 Bacterial Ig-like domain (group 2) 933 1011 6.4E-13 T 21-04-2016 IPR003343 Bacterial Ig-like, group 2 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Pfam PF06439 Domain of Unknown Function (DUF1080) 164 330 7.7E-8 T 21-04-2016 IPR010496 Domain of unknown function DUF1080 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 PANTHER PTHR30175:SF0 437 926 3.4E-74 T 21-04-2016 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 6 24 1.9E-5 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Gene3D G3DSA:2.60.120.560 758 924 8.1E-28 T 21-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 SUPERFAMILY SSF75005 447 763 1.75E-72 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 SMART SM00640 457 885 5.0E-94 T 21-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Gene3D G3DSA:2.60.120.200 1079 1151 4.3E-5 T 21-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 457 470 - T 21-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 812 883 1.5E-12 T 21-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 Gene3D G3DSA:2.120.10.10 502 703 2.8E-29 T 21-04-2016 IPR011040 Sialidases HSISS4_RS06005 42e32f09d0330e854df0c09e72761d5f 1303 SUPERFAMILY SSF49899 1079 1169 9.04E-8 T 21-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 Pfam PF00534 Glycosyl transferases group 1 196 334 6.3E-28 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 PANTHER PTHR12526:SF363 1 419 2.9E-101 T 21-04-2016 HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 Pfam PF13439 Glycosyltransferase Family 4 15 182 2.0E-33 T 21-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 SUPERFAMILY SSF53756 1 377 3.1E-75 T 21-04-2016 HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 PANTHER PTHR12526 1 419 2.9E-101 T 21-04-2016 HSISS4_RS02665 d97a0c38448bb82c14dfd3e11fd27376 440 Gene3D G3DSA:3.40.50.2000 174 357 1.8E-26 T 21-04-2016 HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 Gene3D G3DSA:3.30.1330.10 20 169 8.1E-63 T 21-04-2016 IPR016188 PurM-like, N-terminal domain HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 PANTHER PTHR10520 7 334 1.6E-192 T 21-04-2016 HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 SUPERFAMILY SSF55326 6 169 4.49E-49 T 21-04-2016 HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 176 339 3.5E-37 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 6 331 3.8E-136 T 21-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 Gene3D G3DSA:3.90.650.10 170 339 6.0E-63 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 SUPERFAMILY SSF56042 170 338 4.64E-55 T 21-04-2016 IPR010918 AIR synthase-related protein, C-terminal domain HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 162 4.4E-17 T 21-04-2016 IPR016188 PurM-like, N-terminal domain HSISS4_RS00230 f919aedfa62af0e1fd5543330336ddc7 340 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 5 340 45.954 T 21-04-2016 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 SMART SM00530 3 58 1.3E-15 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 Pfam PF01381 Helix-turn-helix 4 56 1.4E-18 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 SUPERFAMILY SSF47413 2 60 4.56E-19 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 PANTHER PTHR10245 8 65 6.6E-18 T 21-04-2016 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 Gene3D G3DSA:1.10.260.40 2 61 2.2E-25 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS05925 7ad7fe6dd9533af1ac58169493ff11d5 65 PANTHER PTHR10245:SF56 8 65 6.6E-18 T 21-04-2016 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 PANTHER PTHR30614 13 225 3.1E-52 T 21-04-2016 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 Gene3D G3DSA:1.10.3720.10 16 224 2.3E-37 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 SUPERFAMILY SSF161098 18 215 3.53E-38 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 224 5.1E-15 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 17 113 4.3E-20 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS07610 130d931c10ac7ef59182c764e2d6be3f 225 PANTHER PTHR30614:SF0 13 225 3.1E-52 T 21-04-2016 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 70 122 1.3E-17 T 21-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Pfam PF09285 Elongation factor P, C-terminal 130 185 1.1E-23 T 21-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Gene3D G3DSA:2.40.50.140 66 128 1.5E-21 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 SUPERFAMILY SSF50249 129 186 1.5E-17 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 SUPERFAMILY SSF50249 65 128 3.17E-17 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Gene3D G3DSA:2.30.30.30 1 64 3.3E-20 T 21-04-2016 IPR014722 Ribosomal protein L2 domain 2 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 SMART SM00841 130 185 1.6E-30 T 21-04-2016 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Hamap MF_00141 Elongation factor P [efp]. 1 186 46.937 T 21-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 ProSitePatterns PS01275 Elongation factor P signature. 151 170 - T 21-04-2016 IPR013852 Translation elongation factor P/YeiP, conserved site UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 61 2.5E-20 T 21-04-2016 IPR013185 Translation elongation factor, KOW-like UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 PANTHER PTHR30053 1 186 6.3E-75 T 21-04-2016 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 SUPERFAMILY SSF50104 1 64 5.78E-16 T 21-04-2016 IPR008991 Translation protein SH3-like domain HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 SMART SM01185 68 122 1.9E-20 T 21-04-2016 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 PIRSF PIRSF005901 1 186 3.6E-62 T 21-04-2016 IPR020599 Translation elongation factor P/YeiP UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 TIGRFAM TIGR00038 efp: translation elongation factor P 2 186 1.3E-66 T 21-04-2016 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 UniPathway: UPA00345 HSISS4_RS08380 bd6fc374c93e3afb0314b121a9868970 186 Gene3D G3DSA:2.40.50.140 129 186 1.3E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 PANTHER PTHR22769 19 243 1.8E-24 T 21-04-2016 HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 SUPERFAMILY SSF55811 25 184 1.9E-26 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 PANTHER PTHR22769:SF42 19 243 1.8E-24 T 21-04-2016 HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 Gene3D G3DSA:3.90.79.10 23 176 1.0E-36 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 Pfam PF00293 NUDIX domain 42 152 4.0E-8 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS01955 99cc506b4bee984164225b84d93d7ebc 253 Gene3D G3DSA:1.10.10.10 182 250 1.4E-18 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PANTHER PTHR11655:SF14 1 178 6.6E-86 T 21-04-2016 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 Gene3D G3DSA:3.90.930.12 2 82 1.8E-31 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 37.491 T 21-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 2.3E-74 T 21-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PIRSF PIRSF002162 1 177 9.9E-48 T 21-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 SUPERFAMILY SSF56053 1 82 3.27E-27 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 Pfam PF00347 Ribosomal protein L6 91 164 1.2E-19 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 Pfam PF00347 Ribosomal protein L6 12 82 9.3E-21 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PRINTS PR00059 Ribosomal protein L6 signature 71 96 1.0E-28 T 21-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PRINTS PR00059 Ribosomal protein L6 signature 99 115 1.0E-28 T 21-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PRINTS PR00059 Ribosomal protein L6 signature 141 162 1.0E-28 T 21-04-2016 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 21-04-2016 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 SUPERFAMILY SSF56053 83 177 1.7E-35 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 PANTHER PTHR11655 1 178 6.6E-86 T 21-04-2016 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS09275 55b89c235a3f5de60ec55de3a4cba44a 178 Gene3D G3DSA:3.90.930.12 83 177 8.9E-38 T 21-04-2016 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 8 25 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 136 156 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 201 225 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 241 258 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 58 85 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 176 200 2.0E-42 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 SUPERFAMILY SSF51735 5 181 3.16E-56 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 Gene3D G3DSA:1.10.1040.10 187 329 2.1E-55 T 21-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 5 163 2.3E-53 T 21-04-2016 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 4 325 36.269 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PANTHER PTHR11728 1 338 4.9E-134 T 21-04-2016 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 183 322 2.0E-50 T 21-04-2016 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 PIRSF PIRSF000114 1 335 4.9E-103 T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 191 212 - T 21-04-2016 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|UniPathway: UPA00940 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 SUPERFAMILY SSF48179 182 334 6.46E-53 T 21-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HSISS4_RS08905 1d1968055213baae84da33fbebc3f815 340 Gene3D G3DSA:3.40.50.720 1 186 3.4E-61 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 PANTHER PTHR11098:SF1 9 478 4.3E-205 T 21-04-2016 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 SUPERFAMILY SSF54675 2 135 2.21E-47 T 21-04-2016 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 154 333 1.2E-7 T 21-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 Gene3D G3DSA:3.20.140.10 3 383 9.1E-131 T 21-04-2016 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 PANTHER PTHR11098 9 478 4.3E-205 T 21-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 8 463 3.4E-188 T 21-04-2016 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 SUPERFAMILY SSF51690 137 476 4.56E-129 T 21-04-2016 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: REACT_11193|UniPathway: UPA00253 HSISS4_RS01090 ff2375e93a8ea2f3f9c6325d993b0365 484 PIRSF PIRSF000484 2 478 9.5E-151 T 21-04-2016 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|UniPathway: UPA00253 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Pfam PF02237 Biotin protein ligase C terminal domain 264 309 3.0E-7 T 21-04-2016 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 SUPERFAMILY SSF46785 11 58 6.3E-11 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Gene3D G3DSA:2.30.30.100 264 309 1.1E-10 T 21-04-2016 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 PANTHER PTHR12835 1 309 3.7E-53 T 21-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Pfam PF08279 HTH domain 7 56 1.3E-15 T 21-04-2016 IPR013196 Helix-turn-helix, type 11 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 83 309 1.1E-37 T 21-04-2016 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 SUPERFAMILY SSF55681 68 247 1.09E-45 T 21-04-2016 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Gene3D G3DSA:1.10.10.10 3 61 4.2E-21 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Pfam PF03099 Biotin/lipoate A/B protein ligase family 113 207 2.4E-12 T 21-04-2016 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 6 310 29.014 T 21-04-2016 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 SUPERFAMILY SSF50037 266 309 1.6E-6 T 21-04-2016 IPR008988 Transcriptional repressor, C-terminal HSISS4_RS04255 1688ddfb6fcef12a658c3bf961b1967c 312 Gene3D G3DSA:3.30.930.10 72 245 1.7E-44 T 21-04-2016 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 4.1E-19 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 4.1E-19 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 4.1E-19 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 2.7E-44 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 4.7E-35 T 21-04-2016 IPR027486 Ribosomal protein S10 domain HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 PANTHER PTHR11700 1 102 1.6E-48 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 Gene3D G3DSA:3.30.70.600 3 102 4.1E-43 T 21-04-2016 IPR027486 Ribosomal protein S10 domain HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 26.532 T 21-04-2016 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 SUPERFAMILY SSF54999 5 102 9.81E-37 T 21-04-2016 IPR027486 Ribosomal protein S10 domain HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 SMART SM01403 7 101 2.0E-55 T 21-04-2016 IPR027486 Ribosomal protein S10 domain HSISS4_RS09355 9fd32d83b114afdab0874d227e39e80a 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 21-04-2016 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 PANTHER PTHR11136:SF0 1 420 1.6E-116 T 21-04-2016 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 PANTHER PTHR11136 1 420 1.6E-116 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 Gene3D G3DSA:3.90.190.20 294 416 5.7E-21 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 Gene3D G3DSA:3.40.1190.10 1 292 1.2E-87 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 SUPERFAMILY SSF53244 294 413 6.18E-19 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 412 1.0E-118 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 SUPERFAMILY SSF53623 1 292 1.7E-87 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 Pfam PF08245 Mur ligase middle domain 45 267 1.2E-8 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07390 117d45559be9f936fdab1d38a58319c7 420 PIRSF PIRSF001563 1 419 2.4E-122 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 ProSitePatterns PS00789 Chorismate synthase signature 3. 337 353 - T 21-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 PANTHER PTHR21085:SF0 1 388 1.5E-180 T 21-04-2016 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 TIGRFAM TIGR00033 aroC: chorismate synthase 1 368 1.1E-139 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 PANTHER PTHR21085 1 388 1.5E-180 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 Gene3D G3DSA:3.60.150.10 1 387 3.4E-147 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 Hamap MF_00300 Chorismate synthase [aroC]. 1 370 34.919 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 ProSitePatterns PS00788 Chorismate synthase signature 2. 129 145 - T 21-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 Pfam PF01264 Chorismate synthase 1 363 1.7E-115 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 PIRSF PIRSF001456 1 380 2.7E-122 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 21-04-2016 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03020 295ddb3dc5c0fd12724aa9b9e5be636c 388 SUPERFAMILY SSF103263 1 387 2.75E-146 T 21-04-2016 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 PANTHER PTHR33434:SF1 1 278 8.5E-118 T 21-04-2016 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 Gene3D G3DSA:3.30.1180.10 156 279 1.0E-36 T 21-04-2016 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 SUPERFAMILY SSF82549 1 279 1.18E-80 T 21-04-2016 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 PANTHER PTHR33434 1 278 8.5E-118 T 21-04-2016 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 Gene3D G3DSA:3.40.50.10170 3 151 2.1E-47 T 21-04-2016 HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 277 1.7E-87 T 21-04-2016 IPR003797 DegV HSISS4_RS04085 991c0cd1065db58f15e23d5250359ca8 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 4.5E-85 T 21-04-2016 IPR003797 DegV HSISS4_RS04620 52aada077c22a388d70cf6f3ee6ebc23 213 SUPERFAMILY SSF142795 3 211 2.09E-80 T 21-04-2016 HSISS4_RS04620 52aada077c22a388d70cf6f3ee6ebc23 213 Pfam PF08942 Domain of unknown function (DUF1919) 15 203 7.1E-59 T 21-04-2016 IPR015037 Protein of unknown function DUF1919 HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 PIRSF PIRSF018249 1 276 5.4E-90 T 21-04-2016 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 PANTHER PTHR10108:SF886 32 275 7.0E-46 T 21-04-2016 HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 Gene3D G3DSA:3.40.50.150 69 202 3.5E-20 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 SUPERFAMILY SSF53335 16 248 6.66E-30 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 PANTHER PTHR10108 32 275 7.0E-46 T 21-04-2016 HSISS4_RS08940 40856f6b869156723dac41be53c3b06c 277 Pfam PF13649 Methyltransferase domain 95 164 4.1E-11 T 21-04-2016 HSISS4_RS05615 5e9e86f1240e5611c74ccf2acfbca728 318 PANTHER PTHR32196:SF40 9 318 1.5E-114 T 21-04-2016 HSISS4_RS05615 5e9e86f1240e5611c74ccf2acfbca728 318 PANTHER PTHR32196 9 318 1.5E-114 T 21-04-2016 HSISS4_RS05615 5e9e86f1240e5611c74ccf2acfbca728 318 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 297 1.6E-38 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Pfam PF03144 Elongation factor Tu domain 2 215 285 1.2E-7 T 21-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Hamap MF_00071 Elongation factor 4 [lepA]. 1 608 308.336 T 21-04-2016 IPR006297 Elongation factor 4 GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 184 8.3E-20 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 SMART SM00838 408 496 1.7E-5 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Gene3D G3DSA:3.30.70.870 302 379 9.3E-28 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Gene3D G3DSA:2.40.30.10 204 299 3.1E-24 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 SUPERFAMILY SSF52540 5 211 7.65E-55 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Gene3D G3DSA:3.40.50.300 7 203 1.8E-60 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Pfam PF00009 Elongation factor Tu GTP binding domain 13 191 2.4E-52 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Pfam PF00679 Elongation factor G C-terminus 409 496 1.8E-25 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PANTHER PTHR23115:SF175 1 383 3.5E-291 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PANTHER PTHR23115:SF175 407 606 3.5E-291 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PANTHER PTHR23115 1 383 3.5E-291 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PANTHER PTHR23115 407 606 3.5E-291 T 21-04-2016 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Gene3D G3DSA:3.30.70.240 411 500 7.5E-25 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 SUPERFAMILY SSF54980 302 380 1.12E-19 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 SUPERFAMILY SSF50447 176 298 9.15E-31 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 Pfam PF06421 GTP-binding protein LepA C-terminus 498 604 4.3E-50 T 21-04-2016 IPR013842 GTP-binding protein LepA, C-terminal HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PRINTS PR00315 GTP-binding elongation factor signature 16 29 3.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PRINTS PR00315 GTP-binding elongation factor signature 59 67 3.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 21-04-2016 IPR031157 Tr-type G domain, conserved site HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 SUPERFAMILY SSF54980 409 504 7.19E-27 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS05325 b350811a7fd7f2a84a724108bc5d72d0 610 TIGRFAM TIGR01393 lepA: elongation factor 4 13 606 0.0 T 21-04-2016 IPR006297 Elongation factor 4 GO:0005525 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 Gene3D G3DSA:3.40.50.720 2 149 6.5E-46 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 130 1.1E-16 T 21-04-2016 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 Pfam PF00742 Homoserine dehydrogenase 138 316 2.1E-61 T 21-04-2016 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 SUPERFAMILY SSF55021 349 419 1.63E-5 T 21-04-2016 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 PANTHER PTHR21499 1 370 8.3E-128 T 21-04-2016 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 PIRSF PIRSF000098 1 428 1.7E-163 T 21-04-2016 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 Gene3D G3DSA:3.30.360.10 150 300 7.1E-56 T 21-04-2016 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 SUPERFAMILY SSF55347 138 303 2.35E-52 T 21-04-2016 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 SUPERFAMILY SSF51735 3 159 6.03E-31 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 21-04-2016 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS02190 c6e0ee4a641ba43aa81a61fb75d033b0 428 PANTHER PTHR21499:SF2 1 370 8.3E-128 T 21-04-2016 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 338 35.46 T 21-04-2016 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 21-04-2016 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 SUPERFAMILY SSF52374 5 337 1.44E-79 T 21-04-2016 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 Gene3D G3DSA:1.10.240.10 218 327 4.0E-37 T 21-04-2016 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PANTHER PTHR10055:SF6 3 339 4.6E-184 T 21-04-2016 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 3 337 7.2E-79 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 Gene3D G3DSA:3.40.50.620 3 217 8.5E-77 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PANTHER PTHR10055 3 339 4.6E-184 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 147 168 6.6E-25 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 6.6E-25 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 69 88 6.6E-25 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 6.6E-25 T 21-04-2016 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2|Reactome: REACT_71 HSISS4_RS09700 7ac34fdcbe981034bdfb3cb627062cde 340 Pfam PF00579 tRNA synthetases class I (W and Y) 4 291 4.7E-57 T 21-04-2016 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01365 53e34316fca738c2cc3d1332df2c0f9c 300 Gene3D G3DSA:3.40.190.10 34 169 2.5E-48 T 21-04-2016 HSISS4_RS01365 53e34316fca738c2cc3d1332df2c0f9c 300 PIRSF PIRSF002854 1 286 1.6E-77 T 21-04-2016 IPR004872 Lipoprotein NlpA family HSISS4_RS01365 53e34316fca738c2cc3d1332df2c0f9c 300 Pfam PF03180 NLPA lipoprotein 37 285 3.6E-82 T 21-04-2016 IPR004872 Lipoprotein NlpA family HSISS4_RS01365 53e34316fca738c2cc3d1332df2c0f9c 300 SUPERFAMILY SSF53850 36 289 1.59E-70 T 21-04-2016 HSISS4_RS01365 53e34316fca738c2cc3d1332df2c0f9c 300 PANTHER PTHR30429 2 286 6.8E-82 T 21-04-2016 IPR004872 Lipoprotein NlpA family HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 11 146 4.0E-76 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PANTHER PTHR35799 5 158 7.0E-84 T 21-04-2016 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 Gene3D G3DSA:3.30.1360.80 6 159 1.4E-65 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 8 26 4.3E-34 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 52 70 4.3E-34 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 76 94 4.3E-34 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 31 49 4.3E-34 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 120 139 4.3E-34 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 4 158 35.139 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 PIRSF PIRSF006160 4 160 1.6E-63 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 SUPERFAMILY SSF63411 7 159 1.01E-60 T 21-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HSISS4_RS01845 b0d589473d2ca64a7317a6ab2a3fd418 160 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 7 152 1.0E-53 T 21-04-2016 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 HSISS4_RS04245 4b8b9b1fee4e6eafcad43f579b530bf8 169 Gene3D G3DSA:3.30.450.40 5 155 4.8E-42 T 21-04-2016 IPR029016 GAF domain-like HSISS4_RS04245 4b8b9b1fee4e6eafcad43f579b530bf8 169 PANTHER PTHR21021 9 154 3.7E-39 T 21-04-2016 HSISS4_RS04245 4b8b9b1fee4e6eafcad43f579b530bf8 169 SUPERFAMILY SSF55781 4 155 3.05E-38 T 21-04-2016 IPR029016 GAF domain-like HSISS4_RS04245 4b8b9b1fee4e6eafcad43f579b530bf8 169 Pfam PF13185 GAF domain 51 151 3.6E-12 T 21-04-2016 IPR003018 GAF domain GO:0005515 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 SMART SM00729 21 252 1.3E-32 T 21-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 Pfam PF16199 Radical_SAM C-terminal domain 213 296 5.2E-27 T 21-04-2016 IPR032432 Radical SAM, C-terminal extension HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 PANTHER PTHR11135:SF1 1 303 2.8E-152 T 21-04-2016 IPR005911 Protein YhcC-like GO:0051536 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 Pfam PF04055 Radical SAM superfamily 41 205 1.0E-14 T 21-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 4 305 2.3E-108 T 21-04-2016 IPR005911 Protein YhcC-like GO:0051536 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 PANTHER PTHR11135 1 303 2.8E-152 T 21-04-2016 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 SUPERFAMILY SSF102114 8 302 3.14E-47 T 21-04-2016 HSISS4_RS07970 f9a664b5e24a9d91df29eedc655d0c45 314 Gene3D G3DSA:3.80.30.20 22 253 3.6E-28 T 21-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 Hamap MF_00565 D-alanine--poly(phosphoribitol) ligase subunit 2 [dltC]. 1 77 50.767 T 21-04-2016 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 TIGRFAM TIGR01688 dltC: D-alanine--poly(phosphoribitol) ligase, subunit 2 4 74 4.0E-23 T 21-04-2016 IPR003230 D-alanine--poly(phosphoribitol) ligase subunit 2 GO:0019350|GO:0036370 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 Gene3D G3DSA:1.10.1200.10 1 76 2.7E-24 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 PANTHER PTHR41270:SF1 2 77 5.8E-34 T 21-04-2016 HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 SUPERFAMILY SSF47336 4 78 4.06E-14 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 Pfam PF00550 Phosphopantetheine attachment site 6 71 1.1E-10 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS05730 5405a34bb6f80773349e59c5a4d92d18 79 PANTHER PTHR41270 2 77 5.8E-34 T 21-04-2016 HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 21-04-2016 IPR023187 Transcriptional regulator MarR-type, conserved site HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 Gene3D G3DSA:1.10.10.10 20 147 9.9E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 PANTHER PTHR33164 40 144 8.9E-14 T 21-04-2016 HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 Pfam PF01047 MarR family 37 92 3.4E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 SUPERFAMILY SSF46785 19 144 4.15E-22 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05285 8c1e1fe2c79b25e14c1ae59703b94b9a 149 SMART SM00347 26 128 1.2E-12 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 Pfam PF01479 S4 domain 11 55 3.6E-11 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 SMART SM00363 10 73 3.6E-11 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 PANTHER PTHR11079 1 295 5.3E-135 T 21-04-2016 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 Gene3D G3DSA:3.10.290.10 11 57 2.1E-17 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 SUPERFAMILY SSF55174 10 95 1.68E-14 T 21-04-2016 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 Pfam PF00849 RNA pseudouridylate synthase 82 235 4.2E-36 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 SUPERFAMILY SSF55120 68 294 3.36E-80 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 PANTHER PTHR11079:SF71 1 295 5.3E-135 T 21-04-2016 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 128 142 - T 21-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02445 ae03a623a92f2422d5af07d1fbef0294 296 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 7 294 2.3E-99 T 21-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02690 70b0942173207a594936db5e6701aa94 63 PANTHER PTHR33885 1 63 3.7E-26 T 21-04-2016 HSISS4_RS02690 70b0942173207a594936db5e6701aa94 63 Pfam PF04024 PspC domain 3 60 3.0E-25 T 21-04-2016 IPR007168 Phage shock protein, PspC, N-terminal HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 Pfam PF00673 ribosomal L5P family C-terminus 86 178 2.7E-40 T 21-04-2016 IPR031309 Ribosomal protein L5, C-terminal HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 44.004 T 21-04-2016 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 21-04-2016 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 PANTHER PTHR11994 1 179 9.0E-95 T 21-04-2016 HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 Pfam PF00281 Ribosomal protein L5 25 81 1.2E-26 T 21-04-2016 IPR031310 Ribosomal protein L5, N-terminal HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 Gene3D G3DSA:3.30.1440.10 3 179 4.7E-77 T 21-04-2016 IPR022803 Ribosomal protein L5 domain HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 SUPERFAMILY SSF55282 4 179 1.32E-75 T 21-04-2016 IPR022803 Ribosomal protein L5 domain HSISS4_RS09290 f3aebbda1e82f4f72202628de19d7f8e 180 PIRSF PIRSF002161 1 180 1.8E-66 T 21-04-2016 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08225 1521a7af3c923522dceb6612c5b8e103 436 Gene3D G3DSA:3.30.565.10 305 384 1.1E-4 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS08225 1521a7af3c923522dceb6612c5b8e103 436 SUPERFAMILY SSF55874 305 384 5.72E-5 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 PANTHER PTHR22683:SF41 201 804 9.8E-230 T 21-04-2016 HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 SUPERFAMILY SSF52540 412 706 1.12E-43 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 PANTHER PTHR22683 201 804 9.8E-230 T 21-04-2016 HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 SUPERFAMILY SSF46785 739 803 1.84E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 SMART SM00843 739 804 7.3E-38 T 21-04-2016 IPR018541 FtsK gamma domain HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 Gene3D G3DSA:3.40.50.300 413 700 1.2E-79 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 Pfam PF01580 FtsK/SpoIIIE family 448 634 5.6E-56 T 21-04-2016 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 SMART SM00382 473 655 2.1E-4 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06865 3887ebdba43df1889152b5b0b5f9fac0 804 Pfam PF09397 Ftsk gamma domain 741 802 2.1E-28 T 21-04-2016 IPR018541 FtsK gamma domain HSISS4_RS01795 9e9e84f02e053668c2eb4612fd8c22fb 74 Hamap MF_01217 Acyl carrier protein [acpP]. 2 73 17.892 T 21-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HSISS4_RS01795 9e9e84f02e053668c2eb4612fd8c22fb 74 Gene3D G3DSA:1.10.1200.10 3 72 2.8E-20 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS01795 9e9e84f02e053668c2eb4612fd8c22fb 74 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 32 72 3.0E-15 T 21-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HSISS4_RS01795 9e9e84f02e053668c2eb4612fd8c22fb 74 Pfam PF00550 Phosphopantetheine attachment site 5 69 1.5E-14 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS01795 9e9e84f02e053668c2eb4612fd8c22fb 74 SUPERFAMILY SSF47336 3 72 3.66E-17 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 PIRSF PIRSF005485 1 333 1.4E-74 T 21-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 327 3.3E-81 T 21-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 PANTHER PTHR30363:SF17 1 306 1.1E-66 T 21-04-2016 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 Pfam PF01628 HrcA protein C terminal domain 102 315 2.8E-29 T 21-04-2016 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 322 25.479 T 21-04-2016 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 Gene3D G3DSA:3.30.450.40 176 333 1.6E-10 T 21-04-2016 IPR029016 GAF domain-like HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 SUPERFAMILY SSF55781 70 333 6.08E-28 T 21-04-2016 IPR029016 GAF domain-like HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 SUPERFAMILY SSF46785 2 81 3.91E-22 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 Gene3D G3DSA:1.10.10.10 2 81 2.1E-30 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 PANTHER PTHR30363 1 306 1.1E-66 T 21-04-2016 HSISS4_RS00665 5ff627931d6160ee50c5e6f37dd35c18 344 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 2 55 6.7E-6 T 21-04-2016 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 SMART SM00936 299 396 4.4E-14 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 PANTHER PTHR21581:SF11 1 368 1.4E-104 T 21-04-2016 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 PANTHER PTHR21581 1 368 1.4E-104 T 21-04-2016 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 Gene3D G3DSA:3.40.710.10 26 298 1.6E-85 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 60 71 1.7E-14 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 116 133 1.7E-14 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 143 156 1.7E-14 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 299 394 1.3E-8 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 26 275 3.6E-80 T 21-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 Gene3D G3DSA:2.60.410.10 301 396 3.9E-21 T 21-04-2016 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 SUPERFAMILY SSF56601 1 299 1.01E-68 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00505 30214fba3b38df1a05bd0cfcc0a3f7da 415 SUPERFAMILY SSF69189 291 407 4.32E-14 T 21-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS04525 5f683a0f88b4f66270932f47e379dc1f 61 SUPERFAMILY SSF55331 2 58 6.77E-17 T 21-04-2016 IPR014347 Tautomerase/MIF superfamily HSISS4_RS04525 5f683a0f88b4f66270932f47e379dc1f 61 Gene3D G3DSA:3.30.429.20 1 58 1.5E-21 T 21-04-2016 HSISS4_RS04525 5f683a0f88b4f66270932f47e379dc1f 61 PANTHER PTHR35530 1 57 5.5E-14 T 21-04-2016 HSISS4_RS04525 5f683a0f88b4f66270932f47e379dc1f 61 Pfam PF01361 Tautomerase enzyme 2 60 1.1E-23 T 21-04-2016 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 PANTHER PTHR15892 1 60 3.5E-25 T 21-04-2016 HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.7E-28 T 21-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 Gene3D G3DSA:3.30.1390.20 1 59 6.4E-30 T 21-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 PIRSF PIRSF002211 1 60 2.2E-28 T 21-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.7E-19 T 21-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 21-04-2016 IPR018038 Ribosomal protein L30, conserved site HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 19.17 T 21-04-2016 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09260 d347f705c117e8b392153f3347b2c88c 60 SUPERFAMILY SSF55129 1 59 5.36E-20 T 21-04-2016 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 Pfam PF01728 FtsJ-like methyltransferase 62 244 1.9E-18 T 21-04-2016 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 PIRSF PIRSF005578 1 267 5.4E-97 T 21-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 SMART SM00363 4 71 1.3E-5 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 SUPERFAMILY SSF55174 3 71 1.91E-9 T 21-04-2016 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 PANTHER PTHR32319 1 266 2.1E-125 T 21-04-2016 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 PANTHER PTHR32319:SF0 1 266 2.1E-125 T 21-04-2016 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 5 239 1.2E-77 T 21-04-2016 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 Gene3D G3DSA:3.40.50.150 94 223 4.7E-5 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 Gene3D G3DSA:3.10.290.10 4 93 6.3E-20 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 SUPERFAMILY SSF53335 61 254 6.09E-22 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS04070 7bd06b6e25c595e7421daaa6e9b8ae8c 275 Pfam PF01479 S4 domain 4 52 5.5E-6 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS08865 e55a0893a8b6a762814c2da2397b229b 231 PANTHER PTHR31801 9 231 2.8E-40 T 21-04-2016 HSISS4_RS08865 e55a0893a8b6a762814c2da2397b229b 231 Pfam PF01987 Mitochondrial biogenesis AIM24 9 213 4.0E-49 T 21-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 HSISS4_RS08865 e55a0893a8b6a762814c2da2397b229b 231 SUPERFAMILY SSF51219 1 227 1.57E-64 T 21-04-2016 IPR016031 Tryptophan RNA-binding attenuator protein-like domain HSISS4_RS08865 e55a0893a8b6a762814c2da2397b229b 231 Gene3D G3DSA:3.60.160.10 2 230 1.1E-77 T 21-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 HSISS4_RS08865 e55a0893a8b6a762814c2da2397b229b 231 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 9 230 1.8E-34 T 21-04-2016 IPR002838 Mitochondrial biogenesis protein AIM24 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PANTHER PTHR10457:SF6 1 388 8.0E-122 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Pfam PF10509 Galactokinase galactose-binding signature 8 57 1.4E-22 T 21-04-2016 IPR019539 Galactokinase galactose-binding domain KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00473 Galactokinase signature 26 44 2.8E-29 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00473 Galactokinase signature 91 102 2.8E-29 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00473 Galactokinase signature 112 130 2.8E-29 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00473 Galactokinase signature 269 283 2.8E-29 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 SUPERFAMILY SSF54211 4 203 1.29E-61 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Pfam PF08544 GHMP kinases C terminal 284 366 2.3E-15 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Gene3D G3DSA:3.30.70.890 210 385 1.2E-59 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Pfam PF00288 GHMP kinases N terminal domain 114 181 1.0E-11 T 21-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PANTHER PTHR10457 1 388 8.0E-122 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PIRSF PIRSF000530 1 388 3.1E-123 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 SUPERFAMILY SSF55060 206 386 1.19E-56 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 21-04-2016 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 121 132 - T 21-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00959 Mevalonate kinase family signature 162 181 2.0E-42 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00959 Mevalonate kinase family signature 119 141 2.0E-42 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00959 Mevalonate kinase family signature 333 350 2.0E-42 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 PRINTS PR00959 Mevalonate kinase family signature 24 48 2.0E-42 T 21-04-2016 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Hamap MF_00246 Galactokinase [galK]. 24 386 49.355 T 21-04-2016 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 Gene3D G3DSA:3.30.230.10 4 209 2.8E-73 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS06385 b973632c44d4ddefc3f8842afdde80e0 388 TIGRFAM TIGR00131 gal_kin: galactokinase 5 385 6.4E-122 T 21-04-2016 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527|UniPathway: UPA00214 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Gene3D G3DSA:3.30.300.20 198 289 6.2E-28 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 PANTHER PTHR22648:SF0 1 397 9.3E-138 T 21-04-2016 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SUPERFAMILY SSF69705 1 125 3.92E-36 T 21-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Gene3D G3DSA:3.30.1480.10 1 124 9.3E-40 T 21-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 397 27.228 T 21-04-2016 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Gene3D G3DSA:2.40.50.140 128 197 4.9E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SMART SM00316 133 199 0.0052 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SMART SM00322 315 397 4.6E-5 T 21-04-2016 IPR004087 K Homology domain GO:0003676 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SMART SM00322 229 306 1.1 T 21-04-2016 IPR004087 K Homology domain GO:0003676 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 356 5.5E-112 T 21-04-2016 IPR010213 Transcription termination factor NusA GO:0003723 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SUPERFAMILY SSF50249 132 198 1.62E-15 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SUPERFAMILY SSF54814 292 357 2.09E-16 T 21-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 SUPERFAMILY SSF54814 199 271 9.16E-22 T 21-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Pfam PF13184 NusA-like KH domain 229 310 2.7E-29 T 21-04-2016 IPR025249 KH domain, NusA-like GO:0003723 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 PANTHER PTHR22648 1 397 9.3E-138 T 21-04-2016 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Pfam PF08529 NusA N-terminal domain 4 124 2.0E-31 T 21-04-2016 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 HSISS4_RS01545 52373e8071805770c97f9d57af262162 399 Gene3D G3DSA:3.30.300.20 291 359 7.6E-32 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 Gene3D G3DSA:1.10.10.60 189 243 4.8E-20 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 Gene3D G3DSA:1.10.10.60 244 297 7.5E-20 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 SUPERFAMILY SSF46689 190 241 8.45E-11 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 Pfam PF02311 AraC-like ligand binding domain 32 169 1.8E-23 T 21-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 Gene3D G3DSA:2.60.120.280 21 172 3.5E-16 T 21-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 259 274 1.1E-6 T 21-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 274 290 1.1E-6 T 21-04-2016 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 PANTHER PTHR11019 14 298 8.3E-44 T 21-04-2016 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 Pfam PF12833 Helix-turn-helix domain 214 291 1.6E-21 T 21-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 SMART SM00342 207 290 8.4E-30 T 21-04-2016 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 286 - T 21-04-2016 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 SUPERFAMILY SSF51215 15 171 1.44E-17 T 21-04-2016 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 HSISS4_RS04975 671959ab0d188efba8e4de092e62eb6b 302 SUPERFAMILY SSF46689 244 294 1.97E-13 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1184 0.0 T 21-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 SUPERFAMILY SSF64484 5 1185 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Pfam PF00623 RNA polymerase Rpb1, domain 2 334 474 3.2E-37 T 21-04-2016 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Pfam PF04997 RNA polymerase Rpb1, domain 1 5 332 5.2E-86 T 21-04-2016 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Pfam PF04998 RNA polymerase Rpb1, domain 5 771 1132 2.5E-62 T 21-04-2016 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376 1120 1180 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 5 1193 10.246 T 21-04-2016 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376:SF32 1120 1180 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 SMART SM00663 225 504 9.9E-175 T 21-04-2016 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Gene3D G3DSA:2.40.50.100 973 1029 3.6E-5 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376 2 541 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376 559 1079 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Gene3D G3DSA:2.40.40.20 407 476 9.2E-37 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Gene3D G3DSA:2.40.40.20 339 366 9.2E-37 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Pfam PF05000 RNA polymerase Rpb1, domain 4 706 760 7.2E-13 T 21-04-2016 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376:SF32 2 541 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 PANTHER PTHR19376:SF32 559 1079 0.0 T 21-04-2016 HSISS4_RS09085 9a5c98f848d599e85c91ab3d392849eb 1212 Pfam PF04983 RNA polymerase Rpb1, domain 3 479 664 7.5E-34 T 21-04-2016 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09550 cc03a53bb2a8515dbb2cf60d4e01bf18 202 PANTHER PTHR12992 20 194 4.5E-28 T 21-04-2016 HSISS4_RS09550 cc03a53bb2a8515dbb2cf60d4e01bf18 202 SUPERFAMILY SSF55811 20 191 1.62E-23 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS09550 cc03a53bb2a8515dbb2cf60d4e01bf18 202 Gene3D G3DSA:3.90.79.10 19 199 1.7E-29 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS09550 cc03a53bb2a8515dbb2cf60d4e01bf18 202 ProSitePatterns PS00893 Nudix box signature. 58 79 - T 21-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HSISS4_RS09550 cc03a53bb2a8515dbb2cf60d4e01bf18 202 Pfam PF00293 NUDIX domain 28 105 1.1E-13 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Gene3D G3DSA:3.40.50.970 3 174 3.5E-50 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 535 9.6E-32 T 21-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 SUPERFAMILY SSF52518 365 584 2.14E-52 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 SUPERFAMILY SSF52518 5 173 1.22E-42 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 PANTHER PTHR18968:SF124 1 590 8.3E-302 T 21-04-2016 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 SUPERFAMILY SSF52467 189 357 1.64E-39 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 424 443 - T 21-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 173 2.6E-40 T 21-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 326 1.7E-25 T 21-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 PANTHER PTHR18968 1 590 8.3E-302 T 21-04-2016 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 TIGRFAM TIGR02720 pyruv_oxi_spxB: pyruvate oxidase 8 582 7.8E-302 T 21-04-2016 IPR014092 Pyruvate oxidase GO:0047112|GO:0055114 KEGG: 00620+1.2.3.3 HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Gene3D G3DSA:3.40.50.1220 191 351 9.4E-40 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05130 b9a59002a6dc4d2fa57f79d4f08761bd 591 Gene3D G3DSA:3.40.50.970 358 574 1.8E-48 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 PANTHER PTHR11808:SF12 267 426 1.2E-248 T 21-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 PANTHER PTHR11808:SF12 1 237 1.2E-248 T 21-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 423 2.7E-144 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 Gene3D G3DSA:3.90.1150.10 290 426 1.2E-48 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 SUPERFAMILY SSF53383 6 423 6.38E-131 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 Gene3D G3DSA:3.40.640.10 6 288 4.0E-125 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 PANTHER PTHR11808 267 426 1.2E-248 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 PANTHER PTHR11808 1 237 1.2E-248 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 7 423 1.9E-196 T 21-04-2016 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 KEGG: 00270+2.5.1.49|MetaCyc: PWY-5344|MetaCyc: PWY-7174 HSISS4_RS04955 e1af23f754d6deadebf3f81fd282cdfd 426 PIRSF PIRSF001434 1 426 1.7E-131 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS06165 ecdc8024edf4d6b54ba6e2b9adcc629d 279 PANTHER PTHR32552 5 276 3.4E-77 T 21-04-2016 HSISS4_RS06165 ecdc8024edf4d6b54ba6e2b9adcc629d 279 Pfam PF00665 Integrase core domain 115 230 2.0E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS06165 ecdc8024edf4d6b54ba6e2b9adcc629d 279 Gene3D G3DSA:3.30.420.10 109 270 4.4E-25 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06165 ecdc8024edf4d6b54ba6e2b9adcc629d 279 Pfam PF13276 HTH-like domain 35 91 5.8E-20 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS06165 ecdc8024edf4d6b54ba6e2b9adcc629d 279 SUPERFAMILY SSF53098 110 272 2.58E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 Pfam PF02547 Queuosine biosynthesis protein 4 341 2.7E-139 T 21-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 Gene3D G3DSA:2.40.10.240 64 143 1.1E-30 T 21-04-2016 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 SUPERFAMILY SSF111337 1 341 1.1E-137 T 21-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 Gene3D G3DSA:3.40.1780.10 178 341 1.2E-100 T 21-04-2016 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 Gene3D G3DSA:3.40.1780.10 1 62 1.2E-100 T 21-04-2016 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 PANTHER PTHR30307 2 347 3.0E-178 T 21-04-2016 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 342 46.278 T 21-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 PANTHER PTHR30307:SF0 2 347 3.0E-178 T 21-04-2016 HSISS4_RS02530 2b12b03c77229b958021fa757b0c9e06 347 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 341 1.5E-140 T 21-04-2016 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 PANTHER PTHR10871 1 121 2.5E-70 T 21-04-2016 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 113 1.3E-51 T 21-04-2016 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 Gene3D G3DSA:1.10.8.50 1 71 1.0E-29 T 21-04-2016 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 21-04-2016 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 Pfam PF00416 Ribosomal protein S13/S18 62 108 3.0E-18 T 21-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 PIRSF PIRSF002134 1 121 3.0E-43 T 21-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 Gene3D G3DSA:4.10.910.10 72 121 1.7E-27 T 21-04-2016 IPR027437 30s ribosomal protein S13, C-terminal HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 SUPERFAMILY SSF46946 2 112 1.85E-44 T 21-04-2016 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 HSISS4_RS09235 6bf2e57269758dcea5e6d1cb82f00be5 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.391 T 21-04-2016 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Gene3D G3DSA:3.40.50.970 343 534 5.3E-74 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 SMART SM00861 352 523 4.0E-64 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 PANTHER PTHR11624:SF1 3 315 0.0 T 21-04-2016 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 PANTHER PTHR11624:SF1 339 653 0.0 T 21-04-2016 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 SUPERFAMILY SSF52518 6 326 1.65E-112 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 ProSitePatterns PS00802 Transketolase signature 2. 465 481 - T 21-04-2016 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 SUPERFAMILY SSF52518 345 524 4.35E-65 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Pfam PF02779 Transketolase, pyrimidine binding domain 352 522 7.8E-44 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Gene3D G3DSA:3.40.50.920 537 658 1.6E-42 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Gene3D G3DSA:3.40.50.970 6 327 1.7E-120 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 TIGRFAM TIGR00232 tktlase_bact: transketolase 10 659 6.9E-273 T 21-04-2016 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Pfam PF02780 Transketolase, C-terminal domain 552 652 1.4E-10 T 21-04-2016 IPR033248 Transketolase, C-terminal domain HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 PANTHER PTHR11624 3 315 0.0 T 21-04-2016 IPR033247 Transketolase family HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 PANTHER PTHR11624 339 653 0.0 T 21-04-2016 IPR033247 Transketolase family HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 333 7.3E-147 T 21-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 SUPERFAMILY SSF52922 533 660 1.83E-37 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS02295 9ba76b21ee1a284498a5b687004e6048 661 ProSitePatterns PS00801 Transketolase signature 1. 15 35 - T 21-04-2016 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560|UniPathway: UPA00064 HSISS4_RS07330 3151fa4d5137cb67cd55e579932701ce 299 SMART SM00244 21 181 9.7E-28 T 21-04-2016 IPR001107 Band 7 domain HSISS4_RS07330 3151fa4d5137cb67cd55e579932701ce 299 PANTHER PTHR10264:SF84 5 298 1.9E-146 T 21-04-2016 HSISS4_RS07330 3151fa4d5137cb67cd55e579932701ce 299 SUPERFAMILY SSF117892 57 187 9.42E-25 T 21-04-2016 IPR001107 Band 7 domain HSISS4_RS07330 3151fa4d5137cb67cd55e579932701ce 299 PANTHER PTHR10264 5 298 1.9E-146 T 21-04-2016 IPR001972 Stomatin family GO:0016020 HSISS4_RS07330 3151fa4d5137cb67cd55e579932701ce 299 Pfam PF01145 SPFH domain / Band 7 family 25 197 3.8E-27 T 21-04-2016 IPR001107 Band 7 domain HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 Gene3D G3DSA:3.90.400.10 102 163 4.5E-25 T 21-04-2016 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 Gene3D G3DSA:3.20.20.80 6 101 3.9E-111 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 Gene3D G3DSA:3.20.20.80 167 465 3.9E-111 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 PANTHER PTHR10357:SF170 442 536 2.6E-284 T 21-04-2016 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 PANTHER PTHR10357:SF170 5 412 2.6E-284 T 21-04-2016 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 5 538 5.1E-256 T 21-04-2016 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 Pfam PF00128 Alpha amylase, catalytic domain 26 365 1.1E-101 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 Gene3D G3DSA:2.60.40.1180 468 540 4.8E-18 T 21-04-2016 IPR013780 Glycosyl hydrolase, all-beta HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 SMART SM00642 11 407 3.7E-123 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 SUPERFAMILY SSF51011 466 539 2.97E-15 T 21-04-2016 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 PANTHER PTHR10357 442 536 2.6E-284 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 PANTHER PTHR10357 5 412 2.6E-284 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS09165 3c5cd07c24080a50c48b62224a9f0bba 541 SUPERFAMILY SSF51445 6 463 2.25E-135 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 Pfam PF00696 Amino acid kinase family 5 234 2.8E-40 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 SUPERFAMILY SSF53633 4 243 3.8E-54 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 PIRSF PIRSF000728 1 245 9.9E-69 T 21-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 PRINTS PR00474 Glutamate 5-kinase family signature 127 148 5.7E-8 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 5.7E-8 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 PRINTS PR00474 Glutamate 5-kinase family signature 159 186 5.7E-8 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 Gene3D G3DSA:3.40.1160.10 4 244 5.2E-65 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 Hamap MF_00082_B Acetylglutamate kinase [argB]. 2 245 24.843 T 21-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 TIGRFAM TIGR00761 argB: acetylglutamate kinase 6 233 1.5E-64 T 21-04-2016 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02175 fe38245227f88c21db0dbc32775c7887 245 PANTHER PTHR23342 6 245 2.6E-50 T 21-04-2016 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 SUPERFAMILY SSF52172 1 127 8.82E-11 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 SMART SM00448 1 122 4.1E-6 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 PANTHER PTHR26402 1 222 1.9E-34 T 21-04-2016 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 Pfam PF00072 Response regulator receiver domain 3 122 1.4E-11 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 Pfam PF04397 LytTr DNA-binding domain 151 241 1.1E-22 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 Gene3D G3DSA:2.40.50.40 140 207 4.5E-12 T 21-04-2016 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 SMART SM00850 148 242 5.7E-18 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 PANTHER PTHR26402:SF577 1 222 1.9E-34 T 21-04-2016 HSISS4_RS08810 2ee290d4c9d38b91b71325b06eefdbbf 247 Gene3D G3DSA:3.40.50.2300 1 127 1.2E-14 T 21-04-2016 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 122 1.9E-50 T 21-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 SUPERFAMILY SSF53271 71 308 2.44E-62 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 SMART SM01400 6 122 9.0E-79 T 21-04-2016 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 Gene3D G3DSA:3.40.50.2020 3 161 1.6E-75 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 Gene3D G3DSA:3.40.50.2020 162 289 2.4E-51 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 130 145 - T 21-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 PANTHER PTHR10210:SF41 1 321 1.2E-184 T 21-04-2016 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 6 317 50.172 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 Pfam PF14572 Phosphoribosyl synthetase-associated domain 208 316 6.9E-23 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 317 9.1E-123 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS00190 6636e017c04789b74ba5062126f3a452 321 PANTHER PTHR10210 1 321 1.2E-184 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Pfam PF01473 Putative cell wall binding repeat 343 360 0.0012 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Pfam PF01473 Putative cell wall binding repeat 456 474 4.3E-4 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Pfam PF01473 Putative cell wall binding repeat 629 648 0.25 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Pfam PF01473 Putative cell wall binding repeat 366 378 0.87 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Pfam PF01473 Putative cell wall binding repeat 248 265 0.036 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 539 620 3.4E-11 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 625 710 1.3E-12 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 546 608 9.3E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 761 825 6.3E-14 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 351 413 6.2E-26 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 639 695 1.2E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 SUPERFAMILY SSF69360 634 818 2.55E-25 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 SUPERFAMILY SSF69360 344 409 3.38E-28 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 SUPERFAMILY SSF69360 442 493 3.38E-28 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 346 391 1.1E-17 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 168 209 1.0E-4 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 210 261 2.9E-15 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 711 766 4.2E-9 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 444 519 4.9E-11 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 767 838 3.8E-11 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 Gene3D G3DSA:2.10.270.10 262 314 1.6E-8 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 SUPERFAMILY SSF69360 536 630 4.19E-11 T 21-04-2016 HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 2.5E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06560 5918534f415598f42faaefc1be224693 843 SUPERFAMILY SSF69360 197 335 7.69E-22 T 21-04-2016 HSISS4_RS04190 6de50df4048124966a8e4e34c594202b 260 SUPERFAMILY SSF53474 4 249 2.1E-48 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS04190 6de50df4048124966a8e4e34c594202b 260 Pfam PF00756 Putative esterase 12 246 2.3E-19 T 21-04-2016 IPR000801 Putative esterase HSISS4_RS04190 6de50df4048124966a8e4e34c594202b 260 PANTHER PTHR10907 5 210 3.8E-35 T 21-04-2016 HSISS4_RS04190 6de50df4048124966a8e4e34c594202b 260 Gene3D G3DSA:3.40.50.1820 5 249 1.4E-55 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS04190 6de50df4048124966a8e4e34c594202b 260 PANTHER PTHR10907:SF33 5 210 3.8E-35 T 21-04-2016 HSISS4_RS05210 b9f3402ca42413f00179f802dffef898 120 Pfam PF04973 Nicotinamide mononucleotide transporter 6 115 3.9E-20 T 21-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 HSISS4_RS05210 b9f3402ca42413f00179f802dffef898 120 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 2 119 2.8E-35 T 21-04-2016 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 HSISS4_RS05210 b9f3402ca42413f00179f802dffef898 120 PANTHER PTHR36122 1 119 6.2E-49 T 21-04-2016 HSISS4_RS05210 b9f3402ca42413f00179f802dffef898 120 PANTHER PTHR36122:SF2 1 119 6.2E-49 T 21-04-2016 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Gene3D G3DSA:3.40.50.300 27 82 3.0E-4 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 37 1152 28.685 T 21-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF143517 1002 1159 2.48E-32 T 21-04-2016 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF52540 535 793 1.08E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Pfam PF03461 TRCF domain 1015 1101 7.6E-25 T 21-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Pfam PF00271 Helicase conserved C-terminal domain 816 919 5.5E-16 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SMART SM01058 489 586 6.8E-44 T 21-04-2016 IPR003711 CarD-like/TRCF domain HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Pfam PF02559 CarD-like/TRCF domain 490 585 1.2E-27 T 21-04-2016 IPR003711 CarD-like/TRCF domain HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Pfam PF00270 DEAD/DEAH box helicase 615 774 9.4E-19 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SMART SM00490 836 920 4.2E-17 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Gene3D G3DSA:3.30.2060.10 142 220 1.7E-16 T 21-04-2016 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 PANTHER PTHR14025 399 1149 0.0 T 21-04-2016 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SMART SM00487 610 800 8.1E-35 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF52540 369 478 2.38E-22 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF141259 480 558 1.28E-23 T 21-04-2016 IPR003711 CarD-like/TRCF domain HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 PANTHER PTHR14025:SF21 399 1149 0.0 T 21-04-2016 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1078 0.0 T 21-04-2016 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Gene3D G3DSA:3.40.50.300 599 796 3.9E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 Gene3D G3DSA:3.40.50.300 811 966 7.9E-35 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF52540 793 999 6.02E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SUPERFAMILY SSF52540 26 361 7.73E-81 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00030 e55831cb03b26599d066b5006ceb1055 1168 SMART SM00982 1014 1114 4.7E-34 T 21-04-2016 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Gene3D G3DSA:3.40.50.10490 444 602 1.2E-55 T 21-04-2016 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 38.311 T 21-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Pfam PF13522 Glutamine amidotransferase domain 61 188 3.7E-22 T 21-04-2016 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Pfam PF01380 SIS domain 461 583 3.8E-16 T 21-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Pfam PF01380 SIS domain 289 413 1.3E-28 T 21-04-2016 IPR001347 Sugar isomerase (SIS) GO:0005975|GO:0030246 Reactome: REACT_17015 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Gene3D G3DSA:3.40.50.10490 242 443 8.7E-55 T 21-04-2016 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 SUPERFAMILY SSF53697 245 602 2.69E-92 T 21-04-2016 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 PANTHER PTHR10937 1 602 1.4E-278 T 21-04-2016 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 Gene3D G3DSA:3.60.20.10 2 238 4.9E-69 T 21-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 PANTHER PTHR10937:SF0 1 602 1.4E-278 T 21-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 7.1E-214 T 21-04-2016 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: REACT_17015 HSISS4_RS05485 30998746b18f5ae430266b4d63140385 602 SUPERFAMILY SSF56235 2 232 4.55E-64 T 21-04-2016 IPR029055 Nucleophile aminohydrolases, N-terminal HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 286 27.939 T 21-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 PANTHER PTHR11088 1 284 2.6E-101 T 21-04-2016 HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 SUPERFAMILY SSF52540 5 123 1.9E-18 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 SUPERFAMILY SSF52540 3 41 3.85E-5 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 SUPERFAMILY SSF52540 107 221 3.85E-5 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 Gene3D G3DSA:1.10.287.890 188 267 1.2E-30 T 21-04-2016 HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 Gene3D G3DSA:3.40.50.300 2 166 4.2E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 274 1.2E-75 T 21-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HSISS4_RS04240 6031ecd7a6457027450ca369671a2a19 303 Pfam PF01715 IPP transferase 38 269 1.3E-70 T 21-04-2016 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781 HSISS4_RS07500 cae543a028e902016b08250ad8838e38 181 Pfam PF13302 Acetyltransferase (GNAT) domain 17 153 1.6E-26 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS07500 cae543a028e902016b08250ad8838e38 181 PANTHER PTHR13256 1 174 1.1E-60 T 21-04-2016 HSISS4_RS07500 cae543a028e902016b08250ad8838e38 181 Gene3D G3DSA:3.40.630.30 13 175 1.3E-37 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS07500 cae543a028e902016b08250ad8838e38 181 SUPERFAMILY SSF55729 12 175 5.93E-37 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS07500 cae543a028e902016b08250ad8838e38 181 PANTHER PTHR13256:SF31 1 174 1.1E-60 T 21-04-2016 HSISS4_RS05600 a230e5d6b347cfba82c191d63ceb5d80 160 SUPERFAMILY SSF54403 104 157 2.04E-8 T 21-04-2016 HSISS4_RS05600 a230e5d6b347cfba82c191d63ceb5d80 160 Gene3D G3DSA:3.10.450.40 104 156 9.7E-10 T 21-04-2016 HSISS4_RS05600 a230e5d6b347cfba82c191d63ceb5d80 160 SUPERFAMILY SSF54403 41 104 6.29E-16 T 21-04-2016 HSISS4_RS05600 a230e5d6b347cfba82c191d63ceb5d80 160 Gene3D G3DSA:3.10.450.40 35 103 7.3E-17 T 21-04-2016 HSISS4_RS03760 523b6e21018724888873a9ca31864d11 851 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 101 293 2.1E-12 T 21-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HSISS4_RS03760 523b6e21018724888873a9ca31864d11 851 PANTHER PTHR34697 2 835 6.9E-179 T 21-04-2016 HSISS4_RS03760 523b6e21018724888873a9ca31864d11 851 SUPERFAMILY SSF55729 636 821 1.06E-15 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS03760 523b6e21018724888873a9ca31864d11 851 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 523 819 4.0E-86 T 21-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HSISS4_RS03760 523b6e21018724888873a9ca31864d11 851 PANTHER PTHR34697:SF2 2 835 6.9E-179 T 21-04-2016 HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 SUPERFAMILY SSF75217 90 247 3.2E-48 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 Gene3D G3DSA:3.30.1330.30 5 80 8.9E-23 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 SUPERFAMILY SSF55315 6 81 5.3E-18 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 11 84 3.5E-15 T 21-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 Gene3D G3DSA:3.40.1280.10 94 246 2.3E-52 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 Pfam PF00588 SpoU rRNA Methylase family 101 240 9.1E-42 T 21-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 SMART SM00967 11 85 1.6E-15 T 21-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 PANTHER PTHR12029 2 247 1.2E-81 T 21-04-2016 HSISS4_RS00540 2267f7d7c5dc614996b100457b25089b 247 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 10 246 1.1E-77 T 21-04-2016 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 PANTHER PTHR30519 1 749 0.0 T 21-04-2016 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 SUPERFAMILY SSF51726 385 746 1.7E-106 T 21-04-2016 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 1 748 33.797 T 21-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 6 747 0.0 T 21-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 Gene3D G3DSA:3.20.20.210 1 379 1.8E-129 T 21-04-2016 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 3 311 5.0E-115 T 21-04-2016 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 420 743 1.2E-133 T 21-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 Gene3D G3DSA:3.20.20.210 383 749 5.8E-122 T 21-04-2016 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 PIRSF PIRSF000382 1 749 8.9E-302 T 21-04-2016 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 SUPERFAMILY SSF51726 1 377 4.84E-94 T 21-04-2016 HSISS4_RS05705 ed98dbcb875520ed4c6a3470b87aaf90 749 PANTHER PTHR30519:SF0 1 749 0.0 T 21-04-2016 HSISS4_RS03860 ba6e95087a8c3118b0d8f6ed81e87dba 214 TIGRFAM TIGR01906 integ_TIGR01906: integral membrane protein TIGR01906 1 205 2.1E-47 T 21-04-2016 IPR010178 Integral membrane protein 1906 HSISS4_RS03860 ba6e95087a8c3118b0d8f6ed81e87dba 214 Pfam PF07314 Protein of unknown function (DUF1461) 7 180 1.7E-43 T 21-04-2016 IPR010178 Integral membrane protein 1906 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Gene3D G3DSA:3.30.300.30 406 512 7.5E-23 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 SUPERFAMILY SSF56801 9 512 5.1E-110 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Gene3D G3DSA:2.30.38.10 326 399 4.8E-19 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 503 8.2E-6 T 21-04-2016 IPR025110 AMP-binding enzyme C-terminal domain HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 TIGRFAM TIGR01734 D-ala-DACP-lig: D-alanine--poly(phosphoribitol) ligase, subunit 1 8 514 4.2E-238 T 21-04-2016 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 34 435 9.1E-105 T 21-04-2016 IPR010071 Amino acid adenylation domain HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Gene3D G3DSA:3.40.50.980 160 317 1.1E-36 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Gene3D G3DSA:3.40.50.980 7 159 1.5E-29 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 PANTHER PTHR24095 8 503 9.5E-156 T 21-04-2016 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 21-04-2016 IPR020845 AMP-binding, conserved site HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Hamap MF_00593 D-alanine--poly(phosphoribitol) ligase subunit 1 [dltA]. 1 515 282.88 T 21-04-2016 IPR010072 D-alanine--poly(phosphoribitol) ligase subunit 1 GO:0005524|GO:0047473|GO:0070395 KEGG: 00473+6.1.1.13|UniPathway: UPA00556 HSISS4_RS05740 5d7a55cf2b60650538b97f81d7833cb7 516 Pfam PF00501 AMP-binding enzyme 14 411 1.1E-79 T 21-04-2016 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SUPERFAMILY SSF46600 617 661 2.48E-10 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SUPERFAMILY SSF52540 8 419 1.03E-139 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Hamap MF_00204 UvrABC system protein B [uvrB]. 8 662 43.707 T 21-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:3.40.50.300 423 590 5.7E-41 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 660 0.0 T 21-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:3.30.2060.10 164 240 1.6E-12 T 21-04-2016 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SMART SM00487 14 430 8.0E-27 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Pfam PF04851 Type III restriction enzyme, res subunit 17 143 1.2E-13 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Pfam PF00271 Helicase conserved C-terminal domain 439 549 2.0E-19 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:4.10.860.10 607 662 4.8E-15 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:3.40.50.300 283 343 3.1E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:3.40.50.300 393 414 3.1E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Gene3D G3DSA:3.40.50.300 11 94 3.1E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Pfam PF12344 Ultra-violet resistance protein B 556 598 8.9E-25 T 21-04-2016 IPR024759 UvrB, YAD/RRR-motif-containing domain HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 Pfam PF02151 UvrB/uvrC motif 628 660 3.4E-9 T 21-04-2016 IPR001943 UVR domain GO:0005515 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 PANTHER PTHR24029 4 662 0.0 T 21-04-2016 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SMART SM00490 464 550 3.0E-20 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SUPERFAMILY SSF52540 38 72 1.69E-35 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07190 3beb497f7e892bb2d506b29f221f0089 663 SUPERFAMILY SSF52540 461 591 1.69E-35 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PANTHER PTHR22642:SF7 33 300 1.3E-212 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PANTHER PTHR22642:SF7 324 505 1.3E-212 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Gene3D G3DSA:3.20.20.140 492 570 9.9E-184 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Gene3D G3DSA:3.20.20.140 138 433 9.9E-184 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 572 6.1E-295 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PANTHER PTHR22642 33 300 1.3E-212 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PANTHER PTHR22642 324 505 1.3E-212 T 21-04-2016 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Hamap MF_01953 Urease subunit alpha [ureC]. 3 572 55.461 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 ProSitePatterns PS01120 Urease nickel ligands signature. 131 144 - T 21-04-2016 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 SUPERFAMILY SSF51338 4 133 1.53E-55 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 SUPERFAMILY SSF51338 426 477 1.53E-55 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 299 316 3.3E-29 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 431 444 3.3E-29 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 405 420 3.3E-29 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 338 354 3.3E-29 T 21-04-2016 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Pfam PF01979 Amidohydrolase family 129 456 1.7E-64 T 21-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Gene3D G3DSA:2.30.40.10 71 137 1.5E-13 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 SUPERFAMILY SSF51556 485 572 9.72E-183 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 SUPERFAMILY SSF51556 133 436 9.72E-183 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 Pfam PF00449 Urease alpha-subunit, N-terminal domain 4 123 3.4E-51 T 21-04-2016 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01320 3267a6e3832bda30c25baca043c4f147 572 ProSitePatterns PS00145 Urease active site. 321 337 - T 21-04-2016 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Pfam PF11799 impB/mucB/samB family C-terminal domain 295 404 3.9E-15 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 SUPERFAMILY SSF100879 303 398 2.16E-7 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 PANTHER PTHR11076 111 434 4.8E-97 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 PANTHER PTHR11076 13 81 4.8E-97 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Pfam PF00817 impB/mucB/samB family 17 207 2.9E-14 T 21-04-2016 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Pfam PF11798 IMS family HHH motif 223 255 1.2E-6 T 21-04-2016 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 PANTHER PTHR11076:SF31 111 434 4.8E-97 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 PANTHER PTHR11076:SF31 13 81 4.8E-97 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Gene3D G3DSA:3.30.70.270 112 210 2.7E-14 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Gene3D G3DSA:3.30.1490.100 305 405 4.2E-7 T 21-04-2016 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 SUPERFAMILY SSF56672 4 83 1.6E-49 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 SUPERFAMILY SSF56672 116 292 1.6E-49 T 21-04-2016 HSISS4_RS05460 88fca01b68789e68fac02257cc58abe0 471 Gene3D G3DSA:1.10.150.20 221 293 1.4E-24 T 21-04-2016 HSISS4_RS04590 b418dcebb39250efc99a81e68f4416c8 243 PIRSF PIRSF016557 1 243 1.4E-78 T 21-04-2016 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 UniPathway: UPA00934 HSISS4_RS04590 b418dcebb39250efc99a81e68f4416c8 243 PANTHER PTHR39181 2 243 7.0E-40 T 21-04-2016 HSISS4_RS04590 b418dcebb39250efc99a81e68f4416c8 243 SUPERFAMILY SSF51556 1 238 1.22E-21 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS04590 b418dcebb39250efc99a81e68f4416c8 243 PANTHER PTHR39181:SF1 2 243 7.0E-40 T 21-04-2016 HSISS4_RS04590 b418dcebb39250efc99a81e68f4416c8 243 Gene3D G3DSA:3.20.20.140 2 218 1.4E-10 T 21-04-2016 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 SUPERFAMILY SSF55811 4 146 1.49E-28 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 4 22 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 101 121 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 138 158 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 121 138 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 68 94 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PRINTS PR01402 Mutator MutX protein signature 22 37 6.2E-60 T 21-04-2016 IPR003562 Mutator MutX protein GO:0006281|GO:0008413 MetaCyc: PWY-6502 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 Pfam PF00293 NUDIX domain 3 130 5.6E-23 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PANTHER PTHR22769:SF39 3 147 5.9E-48 T 21-04-2016 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 21-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 Gene3D G3DSA:3.90.79.10 3 159 9.0E-40 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS04455 a46331c33e28b70f788b684d07ccd55a 160 PANTHER PTHR22769 3 147 5.9E-48 T 21-04-2016 HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 SUPERFAMILY SSF52540 34 242 4.22E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 PANTHER PTHR24220:SF117 34 256 9.7E-96 T 21-04-2016 HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 Pfam PF00005 ABC transporter 47 178 4.8E-21 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 Gene3D G3DSA:3.40.50.300 4 245 1.6E-50 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 SMART SM00382 56 254 2.4E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07075 65b59b0560e1236909a7235457029604 401 PANTHER PTHR24220 34 256 9.7E-96 T 21-04-2016 HSISS4_RS09365 14c8788d1da720ff7ce59081e64fd3c0 607 SUPERFAMILY SSF52266 424 574 3.75E-6 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS09365 14c8788d1da720ff7ce59081e64fd3c0 607 PANTHER PTHR23028 2 411 8.3E-57 T 21-04-2016 HSISS4_RS09365 14c8788d1da720ff7ce59081e64fd3c0 607 PANTHER PTHR23028:SF53 2 411 8.3E-57 T 21-04-2016 HSISS4_RS09365 14c8788d1da720ff7ce59081e64fd3c0 607 Pfam PF01757 Acyltransferase family 4 341 6.0E-22 T 21-04-2016 IPR002656 Acyltransferase 3 GO:0016747 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 211 1.2E-91 T 21-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 SMART SM01133 2 213 5.2E-104 T 21-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 215 38.199 T 21-04-2016 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 Gene3D G3DSA:3.20.20.70 3 216 1.3E-94 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 Pfam PF01791 DeoC/LacD family aldolase 6 212 3.6E-21 T 21-04-2016 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 PANTHER PTHR10889 3 218 9.0E-115 T 21-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 SUPERFAMILY SSF51569 3 214 3.24E-86 T 21-04-2016 HSISS4_RS05640 670e9a4bba8c00115f43a02b018774a7 220 PIRSF PIRSF001357 2 219 4.7E-80 T 21-04-2016 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|UniPathway: UPA00002 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 PANTHER PTHR24221 2 590 6.3E-271 T 21-04-2016 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 Pfam PF00005 ABC transporter 371 516 7.4E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 Pfam PF00664 ABC transporter transmembrane region 25 306 8.8E-50 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 SUPERFAMILY SSF90123 3 334 5.89E-76 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 Gene3D G3DSA:1.20.1560.10 11 333 8.6E-74 T 21-04-2016 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 SMART SM00382 377 562 3.4E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 PANTHER PTHR24221:SF271 2 590 6.3E-271 T 21-04-2016 HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 Gene3D G3DSA:3.40.50.300 352 579 2.2E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01990 0edb04dce344bf80f1052bc93f1678c9 592 SUPERFAMILY SSF52540 343 587 2.11E-87 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02875 59264bbeb529f6e62bc5680591e54014 258 PANTHER PTHR10992 7 253 1.3E-19 T 21-04-2016 HSISS4_RS02875 59264bbeb529f6e62bc5680591e54014 258 SUPERFAMILY SSF53474 7 233 2.38E-34 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS02875 59264bbeb529f6e62bc5680591e54014 258 Pfam PF12697 Alpha/beta hydrolase family 7 234 5.3E-17 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS02875 59264bbeb529f6e62bc5680591e54014 258 Gene3D G3DSA:3.40.50.1820 7 251 6.0E-35 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS01345 a7c9f7dd1bfba928939c32c990aa0d6c 325 Pfam PF13190 PDGLE domain 233 319 1.4E-9 T 21-04-2016 IPR025937 PDGLE domain HSISS4_RS01345 a7c9f7dd1bfba928939c32c990aa0d6c 325 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 213 1.6E-61 T 21-04-2016 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 UniPathway: UPA00148 HSISS4_RS01345 a7c9f7dd1bfba928939c32c990aa0d6c 325 PANTHER PTHR34229:SF1 2 322 7.4E-74 T 21-04-2016 HSISS4_RS01345 a7c9f7dd1bfba928939c32c990aa0d6c 325 ProDom PD074023 BIOSYNTHESIS COBALAMIN CBIM COBALT PRECURSOR SIGNAL NICKEL MEMBRANE ABC PROTEIN 251 325 2.0E-37 T 21-04-2016 IPR020486 Uncharacterised protein family MJ1570 HSISS4_RS01345 a7c9f7dd1bfba928939c32c990aa0d6c 325 PANTHER PTHR34229 2 322 7.4E-74 T 21-04-2016 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PANTHER PTHR33154 8 119 5.8E-28 T 21-04-2016 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 63 6.0E-16 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 80 95 6.0E-16 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 6.0E-16 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 6.0E-16 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 SUPERFAMILY SSF46785 19 111 1.31E-26 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 PANTHER PTHR33154:SF9 8 119 5.8E-28 T 21-04-2016 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 Pfam PF01022 Bacterial regulatory protein, arsR family 38 83 2.0E-15 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 Gene3D G3DSA:1.10.10.10 15 116 1.2E-32 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 SMART SM00418 31 109 8.7E-28 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS03125 df274e01a39e02d5f9641f833425c498 120 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 54 72 - T 21-04-2016 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 Pfam PF00912 Transglycosylase 132 301 1.6E-51 T 21-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 Gene3D G3DSA:1.10.3810.10 138 333 5.8E-56 T 21-04-2016 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 PANTHER PTHR32282:SF5 53 766 2.1E-167 T 21-04-2016 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 SUPERFAMILY SSF53955 119 341 3.37E-55 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 Pfam PF00905 Penicillin binding protein transpeptidase domain 442 676 6.3E-22 T 21-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 Gene3D G3DSA:3.40.710.10 382 759 2.8E-84 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 PANTHER PTHR32282 53 766 2.1E-167 T 21-04-2016 HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 SUPERFAMILY SSF56601 376 792 1.31E-90 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS09095 63f64c76ecba9539ebc5a8390821c8f8 807 SUPERFAMILY SSF56601 304 322 1.31E-90 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 Hamap MF_00163 Peptide deformylase [def]. 15 203 24.979 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PANTHER PTHR10458:SF8 1 204 1.1E-91 T 21-04-2016 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 Pfam PF01327 Polypeptide deformylase 16 192 2.3E-42 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PANTHER PTHR10458 1 204 1.1E-91 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 SUPERFAMILY SSF56420 6 201 1.96E-57 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 17 197 1.8E-36 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PIRSF PIRSF004749 2 204 3.6E-41 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PRINTS PR01576 Peptide deformylase signature 142 160 1.2E-28 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PRINTS PR01576 Peptide deformylase signature 59 88 1.2E-28 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PRINTS PR01576 Peptide deformylase signature 129 140 1.2E-28 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 PRINTS PR01576 Peptide deformylase signature 161 190 1.2E-28 T 21-04-2016 IPR000181 Formylmethionine deformylase GO:0005506|GO:0042586 HSISS4_RS00800 ce89dfc033265e845b6c728e4e2eea72 204 Gene3D G3DSA:3.90.45.10 16 200 2.0E-51 T 21-04-2016 IPR023635 Peptide deformylase HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PANTHER PTHR11649:SF37 1 143 4.6E-236 T 21-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PANTHER PTHR11649:SF37 261 673 4.6E-236 T 21-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 634 2.5E-163 T 21-04-2016 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PANTHER PTHR11649 1 143 4.6E-236 T 21-04-2016 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PANTHER PTHR11649 261 673 4.6E-236 T 21-04-2016 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 Pfam PF02421 Ferrous iron transport protein B 3 155 1.1E-65 T 21-04-2016 IPR011619 Ferrous iron transport protein B, N-terminal GO:0005525|GO:0015093|GO:0015684|GO:0016021 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.4E-5 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.4E-5 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 SUPERFAMILY SSF52540 3 169 1.56E-37 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 Gene3D G3DSA:3.40.50.300 3 163 3.8E-33 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 Pfam PF07670 Nucleoside recognition 513 636 1.3E-28 T 21-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 Pfam PF07670 Nucleoside recognition 352 446 9.8E-13 T 21-04-2016 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: REACT_15518|Reactome: REACT_1698 HSISS4_RS02870 d26a5f96c2e239af38327252d5e21c3a 712 Pfam PF07664 Ferrous iron transport protein B C terminus 456 506 1.9E-15 T 21-04-2016 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 HSISS4_RS07340 7c96b054c599d55fc7a75599316ff196 258 SUPERFAMILY SSF161098 4 248 6.67E-48 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07340 7c96b054c599d55fc7a75599316ff196 258 Gene3D G3DSA:1.10.3720.10 2 256 1.2E-53 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07340 7c96b054c599d55fc7a75599316ff196 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 248 1.3E-16 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07340 7c96b054c599d55fc7a75599316ff196 258 PANTHER PTHR30222:SF1 8 256 1.6E-70 T 21-04-2016 HSISS4_RS07340 7c96b054c599d55fc7a75599316ff196 258 PANTHER PTHR30222 8 256 1.6E-70 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 236 6.0E-29 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 PANTHER PTHR10000 3 269 5.3E-61 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 Gene3D G3DSA:3.40.50.1000 183 268 1.2E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 Gene3D G3DSA:3.40.50.1000 1 75 1.2E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 8 22 3.1E-5 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 240 252 3.1E-5 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 217 236 3.1E-5 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 SUPERFAMILY SSF56784 1 267 4.78E-66 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 263 5.2E-66 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 Gene3D G3DSA:3.30.1240.10 85 182 4.3E-16 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 PANTHER PTHR10000:SF8 3 269 5.3E-61 T 21-04-2016 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 263 1.3E-55 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS01030 7f60c90f420a6e3af750b335b688908b 269 ProSitePatterns PS01229 Hypothetical cof family signature 2. 217 239 - T 21-04-2016 HSISS4_RS05820 75e6b872612dbf14ce145beb06042573 314 SUPERFAMILY SSF64182 14 306 7.46E-74 T 21-04-2016 HSISS4_RS05820 75e6b872612dbf14ce145beb06042573 314 Pfam PF02272 DHHA1 domain 250 296 1.9E-5 T 21-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HSISS4_RS05820 75e6b872612dbf14ce145beb06042573 314 Pfam PF01368 DHH family 17 152 4.2E-11 T 21-04-2016 IPR001667 DDH domain HSISS4_RS05820 75e6b872612dbf14ce145beb06042573 314 Gene3D G3DSA:3.90.1640.10 15 189 6.7E-31 T 21-04-2016 HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 PANTHER PTHR10302 1 118 5.5E-35 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 SUPERFAMILY SSF50249 1 130 3.02E-40 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 114 5.2E-31 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 Hamap MF_00984 Single-stranded DNA-binding protein. 2 106 31.644 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 PIRSF PIRSF002070 1 121 3.5E-33 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 Gene3D G3DSA:2.40.50.140 1 117 2.2E-38 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08970 145f71b3320129e309e76d365c6a99b8 130 Pfam PF00436 Single-strand binding protein family 3 102 4.5E-30 T 21-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 HSISS4_RS07485 f11d369a9512818a465f86d9c0d91fcb 319 Pfam PF03631 Virulence factor BrkB 35 282 5.0E-45 T 21-04-2016 IPR017039 Virulence factor BrkB HSISS4_RS07485 f11d369a9512818a465f86d9c0d91fcb 319 PIRSF PIRSF035875 1 298 7.7E-59 T 21-04-2016 IPR017039 Virulence factor BrkB HSISS4_RS07485 f11d369a9512818a465f86d9c0d91fcb 319 PANTHER PTHR30213 6 292 1.9E-33 T 21-04-2016 HSISS4_RS07485 f11d369a9512818a465f86d9c0d91fcb 319 PANTHER PTHR30213:SF1 6 292 1.9E-33 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 Gene3D G3DSA:3.50.50.60 1 118 2.0E-32 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 SUPERFAMILY SSF51905 1 297 3.89E-49 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 Gene3D G3DSA:3.50.50.60 119 227 1.9E-31 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 Gene3D G3DSA:3.50.50.60 228 302 5.7E-13 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PANTHER PTHR22912:SF48 1 305 8.4E-135 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 266 284 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 231 252 1.2E-67 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 132 152 - T 21-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 292 2.1E-50 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 302 5.2E-114 T 21-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PANTHER PTHR22912 1 305 8.4E-135 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.2E-38 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 7.2E-38 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.2E-38 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 245 7.2E-38 T 21-04-2016 HSISS4_RS00590 9107c0087a1de218ca27a504fe69a42a 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 7.2E-38 T 21-04-2016 HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 SUPERFAMILY SSF56281 13 243 1.04E-43 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 Pfam PF12706 Beta-lactamase superfamily domain 29 214 4.2E-18 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 PANTHER PTHR13754:SF15 6 268 2.6E-104 T 21-04-2016 HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 Gene3D G3DSA:3.60.15.10 11 254 7.4E-40 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 SMART SM00849 17 197 1.6E-10 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04390 8856311f6b0f76c56694933003b91a3d 270 PANTHER PTHR13754 6 268 2.6E-104 T 21-04-2016 HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 100 730 1.4E-83 T 21-04-2016 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 Pfam PF00753 Metallo-beta-lactamase superfamily 493 699 6.5E-16 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 PANTHER PTHR30619 3 735 8.2E-145 T 21-04-2016 HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 Pfam PF13567 Domain of unknown function (DUF4131) 15 169 1.3E-8 T 21-04-2016 IPR025405 Domain of unknown function DUF4131 HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 SUPERFAMILY SSF56281 487 734 1.27E-47 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 Gene3D G3DSA:3.60.15.10 480 732 5.4E-39 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 SMART SM00849 495 701 1.5E-13 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 PANTHER PTHR30619:SF2 3 735 8.2E-145 T 21-04-2016 HSISS4_RS07510 18a398860f21d4a7bbda59afaee2c511 746 Pfam PF03772 Competence protein 216 462 9.3E-33 T 21-04-2016 IPR004477 ComEC/Rec2-related protein HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Gene3D G3DSA:3.40.120.10 24 214 4.9E-59 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Gene3D G3DSA:3.30.310.50 480 570 7.7E-27 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 180 2.1E-40 T 21-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Gene3D G3DSA:3.40.120.10 230 306 4.9E-23 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 SUPERFAMILY SSF53738 227 312 5.1E-20 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 SUPERFAMILY SSF55957 511 570 1.31E-15 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 SUPERFAMILY SSF55957 444 481 1.31E-15 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 138 147 - T 21-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 PANTHER PTHR22573:SF54 20 570 1.8E-232 T 21-04-2016 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Gene3D G3DSA:3.40.120.10 307 454 3.2E-37 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 505 556 2.2E-9 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 325 451 1.4E-22 T 21-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 SUPERFAMILY SSF53738 304 454 1.96E-30 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 222 311 6.5E-24 T 21-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 296 311 7.2E-5 T 21-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 137 151 7.2E-5 T 21-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 PANTHER PTHR22573 20 570 1.8E-232 T 21-04-2016 HSISS4_RS05695 38a87a8d21cac5cfdb9857614442a41c 572 SUPERFAMILY SSF53738 26 236 4.41E-46 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 9 177 2.4E-46 T 21-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 SUPERFAMILY SSF82679 7 118 8.11E-36 T 21-04-2016 IPR006645 NusG, N-terminal GO:0006355 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 PANTHER PTHR30265 2 179 3.3E-60 T 21-04-2016 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 SMART SM00738 6 117 3.9E-49 T 21-04-2016 IPR006645 NusG, N-terminal GO:0006355 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 PRINTS PR00338 Transcription termination factor NUSG signature 155 171 8.02E-8 T 21-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 PRINTS PR00338 Transcription termination factor NUSG signature 61 73 8.02E-8 T 21-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 6 179 21.204 T 21-04-2016 IPR001062 Transcription antitermination protein, NusG GO:0032784 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 Gene3D G3DSA:3.30.70.940 7 119 9.6E-43 T 21-04-2016 IPR006645 NusG, N-terminal GO:0006355 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 Pfam PF02357 Transcription termination factor nusG 7 114 3.5E-27 T 21-04-2016 IPR006645 NusG, N-terminal GO:0006355 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 Pfam PF00467 KOW motif 130 160 1.7E-7 T 21-04-2016 IPR005824 KOW HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 Gene3D G3DSA:2.30.30.30 124 178 2.5E-17 T 21-04-2016 IPR014722 Ribosomal protein L2 domain 2 HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 SMART SM00739 127 154 2.9E-6 T 21-04-2016 IPR005824 KOW HSISS4_RS01020 83209a4cfdcc62ceee9e63fb8a0c63c9 179 SUPERFAMILY SSF50104 117 177 1.02E-12 T 21-04-2016 IPR008991 Translation protein SH3-like domain HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 SUPERFAMILY SSF69065 6 129 1.92E-45 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 Pfam PF00636 Ribonuclease III domain 15 112 3.4E-16 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 SMART SM00535 3 132 0.0055 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 Gene3D G3DSA:1.10.1520.10 3 132 1.6E-53 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 PIRSF PIRSF005520 1 133 4.2E-52 T 21-04-2016 IPR008226 Mini-ribonuclease 3 family HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 4 130 28.664 T 21-04-2016 IPR008226 Mini-ribonuclease 3 family HSISS4_RS00530 8dba29c5c2a4168a87d2b8d49812b53e 133 PANTHER PTHR34276 6 132 2.1E-54 T 21-04-2016 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PANTHER PTHR12128:SF34 1 309 3.5E-121 T 21-04-2016 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 Gene3D G3DSA:3.20.20.70 11 291 6.4E-106 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 SUPERFAMILY SSF51569 11 291 1.05E-89 T 21-04-2016 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 11 291 3.1E-91 T 21-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 77 95 1.5E-29 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 135 152 1.5E-29 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 110 126 1.5E-29 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PRINTS PR00146 Dihydrodipicolinate synthase signature 41 62 1.5E-29 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 7 293 59.929 T 21-04-2016 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PIRSF PIRSF001365 9 302 7.9E-83 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 PANTHER PTHR12128 1 309 3.5E-121 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 140 170 - T 21-04-2016 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 SMART SM01130 8 296 1.5E-116 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05945 15a30041332784a8be447d195c267c0b 311 Pfam PF00701 Dihydrodipicolinate synthetase family 10 289 6.8E-84 T 21-04-2016 IPR002220 DapA-like GO:0008152|GO:0016829 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 Gene3D G3DSA:3.40.50.10680 76 321 3.6E-54 T 21-04-2016 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 6 320 1.1E-118 T 21-04-2016 IPR010119 Gluconeogenesis factor HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 Pfam PF01933 Uncharacterised protein family UPF0052 6 297 3.0E-93 T 21-04-2016 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 PANTHER PTHR30135 1 323 1.5E-131 T 21-04-2016 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 PANTHER PTHR30135:SF3 1 323 1.5E-131 T 21-04-2016 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 SUPERFAMILY SSF142338 3 317 1.83E-97 T 21-04-2016 HSISS4_RS05535 9beb740ec8b8909a47622ab1553c0a47 324 Hamap MF_00973 Gluconeogenesis factor. 2 322 34.026 T 21-04-2016 IPR010119 Gluconeogenesis factor HSISS4_RS03195 0476b7f69392a9c32c38b35a99d97b6f 338 Gene3D G3DSA:3.40.50.1980 70 197 5.5E-17 T 21-04-2016 HSISS4_RS03195 0476b7f69392a9c32c38b35a99d97b6f 338 Gene3D G3DSA:3.40.50.1980 198 336 9.7E-25 T 21-04-2016 HSISS4_RS03195 0476b7f69392a9c32c38b35a99d97b6f 338 SUPERFAMILY SSF53807 64 335 3.85E-43 T 21-04-2016 HSISS4_RS03195 0476b7f69392a9c32c38b35a99d97b6f 338 Pfam PF01497 Periplasmic binding protein 73 313 3.9E-50 T 21-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HSISS4_RS03195 0476b7f69392a9c32c38b35a99d97b6f 338 PANTHER PTHR30535 47 332 9.3E-25 T 21-04-2016 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Gene3D G3DSA:1.10.1140.10 351 466 7.6E-50 T 21-04-2016 IPR024034 ATPase, F1 complex beta subunit/V1 complex, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 8.3E-252 T 21-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 77 7.3E-21 T 21-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Gene3D G3DSA:3.40.50.300 80 349 1.5E-108 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 SUPERFAMILY SSF47917 351 466 1.2E-49 T 21-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 SMART SM00382 147 332 2.0E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 SUPERFAMILY SSF52540 81 353 5.33E-89 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Gene3D G3DSA:2.40.10.170 2 79 8.0E-30 T 21-04-2016 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 56.935 T 21-04-2016 IPR005722 ATPase, F1 complex, beta subunit GO:0015986|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 PANTHER PTHR15184 1 466 0.0 T 21-04-2016 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 SUPERFAMILY SSF50615 2 79 7.32E-23 T 21-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 21-04-2016 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 PANTHER PTHR15184:SF8 1 466 0.0 T 21-04-2016 HSISS4_RS02270 f49c71931ae0d77306d4093509b0908b 468 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 135 348 1.6E-67 T 21-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02540 7a1a5beadab1f871acb00baba511ac57 115 Pfam PF09966 Uncharacterized protein conserved in bacteria (DUF2200) 4 114 9.4E-48 T 21-04-2016 IPR014580 Uncharacterised conserved protein UCP033199 HSISS4_RS02540 7a1a5beadab1f871acb00baba511ac57 115 PIRSF PIRSF033199 1 115 5.4E-50 T 21-04-2016 IPR014580 Uncharacterised conserved protein UCP033199 HSISS4_RS02540 7a1a5beadab1f871acb00baba511ac57 115 Gene3D G3DSA:1.10.8.290 2 115 1.3E-52 T 21-04-2016 IPR023204 SP1917 domain HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 80 27.229 T 21-04-2016 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 PRINTS PR01249 Ribosomal protein L31 signature 2 19 9.1E-20 T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 PRINTS PR01249 Ribosomal protein L31 signature 44 59 9.1E-20 T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 PRINTS PR01249 Ribosomal protein L31 signature 59 77 9.1E-20 T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 ProSitePatterns PS01143 Ribosomal protein L31 signature. 48 69 - T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 PANTHER PTHR33280:SF2 1 79 1.1E-35 T 21-04-2016 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 Pfam PF01197 Ribosomal protein L31 1 78 1.5E-29 T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 PANTHER PTHR33280 1 79 1.1E-35 T 21-04-2016 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 79 1.3E-20 T 21-04-2016 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05830 6c82511a9287deb94bff1f6dc07237bc 80 SUPERFAMILY SSF143800 1 79 1.69E-24 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 TIGRFAM TIGR00416 sms: DNA repair protein RadA 13 410 1.8E-172 T 21-04-2016 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 Pfam PF13481 AAA domain 28 180 1.6E-15 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 171 199 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 41 69 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 82 99 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 280 303 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 206 232 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PRINTS PR01874 DNA repair protein radA signature 132 156 1.0E-76 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 SUPERFAMILY SSF52540 30 249 3.03E-49 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 SUPERFAMILY SSF54211 261 414 2.69E-40 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 SUPERFAMILY SSF54211 213 227 2.69E-40 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 Gene3D G3DSA:3.30.230.10 246 414 5.1E-35 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 SMART SM00382 49 202 6.4E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 Pfam PF13541 Subunit ChlI of Mg-chelatase 323 387 6.6E-9 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 PANTHER PTHR32472 2 414 2.3E-194 T 21-04-2016 HSISS4_RS08870 f0d6a098ec68bc3cdf6a23e49cb61634 415 Gene3D G3DSA:3.40.50.300 17 234 1.9E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Gene3D G3DSA:2.40.30.20 3 93 8.4E-35 T 21-04-2016 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 497 1.9E-249 T 21-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Gene3D G3DSA:3.40.50.300 94 371 1.7E-114 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 PIRSF PIRSF039088 1 501 2.7E-240 T 21-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.9E-71 T 21-04-2016 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 26 92 5.9E-16 T 21-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 PANTHER PTHR15184 1 486 1.7E-294 T 21-04-2016 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 494 1.3E-48 T 21-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 499 49.858 T 21-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 SUPERFAMILY SSF52540 95 370 9.62E-97 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 SUPERFAMILY SSF50615 10 94 3.14E-28 T 21-04-2016 IPR004100 ATPase, F1 complex alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 SUPERFAMILY SSF47917 372 497 9.68E-49 T 21-04-2016 IPR000793 ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal GO:0015991|GO:0016820|GO:0033178 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 Gene3D G3DSA:1.20.150.20 372 497 2.7E-51 T 21-04-2016 HSISS4_RS02260 d457e2f42c53ec70cf3b234d9dde1d6f 501 PANTHER PTHR15184:SF3 1 486 1.7E-294 T 21-04-2016 IPR005294 ATPase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PANTHER PTHR23115:SF184 794 942 4.2E-199 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 366 417 1.3E-13 T 21-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 2 49 2.8E-12 T 21-04-2016 IPR006847 Translation initiation factor IF-2, N-terminal HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 SUPERFAMILY SSF52540 432 619 1.87E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Gene3D G3DSA:3.40.50.300 441 606 1.1E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Gene3D G3DSA:2.40.30.10 621 708 2.2E-21 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 SUPERFAMILY SSF52156 723 853 1.57E-39 T 21-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Gene3D G3DSA:3.40.50.10050 746 825 1.8E-27 T 21-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 SUPERFAMILY SSF50447 847 944 5.98E-28 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Gene3D G3DSA:2.40.30.10 848 944 8.5E-35 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PRINTS PR00449 Transforming protein P21 ras signature 546 559 7.6E-5 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PRINTS PR00449 Transforming protein P21 ras signature 449 470 7.6E-5 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PRINTS PR00449 Transforming protein P21 ras signature 587 609 7.6E-5 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PRINTS PR00449 Transforming protein P21 ras signature 488 510 7.6E-5 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 944 16.893 T 21-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PANTHER PTHR23115 422 770 4.2E-199 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PANTHER PTHR23115 794 942 4.2E-199 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 449 605 5.6E-35 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Pfam PF11987 Translation-initiation factor 2 732 836 3.4E-37 T 21-04-2016 IPR023115 Translation initiation factor IF- 2, domain 3 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 SUPERFAMILY SSF50447 621 701 1.67E-22 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 PANTHER PTHR23115:SF184 422 770 4.2E-199 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 359 944 2.9E-248 T 21-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 Pfam PF00009 Elongation factor Tu GTP binding domain 450 607 2.1E-34 T 21-04-2016 HSISS4_RS01560 82bb8ebc468b7adfaa9a610bf05f1151 944 ProSitePatterns PS01176 Initiation factor 2 signature. 897 919 - T 21-04-2016 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 214 1.7E-83 T 21-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 SUPERFAMILY SSF51366 3 215 1.94E-72 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 Gene3D G3DSA:3.20.20.70 2 218 2.7E-96 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 PANTHER PTHR11749 1 219 2.0E-122 T 21-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 134 156 - T 21-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 201 1.1E-76 T 21-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 32 46 - T 21-04-2016 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS08620 e537a40da78f7aebe24e71674f779c9f 219 PIRSF PIRSF001461 1 219 7.3E-90 T 21-04-2016 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PANTHER PTHR30075:SF2 1 678 0.0 T 21-04-2016 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 Gene3D G3DSA:1.10.3210.10 359 462 9.8E-4 T 21-04-2016 IPR006674 HD domain HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 2 675 5.6E-217 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 5 546 2.2E-198 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 Pfam PF05746 DALR anticodon binding domain 579 660 3.3E-5 T 21-04-2016 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 SUPERFAMILY SSF109604 335 491 5.23E-18 T 21-04-2016 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 2 675 26.54 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PANTHER PTHR30075 1 678 0.0 T 21-04-2016 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 314 330 8.2E-32 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 6 19 8.2E-32 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 393 412 8.2E-32 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 242 257 8.2E-32 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02380 34fbf6bcd9e7028ebef7a8725ad22bf9 678 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 49 61 8.2E-32 T 21-04-2016 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 SUPERFAMILY SSF53271 10 161 6.38E-55 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 PANTHER PTHR10210 1 322 1.2E-161 T 21-04-2016 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 10 126 4.1E-49 T 21-04-2016 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 Gene3D G3DSA:3.40.50.2020 166 287 8.8E-41 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 PANTHER PTHR10210:SF41 1 322 1.2E-161 T 21-04-2016 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 Gene3D G3DSA:3.40.50.2020 5 165 1.1E-75 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 SUPERFAMILY SSF53271 112 307 1.24E-42 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 Pfam PF14572 Phosphoribosyl synthetase-associated domain 212 316 3.2E-21 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 316 2.0E-104 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 10 317 44.427 T 21-04-2016 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|UniPathway: UPA00087 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 134 149 - T 21-04-2016 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: REACT_474|UniPathway: UPA00087 HSISS4_RS07035 2de025c1dd421506182ea47c8520c389 323 SMART SM01400 10 126 4.2E-77 T 21-04-2016 HSISS4_RS01680 3c12545882d21a92bddf6db6e51ad634 220 PANTHER PTHR11907 30 220 1.3E-40 T 21-04-2016 HSISS4_RS01680 3c12545882d21a92bddf6db6e51ad634 220 Gene3D G3DSA:3.40.50.2020 54 214 6.0E-16 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01680 3c12545882d21a92bddf6db6e51ad634 220 Gene3D G3DSA:3.10.370.10 18 53 4.8E-4 T 21-04-2016 HSISS4_RS01680 3c12545882d21a92bddf6db6e51ad634 220 SUPERFAMILY SSF53271 45 219 8.09E-18 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01680 3c12545882d21a92bddf6db6e51ad634 220 PANTHER PTHR11907:SF9 30 220 1.3E-40 T 21-04-2016 HSISS4_RS06295 fd90509af5568845090d5bac5f462194 149 SUPERFAMILY SSF46785 5 137 2.62E-30 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06295 fd90509af5568845090d5bac5f462194 149 Pfam PF02082 Transcriptional regulator 1 83 1.6E-22 T 21-04-2016 IPR000944 Transcription regulator Rrf2-type HSISS4_RS06295 fd90509af5568845090d5bac5f462194 149 Gene3D G3DSA:1.10.10.10 1 145 1.0E-49 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06295 fd90509af5568845090d5bac5f462194 149 PANTHER PTHR33221 2 146 1.3E-62 T 21-04-2016 HSISS4_RS06295 fd90509af5568845090d5bac5f462194 149 PANTHER PTHR33221:SF5 2 146 1.3E-62 T 21-04-2016 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 322 343 - T 21-04-2016 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 PANTHER PTHR11063 1 416 3.0E-174 T 21-04-2016 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 SUPERFAMILY SSF53720 3 415 4.97E-113 T 21-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 415 40.761 T 21-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 PIRSF PIRSF000151 1 416 1.7E-179 T 21-04-2016 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 PANTHER PTHR11063:SF8 1 416 3.0E-174 T 21-04-2016 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Pfam PF00171 Aldehyde dehydrogenase family 316 378 6.5E-8 T 21-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Pfam PF00171 Aldehyde dehydrogenase family 7 283 5.8E-13 T 21-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Gene3D G3DSA:3.40.309.10 225 373 1.7E-45 T 21-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Gene3D G3DSA:3.40.605.10 374 415 1.5E-99 T 21-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 Gene3D G3DSA:3.40.605.10 3 222 1.5E-99 T 21-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08185 dba0c2c37b221e1757fbe550f912cf56 416 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 11 405 2.7E-155 T 21-04-2016 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PRINTS PR00125 ATP synthase delta subunit signature 137 152 6.4E-18 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PRINTS PR00125 ATP synthase delta subunit signature 152 170 6.4E-18 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 6.4E-18 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PRINTS PR00125 ATP synthase delta subunit signature 8 27 6.4E-18 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 6.4E-18 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 4 178 15.859 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 Gene3D G3DSA:1.10.520.20 8 104 6.2E-15 T 21-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 SUPERFAMILY SSF47928 5 106 2.48E-19 T 21-04-2016 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 10 176 2.5E-33 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 PANTHER PTHR11910 12 178 9.3E-32 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS02255 a882581c18c84a0eb6073ff21005d440 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 10 177 9.2E-38 T 21-04-2016 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Pfam PF01018 GTP1/OBG 4 159 2.1E-61 T 21-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PIRSF PIRSF002401 1 385 4.2E-139 T 21-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Pfam PF01926 50S ribosome-binding GTPase 162 285 7.1E-22 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Gene3D G3DSA:3.40.50.300 161 343 1.5E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 367 436 3.4E-26 T 21-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 4.2E-34 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 212 227 4.2E-34 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 4.2E-34 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 229 247 4.2E-34 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Hamap MF_01454 GTPase Obg [obg]. 3 338 46.99 T 21-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 337 1.7E-139 T 21-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 SUPERFAMILY SSF102741 364 437 3.27E-24 T 21-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PANTHER PTHR11702:SF3 4 346 5.3E-162 T 21-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PANTHER PTHR11702:SF3 424 437 5.3E-162 T 21-04-2016 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 SUPERFAMILY SSF82051 3 159 1.44E-54 T 21-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 ProSitePatterns PS00905 GTP1/OBG family signature. 214 227 - T 21-04-2016 IPR006074 GTP1/OBG, conserved site GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 162 330 5.8E-12 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 SUPERFAMILY SSF52540 152 341 5.36E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Pfam PF09269 Domain of unknown function (DUF1967) 367 435 1.1E-25 T 21-04-2016 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 Gene3D G3DSA:2.70.210.12 3 157 1.6E-58 T 21-04-2016 IPR006169 GTP1/OBG domain GO:0005525 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PANTHER PTHR11702 4 346 5.3E-162 T 21-04-2016 HSISS4_RS07220 35246e0b674007c7efad5ec5deeb8dbf 437 PANTHER PTHR11702 424 437 5.3E-162 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Gene3D G3DSA:3.20.20.140 635 811 1.0E-56 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Gene3D G3DSA:3.20.20.140 337 422 1.0E-56 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 235 1460 0.0 T 21-04-2016 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF11490 DNA polymerase III polC-type N-terminus II 92 203 6.0E-14 T 21-04-2016 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF02811 PHP domain 341 699 1.4E-47 T 21-04-2016 IPR004013 PHP domain GO:0003824 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044 944 1085 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044 841 926 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044 1123 1436 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044 22 555 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 421 639 1.1E-39 T 21-04-2016 IPR006054 DNA polymerase III, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Gene3D G3DSA:2.40.50.140 229 327 1.7E-7 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 SUPERFAMILY SSF53098 425 891 3.12E-94 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 SMART SM00481 340 407 2.3E-24 T 21-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Gene3D G3DSA:1.10.150.280 1398 1447 1.0E-7 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1464 417.779 T 21-04-2016 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 841 1269 5.4E-90 T 21-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044:SF26 944 1085 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044:SF26 841 926 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044:SF26 1123 1436 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 PANTHER PTHR23044:SF26 22 555 0.0 T 21-04-2016 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 SMART SM00479 425 591 3.3E-44 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 SUPERFAMILY SSF50249 238 326 9.14E-14 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Gene3D G3DSA:3.30.420.10 423 594 3.7E-58 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF00929 Exonuclease 427 581 9.6E-34 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF14480 DNA polymerase III polC-type N-terminus I 4 78 9.0E-12 T 21-04-2016 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00435 379a010438a5405295b4a97fd6634f6c 1464 Pfam PF14579 Helix-hairpin-helix motif 1377 1453 1.0E-6 T 21-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 Gene3D G3DSA:3.10.290.10 1 66 3.6E-20 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 SUPERFAMILY SSF55174 2 66 6.92E-16 T 21-04-2016 HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 PANTHER PTHR32319:SF3 4 100 7.1E-29 T 21-04-2016 HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 Pfam PF13275 S4 domain 4 66 3.5E-24 T 21-04-2016 HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 2 60 1.9E-27 T 21-04-2016 IPR014330 RNA-binding S4-related,YaaA HSISS4_RS09680 f3c8046ae3e455bd08618e9ff0d896ef 125 PANTHER PTHR32319 4 100 7.1E-29 T 21-04-2016 HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 Pfam PF00005 ABC transporter 20 162 8.3E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 SMART SM00382 29 227 6.4E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 PANTHER PTHR24220 6 253 4.2E-91 T 21-04-2016 HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 Gene3D G3DSA:3.40.50.300 2 228 2.9E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 SUPERFAMILY SSF52540 4 221 3.88E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06310 a54763e39cd8590c0c95e0a51e08c32f 306 PANTHER PTHR24220:SF523 6 253 4.2E-91 T 21-04-2016 HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 Pfam PF00271 Helicase conserved C-terminal domain 290 397 1.2E-12 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 Gene3D G3DSA:3.40.50.300 290 411 5.5E-17 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 SMART SM00490 315 398 1.7E-9 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 SUPERFAMILY SSF52540 269 408 1.08E-29 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 SUPERFAMILY SSF52540 111 242 1.08E-29 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 Pfam PF04851 Type III restriction enzyme, res subunit 94 169 1.2E-6 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 Gene3D G3DSA:3.40.50.300 86 252 1.3E-19 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 Gene3D G3DSA:3.30.40.10 30 63 0.001 T 21-04-2016 IPR013083 Zinc finger, RING/FYVE/PHD-type HSISS4_RS01675 2fedf6d8627b91523b71dd3be780992b 439 SMART SM00487 91 274 1.9E-9 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 PANTHER PTHR11361:SF14 5 593 6.2E-218 T 21-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SMART SM00463 704 782 1.2E-19 T 21-04-2016 IPR002625 Smr domain HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SUPERFAMILY SSF160443 705 780 1.06E-10 T 21-04-2016 IPR002625 Smr domain HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SUPERFAMILY SSF52540 287 506 1.38E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SUPERFAMILY SSF48334 31 276 4.32E-28 T 21-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 Gene3D G3DSA:3.40.50.300 287 506 7.8E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 781 19.709 T 21-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 PANTHER PTHR11361 5 593 6.2E-218 T 21-04-2016 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 TIGRFAM TIGR01069 mutS2: MutS2 family protein 1 781 1.8E-212 T 21-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 Pfam PF00488 MutS domain V 324 505 4.8E-36 T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 Pfam PF01713 Smr domain 707 781 4.3E-19 T 21-04-2016 IPR002625 Smr domain HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 PIRSF PIRSF005814 1 782 4.5E-251 T 21-04-2016 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SMART SM00533 13 310 1.1E-5 T 21-04-2016 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 SMART SM00534 321 506 3.4E-70 T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS08485 27f09089a44b6bc9b77fddf40c6754e8 782 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 403 419 - T 21-04-2016 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS08610 957582c41bd229d7d45acfe7c9c59580 424 SUPERFAMILY SSF58113 31 158 2.22E-5 T 21-04-2016 HSISS4_RS08610 957582c41bd229d7d45acfe7c9c59580 424 PANTHER PTHR30563 1 424 2.1E-97 T 21-04-2016 HSISS4_RS08610 957582c41bd229d7d45acfe7c9c59580 424 Pfam PF02646 RmuC family 117 407 6.4E-76 T 21-04-2016 IPR003798 DNA recombination RmuC HSISS4_RS08610 957582c41bd229d7d45acfe7c9c59580 424 Gene3D G3DSA:1.20.120.20 21 131 3.5E-4 T 21-04-2016 HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 Gene3D G3DSA:3.40.50.300 2 204 2.1E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 Pfam PF00271 Helicase conserved C-terminal domain 229 337 4.0E-25 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 SUPERFAMILY SSF52540 69 358 7.28E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 PANTHER PTHR24031:SF280 1 440 6.8E-216 T 21-04-2016 HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 Pfam PF00270 DEAD/DEAH box helicase 25 191 1.6E-43 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 SMART SM00490 256 337 7.3E-27 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 SMART SM00487 20 220 1.2E-51 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 Gene3D G3DSA:3.40.50.300 205 360 1.6E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 PANTHER PTHR24031 1 440 6.8E-216 T 21-04-2016 HSISS4_RS08135 4bd9d733edb30d9d5414ef632c876461 447 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 1 435 51.491 T 21-04-2016 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 PANTHER PTHR11206 5 439 2.0E-149 T 21-04-2016 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 PANTHER PTHR11206:SF107 5 439 2.0E-149 T 21-04-2016 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 Pfam PF01554 MatE 23 182 3.3E-35 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 Pfam PF01554 MatE 247 399 9.5E-22 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 23 416 2.4E-54 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS05105 a702b82b80beea392d4b956d855d4df9 446 PIRSF PIRSF006603 1 442 2.0E-86 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 PANTHER PTHR11082:SF25 1 321 6.0E-132 T 21-04-2016 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 PANTHER PTHR11082 1 321 6.0E-132 T 21-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 Pfam PF01207 Dihydrouridine synthase (Dus) 20 316 3.9E-86 T 21-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 Gene3D G3DSA:3.20.20.70 14 253 2.6E-82 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 102 120 - T 21-04-2016 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 PIRSF PIRSF006621 7 324 5.0E-102 T 21-04-2016 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 Gene3D G3DSA:1.10.1200.80 260 323 1.7E-19 T 21-04-2016 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 321 8.6E-105 T 21-04-2016 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 HSISS4_RS00895 6931db62e9f705bc039c817ec04c1458 325 SUPERFAMILY SSF51395 17 323 1.26E-83 T 21-04-2016 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 SUPERFAMILY SSF89550 150 162 4.71E-10 T 21-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 SUPERFAMILY SSF89550 9 88 4.71E-10 T 21-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 Pfam PF02811 PHP domain 7 96 4.8E-17 T 21-04-2016 IPR004013 PHP domain GO:0003824 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 SMART SM00481 3 70 2.5E-11 T 21-04-2016 IPR003141 Polymerase/histidinol phosphatase, N-terminal GO:0003677|GO:0003887|GO:0006260 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 Gene3D G3DSA:3.20.20.140 9 88 3.1E-10 T 21-04-2016 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 240 656 2.3E-156 T 21-04-2016 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 PANTHER PTHR32294:SF0 1 1036 0.0 T 21-04-2016 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 PANTHER PTHR32294 1 1036 0.0 T 21-04-2016 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 Pfam PF14579 Helix-hairpin-helix motif 730 813 3.0E-12 T 21-04-2016 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 Gene3D G3DSA:2.40.50.140 879 968 7.9E-8 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS04145 66117b4e3a098899a882bbd76b5f5ef9 1036 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 143 927 3.7E-215 T 21-04-2016 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08220 387afdd159c3818a1a3f5d5d2524b818 457 PANTHER PTHR40448:SF1 4 457 6.7E-25 T 21-04-2016 HSISS4_RS08220 387afdd159c3818a1a3f5d5d2524b818 457 PANTHER PTHR40448 4 457 6.7E-25 T 21-04-2016 HSISS4_RS08220 387afdd159c3818a1a3f5d5d2524b818 457 Pfam PF14501 GHKL domain 353 456 1.4E-10 T 21-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 529 749 1.3E-30 T 21-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731 168 212 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731 263 399 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731 436 534 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 SMART SM00939 514 752 1.2E-57 T 21-04-2016 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 SMART SM00940 1 143 1.9E-69 T 21-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731:SF148 168 212 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731:SF148 263 399 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PANTHER PTHR11731:SF148 436 534 1.7E-48 T 21-04-2016 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 182 500 2.1E-75 T 21-04-2016 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Gene3D G3DSA:3.40.50.1820 455 540 2.6E-51 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Gene3D G3DSA:3.40.50.1820 263 381 2.6E-51 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Gene3D G3DSA:3.40.50.1820 161 213 2.6E-51 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 SUPERFAMILY SSF49785 549 755 5.95E-71 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 SUPERFAMILY SSF81761 1 144 2.22E-41 T 21-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Gene3D G3DSA:2.60.120.260 541 637 1.4E-64 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Gene3D G3DSA:2.60.120.260 675 754 1.4E-64 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 168 178 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 720 735 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 506 522 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 152 164 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 200 216 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 186 195 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 371 387 1.3E-39 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Pfam PF09168 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal 1 142 1.8E-40 T 21-04-2016 IPR015251 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal domain GO:0006508|GO:0008239 HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 SUPERFAMILY SSF53474 148 550 6.6E-92 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS08070 203b3f655f72e995ee1899359ece37c7 755 Hamap MF_00698 Xaa-Pro dipeptidyl-peptidase [pepX]. 1 755 36.147 T 21-04-2016 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 Pfam PF00005 ABC transporter 19 164 2.8E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 PANTHER PTHR24220 5 235 3.6E-131 T 21-04-2016 HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 SMART SM00382 28 215 3.3E-6 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 PIRSF PIRSF039137 1 236 2.9E-109 T 21-04-2016 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 SUPERFAMILY SSF52540 3 234 1.11E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 Gene3D G3DSA:3.40.50.300 3 231 1.1E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01655 b87f1e838b70a8d91a2a1d5ca7d4a49e 236 PANTHER PTHR24220:SF568 5 235 3.6E-131 T 21-04-2016 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 TIGRFAM TIGR00059 L17: ribosomal protein bL17 3 128 1.6E-47 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 Pfam PF01196 Ribosomal protein L17 17 128 3.3E-39 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 128 27.55 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 SUPERFAMILY SSF64263 2 128 4.06E-43 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 PANTHER PTHR14413:SF5 1 67 2.5E-55 T 21-04-2016 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 PANTHER PTHR14413:SF5 84 128 2.5E-55 T 21-04-2016 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 Gene3D G3DSA:3.90.1030.10 2 128 8.1E-49 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 PANTHER PTHR14413 1 67 2.5E-55 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 PANTHER PTHR14413 84 128 2.5E-55 T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09220 7b83b958b0053f1edb2bc112d1060def 128 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 21-04-2016 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 144 3.1E-58 T 21-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 PANTHER PTHR10472 2 145 1.5E-74 T 21-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 SUPERFAMILY SSF69500 1 144 4.45E-58 T 21-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 Gene3D G3DSA:3.50.80.10 1 144 9.9E-60 T 21-04-2016 IPR023509 D-Tyr tRNAtyr deacylase-like domain HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 143 3.9E-55 T 21-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HSISS4_RS00785 61c50b01d676a04b09e3caad5eae5dd7 147 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 144 34.983 T 21-04-2016 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0005737|GO:0016788|GO:0019478 HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 71 7.6E-9 T 21-04-2016 IPR025966 Oligopeptide transport permease C-like, N-terminal domain HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 SUPERFAMILY SSF161098 102 287 6.02E-20 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 PANTHER PTHR30465:SF75 21 308 2.2E-148 T 21-04-2016 HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 PANTHER PTHR30465 21 308 2.2E-148 T 21-04-2016 HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 Gene3D G3DSA:1.10.3720.10 101 302 1.6E-17 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06990 bf110e0d7d653f5fedd6b3cae420aa17 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 306 8.3E-21 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 Pfam PF05193 Peptidase M16 inactive domain 183 361 3.7E-11 T 21-04-2016 IPR007863 Peptidase M16, C-terminal HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 SUPERFAMILY SSF63411 258 414 7.86E-15 T 21-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 Pfam PF00675 Insulinase (Peptidase family M16) 62 157 1.6E-13 T 21-04-2016 IPR011765 Peptidase M16, N-terminal HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 PANTHER PTHR11851:SF134 21 422 5.0E-69 T 21-04-2016 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 Gene3D G3DSA:3.30.830.10 64 222 2.6E-33 T 21-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 Gene3D G3DSA:3.30.830.10 259 415 7.4E-10 T 21-04-2016 IPR011237 Peptidase M16 domain GO:0046872 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 SUPERFAMILY SSF63411 20 221 2.02E-34 T 21-04-2016 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 HSISS4_RS09670 83205c98e90127083750fff1dff5c14b 425 PANTHER PTHR11851 21 422 5.0E-69 T 21-04-2016 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 SUPERFAMILY SSF52540 167 339 8.93E-14 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 PIRSF PIRSF004776 1 368 1.4E-83 T 21-04-2016 IPR016429 Bifunctional transcriptional regulator NadR GO:0045892 KEGG: 00760+2.7.7.1+2.7.1.22|UniPathway: UPA00253|UniPathway: UPA00253 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 Pfam PF13521 AAA domain 174 335 1.9E-18 T 21-04-2016 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 SUPERFAMILY SSF52374 9 159 4.02E-20 T 21-04-2016 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 Gene3D G3DSA:3.40.50.300 172 344 2.2E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 Gene3D G3DSA:3.40.50.620 9 171 1.0E-39 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 PANTHER PTHR37512 9 343 1.3E-23 T 21-04-2016 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 Pfam PF01467 Cytidylyltransferase-like 14 96 2.3E-7 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS01960 dc90daf9ee9a51280b9854733bfeddc7 368 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 11 75 2.0E-10 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 16 248 40.885 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 Pfam PF01255 Putative undecaprenyl diphosphate synthase 23 247 3.5E-82 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 SUPERFAMILY SSF64005 13 242 7.98E-90 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 PANTHER PTHR10291 16 249 3.5E-125 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 193 210 - T 21-04-2016 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 Gene3D G3DSA:3.40.1180.10 13 248 4.8E-100 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS00955 ac2d1addc061dbc9b353331409469e5a 249 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 16 247 3.6E-86 T 21-04-2016 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 HSISS4_RS02660 13c36d8302a05db6182a0ec1e4e0dc4a 332 PANTHER PTHR12526 43 332 4.0E-31 T 21-04-2016 HSISS4_RS02660 13c36d8302a05db6182a0ec1e4e0dc4a 332 Pfam PF13439 Glycosyltransferase Family 4 42 139 4.1E-16 T 21-04-2016 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain HSISS4_RS02660 13c36d8302a05db6182a0ec1e4e0dc4a 332 SUPERFAMILY SSF53756 11 330 4.76E-47 T 21-04-2016 HSISS4_RS02660 13c36d8302a05db6182a0ec1e4e0dc4a 332 Gene3D G3DSA:3.40.50.2000 126 268 6.9E-16 T 21-04-2016 HSISS4_RS02660 13c36d8302a05db6182a0ec1e4e0dc4a 332 Pfam PF00534 Glycosyl transferases group 1 152 299 1.7E-9 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Gene3D G3DSA:3.30.1360.10 2 56 8.1E-12 T 21-04-2016 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Gene3D G3DSA:1.10.150.20 244 311 6.4E-32 T 21-04-2016 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 150 2.2E-24 T 21-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 238 302 6.0E-28 T 21-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 219 1.6E-20 T 21-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 PANTHER PTHR32108 1 312 1.1E-135 T 21-04-2016 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 PANTHER PTHR32108:SF0 1 312 1.1E-135 T 21-04-2016 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 36.196 T 21-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 18 310 1.9E-116 T 21-04-2016 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 SMART SM00662 18 225 6.7E-90 T 21-04-2016 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 SUPERFAMILY SSF47789 245 311 2.22E-23 T 21-04-2016 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 Gene3D G3DSA:2.170.120.12 57 168 5.1E-46 T 21-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 251 309 9.0E-27 T 21-04-2016 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 SUPERFAMILY SSF56553 48 169 2.09E-42 T 21-04-2016 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 SUPERFAMILY SSF55257 4 48 1.63E-29 T 21-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09225 0e7860f3cef303736582cca13a89f7a3 312 SUPERFAMILY SSF55257 170 224 1.63E-29 T 21-04-2016 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 PANTHER PTHR19288 2 253 1.2E-88 T 21-04-2016 HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 PANTHER PTHR19288:SF3 2 253 1.2E-88 T 21-04-2016 HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 SUPERFAMILY SSF56784 3 252 9.8E-69 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 Gene3D G3DSA:3.40.50.1000 178 251 2.2E-36 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 Gene3D G3DSA:3.40.50.1000 2 80 2.2E-36 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 8.9E-21 T 21-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 Pfam PF13242 HAD-hyrolase-like 179 251 5.0E-16 T 21-04-2016 HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 Gene3D G3DSA:3.40.50.10410 85 177 5.0E-38 T 21-04-2016 IPR023215 Nitrophenylphosphatase-like domain HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 3 252 2.0E-118 T 21-04-2016 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 HSISS4_RS03855 9f49f06df1c3a8d3b40481b8ef053115 257 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 228 5.4E-37 T 21-04-2016 IPR006357 HAD-superfamily hydrolase, subfamily IIA HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 336 505 8.7E-19 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 290 399 4.8E-21 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Gene3D G3DSA:3.40.190.10 25 116 2.4E-32 T 21-04-2016 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Gene3D G3DSA:3.40.190.10 226 259 2.4E-32 T 21-04-2016 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Gene3D G3DSA:1.10.3720.10 289 506 1.5E-56 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 SUPERFAMILY SSF161098 291 490 1.57E-44 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 SMART SM00062 27 266 5.0E-32 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 256 2.3E-35 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 PANTHER PTHR30614:SF15 19 510 1.4E-138 T 21-04-2016 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 PANTHER PTHR30614 19 510 1.4E-138 T 21-04-2016 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 SUPERFAMILY SSF53850 1 255 8.64E-43 T 21-04-2016 HSISS4_RS00835 b1696f6d9ca6dde7622f1e31b6570bc7 515 Gene3D G3DSA:3.40.190.10 117 211 5.9E-12 T 21-04-2016 HSISS4_RS06170 ab177781662c9756dbf0354cfdb3311c 178 PANTHER PTHR33795 1 170 2.0E-51 T 21-04-2016 HSISS4_RS06170 ab177781662c9756dbf0354cfdb3311c 178 SUPERFAMILY SSF46689 54 154 1.52E-14 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06170 ab177781662c9756dbf0354cfdb3311c 178 Gene3D G3DSA:1.10.10.60 59 152 2.0E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06170 ab177781662c9756dbf0354cfdb3311c 178 PANTHER PTHR33795:SF1 1 170 2.0E-51 T 21-04-2016 HSISS4_RS06170 ab177781662c9756dbf0354cfdb3311c 178 Pfam PF01527 Transposase 53 145 2.2E-7 T 21-04-2016 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Pfam PF01473 Putative cell wall binding repeat 607 621 0.24 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Pfam PF01473 Putative cell wall binding repeat 340 355 0.041 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Pfam PF01473 Putative cell wall binding repeat 152 164 0.0038 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 SUPERFAMILY SSF69360 557 643 1.29E-23 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.10.270.10 249 311 4.2E-14 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.10.270.10 394 443 8.1E-6 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.10.270.10 150 234 7.8E-19 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 253 312 8.7E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 570 631 3.6E-26 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 157 218 3.2E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.20.120.10 538 582 2.4E-7 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 5.9E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.10.270.10 583 643 5.4E-20 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 Gene3D G3DSA:2.10.270.10 329 383 4.6E-11 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 SUPERFAMILY SSF69360 250 428 3.45E-37 T 21-04-2016 HSISS4_RS06585 df902d24bd9a1e518f3d206a86854713 647 SUPERFAMILY SSF69360 151 215 3.45E-37 T 21-04-2016 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 PANTHER PTHR24220 3 276 4.8E-103 T 21-04-2016 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 Pfam PF00005 ABC transporter 20 166 1.7E-33 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 PANTHER PTHR24220:SF435 3 276 4.8E-103 T 21-04-2016 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 SUPERFAMILY SSF52540 1 228 4.83E-65 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 SMART SM00382 29 214 5.8E-15 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 2 270 4.2E-116 T 21-04-2016 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS09655 dd3559e65ec68ec7f25b080053bb7e7c 276 Gene3D G3DSA:3.40.50.300 1 229 5.8E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 Pfam PF00471 Ribosomal protein L33 3 49 2.2E-18 T 21-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 PANTHER PTHR15238:SF3 1 49 7.0E-17 T 21-04-2016 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 SUPERFAMILY SSF57829 1 49 2.08E-15 T 21-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 21-04-2016 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.0E-17 T 21-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 PANTHER PTHR15238 1 49 7.0E-17 T 21-04-2016 HSISS4_RS09485 730ff54406fcf7615d7f35d1ea9e2a42 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 15.717 T 21-04-2016 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 SUPERFAMILY SSF56059 483 616 1.27E-25 T 21-04-2016 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 SUPERFAMILY SSF56059 652 742 1.27E-25 T 21-04-2016 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 TIGRFAM TIGR01435 glu_cys_lig_rel: glutamate--cysteine ligase/glutathione synthase 16 745 3.2E-247 T 21-04-2016 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142|UniPathway: UPA00142 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 Gene3D G3DSA:3.30.470.20 665 698 7.7E-10 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 Gene3D G3DSA:3.30.470.20 480 604 7.7E-10 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 482 578 2.2E-4 T 21-04-2016 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|UniPathway: UPA00074 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 SUPERFAMILY SSF55931 2 454 1.83E-137 T 21-04-2016 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 Hamap MF_00782 Glutathione biosynthesis bifunctional protein GshAB [gshAB]. 1 754 413.721 T 21-04-2016 IPR006335 Glutathione biosynthesis bifunctional protein GshAB GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142|UniPathway: UPA00142 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 PANTHER PTHR38761 1 464 6.6E-52 T 21-04-2016 HSISS4_RS06815 08a2e10cb92941c6ccc00ea0d62704d5 754 Pfam PF04262 Glutamate-cysteine ligase 7 321 1.5E-72 T 21-04-2016 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255|UniPathway: UPA00142 HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 SUPERFAMILY SSF47781 17 90 1.89E-5 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 Pfam PF04002 RadC-like JAB domain 105 222 8.4E-40 T 21-04-2016 IPR025657 RadC-like JAB domain HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 174 179 - T 21-04-2016 IPR020891 Uncharacterised protein family UPF0758, conserved site HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 PANTHER PTHR30471:SF3 1 225 1.2E-88 T 21-04-2016 HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 SUPERFAMILY SSF102712 168 195 6.02E-5 T 21-04-2016 HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 PANTHER PTHR30471 1 225 1.2E-88 T 21-04-2016 HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 TIGRFAM TIGR00608 radc: DNA repair protein RadC 13 222 1.5E-71 T 21-04-2016 IPR001405 RadC protein HSISS4_RS07060 cba9b55ec9958757f1a91a00f71db4df 228 Gene3D G3DSA:3.40.140.10 102 222 1.2E-43 T 21-04-2016 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 PANTHER PTHR33238:SF1 1 213 1.9E-66 T 21-04-2016 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 PANTHER PTHR33238 1 213 1.9E-66 T 21-04-2016 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 Pfam PF04023 FeoA domain 153 213 2.7E-4 T 21-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 130 7.9E-25 T 21-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 SUPERFAMILY SSF47979 62 136 3.53E-23 T 21-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 SMART SM00529 23 122 3.2E-37 T 21-04-2016 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 SUPERFAMILY SSF46785 1 60 3.71E-14 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 Gene3D G3DSA:1.10.10.10 1 66 3.1E-23 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 Gene3D G3DSA:1.10.60.10 72 135 1.4E-28 T 21-04-2016 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 HSISS4_RS03540 c9486e162446d89322fefffdf9abcf2b 215 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 2 58 4.2E-15 T 21-04-2016 IPR022687 DTXR-type HTH domain GO:0003677 HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 Pfam PF00561 alpha/beta hydrolase fold 26 250 9.5E-16 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 Gene3D G3DSA:3.40.50.1820 14 265 1.5E-40 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 PANTHER PTHR10992 16 264 1.0E-28 T 21-04-2016 HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 SUPERFAMILY SSF53474 11 263 9.42E-41 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 5.0E-7 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 5.0E-7 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS02575 ec30b1fbec8e32190456689cac091f96 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 5.0E-7 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SMART SM00091 93 159 2.2E-8 T 21-04-2016 IPR000014 PAS domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Gene3D G3DSA:1.10.287.130 199 260 7.4E-20 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Gene3D G3DSA:3.30.450.20 88 198 3.2E-12 T 21-04-2016 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 435 5.9E-28 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PANTHER PTHR24423 1 9 1.3E-185 T 21-04-2016 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PANTHER PTHR24423 76 446 1.3E-185 T 21-04-2016 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SMART SM00388 207 273 7.7E-20 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SUPERFAMILY SSF47384 193 273 1.96E-19 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 272 6.6E-17 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SUPERFAMILY SSF55874 262 434 8.25E-46 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Gene3D G3DSA:3.30.565.10 261 435 4.4E-49 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SUPERFAMILY SSF55785 83 199 4.01E-13 T 21-04-2016 IPR000014 PAS domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 Pfam PF00989 PAS fold 94 197 2.1E-7 T 21-04-2016 IPR013767 PAS fold GO:0006355 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 SMART SM00387 324 436 4.7E-40 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 414 4.0E-20 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 433 4.0E-20 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 389 4.0E-20 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PRINTS PR00344 Bacterial sensor protein C-terminal signature 361 375 4.0E-20 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PANTHER PTHR24423:SF568 1 9 1.3E-185 T 21-04-2016 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 PANTHER PTHR24423:SF568 76 446 1.3E-185 T 21-04-2016 HSISS4_RS04385 ebb95b8ac4dc062157fb491624fe9055 446 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 90 207 7.7E-7 T 21-04-2016 IPR000014 PAS domain HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 SUPERFAMILY SSF51182 1 312 1.48E-106 T 21-04-2016 IPR011051 RmlC-like cupin domain HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 312 4.0E-45 T 21-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 PANTHER PTHR18964 1 255 3.6E-110 T 21-04-2016 HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 Gene3D G3DSA:2.60.120.10 226 313 2.4E-32 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 Pfam PF01238 Phosphomannose isomerase type I 5 207 7.5E-49 T 21-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 Pfam PF01238 Phosphomannose isomerase type I 239 312 1.6E-6 T 21-04-2016 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 PIRSF PIRSF036894 2 313 4.9E-131 T 21-04-2016 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 Gene3D G3DSA:2.60.120.10 1 216 3.7E-80 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS06200 b046b26b7e19fd1b8e673681d8826810 313 PANTHER PTHR18964:SF114 1 255 3.6E-110 T 21-04-2016 HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 PANTHER PTHR10859:SF84 16 298 2.1E-54 T 21-04-2016 HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 Pfam PF00535 Glycosyl transferase family 2 12 118 1.4E-10 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 PANTHER PTHR10859 16 298 2.1E-54 T 21-04-2016 HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 SUPERFAMILY SSF53448 17 236 1.97E-18 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 Pfam PF04138 GtrA-like protein 213 330 9.1E-9 T 21-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 HSISS4_RS09520 c89a03b49223760e2203c9820c06cb3b 337 Gene3D G3DSA:3.90.550.10 2 112 9.3E-7 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 PANTHER PTHR11760:SF19 2 214 2.0E-133 T 21-04-2016 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 38.112 T 21-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 SUPERFAMILY SSF54821 106 205 1.7E-37 T 21-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 207 2.3E-92 T 21-04-2016 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 Gene3D G3DSA:3.30.1140.32 107 206 1.9E-43 T 21-04-2016 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 PANTHER PTHR11760 2 214 2.0E-133 T 21-04-2016 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 21-04-2016 IPR018280 Ribosomal protein S3, conserved site HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 Pfam PF07650 KH domain 38 109 7.0E-22 T 21-04-2016 IPR004044 K Homology domain, type 2 GO:0003723 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 SUPERFAMILY SSF54814 2 105 8.37E-38 T 21-04-2016 IPR009019 K homology domain, prokaryotic type GO:0003723 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 SMART SM00322 59 124 1.9E-9 T 21-04-2016 IPR004087 K Homology domain GO:0003676 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.5E-39 T 21-04-2016 HSISS4_RS09320 f7ba86d8c7248349cee3a800fff14208 217 Gene3D G3DSA:3.30.300.20 17 106 1.0E-33 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 Gene3D G3DSA:1.10.287.130 244 304 1.2E-12 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 SUPERFAMILY SSF55874 329 468 1.31E-34 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PANTHER PTHR24423:SF546 248 468 4.5E-66 T 21-04-2016 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PANTHER PTHR24423:SF546 2 16 4.5E-66 T 21-04-2016 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 SMART SM00388 250 317 1.8E-11 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 SMART SM00387 360 471 1.2E-31 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 Gene3D G3DSA:3.30.565.10 305 468 6.7E-37 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PANTHER PTHR24423 248 468 4.5E-66 T 21-04-2016 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PANTHER PTHR24423 2 16 4.5E-66 T 21-04-2016 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 1.0E-12 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.0E-12 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 1.0E-12 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 1.0E-12 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 SUPERFAMILY SSF47384 241 316 1.22E-11 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 Pfam PF00512 His Kinase A (phospho-acceptor) domain 252 317 4.0E-10 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS05665 b38d9538a317982ef570227034baf5c3 471 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 467 2.5E-21 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 SMART SM00354 1 71 1.2E-32 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 Pfam PF13377 Periplasmic binding protein-like domain 175 330 5.8E-33 T 21-04-2016 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 Gene3D G3DSA:3.40.50.2300 179 310 2.6E-32 T 21-04-2016 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 SUPERFAMILY SSF53822 74 330 2.36E-52 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 Gene3D G3DSA:1.10.260.40 1 50 2.0E-25 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 SUPERFAMILY SSF47413 1 59 4.34E-18 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 Gene3D G3DSA:3.40.50.2300 51 178 4.4E-29 T 21-04-2016 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 PANTHER PTHR30146:SF30 1 330 4.2E-92 T 21-04-2016 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 9.6E-5 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 9.6E-5 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.2E-20 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS04830 35b1282657d35c20b15f93579eb62583 334 PANTHER PTHR30146 1 330 4.2E-92 T 21-04-2016 HSISS4_RS08980 14674f4b386133f7d2070e134b376385 343 Pfam PF04143 Sulphur transport 21 331 5.4E-90 T 21-04-2016 IPR007272 Sulphur transport domain HSISS4_RS08980 14674f4b386133f7d2070e134b376385 343 PANTHER PTHR30574:SF1 5 340 2.0E-55 T 21-04-2016 HSISS4_RS08980 14674f4b386133f7d2070e134b376385 343 PANTHER PTHR30574 5 340 2.0E-55 T 21-04-2016 HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 375 447 3.9E-7 T 21-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 Gene3D G3DSA:2.115.10.20 43 326 1.6E-18 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 PANTHER PTHR30175 1 457 2.3E-168 T 21-04-2016 HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 22 457 1.4E-166 T 21-04-2016 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26|UniPathway: UPA00238 HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 SUPERFAMILY SSF49899 342 479 1.19E-27 T 21-04-2016 IPR013320 Concanavalin A-like lectin/glucanase domain HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 37 340 3.3E-87 T 21-04-2016 IPR013148 Glycosyl hydrolase family 32, N-terminal HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 37 50 - T 21-04-2016 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 PANTHER PTHR30175:SF8 1 457 2.3E-168 T 21-04-2016 HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 Gene3D G3DSA:2.60.120.560 327 470 6.0E-34 T 21-04-2016 IPR013189 Glycosyl hydrolase family 32, C-terminal HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 SUPERFAMILY SSF75005 27 341 2.0E-86 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS08360 e88f74baa392e629d4f0f6d0bf544090 480 SMART SM00640 37 447 2.2E-125 T 21-04-2016 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 Hamap MF_00740 Phosphopentomutase [deoB]. 4 399 54.013 T 21-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 SUPERFAMILY SSF143856 108 226 1.26E-46 T 21-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 Pfam PF01676 Metalloenzyme superfamily 6 390 1.7E-41 T 21-04-2016 IPR006124 Metalloenzyme GO:0003824|GO:0046872 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 PANTHER PTHR21110:SF0 5 403 1.4E-147 T 21-04-2016 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 PIRSF PIRSF001491 3 403 3.4E-151 T 21-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 SUPERFAMILY SSF53649 3 108 1.28E-83 T 21-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 SUPERFAMILY SSF53649 227 402 1.28E-83 T 21-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 TIGRFAM TIGR01696 deoB: phosphopentomutase 6 396 2.7E-157 T 21-04-2016 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 Gene3D G3DSA:3.30.70.1250 108 226 3.2E-51 T 21-04-2016 IPR024052 Phosphopentomutase DeoB cap domain GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180|UniPathway: UPA00087 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 PANTHER PTHR21110 5 403 1.4E-147 T 21-04-2016 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 Gene3D G3DSA:3.40.720.10 2 107 2.3E-74 T 21-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HSISS4_RS04555 94ae727ae0ba2960d116fd574aa1489d 403 Gene3D G3DSA:3.40.720.10 230 401 2.3E-74 T 21-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 SUPERFAMILY SSF143430 19 92 1.07E-19 T 21-04-2016 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 Gene3D G3DSA:3.30.70.240 19 89 8.0E-23 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 20 107 14.509 T 21-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 20 103 9.3E-14 T 21-04-2016 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 PANTHER PTHR34405:SF1 20 91 2.4E-18 T 21-04-2016 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 Pfam PF09827 CRISPR associated protein Cas2 20 89 8.9E-19 T 21-04-2016 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 HSISS4_RS05055 1b3c8525de585e4ce179976041e4de7c 109 PANTHER PTHR34405 20 91 2.4E-18 T 21-04-2016 HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 SMART SM00226 2 139 1.3E-32 T 21-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.8E-11 T 21-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 2.8E-11 T 21-04-2016 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 PANTHER PTHR11717 1 144 4.7E-35 T 21-04-2016 HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 Gene3D G3DSA:3.40.50.270 1 142 1.8E-40 T 21-04-2016 HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 137 4.2E-30 T 21-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HSISS4_RS09375 424416c77a1d5b007e3c92ead1b613fb 144 SUPERFAMILY SSF52788 1 140 1.02E-38 T 21-04-2016 IPR023485 Phosphotyrosine protein phosphatase I superfamily HSISS4_RS04815 9f1c58b6ac351beae2a00407332f9253 278 PANTHER PTHR32243 1 278 2.1E-81 T 21-04-2016 HSISS4_RS04815 9f1c58b6ac351beae2a00407332f9253 278 SUPERFAMILY SSF161098 4 278 2.99E-63 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04815 9f1c58b6ac351beae2a00407332f9253 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 270 2.0E-15 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04815 9f1c58b6ac351beae2a00407332f9253 278 PANTHER PTHR32243:SF4 1 278 2.1E-81 T 21-04-2016 HSISS4_RS04815 9f1c58b6ac351beae2a00407332f9253 278 Gene3D G3DSA:1.10.3720.10 2 266 3.5E-59 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PRINTS PR00046 Major sigma-70 factor signature 328 343 1.4E-31 T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PRINTS PR00046 Major sigma-70 factor signature 343 354 1.4E-31 T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PRINTS PR00046 Major sigma-70 factor signature 183 191 1.4E-31 T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PRINTS PR00046 Major sigma-70 factor signature 307 319 1.4E-31 T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PRINTS PR00046 Major sigma-70 factor signature 159 172 1.4E-31 T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 SUPERFAMILY SSF88659 208 282 1.2E-21 T 21-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Pfam PF03979 Sigma-70 factor, region 1.1 13 85 9.2E-7 T 21-04-2016 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 159 172 - T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 SUPERFAMILY SSF88946 96 205 3.27E-53 T 21-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 131 367 1.1E-125 T 21-04-2016 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 368 32.947 T 21-04-2016 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 328 354 - T 21-04-2016 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Pfam PF00140 Sigma-70 factor, region 1.2 97 129 3.1E-14 T 21-04-2016 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Gene3D G3DSA:1.10.601.10 30 204 1.8E-71 T 21-04-2016 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 131 356 2.2E-38 T 21-04-2016 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Gene3D G3DSA:1.10.10.10 297 368 4.2E-34 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PANTHER PTHR30603:SF0 13 368 4.0E-200 T 21-04-2016 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 PANTHER PTHR30603 13 368 4.0E-200 T 21-04-2016 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Gene3D G3DSA:1.10.10.10 208 259 7.4E-27 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Pfam PF04545 Sigma-70, region 4 303 356 2.4E-19 T 21-04-2016 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Pfam PF04539 Sigma-70 region 3 214 290 1.7E-30 T 21-04-2016 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 SUPERFAMILY SSF88659 265 366 1.08E-28 T 21-04-2016 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS07140 c77634842ac891e7119da984ecccffe0 369 Pfam PF04542 Sigma-70 region 2 135 204 5.3E-23 T 21-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 SUPERFAMILY SSF48150 3 198 6.44E-42 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 PANTHER PTHR10359 1 198 9.5E-54 T 21-04-2016 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 PIRSF PIRSF001435 1 207 2.3E-53 T 21-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 Gene3D G3DSA:1.10.340.30 21 123 3.7E-28 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 164 2.3E-7 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 Gene3D G3DSA:1.10.1670.10 124 196 1.3E-10 T 21-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 SMART SM00478 38 193 1.5E-16 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS05265 e5d21e0ba768daa5e58fd28e0bcb05da 207 PANTHER PTHR10359:SF17 1 198 9.5E-54 T 21-04-2016 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 Pfam PF00294 pfkB family carbohydrate kinase 14 277 3.2E-53 T 21-04-2016 IPR011611 Carbohydrate kinase PfkB HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 PIRSF PIRSF000535 1 303 9.3E-86 T 21-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 PANTHER PTHR10584:SF170 1 301 4.9E-108 T 21-04-2016 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 SUPERFAMILY SSF53613 1 281 6.08E-70 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 21-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 PANTHER PTHR10584 1 301 4.9E-108 T 21-04-2016 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 301 5.2E-112 T 21-04-2016 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 Gene3D G3DSA:2.20.150.10 9 35 1.1E-5 T 21-04-2016 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain KEGG: 00052+2.7.1.144|KEGG: 00710+2.7.1.14|MetaCyc: PWY-7077|MetaCyc: PWY-7395|UniPathway: UPA00704 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 Gene3D G3DSA:3.40.1190.20 36 302 9.1E-82 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 301 2.8E-110 T 21-04-2016 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 HSISS4_RS01860 c12c5afc716391a537cb6581e4546d6a 303 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 21-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.0E-6 T 21-04-2016 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 PRINTS PR00421 Thioredoxin family signature 27 36 1.0E-6 T 21-04-2016 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 PRINTS PR00421 Thioredoxin family signature 19 27 1.0E-6 T 21-04-2016 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 PIRSF PIRSF000077 1 104 2.3E-38 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 21-04-2016 IPR017937 Thioredoxin, conserved site GO:0045454 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 Gene3D G3DSA:3.40.30.10 3 103 1.9E-34 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 1.8E-34 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 PANTHER PTHR10438 1 103 2.3E-35 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 Pfam PF00085 Thioredoxin 3 101 5.6E-29 T 21-04-2016 IPR013766 Thioredoxin domain GO:0045454 HSISS4_RS08655 d024f28992988fc6ed3170e3a8119091 104 SUPERFAMILY SSF52833 3 102 1.74E-35 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 Pfam PF00849 RNA pseudouridylate synthase 61 194 2.5E-22 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 PANTHER PTHR21600 1 236 8.2E-82 T 21-04-2016 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 65 225 1.5E-47 T 21-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 SUPERFAMILY SSF55174 1 55 2.55E-16 T 21-04-2016 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 Pfam PF01479 S4 domain 1 47 2.9E-14 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 SUPERFAMILY SSF55120 45 234 8.63E-45 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 98 112 - T 21-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 SMART SM00363 1 64 8.1E-18 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 Gene3D G3DSA:3.10.290.10 1 63 1.8E-25 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS01255 c2c27721e30faf378d90f17ad7377380 241 PANTHER PTHR21600:SF2 1 236 8.2E-82 T 21-04-2016 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 SMART SM00864 14 206 3.9E-111 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PRINTS PR00423 Cell division protein FtsZ signature 99 119 3.3E-51 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PRINTS PR00423 Cell division protein FtsZ signature 213 234 3.3E-51 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PRINTS PR00423 Cell division protein FtsZ signature 190 212 3.3E-51 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PRINTS PR00423 Cell division protein FtsZ signature 127 148 3.3E-51 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 SUPERFAMILY SSF55307 205 319 4.12E-41 T 21-04-2016 IPR008280 Tubulin/FtsZ, C-terminal HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 174 4.5E-41 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 Gene3D G3DSA:3.30.1330.20 216 322 1.7E-44 T 21-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 11 333 7.0E-126 T 21-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PANTHER PTHR30314 1 377 6.8E-187 T 21-04-2016 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 21-04-2016 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 PANTHER PTHR30314:SF3 1 377 6.8E-187 T 21-04-2016 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 Pfam PF12327 FtsZ family, C-terminal domain 223 316 1.6E-28 T 21-04-2016 IPR024757 Cell division protein FtsZ, C-terminal HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 379 37.822 T 21-04-2016 IPR000158 Cell division protein FtsZ GO:0005525 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 SMART SM00865 208 325 1.8E-47 T 21-04-2016 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 Gene3D G3DSA:3.40.50.1440 15 215 1.6E-92 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS03640 ed457b484095ef30ada018540fa2fd6a 440 SUPERFAMILY SSF52490 14 209 2.35E-68 T 21-04-2016 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 21-04-2016 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 PANTHER PTHR11846 4 426 5.1E-260 T 21-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Gene3D G3DSA:1.10.300.10 100 194 5.0E-39 T 21-04-2016 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Gene3D G3DSA:3.40.440.10 195 264 1.7E-73 T 21-04-2016 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Gene3D G3DSA:3.40.440.10 1 93 1.7E-73 T 21-04-2016 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 SMART SM00788 3 422 3.1E-303 T 21-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 3.2E-190 T 21-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Gene3D G3DSA:3.90.170.10 265 423 4.6E-71 T 21-04-2016 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 430 216.261 T 21-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 SUPERFAMILY SSF52540 1 427 8.39E-179 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 Pfam PF00709 Adenylosuccinate synthetase 4 420 4.8E-184 T 21-04-2016 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS09380 5b21ff036ea32415e0ced95874ab4126 430 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 21-04-2016 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: REACT_1698|UniPathway: UPA00075 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 PANTHER PTHR40068 1 171 1.6E-68 T 21-04-2016 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 Pfam PF08279 HTH domain 5 58 1.3E-14 T 21-04-2016 IPR013196 Helix-turn-helix, type 11 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 SUPERFAMILY SSF46785 2 59 7.0E-10 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 Gene3D G3DSA:3.30.1340.20 66 170 9.7E-41 T 21-04-2016 IPR004173 3H domain GO:0036094 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 Pfam PF02829 3H domain 72 168 6.2E-32 T 21-04-2016 IPR004173 3H domain GO:0036094 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 76 169 2.0E-42 T 21-04-2016 IPR004173 3H domain GO:0036094 HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 PIRSF PIRSF037847 1 171 1.5E-65 T 21-04-2016 IPR026043 Transcription repressor NadR HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 Gene3D G3DSA:1.10.10.10 2 61 3.2E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05410 567d850634771b97d469e24f576d9aa6 171 SUPERFAMILY SSF75500 66 170 6.93E-34 T 21-04-2016 IPR004173 3H domain GO:0036094 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PANTHER PTHR22912:SF145 1 438 3.6E-199 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 Gene3D G3DSA:3.50.50.60 3 121 1.0E-25 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 Gene3D G3DSA:3.30.390.30 326 436 3.3E-33 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 388 403 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 122 131 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 323 344 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 430 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 286 293 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 257 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-51 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 SUPERFAMILY SSF51905 1 295 2.59E-48 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 295 1.5E-58 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PIRSF PIRSF000350 64 437 3.8E-71 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 433 2.3E-25 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 SUPERFAMILY SSF55424 326 436 1.68E-31 T 21-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PANTHER PTHR22912 1 438 3.6E-199 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 2.4E-30 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 2.4E-30 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 2.4E-30 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 2.4E-30 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.4E-30 T 21-04-2016 HSISS4_RS02580 8cd8c15125f76317769fb999b8f69161 438 Gene3D G3DSA:3.50.50.60 122 314 3.3E-52 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03530 be7ea95639267547aba577dfa9bad181 186 Pfam PF04011 LemA family 4 181 5.5E-69 T 21-04-2016 IPR007156 LemA HSISS4_RS03530 be7ea95639267547aba577dfa9bad181 186 SUPERFAMILY SSF140478 23 170 6.15E-54 T 21-04-2016 IPR023353 LemA-like domain HSISS4_RS03530 be7ea95639267547aba577dfa9bad181 186 PANTHER PTHR34478:SF2 1 184 5.2E-88 T 21-04-2016 HSISS4_RS03530 be7ea95639267547aba577dfa9bad181 186 Gene3D G3DSA:1.20.1440.20 11 181 4.4E-65 T 21-04-2016 IPR023353 LemA-like domain HSISS4_RS03530 be7ea95639267547aba577dfa9bad181 186 PANTHER PTHR34478 1 184 5.2E-88 T 21-04-2016 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Gene3D G3DSA:1.10.1670.10 124 210 1.6E-36 T 21-04-2016 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 21-04-2016 IPR004036 Endonuclease III-like, conserved site-2 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 4.6E-25 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 21-04-2016 IPR004035 Endonuclease III, iron-sulphur binding site HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Pfam PF00633 Helix-hairpin-helix motif 101 128 4.5E-9 T 21-04-2016 IPR000445 Helix-hairpin-helix motif GO:0003677 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 TIGRFAM TIGR01083 nth: endonuclease III 5 196 6.4E-77 T 21-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 SUPERFAMILY SSF48150 4 212 6.6E-74 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 4.3E-5 T 21-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Hamap MF_00942 Endonuclease III [nth]. 1 211 38.29 T 21-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 PIRSF PIRSF001435 4 214 3.3E-55 T 21-04-2016 IPR005759 Endonuclease III GO:0003906|GO:0006284 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 PANTHER PTHR10359 19 210 9.9E-81 T 21-04-2016 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 SMART SM00478 39 187 4.7E-59 T 21-04-2016 IPR003265 HhH-GPD domain GO:0006284 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 Gene3D G3DSA:1.10.340.30 25 123 6.1E-37 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS04045 615811f307f84f21c06957ed4337f5e9 214 SMART SM00525 188 208 3.5E-4 T 21-04-2016 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: REACT_216 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 Pfam PF14622 Ribonuclease-III-like 19 148 8.1E-36 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 SUPERFAMILY SSF54768 116 228 1.16E-25 T 21-04-2016 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 Pfam PF00035 Double-stranded RNA binding motif 161 227 3.5E-18 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 SMART SM00535 20 155 4.9E-55 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 PANTHER PTHR11207 6 227 3.8E-79 T 21-04-2016 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 Gene3D G3DSA:1.10.1520.10 6 153 2.7E-47 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 SUPERFAMILY SSF69065 6 159 1.57E-50 T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 8 227 5.0E-79 T 21-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 SMART SM00358 161 228 6.9E-25 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 Hamap MF_00104 Ribonuclease 3 [rnc]. 8 224 30.473 T 21-04-2016 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 Gene3D G3DSA:3.30.160.20 159 228 2.1E-28 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS05940 8c4151ffe7e8231171d156ed123d9431 229 ProSitePatterns PS00517 Ribonuclease III family signature. 44 52 - T 21-04-2016 IPR000999 Ribonuclease III domain GO:0003723|GO:0004525|GO:0006396 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 PANTHER PTHR11835 3 153 1.7E-207 T 21-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 PANTHER PTHR11835 177 391 1.7E-207 T 21-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 279 298 - T 21-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 PANTHER PTHR11835:SF52 3 153 1.7E-207 T 21-04-2016 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 PANTHER PTHR11835:SF52 177 391 1.7E-207 T 21-04-2016 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 SMART SM01329 19 387 5.2E-176 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 20 387 4.0E-109 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 Gene3D G3DSA:3.40.718.10 3 389 3.1E-154 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS03700 ddbaf609bd1ea640d65afa23c0c46c8c 391 SUPERFAMILY SSF53659 4 390 2.3E-135 T 21-04-2016 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PIRSF PIRSF000102 1 308 7.2E-77 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 SUPERFAMILY SSF51735 3 147 4.91E-38 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 Gene3D G3DSA:3.40.50.720 3 148 2.9E-40 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 21-04-2016 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 SUPERFAMILY SSF56327 146 302 4.61E-38 T 21-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 306 2.9E-15 T 21-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 Gene3D G3DSA:3.90.110.10 150 302 4.1E-44 T 21-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PANTHER PTHR11540:SF3 3 314 5.9E-77 T 21-04-2016 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PANTHER PTHR11540 3 314 5.9E-77 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 4 145 1.2E-21 T 21-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 3.3E-29 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PRINTS PR00086 L-lactate dehydrogenase signature 4 28 3.3E-29 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 3.3E-29 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 3.3E-29 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS03035 e414ba13cc137dcb14d53c1c8e2c9713 316 PRINTS PR00086 L-lactate dehydrogenase signature 29 53 3.3E-29 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 PANTHER PTHR30191:SF0 1 763 0.0 T 21-04-2016 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 SUPERFAMILY SSF51998 9 762 2.88E-200 T 21-04-2016 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 14 763 0.0 T 21-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 Pfam PF02901 Pyruvate formate lyase-like 30 613 2.5E-146 T 21-04-2016 IPR004184 Pyruvate formate lyase domain GO:0003824 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 Pfam PF01228 Glycine radical 642 742 3.5E-22 T 21-04-2016 IPR001150 Glycine radical domain GO:0003824|GO:0008152 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 PIRSF PIRSF000379 11 763 3.6E-287 T 21-04-2016 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493|UniPathway: UPA00920 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 PANTHER PTHR30191 1 763 0.0 T 21-04-2016 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 Gene3D G3DSA:3.20.70.20 9 762 2.0E-229 T 21-04-2016 HSISS4_RS08025 ab45aa7ee698451f8585f4b63144fbc2 770 ProSitePatterns PS00850 Glycine radical domain signature. 733 741 - T 21-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 817 906 1.2E-11 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 414 525 1.8E-14 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 832 884 8.0E-14 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 554 623 9.1E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 494 550 1.1E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 169 227 3.3E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 768 830 1.2E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 625 697 7.9E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 986 1046 3.4E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 433 491 2.9E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 699 764 4.3E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 297 362 2.6E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 531 580 2.6E-10 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 737 794 4.7E-9 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 675 729 1.7E-7 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 598 654 1.7E-7 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 616 663 2.36E-27 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 696 881 2.36E-27 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 962 1056 5.49E-23 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 159 332 1.32E-25 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 427 441 0.029 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 976 993 0.051 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 616 633 0.087 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 760 776 0.088 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 694 707 0.5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Pfam PF01473 Putative cell wall binding repeat 291 305 0.65 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 312 416 5.69E-8 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 SUPERFAMILY SSF69360 423 605 2.16E-28 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 242 301 4.1E-8 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 1000 1056 3.2E-11 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 907 994 6.3E-13 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 302 413 2.1E-11 T 21-04-2016 HSISS4_RS06545 2f55f7ee30cd59ef6872279c47560f09 1060 Gene3D G3DSA:2.10.270.10 167 241 1.6E-10 T 21-04-2016 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 293 1.1E-69 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 Gene3D G3DSA:3.40.50.1100 149 305 1.1E-69 T 21-04-2016 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 Gene3D G3DSA:3.40.50.1100 1 42 1.1E-69 T 21-04-2016 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 7 304 1.4E-129 T 21-04-2016 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 SUPERFAMILY SSF53686 1 305 2.36E-99 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 3.6E-125 T 21-04-2016 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936|UniPathway: UPA00136 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 PANTHER PTHR10314 3 305 1.7E-141 T 21-04-2016 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 21-04-2016 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 Gene3D G3DSA:3.40.50.1100 43 140 2.5E-44 T 21-04-2016 HSISS4_RS01665 94d4fd85e181c3abec6d374ecda0770d 308 PANTHER PTHR10314:SF110 3 305 1.7E-141 T 21-04-2016 HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 58 87 3.6E-10 T 21-04-2016 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 Pfam PF02627 Carboxymuconolactone decarboxylase family 51 119 1.1E-11 T 21-04-2016 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 Gene3D G3DSA:1.20.1290.10 1 88 1.2E-33 T 21-04-2016 IPR029032 AhpD-like HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 Gene3D G3DSA:1.20.1290.10 124 181 1.2E-33 T 21-04-2016 IPR029032 AhpD-like HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 PANTHER PTHR35446:SF1 1 181 1.8E-86 T 21-04-2016 HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 SUPERFAMILY SSF69118 1 180 2.36E-42 T 21-04-2016 IPR029032 AhpD-like HSISS4_RS03070 6dd7d8467871b9a19846851b97fa1796 182 PANTHER PTHR35446 1 181 1.8E-86 T 21-04-2016 HSISS4_RS06305 5a585bf8a0daa75705bc24c3809340ff 430 PANTHER PTHR33989 5 428 1.1E-30 T 21-04-2016 HSISS4_RS06305 5a585bf8a0daa75705bc24c3809340ff 430 PANTHER PTHR33989:SF4 5 428 1.1E-30 T 21-04-2016 HSISS4_RS06305 5a585bf8a0daa75705bc24c3809340ff 430 Pfam PF02378 Phosphotransferase system, EIIC 23 348 4.3E-8 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 SUPERFAMILY SSF53784 1 301 4.45E-103 T 21-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PANTHER PTHR13697:SF4 1 299 9.7E-119 T 21-04-2016 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PIRSF PIRSF000532 1 322 3.3E-112 T 21-04-2016 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 Gene3D G3DSA:3.40.50.450 1 212 3.6E-73 T 21-04-2016 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 336 45.618 T 21-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 241 263 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 2.2E-78 T 21-04-2016 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 3.6E-118 T 21-04-2016 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 PANTHER PTHR13697 1 299 9.7E-119 T 21-04-2016 HSISS4_RS04150 fb615fa8a9e30a4343fdb4f0f01a8d65 339 Pfam PF00365 Phosphofructokinase 3 277 2.5E-102 T 21-04-2016 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 Gene3D G3DSA:3.40.50.1580 1 229 1.5E-72 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 SUPERFAMILY SSF53167 1 229 7.86E-71 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 Pfam PF01048 Phosphorylase superfamily 2 226 5.2E-47 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 228 2.8E-67 T 21-04-2016 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154|UniPathway: UPA00904 HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 PANTHER PTHR21234 1 229 1.3E-50 T 21-04-2016 IPR018017 Nucleoside phosphorylase HSISS4_RS02650 8f26ec9ef1670e69a6b0ca712e96a370 230 PANTHER PTHR21234:SF16 1 229 1.3E-50 T 21-04-2016 HSISS4_RS07345 4078e9c5fc4d1bda8854dc76f75b3543 264 SUPERFAMILY SSF161098 2 259 1.68E-50 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07345 4078e9c5fc4d1bda8854dc76f75b3543 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 50 259 1.5E-10 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07345 4078e9c5fc4d1bda8854dc76f75b3543 264 PANTHER PTHR30193 7 264 4.3E-100 T 21-04-2016 HSISS4_RS07345 4078e9c5fc4d1bda8854dc76f75b3543 264 PANTHER PTHR30193:SF10 7 264 4.3E-100 T 21-04-2016 HSISS4_RS07345 4078e9c5fc4d1bda8854dc76f75b3543 264 Gene3D G3DSA:1.10.3720.10 2 259 1.2E-45 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 12 345 3.2E-119 T 21-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 PIRSF PIRSF001455 2 354 7.1E-104 T 21-04-2016 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 Pfam PF01761 3-dehydroquinate synthase 70 323 3.5E-101 T 21-04-2016 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 Gene3D G3DSA:1.20.1090.10 174 354 3.2E-56 T 21-04-2016 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 SUPERFAMILY SSF56796 1 352 2.49E-107 T 21-04-2016 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 PANTHER PTHR21090 1 355 2.1E-142 T 21-04-2016 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 38.484 T 21-04-2016 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS03015 daa3069a8ac9b9a3aa98b3463da2dc92 355 Gene3D G3DSA:3.40.50.1970 2 172 7.0E-64 T 21-04-2016 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Gene3D G3DSA:3.90.190.20 306 455 2.8E-37 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Pfam PF08245 Mur ligase middle domain 106 286 1.4E-40 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 SUPERFAMILY SSF53623 102 303 1.7E-45 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Gene3D G3DSA:3.40.1390.10 1 79 2.0E-21 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 3 454 32.076 T 21-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 SUPERFAMILY SSF63418 2 97 5.62E-23 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Gene3D G3DSA:3.40.1190.10 83 303 4.7E-57 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 PANTHER PTHR23135:SF3 14 454 1.6E-145 T 21-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Pfam PF01225 Mur ligase family, catalytic domain 26 95 3.0E-8 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 SUPERFAMILY SSF53244 306 453 1.19E-31 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 453 4.9E-112 T 21-04-2016 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 391 5.6E-10 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS07580 107084007d9d875559a10bcd440a5e00 457 PANTHER PTHR23135 14 454 1.6E-145 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Gene3D G3DSA:3.40.50.300 4 139 1.9E-27 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 SUPERFAMILY SSF48019 237 419 9.07E-67 T 21-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 SUPERFAMILY SSF52540 4 211 6.26E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Gene3D G3DSA:1.10.3710.10 331 420 7.4E-28 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Pfam PF12002 MgsA AAA+ ATPase C terminal 252 416 9.1E-62 T 21-04-2016 IPR021886 MgsA AAA+ ATPase C-terminal HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 PANTHER PTHR13779:SF7 5 404 7.2E-157 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Gene3D G3DSA:1.20.272.10 233 330 1.1E-38 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 42 144 4.5E-15 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 PANTHER PTHR13779 5 404 7.2E-157 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 SMART SM00382 38 150 3.3E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Gene3D G3DSA:1.10.8.60 140 223 4.3E-11 T 21-04-2016 HSISS4_RS09400 d7cfcfd2766d606b9885d5376598e0a8 422 Pfam PF16193 AAA C-terminal domain 173 251 7.7E-23 T 21-04-2016 IPR032423 AAA ATPase, C-terminal domain HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR00315 GTP-binding elongation factor signature 82 92 4.9E-11 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR00315 GTP-binding elongation factor signature 98 109 4.9E-11 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR00315 GTP-binding elongation factor signature 134 143 4.9E-11 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR00315 GTP-binding elongation factor signature 62 70 4.9E-11 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.9E-11 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Pfam PF16658 Class II release factor RF3, C-terminal domain 377 501 1.5E-43 T 21-04-2016 IPR032090 Peptide chain release factor 3, C-terminal HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Pfam PF03144 Elongation factor Tu domain 2 303 369 1.2E-12 T 21-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 SUPERFAMILY SSF54980 383 455 1.83E-16 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 21-04-2016 IPR031157 Tr-type G domain, conserved site HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 511 2.3E-197 T 21-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Pfam PF00009 Elongation factor Tu GTP binding domain 9 265 2.3E-50 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 120 143 1.1E-8 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 239 261 1.1E-8 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Gene3D G3DSA:3.40.50.300 4 270 1.2E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 SUPERFAMILY SSF50447 249 379 8.84E-29 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 SUPERFAMILY SSF52540 6 265 4.36E-86 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Gene3D G3DSA:3.30.70.870 384 454 1.2E-14 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 514 49.844 T 21-04-2016 IPR004548 Peptide chain release factor 3 GO:0005525|GO:0005737|GO:0006415|GO:0016149 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PANTHER PTHR23115:SF69 1 181 1.1E-230 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PANTHER PTHR23115:SF69 239 456 1.1E-230 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PANTHER PTHR23115 1 181 1.1E-230 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 PANTHER PTHR23115 239 456 1.1E-230 T 21-04-2016 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 157 2.5E-20 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS07570 30a9850ccc62481b62c432be3a3aeefe 514 Gene3D G3DSA:2.40.30.10 282 383 7.6E-26 T 21-04-2016 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Gene3D G3DSA:2.30.24.10 1 53 1.6E-24 T 21-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 SUPERFAMILY SSF63520 172 273 6.15E-26 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Pfam PF00874 PRD domain 184 272 1.1E-18 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Pfam PF00874 PRD domain 76 162 3.6E-21 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Gene3D G3DSA:1.10.1790.10 170 274 3.0E-30 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Gene3D G3DSA:1.10.1790.10 70 165 7.0E-26 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 PANTHER PTHR30185:SF2 1 278 1.4E-100 T 21-04-2016 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 SUPERFAMILY SSF50151 1 53 6.8E-19 T 21-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 SMART SM01061 1 58 4.0E-26 T 21-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 PANTHER PTHR30185 1 278 1.4E-100 T 21-04-2016 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 Pfam PF03123 CAT RNA binding domain 1 53 9.3E-23 T 21-04-2016 IPR004341 CAT RNA-binding domain GO:0003723 HSISS4_RS02900 1b59fb104a3c08f1d3086176c78e6f4a 279 SUPERFAMILY SSF63520 56 165 8.76E-26 T 21-04-2016 IPR011608 PRD domain GO:0006355 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 Pfam PF01979 Amidohydrolase family 50 376 1.6E-23 T 21-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 Gene3D G3DSA:2.30.40.10 13 53 1.1E-6 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 Gene3D G3DSA:2.30.40.10 350 366 1.1E-6 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 PANTHER PTHR11113 3 378 8.7E-134 T 21-04-2016 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 SUPERFAMILY SSF51338 350 379 1.27E-10 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 SUPERFAMILY SSF51338 1 52 1.27E-10 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 SUPERFAMILY SSF51556 53 350 1.7E-96 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 Gene3D G3DSA:3.20.20.140 54 349 8.8E-103 T 21-04-2016 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 34 376 1.0E-87 T 21-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 PANTHER PTHR11113:SF7 3 378 8.7E-134 T 21-04-2016 HSISS4_RS02365 fd1fe845c162be540a4dd124fe4939b9 382 PIRSF PIRSF038994 1 382 9.0E-116 T 21-04-2016 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395 HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 Pfam PF06969 HemN C-terminal domain 300 365 2.2E-20 T 21-04-2016 IPR010723 HemN, C-terminal HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 PANTHER PTHR13932:SF5 1 377 4.9E-154 T 21-04-2016 HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 SUPERFAMILY SSF102114 3 375 3.92E-119 T 21-04-2016 HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 7 365 1.0E-118 T 21-04-2016 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00071+1.3.99.-|KEGG: 00280+1.3.99.-|KEGG: 00281+1.3.99.-|KEGG: 00362+1.3.99.-|KEGG: 00626+1.3.99.-|KEGG: 00930+1.3.99.- HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 Gene3D G3DSA:3.80.30.20 4 237 2.5E-40 T 21-04-2016 IPR023404 Radical SAM, alpha/beta horseshoe HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 Pfam PF04055 Radical SAM superfamily 10 174 1.4E-22 T 21-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 SMART SM00729 5 221 1.2E-58 T 21-04-2016 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 HSISS4_RS03845 09f185c4bf9d9cf2002d43eb8b300b72 378 PANTHER PTHR13932 1 377 4.9E-154 T 21-04-2016 HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 PANTHER PTHR30195 7 897 1.7E-118 T 21-04-2016 HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 Pfam PF04851 Type III restriction enzyme, res subunit 260 427 4.2E-31 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 204 2.3E-21 T 21-04-2016 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 PANTHER PTHR30195:SF16 7 897 1.7E-118 T 21-04-2016 HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 SUPERFAMILY SSF52540 281 318 4.32E-6 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 SUPERFAMILY SSF52540 597 691 4.32E-6 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 Gene3D G3DSA:3.40.50.300 254 441 1.9E-23 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 SMART SM00487 256 457 1.3E-13 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 Pfam PF12008 Type I restriction and modification enzyme - subunit R C terminal 712 983 3.7E-30 T 21-04-2016 IPR022625 Type-1 restriction enzyme R protein, C-terminal HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 SUPERFAMILY SSF52540 253 498 4.38E-28 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03475 a2749ba4b238cb4b61db18a0af7383a4 996 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 706 1.7E-97 T 21-04-2016 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 HSISS4_RS04805 374387d23789f0c44cd16a08f07eeeb8 61 Pfam PF02416 mttA/Hcf106 family 7 57 3.8E-16 T 21-04-2016 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 HSISS4_RS04805 374387d23789f0c44cd16a08f07eeeb8 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 4 24 1.3E-5 T 21-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 HSISS4_RS04805 374387d23789f0c44cd16a08f07eeeb8 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 43 61 1.3E-5 T 21-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 HSISS4_RS04805 374387d23789f0c44cd16a08f07eeeb8 61 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 24 43 1.3E-5 T 21-04-2016 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 139 202 3.1E-4 T 21-04-2016 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 Gene3D G3DSA:3.30.360.10 143 318 5.1E-54 T 21-04-2016 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 SUPERFAMILY SSF55347 131 290 6.05E-16 T 21-04-2016 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 PANTHER PTHR22604 1 316 3.2E-61 T 21-04-2016 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 Gene3D G3DSA:3.40.50.720 1 142 4.0E-43 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.0E-25 T 21-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 SUPERFAMILY SSF51735 2 153 3.94E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02825 59913cbb6c09fa0922223edf4122f896 320 PANTHER PTHR22604:SF76 1 316 3.2E-61 T 21-04-2016 HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 Pfam PF07972 NrdI Flavodoxin like 6 138 1.9E-41 T 21-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 SUPERFAMILY SSF52218 1 142 1.49E-20 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 PANTHER PTHR37297 3 148 3.0E-36 T 21-04-2016 HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 PIRSF PIRSF005087 2 152 4.8E-41 T 21-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 Gene3D G3DSA:3.40.50.360 5 146 6.5E-44 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 PANTHER PTHR37297:SF1 3 148 3.0E-36 T 21-04-2016 HSISS4_RS00775 d4a4f315856a1e5eef0663365caa77d8 152 TIGRFAM TIGR00333 nrdI: nrdI protein 7 144 1.9E-22 T 21-04-2016 IPR004465 Ribonucleotide reductase Class Ib, NrdI HSISS4_RS09665 b109c47461504054398ecd8a3c1e4f8b 285 Pfam PF13464 Domain of unknown function (DUF4115) 211 274 1.4E-6 T 21-04-2016 IPR025194 Domain of unknown function DUF4115 HSISS4_RS09665 b109c47461504054398ecd8a3c1e4f8b 285 Pfam PF13413 Helix-turn-helix domain 9 68 1.0E-11 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS09665 b109c47461504054398ecd8a3c1e4f8b 285 Gene3D G3DSA:1.10.260.40 6 98 5.1E-7 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 Gene3D G3DSA:3.40.50.300 1 208 2.9E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 Pfam PF00005 ABC transporter 20 155 1.5E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 PANTHER PTHR24220 3 207 6.3E-106 T 21-04-2016 HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 SMART SM00382 28 210 1.5E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 SUPERFAMILY SSF52540 1 207 3.28E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06425 e367ef201530891473f44b17a5883b6d 210 PANTHER PTHR24220:SF587 3 207 6.3E-106 T 21-04-2016 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 SUPERFAMILY SSF118352 231 288 1.09E-19 T 21-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 PANTHER PTHR30111 1 288 3.7E-84 T 21-04-2016 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 PANTHER PTHR30111:SF1 1 288 3.7E-84 T 21-04-2016 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 Gene3D G3DSA:3.90.1280.10 232 287 2.0E-24 T 21-04-2016 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 Gene3D G3DSA:3.55.30.10 1 231 9.9E-74 T 21-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 PIRSF PIRSF005261 1 288 3.9E-74 T 21-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 Pfam PF01430 Hsp33 protein 2 278 4.9E-80 T 21-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 SUPERFAMILY SSF64397 1 239 4.97E-65 T 21-04-2016 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 HSISS4_RS00890 beb35d3cc7e8f0b156e174ee6f9cc5b7 288 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 288 35.698 T 21-04-2016 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 PANTHER PTHR24220:SF428 6 270 7.8E-103 T 21-04-2016 HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 SMART SM00382 29 207 4.7E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 PANTHER PTHR24220 6 270 7.8E-103 T 21-04-2016 HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 Gene3D G3DSA:3.40.50.300 2 228 2.0E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 Pfam PF00005 ABC transporter 21 160 1.8E-29 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06025 8859a2f2a1453c1c3e31a6a5d6cb8c31 278 SUPERFAMILY SSF52540 6 223 8.67E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 PANTHER PTHR10000 1 279 5.8E-54 T 21-04-2016 HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 272 2.8E-54 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 272 7.9E-55 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 Gene3D G3DSA:3.40.50.1000 191 273 1.5E-45 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 Gene3D G3DSA:3.40.50.1000 1 82 1.5E-45 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 SUPERFAMILY SSF56784 1 278 1.94E-56 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 90 1.3E-11 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS03455 6026d84ceb4911a818ad94bdffb68f96 280 PANTHER PTHR10000:SF8 1 279 5.8E-54 T 21-04-2016 HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 SUPERFAMILY SSF52540 183 439 2.74E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 PANTHER PTHR30153 3 452 3.5E-192 T 21-04-2016 HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 2.1E-33 T 21-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 SUPERFAMILY SSF48024 8 119 4.71E-36 T 21-04-2016 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 Pfam PF03796 DnaB-like helicase C terminal domain 185 445 7.2E-109 T 21-04-2016 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 Gene3D G3DSA:3.40.50.300 171 448 9.1E-103 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 Gene3D G3DSA:1.10.860.10 10 112 2.4E-35 T 21-04-2016 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal HSISS4_RS09600 0ed1a25d06c3f3bc90efe9cc36721cb7 453 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 448 6.1E-169 T 21-04-2016 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 Pfam PF04452 RNA methyltransferase 16 241 7.3E-69 T 21-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 PANTHER PTHR30027:SF3 1 247 2.8E-73 T 21-04-2016 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 6 244 1.7E-50 T 21-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 SUPERFAMILY SSF75217 68 244 1.61E-50 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 PANTHER PTHR30027 1 247 2.8E-73 T 21-04-2016 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 Gene3D G3DSA:3.40.1280.10 1 244 6.5E-70 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 PIRSF PIRSF015601 1 245 1.0E-48 T 21-04-2016 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS00765 81f8e1730595ac5e6da3ceaf8edc0e53 247 SUPERFAMILY SSF88697 3 61 4.22E-11 T 21-04-2016 IPR015947 PUA-like domain HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 PANTHER PTHR26402 1 216 2.1E-70 T 21-04-2016 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 Gene3D G3DSA:1.10.10.10 121 216 2.9E-26 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 SMART SM00862 142 214 6.6E-22 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 SUPERFAMILY SSF52172 1 173 1.85E-38 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 Pfam PF00072 Response regulator receiver domain 3 111 3.5E-25 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 PANTHER PTHR26402:SF511 1 216 2.1E-70 T 21-04-2016 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 Gene3D G3DSA:3.40.50.2300 1 120 7.3E-35 T 21-04-2016 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 214 3.3E-20 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06415 0c92c3a4640f6723c9f2a8e47c20dff5 217 SMART SM00448 1 111 2.2E-37 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 Gene3D G3DSA:3.40.50.300 2 221 8.8E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 SUPERFAMILY SSF52540 4 219 3.04E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 Pfam PF00005 ABC transporter 20 155 2.0E-22 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 PANTHER PTHR24220 6 227 7.6E-77 T 21-04-2016 HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 PANTHER PTHR24220:SF530 6 227 7.6E-77 T 21-04-2016 HSISS4_RS06970 9667a60fc68a2cbec54de5cfa7af5932 232 SMART SM00382 29 204 2.4E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 606 618 2.7E-19 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 240 254 2.7E-19 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 391 405 2.7E-19 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 601 2.7E-19 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF55008 1 70 9.82E-12 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF81665 87 147 7.19E-13 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF81665 291 385 7.19E-13 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PANTHER PTHR24093 1 688 1.8E-255 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 141 685 1.1E-163 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Pfam PF00403 Heavy-metal-associated domain 7 60 1.5E-9 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF81653 194 290 8.76E-20 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 162 661 1.1E-66 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00941 Cadmium-transporting ATPase signature 175 195 1.2E-7 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00941 Cadmium-transporting ATPase signature 5 14 1.2E-7 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00941 Cadmium-transporting ATPase signature 16 37 1.2E-7 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PRINTS PR00941 Cadmium-transporting ATPase signature 275 289 1.2E-7 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 21-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 141 687 8.2E-149 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Gene3D G3DSA:2.70.150.10 141 291 8.3E-21 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Pfam PF00122 E1-E2 ATPase 162 382 9.6E-56 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Pfam PF00702 haloacid dehalogenase-like hydrolase 388 596 3.4E-32 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Gene3D G3DSA:3.40.50.1000 508 651 4.3E-43 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Gene3D G3DSA:3.40.50.1000 365 407 4.3E-43 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 PANTHER PTHR24093:SF210 1 688 1.8E-255 T 21-04-2016 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 393 399 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF56784 446 683 8.76E-51 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 SUPERFAMILY SSF56784 389 409 8.76E-51 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Gene3D G3DSA:3.40.1110.10 409 507 1.4E-8 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS03130 742fc7abc59d7ee6f941657fa627a03b 695 Gene3D G3DSA:3.30.70.100 1 71 3.1E-14 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:3.90.1100.10 21 140 1.3E-146 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:3.90.1100.10 405 551 1.3E-146 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:3.90.1100.10 621 675 1.3E-146 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF04563 RNA polymerase beta subunit 28 460 1.1E-28 T 21-04-2016 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 ProSitePatterns PS01166 RNA polymerases beta chain signature. 918 930 - T 21-04-2016 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF00562 RNA polymerase Rpb2, domain 6 679 1065 1.1E-162 T 21-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 PANTHER PTHR20856 2 291 0.0 T 21-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 PANTHER PTHR20856 383 1147 0.0 T 21-04-2016 IPR015712 DNA-directed RNA polymerase, subunit 2 GO:0003899|GO:0006351|GO:0032549 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:2.40.50.150 782 914 2.4E-57 T 21-04-2016 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF10385 RNA polymerase beta subunit external 1 domain 551 618 1.4E-22 T 21-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF04565 RNA polymerase Rpb2, domain 3 473 538 1.3E-28 T 21-04-2016 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:3.90.1110.10 142 300 1.8E-65 T 21-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:3.90.1110.10 380 404 1.8E-65 T 21-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:2.40.50.100 677 747 4.9E-27 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 215 892 8.4E-292 T 21-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 PANTHER PTHR20856:SF20 2 291 0.0 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 PANTHER PTHR20856:SF20 383 1147 0.0 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 369 414 8.3E-8 T 21-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 288 1.5E-22 T 21-04-2016 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:2.40.270.10 915 1043 5.5E-80 T 21-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:2.40.270.10 748 775 5.5E-80 T 21-04-2016 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1143 12.299 T 21-04-2016 IPR010243 DNA-directed RNA polymerase, beta subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 SUPERFAMILY SSF64484 382 1150 0.0 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 SUPERFAMILY SSF64484 14 291 0.0 T 21-04-2016 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Gene3D G3DSA:2.30.150.10 552 618 2.3E-24 T 21-04-2016 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 HSISS4_RS09090 bf71e2fe5ba99d315e8346ddd211d41b 1193 Pfam PF04560 RNA polymerase Rpb2, domain 7 1067 1141 9.3E-26 T 21-04-2016 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: REACT_1788 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 441 537 1.2E-15 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 490 507 - T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 SUPERFAMILY SSF51261 580 722 4.36E-52 T 21-04-2016 IPR011055 Duplicated hybrid motif HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 644 656 - T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 PANTHER PTHR30009:SF8 10 563 0.0 T 21-04-2016 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 Pfam PF02378 Phosphotransferase system, EIIC 17 380 4.2E-50 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 583 702 5.5E-42 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 Gene3D G3DSA:3.30.1360.60 475 552 4.4E-25 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 Pfam PF00367 phosphotransferase system, EIIB 480 511 7.7E-15 T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 581 704 2.1E-50 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 Gene3D G3DSA:2.70.70.10 579 726 2.2E-59 T 21-04-2016 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 TIGRFAM TIGR02003 PTS-II-BC-unk1: PTS system, IIBC component 8 553 5.7E-283 T 21-04-2016 IPR011300 Phosphotransferase system, IIBC component KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 SUPERFAMILY SSF55604 478 551 2.22E-19 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS00920 857962431fe2668f83e6aea346672218 728 PANTHER PTHR30009 10 563 0.0 T 21-04-2016 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 Gene3D G3DSA:1.10.10.10 14 141 9.2E-40 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 SUPERFAMILY SSF46785 14 140 1.17E-33 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 SMART SM00347 29 129 5.4E-28 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 Pfam PF01047 MarR family 36 93 2.1E-13 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00450 d8a91de2032e465248de57f78f9ce6f2 142 PANTHER PTHR33164 13 139 8.8E-29 T 21-04-2016 HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 Gene3D G3DSA:3.90.230.10 126 351 1.4E-81 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 PANTHER PTHR10804 1 352 1.5E-94 T 21-04-2016 HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 SUPERFAMILY SSF53092 1 126 1.55E-28 T 21-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 PANTHER PTHR10804:SF86 1 352 1.5E-94 T 21-04-2016 HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 Gene3D G3DSA:3.40.350.10 1 125 6.8E-30 T 21-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 7.9E-26 T 21-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 SUPERFAMILY SSF55920 126 353 2.22E-76 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 Pfam PF00557 Metallopeptidase family M24 135 337 1.6E-62 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS08390 d708d3022c4f71484fb49619bf0b19ab 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 284 296 - T 21-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 SUPERFAMILY SSF81301 13 204 6.05E-48 T 21-04-2016 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 Gene3D G3DSA:3.30.460.10 11 153 3.2E-32 T 21-04-2016 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 PANTHER PTHR21262 47 204 8.0E-28 T 21-04-2016 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 Gene3D G3DSA:1.10.287.860 156 204 2.7E-21 T 21-04-2016 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 PANTHER PTHR21262:SF11 47 204 8.0E-28 T 21-04-2016 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 Pfam PF04607 Region found in RelA / SpoT proteins 46 170 6.5E-33 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS02000 45d732ef16fcda7dece305e190dac690 207 SMART SM00954 46 173 1.1E-37 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 9 645 50.167 T 21-04-2016 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Pfam PF01751 Toprim domain 430 540 1.9E-17 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 SMART SM00387 36 182 4.4E-26 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 228 250 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 383 403 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 369 383 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 319 335 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 600 612 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 11 21 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 202 215 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 187 202 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 616 632 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR01159 DNA gyrase subunit B signature 481 490 2.8E-51 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 636 3.5E-28 T 21-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 SMART SM00433 40 640 0.0 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 21-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Gene3D G3DSA:3.30.565.10 11 220 5.5E-86 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 515 532 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 40 55 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 579 595 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 75 88 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 535 547 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 275 288 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 117 131 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 431 445 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PRINTS PR00418 DNA topoisomerase II family signature 497 513 5.0E-71 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PANTHER PTHR10169 9 639 0.0 T 21-04-2016 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Pfam PF00204 DNA gyrase B 229 399 4.3E-57 T 21-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 PANTHER PTHR10169:SF44 9 639 0.0 T 21-04-2016 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Gene3D G3DSA:3.40.50.670 416 627 1.2E-86 T 21-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 9 646 0.0 T 21-04-2016 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 37 180 1.5E-22 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 SUPERFAMILY SSF55874 10 219 8.77E-68 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 SUPERFAMILY SSF54211 229 399 3.03E-53 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 SUPERFAMILY SSF56719 405 643 6.8E-87 T 21-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HSISS4_RS02760 1b2fe620cd631884d21f4c4f40c0ee68 649 Gene3D G3DSA:3.30.230.10 228 399 3.4E-64 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS00050 88cb6a6c3d24250fe7fdfacc62e449d6 430 Pfam PF13354 Beta-lactamase enzyme family 215 407 1.2E-35 T 21-04-2016 HSISS4_RS00050 88cb6a6c3d24250fe7fdfacc62e449d6 430 Gene3D G3DSA:3.40.710.10 187 429 4.2E-48 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00050 88cb6a6c3d24250fe7fdfacc62e449d6 430 SUPERFAMILY SSF56601 194 427 3.83E-33 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00050 88cb6a6c3d24250fe7fdfacc62e449d6 430 SUPERFAMILY SSF82057 118 186 1.5E-5 T 21-04-2016 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 Gene3D G3DSA:1.10.10.10 1 67 1.4E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 PANTHER PTHR11751:SF294 85 356 1.7E-57 T 21-04-2016 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 PANTHER PTHR11751 85 356 1.7E-57 T 21-04-2016 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 SUPERFAMILY SSF46785 1 70 9.44E-16 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 SUPERFAMILY SSF53383 53 372 2.69E-51 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 2.4E-11 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 Pfam PF00155 Aminotransferase class I and II 75 297 1.3E-12 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 SMART SM00345 7 66 3.9E-11 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS05895 c5a9f3f5f522b744a2f0440c315d0683 421 Gene3D G3DSA:3.40.640.10 103 325 2.0E-55 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Gene3D G3DSA:3.40.50.670 415 633 3.5E-89 T 21-04-2016 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Gene3D G3DSA:3.30.565.10 15 227 7.5E-92 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 SMART SM00387 40 184 1.6E-21 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Gene3D G3DSA:3.30.230.10 231 403 3.2E-76 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 SUPERFAMILY SSF56719 405 642 1.26E-84 T 21-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 579 640 9.6E-30 T 21-04-2016 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Pfam PF01751 Toprim domain 430 541 1.5E-17 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 15 649 8.5E-298 T 21-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 385 405 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 371 385 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 205 218 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 620 636 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 190 205 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 231 253 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 481 490 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 15 25 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 604 616 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR01159 DNA gyrase subunit B signature 323 339 7.7E-77 T 21-04-2016 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 SMART SM00433 44 644 0.0 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 497 513 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 431 445 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 535 547 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 515 532 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 583 599 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 79 92 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 122 136 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 279 292 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PRINTS PR00418 DNA topoisomerase II family signature 44 59 3.4E-68 T 21-04-2016 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 PANTHER PTHR10169 1 643 9.1E-303 T 21-04-2016 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Pfam PF00204 DNA gyrase B 232 401 2.2E-66 T 21-04-2016 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 ProSitePatterns PS00177 DNA topoisomerase II signature. 433 441 - T 21-04-2016 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 SUPERFAMILY SSF54211 232 402 1.84E-63 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 SUPERFAMILY SSF55874 14 227 7.66E-74 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 42 183 4.2E-23 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07270 bde0e9d5f0c045b0365c5e7a4892849d 650 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 12 650 89.82 T 21-04-2016 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 SUPERFAMILY SSF53659 5 324 1.03E-99 T 21-04-2016 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 PIRSF PIRSF000428 1 327 6.1E-110 T 21-04-2016 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 Gene3D G3DSA:3.40.50.10750 136 297 3.2E-70 T 21-04-2016 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 321 1.1E-120 T 21-04-2016 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 PANTHER PTHR23406 1 326 3.4E-51 T 21-04-2016 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 Pfam PF01515 Phosphate acetyl/butaryl transferase 7 321 4.2E-124 T 21-04-2016 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637|UniPathway: UPA00340 HSISS4_RS07010 47c4460d10e5056089630abae1e207e6 327 PANTHER PTHR23406:SF3 1 326 3.4E-51 T 21-04-2016 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-10 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-10 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-10 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 Pfam PF03466 LysR substrate binding domain 103 294 1.0E-15 T 21-04-2016 IPR005119 LysR, substrate-binding HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 Gene3D G3DSA:1.10.10.10 1 79 3.0E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 2.9E-21 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 SUPERFAMILY SSF46785 1 92 2.08E-22 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 PANTHER PTHR30126 1 297 8.6E-45 T 21-04-2016 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 SUPERFAMILY SSF53850 98 294 2.35E-17 T 21-04-2016 HSISS4_RS02070 a54ed84b145bedbbc3d466672f0e520d 298 Gene3D G3DSA:3.40.190.10 105 205 4.0E-9 T 21-04-2016 HSISS4_RS04020 5d76727430faa3abffaf970b51d2bb8a 134 PANTHER PTHR23091 10 126 2.2E-13 T 21-04-2016 HSISS4_RS04020 5d76727430faa3abffaf970b51d2bb8a 134 PANTHER PTHR23091:SF228 10 126 2.2E-13 T 21-04-2016 HSISS4_RS04020 5d76727430faa3abffaf970b51d2bb8a 134 Pfam PF13673 Acetyltransferase (GNAT) domain 33 125 2.1E-13 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS04020 5d76727430faa3abffaf970b51d2bb8a 134 Gene3D G3DSA:3.40.630.30 10 129 9.0E-29 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04020 5d76727430faa3abffaf970b51d2bb8a 134 SUPERFAMILY SSF55729 10 126 1.5E-23 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04340 0925d5baf75efeb7d7000cce194a6dbb 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 219 4.1E-21 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04340 0925d5baf75efeb7d7000cce194a6dbb 232 Gene3D G3DSA:1.10.3720.10 21 224 3.3E-45 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04340 0925d5baf75efeb7d7000cce194a6dbb 232 PANTHER PTHR30614 16 223 8.6E-67 T 21-04-2016 HSISS4_RS04340 0925d5baf75efeb7d7000cce194a6dbb 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 122 1.6E-22 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS04340 0925d5baf75efeb7d7000cce194a6dbb 232 SUPERFAMILY SSF161098 25 217 1.7E-40 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 SMART SM00382 30 204 1.6E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 Gene3D G3DSA:3.40.50.300 2 222 9.4E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 PANTHER PTHR24220:SF165 7 223 3.5E-70 T 21-04-2016 HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 SUPERFAMILY SSF52540 3 221 5.53E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 Pfam PF00005 ABC transporter 21 156 8.0E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06115 66c1895d896491fe25a37aef5b7fa64d 293 PANTHER PTHR24220 7 223 3.5E-70 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 332 58.677 T 21-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 307 4.0E-104 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 Gene3D G3DSA:3.30.420.40 5 161 2.1E-48 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PANTHER PTHR11735 1 310 2.2E-143 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 312 1.4E-128 T 21-04-2016 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 156 177 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 100 119 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 79 99 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 133 145 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 266 275 4.0E-48 T 21-04-2016 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 PANTHER PTHR11735:SF6 1 310 2.2E-143 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 Gene3D G3DSA:3.30.420.40 250 288 6.7E-4 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 Pfam PF00814 Glycoprotease family 26 307 6.0E-103 T 21-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 SUPERFAMILY SSF53067 5 309 1.55E-40 T 21-04-2016 HSISS4_RS08525 e3aced1420f4204cf2aee10d51c6b7cf 337 ProSitePatterns PS01016 Glycoprotease family signature. 99 119 - T 21-04-2016 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS04175 2867ef2f50cc0ae8fa8c1bdd73bdf2c4 289 Pfam PF02653 Branched-chain amino acid transport system / permease component 2 271 3.8E-31 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS04175 2867ef2f50cc0ae8fa8c1bdd73bdf2c4 289 PANTHER PTHR32196 2 280 3.8E-73 T 21-04-2016 HSISS4_RS04175 2867ef2f50cc0ae8fa8c1bdd73bdf2c4 289 PANTHER PTHR32196:SF27 2 280 3.8E-73 T 21-04-2016 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 5 405 5.7E-194 T 21-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 PANTHER PTHR11262:SF4 4 405 1.6E-231 T 21-04-2016 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Pfam PF06689 ClpX C4-type zinc finger 11 47 4.8E-17 T 21-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 304 7.2E-49 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 SUPERFAMILY SSF57716 10 45 9.69E-11 T 21-04-2016 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 PANTHER PTHR11262 4 405 1.6E-231 T 21-04-2016 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 SMART SM00994 9 48 1.4E-20 T 21-04-2016 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Gene3D G3DSA:3.40.50.300 288 304 6.2E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Gene3D G3DSA:3.40.50.300 61 251 6.2E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 SMART SM00382 109 259 1.6E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 389 5.7E-19 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Gene3D G3DSA:1.10.8.60 310 406 5.4E-39 T 21-04-2016 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 SUPERFAMILY SSF52540 59 395 6.5E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 3 408 51.249 T 21-04-2016 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 HSISS4_RS02725 3c793b2767aff76dde21201122128008 408 SMART SM01086 311 405 3.3E-34 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 Gene3D G3DSA:3.40.50.1360 86 182 1.3E-7 T 21-04-2016 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 8 93 9.3E-31 T 21-04-2016 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 Gene3D G3DSA:3.40.50.2000 8 85 9.8E-32 T 21-04-2016 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 Pfam PF00455 DeoR C terminal sensor domain 79 193 8.8E-31 T 21-04-2016 IPR014036 DeoR C-terminal sensor domain HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 SMART SM01134 72 196 2.9E-28 T 21-04-2016 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 PANTHER PTHR18964 10 87 1.9E-40 T 21-04-2016 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 SUPERFAMILY SSF53756 8 90 8.79E-29 T 21-04-2016 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 PANTHER PTHR18964:SF2 10 87 1.9E-40 T 21-04-2016 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 KEGG: 00520+5.1.3.14|MetaCyc: PWY-7335 HSISS4_RS09505 80b0cbbaa8242a77086236556ce23b80 202 SUPERFAMILY SSF100950 77 193 2.2E-19 T 21-04-2016 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 SUPERFAMILY SSF52540 4 244 5.91E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Pfam PF12848 ABC transporter 229 314 3.0E-20 T 21-04-2016 IPR032781 ABC-transporter extension domain HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 SMART SM00382 28 238 1.5E-8 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 SMART SM00382 349 512 9.8E-8 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Gene3D G3DSA:3.40.50.300 327 508 3.6E-33 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Pfam PF00005 ABC transporter 343 468 2.0E-19 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Pfam PF00005 ABC transporter 20 190 2.5E-25 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 SUPERFAMILY SSF52540 305 504 9.61E-35 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Gene3D G3DSA:3.40.50.300 123 279 6.0E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 Gene3D G3DSA:3.40.50.300 2 90 6.0E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 PANTHER PTHR19211 1 510 2.2E-300 T 21-04-2016 HSISS4_RS05870 ac52ed4dc8fd91d6756e65ceb888fe2c 512 PANTHER PTHR19211:SF65 1 510 2.2E-300 T 21-04-2016 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 SUPERFAMILY SSF56059 101 296 2.05E-54 T 21-04-2016 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 SUPERFAMILY SSF52440 4 86 6.33E-25 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 351 40.188 T 21-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 PANTHER PTHR11609:SF5 1 356 1.2E-127 T 21-04-2016 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 Pfam PF02222 ATP-grasp domain 112 276 3.1E-46 T 21-04-2016 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type UniPathway: UPA00074 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 Gene3D G3DSA:3.30.470.20 179 354 2.1E-62 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 Gene3D G3DSA:3.40.50.20 3 109 1.1E-34 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 Gene3D G3DSA:3.30.1490.20 117 178 3.3E-18 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 PANTHER PTHR11609 1 356 1.2E-127 T 21-04-2016 HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 SUPERFAMILY SSF51246 300 355 1.8E-15 T 21-04-2016 IPR011054 Rudiment single hybrid motif HSISS4_RS00265 3f92bd9289da3f934c46d125d4ad2c1b 363 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 6 354 8.3E-108 T 21-04-2016 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 HSISS4_RS04490 ed8c099ab997f304868dc4a410f499a2 218 SMART SM00257 171 218 0.0068 T 21-04-2016 IPR018392 LysM domain HSISS4_RS04490 ed8c099ab997f304868dc4a410f499a2 218 Gene3D G3DSA:3.10.350.10 173 200 5.2E-5 T 21-04-2016 IPR018392 LysM domain HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 114 5.3E-36 T 21-04-2016 IPR006504 Transcriptional regulator Spx/MgsR HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 PANTHER PTHR30041 1 134 7.0E-70 T 21-04-2016 HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 36.967 T 21-04-2016 IPR023731 Regulatory protein Spx GO:0045892 HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 Pfam PF03960 ArsC family 22 113 4.6E-26 T 21-04-2016 IPR006660 Arsenate reductase-like HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 SUPERFAMILY SSF52833 1 126 1.71E-39 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 Gene3D G3DSA:3.40.30.10 1 125 1.8E-37 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS04915 f39a717b94998f48ac90931722375b37 137 PANTHER PTHR30041:SF5 1 134 7.0E-70 T 21-04-2016 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 SUPERFAMILY SSF55831 3 285 1.26E-73 T 21-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PRINTS PR00108 Thymidylate synthase family signature 178 204 5.1E-13 T 21-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PRINTS PR00108 Thymidylate synthase family signature 129 148 5.1E-13 T 21-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PRINTS PR00108 Thymidylate synthase family signature 216 233 5.1E-13 T 21-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PRINTS PR00108 Thymidylate synthase family signature 54 75 5.1E-13 T 21-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 Gene3D G3DSA:3.30.572.10 5 286 3.4E-65 T 21-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PANTHER PTHR11548 12 286 1.3E-121 T 21-04-2016 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 Hamap MF_00008 Thymidylate synthase [thyA]. 5 286 30.966 T 21-04-2016 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 ProSitePatterns PS00091 Thymidylate synthase active site. 140 169 - T 21-04-2016 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 PANTHER PTHR11548:SF1 12 286 1.3E-121 T 21-04-2016 HSISS4_RS02715 b6f9d3cc9c2ac93c396bd9332ec660b0 286 Pfam PF00303 Thymidylate synthase 8 286 3.1E-63 T 21-04-2016 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|UniPathway: UPA00575 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 Gene3D G3DSA:2.70.70.10 480 631 2.6E-59 T 21-04-2016 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 Pfam PF02378 Phosphotransferase system, EIIC 111 392 8.2E-30 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 Pfam PF00367 phosphotransferase system, EIIB 10 42 2.6E-14 T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 TIGRFAM TIGR01995 PTS-II-ABC-beta: PTS system, beta-glucoside-specific IIABC component 4 631 4.9E-199 T 21-04-2016 IPR011297 Phosphotransferase system, beta-glucoside-specific IIABC component GO:0005886|GO:0008982|GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 PANTHER PTHR30175:SF1 4 582 6.0E-166 T 21-04-2016 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 486 610 3.5E-49 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 549 561 - T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 SUPERFAMILY SSF51261 481 631 3.14E-53 T 21-04-2016 IPR011055 Duplicated hybrid motif HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 Gene3D G3DSA:3.30.1360.60 4 80 5.6E-29 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 SUPERFAMILY SSF55604 6 80 1.7E-22 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 487 607 8.3E-45 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS02400 5e65629d46c087b72eaef91fdc7222ae 633 PANTHER PTHR30175 4 582 6.0E-166 T 21-04-2016 HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 Gene3D G3DSA:3.40.50.10170 1 155 5.0E-41 T 21-04-2016 HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 280 2.9E-86 T 21-04-2016 IPR003797 DegV HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 PANTHER PTHR33434:SF3 1 281 1.4E-67 T 21-04-2016 HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 SUPERFAMILY SSF82549 1 283 1.57E-80 T 21-04-2016 HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 PANTHER PTHR33434 1 281 1.4E-67 T 21-04-2016 HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 281 5.4E-80 T 21-04-2016 IPR003797 DegV HSISS4_RS00550 85ecd900da651452c09c93e5da18866a 286 Gene3D G3DSA:3.30.1180.10 158 283 3.4E-40 T 21-04-2016 HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 PANTHER PTHR10804:SF106 1 360 3.0E-175 T 21-04-2016 HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 SUPERFAMILY SSF55920 133 357 4.58E-80 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 SUPERFAMILY SSF53092 1 131 1.33E-22 T 21-04-2016 IPR028980 Creatinase/Aminopeptidase P, N-terminal HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 Gene3D G3DSA:3.40.350.10 3 131 3.3E-24 T 21-04-2016 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 133 1.6E-17 T 21-04-2016 IPR000587 Creatinase, N-terminal GO:0016787 HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 Pfam PF00557 Metallopeptidase family M24 141 342 4.1E-60 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 PANTHER PTHR10804 1 360 3.0E-175 T 21-04-2016 HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 21-04-2016 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 Gene3D G3DSA:3.90.230.10 132 355 1.5E-81 T 21-04-2016 IPR000994 Peptidase M24, structural domain HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 PRINTS PR00599 Methionine aminopeptidase-1 signature 310 322 8.9E-5 T 21-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 203 8.9E-5 T 21-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HSISS4_RS02960 1cce6e10cfa3b3d8070c43d89fc28d34 360 PRINTS PR00599 Methionine aminopeptidase-1 signature 212 228 8.9E-5 T 21-04-2016 IPR001714 Peptidase M24, methionine aminopeptidase HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 PANTHER PTHR14969:SF21 28 162 7.0E-20 T 21-04-2016 HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 Pfam PF01569 PAP2 superfamily 58 161 1.3E-17 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 SMART SM00014 52 161 2.2E-12 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 SUPERFAMILY SSF48317 32 161 9.42E-27 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 PANTHER PTHR14969 28 162 7.0E-20 T 21-04-2016 HSISS4_RS01025 21d06ebbc5c9ffada2be509db27b8708 162 Gene3D G3DSA:1.20.144.10 33 161 2.8E-27 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS07385 72ac1e9b10588245c4485d48cdeb16d8 614 Pfam PF13520 Amino acid permease 26 450 2.3E-28 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS07385 72ac1e9b10588245c4485d48cdeb16d8 614 PANTHER PTHR11785:SF125 25 475 5.1E-160 T 21-04-2016 HSISS4_RS07385 72ac1e9b10588245c4485d48cdeb16d8 614 PANTHER PTHR11785:SF125 514 526 5.1E-160 T 21-04-2016 HSISS4_RS07385 72ac1e9b10588245c4485d48cdeb16d8 614 PANTHER PTHR11785 25 475 5.1E-160 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS07385 72ac1e9b10588245c4485d48cdeb16d8 614 PANTHER PTHR11785 514 526 5.1E-160 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 Pfam PF00162 Phosphoglycerate kinase 6 388 2.9E-145 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 175 197 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 317 342 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 111 126 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 144 166 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PRINTS PR00477 Phosphoglycerate kinase family signature 198 217 5.3E-92 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 Gene3D G3DSA:3.40.50.1260 4 186 1.5E-67 T 21-04-2016 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 SUPERFAMILY SSF53748 3 398 1.01E-142 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 398 39.616 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PANTHER PTHR11406 1 399 3.6E-200 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 PIRSF PIRSF000724 1 399 1.5E-130 T 21-04-2016 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 Gene3D G3DSA:3.40.50.1270 187 386 1.0E-75 T 21-04-2016 IPR015901 Phosphoglycerate kinase, C-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS08570 135611d546228cfc95356e2e99d1df58 399 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 21-04-2016 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|UniPathway: UPA00109 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 21-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 Pfam PF01259 SAICAR synthetase 5 228 1.4E-61 T 21-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 224 2.0E-71 T 21-04-2016 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 Gene3D G3DSA:3.30.470.20 93 218 2.9E-51 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 Gene3D G3DSA:3.30.200.20 5 92 4.6E-37 T 21-04-2016 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 PANTHER PTHR11609:SF2 3 231 3.1E-114 T 21-04-2016 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 SUPERFAMILY SSF56104 3 234 1.83E-79 T 21-04-2016 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 PANTHER PTHR11609 3 231 3.1E-114 T 21-04-2016 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 172 180 - T 21-04-2016 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS00215 b1a7842c5e3699c75abeefdcd4d617b1 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 3 233 33.447 T 21-04-2016 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 Gene3D G3DSA:3.30.1330.80 92 205 2.2E-45 T 21-04-2016 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 Pfam PF03306 Alpha-acetolactate decarboxylase 7 227 6.0E-74 T 21-04-2016 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939|UniPathway: UPA00626 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 TIGRFAM TIGR01252 acetolac_decarb: alpha-acetolactate decarboxylase 6 239 2.5E-86 T 21-04-2016 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939|UniPathway: UPA00626 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 SUPERFAMILY SSF117856 7 239 2.44E-75 T 21-04-2016 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 PANTHER PTHR35524 7 239 2.0E-77 T 21-04-2016 HSISS4_RS05305 7fdb880bb3667b440cb9ec070df9d2fe 239 PIRSF PIRSF001332 1 239 2.2E-93 T 21-04-2016 IPR005128 Alpha-acetolactate decarboxylase GO:0045151|GO:0047605 KEGG: 00650+4.1.1.5|KEGG: 00660+4.1.1.5|MetaCyc: PWY-5939|UniPathway: UPA00626 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 Gene3D G3DSA:3.40.630.10 289 373 1.1E-83 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 Gene3D G3DSA:3.40.630.10 3 169 1.1E-83 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 11 361 7.6E-104 T 21-04-2016 IPR017439 Amidohydrolase GO:0016787 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 PANTHER PTHR11014:SF107 1 377 7.7E-142 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 Pfam PF01546 Peptidase family M20/M25/M40 65 367 1.8E-25 T 21-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 PANTHER PTHR11014 1 377 7.7E-142 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 SUPERFAMILY SSF53187 3 188 1.74E-72 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 SUPERFAMILY SSF53187 289 372 1.74E-72 T 21-04-2016 HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 Gene3D G3DSA:3.30.70.360 172 288 1.9E-33 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 Pfam PF07687 Peptidase dimerisation domain 173 271 1.5E-6 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 SUPERFAMILY SSF55031 172 287 1.64E-26 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS02560 d85b01d03f57169d4c379b137771205a 381 PIRSF PIRSF005962 1 376 4.8E-108 T 21-04-2016 IPR017439 Amidohydrolase GO:0016787 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 Pfam PF01725 Ham1 family 127 315 1.7E-49 T 21-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 PANTHER PTHR11067 120 317 6.9E-67 T 21-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 Gene3D G3DSA:3.90.950.10 126 318 9.2E-73 T 21-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 125 319 46.799 T 21-04-2016 IPR020922 Non-canonical purine NTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 127 317 6.1E-53 T 21-04-2016 IPR002637 Ham1-like protein GO:0016787 KEGG: 00230+3.6.1.19|KEGG: 00240+3.6.1.19|KEGG: 00983+3.6.1.19|MetaCyc: PWY-7206 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 PANTHER PTHR11067:SF9 120 317 6.9E-67 T 21-04-2016 HSISS4_RS01225 df9f0ee1068a90bec28018044f2719f8 324 SUPERFAMILY SSF52972 127 317 8.11E-62 T 21-04-2016 IPR029001 Inosine triphosphate pyrophosphatase-like HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 SUPERFAMILY SSF51430 4 267 4.45E-84 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PRINTS PR00069 Aldo-keto reductase signature 35 59 7.8E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PRINTS PR00069 Aldo-keto reductase signature 193 217 7.8E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PRINTS PR00069 Aldo-keto reductase signature 120 137 7.8E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PRINTS PR00069 Aldo-keto reductase signature 91 109 7.8E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PRINTS PR00069 Aldo-keto reductase signature 154 183 7.8E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 PANTHER PTHR11732 1 259 6.4E-123 T 21-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 Pfam PF00248 Aldo/keto reductase family 15 257 5.0E-43 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 Gene3D G3DSA:3.20.20.100 3 264 5.2E-94 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 39 56 - T 21-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HSISS4_RS02065 4a02c1793356aa67380af41e7a2a37b0 281 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 120 137 - T 21-04-2016 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SMART SM00316 627 708 7.3E-14 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 Pfam PF00773 RNB domain 252 579 1.4E-113 T 21-04-2016 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 PANTHER PTHR23355:SF9 3 788 5.5E-228 T 21-04-2016 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 67 706 4.2E-187 T 21-04-2016 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 Hamap MF_01895 Ribonuclease R [rnr]. 18 708 54.626 T 21-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 Gene3D G3DSA:2.40.50.140 629 718 1.9E-18 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 ProSitePatterns PS01175 Ribonuclease II family signature. 548 572 - T 21-04-2016 IPR022966 Ribonuclease II/R, conserved site HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 Pfam PF00575 S1 RNA binding domain 627 706 1.3E-13 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SUPERFAMILY SSF50249 213 626 4.28E-141 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SUPERFAMILY SSF50249 67 135 1.07E-11 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 707 3.0E-248 T 21-04-2016 IPR011805 Ribonuclease R GO:0003723|GO:0004518 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 PANTHER PTHR23355 3 788 5.5E-228 T 21-04-2016 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 Pfam PF08206 Ribonuclease B OB domain 72 129 1.9E-16 T 21-04-2016 IPR013223 Ribonuclease B, N-terminal OB domain HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SUPERFAMILY SSF50249 126 227 1.83E-6 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SMART SM00955 252 581 5.9E-173 T 21-04-2016 HSISS4_RS02940 713a731e068e11ce064a373721039b58 817 SUPERFAMILY SSF50249 629 706 1.86E-17 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 30 556 2.7E-177 T 21-04-2016 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 PANTHER PTHR30255 2 729 1.2E-274 T 21-04-2016 HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 586 731 1.2E-33 T 21-04-2016 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 SUPERFAMILY SSF64182 58 435 2.88E-115 T 21-04-2016 HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 Pfam PF02272 DHHA1 domain 370 430 1.4E-10 T 21-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 PANTHER PTHR30255:SF2 2 729 1.2E-274 T 21-04-2016 HSISS4_RS04025 b2f1b7fe0227b0f65207b8a2a5ebed91 733 Pfam PF01368 DHH family 84 228 2.0E-14 T 21-04-2016 IPR001667 DDH domain HSISS4_RS05790 83b54656c9a543c9d5a5d1dec93f00b7 201 PANTHER PTHR17490 6 201 2.6E-59 T 21-04-2016 HSISS4_RS05790 83b54656c9a543c9d5a5d1dec93f00b7 201 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 189 3.0E-48 T 21-04-2016 IPR006070 YrdC-like domain GO:0003725 HSISS4_RS05790 83b54656c9a543c9d5a5d1dec93f00b7 201 Pfam PF01300 Telomere recombination 11 184 4.1E-44 T 21-04-2016 IPR006070 YrdC-like domain GO:0003725 HSISS4_RS05790 83b54656c9a543c9d5a5d1dec93f00b7 201 Gene3D G3DSA:3.90.870.10 6 197 7.5E-59 T 21-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HSISS4_RS05790 83b54656c9a543c9d5a5d1dec93f00b7 201 SUPERFAMILY SSF55821 6 197 3.97E-53 T 21-04-2016 IPR017945 DHBP synthase RibB-like alpha/beta domain HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 Gene3D G3DSA:3.40.50.2020 1 190 5.4E-67 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 Hamap MF_01184 Xanthine phosphoribosyltransferase [xpt]. 1 189 41.273 T 21-04-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 PANTHER PTHR11776 1 188 1.8E-81 T 21-04-2016 HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 Pfam PF00156 Phosphoribosyl transferase domain 35 152 1.6E-8 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 TIGRFAM TIGR01744 XPRTase: xanthine phosphoribosyltransferase 1 189 3.0E-78 T 21-04-2016 IPR010079 Xanthine phosphoribosyltransferase GO:0016763|GO:0043101|GO:0046110 KEGG: 00230+2.4.2.22|UniPathway: UPA00602 HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 PANTHER PTHR11776:SF1 1 188 1.8E-81 T 21-04-2016 HSISS4_RS06155 8a1e524b75757c5d72b7d739db55b95e 193 SUPERFAMILY SSF53271 1 188 2.13E-48 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 17 32 3.5E-44 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 3.5E-44 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 57 77 3.5E-44 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 109 128 3.5E-44 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PRINTS PR00127 Clp protease catalytic subunit P signature 88 105 3.5E-44 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 Gene3D G3DSA:3.90.226.10 2 193 3.4E-78 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 88 99 - T 21-04-2016 IPR018215 ClpP, Ser active site HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PANTHER PTHR10381 1 194 3.0E-110 T 21-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 Pfam PF00574 Clp protease 10 192 7.0E-79 T 21-04-2016 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 SUPERFAMILY SSF52096 8 192 1.64E-67 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 1 193 39.858 T 21-04-2016 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 PANTHER PTHR10381:SF22 1 194 3.0E-110 T 21-04-2016 HSISS4_RS01620 79bdcfbd81ab858eb5d281306eb7cb0e 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 110 123 - T 21-04-2016 IPR033135 ClpP, histidine active site HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Gene3D G3DSA:3.40.50.300 3 100 5.6E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Gene3D G3DSA:3.40.50.300 320 533 3.7E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Gene3D G3DSA:3.40.50.300 132 281 5.6E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 SUPERFAMILY SSF52540 293 514 1.03E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Pfam PF12848 ABC transporter 224 305 8.4E-21 T 21-04-2016 IPR032781 ABC-transporter extension domain HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 SUPERFAMILY SSF52540 125 252 4.36E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 SUPERFAMILY SSF52540 2 92 4.36E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 SMART SM00382 26 228 7.7E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 SMART SM00382 344 512 0.4 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 PANTHER PTHR19211 1 534 0.0 T 21-04-2016 HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 PANTHER PTHR19211:SF38 1 534 0.0 T 21-04-2016 HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Pfam PF00005 ABC transporter 18 184 1.9E-23 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS09710 1b1b37db95f45bf429b6ed818d7c1ed9 540 Pfam PF00005 ABC transporter 335 467 4.3E-13 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 Pfam PF01938 TRAM domain 4 59 6.2E-6 T 21-04-2016 IPR002792 TRAM domain HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 Gene3D G3DSA:2.40.50.140 1 79 1.4E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 PANTHER PTHR11061 3 451 1.1E-258 T 21-04-2016 HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 SUPERFAMILY SSF53335 68 449 9.64E-77 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 21-04-2016 IPR030390 RNA methyltransferase TrmA, active site HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 89 450 7.8E-23 T 21-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 PANTHER PTHR11061:SF35 3 451 1.1E-258 T 21-04-2016 HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 17 442 6.1E-132 T 21-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 Gene3D G3DSA:3.40.50.150 247 448 9.4E-63 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 432 442 - T 21-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site HSISS4_RS01760 fce426ed18e06c6a716c7de27f78ffea 451 SUPERFAMILY SSF50249 3 59 1.2E-12 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 Gene3D G3DSA:2.40.150.20 1 122 1.5E-51 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 25.914 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 21-04-2016 IPR019972 Ribosomal protein L14P, conserved site HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 SUPERFAMILY SSF50193 1 122 2.09E-49 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 PANTHER PTHR11761 1 122 6.5E-73 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 1.5E-52 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 SMART SM01374 1 122 4.6E-84 T 21-04-2016 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09300 2da61288b575c6028a8b8554dcd1babf 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 3.6E-56 T 21-04-2016 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS01900 064d99e7c4f6e5bcbcf4af240bed8ccf 439 TIGRFAM TIGR02919 TIGR02919: accessory Sec system glycosyltransferase GtfB 1 438 3.5E-174 T 21-04-2016 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 HSISS4_RS01900 064d99e7c4f6e5bcbcf4af240bed8ccf 439 Hamap MF_01473 Glycosyltransferase stabilizing protein Gtf2 [gtf2]. 1 439 37.334 T 21-04-2016 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 Gene3D G3DSA:3.40.190.10 211 339 1.4E-16 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 520 2.0E-47 T 21-04-2016 IPR000914 Solute-binding protein family 5 domain HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 Gene3D G3DSA:3.10.105.10 340 583 1.5E-27 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 SUPERFAMILY SSF53850 29 588 1.32E-75 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 Gene3D G3DSA:3.90.76.10 41 210 1.4E-40 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290:SF10 330 388 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290:SF10 1 136 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290:SF10 157 311 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290:SF10 404 630 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 80 102 - T 21-04-2016 IPR023765 Solute-binding protein family 5, conserved site HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290 330 388 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290 1 136 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290 157 311 1.8E-127 T 21-04-2016 HSISS4_RS07000 e1486a779ea37bce1e4cbd386fc4ae23 656 PANTHER PTHR30290 404 630 1.8E-127 T 21-04-2016 HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 PANTHER PTHR24220:SF428 3 271 7.3E-94 T 21-04-2016 HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 SMART SM00382 26 204 3.8E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 Gene3D G3DSA:3.40.50.300 1 221 5.2E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 SUPERFAMILY SSF52540 2 220 3.16E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 Pfam PF00005 ABC transporter 17 157 1.1E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05095 78ccb36fbc175ea9a238714e7c85e747 275 PANTHER PTHR24220 3 271 7.3E-94 T 21-04-2016 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 SUPERFAMILY SSF50156 206 288 1.84E-11 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 Pfam PF02163 Peptidase family M50 6 406 3.3E-79 T 21-04-2016 IPR008915 Peptidase M50 GO:0004222|GO:0006508 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 PANTHER PTHR22939 206 420 6.3E-67 T 21-04-2016 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 3 418 1.4E-69 T 21-04-2016 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 PANTHER PTHR22939:SF78 206 420 6.3E-67 T 21-04-2016 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 Gene3D G3DSA:2.30.42.10 166 274 1.5E-18 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS00965 541dee0a01747dbdb1806b94c22035bc 420 Pfam PF13180 PDZ domain 205 272 6.1E-8 T 21-04-2016 IPR001478 PDZ domain GO:0005515 HSISS4_RS09645 6f296abe2c205a5c7c4ec0042ce769ac 264 PANTHER PTHR33514:SF2 1 264 5.5E-124 T 21-04-2016 HSISS4_RS09645 6f296abe2c205a5c7c4ec0042ce769ac 264 PANTHER PTHR33514 1 264 5.5E-124 T 21-04-2016 HSISS4_RS09645 6f296abe2c205a5c7c4ec0042ce769ac 264 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 1 264 36.378 T 21-04-2016 IPR024919 ECF transporter transmembrane protein EcfT GO:0005215|GO:0006810|GO:0016021 HSISS4_RS09645 6f296abe2c205a5c7c4ec0042ce769ac 264 Pfam PF02361 Cobalt transport protein 14 234 9.5E-51 T 21-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 SUPERFAMILY SSF46894 125 213 5.95E-15 T 21-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 Gene3D G3DSA:1.10.10.10 128 210 9.6E-17 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 Pfam PF00072 Response regulator receiver domain 5 114 5.1E-29 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 SMART SM00448 3 114 2.8E-43 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 207 2.1E-14 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 PANTHER PTHR26402 3 212 3.3E-62 T 21-04-2016 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 PANTHER PTHR26402:SF316 3 212 3.3E-62 T 21-04-2016 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 SUPERFAMILY SSF52172 3 122 4.13E-39 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 SMART SM00862 147 222 1.1E-10 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS02005 2a7e40c3780ed8514e80eba12c626919 225 Gene3D G3DSA:3.40.50.2300 3 122 2.5E-40 T 21-04-2016 HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 SUPERFAMILY SSF52540 7 228 5.06E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 SMART SM00382 35 222 2.6E-18 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 PANTHER PTHR24220 8 228 3.6E-122 T 21-04-2016 HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 PANTHER PTHR24220:SF578 8 228 3.6E-122 T 21-04-2016 HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 Gene3D G3DSA:3.40.50.300 6 228 2.6E-72 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02485 884e1df196f1c4966f0adf177252cfd2 234 Pfam PF00005 ABC transporter 26 174 9.6E-35 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 1 622 37.566 T 21-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 PANTHER PTHR10357 12 621 2.0E-276 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 PANTHER PTHR10357:SF160 12 621 2.0E-276 T 21-04-2016 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Pfam PF00128 Alpha amylase, catalytic domain 170 248 2.1E-7 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 22 101 5.5E-16 T 21-04-2016 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 SMART SM00642 145 503 9.6E-8 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 SUPERFAMILY SSF81296 13 110 4.2E-17 T 21-04-2016 IPR014756 Immunoglobulin E-set HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 SUPERFAMILY SSF51445 77 509 1.34E-101 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 7 618 7.9E-200 T 21-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 PIRSF PIRSF000463 1 626 2.8E-241 T 21-04-2016 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Gene3D G3DSA:2.60.40.1180 516 621 1.7E-27 T 21-04-2016 IPR013780 Glycosyl hydrolase, all-beta HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Gene3D G3DSA:3.20.20.80 139 504 6.2E-84 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Gene3D G3DSA:2.60.40.10 10 114 5.5E-26 T 21-04-2016 IPR013783 Immunoglobulin-like fold HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 SUPERFAMILY SSF51011 517 622 1.3E-24 T 21-04-2016 HSISS4_RS06855 cf100d0f557b438b1011777d4718573b 626 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 522 621 6.2E-17 T 21-04-2016 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: REACT_474 HSISS4_RS06495 071351a3ba5e5180d5462b910dfb854b 248 PIRSF PIRSF033101 1 243 5.8E-44 T 21-04-2016 IPR011397 Uncharacterised conserved protein UCP033101 HSISS4_RS06495 071351a3ba5e5180d5462b910dfb854b 248 Pfam PF10086 Putative membrane peptidase family (DUF2324) 12 221 6.6E-43 T 21-04-2016 IPR011397 Uncharacterised conserved protein UCP033101 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 ProSitePatterns PS01319 Ribosome-binding factor A signature. 76 97 - T 21-04-2016 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 97 1.0E-44 T 21-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 Gene3D G3DSA:3.30.300.20 3 116 1.5E-36 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 117 21.405 T 21-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 Pfam PF02033 Ribosome-binding factor A 6 110 2.3E-29 T 21-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 PANTHER PTHR33515 1 117 2.1E-39 T 21-04-2016 HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 SUPERFAMILY SSF89919 1 113 1.83E-29 T 21-04-2016 IPR023799 Ribosome-binding factor A domain HSISS4_RS01565 32ea30c070caa29ea4a9e94b2772744b 117 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 115 5.5E-29 T 21-04-2016 IPR000238 Ribosome-binding factor A GO:0006364 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 16 231 4.5E-44 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PANTHER PTHR11410 1 235 2.5E-52 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 Pfam PF00119 ATP synthase A chain 22 228 4.4E-50 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PANTHER PTHR11410:SF7 1 235 2.5E-52 T 21-04-2016 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PRINTS PR00123 ATP synthase A subunit signature 162 184 4.9E-17 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PRINTS PR00123 ATP synthase A subunit signature 215 230 4.9E-17 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PRINTS PR00123 ATP synthase A subunit signature 146 161 4.9E-17 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 PRINTS PR00123 ATP synthase A subunit signature 78 94 4.9E-17 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 SUPERFAMILY SSF81336 70 229 3.92E-38 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 Hamap MF_01393 ATP synthase subunit a [atpB]. 14 235 13.822 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 21-04-2016 IPR023011 ATPase, F0 complex, subunit A, active site HSISS4_RS02245 c11c7509f6456f00faac805dd4da86c6 235 Gene3D G3DSA:1.20.120.220 71 234 1.0E-41 T 21-04-2016 IPR000568 ATPase, F0 complex, subunit A GO:0015078|GO:0015986 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PANTHER PTHR24093 16 790 0.0 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PANTHER PTHR24093 806 926 0.0 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Pfam PF00122 E1-E2 ATPase 89 323 2.1E-69 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 70 84 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 251 273 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 325 346 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 795 815 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 726 747 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 470 488 3.8E-25 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PANTHER PTHR24093:SF268 16 790 0.0 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PANTHER PTHR24093:SF268 806 926 0.0 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF81660 339 553 9.16E-55 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF81653 120 230 4.18E-30 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF81665 232 326 1.15E-114 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF81665 13 121 1.15E-114 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF81665 702 920 1.15E-114 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF56784 330 350 1.39E-61 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SUPERFAMILY SSF56784 501 758 1.39E-61 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 334 340 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Pfam PF13246 Cation transport ATPase (P-type) 396 485 1.9E-17 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Gene3D G3DSA:1.20.1110.10 63 115 2.3E-94 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Gene3D G3DSA:1.20.1110.10 621 920 2.3E-94 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Pfam PF00689 Cation transporting ATPase, C-terminus 738 919 1.1E-47 T 21-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Gene3D G3DSA:2.70.150.10 116 230 9.1E-44 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Gene3D G3DSA:2.70.150.10 27 62 9.1E-44 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Gene3D G3DSA:3.40.1110.10 322 556 7.3E-63 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 626 732 1.0E-32 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 90 353 9.7E-40 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 SMART SM00831 10 83 3.6E-23 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 77 2.7E-20 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 Pfam PF08282 haloacid dehalogenase-like hydrolase 643 698 7.9E-5 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 168 182 6.8E-41 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 560 6.8E-41 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 581 6.8E-41 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 671 6.8E-41 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 676 688 6.8E-41 T 21-04-2016 HSISS4_RS01590 fa1834c5506ee2dadc79031a713f7d8c 926 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 332 346 6.8E-41 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF56784 339 359 1.32E-40 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF56784 470 713 1.32E-40 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Gene3D G3DSA:1.20.1110.10 64 124 5.2E-65 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Gene3D G3DSA:1.20.1110.10 583 877 5.2E-65 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 343 349 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 5 885 0.0 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SMART SM00831 10 83 3.6E-6 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Pfam PF00702 haloacid dehalogenase-like hydrolase 337 626 1.4E-18 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 839 860 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 742 758 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 271 290 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 254 270 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 672 687 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 375 388 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 722 735 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 690 701 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PRINTS PR01836 Magnesium-transporting ATPase signature 789 810 7.6E-65 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Pfam PF00689 Cation transporting ATPase, C-terminus 697 876 6.1E-12 T 21-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Gene3D G3DSA:3.40.1110.10 333 521 2.9E-33 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PANTHER PTHR24093 2 885 0.0 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 PANTHER PTHR24093:SF128 2 885 0.0 T 21-04-2016 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF81653 131 240 2.22E-27 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 585 703 4.8E-27 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 99 200 3.7E-18 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 234 356 1.7E-18 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 78 1.2E-12 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Gene3D G3DSA:2.70.150.10 125 242 5.1E-39 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Gene3D G3DSA:2.70.150.10 28 63 5.1E-39 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 Pfam PF00122 E1-E2 ATPase 97 332 1.2E-54 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF81665 242 335 2.22E-97 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF81665 13 130 2.22E-97 T 21-04-2016 HSISS4_RS02630 5dbad37fac5c3bb8ad0145c10e66b185 886 SUPERFAMILY SSF81665 663 883 2.22E-97 T 21-04-2016 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 Pfam PF01016 Ribosomal L27 protein 12 91 1.2E-33 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 11 91 2.2E-37 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 11 94 26.503 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 38 79 1.0E-17 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 Gene3D G3DSA:2.40.50.100 30 94 2.5E-30 T 21-04-2016 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 SUPERFAMILY SSF110324 12 93 2.48E-31 T 21-04-2016 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 PRINTS PR00063 Ribosomal protein L27 signature 39 63 3.1E-36 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 PRINTS PR00063 Ribosomal protein L27 signature 64 88 3.1E-36 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 PRINTS PR00063 Ribosomal protein L27 signature 14 38 3.1E-36 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 PANTHER PTHR15893 8 95 1.9E-44 T 21-04-2016 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01915 8a1ee341ae98f6bea8b3e7a0e6c8490a 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 44 58 - T 21-04-2016 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 Gene3D G3DSA:3.30.930.10 19 311 7.0E-59 T 21-04-2016 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 Pfam PF13393 Histidyl-tRNA synthetase 9 310 2.1E-60 T 21-04-2016 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 PIRSF PIRSF001549 1 321 1.2E-51 T 21-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 PANTHER PTHR11476 9 316 6.7E-60 T 21-04-2016 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 Reactome: REACT_71 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 326 27.217 T 21-04-2016 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 UniPathway: UPA00031 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 SUPERFAMILY SSF55681 7 315 5.18E-55 T 21-04-2016 HSISS4_RS03885 0208e1c98fb73c57ceff63faa65c8cba 326 PANTHER PTHR11476:SF5 9 316 6.7E-60 T 21-04-2016 HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 SUPERFAMILY SSF57716 4 61 3.21E-21 T 21-04-2016 HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.507 T 21-04-2016 IPR023053 Ribosomal protein S14, type Z HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 Gene3D G3DSA:4.10.830.10 2 61 2.2E-27 T 21-04-2016 HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 PANTHER PTHR19836 15 61 1.1E-34 T 21-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 21-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09285 2fde9fa644afc4f966b5f6eeebd7588a 61 Pfam PF00253 Ribosomal protein S14p/S29e 12 60 3.8E-24 T 21-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 183 3.8E-31 T 21-04-2016 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 238 320 1.0E-29 T 21-04-2016 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 320 64.62 T 21-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 PANTHER PTHR18919 27 319 4.6E-109 T 21-04-2016 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 319 6.1E-101 T 21-04-2016 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381|UniPathway: UPA00094 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 PANTHER PTHR18919:SF109 27 319 4.6E-109 T 21-04-2016 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 Gene3D G3DSA:3.40.47.10 4 160 3.3E-62 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 SUPERFAMILY SSF53901 3 319 1.92E-57 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01790 8e268a9c88914ee55fa548e117d02d1f 320 Gene3D G3DSA:3.40.47.10 161 319 1.0E-42 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01925 6ae260e994b635f97cc7aac2843ab5c7 124 Gene3D G3DSA:3.10.420.10 1 124 7.2E-54 T 21-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 HSISS4_RS01925 6ae260e994b635f97cc7aac2843ab5c7 124 PIRSF PIRSF031568 1 124 7.8E-58 T 21-04-2016 IPR009530 Protein of unknown function DUF1149 HSISS4_RS01925 6ae260e994b635f97cc7aac2843ab5c7 124 SUPERFAMILY SSF54611 1 124 1.57E-50 T 21-04-2016 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 HSISS4_RS01925 6ae260e994b635f97cc7aac2843ab5c7 124 Pfam PF06619 Protein of unknown function (DUF1149) 1 124 2.2E-48 T 21-04-2016 IPR009530 Protein of unknown function DUF1149 HSISS4_RS07730 7b4ee5a45d571df06ea033edaac7a238 178 Gene3D G3DSA:1.10.10.10 6 31 1.0E-5 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07730 7b4ee5a45d571df06ea033edaac7a238 178 Pfam PF08279 HTH domain 6 33 5.6E-5 T 21-04-2016 IPR013196 Helix-turn-helix, type 11 HSISS4_RS07730 7b4ee5a45d571df06ea033edaac7a238 178 Pfam PF04394 Protein of unknown function, DUF536 104 146 1.8E-18 T 21-04-2016 IPR007489 Domain of unknown function DUF536 HSISS4_RS01295 652a32af71aec90ae3ee540a9dea01a1 110 Pfam PF05656 Protein of unknown function (DUF805) 12 105 1.6E-15 T 21-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Gene3D G3DSA:3.40.1190.10 107 331 1.4E-51 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 SUPERFAMILY SSF53623 79 340 9.94E-45 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Pfam PF08245 Mur ligase middle domain 117 308 8.7E-31 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 SUPERFAMILY SSF53244 328 472 3.27E-30 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 PANTHER PTHR23135 22 481 6.8E-120 T 21-04-2016 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 2 481 27.919 T 21-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Gene3D G3DSA:3.90.190.20 332 470 8.8E-35 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 35 480 5.8E-89 T 21-04-2016 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 328 412 5.4E-16 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 SUPERFAMILY SSF63418 15 107 9.55E-18 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 Gene3D G3DSA:3.40.1390.10 32 105 3.3E-9 T 21-04-2016 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01580 fc63741fdc84002900f58517e782d5fe 481 PANTHER PTHR23135:SF4 22 481 6.8E-120 T 21-04-2016 HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 PANTHER PTHR21569 1 130 1.5E-69 T 21-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 4.8E-49 T 21-04-2016 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 Gene3D G3DSA:3.30.230.10 5 130 3.3E-51 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 SUPERFAMILY SSF54211 5 130 1.74E-48 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 33.535 T 21-04-2016 IPR023035 Ribosomal protein S9, bacterial/plastid HSISS4_RS00570 39b2f7e2c42cb3c4911cd9dc7d10208c 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 21-04-2016 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 Pfam PF00005 ABC transporter 21 169 5.3E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 SMART SM00382 30 217 6.7E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 SUPERFAMILY SSF52540 5 239 2.03E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 PIRSF PIRSF039085 2 244 9.7E-102 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 PANTHER PTHR24220 7 241 2.8E-120 T 21-04-2016 HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 Gene3D G3DSA:3.40.50.300 4 240 1.9E-84 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07605 ea989ddbf3c8397579a7bd8f09f28b6f 252 PANTHER PTHR24220:SF327 7 241 2.8E-120 T 21-04-2016 HSISS4_RS03525 040ef6bdd07fdedbee152a83dd306ee2 334 SMART SM00892 53 248 7.7E-15 T 21-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 HSISS4_RS03525 040ef6bdd07fdedbee152a83dd306ee2 334 Pfam PF13930 DNA/RNA non-specific endonuclease 63 199 2.4E-23 T 21-04-2016 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 5 82 8.0E-37 T 21-04-2016 IPR007920 Protein of unknown function UPF0223 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 Pfam PF05256 Uncharacterised protein family (UPF0223) 5 89 1.7E-35 T 21-04-2016 IPR007920 Protein of unknown function UPF0223 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 SUPERFAMILY SSF158504 7 90 5.75E-33 T 21-04-2016 IPR023324 BH2638-like domain HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 PIRSF PIRSF037260 2 93 2.4E-39 T 21-04-2016 IPR007920 Protein of unknown function UPF0223 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 PANTHER PTHR41305 5 93 6.3E-31 T 21-04-2016 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 Hamap MF_01041 UPF0223 protein . 4 91 24.37 T 21-04-2016 IPR007920 Protein of unknown function UPF0223 HSISS4_RS04910 ac4ff4b0d26adf3874e5ab99152209bf 93 Gene3D G3DSA:1.10.220.80 15 92 7.2E-34 T 21-04-2016 IPR023324 BH2638-like domain HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 PANTHER PTHR11142 1 248 2.7E-90 T 21-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 Pfam PF01416 tRNA pseudouridine synthase 6 105 1.4E-10 T 21-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 Pfam PF01416 tRNA pseudouridine synthase 144 248 1.9E-29 T 21-04-2016 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 PIRSF PIRSF001430 1 248 1.4E-75 T 21-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 5 242 2.6E-64 T 21-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 247 35.464 T 21-04-2016 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 Gene3D G3DSA:3.30.70.660 108 248 3.3E-45 T 21-04-2016 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 Gene3D G3DSA:3.30.70.580 1 105 9.4E-36 T 21-04-2016 IPR020094 Pseudouridine synthase I, TruA, N-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 SUPERFAMILY SSF55120 1 247 4.03E-82 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00685 7d8aa7d7c2b5825fa2901e8333989062 248 PANTHER PTHR11142:SF0 1 248 2.7E-90 T 21-04-2016 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 235 42.551 T 21-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 PANTHER PTHR21234 1 236 5.2E-67 T 21-04-2016 IPR018017 Nucleoside phosphorylase HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 232 1.2E-87 T 21-04-2016 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 21-04-2016 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 Gene3D G3DSA:3.40.50.1580 8 234 2.6E-81 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 SUPERFAMILY SSF53167 2 234 1.13E-84 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 Pfam PF01048 Phosphorylase superfamily 16 220 4.0E-42 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04580 41bed055da10be6b992a93c2ec8d40b1 236 PANTHER PTHR21234:SF8 1 236 5.2E-67 T 21-04-2016 HSISS4_RS05290 482b178a02147485c724e60531714783 254 SMART SM00506 79 219 1.0E-22 T 21-04-2016 IPR002589 Macro domain HSISS4_RS05290 482b178a02147485c724e60531714783 254 PANTHER PTHR11106 80 252 1.2E-67 T 21-04-2016 HSISS4_RS05290 482b178a02147485c724e60531714783 254 SUPERFAMILY SSF52949 77 253 4.37E-53 T 21-04-2016 HSISS4_RS05290 482b178a02147485c724e60531714783 254 Pfam PF01661 Macro domain 96 219 2.8E-34 T 21-04-2016 IPR002589 Macro domain HSISS4_RS05290 482b178a02147485c724e60531714783 254 Gene3D G3DSA:3.40.220.10 78 253 9.7E-61 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 6 39 1.7E-10 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 Pfam PF08363 Glucan-binding protein C 872 970 6.9E-12 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 Pfam PF08363 Glucan-binding protein C 560 812 3.0E-22 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1228 1262 1.3E-5 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 PRINTS PR01217 Proline rich extensin signature 1085 1102 9.7E-9 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 PRINTS PR01217 Proline rich extensin signature 1012 1024 9.7E-9 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 PRINTS PR01217 Proline rich extensin signature 1038 1059 9.7E-9 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 PRINTS PR01217 Proline rich extensin signature 1059 1075 9.7E-9 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 PRINTS PR01217 Proline rich extensin signature 981 997 9.7E-9 T 21-04-2016 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 Pfam PF04650 YSIRK type signal peptide 7 28 5.8E-10 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 SUPERFAMILY SSF74914 870 986 4.32E-15 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS04540 9088eab2c32a12d9c8a58b8cef2f9390 1262 SUPERFAMILY SSF74914 516 766 6.28E-29 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 PANTHER PTHR10000 5 215 6.1E-80 T 21-04-2016 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 7 177 2.8E-33 T 21-04-2016 IPR006383 HAD-superfamily hydrolase, subfamily IB, PSPase-like GO:0008152|GO:0016791 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 Gene3D G3DSA:1.10.150.210 17 67 1.3E-27 T 21-04-2016 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|UniPathway: UPA00135 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 Gene3D G3DSA:3.40.50.1000 68 197 4.2E-46 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 PANTHER PTHR10000:SF7 5 215 6.1E-80 T 21-04-2016 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 91 101 5.2E-5 T 21-04-2016 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 165 184 5.2E-5 T 21-04-2016 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 4 210 2.9E-76 T 21-04-2016 HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 SUPERFAMILY SSF56784 6 212 5.85E-51 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07260 4326b9cdf23cc44f337d31102e09ee93 215 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 175 8.9E-27 T 21-04-2016 HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 4288 4320 9.9E-6 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 3538 3595 1.8E-6 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 2558 2612 1.2E-6 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 4191 4240 9.1E-5 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1891 1960 1.0E-5 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 3204 3267 4.4E-6 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1439 1521 1.1E-12 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 989 1071 7.1E-13 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 755 845 1.4E-13 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1103 1184 1.6E-10 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1553 1629 9.5E-5 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 3865 3933 5.7E-7 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1329 1408 3.6E-11 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 2231 2285 1.4E-6 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 1215 1297 9.9E-12 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 2888 2937 0.013 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF12892 T surface-antigen of pili 877 958 2.7E-9 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 3315 3462 1.2E-19 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1994 2145 1.2E-21 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 2985 3118 3.7E-15 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 3642 3791 6.8E-24 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 2661 2814 7.2E-27 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 2334 2484 1.4E-21 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 3968 4107 1.1E-16 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR04228 isopep_sspB_C2: adhesin isopeptide-forming adherence domain 1673 1808 8.8E-12 T 21-04-2016 IPR026345 Adhesin isopeptide-forming adherence domain HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF04650 YSIRK type signal peptide 6 30 2.1E-10 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 39 2.9E-12 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 Pfam PF00746 Gram positive anchor 4280 4318 5.2E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 4177 4239 2.0E-9 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1316 1379 1.3E-12 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1428 1490 2.2E-13 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1877 1942 1.4E-8 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 2545 2609 3.5E-11 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 744 814 4.8E-20 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 3852 3917 3.0E-11 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1540 1604 2.1E-8 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1090 1155 2.0E-10 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 3190 3263 3.2E-11 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 978 1040 1.4E-15 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 2205 2282 1.0E-9 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 3525 3590 1.7E-12 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 864 929 2.4E-10 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS06790 f914c2284b0a86723ce6347cbc2e9fe9 4321 TIGRFAM TIGR03786 strep_pil_rpt: streptococcal pilin isopeptide linkage domain 1204 1266 1.8E-14 T 21-04-2016 IPR022464 Streptococcal pilin isopeptide linker HSISS4_RS09660 89b2beb00833905a3dfc47ec039e7554 180 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 21-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HSISS4_RS09660 89b2beb00833905a3dfc47ec039e7554 180 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 74 5.3E-17 T 21-04-2016 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 HSISS4_RS09660 89b2beb00833905a3dfc47ec039e7554 180 PANTHER PTHR14269 6 168 3.6E-45 T 21-04-2016 HSISS4_RS09660 89b2beb00833905a3dfc47ec039e7554 180 PIRSF PIRSF000847 3 180 2.4E-49 T 21-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 HSISS4_RS09660 89b2beb00833905a3dfc47ec039e7554 180 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 6 169 4.9E-53 T 21-04-2016 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|UniPathway: UPA00084 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 SUPERFAMILY SSF63380 3 98 9.5E-21 T 21-04-2016 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PANTHER PTHR19370:SF68 6 245 4.1E-57 T 21-04-2016 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PRINTS PR00409 Phthalate dioxygenase reductase family signature 38 50 4.5E-6 T 21-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PRINTS PR00409 Phthalate dioxygenase reductase family signature 110 129 4.5E-6 T 21-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PRINTS PR00409 Phthalate dioxygenase reductase family signature 187 195 4.5E-6 T 21-04-2016 IPR000951 Phthalate dioxygenase reductase GO:0016491 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 Gene3D G3DSA:2.40.30.10 5 96 4.5E-30 T 21-04-2016 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PANTHER PTHR19370 6 245 4.1E-57 T 21-04-2016 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 Gene3D G3DSA:3.40.50.80 103 207 1.9E-33 T 21-04-2016 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 Gene3D G3DSA:2.10.240.10 215 256 2.4E-17 T 21-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 PIRSF PIRSF006816 1 257 2.2E-66 T 21-04-2016 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 UniPathway: UPA00070 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 255 1.5E-17 T 21-04-2016 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain UniPathway: UPA00070 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 SUPERFAMILY SSF52343 93 255 1.96E-30 T 21-04-2016 HSISS4_RS05070 c16ec88e4fe00d6787566f0058c8b7a5 257 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 4 257 34.601 T 21-04-2016 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit UniPathway: UPA00070 HSISS4_RS02225 f34c5ca9d2699506bcde5ea57adb7fea 192 SUPERFAMILY SSF52540 1 183 2.62E-14 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02225 f34c5ca9d2699506bcde5ea57adb7fea 192 Pfam PF13238 AAA domain 3 141 5.5E-10 T 21-04-2016 HSISS4_RS02225 f34c5ca9d2699506bcde5ea57adb7fea 192 Gene3D G3DSA:3.40.50.300 2 183 2.0E-15 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 Pfam PF02130 Uncharacterized protein family UPF0054 14 159 1.4E-39 T 21-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 37 161 1.1E-38 T 21-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 5 164 21.694 T 21-04-2016 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 Gene3D G3DSA:3.40.390.30 6 164 1.9E-43 T 21-04-2016 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 130 140 - T 21-04-2016 IPR020549 Endoribonuclease YbeY, conserved site HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 PANTHER PTHR22881 37 164 8.2E-34 T 21-04-2016 HSISS4_RS02905 a20a219af74abc309c7debd501bc2830 165 SUPERFAMILY SSF55486 2 164 2.69E-39 T 21-04-2016 HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 Gene3D G3DSA:3.30.230.30 3 129 1.6E-47 T 21-04-2016 IPR001498 Impact, N-terminal HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 SUPERFAMILY SSF54211 3 129 6.07E-43 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 Gene3D G3DSA:3.30.70.240 134 205 4.5E-7 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 PANTHER PTHR16301:SF0 2 197 2.6E-56 T 21-04-2016 HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 Pfam PF01205 Uncharacterized protein family UPF0029 17 121 1.4E-29 T 21-04-2016 IPR001498 Impact, N-terminal HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 77 106 - T 21-04-2016 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 PANTHER PTHR16301 2 197 2.6E-56 T 21-04-2016 IPR023582 Impact family HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 3 194 2.2E-61 T 21-04-2016 IPR015796 Impact family, bacterial/archaeal HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 Pfam PF09186 Domain of unknown function (DUF1949) 138 193 1.1E-10 T 21-04-2016 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal HSISS4_RS01670 f49c901f6e1e793a9ebfeca60614580a 208 SUPERFAMILY SSF54980 136 198 6.47E-7 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 232 353 6.1E-7 T 21-04-2016 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 350 4.2E-137 T 21-04-2016 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 PANTHER PTHR11669 1 502 5.8E-176 T 21-04-2016 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 SUPERFAMILY SSF52540 33 221 1.51E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 Pfam PF13177 DNA polymerase III, delta subunit 20 177 9.7E-44 T 21-04-2016 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 SMART SM00382 36 176 9.8E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 PANTHER PTHR11669:SF0 1 502 5.8E-176 T 21-04-2016 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 123 141 1.63E-5 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 40 58 1.63E-5 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 Gene3D G3DSA:1.10.8.60 166 242 2.7E-30 T 21-04-2016 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 Gene3D G3DSA:3.40.50.300 15 165 2.5E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 Gene3D G3DSA:1.20.272.10 251 350 2.5E-4 T 21-04-2016 HSISS4_RS04250 c15109f68567e80338cdef3b34890248 550 SUPERFAMILY SSF48019 249 356 3.57E-11 T 21-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 SUPERFAMILY SSF52141 3 215 4.36E-86 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 Gene3D G3DSA:3.40.470.10 3 215 8.8E-92 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 4 209 3.9E-76 T 21-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 SMART SM00986 47 205 1.7E-35 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 PANTHER PTHR11264 3 215 4.0E-116 T 21-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 SMART SM00987 47 205 1.7E-35 T 21-04-2016 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 55 64 - T 21-04-2016 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 3 216 39.489 T 21-04-2016 IPR002043 Uracil-DNA glycosylase GO:0004844|GO:0006281|GO:0006284 HSISS4_RS04725 f5455aaac087123283a6d022c41aa411 217 Pfam PF03167 Uracil DNA glycosylase superfamily 51 204 6.1E-22 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 252 2.8E-49 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 SMART SM00062 47 266 3.3E-67 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 PANTHER PTHR18966:SF191 32 261 7.8E-57 T 21-04-2016 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 Gene3D G3DSA:3.40.190.10 125 217 9.1E-24 T 21-04-2016 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 Gene3D G3DSA:3.40.190.10 44 124 8.1E-33 T 21-04-2016 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 Gene3D G3DSA:3.40.190.10 225 261 8.1E-33 T 21-04-2016 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 PANTHER PTHR18966 32 261 7.8E-57 T 21-04-2016 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 SMART SM00079 47 265 0.0038 T 21-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 70 83 - T 21-04-2016 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 HSISS4_RS07600 4b82e98029f34c36445409aea9b5cf4d 284 SUPERFAMILY SSF53850 5 261 3.01E-64 T 21-04-2016 HSISS4_RS02025 ffa106eeab063b5ac636042453fbd31a 285 SUPERFAMILY SSF50249 147 218 6.68E-5 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02025 ffa106eeab063b5ac636042453fbd31a 285 PANTHER PTHR37296 2 285 4.5E-107 T 21-04-2016 HSISS4_RS02025 ffa106eeab063b5ac636042453fbd31a 285 Pfam PF13509 S1 domain 5 62 2.2E-13 T 21-04-2016 HSISS4_RS02025 ffa106eeab063b5ac636042453fbd31a 285 PIRSF PIRSF012524 1 284 2.4E-112 T 21-04-2016 IPR014464 Conserved virulence factor B HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 SUPERFAMILY SSF55973 5 110 3.14E-42 T 21-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 245 384 4.0E-68 T 21-04-2016 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 395 56.677 T 21-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 SUPERFAMILY SSF55973 245 395 9.12E-68 T 21-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 PANTHER PTHR11964 1 393 5.6E-266 T 21-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 1.0E-38 T 21-04-2016 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Gene3D G3DSA:3.30.300.10 144 245 1.0E-48 T 21-04-2016 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Pfam PF02772 S-adenosylmethionine synthetase, central domain 126 243 4.1E-49 T 21-04-2016 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Gene3D G3DSA:3.30.300.10 12 143 1.3E-42 T 21-04-2016 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 PIRSF PIRSF000497 1 396 1.8E-174 T 21-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 127 137 - T 21-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 Gene3D G3DSA:3.30.300.10 256 396 6.8E-69 T 21-04-2016 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 271 279 - T 21-04-2016 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 394 3.3E-177 T 21-04-2016 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS04260 dcf79a1370504223ac737c606bf256b8 397 SUPERFAMILY SSF55973 124 244 3.53E-52 T 21-04-2016 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: REACT_13433|UniPathway: UPA00315 HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 PANTHER PTHR12029 5 161 3.3E-72 T 21-04-2016 HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 Gene3D G3DSA:3.40.1280.10 3 167 3.5E-64 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 SUPERFAMILY SSF75217 5 156 9.81E-41 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 4 155 34.386 T 21-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 Pfam PF00588 SpoU rRNA Methylase family 5 146 9.1E-33 T 21-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 PANTHER PTHR12029:SF31 5 161 3.3E-72 T 21-04-2016 HSISS4_RS01270 c0396a0063c871d8bd8cc54323e05269 169 PIRSF PIRSF029256 3 158 5.2E-61 T 21-04-2016 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 PANTHER PTHR32332 1 320 1.1E-127 T 21-04-2016 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 PANTHER PTHR32332:SF20 1 320 1.1E-127 T 21-04-2016 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 Gene3D G3DSA:3.20.20.70 1 298 8.0E-75 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 SUPERFAMILY SSF51412 2 309 2.14E-75 T 21-04-2016 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 Pfam PF03060 Nitronate monooxygenase 2 302 4.7E-76 T 21-04-2016 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 HSISS4_RS01800 f9a528b2492d63ac1923b85e46c178b9 321 TIGRFAM TIGR03151 enACPred_II: putative enoyl-[acyl-carrier-protein] reductase II 2 311 3.0E-155 T 21-04-2016 IPR017569 Enoyl-(acyl-carrier-protein) reductase II, putative HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Gene3D G3DSA:3.40.309.10 315 406 1.6E-22 T 21-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Gene3D G3DSA:3.40.309.10 217 276 1.6E-22 T 21-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 PANTHER PTHR11496 366 861 1.8E-284 T 21-04-2016 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 SUPERFAMILY SSF56796 450 856 1.96E-113 T 21-04-2016 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 SUPERFAMILY SSF53720 12 455 1.07E-76 T 21-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 631 659 - T 21-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 PANTHER PTHR11496:SF79 366 861 1.8E-284 T 21-04-2016 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Pfam PF00171 Aldehyde dehydrogenase family 12 403 4.4E-22 T 21-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Pfam PF00465 Iron-containing alcohol dehydrogenase 459 847 9.2E-111 T 21-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Gene3D G3DSA:3.40.50.1970 452 642 5.2E-59 T 21-04-2016 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Gene3D G3DSA:3.40.605.10 12 208 2.1E-22 T 21-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 Gene3D G3DSA:1.20.1090.10 643 858 1.6E-65 T 21-04-2016 HSISS4_RS09155 1fa5b638b42cccb695330508e1794995 862 PIRSF PIRSF000111 1 862 0.0 T 21-04-2016 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00592+1.1.1.1|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00650+1.2.1.10|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7085|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7180|MetaCyc: PWY-7396 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 SUPERFAMILY SSF56024 314 509 6.73E-31 T 21-04-2016 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 PANTHER PTHR21248 59 524 6.3E-86 T 21-04-2016 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 56 524 1.3E-96 T 21-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 Pfam PF13091 PLD-like domain 365 490 2.5E-19 T 21-04-2016 IPR025202 Phospholipase D-like domain HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 Pfam PF13091 PLD-like domain 175 318 4.5E-11 T 21-04-2016 IPR025202 Phospholipase D-like domain HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 SMART SM00155 437 464 0.025 T 21-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 SMART SM00155 258 285 0.0032 T 21-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 Pfam PF13396 Phospholipase_D-nuclease N-terminal 59 95 3.8E-7 T 21-04-2016 IPR027379 Cardiolipin synthase N-terminal HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 PANTHER PTHR21248:SF5 59 524 6.3E-86 T 21-04-2016 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 Gene3D G3DSA:3.30.870.10 361 514 2.4E-27 T 21-04-2016 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 Gene3D G3DSA:3.30.870.10 153 355 4.3E-49 T 21-04-2016 HSISS4_RS05960 9aa1e64f5fa855e543b83fa919cf09fa 524 SUPERFAMILY SSF56024 146 322 4.71E-40 T 21-04-2016 HSISS4_RS01165 baf2fa1425d6e5e2dfe45c56fdfe9c89 658 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 295 655 4.7E-70 T 21-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like HSISS4_RS01165 baf2fa1425d6e5e2dfe45c56fdfe9c89 658 PANTHER PTHR30518:SF2 276 651 3.5E-71 T 21-04-2016 HSISS4_RS01165 baf2fa1425d6e5e2dfe45c56fdfe9c89 658 PANTHER PTHR30518 276 651 3.5E-71 T 21-04-2016 HSISS4_RS01165 baf2fa1425d6e5e2dfe45c56fdfe9c89 658 Pfam PF02618 YceG-like family 329 648 9.4E-74 T 21-04-2016 IPR003770 Uncharacterised protein family UPF0755, YceG-like HSISS4_RS01165 baf2fa1425d6e5e2dfe45c56fdfe9c89 658 Gene3D G3DSA:3.30.160.60 621 653 1.5E-8 T 21-04-2016 IPR013087 Zinc finger C2H2-type/integrase DNA-binding domain GO:0003676 HSISS4_RS01470 1e0de5d0261912e0b3a0cf099031494e 124 Pfam PF06115 Domain of unknown function (DUF956) 1 114 4.2E-42 T 21-04-2016 IPR010360 Protein of unknown function DUF956 HSISS4_RS01470 1e0de5d0261912e0b3a0cf099031494e 124 PIRSF PIRSF021265 1 122 3.6E-52 T 21-04-2016 IPR010360 Protein of unknown function DUF956 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 9 121 29.371 T 21-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 SUPERFAMILY SSF53137 10 119 3.74E-53 T 21-04-2016 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 9 121 1.6E-48 T 21-04-2016 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 PANTHER PTHR12899 9 121 4.5E-44 T 21-04-2016 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 10 121 2.6E-45 T 21-04-2016 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09270 35a8e3b12d7335179a6f1c81432ae8fd 121 Gene3D G3DSA:3.30.420.100 27 121 2.0E-39 T 21-04-2016 HSISS4_RS02455 b130cea85aa35eda1ab68752e45c8921 425 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 339 359 - T 21-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HSISS4_RS02455 b130cea85aa35eda1ab68752e45c8921 425 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 17 412 3.9E-120 T 21-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HSISS4_RS02455 b130cea85aa35eda1ab68752e45c8921 425 PANTHER PTHR11119 7 418 1.0E-151 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS02455 b130cea85aa35eda1ab68752e45c8921 425 Pfam PF00860 Permease family 20 390 2.4E-91 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS02455 b130cea85aa35eda1ab68752e45c8921 425 PANTHER PTHR11119:SF49 7 418 1.0E-151 T 21-04-2016 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 PANTHER PTHR21499 3 243 1.8E-112 T 21-04-2016 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 PANTHER PTHR21499:SF23 3 243 1.8E-112 T 21-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 Gene3D G3DSA:3.40.1160.10 2 238 7.4E-84 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 Pfam PF00696 Amino acid kinase family 7 217 1.8E-26 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 43.479 T 21-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 PIRSF PIRSF005650 1 245 8.1E-92 T 21-04-2016 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 SUPERFAMILY SSF53633 4 239 6.41E-72 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS02015 0b8520c62a3d2883140827adcf901311 245 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 1.4E-96 T 21-04-2016 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22|UniPathway: UPA00159 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 Gene3D G3DSA:1.10.287.990 20 89 1.3E-29 T 21-04-2016 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 163 170 - T 21-04-2016 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 SUPERFAMILY SSF54719 91 200 4.06E-45 T 21-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PRINTS PR01703 Manganese superoxide dismutase signature 161 173 4.8E-27 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.8E-27 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PRINTS PR01703 Manganese superoxide dismutase signature 124 132 4.8E-27 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.8E-27 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PRINTS PR01703 Manganese superoxide dismutase signature 72 85 4.8E-27 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 89 3.6E-30 T 21-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PANTHER PTHR11404 5 201 3.4E-99 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 SUPERFAMILY SSF46609 1 90 4.98E-34 T 21-04-2016 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 95 195 1.2E-41 T 21-04-2016 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS03580 231555361cc499f472bb880de9356a64 201 PIRSF PIRSF000349 1 201 3.4E-80 T 21-04-2016 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 PIRSF PIRSF000450 1 309 1.7E-149 T 21-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 SUPERFAMILY SSF52317 17 297 2.85E-96 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 302 7.4E-128 T 21-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 Pfam PF04204 Homoserine O-succinyltransferase 2 299 5.4E-136 T 21-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 PANTHER PTHR20919 2 313 1.5E-148 T 21-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 PANTHER PTHR20919:SF0 2 313 1.5E-148 T 21-04-2016 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 Hamap MF_00295 Homoserine O-succinyltransferase [metA]. 1 301 54.041 T 21-04-2016 IPR005697 Homoserine O-succinyltransferase GO:0005737|GO:0008899|GO:0019281 KEGG: 00270+2.3.1.46|KEGG: 00920+2.3.1.46|UniPathway: UPA00051 HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 Gene3D G3DSA:3.40.50.880 34 300 7.1E-120 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS04035 43451b1bb3db0451e0231687aab5dbe3 314 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 2.0E-142 T 21-04-2016 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.2 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 SUPERFAMILY SSF54686 1 135 2.35E-55 T 21-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 5.4E-49 T 21-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 21-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 21-04-2016 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.5E-37 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.5E-37 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.5E-37 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.5E-37 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 Gene3D G3DSA:3.90.1170.10 23 135 5.8E-54 T 21-04-2016 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.3E-57 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS09315 229b9bbbf896746d5fc5eadcf28ceaa5 137 PANTHER PTHR12220 1 135 8.2E-71 T 21-04-2016 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PANTHER PTHR22912 1 318 2.2E-119 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 6.4E-21 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 6.4E-21 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.4E-21 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 6.4E-21 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 6.4E-21 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 SUPERFAMILY SSF51905 1 315 1.73E-40 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PANTHER PTHR22912:SF158 1 318 2.2E-119 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 2.0E-20 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 112 130 2.0E-20 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 2.0E-20 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.0E-20 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 2.0E-20 T 21-04-2016 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 Hamap MF_01685 Ferredoxin--NADP reductase. 6 329 41.012 T 21-04-2016 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101|MetaCyc: PWY-7230 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 Gene3D G3DSA:3.50.50.60 129 248 2.1E-19 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 Gene3D G3DSA:3.50.50.60 4 127 4.4E-43 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 Gene3D G3DSA:3.50.50.60 249 327 4.4E-43 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06870 a80b748229d8a6fa3c3bd48836d81132 332 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 303 1.8E-33 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 SUPERFAMILY SSF55874 209 327 6.02E-15 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 Pfam PF07730 Histidine kinase 132 200 3.2E-16 T 21-04-2016 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 PANTHER PTHR24421 27 336 3.6E-53 T 21-04-2016 HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 PIRSF PIRSF037431 1 336 5.7E-127 T 21-04-2016 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 238 327 1.1E-5 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 SMART SM00387 236 330 5.4E-4 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 PANTHER PTHR24421:SF1 27 336 3.6E-53 T 21-04-2016 HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 Gene3D G3DSA:3.30.565.10 167 190 1.1E-10 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06900 4f4a6ddaa025194772b927d96b9756c0 336 Gene3D G3DSA:3.30.565.10 234 329 1.1E-10 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 Pfam PF00005 ABC transporter 20 167 2.7E-35 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 3 216 1.1E-89 T 21-04-2016 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 PANTHER PTHR24220 5 230 2.0E-121 T 21-04-2016 HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 PANTHER PTHR24220:SF470 5 230 2.0E-121 T 21-04-2016 HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 SMART SM00382 29 216 4.2E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 SUPERFAMILY SSF52540 3 224 8.87E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04445 1587f8523dbdac933495455c972a3c89 230 Gene3D G3DSA:3.40.50.300 2 222 2.1E-70 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 PANTHER PTHR30100 1 334 3.8E-124 T 21-04-2016 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 PANTHER PTHR30100:SF1 1 334 3.8E-124 T 21-04-2016 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 SUPERFAMILY SSF53659 1 328 1.27E-99 T 21-04-2016 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 4 329 1.1E-111 T 21-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 Pfam PF02504 Fatty acid synthesis protein 4 321 8.8E-104 T 21-04-2016 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 UniPathway: UPA00085 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 334 143.439 T 21-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 PIRSF PIRSF002465 1 334 1.9E-122 T 21-04-2016 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 UniPathway: UPA00085 HSISS4_RS00205 37a125ea934c98e7ae5537f297adcc04 334 Gene3D G3DSA:3.40.718.10 2 328 1.5E-129 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS02035 370e0fcec682cc832dc799500195ec49 422 Pfam PF01476 LysM domain 55 96 1.0E-8 T 21-04-2016 IPR018392 LysM domain HSISS4_RS02035 370e0fcec682cc832dc799500195ec49 422 SUPERFAMILY SSF54106 53 96 6.54E-9 T 21-04-2016 IPR018392 LysM domain HSISS4_RS02035 370e0fcec682cc832dc799500195ec49 422 SMART SM00257 54 98 1.4E-10 T 21-04-2016 IPR018392 LysM domain HSISS4_RS02035 370e0fcec682cc832dc799500195ec49 422 Gene3D G3DSA:3.10.350.10 53 96 1.4E-12 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03555 1918c55973de33876fd58186193326af 242 SUPERFAMILY SSF52540 1 221 3.89E-55 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03555 1918c55973de33876fd58186193326af 242 Pfam PF00005 ABC transporter 17 161 3.5E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03555 1918c55973de33876fd58186193326af 242 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS03555 1918c55973de33876fd58186193326af 242 Gene3D G3DSA:3.40.50.300 1 229 2.3E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03555 1918c55973de33876fd58186193326af 242 SMART SM00382 26 210 5.2E-12 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03555 1918c55973de33876fd58186193326af 242 PANTHER PTHR24220:SF581 3 233 6.7E-108 T 21-04-2016 HSISS4_RS03555 1918c55973de33876fd58186193326af 242 PANTHER PTHR24220 3 233 6.7E-108 T 21-04-2016 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 Hamap MF_00323 Ferrochelatase [hemH]. 2 294 28.164 T 21-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 ProSitePatterns PS00534 Ferrochelatase signature. 164 182 - T 21-04-2016 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 Gene3D G3DSA:3.40.50.1400 174 294 1.7E-32 T 21-04-2016 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 Gene3D G3DSA:3.40.50.1400 2 173 6.5E-32 T 21-04-2016 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 SUPERFAMILY SSF53800 1 295 2.78E-66 T 21-04-2016 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 Pfam PF00762 Ferrochelatase 3 293 3.3E-62 T 21-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 PANTHER PTHR11108 3 300 9.9E-75 T 21-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 HSISS4_RS05155 47ae9df0256ba52e60568997ef2b8fd4 364 TIGRFAM TIGR00109 hemH: ferrochelatase 2 293 3.2E-54 T 21-04-2016 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|UniPathway: UPA00252 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 SUPERFAMILY SSF47413 3 64 7.51E-18 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 PANTHER PTHR10245:SF26 1 65 2.3E-24 T 21-04-2016 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 Gene3D G3DSA:1.10.260.40 1 64 1.3E-25 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 PANTHER PTHR10245 1 65 2.3E-24 T 21-04-2016 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 Pfam PF01381 Helix-turn-helix 5 59 3.9E-18 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS09030 1295089d1e76ee7b0ac099280a05df86 65 SMART SM00530 4 59 2.0E-17 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 SUPERFAMILY SSF50037 82 151 2.29E-18 T 21-04-2016 IPR008988 Transcriptional repressor, C-terminal HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 PANTHER PTHR33238 72 155 3.9E-17 T 21-04-2016 HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 SMART SM00899 79 151 2.0E-20 T 21-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 SMART SM00899 1 71 0.0058 T 21-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 SUPERFAMILY SSF50037 5 69 7.1E-7 T 21-04-2016 IPR008988 Transcriptional repressor, C-terminal HSISS4_RS02865 e2429ab420da785bc8270f0ea9d65e7a 158 Pfam PF04023 FeoA domain 80 149 9.7E-15 T 21-04-2016 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 SUPERFAMILY SSF53335 91 305 1.61E-40 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 307 6.1E-112 T 21-04-2016 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 PIRSF PIRSF000401 2 309 2.1E-108 T 21-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 4 300 3.0E-73 T 21-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 Gene3D G3DSA:3.40.50.150 110 301 4.4E-46 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 4 307 34.599 T 21-04-2016 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 PANTHER PTHR18895 17 312 7.0E-90 T 21-04-2016 HSISS4_RS00760 9a200a2691a3fc163c7456c548530bf5 317 PANTHER PTHR18895:SF3 17 312 7.0E-90 T 21-04-2016 HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 Pfam PF02916 DNA polymerase processivity factor 72 187 3.1E-46 T 21-04-2016 IPR004190 DNA polymerase processivity factor GO:0006260 HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 PANTHER PTHR33392 226 431 1.9E-42 T 21-04-2016 HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 Gene3D G3DSA:3.40.190.10 108 194 8.6E-7 T 21-04-2016 HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 248 394 1.7E-41 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 248 394 1.8E-26 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS04585 b0e2203959f2e6fbfa7b8bbd200f5e77 486 SUPERFAMILY SSF53850 100 204 1.18E-5 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Pfam PF07687 Peptidase dimerisation domain 210 309 6.9E-14 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Gene3D G3DSA:3.30.70.360 213 322 6.1E-46 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 PANTHER PTHR11014:SF3 6 94 4.4E-169 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 PANTHER PTHR11014:SF3 134 404 4.4E-169 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 TIGRFAM TIGR01882 peptidase-T: peptidase T 3 404 4.6E-194 T 21-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 SUPERFAMILY SSF53187 6 213 4.02E-74 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 SUPERFAMILY SSF53187 325 404 4.02E-74 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 141 180 - T 21-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 PIRSF PIRSF037215 1 407 2.8E-182 T 21-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 SUPERFAMILY SSF55031 212 323 1.11E-40 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Gene3D G3DSA:3.40.630.10 325 405 3.7E-111 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Gene3D G3DSA:3.40.630.10 3 212 3.7E-111 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 PANTHER PTHR11014 6 94 4.4E-169 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 PANTHER PTHR11014 134 404 4.4E-169 T 21-04-2016 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Pfam PF01546 Peptidase family M20/M25/M40 142 404 1.4E-11 T 21-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 Hamap MF_00550 Peptidase T [pepT]. 3 407 56.626 T 21-04-2016 IPR010161 Peptidase M20B, tripeptide aminopeptidase GO:0005737|GO:0006518|GO:0008270|GO:0045148 HSISS4_RS04480 5d148a886e0b6456a5c56308ccab5822 407 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 77 86 - T 21-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 PIRSF PIRSF003314 1 332 8.7E-105 T 21-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 SUPERFAMILY SSF51395 19 327 3.57E-75 T 21-04-2016 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 PANTHER PTHR10578 15 210 6.4E-98 T 21-04-2016 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 PANTHER PTHR10578 226 326 6.4E-98 T 21-04-2016 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 PANTHER PTHR10578:SF3 15 210 6.4E-98 T 21-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 PANTHER PTHR10578:SF3 226 326 6.4E-98 T 21-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 Pfam PF01070 FMN-dependent dehydrogenase 159 316 1.5E-18 T 21-04-2016 IPR000262 FMN-dependent dehydrogenase GO:0016491 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 3 322 1.2E-106 T 21-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 323 32.808 T 21-04-2016 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 HSISS4_RS02600 feb827b949c57158695e5242cbd035a1 334 Gene3D G3DSA:3.20.20.70 19 320 5.9E-108 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 153 3.2E-13 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 181 3.2E-13 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 169 3.2E-13 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 SUPERFAMILY SSF52172 1 128 6.12E-30 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 Pfam PF00072 Response regulator receiver domain 4 114 5.6E-24 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 SUPERFAMILY SSF46894 126 199 4.76E-21 T 21-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 Gene3D G3DSA:1.10.10.10 144 198 2.6E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 PANTHER PTHR26402 1 199 1.7E-103 T 21-04-2016 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 PANTHER PTHR26402:SF580 1 199 1.7E-103 T 21-04-2016 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 Gene3D G3DSA:3.40.50.2300 1 143 5.9E-34 T 21-04-2016 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 138 193 7.7E-21 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 SMART SM00421 136 193 6.7E-25 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 153 180 - T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06070 8db13c5832f9aedf1eb229d2b7f4f057 200 SMART SM00448 1 114 9.6E-27 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 Pfam PF13419 Haloacid dehalogenase-like hydrolase 48 137 3.6E-13 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 29 139 7.6E-19 T 21-04-2016 IPR006549 HAD-superfamily hydrolase,subfamily IIIA HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 PANTHER PTHR19288 7 159 6.5E-34 T 21-04-2016 HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 SUPERFAMILY SSF56784 6 151 4.26E-27 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 6 167 5.0E-39 T 21-04-2016 IPR010021 HAD-superfamily phosphatase, YqeG-like HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 PANTHER PTHR19288:SF25 7 159 6.5E-34 T 21-04-2016 HSISS4_RS07840 d81c76be144a2a75c30d8e2de6e01a7e 175 Gene3D G3DSA:3.40.50.1000 11 157 1.4E-27 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 SUPERFAMILY SSF53756 5 344 2.88E-78 T 21-04-2016 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 PANTHER PTHR21015 6 354 1.9E-156 T 21-04-2016 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 PANTHER PTHR21015:SF27 6 354 1.9E-156 T 21-04-2016 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 7 146 4.5E-40 T 21-04-2016 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 191 336 3.8E-27 T 21-04-2016 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 7 353 23.427 T 21-04-2016 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 Gene3D G3DSA:3.40.50.2000 2 193 8.8E-55 T 21-04-2016 HSISS4_RS03625 b8260f837f92869bc496ca914f83163a 356 Gene3D G3DSA:3.40.50.2000 194 337 7.5E-23 T 21-04-2016 HSISS4_RS03060 50f9cfca1dc426a4b470ca2fcad2928f 312 Pfam PF03595 Voltage-dependent anion channel 9 289 4.4E-13 T 21-04-2016 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 HSISS4_RS03060 50f9cfca1dc426a4b470ca2fcad2928f 312 PANTHER PTHR37955 1 301 1.5E-32 T 21-04-2016 HSISS4_RS03060 50f9cfca1dc426a4b470ca2fcad2928f 312 PANTHER PTHR37955:SF1 1 301 1.5E-32 T 21-04-2016 HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 4 550 2.2E-151 T 21-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 352 403 4.0E-11 T 21-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 PANTHER PTHR11203:SF38 1 553 9.4E-268 T 21-04-2016 HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 SMART SM00849 16 211 5.2E-23 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 Hamap MF_01491 Ribonuclease J [rnj]. 1 552 39.135 T 21-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 PANTHER PTHR11203 1 553 9.4E-268 T 21-04-2016 HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 Pfam PF00753 Metallo-beta-lactamase superfamily 18 163 6.1E-14 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 Gene3D G3DSA:3.60.15.10 2 252 4.0E-67 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04185 3ee5807974647baaec29c1696645173b 553 SUPERFAMILY SSF56281 4 419 8.25E-73 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 PANTHER PTHR33498 1 414 5.9E-106 T 21-04-2016 HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 PANTHER PTHR33498:SF1 1 414 5.9E-106 T 21-04-2016 HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 Pfam PF01610 Transposase 157 400 1.1E-46 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 Gene3D G3DSA:1.10.10.60 106 139 1.3E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 6.8E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 SUPERFAMILY SSF46689 102 142 8.07E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS09695 39f29cd09ca7b397d028c5104e9aaeaf 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 2.5E-10 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 354 416 9.9E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 482 540 1.2E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 286 345 2.9E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 419 478 4.4E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 542 601 3.7E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 606 658 5.4E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 274 314 7.0E-9 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 324 366 6.4E-6 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 SUPERFAMILY SSF69360 253 464 4.78E-29 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 SUPERFAMILY SSF69360 457 645 1.11E-38 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Pfam PF01473 Putative cell wall binding repeat 474 486 0.062 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Pfam PF01473 Putative cell wall binding repeat 408 427 0.093 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Pfam PF01473 Putative cell wall binding repeat 596 614 0.016 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Pfam PF01473 Putative cell wall binding repeat 553 570 0.012 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 605 658 3.4E-12 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 484 534 2.0E-8 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 1.5E-6 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 540 604 7.0E-18 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 367 424 1.9E-12 T 21-04-2016 HSISS4_RS06515 41977ad6fbbc243312fab3fb3da34656 661 Gene3D G3DSA:2.10.270.10 425 483 1.1E-13 T 21-04-2016 HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 Gene3D G3DSA:1.10.10.60 106 139 1.3E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 PANTHER PTHR33498 1 414 1.1E-106 T 21-04-2016 HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 SUPERFAMILY SSF46689 102 142 8.07E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 Pfam PF01610 Transposase 157 400 4.5E-49 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 PANTHER PTHR33498:SF1 1 414 1.1E-106 T 21-04-2016 HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 2.5E-10 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS01045 aec9af418a0a87e82555c4b932d189b5 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 6.8E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 13 346 46.686 T 21-04-2016 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 Pfam PF01409 tRNA synthetases class II core domain (F) 97 346 4.0E-108 T 21-04-2016 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 SUPERFAMILY SSF46589 24 104 1.67E-19 T 21-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 SUPERFAMILY SSF55681 97 347 5.36E-82 T 21-04-2016 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 26 92 8.4E-24 T 21-04-2016 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 43 347 1.1E-107 T 21-04-2016 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 Gene3D G3DSA:3.30.930.10 22 347 7.1E-132 T 21-04-2016 HSISS4_RS05920 c3156bc7638d2567e8326a06a9ca6e47 347 PANTHER PTHR11538 97 347 4.2E-110 T 21-04-2016 HSISS4_RS05030 d68259456f367b4d2431a98486bd9f29 220 Pfam PF03787 RAMP superfamily 12 193 5.3E-20 T 21-04-2016 IPR005537 CRISPR type III-associated RAMP protein HSISS4_RS05030 d68259456f367b4d2431a98486bd9f29 220 PANTHER PTHR35579 5 201 2.7E-63 T 21-04-2016 HSISS4_RS05030 d68259456f367b4d2431a98486bd9f29 220 PANTHER PTHR35579:SF3 5 201 2.7E-63 T 21-04-2016 HSISS4_RS05030 d68259456f367b4d2431a98486bd9f29 220 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 5 195 7.0E-68 T 21-04-2016 IPR013412 CRISPR-associated RAMP Csm3 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 62 80 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 81 100 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 144 163 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 200 217 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 37 58 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00691 Adhesin B signature 293 311 6.5E-14 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 Pfam PF09223 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment 330 514 2.7E-80 T 21-04-2016 IPR015304 ZinT domain GO:0008270 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 SUPERFAMILY SSF50814 328 514 1.81E-75 T 21-04-2016 IPR011038 Calycin-like HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PANTHER PTHR30477:SF10 12 349 4.3E-104 T 21-04-2016 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 SUPERFAMILY SSF53807 32 310 4.07E-82 T 21-04-2016 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 Gene3D G3DSA:3.40.50.1980 33 194 1.5E-57 T 21-04-2016 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 310 6.7E-77 T 21-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PANTHER PTHR30477 12 349 4.3E-104 T 21-04-2016 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 Gene3D G3DSA:3.40.50.1980 195 310 1.2E-36 T 21-04-2016 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00690 Adhesin family signature 68 81 1.1E-9 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00690 Adhesin family signature 200 221 1.1E-9 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00690 Adhesin family signature 81 98 1.1E-9 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00690 Adhesin family signature 37 55 1.1E-9 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 PRINTS PR00690 Adhesin family signature 253 271 1.1E-9 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS05515 9f73770ddd87e3e2b8be7e0c3b8c3378 514 Gene3D G3DSA:2.40.128.20 326 514 4.5E-80 T 21-04-2016 IPR012674 Calycin HSISS4_RS08265 39a768e805f25727fa408e3f51c15c2c 148 PANTHER PTHR37299 1 148 3.1E-36 T 21-04-2016 HSISS4_RS08265 39a768e805f25727fa408e3f51c15c2c 148 Gene3D G3DSA:2.40.50.40 43 106 8.4E-17 T 21-04-2016 HSISS4_RS08265 39a768e805f25727fa408e3f51c15c2c 148 SMART SM00850 48 145 9.5E-29 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS08265 39a768e805f25727fa408e3f51c15c2c 148 Pfam PF04397 LytTr DNA-binding domain 51 144 4.7E-23 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 Pfam PF01926 50S ribosome-binding GTPase 166 231 5.0E-14 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 PANTHER PTHR11089:SF34 1 372 6.7E-200 T 21-04-2016 HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 Gene3D G3DSA:3.40.50.300 74 225 1.2E-29 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 PANTHER PTHR11089 1 372 6.7E-200 T 21-04-2016 HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 6 372 6.1E-154 T 21-04-2016 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH HSISS4_RS07835 5f727302391bc46549e98b345ebf7b48 372 SUPERFAMILY SSF52540 65 278 6.81E-32 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04335 4fb75bc6cefcd1aa7a5a88f43c7d5e65 216 Gene3D G3DSA:1.10.3720.10 13 212 2.8E-41 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04335 4fb75bc6cefcd1aa7a5a88f43c7d5e65 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 210 3.3E-19 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04335 4fb75bc6cefcd1aa7a5a88f43c7d5e65 216 SUPERFAMILY SSF161098 13 197 8.5E-37 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04335 4fb75bc6cefcd1aa7a5a88f43c7d5e65 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 102 1.5E-20 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS04335 4fb75bc6cefcd1aa7a5a88f43c7d5e65 216 PANTHER PTHR30614 9 216 4.5E-62 T 21-04-2016 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 106 1.5E-7 T 21-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 Gene3D G3DSA:1.10.540.10 13 106 1.2E-10 T 21-04-2016 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0008152|GO:0016627|GO:0050660|GO:0055114 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 Gene3D G3DSA:2.40.110.10 121 216 2.0E-11 T 21-04-2016 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 PANTHER PTHR10909 16 216 8.7E-16 T 21-04-2016 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 SUPERFAMILY SSF56645 12 216 1.19E-29 T 21-04-2016 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 HSISS4_RS03065 ced3e4addc851c345496c18c260768aa 354 PANTHER PTHR10909:SF305 16 216 8.7E-16 T 21-04-2016 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 136 1.0E-43 T 21-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 Pfam PF03652 Holliday junction resolvase 1 136 1.2E-42 T 21-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 PANTHER PTHR33317 1 138 2.9E-44 T 21-04-2016 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 SUPERFAMILY SSF53098 1 137 3.95E-42 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 SMART SM00732 1 103 2.0E-39 T 21-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 Gene3D G3DSA:3.30.420.140 1 137 2.5E-49 T 21-04-2016 IPR006641 YqgF/RNase H-like domain GO:0006139 HSISS4_RS09415 eae5fda0a0ba0eb6e4aae6718d061ac1 139 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 139 27.073 T 21-04-2016 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 PANTHER PTHR21349 4 102 6.4E-39 T 21-04-2016 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 25.332 T 21-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 1.3E-34 T 21-04-2016 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 21-04-2016 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 SUPERFAMILY SSF141091 4 103 2.62E-36 T 21-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 HSISS4_RS01910 a5c14084e4b91a0ec621022a427539c7 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 8.7E-37 T 21-04-2016 IPR028909 Ribosomal protein L21-like GO:0005840 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 Gene3D G3DSA:2.40.30.30 178 302 5.0E-39 T 21-04-2016 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 Pfam PF06574 FAD synthetase 13 165 6.4E-41 T 21-04-2016 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 Pfam PF01687 Riboflavin kinase 182 302 1.3E-31 T 21-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 85 5.5E-8 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 SUPERFAMILY SSF52374 16 178 4.22E-26 T 21-04-2016 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 SUPERFAMILY SSF82114 172 302 5.89E-44 T 21-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 PANTHER PTHR22749 1 303 2.9E-95 T 21-04-2016 IPR023468 Riboflavin kinase KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|UniPathway: UPA00276 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 PANTHER PTHR22749:SF3 1 303 2.9E-95 T 21-04-2016 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 SMART SM00904 181 303 1.8E-52 T 21-04-2016 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 PIRSF PIRSF004491 1 303 1.4E-94 T 21-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 Gene3D G3DSA:3.40.50.620 12 177 2.4E-48 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS04920 578a3a8515dc55a23493e1762ac04132 303 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 303 1.1E-76 T 21-04-2016 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|UniPathway: UPA00276|UniPathway: UPA00277 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.20.120.10 1412 1466 3.9E-5 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.20.120.10 1388 1411 3.6E-4 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF69360 1078 1234 7.85E-19 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1526 1594 1.6E-13 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 172 218 7.8E-5 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1467 1525 1.3E-12 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF51445 632 679 4.8E-28 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF51445 382 595 4.8E-28 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1092 1182 1.4E-12 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1194 1263 1.3E-7 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 4.9E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF69360 174 217 1.18E-5 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:3.20.20.80 870 982 8.9E-20 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Pfam PF01473 Putative cell wall binding repeat 1116 1133 0.074 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Pfam PF01473 Putative cell wall binding repeat 1253 1269 0.2 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Pfam PF01473 Putative cell wall binding repeat 1512 1529 0.25 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:3.20.20.80 377 687 9.7E-21 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF69360 1236 1426 1.29E-32 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Pfam PF02324 Glycosyl hydrolase family 70 277 1100 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF51445 858 1004 2.35E-27 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1303 1362 1.9E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1391 1451 3.6E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1521 1584 5.9E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1456 1520 3.9E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1323 1375 2.5E-6 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 Gene3D G3DSA:2.10.270.10 1264 1322 9.1E-19 T 21-04-2016 HSISS4_RS03990 349f96a76ec9a80b8ccbd51afcccbc99 1599 SUPERFAMILY SSF69360 1434 1594 1.88E-22 T 21-04-2016 HSISS4_RS05170 46d6c0773c253626af91d18d7f37ab81 166 Pfam PF13787 Protein of unknown function with HXXEE motif 8 114 1.3E-14 T 21-04-2016 IPR025671 Protein of unknown function with HXXEE motif HSISS4_RS06430 8938507270e21a46ae1764c47d61b685 419 PANTHER PTHR30489 1 418 1.7E-32 T 21-04-2016 HSISS4_RS06430 8938507270e21a46ae1764c47d61b685 419 Pfam PF12704 MacB-like periplasmic core domain 32 254 2.6E-8 T 21-04-2016 IPR025857 MacB-like periplasmic core domain HSISS4_RS06430 8938507270e21a46ae1764c47d61b685 419 Pfam PF02687 FtsX-like permease family 288 407 4.6E-14 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 SUPERFAMILY SSF53335 28 209 5.32E-32 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 PANTHER PTHR23417:SF14 1 210 7.5E-67 T 21-04-2016 HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 Gene3D G3DSA:3.40.50.150 30 153 3.6E-9 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 PANTHER PTHR23417 1 210 7.5E-67 T 21-04-2016 HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 28.889 T 21-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 Pfam PF02390 Putative methyltransferase 38 206 8.5E-48 T 21-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 HSISS4_RS07755 0e98aa092b5b967bcd3d2fc950c22064 213 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 209 4.9E-58 T 21-04-2016 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 UniPathway: UPA00989 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF51445 667 714 7.68E-36 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF51445 445 630 7.68E-36 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Pfam PF01473 Putative cell wall binding repeat 1367 1384 0.0012 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Pfam PF01473 Putative cell wall binding repeat 1156 1175 2.6E-4 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF69360 1145 1301 1.67E-19 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1249 1310 3.0E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1313 1374 3.4E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1376 1437 6.8E-24 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:2.10.270.10 1145 1222 7.8E-12 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 23 3.9E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF51445 888 1058 1.12E-26 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF69360 206 257 9.42E-7 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:3.20.20.80 440 619 5.4E-29 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:3.20.20.80 906 998 6.3E-20 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:3.20.20.80 658 719 5.4E-29 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:2.10.270.10 1319 1380 7.6E-18 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:2.10.270.10 1246 1318 6.9E-15 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:2.10.270.10 1381 1448 5.1E-17 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Gene3D G3DSA:2.10.270.10 207 257 9.9E-5 T 21-04-2016 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 Pfam PF02324 Glycosyl hydrolase family 70 323 1127 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS06685 0a7e8fd9fb11c46de9e012857a9b6cc0 1451 SUPERFAMILY SSF69360 1292 1448 2.43E-30 T 21-04-2016 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 Gene3D G3DSA:3.90.180.10 1 167 2.8E-62 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 SMART SM00829 10 335 8.3E-7 T 21-04-2016 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 133 3.1E-31 T 21-04-2016 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 21-04-2016 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 SUPERFAMILY SSF51735 136 304 3.04E-41 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 Pfam PF00107 Zinc-binding dehydrogenase 174 299 1.4E-26 T 21-04-2016 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 SUPERFAMILY SSF50129 1 171 2.28E-50 T 21-04-2016 IPR011032 GroES-like HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 PANTHER PTHR11695:SF498 13 339 4.1E-137 T 21-04-2016 HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 Gene3D G3DSA:3.40.50.720 168 285 2.0E-32 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05445 8ab63640ea77208b62957b7f41d527a1 339 PANTHER PTHR11695 13 339 4.1E-137 T 21-04-2016 IPR002085 Alcohol dehydrogenase superfamily, zinc-type GO:0008270|GO:0016491|GO:0055114 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PANTHER PTHR10906 6 427 8.0E-168 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 SUPERFAMILY SSF103491 5 418 1.01E-119 T 21-04-2016 IPR023201 SecY subunit domain HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PANTHER PTHR10906:SF2 6 427 8.0E-168 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 Pfam PF00344 SecY translocase 69 409 6.7E-100 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 Gene3D G3DSA:1.10.3370.10 6 428 4.0E-135 T 21-04-2016 IPR023201 SecY subunit domain HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 ProSitePatterns PS00755 Protein secY signature 1. 69 88 - T 21-04-2016 IPR030659 SecY conserved site HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 Hamap MF_01465 Protein translocase subunit SecY [secY]. 6 427 27.031 T 21-04-2016 IPR026593 Protein translocase subunit SecY HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 16 423 2.7E-133 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PIRSF PIRSF004557 2 430 9.6E-118 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 19 37 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 68 88 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 307 329 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 396 414 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 173 196 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 147 172 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 362 380 9.7E-90 T 21-04-2016 HSISS4_RS09250 2305afddc86c1a78f6de9ec67debe83d 431 PRINTS PR00303 Preprotein translocase SecY subunit signature 110 133 9.7E-90 T 21-04-2016 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 328 339 - T 21-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Pfam PF01268 Formate--tetrahydrofolate ligase 2 556 6.2E-264 T 21-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 PANTHER PTHR10025 1 555 0.0 T 21-04-2016 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 103 113 - T 21-04-2016 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Gene3D G3DSA:3.40.50.300 13 128 5.4E-145 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Gene3D G3DSA:3.40.50.300 248 441 5.4E-145 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 SUPERFAMILY SSF52540 4 554 6.49E-243 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Gene3D G3DSA:3.10.410.10 443 532 4.1E-38 T 21-04-2016 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 1 556 49.367 T 21-04-2016 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524|GO:0009396 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05675 a2bdff2b2c767cdbc49bc7c66d896718 556 Gene3D G3DSA:3.30.1510.10 129 246 8.5E-55 T 21-04-2016 HSISS4_RS07565 908226355fc45790c189b8cb6d3b5434 392 PANTHER PTHR23513:SF2 1 392 7.4E-139 T 21-04-2016 HSISS4_RS07565 908226355fc45790c189b8cb6d3b5434 392 SUPERFAMILY SSF103473 10 387 9.02E-26 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS07565 908226355fc45790c189b8cb6d3b5434 392 Gene3D G3DSA:1.20.1250.20 200 384 2.9E-14 T 21-04-2016 HSISS4_RS07565 908226355fc45790c189b8cb6d3b5434 392 Gene3D G3DSA:1.20.1250.20 36 186 6.3E-5 T 21-04-2016 HSISS4_RS07565 908226355fc45790c189b8cb6d3b5434 392 PANTHER PTHR23513 1 392 7.4E-139 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Pfam PF14490 Helix-hairpin-helix containing domain 147 237 1.4E-28 T 21-04-2016 IPR029493 RecD helicase-like helix-hairpin-helix domain HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Pfam PF13604 AAA domain 331 526 3.9E-44 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 SUPERFAMILY SSF52540 552 731 1.89E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 SUPERFAMILY SSF52540 447 513 1.89E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Gene3D G3DSA:3.40.50.300 661 745 2.3E-18 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Pfam PF13538 UvrD-like helicase C-terminal domain 659 705 6.4E-18 T 21-04-2016 IPR027785 UvrD-like helicase C-terminal domain HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 SMART SM00382 344 483 0.0042 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 SUPERFAMILY SSF52540 186 495 1.0E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 6 731 3.7E-277 T 21-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Gene3D G3DSA:3.40.50.300 290 517 1.1E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887 10 36 4.8E-104 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887 328 587 4.8E-104 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887 659 719 4.8E-104 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 3 734 28.086 T 21-04-2016 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887:SF284 10 36 4.8E-104 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887:SF284 328 587 4.8E-104 T 21-04-2016 HSISS4_RS08510 24d2826481a275eedb997521c8c9968c 834 PANTHER PTHR10887:SF284 659 719 4.8E-104 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF81665 234 328 2.22E-130 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF81665 10 123 2.22E-130 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF81665 672 886 2.22E-130 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SMART SM00831 9 82 3.7E-25 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Pfam PF00689 Cation transporting ATPase, C-terminus 707 883 1.0E-47 T 21-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 636 8.9E-24 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF81660 341 521 7.85E-50 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF81653 122 233 5.89E-31 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Pfam PF00690 Cation transporter/ATPase, N-terminus 11 77 2.1E-20 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:3.40.1110.10 325 524 3.7E-59 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:3.40.50.1000 527 581 7.9E-4 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PANTHER PTHR24093 782 891 0.0 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PANTHER PTHR24093 16 757 0.0 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Pfam PF00122 E1-E2 ATPase 91 325 8.0E-66 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 92 184 1.9E-20 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 224 359 4.8E-26 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 588 703 3.7E-34 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:1.20.1110.10 591 885 7.2E-119 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:1.20.1110.10 62 117 7.2E-119 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 476 494 7.1E-17 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 622 638 7.1E-17 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 654 679 7.1E-17 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 594 610 7.1E-17 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF56784 473 726 9.06E-58 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 SUPERFAMILY SSF56784 332 352 9.06E-58 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:2.70.150.10 118 233 1.4E-41 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 Gene3D G3DSA:2.70.150.10 23 61 1.4E-41 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 517 528 6.4E-38 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 6.4E-38 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 549 6.4E-38 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 170 184 6.4E-38 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 622 641 6.4E-38 T 21-04-2016 HSISS4_RS04420 d19ae57d18607d4270e07db5f1364231 894 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 646 658 6.4E-38 T 21-04-2016 HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 Gene3D G3DSA:3.40.50.300 1 206 1.3E-69 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 SUPERFAMILY SSF52540 1 207 4.42E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 Pfam PF00005 ABC transporter 18 162 9.1E-33 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 SMART SM00382 26 209 7.8E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05470 cd8a65b621f5b46e2df2f90dba3ad808 209 PANTHER PTHR24220 3 207 4.9E-82 T 21-04-2016 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 Gene3D G3DSA:1.10.286.10 3 51 1.7E-25 T 21-04-2016 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 SUPERFAMILY SSF55620 4 185 6.6E-77 T 21-04-2016 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 112 122 - T 21-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 PANTHER PTHR11109 2 185 1.5E-108 T 21-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 8 185 7.0E-77 T 21-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 63 79 - T 21-04-2016 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 Pfam PF01227 GTP cyclohydrolase I 8 184 9.8E-79 T 21-04-2016 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 Gene3D G3DSA:3.30.1130.10 56 185 2.1E-60 T 21-04-2016 HSISS4_RS07380 fad5e64b6647d9b03001e02c78d6eb16 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 3 185 42.251 T 21-04-2016 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|UniPathway: UPA00848 HSISS4_RS08815 a210e9c4b33c25807de644a0e88dff0d 438 SUPERFAMILY SSF55874 305 416 6.27E-5 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS08815 a210e9c4b33c25807de644a0e88dff0d 438 Pfam PF14501 GHKL domain 338 428 1.6E-10 T 21-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain HSISS4_RS08815 a210e9c4b33c25807de644a0e88dff0d 438 PANTHER PTHR40448 1 438 2.0E-23 T 21-04-2016 HSISS4_RS08815 a210e9c4b33c25807de644a0e88dff0d 438 PANTHER PTHR40448:SF1 1 438 2.0E-23 T 21-04-2016 HSISS4_RS07280 33aaac8d216b384bd9b969caef0cce3c 231 Pfam PF04172 LrgB-like family 15 227 5.2E-65 T 21-04-2016 IPR007300 CidB/LrgB family HSISS4_RS07280 33aaac8d216b384bd9b969caef0cce3c 231 PANTHER PTHR30249:SF5 3 229 7.8E-67 T 21-04-2016 HSISS4_RS07280 33aaac8d216b384bd9b969caef0cce3c 231 PANTHER PTHR30249 3 229 7.8E-67 T 21-04-2016 HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 SUPERFAMILY SSF51735 3 253 4.23E-52 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 Pfam PF00106 short chain dehydrogenase 3 210 1.9E-32 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 Gene3D G3DSA:3.40.50.720 3 253 4.8E-54 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.4E-19 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 1.4E-19 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 1.4E-19 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-19 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.4E-19 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 6.8E-6 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 6.8E-6 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 6.8E-6 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS05190 ac4b2b919ed7a8356221f4df8b72c80c 285 PANTHER PTHR24320 3 282 9.3E-74 T 21-04-2016 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 SUPERFAMILY SSF51445 4 376 2.08E-96 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 Pfam PF00128 Alpha amylase, catalytic domain 29 375 4.2E-29 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 Gene3D G3DSA:2.60.40.1180 399 480 4.4E-34 T 21-04-2016 IPR013780 Glycosyl hydrolase, all-beta HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 PIRSF PIRSF001021 1 483 2.7E-219 T 21-04-2016 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 PANTHER PTHR10357:SF168 3 109 7.9E-157 T 21-04-2016 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 PANTHER PTHR10357:SF168 131 479 7.9E-157 T 21-04-2016 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 SUPERFAMILY SSF51011 396 481 3.6E-33 T 21-04-2016 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 SMART SM00642 4 392 8.8E-67 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 PANTHER PTHR10357 3 109 7.9E-157 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 PANTHER PTHR10357 131 479 7.9E-157 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 Gene3D G3DSA:3.20.20.80 2 398 8.8E-74 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS07370 49c5e37258d06ac21960aeea9c7e6189 483 Pfam PF09154 Domain of unknown function (DUF1939) 423 480 6.2E-24 T 21-04-2016 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 Gene3D G3DSA:3.40.190.10 32 116 1.4E-37 T 21-04-2016 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 Gene3D G3DSA:3.40.190.10 221 256 1.4E-37 T 21-04-2016 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 37 254 2.2E-56 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 SMART SM00062 36 258 1.8E-54 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 PANTHER PTHR30614:SF15 29 260 6.6E-54 T 21-04-2016 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 SMART SM00079 36 257 1.7E-4 T 21-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 PANTHER PTHR30614 29 260 6.6E-54 T 21-04-2016 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 SUPERFAMILY SSF53850 1 256 1.66E-66 T 21-04-2016 HSISS4_RS07170 e69bd876190c339761d1281405f5e91a 265 Gene3D G3DSA:3.40.190.10 117 210 7.6E-22 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Pfam PF02491 SHS2 domain inserted in FTSA 85 160 1.2E-20 T 21-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Gene3D G3DSA:3.30.420.40 1 138 5.8E-52 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 PANTHER PTHR32432 1 399 3.6E-138 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Gene3D G3DSA:3.90.640.10 233 295 1.2E-24 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 SUPERFAMILY SSF53067 197 365 4.18E-38 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 457 27.725 T 21-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Pfam PF14450 Cell division protein FtsA 9 180 4.7E-9 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Pfam PF14450 Cell division protein FtsA 206 365 4.0E-17 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 SMART SM00842 7 194 1.9E-87 T 21-04-2016 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0007049 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Pfam PF11983 Membrane-attachment and polymerisation-promoting switch 377 458 1.2E-21 T 21-04-2016 IPR021873 Cell division protein FtsA, C-terminal HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 370 3.2E-99 T 21-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 PIRSF PIRSF003101 1 447 1.4E-128 T 21-04-2016 IPR020823 Cell division protein FtsA GO:0007049 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 PANTHER PTHR32432:SF4 1 399 3.6E-138 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 SUPERFAMILY SSF53067 6 195 1.65E-57 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Gene3D G3DSA:3.30.420.40 296 347 1.2E-17 T 21-04-2016 HSISS4_RS03635 dbf2243f0a54609a1c7e02539d3efb72 458 Gene3D G3DSA:3.30.420.40 195 232 1.2E-17 T 21-04-2016 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 PANTHER PTHR18895 37 273 4.8E-81 T 21-04-2016 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 Gene3D G3DSA:1.10.8.10 3 84 1.0E-8 T 21-04-2016 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 PANTHER PTHR18895:SF64 37 273 4.8E-81 T 21-04-2016 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 275 40.279 T 21-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 178 184 - T 21-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 Pfam PF05175 Methyltransferase small domain 106 193 2.8E-20 T 21-04-2016 IPR007848 Methyltransferase small domain GO:0008168 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 SUPERFAMILY SSF53335 5 272 3.09E-48 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 Gene3D G3DSA:3.40.50.150 86 273 2.2E-63 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 27 271 7.3E-81 T 21-04-2016 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 HSISS4_RS05795 ae023bc220e41eb3aaee47a6daf758bc 277 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 37 272 2.4E-63 T 21-04-2016 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 HSISS4_RS06700 06d9380de9fa4a725d411ce39be4e0d6 1113 TIGRFAM TIGR04224 ser_adhes_Nterm: serine-rich repeat adhesion glycoprotein 15 63 2.5E-17 T 21-04-2016 IPR026465 Serine-rich repeat adhesion glycoprotein HSISS4_RS06700 06d9380de9fa4a725d411ce39be4e0d6 1113 Pfam PF00746 Gram positive anchor 1073 1103 4.6E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS06700 06d9380de9fa4a725d411ce39be4e0d6 1113 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1074 1105 5.5E-7 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06405 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS02610 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS02125 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06640 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS06525 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 PANTHER PTHR32552 23 297 5.2E-45 T 21-04-2016 HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF00665 Integrase core domain 135 250 4.7E-26 T 21-04-2016 IPR001584 Integrase, catalytic core GO:0015074 HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:3.30.420.10 130 288 4.9E-27 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 Pfam PF13276 HTH-like domain 57 112 7.2E-11 T 21-04-2016 IPR025948 HTH-like domain HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 SUPERFAMILY SSF53098 130 290 1.29E-32 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05750 14c5b7556b4c424c4fc75c6b3fc3d711 321 Gene3D G3DSA:1.10.10.60 9 65 1.5E-4 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 636 1.3E-26 T 21-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 SMART SM00968 518 637 4.8E-39 T 21-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 SUPERFAMILY SSF52540 1 216 8.81E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 SUPERFAMILY SSF52540 1070 1156 8.81E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1173 22.94 T 21-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 PANTHER PTHR18937 1 485 0.0 T 21-04-2016 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 PANTHER PTHR18937 509 1174 0.0 T 21-04-2016 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 PIRSF PIRSF005719 1 1176 8.6E-290 T 21-04-2016 IPR024704 Structural maintenance of chromosomes protein HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1171 0.0 T 21-04-2016 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1164 2.6E-60 T 21-04-2016 IPR003395 RecF/RecN/SMC, N-terminal HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 SUPERFAMILY SSF75553 481 684 2.88E-51 T 21-04-2016 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 PANTHER PTHR18937:SF251 1 485 0.0 T 21-04-2016 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 PANTHER PTHR18937:SF251 509 1174 0.0 T 21-04-2016 HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 Gene3D G3DSA:3.40.50.300 1 163 4.6E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05935 4a4d9212fcc29261d594e5162e32df8b 1177 Gene3D G3DSA:3.40.50.300 1021 1174 4.6E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 PANTHER PTHR30614:SF15 1 226 7.6E-82 T 21-04-2016 HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 116 4.0E-21 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 Gene3D G3DSA:1.10.3720.10 12 221 7.0E-50 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 221 9.5E-24 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 SUPERFAMILY SSF161098 10 207 4.58E-43 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS02855 5a2bf9f3cfc3efd258c304a66754ca90 226 PANTHER PTHR30614 1 226 7.6E-82 T 21-04-2016 HSISS4_RS01305 7331a4a370a66c1e1ad86d015813a263 171 Pfam PF02293 AmiS/UreI family transporter 1 169 3.0E-59 T 21-04-2016 IPR003211 AmiS/UreI transporter GO:0006810|GO:0016020 HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 4 209 1.2E-92 T 21-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 49.479 T 21-04-2016 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183|UniPathway: UPA00574 HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 Gene3D G3DSA:3.40.50.2020 5 209 3.8E-87 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 SUPERFAMILY SSF53271 5 207 8.13E-74 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 3.6E-78 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS01615 4d099d050a302539d1944d4a2f8dbf06 209 PANTHER PTHR10285 5 198 7.2E-107 T 21-04-2016 HSISS4_RS08540 865ffb8bff5621fc1eaa67f37c57b35a 76 PANTHER PTHR41306 2 76 1.2E-19 T 21-04-2016 IPR009907 Protein of unknown function DUF1447 HSISS4_RS08540 865ffb8bff5621fc1eaa67f37c57b35a 76 Pfam PF07288 Protein of unknown function (DUF1447) 2 75 3.3E-30 T 21-04-2016 IPR009907 Protein of unknown function DUF1447 HSISS4_RS08540 865ffb8bff5621fc1eaa67f37c57b35a 76 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 75 2.0E-35 T 21-04-2016 IPR009907 Protein of unknown function DUF1447 HSISS4_RS08540 865ffb8bff5621fc1eaa67f37c57b35a 76 Hamap MF_01553 UPF0356 protein . 1 76 21.89 T 21-04-2016 IPR009907 Protein of unknown function DUF1447 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 Gene3D G3DSA:3.40.1390.30 1 112 1.9E-43 T 21-04-2016 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 PANTHER PTHR13799 1 262 1.3E-70 T 21-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 Gene3D G3DSA:3.40.1390.30 113 221 2.2E-38 T 21-04-2016 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 251 7.8E-58 T 21-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 SUPERFAMILY SSF102705 1 261 3.4E-78 T 21-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 PANTHER PTHR13799:SF13 1 262 1.3E-70 T 21-04-2016 HSISS4_RS03800 42926a7f7c38f2bc3d0897583429418e 262 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 239 2.2E-68 T 21-04-2016 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 PANTHER PTHR11904:SF9 1 269 7.4E-123 T 21-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 24 266 1.4E-104 T 21-04-2016 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 SUPERFAMILY SSF53167 4 269 1.27E-87 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 Gene3D G3DSA:3.40.50.1580 3 269 7.5E-103 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 Pfam PF01048 Phosphorylase superfamily 24 267 2.3E-50 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 21-04-2016 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 PIRSF PIRSF000477 2 269 7.8E-108 T 21-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 PANTHER PTHR11904 1 269 7.4E-123 T 21-04-2016 IPR001369 PNP/MTAP phosphorylase HSISS4_RS04565 413afa4a1792c1d58f98409a19560951 269 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 25 266 2.4E-103 T 21-04-2016 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|UniPathway: UPA00606 HSISS4_RS01625 8d26caf29eca0dcf5992051af9516898 149 PANTHER PTHR38448:SF2 3 127 3.3E-21 T 21-04-2016 HSISS4_RS01625 8d26caf29eca0dcf5992051af9516898 149 Gene3D G3DSA:1.20.1500.10 7 126 3.2E-20 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS01625 8d26caf29eca0dcf5992051af9516898 149 SUPERFAMILY SSF158622 6 127 1.7E-22 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS01625 8d26caf29eca0dcf5992051af9516898 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 13 117 4.6E-12 T 21-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA HSISS4_RS01625 8d26caf29eca0dcf5992051af9516898 149 PANTHER PTHR38448 3 127 3.3E-21 T 21-04-2016 HSISS4_RS06730 d85e8ca0287d4af6574aba4629979832 450 TIGRFAM TIGR02919 TIGR02919: accessory Sec system glycosyltransferase GtfB 1 432 2.0E-159 T 21-04-2016 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 HSISS4_RS06730 d85e8ca0287d4af6574aba4629979832 450 Hamap MF_01473 Glycosyltransferase stabilizing protein Gtf2 [gtf2]. 1 442 35.219 T 21-04-2016 IPR014268 Glycosyltransferase-stabilising protein Gtf2 GO:0031647 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 Gene3D G3DSA:3.40.50.1980 186 307 3.2E-44 T 21-04-2016 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 219 237 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 31 52 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 285 303 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 264 282 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 75 94 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 242 259 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 193 210 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 135 154 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00691 Adhesin B signature 56 74 5.0E-106 T 21-04-2016 IPR006129 Adhesin B GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 Pfam PF01297 Zinc-uptake complex component A periplasmic 34 304 1.5E-77 T 21-04-2016 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PANTHER PTHR30477:SF12 1 304 6.4E-133 T 21-04-2016 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 SUPERFAMILY SSF53807 16 307 7.36E-89 T 21-04-2016 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 Gene3D G3DSA:3.40.50.1980 19 185 2.7E-54 T 21-04-2016 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PANTHER PTHR30477 1 304 6.4E-133 T 21-04-2016 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 272 291 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 31 49 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 62 75 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 193 214 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 246 264 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS03545 1ac287b45d7535a5a1b321c04acba940 308 PRINTS PR00690 Adhesin family signature 75 92 1.5E-62 T 21-04-2016 IPR006128 Adhesion lipoprotein GO:0007155 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 SUPERFAMILY SSF52540 4 256 1.98E-80 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Gene3D G3DSA:2.40.50.100 362 376 7.9E-24 T 21-04-2016 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Gene3D G3DSA:2.40.50.100 251 297 7.9E-24 T 21-04-2016 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 PANTHER PTHR24220:SF151 5 309 4.4E-163 T 21-04-2016 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 SUPERFAMILY SSF50331 248 376 2.24E-27 T 21-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Pfam PF00005 ABC transporter 22 163 5.6E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 SMART SM00382 30 239 3.2E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Pfam PF03459 TOBE domain 316 366 1.2E-8 T 21-04-2016 IPR005116 Transport-associated OB, type 1 HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Gene3D G3DSA:3.40.50.300 3 246 2.2E-73 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 Gene3D G3DSA:2.40.50.140 298 360 4.4E-13 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS04810 7f088a7378446c6e80c03229eed275db 378 PANTHER PTHR24220 5 309 4.4E-163 T 21-04-2016 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 Pfam PF13167 GTP-binding GTPase N-terminal 26 113 3.8E-33 T 21-04-2016 IPR025121 GTPase HflX, N-terminal HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 351 9.7E-134 T 21-04-2016 IPR016496 GTPase HflX GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 2.4E-29 T 21-04-2016 IPR032305 GTP-binding protein, middle domain HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 Pfam PF01926 50S ribosome-binding GTPase 200 319 4.1E-18 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 PIRSF PIRSF006809 2 412 6.4E-139 T 21-04-2016 IPR016496 GTPase HflX GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 2.1E-7 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 2.1E-7 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 Hamap MF_00900 GTPase HflX [hflX]. 28 384 43.037 T 21-04-2016 IPR016496 GTPase HflX GO:0005525 HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 SUPERFAMILY SSF52540 199 395 1.41E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 Gene3D G3DSA:3.40.50.300 199 348 2.2E-30 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04000 6ed77eb59668cc42fb6bd7b9380f8565 412 PANTHER PTHR10229 9 380 7.8E-144 T 21-04-2016 IPR016496 GTPase HflX GO:0005525 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 PANTHER PTHR11735 1 126 5.6E-45 T 21-04-2016 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 204 2.5E-54 T 21-04-2016 IPR022496 tRNA threonylcarbamoyl adenosine modification protein YeaZ GO:0002949 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 PANTHER PTHR11735:SF11 1 126 5.6E-45 T 21-04-2016 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 Gene3D G3DSA:3.30.420.40 1 115 3.2E-40 T 21-04-2016 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 SUPERFAMILY SSF53067 106 202 4.66E-9 T 21-04-2016 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 SUPERFAMILY SSF53067 1 99 6.47E-28 T 21-04-2016 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 Pfam PF00814 Glycoprotease family 31 164 2.1E-28 T 21-04-2016 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 HSISS4_RS08535 9a6c62d5af8b7f7ef7806c2c36d35b54 228 Gene3D G3DSA:3.30.420.40 116 180 7.5E-5 T 21-04-2016 HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 Pfam PF07977 FabA-like domain 12 132 6.9E-36 T 21-04-2016 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 Gene3D G3DSA:3.10.129.10 2 139 4.9E-56 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 3 139 7.3E-61 T 21-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 PANTHER PTHR30272 2 141 1.7E-78 T 21-04-2016 HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 SUPERFAMILY SSF54637 5 139 3.5E-47 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS01825 6b8fb58fceefb938331c1f8cc408d838 141 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 3 141 33.616 T 21-04-2016 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWYG-321 HSISS4_RS08885 19a4d1b07cd3d6e90dfcee25d1caba1c 200 Gene3D G3DSA:3.40.50.360 1 179 1.1E-44 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS08885 19a4d1b07cd3d6e90dfcee25d1caba1c 200 Pfam PF03358 NADPH-dependent FMN reductase 1 145 4.9E-34 T 21-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HSISS4_RS08885 19a4d1b07cd3d6e90dfcee25d1caba1c 200 SUPERFAMILY SSF52218 1 176 6.29E-39 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS08885 19a4d1b07cd3d6e90dfcee25d1caba1c 200 PANTHER PTHR30543:SF6 1 196 8.6E-67 T 21-04-2016 HSISS4_RS08885 19a4d1b07cd3d6e90dfcee25d1caba1c 200 PANTHER PTHR30543 1 196 8.6E-67 T 21-04-2016 HSISS4_RS08915 815bc3a29fe277a7d42113ddfbba0371 224 PANTHER PTHR22936 12 218 9.1E-34 T 21-04-2016 IPR002610 Peptidase S54, rhomboid GO:0004252|GO:0006508|GO:0016021 HSISS4_RS08915 815bc3a29fe277a7d42113ddfbba0371 224 Pfam PF01694 Rhomboid family 56 193 1.2E-33 T 21-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HSISS4_RS08915 815bc3a29fe277a7d42113ddfbba0371 224 SUPERFAMILY SSF144091 7 193 1.27E-37 T 21-04-2016 HSISS4_RS08915 815bc3a29fe277a7d42113ddfbba0371 224 Gene3D G3DSA:1.20.1540.10 7 191 2.5E-38 T 21-04-2016 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 HSISS4_RS01440 901c9ee9906f27a87a1b3b1fdd6e1c68 159 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 81.439 T 21-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HSISS4_RS01440 901c9ee9906f27a87a1b3b1fdd6e1c68 159 PANTHER PTHR30455:SF2 2 156 2.3E-66 T 21-04-2016 HSISS4_RS01440 901c9ee9906f27a87a1b3b1fdd6e1c68 159 Pfam PF03477 ATP cone domain 50 136 1.6E-17 T 21-04-2016 IPR005144 ATP-cone domain HSISS4_RS01440 901c9ee9906f27a87a1b3b1fdd6e1c68 159 PANTHER PTHR30455 2 156 2.3E-66 T 21-04-2016 HSISS4_RS01440 901c9ee9906f27a87a1b3b1fdd6e1c68 159 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 145 1.6E-59 T 21-04-2016 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 SUPERFAMILY SSF53927 208 515 4.71E-120 T 21-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Gene3D G3DSA:3.40.140.20 239 358 8.1E-47 T 21-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Gene3D G3DSA:3.40.140.20 366 505 3.7E-56 T 21-04-2016 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 PANTHER PTHR11692:SF2 1 515 1.4E-297 T 21-04-2016 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 PIRSF PIRSF000414 1 515 3.2E-207 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 PANTHER PTHR11692 1 515 1.4E-297 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 448 1.8E-114 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 SUPERFAMILY SSF52335 2 194 2.29E-69 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 SMART SM00798 134 450 9.6E-187 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Pfam PF02142 MGS-like domain 14 128 3.7E-25 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 515 3.0E-212 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Gene3D G3DSA:3.40.50.1380 2 186 1.2E-82 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 SMART SM00851 14 129 1.7E-50 T 21-04-2016 IPR011607 Methylglyoxal synthase-like domain HSISS4_RS00240 2d70b81e6d0d4214d66f0ba3c8ff8246 515 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 515 44.273 T 21-04-2016 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00074 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 SUPERFAMILY SSF52467 188 356 1.73E-32 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Gene3D G3DSA:3.40.50.1220 190 352 1.8E-32 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 PANTHER PTHR18968 1 556 4.0E-273 T 21-04-2016 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 173 4.0E-49 T 21-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 PANTHER PTHR18968:SF129 1 556 4.0E-273 T 21-04-2016 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 427 446 - T 21-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Gene3D G3DSA:3.40.50.970 361 547 1.3E-64 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 SUPERFAMILY SSF52518 365 548 7.58E-62 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 194 329 3.8E-24 T 21-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 SUPERFAMILY SSF52518 6 179 1.18E-49 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 390 538 1.5E-44 T 21-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 Gene3D G3DSA:3.40.50.970 6 180 1.1E-59 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05310 77c96ba0672a64f50a3bcd3defcaba60 558 TIGRFAM TIGR02418 acolac_catab: acetolactate synthase, catabolic 9 549 1.7E-279 T 21-04-2016 IPR012782 Acetolactate synthase, catabolic GO:0000287|GO:0003984|GO:0030976|GO:0034077 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00626 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 SUPERFAMILY SSF69360 493 735 6.2E-25 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 564 659 3.4E-11 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 266 362 3.0E-10 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 746 833 1.9E-11 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 1029 1081 6.6E-11 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 926 982 8.6E-7 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 497 563 4.4E-14 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 SUPERFAMILY SSF69360 389 543 1.73E-22 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 SUPERFAMILY SSF69360 1018 1160 2.12E-18 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 660 717 4.2E-5 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 844 892 5.9E-13 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 560 623 4.8E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 852 907 4.5E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 190 251 3.4E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 689 738 6.2E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 927 983 1.4E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 500 559 2.1E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 404 468 3.8E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1032 1091 1.5E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 1086 1177 1.5E-6 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 180 265 2.5E-15 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 Gene3D G3DSA:2.10.270.10 386 480 7.0E-16 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 SUPERFAMILY SSF69360 181 362 1.96E-24 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 SUPERFAMILY SSF69360 747 978 7.85E-25 T 21-04-2016 HSISS4_RS06555 eb6731b4d37885ba0395b9d6552c6b88 1187 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 3.7E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS00630 2922569d77fae86f8d4b1260006106f1 278 Pfam PF04203 Sortase family 86 245 6.9E-16 T 21-04-2016 IPR005754 Sortase family HSISS4_RS00630 2922569d77fae86f8d4b1260006106f1 278 TIGRFAM TIGR03064 sortase_srtB: sortase, SrtB family 14 250 8.3E-70 T 21-04-2016 IPR009835 Sortase B family HSISS4_RS00630 2922569d77fae86f8d4b1260006106f1 278 SUPERFAMILY SSF63817 48 243 5.89E-35 T 21-04-2016 IPR023365 Sortase domain HSISS4_RS00630 2922569d77fae86f8d4b1260006106f1 278 Gene3D G3DSA:2.40.260.10 21 257 7.7E-59 T 21-04-2016 IPR023365 Sortase domain HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 PANTHER PTHR21139 1 251 2.4E-120 T 21-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 Gene3D G3DSA:3.20.20.70 3 250 5.4E-102 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 SUPERFAMILY SSF51351 3 250 5.89E-90 T 21-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 Pfam PF00121 Triosephosphate isomerase 6 247 5.8E-91 T 21-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 242 7.3E-60 T 21-04-2016 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 166 176 - T 21-04-2016 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS02290 f97259930550d6a3b73724074a56029b 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 251 39.722 T 21-04-2016 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|UniPathway: UPA00109|UniPathway: UPA00138 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 PANTHER PTHR30425:SF6 1 304 8.9E-156 T 21-04-2016 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 SUPERFAMILY SSF161098 23 294 2.43E-39 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 296 2.2E-26 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 Gene3D G3DSA:1.10.3720.10 27 302 7.3E-46 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 PANTHER PTHR30425 1 304 8.9E-156 T 21-04-2016 HSISS4_RS04890 8b42ab1a8d4bc32cc03f7dfdfc37afda 304 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 20 298 1.4E-85 T 21-04-2016 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 Gene3D G3DSA:1.20.58.370 161 183 4.3E-4 T 21-04-2016 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 SUPERFAMILY SSF160964 161 196 2.09E-5 T 21-04-2016 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 PANTHER PTHR30193:SF17 156 448 1.4E-77 T 21-04-2016 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 PANTHER PTHR30193 156 448 1.4E-77 T 21-04-2016 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 SUPERFAMILY SSF161098 202 437 4.06E-51 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 Gene3D G3DSA:1.10.3720.10 213 442 4.1E-56 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04820 6cd87efd0d5fe106c0c29950a483f9d1 452 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 234 440 1.0E-22 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 PANTHER PTHR24220:SF66 8 233 7.1E-51 T 21-04-2016 HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 Gene3D G3DSA:3.40.50.300 3 235 1.2E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 Pfam PF00005 ABC transporter 24 176 1.1E-20 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 PANTHER PTHR24220 8 233 7.1E-51 T 21-04-2016 HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 SUPERFAMILY SSF52540 5 237 9.02E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 SMART SM00382 33 221 2.5E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05220 189a3d11c269c411a7cf509976000cc0 278 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00950 24ed0b621cda45f3445755ed28abec4f 112 SMART SM01323 1 83 2.0E-9 T 21-04-2016 IPR003849 Preprotein translocase YajC HSISS4_RS00950 24ed0b621cda45f3445755ed28abec4f 112 Pfam PF02699 Preprotein translocase subunit 4 74 8.3E-10 T 21-04-2016 IPR003849 Preprotein translocase YajC HSISS4_RS03030 494c6def3fdc13160ff6c07feebf642e 112 PANTHER PTHR41254 1 110 1.2E-32 T 21-04-2016 HSISS4_RS03030 494c6def3fdc13160ff6c07feebf642e 112 Hamap MF_01526 UPF0342 protein . 1 112 18.012 T 21-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA HSISS4_RS03030 494c6def3fdc13160ff6c07feebf642e 112 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 4 107 1.3E-24 T 21-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA HSISS4_RS03030 494c6def3fdc13160ff6c07feebf642e 112 SUPERFAMILY SSF158622 3 110 2.88E-33 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS03030 494c6def3fdc13160ff6c07feebf642e 112 Gene3D G3DSA:1.20.1500.10 1 110 6.0E-42 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 Gene3D G3DSA:1.10.10.10 185 243 1.5E-7 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 SUPERFAMILY SSF46785 171 260 2.03E-40 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 4 257 1.1E-118 T 21-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 PIRSF PIRSF011572 1 261 2.6E-116 T 21-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 PANTHER PTHR40062 2 261 8.9E-118 T 21-04-2016 HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 Pfam PF06018 CodY GAF-like domain 3 182 1.1E-73 T 21-04-2016 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 261 128.172 T 21-04-2016 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 HSISS4_RS07910 dd6e517b680d642eaf160e84da1f0e79 261 Pfam PF08222 CodY helix-turn-helix domain 202 260 3.9E-38 T 21-04-2016 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Gene3D G3DSA:3.40.50.970 9 186 5.6E-72 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Gene3D G3DSA:3.40.50.970 362 560 4.5E-69 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 PANTHER PTHR18968:SF116 3 563 2.0E-299 T 21-04-2016 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 SUPERFAMILY SSF52518 370 561 1.71E-62 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 538 1.8E-45 T 21-04-2016 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Gene3D G3DSA:3.40.50.1220 194 359 1.2E-61 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 SUPERFAMILY SSF52518 6 186 1.63E-60 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 21-04-2016 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 11 176 6.9E-57 T 21-04-2016 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 SUPERFAMILY SSF52467 193 358 3.82E-58 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 335 1.4E-47 T 21-04-2016 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 11 562 1.1E-234 T 21-04-2016 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09115 563187902850c256faafc7b7d708224f 566 PANTHER PTHR18968 3 563 2.0E-299 T 21-04-2016 HSISS4_RS01550 91ca6992abbddf632ea8d4fb53095a8f 98 PANTHER PTHR34215 1 94 5.0E-30 T 21-04-2016 HSISS4_RS01550 91ca6992abbddf632ea8d4fb53095a8f 98 PANTHER PTHR34215:SF1 1 94 5.0E-30 T 21-04-2016 HSISS4_RS01550 91ca6992abbddf632ea8d4fb53095a8f 98 Pfam PF04296 Protein of unknown function (DUF448) 10 83 2.5E-22 T 21-04-2016 IPR007393 Domain of unknown function DUF448 HSISS4_RS01550 91ca6992abbddf632ea8d4fb53095a8f 98 Gene3D G3DSA:3.30.1230.10 2 96 5.2E-32 T 21-04-2016 IPR007393 Domain of unknown function DUF448 HSISS4_RS01550 91ca6992abbddf632ea8d4fb53095a8f 98 SUPERFAMILY SSF64376 5 96 3.14E-27 T 21-04-2016 IPR007393 Domain of unknown function DUF448 HSISS4_RS05835 216d568a83c4f4f6dab81336b1b766df 420 Pfam PF01566 Natural resistance-associated macrophage protein 36 281 7.7E-10 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 SMART SM00437 270 530 3.2E-110 T 21-04-2016 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 SMART SM00493 31 131 6.2E-29 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Pfam PF01131 DNA topoisomerase 156 568 5.2E-131 T 21-04-2016 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:3.40.50.140 30 162 2.5E-44 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Hamap MF_00952 DNA topoisomerase 1 [topA]. 31 653 55.606 T 21-04-2016 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:2.70.20.10 343 476 5.2E-34 T 21-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:2.70.20.10 212 341 1.1E-32 T 21-04-2016 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 SUPERFAMILY SSF57783 593 633 1.39E-12 T 21-04-2016 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 SUPERFAMILY SSF56712 31 609 6.15E-192 T 21-04-2016 IPR023405 DNA topoisomerase, type IA, core domain HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 307 329 - T 21-04-2016 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PANTHER PTHR11390:SF27 29 708 0.0 T 21-04-2016 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:1.10.460.10 477 581 5.4E-58 T 21-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:1.10.460.10 163 210 5.4E-58 T 21-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:1.10.460.10 640 644 5.4E-58 T 21-04-2016 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 33 631 4.4E-245 T 21-04-2016 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 678 712 0.012 T 21-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 598 633 1.1E-13 T 21-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 637 673 3.0E-13 T 21-04-2016 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Pfam PF01751 Toprim domain 33 141 3.2E-30 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 Gene3D G3DSA:3.30.65.10 596 639 3.0E-18 T 21-04-2016 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 SMART SM00436 132 220 1.4E-51 T 21-04-2016 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 190 208 1.8E-35 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 396 412 1.8E-35 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 493 507 1.8E-35 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 320 329 1.8E-35 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 105 118 1.8E-35 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05380 e5851a4e193f3634b25b341b5510ed69 714 PANTHER PTHR11390 29 708 0.0 T 21-04-2016 IPR000380 DNA topoisomerase, type IA GO:0003677|GO:0003917|GO:0006265 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 Gene3D G3DSA:3.40.50.300 332 564 5.8E-60 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 SMART SM00382 359 546 1.8E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 Pfam PF00005 ABC transporter 350 500 6.4E-29 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 SUPERFAMILY SSF90123 4 315 6.28E-62 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 Pfam PF00664 ABC transporter transmembrane region 16 284 7.5E-38 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 PANTHER PTHR24221:SF190 1 579 2.1E-144 T 21-04-2016 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 SUPERFAMILY SSF52540 331 570 3.55E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 PANTHER PTHR24221 1 579 2.1E-144 T 21-04-2016 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05770 1009eb2efff8bef82845ac40cb55cdba 579 Gene3D G3DSA:1.20.1560.10 2 314 2.7E-57 T 21-04-2016 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SUPERFAMILY SSF81886 576 788 1.28E-46 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Gene3D G3DSA:3.40.50.300 399 565 1.3E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Pfam PF07517 SecA DEAD-like domain 10 381 1.6E-108 T 21-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SMART SM00958 222 338 3.3E-41 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SUPERFAMILY SSF81767 225 348 5.36E-34 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Gene3D G3DSA:1.10.3060.10 604 777 5.5E-30 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SMART SM00957 2 382 9.2E-207 T 21-04-2016 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 TIGRFAM TIGR03714 secA2: accessory Sec system translocase SecA2 11 766 0.0 T 21-04-2016 IPR022490 Protein translocase subunit SecA2 GO:0015031|GO:0015450 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SUPERFAMILY SSF52540 348 395 1.06E-65 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SUPERFAMILY SSF52540 10 222 1.06E-65 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Gene3D G3DSA:3.90.1440.10 226 347 1.1E-34 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 SUPERFAMILY SSF52540 398 562 9.14E-43 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Pfam PF07516 SecA Wing and Scaffold domain 578 774 6.1E-32 T 21-04-2016 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PANTHER PTHR30612 12 779 3.6E-250 T 21-04-2016 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Hamap MF_01382 Protein translocase subunit SecA [secA]. 1 779 16.584 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Gene3D G3DSA:3.40.50.300 349 396 5.4E-99 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Gene3D G3DSA:3.40.50.300 11 222 5.4E-99 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 319 341 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 356 373 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 91 105 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 53 77 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 107 117 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 393 406 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 PRINTS PR00906 SecA protein signature 164 184 1.8E-54 T 21-04-2016 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 HSISS4_RS06740 ff76bab8410581c0b6366bc2ff7e8540 791 Pfam PF01043 SecA preprotein cross-linking domain 227 338 3.9E-25 T 21-04-2016 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 HSISS4_RS09130 90d9d357b9d8c125f0c1d433b0a662cb 121 PANTHER PTHR34297:SF2 1 121 5.8E-49 T 21-04-2016 HSISS4_RS09130 90d9d357b9d8c125f0c1d433b0a662cb 121 PANTHER PTHR34297 1 121 5.8E-49 T 21-04-2016 HSISS4_RS09130 90d9d357b9d8c125f0c1d433b0a662cb 121 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 5.0E-32 T 21-04-2016 IPR005531 Alkaline shock protein Asp23 HSISS4_RS01920 7ec6d302ae7a6a37fa102161f4239d71 231 Pfam PF13302 Acetyltransferase (GNAT) domain 48 174 3.9E-15 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS01920 7ec6d302ae7a6a37fa102161f4239d71 231 Gene3D G3DSA:3.40.630.30 18 214 3.7E-54 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01920 7ec6d302ae7a6a37fa102161f4239d71 231 PANTHER PTHR13256:SF22 7 221 8.2E-83 T 21-04-2016 HSISS4_RS01920 7ec6d302ae7a6a37fa102161f4239d71 231 SUPERFAMILY SSF55729 24 198 5.91E-39 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01920 7ec6d302ae7a6a37fa102161f4239d71 231 PANTHER PTHR13256 7 221 8.2E-83 T 21-04-2016 HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 SUPERFAMILY SSF52540 3 225 5.45E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 SMART SM00382 34 222 3.9E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 Gene3D G3DSA:3.40.50.300 2 223 2.3E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 Pfam PF00005 ABC transporter 25 173 1.3E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 PANTHER PTHR24220 5 252 1.3E-107 T 21-04-2016 HSISS4_RS06140 c24775808066e9149f58d8766bb957e8 252 PANTHER PTHR24220:SF494 5 252 1.3E-107 T 21-04-2016 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 PANTHER PTHR22911 1 294 1.5E-67 T 21-04-2016 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 PANTHER PTHR22911:SF65 1 294 1.5E-67 T 21-04-2016 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 SUPERFAMILY SSF103481 42 148 3.53E-11 T 21-04-2016 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 Pfam PF00892 EamA-like transporter family 6 144 4.1E-19 T 21-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 Pfam PF00892 EamA-like transporter family 157 290 2.7E-16 T 21-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HSISS4_RS07845 c59af64e664858f427bff492d25ee543 305 SUPERFAMILY SSF103481 198 293 9.81E-7 T 21-04-2016 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Gene3D G3DSA:3.40.50.20 1 116 6.7E-31 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 PIRSF PIRSF039102 1 345 1.0E-102 T 21-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 PANTHER PTHR23132 1 344 4.2E-151 T 21-04-2016 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Gene3D G3DSA:3.30.470.20 208 334 3.8E-49 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Gene3D G3DSA:3.30.470.20 117 134 3.8E-49 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 279 307 - T 21-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 PANTHER PTHR23132:SF8 1 344 4.2E-151 T 21-04-2016 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 94 105 - T 21-04-2016 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Pfam PF01820 D-ala D-ala ligase N-terminus 6 116 1.2E-25 T 21-04-2016 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Pfam PF07478 D-ala D-ala ligase C-terminus 135 333 5.9E-75 T 21-04-2016 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Gene3D G3DSA:3.30.1490.20 146 207 8.0E-25 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 SUPERFAMILY SSF56059 127 334 5.13E-59 T 21-04-2016 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 6 334 2.6E-100 T 21-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 337 38.914 T 21-04-2016 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07620 78fb57eb5bd4d0cac462667c5b1711e7 348 SUPERFAMILY SSF52440 3 126 2.88E-31 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 SUPERFAMILY SSF52402 8 215 2.37E-52 T 21-04-2016 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 SMART SM00977 345 402 1.9E-6 T 21-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 PANTHER PTHR11807:SF2 1 408 7.8E-64 T 21-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 PANTHER PTHR11807 1 408 7.8E-64 T 21-04-2016 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 20 193 1.5E-52 T 21-04-2016 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 345 388 6.6E-12 T 21-04-2016 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 Gene3D G3DSA:3.40.50.620 13 165 2.3E-16 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 2 289 22.419 T 21-04-2016 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 HSISS4_RS00055 948a8ed038b104259321abef4bd602f4 421 Pfam PF01171 PP-loop family 20 188 1.4E-52 T 21-04-2016 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 PANTHER PTHR11203:SF22 3 558 8.8E-241 T 21-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 Gene3D G3DSA:3.60.15.10 10 258 4.9E-78 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 SUPERFAMILY SSF56281 14 426 4.82E-92 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 410 1.3E-9 T 21-04-2016 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 PANTHER PTHR11203 3 558 8.8E-241 T 21-04-2016 HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 SMART SM00849 24 218 3.2E-24 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 Pfam PF00753 Metallo-beta-lactamase superfamily 22 170 1.4E-17 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 Hamap MF_01491 Ribonuclease J [rnj]. 7 558 45.427 T 21-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 367 395 - T 21-04-2016 IPR001587 Ribonuclease J, conserved site HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 PIRSF PIRSF004803 3 558 1.6E-223 T 21-04-2016 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 HSISS4_RS08545 fe2fe59a6f96b6972142e1000e6aa9c0 560 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 13 555 2.2E-197 T 21-04-2016 IPR004613 Ribonuclease J GO:0003723|GO:0046872 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Pfam PF02690 Na+/Pi-cotransporter 147 260 2.7E-19 T 21-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Pfam PF02690 Na+/Pi-cotransporter 18 153 4.0E-47 T 21-04-2016 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: REACT_15518 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 TIGRFAM TIGR00704 NaPi_cotrn_rel: Na/Pi-cotransporter II-related protein 10 315 2.1E-72 T 21-04-2016 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein GO:0016020 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Gene3D G3DSA:1.20.58.220 333 438 6.6E-14 T 21-04-2016 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 SUPERFAMILY SSF109755 334 538 4.92E-41 T 21-04-2016 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Gene3D G3DSA:1.20.58.220 439 539 4.2E-14 T 21-04-2016 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 PANTHER PTHR10010 1 455 8.1E-117 T 21-04-2016 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 PANTHER PTHR10010:SF26 1 455 8.1E-117 T 21-04-2016 HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Pfam PF01895 PhoU domain 349 432 8.6E-10 T 21-04-2016 IPR026022 PhoU domain HSISS4_RS02360 06e32040d827b353386b5560f271aeb6 543 Pfam PF01895 PhoU domain 456 537 3.5E-9 T 21-04-2016 IPR026022 PhoU domain HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 Pfam PF00164 Ribosomal protein S12/S23 2 136 8.9E-39 T 21-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PIRSF PIRSF002133 1 137 1.8E-47 T 21-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 55 70 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 123 135 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 107 123 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 71 90 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 40 55 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PRINTS PR01034 Ribosomal protein S12 signature 90 107 3.32E-57 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 136 2.2E-66 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 Gene3D G3DSA:2.40.50.140 1 136 1.7E-61 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 PANTHER PTHR11652 1 129 5.6E-71 T 21-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 39.659 T 21-04-2016 IPR005679 Ribosomal protein S12, bacteria GO:0003735|GO:0006412|GO:0015935 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 21-04-2016 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08595 4fa5ef4bf4d44c76c6946f607ade8ab4 137 SUPERFAMILY SSF50249 2 136 1.37E-47 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 Gene3D G3DSA:1.20.200.10 91 356 1.2E-89 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 6.5E-25 T 21-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PANTHER PTHR11444 3 428 8.2E-172 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 3.5E-9 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 3.5E-9 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 3.5E-9 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 21-04-2016 IPR020557 Fumarate lyase, conserved site GO:0003824 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PANTHER PTHR11444:SF2 3 428 8.2E-172 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 1.6E-170 T 21-04-2016 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 SUPERFAMILY SSF48557 3 427 3.77E-136 T 21-04-2016 IPR008948 L-Aspartase-like GO:0003824 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 Pfam PF00206 Lyase 7 286 8.7E-70 T 21-04-2016 IPR022761 Fumarate lyase, N-terminal HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 Gene3D G3DSA:1.10.40.30 357 428 3.6E-33 T 21-04-2016 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 SMART SM00998 349 429 6.6E-40 T 21-04-2016 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|UniPathway: UPA00074|UniPathway: UPA00075 HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 Gene3D G3DSA:1.10.275.10 2 90 8.0E-36 T 21-04-2016 IPR024083 Fumarase/histidase, N-terminal HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.3E-25 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.3E-25 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.3E-25 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS00280 5735a29fbc454ecf64f8a9937a1339a9 432 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.3E-25 T 21-04-2016 IPR000362 Fumarate lyase family HSISS4_RS04290 3243b04c30bd6a4d83ae80a36fe0ae5e 588 SUPERFAMILY SSF49265 474 553 2.2E-8 T 21-04-2016 IPR003961 Fibronectin type III GO:0005515 HSISS4_RS04290 3243b04c30bd6a4d83ae80a36fe0ae5e 588 Pfam PF08757 CotH protein 133 463 4.2E-72 T 21-04-2016 IPR014867 Spore coat protein CotH HSISS4_RS04290 3243b04c30bd6a4d83ae80a36fe0ae5e 588 Gene3D G3DSA:2.60.40.10 481 554 3.2E-7 T 21-04-2016 IPR013783 Immunoglobulin-like fold HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 SUPERFAMILY SSF54211 191 327 2.69E-35 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 21-04-2016 IPR014762 DNA mismatch repair, conserved site HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 SMART SM00853 447 589 2.4E-43 T 21-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 PANTHER PTHR10073 4 645 9.6E-167 T 21-04-2016 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Gene3D G3DSA:3.30.565.10 3 203 2.5E-74 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Gene3D G3DSA:3.30.230.10 204 326 8.8E-37 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 SUPERFAMILY SSF55874 3 214 1.06E-54 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 SMART SM01340 209 327 1.4E-50 T 21-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Pfam PF08676 MutL C terminal dimerisation domain 445 589 9.9E-40 T 21-04-2016 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 326 3.9E-35 T 21-04-2016 IPR013507 DNA mismatch repair protein, C-terminal GO:0005524|GO:0006298|GO:0030983 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 126 6.2E-13 T 21-04-2016 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 SUPERFAMILY SSF118116 443 631 9.29E-52 T 21-04-2016 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 629 27.271 T 21-04-2016 IPR020667 DNA mismatch repair protein, MutL GO:0006298 HSISS4_RS00320 99203d3122e16fe1eb3aa96a96d80538 645 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 307 1.2E-100 T 21-04-2016 IPR002099 DNA mismatch repair protein family GO:0005524|GO:0006298|GO:0030983 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 Gene3D G3DSA:1.10.287.40 1 105 3.5E-23 T 21-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PRINTS PR00981 Seryl-tRNA synthetase signature 263 275 1.8E-34 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PRINTS PR00981 Seryl-tRNA synthetase signature 315 328 1.8E-34 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PRINTS PR00981 Seryl-tRNA synthetase signature 350 366 1.8E-34 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PRINTS PR00981 Seryl-tRNA synthetase signature 275 288 1.8E-34 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PRINTS PR00981 Seryl-tRNA synthetase signature 332 348 1.8E-34 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PIRSF PIRSF001529 1 425 4.2E-185 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 6.9E-30 T 21-04-2016 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 SUPERFAMILY SSF46589 1 113 1.46E-28 T 21-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 421 42.76 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 Gene3D G3DSA:3.30.930.10 106 420 5.7E-145 T 21-04-2016 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 PANTHER PTHR11778 1 425 7.0E-219 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 222 399 1.6E-36 T 21-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 416 1.2E-176 T 21-04-2016 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: REACT_71|UniPathway: UPA00906 HSISS4_RS01465 8c66f03ba730e20cf949cd04764283c3 425 SUPERFAMILY SSF55681 117 419 2.49E-109 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SMART SM00116 100 150 1.8E-6 T 21-04-2016 IPR000644 CBS domain HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SMART SM00116 163 211 4.3E-9 T 21-04-2016 IPR000644 CBS domain HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 PANTHER PTHR11911 1 287 1.3E-247 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 PANTHER PTHR11911 305 491 1.3E-247 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SMART SM01240 11 479 0.0 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 Pfam PF00571 CBS domain 160 206 1.1E-7 T 21-04-2016 IPR000644 CBS domain HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 Pfam PF00571 CBS domain 100 145 4.0E-7 T 21-04-2016 IPR000644 CBS domain HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 PANTHER PTHR11911:SF6 1 287 1.3E-247 T 21-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 PANTHER PTHR11911:SF6 305 491 1.3E-247 T 21-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SUPERFAMILY SSF51412 7 94 1.44E-121 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SUPERFAMILY SSF51412 222 483 1.44E-121 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 12 460 3.1E-195 T 21-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 PIRSF PIRSF000130 3 493 1.4E-209 T 21-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 Gene3D G3DSA:3.20.20.70 9 491 7.7E-202 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 SUPERFAMILY SSF54631 99 210 3.54E-29 T 21-04-2016 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 12 479 9.1E-160 T 21-04-2016 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 Reactome: REACT_1698 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 12 492 83.913 T 21-04-2016 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: REACT_1698|UniPathway: UPA00601 HSISS4_RS09690 4be6701fe300f8b3fbaf5754f34d4be4 493 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 300 312 - T 21-04-2016 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 Reactome: REACT_1698 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 404 1.3E-10 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 SUPERFAMILY SSF55874 258 407 1.16E-18 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 SMART SM00387 296 407 2.9E-7 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 PANTHER PTHR24423 188 392 5.5E-28 T 21-04-2016 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 PANTHER PTHR24423 1 8 5.5E-28 T 21-04-2016 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 Gene3D G3DSA:1.10.287.130 189 238 1.9E-10 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 SMART SM00388 190 252 7.0E-10 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 SUPERFAMILY SSF47384 185 251 5.89E-11 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 Pfam PF00512 His Kinase A (phospho-acceptor) domain 191 251 2.0E-9 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS02010 6a94848749c25e8d7c5cf079e05ad330 407 Gene3D G3DSA:3.30.565.10 239 407 8.3E-21 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 ProSitePatterns PS01229 Hypothetical cof family signature 2. 626 648 - T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 563 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 433 447 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 574 584 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 649 661 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 282 296 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 626 645 2.4E-28 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Pfam PF00122 E1-E2 ATPase 204 423 1.1E-68 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Pfam PF00702 haloacid dehalogenase-like hydrolase 429 640 3.0E-47 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 SUPERFAMILY SSF56784 431 451 1.28E-56 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 SUPERFAMILY SSF56784 486 731 1.28E-56 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Gene3D G3DSA:3.40.50.1000 555 695 4.1E-57 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Gene3D G3DSA:3.40.50.1000 404 449 4.1E-57 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PANTHER PTHR24093 101 734 7.3E-231 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 435 441 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PANTHER PTHR24093:SF50 101 734 7.3E-231 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Gene3D G3DSA:2.60.40.420 9 88 9.8E-6 T 21-04-2016 IPR008972 Cupredoxin HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 SUPERFAMILY SSF81665 184 236 9.42E-15 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 SUPERFAMILY SSF81665 333 425 9.42E-15 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 SUPERFAMILY SSF81653 236 332 1.7E-26 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 172 734 1.4E-189 T 21-04-2016 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Gene3D G3DSA:3.40.1110.10 453 554 1.0E-18 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 204 713 2.9E-89 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00943 Copper-transporting ATPase signature 604 621 2.7E-6 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00943 Copper-transporting ATPase signature 355 369 2.7E-6 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00943 Copper-transporting ATPase signature 222 240 2.7E-6 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00943 Copper-transporting ATPase signature 699 713 2.7E-6 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 PRINTS PR00943 Copper-transporting ATPase signature 202 221 2.7E-6 T 21-04-2016 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Gene3D G3DSA:2.70.150.10 170 332 6.8E-32 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 Pfam PF13473 Cupredoxin-like domain 10 97 7.9E-11 T 21-04-2016 IPR028096 EfeO-type cupredoxin-like domain HSISS4_RS05135 58dd7a645a6791a7f2df9a2a0f45822f 740 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 153 734 1.2E-185 T 21-04-2016 HSISS4_RS07200 9dc71ff36b9965e5c9e0928693d7cc3c 311 Pfam PF02517 CAAX protease self-immunity 156 246 3.2E-13 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS07200 9dc71ff36b9965e5c9e0928693d7cc3c 311 PANTHER PTHR39430 32 310 1.9E-41 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PANTHER PTHR30523:SF0 5 356 0.0 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 134 145 - T 21-04-2016 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PANTHER PTHR30523 382 940 0.0 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PANTHER PTHR30523:SF0 382 940 0.0 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 SUPERFAMILY SSF51621 17 341 6.12E-283 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 SUPERFAMILY SSF51621 377 940 6.12E-283 T 21-04-2016 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 594 606 - T 21-04-2016 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 769 795 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 243 258 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 592 612 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 634 663 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 133 146 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 186 202 4.6E-47 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 PANTHER PTHR30523 5 356 0.0 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 Pfam PF00311 Phosphoenolpyruvate carboxylase 129 940 1.1E-253 T 21-04-2016 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 Gene3D G3DSA:1.20.1440.90 369 433 9.0E-30 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 Gene3D G3DSA:1.20.1440.90 272 335 9.0E-30 T 21-04-2016 HSISS4_RS03570 e1c378013102c74c3a1d991493b63c14 940 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 8 940 17.202 T 21-04-2016 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 HSISS4_RS00960 1e3278f935aa1e0fa046150d7ed7c8be 264 Pfam PF01148 Cytidylyltransferase family 3 261 5.8E-71 T 21-04-2016 HSISS4_RS00960 1e3278f935aa1e0fa046150d7ed7c8be 264 PANTHER PTHR13773 1 261 2.1E-64 T 21-04-2016 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 SUPERFAMILY SSF53633 9 264 7.46E-63 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PANTHER PTHR11063 3 263 6.7E-72 T 21-04-2016 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PANTHER PTHR11063:SF12 3 263 6.7E-72 T 21-04-2016 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 Hamap MF_00456 Glutamate 5-kinase [proB]. 9 266 35.732 T 21-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PIRSF PIRSF000729 4 267 6.4E-85 T 21-04-2016 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 ProSitePatterns PS00902 Glutamate 5-kinase signature. 215 232 - T 21-04-2016 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PRINTS PR00474 Glutamate 5-kinase family signature 217 237 3.7E-49 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PRINTS PR00474 Glutamate 5-kinase family signature 46 60 3.7E-49 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PRINTS PR00474 Glutamate 5-kinase family signature 80 108 3.7E-49 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PRINTS PR00474 Glutamate 5-kinase family signature 120 141 3.7E-49 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 PRINTS PR00474 Glutamate 5-kinase family signature 156 183 3.7E-49 T 21-04-2016 IPR001057 Glutamate/acetylglutamate kinase GO:0006561 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 Pfam PF00696 Amino acid kinase family 9 240 1.1E-37 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 TIGRFAM TIGR01027 proB: glutamate 5-kinase 9 266 1.1E-85 T 21-04-2016 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|UniPathway: UPA00098 HSISS4_RS08190 67e4e7bf5aaf68bfa7cb397ed50c6174 267 Gene3D G3DSA:3.40.1160.10 9 263 1.7E-52 T 21-04-2016 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: REACT_13 HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 TIGRFAM TIGR00337 PyrG: CTP synthase 1 528 1.2E-250 T 21-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 SUPERFAMILY SSF52317 290 532 6.21E-76 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 SUPERFAMILY SSF52540 1 270 1.78E-125 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 Gene3D G3DSA:3.40.50.880 289 533 8.2E-98 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 Pfam PF06418 CTP synthase N-terminus 3 267 4.4E-129 T 21-04-2016 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 Hamap MF_01227 CTP synthase [pyrG]. 2 533 51.273 T 21-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 Gene3D G3DSA:3.40.50.300 1 284 3.3E-140 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 Pfam PF00117 Glutamine amidotransferase class-I 302 527 5.2E-57 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS00745 44c85a56693fe4aba88d393336701d7c 534 PANTHER PTHR11550 1 531 0.0 T 21-04-2016 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: REACT_1698|UniPathway: UPA00159 HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 18 162 1.4E-42 T 21-04-2016 IPR005864 ATPase, F0 complex, subunit B, bacterial GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 Pfam PF00430 ATP synthase B/B' CF(0) 13 142 3.1E-28 T 21-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 Gene3D G3DSA:1.20.5.620 69 123 4.7E-5 T 21-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 Hamap MF_01398 ATP synthase subunit b [atpF]. 3 162 12.717 T 21-04-2016 IPR002146 ATPase, F0 complex, subunit B/B', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 PANTHER PTHR33445 7 165 7.2E-37 T 21-04-2016 HSISS4_RS02250 93fffe6a658dc4a0aae20c24cf1ee765 165 SUPERFAMILY SSF81573 69 127 8.11E-8 T 21-04-2016 IPR028987 F-type ATP synthase subunit B-like, membrane domain HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 Pfam PF00406 Adenylate kinase 5 185 4.0E-55 T 21-04-2016 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 TIGRFAM TIGR01351 adk: adenylate kinase 2 208 8.6E-73 T 21-04-2016 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PRINTS PR00094 Adenylate kinase signature 4 17 2.6E-30 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PRINTS PR00094 Adenylate kinase signature 32 46 2.6E-30 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PRINTS PR00094 Adenylate kinase signature 156 171 2.6E-30 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PRINTS PR00094 Adenylate kinase signature 82 98 2.6E-30 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PRINTS PR00094 Adenylate kinase signature 173 187 2.6E-30 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 Hamap MF_00235 Adenylate kinase [adk]. 1 209 49.279 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 Gene3D G3DSA:3.40.50.300 1 208 4.0E-69 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 SUPERFAMILY SSF52540 1 208 1.96E-38 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09245 f741d4c45a1662a2e88080a804865e32 212 PANTHER PTHR23359 1 208 5.0E-89 T 21-04-2016 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|MetaCyc: PWY-7219|UniPathway: UPA00588 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 SUPERFAMILY SSF102114 29 231 1.44E-26 T 21-04-2016 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 PANTHER PTHR30352:SF9 4 248 1.4E-122 T 21-04-2016 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 PANTHER PTHR30352 4 248 1.4E-122 T 21-04-2016 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 Gene3D G3DSA:3.80.30.10 77 252 5.8E-67 T 21-04-2016 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 ProSitePatterns PS01087 Radical activating enzymes signature. 24 45 - T 21-04-2016 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 Pfam PF13353 4Fe-4S single cluster domain 22 142 3.3E-16 T 21-04-2016 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 13 249 8.6E-97 T 21-04-2016 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 HSISS4_RS07930 2c2928d5d528da5e5228066ba38bdad6 266 Pfam PF04055 Radical SAM superfamily 30 193 5.2E-31 T 21-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 PIRSF PIRSF006230 1 276 2.7E-97 T 21-04-2016 IPR016478 GTPase, MTG1 HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 Pfam PF01926 50S ribosome-binding GTPase 124 190 5.3E-15 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 4 274 1.2E-107 T 21-04-2016 IPR019991 GTP-binding protein, ribosome biogenesis HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 SUPERFAMILY SSF52540 10 191 6.94E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 Gene3D G3DSA:1.10.1580.10 181 268 2.5E-25 T 21-04-2016 IPR023179 GTP-binding protein, orthogonal bundle domain HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 Gene3D G3DSA:3.40.50.300 16 178 4.8E-39 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05400 eada2e85749a018b9dfabce753e3c18f 284 PANTHER PTHR11089 4 277 4.2E-72 T 21-04-2016 HSISS4_RS07905 08b9110eb1ed7c910150a4a7f94d02ad 183 PANTHER PTHR11080 1 182 2.6E-44 T 21-04-2016 HSISS4_RS07905 08b9110eb1ed7c910150a4a7f94d02ad 183 Pfam PF00857 Isochorismatase family 4 178 1.2E-35 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS07905 08b9110eb1ed7c910150a4a7f94d02ad 183 SUPERFAMILY SSF52499 2 181 8.11E-50 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS07905 08b9110eb1ed7c910150a4a7f94d02ad 183 Gene3D G3DSA:3.40.50.850 2 182 2.0E-47 T 21-04-2016 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 317 1.5E-41 T 21-04-2016 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 12 310 5.2E-124 T 21-04-2016 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PANTHER PTHR11540 4 327 5.2E-153 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PRINTS PR00086 L-lactate dehydrogenase signature 9 33 3.7E-44 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PRINTS PR00086 L-lactate dehydrogenase signature 36 60 3.7E-44 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PRINTS PR00086 L-lactate dehydrogenase signature 122 142 3.7E-44 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PRINTS PR00086 L-lactate dehydrogenase signature 146 164 3.7E-44 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PRINTS PR00086 L-lactate dehydrogenase signature 176 189 3.7E-44 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 Gene3D G3DSA:3.90.110.10 150 317 2.6E-63 T 21-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PANTHER PTHR11540:SF3 4 327 5.2E-153 T 21-04-2016 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 SUPERFAMILY SSF56327 149 316 1.28E-57 T 21-04-2016 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 PIRSF PIRSF000102 4 324 8.9E-107 T 21-04-2016 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 Gene3D G3DSA:3.40.50.720 3 149 1.6E-50 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 7 317 45.196 T 21-04-2016 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 178 184 - T 21-04-2016 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|UniPathway: UPA00554 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 9 148 2.0E-45 T 21-04-2016 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 HSISS4_RS05860 0c3b8fa44e76817646b0f172d117a087 328 SUPERFAMILY SSF51735 4 150 5.32E-50 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 4 291 3.3E-101 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Gene3D G3DSA:3.40.1380.10 68 194 3.8E-40 T 21-04-2016 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 277 290 - T 21-04-2016 IPR023632 ATPase, F1 complex, gamma subunit conserved site HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Pfam PF00231 ATP synthase 4 291 2.2E-86 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Gene3D G3DSA:1.10.287.80 206 239 1.3E-26 T 21-04-2016 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Gene3D G3DSA:1.10.287.80 20 61 1.3E-26 T 21-04-2016 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 291 32.308 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 PRINTS PR00126 ATP synthase gamma subunit signature 269 290 1.9E-35 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 PRINTS PR00126 ATP synthase gamma subunit signature 238 257 1.9E-35 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 PRINTS PR00126 ATP synthase gamma subunit signature 76 95 1.9E-35 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 PRINTS PR00126 ATP synthase gamma subunit signature 169 186 1.9E-35 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 Gene3D G3DSA:1.10.287.80 240 286 7.2E-28 T 21-04-2016 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 PANTHER PTHR11693 1 292 2.4E-97 T 21-04-2016 IPR000131 ATPase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02265 f5e2843dbe5b523bde8d6d51b48ec123 292 SUPERFAMILY SSF52943 4 291 4.58E-87 T 21-04-2016 IPR023633 ATPase, F1 complex, gamma subunit domain HSISS4_RS04090 2bafaf3a65e9d20db685cb04944a6667 291 Gene3D G3DSA:3.40.50.1110 50 286 5.2E-58 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS04090 2bafaf3a65e9d20db685cb04944a6667 291 SUPERFAMILY SSF52266 49 282 7.75E-42 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS04090 2bafaf3a65e9d20db685cb04944a6667 291 PANTHER PTHR30383 52 226 6.1E-25 T 21-04-2016 HSISS4_RS04090 2bafaf3a65e9d20db685cb04944a6667 291 PANTHER PTHR30383 242 288 6.1E-25 T 21-04-2016 HSISS4_RS04090 2bafaf3a65e9d20db685cb04944a6667 291 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 56 272 3.3E-28 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 SUPERFAMILY SSF51735 3 155 9.54E-51 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 PANTHER PTHR10174 47 344 4.6E-71 T 21-04-2016 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 PIRSF PIRSF000148 2 347 2.2E-122 T 21-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 137 328 1.3E-51 T 21-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 342 36.43 T 21-04-2016 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 Gene3D G3DSA:3.40.50.720 2 140 2.0E-61 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 5 342 3.5E-133 T 21-04-2016 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|UniPathway: UPA00034|UniPathway: UPA00050|UniPathway: UPA00051 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 118 1.4E-31 T 21-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 SUPERFAMILY SSF55347 127 329 4.46E-67 T 21-04-2016 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 PANTHER PTHR10174:SF2 47 344 4.6E-71 T 21-04-2016 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 Gene3D G3DSA:3.30.360.10 141 325 5.5E-73 T 21-04-2016 HSISS4_RS05950 34d24e647a3c205407be3c48c94b5b41 358 SMART SM00859 4 119 4.4E-43 T 21-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 Pfam PF00155 Aminotransferase class I and II 33 385 2.6E-61 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 PANTHER PTHR11751 15 390 3.0E-184 T 21-04-2016 HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 PANTHER PTHR11751:SF391 15 390 3.0E-184 T 21-04-2016 HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 SUPERFAMILY SSF53383 6 388 6.47E-99 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 Gene3D G3DSA:3.40.640.10 48 257 1.5E-55 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS02160 55654f45bd1fa77aaa231a2b54fb548a 393 Gene3D G3DSA:3.90.1150.10 258 388 5.3E-38 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 PANTHER PTHR24220:SF86 5 227 5.3E-98 T 21-04-2016 HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 SUPERFAMILY SSF52540 3 224 4.87E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 PANTHER PTHR24220 5 227 5.3E-98 T 21-04-2016 HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 Pfam PF00005 ABC transporter 24 172 2.9E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 Gene3D G3DSA:3.40.50.300 2 224 1.5E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01080 7ebbde72e7bfc9023d6c2c4ebf881e46 227 SMART SM00382 33 220 6.3E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03725 86d8df24ef2fcbdceaf0ba4a6e4735c5 246 SUPERFAMILY SSF53474 3 242 1.16E-24 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03725 86d8df24ef2fcbdceaf0ba4a6e4735c5 246 Gene3D G3DSA:3.40.50.1820 1 243 3.1E-24 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03725 86d8df24ef2fcbdceaf0ba4a6e4735c5 246 Pfam PF00756 Putative esterase 11 238 8.1E-15 T 21-04-2016 IPR000801 Putative esterase HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 PANTHER PTHR20941:SF1 14 266 4.8E-113 T 21-04-2016 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 PANTHER PTHR20941 14 266 4.8E-113 T 21-04-2016 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 14 262 2.3E-100 T 21-04-2016 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614|UniPathway: UPA00077 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 14 29 - T 21-04-2016 IPR000489 Pterin-binding domain GO:0042558 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 Pfam PF00809 Pterin binding enzyme 15 250 2.4E-84 T 21-04-2016 IPR000489 Pterin-binding domain GO:0042558 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 Gene3D G3DSA:3.20.20.20 11 264 1.1E-105 T 21-04-2016 IPR000489 Pterin-binding domain GO:0042558 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 SUPERFAMILY SSF51717 10 263 3.66E-93 T 21-04-2016 IPR011005 Dihydropteroate synthase-like GO:0044237 HSISS4_RS07375 299693a27291e03f6d7c04028ff302d1 266 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 48 61 - T 21-04-2016 IPR000489 Pterin-binding domain GO:0042558 HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 Gene3D G3DSA:3.40.50.1240 1 185 7.3E-46 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 21-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 SUPERFAMILY SSF53254 1 184 5.11E-48 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 PANTHER PTHR23029 4 188 4.0E-51 T 21-04-2016 HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 PANTHER PTHR23029:SF38 4 188 4.0E-51 T 21-04-2016 HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 SMART SM00855 3 152 1.2E-20 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS04680 03d4c9d53936085aa69993575376b0f2 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 187 4.2E-39 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 PANTHER PTHR18901 7 175 3.0E-20 T 21-04-2016 HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 175 1.0E-21 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 Gene3D G3DSA:1.10.150.240 16 79 3.3E-29 T 21-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 Gene3D G3DSA:3.40.50.1000 2 15 1.1E-29 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 Gene3D G3DSA:3.40.50.1000 80 179 1.1E-29 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 6 169 4.2E-12 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS07275 28072d45f374d8dc4fa10f20e916f847 186 SUPERFAMILY SSF56784 1 181 5.93E-36 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07800 6625bacd4178150e0b24e5abc4f4da52 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 56 1.3E-16 T 21-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HSISS4_RS07800 6625bacd4178150e0b24e5abc4f4da52 84 PANTHER PTHR33713 1 82 2.4E-21 T 21-04-2016 HSISS4_RS07800 6625bacd4178150e0b24e5abc4f4da52 84 PANTHER PTHR33713:SF6 1 82 2.4E-21 T 21-04-2016 HSISS4_RS07800 6625bacd4178150e0b24e5abc4f4da52 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 75 3.0E-14 T 21-04-2016 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM HSISS4_RS07800 6625bacd4178150e0b24e5abc4f4da52 84 SUPERFAMILY SSF143120 1 80 2.79E-16 T 21-04-2016 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 SUPERFAMILY SSF55681 6 284 8.45E-129 T 21-04-2016 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 Gene3D G3DSA:3.30.930.10 2 207 1.8E-100 T 21-04-2016 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PANTHER PTHR30075 1 305 4.8E-247 T 21-04-2016 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 59 74 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 80 100 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 245 261 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 160 175 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 137 157 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 111 135 1.7E-64 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 7 283 2.2E-144 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 Gene3D G3DSA:1.20.58.180 209 290 1.6E-37 T 21-04-2016 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 5 285 57.627 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS02375 d92c626484f910ebc976ab4e123ed345 305 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 6 291 5.0E-154 T 21-04-2016 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 HSISS4_RS05965 a52e694d217ebde580dc26ee5b7aaedb 170 PANTHER PTHR23091:SF187 1 170 4.9E-26 T 21-04-2016 HSISS4_RS05965 a52e694d217ebde580dc26ee5b7aaedb 170 PANTHER PTHR23091 1 170 4.9E-26 T 21-04-2016 HSISS4_RS05965 a52e694d217ebde580dc26ee5b7aaedb 170 SUPERFAMILY SSF55729 1 162 1.4E-36 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05965 a52e694d217ebde580dc26ee5b7aaedb 170 Pfam PF13420 Acetyltransferase (GNAT) domain 4 157 3.1E-40 T 21-04-2016 HSISS4_RS05965 a52e694d217ebde580dc26ee5b7aaedb 170 Gene3D G3DSA:3.40.630.30 2 163 1.2E-47 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 PANTHER PTHR30177:SF4 1 202 4.0E-216 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 PANTHER PTHR30177:SF4 267 504 4.0E-216 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Gene3D G3DSA:3.40.190.10 454 505 5.8E-61 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Gene3D G3DSA:3.40.190.10 232 344 5.8E-61 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 PANTHER PTHR30177 1 202 4.0E-216 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 PANTHER PTHR30177 267 504 4.0E-216 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 SUPERFAMILY SSF161098 14 198 1.96E-35 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 SUPERFAMILY SSF53850 236 504 2.17E-72 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Gene3D G3DSA:3.40.190.120 345 442 6.9E-40 T 21-04-2016 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 203 2.5E-21 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Gene3D G3DSA:1.10.3720.10 5 198 4.2E-36 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05270 e3c3d16bd2047fadf3a18d5d2a8f25b3 506 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 236 498 4.6E-65 T 21-04-2016 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 PANTHER PTHR30309:SF0 1 213 2.3E-74 T 21-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 PANTHER PTHR30309 1 213 2.3E-74 T 21-04-2016 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 Pfam PF02660 Glycerol-3-phosphate acyltransferase 9 192 7.5E-50 T 21-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 3 199 2.2E-49 T 21-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 SMART SM01207 8 193 3.1E-75 T 21-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 HSISS4_RS02755 6ef24e29a00def3f4096e920e6573693 213 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 5 201 18.921 T 21-04-2016 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 UniPathway: UPA00085 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF81653 112 218 2.09E-22 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Gene3D G3DSA:3.40.1110.10 326 505 5.1E-23 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Pfam PF00122 E1-E2 ATPase 79 327 4.8E-44 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 587 691 1.1E-23 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 615 631 8.7E-11 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 646 671 8.7E-11 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 483 501 8.7E-11 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Pfam PF00689 Cation transporting ATPase, C-terminus 699 874 3.2E-36 T 21-04-2016 IPR006068 Cation-transporting P-type ATPase, C-terminal HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF81660 342 523 2.62E-20 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PANTHER PTHR24093 768 871 8.8E-201 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PANTHER PTHR24093 5 750 8.8E-201 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Gene3D G3DSA:1.20.1110.10 584 876 8.5E-74 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Gene3D G3DSA:1.20.1110.10 40 104 8.5E-74 T 21-04-2016 IPR023298 P-type ATPase, transmembrane domain HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 TIGRFAM TIGR01517 ATPase-IIB_Ca: calcium-translocating P-type ATPase, PMCA-type 3 866 4.0E-161 T 21-04-2016 IPR006408 P-type ATPase, subfamily IIB GO:0005388|GO:0005524|GO:0016020|GO:0070588 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 629 1.0E-17 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Gene3D G3DSA:2.70.150.10 105 221 7.4E-34 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Gene3D G3DSA:2.70.150.10 5 39 7.4E-34 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 Pfam PF00690 Cation transporter/ATPase, N-terminus 5 52 1.3E-8 T 21-04-2016 IPR004014 Cation-transporting P-type ATPase, N-terminal HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF81665 5 110 4.18E-84 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF81665 664 875 4.18E-84 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF81665 221 330 4.18E-84 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 650 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 634 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 512 523 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 544 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 157 171 1.6E-29 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF56784 480 719 2.06E-41 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 SUPERFAMILY SSF56784 335 354 2.06E-41 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 338 344 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PANTHER PTHR24093:SF254 768 871 8.8E-201 T 21-04-2016 HSISS4_RS05720 6380377b778bf5f6688c838cd4e56658 878 PANTHER PTHR24093:SF254 5 750 8.8E-201 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 SUPERFAMILY SSF52540 565 781 2.61E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799 224 231 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799 251 299 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799 8 82 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799 572 1030 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 SMART SM00487 581 762 1.9E-34 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Pfam PF00176 SNF2 family N-terminal domain 600 852 1.8E-43 T 21-04-2016 IPR000330 SNF2-related, N-terminal domain GO:0005524 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 SMART SM00490 891 973 3.8E-23 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Pfam PF00271 Helicase conserved C-terminal domain 862 973 4.7E-21 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 SUPERFAMILY SSF52540 783 1027 6.55E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Gene3D G3DSA:3.40.50.300 857 1008 3.9E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Gene3D G3DSA:3.40.50.300 581 748 1.2E-29 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Pfam PF04434 SWIM zinc finger 48 73 7.5E-4 T 21-04-2016 IPR007527 Zinc finger, SWIM-type GO:0008270 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799:SF651 224 231 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799:SF651 251 299 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799:SF651 8 82 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 PANTHER PTHR10799:SF651 572 1030 8.8E-231 T 21-04-2016 HSISS4_RS01145 8b5e849b32f806efe89506cc8677c622 1031 Pfam PF08455 Bacterial SNF2 helicase associated 215 575 3.2E-53 T 21-04-2016 IPR013663 Helicase, SWF/SNF/SWI type, bacterial HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 PANTHER PTHR10954 2 254 1.0E-102 T 21-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 Gene3D G3DSA:3.30.420.10 71 210 1.9E-44 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 SUPERFAMILY SSF53098 60 254 3.79E-65 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 PANTHER PTHR10954:SF7 2 254 1.0E-102 T 21-04-2016 HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 Hamap MF_00052_B Ribonuclease HII [rnhB]. 71 249 35.062 T 21-04-2016 IPR022898 Ribonuclease HII GO:0004523 HSISS4_RS05395 4a17b190857ef12ba9a1427641fa8c5f 256 Pfam PF01351 Ribonuclease HII 73 247 2.1E-35 T 21-04-2016 IPR024567 Ribonuclease HII/HIII domain HSISS4_RS06210 0e3f2e5d5292ab4238b3053293229759 210 PANTHER PTHR34582:SF6 4 210 9.2E-67 T 21-04-2016 HSISS4_RS06210 0e3f2e5d5292ab4238b3053293229759 210 Gene3D G3DSA:3.30.240.20 83 155 9.4E-23 T 21-04-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HSISS4_RS06210 0e3f2e5d5292ab4238b3053293229759 210 Gene3D G3DSA:3.30.240.20 156 210 7.7E-18 T 21-04-2016 IPR023090 Uncharacterised domain UPF0702, alpha/beta domain HSISS4_RS06210 0e3f2e5d5292ab4238b3053293229759 210 Pfam PF04239 Protein of unknown function (DUF421) 90 190 6.4E-31 T 21-04-2016 IPR007353 Protein of unknown function DUF421 HSISS4_RS06210 0e3f2e5d5292ab4238b3053293229759 210 PANTHER PTHR34582 4 210 9.2E-67 T 21-04-2016 HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 Pfam PF13662 Toprim domain 8 73 1.0E-5 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 SMART SM00493 7 80 6.1E-4 T 21-04-2016 IPR006171 Toprim domain HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 Gene3D G3DSA:3.40.1360.20 4 124 3.0E-39 T 21-04-2016 HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 5 182 3.5E-46 T 21-04-2016 IPR004466 Ribonuclease M5 GO:0043822 HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 PANTHER PTHR39156 3 186 1.7E-77 T 21-04-2016 HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 Pfam PF13331 Domain of unknown function (DUF4093) 98 183 1.3E-30 T 21-04-2016 IPR025156 Ribonuclease M5, C-terminal domain HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 SUPERFAMILY SSF110455 4 123 3.27E-35 T 21-04-2016 HSISS4_RS08640 13fa5f95cb0927ed4f0b311c90b65b2d 186 Hamap MF_01469 Ribonuclease M5 [rnmV]. 6 186 30.956 T 21-04-2016 IPR004466 Ribonuclease M5 GO:0043822 HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 Pfam PF00881 Nitroreductase family 11 163 2.9E-18 T 21-04-2016 IPR029479 Nitroreductase HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 SUPERFAMILY SSF55469 1 247 2.36E-61 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 PANTHER PTHR23026:SF98 1 189 3.6E-58 T 21-04-2016 HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 Gene3D G3DSA:3.40.109.10 1 246 7.0E-64 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 PIRSF PIRSF005426 1 248 4.1E-86 T 21-04-2016 IPR016446 Flavin oxidoreductase Frp family GO:0016491|GO:0055114 HSISS4_RS04425 faaf489314e2b288747d7fca16fa39c1 248 PANTHER PTHR23026 1 189 3.6E-58 T 21-04-2016 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 PANTHER PTHR30055:SF55 1 171 5.6E-26 T 21-04-2016 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 PANTHER PTHR30055 1 171 5.6E-26 T 21-04-2016 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 Gene3D G3DSA:1.10.357.10 1 172 1.3E-17 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 SUPERFAMILY SSF46689 3 65 2.74E-13 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 Pfam PF14278 Transcriptional regulator C-terminal region 80 155 3.0E-7 T 21-04-2016 HSISS4_RS05240 1c6574f90a0fc582b86ed5ccfc6c7363 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 57 4.3E-6 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 121 249 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 280 407 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 484 596 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 726 777 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 640 709 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795 426 446 5.0E-71 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2131 2161 0.0011 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 692 702 - T 21-04-2016 IPR023828 Peptidase S8, subtilisin, Ser-active site HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Pfam PF00082 Subtilase family 227 768 1.9E-42 T 21-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Pfam PF06280 Fn3-like domain 799 938 1.3E-29 T 21-04-2016 IPR010435 Fn3-like domain GO:0004252|GO:0005618|GO:0016020 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Pfam PF02225 PA domain 500 579 4.1E-5 T 21-04-2016 IPR003137 PA domain HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 121 249 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 280 407 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 484 596 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 726 777 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 640 709 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PANTHER PTHR10795:SF419 426 446 5.0E-71 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 SUPERFAMILY SSF52743 222 460 3.67E-49 T 21-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 SUPERFAMILY SSF52743 647 776 3.67E-49 T 21-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Gene3D G3DSA:3.40.50.200 209 457 1.6E-86 T 21-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Gene3D G3DSA:3.40.50.200 651 777 1.6E-86 T 21-04-2016 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Gene3D G3DSA:3.50.30.30 484 593 1.8E-7 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 Gene3D G3DSA:3.30.70.80 131 197 1.1E-4 T 21-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 SUPERFAMILY SSF52025 486 548 4.58E-5 T 21-04-2016 HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PRINTS PR00723 Subtilisin serine protease family (S8) signature 227 246 2.1E-6 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 PRINTS PR00723 Subtilisin serine protease family (S8) signature 691 707 2.1E-6 T 21-04-2016 IPR015500 Peptidase S8, subtilisin-related HSISS4_RS06045 9786973a55397395ac4c33c107303425 2164 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 303 313 - T 21-04-2016 IPR022398 Peptidase S8, subtilisin, His-active site HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 SUPERFAMILY SSF69360 136 274 2.35E-15 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 473 546 2.5E-13 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 152 216 3.1E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 288 347 2.0E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 349 406 7.6E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 409 471 2.0E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 766 825 8.5E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 550 612 3.3E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 SUPERFAMILY SSF69360 743 838 6.41E-22 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 780 838 1.4E-10 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 224 330 8.7E-14 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 534 591 2.3E-9 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 421 481 1.5E-11 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 482 497 2.3E-9 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Pfam PF01473 Putative cell wall binding repeat 757 774 0.013 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Pfam PF01473 Putative cell wall binding repeat 279 296 2.5E-5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Pfam PF01473 Putative cell wall binding repeat 668 684 0.22 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Pfam PF01473 Putative cell wall binding repeat 464 481 0.046 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 655 775 4.0E-19 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 331 420 5.4E-16 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 148 193 4.6E-9 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 Gene3D G3DSA:2.10.270.10 592 641 1.9E-6 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 SUPERFAMILY SSF69360 655 702 9.81E-8 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 SUPERFAMILY SSF69360 462 665 1.67E-21 T 21-04-2016 HSISS4_RS06605 4fd0ab3e0abd248e14e77717394118b5 841 SUPERFAMILY SSF69360 278 459 4.94E-32 T 21-04-2016 HSISS4_RS06020 f6e3eeeda3cf6018cb378418aa54a9e2 306 Pfam PF12844 Helix-turn-helix domain 10 70 3.1E-8 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06020 f6e3eeeda3cf6018cb378418aa54a9e2 306 SMART SM00530 12 68 0.0058 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06020 f6e3eeeda3cf6018cb378418aa54a9e2 306 SUPERFAMILY SSF47413 4 73 2.04E-11 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06020 f6e3eeeda3cf6018cb378418aa54a9e2 306 Gene3D G3DSA:1.10.260.40 2 78 3.4E-13 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 11 30 - T 21-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 5 359 1.5E-146 T 21-04-2016 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 189 199 - T 21-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 2 373 47.852 T 21-04-2016 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 SUPERFAMILY SSF53448 2 262 8.45E-85 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 SUPERFAMILY SSF53448 323 339 8.45E-85 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 326 359 0.0011 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 PANTHER PTHR22572:SF10 6 364 1.9E-168 T 21-04-2016 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 21-04-2016 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|UniPathway: UPA00164 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 SUPERFAMILY SSF51161 279 373 5.54E-15 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 Pfam PF00483 Nucleotidyl transferase 7 258 1.1E-65 T 21-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 3 367 7.8E-71 T 21-04-2016 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 PANTHER PTHR22572 6 364 1.9E-168 T 21-04-2016 HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 Gene3D G3DSA:3.90.550.10 306 349 2.5E-87 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06850 a062dbe0c04fb4cfdd3c31623a1c5683 380 Gene3D G3DSA:3.90.550.10 4 269 2.5E-87 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 Gene3D G3DSA:3.40.140.10 5 152 3.2E-60 T 21-04-2016 HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 PANTHER PTHR11079 10 157 1.9E-51 T 21-04-2016 HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 95 - T 21-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 SUPERFAMILY SSF53927 7 158 5.52E-53 T 21-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 13 154 45.537 T 21-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 HSISS4_RS08965 ade430ecfd2bab9e30f2c668ea73dbdb 172 Pfam PF14437 MafB19-like deaminase 9 154 1.9E-37 T 21-04-2016 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 26.227 T 21-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 PANTHER PTHR21043 4 111 5.9E-42 T 21-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 Gene3D G3DSA:3.30.460.10 3 107 5.1E-40 T 21-04-2016 HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 7.0E-28 T 21-04-2016 HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 SUPERFAMILY SSF81301 3 114 1.32E-40 T 21-04-2016 HSISS4_RS07815 4c48ced0acadef1236995dfa7b5ddbbd 117 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 3.5E-37 T 21-04-2016 IPR004394 Protein Iojap/ribosomal silencing factor RsfS HSISS4_RS04630 2ea0e3668db4f78bb01a3f5c806b766a 356 PANTHER PTHR22916:SF24 1 336 1.0E-42 T 21-04-2016 HSISS4_RS04630 2ea0e3668db4f78bb01a3f5c806b766a 356 Gene3D G3DSA:3.90.550.10 2 207 4.7E-46 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS04630 2ea0e3668db4f78bb01a3f5c806b766a 356 SUPERFAMILY SSF53448 6 231 1.03E-46 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS04630 2ea0e3668db4f78bb01a3f5c806b766a 356 PANTHER PTHR22916 1 336 1.0E-42 T 21-04-2016 HSISS4_RS04630 2ea0e3668db4f78bb01a3f5c806b766a 356 Pfam PF00535 Glycosyl transferase family 2 7 136 2.4E-29 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 Gene3D G3DSA:1.10.600.10 6 263 1.2E-79 T 21-04-2016 IPR008949 Isoprenoid synthase domain HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 206 218 - T 21-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 92 - T 21-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 Pfam PF00348 Polyprenyl synthetase 27 260 1.3E-51 T 21-04-2016 IPR000092 Polyprenyl synthetase GO:0008299 HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 PANTHER PTHR12001 1 262 3.9E-87 T 21-04-2016 IPR017446 Polyprenyl synthetase-related HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 SUPERFAMILY SSF48576 4 266 1.97E-75 T 21-04-2016 IPR008949 Isoprenoid synthase domain HSISS4_RS04065 c5e98732f71bee6eb1e01e82d38ea54d 290 PANTHER PTHR12001:SF23 1 262 3.9E-87 T 21-04-2016 HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 PANTHER PTHR10681:SF81 3 164 1.4E-48 T 21-04-2016 HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 Gene3D G3DSA:3.40.30.10 4 164 1.7E-45 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 PANTHER PTHR10681 3 164 1.4E-48 T 21-04-2016 HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 ProSitePatterns PS01265 Tpx family signature. 82 93 - T 21-04-2016 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 Pfam PF08534 Redoxin 18 157 1.3E-25 T 21-04-2016 IPR013740 Redoxin GO:0016491 HSISS4_RS04945 0f149866a9182482cfe47ae689fc717c 164 SUPERFAMILY SSF52833 5 159 4.02E-40 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 SUPERFAMILY SSF53062 4 121 5.49E-29 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 5 119 3.5E-33 T 21-04-2016 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 Gene3D G3DSA:3.40.50.510 3 121 8.0E-36 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 PANTHER PTHR38594 2 120 1.1E-29 T 21-04-2016 HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 Pfam PF03610 PTS system fructose IIA component 5 109 2.9E-20 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS06455 bef099066ab6dfc650fbd31d8ec4e5f1 124 PANTHER PTHR38594:SF1 2 120 1.1E-29 T 21-04-2016 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 226 369 2.1E-27 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 15 456 1.2E-130 T 21-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:1.20.120.430 386 456 2.9E-55 T 21-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:1.20.120.430 253 277 2.9E-55 T 21-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:1.20.120.430 127 187 2.9E-55 T 21-04-2016 IPR027368 tRNA modification GTPase MnmE domain 2 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:3.40.50.300 292 385 2.1E-14 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 PANTHER PTHR11649:SF56 11 456 7.1E-162 T 21-04-2016 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 PANTHER PTHR11649 11 456 7.1E-162 T 21-04-2016 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 SUPERFAMILY SSF116878 381 456 1.14E-48 T 21-04-2016 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 SUPERFAMILY SSF116878 127 226 1.14E-48 T 21-04-2016 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Pfam PF01926 50S ribosome-binding GTPase 226 337 3.2E-26 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:3.40.50.300 223 252 7.5E-5 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Gene3D G3DSA:3.30.1360.120 3 126 7.4E-48 T 21-04-2016 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Pfam PF10396 GTP-binding protein TrmE N-terminus 9 125 8.7E-41 T 21-04-2016 IPR018948 GTP-binding protein TrmE, N-terminal HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Pfam PF12631 MnmE helical domain 128 453 1.1E-57 T 21-04-2016 IPR025867 MnmE, helical domain HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 SUPERFAMILY SSF52540 203 371 5.84E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 SUPERFAMILY SSF52540 80 168 5.84E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04970 79c5d2d145a20afb73c34b2bfcf0ffc5 456 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 8 456 34.006 T 21-04-2016 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 6 365 55.788 T 21-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 PANTHER PTHR21148 1 371 4.5E-171 T 21-04-2016 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 8 374 1.6E-170 T 21-04-2016 IPR004803 Queuine tRNA-ribosyltransferase GO:0008033|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 Pfam PF01702 Queuine tRNA-ribosyltransferase 134 367 2.7E-87 T 21-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 Gene3D G3DSA:3.20.20.105 6 372 1.1E-159 T 21-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 SUPERFAMILY SSF51713 7 371 6.8E-152 T 21-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 PANTHER PTHR21148:SF26 1 371 4.5E-171 T 21-04-2016 HSISS4_RS08765 e96e55dc271ea85ee24f8b312c572411 380 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 8 374 1.2E-161 T 21-04-2016 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0008479|GO:0008616 MetaCyc: PWY-6700|UniPathway: UPA00392 HSISS4_RS07725 194b2b366c589ddbf8e722f6a8cd4073 196 SMART SM00479 6 171 1.0E-18 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS07725 194b2b366c589ddbf8e722f6a8cd4073 196 PANTHER PTHR30231 5 172 5.6E-18 T 21-04-2016 HSISS4_RS07725 194b2b366c589ddbf8e722f6a8cd4073 196 SUPERFAMILY SSF53098 6 171 1.0E-29 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS07725 194b2b366c589ddbf8e722f6a8cd4073 196 Gene3D G3DSA:3.30.420.10 5 169 2.3E-29 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS07725 194b2b366c589ddbf8e722f6a8cd4073 196 Pfam PF00929 Exonuclease 8 162 1.6E-14 T 21-04-2016 IPR013520 Exonuclease, RNase T/DNA polymerase III HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 Pfam PF00654 Voltage gated chloride channel 74 408 2.2E-44 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 PRINTS PR00762 Chloride channel signature 114 133 2.8E-6 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 PRINTS PR00762 Chloride channel signature 165 184 2.8E-6 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 PRINTS PR00762 Chloride channel signature 358 374 2.8E-6 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 SUPERFAMILY SSF81340 17 411 2.09E-56 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS04570 6e1db48bb66f08b4aa8f4ddadc5282c4 415 Gene3D G3DSA:1.10.3080.10 14 412 1.3E-42 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS07265 b7a08b71b54a0654f35828c28e01e560 574 Pfam PF06160 Septation ring formation regulator, EzrA 8 565 6.5E-184 T 21-04-2016 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 HSISS4_RS07265 b7a08b71b54a0654f35828c28e01e560 574 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 6 568 26.429 T 21-04-2016 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 HSISS4_RS07265 b7a08b71b54a0654f35828c28e01e560 574 PANTHER PTHR41314 3 574 3.4E-149 T 21-04-2016 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 Gene3D G3DSA:1.10.10.10 9 65 4.1E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 Hamap MF_00173 Arginine repressor [argR]. 1 141 53.785 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 SUPERFAMILY SSF55252 75 140 2.62E-18 T 21-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 TIGRFAM TIGR01529 argR_whole: arginine repressor 4 140 3.1E-50 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 Pfam PF01316 Arginine repressor, DNA binding domain 2 65 1.9E-24 T 21-04-2016 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PRINTS PR01467 Bacterial arginine repressor signature 20 33 1.2E-17 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PRINTS PR01467 Bacterial arginine repressor signature 113 128 1.2E-17 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PRINTS PR01467 Bacterial arginine repressor signature 36 51 1.2E-17 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PRINTS PR01467 Bacterial arginine repressor signature 83 96 1.2E-17 T 21-04-2016 IPR001669 Arginine repressor GO:0003700|GO:0006355 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PANTHER PTHR34471 1 140 2.9E-46 T 21-04-2016 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 Pfam PF02863 Arginine repressor, C-terminal domain 76 140 1.3E-19 T 21-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 SUPERFAMILY SSF46785 2 66 8.91E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 Gene3D G3DSA:3.30.1360.40 71 140 1.0E-23 T 21-04-2016 IPR024946 Arginine repressor C-terminal-like domain HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 85 140 3.0E-5 T 21-04-2016 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 UniPathway: UPA00068 HSISS4_RS00290 11490e125f7fde6143fe07779a730c33 141 PANTHER PTHR34471:SF1 1 140 2.9E-46 T 21-04-2016 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 PANTHER PTHR11136:SF0 1 412 1.1E-123 T 21-04-2016 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 141 156 - T 21-04-2016 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 PANTHER PTHR11136 1 412 1.1E-123 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 TIGRFAM TIGR01499 folC: bifunctional protein FolC 22 412 1.3E-118 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 Gene3D G3DSA:3.40.1190.10 1 293 3.2E-89 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 SUPERFAMILY SSF53623 1 292 2.75E-85 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 PIRSF PIRSF001563 1 417 1.4E-122 T 21-04-2016 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|UniPathway: UPA00850 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 Gene3D G3DSA:3.90.190.20 294 414 6.4E-21 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 Pfam PF08245 Mur ligase middle domain 45 267 3.7E-11 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01875 9b70ee7e5335c6da47d4e09adb0fc3bf 418 SUPERFAMILY SSF53244 294 412 2.75E-20 T 21-04-2016 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 UniPathway: UPA00219 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 PANTHER PTHR11644 1 129 1.4E-61 T 21-04-2016 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 99 2.7E-18 T 21-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 96 - T 21-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 SUPERFAMILY SSF53927 7 129 2.68E-47 T 21-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 Gene3D G3DSA:3.40.140.10 2 129 1.8E-54 T 21-04-2016 HSISS4_RS05635 5a0731469aa02a4ca606abc076a3fbd6 132 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 8 129 1.6E-48 T 21-04-2016 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 HSISS4_RS04710 d20e3ff9435a8f2e53302c7e1b287f2a 283 SUPERFAMILY SSF52151 1 276 1.62E-48 T 21-04-2016 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 HSISS4_RS04710 d20e3ff9435a8f2e53302c7e1b287f2a 283 Gene3D G3DSA:3.40.1090.10 5 166 1.3E-5 T 21-04-2016 HSISS4_RS04710 d20e3ff9435a8f2e53302c7e1b287f2a 283 PANTHER PTHR14226 2 280 4.3E-65 T 21-04-2016 HSISS4_RS04710 d20e3ff9435a8f2e53302c7e1b287f2a 283 Pfam PF01734 Patatin-like phospholipase 5 169 2.5E-19 T 21-04-2016 IPR002641 Patatin/Phospholipase A2-related GO:0006629 HSISS4_RS04710 d20e3ff9435a8f2e53302c7e1b287f2a 283 PANTHER PTHR14226:SF25 2 280 4.3E-65 T 21-04-2016 HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 Gene3D G3DSA:3.30.1240.10 82 175 2.7E-21 T 21-04-2016 HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 Gene3D G3DSA:3.40.50.1000 2 72 5.3E-37 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 Gene3D G3DSA:3.40.50.1000 176 260 5.3E-37 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 Pfam PF08282 haloacid dehalogenase-like hydrolase 4 255 1.0E-49 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 PANTHER PTHR10000 2 262 1.1E-59 T 21-04-2016 HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 3 228 1.4E-21 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 PANTHER PTHR10000:SF27 2 262 1.1E-59 T 21-04-2016 HSISS4_RS06960 f25e6d18b96639333c488bf1c733815a 264 SUPERFAMILY SSF56784 2 259 3.56E-55 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 Gene3D G3DSA:3.10.180.40 67 193 6.8E-45 T 21-04-2016 HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 Pfam PF14506 CppA N-terminal 9 133 1.9E-61 T 21-04-2016 IPR032702 CppA, N-terminal HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 Pfam PF14507 CppA C-terminal 147 249 2.0E-36 T 21-04-2016 IPR032703 CppA, C-terminal HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 Gene3D G3DSA:3.10.180.10 1 66 3.0E-38 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 Gene3D G3DSA:3.10.180.10 194 251 3.0E-38 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS08055 a5f81a44545ab82ee3055b08a9cdefd0 251 SUPERFAMILY SSF54593 8 231 7.68E-9 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 Pfam PF00344 SecY translocase 64 382 1.5E-41 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 SUPERFAMILY SSF103491 7 393 8.76E-62 T 21-04-2016 IPR023201 SecY subunit domain HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 Hamap MF_01466 Accessory Sec system protein translocase subunit SecY2 [secY2]. 1 405 27.737 T 21-04-2016 IPR014269 Accessory Sec system protein translocase subunit SecY2 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PANTHER PTHR10906 9 362 2.4E-23 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PIRSF PIRSF004557 1 408 9.1E-70 T 21-04-2016 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: REACT_15380 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 13 31 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 63 83 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 340 358 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 131 156 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 241 260 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PRINTS PR00303 Preprotein translocase SecY subunit signature 285 307 1.7E-24 T 21-04-2016 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 TIGRFAM TIGR02920 acc_sec_Y2: accessory Sec system translocase SecY2 8 405 2.4E-120 T 21-04-2016 IPR014269 Accessory Sec system protein translocase subunit SecY2 HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 Gene3D G3DSA:1.10.3370.10 8 405 1.7E-70 T 21-04-2016 IPR023201 SecY subunit domain HSISS4_RS06760 e1472490552ef6ef2018578702b56e68 408 PANTHER PTHR10906:SF2 9 362 2.4E-23 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 Gene3D G3DSA:1.10.260.40 1 48 1.2E-19 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 SUPERFAMILY SSF53822 74 309 1.96E-44 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 Gene3D G3DSA:3.40.50.2300 164 331 2.2E-47 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 PANTHER PTHR30146 1 330 2.0E-133 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 8.4E-6 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 8.4E-6 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 SUPERFAMILY SSF47413 1 58 1.13E-12 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 SMART SM00354 1 72 1.6E-11 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 PANTHER PTHR30146:SF28 1 330 2.0E-133 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 Gene3D G3DSA:3.40.50.2300 109 163 4.7E-6 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.7E-16 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 Pfam PF13377 Periplasmic binding protein-like domain 165 330 1.3E-29 T 21-04-2016 HSISS4_RS06390 3e7909ee28c618f458b7327e72ef80f0 331 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 Pfam PF00106 short chain dehydrogenase 3 195 9.6E-54 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 Gene3D G3DSA:3.40.50.720 3 238 4.1E-64 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.8E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.8E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.8E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.8E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.8E-25 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PANTHER PTHR24319:SF32 5 255 2.6E-59 T 21-04-2016 HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.6E-9 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.6E-9 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.6E-9 T 21-04-2016 IPR002347 Short-chain dehydrogenase/reductase SDR HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 PANTHER PTHR24319 5 255 2.6E-59 T 21-04-2016 HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 SUPERFAMILY SSF51735 2 230 2.83E-61 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03470 203310bd8479acc6fd78519594a9241f 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 21-04-2016 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 585 785 1.2E-63 T 21-04-2016 IPR017501 Phage infection protein, YhgE, C-terminal HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 PANTHER PTHR30294:SF25 4 244 6.5E-77 T 21-04-2016 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 PANTHER PTHR30294:SF25 601 789 6.5E-77 T 21-04-2016 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 519 546 3.8E-5 T 21-04-2016 IPR023908 xxxLxxG heptad repeat HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 212 236 1.4E-4 T 21-04-2016 IPR023908 xxxLxxG heptad repeat HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 197 224 4.0E-5 T 21-04-2016 IPR023908 xxxLxxG heptad repeat HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 Pfam PF12698 ABC-2 family transporter protein 15 149 1.5E-10 T 21-04-2016 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 PANTHER PTHR30294 4 244 6.5E-77 T 21-04-2016 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 PANTHER PTHR30294 601 789 6.5E-77 T 21-04-2016 HSISS4_RS09570 100c22c9429e6f46869abe5eb5e57f1d 789 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 4 166 1.3E-60 T 21-04-2016 IPR017500 Phage infection protein, YhgE, N-terminal HSISS4_RS09445 84e16fa5f74d8a82e1847dd4f703ef58 243 Pfam PF03883 Protein of unknown function (DUF328) 4 230 9.7E-51 T 21-04-2016 IPR005583 Peroxide stress protein YaaA HSISS4_RS09445 84e16fa5f74d8a82e1847dd4f703ef58 243 PANTHER PTHR30283 3 241 7.4E-50 T 21-04-2016 HSISS4_RS09445 84e16fa5f74d8a82e1847dd4f703ef58 243 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 2 242 27.505 T 21-04-2016 IPR005583 Peroxide stress protein YaaA HSISS4_RS09445 84e16fa5f74d8a82e1847dd4f703ef58 243 PANTHER PTHR30283:SF3 3 241 7.4E-50 T 21-04-2016 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 Gene3D G3DSA:3.30.360.10 161 316 2.0E-71 T 21-04-2016 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PIRSF PIRSF000149 1 336 1.7E-113 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 152 1.9E-51 T 21-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 SUPERFAMILY SSF51735 3 168 1.1E-56 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 2.8E-131 T 21-04-2016 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PANTHER PTHR10836 1 334 5.0E-239 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PANTHER PTHR10836:SF57 1 334 5.0E-239 T 21-04-2016 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 314 2.0E-64 T 21-04-2016 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 4.2E-31 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 267 282 4.2E-31 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 4.2E-31 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 4.2E-31 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 4.2E-31 T 21-04-2016 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 SUPERFAMILY SSF55347 151 314 1.07E-67 T 21-04-2016 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 Gene3D G3DSA:3.40.50.720 1 160 3.6E-67 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 21-04-2016 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS08580 7085c7183c0935893ae6c9eccb706891 336 SMART SM00846 3 152 2.1E-80 T 21-04-2016 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: REACT_474 HSISS4_RS07085 269738c4a0244092cffa232b3e24316e 318 SUPERFAMILY SSF53448 2 230 2.91E-47 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07085 269738c4a0244092cffa232b3e24316e 318 PANTHER PTHR22916 1 242 2.4E-33 T 21-04-2016 HSISS4_RS07085 269738c4a0244092cffa232b3e24316e 318 Pfam PF00535 Glycosyl transferase family 2 5 111 8.2E-21 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS07085 269738c4a0244092cffa232b3e24316e 318 Gene3D G3DSA:3.90.550.10 1 247 7.5E-44 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 Gene3D G3DSA:3.40.50.300 255 496 2.8E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 Gene3D G3DSA:3.40.50.300 3 232 1.2E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 Pfam PF00005 ABC transporter 276 432 2.2E-18 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 Pfam PF00005 ABC transporter 23 172 6.1E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 PANTHER PTHR24220:SF239 8 385 3.3E-192 T 21-04-2016 HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 SUPERFAMILY SSF52540 6 228 2.07E-60 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 PANTHER PTHR24220 8 385 3.3E-192 T 21-04-2016 HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 ProSitePatterns PS00211 ABC transporters family signature. 405 419 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 SMART SM00382 31 220 5.8E-17 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 SMART SM00382 285 481 19.0 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05625 4cc0821ac3b7cbcb9adec64d708c5b3d 512 SUPERFAMILY SSF52540 258 491 9.55E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 Gene3D G3DSA:3.20.20.30 2 345 2.7E-79 T 21-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 SUPERFAMILY SSF51679 22 343 1.2E-68 T 21-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 PANTHER PTHR30137 2 348 5.3E-134 T 21-04-2016 HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 PANTHER PTHR30137:SF8 2 348 5.3E-134 T 21-04-2016 HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 Pfam PF00296 Luciferase-like monooxygenase 21 305 2.6E-37 T 21-04-2016 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 HSISS4_RS07435 efec17e9e62f1f42f27c9dec6dab272d 349 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 4 342 1.4E-152 T 21-04-2016 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 Pfam PF01263 Aldose 1-epimerase 18 341 1.3E-77 T 21-04-2016 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 ProSitePatterns PS00545 Aldose 1-epimerase putative active site. 176 185 - T 21-04-2016 IPR018052 Aldose 1-epimerase, conserved site KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 Gene3D G3DSA:2.70.98.10 10 342 1.2E-86 T 21-04-2016 IPR014718 Glycoside hydrolase-type carbohydrate-binding, subgroup GO:0003824|GO:0005975|GO:0030246 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 PANTHER PTHR10091:SF0 12 342 4.6E-80 T 21-04-2016 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 SUPERFAMILY SSF74650 2 342 3.58E-88 T 21-04-2016 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 PANTHER PTHR10091 12 342 4.6E-80 T 21-04-2016 HSISS4_RS06370 733c02ccf935b39394f27c7e316dd714 348 PIRSF PIRSF005096 1 346 5.2E-85 T 21-04-2016 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317|UniPathway: UPA00242 HSISS4_RS02695 346124eecbf2c1e75a9b913d34a9f41f 225 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 23 221 4.5E-58 T 21-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 HSISS4_RS02695 346124eecbf2c1e75a9b913d34a9f41f 225 PANTHER PTHR20855:SF3 23 225 1.4E-51 T 21-04-2016 IPR005744 Hly-III GO:0016021|GO:0019835 HSISS4_RS02695 346124eecbf2c1e75a9b913d34a9f41f 225 PANTHER PTHR20855 23 225 1.4E-51 T 21-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HSISS4_RS02695 346124eecbf2c1e75a9b913d34a9f41f 225 Pfam PF03006 Haemolysin-III related 22 216 8.5E-30 T 21-04-2016 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 Pfam PF00694 Aconitase C-terminal domain 1 122 6.6E-39 T 21-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 PANTHER PTHR11670:SF27 1 196 5.2E-98 T 21-04-2016 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 PANTHER PTHR11670 1 196 5.2E-98 T 21-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 195 41.011 T 21-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 184 3.7E-67 T 21-04-2016 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 SUPERFAMILY SSF52016 1 193 2.16E-57 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS04140 539a685af4bdfaf35a78880d70e74888 196 Gene3D G3DSA:3.20.19.10 1 191 3.2E-48 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS01490 f471e0efb26e0503ddb339059f6bf921 128 Pfam PF06115 Domain of unknown function (DUF956) 1 117 3.7E-45 T 21-04-2016 IPR010360 Protein of unknown function DUF956 HSISS4_RS01490 f471e0efb26e0503ddb339059f6bf921 128 PIRSF PIRSF021265 1 123 1.0E-42 T 21-04-2016 IPR010360 Protein of unknown function DUF956 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 70 87 1.8E-11 T 21-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 377 399 1.8E-11 T 21-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 296 314 1.8E-11 T 21-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 155 164 1.8E-11 T 21-04-2016 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 Gene3D G3DSA:2.40.37.10 269 410 1.4E-43 T 21-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PANTHER PTHR11482 11 417 6.0E-127 T 21-04-2016 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 367 380 1.6E-12 T 21-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 269 288 1.6E-12 T 21-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 72 84 1.6E-12 T 21-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 52 70 1.6E-12 T 21-04-2016 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 285 386 7.3E-13 T 21-04-2016 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 SUPERFAMILY SSF50621 258 408 1.11E-44 T 21-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 Gene3D G3DSA:3.20.20.10 29 268 8.8E-58 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 SUPERFAMILY SSF51419 20 281 2.13E-56 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 36 279 1.7E-27 T 21-04-2016 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS01205 bf8b4172cb9271b5c45b220519296194 417 PANTHER PTHR11482:SF5 11 417 6.0E-127 T 21-04-2016 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 SUPERFAMILY SSF52540 74 361 2.63E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 116 248 1.6E-14 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 SMART SM00382 442 594 4.3E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 SMART SM00382 111 258 2.3E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 476 494 - T 21-04-2016 IPR028299 ClpA/B, conserved site 2 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 491 509 6.6E-28 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 446 464 6.6E-28 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 554 568 6.6E-28 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 521 539 6.6E-28 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Gene3D G3DSA:1.10.8.60 259 340 7.2E-25 T 21-04-2016 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 608 678 6.9E-20 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Gene3D G3DSA:3.40.50.300 399 619 7.5E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PANTHER PTHR11638 73 697 0.0 T 21-04-2016 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Pfam PF07724 AAA domain (Cdc48 subfamily) 441 601 9.1E-43 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Gene3D G3DSA:3.40.50.300 74 257 3.0E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 SUPERFAMILY SSF52540 391 679 6.24E-70 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 SMART SM01086 608 695 2.5E-23 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 PANTHER PTHR11638:SF101 73 697 0.0 T 21-04-2016 HSISS4_RS07790 5f18e8c5e86c9db02ef21de01a5a6177 701 Gene3D G3DSA:1.10.8.60 620 696 4.7E-24 T 21-04-2016 HSISS4_RS09080 5c8eeec8713fd635228313ba58177a1e 120 Pfam PF06279 Protein of unknown function (DUF1033) 1 118 1.4E-51 T 21-04-2016 IPR010434 Protein of unknown function DUF1033 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 812 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 742 753 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 764 775 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 705 730 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 680 693 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 604 626 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 650 673 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 627 642 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PRINTS PR00868 DNA-polymerase family A (pol I) signature 826 839 6.9E-81 T 21-04-2016 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:1.10.150.20 194 254 7.6E-31 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SMART SM00482 635 843 2.6E-122 T 21-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 6 178 2.7E-50 T 21-04-2016 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 ProSitePatterns PS00447 DNA polymerase family A signature. 705 724 - T 21-04-2016 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SUPERFAMILY SSF56672 471 879 1.09E-149 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:3.30.70.370 769 879 1.5E-61 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:3.30.70.370 612 661 1.5E-61 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:3.40.50.1010 5 193 1.1E-66 T 21-04-2016 IPR029060 PIN domain-like HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 TIGRFAM TIGR00593 pola: DNA polymerase I 7 879 0.0 T 21-04-2016 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:1.10.150.20 662 768 4.6E-39 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SUPERFAMILY SSF88723 4 178 2.04E-50 T 21-04-2016 IPR029060 PIN domain-like HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PANTHER PTHR10133:SF27 2 879 0.0 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Pfam PF00476 DNA polymerase family A 500 877 2.3E-151 T 21-04-2016 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 179 273 1.3E-32 T 21-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:3.30.420.10 306 491 3.0E-47 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SMART SM00279 181 216 9.4E-16 T 21-04-2016 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SUPERFAMILY SSF47807 179 292 1.94E-34 T 21-04-2016 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SMART SM00474 300 467 1.5E-5 T 21-04-2016 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 PANTHER PTHR10133 2 879 0.0 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SUPERFAMILY SSF53098 307 468 4.4E-31 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 Gene3D G3DSA:1.20.1060.10 493 611 1.2E-35 T 21-04-2016 HSISS4_RS08480 43324aeb4607ebbc190882d11df90f03 879 SMART SM00475 5 270 1.0E-149 T 21-04-2016 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Pfam PF13596 PAS domain 325 434 1.3E-27 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Pfam PF01814 Hemerythrin HHE cation binding domain 88 222 2.0E-21 T 21-04-2016 IPR012312 Haemerythrin-like HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Gene3D G3DSA:3.30.450.20 331 428 3.9E-8 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Gene3D G3DSA:1.20.120.520 82 263 3.6E-69 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Gene3D G3DSA:1.20.120.520 307 330 3.6E-69 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 Pfam PF04282 Family of unknown function (DUF438) 9 76 3.2E-24 T 21-04-2016 IPR007380 Domain of unknown function DUF438 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 PANTHER PTHR24423 1 211 1.6E-54 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 PANTHER PTHR24423 320 447 1.6E-54 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 PANTHER PTHR24423:SF516 1 211 1.6E-54 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 PANTHER PTHR24423:SF516 320 447 1.6E-54 T 21-04-2016 HSISS4_RS04930 db8aba501740a07834276cf31a7704a8 448 SUPERFAMILY SSF55785 320 428 5.23E-6 T 21-04-2016 IPR000014 PAS domain HSISS4_RS03805 c815107aec4edb7fe48cbd810a77fbd9 275 PANTHER PTHR11040:SF33 1 275 7.4E-104 T 21-04-2016 HSISS4_RS03805 c815107aec4edb7fe48cbd810a77fbd9 275 Pfam PF02535 ZIP Zinc transporter 125 270 4.3E-15 T 21-04-2016 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 HSISS4_RS03805 c815107aec4edb7fe48cbd810a77fbd9 275 PANTHER PTHR11040 1 275 7.4E-104 T 21-04-2016 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 Pfam PF08002 Protein of unknown function (DUF1697) 1 130 4.5E-26 T 21-04-2016 IPR012545 Protein of unknown function DUF1697 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 PANTHER PTHR36439 1 181 6.5E-35 T 21-04-2016 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 Gene3D G3DSA:3.30.70.1260 89 179 7.6E-38 T 21-04-2016 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 Gene3D G3DSA:3.30.70.1280 1 87 2.9E-23 T 21-04-2016 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 SUPERFAMILY SSF160379 1 176 6.28E-48 T 21-04-2016 HSISS4_RS04560 c8655273fce94c6a21f37200ef628186 181 PANTHER PTHR36439:SF1 1 181 6.5E-35 T 21-04-2016 HSISS4_RS00875 90439c66553d481112306b1270a38a05 143 PANTHER PTHR10093 1 139 1.4E-42 T 21-04-2016 HSISS4_RS00875 90439c66553d481112306b1270a38a05 143 Pfam PF01592 NifU-like N terminal domain 10 126 3.0E-25 T 21-04-2016 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 HSISS4_RS00875 90439c66553d481112306b1270a38a05 143 Gene3D G3DSA:3.90.1010.10 9 140 1.0E-40 T 21-04-2016 HSISS4_RS00875 90439c66553d481112306b1270a38a05 143 SUPERFAMILY SSF82649 2 139 4.71E-47 T 21-04-2016 HSISS4_RS00875 90439c66553d481112306b1270a38a05 143 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 6 138 9.5E-54 T 21-04-2016 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 1.1E-20 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 288 311 1.1E-20 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 1.1E-20 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 1.1E-20 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 4 324 76.549 T 21-04-2016 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PANTHER PTHR11405:SF44 6 269 4.2E-153 T 21-04-2016 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PANTHER PTHR11405:SF44 289 326 4.2E-153 T 21-04-2016 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 5 145 1.6E-42 T 21-04-2016 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 SUPERFAMILY SSF53671 4 325 3.52E-94 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 Gene3D G3DSA:3.40.50.1370 3 142 6.8E-53 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PANTHER PTHR11405 6 269 4.2E-153 T 21-04-2016 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PANTHER PTHR11405 289 326 4.2E-153 T 21-04-2016 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 320 1.9E-49 T 21-04-2016 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 6.8E-29 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 302 313 6.8E-29 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 6.8E-29 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 222 232 6.8E-29 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 6.8E-29 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 Gene3D G3DSA:3.40.50.1370 143 310 5.8E-64 T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 21-04-2016 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 HSISS4_RS02845 fc6c4691a5c2b254db020a8aed0b06ea 326 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 5 323 1.2E-114 T 21-04-2016 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 129 163 2.6E-6 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 SMART SM01266 5 57 2.1E-15 T 21-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 SUPERFAMILY SSF51161 1 182 3.19E-45 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 92 105 0.0085 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 Gene3D G3DSA:2.160.10.10 3 184 1.2E-54 T 21-04-2016 HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 PANTHER PTHR23416 1 187 1.4E-79 T 21-04-2016 HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 PANTHER PTHR23416:SF58 1 187 1.4E-79 T 21-04-2016 HSISS4_RS06670 1d97515800279730412ac1205bf7cad4 187 Pfam PF12464 Maltose acetyltransferase 7 56 3.8E-10 T 21-04-2016 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 SUPERFAMILY SSF52540 325 571 1.59E-83 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 Gene3D G3DSA:3.40.50.300 331 565 1.2E-72 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 Pfam PF00005 ABC transporter 352 501 1.2E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 Pfam PF00664 ABC transporter transmembrane region 19 287 1.9E-40 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 PANTHER PTHR24221 1 580 9.6E-185 T 21-04-2016 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 SMART SM00382 361 547 1.9E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 Gene3D G3DSA:1.20.1560.10 5 314 9.5E-62 T 21-04-2016 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 SUPERFAMILY SSF90123 5 313 5.89E-69 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS06810 f5f679ba25015b2e54bad34f244a1862 581 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Gene3D G3DSA:3.50.50.60 261 446 1.9E-53 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 380 394 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 176 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 320 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 543 563 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 268 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 151 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 521 536 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 456 477 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 427 2.2E-63 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PANTHER PTHR22912:SF125 126 572 6.4E-176 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PIRSF PIRSF000350 58 569 4.9E-77 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 SUPERFAMILY SSF55424 458 579 7.39E-40 T 21-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PANTHER PTHR22912 126 572 6.4E-176 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Gene3D G3DSA:3.30.390.30 447 578 3.6E-45 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 128 440 6.1E-68 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 162 172 - T 21-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Pfam PF00364 Biotin-requiring enzyme 4 76 1.7E-18 T 21-04-2016 IPR000089 Biotin/lipoyl attachment HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 460 568 2.3E-36 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Gene3D G3DSA:2.40.50.100 1 95 1.9E-27 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 405 427 4.3E-37 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 295 313 4.3E-37 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 149 4.3E-37 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 379 395 4.3E-37 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 274 4.3E-37 T 21-04-2016 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 SUPERFAMILY SSF51230 1 91 2.88E-25 T 21-04-2016 IPR011053 Single hybrid motif HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 Gene3D G3DSA:3.50.50.60 126 260 1.8E-36 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 21-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 127 578 6.3E-160 T 21-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 SUPERFAMILY SSF51905 225 312 1.09E-56 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 SUPERFAMILY SSF51905 341 479 1.09E-56 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS04765 89560ba83e1e3c890c588097eb793afc 584 SUPERFAMILY SSF51905 127 178 1.09E-56 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS01525 6f9055f2e71d5897d20ada92663461ad 147 SUPERFAMILY SSF52540 21 110 2.65E-21 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01525 6f9055f2e71d5897d20ada92663461ad 147 Gene3D G3DSA:3.40.50.300 2 144 3.0E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01525 6f9055f2e71d5897d20ada92663461ad 147 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 5 126 1.7E-33 T 21-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HSISS4_RS01525 6f9055f2e71d5897d20ada92663461ad 147 PANTHER PTHR33540 1 146 1.3E-41 T 21-04-2016 HSISS4_RS01525 6f9055f2e71d5897d20ada92663461ad 147 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 5 130 7.3E-36 T 21-04-2016 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 SUPERFAMILY SSF52540 1 362 2.5E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 366 100.143 T 21-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 Gene3D G3DSA:3.40.50.300 1 166 5.6E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 Gene3D G3DSA:3.40.50.300 234 350 5.6E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 21-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 ProSitePatterns PS00618 RecF protein signature 2. 305 323 - T 21-04-2016 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 349 2.3E-127 T 21-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 PANTHER PTHR32182 1 343 3.6E-69 T 21-04-2016 HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 345 2.7E-14 T 21-04-2016 IPR003395 RecF/RecN/SMC, N-terminal HSISS4_RS09685 c5c14d5e353438c398d601b45ee3ff63 366 PANTHER PTHR32182:SF0 1 343 3.6E-69 T 21-04-2016 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 Gene3D G3DSA:3.30.70.1150 84 158 8.2E-28 T 21-04-2016 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 Pfam PF01842 ACT domain 5 68 3.6E-14 T 21-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 2.7E-54 T 21-04-2016 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 PANTHER PTHR30239 1 157 1.9E-75 T 21-04-2016 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 Gene3D G3DSA:3.30.70.260 1 79 1.6E-26 T 21-04-2016 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 SUPERFAMILY SSF55021 80 158 1.33E-22 T 21-04-2016 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 5.0E-34 T 21-04-2016 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 Pfam PF10369 Small subunit of acetolactate synthase 85 157 5.9E-26 T 21-04-2016 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09110 291c63fe5cffe41a03dbe5ffde78c4d8 158 SUPERFAMILY SSF55021 2 80 2.5E-18 T 21-04-2016 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.4E-15 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.4E-15 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.4E-15 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.4E-15 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 3.0E-9 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 PANTHER PTHR21109 1 56 4.1E-22 T 21-04-2016 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.908 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 56 6.4E-22 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 Pfam PF01165 Ribosomal protein S21 5 56 1.0E-21 T 21-04-2016 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07155 998ba5a4e3f4361a6bf6c50455637f37 58 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 21-04-2016 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02390 39222d0c185869a3df30f18fab8180cc 463 PANTHER PTHR11785 8 455 3.5E-122 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS02390 39222d0c185869a3df30f18fab8180cc 463 ProSitePatterns PS00218 Amino acid permeases signature. 51 81 - T 21-04-2016 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 HSISS4_RS02390 39222d0c185869a3df30f18fab8180cc 463 Pfam PF00324 Amino acid permease 26 454 5.7E-83 T 21-04-2016 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 HSISS4_RS02390 39222d0c185869a3df30f18fab8180cc 463 PIRSF PIRSF006060 4 463 2.5E-61 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS02390 39222d0c185869a3df30f18fab8180cc 463 PANTHER PTHR11785:SF29 8 455 3.5E-122 T 21-04-2016 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SUPERFAMILY SSF50249 4 114 1.94E-12 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Gene3D G3DSA:2.40.50.140 194 274 1.1E-28 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PANTHER PTHR10724:SF6 1 354 3.7E-88 T 21-04-2016 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SUPERFAMILY SSF50249 191 276 3.66E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 110 126 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 292 311 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 214 235 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 331 349 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 157 177 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 17 35 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PRINTS PR00681 Ribosomal protein S1 signature 128 145 1.4E-39 T 21-04-2016 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 PANTHER PTHR10724 1 354 3.7E-88 T 21-04-2016 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SMART SM00316 277 348 3.1E-25 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SMART SM00316 15 91 5.1E-6 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SMART SM00316 105 173 4.1E-8 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SMART SM00316 192 262 1.3E-26 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Pfam PF00575 S1 RNA binding domain 106 173 1.1E-11 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Pfam PF00575 S1 RNA binding domain 190 262 8.0E-22 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Pfam PF00575 S1 RNA binding domain 277 348 1.8E-23 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Pfam PF00575 S1 RNA binding domain 14 74 1.5E-8 T 21-04-2016 IPR003029 S1 domain GO:0003676 HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Gene3D G3DSA:2.40.50.140 9 82 7.5E-12 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Gene3D G3DSA:2.40.50.140 106 174 3.4E-14 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 Gene3D G3DSA:2.40.50.140 275 349 1.6E-29 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SUPERFAMILY SSF50249 262 351 7.09E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02795 44b20fe1fa88aa4388fb9dc292de2465 400 SUPERFAMILY SSF50249 106 186 2.74E-14 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00910 ad81ad2169f20ce75671ee522dbaae30 270 Gene3D G3DSA:1.10.3470.10 45 257 3.6E-7 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS00910 ad81ad2169f20ce75671ee522dbaae30 270 Pfam PF00950 ABC 3 transport family 8 262 1.9E-72 T 21-04-2016 IPR001626 ABC-3 GO:0005524|GO:0006810|GO:0016020|GO:0042626 HSISS4_RS00910 ad81ad2169f20ce75671ee522dbaae30 270 SUPERFAMILY SSF81345 4 257 7.98E-37 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS00910 ad81ad2169f20ce75671ee522dbaae30 270 PANTHER PTHR30477 1 266 3.5E-83 T 21-04-2016 HSISS4_RS00910 ad81ad2169f20ce75671ee522dbaae30 270 PANTHER PTHR30477:SF0 1 266 3.5E-83 T 21-04-2016 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 SUPERFAMILY SSF52172 1 123 4.84E-44 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 SUPERFAMILY SSF46894 131 231 7.31E-30 T 21-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 PANTHER PTHR26402 2 233 2.3E-106 T 21-04-2016 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 SMART SM00862 155 231 1.7E-26 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 Gene3D G3DSA:3.40.50.2300 2 133 2.3E-43 T 21-04-2016 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 PANTHER PTHR26402:SF614 2 233 2.3E-106 T 21-04-2016 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 230 2.9E-27 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 Gene3D G3DSA:1.10.10.10 134 232 2.3E-33 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 SMART SM00448 2 112 3.8E-49 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS04380 05890dd4d0763efcac3206f844e0ff1a 235 Pfam PF00072 Response regulator receiver domain 4 113 1.3E-31 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 PIRSF PIRSF005052 6 291 1.1E-108 T 21-04-2016 IPR005337 RapZ-like family GO:0005524 HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 6 288 41.934 T 21-04-2016 IPR005337 RapZ-like family GO:0005524 HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 SUPERFAMILY SSF52540 8 157 2.75E-12 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 PANTHER PTHR30448 1 295 5.4E-148 T 21-04-2016 HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 Gene3D G3DSA:3.40.50.300 4 163 3.6E-16 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 Pfam PF03668 P-loop ATPase protein family 6 289 1.8E-105 T 21-04-2016 IPR005337 RapZ-like family GO:0005524 HSISS4_RS05540 4f4ca5ea5d8868fc2a85577a0f8350cf 296 PANTHER PTHR30448:SF0 1 295 5.4E-148 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF51445 856 1026 2.52E-22 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 9.1E-8 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Pfam PF01473 Putative cell wall binding repeat 1277 1289 0.28 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Pfam PF01473 Putative cell wall binding repeat 1118 1137 2.9E-5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF69360 1090 1290 3.79E-29 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF69360 1458 1573 4.71E-23 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF69360 181 230 3.66E-10 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1430 1509 2.5E-16 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1167 1241 2.8E-7 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1510 1577 5.9E-14 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1302 1428 2.7E-19 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1524 1576 1.6E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1395 1458 3.7E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1331 1392 7.6E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1460 1521 4.8E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1128 1189 1.2E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:3.20.20.80 883 965 9.6E-17 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 178 228 1.9E-8 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1242 1289 2.2E-11 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:2.10.270.10 1090 1157 4.0E-11 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF51445 640 687 9.6E-31 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF51445 404 603 9.6E-31 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 SUPERFAMILY SSF69360 1300 1493 5.34E-37 T 21-04-2016 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Pfam PF02324 Glycosyl hydrolase family 70 292 1090 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:3.20.20.80 419 607 1.1E-23 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06505 cb6414889338c1bb8e502be70ce87954 1579 Gene3D G3DSA:3.20.20.80 639 692 1.1E-23 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 Gene3D G3DSA:3.40.190.10 227 267 3.1E-28 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 Gene3D G3DSA:3.40.190.10 38 117 3.1E-28 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 SMART SM00062 40 267 3.0E-42 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 PANTHER PTHR18966 28 266 3.6E-21 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 SUPERFAMILY SSF53850 38 266 7.03E-48 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 PANTHER PTHR18966:SF208 28 266 3.6E-21 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 Gene3D G3DSA:3.40.190.10 118 226 9.9E-22 T 21-04-2016 HSISS4_RS01360 38a91fea6e93f0315ff2acfd5122a2d5 282 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 42 265 1.0E-47 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 1.5E-282 T 21-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:2.60.34.10 360 501 1.6E-70 T 21-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 SUPERFAMILY SSF53067 161 351 1.11E-67 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 607 36.151 T 21-04-2016 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 SUPERFAMILY SSF100934 477 576 1.96E-11 T 21-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 21-04-2016 IPR018181 Heat shock protein 70, conserved site HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.30.30.30 39 98 7.6E-12 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.30.420.40 165 199 7.7E-35 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.30.420.40 289 331 7.7E-35 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:1.20.1270.10 502 573 3.4E-18 T 21-04-2016 IPR029048 Heat shock protein 70kD, C-terminal domain HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 172 182 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 358 377 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 439 455 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 112 132 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 53 61 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 335 355 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PRINTS PR00301 70kDa heat shock protein signature 304 320 5.5E-78 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PANTHER PTHR19375 2 606 0.0 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 SUPERFAMILY SSF53067 1 157 2.1E-56 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 SUPERFAMILY SSF100920 354 510 1.44E-60 T 21-04-2016 IPR029047 Heat shock protein 70kD, peptide-binding domain HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.30.420.40 99 164 2.1E-58 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.30.420.40 3 38 2.1E-58 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Pfam PF00012 Hsp70 protein 4 573 2.8E-238 T 21-04-2016 IPR013126 Heat shock protein 70 family HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 Gene3D G3DSA:3.90.640.10 200 285 1.6E-31 T 21-04-2016 HSISS4_RS00675 1690649d9ce0c28c4bd0354b9f05d712 607 PANTHER PTHR19375:SF173 2 606 0.0 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 SUPERFAMILY SSF161098 280 473 6.05E-15 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465:SF0 148 170 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465:SF0 261 491 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465:SF0 62 78 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465:SF0 1 44 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 297 490 1.2E-36 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465 148 170 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465 261 491 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465 62 78 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 PANTHER PTHR30465 1 44 1.3E-82 T 21-04-2016 HSISS4_RS06995 c5750f1ab605413c04e9de0113b00688 497 Gene3D G3DSA:1.10.3720.10 279 482 4.5E-12 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS03615 1b0a5e2e45931cebc340f2fbf4873b3d 89 Pfam PF11364 Protein of unknown function (DUF3165) 1 78 4.5E-31 T 21-04-2016 IPR021506 Protein of unknown function DUF3165 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 SUPERFAMILY SSF69360 135 421 1.91E-26 T 21-04-2016 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 Gene3D G3DSA:2.10.270.10 139 211 7.5E-14 T 21-04-2016 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 Gene3D G3DSA:2.10.270.10 212 305 1.5E-10 T 21-04-2016 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 Pfam PF01473 Putative cell wall binding repeat 197 214 0.014 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 Pfam PF01473 Putative cell wall binding repeat 355 372 0.001 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 206 266 1.4E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 142 205 3.1E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 364 427 3.8E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06540 557a7c524f2d7970a6d8fe8ae63779c9 443 Gene3D G3DSA:2.10.270.10 334 438 2.3E-18 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 PANTHER PTHR21535 12 314 1.9E-84 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 SUPERFAMILY SSF144083 247 312 6.41E-12 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 SUPERFAMILY SSF143865 19 246 2.22E-43 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 Gene3D G3DSA:1.20.58.340 236 314 2.3E-16 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 PANTHER PTHR21535:SF40 12 314 1.9E-84 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 Gene3D G3DSA:3.30.460.20 8 110 1.8E-5 T 21-04-2016 HSISS4_RS08425 e4a0806cf6199bc0b3321f4821597e91 314 Pfam PF01544 CorA-like Mg2+ transporter protein 22 311 1.1E-61 T 21-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 Gene3D G3DSA:3.40.50.1220 85 134 1.6E-8 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 Gene3D G3DSA:3.40.50.1220 2 30 1.6E-8 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 Gene3D G3DSA:3.40.50.1220 203 274 1.6E-8 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 SUPERFAMILY SSF52467 2 275 1.68E-38 T 21-04-2016 IPR029035 DHS-like NAD/FAD-binding domain HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 PANTHER PTHR11085:SF10 4 173 8.1E-20 T 21-04-2016 HSISS4_RS05295 1f41e2f1abc0cccde9e1c73f447cd65a 277 PANTHER PTHR11085 4 173 8.1E-20 T 21-04-2016 IPR003000 Sirtuin family GO:0070403 HSISS4_RS02310 21508f1ee284f5767bb339fe81aa10ec 291 PANTHER PTHR11669 6 160 2.0E-47 T 21-04-2016 HSISS4_RS02310 21508f1ee284f5767bb339fe81aa10ec 291 Gene3D G3DSA:3.40.50.300 7 161 1.7E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02310 21508f1ee284f5767bb339fe81aa10ec 291 SUPERFAMILY SSF52540 8 180 6.91E-34 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02310 21508f1ee284f5767bb339fe81aa10ec 291 Pfam PF13177 DNA polymerase III, delta subunit 7 162 3.4E-51 T 21-04-2016 HSISS4_RS02310 21508f1ee284f5767bb339fe81aa10ec 291 PANTHER PTHR11669:SF8 6 160 2.0E-47 T 21-04-2016 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 SUPERFAMILY SSF52728 169 326 5.62E-48 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 Gene3D G3DSA:3.40.35.10 169 327 4.2E-58 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 Gene3D G3DSA:3.40.50.510 2 142 2.7E-48 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 PANTHER PTHR33799 3 331 2.9E-158 T 21-04-2016 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 PANTHER PTHR33799:SF7 3 331 2.9E-158 T 21-04-2016 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 SUPERFAMILY SSF53062 2 134 7.06E-36 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 Pfam PF03830 PTS system sorbose subfamily IIB component 171 316 2.5E-47 T 21-04-2016 IPR004720 Phosphotransferase system, sorbose subfamily IIB component GO:0005737|GO:0008982|GO:0009401 HSISS4_RS01505 f554348108f5ab3b56eff155fad3cb45 335 Pfam PF03610 PTS system fructose IIA component 4 121 7.8E-34 T 21-04-2016 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 HSISS4_RS00925 4eb1393cdbd5bd0d7a4df7fbc8c4f94d 271 PANTHER PTHR15822 1 268 2.3E-21 T 21-04-2016 HSISS4_RS00925 4eb1393cdbd5bd0d7a4df7fbc8c4f94d 271 SUPERFAMILY SSF56219 1 265 4.06E-35 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS00925 4eb1393cdbd5bd0d7a4df7fbc8c4f94d 271 Gene3D G3DSA:3.60.10.10 1 268 1.5E-25 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS00925 4eb1393cdbd5bd0d7a4df7fbc8c4f94d 271 PANTHER PTHR15822:SF7 1 268 2.3E-21 T 21-04-2016 HSISS4_RS00925 4eb1393cdbd5bd0d7a4df7fbc8c4f94d 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 21 261 2.7E-19 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Gene3D G3DSA:2.120.10.90 495 810 1.1E-65 T 21-04-2016 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 SUPERFAMILY SSF101904 496 811 4.05E-68 T 21-04-2016 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 3 816 33.022 T 21-04-2016 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 SUPERFAMILY SSF56719 27 482 2.49E-166 T 21-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 SMART SM00434 7 460 4.0E-255 T 21-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 467 6.2E-149 T 21-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Gene3D G3DSA:3.90.199.10 26 231 1.5E-116 T 21-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Gene3D G3DSA:3.90.199.10 329 394 1.5E-116 T 21-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 706 745 0.022 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 546 596 4.4E-5 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 505 520 6.7 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 605 650 0.0017 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 653 700 7.7E-15 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 PANTHER PTHR10169 4 737 0.0 T 21-04-2016 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 PANTHER PTHR10169:SF47 4 737 0.0 T 21-04-2016 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 4 742 0.0 T 21-04-2016 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS02770 5f6d9dce0cd80dc1762f1778999d3c2c 818 Gene3D G3DSA:3.30.1360.40 232 328 1.7E-34 T 21-04-2016 IPR024946 Arginine repressor C-terminal-like domain HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 Gene3D G3DSA:3.30.420.40 103 296 1.9E-46 T 21-04-2016 HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 PANTHER PTHR18964 1 294 4.6E-54 T 21-04-2016 HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 SUPERFAMILY SSF53067 1 295 1.04E-44 T 21-04-2016 HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 PANTHER PTHR18964:SF133 1 294 4.6E-54 T 21-04-2016 HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 Pfam PF00480 ROK family 4 154 3.6E-24 T 21-04-2016 IPR000600 ROK family HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 Pfam PF00480 ROK family 200 296 2.8E-10 T 21-04-2016 IPR000600 ROK family HSISS4_RS07320 e473933b42cb486aee2367142d3ed7b8 297 Gene3D G3DSA:3.30.420.40 1 100 3.4E-27 T 21-04-2016 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PANTHER PTHR22594:SF4 1 496 6.7E-273 T 21-04-2016 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 Gene3D G3DSA:3.30.930.10 151 494 3.0E-122 T 21-04-2016 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 15 496 43.681 T 21-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PANTHER PTHR22594 1 496 6.7E-273 T 21-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 Pfam PF00152 tRNA synthetases class II (D, K and N) 157 495 6.8E-80 T 21-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PIRSF PIRSF039101 2 496 3.6E-194 T 21-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 Pfam PF01336 OB-fold nucleic acid binding domain 64 138 9.0E-15 T 21-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 9 496 2.3E-211 T 21-04-2016 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 SUPERFAMILY SSF55681 156 495 1.88E-120 T 21-04-2016 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 Gene3D G3DSA:2.40.50.140 10 149 2.2E-50 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 209 225 1.7E-38 T 21-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 380 396 1.7E-38 T 21-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 193 203 1.7E-38 T 21-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 256 273 1.7E-38 T 21-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 PRINTS PR00982 Lysyl-tRNA synthetase signature 238 251 1.7E-38 T 21-04-2016 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 HSISS4_RS03410 af6d403777980ea5c619dd9cf56fb8a8 496 SUPERFAMILY SSF50249 8 149 1.64E-44 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 Pfam PF00578 AhpC/TSA family 4 132 8.7E-34 T 21-04-2016 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15 HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 TIGRFAM TIGR03137 AhpC: peroxiredoxin 2 186 1.3E-101 T 21-04-2016 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 PIRSF PIRSF000239 1 186 4.1E-52 T 21-04-2016 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15 HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 PANTHER PTHR10681 2 186 5.0E-88 T 21-04-2016 HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 PANTHER PTHR10681:SF121 2 186 5.0E-88 T 21-04-2016 HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 SUPERFAMILY SSF52833 3 186 9.35E-55 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 Gene3D G3DSA:3.40.30.10 3 182 1.6E-59 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00470 40dbff4671a2d2e541a29f6b8826ff12 186 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 181 4.2E-5 T 21-04-2016 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 Gene3D G3DSA:3.40.50.1240 1 189 6.1E-47 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 PANTHER PTHR23029 1 193 1.3E-44 T 21-04-2016 HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 PANTHER PTHR23029:SF38 1 193 1.3E-44 T 21-04-2016 HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 21-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 189 1.6E-38 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 SUPERFAMILY SSF53254 1 185 1.28E-46 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04670 bea6011cd9369dbfa2144b94871a8886 200 SMART SM00855 2 155 1.6E-20 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 PANTHER PTHR33154 13 108 2.3E-15 T 21-04-2016 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 SMART SM00450 121 217 4.3E-16 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 SUPERFAMILY SSF46785 12 107 3.63E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 SMART SM00418 18 96 9.8E-19 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.1E-6 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 2.1E-6 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.1E-6 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 Gene3D G3DSA:3.40.250.10 118 212 4.8E-22 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 SUPERFAMILY SSF52821 114 212 1.57E-24 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 Pfam PF00581 Rhodanese-like domain 129 212 2.2E-14 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 Pfam PF01022 Bacterial regulatory protein, arsR family 25 69 5.4E-12 T 21-04-2016 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 HSISS4_RS00580 c0cdda2788024a93d247ef60afbb9d05 222 Gene3D G3DSA:1.10.10.10 7 97 2.1E-21 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 SMART SM00304 164 216 4.6E-6 T 21-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 Gene3D G3DSA:3.30.565.10 302 433 4.6E-8 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 SUPERFAMILY SSF55874 301 433 4.93E-13 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 295 1.0E-8 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 Gene3D G3DSA:1.10.287.130 226 292 8.6E-12 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 Pfam PF00672 HAMP domain 147 211 1.3E-10 T 21-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 SUPERFAMILY SSF47384 216 294 8.04E-11 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 SUPERFAMILY SSF158472 164 215 3.01E-7 T 21-04-2016 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 SMART SM00388 231 297 7.7E-9 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 PANTHER PTHR24423 158 379 7.6E-20 T 21-04-2016 HSISS4_RS06410 262cfd88ab4096a9a4fe253469c6bf76 434 PANTHER PTHR24423 1 7 7.6E-20 T 21-04-2016 HSISS4_RS06220 8324f335d4861380a6d520a01ee69aa9 848 Pfam PF14262 Domain of unknown function (DUF4353) 227 451 4.7E-29 T 21-04-2016 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HSISS4_RS06220 8324f335d4861380a6d520a01ee69aa9 848 Pfam PF00746 Gram positive anchor 808 844 6.6E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 PANTHER PTHR11014 4 377 5.5E-202 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 PANTHER PTHR11014:SF98 4 377 5.5E-202 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 5 363 2.8E-89 T 21-04-2016 IPR017439 Amidohydrolase GO:0016787 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 SUPERFAMILY SSF55031 174 290 3.66E-30 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Gene3D G3DSA:3.40.630.10 4 171 5.2E-73 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Gene3D G3DSA:3.40.630.10 292 365 5.2E-73 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 SUPERFAMILY SSF53187 292 365 2.9E-66 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 SUPERFAMILY SSF53187 4 190 2.9E-66 T 21-04-2016 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 PIRSF PIRSF005962 1 375 9.5E-99 T 21-04-2016 IPR017439 Amidohydrolase GO:0016787 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Gene3D G3DSA:3.30.70.360 174 291 1.5E-39 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Pfam PF07687 Peptidase dimerisation domain 175 273 8.5E-11 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Pfam PF01546 Peptidase family M20/M25/M40 68 370 2.5E-23 T 21-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HSISS4_RS08925 a5f0d4ab24fdaa36d80ac929bcbdd18d 377 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 2 374 63.347 T 21-04-2016 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941|UniPathway: UPA00034 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PANTHER PTHR11946 3 624 5.0E-298 T 21-04-2016 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 SUPERFAMILY SSF50249 563 664 1.0E-27 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Pfam PF01588 Putative tRNA binding domain 570 664 5.6E-23 T 21-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Pfam PF09334 tRNA synthetases class I (M) 5 375 6.3E-118 T 21-04-2016 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Gene3D G3DSA:3.40.50.620 235 349 2.7E-73 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Gene3D G3DSA:3.40.50.620 3 113 2.7E-73 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 271 286 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 363 374 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PRINTS PR01041 Methionyl-tRNA synthetase signature 233 244 1.5E-33 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 SUPERFAMILY SSF47323 365 577 1.72E-45 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 SUPERFAMILY SSF52374 3 366 8.58E-108 T 21-04-2016 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Gene3D G3DSA:1.10.730.10 352 523 5.6E-53 T 21-04-2016 IPR009080 Aminoacyl-tRNA synthetase, class 1a, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 PANTHER PTHR11946:SF1 3 624 5.0E-298 T 21-04-2016 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 522 49.558 T 21-04-2016 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Gene3D G3DSA:2.40.50.140 557 666 1.1E-37 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 Gene3D G3DSA:2.170.220.10 116 234 4.1E-46 T 21-04-2016 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 537 666 3.0E-38 T 21-04-2016 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 HSISS4_RS02060 c44eb60d1495b075f693cbf29f022c91 667 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 498 3.0E-176 T 21-04-2016 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: REACT_71 HSISS4_RS05845 3abab13d69337e2db91a4cc15be2d70e 133 SUPERFAMILY SSF54593 4 133 1.48E-29 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS05845 3abab13d69337e2db91a4cc15be2d70e 133 Gene3D G3DSA:3.10.180.10 8 133 2.0E-35 T 21-04-2016 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase HSISS4_RS05845 3abab13d69337e2db91a4cc15be2d70e 133 ProSitePatterns PS00934 Glyoxalase I signature 1. 8 29 - T 21-04-2016 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|UniPathway: UPA00619 HSISS4_RS05845 3abab13d69337e2db91a4cc15be2d70e 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 131 8.7E-18 T 21-04-2016 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360:SF2 6 146 1.3E-77 T 21-04-2016 HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360 6 146 1.3E-77 T 21-04-2016 HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 Gene3D G3DSA:3.30.70.1290 3 133 4.6E-56 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 Pfam PF01797 Transposase IS200 like 13 130 1.3E-37 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 SUPERFAMILY SSF143422 6 130 5.76E-46 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06650 80999fee64742c6a0f52f776b5d054ac 157 SMART SM01321 12 130 1.5E-42 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360:SF2 6 146 1.3E-77 T 21-04-2016 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360 6 146 1.3E-77 T 21-04-2016 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 Gene3D G3DSA:3.30.70.1290 3 133 4.6E-56 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 Pfam PF01797 Transposase IS200 like 13 130 1.3E-37 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 SUPERFAMILY SSF143422 6 130 5.76E-46 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS05760 80999fee64742c6a0f52f776b5d054ac 157 SMART SM01321 12 130 1.5E-42 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360:SF2 6 146 1.3E-77 T 21-04-2016 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 PANTHER PTHR33360 6 146 1.3E-77 T 21-04-2016 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 Gene3D G3DSA:3.30.70.1290 3 133 4.6E-56 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 Pfam PF01797 Transposase IS200 like 13 130 1.3E-37 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 SUPERFAMILY SSF143422 6 130 5.76E-46 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS02605 80999fee64742c6a0f52f776b5d054ac 157 SMART SM01321 12 130 1.5E-42 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 215 1.2E-77 T 21-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 2 291 18.807 T 21-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 178 232 1.4E-10 T 21-04-2016 IPR032819 tRNA pseudouridylate synthase B, C-terminal HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 24 177 2.7E-57 T 21-04-2016 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 SUPERFAMILY SSF55120 2 230 2.22E-77 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 PANTHER PTHR13767 2 291 4.5E-115 T 21-04-2016 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS04925 fc6449e77b22f66a24d30b62142ef491 293 PANTHER PTHR13767:SF2 2 291 4.5E-115 T 21-04-2016 HSISS4_RS00810 83554e607e35706747ab141f50d3e019 385 Pfam PF07690 Major Facilitator Superfamily 11 312 2.3E-24 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS00810 83554e607e35706747ab141f50d3e019 385 SUPERFAMILY SSF103473 9 384 1.1E-36 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS00810 83554e607e35706747ab141f50d3e019 385 Gene3D G3DSA:1.20.1250.20 205 377 3.2E-10 T 21-04-2016 HSISS4_RS00810 83554e607e35706747ab141f50d3e019 385 Gene3D G3DSA:1.20.1250.20 9 192 2.8E-19 T 21-04-2016 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 PIRSF PIRSF006293 2 215 5.0E-77 T 21-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 PANTHER PTHR11587 1 210 4.0E-96 T 21-04-2016 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 216 49.243 T 21-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 PANTHER PTHR11587:SF3 1 210 4.0E-96 T 21-04-2016 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 SUPERFAMILY SSF52402 5 213 2.65E-67 T 21-04-2016 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 Gene3D G3DSA:3.40.50.620 4 212 1.2E-80 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 Pfam PF06508 Queuosine biosynthesis protein QueC 6 210 8.2E-84 T 21-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05570 d44c5a76f68c94064ff39b6efe1de923 217 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 203 1.3E-79 T 21-04-2016 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 SUPERFAMILY SSF51735 227 359 2.23E-19 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Gene3D G3DSA:3.30.70.1450 379 447 3.9E-11 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Gene3D G3DSA:3.30.70.1450 154 221 3.6E-10 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Pfam PF02080 TrkA-C domain 152 220 1.8E-11 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Pfam PF02080 TrkA-C domain 383 447 2.1E-12 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 SUPERFAMILY SSF51735 1 149 9.32E-34 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PANTHER PTHR13789 302 342 3.7E-44 T 21-04-2016 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PANTHER PTHR13789 1 167 3.7E-44 T 21-04-2016 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 SUPERFAMILY SSF116726 372 447 4.45E-14 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.7E-11 T 21-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.7E-11 T 21-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.7E-11 T 21-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.7E-11 T 21-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.7E-11 T 21-04-2016 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Pfam PF02254 TrkA-N domain 3 122 2.8E-24 T 21-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Pfam PF02254 TrkA-N domain 229 343 4.1E-15 T 21-04-2016 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Gene3D G3DSA:3.40.50.720 1 149 6.4E-41 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PANTHER PTHR13789:SF225 302 342 3.7E-44 T 21-04-2016 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 PANTHER PTHR13789:SF225 1 167 3.7E-44 T 21-04-2016 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 SUPERFAMILY SSF116726 135 217 8.11E-13 T 21-04-2016 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 HSISS4_RS01265 9ddf0eba8d688b34b028e44f59c56d75 449 Gene3D G3DSA:3.40.50.720 225 358 1.3E-22 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06355 82b79249f46d4f61e5e6befb7512bf20 361 Gene3D G3DSA:1.25.40.10 22 77 1.7E-7 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS06355 82b79249f46d4f61e5e6befb7512bf20 361 Gene3D G3DSA:1.25.40.10 110 167 1.7E-7 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS06355 82b79249f46d4f61e5e6befb7512bf20 361 SUPERFAMILY SSF48452 27 63 2.38E-8 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS06355 82b79249f46d4f61e5e6befb7512bf20 361 SUPERFAMILY SSF48452 111 215 2.38E-8 T 21-04-2016 IPR011990 Tetratricopeptide-like helical domain GO:0005515 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 SUPERFAMILY SSF64182 338 639 2.75E-65 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 Pfam PF02272 DHHA1 domain 586 641 1.6E-7 T 21-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 PANTHER PTHR12112:SF18 604 616 2.2E-73 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 PANTHER PTHR12112:SF18 1 519 2.2E-73 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 Gene3D G3DSA:3.90.1640.10 338 527 4.9E-42 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 PIRSF PIRSF026583 1 654 8.5E-238 T 21-04-2016 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 PANTHER PTHR12112 604 616 2.2E-73 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 PANTHER PTHR12112 1 519 2.2E-73 T 21-04-2016 HSISS4_RS09610 55d535148317db0061abc4f8fd67e449 654 Pfam PF01368 DHH family 339 494 2.1E-19 T 21-04-2016 IPR001667 DDH domain HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 SUPERFAMILY SSF53187 4 81 1.1E-57 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 SUPERFAMILY SSF53187 174 352 1.1E-57 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 Gene3D G3DSA:2.40.30.40 75 164 5.3E-27 T 21-04-2016 IPR023367 Peptidase M42, domain 2 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 Pfam PF05343 M42 glutamyl aminopeptidase 45 334 1.2E-95 T 21-04-2016 IPR008007 Peptidase M42 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 SUPERFAMILY SSF101821 71 182 4.88E-26 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 Gene3D G3DSA:3.40.630.10 2 74 9.6E-76 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 Gene3D G3DSA:3.40.630.10 171 354 9.6E-76 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 PANTHER PTHR32481:SF0 1 355 2.3E-150 T 21-04-2016 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 TIGRFAM TIGR03107 glu_aminopep: glutamyl aminopeptidase 5 353 2.8E-204 T 21-04-2016 IPR017538 Peptidase M42, glutamyl aminopeptidase MetaCyc: PWY-5706|MetaCyc: PWY-5707|MetaCyc: PWY-7614 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 PIRSF PIRSF001123 1 355 3.8E-133 T 21-04-2016 IPR008007 Peptidase M42 HSISS4_RS09005 b6b3065a527a939876d00ee138c47276 355 PANTHER PTHR32481 1 355 2.3E-150 T 21-04-2016 HSISS4_RS08955 34d2cfd98a785029b0fdb53557c2e3d4 55 TIGRFAM TIGR03949 bact_IIb_cerein: class IIb bacteriocin, lactobin A/cerein 7B family 9 48 3.9E-13 T 21-04-2016 IPR023991 Bacteriocin, class IIb, lactobin A/cerein 7B family HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 Gene3D G3DSA:3.40.50.300 3 231 4.3E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 SUPERFAMILY SSF52540 4 233 4.42E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 PANTHER PTHR24220 4 249 5.8E-90 T 21-04-2016 HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 PANTHER PTHR24220:SF309 4 249 5.8E-90 T 21-04-2016 HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 Pfam PF00005 ABC transporter 18 167 3.3E-38 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03190 ee5e97de2a00202bf3894789284a9098 251 SMART SM00382 27 212 8.8E-12 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08295 ef7799d4f0f1f62b7deafb39ce431e14 202 Pfam PF11188 Protein of unknown function (DUF2975) 102 202 6.0E-7 T 21-04-2016 IPR021354 Protein of unknown function DUF2975 HSISS4_RS04705 48933e48c43e1bca50a4bf5352b187a7 206 Gene3D G3DSA:3.40.50.1110 21 204 2.6E-44 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS04705 48933e48c43e1bca50a4bf5352b187a7 206 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 34 195 3.7E-20 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS04705 48933e48c43e1bca50a4bf5352b187a7 206 SUPERFAMILY SSF52266 8 204 3.21E-44 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS04705 48933e48c43e1bca50a4bf5352b187a7 206 PANTHER PTHR30383 32 206 3.4E-18 T 21-04-2016 HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 PANTHER PTHR24220:SF85 5 255 2.6E-129 T 21-04-2016 HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 SUPERFAMILY SSF52540 3 231 1.08E-42 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 Pfam PF00005 ABC transporter 19 171 7.6E-23 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 SMART SM00382 28 230 5.7E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 PANTHER PTHR24220 5 255 2.6E-129 T 21-04-2016 HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 Gene3D G3DSA:3.40.50.300 3 237 4.3E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00860 b48396b0b4abeff18c0e964cd61d3749 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 244 7.6E-110 T 21-04-2016 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 HSISS4_RS09620 0913ae5515585f167c4a7edbf81eadfb 203 PANTHER PTHR33508 1 195 7.4E-54 T 21-04-2016 HSISS4_RS09620 0913ae5515585f167c4a7edbf81eadfb 203 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 195 8.3E-46 T 21-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HSISS4_RS09620 0913ae5515585f167c4a7edbf81eadfb 203 Pfam PF01914 MarC family integral membrane protein 4 201 6.7E-50 T 21-04-2016 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 HSISS4_RS09620 0913ae5515585f167c4a7edbf81eadfb 203 PANTHER PTHR33508:SF1 1 195 7.4E-54 T 21-04-2016 HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 Gene3D G3DSA:3.40.50.1000 1 73 1.9E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 Gene3D G3DSA:3.40.50.1000 171 270 1.9E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 265 2.2E-59 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 3.7E-51 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 PANTHER PTHR10000:SF23 1 270 4.1E-87 T 21-04-2016 HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 237 1.0E-26 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 SUPERFAMILY SSF56784 1 269 1.77E-61 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01515 e06b75b58ae86f1ec59a6238bd92a8e7 270 PANTHER PTHR10000 1 270 4.1E-87 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PANTHER PTHR30408 174 501 5.8E-134 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 Pfam PF12161 HsdM N-terminal domain 10 162 1.2E-19 T 21-04-2016 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 Gene3D G3DSA:3.40.50.150 198 431 3.0E-34 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 SUPERFAMILY SSF53335 9 47 4.3E-126 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 SUPERFAMILY SSF53335 89 515 4.3E-126 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 300 306 - T 21-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PANTHER PTHR30408:SF4 174 501 5.8E-134 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 Pfam PF02384 N-6 DNA Methylase 173 481 1.6E-104 T 21-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 10 483 2.3E-107 T 21-04-2016 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 297 309 1.4E-12 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 1.4E-12 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 196 212 1.4E-12 T 21-04-2016 HSISS4_RS03510 56687dba34219bbaa13bc6c7a47f2f82 533 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 333 357 1.4E-12 T 21-04-2016 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 239 301 1.7E-9 T 21-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 PANTHER PTHR24220:SF503 10 350 3.1E-189 T 21-04-2016 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 SUPERFAMILY SSF52540 8 258 1.89E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 PANTHER PTHR24220 10 350 3.1E-189 T 21-04-2016 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 Gene3D G3DSA:3.40.50.300 3 266 5.3E-69 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 322 2.5E-15 T 21-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 Pfam PF00005 ABC transporter 29 187 5.8E-29 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 SMART SM00382 37 237 1.3E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06985 0137b5c40f3a88441327ce9fc0d6100d 361 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 PANTHER PTHR24220:SF0 6 234 1.5E-91 T 21-04-2016 HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 PANTHER PTHR24220 6 234 1.5E-91 T 21-04-2016 HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 SMART SM00382 29 208 3.6E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 Gene3D G3DSA:3.40.50.300 2 225 3.9E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 SUPERFAMILY SSF52540 4 224 1.6E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05185 5ce74ba9ef67f11ec22c051d6ed080f9 238 Pfam PF00005 ABC transporter 20 161 1.0E-28 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 SMART SM01387 8 88 5.9E-46 T 21-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 Pfam PF00312 Ribosomal protein S15 8 88 5.2E-34 T 21-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 2.0E-39 T 21-04-2016 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 21-04-2016 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 Gene3D G3DSA:1.10.287.10 3 89 1.9E-38 T 21-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.754 T 21-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 SUPERFAMILY SSF47060 3 89 3.53E-34 T 21-04-2016 IPR009068 S15/NS1, RNA-binding Reactome: REACT_71 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.3E-36 T 21-04-2016 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00815 b4ee47b943e583affefc3273ecceb983 89 PANTHER PTHR23321 1 89 2.8E-43 T 21-04-2016 HSISS4_RS07090 8c7fc9ec5850d841829cc89846cbb56d 382 SUPERFAMILY SSF53756 5 380 1.2E-25 T 21-04-2016 HSISS4_RS07090 8c7fc9ec5850d841829cc89846cbb56d 382 Pfam PF09314 Domain of unknown function (DUF1972) 1 185 4.5E-102 T 21-04-2016 IPR015393 Domain of unknown function DUF1972 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 Gene3D G3DSA:1.20.1250.20 15 196 8.9E-25 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 Gene3D G3DSA:1.20.1250.20 262 458 1.6E-19 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 Pfam PF07690 Major Facilitator Superfamily 19 408 5.1E-43 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 PANTHER PTHR23501 13 452 1.0E-72 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 SUPERFAMILY SSF103473 9 194 1.57E-53 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 SUPERFAMILY SSF103473 247 458 1.57E-53 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 9.6E-9 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 9.6E-9 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 9.6E-9 T 21-04-2016 HSISS4_RS06660 6f577af1b79a9ff86e7bb266897d211e 461 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 9.6E-9 T 21-04-2016 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 6.8E-14 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 6.8E-14 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 6.8E-14 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 SUPERFAMILY SSF46894 140 210 6.8E-24 T 21-04-2016 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 Gene3D G3DSA:1.10.10.10 150 208 4.2E-29 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 Pfam PF00072 Response regulator receiver domain 7 118 4.1E-23 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 PANTHER PTHR26402 5 205 4.3E-83 T 21-04-2016 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 SMART SM00448 5 118 2.4E-26 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 203 4.6E-21 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 SUPERFAMILY SSF52172 4 130 7.4E-32 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 PANTHER PTHR26402:SF151 5 205 4.3E-83 T 21-04-2016 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 SMART SM00421 146 203 3.4E-26 T 21-04-2016 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 HSISS4_RS06895 f71a234219f6cec5cefad493ba831bc0 214 Gene3D G3DSA:3.40.50.2300 3 149 3.2E-37 T 21-04-2016 HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 SUPERFAMILY SSF74942 86 156 4.97E-18 T 21-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 Pfam PF02576 Putative ribosome maturation factor RimP 19 153 3.2E-37 T 21-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 PANTHER PTHR33867:SF1 1 156 2.7E-41 T 21-04-2016 HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 SUPERFAMILY SSF75420 2 85 7.98E-25 T 21-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 Gene3D G3DSA:2.30.30.180 89 155 1.1E-27 T 21-04-2016 IPR028998 Ribosome maturation factor RimP, C-terminal HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 3 157 21.263 T 21-04-2016 IPR003728 Ribosome maturation factor RimP GO:0042274 HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 PANTHER PTHR33867 1 156 2.7E-41 T 21-04-2016 HSISS4_RS01540 d014f87cd31bb8ccef8a192e74f4e5cd 157 Gene3D G3DSA:3.30.300.70 2 82 1.1E-24 T 21-04-2016 IPR028989 Ribosome maturation factor RimP, N-terminal HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 Pfam PF08353 Domain of unknown function (DUF1727) 319 429 2.9E-30 T 21-04-2016 IPR013564 Domain of unknown function DUF1727 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 PANTHER PTHR23135 31 223 6.6E-130 T 21-04-2016 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 PANTHER PTHR23135 253 447 6.6E-130 T 21-04-2016 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 PANTHER PTHR23135:SF7 31 223 6.6E-130 T 21-04-2016 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 PANTHER PTHR23135:SF7 253 447 6.6E-130 T 21-04-2016 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 SUPERFAMILY SSF53623 39 192 4.89E-34 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 SUPERFAMILY SSF53623 224 296 4.89E-34 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 Gene3D G3DSA:3.40.1190.10 223 298 2.9E-41 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 Gene3D G3DSA:3.40.1190.10 38 189 2.9E-41 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS03770 435cb5904ceec506e602fc1e32b923eb 447 Pfam PF08245 Mur ligase middle domain 53 281 1.7E-13 T 21-04-2016 IPR013221 Mur ligase, central GO:0005524|GO:0009058 UniPathway: UPA00219 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 Pfam PF00699 Urease beta subunit 3 100 2.0E-41 T 21-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 PANTHER PTHR33569:SF1 1 103 1.4E-55 T 21-04-2016 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 SUPERFAMILY SSF51278 1 103 2.22E-44 T 21-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 103 1.7E-45 T 21-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 Hamap MF_01954 Urease subunit beta [ureB]. 1 102 31.625 T 21-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 PANTHER PTHR33569 1 103 1.4E-55 T 21-04-2016 HSISS4_RS01315 3dfa0356961e5cf2b95746eaef9470ba 103 Gene3D G3DSA:2.10.150.10 1 103 2.3E-47 T 21-04-2016 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704|UniPathway: UPA00258 HSISS4_RS02830 b94d45261b28e487d5b42419df1e4075 100 Gene3D G3DSA:3.40.1720.10 1 98 1.3E-42 T 21-04-2016 HSISS4_RS02830 b94d45261b28e487d5b42419df1e4075 100 Pfam PF08860 Domain of unknown function (DUF1827) 1 97 2.1E-36 T 21-04-2016 IPR014959 Protein of unknown function DUF1827 HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 SUPERFAMILY SSF46689 102 142 4.78E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 PANTHER PTHR33498:SF1 1 414 1.6E-107 T 21-04-2016 HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 Pfam PF01610 Transposase 157 400 4.9E-47 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 6.2E-10 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 PANTHER PTHR33498 1 414 1.6E-107 T 21-04-2016 HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 Gene3D G3DSA:1.10.10.60 106 139 2.5E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS04355 8f755dbde66633dab5d5b84e561f0691 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 1.2E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Gene3D G3DSA:3.30.499.10 18 240 6.1E-74 T 21-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 14 884 0.0 T 21-04-2016 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Pfam PF00330 Aconitase family (aconitate hydratase) 73 559 1.2E-175 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Gene3D G3DSA:3.20.19.10 634 882 3.6E-71 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 SUPERFAMILY SSF52016 628 883 8.44E-77 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 ProSitePatterns PS00450 Aconitase family signature 1. 424 440 - T 21-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 141 154 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 270 283 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 165 173 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 194 207 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 428 439 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 363 377 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 490 503 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 208 223 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PRINTS PR00415 Aconitase family signature 284 297 4.1E-40 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670 745 887 0.0 T 21-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670 413 708 0.0 T 21-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670 2 384 0.0 T 21-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 SUPERFAMILY SSF53732 4 623 1.23E-215 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 ProSitePatterns PS01244 Aconitase family signature 2. 490 503 - T 21-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Pfam PF00694 Aconitase C-terminal domain 687 813 2.5E-43 T 21-04-2016 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670:SF1 745 887 0.0 T 21-04-2016 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670:SF1 413 708 0.0 T 21-04-2016 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 PANTHER PTHR11670:SF1 2 384 0.0 T 21-04-2016 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Gene3D G3DSA:3.40.1060.10 241 358 6.1E-37 T 21-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Gene3D G3DSA:3.30.499.10 416 571 1.7E-62 T 21-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS03690 947797369711083d81f32d2c81a8e02b 887 Gene3D G3DSA:3.30.499.10 359 384 1.7E-62 T 21-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 SUPERFAMILY SSF55031 188 383 6.76E-54 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 Pfam PF01546 Peptidase family M20/M25/M40 86 464 2.8E-31 T 21-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 13 463 1.8E-171 T 21-04-2016 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 KEGG: 00480+3.4.13.- HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 116 155 - T 21-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 TIGRFAM TIGR01886 dipeptidase: dipeptidase PepV 2 468 2.1E-215 T 21-04-2016 IPR011291 Peptidase M20A, peptidase V KEGG: 00480+3.4.13.- HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 PANTHER PTHR11014 1 192 1.4E-58 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 PANTHER PTHR11014 260 468 1.4E-58 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 SUPERFAMILY SSF53187 2 188 2.46E-66 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 SUPERFAMILY SSF53187 385 467 2.46E-66 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 82 91 - T 21-04-2016 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 Gene3D G3DSA:3.30.70.360 206 284 4.6E-29 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 Gene3D G3DSA:3.40.630.10 384 467 8.0E-68 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 Gene3D G3DSA:3.40.630.10 4 188 8.0E-68 T 21-04-2016 HSISS4_RS04530 2a6d82110f517f8eed52f8593bf92364 468 Gene3D G3DSA:3.30.70.360 285 382 7.8E-38 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 SUPERFAMILY SSF52540 4 161 1.03E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PANTHER PTHR21087 4 160 2.2E-44 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 Gene3D G3DSA:3.40.50.300 4 161 2.9E-44 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 ProSitePatterns PS01128 Shikimate kinase signature. 52 78 - T 21-04-2016 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PANTHER PTHR21087:SF0 4 160 2.2E-44 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PRINTS PR01100 Shikimate kinase family signature 92 109 8.8E-18 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PRINTS PR01100 Shikimate kinase family signature 23 36 8.8E-18 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PRINTS PR01100 Shikimate kinase family signature 70 79 8.8E-18 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PRINTS PR01100 Shikimate kinase family signature 3 18 8.8E-18 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 PRINTS PR01100 Shikimate kinase family signature 51 59 8.8E-18 T 21-04-2016 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 Pfam PF01202 Shikimate kinase 9 158 1.1E-40 T 21-04-2016 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03045 4af4159dabaf0f405993ef9411233f8b 163 Hamap MF_00109 Shikimate kinase [aroK]. 1 161 24.154 T 21-04-2016 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS09050 a96c646856f2d8080ffda934d9e6228c 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 23 6.0E-4 T 21-04-2016 IPR012902 Prokaryotic N-terminal methylation site HSISS4_RS09050 a96c646856f2d8080ffda934d9e6228c 145 Pfam PF15980 Putative Competence protein ComGF 39 134 4.2E-28 T 21-04-2016 IPR016977 Competence operon G, ComGF HSISS4_RS09050 a96c646856f2d8080ffda934d9e6228c 145 PIRSF PIRSF031611 1 145 4.6E-60 T 21-04-2016 IPR016977 Competence operon G, ComGF HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 SMART SM00739 2 29 6.4E-6 T 21-04-2016 IPR005824 KOW HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 Gene3D G3DSA:2.30.30.30 1 89 6.8E-21 T 21-04-2016 IPR014722 Ribosomal protein L2 domain 2 HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 SUPERFAMILY SSF50104 2 99 3.35E-30 T 21-04-2016 IPR008991 Translation protein SH3-like domain HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 Pfam PF00467 KOW motif 5 36 3.1E-7 T 21-04-2016 IPR005824 KOW HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 94 19.436 T 21-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 PANTHER PTHR12903 1 101 1.8E-40 T 21-04-2016 HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 21-04-2016 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 3 99 9.6E-34 T 21-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09295 2d2094ef03d1c0c5e63796f28b95440a 101 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 99 2.5E-24 T 21-04-2016 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08775 34635f8c79bd0bfdd28296465852af41 187 SUPERFAMILY SSF52218 1 187 2.95E-46 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS08775 34635f8c79bd0bfdd28296465852af41 187 Pfam PF02525 Flavodoxin-like fold 1 182 1.7E-37 T 21-04-2016 IPR003680 Flavodoxin-like fold HSISS4_RS08775 34635f8c79bd0bfdd28296465852af41 187 PANTHER PTHR10204:SF40 1 186 2.9E-38 T 21-04-2016 HSISS4_RS08775 34635f8c79bd0bfdd28296465852af41 187 PANTHER PTHR10204 1 186 2.9E-38 T 21-04-2016 HSISS4_RS08775 34635f8c79bd0bfdd28296465852af41 187 Gene3D G3DSA:3.40.50.360 1 187 8.2E-48 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 34.138 T 21-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 Pfam PF00411 Ribosomal protein S11 17 126 4.6E-52 T 21-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 21-04-2016 IPR018102 Ribosomal S11, conserved site HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 PIRSF PIRSF002131 2 127 1.4E-52 T 21-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 PANTHER PTHR11759 8 127 1.0E-71 T 21-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 5.6E-59 T 21-04-2016 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 Gene3D G3DSA:3.30.420.80 5 127 1.8E-56 T 21-04-2016 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09230 25c9d0701472162ce78dbb35283def9c 127 SUPERFAMILY SSF53137 12 127 1.5E-49 T 21-04-2016 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 442 1.6E-79 T 21-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 8 447 1.4E-141 T 21-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 448 40.103 T 21-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 Gene3D G3DSA:2.40.50.140 11 112 2.9E-25 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PANTHER PTHR22594 4 448 9.5E-186 T 21-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 SUPERFAMILY SSF55681 121 442 2.7E-89 T 21-04-2016 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 Pfam PF01336 OB-fold nucleic acid binding domain 20 106 8.7E-14 T 21-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 207 220 9.0E-15 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 403 417 9.0E-15 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 9.0E-15 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PRINTS PR01042 Aspartyl-tRNA synthetase signature 363 379 9.0E-15 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 SUPERFAMILY SSF50249 12 113 2.35E-19 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 Gene3D G3DSA:3.30.930.10 113 447 3.4E-106 T 21-04-2016 HSISS4_RS05590 87a4eeb7fc59488ee49ed3c9c69d6e1c 448 PANTHER PTHR22594:SF16 4 448 9.5E-186 T 21-04-2016 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22|Reactome: REACT_71 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 21-04-2016 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 Pfam PF00216 Bacterial DNA-binding protein 3 91 1.4E-34 T 21-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 Gene3D G3DSA:4.10.520.10 3 91 6.3E-38 T 21-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 SMART SM00411 2 91 8.6E-47 T 21-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 2.4E-21 T 21-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 2.4E-21 T 21-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 2.4E-21 T 21-04-2016 IPR000119 Histone-like DNA-binding protein GO:0003677 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 PANTHER PTHR33175 1 91 2.6E-44 T 21-04-2016 HSISS4_RS04100 832c797944d6e7452117dfdc786fdb71 91 SUPERFAMILY SSF47729 3 91 1.07E-32 T 21-04-2016 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 7.4E-12 T 21-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 7.4E-12 T 21-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 7.4E-12 T 21-04-2016 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 SUPERFAMILY SSF55957 357 447 9.81E-25 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 SUPERFAMILY SSF53738 155 256 2.12E-22 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 443 2.2E-17 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 PANTHER PTHR22573:SF15 1 448 2.2E-159 T 21-04-2016 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Gene3D G3DSA:3.30.310.50 369 445 7.2E-21 T 21-04-2016 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Gene3D G3DSA:3.40.120.10 3 151 4.5E-45 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 446 43.691 T 21-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 172 253 4.7E-13 T 21-04-2016 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 444 1.4E-190 T 21-04-2016 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Gene3D G3DSA:3.40.120.10 175 249 6.1E-20 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 95 104 - T 21-04-2016 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Gene3D G3DSA:3.40.120.10 250 367 3.2E-37 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 136 1.3E-41 T 21-04-2016 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 PANTHER PTHR22573 1 448 2.2E-159 T 21-04-2016 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 SUPERFAMILY SSF53738 257 365 1.49E-31 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 SUPERFAMILY SSF53738 2 164 3.18E-42 T 21-04-2016 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS03785 3e568bfc2ad3ffccb0d5c41cde05fedb 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 365 7.3E-32 T 21-04-2016 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 HSISS4_RS07760 46100452e256bd1a81d2ffb9d6b9f5d9 263 Gene3D G3DSA:3.90.1200.10 69 226 2.4E-16 T 21-04-2016 HSISS4_RS07760 46100452e256bd1a81d2ffb9d6b9f5d9 263 Pfam PF01636 Phosphotransferase enzyme family 40 212 7.1E-18 T 21-04-2016 IPR002575 Aminoglycoside phosphotransferase HSISS4_RS07760 46100452e256bd1a81d2ffb9d6b9f5d9 263 SUPERFAMILY SSF56112 8 226 1.48E-33 T 21-04-2016 IPR011009 Protein kinase-like domain HSISS4_RS07760 46100452e256bd1a81d2ffb9d6b9f5d9 263 PANTHER PTHR40086 5 262 1.6E-55 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 823 1024 1.65E-26 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 960 1025 2.3E-17 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 161 225 1.2E-11 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 426 473 1.6E-9 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 365 408 6.6E-7 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 561 612 1.1E-7 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 874 959 1.8E-11 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 150 338 6.77E-23 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 749 807 1.3E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 353 410 2.6E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 492 549 4.0E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 686 745 6.6E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 427 483 3.9E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 163 218 5.4E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 954 1014 1.5E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 626 684 9.2E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 563 625 3.9E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 224 279 2.5E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 617 664 2.3E-10 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 665 781 2.0E-16 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 279 534 1.68E-25 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 560 732 1.11E-33 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 488 528 1.11E-33 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 474 520 3.9E-5 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 226 305 1.7E-8 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 788 835 2.2E-5 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Gene3D G3DSA:2.10.270.10 306 364 9.0E-10 T 21-04-2016 HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Pfam PF01473 Putative cell wall binding repeat 617 634 3.8E-5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Pfam PF01473 Putative cell wall binding repeat 347 361 0.48 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Pfam PF01473 Putative cell wall binding repeat 743 757 0.35 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 Pfam PF01473 Putative cell wall binding repeat 945 960 0.1 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06590 3279faeaec6879f972f5c2f5dac7708d 1030 SUPERFAMILY SSF69360 742 834 9.22E-16 T 21-04-2016 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 PANTHER PTHR10314:SF4 77 130 4.8E-18 T 21-04-2016 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 PANTHER PTHR10314:SF4 11 54 4.8E-18 T 21-04-2016 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 15 258 29.434 T 21-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 Pfam PF00290 Tryptophan synthase alpha chain 10 252 2.2E-82 T 21-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 Gene3D G3DSA:3.20.20.70 5 249 5.4E-80 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 51 64 - T 21-04-2016 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 SUPERFAMILY SSF51366 5 253 9.42E-71 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 11 249 2.7E-60 T 21-04-2016 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20|UniPathway: UPA00035 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 PANTHER PTHR10314 77 130 4.8E-18 T 21-04-2016 HSISS4_RS07645 ed7c8a7fff6a1a9da4649bf2da62a711 260 PANTHER PTHR10314 11 54 4.8E-18 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 SMART SM00382 49 233 9.2E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 Gene3D G3DSA:3.40.50.300 3 256 5.0E-60 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220:SF333 37 263 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220:SF333 5 13 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220:SF333 290 322 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 SUPERFAMILY SSF52540 35 255 1.19E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220 37 263 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220 5 13 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 PANTHER PTHR24220 290 322 2.3E-89 T 21-04-2016 HSISS4_RS06065 9317c629753948969a22d7c9fc5efb76 330 Pfam PF00005 ABC transporter 41 184 3.7E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 Gene3D G3DSA:3.30.1330.30 3 91 7.8E-23 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 SMART SM00967 29 95 1.9E-15 T 21-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 29 93 5.6E-11 T 21-04-2016 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 Pfam PF00588 SpoU rRNA Methylase family 104 243 4.4E-37 T 21-04-2016 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 PANTHER PTHR12029 1 245 9.1E-64 T 21-04-2016 HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 SUPERFAMILY SSF75217 86 244 6.34E-42 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 SUPERFAMILY SSF55315 3 91 3.06E-19 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS01185 5b5501ffbe24daf3b88f711cb33b7696 245 Gene3D G3DSA:3.40.1280.10 104 245 1.4E-48 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS06060 1965c8837e1e3f1895e16e71fa925f67 272 Pfam PF06182 ABC-2 family transporter protein 38 271 1.4E-23 T 21-04-2016 IPR010390 Protein of unknown function DUF990 HSISS4_RS06060 1965c8837e1e3f1895e16e71fa925f67 272 PANTHER PTHR36832 1 272 7.3E-109 T 21-04-2016 HSISS4_RS06060 1965c8837e1e3f1895e16e71fa925f67 272 PANTHER PTHR36832:SF1 1 272 7.3E-109 T 21-04-2016 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PANTHER PTHR10353:SF35 3 476 1.5E-285 T 21-04-2016 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 Pfam PF00232 Glycosyl hydrolase family 1 3 473 3.6E-135 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 Gene3D G3DSA:3.20.20.80 3 474 1.4E-147 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 9 23 - T 21-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PANTHER PTHR10353 3 476 1.5E-285 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 438 450 3.5E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 302 316 3.5E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 368 376 3.5E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 413 430 3.5E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 PRINTS PR00131 Glycosyl hydrolase family 1 signature 392 403 3.5E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 368 376 - T 21-04-2016 IPR018120 Glycoside hydrolase family 1, active site HSISS4_RS04690 032a7759706d5897002feb610443c84a 478 SUPERFAMILY SSF51445 1 473 4.53E-160 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 Gene3D G3DSA:1.10.357.10 10 175 1.7E-22 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 Pfam PF14278 Transcriptional regulator C-terminal region 81 157 7.1E-7 T 21-04-2016 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.1E-6 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.1E-6 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 PANTHER PTHR30055 8 173 1.9E-18 T 21-04-2016 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 3.8E-9 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 SUPERFAMILY SSF46689 7 69 2.44E-15 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS01210 8e5a222f074fd7f488bbe48d97a42337 180 PANTHER PTHR30055:SF55 8 173 1.9E-18 T 21-04-2016 HSISS4_RS06040 0544c182b04b14a074c2329175c09254 170 Gene3D G3DSA:3.40.50.360 1 167 2.2E-39 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS06040 0544c182b04b14a074c2329175c09254 170 SUPERFAMILY SSF52218 1 170 2.72E-39 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS06040 0544c182b04b14a074c2329175c09254 170 PANTHER PTHR10204:SF42 1 170 2.6E-45 T 21-04-2016 HSISS4_RS06040 0544c182b04b14a074c2329175c09254 170 Pfam PF02525 Flavodoxin-like fold 1 168 3.3E-37 T 21-04-2016 IPR003680 Flavodoxin-like fold HSISS4_RS06040 0544c182b04b14a074c2329175c09254 170 PANTHER PTHR10204 1 170 2.6E-45 T 21-04-2016 HSISS4_RS03290 99d4b32e63d47efa427de7b8ed6ffafc 213 Gene3D G3DSA:3.40.50.1110 13 211 4.4E-35 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS03290 99d4b32e63d47efa427de7b8ed6ffafc 213 SUPERFAMILY SSF52266 8 211 2.17E-36 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS03290 99d4b32e63d47efa427de7b8ed6ffafc 213 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 48 200 4.3E-18 T 21-04-2016 IPR013830 SGNH hydrolase-type esterase domain HSISS4_RS03290 99d4b32e63d47efa427de7b8ed6ffafc 213 PANTHER PTHR30383 50 213 4.6E-13 T 21-04-2016 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 577 1.7E-232 T 21-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Gene3D G3DSA:3.30.930.10 134 279 1.2E-111 T 21-04-2016 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Gene3D G3DSA:3.30.930.10 409 578 1.2E-111 T 21-04-2016 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Gene3D G3DSA:2.40.50.140 2 108 1.1E-36 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 469 485 9.0E-24 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 9.0E-24 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 513 527 9.0E-24 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 9.0E-24 T 21-04-2016 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Gene3D G3DSA:3.30.1360.30 280 408 1.0E-48 T 21-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 SUPERFAMILY SSF55681 115 295 2.68E-105 T 21-04-2016 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 SUPERFAMILY SSF55681 419 577 2.68E-105 T 21-04-2016 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 552 4.2E-105 T 21-04-2016 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PANTHER PTHR22594:SF5 365 566 2.2E-245 T 21-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PANTHER PTHR22594:SF5 1 300 2.2E-245 T 21-04-2016 IPR004524 Aspartate-tRNA ligase, bacterial/mitochondrial-type GO:0005524|GO:0016874 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 SUPERFAMILY SSF50249 2 110 4.57E-29 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Pfam PF01336 OB-fold nucleic acid binding domain 20 103 9.5E-17 T 21-04-2016 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 SUPERFAMILY SSF55261 292 414 9.48E-37 T 21-04-2016 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Pfam PF02938 GAD domain 314 400 1.7E-24 T 21-04-2016 IPR029351 GAD domain HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PANTHER PTHR22594 365 566 2.2E-245 T 21-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 PANTHER PTHR22594 1 300 2.2E-245 T 21-04-2016 IPR018150 Aminoacyl-tRNA synthetase, class II (D/K/N)-like GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS09455 4cb15e25d361c3a6a1405f39fc899980 583 Hamap MF_00044 Aspartate--tRNA(Asp) ligase [aspS]. 2 558 35.144 T 21-04-2016 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 SUPERFAMILY SSF51569 1 293 1.21E-96 T 21-04-2016 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 Gene3D G3DSA:3.20.20.70 1 293 1.8E-102 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 293 1.2E-121 T 21-04-2016 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385|UniPathway: UPA00109 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 PIRSF PIRSF001359 1 293 3.3E-116 T 21-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 293 1.3E-92 T 21-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 133 144 - T 21-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 21-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 Pfam PF01116 Fructose-bisphosphate aldolase class-II 6 292 1.3E-94 T 21-04-2016 IPR000771 Ketose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 HSISS4_RS09205 6fcf067a382af7432313720f320d3be3 293 PANTHER PTHR30304 1 293 1.5E-90 T 21-04-2016 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 3.6E-10 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 3.6E-10 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 Gene3D G3DSA:1.10.10.10 3 64 2.2E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PANTHER PTHR11751 121 140 2.7E-31 T 21-04-2016 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PANTHER PTHR11751 1 74 2.7E-31 T 21-04-2016 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PANTHER PTHR11751:SF333 121 140 2.7E-31 T 21-04-2016 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 PANTHER PTHR11751:SF333 1 74 2.7E-31 T 21-04-2016 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 SUPERFAMILY SSF64288 55 230 9.89E-47 T 21-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HSISS4_RS05430 233955d540c836189d042ada823b929a 232 SMART SM00345 8 67 4.8E-23 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 SUPERFAMILY SSF46785 3 71 8.52E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05430 233955d540c836189d042ada823b929a 232 SMART SM00866 88 226 2.5E-36 T 21-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 Gene3D G3DSA:3.40.1410.10 65 231 4.9E-51 T 21-04-2016 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain HSISS4_RS05430 233955d540c836189d042ada823b929a 232 Pfam PF07702 UTRA domain 88 226 2.2E-36 T 21-04-2016 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 HSISS4_RS05430 233955d540c836189d042ada823b929a 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.7E-22 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 SUPERFAMILY SSF54565 2 86 1.16E-34 T 21-04-2016 IPR023803 Ribosomal protein S16 domain HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 Gene3D G3DSA:3.30.1320.10 2 84 4.2E-36 T 21-04-2016 IPR023803 Ribosomal protein S16 domain HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.598 T 21-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 Pfam PF00886 Ribosomal protein S16 9 67 3.7E-26 T 21-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 PANTHER PTHR12919 2 83 3.4E-44 T 21-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07400 3c365d47917f837c90ea835ceb2c7f66 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 80 1.1E-35 T 21-04-2016 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 Gene3D G3DSA:3.30.1360.60 1 79 2.5E-26 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 SUPERFAMILY SSF55604 6 79 3.53E-20 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 550 562 - T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 SUPERFAMILY SSF51261 483 630 1.83E-53 T 21-04-2016 IPR011055 Duplicated hybrid motif HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 Gene3D G3DSA:2.70.70.10 484 632 2.6E-60 T 21-04-2016 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 Pfam PF02378 Phosphotransferase system, EIIC 109 401 4.9E-31 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 PANTHER PTHR30175 1 583 1.5E-247 T 21-04-2016 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 488 608 7.9E-46 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 487 611 2.0E-50 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 PANTHER PTHR30175:SF7 1 583 1.5E-247 T 21-04-2016 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 Pfam PF00367 phosphotransferase system, EIIB 8 41 1.9E-15 T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS08355 fc462a1f6eacd8a43dd0ace56fd0491a 633 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 455 5.0E-174 T 21-04-2016 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 HSISS4_RS02935 f0d3cb4ef378247829f1652c68c030ac 78 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 76 6.9E-18 T 21-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HSISS4_RS02935 f0d3cb4ef378247829f1652c68c030ac 78 Pfam PF03840 Preprotein translocase SecG subunit 4 75 1.4E-14 T 21-04-2016 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.0E-25 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PRINTS PR00315 GTP-binding elongation factor signature 61 69 2.0E-25 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PRINTS PR00315 GTP-binding elongation factor signature 81 91 2.0E-25 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PRINTS PR00315 GTP-binding elongation factor signature 97 108 2.0E-25 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PRINTS PR00315 GTP-binding elongation factor signature 134 143 2.0E-25 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Gene3D G3DSA:2.40.30.10 305 396 9.4E-45 T 21-04-2016 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Gene3D G3DSA:2.40.30.10 212 302 3.6E-37 T 21-04-2016 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Pfam PF03144 Elongation factor Tu domain 2 228 297 8.2E-17 T 21-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 SUPERFAMILY SSF50465 306 397 4.32E-35 T 21-04-2016 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 SUPERFAMILY SSF50447 208 305 9.98E-29 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PANTHER PTHR23115 1 397 3.1E-243 T 21-04-2016 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 SUPERFAMILY SSF52540 6 222 3.27E-61 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 398 59.371 T 21-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 PANTHER PTHR23115:SF112 1 397 3.1E-243 T 21-04-2016 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 2.5E-13 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Gene3D G3DSA:3.40.50.300 3 211 2.8E-72 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Pfam PF00009 Elongation factor Tu GTP binding domain 10 204 7.5E-59 T 21-04-2016 HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 54 69 - T 21-04-2016 IPR031157 Tr-type G domain, conserved site HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 Pfam PF03143 Elongation factor Tu C-terminal domain 302 396 1.1E-31 T 21-04-2016 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal HSISS4_RS02285 d0cf35e47f0fbd7e16b4c13aff43c8a9 398 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 6.2E-222 T 21-04-2016 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 SMART SM00382 28 228 3.5E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 Pfam PF00005 ABC transporter 21 179 2.6E-31 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 PANTHER PTHR24220:SF358 5 110 1.5E-123 T 21-04-2016 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 PANTHER PTHR24220:SF358 126 254 1.5E-123 T 21-04-2016 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 SUPERFAMILY SSF52540 3 250 5.33E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 8.8E-13 T 21-04-2016 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 PANTHER PTHR24220 5 110 1.5E-123 T 21-04-2016 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 PANTHER PTHR24220 126 254 1.5E-123 T 21-04-2016 HSISS4_RS01650 2781ee035f0cc04a24edfcc27c5be408 254 Gene3D G3DSA:3.40.50.300 3 249 3.9E-72 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 SMART SM00849 12 194 1.3E-37 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 PANTHER PTHR11935 3 210 6.7E-56 T 21-04-2016 HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 Pfam PF00753 Metallo-beta-lactamase superfamily 11 194 1.1E-27 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 Gene3D G3DSA:3.60.15.10 1 210 2.2E-46 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 PANTHER PTHR11935:SF8 3 210 6.7E-56 T 21-04-2016 HSISS4_RS05610 584bee41e67105eb2d1aacb44ae0a6d7 211 SUPERFAMILY SSF56281 1 210 5.63E-46 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 Pfam PF13476 AAA domain 6 338 1.4E-10 T 21-04-2016 HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 PANTHER PTHR32114:SF2 2 1059 6.2E-78 T 21-04-2016 HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 Gene3D G3DSA:3.40.50.300 954 1045 4.9E-10 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 Gene3D G3DSA:3.40.50.300 1 167 1.1E-20 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 SUPERFAMILY SSF52540 20 228 9.35E-22 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 SUPERFAMILY SSF52540 951 1045 9.35E-22 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 PANTHER PTHR32114 2 1059 6.2E-78 T 21-04-2016 IPR027050 Nuclease SbcCD subunit C GO:0004518|GO:0006281 HSISS4_RS06770 d77f3328c21c21af5722e3865a7e1659 1059 Pfam PF13558 Putative exonuclease SbcCD, C subunit 939 1016 2.6E-12 T 21-04-2016 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.3E-34 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.3E-34 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.3E-34 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 114 136 1.3E-34 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 87 103 1.3E-34 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 160 32.638 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 SUPERFAMILY SSF52374 3 156 2.17E-40 T 21-04-2016 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 Pfam PF01467 Cytidylyltransferase-like 6 135 1.8E-17 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 64 1.6E-15 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 6.8E-58 T 21-04-2016 IPR001980 Coenzyme A biosynthesis protein GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|UniPathway: UPA00241 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 Gene3D G3DSA:3.40.50.620 1 160 1.2E-48 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PANTHER PTHR21342:SF1 1 165 7.1E-59 T 21-04-2016 HSISS4_RS07980 b3ffbc6beba610089c7c4b7635d857a9 165 PANTHER PTHR21342 1 165 7.1E-59 T 21-04-2016 HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 Pfam PF00583 Acetyltransferase (GNAT) family 52 106 2.8E-4 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 Pfam PF13673 Acetyltransferase (GNAT) domain 186 280 1.7E-14 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 Gene3D G3DSA:3.40.630.30 155 278 2.3E-25 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 PANTHER PTHR23091 122 280 2.5E-50 T 21-04-2016 HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 Gene3D G3DSA:3.40.630.30 6 109 7.4E-11 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 SUPERFAMILY SSF55729 118 279 7.6E-26 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 PANTHER PTHR23091:SF220 122 280 2.5E-50 T 21-04-2016 HSISS4_RS04410 bdff3668f27759adb2987fb5cd334db7 288 SUPERFAMILY SSF55729 8 108 7.62E-10 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PANTHER PTHR11575 117 712 5.7E-182 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 128 146 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 350 373 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 322 339 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 633 652 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 532 555 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PRINTS PR01607 Apyrase family signature 394 414 5.4E-24 T 21-04-2016 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 Pfam PF02872 5'-nucleotidase, C-terminal domain 462 652 1.6E-25 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 SUPERFAMILY SSF55816 462 695 1.01E-42 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 SUPERFAMILY SSF56300 126 459 1.9E-75 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS00770 483963260844466d4309549d54075ae1 846 Pfam PF00149 Calcineurin-like phosphoesterase 130 367 5.6E-10 T 21-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 812 845 8.4E-8 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS00770 483963260844466d4309549d54075ae1 846 PANTHER PTHR11575:SF6 117 712 5.7E-182 T 21-04-2016 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 Gene3D G3DSA:3.60.21.10 122 458 1.1E-82 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS00770 483963260844466d4309549d54075ae1 846 Gene3D G3DSA:3.90.780.10 462 695 1.0E-45 T 21-04-2016 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 HSISS4_RS00770 483963260844466d4309549d54075ae1 846 Pfam PF00746 Gram positive anchor 808 842 1.3E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS00770 483963260844466d4309549d54075ae1 846 ProSitePatterns PS00786 5'-nucleotidase signature 2. 216 227 - T 21-04-2016 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 HSISS4_RS04040 b470297ddf4229e0112be5476b2e3cb7 232 Gene3D G3DSA:1.10.10.630 126 200 2.9E-23 T 21-04-2016 IPR006343 Replication protein, DnaD/DnaB domain HSISS4_RS04040 b470297ddf4229e0112be5476b2e3cb7 232 SUPERFAMILY SSF158499 133 194 1.31E-15 T 21-04-2016 IPR006343 Replication protein, DnaD/DnaB domain HSISS4_RS04040 b470297ddf4229e0112be5476b2e3cb7 232 PANTHER PTHR41274 1 229 4.1E-36 T 21-04-2016 HSISS4_RS04040 b470297ddf4229e0112be5476b2e3cb7 232 Pfam PF07261 Replication initiation and membrane attachment 132 201 9.2E-18 T 21-04-2016 IPR006343 Replication protein, DnaD/DnaB domain HSISS4_RS04040 b470297ddf4229e0112be5476b2e3cb7 232 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 131 200 1.2E-19 T 21-04-2016 IPR006343 Replication protein, DnaD/DnaB domain HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 PANTHER PTHR19278 3 203 6.3E-64 T 21-04-2016 HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 Pfam PF00156 Phosphoribosyl transferase domain 51 188 5.4E-18 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 SUPERFAMILY SSF53271 11 208 1.21E-52 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 Gene3D G3DSA:3.40.50.2020 3 208 3.3E-59 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 209 31.091 T 21-04-2016 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS05000 6709e295b80158f0940da1834704514d 209 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 178 7.8E-47 T 21-04-2016 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS07130 15754da82417c6af4144e7aa7c317788 308 PANTHER PTHR10859:SF81 1 307 2.0E-141 T 21-04-2016 HSISS4_RS07130 15754da82417c6af4144e7aa7c317788 308 Pfam PF00535 Glycosyl transferase family 2 6 144 5.1E-33 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS07130 15754da82417c6af4144e7aa7c317788 308 Gene3D G3DSA:3.90.550.10 2 142 5.4E-28 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07130 15754da82417c6af4144e7aa7c317788 308 SUPERFAMILY SSF53448 1 251 4.96E-41 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07130 15754da82417c6af4144e7aa7c317788 308 PANTHER PTHR10859 1 307 2.0E-141 T 21-04-2016 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 SMART SM01002 148 297 1.0E-81 T 21-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 Gene3D G3DSA:3.40.50.1770 200 358 1.7E-29 T 21-04-2016 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 SUPERFAMILY SSF51735 136 303 1.94E-47 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 21-04-2016 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 Gene3D G3DSA:3.50.50.60 178 199 1.2E-4 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 2.4E-45 T 21-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 SMART SM01003 4 136 8.2E-74 T 21-04-2016 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 1.0E-82 T 21-04-2016 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 PIRSF PIRSF000183 1 370 4.0E-179 T 21-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 PANTHER PTHR10160 1 370 9.1E-196 T 21-04-2016 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 SUPERFAMILY SSF52283 305 360 3.15E-64 T 21-04-2016 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 SUPERFAMILY SSF52283 1 136 3.15E-64 T 21-04-2016 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 366 1.5E-168 T 21-04-2016 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|UniPathway: UPA00527 HSISS4_RS02565 6d676def9bd9147a7926d60a399aa684 370 Gene3D G3DSA:3.40.50.1770 3 177 6.5E-62 T 21-04-2016 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 192 1.4E-48 T 21-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 201 5.4E-48 T 21-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 SUPERFAMILY SSF53335 1 237 2.94E-45 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 PANTHER PTHR31760:SF0 8 237 2.1E-83 T 21-04-2016 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 Gene3D G3DSA:3.40.50.150 3 237 9.4E-78 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 PIRSF PIRSF003078 1 220 8.9E-52 T 21-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 215 27.775 T 21-04-2016 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 HSISS4_RS01420 adfcd7e57110a4ab394b7b5f3b7b754a 237 PANTHER PTHR31760 8 237 2.1E-83 T 21-04-2016 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 Pfam PF00258 Flavodoxin 6 132 2.2E-23 T 21-04-2016 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 SUPERFAMILY SSF52218 5 146 1.3E-39 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 PANTHER PTHR19384 1 146 3.9E-50 T 21-04-2016 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 21-04-2016 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 PANTHER PTHR19384:SF81 1 146 3.9E-50 T 21-04-2016 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 PRINTS PR00369 Flavodoxin signature 5 18 1.7E-5 T 21-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 PRINTS PR00369 Flavodoxin signature 82 92 1.7E-5 T 21-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 PRINTS PR00369 Flavodoxin signature 53 64 1.7E-5 T 21-04-2016 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 Gene3D G3DSA:3.40.50.360 6 146 7.1E-42 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS04205 0fe5c0c96a2a279800caaf4339025f29 147 TIGRFAM TIGR01753 flav_short: flavodoxin 5 142 2.2E-45 T 21-04-2016 IPR010087 Flavodoxin, short chain GO:0010181 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 Gene3D G3DSA:3.40.50.1000 89 233 1.1E-36 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 PANTHER PTHR12725 2 267 5.7E-42 T 21-04-2016 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 202 1.1E-25 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 PANTHER PTHR12725:SF78 2 267 5.7E-42 T 21-04-2016 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 SUPERFAMILY SSF56784 1 232 1.49E-43 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.6E-7 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 113 126 4.6E-7 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 4.6E-7 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS03425 f0ebbe8c64e6c75c40178fd6e2dda6c1 300 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 106 197 1.6E-15 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SMART SM00896 709 802 5.3E-40 T 21-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.30.70.380 711 802 9.1E-30 T 21-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SMART SM00874 409 477 5.7E-25 T 21-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 802 4.4E-256 T 21-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SUPERFAMILY SSF50249 36 197 6.57E-43 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SUPERFAMILY SSF56037 210 401 1.78E-68 T 21-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.30.56.10 1 38 4.6E-25 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.30.56.10 161 190 4.6E-25 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SMART SM00873 219 392 6.6E-86 T 21-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.30.56.20 408 481 6.8E-23 T 21-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.50.40.10 207 400 4.3E-79 T 21-04-2016 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Pfam PF03483 B3/4 domain 222 391 2.9E-66 T 21-04-2016 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Pfam PF03484 tRNA synthetase B5 domain 412 477 9.2E-16 T 21-04-2016 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Pfam PF01588 Putative tRNA binding domain 45 148 1.6E-17 T 21-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:3.30.930.10 494 695 8.2E-65 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 PANTHER PTHR10947:SF0 2 802 3.4E-294 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 PANTHER PTHR10947 2 802 3.4E-294 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SUPERFAMILY SSF55681 473 694 4.52E-49 T 21-04-2016 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SUPERFAMILY SSF54991 705 802 8.63E-30 T 21-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 796 46.111 T 21-04-2016 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 SUPERFAMILY SSF46955 409 481 1.28E-17 T 21-04-2016 IPR009061 Putative DNA-binding domain HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 802 7.4E-28 T 21-04-2016 IPR005121 Phenylalanine-tRNA ligase, beta subunit, ferrodoxin-fold anticodon-binding GO:0000049|GO:0000287|GO:0004826|GO:0005524|GO:0006432|GO:0008033 KEGG: 00970+6.1.1.20 HSISS4_RS05910 3463bedc823e808013a777ae72ec8b52 802 Gene3D G3DSA:2.40.50.140 41 160 1.8E-41 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08900 b7f64c6dc423b9ead78dba09268fa86c 186 TIGRFAM TIGR02185 Trep_Strep: putative ECF transporter S component, Trep_Strep family 10 186 1.5E-28 T 21-04-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane HSISS4_RS08900 b7f64c6dc423b9ead78dba09268fa86c 186 Pfam PF09605 Hypothetical bacterial integral membrane protein (Trep_Strep) 13 186 4.4E-40 T 21-04-2016 IPR011733 Conserved hypothetical CHP02185, integral membrane HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 Pfam PF01544 CorA-like Mg2+ transporter protein 13 296 1.7E-50 T 21-04-2016 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 SUPERFAMILY SSF143865 11 236 3.79E-29 T 21-04-2016 HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 SUPERFAMILY SSF144083 237 297 1.44E-10 T 21-04-2016 HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 PANTHER PTHR21535:SF40 1 296 4.2E-46 T 21-04-2016 HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 Gene3D G3DSA:1.20.58.340 229 297 6.3E-13 T 21-04-2016 HSISS4_RS07545 f2f686838f23b34df5944230e5049619 301 PANTHER PTHR21535 1 296 4.2E-46 T 21-04-2016 HSISS4_RS00180 6d4db0ab875eb3800e45c693c01fe1f1 174 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 24 159 4.5E-15 T 21-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HSISS4_RS00180 6d4db0ab875eb3800e45c693c01fe1f1 174 Pfam PF04093 rod shape-determining protein MreD 7 165 3.7E-15 T 21-04-2016 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 PANTHER PTHR10916 1 66 2.0E-21 T 21-04-2016 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 PANTHER PTHR10916:SF0 1 66 2.0E-21 T 21-04-2016 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 12 66 1.4E-24 T 21-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 SUPERFAMILY SSF46561 11 66 1.57E-19 T 21-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 Pfam PF00831 Ribosomal L29 protein 11 66 6.2E-23 T 21-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 7 67 16.657 T 21-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 Gene3D G3DSA:1.10.287.310 10 66 1.8E-24 T 21-04-2016 IPR001854 Ribosomal protein L29 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09310 706249c9b80375b9847c2eae6637fb2f 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 46 60 - T 21-04-2016 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 4 236 15.992 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 Pfam PF00902 Sec-independent protein translocase protein (TatC) 12 216 2.0E-50 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PANTHER PTHR30371 1 238 6.0E-83 T 21-04-2016 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PANTHER PTHR30371:SF4 1 238 6.0E-83 T 21-04-2016 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 10 221 1.7E-51 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 80 98 9.4E-31 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 9 36 9.4E-31 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 149 177 9.4E-31 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS04800 468a4f615194f13034ed084966e21e54 242 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 98 124 9.4E-31 T 21-04-2016 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 PANTHER PTHR21599 1 371 2.0E-126 T 21-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 PANTHER PTHR21599:SF0 1 371 2.0E-126 T 21-04-2016 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 Gene3D G3DSA:3.90.1510.10 43 268 2.3E-73 T 21-04-2016 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 367 7.2E-129 T 21-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 Pfam PF02595 Glycerate kinase family 3 365 6.4E-121 T 21-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 SUPERFAMILY SSF110738 1 367 4.18E-119 T 21-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HSISS4_RS02975 a67cf67263904bbb48678b0ec733bbc2 371 PIRSF PIRSF006078 1 370 3.5E-115 T 21-04-2016 IPR004381 Glycerate kinase GO:0008887|GO:0031388 HSISS4_RS03505 c8ec56d619144555f2e354454ce6aede 97 SUPERFAMILY SSF47413 25 91 1.24E-14 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS03505 c8ec56d619144555f2e354454ce6aede 97 Gene3D G3DSA:1.10.260.40 25 90 3.5E-15 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS03505 c8ec56d619144555f2e354454ce6aede 97 SMART SM00530 35 90 2.1E-12 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS03505 c8ec56d619144555f2e354454ce6aede 97 Pfam PF01381 Helix-turn-helix 37 88 7.5E-13 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06160 92d87385960c1700356d99d01f4e8c5d 422 TIGRFAM TIGR03173 pbuX: xanthine permease 13 416 2.0E-149 T 21-04-2016 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 HSISS4_RS06160 92d87385960c1700356d99d01f4e8c5d 422 Pfam PF00860 Permease family 9 380 1.7E-99 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS06160 92d87385960c1700356d99d01f4e8c5d 422 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 331 351 - T 21-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HSISS4_RS06160 92d87385960c1700356d99d01f4e8c5d 422 PANTHER PTHR11119 9 421 1.1E-109 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS06160 92d87385960c1700356d99d01f4e8c5d 422 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 8 414 3.6E-116 T 21-04-2016 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 HSISS4_RS07430 a7556a815e9e3d139c49183a468afbf6 250 Pfam PF15983 Domain of unknown function (DUF4767) 129 248 2.8E-17 T 21-04-2016 IPR031927 Domain of unknown function DUF4767 HSISS4_RS01380 bced3875327f2f04ba3463a3ac2e6676 230 PANTHER PTHR30450 26 230 2.7E-73 T 21-04-2016 HSISS4_RS01380 bced3875327f2f04ba3463a3ac2e6676 230 PANTHER PTHR30450:SF1 26 230 2.7E-73 T 21-04-2016 HSISS4_RS01380 bced3875327f2f04ba3463a3ac2e6676 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 228 1.2E-14 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS01380 bced3875327f2f04ba3463a3ac2e6676 230 Gene3D G3DSA:1.10.3720.10 25 228 1.7E-29 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS01380 bced3875327f2f04ba3463a3ac2e6676 230 SUPERFAMILY SSF161098 24 217 1.09E-32 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 407 164.972 T 21-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 372 1.3E-62 T 21-04-2016 IPR020536 Thil, AANH domain GO:0004810 UniPathway: UPA00060 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 Pfam PF02926 THUMP domain 50 166 5.6E-14 T 21-04-2016 IPR004114 THUMP domain GO:0003723 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 SUPERFAMILY SSF143437 5 175 1.44E-52 T 21-04-2016 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 Gene3D G3DSA:3.40.50.620 175 335 3.8E-50 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 SMART SM00981 76 167 7.0E-18 T 21-04-2016 IPR004114 THUMP domain GO:0003723 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 SUPERFAMILY SSF52402 176 389 3.97E-50 T 21-04-2016 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 8 377 4.6E-119 T 21-04-2016 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 UniPathway: UPA00060 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 PANTHER PTHR14911:SF16 4 398 1.3E-175 T 21-04-2016 HSISS4_RS01890 f004b114a7912ab7a708af7ea2a56a1f 407 PANTHER PTHR14911 4 398 1.3E-175 T 21-04-2016 HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 PANTHER PTHR24220:SF453 5 200 8.6E-63 T 21-04-2016 HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 SMART SM00382 28 196 2.9E-5 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 Gene3D G3DSA:3.40.50.300 2 208 3.0E-50 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 PANTHER PTHR24220 5 200 8.6E-63 T 21-04-2016 HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 Pfam PF00005 ABC transporter 19 148 2.2E-22 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08400 4dabd6230ed3d1aebe9deffe7bade00b 273 SUPERFAMILY SSF52540 3 208 1.95E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 Pfam PF00480 ROK family 5 289 7.9E-78 T 21-04-2016 IPR000600 ROK family HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 Gene3D G3DSA:3.30.420.40 2 107 1.2E-37 T 21-04-2016 HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 ProSitePatterns PS01125 ROK family signature. 131 156 - T 21-04-2016 IPR000600 ROK family HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 Gene3D G3DSA:3.30.420.40 108 293 4.7E-62 T 21-04-2016 HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 PANTHER PTHR18964 1 291 8.7E-81 T 21-04-2016 HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 SUPERFAMILY SSF53067 5 292 4.84E-43 T 21-04-2016 HSISS4_RS08350 dd13612f5efdd8742954a613db011b80 297 PANTHER PTHR18964:SF10 1 291 8.7E-81 T 21-04-2016 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 Hamap MF_01582 Serine/threonine transporter SstT [sstT]. 1 402 35.394 T 21-04-2016 IPR023025 Serine/threonine transporter SstT GO:0015293|GO:0015826|GO:0032329 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PANTHER PTHR11958:SF68 10 395 4.0E-192 T 21-04-2016 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PANTHER PTHR11958 10 395 4.0E-192 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 SUPERFAMILY SSF118215 13 396 3.27E-94 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 Pfam PF00375 Sodium:dicarboxylate symporter family 13 396 2.1E-66 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PRINTS PR00173 Glutamate-aspartate symporter signature 285 311 4.0E-14 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PRINTS PR00173 Glutamate-aspartate symporter signature 320 339 4.0E-14 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 4.0E-14 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PRINTS PR00173 Glutamate-aspartate symporter signature 218 237 4.0E-14 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 PRINTS PR00173 Glutamate-aspartate symporter signature 183 202 4.0E-14 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS01385 7c49e4e8ef7a7f465eac2c810db5643c 402 Gene3D G3DSA:1.10.3860.10 5 399 2.6E-86 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 Gene3D G3DSA:2.40.30.60 4 91 6.1E-14 T 21-04-2016 IPR002676 RimM protein GO:0006364 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 PANTHER PTHR33692 3 172 1.9E-57 T 21-04-2016 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 4 168 7.7E-50 T 21-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 PANTHER PTHR33692:SF1 3 172 1.9E-57 T 21-04-2016 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 Gene3D G3DSA:2.30.30.240 99 168 3.0E-23 T 21-04-2016 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 SUPERFAMILY SSF50447 3 91 3.28E-19 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 Pfam PF01782 RimM N-terminal domain 6 89 3.7E-21 T 21-04-2016 IPR002676 RimM protein GO:0006364 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 3 168 23.474 T 21-04-2016 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 Pfam PF05239 PRC-barrel domain 97 167 1.6E-11 T 21-04-2016 IPR027275 PRC-barrel domain HSISS4_RS06880 ad8f743752d644513155ee3098fe4462 172 SUPERFAMILY SSF50346 99 168 1.81E-18 T 21-04-2016 IPR011033 PRC-barrel-like HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Gene3D G3DSA:3.40.50.300 139 284 1.7E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Gene3D G3DSA:3.40.50.300 328 558 8.7E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Gene3D G3DSA:3.40.50.300 9 102 1.7E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 SUPERFAMILY SSF52540 11 235 9.16E-43 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 SMART SM00382 351 533 5.8E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 SMART SM00382 28 243 2.0E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 ProSitePatterns PS00211 ABC transporters family signature. 444 458 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 SUPERFAMILY SSF52540 309 534 2.92E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Pfam PF00005 ABC transporter 20 191 8.0E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Pfam PF00005 ABC transporter 344 472 5.3E-19 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 PANTHER PTHR19211:SF64 1 582 0.0 T 21-04-2016 HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 PANTHER PTHR19211 1 582 0.0 T 21-04-2016 HSISS4_RS03745 e042c8b236d87cc0eebe329c940dfa3f 639 Pfam PF12848 ABC transporter 231 310 1.8E-25 T 21-04-2016 IPR032781 ABC-transporter extension domain HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 Gene3D G3DSA:3.30.70.270 197 342 5.7E-35 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 SUPERFAMILY SSF55073 200 341 4.79E-31 T 21-04-2016 IPR029787 Nucleotide cyclase HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 PANTHER PTHR10799 15 93 5.0E-13 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 PANTHER PTHR10799 225 339 5.0E-13 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 Pfam PF08448 PAS fold 83 185 5.2E-11 T 21-04-2016 IPR013656 PAS fold-4 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 SUPERFAMILY SSF55785 83 185 1.69E-7 T 21-04-2016 IPR000014 PAS domain HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 Gene3D G3DSA:3.30.450.20 83 185 1.5E-8 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 191 340 1.4E-32 T 21-04-2016 IPR000160 GGDEF domain HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 PANTHER PTHR10799:SF750 15 93 5.0E-13 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 PANTHER PTHR10799:SF750 225 339 5.0E-13 T 21-04-2016 HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 SMART SM00267 184 345 3.6E-32 T 21-04-2016 IPR000160 GGDEF domain HSISS4_RS09515 1e89c0aec8b5a0bb13017313eae8cc34 345 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 341 9.9E-33 T 21-04-2016 IPR000160 GGDEF domain HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 191 207 - T 21-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 Pfam PF01026 TatD related DNase 5 254 4.9E-76 T 21-04-2016 IPR001130 TatD family GO:0016788 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 SUPERFAMILY SSF51556 2 257 3.41E-87 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 4 12 - T 21-04-2016 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 PIRSF PIRSF005902 1 258 2.0E-80 T 21-04-2016 IPR001130 TatD family GO:0016788 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 PANTHER PTHR10060:SF20 1 258 3.2E-119 T 21-04-2016 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 PANTHER PTHR10060 1 258 3.2E-119 T 21-04-2016 IPR001130 TatD family GO:0016788 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 Gene3D G3DSA:3.20.20.140 2 257 1.5E-89 T 21-04-2016 HSISS4_RS08645 c769505b7ae7c92feae5c8a326f89929 258 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 4 255 1.8E-78 T 21-04-2016 IPR015991 Uncharacterised deoxyribonuclease TatD-type GO:0004536 HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 Pfam PF00276 Ribosomal protein L23 5 88 1.4E-28 T 21-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 21-04-2016 IPR001014 Ribosomal protein L23/L25, conserved site HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 PANTHER PTHR11620 1 93 3.7E-29 T 21-04-2016 HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 Gene3D G3DSA:3.30.70.330 1 93 9.6E-32 T 21-04-2016 IPR012677 Nucleotide-binding alpha-beta plait domain GO:0000166 HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 95 21.469 T 21-04-2016 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09340 2e296a002ad8bde41c628b12a52f6b22 98 SUPERFAMILY SSF54189 1 91 2.01E-28 T 21-04-2016 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 PANTHER PTHR11835 2 345 1.8E-191 T 21-04-2016 IPR001804 Isocitrate and isopropylmalate dehydrogenases family GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 4 343 7.7E-142 T 21-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 SUPERFAMILY SSF53659 4 345 6.72E-119 T 21-04-2016 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 3 345 46.261 T 21-04-2016 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396|UniPathway: UPA00048 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 PANTHER PTHR11835:SF35 2 345 1.8E-191 T 21-04-2016 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 SMART SM01329 4 341 1.8E-188 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 341 3.3E-129 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 Gene3D G3DSA:3.40.718.10 1 345 1.2E-128 T 21-04-2016 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 HSISS4_RS04125 3d06e248913357d93a965e6d3ad499d7 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 236 255 - T 21-04-2016 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: REACT_1046 HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 36.009 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 172 2.5E-45 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 SUPERFAMILY SSF50249 1 172 2.23E-54 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 PANTHER PTHR10302 1 172 1.5E-48 T 21-04-2016 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 Gene3D G3DSA:2.40.50.140 1 117 8.8E-49 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 Gene3D G3DSA:2.40.50.140 152 172 8.8E-49 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08445 232c7d4e440701089f0d4bfb2e0920de 172 Pfam PF00436 Single-strand binding protein family 2 103 6.7E-36 T 21-04-2016 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 Pfam PF02780 Transketolase, C-terminal domain 208 330 3.5E-40 T 21-04-2016 IPR033248 Transketolase, C-terminal domain HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 SMART SM00861 5 194 6.1E-55 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 SUPERFAMILY SSF52922 203 338 6.54E-41 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 Gene3D G3DSA:3.40.50.970 4 208 3.0E-76 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 Gene3D G3DSA:3.40.50.920 209 338 6.1E-44 T 21-04-2016 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 Pfam PF02779 Transketolase, pyrimidine binding domain 9 193 9.5E-46 T 21-04-2016 IPR005475 Transketolase-like, pyrimidine-binding domain HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 PANTHER PTHR11624 2 340 2.3E-143 T 21-04-2016 IPR033247 Transketolase family HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 PANTHER PTHR11624:SF77 2 340 2.3E-143 T 21-04-2016 HSISS4_RS03235 3b0ffdbc1dc6669d83d5ef6cae949ea7 343 SUPERFAMILY SSF52518 7 218 4.02E-61 T 21-04-2016 IPR029061 Thiamin diphosphate-binding fold HSISS4_RS05280 a090eb8542969b1358746585b38cd4c8 284 SUPERFAMILY SSF51735 2 236 5.51E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS05280 a090eb8542969b1358746585b38cd4c8 284 Pfam PF05368 NmrA-like family 2 215 6.4E-22 T 21-04-2016 IPR008030 NmrA-like domain HSISS4_RS05280 a090eb8542969b1358746585b38cd4c8 284 PANTHER PTHR14194:SF73 2 274 5.6E-54 T 21-04-2016 HSISS4_RS05280 a090eb8542969b1358746585b38cd4c8 284 PANTHER PTHR14194 2 274 5.6E-54 T 21-04-2016 HSISS4_RS05280 a090eb8542969b1358746585b38cd4c8 284 Gene3D G3DSA:3.40.50.720 2 210 1.6E-29 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01060 96674b713e39f3296d1d59937cd56bd3 280 Pfam PF01061 ABC-2 type transporter 2 216 9.3E-12 T 21-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 Pfam PF00512 His Kinase A (phospho-acceptor) domain 274 333 2.3E-15 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SUPERFAMILY SSF47384 256 337 1.65E-19 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SUPERFAMILY SSF55874 329 497 4.58E-37 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 Gene3D G3DSA:1.10.287.130 263 324 8.2E-18 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SMART SM00387 385 499 7.7E-28 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 387 497 7.2E-23 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 477 3.4E-15 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 436 3.4E-15 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 450 3.4E-15 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PRINTS PR00344 Bacterial sensor protein C-terminal signature 483 496 3.4E-15 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SMART SM00304 218 272 1.4E-8 T 21-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SUPERFAMILY SSF158472 219 269 1.57E-7 T 21-04-2016 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 Gene3D G3DSA:3.30.565.10 325 499 2.0E-39 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 SMART SM00388 273 340 2.1E-15 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 Pfam PF00672 HAMP domain 204 269 2.4E-11 T 21-04-2016 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PANTHER PTHR24423 179 196 7.4E-66 T 21-04-2016 HSISS4_RS01435 2363427ffe21dab71c7065e63cbb9c11 509 PANTHER PTHR24423 212 502 7.4E-66 T 21-04-2016 HSISS4_RS02280 de89ad948bcee667dbe383a8c1b74007 426 PANTHER PTHR30474 1 410 8.0E-128 T 21-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HSISS4_RS02280 de89ad948bcee667dbe383a8c1b74007 426 Pfam PF01098 Cell cycle protein 13 394 4.7E-90 T 21-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HSISS4_RS02280 de89ad948bcee667dbe383a8c1b74007 426 PANTHER PTHR30474:SF2 1 410 8.0E-128 T 21-04-2016 HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 PANTHER PTHR34697 4 832 6.0E-183 T 21-04-2016 HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 531 816 7.3E-82 T 21-04-2016 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 PANTHER PTHR34697:SF2 4 832 6.0E-183 T 21-04-2016 HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 SUPERFAMILY SSF55729 632 817 9.0E-14 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 Gene3D G3DSA:2.20.140.10 596 652 4.2E-4 T 21-04-2016 IPR008893 WGR domain HSISS4_RS06615 4839a8099163ea40bb3ffded4ab8796a 841 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 184 291 1.8E-12 T 21-04-2016 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD HSISS4_RS00455 7214470fa609bfbd7f98797b523b65c2 181 Gene3D G3DSA:3.40.50.360 1 180 4.1E-41 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS00455 7214470fa609bfbd7f98797b523b65c2 181 Pfam PF03358 NADPH-dependent FMN reductase 3 143 4.0E-26 T 21-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HSISS4_RS00455 7214470fa609bfbd7f98797b523b65c2 181 PANTHER PTHR30543 1 181 2.2E-45 T 21-04-2016 HSISS4_RS00455 7214470fa609bfbd7f98797b523b65c2 181 PANTHER PTHR30543:SF6 1 181 2.2E-45 T 21-04-2016 HSISS4_RS00455 7214470fa609bfbd7f98797b523b65c2 181 SUPERFAMILY SSF52218 2 177 2.79E-35 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 SUPERFAMILY SSF81338 13 287 7.98E-60 T 21-04-2016 IPR023271 Aquaporin-like HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 Pfam PF00230 Major intrinsic protein 12 279 7.0E-35 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 215 237 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 94 113 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 266 286 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 160 178 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 15 34 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PRINTS PR00783 Major intrinsic protein family signature 57 81 2.4E-39 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PANTHER PTHR19139 194 286 9.3E-60 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PANTHER PTHR19139 14 178 9.3E-60 T 21-04-2016 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PANTHER PTHR19139:SF147 194 286 9.3E-60 T 21-04-2016 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 PANTHER PTHR19139:SF147 14 178 9.3E-60 T 21-04-2016 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 ProSitePatterns PS00221 MIP family signature. 75 83 - T 21-04-2016 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08065 bbd28fdab224c40009acdc7b81f1bfe5 288 Gene3D G3DSA:1.20.1080.10 11 287 8.9E-75 T 21-04-2016 IPR023271 Aquaporin-like HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 Pfam PF02153 Prephenate dehydrogenase 18 276 2.8E-70 T 21-04-2016 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 Gene3D G3DSA:3.40.50.720 1 183 7.1E-38 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 Gene3D G3DSA:1.10.3660.10 225 282 4.9E-4 T 21-04-2016 HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 PANTHER PTHR21363 2 363 9.5E-74 T 21-04-2016 HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 SUPERFAMILY SSF51735 6 173 2.44E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 PANTHER PTHR21363:SF0 2 363 9.5E-74 T 21-04-2016 HSISS4_RS03025 822ac1c433e326c74c2c16de4227e3a2 368 SUPERFAMILY SSF48179 177 286 1.03E-31 T 21-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Pfam PF00005 ABC transporter 624 860 1.9E-11 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 ProSitePatterns PS00211 ABC transporters family signature. 830 844 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 ProSitePatterns PS00211 ABC transporters family signature. 489 503 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 925 0.0 T 21-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:1.10.8.280 284 405 3.7E-43 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 PANTHER PTHR32282 1 940 0.0 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.30.1490.20 132 154 4.8E-30 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.30.1490.20 201 248 4.8E-30 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 PANTHER PTHR32282:SF2 1 940 0.0 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:1.20.1580.10 406 479 6.9E-49 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:1.20.1580.10 92 130 6.9E-49 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:1.20.1580.10 249 282 6.9E-49 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:1.20.1580.10 694 820 7.7E-57 T 21-04-2016 HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 SUPERFAMILY SSF52540 10 205 1.2E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 SUPERFAMILY SSF52540 432 571 1.2E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.40.50.300 821 939 5.3E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.40.50.300 613 669 5.3E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.40.50.300 4 90 3.1E-55 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Gene3D G3DSA:3.40.50.300 480 598 3.1E-55 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 SUPERFAMILY SSF52540 616 914 3.7E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08420 66ee23079757184f79e296005916e8f1 941 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 940 22.781 T 21-04-2016 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 HSISS4_RS04095 73bc9cb53272c1869b0b40e285756dbd 190 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 4 186 1.2E-53 T 21-04-2016 IPR018672 Protein of unknown function DUF2140 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 318 1.7E-98 T 21-04-2016 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 Gene3D G3DSA:3.30.420.40 145 302 2.4E-58 T 21-04-2016 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 Gene3D G3DSA:3.30.420.40 3 144 3.3E-42 T 21-04-2016 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 SUPERFAMILY SSF53067 4 319 1.12E-68 T 21-04-2016 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 PANTHER PTHR18964:SF123 1 318 4.4E-99 T 21-04-2016 HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 Pfam PF00480 ROK family 6 318 4.7E-74 T 21-04-2016 IPR000600 ROK family HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 ProSitePatterns PS01125 ROK family signature. 139 166 - T 21-04-2016 IPR000600 ROK family HSISS4_RS03605 c718f110a2c1df00ebab38a2f0645158 322 PANTHER PTHR18964 1 318 4.4E-99 T 21-04-2016 HSISS4_RS04220 04b05e4aaafde9826b1b64cb6d44fc29 408 Gene3D G3DSA:1.10.3080.10 21 402 6.9E-40 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS04220 04b05e4aaafde9826b1b64cb6d44fc29 408 PRINTS PR00762 Chloride channel signature 154 173 2.5E-5 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04220 04b05e4aaafde9826b1b64cb6d44fc29 408 PRINTS PR00762 Chloride channel signature 317 337 2.5E-5 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04220 04b05e4aaafde9826b1b64cb6d44fc29 408 SUPERFAMILY SSF81340 12 405 2.09E-72 T 21-04-2016 IPR014743 Chloride channel, core GO:0005216|GO:0055085 HSISS4_RS04220 04b05e4aaafde9826b1b64cb6d44fc29 408 Pfam PF00654 Voltage gated chloride channel 63 391 4.9E-57 T 21-04-2016 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 Gene3D G3DSA:2.30.40.10 1 68 1.6E-25 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 Gene3D G3DSA:3.20.20.140 69 419 9.0E-95 T 21-04-2016 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 21-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 SUPERFAMILY SSF51556 54 365 1.53E-91 T 21-04-2016 IPR032466 Metal-dependent hydrolase HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 Pfam PF01979 Amidohydrolase family 50 419 6.7E-32 T 21-04-2016 IPR006680 Amidohydrolase-related GO:0016787 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 PANTHER PTHR11647:SF70 1 421 4.6E-165 T 21-04-2016 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 PANTHER PTHR11647 1 421 4.6E-165 T 21-04-2016 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 ProSitePatterns PS00482 Dihydroorotase signature 1. 57 65 - T 21-04-2016 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 SUPERFAMILY SSF51338 2 53 2.72E-24 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 SUPERFAMILY SSF51338 366 421 2.72E-24 T 21-04-2016 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 422 37.725 T 21-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS04730 20e0f3a913104dfaad6f9612261f8f36 422 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 421 2.1E-109 T 21-04-2016 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 SUPERFAMILY SSF111331 3 300 1.57E-73 T 21-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 Pfam PF00781 Diacylglycerol kinase catalytic domain 6 130 9.7E-34 T 21-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 297 1.0E-74 T 21-04-2016 IPR005218 Diacylglycerol/lipid kinase HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 Gene3D G3DSA:3.40.50.10330 21 96 6.7E-6 T 21-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 PANTHER PTHR12358:SF41 3 310 9.7E-125 T 21-04-2016 HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 SMART SM00046 5 136 4.1E-5 T 21-04-2016 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 HSISS4_RS07470 50ad09cfa071d1578e5eab59954cd5ab 337 PANTHER PTHR12358 3 310 9.7E-125 T 21-04-2016 HSISS4_RS07575 ac5f6fd41e0d9f36a093a703da911c6a 219 Pfam PF09529 Integral membrane protein (intg_mem_TP0381) 21 209 5.3E-32 T 21-04-2016 IPR011737 Conserved hypothetical protein CHP02206, TP0381 HSISS4_RS07575 ac5f6fd41e0d9f36a093a703da911c6a 219 TIGRFAM TIGR02206 intg_mem_TP0381: conserved hypothetical integral membrane protein TIGR02206 20 204 3.6E-22 T 21-04-2016 IPR011737 Conserved hypothetical protein CHP02206, TP0381 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PANTHER PTHR22912 5 443 6.6E-156 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 444 1.5E-139 T 21-04-2016 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 Gene3D G3DSA:3.50.50.60 3 136 6.9E-44 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 SUPERFAMILY SSF55424 327 443 2.58E-32 T 21-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 Gene3D G3DSA:3.30.390.30 318 441 2.2E-37 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PANTHER PTHR22912:SF125 5 443 6.6E-156 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 311 5.4E-71 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 9.8E-36 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 9.8E-36 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 9.8E-36 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 9.8E-36 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.8E-36 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PIRSF PIRSF000350 1 443 3.7E-86 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 327 348 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 250 264 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 169 194 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 414 434 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 407 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 291 298 2.8E-66 T 21-04-2016 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 Gene3D G3DSA:3.50.50.60 137 317 3.5E-56 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 SUPERFAMILY SSF51905 3 321 2.33E-62 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 21-04-2016 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 HSISS4_RS03225 6a9d4144a59532ffd25996e14b0b88e8 446 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 439 6.4E-30 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS04650 dea3740d26e525c27df57be960487f20 330 Pfam PF11380 Stealth protein CR2, conserved region 2 43 144 4.1E-42 T 21-04-2016 IPR021520 Stealth protein CR2, conserved region 2 GO:0016772 KEGG: 00563+2.7.-.- HSISS4_RS04650 dea3740d26e525c27df57be960487f20 330 PANTHER PTHR24045 6 141 9.0E-41 T 21-04-2016 HSISS4_RS04650 dea3740d26e525c27df57be960487f20 330 PANTHER PTHR24045:SF0 6 141 9.0E-41 T 21-04-2016 HSISS4_RS04650 dea3740d26e525c27df57be960487f20 330 Pfam PF17101 Stealth protein CR1, conserved region 1 4 30 6.7E-9 T 21-04-2016 IPR031358 Stealth protein CR1, conserved region 1 KEGG: 00563+2.7.-.- HSISS4_RS07550 67676b12680469ac892aa00c543e40aa 126 Gene3D G3DSA:2.30.29.50 4 103 1.4E-42 T 21-04-2016 IPR012544 Bacterial Pleckstrin homology domain HSISS4_RS07550 67676b12680469ac892aa00c543e40aa 126 Pfam PF08000 Bacterial PH domain 2 123 1.7E-45 T 21-04-2016 IPR012544 Bacterial Pleckstrin homology domain HSISS4_RS07550 67676b12680469ac892aa00c543e40aa 126 SUPERFAMILY SSF50729 6 125 8.61E-39 T 21-04-2016 IPR011993 PH domain-like HSISS4_RS07550 67676b12680469ac892aa00c543e40aa 126 PANTHER PTHR35796 1 125 9.8E-40 T 21-04-2016 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 PANTHER PTHR11986:SF79 8 376 2.8E-157 T 21-04-2016 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 202 239 - T 21-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 SUPERFAMILY SSF53383 2 375 8.07E-112 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 PANTHER PTHR11986 8 376 2.8E-157 T 21-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 376 42.308 T 21-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 Gene3D G3DSA:3.90.1150.10 4 46 6.5E-31 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 Gene3D G3DSA:3.90.1150.10 286 375 6.5E-31 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 Gene3D G3DSA:3.40.640.10 47 281 3.1E-81 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 Pfam PF00202 Aminotransferase class-III 10 374 5.4E-107 T 21-04-2016 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 HSISS4_RS02180 19c456ea97a623667eb8a29200e447c3 376 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 5 375 2.3E-139 T 21-04-2016 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 6 463 1.3E-202 T 21-04-2016 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 SUPERFAMILY SSF55604 8 81 1.03E-19 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 PANTHER PTHR30175 1 483 0.0 T 21-04-2016 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 PANTHER PTHR30175 500 595 0.0 T 21-04-2016 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 20 37 - T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 562 574 - T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 499 623 1.2E-49 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 SUPERFAMILY SSF51261 493 629 6.28E-52 T 21-04-2016 IPR011055 Duplicated hybrid motif HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 Gene3D G3DSA:2.70.70.10 496 644 1.4E-57 T 21-04-2016 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 Gene3D G3DSA:3.30.1360.60 3 82 8.2E-25 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 29 109 2.2E-13 T 21-04-2016 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 Pfam PF02378 Phosphotransferase system, EIIC 111 401 4.1E-34 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 PANTHER PTHR30175:SF4 1 483 0.0 T 21-04-2016 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 PANTHER PTHR30175:SF4 500 595 0.0 T 21-04-2016 HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 500 620 3.7E-41 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS09170 673f14e046ce1ddc18ed1c3bd9edc18b 649 Pfam PF00367 phosphotransferase system, EIIB 9 42 2.2E-13 T 21-04-2016 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 118 130 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 72 83 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 162 175 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 45 54 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 97 105 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 5.1E-31 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 162 175 2.1E-12 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 2.1E-12 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 72 83 2.1E-12 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 Pfam PF00117 Glutamine amidotransferase class-I 4 183 1.1E-49 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 Gene3D G3DSA:3.40.50.880 1 185 2.3E-61 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PANTHER PTHR11922 1 188 8.9E-71 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 184 4.1E-55 T 21-04-2016 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PANTHER PTHR11922:SF7 1 188 8.9E-71 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 72 88 2.1E-7 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 2.1E-7 T 21-04-2016 HSISS4_RS07670 7cae44e8195a547b05e6b24ec5672fea 188 SUPERFAMILY SSF52317 1 187 3.36E-52 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 PANTHER PTHR30543:SF6 1 194 7.4E-87 T 21-04-2016 HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 SUPERFAMILY SSF52218 1 173 4.39E-36 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 Pfam PF03358 NADPH-dependent FMN reductase 1 147 9.7E-31 T 21-04-2016 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 Gene3D G3DSA:3.30.450.20 223 373 1.2E-37 T 21-04-2016 HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 Pfam PF13596 PAS domain 242 355 1.2E-27 T 21-04-2016 HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 PANTHER PTHR30543 1 194 7.4E-87 T 21-04-2016 HSISS4_RS08890 f9eaafefdfecda75634626ff65ee3885 415 Gene3D G3DSA:3.40.50.360 1 184 1.1E-43 T 21-04-2016 IPR029039 Flavoprotein-like domain HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 Pfam PF02540 NAD synthase 23 264 1.3E-64 T 21-04-2016 IPR022310 NAD/GMP synthase HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 SUPERFAMILY SSF52402 3 272 9.31E-81 T 21-04-2016 HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 PANTHER PTHR23090:SF7 1 273 3.1E-157 T 21-04-2016 HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 PANTHER PTHR23090 1 273 3.1E-157 T 21-04-2016 HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 17 267 29.851 T 21-04-2016 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 Gene3D G3DSA:3.40.50.620 4 268 3.1E-66 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS01095 fc75f7050ee2cab257bceeb987a51229 273 TIGRFAM TIGR00552 nadE: NAD+ synthetase 17 273 1.9E-71 T 21-04-2016 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|UniPathway: UPA00253 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 SUPERFAMILY SSF82549 1 279 7.85E-66 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 2.5E-54 T 21-04-2016 IPR003797 DegV HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 272 1.2E-67 T 21-04-2016 IPR003797 DegV HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 Gene3D G3DSA:3.40.50.10440 67 153 4.9E-31 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 Gene3D G3DSA:3.40.50.10440 1 29 4.9E-31 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 Gene3D G3DSA:2.20.28.50 30 66 3.7E-14 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 Gene3D G3DSA:3.30.1180.10 155 278 3.9E-36 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 PANTHER PTHR33434:SF3 1 274 4.4E-79 T 21-04-2016 HSISS4_RS03150 1dd8d7f4da35768365c9a32688a0edff 280 PANTHER PTHR33434 1 274 4.4E-79 T 21-04-2016 HSISS4_RS06105 1c80f3d3e927f37587a2bc0a8ff99d49 149 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 56 101 - T 21-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HSISS4_RS06105 1c80f3d3e927f37587a2bc0a8ff99d49 149 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 26 106 1.7E-4 T 21-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HSISS4_RS06105 1c80f3d3e927f37587a2bc0a8ff99d49 149 SUPERFAMILY SSF53927 3 137 9.03E-27 T 21-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HSISS4_RS06105 1c80f3d3e927f37587a2bc0a8ff99d49 149 Gene3D G3DSA:3.40.140.10 1 145 2.5E-40 T 21-04-2016 HSISS4_RS04685 4211efb91a74590cfe679e100a9b53b9 378 PANTHER PTHR21716 41 376 1.1E-46 T 21-04-2016 IPR002549 Transmembrane protein TqsA-like HSISS4_RS04685 4211efb91a74590cfe679e100a9b53b9 378 Pfam PF01594 Domain of unknown function DUF20 30 359 8.7E-44 T 21-04-2016 IPR002549 Transmembrane protein TqsA-like HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 SUPERFAMILY SSF50249 2 58 8.57E-16 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 433 443 - T 21-04-2016 IPR030391 RNA methyltransferase TrmA, conserved site HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 381 412 - T 21-04-2016 IPR030390 RNA methyltransferase TrmA, active site HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 PANTHER PTHR11061 2 450 3.8E-162 T 21-04-2016 HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 Gene3D G3DSA:3.40.50.150 244 449 3.3E-67 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 15 443 9.0E-136 T 21-04-2016 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 Gene3D G3DSA:2.40.50.140 2 70 4.6E-23 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 PANTHER PTHR11061:SF30 2 450 3.8E-162 T 21-04-2016 HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 273 450 1.7E-23 T 21-04-2016 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 HSISS4_RS03075 c249712a3a74bc64f15963d07328e297 451 SUPERFAMILY SSF53335 73 450 5.97E-78 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS05775 4501fca8002b6f28d62f1e32f077fcdb 203 PANTHER PTHR34135:SF3 1 200 1.7E-56 T 21-04-2016 HSISS4_RS05775 4501fca8002b6f28d62f1e32f077fcdb 203 PANTHER PTHR34135 1 200 1.7E-56 T 21-04-2016 HSISS4_RS05775 4501fca8002b6f28d62f1e32f077fcdb 203 Gene3D G3DSA:1.10.530.10 28 151 3.8E-6 T 21-04-2016 HSISS4_RS05775 4501fca8002b6f28d62f1e32f077fcdb 203 SUPERFAMILY SSF53955 34 151 1.31E-9 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS05775 4501fca8002b6f28d62f1e32f077fcdb 203 Pfam PF13702 Lysozyme-like 29 193 6.1E-59 T 21-04-2016 HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 Gene3D G3DSA:3.90.1150.10 244 367 7.0E-30 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 Pfam PF00266 Aminotransferase class-V 2 360 3.7E-71 T 21-04-2016 IPR000192 Aminotransferase class V domain HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 PANTHER PTHR11601 1 368 1.6E-138 T 21-04-2016 HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 PIRSF PIRSF005572 1 370 9.0E-111 T 21-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 SUPERFAMILY SSF53383 1 368 6.12E-95 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 Gene3D G3DSA:3.40.640.10 15 243 2.7E-80 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS07040 6b78975390d0f2a011868ed917a3cd54 370 PANTHER PTHR11601:SF20 1 368 1.6E-138 T 21-04-2016 HSISS4_RS05915 e4b3b5ec353a6f7d7844d2e648698414 172 PANTHER PTHR23091:SF257 1 163 1.1E-36 T 21-04-2016 HSISS4_RS05915 e4b3b5ec353a6f7d7844d2e648698414 172 SUPERFAMILY SSF55729 1 165 1.55E-28 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05915 e4b3b5ec353a6f7d7844d2e648698414 172 Gene3D G3DSA:3.40.630.30 1 161 7.0E-34 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05915 e4b3b5ec353a6f7d7844d2e648698414 172 PANTHER PTHR23091 1 163 1.1E-36 T 21-04-2016 HSISS4_RS05915 e4b3b5ec353a6f7d7844d2e648698414 172 Pfam PF00583 Acetyltransferase (GNAT) family 66 147 5.3E-11 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 Pfam PF00483 Nucleotidyl transferase 22 157 1.4E-10 T 21-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 Gene3D G3DSA:3.90.550.10 304 347 1.5E-31 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 Gene3D G3DSA:3.90.550.10 21 271 1.5E-31 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 4 371 9.2E-135 T 21-04-2016 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 SUPERFAMILY SSF53448 22 260 6.49E-34 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 SUPERFAMILY SSF53448 321 337 6.49E-34 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 PANTHER PTHR22572:SF9 6 378 9.1E-122 T 21-04-2016 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 SUPERFAMILY SSF51161 228 374 4.57E-12 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS06845 901e89ddf109a41114a70175bbfb003a 378 PANTHER PTHR22572 6 378 9.1E-122 T 21-04-2016 HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 PANTHER PTHR18895 1 242 1.2E-96 T 21-04-2016 HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 Gene3D G3DSA:3.40.50.150 34 245 1.3E-71 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 Pfam PF05175 Methyltransferase small domain 21 174 2.3E-14 T 21-04-2016 IPR007848 Methyltransferase small domain GO:0008168 HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 SUPERFAMILY SSF53335 16 199 1.81E-32 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 120 126 - T 21-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HSISS4_RS07530 3d149cd78c250b1ca2bc049d5e2f1c4f 254 PANTHER PTHR18895:SF75 1 242 1.2E-96 T 21-04-2016 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 Gene3D G3DSA:3.90.1150.10 246 363 6.2E-35 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 189 203 - T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 8 362 1.6E-120 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 PANTHER PTHR11808 1 363 8.6E-160 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 SUPERFAMILY SSF53383 7 362 2.86E-94 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 PANTHER PTHR11808:SF15 1 363 8.6E-160 T 21-04-2016 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 PIRSF PIRSF001434 1 364 2.4E-114 T 21-04-2016 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 HSISS4_RS01595 e996c081940fea468be490ca16917eac 364 Gene3D G3DSA:3.40.640.10 6 245 3.9E-83 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 SUPERFAMILY SSF82185 53 134 2.88E-19 T 21-04-2016 HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 SMART SM00698 100 121 0.43 T 21-04-2016 IPR003409 MORN motif HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 SMART SM00698 77 98 0.23 T 21-04-2016 IPR003409 MORN motif HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 SMART SM00698 54 75 57.0 T 21-04-2016 IPR003409 MORN motif HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 PANTHER PTHR23084:SF131 56 136 2.3E-18 T 21-04-2016 HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 PIRSF PIRSF034300 11 136 7.4E-47 T 21-04-2016 IPR014590 Uncharacterised conserved protein MORN repeat-containing HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 Gene3D G3DSA:2.20.110.10 52 136 7.6E-22 T 21-04-2016 HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 PANTHER PTHR23084 56 136 2.3E-18 T 21-04-2016 HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 Pfam PF02493 MORN repeat 79 96 0.012 T 21-04-2016 IPR003409 MORN motif HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 Pfam PF02493 MORN repeat 102 119 5.5E-4 T 21-04-2016 IPR003409 MORN motif HSISS4_RS09370 4bde41ab1a0174d7c8f4d5a7000f4b80 136 Pfam PF02493 MORN repeat 56 78 1.1E-4 T 21-04-2016 IPR003409 MORN motif HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 SUPERFAMILY SSF54980 403 518 1.97E-29 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Gene3D G3DSA:3.30.70.240 405 481 1.1E-33 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Pfam PF00679 Elongation factor G C-terminus 401 480 4.0E-24 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Gene3D G3DSA:2.40.30.10 210 308 7.5E-27 T 21-04-2016 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 SMART SM00838 400 485 4.7E-6 T 21-04-2016 IPR000640 Translation elongation factor EFG, V domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Pfam PF00009 Elongation factor Tu GTP binding domain 7 200 9.3E-56 T 21-04-2016 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Pfam PF03144 Elongation factor Tu domain 2 224 294 2.7E-14 T 21-04-2016 IPR004161 Translation elongation factor EFTu/EF1A, domain 2 GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 149 3.4E-24 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 21-04-2016 IPR031157 Tr-type G domain, conserved site HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PRINTS PR00315 GTP-binding elongation factor signature 10 23 1.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PRINTS PR00315 GTP-binding elongation factor signature 54 62 1.9E-14 T 21-04-2016 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 8 603 5.1E-290 T 21-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Gene3D G3DSA:3.30.70.870 309 404 9.5E-38 T 21-04-2016 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PANTHER PTHR23115 189 598 2.3E-291 T 21-04-2016 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PANTHER PTHR23115 1 173 2.3E-291 T 21-04-2016 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 SUPERFAMILY SSF54980 307 392 1.55E-14 T 21-04-2016 IPR009022 Elongation factor G, III-V domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 SUPERFAMILY SSF50447 155 304 1.83E-32 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 SUPERFAMILY SSF52540 3 212 1.49E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PANTHER PTHR23115:SF14 189 598 2.3E-291 T 21-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 PANTHER PTHR23115:SF14 1 173 2.3E-291 T 21-04-2016 IPR006298 GTP-binding protein TypA GO:0005525 HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Gene3D G3DSA:3.40.50.300 4 209 3.8E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03610 84792da4cc749d563010f9bbe4bd8d09 616 Gene3D G3DSA:2.40.50.250 488 582 9.2E-38 T 21-04-2016 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 Pfam PF00137 ATP synthase subunit C 6 62 7.9E-8 T 21-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 PRINTS PR00124 ATP synthase C subunit signature 41 65 8.2E-6 T 21-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 PRINTS PR00124 ATP synthase C subunit signature 3 22 8.2E-6 T 21-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 PRINTS PR00124 ATP synthase C subunit signature 24 39 8.2E-6 T 21-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 Gene3D G3DSA:1.20.20.10 5 62 6.3E-17 T 21-04-2016 IPR000454 ATPase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 HSISS4_RS02240 839836fe7a61697430c449470aa2bdfd 65 SUPERFAMILY SSF81333 6 62 1.44E-12 T 21-04-2016 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 HSISS4_RS01425 df6ad93bcebcd4cb0c746f74b86e3fce 178 Pfam PF02620 Uncharacterized ACR, COG1399 54 174 2.0E-23 T 21-04-2016 IPR003772 Protein of unknown function DUF177 HSISS4_RS01425 df6ad93bcebcd4cb0c746f74b86e3fce 178 PANTHER PTHR41303 1 178 1.0E-37 T 21-04-2016 HSISS4_RS01425 df6ad93bcebcd4cb0c746f74b86e3fce 178 PANTHER PTHR41303:SF1 1 178 1.0E-37 T 21-04-2016 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 335 21.316 T 21-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 Pfam PF00953 Glycosyl transferase family 4 84 248 6.8E-39 T 21-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 PANTHER PTHR22926 1 334 6.4E-117 T 21-04-2016 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 5.3E-5 T 21-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 21-04-2016 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 PANTHER PTHR22926:SF5 1 334 6.4E-117 T 21-04-2016 HSISS4_RS08140 cce10334990f10579c495816a2af2c68 340 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 332 3.2E-73 T 21-04-2016 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 Pfam PF01740 STAS domain 437 492 2.4E-5 T 21-04-2016 IPR002645 STAS domain HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 PANTHER PTHR11814 15 503 2.9E-212 T 21-04-2016 IPR001902 SLC26A/SulP transporter GO:0008271|GO:0008272|GO:0016020|GO:0055085 Reactome: REACT_15518 HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 Gene3D G3DSA:3.30.750.24 437 496 4.9E-8 T 21-04-2016 IPR002645 STAS domain HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 SUPERFAMILY SSF52091 435 496 2.16E-9 T 21-04-2016 IPR002645 STAS domain HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 PANTHER PTHR11814:SF112 15 503 2.9E-212 T 21-04-2016 HSISS4_RS03300 2a034be807e980e9d2433d37ac2ef045 503 Pfam PF00916 Sulfate permease family 23 386 4.3E-81 T 21-04-2016 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 HSISS4_RS04595 3751992dee301da98f81ca0cca2eee52 230 Pfam PF02706 Chain length determinant protein 10 145 2.8E-26 T 21-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 HSISS4_RS04595 3751992dee301da98f81ca0cca2eee52 230 TIGRFAM TIGR01006 polys_exp_MPA1: polysaccharide export protein, MPA1 family 1 229 2.8E-102 T 21-04-2016 IPR005701 Polysaccharide export protein MPA1-like GO:0006859|GO:0015542|GO:0016021 HSISS4_RS04595 3751992dee301da98f81ca0cca2eee52 230 PANTHER PTHR32309 7 228 2.5E-24 T 21-04-2016 HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 PANTHER PTHR23407:SF1 1 175 5.3E-43 T 21-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 173 9.6E-50 T 21-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 2 173 4.9E-41 T 21-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 Gene3D G3DSA:3.40.50.10420 1 173 4.7E-47 T 21-04-2016 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 PANTHER PTHR23407 1 175 5.3E-43 T 21-04-2016 HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 SUPERFAMILY SSF100950 1 173 3.07E-47 T 21-04-2016 HSISS4_RS08920 6c3f23709e1d9cc6375ab2a7d3ef618f 175 PIRSF PIRSF006806 1 175 6.8E-44 T 21-04-2016 IPR002698 5-formyltetrahydrofolate cyclo-ligase HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PANTHER PTHR11733 6 631 1.9E-140 T 21-04-2016 IPR000718 Peptidase M13 GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PANTHER PTHR11733:SF65 6 631 1.9E-140 T 21-04-2016 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 Gene3D G3DSA:3.40.390.10 429 631 9.2E-92 T 21-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 Gene3D G3DSA:3.40.390.10 272 387 9.2E-92 T 21-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 SUPERFAMILY SSF55486 5 631 6.74E-192 T 21-04-2016 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 430 442 2.8E-21 T 21-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 469 485 2.8E-21 T 21-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 448 460 2.8E-21 T 21-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 PRINTS PR00786 Neprilysin metalloprotease (M13) family signature 539 550 2.8E-21 T 21-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 Pfam PF01431 Peptidase family M13 438 628 1.2E-62 T 21-04-2016 IPR018497 Peptidase M13, C-terminal domain GO:0004222|GO:0006508 HSISS4_RS09160 dcd02a0cddca8b32b2ae35b257b51879 631 Pfam PF05649 Peptidase family M13 5 384 1.8E-62 T 21-04-2016 IPR008753 Peptidase M13, N-terminal domain GO:0006508 HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 Pfam PF04851 Type III restriction enzyme, res subunit 260 424 1.6E-15 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 SUPERFAMILY SSF52540 525 704 6.69E-38 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 SMART SM00487 258 454 1.1E-23 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 SMART SM00490 560 657 2.8E-11 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 Gene3D G3DSA:3.40.50.300 246 447 7.0E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 TIGRFAM TIGR00595 priA: primosomal protein N' 285 794 4.2E-199 T 21-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 797 24.272 T 21-04-2016 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 Pfam PF00271 Helicase conserved C-terminal domain 568 656 2.7E-9 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 PANTHER PTHR30580 1 798 3.4E-274 T 21-04-2016 HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 SUPERFAMILY SSF52540 215 444 3.26E-39 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06935 ad1fe8e7c205b8ed925d6a38158f1420 798 Gene3D G3DSA:3.40.50.300 523 700 5.0E-38 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 7 273 2.4E-66 T 21-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 Gene3D G3DSA:2.40.30.90 170 276 3.1E-26 T 21-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 SUPERFAMILY SSF101852 170 276 3.66E-28 T 21-04-2016 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 PANTHER PTHR35092:SF2 2 282 2.5E-172 T 21-04-2016 HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 PIRSF PIRSF006779 1 278 1.2E-94 T 21-04-2016 IPR002747 SAM-dependent chlorinase/fluorinase HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 SUPERFAMILY SSF102522 4 167 9.42E-53 T 21-04-2016 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal HSISS4_RS01390 f1b4125f01757159bbc08b67b5f71175 282 PANTHER PTHR35092 2 282 2.5E-172 T 21-04-2016 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 PANTHER PTHR10438 6 101 3.1E-33 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 SUPERFAMILY SSF52833 4 103 1.79E-34 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 6 102 4.7E-31 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 Pfam PF00085 Thioredoxin 3 101 3.3E-28 T 21-04-2016 IPR013766 Thioredoxin domain GO:0045454 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 Gene3D G3DSA:3.40.30.10 3 102 3.6E-33 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 PIRSF PIRSF000077 1 103 3.8E-33 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 PRINTS PR00421 Thioredoxin family signature 27 36 1.1E-6 T 21-04-2016 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 PRINTS PR00421 Thioredoxin family signature 19 27 1.1E-6 T 21-04-2016 HSISS4_RS00585 e5290559a6620e917cff90477d36051d 104 PRINTS PR00421 Thioredoxin family signature 67 78 1.1E-6 T 21-04-2016 HSISS4_RS03495 77a9f82fe1b37d073ce50e47d92b45f8 304 SUPERFAMILY SSF56784 14 241 1.16E-20 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS03495 77a9f82fe1b37d073ce50e47d92b45f8 304 Pfam PF12710 haloacid dehalogenase-like hydrolase 19 218 1.0E-9 T 21-04-2016 HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 5 42 4.1E-7 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 99 131 1.1E-4 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 Pfam PF04650 YSIRK type signal peptide 9 33 8.2E-9 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 Pfam PF05342 M26 IgA1-specific Metallo-endopeptidase N-terminal region 757 1005 1.3E-86 T 21-04-2016 IPR008006 Peptidase M26, N-terminal domain GO:0004222|GO:0008270|GO:0016021 HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 Pfam PF07580 M26 IgA1-specific Metallo-endopeptidase C-terminal region 1312 2050 3.0E-252 T 21-04-2016 IPR011505 Peptidase M26, C-terminal domain GO:0004222|GO:0005576|GO:0005618|GO:0008270 HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 SMART SM01208 534 613 1.1E-12 T 21-04-2016 IPR011098 G5 domain HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 SMART SM01208 614 693 9.3E-11 T 21-04-2016 IPR011098 G5 domain HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 Pfam PF07501 G5 domain 539 612 3.9E-11 T 21-04-2016 IPR011098 G5 domain HSISS4_RS06785 5bceda59b13006bbd3917b8f0adf1db4 2051 Pfam PF07501 G5 domain 618 692 2.7E-10 T 21-04-2016 IPR011098 G5 domain HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 PANTHER PTHR10108 193 244 6.5E-48 T 21-04-2016 HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 PANTHER PTHR10108 1 167 6.5E-48 T 21-04-2016 HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 Pfam PF13649 Methyltransferase domain 41 135 1.4E-16 T 21-04-2016 HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 Gene3D G3DSA:3.40.50.150 3 246 7.6E-43 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 SUPERFAMILY SSF53335 4 246 2.89E-47 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 PANTHER PTHR10108:SF872 193 244 6.5E-48 T 21-04-2016 HSISS4_RS07810 1a3dae387621a45a56e1a7fce633228f 246 PANTHER PTHR10108:SF872 1 167 6.5E-48 T 21-04-2016 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 SUPERFAMILY SSF54747 3 72 1.19E-29 T 21-04-2016 IPR020784 Ribosomal protein L11, N-terminal HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 PANTHER PTHR11661 1 139 1.2E-71 T 21-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 140 1.7E-63 T 21-04-2016 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 Gene3D G3DSA:1.10.10.250 72 139 5.7E-33 T 21-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 SMART SM00649 9 140 2.1E-85 T 21-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 31.313 T 21-04-2016 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 6.0E-16 T 21-04-2016 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 Gene3D G3DSA:3.30.1550.10 2 71 9.4E-38 T 21-04-2016 IPR020784 Ribosomal protein L11, N-terminal HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.2E-25 T 21-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 4.2E-30 T 21-04-2016 IPR020784 Ribosomal protein L11, N-terminal HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 SUPERFAMILY SSF46906 67 139 4.58E-27 T 21-04-2016 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 HSISS4_RS08850 7c62ddaa881f6a910656438f9e153b71 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 21-04-2016 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS03865 a2f746e6587d2ccd40d940dba19bedf8 244 PANTHER PTHR21039 1 240 2.2E-18 T 21-04-2016 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15|UniPathway: UPA00031 HSISS4_RS03865 a2f746e6587d2ccd40d940dba19bedf8 244 Gene3D G3DSA:3.20.20.140 3 244 5.2E-14 T 21-04-2016 HSISS4_RS03865 a2f746e6587d2ccd40d940dba19bedf8 244 SUPERFAMILY SSF89550 3 243 1.44E-22 T 21-04-2016 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 21-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 180 37.834 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 188 2.6E-65 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 PANTHER PTHR17224:SF1 3 188 7.3E-79 T 21-04-2016 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 Gene3D G3DSA:3.40.50.1470 2 188 4.2E-72 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 SUPERFAMILY SSF53178 2 188 1.83E-68 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 Pfam PF01195 Peptidyl-tRNA hydrolase 4 186 1.4E-58 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 21-04-2016 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 HSISS4_RS00025 3927c2ab74a3f759eceb964926be0a80 189 PANTHER PTHR17224 3 188 7.3E-79 T 21-04-2016 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 HSISS4_RS09555 80efdce30853d2a310490921c2bfa600 108 PANTHER PTHR33169 8 100 1.1E-22 T 21-04-2016 HSISS4_RS09555 80efdce30853d2a310490921c2bfa600 108 Gene3D G3DSA:1.10.10.10 9 101 2.9E-27 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS09555 80efdce30853d2a310490921c2bfa600 108 PANTHER PTHR33169:SF3 8 100 1.1E-22 T 21-04-2016 HSISS4_RS09555 80efdce30853d2a310490921c2bfa600 108 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 2.6E-19 T 21-04-2016 IPR005149 Transcription regulator PadR, N-terminal HSISS4_RS09555 80efdce30853d2a310490921c2bfa600 108 SUPERFAMILY SSF46785 10 105 3.04E-22 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 SUPERFAMILY SSF50249 96 199 1.13E-27 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 Gene3D G3DSA:2.40.50.140 95 204 3.3E-37 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 Gene3D G3DSA:3.30.1940.10 20 90 1.2E-27 T 21-04-2016 IPR027855 Domain of unknown function DUF4479 HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 Pfam PF14794 Domain of unknown function (DUF4479) 23 90 2.2E-27 T 21-04-2016 IPR027855 Domain of unknown function DUF4479 HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 Pfam PF01588 Putative tRNA binding domain 96 197 4.7E-18 T 21-04-2016 IPR002547 tRNA-binding domain GO:0000049 Reactome: REACT_71 HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 PANTHER PTHR10947:SF0 86 197 1.8E-18 T 21-04-2016 HSISS4_RS08985 26853c55559012d4b0a4ee8e529a5625 207 PANTHER PTHR10947 86 197 1.8E-18 T 21-04-2016 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 2.2E-55 T 21-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 Gene3D G3DSA:3.100.10.10 32 146 3.3E-42 T 21-04-2016 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 SUPERFAMILY SSF52080 4 144 1.07E-49 T 21-04-2016 IPR021131 Ribosomal protein L18e/L15P HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 PANTHER PTHR12934 1 146 6.4E-78 T 21-04-2016 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 22.289 T 21-04-2016 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 21-04-2016 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09255 90358872bb2d20e1bc0a5ee750f7f87a 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.0E-38 T 21-04-2016 IPR021131 Ribosomal protein L18e/L15P HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 Pfam PF03960 ArsC family 9 113 9.2E-20 T 21-04-2016 IPR006660 Arsenate reductase-like HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 SUPERFAMILY SSF52833 1 123 1.48E-34 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 PANTHER PTHR30041:SF5 1 130 1.5E-65 T 21-04-2016 HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 Gene3D G3DSA:3.40.30.10 1 114 9.2E-32 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 PANTHER PTHR30041 1 130 1.5E-65 T 21-04-2016 HSISS4_RS00350 6c9367c9c375d0235a2defecbc52f707 132 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 114 8.6E-35 T 21-04-2016 IPR006504 Transcriptional regulator Spx/MgsR HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 71 83 1.3E-5 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.3E-5 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 10 176 9.0E-36 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 Pfam PF00717 Peptidase S24-like 41 95 5.5E-6 T 21-04-2016 IPR019759 Peptidase S24/S26A/S26B HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 Gene3D G3DSA:2.10.109.10 136 182 1.3E-17 T 21-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 Gene3D G3DSA:2.10.109.10 23 81 1.3E-17 T 21-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 SUPERFAMILY SSF51306 24 182 1.44E-34 T 21-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HSISS4_RS04470 4f5254f6a45b58ec5d056b851ff8d8d1 185 PANTHER PTHR12383 1 183 5.6E-21 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 Gene3D G3DSA:3.40.50.1100 138 326 6.3E-46 T 21-04-2016 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 SUPERFAMILY SSF55021 333 411 1.69E-11 T 21-04-2016 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 TIGRFAM TIGR02079 THD1: threonine dehydratase 6 416 3.5E-179 T 21-04-2016 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 SUPERFAMILY SSF53686 5 360 1.7E-97 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 PANTHER PTHR10314:SF30 1 362 2.5E-160 T 21-04-2016 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 310 5.7E-75 T 21-04-2016 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 PANTHER PTHR10314 1 362 2.5E-160 T 21-04-2016 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 Gene3D G3DSA:3.40.50.1100 50 137 1.7E-32 T 21-04-2016 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 323 415 8.6E-26 T 21-04-2016 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19|UniPathway: UPA00047 HSISS4_RS00795 71d9ce2c0ba4ad1f003b8743c4dd3554 416 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 21-04-2016 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Gene3D G3DSA:1.10.3090.10 148 367 1.8E-49 T 21-04-2016 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 SUPERFAMILY SSF81891 145 399 5.89E-57 T 21-04-2016 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 174 232 4.7E-18 T 21-04-2016 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 PANTHER PTHR13734 12 243 7.0E-72 T 21-04-2016 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 250 396 6.4E-48 T 21-04-2016 IPR032810 CCA-adding enzyme, C-terminal HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Gene3D G3DSA:3.30.460.10 11 147 8.8E-46 T 21-04-2016 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Pfam PF01743 Poly A polymerase head domain 27 147 1.6E-35 T 21-04-2016 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 SUPERFAMILY SSF81301 10 144 3.81E-41 T 21-04-2016 HSISS4_RS01940 6368e301ac6dfa0986fb0d5b2e839114 400 Hamap MF_01263 CCA-adding enzyme [cca]. 7 400 43.396 T 21-04-2016 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 Gene3D G3DSA:1.10.620.20 4 280 7.0E-86 T 21-04-2016 IPR012348 Ribonucleotide reductase-related GO:0016491|GO:0055114 Reactome: REACT_1698 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 Pfam PF00268 Ribonucleotide reductase, small chain 8 278 2.0E-83 T 21-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 PIRSF PIRSF000355 1 314 2.1E-73 T 21-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 TIGRFAM TIGR04171 RNR_1b_NrdF: ribonucleoside-diphosphate reductase, class 1b, beta subunit 5 316 1.0E-149 T 21-04-2016 IPR026494 Ribonucleoside reductase subunit beta, NrdF GO:0005971|GO:0009263 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|UniPathway: UPA00326 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 PANTHER PTHR23409 8 318 1.7E-85 T 21-04-2016 IPR000358 Ribonucleotide reductase small subunit GO:0009186|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: REACT_1698|UniPathway: UPA00326 HSISS4_RS03675 1820c18d3c1f7c92a2871f9eba770a3e 319 SUPERFAMILY SSF47240 2 316 5.46E-100 T 21-04-2016 IPR009078 Ferritin-like superfamily HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 Pfam PF00288 GHMP kinases N terminal domain 104 160 1.2E-8 T 21-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 TIGRFAM TIGR01220 Pmev_kin_Gr_pos: phosphomevalonate kinase 11 326 4.3E-56 T 21-04-2016 IPR005917 Phosphomevalonate kinase, Gram-positive KEGG: 00900+2.7.4.2|MetaCyc: PWY-7391|MetaCyc: PWY-922|UniPathway: UPA00057 HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 SUPERFAMILY SSF55060 200 329 2.4E-27 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 Gene3D G3DSA:3.30.70.890 202 329 5.4E-36 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 SUPERFAMILY SSF54211 10 194 4.71E-41 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS02595 9c767fe0dfa6705674e39c6ba66367f7 331 Gene3D G3DSA:3.30.230.10 10 194 1.9E-62 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 PANTHER PTHR10815 1 164 1.6E-44 T 21-04-2016 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 Gene3D G3DSA:2.30.37.60 8 63 0.001 T 21-04-2016 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 157 1.1E-25 T 21-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 PANTHER PTHR10815:SF5 1 164 1.6E-44 T 21-04-2016 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 SUPERFAMILY SSF46767 78 160 3.53E-25 T 21-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 1 74 1.4E-4 T 21-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 SUPERFAMILY SSF53155 3 82 2.75E-15 T 21-04-2016 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 Gene3D G3DSA:1.10.10.10 78 163 7.1E-30 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 128 134 - T 21-04-2016 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 HSISS4_RS07300 96ae10e5bbae4bd1b49204c99c4e343c 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 80 159 2.4E-25 T 21-04-2016 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 222 1.0E-19 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 SUPERFAMILY SSF52172 1 179 2.11E-33 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 PANTHER PTHR26402 2 226 2.7E-65 T 21-04-2016 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 Gene3D G3DSA:3.40.50.2300 1 121 7.4E-31 T 21-04-2016 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 Pfam PF00072 Response regulator receiver domain 4 111 1.4E-20 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 SMART SM00448 2 111 2.6E-28 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 Gene3D G3DSA:1.10.10.10 125 225 5.2E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 SMART SM00862 147 223 8.0E-21 T 21-04-2016 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 HSISS4_RS06330 779c6e7998dbcd5e12860a09d4f26465 227 PANTHER PTHR26402:SF578 2 226 2.7E-65 T 21-04-2016 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 SUPERFAMILY SSF52540 373 616 1.3E-87 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 SUPERFAMILY SSF90123 14 334 4.71E-70 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 Pfam PF00005 ABC transporter 399 548 6.7E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 PANTHER PTHR24221 2 345 8.0E-214 T 21-04-2016 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 PANTHER PTHR24221 371 616 8.0E-214 T 21-04-2016 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 PANTHER PTHR24221:SF271 2 345 8.0E-214 T 21-04-2016 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 PANTHER PTHR24221:SF271 371 616 8.0E-214 T 21-04-2016 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 SMART SM00382 408 609 4.7E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 Gene3D G3DSA:3.40.50.300 383 613 2.0E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 Pfam PF00664 ABC transporter transmembrane region 29 305 1.7E-39 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS06805 78ec3ec1d5fff5f979c97a3243df7c87 622 Gene3D G3DSA:1.20.1560.10 14 332 1.2E-69 T 21-04-2016 HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 208 2.4E-20 T 21-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 SUPERFAMILY SSF56300 1 241 1.67E-51 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 Gene3D G3DSA:3.60.21.10 4 244 7.1E-56 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 PANTHER PTHR11124 106 275 8.5E-78 T 21-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 PANTHER PTHR11124 1 75 8.5E-78 T 21-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 PIRSF PIRSF000883 3 250 8.7E-72 T 21-04-2016 IPR011152 Phosphoesterase MJ0912 HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 PANTHER PTHR11124:SF2 106 275 8.5E-78 T 21-04-2016 HSISS4_RS06475 e28c08d1929e9319f7a00b6ea1d016d7 277 PANTHER PTHR11124:SF2 1 75 8.5E-78 T 21-04-2016 HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 PANTHER PTHR42160:SF1 1 194 4.9E-93 T 21-04-2016 HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 Gene3D G3DSA:3.40.470.10 3 192 3.9E-35 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 SUPERFAMILY SSF52141 3 192 8.5E-47 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 Pfam PF03167 Uracil DNA glycosylase superfamily 31 185 1.8E-20 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 SMART SM00986 28 185 2.5E-26 T 21-04-2016 IPR005122 Uracil-DNA glycosylase-like HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 SMART SM00987 28 185 2.5E-26 T 21-04-2016 HSISS4_RS04535 293ab88a1e92e6245c5b15ae9f7610c4 194 PANTHER PTHR42160 1 194 4.9E-93 T 21-04-2016 HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 SUPERFAMILY SSF55826 7 155 1.18E-34 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 PIRSF PIRSF006181 5 157 1.7E-51 T 21-04-2016 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 PANTHER PTHR30411:SF0 4 157 1.8E-39 T 21-04-2016 HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 Pfam PF04073 Aminoacyl-tRNA editing domain 39 147 2.7E-19 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 PANTHER PTHR30411 4 157 1.8E-39 T 21-04-2016 HSISS4_RS03440 0e33193e65155231d56d1893248a142e 157 Gene3D G3DSA:3.90.960.10 3 156 7.1E-42 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 SUPERFAMILY SSF52402 3 163 6.4E-47 T 21-04-2016 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 115 126 - T 21-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 395 54.119 T 21-04-2016 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 PANTHER PTHR11587 1 394 7.2E-215 T 21-04-2016 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 Pfam PF00764 Arginosuccinate synthase 7 389 1.5E-171 T 21-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 21-04-2016 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 Gene3D G3DSA:3.90.1260.10 172 394 4.6E-89 T 21-04-2016 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 393 8.5E-161 T 21-04-2016 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 Gene3D G3DSA:3.40.50.620 4 169 1.9E-60 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 SUPERFAMILY SSF69864 171 395 8.63E-90 T 21-04-2016 HSISS4_RS08805 99297bd126ff29b84ff6f80c1425130c 399 PANTHER PTHR11587:SF2 1 394 7.2E-215 T 21-04-2016 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 PIRSF PIRSF001338 1 162 2.8E-69 T 21-04-2016 IPR024694 N5-carboxyaminoimidazole ribonucleotide mutase PurE GO:0006189|GO:0034023 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234|UniPathway: UPA00074 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 Pfam PF00731 AIR carboxylase 5 150 2.6E-64 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 PANTHER PTHR23046 1 162 3.7E-92 T 21-04-2016 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 SMART SM01001 3 154 1.2E-99 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 32.596 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 157 2.5E-65 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 PANTHER PTHR23046:SF2 1 162 3.7E-92 T 21-04-2016 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 SUPERFAMILY SSF52255 4 160 4.19E-66 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS00260 e9b71dd5afb2c18cb9c4ec12ad356747 162 Gene3D G3DSA:3.40.50.7700 2 161 4.2E-75 T 21-04-2016 IPR000031 Phosphoribosylaminoimidazole carboxylase PurE domain GO:0006189 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 PIRSF PIRSF000505 1 427 3.6E-109 T 21-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 21-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 PANTHER PTHR21090:SF5 5 427 7.1E-175 T 21-04-2016 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 SUPERFAMILY SSF55205 5 424 3.76E-134 T 21-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 421 1.5E-116 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 425 2.7E-132 T 21-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 Gene3D G3DSA:3.65.10.10 229 423 2.3E-52 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 PANTHER PTHR21090 5 427 7.1E-175 T 21-04-2016 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 Gene3D G3DSA:3.65.10.10 20 228 8.9E-61 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 427 33.254 T 21-04-2016 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03040 76c5236c1ce05770cf913828abecc981 427 ProSitePatterns PS00885 EPSP synthase signature 2. 337 355 - T 21-04-2016 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 PANTHER PTHR35795 3 194 2.6E-65 T 21-04-2016 HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 SMART SM00471 22 149 6.5E-7 T 21-04-2016 IPR003607 HD/PDEase domain HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 Pfam PF01966 HD domain 26 138 1.5E-11 T 21-04-2016 IPR006674 HD domain HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 19 188 2.5E-46 T 21-04-2016 IPR005249 Conserved hypothetical protein CHP00488 HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 Gene3D G3DSA:1.10.3210.10 3 193 1.4E-66 T 21-04-2016 IPR006674 HD domain HSISS4_RS07820 fb369012a2da473a2b03b4b930f6921c 196 SUPERFAMILY SSF109604 4 189 1.31E-33 T 21-04-2016 HSISS4_RS02420 fbb254d20f30f98f5991c44150432290 155 SMART SM00530 6 61 2.3E-8 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS02420 fbb254d20f30f98f5991c44150432290 155 SUPERFAMILY SSF47413 1 57 1.74E-13 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS02420 fbb254d20f30f98f5991c44150432290 155 Gene3D G3DSA:1.10.260.40 1 55 9.2E-17 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS02420 fbb254d20f30f98f5991c44150432290 155 Pfam PF01381 Helix-turn-helix 7 55 4.3E-11 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 Gene3D G3DSA:1.10.287.610 100 152 1.3E-26 T 21-04-2016 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.8E-42 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 21-04-2016 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 Pfam PF00318 Ribosomal protein S2 9 224 1.7E-98 T 21-04-2016 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 43.128 T 21-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 SUPERFAMILY SSF52313 6 230 1.57E-96 T 21-04-2016 IPR023591 Ribosomal protein S2, flavodoxin-like domain HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 Gene3D G3DSA:3.40.50.10490 158 245 1.7E-69 T 21-04-2016 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 Gene3D G3DSA:3.40.50.10490 23 99 1.7E-69 T 21-04-2016 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 7.5E-107 T 21-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HSISS4_RS00475 88742496cccde9043d8dbcf2446f78eb 255 PANTHER PTHR12534 1 255 3.7E-121 T 21-04-2016 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 Gene3D G3DSA:3.40.50.300 2 230 1.2E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 Pfam PF00005 ABC transporter 19 168 1.8E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 PANTHER PTHR24220 3 216 4.9E-61 T 21-04-2016 HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 SMART SM00382 26 216 1.1E-6 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 SUPERFAMILY SSF52540 3 231 2.3E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01355 b32c302f43a2c7e6b72ad0f9eadc47b1 238 PANTHER PTHR24220:SF66 3 216 4.9E-61 T 21-04-2016 HSISS4_RS03945 6c5fc8397685b9b39f0930b1fa94bdfa 421 Pfam PF14262 Domain of unknown function (DUF4353) 91 341 2.8E-70 T 21-04-2016 IPR025584 Carbohydrate-binding domain-containing protein Cthe_2159 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 349 372 - T 21-04-2016 IPR020595 MnmG-related, conserved site HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 9 447 36.07 T 21-04-2016 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 PANTHER PTHR11806 9 446 2.9E-242 T 21-04-2016 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 Pfam PF01134 Glucose inhibited division protein A 9 379 1.7E-113 T 21-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 Gene3D G3DSA:3.50.50.60 11 232 6.0E-13 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 Gene3D G3DSA:3.50.50.60 331 411 6.0E-13 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 9 445 2.9E-208 T 21-04-2016 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 SUPERFAMILY SSF51905 11 378 1.5E-24 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 PANTHER PTHR11806:SF2 9 446 2.9E-242 T 21-04-2016 HSISS4_RS05350 5fd79cd318adab044b103643617ad8f0 447 Gene3D G3DSA:3.50.50.60 290 330 6.1E-8 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 Gene3D G3DSA:3.90.25.10 256 331 9.7E-47 T 21-04-2016 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 Gene3D G3DSA:3.90.25.10 173 224 9.7E-47 T 21-04-2016 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 Gene3D G3DSA:3.40.50.720 1 172 1.7E-51 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 PANTHER PTHR10366 2 332 6.3E-113 T 21-04-2016 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 SUPERFAMILY SSF51735 1 329 8.15E-97 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 254 9.2E-62 T 21-04-2016 IPR001509 NAD-dependent epimerase/dehydratase, N-terminal domain GO:0003824|GO:0050662 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 PANTHER PTHR10366:SF39 2 332 6.3E-113 T 21-04-2016 HSISS4_RS06375 f71062c797a7d7d5e46edaf697291ad7 333 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 328 1.8E-127 T 21-04-2016 IPR005886 UDP-glucose 4-epimerase GalE GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|UniPathway: UPA00214 HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 PANTHER PTHR23513 7 405 1.6E-74 T 21-04-2016 HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 11 374 6.3E-122 T 21-04-2016 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 SUPERFAMILY SSF103473 2 396 1.31E-48 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 Pfam PF07690 Major Facilitator Superfamily 14 362 9.2E-30 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 Gene3D G3DSA:1.20.1250.20 8 195 2.2E-19 T 21-04-2016 HSISS4_RS03085 321fc91dfdad6e5e16848e16873febc0 405 Gene3D G3DSA:1.20.1250.20 209 398 2.9E-16 T 21-04-2016 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 SUPERFAMILY SSF53335 1 178 1.14E-48 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 Pfam PF03602 Conserved hypothetical protein 95 1 177 1.3E-63 T 21-04-2016 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 PANTHER PTHR18895 14 179 3.1E-47 T 21-04-2016 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 PIRSF PIRSF004553 1 179 8.6E-56 T 21-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 Gene3D G3DSA:3.40.50.150 1 179 2.1E-61 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 178 4.2E-52 T 21-04-2016 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 PANTHER PTHR18895:SF60 14 179 3.1E-47 T 21-04-2016 HSISS4_RS07985 af28c91bf7267966d57564bdb03c3f1f 179 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 114 120 - T 21-04-2016 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 46 65 - T 21-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 PANTHER PTHR11938 8 308 7.4E-67 T 21-04-2016 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 PANTHER PTHR11938:SF5 8 308 7.4E-67 T 21-04-2016 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 Gene3D G3DSA:3.20.20.70 6 308 1.6E-87 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 10 307 3.1E-103 T 21-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 SUPERFAMILY SSF51395 8 308 3.66E-77 T 21-04-2016 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 10 311 37.854 T 21-04-2016 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 249 269 - T 21-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 Pfam PF01180 Dihydroorotate dehydrogenase 10 296 1.2E-81 T 21-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HSISS4_RS05065 81162e8b9ec84953d79a5cf959924fd7 318 PIRSF PIRSF000164 1 309 7.6E-77 T 21-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 Hamap MF_00053 Ribonuclease HIII [rnhC]. 1 295 37.452 T 21-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 SUPERFAMILY SSF53098 82 294 5.92E-48 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 PIRSF PIRSF037748 1 296 1.9E-108 T 21-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 Pfam PF01351 Ribonuclease HII 83 288 4.1E-54 T 21-04-2016 IPR024567 Ribonuclease HII/HIII domain HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 PANTHER PTHR10954 12 296 8.9E-85 T 21-04-2016 IPR001352 Ribonuclease HII/HIII GO:0003723|GO:0004523 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 PANTHER PTHR10954:SF12 12 296 8.9E-85 T 21-04-2016 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 Gene3D G3DSA:3.30.420.10 82 246 1.6E-35 T 21-04-2016 IPR012337 Ribonuclease H-like domain GO:0003676 HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 Pfam PF11858 Domain of unknown function (DUF3378) 3 72 6.6E-20 T 21-04-2016 IPR024568 Ribonuclease HIII, N-terminal HSISS4_RS08500 ee4c2cc663b578e5080cc92dc106ef30 296 TIGRFAM TIGR00716 rnhC: ribonuclease HIII 5 287 3.6E-54 T 21-04-2016 IPR004641 Ribonuclease HIII GO:0004523|GO:0005737|GO:0016070 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 Pfam PF00285 Citrate synthase, C-terminal domain 8 357 5.3E-129 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PANTHER PTHR11739:SF4 6 374 1.1E-152 T 21-04-2016 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 Gene3D G3DSA:1.10.230.10 237 321 2.5E-34 T 21-04-2016 IPR016143 Citrate synthase-like, small alpha subdomain HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 SUPERFAMILY SSF48256 6 374 2.75E-130 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PIRSF PIRSF001369 1 374 2.6E-154 T 21-04-2016 IPR024176 Citrate synthase, bacterial-type UniPathway: UPA00223 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 Gene3D G3DSA:1.10.580.10 14 236 2.2E-82 T 21-04-2016 IPR016142 Citrate synthase-like, large alpha subdomain UniPathway: UPA00223 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 ProSitePatterns PS00480 Citrate synthase signature. 257 269 - T 21-04-2016 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 UniPathway: UPA00223 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 307 323 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 175 190 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 197 225 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 327 341 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 250 270 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PRINTS PR00143 Citrate synthase signature 126 139 1.8E-46 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 PANTHER PTHR11739 6 374 1.1E-152 T 21-04-2016 IPR002020 Citrate synthase GO:0046912 HSISS4_RS03695 910c62006c28252e2700e4801b6b285b 374 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 7 374 1.5E-148 T 21-04-2016 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 HSISS4_RS02155 57312aed4d9996755622c60162dbc45c 260 PANTHER PTHR23088 1 259 7.4E-88 T 21-04-2016 HSISS4_RS02155 57312aed4d9996755622c60162dbc45c 260 SUPERFAMILY SSF56317 1 259 8.63E-76 T 21-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HSISS4_RS02155 57312aed4d9996755622c60162dbc45c 260 Pfam PF00795 Carbon-nitrogen hydrolase 2 245 1.4E-49 T 21-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HSISS4_RS02155 57312aed4d9996755622c60162dbc45c 260 Gene3D G3DSA:3.60.110.10 1 260 4.3E-81 T 21-04-2016 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 HSISS4_RS02155 57312aed4d9996755622c60162dbc45c 260 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 140 160 - T 21-04-2016 IPR001110 Uncharacterised protein family UPF0012, conserved site HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 PANTHER PTHR41284 2 71 9.1E-25 T 21-04-2016 HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 Gene3D G3DSA:1.10.150.260 2 71 2.2E-29 T 21-04-2016 IPR023089 YozE SAM-like domain HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 SUPERFAMILY SSF140652 2 71 2.75E-27 T 21-04-2016 IPR023089 YozE SAM-like domain HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 PIRSF PIRSF037262 1 71 4.2E-30 T 21-04-2016 IPR010673 Protein of unknown function UPF0346 HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 Pfam PF06855 YozE SAM-like fold 4 69 6.1E-24 T 21-04-2016 IPR023089 YozE SAM-like domain HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 PANTHER PTHR41284:SF1 2 71 9.1E-25 T 21-04-2016 HSISS4_RS02030 9577fca969cec18fcdcbff74a93b8794 71 Hamap MF_01538 UPF0346 protein . 1 71 22.754 T 21-04-2016 IPR010673 Protein of unknown function UPF0346 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 PANTHER PTHR33164 3 131 5.1E-23 T 21-04-2016 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 Gene3D G3DSA:1.10.10.10 2 133 2.6E-39 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 SMART SM00347 21 123 2.2E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 SUPERFAMILY SSF46785 2 131 3.0E-30 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 Pfam PF12802 MarR family 27 87 1.1E-11 T 21-04-2016 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.2E-6 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.2E-6 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS06665 727bea25d40b14e241f377ce8c19f549 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.2E-6 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 4.0E-27 T 21-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 20 87 7.0E-21 T 21-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 85 6.8E-25 T 21-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 Gene3D G3DSA:1.20.5.440 93 136 5.5E-15 T 21-04-2016 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 SUPERFAMILY SSF51344 3 87 1.57E-21 T 21-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 89 135 1.2E-17 T 21-04-2016 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 PANTHER PTHR13822 1 135 4.9E-29 T 21-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 135 22.329 T 21-04-2016 IPR001469 ATPase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS02275 93d8510a7d71699abbc26cbd1b0c6fd4 138 Gene3D G3DSA:2.60.15.10 3 92 9.8E-24 T 21-04-2016 IPR020546 ATPase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986|GO:0045261|GO:0046933|GO:0046961 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 SMART SM00047 37 193 5.1E-22 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PANTHER PTHR33308 44 193 3.5E-17 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PRINTS PR01002 Flagellar protein FlgJ signature 42 65 1.1E-7 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PRINTS PR01002 Flagellar protein FlgJ signature 66 84 1.1E-7 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PRINTS PR01002 Flagellar protein FlgJ signature 170 188 1.1E-7 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PRINTS PR01002 Flagellar protein FlgJ signature 150 169 1.1E-7 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 SUPERFAMILY SSF53955 40 84 1.74E-5 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 Gene3D G3DSA:1.10.530.10 123 137 7.8E-5 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 Gene3D G3DSA:1.10.530.10 45 80 7.8E-5 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 PANTHER PTHR33308:SF3 44 193 3.5E-17 T 21-04-2016 HSISS4_RS00660 58f342b8e30cb840a4abf153ecb1ab3c 193 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 53 188 9.6E-16 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS09475 d5cb7b86306d8b4e3e48974f0861c067 370 PANTHER PTHR30519 6 369 4.0E-121 T 21-04-2016 HSISS4_RS09475 d5cb7b86306d8b4e3e48974f0861c067 370 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 344 3.9E-13 T 21-04-2016 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702|UniPathway: UPA00051 HSISS4_RS09475 d5cb7b86306d8b4e3e48974f0861c067 370 PANTHER PTHR30519:SF3 6 369 4.0E-121 T 21-04-2016 HSISS4_RS09475 d5cb7b86306d8b4e3e48974f0861c067 370 Gene3D G3DSA:3.20.20.210 5 370 6.6E-111 T 21-04-2016 HSISS4_RS09475 d5cb7b86306d8b4e3e48974f0861c067 370 SUPERFAMILY SSF51726 9 370 6.15E-78 T 21-04-2016 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 205 220 4.4E-13 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 84 99 4.4E-13 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 110 122 4.4E-13 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 72 245 6.3E-49 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 Gene3D G3DSA:2.40.100.10 62 248 2.6E-62 T 21-04-2016 IPR029000 Cyclophilin-like domain HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PANTHER PTHR11071 195 249 9.2E-73 T 21-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PANTHER PTHR11071 1 172 9.2E-73 T 21-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PANTHER PTHR11071:SF282 195 249 9.2E-73 T 21-04-2016 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 PANTHER PTHR11071:SF282 1 172 9.2E-73 T 21-04-2016 HSISS4_RS02405 af37bd5d6d4e07c312851e7acd3ab643 252 SUPERFAMILY SSF50891 71 248 1.75E-53 T 21-04-2016 IPR029000 Cyclophilin-like domain HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 PANTHER PTHR30146 6 333 1.7E-114 T 21-04-2016 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 SMART SM00354 6 76 1.2E-37 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 SUPERFAMILY SSF53822 66 333 5.1E-63 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 Pfam PF13377 Periplasmic binding protein-like domain 182 332 1.1E-20 T 21-04-2016 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 7.1E-22 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 Gene3D G3DSA:1.10.260.40 7 58 1.3E-27 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 PANTHER PTHR30146:SF4 6 333 1.7E-114 T 21-04-2016 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 SUPERFAMILY SSF47413 6 64 1.61E-19 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 Gene3D G3DSA:3.40.50.2300 59 176 5.8E-40 T 21-04-2016 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 Gene3D G3DSA:3.40.50.2300 177 313 1.3E-28 T 21-04-2016 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 6 333 4.9E-160 T 21-04-2016 IPR006377 Catabolite control protein A GO:0006355 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 8.1E-7 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS02965 53a816feb7e52b4f879eab43672dd6ab 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 8.1E-7 T 21-04-2016 IPR000843 Transcription regulator HTH, LacI GO:0003700|GO:0006355 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 PANTHER PTHR11649:SF60 3 436 4.2E-146 T 21-04-2016 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 PIRSF PIRSF006485 2 436 6.4E-170 T 21-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 PANTHER PTHR11649 3 436 4.2E-146 T 21-04-2016 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Hamap MF_00195 GTPase Der [der]. 3 436 39.983 T 21-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 5.4E-33 T 21-04-2016 IPR032859 GTPase Der, C-terminal KH-domain-like HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 178 344 9.6E-25 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 125 7.9E-25 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 SUPERFAMILY SSF52540 138 435 2.41E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 SUPERFAMILY SSF52540 4 168 2.27E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 3.3E-26 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Pfam PF01926 50S ribosome-binding GTPase 177 295 1.1E-24 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 7.9E-174 T 21-04-2016 IPR016484 GTP-binding protein EngA GO:0005525 HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Gene3D G3DSA:3.30.300.20 358 436 5.0E-38 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Gene3D G3DSA:3.40.50.300 2 166 1.5E-43 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01455 2e8b261e05c25b80fbed93292012c184 436 Gene3D G3DSA:3.40.50.300 168 357 2.4E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 PANTHER PTHR24221:SF271 16 594 2.7E-274 T 21-04-2016 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 SUPERFAMILY SSF90123 16 340 1.83E-79 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 Gene3D G3DSA:3.40.50.300 356 586 3.3E-79 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 Gene3D G3DSA:1.20.1560.10 16 340 9.0E-79 T 21-04-2016 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 Pfam PF00664 ABC transporter transmembrane region 29 310 3.4E-49 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 Pfam PF00005 ABC transporter 373 521 8.9E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 PANTHER PTHR24221 16 594 2.7E-274 T 21-04-2016 HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 SUPERFAMILY SSF52540 352 592 3.28E-89 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02525 d68898bec60d6bed2b55cb23080a8458 595 SMART SM00382 381 561 2.1E-15 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01190 96f1860e3125b30865aaae46435cc323 167 SUPERFAMILY SSF109604 16 140 4.28E-20 T 21-04-2016 HSISS4_RS01190 96f1860e3125b30865aaae46435cc323 167 Gene3D G3DSA:1.10.3210.10 12 143 4.1E-28 T 21-04-2016 IPR006674 HD domain HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 14 185 8.0E-89 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 Gene3D G3DSA:3.40.50.10360 4 185 1.5E-80 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 PIRSF PIRSF007510 1 181 2.4E-81 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 Pfam PF04260 Protein of unknown function (DUF436) 10 178 3.8E-70 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 SUPERFAMILY SSF110710 4 185 1.44E-75 T 21-04-2016 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 8 178 6.3E-77 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09180 9300a5d6a5ff63693b5e00230d341cb0 186 Hamap MF_00800 UPF0340 protein . 1 186 92.162 T 21-04-2016 IPR006340 Protein of unknown function DUF436 HSISS4_RS09580 39a8081bc91d743128b9fe86b2fc63e8 120 Pfam PF06993 Protein of unknown function (DUF1304) 11 115 8.0E-33 T 21-04-2016 IPR009732 Protein of unknown function DUF1304 HSISS4_RS09580 39a8081bc91d743128b9fe86b2fc63e8 120 PANTHER PTHR38446:SF1 2 118 3.2E-33 T 21-04-2016 HSISS4_RS09580 39a8081bc91d743128b9fe86b2fc63e8 120 PANTHER PTHR38446 2 118 3.2E-33 T 21-04-2016 HSISS4_RS06460 c99c29933eae4d84067460bd39dcee91 191 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 7 187 2.7E-67 T 21-04-2016 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 KEGG: 00563+2.7.-.- HSISS4_RS06460 c99c29933eae4d84067460bd39dcee91 191 Pfam PF02734 DAK2 domain 30 187 3.4E-48 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS06460 c99c29933eae4d84067460bd39dcee91 191 SMART SM01120 30 188 1.2E-68 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS06460 c99c29933eae4d84067460bd39dcee91 191 SUPERFAMILY SSF101473 2 188 4.45E-57 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS06460 c99c29933eae4d84067460bd39dcee91 191 PANTHER PTHR28629 1 191 2.6E-55 T 21-04-2016 HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 PANTHER PTHR21368 1 152 3.5E-42 T 21-04-2016 IPR000244 Ribosomal protein L9 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 SUPERFAMILY SSF55653 57 149 1.03E-26 T 21-04-2016 IPR020069 Ribosomal protein L9, C-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.525 T 21-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 Gene3D G3DSA:3.40.5.10 1 52 9.6E-22 T 21-04-2016 IPR020070 Ribosomal protein L9, N-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 Gene3D G3DSA:3.10.430.100 61 149 1.2E-30 T 21-04-2016 IPR020069 Ribosomal protein L9, C-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 SUPERFAMILY SSF55658 1 56 4.19E-16 T 21-04-2016 IPR009027 Ribosomal protein L9/RNase H1, N-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 1.7E-41 T 21-04-2016 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 21-04-2016 IPR020070 Ribosomal protein L9, N-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 9.1E-21 T 21-04-2016 IPR020070 Ribosomal protein L9, N-terminal HSISS4_RS09605 203c418db4e4e42a7b6c42f905681a3a 152 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 148 3.6E-28 T 21-04-2016 IPR020069 Ribosomal protein L9, C-terminal HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 Gene3D G3DSA:3.40.190.10 47 128 5.4E-36 T 21-04-2016 HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 Gene3D G3DSA:3.40.190.10 232 269 5.4E-36 T 21-04-2016 HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 SMART SM00062 50 271 5.6E-50 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 PANTHER PTHR18966 49 267 1.4E-25 T 21-04-2016 HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 Gene3D G3DSA:3.40.190.10 129 231 4.0E-24 T 21-04-2016 HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 SUPERFAMILY SSF53850 16 270 2.09E-56 T 21-04-2016 HSISS4_RS04370 b33aa2b72af60990eaada3bb43e36285 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 268 1.7E-47 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 300 2.2E-114 T 21-04-2016 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00240+1.8.1.9|KEGG: 00450+1.8.1.9 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 4.0E-50 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 130 150 - T 21-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 56 66 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 190 206 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 123 135 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 101 109 7.9E-72 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PANTHER PTHR22912:SF48 1 301 5.8E-135 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 Gene3D G3DSA:3.50.50.60 115 235 2.7E-33 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 8.2E-37 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 8.2E-37 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 8.2E-37 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.2E-37 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 8.2E-37 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 PANTHER PTHR22912 1 301 5.8E-135 T 21-04-2016 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 SUPERFAMILY SSF51905 1 298 5.57E-53 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 Gene3D G3DSA:3.50.50.60 1 114 2.8E-45 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07990 1f0e118ccca40f19ac518e8e7d7e8df5 306 Gene3D G3DSA:3.50.50.60 236 300 2.8E-45 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS02490 a1ff80f3bb3511533f2bb75d35f5a1ae 402 Pfam PF02687 FtsX-like permease family 283 395 4.5E-23 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS02490 a1ff80f3bb3511533f2bb75d35f5a1ae 402 PANTHER PTHR30572 1 402 9.5E-85 T 21-04-2016 HSISS4_RS02490 a1ff80f3bb3511533f2bb75d35f5a1ae 402 Pfam PF12704 MacB-like periplasmic core domain 18 242 8.1E-33 T 21-04-2016 IPR025857 MacB-like periplasmic core domain HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 PANTHER PTHR24220 7 276 5.4E-131 T 21-04-2016 HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 Gene3D G3DSA:3.40.50.300 4 267 1.1E-77 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 Pfam PF00005 ABC transporter 26 178 1.7E-29 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 269 6.1E-7 T 21-04-2016 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 SMART SM00382 34 228 5.5E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 SUPERFAMILY SSF52540 5 250 9.53E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06980 15a970360d963555401b3ea8b87c5dbd 309 PANTHER PTHR24220:SF336 7 276 5.4E-131 T 21-04-2016 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 PANTHER PTHR30093 1 74 9.5E-13 T 21-04-2016 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 Pfam PF13633 Prokaryotic N-terminal methylation site 14 38 1.8E-7 T 21-04-2016 IPR012902 Prokaryotic N-terminal methylation site HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 SUPERFAMILY SSF54523 16 102 2.35E-15 T 21-04-2016 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 PANTHER PTHR30093:SF3 1 74 9.5E-13 T 21-04-2016 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 14 34 2.2E-6 T 21-04-2016 IPR012902 Prokaryotic N-terminal methylation site HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 51 69 3.0E-8 T 21-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 PRINTS PR00813 Bacterial general secretion pathway protein G signature 15 40 3.0E-8 T 21-04-2016 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 HSISS4_RS09065 060c551d131d005a403883cbe16f01e6 108 PIRSF PIRSF029928 1 108 2.2E-38 T 21-04-2016 IPR016940 ComG operon protein C GO:0030420 HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 PANTHER PTHR24220 22 265 2.2E-132 T 21-04-2016 HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 Gene3D G3DSA:3.40.50.300 17 257 3.6E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 PANTHER PTHR24220:SF506 22 265 2.2E-132 T 21-04-2016 HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 Pfam PF00005 ABC transporter 37 191 1.1E-30 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 SMART SM00382 45 239 7.1E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 SUPERFAMILY SSF52540 20 253 3.06E-56 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04880 4cde13c5c51f557fcc8449a8f0e0f2f1 267 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 21 267 2.0E-119 T 21-04-2016 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 SUPERFAMILY SSF51569 1 222 2.82E-64 T 21-04-2016 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 Gene3D G3DSA:3.20.20.70 1 223 7.0E-73 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 2 218 8.7E-51 T 21-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 PANTHER PTHR21089:SF5 1 223 5.8E-76 T 21-04-2016 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 222 36.777 T 21-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 PANTHER PTHR21089 1 223 5.8E-76 T 21-04-2016 HSISS4_RS03005 1340e2f5fd820ca7700536518342a602 225 Pfam PF01487 Type I 3-dehydroquinase 5 218 1.5E-54 T 21-04-2016 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|UniPathway: UPA00053 HSISS4_RS00210 738d1d6f338cb48afbf788e109ed9834 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 35 73 1.0E-4 T 21-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HSISS4_RS00210 738d1d6f338cb48afbf788e109ed9834 81 SUPERFAMILY SSF47336 2 79 9.42E-14 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS00210 738d1d6f338cb48afbf788e109ed9834 81 Hamap MF_01217 Acyl carrier protein [acpP]. 5 78 15.302 T 21-04-2016 IPR003231 Acyl carrier protein (ACP) GO:0006633 UniPathway: UPA00094 HSISS4_RS00210 738d1d6f338cb48afbf788e109ed9834 81 Gene3D G3DSA:1.10.1200.10 2 80 4.5E-17 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS00210 738d1d6f338cb48afbf788e109ed9834 81 Pfam PF00550 Phosphopantetheine attachment site 13 74 7.6E-11 T 21-04-2016 IPR009081 Phosphopantetheine binding ACP domain HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 SUPERFAMILY SSF161098 77 276 3.92E-35 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 PANTHER PTHR30614:SF16 5 296 1.3E-65 T 21-04-2016 HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 Gene3D G3DSA:1.10.3720.10 75 290 5.9E-36 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 290 4.8E-16 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 75 185 9.1E-17 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS08005 04c52655c30ccbe7a1b6a03bd6e6eba8 307 PANTHER PTHR30614 5 296 1.3E-65 T 21-04-2016 HSISS4_RS03600 e9125fe4afd1bd14e47d873713a7a693 68 Gene3D G3DSA:1.10.287.760 1 67 1.4E-34 T 21-04-2016 IPR023164 YqgQ-like domain HSISS4_RS03600 e9125fe4afd1bd14e47d873713a7a693 68 SUPERFAMILY SSF158379 1 62 1.7E-25 T 21-04-2016 IPR023164 YqgQ-like domain HSISS4_RS03600 e9125fe4afd1bd14e47d873713a7a693 68 PANTHER PTHR41311 1 68 6.2E-20 T 21-04-2016 HSISS4_RS03600 e9125fe4afd1bd14e47d873713a7a693 68 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 61 5.7E-31 T 21-04-2016 IPR009256 Protein of unknown function DUF910 HSISS4_RS02220 bc11af5019bc08776a2ea2224bdbf5e7 186 Pfam PF13302 Acetyltransferase (GNAT) domain 14 155 1.5E-29 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS02220 bc11af5019bc08776a2ea2224bdbf5e7 186 PANTHER PTHR13256 1 186 2.7E-54 T 21-04-2016 HSISS4_RS02220 bc11af5019bc08776a2ea2224bdbf5e7 186 Gene3D G3DSA:3.40.630.30 7 185 5.9E-50 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02220 bc11af5019bc08776a2ea2224bdbf5e7 186 SUPERFAMILY SSF55729 8 180 5.41E-44 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02220 bc11af5019bc08776a2ea2224bdbf5e7 186 PANTHER PTHR13256:SF10 1 186 2.7E-54 T 21-04-2016 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 Gene3D G3DSA:3.40.50.300 133 306 5.5E-70 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 4.6E-73 T 21-04-2016 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 PANTHER PTHR30305:SF1 1 309 6.5E-128 T 21-04-2016 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 Pfam PF02603 HPr Serine kinase N terminus 3 127 1.3E-37 T 21-04-2016 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 Gene3D G3DSA:3.40.1390.20 3 131 8.9E-44 T 21-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 2 306 40.768 T 21-04-2016 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 PANTHER PTHR30305 1 309 6.5E-128 T 21-04-2016 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 SUPERFAMILY SSF53795 132 298 1.07E-38 T 21-04-2016 HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 SUPERFAMILY SSF75138 3 131 4.32E-38 T 21-04-2016 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like HSISS4_RS03330 8cb63995bb96bc345b5aa5e0066554c4 309 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 3 301 8.7E-109 T 21-04-2016 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 HSISS4_RS06250 ae04959354daf0fa34efeace776fea8a 381 Pfam PF02687 FtsX-like permease family 65 177 4.6E-11 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS06250 ae04959354daf0fa34efeace776fea8a 381 Pfam PF02687 FtsX-like permease family 256 371 9.6E-8 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS00490 f66dc74bc11e6ffcae122419d82ff084 151 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 4 145 1.1E-49 T 21-04-2016 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 HSISS4_RS00490 f66dc74bc11e6ffcae122419d82ff084 151 PANTHER PTHR40028 1 149 5.3E-59 T 21-04-2016 HSISS4_RS00490 f66dc74bc11e6ffcae122419d82ff084 151 PANTHER PTHR40028:SF1 1 149 5.3E-59 T 21-04-2016 HSISS4_RS00490 f66dc74bc11e6ffcae122419d82ff084 151 PIRSF PIRSF010607 1 150 5.2E-61 T 21-04-2016 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355|GO:0006950 HSISS4_RS08035 fe7c859b241dfe0df9eca2097de813ae 150 Gene3D G3DSA:3.40.630.30 3 143 5.7E-35 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS08035 fe7c859b241dfe0df9eca2097de813ae 150 PANTHER PTHR13355 5 145 1.7E-26 T 21-04-2016 HSISS4_RS08035 fe7c859b241dfe0df9eca2097de813ae 150 SUPERFAMILY SSF55729 2 145 6.75E-34 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS08035 fe7c859b241dfe0df9eca2097de813ae 150 Pfam PF13673 Acetyltransferase (GNAT) domain 45 144 2.9E-18 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS08035 fe7c859b241dfe0df9eca2097de813ae 150 PANTHER PTHR13355:SF8 5 145 1.7E-26 T 21-04-2016 HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 PANTHER PTHR24220 5 207 1.8E-60 T 21-04-2016 HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 Pfam PF00005 ABC transporter 19 165 1.5E-25 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 SUPERFAMILY SSF52540 3 215 5.42E-50 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 SMART SM00382 28 215 1.7E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00905 057dd1363907471b334f3b511fda9e7f 235 Gene3D G3DSA:3.40.50.300 3 213 2.5E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PANTHER PTHR11777:SF9 1 870 0.0 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 6.8E-30 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 6.8E-30 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 6.8E-30 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 278 294 6.8E-30 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PRINTS PR00980 Alanyl-tRNA synthetase signature 302 315 6.8E-30 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 855 1.1E-291 T 21-04-2016 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 SUPERFAMILY SSF55186 555 707 4.45E-52 T 21-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Gene3D G3DSA:3.30.930.10 4 244 2.9E-87 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Gene3D G3DSA:3.30.980.10 566 624 5.6E-5 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Gene3D G3DSA:3.30.980.10 675 685 5.6E-5 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 656 698 1.9E-20 T 21-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 PANTHER PTHR11777 1 870 0.0 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 SUPERFAMILY SSF101353 249 442 1.28E-65 T 21-04-2016 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7|Reactome: REACT_71 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 SUPERFAMILY SSF55681 5 248 7.7E-80 T 21-04-2016 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Pfam PF02272 DHHA1 domain 804 869 7.1E-11 T 21-04-2016 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 872 170.692 T 21-04-2016 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 Pfam PF01411 tRNA synthetases class II (A) 8 558 4.2E-185 T 21-04-2016 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 SUPERFAMILY SSF50447 460 554 2.01E-13 T 21-04-2016 IPR009000 Translation protein, beta-barrel domain HSISS4_RS02115 90a92949bffaeb75a1c1cb378846d6ba 872 SMART SM00863 656 699 2.7E-22 T 21-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 PANTHER PTHR11560 1 163 2.6E-54 T 21-04-2016 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 ProSitePatterns PS01109 Ribosomal protein L10 signature. 9 43 - T 21-04-2016 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 20 145 3.0E-4 T 21-04-2016 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 4 162 27.599 T 21-04-2016 IPR022973 Ribosomal protein L10 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 Pfam PF00466 Ribosomal protein L10 7 102 8.8E-27 T 21-04-2016 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 HSISS4_RS02495 292a12fe657697c43faf75c334191f7b 167 SUPERFAMILY SSF160369 6 161 3.79E-51 T 21-04-2016 HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 Gene3D G3DSA:3.10.200.10 40 259 1.3E-72 T 21-04-2016 IPR001148 Alpha carbonic anhydrase HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 PANTHER PTHR18952 38 260 1.0E-71 T 21-04-2016 IPR023561 Carbonic anhydrase, alpha-class HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 ProSitePatterns PS00162 Alpha-carbonic anhydrases signature. 131 147 - T 21-04-2016 IPR018338 Carbonic anhydrase, alpha-class, conserved site GO:0004089|GO:0006730|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 SMART SM01057 41 260 7.6E-91 T 21-04-2016 IPR001148 Alpha carbonic anhydrase HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 Pfam PF00194 Eukaryotic-type carbonic anhydrase 40 260 2.7E-47 T 21-04-2016 IPR001148 Alpha carbonic anhydrase HSISS4_RS08030 052d11a3c1142282eac16aed3b323609 261 SUPERFAMILY SSF51069 40 259 1.96E-75 T 21-04-2016 IPR001148 Alpha carbonic anhydrase HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 Gene3D G3DSA:3.90.70.10 51 443 1.6E-173 T 21-04-2016 HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 PIRSF PIRSF005700 1 444 1.3E-176 T 21-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 63 74 - T 21-04-2016 IPR000169 Cysteine peptidase, cysteine active site HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 Pfam PF03051 Peptidase C1-like family 4 440 1.9E-210 T 21-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 SUPERFAMILY SSF54001 7 443 1.02E-128 T 21-04-2016 HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 361 371 - T 21-04-2016 IPR025660 Cysteine peptidase, histidine active site HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 PANTHER PTHR10363:SF4 4 444 1.3E-266 T 21-04-2016 HSISS4_RS01105 44523ad113feb746f4dea7ad6bc43e79 445 PANTHER PTHR10363 4 444 1.3E-266 T 21-04-2016 IPR004134 Peptidase C1B, bleomycin hydrolase GO:0004197|GO:0006508 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 Gene3D G3DSA:3.20.20.70 3 341 1.3E-106 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 PIRSF PIRSF001361 1 342 6.0E-115 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 PANTHER PTHR21225 3 341 3.0E-155 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 Pfam PF00793 DAHP synthetase I family 33 332 1.6E-52 T 21-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 7 341 3.0E-81 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS08325 ae9e4a6331cc10e28f4c1f967bada0c8 342 SUPERFAMILY SSF51569 2 340 3.91E-95 T 21-04-2016 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 PANTHER PTHR24221:SF258 9 580 3.5E-232 T 21-04-2016 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 Pfam PF00664 ABC transporter transmembrane region 25 294 8.7E-39 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 Pfam PF00005 ABC transporter 356 504 6.6E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 SUPERFAMILY SSF90123 11 321 4.58E-70 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 Gene3D G3DSA:1.20.1560.10 10 321 2.4E-73 T 21-04-2016 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 PANTHER PTHR24221 9 580 3.5E-232 T 21-04-2016 HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 Gene3D G3DSA:3.40.50.300 339 568 1.6E-77 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 SUPERFAMILY SSF52540 334 574 2.45E-87 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08090 960ac8f6386e2e21e6288636bba4844c 581 SMART SM00382 365 556 1.3E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 SUPERFAMILY SSF56194 192 296 4.97E-36 T 21-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Gene3D G3DSA:3.90.78.10 224 297 1.9E-31 T 21-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Gene3D G3DSA:3.30.43.10 1 85 1.6E-32 T 21-04-2016 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 PANTHER PTHR21071 1 300 3.0E-127 T 21-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Gene3D G3DSA:3.30.465.10 86 223 4.4E-49 T 21-04-2016 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 20 296 1.6E-70 T 21-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Pfam PF01565 FAD binding domain 33 161 6.0E-27 T 21-04-2016 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 300 96.838 T 21-04-2016 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 SUPERFAMILY SSF56176 2 191 7.63E-49 T 21-04-2016 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 PANTHER PTHR21071:SF4 1 300 3.0E-127 T 21-04-2016 HSISS4_RS07355 feb6c6be188eb959ae206a3206b98717 300 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 196 295 2.7E-27 T 21-04-2016 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 1.2E-16 T 21-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 1.2E-16 T 21-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 1.2E-16 T 21-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 21-04-2016 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.699 T 21-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 Pfam PF01632 Ribosomal protein L35 2 62 7.9E-21 T 21-04-2016 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 SUPERFAMILY SSF143034 2 62 1.44E-19 T 21-04-2016 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 PANTHER PTHR33343 1 62 7.5E-22 T 21-04-2016 HSISS4_RS04505 ce2fbaf33381533f1b198c8ece152a6d 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 9.6E-22 T 21-04-2016 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 Pfam PF01545 Cation efflux family 15 206 6.3E-46 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 Gene3D G3DSA:1.20.1510.10 14 205 5.5E-42 T 21-04-2016 IPR027469 Cation efflux protein transmembrane domain HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 287 8.1E-60 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 PANTHER PTHR11562:SF18 8 296 2.8E-71 T 21-04-2016 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 Gene3D G3DSA:3.30.70.1350 208 287 1.4E-23 T 21-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 SUPERFAMILY SSF160240 210 287 1.15E-17 T 21-04-2016 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 SUPERFAMILY SSF161111 7 208 4.05E-49 T 21-04-2016 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 PANTHER PTHR11562 8 296 2.8E-71 T 21-04-2016 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 HSISS4_RS04720 3dfb81cfc519da36f5f60c23dbda5f82 398 Pfam PF16916 Dimerisation domain of Zinc Transporter 212 287 7.3E-17 T 21-04-2016 IPR027470 Cation efflux protein, cytoplasmic domain HSISS4_RS09015 46d6fca1c602ef80048d47bd43b21360 220 PANTHER PTHR36435:SF1 5 212 5.7E-15 T 21-04-2016 HSISS4_RS09015 46d6fca1c602ef80048d47bd43b21360 220 Pfam PF02517 CAAX protease self-immunity 115 203 1.0E-19 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS09015 46d6fca1c602ef80048d47bd43b21360 220 PANTHER PTHR36435 5 212 5.7E-15 T 21-04-2016 HSISS4_RS01500 9693740d4046507cf1dc7c96da325199 266 PANTHER PTHR32502:SF10 1 264 6.5E-112 T 21-04-2016 HSISS4_RS01500 9693740d4046507cf1dc7c96da325199 266 PANTHER PTHR32502 1 264 6.5E-112 T 21-04-2016 HSISS4_RS01500 9693740d4046507cf1dc7c96da325199 266 Pfam PF03609 PTS system sorbose-specific iic component 3 236 3.7E-69 T 21-04-2016 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 HSISS4_RS05495 a384d35a361f5231b41758be60538d15 237 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 57 190 2.2E-19 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS05495 a384d35a361f5231b41758be60538d15 237 PANTHER PTHR33308:SF3 40 196 5.8E-22 T 21-04-2016 HSISS4_RS05495 a384d35a361f5231b41758be60538d15 237 PANTHER PTHR33308 40 196 5.8E-22 T 21-04-2016 HSISS4_RS05495 a384d35a361f5231b41758be60538d15 237 SMART SM00047 41 195 4.0E-38 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 Gene3D G3DSA:3.40.50.1860 2 172 1.7E-56 T 21-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 TIGRFAM TIGR00067 glut_race: glutamate racemase 6 254 3.4E-74 T 21-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 21-04-2016 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 70 78 - T 21-04-2016 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 SUPERFAMILY SSF53681 109 261 8.11E-40 T 21-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 SUPERFAMILY SSF53681 5 106 1.21E-34 T 21-04-2016 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 PANTHER PTHR21198 1 264 1.7E-110 T 21-04-2016 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 PANTHER PTHR21198:SF2 1 264 1.7E-110 T 21-04-2016 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 213 9.6E-37 T 21-04-2016 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS01220 6066793875447a9eb9c252b554d202a1 271 Hamap MF_00258 Glutamate racemase [murI]. 4 256 39.73 T 21-04-2016 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 Gene3D G3DSA:1.20.1250.20 216 384 3.2E-12 T 21-04-2016 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 Gene3D G3DSA:1.20.1250.20 13 194 6.5E-17 T 21-04-2016 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 PANTHER PTHR23530 1 397 4.2E-30 T 21-04-2016 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 Pfam PF07690 Major Facilitator Superfamily 17 321 2.1E-16 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 PANTHER PTHR23530:SF1 1 397 4.2E-30 T 21-04-2016 HSISS4_RS05580 53cc7825447f45d560941ca8928719a7 399 SUPERFAMILY SSF103473 14 388 1.44E-35 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 Pfam PF00155 Aminotransferase class I and II 34 379 5.3E-61 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 PANTHER PTHR11751:SF417 14 390 2.6E-164 T 21-04-2016 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 Gene3D G3DSA:3.90.1150.10 255 387 3.2E-41 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 21-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 PANTHER PTHR11751 14 390 2.6E-164 T 21-04-2016 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 Gene3D G3DSA:3.40.640.10 44 254 1.0E-67 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS00195 d86495a7daf5f0feb257b45a9e91e5a8 391 SUPERFAMILY SSF53383 6 387 4.65E-107 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 PANTHER PTHR10108:SF927 1 275 1.2E-86 T 21-04-2016 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 SUPERFAMILY SSF53335 70 276 1.08E-30 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 TIGRFAM TIGR00477 tehB: tellurite resistance protein TehB 50 290 1.7E-103 T 21-04-2016 IPR004537 Tellurite resistance methyltransferase, TehB GO:0005737|GO:0008757|GO:0046690 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 Gene3D G3DSA:3.40.50.150 105 290 1.7E-32 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 Pfam PF09313 Domain of unknown function (DUF1971) 11 91 1.1E-29 T 21-04-2016 IPR015392 Domain of unknown function DUF1971 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 PIRSF PIRSF005215 1 292 2.8E-136 T 21-04-2016 IPR014431 Tellurite resistance methyltransferase, TehB type-2 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 PANTHER PTHR10108 1 275 1.2E-86 T 21-04-2016 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 SUPERFAMILY SSF51197 2 104 1.0E-36 T 21-04-2016 HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 Pfam PF03848 Tellurite resistance protein TehB 93 287 3.4E-83 T 21-04-2016 IPR015985 Tellurite resistance methyltransferase TehB-like domain HSISS4_RS07425 67cd18f2826acbf18a6968806ae79f3a 292 Gene3D G3DSA:2.60.120.10 2 104 4.6E-49 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PANTHER PTHR11706 1 444 1.1E-162 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PANTHER PTHR11706:SF33 1 444 1.1E-162 T 21-04-2016 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 Pfam PF01566 Natural resistance-associated macrophage protein 48 418 1.1E-110 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 19 444 34.875 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 217 240 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 326 345 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 388 407 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 107 133 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 135 154 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 PRINTS PR00447 Natural resistance-associated macrophage protein signature 354 371 3.5E-54 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS03385 cde14cc70e0e6067f0d940f59f58ae31 444 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 27 412 7.3E-106 T 21-04-2016 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: REACT_15518 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 Pfam PF00484 Carbonic anhydrase 32 159 6.5E-14 T 21-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 Gene3D G3DSA:3.40.1050.10 3 163 9.4E-41 T 21-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 SMART SM00947 24 164 1.5E-31 T 21-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 SUPERFAMILY SSF53056 4 163 1.83E-41 T 21-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 PANTHER PTHR11002:SF9 1 163 5.3E-61 T 21-04-2016 HSISS4_RS08860 4b463665e6e0121a54f56d4752780130 165 PANTHER PTHR11002 1 163 5.3E-61 T 21-04-2016 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PANTHER PTHR30511 3 366 6.7E-145 T 21-04-2016 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 SUPERFAMILY SSF51419 13 243 3.01E-64 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 Gene3D G3DSA:3.20.20.10 15 221 1.3E-69 T 21-04-2016 IPR029066 PLP-binding barrel HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 TIGRFAM TIGR00492 alr: alanine racemase 8 366 2.1E-109 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 SMART SM01005 242 367 8.7E-68 T 21-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 127 139 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 258 273 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 349 362 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 67 85 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 32 48 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 161 172 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 201 228 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 275 290 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PRINTS PR00992 Alanine racemase signature 295 312 6.8E-70 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 PANTHER PTHR30511:SF0 3 366 6.7E-145 T 21-04-2016 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 SUPERFAMILY SSF50621 237 366 1.01E-49 T 21-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 Gene3D G3DSA:2.40.37.10 222 366 1.6E-55 T 21-04-2016 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 Reactome: REACT_13 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 21-04-2016 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 Pfam PF01168 Alanine racemase, N-terminal domain 13 228 1.9E-65 T 21-04-2016 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 Hamap MF_01201 Alanine racemase. 6 367 35.147 T 21-04-2016 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08315 21fcba632090cfbfb71826c542d8a7f4 367 Pfam PF00842 Alanine racemase, C-terminal domain 242 366 1.3E-39 T 21-04-2016 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383|UniPathway: UPA00042 HSISS4_RS08205 339bd6bb31131f42362635006ce317ad 243 PANTHER PTHR36111:SF1 4 239 1.2E-60 T 21-04-2016 HSISS4_RS08205 339bd6bb31131f42362635006ce317ad 243 PANTHER PTHR36111 4 239 1.2E-60 T 21-04-2016 HSISS4_RS08205 339bd6bb31131f42362635006ce317ad 243 Pfam PF04474 Protein of unknown function (DUF554) 3 232 1.3E-63 T 21-04-2016 IPR007563 Protein of unknown function DUF554 HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 SUPERFAMILY SSF54001 98 208 6.28E-23 T 21-04-2016 HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 SMART SM00257 30 74 6.1E-6 T 21-04-2016 IPR018392 LysM domain HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 Pfam PF01476 LysM domain 31 59 3.9E-5 T 21-04-2016 IPR018392 LysM domain HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 128 152 1.2E-30 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 171 194 1.2E-30 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 103 125 1.2E-30 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 2 29 1.2E-30 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 Pfam PF05257 CHAP domain 101 178 6.6E-13 T 21-04-2016 IPR007921 CHAP domain HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 SUPERFAMILY SSF54106 29 73 2.49E-8 T 21-04-2016 IPR018392 LysM domain HSISS4_RS08550 2606dea6aeccb30e49b988ecaccb05b7 210 Gene3D G3DSA:3.10.350.10 28 73 3.3E-11 T 21-04-2016 IPR018392 LysM domain HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 PANTHER PTHR24221 2 577 9.5E-272 T 21-04-2016 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 SUPERFAMILY SSF90123 11 324 3.79E-65 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 Gene3D G3DSA:1.20.1560.10 11 326 1.0E-63 T 21-04-2016 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 PANTHER PTHR24221:SF271 2 577 9.5E-272 T 21-04-2016 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 Gene3D G3DSA:3.40.50.300 342 573 1.3E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 Pfam PF00005 ABC transporter 359 507 3.2E-33 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 SUPERFAMILY SSF52540 336 577 2.33E-87 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 Pfam PF00664 ABC transporter transmembrane region 25 295 1.3E-40 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 ProSitePatterns PS00211 ABC transporters family signature. 479 493 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05765 f40c433ea8898b7a0c79405b21a68526 582 SMART SM00382 367 553 4.2E-15 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 Gene3D G3DSA:3.40.309.10 265 444 2.0E-61 T 21-04-2016 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0008152|GO:0016491|GO:0016620|GO:0055114 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 21-04-2016 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 PANTHER PTHR11699:SF160 4 474 1.3E-287 T 21-04-2016 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 SUPERFAMILY SSF53720 3 471 6.28E-143 T 21-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 PANTHER PTHR11699 4 474 1.3E-287 T 21-04-2016 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 21-04-2016 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 Pfam PF00171 Aldehyde dehydrogenase family 14 469 1.7E-148 T 21-04-2016 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS03715 3210dc7262f22b3f29d95f34e48e810b 477 Gene3D G3DSA:3.40.605.10 4 264 1.5E-87 T 21-04-2016 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Gene3D G3DSA:1.10.150.20 7 34 2.8E-4 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SUPERFAMILY SSF52540 274 327 3.44E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Gene3D G3DSA:2.40.50.140 44 121 5.7E-19 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Gene3D G3DSA:3.40.50.300 243 433 5.7E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Pfam PF00271 Helicase conserved C-terminal domain 458 567 4.2E-20 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031 284 581 1.3E-122 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031 240 267 1.3E-122 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031 604 649 1.3E-122 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SUPERFAMILY SSF52540 171 431 4.57E-61 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SMART SM00487 250 438 7.9E-31 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SMART SM00490 483 568 1.2E-23 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 642 1.8E-241 T 21-04-2016 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Pfam PF00270 DEAD/DEAH box helicase 255 410 2.4E-16 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SUPERFAMILY SSF50249 2 162 5.65E-31 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Pfam PF17191 RecG wedge domain 11 158 4.4E-15 T 21-04-2016 IPR033454 RecG, wedge domain HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 Gene3D G3DSA:3.40.50.300 434 616 9.3E-46 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 SUPERFAMILY SSF52540 486 631 3.44E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031:SF249 284 581 1.3E-122 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031:SF249 240 267 1.3E-122 T 21-04-2016 HSISS4_RS08310 288c7b7435ff2ab6401037472b154e55 672 PANTHER PTHR24031:SF249 604 649 1.3E-122 T 21-04-2016 HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 SUPERFAMILY SSF56281 1 309 4.32E-77 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 Gene3D G3DSA:3.60.15.10 3 309 2.3E-79 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 Pfam PF00753 Metallo-beta-lactamase superfamily 31 104 2.2E-10 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 PANTHER PTHR12553 187 309 1.4E-81 T 21-04-2016 HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 PANTHER PTHR12553 1 156 1.4E-81 T 21-04-2016 HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 309 4.6E-106 T 21-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 HSISS4_RS04010 34fb2138072653dc0da0e111032efb89 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 309 38.546 T 21-04-2016 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 SUPERFAMILY SSF161098 14 276 1.44E-38 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 Gene3D G3DSA:1.10.3720.10 57 287 2.5E-43 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 292 1.2E-35 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 7 284 7.1E-79 T 21-04-2016 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 PANTHER PTHR30425 1 294 2.8E-113 T 21-04-2016 HSISS4_RS04885 094606cd52e89b96e3535d83aa5d78e1 294 PANTHER PTHR30425:SF0 1 294 2.8E-113 T 21-04-2016 HSISS4_RS05650 e959697375fcc59566c717687fb4470b 196 SUPERFAMILY SSF53335 23 192 1.26E-41 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS05650 e959697375fcc59566c717687fb4470b 196 Gene3D G3DSA:3.40.50.150 26 188 3.3E-38 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS05650 e959697375fcc59566c717687fb4470b 196 PANTHER PTHR18895 1 194 3.1E-87 T 21-04-2016 HSISS4_RS05650 e959697375fcc59566c717687fb4470b 196 Pfam PF05175 Methyltransferase small domain 28 192 7.3E-53 T 21-04-2016 IPR007848 Methyltransferase small domain GO:0008168 HSISS4_RS05650 e959697375fcc59566c717687fb4470b 196 PANTHER PTHR18895:SF72 1 194 3.1E-87 T 21-04-2016 HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 2 187 1.0E-50 T 21-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 SUPERFAMILY SSF52540 1 191 9.19E-36 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 Gene3D G3DSA:3.40.50.300 1 195 6.5E-67 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 PANTHER PTHR10695 2 196 3.7E-66 T 21-04-2016 HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 23.352 T 21-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HSISS4_RS02925 db2f10a0eb3bcd83576b3af899356b68 197 Pfam PF01121 Dephospho-CoA kinase 1 180 2.1E-47 T 21-04-2016 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|UniPathway: UPA00241 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 PANTHER PTHR32039:SF8 72 278 7.8E-89 T 21-04-2016 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 Pfam PF02481 DNA recombination-mediator protein A 71 269 1.3E-77 T 21-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 PANTHER PTHR32039 72 278 7.8E-89 T 21-04-2016 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 SUPERFAMILY SSF102405 74 274 6.41E-35 T 21-04-2016 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 Gene3D G3DSA:3.40.50.450 105 248 1.2E-7 T 21-04-2016 HSISS4_RS05385 6adb367f43258ccba8c85aec1a716968 279 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 73 277 6.6E-74 T 21-04-2016 IPR003488 DNA recombination-mediator protein A GO:0009294 HSISS4_RS06300 0c04592aeb4674f74cf6ae1e982122e6 287 SUPERFAMILY SSF53474 113 262 2.31E-8 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS06300 0c04592aeb4674f74cf6ae1e982122e6 287 SUPERFAMILY SSF53474 45 74 2.31E-8 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS06300 0c04592aeb4674f74cf6ae1e982122e6 287 Gene3D G3DSA:3.40.50.1820 40 271 6.0E-70 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS06300 0c04592aeb4674f74cf6ae1e982122e6 287 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 40 273 1.6E-60 T 21-04-2016 IPR010315 Protein of unknown function DUF915, hydrolase-like HSISS4_RS03980 c568a5304661600acd1b20327b36247f 179 Gene3D G3DSA:1.10.340.30 14 174 3.2E-66 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS03980 c568a5304661600acd1b20327b36247f 179 PANTHER PTHR30037:SF4 14 173 4.1E-88 T 21-04-2016 HSISS4_RS03980 c568a5304661600acd1b20327b36247f 179 PANTHER PTHR30037 14 173 4.1E-88 T 21-04-2016 HSISS4_RS03980 c568a5304661600acd1b20327b36247f 179 SUPERFAMILY SSF48150 13 174 2.67E-64 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS03980 c568a5304661600acd1b20327b36247f 179 Pfam PF03352 Methyladenine glycosylase 14 173 1.1E-65 T 21-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 PANTHER PTHR33434 1 555 8.4E-251 T 21-04-2016 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 Pfam PF13684 Dihydroxyacetone kinase family 240 555 2.5E-128 T 21-04-2016 IPR033470 Uncharacterised protein, DhaK domain HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 SUPERFAMILY SSF101473 3 200 2.35E-47 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 SMART SM01121 240 555 2.1E-194 T 21-04-2016 IPR033470 Uncharacterised protein, DhaK domain HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 PANTHER PTHR33434:SF4 1 555 8.4E-251 T 21-04-2016 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 Pfam PF02734 DAK2 domain 34 198 3.4E-41 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 SMART SM01120 34 199 2.8E-69 T 21-04-2016 IPR004007 DhaL domain GO:0004371|GO:0006071 HSISS4_RS09125 b479d7f0f0ef95d6e58ff47cd1acf3a1 555 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 9 555 5.0E-214 T 21-04-2016 IPR019986 DAK2 domain-containing protein YloV HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 8.2E-12 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 Gene3D G3DSA:1.10.10.10 3 76 7.5E-23 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 SUPERFAMILY SSF46785 5 78 5.75E-18 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 PANTHER PTHR38445 1 120 2.9E-17 T 21-04-2016 HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 SMART SM00345 15 74 7.2E-12 T 21-04-2016 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 HSISS4_RS06965 b0da85f174d5765fd5f8406b2e3cbf78 125 PANTHER PTHR38445:SF2 1 120 2.9E-17 T 21-04-2016 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 21-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 PANTHER PTHR11758 1 132 3.1E-68 T 21-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.187 T 21-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 Gene3D G3DSA:3.30.1490.10 76 132 5.8E-30 T 21-04-2016 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 Gene3D G3DSA:3.30.1370.30 2 73 1.2E-30 T 21-04-2016 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 Pfam PF00410 Ribosomal protein S8 5 132 1.6E-53 T 21-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09280 a2f81354925bbbfe26c4988ba0079729 132 SUPERFAMILY SSF56047 2 132 1.57E-49 T 21-04-2016 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 273 5.0E-55 T 21-04-2016 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 252 3.7E-23 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 ProSitePatterns PS00727 AP endonucleases family 1 signature 2. 207 223 - T 21-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 234 245 - T 21-04-2016 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 37 46 - T 21-04-2016 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 PANTHER PTHR22748 1 275 2.4E-87 T 21-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 Gene3D G3DSA:3.60.10.10 1 274 1.4E-75 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 SUPERFAMILY SSF56219 1 275 2.75E-57 T 21-04-2016 IPR005135 Endonuclease/exonuclease/phosphatase HSISS4_RS07445 267329639b48ee2c4b3c97ce87a95425 275 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 274 1.9E-83 T 21-04-2016 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 SUPERFAMILY SSF47005 165 204 8.76E-11 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Gene3D G3DSA:4.10.320.10 121 166 2.9E-18 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Gene3D G3DSA:4.10.320.10 167 208 4.6E-17 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Pfam PF02817 e3 binding domain 167 202 2.9E-14 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Pfam PF02817 e3 binding domain 125 160 1.2E-12 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 PANTHER PTHR23151 213 461 6.2E-141 T 21-04-2016 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 PANTHER PTHR23151 4 168 6.2E-141 T 21-04-2016 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 SUPERFAMILY SSF52777 223 462 7.12E-77 T 21-04-2016 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 231 461 8.0E-76 T 21-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Gene3D G3DSA:3.30.559.10 221 461 3.7E-79 T 21-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 SUPERFAMILY SSF47005 118 162 3.27E-12 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Pfam PF00364 Biotin-requiring enzyme 4 76 1.2E-18 T 21-04-2016 IPR000089 Biotin/lipoyl attachment HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 SUPERFAMILY SSF51230 1 92 1.44E-25 T 21-04-2016 IPR011053 Single hybrid motif HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 21-04-2016 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site HSISS4_RS04760 7da7146e1337b3b5400569f28091c927 462 Gene3D G3DSA:2.40.50.100 1 95 8.6E-28 T 21-04-2016 HSISS4_RS03200 54e4769025ed44857d91db200106c330 229 SUPERFAMILY SSF53474 12 225 1.05E-36 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03200 54e4769025ed44857d91db200106c330 229 Pfam PF00756 Putative esterase 12 210 4.6E-8 T 21-04-2016 IPR000801 Putative esterase HSISS4_RS03200 54e4769025ed44857d91db200106c330 229 Gene3D G3DSA:3.40.50.1820 12 228 2.2E-22 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 78 16.062 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 76 5.0E-18 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 77 1.3E-20 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 Pfam PF01649 Ribosomal protein S20 2 76 2.5E-21 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 PANTHER PTHR33398 2 78 3.3E-24 T 21-04-2016 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 SUPERFAMILY SSF46992 3 76 9.94E-23 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS05660 fd6836b31ceb988a92a2697469a62dfd 78 Gene3D G3DSA:1.20.58.110 1 77 2.1E-22 T 21-04-2016 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS06110 9324d466798bb2b366b45868df38db06 245 PANTHER PTHR30294 1 244 6.4E-43 T 21-04-2016 HSISS4_RS06110 9324d466798bb2b366b45868df38db06 245 PIRSF PIRSF006648 3 242 5.7E-19 T 21-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HSISS4_RS06110 9324d466798bb2b366b45868df38db06 245 Pfam PF01061 ABC-2 type transporter 2 206 3.3E-14 T 21-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HSISS4_RS06110 9324d466798bb2b366b45868df38db06 245 PANTHER PTHR30294:SF6 1 244 6.4E-43 T 21-04-2016 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 SUPERFAMILY SSF52540 292 522 1.74E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 SMART SM00382 321 505 3.4E-12 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 SMART SM00382 31 223 4.9E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 Pfam PF12558 ATP-binding cassette cobalt transporter 237 302 1.0E-10 T 21-04-2016 IPR022216 ABC cobalt transporter GO:0016820 KEGG: 00920+3.6.3.- HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 Gene3D G3DSA:3.40.50.300 2 236 2.8E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 SUPERFAMILY SSF52540 4 236 1.94E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 PANTHER PTHR24220:SF588 285 417 1.3E-190 T 21-04-2016 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 PANTHER PTHR24220:SF588 6 250 1.3E-190 T 21-04-2016 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 Pfam PF00005 ABC transporter 313 457 4.0E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 Pfam PF00005 ABC transporter 22 172 6.1E-28 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 PANTHER PTHR24220 285 417 1.3E-190 T 21-04-2016 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 PANTHER PTHR24220 6 250 1.3E-190 T 21-04-2016 HSISS4_RS01400 bc88def26151f2d0124ba092f3ae363e 558 Gene3D G3DSA:3.40.50.300 286 529 1.2E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 56 122 2.0E-28 T 21-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 57 94 1.0E-13 T 21-04-2016 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 Gene3D G3DSA:1.20.5.710 2 52 1.2E-20 T 21-04-2016 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 52 1.4E-18 T 21-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 122 23.703 T 21-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 122 3.4E-43 T 21-04-2016 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 SUPERFAMILY SSF54736 53 122 1.69E-22 T 21-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 Gene3D G3DSA:3.30.1390.10 53 122 4.3E-30 T 21-04-2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like HSISS4_RS02500 5ed76ecdc50a5785b030f8a2976baf72 122 SUPERFAMILY SSF48300 3 50 9.68E-14 T 21-04-2016 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PANTHER PTHR10353 7 479 2.7E-283 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 Gene3D G3DSA:3.20.20.80 5 477 5.1E-148 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PANTHER PTHR10353:SF74 7 479 2.7E-283 T 21-04-2016 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 1.4E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 372 380 1.4E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 306 320 1.4E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 393 404 1.4E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 PRINTS PR00131 Glycosyl hydrolase family 1 signature 415 432 1.4E-16 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 SUPERFAMILY SSF51445 5 475 2.65E-159 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 372 380 - T 21-04-2016 IPR018120 Glycoside hydrolase family 1, active site HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 11 25 - T 21-04-2016 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site HSISS4_RS07900 942a353e2fe33066737efa96417016b0 479 Pfam PF00232 Glycosyl hydrolase family 1 4 475 3.7E-134 T 21-04-2016 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 PIRSF PIRSF000412 1 416 2.3E-162 T 21-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 222 238 - T 21-04-2016 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0004372|GO:0006544|GO:0006563|GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 Pfam PF00464 Serine hydroxymethyltransferase 10 386 1.5E-171 T 21-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 Gene3D G3DSA:3.40.640.10 37 283 1.4E-107 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 51.693 T 21-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 SUPERFAMILY SSF53383 8 416 1.02E-175 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 Gene3D G3DSA:3.90.1150.10 284 416 4.9E-47 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS05785 bcbe4625d934b89c5914c0f3cc3a617f 416 PANTHER PTHR11680 9 416 1.6E-241 T 21-04-2016 IPR001085 Serine hydroxymethyltransferase GO:0016740 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|UniPathway: UPA00193|UniPathway: UPA00288 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 42 - T 21-04-2016 IPR017441 Protein kinase, ATP binding site GO:0005524 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Pfam PF00069 Protein kinase domain 12 234 5.4E-53 T 21-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 SMART SM00740 434 507 3.3E-7 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 SMART SM00740 366 433 7.8E-18 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 SMART SM00740 508 581 3.6E-6 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Gene3D G3DSA:1.10.510.10 79 261 7.6E-52 T 21-04-2016 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 SUPERFAMILY SSF56112 8 276 2.43E-78 T 21-04-2016 IPR011009 Protein kinase-like domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Pfam PF03793 PASTA domain 370 432 6.0E-15 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Pfam PF03793 PASTA domain 511 580 1.6E-10 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Pfam PF03793 PASTA domain 441 505 6.1E-7 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 Gene3D G3DSA:3.30.200.20 3 78 1.6E-25 T 21-04-2016 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 PANTHER PTHR24362 1 324 2.2E-113 T 21-04-2016 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 SMART SM00220 12 270 8.9E-62 T 21-04-2016 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 PANTHER PTHR24362:SF160 1 324 2.2E-113 T 21-04-2016 HSISS4_RS06915 a5dd015d6b027d1c1caf9fa06106c3a0 624 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 132 144 - T 21-04-2016 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 HSISS4_RS08435 3ea74e7723b6a42a0f8574b464fac354 293 Pfam PF14133 Domain of unknown function (DUF4300) 34 268 1.1E-47 T 21-04-2016 IPR025389 Protein of unknown function DUF4300 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 Gene3D G3DSA:3.10.20.70 5 109 1.0E-36 T 21-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 SUPERFAMILY SSF54368 4 105 5.1E-29 T 21-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 ProSitePatterns PS00180 Glutamine synthetase signature 1. 53 71 - T 21-04-2016 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 445 5.5E-168 T 21-04-2016 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 SUPERFAMILY SSF55931 107 445 6.57E-123 T 21-04-2016 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 PANTHER PTHR20852 1 447 1.1E-182 T 21-04-2016 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 443 5.0E-134 T 21-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 Gene3D G3DSA:3.30.590.10 110 433 1.1E-122 T 21-04-2016 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 Reactome: REACT_13 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 SMART SM01230 106 357 7.0E-128 T 21-04-2016 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 2.7E-27 T 21-04-2016 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 HSISS4_RS08555 30d60d06abf0548c9945ca716e665896 447 PANTHER PTHR20852:SF7 1 447 1.1E-182 T 21-04-2016 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 340 6.2E-95 T 21-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 SUPERFAMILY SSF46934 3 56 1.38E-17 T 21-04-2016 IPR009060 UBA-like GO:0005515 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Pfam PF00889 Elongation factor TS 71 323 3.5E-67 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 PANTHER PTHR11741 1 209 3.7E-116 T 21-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 PANTHER PTHR11741 252 343 3.7E-116 T 21-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 SUPERFAMILY SSF54713 56 146 2.4E-20 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 21-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Gene3D G3DSA:1.10.8.10 2 55 2.6E-25 T 21-04-2016 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Gene3D G3DSA:1.10.286.20 243 277 2.1E-6 T 21-04-2016 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Gene3D G3DSA:3.30.479.20 288 326 2.0E-30 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Gene3D G3DSA:3.30.479.20 178 193 2.0E-30 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Gene3D G3DSA:3.30.479.20 57 93 2.0E-30 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 Hamap MF_00050 Elongation factor Ts [tsf]. 1 341 66.31 T 21-04-2016 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 21-04-2016 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 SUPERFAMILY SSF54713 249 340 4.84E-39 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00480 a0eaee5477fd2a5d278ff885fa425a93 346 SUPERFAMILY SSF54713 152 206 4.84E-39 T 21-04-2016 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 SMART SM00100 1 123 1.4E-9 T 21-04-2016 IPR000595 Cyclic nucleotide-binding domain HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 SUPERFAMILY SSF46785 141 210 5.81E-7 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 PANTHER PTHR24567 27 209 1.2E-38 T 21-04-2016 HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 SUPERFAMILY SSF51206 2 126 5.24E-23 T 21-04-2016 IPR018490 Cyclic nucleotide-binding-like HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 Pfam PF13545 Crp-like helix-turn-helix domain 143 208 9.2E-9 T 21-04-2016 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 Gene3D G3DSA:1.10.10.10 140 209 1.5E-7 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 Gene3D G3DSA:2.60.120.10 10 126 8.3E-23 T 21-04-2016 IPR014710 RmlC-like jelly roll fold HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 Pfam PF00027 Cyclic nucleotide-binding domain 25 110 2.1E-17 T 21-04-2016 IPR000595 Cyclic nucleotide-binding domain HSISS4_RS00805 4a493efa8c6dfa4209132c5c942dcca1 212 PANTHER PTHR24567:SF26 27 209 1.2E-38 T 21-04-2016 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 PANTHER PTHR32219:SF5 5 265 2.1E-55 T 21-04-2016 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 Gene3D G3DSA:3.10.290.10 184 239 1.7E-17 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 Pfam PF01479 S4 domain 186 232 1.3E-7 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 SMART SM00363 186 248 1.3E-9 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 SUPERFAMILY SSF55174 183 256 1.53E-28 T 21-04-2016 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 SUPERFAMILY SSF55174 39 130 1.53E-28 T 21-04-2016 HSISS4_RS03660 b6e26dd6da0f5516316fc2bfc805607e 267 PANTHER PTHR32219 5 265 2.1E-55 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 Gene3D G3DSA:3.40.710.10 280 689 3.7E-90 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 PANTHER PTHR32282:SF0 27 603 1.8E-186 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 PANTHER PTHR32282:SF0 623 663 1.8E-186 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 Pfam PF00905 Penicillin binding protein transpeptidase domain 373 640 2.8E-34 T 21-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 111 669 6.5E-161 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 Gene3D G3DSA:1.10.3810.10 102 279 1.8E-69 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 SUPERFAMILY SSF56601 259 281 9.27E-89 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 SUPERFAMILY SSF56601 314 688 9.27E-89 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 PANTHER PTHR32282 27 603 1.8E-186 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 PANTHER PTHR32282 623 663 1.8E-186 T 21-04-2016 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 Pfam PF00912 Transglycosylase 101 277 4.9E-61 T 21-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HSISS4_RS01110 ae5c9c2e169c5d334e9ab9bab9eab191 763 SUPERFAMILY SSF53955 91 302 8.72E-69 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 155 243 1.0E-25 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 670 759 4.0E-30 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 258 345 4.3E-26 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 467 553 1.6E-33 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 571 656 1.5E-28 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF08481 GBS Bsp-like repeat 361 450 1.2E-26 T 21-04-2016 IPR013688 GBS Bsp-like HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 783 969 4.1E-54 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 PANTHER PTHR30404 779 971 1.7E-51 T 21-04-2016 HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 SUPERFAMILY SSF53187 781 974 5.34E-54 T 21-04-2016 HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 Gene3D G3DSA:3.40.630.40 781 973 2.5E-62 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 SMART SM00646 841 969 2.5E-40 T 21-04-2016 IPR002508 Cell wall hydrolase/autolysin, catalytic GO:0008745|GO:0009253 HSISS4_RS04775 ce4d5086fa2aa98a642a5e416eca1b6c 976 PANTHER PTHR30404:SF0 779 971 1.7E-51 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF69360 1243 1429 1.12E-37 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 4 26 4.7E-7 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF69360 1133 1228 4.19E-14 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:2.10.270.10 1133 1224 1.9E-11 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:2.10.270.10 1306 1374 4.3E-21 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:2.10.270.10 1375 1445 6.4E-11 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF51445 895 1065 6.76E-27 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF69360 173 226 2.88E-7 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Pfam PF02324 Glycosyl hydrolase family 70 282 1143 0.0 T 21-04-2016 IPR003318 Glycoside hydrolase, family 70, catalytic domain GO:0009250|GO:0046527 KEGG: 00500+2.4.1.5 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:2.10.270.10 174 216 6.1E-6 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Pfam PF01473 Putative cell wall binding repeat 1297 1314 5.6E-5 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Pfam PF01473 Putative cell wall binding repeat 1159 1175 0.072 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Pfam PF01473 Putative cell wall binding repeat 1361 1379 0.22 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:3.20.20.80 918 1005 5.3E-21 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1306 1370 5.4E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1243 1304 3.7E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 1371 1433 3.0E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:3.20.20.80 404 627 1.3E-20 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:3.20.20.80 660 715 1.3E-20 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 Gene3D G3DSA:2.10.270.10 1245 1305 1.6E-15 T 21-04-2016 HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF51445 662 709 3.99E-29 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF51445 409 544 3.99E-29 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS03960 788a2ab28bb1814f95b4d8f2b06257bd 1452 SUPERFAMILY SSF51445 583 625 3.99E-29 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06830 e92ab9dc7c4245de866e50dab6d4320a 186 SUPERFAMILY SSF55729 14 147 3.86E-16 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS06830 e92ab9dc7c4245de866e50dab6d4320a 186 Pfam PF13508 Acetyltransferase (GNAT) domain 45 134 4.5E-8 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS06830 e92ab9dc7c4245de866e50dab6d4320a 186 Gene3D G3DSA:3.40.630.30 11 154 3.5E-31 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 Hamap MF_00124 Thymidine kinase [tdk]. 1 187 33.486 T 21-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 Pfam PF00265 Thymidine kinase 2 184 2.7E-48 T 21-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 SUPERFAMILY SSF52540 2 140 3.0E-36 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 SUPERFAMILY SSF57716 140 190 4.75E-17 T 21-04-2016 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 PANTHER PTHR11441 1 190 4.2E-64 T 21-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 171 184 - T 21-04-2016 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 Gene3D G3DSA:3.30.60.20 140 190 1.7E-20 T 21-04-2016 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 PIRSF PIRSF035805 1 195 3.3E-57 T 21-04-2016 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199 HSISS4_RS05805 f0275a335617f61d4ca9f5dec14e5feb 198 Gene3D G3DSA:3.40.50.300 6 106 2.4E-4 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 Pfam PF00005 ABC transporter 23 165 1.6E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 SMART SM00382 32 215 3.7E-15 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 SUPERFAMILY SSF50331 240 345 2.27E-11 T 21-04-2016 IPR008995 Molybdate/tungstate binding, C-terminal HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 Gene3D G3DSA:3.40.50.300 3 238 6.2E-82 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 Pfam PF08402 TOBE domain 276 344 8.8E-5 T 21-04-2016 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 PANTHER PTHR24220 7 381 8.7E-177 T 21-04-2016 HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 PANTHER PTHR24220:SF150 7 381 8.7E-177 T 21-04-2016 HSISS4_RS07350 e7126af56a963c3885ca1e5cff57a6aa 384 SUPERFAMILY SSF52540 5 246 3.59E-85 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07070 6ab1db78758cde4425fde191a664693b 344 PANTHER PTHR22916:SF2 2 210 1.2E-39 T 21-04-2016 HSISS4_RS07070 6ab1db78758cde4425fde191a664693b 344 PANTHER PTHR22916 2 210 1.2E-39 T 21-04-2016 HSISS4_RS07070 6ab1db78758cde4425fde191a664693b 344 SUPERFAMILY SSF53448 2 220 5.44E-39 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07070 6ab1db78758cde4425fde191a664693b 344 Gene3D G3DSA:3.90.550.10 1 248 5.6E-37 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07070 6ab1db78758cde4425fde191a664693b 344 Pfam PF00535 Glycosyl transferase family 2 4 115 8.1E-25 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 PANTHER PTHR21235 1 237 3.6E-93 T 21-04-2016 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 SUPERFAMILY SSF51366 1 236 9.42E-72 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 Gene3D G3DSA:3.20.20.70 1 236 1.4E-81 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 232 1.7E-82 T 21-04-2016 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 PANTHER PTHR21235:SF15 1 237 3.6E-93 T 21-04-2016 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 Pfam PF00977 Histidine biosynthesis protein 2 230 9.8E-78 T 21-04-2016 IPR006062 Histidine biosynthesis GO:0000105 HSISS4_RS03910 7395ba836fdd037310b0efbc434f2da9 239 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 237 35.799 T 21-04-2016 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16|UniPathway: UPA00031 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 PANTHER PTHR11712 1 409 1.4E-175 T 21-04-2016 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 21-04-2016 IPR018201 Beta-ketoacyl synthase, active site HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 PIRSF PIRSF000447 1 410 2.2E-178 T 21-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 364 3.3E-34 T 21-04-2016 IPR014031 Beta-ketoacyl synthase, C-terminal HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 SMART SM00825 Beta-ketoacyl synthase 6 399 1.8E-13 T 21-04-2016 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 SUPERFAMILY SSF53901 214 408 6.29E-68 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 Gene3D G3DSA:3.40.47.10 263 409 4.5E-56 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 SUPERFAMILY SSF53901 4 251 3.32E-71 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 406 6.0E-176 T 21-04-2016 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 UniPathway: UPA00094 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 Gene3D G3DSA:3.40.47.10 2 259 1.7E-71 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS01815 5c7371107eb4cabca1eb2976514a9230 410 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 1.6E-55 T 21-04-2016 IPR014030 Beta-ketoacyl synthase, N-terminal HSISS4_RS07525 62440538af36d9f7f20198540d449193 323 PANTHER PTHR10587 93 320 4.1E-33 T 21-04-2016 HSISS4_RS07525 62440538af36d9f7f20198540d449193 323 Pfam PF01522 Polysaccharide deacetylase 116 235 4.5E-22 T 21-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HSISS4_RS07525 62440538af36d9f7f20198540d449193 323 Gene3D G3DSA:3.20.20.370 90 321 1.5E-46 T 21-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HSISS4_RS07525 62440538af36d9f7f20198540d449193 323 SUPERFAMILY SSF88713 109 320 1.01E-41 T 21-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HSISS4_RS05440 a7f9f827a87eab2e13ddd1466fd6152b 194 Gene3D G3DSA:3.40.630.30 17 184 2.0E-35 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05440 a7f9f827a87eab2e13ddd1466fd6152b 194 PANTHER PTHR13256 17 184 1.0E-27 T 21-04-2016 HSISS4_RS05440 a7f9f827a87eab2e13ddd1466fd6152b 194 SUPERFAMILY SSF55729 17 184 1.73E-34 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05440 a7f9f827a87eab2e13ddd1466fd6152b 194 Pfam PF13302 Acetyltransferase (GNAT) domain 23 161 6.1E-16 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 SUPERFAMILY SSF48179 152 255 5.44E-29 T 21-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 23.999 T 21-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 PANTHER PTHR11645 1 256 8.4E-81 T 21-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 PANTHER PTHR11645:SF0 1 256 8.4E-81 T 21-04-2016 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 256 2.3E-77 T 21-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 Gene3D G3DSA:3.40.50.720 3 149 3.2E-40 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 Gene3D G3DSA:1.10.3730.10 152 255 1.2E-32 T 21-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 SUPERFAMILY SSF51735 1 151 1.23E-32 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 212 234 - T 21-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 PIRSF PIRSF000193 1 256 1.2E-69 T 21-04-2016 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 89 2.3E-16 T 21-04-2016 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal HSISS4_RS09010 276931edbdc9102d5b1f1577b88c5731 256 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 256 3.8E-34 T 21-04-2016 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|UniPathway: UPA00098 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 SUPERFAMILY SSF63737 9 192 1.16E-47 T 21-04-2016 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 Gene3D G3DSA:1.10.390.10 303 451 1.2E-49 T 21-04-2016 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 SUPERFAMILY SSF55486 202 450 1.04E-79 T 21-04-2016 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PANTHER PTHR11533 7 844 1.8E-251 T 21-04-2016 IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase GO:0006508 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 309 321 8.2E-29 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 176 191 8.2E-29 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 255 265 8.2E-29 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 290 305 8.2E-29 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 127 142 8.2E-29 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 Pfam PF01433 Peptidase family M1 9 383 2.2E-133 T 21-04-2016 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 Pfam PF11838 ERAP1-like C-terminal domain 513 826 1.4E-38 T 21-04-2016 IPR024571 ERAP1-like C-terminal domain HSISS4_RS04865 620ba6d4cb417e12d493363208da02a6 846 PANTHER PTHR11533:SF163 7 844 1.8E-251 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 PANTHER PTHR18966 40 274 6.7E-32 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 PANTHER PTHR18966:SF152 40 274 6.7E-32 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 46 272 8.6E-59 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 SMART SM00062 45 273 8.2E-68 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 Gene3D G3DSA:3.40.190.10 233 275 8.2E-40 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 Gene3D G3DSA:3.40.190.10 42 122 8.2E-40 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 Gene3D G3DSA:3.40.190.10 123 232 9.3E-21 T 21-04-2016 HSISS4_RS05465 e3912711072fefdb332cf94fe4fc0685 283 SUPERFAMILY SSF53850 6 273 3.5E-65 T 21-04-2016 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 428 1.0E-147 T 21-04-2016 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 PANTHER PTHR15239 404 541 4.5E-118 T 21-04-2016 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 PANTHER PTHR15239 1 387 4.5E-118 T 21-04-2016 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 Pfam PF05670 Domain of unknown function (DUF814) 435 520 1.1E-26 T 21-04-2016 IPR008532 Domain of unknown function DUF814 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 Gene3D G3DSA:3.40.970.40 239 275 3.9E-10 T 21-04-2016 HSISS4_RS05085 d3e3a210211900bd4589616295dcc55f 552 Gene3D G3DSA:2.30.310.10 1 167 1.9E-60 T 21-04-2016 HSISS4_RS03665 9b072400bf498a0c96aeaa18ef939834 291 Gene3D G3DSA:1.20.5.300 39 81 2.8E-4 T 21-04-2016 HSISS4_RS03665 9b072400bf498a0c96aeaa18ef939834 291 PANTHER PTHR35794 1 242 7.2E-62 T 21-04-2016 HSISS4_RS03665 9b072400bf498a0c96aeaa18ef939834 291 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 2.1E-15 T 21-04-2016 IPR019933 DivIVA domain HSISS4_RS03665 9b072400bf498a0c96aeaa18ef939834 291 Pfam PF05103 DivIVA protein 3 143 9.4E-44 T 21-04-2016 IPR007793 DivIVA family HSISS4_RS03665 9b072400bf498a0c96aeaa18ef939834 291 PANTHER PTHR35794:SF2 1 242 7.2E-62 T 21-04-2016 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 SUPERFAMILY SSF55200 86 174 9.55E-31 T 21-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 11 80 3.4E-29 T 21-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 174 29.517 T 21-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 Gene3D G3DSA:3.10.20.80 6 82 1.7E-33 T 21-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 87 171 8.9E-35 T 21-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 Gene3D G3DSA:3.30.110.10 83 175 4.2E-35 T 21-04-2016 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 SUPERFAMILY SSF54364 9 82 7.72E-28 T 21-04-2016 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 11 171 3.5E-63 T 21-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 ProSitePatterns PS00938 Initiation factor 3 signature. 62 75 - T 21-04-2016 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 HSISS4_RS04500 ca861abeac707fc0738d70a7e8c852df 176 PANTHER PTHR10938 4 172 6.1E-63 T 21-04-2016 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 SUPERFAMILY SSF110849 7 98 5.75E-28 T 21-04-2016 IPR003115 ParB/Sulfiredoxin HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 2 179 1.1E-58 T 21-04-2016 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 SUPERFAMILY SSF109709 91 197 7.59E-34 T 21-04-2016 HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 PANTHER PTHR33375:SF3 2 254 1.9E-96 T 21-04-2016 HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 SMART SM00470 6 96 1.7E-33 T 21-04-2016 IPR003115 ParB/Sulfiredoxin HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 Pfam PF02195 ParB-like nuclease domain 8 95 4.1E-26 T 21-04-2016 IPR003115 ParB/Sulfiredoxin HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 PANTHER PTHR33375 2 254 1.9E-96 T 21-04-2016 HSISS4_RS09750 b9f1080a4162b2be247640b4540f8fe7 255 Gene3D G3DSA:3.90.1530.10 2 102 7.1E-37 T 21-04-2016 HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 SUPERFAMILY SSF52980 744 928 9.12E-11 T 21-04-2016 IPR011335 Restriction endonuclease type II-like HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 Hamap MF_01453 ATP-dependent helicase/deoxyribonuclease subunit B [rexB]. 1 1074 42.374 T 21-04-2016 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 PANTHER PTHR30591:SF1 5 1070 1.1E-71 T 21-04-2016 HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 Pfam PF12705 PD-(D/E)XK nuclease superfamily 746 1023 5.7E-31 T 21-04-2016 HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 PANTHER PTHR30591 5 1070 1.1E-71 T 21-04-2016 HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 Gene3D G3DSA:3.40.50.300 282 371 1.9E-8 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 Gene3D G3DSA:3.40.50.300 544 588 1.9E-8 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 SUPERFAMILY SSF52540 290 651 2.02E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08215 c282e79179f88bf189b8581cc9df63c6 1106 TIGRFAM TIGR02774 rexB_recomb: ATP-dependent nuclease subunit B 2 1068 0.0 T 21-04-2016 IPR014141 DNA helicase subunit RexB GO:0016788|GO:0016817 HSISS4_RS01480 b3e25ce7caf15710551dcd755f4ef8bb 271 Pfam PF03609 PTS system sorbose-specific iic component 6 241 3.7E-67 T 21-04-2016 IPR004700 Phosphotransferase system, sorbose-specific IIC subunit GO:0009401|GO:0016021 HSISS4_RS01480 b3e25ce7caf15710551dcd755f4ef8bb 271 PANTHER PTHR32502 1 269 4.9E-144 T 21-04-2016 HSISS4_RS01480 b3e25ce7caf15710551dcd755f4ef8bb 271 PANTHER PTHR32502:SF10 1 269 4.9E-144 T 21-04-2016 HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 Gene3D G3DSA:2.60.120.260 145 237 1.2E-5 T 21-04-2016 IPR008979 Galactose-binding domain-like HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 Pfam PF13229 Right handed beta helix region 359 555 9.8E-6 T 21-04-2016 HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 Gene3D G3DSA:2.160.20.10 289 673 4.3E-44 T 21-04-2016 IPR012334 Pectin lyase fold HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 605 627 9900.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 635 659 3500.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 423 444 3100.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 478 500 0.3 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 535 558 850.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 454 476 44.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 511 534 730.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SMART SM00710 569 600 1800.0 T 21-04-2016 IPR006626 Parallel beta-helix repeat HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 SUPERFAMILY SSF51126 289 648 5.29E-40 T 21-04-2016 IPR011050 Pectin lyase fold/virulence factor HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 Pfam PF04650 YSIRK type signal peptide 6 28 5.1E-9 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS03520 88c7ea593928deebafca097d18a7b291 1150 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 6 40 1.6E-9 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 Gene3D G3DSA:3.40.50.720 79 215 9.8E-50 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 PANTHER PTHR35786 1 218 1.2E-99 T 21-04-2016 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 SUPERFAMILY SSF46785 8 79 2.04E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 Gene3D G3DSA:1.10.10.10 5 76 1.3E-29 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 2 212 38.197 T 21-04-2016 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 Pfam PF06971 Putative DNA-binding protein N-terminus 6 54 2.5E-17 T 21-04-2016 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 SUPERFAMILY SSF51735 84 209 3.02E-24 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 Pfam PF02629 CoA binding domain 83 182 5.8E-25 T 21-04-2016 IPR003781 CoA-binding GO:0048037 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 SMART SM00881 80 183 2.9E-13 T 21-04-2016 IPR003781 CoA-binding GO:0048037 HSISS4_RS07050 9473bc869c75311cfddedfb1cea0a4ff 219 PANTHER PTHR35786:SF1 1 218 1.2E-99 T 21-04-2016 HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 SUPERFAMILY SSF63817 33 227 2.35E-46 T 21-04-2016 IPR023365 Sortase domain HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 PANTHER PTHR33393:SF3 25 251 1.2E-44 T 21-04-2016 HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 Pfam PF04203 Sortase family 102 227 4.4E-28 T 21-04-2016 IPR005754 Sortase family HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 TIGRFAM TIGR01076 sortase_fam: sortase 100 226 1.1E-22 T 21-04-2016 IPR005754 Sortase family HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 PANTHER PTHR33393 25 251 1.2E-44 T 21-04-2016 HSISS4_RS05850 e596ed38fa9ea2fa1e5bf916246ffe52 253 Gene3D G3DSA:2.40.260.10 90 229 1.4E-42 T 21-04-2016 IPR023365 Sortase domain HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 4 449 4.1E-91 T 21-04-2016 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 Pfam PF13091 PLD-like domain 290 415 5.0E-21 T 21-04-2016 IPR025202 Phospholipase D-like domain HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 Pfam PF13091 PLD-like domain 105 246 1.6E-12 T 21-04-2016 IPR025202 Phospholipase D-like domain HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 SUPERFAMILY SSF56024 266 432 2.47E-34 T 21-04-2016 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 SUPERFAMILY SSF56024 71 278 1.13E-43 T 21-04-2016 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 SMART SM00155 186 213 1.5E-5 T 21-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 SMART SM00155 362 389 1.1E-4 T 21-04-2016 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 PANTHER PTHR21248 59 449 6.6E-93 T 21-04-2016 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 PANTHER PTHR21248:SF5 59 449 6.6E-93 T 21-04-2016 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 Gene3D G3DSA:3.30.870.10 81 283 2.2E-47 T 21-04-2016 HSISS4_RS05970 58251905304fb35a1b5f06136c2deb0e 449 Gene3D G3DSA:3.30.870.10 286 437 9.7E-32 T 21-04-2016 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 21-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 Gene3D G3DSA:3.90.79.10 5 128 3.2E-32 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 Pfam PF00293 NUDIX domain 7 125 6.8E-18 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 PANTHER PTHR22769 3 127 2.3E-31 T 21-04-2016 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.4E-7 T 21-04-2016 IPR020476 NUDIX hydrolase HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.4E-7 T 21-04-2016 IPR020476 NUDIX hydrolase HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 PANTHER PTHR22769:SF35 3 127 2.3E-31 T 21-04-2016 HSISS4_RS03395 d18cc16b8b5462f4877da899c99cb493 129 SUPERFAMILY SSF55811 3 127 4.2E-34 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 SUPERFAMILY SSF48695 148 229 1.33E-5 T 21-04-2016 IPR011031 Multihaem cytochrome HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 SMART SM00422 4 73 4.2E-24 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 SUPERFAMILY SSF46955 4 112 7.33E-25 T 21-04-2016 IPR009061 Putative DNA-binding domain HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 Gene3D G3DSA:1.10.1660.10 4 111 2.1E-27 T 21-04-2016 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 PANTHER PTHR30204 1 189 4.2E-23 T 21-04-2016 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 6.2E-7 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 6.2E-7 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 6.2E-7 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS07720 068b84ffc2953adc24155b4a34522750 242 Pfam PF13411 MerR HTH family regulatory protein 4 72 1.4E-20 T 21-04-2016 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 PANTHER PTHR11933 1 366 2.1E-211 T 21-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 8 360 1.5E-137 T 21-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 7 361 41.33 T 21-04-2016 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 Gene3D G3DSA:2.30.30.280 214 281 6.2E-32 T 21-04-2016 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 PANTHER PTHR11933:SF10 1 366 2.1E-211 T 21-04-2016 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 Pfam PF03054 tRNA methyl transferase 8 360 6.8E-147 T 21-04-2016 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 SUPERFAMILY SSF52402 5 244 2.43E-59 T 21-04-2016 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 Gene3D G3DSA:2.40.30.10 283 371 9.0E-33 T 21-04-2016 HSISS4_RS09625 0c15287a955d3a8db6fb5a126427b4d7 373 Gene3D G3DSA:3.40.50.620 4 212 5.7E-105 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS04195 dfe9a88549abc73474b529dbe0181bea 239 Gene3D G3DSA:3.40.390.10 92 237 1.5E-19 T 21-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 HSISS4_RS04195 dfe9a88549abc73474b529dbe0181bea 239 Pfam PF00413 Matrixin 108 238 1.5E-7 T 21-04-2016 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 HSISS4_RS04195 dfe9a88549abc73474b529dbe0181bea 239 SUPERFAMILY SSF55486 89 237 1.05E-24 T 21-04-2016 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 121 255 3.4E-31 T 21-04-2016 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 140 157 - T 21-04-2016 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 PANTHER PTHR20836 1 255 4.9E-84 T 21-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 3 255 28.398 T 21-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 Gene3D G3DSA:3.40.50.720 3 128 1.1E-12 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 3 255 4.0E-75 T 21-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 Gene3D G3DSA:3.30.360.10 129 224 2.9E-36 T 21-04-2016 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 7.3E-30 T 21-04-2016 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 SUPERFAMILY SSF51735 3 145 1.36E-35 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 PIRSF PIRSF000161 1 255 4.6E-69 T 21-04-2016 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|UniPathway: UPA00034 HSISS4_RS01935 ba39089e38ab25d48972d60098dd84e9 255 SUPERFAMILY SSF55347 119 227 5.23E-39 T 21-04-2016 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 PANTHER PTHR20941 1 151 7.2E-70 T 21-04-2016 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 SUPERFAMILY SSF55083 1 157 2.49E-55 T 21-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 1.5E-47 T 21-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 88 99 - T 21-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 1.8E-38 T 21-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS07360 0afa46d425f7690ab55ee1cac81fad19 163 Gene3D G3DSA:3.30.70.560 3 156 1.9E-58 T 21-04-2016 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|UniPathway: UPA00077 HSISS4_RS04415 2538d2089112a18fa8d6f3d4d8c408a6 128 Gene3D G3DSA:2.40.128.20 2 127 3.0E-23 T 21-04-2016 IPR012674 Calycin HSISS4_RS04415 2538d2089112a18fa8d6f3d4d8c408a6 128 SUPERFAMILY SSF50814 1 127 4.62E-35 T 21-04-2016 IPR011038 Calycin-like HSISS4_RS04415 2538d2089112a18fa8d6f3d4d8c408a6 128 Pfam PF09148 Domain of unknown function (DUF1934) 3 124 1.8E-19 T 21-04-2016 IPR015231 Protein of unknown function DUF1934 HSISS4_RS09735 fa8a01546572fc42502e58e5bd55acfb 227 Pfam PF06912 Protein of unknown function (DUF1275) 18 213 4.4E-31 T 21-04-2016 IPR010699 Protein of unknown function DUF1275 HSISS4_RS09735 fa8a01546572fc42502e58e5bd55acfb 227 PANTHER PTHR37314:SF2 1 226 9.7E-31 T 21-04-2016 HSISS4_RS09735 fa8a01546572fc42502e58e5bd55acfb 227 PANTHER PTHR37314 1 226 9.7E-31 T 21-04-2016 HSISS4_RS01065 4f87051dfe7158c530ae5c3e688db844 151 Pfam PF04397 LytTr DNA-binding domain 54 149 7.7E-21 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS01065 4f87051dfe7158c530ae5c3e688db844 151 PANTHER PTHR37299 18 151 6.3E-12 T 21-04-2016 HSISS4_RS01065 4f87051dfe7158c530ae5c3e688db844 151 SMART SM00850 53 150 7.6E-23 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS01065 4f87051dfe7158c530ae5c3e688db844 151 Gene3D G3DSA:2.40.50.40 46 113 4.6E-15 T 21-04-2016 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 TIGRFAM TIGR01835 HMG-CoA-S_prok: hydroxymethylglutaryl-CoA synthase 3 385 1.5E-164 T 21-04-2016 IPR011554 Hydroxymethylglutaryl-CoA synthase, prokaryotic KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 Gene3D G3DSA:3.40.47.10 1 251 9.7E-81 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 SUPERFAMILY SSF53901 169 386 6.4E-63 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 PANTHER PTHR11877:SF26 3 386 1.1E-89 T 21-04-2016 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 Pfam PF08540 Hydroxymethylglutaryl-coenzyme A synthase C terminal 257 347 5.1E-14 T 21-04-2016 IPR013746 Hydroxymethylglutaryl-coenzyme A synthase C-terminal domain GO:0004421|GO:0008299 KEGG: 00072+2.3.3.10|KEGG: 00280+2.3.3.10|KEGG: 00650+2.3.3.10|KEGG: 00900+2.3.3.10|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7571|MetaCyc: PWY-922|Reactome: REACT_22258|UniPathway: UPA00058 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 Pfam PF01154 Hydroxymethylglutaryl-coenzyme A synthase N terminal 7 164 2.1E-9 T 21-04-2016 IPR013528 Hydroxymethylglutaryl-coenzyme A synthase, N-terminal GO:0004421|GO:0008299 Reactome: REACT_22258 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 PANTHER PTHR11877 3 386 1.1E-89 T 21-04-2016 HSISS4_RS02710 437447714b422a2a749d1b92ea6478be 388 SUPERFAMILY SSF53901 3 166 1.5E-37 T 21-04-2016 IPR016039 Thiolase-like GO:0003824|GO:0008152 HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 PANTHER PTHR22778:SF21 3 307 2.2E-109 T 21-04-2016 HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 Pfam PF00581 Rhodanese-like domain 121 215 1.1E-11 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 Hamap MF_00469 UPF0176 protein YceA [yceA]. 3 272 39.662 T 21-04-2016 IPR020936 Uncharacterised protein family UPF0176 HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 SUPERFAMILY SSF52821 110 253 5.5E-34 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 Gene3D G3DSA:3.40.250.10 104 233 2.8E-34 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 Pfam PF12368 Rhodanase C-terminal 227 293 2.4E-13 T 21-04-2016 IPR022111 Rhodanase, C-terminal HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 PANTHER PTHR22778 3 307 2.2E-109 T 21-04-2016 HSISS4_RS02545 8e1162ba6b1b8e9b322d468fc8b1b5eb 327 SMART SM00450 120 221 4.2E-19 T 21-04-2016 IPR001763 Rhodanese-like domain HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 SUPERFAMILY SSF47616 122 256 2.78E-32 T 21-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 Gene3D G3DSA:1.20.1050.10 129 253 1.5E-44 T 21-04-2016 IPR010987 Glutathione S-transferase, C-terminal-like HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 Pfam PF13410 Glutathione S-transferase, C-terminal domain 173 242 3.8E-11 T 21-04-2016 HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 PANTHER PTHR11260:SF258 16 262 5.9E-101 T 21-04-2016 HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 Pfam PF02798 Glutathione S-transferase, N-terminal domain 43 125 1.4E-4 T 21-04-2016 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 SUPERFAMILY SSF52833 38 129 4.49E-15 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 PANTHER PTHR11260 16 262 5.9E-101 T 21-04-2016 HSISS4_RS05815 52c28c13ee3bfceee592abb4ffa72b9b 262 Gene3D G3DSA:3.40.30.10 31 128 2.0E-23 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 PIRSF PIRSF005572 1 381 3.7E-112 T 21-04-2016 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 Gene3D G3DSA:3.90.1150.10 247 372 2.4E-29 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 SUPERFAMILY SSF53383 1 374 2.33E-92 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 PANTHER PTHR11601 1 381 1.2E-191 T 21-04-2016 HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 PANTHER PTHR11601:SF50 1 381 1.2E-191 T 21-04-2016 HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 21-04-2016 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 Pfam PF00266 Aminotransferase class-V 2 366 1.2E-64 T 21-04-2016 IPR000192 Aminotransferase class V domain HSISS4_RS01885 9c604db7f4af776858b3816f96c7abbb 381 Gene3D G3DSA:3.40.640.10 14 246 1.3E-76 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS06080 9c78824a28bcbcac621197b2ae5e0406 245 PANTHER PTHR30294:SF6 1 233 3.4E-44 T 21-04-2016 HSISS4_RS06080 9c78824a28bcbcac621197b2ae5e0406 245 PANTHER PTHR30294 1 233 3.4E-44 T 21-04-2016 HSISS4_RS06080 9c78824a28bcbcac621197b2ae5e0406 245 Pfam PF01061 ABC-2 type transporter 2 205 1.1E-12 T 21-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HSISS4_RS06080 9c78824a28bcbcac621197b2ae5e0406 245 PIRSF PIRSF006648 3 243 8.5E-15 T 21-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 ProSitePatterns PS00760 Signal peptidases I lysine active site. 83 95 - T 21-04-2016 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 Pfam PF00717 Peptidase S24-like 38 105 3.7E-17 T 21-04-2016 IPR019759 Peptidase S24/S26A/S26B HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 ProSitePatterns PS00501 Signal peptidases I serine active site. 41 48 - T 21-04-2016 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: REACT_15380 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PANTHER PTHR12383:SF14 2 127 1.3E-44 T 21-04-2016 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PANTHER PTHR12383:SF14 146 213 1.3E-44 T 21-04-2016 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PANTHER PTHR12383 2 127 1.3E-44 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PANTHER PTHR12383 146 213 1.3E-44 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 Gene3D G3DSA:2.10.109.10 164 211 9.0E-31 T 21-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 Gene3D G3DSA:2.10.109.10 29 91 9.0E-31 T 21-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 18 205 5.5E-44 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 SUPERFAMILY SSF51306 30 210 3.44E-49 T 21-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 81 93 1.9E-20 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 32 48 1.9E-20 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS08505 7a11b33c402f252c98eef1622bd4aab3 213 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 164 183 1.9E-20 T 21-04-2016 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 29 397 0.0 T 21-04-2016 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 Pfam PF01960 ArgJ family 16 397 8.3E-146 T 21-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 PANTHER PTHR23100 1 397 4.3E-187 T 21-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 4 397 1.4E-150 T 21-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 Gene3D G3DSA:3.60.70.12 5 270 1.8E-94 T 21-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 PANTHER PTHR23100:SF0 1 397 4.3E-187 T 21-04-2016 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 SUPERFAMILY SSF56266 11 393 2.35E-136 T 21-04-2016 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS02170 7db2a69f98fe66e050b306ecaf347598 397 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 397 144.784 T 21-04-2016 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154|UniPathway: UPA00068|UniPathway: UPA00068 HSISS4_RS01330 5b5287316a09ac28c99d6500a6f9047a 237 PANTHER PTHR33620 12 237 3.4E-41 T 21-04-2016 HSISS4_RS01330 5b5287316a09ac28c99d6500a6f9047a 237 Hamap MF_01385 Urease accessory protein UreF [ureF]. 13 237 24.557 T 21-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 HSISS4_RS01330 5b5287316a09ac28c99d6500a6f9047a 237 PANTHER PTHR33620:SF1 12 237 3.4E-41 T 21-04-2016 HSISS4_RS01330 5b5287316a09ac28c99d6500a6f9047a 237 Pfam PF01730 UreF 45 193 9.7E-26 T 21-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 HSISS4_RS01330 5b5287316a09ac28c99d6500a6f9047a 237 PIRSF PIRSF009467 10 237 8.1E-74 T 21-04-2016 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 HSISS4_RS03140 4a11d6ba2b3c53b9ad33a1e9ee839aa9 245 SUPERFAMILY SSF56281 14 241 9.47E-9 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS03140 4a11d6ba2b3c53b9ad33a1e9ee839aa9 245 Pfam PF14234 Domain of unknown function (DUF4336) 18 175 5.9E-19 T 21-04-2016 IPR025638 Protein of unknown function DUF4336 HSISS4_RS03140 4a11d6ba2b3c53b9ad33a1e9ee839aa9 245 PANTHER PTHR33835 21 242 8.5E-26 T 21-04-2016 HSISS4_RS03920 b22d8019089470cfcd2505e579fef448 112 PANTHER PTHR21256 6 108 2.7E-61 T 21-04-2016 HSISS4_RS03920 b22d8019089470cfcd2505e579fef448 112 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 52 105 3.0E-23 T 21-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HSISS4_RS03920 b22d8019089470cfcd2505e579fef448 112 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 102 2.6E-36 T 21-04-2016 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HSISS4_RS03920 b22d8019089470cfcd2505e579fef448 112 SUPERFAMILY SSF141734 5 108 1.31E-48 T 21-04-2016 HSISS4_RS03920 b22d8019089470cfcd2505e579fef448 112 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 3 106 30.438 T 21-04-2016 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19|UniPathway: UPA00031 HSISS4_RS07615 5ef3a9626b53f7529768e8157e707856 226 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 212 6.9E-16 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07615 5ef3a9626b53f7529768e8157e707856 226 Gene3D G3DSA:1.10.3720.10 13 213 2.4E-39 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07615 5ef3a9626b53f7529768e8157e707856 226 SUPERFAMILY SSF161098 12 198 2.62E-40 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS07615 5ef3a9626b53f7529768e8157e707856 226 PANTHER PTHR30614 1 218 4.3E-66 T 21-04-2016 HSISS4_RS07615 5ef3a9626b53f7529768e8157e707856 226 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 107 5.8E-31 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS06135 f57435c759d8b8530d1de5c8732271e3 666 PIRSF PIRSF018968 4 666 1.6E-75 T 21-04-2016 IPR027022 ABC transporter permease protein, BceB-type GO:0006810 HSISS4_RS06135 f57435c759d8b8530d1de5c8732271e3 666 PANTHER PTHR30489 1 656 1.3E-29 T 21-04-2016 HSISS4_RS06135 f57435c759d8b8530d1de5c8732271e3 666 Pfam PF02687 FtsX-like permease family 63 182 9.6E-16 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 PANTHER PTHR10587:SF94 19 536 1.3E-30 T 21-04-2016 HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 Pfam PF07238 PilZ domain 509 606 5.2E-14 T 21-04-2016 IPR009875 PilZ domain GO:0035438 HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 SUPERFAMILY SSF53448 77 374 6.0E-39 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 Gene3D G3DSA:3.90.550.10 78 316 3.4E-18 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 PANTHER PTHR10587 19 536 1.3E-30 T 21-04-2016 HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 SUPERFAMILY SSF141371 512 610 1.96E-10 T 21-04-2016 HSISS4_RS09525 297cb293f22117002cc0fc2eee149667 741 Pfam PF13641 Glycosyltransferase like family 2 78 317 1.4E-26 T 21-04-2016 HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 PANTHER PTHR36528 1 756 4.4E-63 T 21-04-2016 HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 Gene3D G3DSA:1.10.3210.10 8 87 1.7E-8 T 21-04-2016 IPR006674 HD domain HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 9 635 1.7E-128 T 21-04-2016 IPR013408 CRISPR-associated protein Csm1 HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 SUPERFAMILY SSF109604 8 80 9.42E-8 T 21-04-2016 HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 PANTHER PTHR36528:SF1 1 756 4.4E-63 T 21-04-2016 HSISS4_RS05040 351a849f5b6da6f795e6fc5d8a0dc80d 756 Pfam PF01966 HD domain 6 80 1.9E-5 T 21-04-2016 IPR006674 HD domain HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 Gene3D G3DSA:3.30.390.30 347 456 7.6E-33 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 SUPERFAMILY SSF51905 2 324 1.59E-35 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PANTHER PTHR22912:SF147 3 147 3.8E-184 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PANTHER PTHR22912:SF147 163 455 3.8E-184 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 289 296 6.1E-7 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 107 116 6.1E-7 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 249 263 6.1E-7 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PANTHER PTHR22912 3 147 3.8E-184 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PANTHER PTHR22912 163 455 3.8E-184 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 SUPERFAMILY SSF55424 335 454 6.53E-30 T 21-04-2016 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 443 5.0E-14 T 21-04-2016 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 319 1.4E-61 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 Gene3D G3DSA:3.50.50.60 2 111 3.8E-15 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 Gene3D G3DSA:3.50.50.60 112 326 3.9E-46 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 2.6E-22 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 2.6E-22 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 2.6E-22 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 2.6E-22 T 21-04-2016 HSISS4_RS05865 2d6d0f23ade4424701e80680719a775e 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 2.6E-22 T 21-04-2016 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 Pfam PF03466 LysR substrate binding domain 125 289 9.8E-22 T 21-04-2016 IPR005119 LysR, substrate-binding HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 SUPERFAMILY SSF53850 121 289 1.48E-19 T 21-04-2016 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 63 1.6E-11 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 Gene3D G3DSA:3.40.190.10 177 259 1.3E-15 T 21-04-2016 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 SUPERFAMILY SSF46785 1 83 1.75E-14 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 Gene3D G3DSA:3.40.190.10 128 176 5.7E-5 T 21-04-2016 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 PANTHER PTHR30126 1 289 5.3E-38 T 21-04-2016 HSISS4_RS06635 ae5489dbf8481bb3290b1d5ec4c8a0d2 291 Gene3D G3DSA:1.10.10.10 1 84 2.2E-19 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 148 156 - T 21-04-2016 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 1 523 44.859 T 21-04-2016 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 SUPERFAMILY SSF52540 70 351 1.04E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 Pfam PF00271 Helicase conserved C-terminal domain 226 334 3.0E-29 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 PANTHER PTHR24031 2 518 8.9E-238 T 21-04-2016 HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 SMART SM00487 20 217 5.6E-65 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 Pfam PF00270 DEAD/DEAH box helicase 26 190 1.1E-51 T 21-04-2016 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 SMART SM00490 253 334 3.0E-35 T 21-04-2016 IPR001650 Helicase, C-terminal HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 PANTHER PTHR24031:SF261 2 518 8.9E-238 T 21-04-2016 HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 Gene3D G3DSA:3.40.50.300 2 206 2.7E-81 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07540 21e37c09ea839af7e94ba25236eacfe9 528 Gene3D G3DSA:3.40.50.300 207 366 1.1E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 21-04-2016 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 Pfam PF01245 Ribosomal protein L19 4 112 2.5E-51 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 4 113 2.0E-49 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 PANTHER PTHR15680 1 115 2.6E-52 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.715 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 SUPERFAMILY SSF50104 1 115 1.0E-46 T 21-04-2016 IPR008991 Translation protein SH3-like domain HSISS4_RS04225 54ba1117ff1839281b3fc47ed11a62e8 115 PIRSF PIRSF002191 1 115 4.0E-50 T 21-04-2016 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 21 264 3.6E-81 T 21-04-2016 IPR014046 Diadenylate cyclase-like HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 SUPERFAMILY SSF143597 51 249 1.28E-65 T 21-04-2016 HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 PANTHER PTHR34185:SF1 1 283 2.5E-98 T 21-04-2016 HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 PIRSF PIRSF004793 14 278 5.3E-84 T 21-04-2016 IPR014046 Diadenylate cyclase-like HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 PANTHER PTHR34185 1 283 2.5E-98 T 21-04-2016 HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 Gene3D G3DSA:3.40.1700.10 121 250 2.3E-52 T 21-04-2016 HSISS4_RS03775 2609570381b2fb63873e5b3748000d7b 283 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 128 245 5.0E-42 T 21-04-2016 IPR003390 DNA integrity scanning protein, DisA, N-terminal HSISS4_RS07240 c04b3292c1245c8167a2822380cf68df 121 SUPERFAMILY SSF82784 19 119 1.57E-12 T 21-04-2016 IPR003718 OsmC/Ohr family HSISS4_RS07240 c04b3292c1245c8167a2822380cf68df 121 Pfam PF02566 OsmC-like protein 30 117 8.2E-8 T 21-04-2016 IPR003718 OsmC/Ohr family HSISS4_RS07240 c04b3292c1245c8167a2822380cf68df 121 Gene3D G3DSA:3.30.300.20 26 119 3.9E-8 T 21-04-2016 IPR015946 K homology domain-like, alpha/beta HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 4 278 21.629 T 21-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 SUPERFAMILY SSF53613 3 276 1.75E-58 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 Pfam PF01256 Carbohydrate kinase 27 270 3.0E-70 T 21-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 213 223 - T 21-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 PANTHER PTHR12592:SF0 1 276 2.0E-56 T 21-04-2016 HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 PANTHER PTHR12592 1 276 2.0E-56 T 21-04-2016 HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 94 104 - T 21-04-2016 IPR017953 Carbohydrate kinase, predicted, conserved site HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 Gene3D G3DSA:3.40.1190.20 4 276 4.7E-73 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS02885 68c2f38f81f34e7829fde801bb88d1ba 278 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 8 274 1.5E-48 T 21-04-2016 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 HSISS4_RS02075 8f22398e086319ba3e8985dede92b5e5 246 Pfam PF02517 CAAX protease self-immunity 102 199 1.8E-16 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 PANTHER PTHR11831:SF4 1 199 1.1E-82 T 21-04-2016 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 PANTHER PTHR11831 1 199 1.1E-82 T 21-04-2016 IPR022801 Ribosomal protein S4/S9 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 ProSitePatterns PS00632 Ribosomal protein S4 signature. 91 115 - T 21-04-2016 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 SMART SM01390 3 92 3.2E-40 T 21-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 3.3E-76 T 21-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 SMART SM00363 93 157 3.3E-20 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 Pfam PF01479 S4 domain 93 140 8.1E-22 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.891 T 21-04-2016 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 Gene3D G3DSA:3.10.290.10 97 192 2.9E-35 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 SUPERFAMILY SSF55174 3 201 1.83E-66 T 21-04-2016 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 Gene3D G3DSA:1.10.1050.10 1 96 3.6E-37 T 21-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HSISS4_RS09590 8d67da8fb37eb6ae12ff529f18c7ef10 203 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 92 3.4E-24 T 21-04-2016 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 PANTHER PTHR11206:SF95 3 421 4.6E-75 T 21-04-2016 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 Pfam PF01554 MatE 13 171 9.4E-26 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 Pfam PF01554 MatE 227 387 1.1E-22 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 TIGRFAM TIGR00797 matE: MATE efflux family protein 13 401 1.0E-59 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 PIRSF PIRSF006603 3 428 1.3E-77 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS09135 ad3546fafe4dfd4de8231139b3a69b35 428 PANTHER PTHR11206 3 421 4.6E-75 T 21-04-2016 HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 SMART SM00382 30 218 2.3E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 PIRSF PIRSF039085 2 246 1.5E-107 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 PANTHER PTHR24220 7 245 1.6E-126 T 21-04-2016 HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 Pfam PF00005 ABC transporter 21 170 5.7E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 SUPERFAMILY SSF52540 5 240 1.94E-75 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 Gene3D G3DSA:3.40.50.300 4 242 6.1E-82 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00830 59205f65b1b71df9b45b284a20f4bb92 246 PANTHER PTHR24220:SF327 7 245 1.6E-126 T 21-04-2016 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 Gene3D G3DSA:3.90.1310.10 166 275 7.4E-30 T 21-04-2016 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 Gene3D G3DSA:3.40.710.10 276 619 4.4E-70 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 PANTHER PTHR30627:SF1 13 655 3.8E-141 T 21-04-2016 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 SUPERFAMILY SSF54184 699 754 2.75E-12 T 21-04-2016 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 SUPERFAMILY SSF54184 637 695 5.23E-13 T 21-04-2016 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 SUPERFAMILY SSF56519 74 267 1.44E-43 T 21-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 Pfam PF00905 Penicillin binding protein transpeptidase domain 295 614 6.0E-71 T 21-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 Pfam PF03793 PASTA domain 699 754 1.5E-9 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 SMART SM00740 694 755 2.3E-15 T 21-04-2016 IPR005543 PASTA domain HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 Pfam PF03717 Penicillin-binding Protein dimerisation domain 77 250 4.5E-26 T 21-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 SUPERFAMILY SSF56601 269 623 2.01E-73 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS08145 5426344eb9ceac814bc4663cbdc52ba3 755 PANTHER PTHR30627 13 655 3.8E-141 T 21-04-2016 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 Gene3D G3DSA:3.10.560.10 81 127 6.5E-11 T 21-04-2016 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 PANTHER PTHR21180 64 230 1.6E-39 T 21-04-2016 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 SMART SM00278 208 227 1.1 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 SMART SM00278 178 197 0.043 T 21-04-2016 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 Gene3D G3DSA:1.10.150.320 162 230 5.1E-23 T 21-04-2016 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 Pfam PF10531 SLBB domain 85 138 5.7E-14 T 21-04-2016 IPR019554 Soluble ligand binding domain HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 Pfam PF12836 Helix-hairpin-helix motif 168 228 1.5E-24 T 21-04-2016 HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 166 229 1.1E-25 T 21-04-2016 IPR004509 Competence protein ComEA, helix-hairpin-helix domain HSISS4_RS07515 8040967527acfb793e3bc640aba9a0ce 231 SUPERFAMILY SSF47781 154 230 3.11E-32 T 21-04-2016 IPR010994 RuvA domain 2-like Reactome: REACT_216 HSISS4_RS09715 b05b17be06e3a0666333e91834cb0ab1 864 PANTHER PTHR38454 1 864 7.5E-88 T 21-04-2016 HSISS4_RS09715 b05b17be06e3a0666333e91834cb0ab1 864 Pfam PF09586 Bacterial membrane protein YfhO 16 841 7.5E-252 T 21-04-2016 IPR018580 Uncharacterised protein family YfhO HSISS4_RS09715 b05b17be06e3a0666333e91834cb0ab1 864 PANTHER PTHR38454:SF1 1 864 7.5E-88 T 21-04-2016 HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1550 1648 1.8E-34 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 2065 2163 1.5E-32 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 708 813 1.2E-12 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 2166 2264 2.5E-32 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1762 1860 6.9E-35 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1208 1313 8.9E-29 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1432 1547 2.1E-22 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 849 971 1.7E-23 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1964 2062 2.8E-34 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 975 1086 1.8E-22 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1090 1205 4.4E-23 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1318 1428 3.0E-23 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 2267 2365 4.1E-31 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1863 1961 8.2E-33 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04225 CshA_fibril_rpt: CshA-type fibril repeat 1651 1759 3.1E-26 T 21-04-2016 IPR026395 CshA-type fibril repeat HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 Pfam PF00746 Gram positive anchor 2508 2542 1.5E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 2514 2547 8.3E-7 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04308 repeat_SSSPR51: surface protein repeat SSSPR-51 2369 2419 1.4E-17 T 21-04-2016 IPR027579 Surface protein repeat SSSPR-51 HSISS4_RS04160 1831c573d0f37e5e5b32977c82297dc3 2547 TIGRFAM TIGR04308 repeat_SSSPR51: surface protein repeat SSSPR-51 2419 2469 5.5E-20 T 21-04-2016 IPR027579 Surface protein repeat SSSPR-51 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 SUPERFAMILY SSF101386 2 89 1.59E-25 T 21-04-2016 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 2 85 8.9E-32 T 21-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 Gene3D G3DSA:1.10.287.1080 28 80 6.6E-5 T 21-04-2016 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 85 17.824 T 21-04-2016 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31|UniPathway: UPA00031 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 7 88 7.5E-17 T 21-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 HSISS4_RS03925 32746345d57d83a65baeafcb3968dea2 104 PANTHER PTHR21256 1 91 1.1E-36 T 21-04-2016 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 Pfam PF01634 ATP phosphoribosyltransferase 55 205 2.0E-51 T 21-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 186 5.5E-64 T 21-04-2016 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 SUPERFAMILY SSF53850 2 201 8.96E-67 T 21-04-2016 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 5 209 58.262 T 21-04-2016 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 Gene3D G3DSA:3.40.190.10 5 144 1.1E-44 T 21-04-2016 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 PANTHER PTHR21403 3 212 9.6E-89 T 21-04-2016 IPR001348 ATP phosphoribosyltransferase HisG GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 PANTHER PTHR21403:SF3 3 212 9.6E-89 T 21-04-2016 HSISS4_RS03890 fbba894eb93ea9ae3f67e8f927aaea25 216 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 145 166 - T 21-04-2016 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17|UniPathway: UPA00031 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 7 144 21.942 T 21-04-2016 IPR011605 NusB antitermination factor GO:0006353 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 Pfam PF01029 NusB family 11 140 1.3E-32 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 Gene3D G3DSA:1.10.940.10 8 142 2.1E-39 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 SUPERFAMILY SSF48013 8 139 6.02E-35 T 21-04-2016 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 PANTHER PTHR11078 1 144 8.2E-42 T 21-04-2016 IPR011605 NusB antitermination factor GO:0006353 HSISS4_RS08370 d192896fb0c02bb18884bd576e6a908d 144 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 8 141 4.4E-38 T 21-04-2016 IPR011605 NusB antitermination factor GO:0006353 HSISS4_RS01160 b72ca9074751cbec296e2ed8a64f5f2f 164 Pfam PF13673 Acetyltransferase (GNAT) domain 22 159 2.0E-10 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS01160 b72ca9074751cbec296e2ed8a64f5f2f 164 PANTHER PTHR10908 1 159 3.0E-29 T 21-04-2016 HSISS4_RS01160 b72ca9074751cbec296e2ed8a64f5f2f 164 Gene3D G3DSA:3.40.630.30 2 159 1.3E-39 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01160 b72ca9074751cbec296e2ed8a64f5f2f 164 SUPERFAMILY SSF55729 2 158 3.66E-24 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05620 a118c476a1ba17cf92d2284bd2f0426b 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 331 5.0E-37 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS05620 a118c476a1ba17cf92d2284bd2f0426b 355 PANTHER PTHR32196:SF30 10 355 6.8E-95 T 21-04-2016 HSISS4_RS05620 a118c476a1ba17cf92d2284bd2f0426b 355 PANTHER PTHR32196 10 355 6.8E-95 T 21-04-2016 HSISS4_RS07895 b0ca8f0fe91792f08bc404210f9890bb 402 Pfam PF01501 Glycosyl transferase family 8 6 232 5.3E-34 T 21-04-2016 IPR002495 Glycosyl transferase, family 8 GO:0016757 HSISS4_RS07895 b0ca8f0fe91792f08bc404210f9890bb 402 SUPERFAMILY SSF53448 6 253 2.45E-57 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07895 b0ca8f0fe91792f08bc404210f9890bb 402 Gene3D G3DSA:3.90.550.10 6 252 2.3E-61 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS02320 5bf6f1c3a7e533fb47b309c5e3278541 106 PIRSF PIRSF021439 1 106 5.2E-37 T 21-04-2016 IPR010377 Initiation control protein YabA GO:0006260 HSISS4_RS02320 5bf6f1c3a7e533fb47b309c5e3278541 106 PANTHER PTHR41240 2 106 2.9E-24 T 21-04-2016 HSISS4_RS02320 5bf6f1c3a7e533fb47b309c5e3278541 106 Pfam PF06156 Protein of unknown function (DUF972) 1 100 4.4E-31 T 21-04-2016 IPR010377 Initiation control protein YabA GO:0006260 HSISS4_RS00575 654efc7d96d9d82211c6c6ce7c99b05e 105 Gene3D G3DSA:1.10.443.10 6 88 4.0E-17 T 21-04-2016 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS00575 654efc7d96d9d82211c6c6ce7c99b05e 105 Pfam PF00589 Phage integrase family 21 87 3.9E-11 T 21-04-2016 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 HSISS4_RS00575 654efc7d96d9d82211c6c6ce7c99b05e 105 SUPERFAMILY SSF56349 5 88 5.59E-16 T 21-04-2016 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 182 1.1E-14 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 9.4E-11 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 9.4E-11 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 9.4E-11 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 9.4E-11 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PANTHER PTHR18901 2 212 2.2E-39 T 21-04-2016 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 SUPERFAMILY SSF56784 2 211 7.03E-45 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 178 8.7E-6 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 Gene3D G3DSA:3.40.50.1000 89 211 9.5E-38 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 Gene3D G3DSA:3.40.50.1000 2 16 9.5E-38 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 Gene3D G3DSA:1.10.150.240 17 81 2.9E-32 T 21-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 184 1.6E-32 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS01775 c95ce7f220a7b3207d4aa7cf500f5279 212 PANTHER PTHR18901:SF34 2 212 2.2E-39 T 21-04-2016 HSISS4_RS04275 0acdf963181ec349977623a032ca1760 608 SUPERFAMILY SSF88713 295 470 2.1E-5 T 21-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HSISS4_RS04275 0acdf963181ec349977623a032ca1760 608 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 21 193 1.5E-25 T 21-04-2016 IPR018695 Protein of unknown function DUF2194 HSISS4_RS04275 0acdf963181ec349977623a032ca1760 608 Pfam PF09960 Uncharacterised protein conserved in bacteria (DUF2194) 208 595 7.2E-141 T 21-04-2016 IPR018695 Protein of unknown function DUF2194 HSISS4_RS04275 0acdf963181ec349977623a032ca1760 608 Gene3D G3DSA:3.20.20.370 296 446 2.7E-4 T 21-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HSISS4_RS09480 d41eda926afabd7837733c18f0ecb6ad 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 8.5E-19 T 21-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09480 d41eda926afabd7837733c18f0ecb6ad 60 PANTHER PTHR35534 1 60 3.1E-26 T 21-04-2016 HSISS4_RS09480 d41eda926afabd7837733c18f0ecb6ad 60 SUPERFAMILY SSF57829 2 54 4.15E-16 T 21-04-2016 IPR011332 Zinc-binding ribosomal protein GO:0006412 HSISS4_RS09480 d41eda926afabd7837733c18f0ecb6ad 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.158 T 21-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09480 d41eda926afabd7837733c18f0ecb6ad 60 Pfam PF01783 Ribosomal L32p protein family 2 54 1.1E-18 T 21-04-2016 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 HSISS4_RS06035 a3b455ec242b66cc5d3195103e38c5e4 303 Gene3D G3DSA:1.10.260.40 2 78 1.6E-12 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06035 a3b455ec242b66cc5d3195103e38c5e4 303 Pfam PF12844 Helix-turn-helix domain 10 70 1.9E-7 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06035 a3b455ec242b66cc5d3195103e38c5e4 303 SUPERFAMILY SSF47413 4 73 7.7E-11 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS02515 85ca3f521310f5d30d05f66176154265 517 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 10 491 1.6E-185 T 21-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HSISS4_RS02515 85ca3f521310f5d30d05f66176154265 517 PANTHER PTHR30047 10 517 1.3E-217 T 21-04-2016 HSISS4_RS02515 85ca3f521310f5d30d05f66176154265 517 PANTHER PTHR30047:SF2 10 517 1.3E-217 T 21-04-2016 HSISS4_RS02515 85ca3f521310f5d30d05f66176154265 517 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 48 490 4.0E-160 T 21-04-2016 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 SUPERFAMILY SSF54211 1 109 6.57E-33 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 Pfam PF00825 Ribonuclease P 1 105 1.2E-30 T 21-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 107 7.7E-27 T 21-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 PANTHER PTHR33992 1 111 2.0E-32 T 21-04-2016 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 Gene3D G3DSA:3.30.230.10 1 109 7.5E-37 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 109 18.522 T 21-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 8 105 2.0E-50 T 21-04-2016 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 HSISS4_RS08795 6e2384b3122e7071d0898441fbee9f76 111 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 50 64 - T 21-04-2016 IPR020539 Ribonuclease P, conserved site GO:0004526 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 Pfam PF00551 Formyl transferase 3 176 3.6E-49 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 SUPERFAMILY SSF53328 3 178 3.53E-54 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 Gene3D G3DSA:3.40.50.170 3 179 4.5E-64 T 21-04-2016 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 PANTHER PTHR10520 3 179 3.6E-80 T 21-04-2016 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 178 4.8E-61 T 21-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 HSISS4_RS00235 fd3640264841dd4ab74a0067be7f2ddd 184 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 4 182 29.169 T 21-04-2016 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|UniPathway: UPA00074 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Gene3D G3DSA:3.90.400.10 105 169 3.0E-27 T 21-04-2016 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 SUPERFAMILY SSF51011 465 534 2.7E-10 T 21-04-2016 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Pfam PF16657 Maltogenic Amylase, C-terminal domain 465 522 7.5E-7 T 21-04-2016 IPR032091 Maltogenic Amylase, C-terminal HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 SMART SM00642 13 402 6.6E-148 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 SUPERFAMILY SSF51445 4 461 2.27E-144 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Pfam PF00128 Alpha amylase, catalytic domain 28 359 2.4E-121 T 21-04-2016 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357:SF142 440 499 2.1E-226 T 21-04-2016 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357:SF142 1 379 2.1E-226 T 21-04-2016 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357:SF142 395 407 2.1E-226 T 21-04-2016 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Gene3D G3DSA:3.20.20.80 3 104 1.1E-116 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Gene3D G3DSA:3.20.20.80 170 462 1.1E-116 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 Gene3D G3DSA:2.60.40.1180 465 535 1.3E-12 T 21-04-2016 IPR013780 Glycosyl hydrolase, all-beta HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357 440 499 2.1E-226 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357 1 379 2.1E-226 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS06395 ba5eb1b7644cd060d1e30a7432682b9a 536 PANTHER PTHR10357 395 407 2.1E-226 T 21-04-2016 IPR015902 Glycoside hydrolase, family 13 GO:0003824 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Gene3D G3DSA:3.30.470.20 206 447 4.7E-96 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 323 1.2E-75 T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 SUPERFAMILY SSF52440 1 113 1.8E-48 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 SUPERFAMILY SSF56059 83 353 2.47E-71 T 21-04-2016 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 PANTHER PTHR18866 1 456 3.0E-296 T 21-04-2016 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Pfam PF02785 Biotin carboxylase C-terminal domain 337 444 1.4E-37 T 21-04-2016 IPR005482 Biotin carboxylase, C-terminal HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 21-04-2016 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Gene3D G3DSA:3.30.1490.20 130 202 2.1E-30 T 21-04-2016 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 3.2E-205 T 21-04-2016 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.6E-45 T 21-04-2016 IPR005481 Biotin carboxylase-like, N-terminal domain HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 Gene3D G3DSA:3.40.50.20 1 129 1.3E-49 T 21-04-2016 IPR016185 Pre-ATP-grasp domain HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 SMART SM00878 337 444 4.9E-57 T 21-04-2016 IPR005482 Biotin carboxylase, C-terminal HSISS4_RS01830 99ac5ad0eedd9c57887d5d50d4826fdc 456 SUPERFAMILY SSF51246 332 445 2.88E-40 T 21-04-2016 IPR011054 Rudiment single hybrid motif HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PANTHER PTHR24423 90 315 1.2E-88 T 21-04-2016 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PANTHER PTHR24423:SF557 90 315 1.2E-88 T 21-04-2016 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 SMART SM00387 213 319 4.3E-18 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 214 318 6.4E-17 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 Gene3D G3DSA:3.30.565.10 172 315 1.9E-26 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 316 8.7E-6 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 279 297 8.7E-6 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 245 259 8.7E-6 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 263 273 8.7E-6 T 21-04-2016 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 HSISS4_RS06145 a53f807facd126bc4b9bd09380952b8d 323 SUPERFAMILY SSF55874 171 315 2.1E-26 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 SUPERFAMILY SSF55729 168 240 2.33E-27 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 PANTHER PTHR36174 1 404 4.3E-119 T 21-04-2016 HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 Gene3D G3DSA:3.40.630.30 1 168 3.1E-62 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 SUPERFAMILY SSF55729 1 175 1.06E-44 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 PANTHER PTHR36174:SF1 1 404 4.3E-119 T 21-04-2016 HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 Pfam PF02388 FemAB family 8 395 2.2E-132 T 21-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 Gene3D G3DSA:3.40.630.30 169 239 7.5E-38 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 Gene3D G3DSA:3.40.630.30 297 371 7.5E-38 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04400 70d7b04540bd70525666fdc5961ee0c8 404 SUPERFAMILY SSF55729 297 390 2.33E-27 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 303 29.432 T 21-04-2016 IPR003802 Sporulation regulator WhiA GO:0043937 HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 5 301 4.3E-109 T 21-04-2016 HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 Pfam PF02650 WhiA C-terminal HTH domain 218 300 5.8E-29 T 21-04-2016 IPR023054 Sporulation regulator WhiA, C-terminal HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 Gene3D G3DSA:3.10.28.10 118 210 8.9E-7 T 21-04-2016 IPR027434 Homing endonuclease GO:0004519 HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 17 99 2.1E-30 T 21-04-2016 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 SUPERFAMILY SSF55608 117 217 1.53E-14 T 21-04-2016 IPR027434 Homing endonuclease GO:0004519 HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 PANTHER PTHR37307 2 303 3.6E-105 T 21-04-2016 HSISS4_RS05530 2d49bb1bfb7da46a9459b26b10ba1f2f 303 Pfam PF14527 WhiA LAGLIDADG-like domain 122 214 1.6E-30 T 21-04-2016 HSISS4_RS01755 535434af75ab6e8392517e0f92946eb6 258 PANTHER PTHR33602:SF1 1 222 3.3E-34 T 21-04-2016 HSISS4_RS01755 535434af75ab6e8392517e0f92946eb6 258 Hamap MF_01114 Regulatory protein RecX [recX]. 36 203 16.251 T 21-04-2016 IPR003783 Regulatory protein RecX GO:0006282 HSISS4_RS01755 535434af75ab6e8392517e0f92946eb6 258 Pfam PF02631 RecX family 81 198 2.9E-21 T 21-04-2016 IPR003783 Regulatory protein RecX GO:0006282 HSISS4_RS01755 535434af75ab6e8392517e0f92946eb6 258 Pfam PF02631 RecX family 202 255 5.2E-5 T 21-04-2016 IPR003783 Regulatory protein RecX GO:0006282 HSISS4_RS01755 535434af75ab6e8392517e0f92946eb6 258 PANTHER PTHR33602 1 222 3.3E-34 T 21-04-2016 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 Pfam PF00210 Ferritin-like domain 27 169 2.2E-26 T 21-04-2016 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PANTHER PTHR30295:SF6 6 170 1.1E-42 T 21-04-2016 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PIRSF PIRSF005900 4 172 5.3E-39 T 21-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 ProSitePatterns PS00818 Dps protein family signature 1. 47 63 - T 21-04-2016 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PANTHER PTHR30295 6 170 1.1E-42 T 21-04-2016 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 SUPERFAMILY SSF47240 5 170 5.54E-38 T 21-04-2016 IPR009078 Ferritin-like superfamily HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 71 87 5.6E-13 T 21-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 144 162 5.6E-13 T 21-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 47 63 5.6E-13 T 21-04-2016 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 HSISS4_RS03590 f5057d9c908a1c11647b111c8ac70ed1 173 Gene3D G3DSA:1.20.1260.10 17 170 1.2E-47 T 21-04-2016 IPR012347 Ferritin-related HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 Gene3D G3DSA:3.40.720.10 255 571 2.9E-36 T 21-04-2016 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 PANTHER PTHR10342 226 587 5.3E-104 T 21-04-2016 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 PANTHER PTHR10342 632 656 5.3E-104 T 21-04-2016 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 PANTHER PTHR10342:SF214 226 587 5.3E-104 T 21-04-2016 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 PANTHER PTHR10342:SF214 632 656 5.3E-104 T 21-04-2016 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 SUPERFAMILY SSF53649 252 662 7.2E-71 T 21-04-2016 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 Pfam PF00884 Sulfatase 254 558 6.7E-34 T 21-04-2016 IPR000917 Sulfatase, N-terminal GO:0008152|GO:0008484 HSISS4_RS02995 5c0f37e742130cba1799b79c33f4ab79 728 PIRSF PIRSF005091 1 648 8.4E-172 T 21-04-2016 IPR012160 Lipoteichoic acid synthase-like KEGG: 00440+2.7.8.-|KEGG: 00513+2.7.8.-|KEGG: 00540+2.7.8.-|KEGG: 00564+2.7.8.-|KEGG: 00600+2.7.8.-|KEGG: 00770+2.7.8.-|UniPathway: UPA00556 HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 PANTHER PTHR33370 2 72 7.6E-46 T 21-04-2016 HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 5.0E-28 T 21-04-2016 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 SUPERFAMILY SSF50249 2 71 4.63E-28 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 Gene3D G3DSA:2.40.50.140 2 72 1.1E-39 T 21-04-2016 IPR012340 Nucleic acid-binding, OB-fold HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 SMART SM00316 4 72 2.2E-6 T 21-04-2016 IPR022967 RNA-binding domain, S1 HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.723 T 21-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HSISS4_RS09240 afbaf50b4547b2a94fdd5680c3a075d5 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 3.4E-38 T 21-04-2016 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 SUPERFAMILY SSF53756 182 500 5.23E-36 T 21-04-2016 HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 Gene3D G3DSA:3.40.50.2000 312 461 1.1E-14 T 21-04-2016 HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 PANTHER PTHR12526 203 502 3.9E-27 T 21-04-2016 HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 Hamap MF_01472 Glycosyltransferase Gtf1 [gtf1]. 2 500 36.046 T 21-04-2016 IPR014267 Glycosyltransferase Gtf1 GO:0016757 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.- HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 TIGRFAM TIGR02918 TIGR02918: accessory Sec system glycosylation protein GtfA 1 500 2.4E-232 T 21-04-2016 IPR014267 Glycosyltransferase Gtf1 GO:0016757 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.- HSISS4_RS06735 bb3be9f7715f820f2a4e79e65e9b4b5a 502 Pfam PF13692 Glycosyl transferases group 1 323 466 9.0E-19 T 21-04-2016 HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 PIRSF PIRSF019455 1 128 3.3E-41 T 21-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 Gene3D G3DSA:1.10.10.10 1 74 3.5E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 PANTHER PTHR34134:SF1 1 127 1.8E-33 T 21-04-2016 HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 Pfam PF03965 Penicillinase repressor 3 117 4.0E-33 T 21-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 PANTHER PTHR34134 1 127 1.8E-33 T 21-04-2016 HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 SUPERFAMILY SSF46785 1 119 5.86E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05145 b9c3ef62afee64746e3ab795a30ab871 131 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 2 131 1.2E-50 T 21-04-2016 IPR014071 Copper transport repressor CopY/TcrY HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 SMART SM00347 29 131 1.5E-15 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 SUPERFAMILY SSF46785 11 146 1.04E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 PANTHER PTHR18964 1 147 2.1E-21 T 21-04-2016 HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 Gene3D G3DSA:1.10.10.10 16 146 6.6E-25 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 Pfam PF01047 MarR family 36 92 2.3E-12 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS00900 3416fc81f5a047c8e8600e9584030183 147 PANTHER PTHR18964:SF125 1 147 2.1E-21 T 21-04-2016 HSISS4_RS08150 4e6d87f9f6dab3c9c43ae9bd7ab291d3 106 Hamap MF_00910 Cell division protein FtsL [ftsL]. 22 106 13.429 T 21-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 HSISS4_RS08150 4e6d87f9f6dab3c9c43ae9bd7ab291d3 106 Pfam PF04977 Septum formation initiator 32 102 2.7E-7 T 21-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 HSISS4_RS08150 4e6d87f9f6dab3c9c43ae9bd7ab291d3 106 PANTHER PTHR41300 10 106 5.4E-15 T 21-04-2016 HSISS4_RS08150 4e6d87f9f6dab3c9c43ae9bd7ab291d3 106 PANTHER PTHR41300:SF1 10 106 5.4E-15 T 21-04-2016 HSISS4_RS08150 4e6d87f9f6dab3c9c43ae9bd7ab291d3 106 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 24 105 8.3E-15 T 21-04-2016 IPR011922 Cell division protein FtsL GO:0007049|GO:0016021|GO:0051301 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 PANTHER PTHR30614:SF11 1 213 8.1E-82 T 21-04-2016 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 Gene3D G3DSA:1.10.3720.10 8 210 8.9E-52 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 PANTHER PTHR30614 1 213 8.1E-82 T 21-04-2016 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 SUPERFAMILY SSF161098 10 198 1.14E-45 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 8 105 1.6E-29 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS05475 1823ba8ece1281b7abcbb4ddcf56f4a9 213 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 209 2.6E-25 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 Gene3D G3DSA:3.20.70.20 141 702 1.5E-185 T 21-04-2016 HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 132 721 1.1E-180 T 21-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 PANTHER PTHR21075 7 727 3.7E-274 T 21-04-2016 HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 Pfam PF03477 ATP cone domain 15 106 6.4E-20 T 21-04-2016 IPR005144 ATP-cone domain HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 ProSitePatterns PS00850 Glycine radical domain signature. 692 700 - T 21-04-2016 IPR019777 Formate C-acetyltransferase glycine radical, conserved site HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 132 721 9.7E-183 T 21-04-2016 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.17.4.2|KEGG: 00240+1.17.4.2|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 HSISS4_RS09430 313c9d78385584c4970e9252d90ed8cc 734 SUPERFAMILY SSF51998 137 703 3.57E-194 T 21-04-2016 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 Hamap MF_01575 UPF0398 protein . 1 171 36.233 T 21-04-2016 IPR010697 Protein of unknown function DUF1273 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 SUPERFAMILY SSF102405 1 171 1.1E-56 T 21-04-2016 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 Gene3D G3DSA:3.40.50.450 1 171 3.3E-60 T 21-04-2016 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 PANTHER PTHR38440 2 171 3.1E-41 T 21-04-2016 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 PIRSF PIRSF021290 1 171 3.7E-70 T 21-04-2016 IPR010697 Protein of unknown function DUF1273 HSISS4_RS01120 9f90e3e23b7646d93721c3e72b3ccf63 171 Pfam PF06908 Protein of unknown function (DUF1273) 4 165 7.0E-64 T 21-04-2016 IPR010697 Protein of unknown function DUF1273 HSISS4_RS05880 028a974554ea2e37fb0cb333f2e2c373 285 PANTHER PTHR10534 1 252 2.7E-31 T 21-04-2016 IPR004625 Pyridoxine kinase GO:0008478|GO:0009443 KEGG: 00750+2.7.1.35|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HSISS4_RS05880 028a974554ea2e37fb0cb333f2e2c373 285 Pfam PF08543 Phosphomethylpyrimidine kinase 70 250 5.0E-13 T 21-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 HSISS4_RS05880 028a974554ea2e37fb0cb333f2e2c373 285 SUPERFAMILY SSF53613 1 270 1.37E-45 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS05880 028a974554ea2e37fb0cb333f2e2c373 285 PANTHER PTHR10534:SF0 1 252 2.7E-31 T 21-04-2016 HSISS4_RS05880 028a974554ea2e37fb0cb333f2e2c373 285 Gene3D G3DSA:3.40.1190.20 1 257 1.4E-48 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 Gene3D G3DSA:2.40.50.100 87 164 1.1E-26 T 21-04-2016 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 PANTHER PTHR23151:SF64 1 164 2.2E-33 T 21-04-2016 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 120 137 - T 21-04-2016 IPR001882 Biotin-binding site HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 SUPERFAMILY SSF51230 90 163 9.95E-22 T 21-04-2016 IPR011053 Single hybrid motif HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 93 106 2.7E-13 T 21-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 125 138 2.7E-13 T 21-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 110 124 2.7E-13 T 21-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 PANTHER PTHR23151 1 164 2.2E-33 T 21-04-2016 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 164 2.3E-40 T 21-04-2016 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 UniPathway: UPA00094 HSISS4_RS01820 580f9621f65507c6bb036e12eab010d0 164 Pfam PF00364 Biotin-requiring enzyme 90 163 5.4E-20 T 21-04-2016 IPR000089 Biotin/lipoyl attachment HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 7 805 0.0 T 21-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Gene3D G3DSA:3.30.1360.40 234 330 2.5E-35 T 21-04-2016 IPR024946 Arginine repressor C-terminal-like domain HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 PANTHER PTHR10169 2 775 0.0 T 21-04-2016 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 809 29.118 T 21-04-2016 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 SUPERFAMILY SSF101904 497 818 1.7E-106 T 21-04-2016 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 30 470 1.6E-159 T 21-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 759 805 1.9E-10 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 611 654 4.8E-11 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 552 599 1.2E-11 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 548 2.2E-10 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 708 756 7.9E-13 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 659 704 1.9E-12 T 21-04-2016 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Gene3D G3DSA:2.120.10.90 494 805 1.1E-121 T 21-04-2016 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 PANTHER PTHR10169:SF48 2 775 0.0 T 21-04-2016 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 SUPERFAMILY SSF56719 28 484 1.83E-178 T 21-04-2016 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 SMART SM00434 9 462 1.3E-290 T 21-04-2016 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Gene3D G3DSA:3.90.199.10 331 396 1.2E-122 T 21-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HSISS4_RS05855 ca2adfaee1d4f3276826589737f99151 822 Gene3D G3DSA:3.90.199.10 28 233 1.2E-122 T 21-04-2016 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 PANTHER PTHR23117 1 209 2.6E-94 T 21-04-2016 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 Pfam PF00625 Guanylate kinase 7 186 4.9E-53 T 21-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 36.825 T 21-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 4.8E-72 T 21-04-2016 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 SMART SM00072 4 187 1.7E-72 T 21-04-2016 IPR008145 Guanylate kinase/L-type calcium channel beta subunit HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 PANTHER PTHR23117:SF13 1 209 2.6E-94 T 21-04-2016 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 SUPERFAMILY SSF52540 4 189 1.8E-66 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 Gene3D G3DSA:3.30.63.10 35 87 5.9E-28 T 21-04-2016 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 21-04-2016 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 Gene3D G3DSA:3.40.50.300 3 27 1.5E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06945 0c5fefcb6f704594bc858e467372c6b3 209 Gene3D G3DSA:3.40.50.300 88 203 1.5E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09575 5f741a69d503e016bea161b71a09732b 179 Gene3D G3DSA:1.10.357.10 4 177 2.6E-18 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS09575 5f741a69d503e016bea161b71a09732b 179 SUPERFAMILY SSF46689 5 68 1.6E-12 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS09575 5f741a69d503e016bea161b71a09732b 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.3E-5 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS09575 5f741a69d503e016bea161b71a09732b 179 PANTHER PTHR30055:SF55 1 177 2.5E-33 T 21-04-2016 HSISS4_RS09575 5f741a69d503e016bea161b71a09732b 179 PANTHER PTHR30055 1 177 2.5E-33 T 21-04-2016 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 PANTHER PTHR33360:SF2 3 146 7.0E-79 T 21-04-2016 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 Gene3D G3DSA:3.30.70.1290 1 133 1.0E-56 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 SUPERFAMILY SSF143422 4 130 1.7E-46 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 Pfam PF01797 Transposase IS200 like 13 130 1.3E-37 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 PANTHER PTHR33360 3 146 7.0E-79 T 21-04-2016 HSISS4_RS06535 472a2175338d968eb6c72cf4f5e469a5 157 SMART SM01321 12 130 1.5E-42 T 21-04-2016 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 685 743 4.3E-13 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 540 630 4.1E-10 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 403 470 4.8E-12 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 471 539 2.6E-10 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Pfam PF01473 Putative cell wall binding repeat 220 231 0.37 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Pfam PF01473 Putative cell wall binding repeat 371 388 0.31 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Pfam PF01473 Putative cell wall binding repeat 664 681 0.81 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 SUPERFAMILY SSF69360 358 505 3.3E-20 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 380 443 1.4E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 536 593 2.0E-16 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 673 730 1.3E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 159 220 2.1E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 472 533 1.2E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 223 282 3.5E-17 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 SUPERFAMILY SSF69360 145 317 4.84E-24 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.20.120.10 275 316 6.5E-6 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 SUPERFAMILY SSF69360 580 742 6.34E-24 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 631 684 5.6E-14 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 151 188 1.2E-7 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 358 402 3.6E-8 T 21-04-2016 HSISS4_RS06595 f73ba91f84efa44e1d5f809c40717253 746 Gene3D G3DSA:2.10.270.10 202 274 1.9E-10 T 21-04-2016 HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 Gene3D G3DSA:1.10.10.10 5 67 4.4E-27 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 PANTHER PTHR34134:SF1 1 128 3.1E-24 T 21-04-2016 HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 TIGRFAM TIGR02698 CopY_TcrY: copper transport repressor, CopY/TcrY family 3 130 7.0E-47 T 21-04-2016 IPR014071 Copper transport repressor CopY/TcrY HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 PIRSF PIRSF019455 1 129 1.6E-40 T 21-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 SUPERFAMILY SSF46785 1 116 2.69E-26 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 Pfam PF03965 Penicillinase repressor 4 116 1.3E-34 T 21-04-2016 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 HSISS4_RS07635 e2a859527fc78295cd41b4e0a9bc261e 143 PANTHER PTHR34134 1 128 3.1E-24 T 21-04-2016 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 Pfam PF04055 Radical SAM superfamily 33 125 4.5E-11 T 21-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 PANTHER PTHR11228 1 228 6.0E-42 T 21-04-2016 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 PANTHER PTHR11228:SF6 1 228 6.0E-42 T 21-04-2016 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 Gene3D G3DSA:3.20.20.70 25 125 8.6E-14 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 Pfam PF13394 4Fe-4S single cluster domain 31 113 7.6E-10 T 21-04-2016 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 PIRSF PIRSF000370 7 238 2.3E-47 T 21-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 8 238 2.6E-101 T 21-04-2016 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 9 235 32.599 T 21-04-2016 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703|UniPathway: UPA00391 HSISS4_RS05560 31b737b4d48d1498dc9b5e3369520e76 238 SUPERFAMILY SSF102114 30 142 7.85E-13 T 21-04-2016 HSISS4_RS05735 a6c3bf8abacbab746a4ec8e72decf326 415 PANTHER PTHR13285 16 408 6.2E-55 T 21-04-2016 HSISS4_RS05735 a6c3bf8abacbab746a4ec8e72decf326 415 TIGRFAM TIGR04091 LTA_dltB: D-alanyl-lipoteichoic acid biosynthesis protein DltB 13 407 2.6E-162 T 21-04-2016 IPR024024 D-alanyl transfer protein DltB UniPathway: UPA00556 HSISS4_RS05735 a6c3bf8abacbab746a4ec8e72decf326 415 PIRSF PIRSF016636 16 408 1.1E-73 T 21-04-2016 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB HSISS4_RS05735 a6c3bf8abacbab746a4ec8e72decf326 415 PIRSF PIRSF500216 10 412 5.5E-177 T 21-04-2016 IPR024024 D-alanyl transfer protein DltB UniPathway: UPA00556 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 Gene3D G3DSA:3.40.190.10 116 210 1.7E-25 T 21-04-2016 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 Gene3D G3DSA:3.40.190.10 31 115 2.1E-39 T 21-04-2016 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 Gene3D G3DSA:3.40.190.10 220 255 2.1E-39 T 21-04-2016 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 SMART SM00079 35 259 0.0012 T 21-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 SMART SM00062 35 257 1.7E-59 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 SUPERFAMILY SSF53850 1 255 3.2E-70 T 21-04-2016 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 36 254 2.6E-60 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 PANTHER PTHR30614:SF15 26 259 2.5E-66 T 21-04-2016 HSISS4_RS07160 c4cac458d7155b1a3a904d532b1fbb62 264 PANTHER PTHR30614 26 259 2.5E-66 T 21-04-2016 HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 2 238 27.442 T 21-04-2016 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 PRINTS PR00701 60kDa inner membrane protein signature 117 140 1.6E-7 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 PRINTS PR00701 60kDa inner membrane protein signature 201 224 1.6E-7 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 PANTHER PTHR12428 55 246 7.7E-51 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 53 234 3.0E-56 T 21-04-2016 IPR028055 Membrane insertase YidC/Oxa1, C-terminal HSISS4_RS08790 1cf60ee75f16c6ad1670639003d7c1d7 268 Pfam PF02096 60Kd inner membrane protein 55 234 1.9E-49 T 21-04-2016 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 Pfam PF06144 DNA polymerase III, delta subunit 20 192 5.9E-48 T 21-04-2016 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 PANTHER PTHR34388 1 342 1.2E-50 T 21-04-2016 HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 Gene3D G3DSA:3.40.50.300 2 140 2.0E-6 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 SUPERFAMILY SSF48019 216 340 2.55E-18 T 21-04-2016 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: REACT_152|Reactome: REACT_1538|Reactome: REACT_216|Reactome: REACT_22172|Reactome: REACT_383 HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 SUPERFAMILY SSF52540 13 210 1.06E-9 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03575 7b7b359dc913124d1ed995748827a715 344 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 17 340 4.2E-72 T 21-04-2016 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PANTHER PTHR31964 1 148 2.4E-34 T 21-04-2016 HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PRINTS PR01438 Universal stress protein signature 5 23 5.8E-17 T 21-04-2016 IPR006015 Universal stress protein A HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PRINTS PR01438 Universal stress protein signature 104 116 5.8E-17 T 21-04-2016 IPR006015 Universal stress protein A HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PRINTS PR01438 Universal stress protein signature 122 144 5.8E-17 T 21-04-2016 IPR006015 Universal stress protein A HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 SUPERFAMILY SSF52402 5 146 6.95E-32 T 21-04-2016 HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 Gene3D G3DSA:3.40.50.620 5 144 7.3E-38 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 Pfam PF00582 Universal stress protein family 5 144 1.9E-33 T 21-04-2016 IPR006016 UspA GO:0006950 HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PANTHER PTHR31964:SF45 1 148 2.4E-34 T 21-04-2016 HSISS4_RS07920 b5b0a692ba1087bd4207e73f21ddf83f 150 PIRSF PIRSF006276 1 147 2.8E-19 T 21-04-2016 IPR006015 Universal stress protein A HSISS4_RS02185 9c849ea88d3627c44d54488874c5d6e7 292 Gene3D G3DSA:3.20.20.370 99 249 3.9E-32 T 21-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HSISS4_RS02185 9c849ea88d3627c44d54488874c5d6e7 292 PANTHER PTHR34216:SF3 12 292 1.1E-55 T 21-04-2016 HSISS4_RS02185 9c849ea88d3627c44d54488874c5d6e7 292 PANTHER PTHR34216 12 292 1.1E-55 T 21-04-2016 HSISS4_RS02185 9c849ea88d3627c44d54488874c5d6e7 292 SUPERFAMILY SSF88713 90 272 5.28E-40 T 21-04-2016 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 HSISS4_RS02185 9c849ea88d3627c44d54488874c5d6e7 292 Pfam PF01522 Polysaccharide deacetylase 128 247 1.7E-29 T 21-04-2016 IPR002509 NodB homology domain GO:0005975|GO:0016810 HSISS4_RS04940 fdabe77b624f997739f9f7d0800acd78 206 SUPERFAMILY SSF116734 20 176 9.65E-23 T 21-04-2016 HSISS4_RS04940 fdabe77b624f997739f9f7d0800acd78 206 Pfam PF01420 Type I restriction modification DNA specificity domain 20 175 1.5E-9 T 21-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HSISS4_RS06015 d43e3d8d45f02f4a95f7bb73541f0404 179 Pfam PF06271 RDD family 17 170 3.7E-12 T 21-04-2016 IPR010432 RDD HSISS4_RS06230 9ea08cca5cbb81a47bf3e507441954ee 461 PANTHER PTHR11785 14 460 2.9E-124 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS06230 9ea08cca5cbb81a47bf3e507441954ee 461 PIRSF PIRSF006060 6 460 2.0E-81 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS06230 9ea08cca5cbb81a47bf3e507441954ee 461 PANTHER PTHR11785:SF342 14 460 2.9E-124 T 21-04-2016 HSISS4_RS06230 9ea08cca5cbb81a47bf3e507441954ee 461 Pfam PF13520 Amino acid permease 20 429 9.3E-50 T 21-04-2016 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 166 2.1E-27 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Gene3D G3DSA:3.90.950.20 259 418 2.8E-52 T 21-04-2016 IPR008136 CinA, C-terminal HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 SUPERFAMILY SSF142433 259 417 2.62E-46 T 21-04-2016 IPR008136 CinA, C-terminal HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 272 414 1.9E-36 T 21-04-2016 IPR008136 CinA, C-terminal HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 SMART SM00852 4 172 6.5E-37 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Pfam PF02464 Competence-damaged protein 264 416 3.4E-47 T 21-04-2016 IPR008136 CinA, C-terminal HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 422 160.558 T 21-04-2016 IPR008135 Competence-induced protein CinA HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Gene3D G3DSA:3.40.980.10 1 102 9.5E-36 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Gene3D G3DSA:3.40.980.10 144 170 9.5E-36 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 Pfam PF00994 Probable molybdopterin binding domain 5 170 2.6E-33 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 PANTHER PTHR13939 1 422 1.5E-171 T 21-04-2016 HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 417 6.5E-117 T 21-04-2016 IPR008135 Competence-induced protein CinA HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 PIRSF PIRSF006728 1 422 9.0E-143 T 21-04-2016 IPR008135 Competence-induced protein CinA HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 PANTHER PTHR13939:SF0 1 422 1.5E-171 T 21-04-2016 HSISS4_RS00340 b173c1a7d508bb23f8f3cc7f2b85ad0c 422 SUPERFAMILY SSF53218 1 204 2.62E-39 T 21-04-2016 IPR001453 MoaB/Mog domain HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290:SF10 330 388 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290:SF10 1 311 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290:SF10 404 631 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 Gene3D G3DSA:3.90.76.10 41 207 2.6E-39 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 SUPERFAMILY SSF53850 27 591 2.71E-78 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 Gene3D G3DSA:3.40.190.10 208 339 7.7E-18 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 521 4.9E-50 T 21-04-2016 IPR000914 Solute-binding protein family 5 domain HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 80 102 - T 21-04-2016 IPR023765 Solute-binding protein family 5, conserved site HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290 330 388 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290 1 311 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 PANTHER PTHR30290 404 631 5.2E-136 T 21-04-2016 HSISS4_RS07005 ca2157fc942858f4d6e4e8a229ba156a 656 Gene3D G3DSA:3.10.105.10 340 583 1.1E-30 T 21-04-2016 HSISS4_RS05125 c6beb2bce3d6060d76c70984fe96bde9 254 Pfam PF01048 Phosphorylase superfamily 35 232 1.1E-31 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS05125 c6beb2bce3d6060d76c70984fe96bde9 254 SUPERFAMILY SSF53167 30 252 2.62E-52 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS05125 c6beb2bce3d6060d76c70984fe96bde9 254 Gene3D G3DSA:3.40.50.1580 30 251 2.1E-50 T 21-04-2016 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 SUPERFAMILY SSF53383 1 392 4.62E-111 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 Gene3D G3DSA:3.40.640.10 45 274 1.7E-73 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 199 222 2.0E-11 T 21-04-2016 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 163 187 2.0E-11 T 21-04-2016 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 116 137 2.0E-11 T 21-04-2016 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 230 254 2.0E-11 T 21-04-2016 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 Gene3D G3DSA:3.90.1150.10 275 393 7.4E-43 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PANTHER PTHR11751:SF306 14 393 9.6E-149 T 21-04-2016 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 Pfam PF00155 Aminotransferase class I and II 32 387 1.8E-71 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 21-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HSISS4_RS05595 c007a20e6ee00d7a5fa29a82cfdd6694 393 PANTHER PTHR11751 14 393 9.6E-149 T 21-04-2016 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 8 268 1.2E-64 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 SUPERFAMILY SSF56784 3 271 5.38E-70 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 268 2.4E-66 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 PANTHER PTHR10000 6 273 3.9E-72 T 21-04-2016 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 PANTHER PTHR10000:SF16 6 273 3.9E-72 T 21-04-2016 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 Gene3D G3DSA:3.40.50.1000 188 272 1.4E-58 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 Gene3D G3DSA:3.40.50.1000 2 78 1.4E-58 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 8 241 3.8E-32 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 Gene3D G3DSA:3.30.1240.10 90 187 1.2E-11 T 21-04-2016 HSISS4_RS02345 c00ea91833a9025ee9d8052cc5473c16 273 ProSitePatterns PS01229 Hypothetical cof family signature 2. 222 244 - T 21-04-2016 HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 SUPERFAMILY SSF52540 288 316 9.09E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 SUPERFAMILY SSF52540 345 525 9.09E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 SUPERFAMILY SSF52540 1 201 9.09E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 551 1.3E-167 T 21-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 PANTHER PTHR11059 2 554 3.6E-165 T 21-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 Gene3D G3DSA:3.40.50.300 376 506 2.8E-7 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 Gene3D G3DSA:3.40.50.300 1 208 3.9E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 510 1.1E-20 T 21-04-2016 IPR003395 RecF/RecN/SMC, N-terminal HSISS4_RS04080 73c716721471a24a52cc2a4ae0b89f54 556 PIRSF PIRSF003128 1 555 1.8E-174 T 21-04-2016 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 PANTHER PTHR10245 4 162 8.4E-14 T 21-04-2016 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 Pfam PF00717 Peptidase S24-like 145 205 4.9E-12 T 21-04-2016 IPR019759 Peptidase S24/S26A/S26B HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 Pfam PF01381 Helix-turn-helix 7 61 1.6E-16 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 SMART SM00530 6 61 9.5E-17 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 SUPERFAMILY SSF47413 2 67 4.02E-17 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 SUPERFAMILY SSF51306 106 224 5.36E-25 T 21-04-2016 IPR015927 Peptidase S24/S26A/S26B/S26C HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 Gene3D G3DSA:1.10.260.40 1 64 1.3E-21 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS05405 39d1b9638041faf4bd23b267f3deb4ae 229 Gene3D G3DSA:2.10.109.10 139 226 4.3E-17 T 21-04-2016 IPR028360 Peptidase S24/S26, beta-ribbon domain HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 PANTHER PTHR24220 7 245 7.0E-136 T 21-04-2016 HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 PIRSF PIRSF039085 2 245 9.0E-114 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 Gene3D G3DSA:3.40.50.300 6 241 2.5E-85 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 Pfam PF00005 ABC transporter 21 169 3.3E-35 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 SMART SM00382 30 217 3.6E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 SUPERFAMILY SSF52540 6 239 5.07E-81 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07210 fde523c3ce1dc6fbd8bf0579ffaea472 246 PANTHER PTHR24220:SF327 7 245 7.0E-136 T 21-04-2016 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 217 230 - T 21-04-2016 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 Reactome: REACT_13 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 SUPERFAMILY SSF53383 46 368 2.37E-80 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 Gene3D G3DSA:3.90.1150.10 259 368 3.3E-18 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 Gene3D G3DSA:3.40.640.10 49 258 5.1E-57 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 PANTHER PTHR11751 49 368 2.3E-91 T 21-04-2016 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 PANTHER PTHR11751:SF388 49 368 2.3E-91 T 21-04-2016 HSISS4_RS07165 f115cab690bec994c7638238d0d06278 369 Pfam PF00155 Aminotransferase class I and II 56 362 1.1E-44 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 42.827 T 21-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 127 223 1.1E-5 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 124 2.1E-28 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 229 5.2E-107 T 21-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 PANTHER PTHR11931 1 229 7.4E-140 T 21-04-2016 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484|UniPathway: UPA00109 HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 SUPERFAMILY SSF53254 1 228 2.36E-71 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 Gene3D G3DSA:3.40.50.1240 1 227 4.0E-91 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04115 04e2dc14c7d9c3c82d46fc87302eb055 230 SMART SM00855 3 189 1.2E-23 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS00310 e7a0e52d179575960e5d68f1457fb89e 145 SMART SM00850 49 145 2.3E-24 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS00310 e7a0e52d179575960e5d68f1457fb89e 145 Pfam PF04397 LytTr DNA-binding domain 50 144 6.9E-19 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS00310 e7a0e52d179575960e5d68f1457fb89e 145 Gene3D G3DSA:2.40.50.40 40 107 2.9E-10 T 21-04-2016 HSISS4_RS00310 e7a0e52d179575960e5d68f1457fb89e 145 PANTHER PTHR37299 1 145 2.8E-52 T 21-04-2016 HSISS4_RS00310 e7a0e52d179575960e5d68f1457fb89e 145 PANTHER PTHR37299:SF2 1 145 2.8E-52 T 21-04-2016 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 ProSitePatterns PS00770 Aminotransferases class-IV signature. 220 249 - T 21-04-2016 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 Gene3D G3DSA:3.30.470.10 3 160 1.8E-65 T 21-04-2016 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 SUPERFAMILY SSF56752 3 336 1.57E-99 T 21-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 Gene3D G3DSA:3.20.10.10 161 325 3.0E-54 T 21-04-2016 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 PANTHER PTHR11825 4 338 3.2E-157 T 21-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 30 339 1.2E-135 T 21-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 PIRSF PIRSF006468 2 340 6.1E-118 T 21-04-2016 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|Reactome: REACT_13 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 PANTHER PTHR11825:SF2 4 338 3.2E-157 T 21-04-2016 HSISS4_RS02775 35e0989f69223acd7c991799a536719b 340 Pfam PF01063 Amino-transferase class IV 56 293 2.4E-32 T 21-04-2016 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: REACT_13 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 Pfam PF00849 RNA pseudouridylate synthase 84 236 5.7E-31 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 PANTHER PTHR11079 33 294 3.1E-80 T 21-04-2016 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 127 141 - T 21-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 22 293 8.9E-69 T 21-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 PANTHER PTHR11079:SF73 33 294 3.1E-80 T 21-04-2016 HSISS4_RS07015 6ad705ea4231ab06b8e3554de64a3a5f 298 SUPERFAMILY SSF55120 69 290 6.24E-69 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 417 441 5.3E-36 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 392 414 5.3E-36 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 310 337 5.3E-36 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 PRINTS PR01852 Streptococcal non-M secreted SibA protein signature 462 485 5.3E-36 T 21-04-2016 IPR009148 Streptococcal non-M secreted SibA HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 Pfam PF05257 CHAP domain 389 469 1.9E-12 T 21-04-2016 IPR007921 CHAP domain HSISS4_RS00185 359846cfc71f6dc035bb909b0b2e098d 499 SUPERFAMILY SSF54001 387 488 3.63E-22 T 21-04-2016 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 Pfam PF00288 GHMP kinases N terminal domain 91 136 5.5E-8 T 21-04-2016 IPR006204 GHMP kinase N-terminal domain GO:0005524 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 PIRSF PIRSF015950 1 314 1.3E-97 T 21-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 SUPERFAMILY SSF54211 6 174 4.17E-34 T 21-04-2016 IPR020568 Ribosomal protein S5 domain 2-type fold HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 98 109 - T 21-04-2016 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 SUPERFAMILY SSF55060 169 301 6.04E-43 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 Gene3D G3DSA:3.30.70.890 169 300 6.5E-53 T 21-04-2016 IPR013750 GHMP kinase, C-terminal domain HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 PANTHER PTHR10977 6 301 2.1E-85 T 21-04-2016 IPR005935 Diphosphomevalonate/phosphomevalonate decarboxylase GO:0008299|GO:0016831 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 Gene3D G3DSA:3.30.230.10 4 168 4.7E-61 T 21-04-2016 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 TIGRFAM TIGR01240 mevDPdecarb: diphosphomevalonate decarboxylase 7 301 1.7E-122 T 21-04-2016 IPR029765 Diphosphomevalonate decarboxylase GO:0004163|GO:0005829|GO:0019287 KEGG: 00900+4.1.1.33|MetaCyc: PWY-7391|MetaCyc: PWY-922 HSISS4_RS02590 f2e3fc46907edb7c16f896181e8587d8 314 PANTHER PTHR10977:SF3 6 301 2.1E-85 T 21-04-2016 HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 SUPERFAMILY SSF51445 3 481 2.98E-164 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 Pfam PF02446 4-alpha-glucanotransferase 10 474 1.2E-156 T 21-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 PANTHER PTHR32438:SF5 2 496 4.8E-134 T 21-04-2016 HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 Gene3D G3DSA:3.20.20.80 2 496 8.6E-176 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 PANTHER PTHR32438 2 496 4.8E-134 T 21-04-2016 HSISS4_RS04835 f522d225ea3f81eb1a5c9de3904fb000 499 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 2 496 1.5E-103 T 21-04-2016 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 Pfam PF06176 Lipopolysaccharide core biosynthesis protein (WaaY) 212 282 1.6E-4 T 21-04-2016 IPR009330 Lipopolysaccharide core heptose(II) kinase KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.-|UniPathway: UPA00958 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 Gene3D G3DSA:3.30.200.20 182 224 9.9E-4 T 21-04-2016 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 Gene3D G3DSA:3.30.200.20 106 144 9.9E-4 T 21-04-2016 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 PANTHER PTHR10566 30 519 3.4E-126 T 21-04-2016 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 Pfam PF03109 ABC1 family 92 208 5.7E-31 T 21-04-2016 IPR004147 UbiB domain HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 Gene3D G3DSA:3.90.1200.10 237 286 3.5E-10 T 21-04-2016 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 PANTHER PTHR10566:SF10 30 519 3.4E-126 T 21-04-2016 HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 SUPERFAMILY SSF56112 74 137 7.72E-31 T 21-04-2016 IPR011009 Protein kinase-like domain HSISS4_RS04700 b017714d396667ef0a300c8ce1110202 525 SUPERFAMILY SSF56112 170 288 7.72E-31 T 21-04-2016 IPR011009 Protein kinase-like domain HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 72 2.7E-20 T 21-04-2016 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 PANTHER PTHR21197 1 361 4.9E-112 T 21-04-2016 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 Gene3D G3DSA:3.40.50.720 1 78 2.8E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 Gene3D G3DSA:3.40.50.720 181 254 2.8E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 Gene3D G3DSA:3.40.50.720 321 364 2.8E-44 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 1 362 3.6E-135 T 21-04-2016 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 SUPERFAMILY SSF51971 1 262 1.12E-51 T 21-04-2016 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 SUPERFAMILY SSF51971 331 361 1.12E-51 T 21-04-2016 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 SUPERFAMILY SSF54373 245 313 1.8E-26 T 21-04-2016 HSISS4_RS04645 55b95aeb54c58a4bb3cd6c2ca9bd7280 366 Pfam PF03275 UDP-galactopyranose mutase 146 346 3.3E-85 T 21-04-2016 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 SUPERFAMILY SSF55729 169 246 1.2E-30 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 Gene3D G3DSA:3.40.630.30 6 136 3.3E-8 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 SUPERFAMILY SSF55729 8 158 4.13E-21 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 PANTHER PTHR36174 1 398 1.2E-40 T 21-04-2016 HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 SUPERFAMILY SSF55729 306 401 1.2E-30 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 Gene3D G3DSA:3.40.630.30 304 390 8.1E-52 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 Gene3D G3DSA:3.40.630.30 137 246 8.1E-52 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01575 a1af2bf20b78696bbf03b0bed93744c9 410 Pfam PF02388 FemAB family 12 402 5.4E-69 T 21-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 SUPERFAMILY SSF81271 2 61 9.37E-17 T 21-04-2016 IPR012676 TGS-like KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 SUPERFAMILY SSF52954 533 637 2.11E-33 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 6.4E-16 T 21-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 641 34.661 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.30.980.10 187 222 2.2E-37 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.30.980.10 66 130 2.2E-37 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Pfam PF03129 Anticodon binding domain 547 636 1.1E-24 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 SUPERFAMILY SSF55681 242 532 5.18E-97 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.30.930.10 241 536 2.7E-107 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Pfam PF02824 TGS domain 2 61 2.0E-11 T 21-04-2016 IPR004095 TGS KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PANTHER PTHR11451 1 644 0.0 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 SMART SM00863 169 218 1.6E-23 T 21-04-2016 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.40.50.800 537 642 3.2E-36 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 SUPERFAMILY SSF55186 63 240 9.81E-65 T 21-04-2016 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 638 8.0E-230 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.10.20.30 1 64 3.4E-25 T 21-04-2016 IPR012675 Beta-grasp domain HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Gene3D G3DSA:3.30.54.20 131 186 1.3E-22 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PANTHER PTHR11451:SF5 1 644 0.0 T 21-04-2016 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 513 526 5.9E-46 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 331 359 5.9E-46 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 470 498 5.9E-46 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 364 387 5.9E-46 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 PRINTS PR01047 Threonyl-tRNA synthetase signature 540 552 5.9E-46 T 21-04-2016 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 HSISS4_RS02675 51c603aa69aef00c8e6c10f2a230e013 648 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 326 535 3.2E-34 T 21-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 PIRSF PIRSF001555 1 330 3.0E-155 T 21-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 Pfam PF03590 Aspartate-ammonia ligase 9 243 7.6E-95 T 21-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 Gene3D G3DSA:3.30.930.10 2 327 7.0E-156 T 21-04-2016 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 PANTHER PTHR30073 1 330 1.4E-195 T 21-04-2016 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 SUPERFAMILY SSF55681 5 330 1.72E-98 T 21-04-2016 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 Hamap MF_00555 Aspartate--ammonia ligase [asnA]. 1 330 46.603 T 21-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 PANTHER PTHR30073:SF5 1 330 1.4E-195 T 21-04-2016 HSISS4_RS01765 3bf33e980ba2c76eaf4bd459e6fedcf1 330 TIGRFAM TIGR00669 asnA: aspartate--ammonia ligase 1 330 1.1E-182 T 21-04-2016 IPR004618 Aspartate--ammonia ligase GO:0004071|GO:0005737|GO:0006529 KEGG: 00250+6.3.1.1|KEGG: 00460+6.3.1.1|UniPathway: UPA00134 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 TIGRFAM TIGR00077 lspA: signal peptidase II 5 143 9.3E-35 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 151 15.943 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 PANTHER PTHR33695:SF1 10 148 8.5E-42 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 48 56 2.7E-17 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 126 142 2.7E-17 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 107 2.7E-17 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 Pfam PF01252 Signal peptidase (SPase) II 10 144 3.4E-33 T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 ProSitePatterns PS00855 Signal peptidases II signature. 95 107 - T 21-04-2016 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 UniPathway: UPA00665 HSISS4_RS02440 79ab3e16b11ae2e9736962381f5152d0 153 PANTHER PTHR33695 10 148 8.5E-42 T 21-04-2016 HSISS4_RS02350 b6542d79265d5ec80ff7fc7f0b348b4a 169 Pfam PF10688 Bacterial inner membrane protein 5 164 8.8E-24 T 21-04-2016 IPR019629 Uncharacterised protein family HI1736/YgjV HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 SUPERFAMILY SSF50182 115 175 4.58E-14 T 21-04-2016 IPR010920 LSM domain HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 SUPERFAMILY SSF82689 179 270 1.7E-7 T 21-04-2016 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 Pfam PF00924 Mechanosensitive ion channel 72 268 3.4E-42 T 21-04-2016 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 PANTHER PTHR30460 1 271 2.1E-77 T 21-04-2016 HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 SUPERFAMILY SSF82861 25 113 3.53E-14 T 21-04-2016 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 HSISS4_RS00730 5dc60d759e914d664d4a594fc46cf1e1 280 Gene3D G3DSA:2.30.30.60 130 172 1.2E-13 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:3.40.50.300 195 377 8.4E-41 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 724 804 4.9E-25 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Pfam PF07724 AAA domain (Cdc48 subfamily) 546 717 5.3E-53 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SUPERFAMILY SSF81923 4 126 5.49E-11 T 21-04-2016 IPR004176 Clp, N-terminal GO:0019538 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SMART SM00382 547 687 1.4E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SMART SM00382 233 378 4.1E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 108 135 0.62 T 21-04-2016 IPR004176 Clp, N-terminal GO:0019538 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 15 46 0.014 T 21-04-2016 IPR004176 Clp, N-terminal GO:0019538 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:1.10.1780.10 3 139 6.7E-16 T 21-04-2016 IPR004176 Clp, N-terminal GO:0019538 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SUPERFAMILY SSF52540 196 454 8.2E-62 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:3.40.50.300 707 734 1.3E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:3.40.50.300 500 673 1.3E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PANTHER PTHR11638 4 145 0.0 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PANTHER PTHR11638 188 815 0.0 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 329 341 - T 21-04-2016 IPR018368 ClpA/B, conserved site 1 GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SUPERFAMILY SSF52540 496 799 3.63E-76 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 596 614 1.0E-41 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 658 672 1.0E-41 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 625 643 1.0E-41 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 551 569 1.0E-41 T 21-04-2016 IPR001270 ClpA/B family GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 SMART SM01086 724 813 1.1E-34 T 21-04-2016 IPR019489 Clp ATPase, C-terminal HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:1.10.8.60 735 814 5.2E-29 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 238 370 3.5E-12 T 21-04-2016 IPR003959 ATPase, AAA-type, core GO:0005524 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PANTHER PTHR11638:SF18 4 145 0.0 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 PANTHER PTHR11638:SF18 188 815 0.0 T 21-04-2016 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 581 599 - T 21-04-2016 IPR028299 ClpA/B, conserved site 2 HSISS4_RS00495 186b27b444258fc6caea7fa393b9f82e 816 Gene3D G3DSA:1.10.8.60 379 446 1.3E-24 T 21-04-2016 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PANTHER PTHR10285 2 205 2.6E-92 T 21-04-2016 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 150 161 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 35 46 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 172 185 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 5 22 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 136 146 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 PRINTS PR00988 Uridine kinase signature 80 95 1.82E-39 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.964 T 21-04-2016 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 8.5E-47 T 21-04-2016 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 SUPERFAMILY SSF52540 2 198 1.01E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 TIGRFAM TIGR00235 udk: uridine kinase 4 205 6.3E-88 T 21-04-2016 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|UniPathway: UPA00574|UniPathway: UPA00579 HSISS4_RS03740 fe7559b3b05c0415c1206a9e98505905 211 Gene3D G3DSA:3.40.50.300 4 206 1.0E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06175 50f8f8c7d510a491df91db0e6df15b84 138 SUPERFAMILY SSF50475 3 128 3.55E-13 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS06175 50f8f8c7d510a491df91db0e6df15b84 138 Gene3D G3DSA:2.30.110.10 1 138 1.1E-57 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS06175 50f8f8c7d510a491df91db0e6df15b84 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 84 3.4E-8 T 21-04-2016 IPR011576 Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain GO:0004733|GO:0010181|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|UniPathway: UPA00647 HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 PANTHER PTHR34386 4 73 1.4E-16 T 21-04-2016 HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 Pfam PF00462 Glutaredoxin 4 57 1.6E-13 T 21-04-2016 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 TIGRFAM TIGR02194 GlrX_NrdH: glutaredoxin-like protein NrdH 4 73 5.7E-35 T 21-04-2016 IPR011909 Glutaredoxin-like protein NrdH GO:0045454 HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 SUPERFAMILY SSF52833 3 74 6.1E-19 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 PANTHER PTHR34386:SF3 4 73 1.4E-16 T 21-04-2016 HSISS4_RS03685 7ae5e554b1d6cd58fe9431662b92b8b9 74 Gene3D G3DSA:3.40.30.10 2 74 1.1E-25 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 PANTHER PTHR30483 38 382 1.1E-83 T 21-04-2016 HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 PANTHER PTHR30483:SF6 38 382 1.1E-83 T 21-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 40 56 3.0E-5 T 21-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 78 3.0E-5 T 21-04-2016 IPR000709 Leu/Ile/Val-binding protein GO:0006865 HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 SUPERFAMILY SSF53822 38 381 1.31E-81 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 Pfam PF13458 Periplasmic binding protein 39 379 5.5E-53 T 21-04-2016 IPR028081 Leucine-binding protein domain HSISS4_RS01635 aa28d81e79ec86294c9d97580b03256e 391 Gene3D G3DSA:3.40.50.2300 38 239 1.0E-54 T 21-04-2016 HSISS4_RS07640 34b0befe0df72169bd97804bfbb4aaa2 390 Pfam PF07690 Major Facilitator Superfamily 34 322 3.7E-10 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS07640 34b0befe0df72169bd97804bfbb4aaa2 390 SUPERFAMILY SSF103473 8 384 9.94E-21 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS07640 34b0befe0df72169bd97804bfbb4aaa2 390 Gene3D G3DSA:1.20.1250.20 8 179 5.9E-5 T 21-04-2016 HSISS4_RS07640 34b0befe0df72169bd97804bfbb4aaa2 390 Gene3D G3DSA:1.20.1250.20 189 383 2.7E-8 T 21-04-2016 HSISS4_RS04360 4aa4ba9c5cba4da2163de30ae804e1b4 216 SUPERFAMILY SSF161098 13 197 4.45E-37 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04360 4aa4ba9c5cba4da2163de30ae804e1b4 216 PANTHER PTHR30614 9 216 1.6E-62 T 21-04-2016 HSISS4_RS04360 4aa4ba9c5cba4da2163de30ae804e1b4 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 102 1.5E-20 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS04360 4aa4ba9c5cba4da2163de30ae804e1b4 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 32 210 2.8E-19 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04360 4aa4ba9c5cba4da2163de30ae804e1b4 216 Gene3D G3DSA:1.10.3720.10 13 213 1.8E-41 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 PANTHER PTHR11468:SF3 30 800 0.0 T 21-04-2016 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 PIRSF PIRSF000460 2 801 4.5E-207 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 Pfam PF00343 Carbohydrate phosphorylase 97 798 2.5E-290 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 SUPERFAMILY SSF53756 5 800 3.53E-280 T 21-04-2016 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 Gene3D G3DSA:3.40.50.2000 6 469 7.3E-167 T 21-04-2016 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 Gene3D G3DSA:3.40.50.2000 470 783 2.2E-127 T 21-04-2016 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 8 799 0.0 T 21-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS06835 51da5d0efa6f1a6a1c03e2af39d43ed7 801 PANTHER PTHR11468 30 800 0.0 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 Gene3D G3DSA:1.10.357.10 2 195 2.6E-27 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 SUPERFAMILY SSF46689 2 72 7.98E-13 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 52 3.6E-8 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 PANTHER PTHR30328 1 193 1.9E-14 T 21-04-2016 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 PANTHER PTHR30328:SF6 1 193 1.9E-14 T 21-04-2016 HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 Pfam PF13305 WHG domain 87 169 5.4E-8 T 21-04-2016 IPR025996 WHG domain HSISS4_RS08780 7248b0463340b5216ee19db90f057f92 198 SUPERFAMILY SSF48498 80 195 8.67E-7 T 21-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HSISS4_RS07100 1f0baefd149442c4ae7ce826f92ed8c5 336 PANTHER PTHR22916 2 252 9.8E-36 T 21-04-2016 HSISS4_RS07100 1f0baefd149442c4ae7ce826f92ed8c5 336 Pfam PF00535 Glycosyl transferase family 2 6 127 5.0E-23 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS07100 1f0baefd149442c4ae7ce826f92ed8c5 336 SUPERFAMILY SSF53448 4 266 8.25E-39 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07100 1f0baefd149442c4ae7ce826f92ed8c5 336 PANTHER PTHR22916:SF24 2 252 9.8E-36 T 21-04-2016 HSISS4_RS07100 1f0baefd149442c4ae7ce826f92ed8c5 336 Gene3D G3DSA:3.90.550.10 4 199 3.4E-39 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 SUPERFAMILY SSF52833 103 195 3.74E-22 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Gene3D G3DSA:3.50.50.60 208 321 4.3E-23 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Gene3D G3DSA:3.40.30.10 102 195 4.6E-35 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Gene3D G3DSA:3.50.50.60 322 429 3.8E-30 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Gene3D G3DSA:3.40.30.10 2 93 3.3E-28 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 470 488 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 2.0E-63 T 21-04-2016 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Gene3D G3DSA:3.50.50.60 430 506 2.3E-13 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 SUPERFAMILY SSF52833 3 101 3.13E-27 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PANTHER PTHR22912 195 506 6.2E-166 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Pfam PF13192 Thioredoxin domain 124 194 3.9E-7 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PANTHER PTHR22912:SF107 195 506 6.2E-166 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 489 9.3E-45 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 21-04-2016 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 510 6.0E-224 T 21-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 SUPERFAMILY SSF51905 208 506 1.56E-46 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PIRSF PIRSF000238 2 510 3.1E-241 T 21-04-2016 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0016651|GO:0050660|GO:0051287|GO:0055114 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 7.0E-35 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 7.0E-35 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 460 482 7.0E-35 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 7.0E-35 T 21-04-2016 HSISS4_RS00465 7fa4ab1d0660404d808e657d674e8539 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 7.0E-35 T 21-04-2016 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 SUPERFAMILY SSF90123 5 335 4.32E-50 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 SMART SM00382 381 576 3.7E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 SUPERFAMILY SSF52540 349 594 6.85E-80 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 Pfam PF00005 ABC transporter 372 522 4.1E-31 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 Pfam PF00664 ABC transporter transmembrane region 18 271 4.3E-28 T 21-04-2016 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 Gene3D G3DSA:3.40.50.300 354 588 1.0E-70 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 Gene3D G3DSA:1.20.1560.10 4 335 1.1E-45 T 21-04-2016 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 PANTHER PTHR24221 1 277 1.3E-146 T 21-04-2016 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 PANTHER PTHR24221 294 603 1.3E-146 T 21-04-2016 HSISS4_RS01985 1e016bb21743c630cb80c29e606620b5 604 ProSitePatterns PS00211 ABC transporters family signature. 496 510 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08895 c077f768d4829389de94260ff01aaf30 263 PANTHER PTHR30520 6 258 4.0E-75 T 21-04-2016 HSISS4_RS08895 c077f768d4829389de94260ff01aaf30 263 PANTHER PTHR30520:SF5 6 258 4.0E-75 T 21-04-2016 HSISS4_RS08895 c077f768d4829389de94260ff01aaf30 263 Gene3D G3DSA:1.20.1080.10 22 257 1.5E-51 T 21-04-2016 IPR023271 Aquaporin-like HSISS4_RS08895 c077f768d4829389de94260ff01aaf30 263 Pfam PF01226 Formate/nitrite transporter 6 253 1.1E-45 T 21-04-2016 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 Gene3D G3DSA:3.30.1310.10 1 97 5.4E-29 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 Pfam PF02575 YbaB/EbfC DNA-binding family 8 97 4.0E-27 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 PANTHER PTHR33449 1 99 2.2E-32 T 21-04-2016 HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 SUPERFAMILY SSF82607 4 95 4.05E-26 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 PANTHER PTHR33449:SF1 1 99 2.2E-32 T 21-04-2016 HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 2 96 19.829 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 PIRSF PIRSF004555 1 99 4.6E-27 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS07700 1f18e7231a41cbcef18a58d82e8fa10c 99 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 91 7.8E-22 T 21-04-2016 IPR004401 Nucleoid-associated protein YbaB/EbfC family HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 322 339 - T 21-04-2016 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PANTHER PTHR11071:SF282 213 388 3.2E-88 T 21-04-2016 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PANTHER PTHR11071:SF282 413 466 3.2E-88 T 21-04-2016 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 301 316 2.3E-16 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 369 384 2.3E-16 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 327 339 2.3E-16 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 SUPERFAMILY SSF56784 8 267 1.68E-61 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PANTHER PTHR11071 213 388 3.2E-88 T 21-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 PANTHER PTHR11071 413 466 3.2E-88 T 21-04-2016 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 SUPERFAMILY SSF50891 415 466 4.82E-55 T 21-04-2016 IPR029000 Cyclophilin-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 SUPERFAMILY SSF50891 280 387 4.82E-55 T 21-04-2016 IPR029000 Cyclophilin-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 16 263 2.7E-52 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 288 466 5.1E-47 T 21-04-2016 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 Gene3D G3DSA:2.40.100.10 282 467 1.5E-64 T 21-04-2016 IPR029000 Cyclophilin-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 Pfam PF08282 haloacid dehalogenase-like hydrolase 17 263 1.4E-47 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 Gene3D G3DSA:3.40.50.1000 7 84 1.6E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 Gene3D G3DSA:3.40.50.1000 172 270 1.6E-50 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS02950 01b0a3e15cca6eff8e4bf1440be2fb41 468 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 16 236 8.3E-19 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS07235 57af2554eed168d5a630b8336d4ffe4d 127 Pfam PF03061 Thioesterase superfamily 38 110 5.3E-15 T 21-04-2016 IPR006683 Thioesterase domain HSISS4_RS07235 57af2554eed168d5a630b8336d4ffe4d 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 20 120 1.9E-17 T 21-04-2016 IPR003736 Phenylacetic acid degradation-related domain HSISS4_RS07235 57af2554eed168d5a630b8336d4ffe4d 127 SUPERFAMILY SSF54637 18 122 4.05E-25 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS07235 57af2554eed168d5a630b8336d4ffe4d 127 PANTHER PTHR21660 8 121 4.7E-18 T 21-04-2016 HSISS4_RS07235 57af2554eed168d5a630b8336d4ffe4d 127 Gene3D G3DSA:3.10.129.10 14 123 6.7E-33 T 21-04-2016 IPR029069 HotDog domain HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 PANTHER PTHR30346 1 298 3.8E-73 T 21-04-2016 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 SUPERFAMILY SSF53850 92 296 3.8E-20 T 21-04-2016 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 SUPERFAMILY SSF46785 1 82 5.88E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.4E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.4E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.4E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.0E-17 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 PANTHER PTHR30346:SF0 1 298 3.8E-73 T 21-04-2016 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 Gene3D G3DSA:1.10.10.10 1 80 3.9E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 Gene3D G3DSA:3.40.190.10 112 184 7.4E-6 T 21-04-2016 HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 Pfam PF03466 LysR substrate binding domain 119 295 7.1E-9 T 21-04-2016 IPR005119 LysR, substrate-binding HSISS4_RS05490 b6ac814b0bc2c5995a0d9183617c247a 302 Gene3D G3DSA:3.40.190.10 185 266 4.4E-6 T 21-04-2016 HSISS4_RS07250 a3d87819514c3cde94b2fc43b809c99a 296 PANTHER PTHR12715 1 295 5.8E-47 T 21-04-2016 HSISS4_RS07250 a3d87819514c3cde94b2fc43b809c99a 296 Pfam PF00892 EamA-like transporter family 7 140 2.5E-19 T 21-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HSISS4_RS07250 a3d87819514c3cde94b2fc43b809c99a 296 Pfam PF00892 EamA-like transporter family 152 293 3.2E-10 T 21-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HSISS4_RS07250 a3d87819514c3cde94b2fc43b809c99a 296 SUPERFAMILY SSF103481 212 294 4.32E-11 T 21-04-2016 HSISS4_RS07250 a3d87819514c3cde94b2fc43b809c99a 296 SUPERFAMILY SSF103481 41 142 3.92E-13 T 21-04-2016 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 Pfam PF03315 Serine dehydratase beta chain 8 81 1.5E-11 T 21-04-2016 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 Gene3D G3DSA:3.30.70.260 139 220 9.8E-24 T 21-04-2016 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 5 205 9.6E-66 T 21-04-2016 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 PANTHER PTHR30182 1 222 1.6E-109 T 21-04-2016 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 Pfam PF01842 ACT domain 153 214 3.2E-8 T 21-04-2016 IPR002912 ACT domain GO:0008152|GO:0016597 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 SUPERFAMILY SSF143548 22 141 8.24E-29 T 21-04-2016 IPR029009 Allosteric substrate binding domain HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 PIRSF PIRSF036692 4 223 2.2E-103 T 21-04-2016 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 PANTHER PTHR30182:SF2 1 222 1.6E-109 T 21-04-2016 HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 Gene3D G3DSA:3.30.1330.90 16 138 1.3E-29 T 21-04-2016 IPR029009 Allosteric substrate binding domain HSISS4_RS05995 881354591b0a713cfb6ed60325dbbc7d 223 SUPERFAMILY SSF55021 140 220 1.54E-18 T 21-04-2016 HSISS4_RS04450 691f2e7ac8896388ef90e0c3ecfae700 309 PANTHER PTHR30489 84 308 2.6E-29 T 21-04-2016 HSISS4_RS04450 691f2e7ac8896388ef90e0c3ecfae700 309 PANTHER PTHR30489 18 68 2.6E-29 T 21-04-2016 HSISS4_RS04450 691f2e7ac8896388ef90e0c3ecfae700 309 PIRSF PIRSF003097 1 309 1.1E-74 T 21-04-2016 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 HSISS4_RS04450 691f2e7ac8896388ef90e0c3ecfae700 309 Pfam PF02687 FtsX-like permease family 187 304 3.0E-12 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 PANTHER PTHR30521:SF4 45 401 4.1E-167 T 21-04-2016 HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 9 401 6.8E-147 T 21-04-2016 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 KEGG: 00480+1.11.1.- HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 PANTHER PTHR30521 45 401 4.1E-167 T 21-04-2016 HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 12 36 3.2E-5 T 21-04-2016 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 SUPERFAMILY SSF54909 57 395 6.61E-86 T 21-04-2016 IPR011008 Dimeric alpha-beta barrel HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 62 390 5.3E-95 T 21-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- HSISS4_RS04790 5cc42da4d671e064c7dd0adf364b8af2 401 Pfam PF04261 Dyp-type peroxidase family 62 390 7.4E-105 T 21-04-2016 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 KEGG: 00480+1.11.1.- HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 PIRSF PIRSF002181 1 147 1.9E-46 T 21-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 SUPERFAMILY SSF52161 6 144 5.1E-56 T 21-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 144 7.0E-58 T 21-04-2016 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 ProSitePatterns PS00783 Ribosomal protein L13 signature. 107 129 - T 21-04-2016 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 Gene3D G3DSA:3.90.1180.10 5 143 1.2E-60 T 21-04-2016 IPR023564 Ribosomal protein L13 domain GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 Pfam PF00572 Ribosomal protein L13 16 140 9.3E-53 T 21-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 PANTHER PTHR11545 4 144 1.8E-68 T 21-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS00565 44ac0872a8d402d800b85bb62cec4abe 148 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 17 143 25.863 T 21-04-2016 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS03870 ead61da99a97245b68e66cc8e0acb17d 307 PANTHER PTHR40446 116 305 7.5E-18 T 21-04-2016 HSISS4_RS03870 ead61da99a97245b68e66cc8e0acb17d 307 Pfam PF09992 Phosphodiester glycosidase 122 305 3.2E-41 T 21-04-2016 IPR018711 Phosphodiester glycosidase HSISS4_RS03870 ead61da99a97245b68e66cc8e0acb17d 307 PANTHER PTHR40446:SF1 116 305 7.5E-18 T 21-04-2016 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 21-04-2016 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 PANTHER PTHR32119 1 229 8.8E-113 T 21-04-2016 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 SMART SM00934 5 224 2.1E-98 T 21-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 3 229 41.215 T 21-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 SUPERFAMILY SSF51366 2 229 3.6E-74 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 Gene3D G3DSA:3.20.20.70 2 228 2.4E-86 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 225 3.0E-64 T 21-04-2016 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 PANTHER PTHR32119:SF2 1 229 8.8E-113 T 21-04-2016 HSISS4_RS05005 acd7b919388332f4561cbd13768b5a03 231 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 7 223 2.7E-54 T 21-04-2016 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|UniPathway: UPA00070 HSISS4_RS07555 4484a7150ffc9a7f93319cef23ac2d3b 191 PANTHER PTHR41316 1 187 4.3E-39 T 21-04-2016 HSISS4_RS07555 4484a7150ffc9a7f93319cef23ac2d3b 191 TIGRFAM TIGR02357 ECF_ThiT_YuaJ: energy-coupled thiamine transporter ThiT 7 186 5.2E-63 T 21-04-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 HSISS4_RS07555 4484a7150ffc9a7f93319cef23ac2d3b 191 Pfam PF09515 Thiamine transporter protein (Thia_YuaJ) 9 186 9.4E-62 T 21-04-2016 IPR012651 Thiamine transporter ThiT GO:0005886|GO:0015234|GO:0015888 HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 SUPERFAMILY SSF88697 1 66 2.41E-19 T 21-04-2016 IPR015947 PUA-like domain HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 PANTHER PTHR11061 1 384 2.9E-112 T 21-04-2016 HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 Gene3D G3DSA:3.40.50.150 111 385 6.1E-67 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 PANTHER PTHR11061:SF15 1 384 2.9E-112 T 21-04-2016 HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 161 366 3.2E-30 T 21-04-2016 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 HSISS4_RS03000 1dc167f26d91e08b6793332b764748ea 387 SUPERFAMILY SSF53335 75 382 1.77E-62 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS06050 8dfd0fd5e5828f370d41b848858d56ca 153 SUPERFAMILY SSF55729 28 152 1.86E-19 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS06050 8dfd0fd5e5828f370d41b848858d56ca 153 Pfam PF13508 Acetyltransferase (GNAT) domain 45 131 1.1E-11 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS06050 8dfd0fd5e5828f370d41b848858d56ca 153 Gene3D G3DSA:3.40.630.30 2 152 6.5E-22 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01585 4fa36de911161bc6c9f509e1886f4e3a 543 PANTHER PTHR30250:SF6 3 540 3.2E-143 T 21-04-2016 HSISS4_RS01585 4fa36de911161bc6c9f509e1886f4e3a 543 PANTHER PTHR30250 3 540 3.2E-143 T 21-04-2016 HSISS4_RS01585 4fa36de911161bc6c9f509e1886f4e3a 543 Pfam PF01943 Polysaccharide biosynthesis protein 14 323 4.0E-32 T 21-04-2016 IPR002797 Polysaccharide biosynthesis protein GO:0016020 HSISS4_RS01585 4fa36de911161bc6c9f509e1886f4e3a 543 PIRSF PIRSF038958 8 539 2.5E-69 T 21-04-2016 IPR024923 Peptidoglycan biosynthesis protein, SpoVB type HSISS4_RS01585 4fa36de911161bc6c9f509e1886f4e3a 543 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 378 523 7.3E-25 T 21-04-2016 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 PANTHER PTHR24220 3 247 1.8E-113 T 21-04-2016 HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 Gene3D G3DSA:3.40.50.300 1 239 8.1E-83 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 SUPERFAMILY SSF52540 1 238 1.09E-75 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 PANTHER PTHR24220:SF550 3 247 1.8E-113 T 21-04-2016 HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 Pfam PF00005 ABC transporter 17 168 2.9E-35 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 ProSitePatterns PS01095 Chitinases family 18 active site. 17 25 - T 21-04-2016 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6902 HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 SMART SM00382 26 216 3.9E-18 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08000 daca83a5b19ef2a8f01cff0553e7ce34 247 PIRSF PIRSF039085 1 244 4.7E-97 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS03185 9d357e197b121df2e1c1ac8c3c107515 347 Pfam PF01032 FecCD transport family 24 341 2.4E-84 T 21-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HSISS4_RS03185 9d357e197b121df2e1c1ac8c3c107515 347 PANTHER PTHR30472 12 347 4.1E-105 T 21-04-2016 IPR000522 ABC transporter, permease protein GO:0005215|GO:0016020 HSISS4_RS03185 9d357e197b121df2e1c1ac8c3c107515 347 Gene3D G3DSA:1.10.3470.10 13 345 2.2E-96 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS03185 9d357e197b121df2e1c1ac8c3c107515 347 PANTHER PTHR30472:SF32 12 347 4.1E-105 T 21-04-2016 HSISS4_RS03185 9d357e197b121df2e1c1ac8c3c107515 347 SUPERFAMILY SSF81345 9 341 5.89E-75 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS03595 bdcca0e912b6db37955a69f802f96a19 145 PANTHER PTHR33202:SF7 12 145 3.1E-38 T 21-04-2016 HSISS4_RS03595 bdcca0e912b6db37955a69f802f96a19 145 PANTHER PTHR33202 12 145 3.1E-38 T 21-04-2016 HSISS4_RS03595 bdcca0e912b6db37955a69f802f96a19 145 Gene3D G3DSA:1.10.10.10 12 89 2.3E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS03595 bdcca0e912b6db37955a69f802f96a19 145 Pfam PF01475 Ferric uptake regulator family 21 137 1.0E-30 T 21-04-2016 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 HSISS4_RS03595 bdcca0e912b6db37955a69f802f96a19 145 SUPERFAMILY SSF46785 12 143 1.15E-34 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS00605 f8189073bdda6c0f462624322b92c4ef 216 PANTHER PTHR13887:SF10 1 213 4.8E-36 T 21-04-2016 HSISS4_RS00605 f8189073bdda6c0f462624322b92c4ef 216 SUPERFAMILY SSF52833 1 212 5.6E-37 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00605 f8189073bdda6c0f462624322b92c4ef 216 Gene3D G3DSA:3.40.30.10 1 209 1.3E-37 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS00605 f8189073bdda6c0f462624322b92c4ef 216 Pfam PF01323 DSBA-like thioredoxin domain 3 203 2.0E-31 T 21-04-2016 IPR001853 DSBA-like thioredoxin domain GO:0015035 HSISS4_RS00605 f8189073bdda6c0f462624322b92c4ef 216 PANTHER PTHR13887 1 213 4.8E-36 T 21-04-2016 HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 21 171 1.9E-60 T 21-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 Gene3D G3DSA:3.80.30.10 83 195 6.2E-16 T 21-04-2016 HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 PIRSF PIRSF000368 11 185 1.7E-71 T 21-04-2016 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 KEGG: 00351+1.97.1.-|KEGG: 00361+1.97.1.-|KEGG: 00363+1.97.1.-|KEGG: 00625+1.97.1.- HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 Pfam PF13353 4Fe-4S single cluster domain 30 168 7.2E-53 T 21-04-2016 HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 PANTHER PTHR30352:SF2 1 201 2.7E-103 T 21-04-2016 HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 PANTHER PTHR30352 1 201 2.7E-103 T 21-04-2016 HSISS4_RS09440 f1a84cd9d10170a8a622afd95f39a400 201 SUPERFAMILY SSF102114 42 116 1.16E-9 T 21-04-2016 HSISS4_RS03270 2ad7c73fde3e901225856e0d91ddf87d 120 TIGRFAM TIGR02328 TIGR02328: conserved hypothetical protein 1 120 7.7E-60 T 21-04-2016 IPR012650 Conserved hypothetical protein CHP02328 HSISS4_RS03270 2ad7c73fde3e901225856e0d91ddf87d 120 Pfam PF03013 Pyrimidine dimer DNA glycosylase 1 109 1.1E-33 T 21-04-2016 IPR004260 Pyrimidine dimer DNA glycosylase HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 PIRSF PIRSF006603 8 449 4.5E-65 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 PANTHER PTHR11206:SF153 3 449 2.0E-168 T 21-04-2016 HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 Pfam PF01554 MatE 246 407 1.8E-29 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 Pfam PF01554 MatE 20 180 1.2E-27 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 PANTHER PTHR11206 3 449 2.0E-168 T 21-04-2016 HSISS4_RS06180 07663698d3cce8197360c7312fbbbcc1 449 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 420 2.4E-78 T 21-04-2016 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: REACT_15518|Reactome: REACT_20633 HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 250 9.2E-46 T 21-04-2016 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 SUPERFAMILY SSF56300 1 331 7.12E-52 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 Pfam PF00149 Calcineurin-like phosphoesterase 1 225 6.1E-15 T 21-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 Gene3D G3DSA:3.60.21.10 1 276 1.4E-62 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 PANTHER PTHR30337 1 263 1.2E-58 T 21-04-2016 HSISS4_RS06775 fec28b1dea10fca5221a0472b5c98115 402 PANTHER PTHR30337:SF0 1 263 1.2E-58 T 21-04-2016 HSISS4_RS00545 9a38af2247233fc9d1587ffa82b73bff 171 Pfam PF05991 YacP-like NYN domain 6 166 2.2E-49 T 21-04-2016 IPR010298 Protein of unknown function DUF901 HSISS4_RS00545 9a38af2247233fc9d1587ffa82b73bff 171 PANTHER PTHR34547 5 141 2.2E-41 T 21-04-2016 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 199 33.419 T 21-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 PIRSF PIRSF000495 1 202 1.8E-67 T 21-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 SUPERFAMILY SSF52317 2 199 1.04E-52 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 197 8.7E-63 T 21-04-2016 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 UniPathway: UPA00031 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 PANTHER PTHR21235 2 197 1.2E-80 T 21-04-2016 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 Gene3D G3DSA:3.40.50.880 1 202 5.3E-72 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 PANTHER PTHR21235:SF1 2 197 1.2E-80 T 21-04-2016 HSISS4_RS03905 453d7f42cdaf8bae79c5f5806306089e 202 Pfam PF00117 Glutamine amidotransferase class-I 4 186 1.8E-23 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS05180 6684c70f3a0b0f194587df5c483bc7de 360 PANTHER PTHR30294:SF12 1 359 1.4E-66 T 21-04-2016 HSISS4_RS05180 6684c70f3a0b0f194587df5c483bc7de 360 PANTHER PTHR30294 1 359 1.4E-66 T 21-04-2016 HSISS4_RS05180 6684c70f3a0b0f194587df5c483bc7de 360 Pfam PF12698 ABC-2 family transporter protein 18 351 1.5E-44 T 21-04-2016 HSISS4_RS00915 30dfa27095aca427efa2dab7754e274f 312 Pfam PF03547 Membrane transport protein 11 156 8.9E-19 T 21-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HSISS4_RS00915 30dfa27095aca427efa2dab7754e274f 312 Pfam PF03547 Membrane transport protein 163 307 2.1E-20 T 21-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HSISS4_RS00915 30dfa27095aca427efa2dab7754e274f 312 PANTHER PTHR31752 91 312 1.6E-39 T 21-04-2016 HSISS4_RS00915 30dfa27095aca427efa2dab7754e274f 312 PANTHER PTHR31752:SF7 91 312 1.6E-39 T 21-04-2016 HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 Gene3D G3DSA:2.40.320.10 4 171 3.6E-15 T 21-04-2016 IPR023577 CYTH domain HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 Pfam PF01928 CYTH domain 4 182 5.9E-31 T 21-04-2016 IPR023577 CYTH domain HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 SMART SM01118 3 189 2.0E-18 T 21-04-2016 IPR023577 CYTH domain HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 PANTHER PTHR41266 1 191 1.8E-56 T 21-04-2016 HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 PIRSF PIRSF012526 1 190 2.6E-70 T 21-04-2016 IPR009195 Uncharacterised protein family YjbK KEGG: 00230+3.6.1.-|KEGG: 00332+3.6.1.-|KEGG: 00790+3.6.1.- HSISS4_RS07030 f3102a3d46648130f16a4e75fb22461f 191 SUPERFAMILY SSF55154 2 185 1.23E-30 T 21-04-2016 IPR033469 CYTH-like domain HSISS4_RS06750 d6e53c725ebd4d0f699d493162523ada 512 Gene3D G3DSA:3.40.50.1820 331 381 1.4E-4 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS06750 d6e53c725ebd4d0f699d493162523ada 512 Pfam PF16929 Accessory Sec system GspB-transporter 8 510 3.7E-182 T 21-04-2016 IPR022267 Accessory Sec system protein Asp2 GO:0015031 HSISS4_RS06750 d6e53c725ebd4d0f699d493162523ada 512 TIGRFAM TIGR03712 acc_sec_asp2: accessory Sec system protein Asp2 8 511 1.6E-198 T 21-04-2016 IPR022267 Accessory Sec system protein Asp2 GO:0015031 HSISS4_RS06750 d6e53c725ebd4d0f699d493162523ada 512 SUPERFAMILY SSF53474 341 405 1.2E-5 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 PANTHER PTHR11075:SF6 1 326 5.4E-148 T 21-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 SMART SM00937 35 153 3.8E-54 T 21-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 203 219 - T 21-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 Pfam PF00472 RF-1 domain 187 296 1.9E-38 T 21-04-2016 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 323 4.6E-142 T 21-04-2016 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 Pfam PF03462 PCRF domain 1 178 1.7E-57 T 21-04-2016 IPR005139 Peptide chain release factor GO:0005737|GO:0006415|GO:0016149 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 PANTHER PTHR11075 1 326 5.4E-148 T 21-04-2016 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 Gene3D G3DSA:1.20.58.410 1 73 1.2E-13 T 21-04-2016 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 SUPERFAMILY SSF75620 1 325 3.79E-128 T 21-04-2016 HSISS4_RS04440 d652672121beb9e4d010e14c9be7ca4a 326 Gene3D G3DSA:3.30.160.20 186 264 2.0E-32 T 21-04-2016 IPR014720 Double-stranded RNA-binding domain HSISS4_RS09060 faf0c3702cc69d09bdc7b1cca725c8b4 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 11 30 6.0E-4 T 21-04-2016 IPR012902 Prokaryotic N-terminal methylation site HSISS4_RS04605 30d81857bcc37b93c43ed940f92d2450 455 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 17 455 6.5E-119 T 21-04-2016 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase HSISS4_RS04605 30d81857bcc37b93c43ed940f92d2450 455 Pfam PF02397 Bacterial sugar transferase 262 449 3.2E-56 T 21-04-2016 IPR003362 Bacterial sugar transferase HSISS4_RS04605 30d81857bcc37b93c43ed940f92d2450 455 PANTHER PTHR30576 7 454 4.1E-107 T 21-04-2016 HSISS4_RS04605 30d81857bcc37b93c43ed940f92d2450 455 Pfam PF13727 CoA-binding domain 56 206 6.8E-8 T 21-04-2016 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 PANTHER PTHR22911 6 294 1.1E-95 T 21-04-2016 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 SUPERFAMILY SSF103481 39 148 1.05E-10 T 21-04-2016 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 Pfam PF00892 EamA-like transporter family 7 146 8.3E-16 T 21-04-2016 IPR000620 EamA domain GO:0016020|GO:0016021 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 SUPERFAMILY SSF103481 191 285 3.92E-10 T 21-04-2016 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 TIGRFAM TIGR00688 rarD: protein RarD 6 259 3.6E-62 T 21-04-2016 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 HSISS4_RS02200 e703d8226c58c273fcbb4fe9ddf074df 294 PANTHER PTHR22911:SF41 6 294 1.1E-95 T 21-04-2016 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 179 208 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 107 136 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 224 252 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 141 170 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 261 290 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PRINTS PR00142 RecA protein signature 315 332 6.5E-81 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 SUPERFAMILY SSF54752 286 344 1.07E-19 T 21-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 SUPERFAMILY SSF52540 18 285 2.88E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 Pfam PF00154 recA bacterial DNA recombination protein 21 286 4.4E-139 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 Gene3D G3DSA:3.30.250.10 286 344 7.0E-26 T 21-04-2016 IPR023400 DNA recombination and repair protein RecA, C-terminal HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 Hamap MF_00268 Protein RecA [recA]. 19 347 50.664 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PANTHER PTHR22942:SF1 17 353 1.3E-192 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 PANTHER PTHR22942 17 353 1.3E-192 T 21-04-2016 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 ProSitePatterns PS00321 recA signature. 227 235 - T 21-04-2016 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 18 341 2.7E-160 T 21-04-2016 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 Gene3D G3DSA:3.40.50.300 40 285 4.2E-74 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00345 22164b3f291aa8d8ce6215874fb3ac78 379 SMART SM00382 71 242 1.2E-7 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Pfam PF00122 E1-E2 ATPase 69 289 9.7E-46 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Gene3D G3DSA:3.40.50.1000 430 579 1.8E-36 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF56784 393 609 8.93E-40 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF56784 296 316 8.93E-40 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 300 306 - T 21-04-2016 IPR018303 P-type ATPase, phosphorylation site HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Gene3D G3DSA:3.40.1110.10 289 376 3.2E-8 T 21-04-2016 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 336 2.2E-31 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 500 615 6.1E-23 T 21-04-2016 IPR001757 P-type ATPase GO:0016021 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF81653 101 193 4.45E-21 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 467 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 298 312 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 435 446 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 552 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 568 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 147 161 4.5E-20 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PANTHER PTHR24093:SF298 9 782 9.0E-248 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Pfam PF00702 haloacid dehalogenase-like hydrolase 294 547 2.2E-29 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF81665 198 292 1.96E-41 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF81665 582 772 1.96E-41 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 SUPERFAMILY SSF81665 9 101 1.96E-41 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PANTHER PTHR24093 9 782 9.0E-248 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Gene3D G3DSA:2.70.150.10 92 194 2.1E-28 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 Gene3D G3DSA:2.70.150.10 8 44 2.1E-28 T 21-04-2016 IPR008250 P-type ATPase, A domain GO:0000166|GO:0046872 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 706 727 6.3E-6 T 21-04-2016 HSISS4_RS07685 2bfad34498cc1e48328c41b82723add0 782 PRINTS PR00121 Sodium/potassium-transporting ATPase signature 291 312 6.3E-6 T 21-04-2016 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PRINTS PR00139 Asparaginase/glutaminase family signature 5 16 1.1E-18 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 1.1E-18 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 1.1E-18 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PANTHER PTHR11707 5 321 8.0E-58 T 21-04-2016 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PIRSF PIRSF500176 1 322 9.5E-96 T 21-04-2016 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 SUPERFAMILY SSF53774 2 321 1.7E-93 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 21-04-2016 IPR027475 Asparaginase/glutaminase, active site 2 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 Pfam PF00710 Asparaginase, N-terminal 4 186 1.6E-55 T 21-04-2016 IPR027474 L-asparaginase, N-terminal HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 Gene3D G3DSA:3.40.50.40 204 321 9.4E-29 T 21-04-2016 IPR027473 L-asparaginase, C-terminal domain HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 PIRSF PIRSF001220 1 321 1.8E-91 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 7 15 - T 21-04-2016 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 SMART SM00870 4 317 3.0E-132 T 21-04-2016 IPR006034 Asparaginase/glutaminase GO:0006520 HSISS4_RS08285 d59b0c75653096098111b65b38b9df05 322 Gene3D G3DSA:3.40.50.1170 2 202 2.8E-60 T 21-04-2016 IPR027474 L-asparaginase, N-terminal HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 3.5E-32 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 Gene3D G3DSA:3.30.1340.10 1 83 3.0E-33 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 PRINTS PR00107 Phosphocarrier protein signature 13 29 7.4E-27 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 PRINTS PR00107 Phosphocarrier protein signature 53 70 7.4E-27 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 PRINTS PR00107 Phosphocarrier protein signature 38 53 7.4E-27 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 PANTHER PTHR33705 1 84 1.1E-35 T 21-04-2016 HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 21-04-2016 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 PANTHER PTHR33705:SF2 1 84 1.1E-35 T 21-04-2016 HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 21-04-2016 IPR002114 Phosphotransferase system, HPr serine phosphorylation site HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 Pfam PF00381 PTS HPr component phosphorylation site 3 81 4.0E-29 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS03705 08a75dadb5488b52fafa7d1801b315a5 87 SUPERFAMILY SSF55594 1 83 4.58E-28 T 21-04-2016 IPR000032 Phosphocarrier HPr protein-like HSISS4_RS08855 99de1fda048839e8acd1d42bfd664db7 117 Pfam PF11877 Protein of unknown function (DUF3397) 6 114 2.2E-25 T 21-04-2016 IPR024515 Protein of unknown function DUF3397 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 PRINTS PR00297 10kDa chaperonin signature 81 94 7.6E-17 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 PRINTS PR00297 10kDa chaperonin signature 25 46 7.6E-17 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 PRINTS PR00297 10kDa chaperonin signature 60 72 7.6E-17 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 PRINTS PR00297 10kDa chaperonin signature 3 18 7.6E-17 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 18.156 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 PANTHER PTHR10772 1 94 7.1E-24 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 21-04-2016 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 SMART SM00883 2 94 3.6E-34 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 Gene3D G3DSA:2.30.33.40 2 94 5.6E-26 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 Pfam PF00166 Chaperonin 10 Kd subunit 3 93 1.3E-21 T 21-04-2016 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 HSISS4_RS00985 b4952aee6d64e94144d5cc423cded070 95 SUPERFAMILY SSF50129 1 94 5.77E-24 T 21-04-2016 IPR011032 GroES-like HSISS4_RS00640 a873151c77fe10bf6a2c22d686ac180f 88 SUPERFAMILY SSF55021 1 81 1.26E-20 T 21-04-2016 HSISS4_RS00640 a873151c77fe10bf6a2c22d686ac180f 88 Gene3D G3DSA:3.30.70.260 1 87 6.3E-31 T 21-04-2016 HSISS4_RS00640 a873151c77fe10bf6a2c22d686ac180f 88 Hamap MF_01054 UPF0237 protein . 1 88 24.683 T 21-04-2016 IPR022986 Uncharacterised protein family UPF0237, ACT-type HSISS4_RS00640 a873151c77fe10bf6a2c22d686ac180f 88 PANTHER PTHR34875 1 88 6.8E-29 T 21-04-2016 HSISS4_RS00640 a873151c77fe10bf6a2c22d686ac180f 88 Pfam PF13740 ACT domain 4 75 9.4E-13 T 21-04-2016 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 SUPERFAMILY SSF46785 11 142 3.29E-28 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 PANTHER PTHR33164 31 143 4.4E-18 T 21-04-2016 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 Pfam PF01047 MarR family 34 91 5.7E-12 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 SMART SM00347 26 126 6.1E-19 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 Gene3D G3DSA:1.10.10.10 7 142 1.4E-34 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS01785 a04ea4e8e6a5d1af25e672927dccf7e5 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 1.1E-10 T 21-04-2016 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 PANTHER PTHR24220:SF534 6 238 3.3E-93 T 21-04-2016 HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 SUPERFAMILY SSF52540 4 238 2.39E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 Pfam PF00005 ABC transporter 25 180 1.3E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 Gene3D G3DSA:3.40.50.300 2 238 7.0E-59 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 PANTHER PTHR24220 6 238 3.3E-93 T 21-04-2016 HSISS4_RS04180 7270b297230829076372d9d66f111d03 252 SMART SM00382 34 229 1.7E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 Gene3D G3DSA:3.40.50.300 3 217 2.4E-63 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 SMART SM00382 32 215 6.9E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 PANTHER PTHR24220 5 217 4.2E-98 T 21-04-2016 HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 SUPERFAMILY SSF52540 4 219 5.44E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 Pfam PF00005 ABC transporter 24 166 2.1E-34 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS05245 62c205423188f21b97506fe5c0c97264 233 PANTHER PTHR24220:SF577 5 217 4.2E-98 T 21-04-2016 HSISS4_RS03210 6a526214d4d83330837eb4d4f4449d5b 341 PANTHER PTHR20992 9 338 1.8E-62 T 21-04-2016 HSISS4_RS03210 6a526214d4d83330837eb4d4f4449d5b 341 Pfam PF04087 Domain of unknown function (DUF389) 57 193 9.5E-37 T 21-04-2016 IPR005240 Protein of unknown function DUF389 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 PANTHER PTHR30308:SF2 1 154 1.4E-76 T 21-04-2016 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 Pfam PF01668 SmpB protein 8 72 2.8E-31 T 21-04-2016 IPR000037 SsrA-binding protein GO:0003723 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 21-04-2016 IPR020081 SsrA-binding protein, conserved site HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 Gene3D G3DSA:2.40.280.10 8 127 1.9E-51 T 21-04-2016 IPR023620 Small protein B HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 4.4E-57 T 21-04-2016 IPR000037 SsrA-binding protein GO:0003723 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 PANTHER PTHR30308 1 154 1.4E-76 T 21-04-2016 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 SUPERFAMILY SSF74982 4 132 1.31E-50 T 21-04-2016 IPR023620 Small protein B HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 71.676 T 21-04-2016 IPR000037 SsrA-binding protein GO:0003723 HSISS4_RS02945 4d2213c6527d2b2d1838faa39d4ccaa8 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 132 2.0E-56 T 21-04-2016 IPR000037 SsrA-binding protein GO:0003723 HSISS4_RS01415 b8e0c733c58ee8c5c87e1a1ca29e5769 461 PANTHER PTHR32024:SF1 8 461 3.1E-127 T 21-04-2016 HSISS4_RS01415 b8e0c733c58ee8c5c87e1a1ca29e5769 461 PANTHER PTHR32024 8 461 3.1E-127 T 21-04-2016 HSISS4_RS01415 b8e0c733c58ee8c5c87e1a1ca29e5769 461 Pfam PF02386 Cation transport protein 40 444 1.3E-57 T 21-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HSISS4_RS03415 5ffe6f355fe7f6d3309e5794299404d7 440 Pfam PF01476 LysM domain 74 116 1.1E-8 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03415 5ffe6f355fe7f6d3309e5794299404d7 440 SUPERFAMILY SSF54106 73 116 4.05E-8 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03415 5ffe6f355fe7f6d3309e5794299404d7 440 SMART SM00257 73 117 4.5E-8 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03415 5ffe6f355fe7f6d3309e5794299404d7 440 Gene3D G3DSA:3.10.350.10 73 116 6.1E-11 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03325 852174e9e675525b282ea5a8ec6b3884 87 PANTHER PTHR33885 1 66 5.6E-15 T 21-04-2016 HSISS4_RS03325 852174e9e675525b282ea5a8ec6b3884 87 Pfam PF04024 PspC domain 4 59 2.3E-16 T 21-04-2016 IPR007168 Phage shock protein, PspC, N-terminal HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PANTHER PTHR11732:SF10 1 183 2.4E-129 T 21-04-2016 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PANTHER PTHR11732:SF10 200 301 2.4E-129 T 21-04-2016 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 Pfam PF00248 Aldo/keto reductase family 15 298 7.1E-54 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PANTHER PTHR11732 1 183 2.4E-129 T 21-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PANTHER PTHR11732 200 301 2.4E-129 T 21-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 Gene3D G3DSA:3.20.20.100 9 301 1.6E-67 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.0E-7 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PRINTS PR00069 Aldo-keto reductase signature 103 121 4.0E-7 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PRINTS PR00069 Aldo-keto reductase signature 235 259 4.0E-7 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 PRINTS PR00069 Aldo-keto reductase signature 187 216 4.0E-7 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06265 90bb4fd94b85656b9c11b57bb50395af 307 SUPERFAMILY SSF51430 9 299 2.62E-69 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 Pfam PF01381 Helix-turn-helix 7 57 1.0E-13 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 Gene3D G3DSA:1.10.260.40 3 63 1.7E-21 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 PANTHER PTHR10245:SF50 1 69 1.4E-33 T 21-04-2016 HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 SMART SM00530 6 60 8.3E-13 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 PANTHER PTHR10245 1 69 1.4E-33 T 21-04-2016 HSISS4_RS06275 49ec9b279194d929333b0dfddcbaa1fd 69 SUPERFAMILY SSF47413 1 67 4.02E-17 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS01280 ab9419edcbe6e769e70e86d91bbc9f6b 216 Gene3D G3DSA:1.20.144.10 32 199 2.8E-30 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01280 ab9419edcbe6e769e70e86d91bbc9f6b 216 SUPERFAMILY SSF48317 3 211 7.19E-42 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01280 ab9419edcbe6e769e70e86d91bbc9f6b 216 Pfam PF01569 PAP2 superfamily 93 204 1.5E-22 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01280 ab9419edcbe6e769e70e86d91bbc9f6b 216 PANTHER PTHR14969 35 206 1.5E-30 T 21-04-2016 HSISS4_RS01280 ab9419edcbe6e769e70e86d91bbc9f6b 216 SMART SM00014 87 199 1.6E-19 T 21-04-2016 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase HSISS4_RS01140 933dd2edd3de7e580eb8236a03be6ba7 666 Hamap MF_01941 Mid-cell-anchored protein Z [mapZ]. 1 666 26.685 T 21-04-2016 IPR030858 Mid-cell-anchored protein Z GO:0016021|GO:0051301 HSISS4_RS01645 cae901f00c321ab6b9d5b808b40468d9 316 PANTHER PTHR30482:SF10 1 314 7.0E-94 T 21-04-2016 HSISS4_RS01645 cae901f00c321ab6b9d5b808b40468d9 316 Pfam PF02653 Branched-chain amino acid transport system / permease component 36 290 1.4E-40 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS01645 cae901f00c321ab6b9d5b808b40468d9 316 PANTHER PTHR30482 1 314 7.0E-94 T 21-04-2016 HSISS4_RS01000 3ead771557a4e204b5ac6b6d7f1243dc 110 Pfam PF05154 TM2 domain 45 91 2.4E-13 T 21-04-2016 IPR007829 TM2 domain HSISS4_RS01000 3ead771557a4e204b5ac6b6d7f1243dc 110 PANTHER PTHR21016 50 109 3.4E-12 T 21-04-2016 HSISS4_RS01000 3ead771557a4e204b5ac6b6d7f1243dc 110 PANTHER PTHR21016:SF4 50 109 3.4E-12 T 21-04-2016 HSISS4_RS05825 0a4e9c7d31cfc0079a221b749bf20407 310 PANTHER PTHR30040 1 308 1.3E-93 T 21-04-2016 HSISS4_RS05825 0a4e9c7d31cfc0079a221b749bf20407 310 PANTHER PTHR30040:SF2 1 308 1.3E-93 T 21-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 HSISS4_RS05825 0a4e9c7d31cfc0079a221b749bf20407 310 PIRSF PIRSF006268 1 308 1.3E-87 T 21-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 HSISS4_RS05825 0a4e9c7d31cfc0079a221b749bf20407 310 SUPERFAMILY SSF143631 4 306 1.78E-85 T 21-04-2016 IPR003374 ApbE-like domain HSISS4_RS05825 0a4e9c7d31cfc0079a221b749bf20407 310 Pfam PF02424 ApbE family 11 290 3.2E-72 T 21-04-2016 IPR024932 Flavin transferase ApbE GO:0017013 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 Gene3D G3DSA:1.10.8.260 271 317 3.2E-7 T 21-04-2016 IPR023166 HI0933 insert-like domain HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 Gene3D G3DSA:3.50.50.60 2 189 5.9E-47 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 Gene3D G3DSA:3.50.50.60 335 387 5.9E-47 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 SUPERFAMILY SSF51905 333 388 1.46E-49 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 SUPERFAMILY SSF51905 1 191 1.46E-49 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PANTHER PTHR10617 1 292 4.2E-121 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PANTHER PTHR10617 326 387 4.2E-121 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 Gene3D G3DSA:2.40.30.10 192 270 1.2E-23 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 SUPERFAMILY SSF160996 193 336 1.02E-31 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 167 2.9E-6 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-6 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PANTHER PTHR10617:SF103 1 292 4.2E-121 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 PANTHER PTHR10617:SF103 326 387 4.2E-121 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 Pfam PF03486 HI0933-like protein 5 387 2.0E-140 T 21-04-2016 HSISS4_RS07745 eef44cca3439025a6102600e83c2a467 393 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 6 387 1.1E-131 T 21-04-2016 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PIRSF PIRSF000099 2 427 3.9E-169 T 21-04-2016 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 SUPERFAMILY SSF53720 27 424 9.61E-86 T 21-04-2016 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 33 423 1.1E-166 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 Gene3D G3DSA:3.40.50.1980 27 220 6.5E-85 T 21-04-2016 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 Pfam PF00815 Histidinol dehydrogenase 24 423 5.5E-169 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PANTHER PTHR21256 7 427 6.8E-201 T 21-04-2016 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 358 376 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 134 160 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 167 193 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 248 267 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 33 57 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 197 222 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 226 247 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 PRINTS PR00083 Histidinol dehydrogenase signature 317 342 3.0E-91 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 Gene3D G3DSA:3.40.50.1980 221 369 2.0E-66 T 21-04-2016 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 226 258 - T 21-04-2016 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03895 ebda7f23ed67834ecc7ba08a543a198c 427 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 424 43.034 T 21-04-2016 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23|UniPathway: UPA00031 HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 PANTHER PTHR30217 1 428 3.5E-213 T 21-04-2016 HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 ProSitePatterns PS01276 Peptidase family U32 signature. 165 183 - T 21-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 PANTHER PTHR30217:SF6 1 428 3.5E-213 T 21-04-2016 HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 Pfam PF16325 Peptidase family U32 C-terminal domain 326 407 1.8E-21 T 21-04-2016 IPR032525 Peptidase family U32, C-terminal KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 Pfam PF01136 Peptidase family U32 84 311 1.1E-86 T 21-04-2016 IPR001539 Peptidase U32 GO:0006508|GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 Gene3D G3DSA:3.20.20.70 136 161 4.0E-4 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS03360 6c764d3fdf65640ecf83184091414866 428 Gene3D G3DSA:3.20.20.70 13 102 4.0E-4 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS07450 06378e56dbb7606de42db82880d9e5ce 159 Pfam PF06177 QueT transporter 11 153 2.0E-24 T 21-04-2016 IPR010387 Queuosine precursor transporter QueT GO:0005886 HSISS4_RS07450 06378e56dbb7606de42db82880d9e5ce 159 PANTHER PTHR40044:SF1 2 155 5.2E-14 T 21-04-2016 HSISS4_RS07450 06378e56dbb7606de42db82880d9e5ce 159 PANTHER PTHR40044 2 155 5.2E-14 T 21-04-2016 HSISS4_RS06000 ff2fa18e0442d71023712538ee021577 289 PANTHER PTHR30182 1 289 2.1E-128 T 21-04-2016 HSISS4_RS06000 ff2fa18e0442d71023712538ee021577 289 Pfam PF03313 Serine dehydratase alpha chain 19 275 2.5E-72 T 21-04-2016 IPR005130 Serine dehydratase-like, alpha subunit HSISS4_RS06000 ff2fa18e0442d71023712538ee021577 289 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 289 1.6E-105 T 21-04-2016 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17|UniPathway: UPA00138 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 PANTHER PTHR31829 2 290 3.0E-213 T 21-04-2016 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 SUPERFAMILY SSF51366 16 265 1.22E-64 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 Gene3D G3DSA:3.20.20.70 190 277 1.3E-51 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 Gene3D G3DSA:3.20.20.70 22 158 1.3E-51 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 2 290 49.734 T 21-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 7 284 9.3E-152 T 21-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 PIRSF PIRSF029271 1 290 3.8E-145 T 21-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 Pfam PF01680 SOR/SNZ family 6 210 4.0E-107 T 21-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS06575 75e1fd70b9b1e79f2707235f792be7c0 290 ProSitePatterns PS01235 PdxS/SNZ family signature. 203 221 - T 21-04-2016 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466|UniPathway: UPA00245 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 193 35.66 T 21-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 SUPERFAMILY SSF51366 2 191 2.67E-54 T 21-04-2016 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 PANTHER PTHR22854 2 192 2.8E-58 T 21-04-2016 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 189 1.6E-50 T 21-04-2016 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24|UniPathway: UPA00035 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 PANTHER PTHR22854:SF6 2 192 2.8E-58 T 21-04-2016 HSISS4_RS07655 eb8f2645fc7da2f45f6dfc95f42dc53c 193 Gene3D G3DSA:3.20.20.70 2 192 1.7E-65 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 PANTHER PTHR23416 5 176 1.6E-79 T 21-04-2016 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 149 8.2E-4 T 21-04-2016 IPR001451 Hexapeptide repeat HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 5 165 9.6E-69 T 21-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 PANTHER PTHR23416:SF55 5 176 1.6E-79 T 21-04-2016 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 Gene3D G3DSA:2.160.10.10 62 193 5.3E-30 T 21-04-2016 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 Gene3D G3DSA:1.10.3130.10 5 61 3.4E-22 T 21-04-2016 HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 SUPERFAMILY SSF51161 4 174 4.3E-49 T 21-04-2016 IPR011004 Trimeric LpxA-like HSISS4_RS00520 1ae3f49c50d682d6410991d4ba73f670 206 PIRSF PIRSF000441 2 197 5.8E-69 T 21-04-2016 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|UniPathway: UPA00136 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 Pfam PF02833 DHHA2 domain 184 306 9.5E-18 T 21-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 PANTHER PTHR12112 4 310 9.9E-117 T 21-04-2016 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 SMART SM01131 182 308 2.0E-57 T 21-04-2016 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 PANTHER PTHR12112:SF17 4 310 9.9E-117 T 21-04-2016 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 Pfam PF01368 DHH family 3 146 1.6E-24 T 21-04-2016 IPR001667 DDH domain HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 3 310 45.496 T 21-04-2016 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 Gene3D G3DSA:3.90.1640.10 2 188 9.9E-64 T 21-04-2016 HSISS4_RS01740 2c66f8d49eece8077e47eda7f5597909 310 SUPERFAMILY SSF64182 3 308 2.88E-85 T 21-04-2016 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PRINTS PR00069 Aldo-keto reductase signature 165 194 4.6E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PRINTS PR00069 Aldo-keto reductase signature 91 109 4.6E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PRINTS PR00069 Aldo-keto reductase signature 131 148 4.6E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PRINTS PR00069 Aldo-keto reductase signature 35 59 4.6E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PRINTS PR00069 Aldo-keto reductase signature 202 226 4.6E-43 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PANTHER PTHR11732 1 266 1.3E-138 T 21-04-2016 IPR001395 Aldo/keto reductase/potassium channel subunit beta HSISS4_RS06350 83369da2717dea07345130a429f84633 280 Pfam PF00248 Aldo/keto reductase family 14 266 4.6E-53 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS06350 83369da2717dea07345130a429f84633 280 PIRSF PIRSF000097 1 279 1.9E-80 T 21-04-2016 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 HSISS4_RS06350 83369da2717dea07345130a429f84633 280 SUPERFAMILY SSF51430 3 266 7.2E-95 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS06350 83369da2717dea07345130a429f84633 280 Gene3D G3DSA:3.20.20.100 2 273 9.5E-108 T 21-04-2016 IPR023210 NADP-dependent oxidoreductase domain HSISS4_RS05500 6e32e5db10cc2174991c8cd7cfa4dec0 335 Pfam PF03601 Conserved hypothetical protein 698 8 313 3.3E-85 T 21-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 HSISS4_RS05500 6e32e5db10cc2174991c8cd7cfa4dec0 335 PANTHER PTHR30106:SF1 2 335 1.2E-135 T 21-04-2016 HSISS4_RS05500 6e32e5db10cc2174991c8cd7cfa4dec0 335 PANTHER PTHR30106 2 335 1.2E-135 T 21-04-2016 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 HSISS4_RS00335 97c0b1da841760b7e2423003f3ea3ede 184 PANTHER PTHR30037:SF4 1 183 1.9E-92 T 21-04-2016 HSISS4_RS00335 97c0b1da841760b7e2423003f3ea3ede 184 PANTHER PTHR30037 1 183 1.9E-92 T 21-04-2016 HSISS4_RS00335 97c0b1da841760b7e2423003f3ea3ede 184 Gene3D G3DSA:1.10.340.30 3 183 5.7E-77 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS00335 97c0b1da841760b7e2423003f3ea3ede 184 SUPERFAMILY SSF48150 3 183 1.26E-72 T 21-04-2016 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: REACT_216 HSISS4_RS00335 97c0b1da841760b7e2423003f3ea3ede 184 Pfam PF03352 Methyladenine glycosylase 7 183 2.0E-73 T 21-04-2016 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 Gene3D G3DSA:3.40.50.300 1 226 8.1E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 Pfam PF00005 ABC transporter 17 160 1.1E-29 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 SUPERFAMILY SSF52540 2 223 1.97E-60 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 PANTHER PTHR24220:SF160 3 223 2.8E-81 T 21-04-2016 HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 SMART SM00382 26 211 1.6E-9 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07770 92681b9088502db7639b3c118fe3062c 243 PANTHER PTHR24220 3 223 2.8E-81 T 21-04-2016 HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 PANTHER PTHR22572:SF14 8 295 4.4E-111 T 21-04-2016 HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 SUPERFAMILY SSF53448 4 274 2.48E-65 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 6 270 7.8E-110 T 21-04-2016 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343 HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 PANTHER PTHR22572 8 295 4.4E-111 T 21-04-2016 HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 Gene3D G3DSA:3.90.550.10 7 280 3.8E-70 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS08910 e69f14e3dc0852884522a452c4e07ed1 304 Pfam PF00483 Nucleotidyl transferase 8 267 2.4E-33 T 21-04-2016 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 Reactome: REACT_17015 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 8 557 44.905 T 21-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 SUPERFAMILY SSF143975 7 379 1.22E-136 T 21-04-2016 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 20 557 1.0E-216 T 21-04-2016 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 Pfam PF00920 Dehydratase family 37 554 1.1E-209 T 21-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 PANTHER PTHR21000 3 564 0.0 T 21-04-2016 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 SUPERFAMILY SSF52016 381 560 2.67E-56 T 21-04-2016 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 125 135 - T 21-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 PANTHER PTHR21000:SF5 3 564 0.0 T 21-04-2016 HSISS4_RS07740 56529775adfa32c649f64bbbd02bfa7e 567 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 21-04-2016 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 SUPERFAMILY SSF53448 303 545 6.75E-57 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 Gene3D G3DSA:3.90.550.10 302 545 2.1E-56 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 Gene3D G3DSA:3.90.550.10 2 206 4.4E-50 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 Pfam PF01501 Glycosyl transferase family 8 303 525 1.2E-34 T 21-04-2016 IPR002495 Glycosyl transferase, family 8 GO:0016757 HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 PANTHER PTHR22916:SF24 2 469 1.3E-48 T 21-04-2016 HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 SUPERFAMILY SSF53448 4 233 4.42E-49 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 Pfam PF00535 Glycosyl transferase family 2 6 178 3.1E-30 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS06765 2eaf1fa799550eef650cfc29ac1994a1 697 PANTHER PTHR22916 2 469 1.3E-48 T 21-04-2016 HSISS4_RS02315 87cbf941e44bdde193434160a63f92c0 268 PANTHER PTHR21600 87 258 4.2E-36 T 21-04-2016 HSISS4_RS02315 87cbf941e44bdde193434160a63f92c0 268 Pfam PF04468 PSP1 C-terminal conserved region 61 145 1.8E-19 T 21-04-2016 IPR007557 PSP1, C-terminal HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 5 114 29.913 T 21-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 SUPERFAMILY SSF54843 6 114 7.19E-45 T 21-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 9 111 1.4E-45 T 21-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 PANTHER PTHR13501 1 113 7.4E-51 T 21-04-2016 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 Gene3D G3DSA:3.90.470.10 6 114 3.6E-45 T 21-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 ProSitePatterns PS00464 Ribosomal protein L22 signature. 87 111 - T 21-04-2016 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS09325 810726b88fae678ea28caf1174e78768 114 Pfam PF00237 Ribosomal protein L22p/L17e 12 111 1.3E-35 T 21-04-2016 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 Pfam PF00455 DeoR C terminal sensor domain 76 229 1.3E-33 T 21-04-2016 IPR014036 DeoR C-terminal sensor domain HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 21-04-2016 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 Gene3D G3DSA:1.10.10.10 1 48 3.5E-9 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 PANTHER PTHR30363 1 253 4.3E-56 T 21-04-2016 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 SUPERFAMILY SSF100950 76 231 1.15E-16 T 21-04-2016 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 PANTHER PTHR30363:SF13 1 253 4.3E-56 T 21-04-2016 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 SUPERFAMILY SSF46785 4 59 5.24E-10 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 SMART SM00420 6 58 2.5E-13 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 6.2E-7 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 6.2E-7 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 3.3E-16 T 21-04-2016 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 HSISS4_RS01035 07a29d26c0e1892550b4cb91386a9cb2 255 SMART SM01134 72 230 8.3E-43 T 21-04-2016 HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 Gene3D G3DSA:1.10.150.240 17 73 1.1E-23 T 21-04-2016 IPR023198 Phosphoglycolate phosphatase, domain 2 HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 Gene3D G3DSA:3.40.50.1000 74 211 2.4E-42 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 PANTHER PTHR18901:SF23 1 211 2.1E-65 T 21-04-2016 HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 SUPERFAMILY SSF56784 2 210 3.6E-53 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 2.1E-39 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 PANTHER PTHR18901 1 211 2.1E-65 T 21-04-2016 HSISS4_RS05120 1953990a21958febc64567af0e5e3cd0 211 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 175 6.1E-6 T 21-04-2016 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 HSISS4_RS00825 9cbbd4e9ecf433c26d36db25b386def8 855 TIGRFAM TIGR04320 Surf_Exclu_PgrA: SEC10/PgrA surface exclusion domain 260 622 1.6E-82 T 21-04-2016 IPR027607 SEC10/PgrA surface exclusion domain HSISS4_RS00825 9cbbd4e9ecf433c26d36db25b386def8 855 Pfam PF00746 Gram positive anchor 817 848 1.4E-4 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS00825 9cbbd4e9ecf433c26d36db25b386def8 855 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 820 855 6.1E-6 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 311 3.7E-22 T 21-04-2016 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 Gene3D G3DSA:3.30.360.10 155 308 6.1E-54 T 21-04-2016 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 PANTHER PTHR32338 1 340 6.7E-138 T 21-04-2016 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 PANTHER PTHR32338:SF8 1 340 6.7E-138 T 21-04-2016 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 334 40.097 T 21-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 SUPERFAMILY SSF55347 146 308 2.14E-50 T 21-04-2016 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 SMART SM00859 2 140 8.2E-36 T 21-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 21-04-2016 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 107 6.5E-27 T 21-04-2016 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 SUPERFAMILY SSF51735 2 173 2.2E-39 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 Gene3D G3DSA:3.40.50.720 1 154 1.6E-49 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS02165 01ceb9c0cd68609a7da9c08c6b7cd931 340 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 338 5.7E-121 T 21-04-2016 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400|UniPathway: UPA00068 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 14 381 7.7E-112 T 21-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 168 186 4.1E-6 T 21-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 76 96 4.1E-6 T 21-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 49 70 4.1E-6 T 21-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 Gene3D G3DSA:3.90.770.10 228 369 6.1E-90 T 21-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 Gene3D G3DSA:3.90.770.10 5 115 6.1E-90 T 21-04-2016 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 SUPERFAMILY SSF56542 223 422 1.57E-103 T 21-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 SUPERFAMILY SSF56542 6 118 1.57E-103 T 21-04-2016 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 SUPERFAMILY SSF55035 111 214 6.02E-32 T 21-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 PANTHER PTHR10572 5 422 3.7E-137 T 21-04-2016 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 7 380 3.7E-96 T 21-04-2016 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 Gene3D G3DSA:3.30.70.420 116 214 3.9E-38 T 21-04-2016 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|UniPathway: UPA00058 HSISS4_RS02705 8b1d018927c0620b153ec4422230cd3d 423 PANTHER PTHR10572:SF13 5 422 3.7E-137 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 220 227 - T 21-04-2016 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 Gene3D G3DSA:3.40.190.10 90 165 1.4E-25 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 Gene3D G3DSA:3.30.70.260 191 267 7.1E-25 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 Pfam PF00800 Prephenate dehydratase 3 178 8.9E-60 T 21-04-2016 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432|UniPathway: UPA00121 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 SUPERFAMILY SSF53850 1 181 4.07E-54 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 SUPERFAMILY SSF55021 173 270 1.68E-23 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 Gene3D G3DSA:3.40.190.10 2 89 2.7E-28 T 21-04-2016 HSISS4_RS03050 0a4ca8c5ffa33dd142075db0e40a0fae 274 PANTHER PTHR21022 3 274 3.8E-99 T 21-04-2016 HSISS4_RS03465 4b0619d3cb778cd59ac187789ed1c9ce 385 Gene3D G3DSA:3.40.50.1820 106 283 3.9E-5 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03465 4b0619d3cb778cd59ac187789ed1c9ce 385 Pfam PF11187 Protein of unknown function (DUF2974) 80 305 3.0E-68 T 21-04-2016 IPR024499 Protein of unknown function DUF2974 HSISS4_RS03465 4b0619d3cb778cd59ac187789ed1c9ce 385 SUPERFAMILY SSF53474 114 259 6.34E-11 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03720 7a468a546e142724e8ce10b1a3413f26 275 Gene3D G3DSA:3.40.50.1820 11 271 2.0E-46 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03720 7a468a546e142724e8ce10b1a3413f26 275 SUPERFAMILY SSF53474 4 272 7.5E-41 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03720 7a468a546e142724e8ce10b1a3413f26 275 Pfam PF00756 Putative esterase 20 268 1.0E-21 T 21-04-2016 IPR000801 Putative esterase HSISS4_RS03720 7a468a546e142724e8ce10b1a3413f26 275 PANTHER PTHR10907:SF58 18 209 5.9E-68 T 21-04-2016 HSISS4_RS03720 7a468a546e142724e8ce10b1a3413f26 275 PANTHER PTHR10907 18 209 5.9E-68 T 21-04-2016 HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 21-04-2016 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 PANTHER PTHR10584:SF170 1 78 3.4E-30 T 21-04-2016 HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 SUPERFAMILY SSF53613 1 78 1.19E-21 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 PANTHER PTHR10584 1 78 3.4E-30 T 21-04-2016 HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 Gene3D G3DSA:3.40.1190.20 1 78 9.2E-19 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS09510 474e591cdf54c5d66c3f202b700101e0 79 Pfam PF00294 pfkB family carbohydrate kinase 13 78 9.5E-12 T 21-04-2016 IPR011611 Carbohydrate kinase PfkB HSISS4_RS07285 0b5ce762f21863ff45ded1828ad41e40 124 Pfam PF03788 LrgA family 15 107 9.7E-28 T 21-04-2016 IPR005538 LrgA/CidA family GO:0016021 HSISS4_RS07285 0b5ce762f21863ff45ded1828ad41e40 124 PANTHER PTHR33931 1 112 2.5E-27 T 21-04-2016 HSISS4_RS07285 0b5ce762f21863ff45ded1828ad41e40 124 PANTHER PTHR33931:SF2 1 112 2.5E-27 T 21-04-2016 HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 SMART SM00855 3 154 1.2E-18 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 PANTHER PTHR23029:SF38 2 198 5.9E-58 T 21-04-2016 HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 Gene3D G3DSA:3.40.50.1240 1 190 4.0E-45 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 21-04-2016 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 UniPathway: UPA00109 HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 PANTHER PTHR23029 2 198 5.9E-58 T 21-04-2016 HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 SUPERFAMILY SSF53254 1 187 3.27E-45 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS04675 1000f1d9ef7d229ff961218cfcf7cc66 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 189 1.8E-36 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS05875 87d0818cff55eb8bf6b70298f9e965d3 176 Pfam PF07155 ECF-type riboflavin transporter, S component 5 168 3.1E-20 T 21-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 SUPERFAMILY SSF52540 117 265 1.36E-17 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 PANTHER PTHR30050:SF8 27 300 5.3E-94 T 21-04-2016 HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 Pfam PF07319 Primosomal protein DnaI N-terminus 1 90 2.7E-22 T 21-04-2016 IPR009928 Primosomal DnaI, N-terminal HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 Pfam PF01695 IstB-like ATP binding protein 151 267 1.3E-12 T 21-04-2016 IPR002611 IstB-like ATP-binding protein GO:0005524 HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 Gene3D G3DSA:3.40.50.300 101 289 9.3E-36 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01450 e4d1960493133d50d2f1f1f5d9c71e24 300 PANTHER PTHR30050 27 300 5.3E-94 T 21-04-2016 HSISS4_RS02850 9a171bff8cfd00b5942153fa89585cad 76 SUPERFAMILY SSF143567 3 76 6.93E-24 T 21-04-2016 HSISS4_RS02850 9a171bff8cfd00b5942153fa89585cad 76 PIRSF PIRSF037356 1 76 1.7E-31 T 21-04-2016 IPR014904 Protein of unknown function DUF1797 HSISS4_RS02850 9a171bff8cfd00b5942153fa89585cad 76 Pfam PF08796 Protein of unknown function (DUF1797) 8 75 1.8E-24 T 21-04-2016 IPR014904 Protein of unknown function DUF1797 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 Gene3D G3DSA:3.40.190.10 232 269 2.0E-34 T 21-04-2016 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 Gene3D G3DSA:3.40.190.10 47 128 2.0E-34 T 21-04-2016 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 Gene3D G3DSA:3.40.190.10 129 231 5.4E-24 T 21-04-2016 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 PANTHER PTHR18966 46 266 2.1E-23 T 21-04-2016 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 SMART SM00062 50 271 7.2E-52 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 268 6.8E-47 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 SUPERFAMILY SSF53850 13 270 4.04E-56 T 21-04-2016 HSISS4_RS04345 d3e444f80ebafc3266f226b94248027f 277 PANTHER PTHR18966:SF191 46 266 2.1E-23 T 21-04-2016 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 Gene3D G3DSA:2.40.50.40 141 208 2.3E-16 T 21-04-2016 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 PANTHER PTHR26402 2 226 1.4E-15 T 21-04-2016 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 SUPERFAMILY SSF52172 1 133 3.42E-8 T 21-04-2016 IPR011006 CheY-like superfamily HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 SMART SM00850 149 243 3.5E-20 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 Gene3D G3DSA:3.40.50.2300 2 140 5.0E-11 T 21-04-2016 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 Pfam PF04397 LytTr DNA-binding domain 152 242 3.6E-19 T 21-04-2016 IPR007492 LytTR DNA-binding domain GO:0003677 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 Pfam PF00072 Response regulator receiver domain 4 123 1.9E-8 T 21-04-2016 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 Reactome: REACT_14797 HSISS4_RS07415 42ddb294bf2ce44510fa44344cc7ac32 245 PANTHER PTHR26402:SF472 2 226 1.4E-15 T 21-04-2016 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 Pfam PF01084 Ribosomal protein S18 22 73 7.6E-29 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 78 5.0E-25 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 SUPERFAMILY SSF46911 6 78 1.57E-30 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.4E-20 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.4E-20 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.4E-20 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.4E-20 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 77 1.6E-31 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 26 49 - T 21-04-2016 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 78 22.443 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 PANTHER PTHR13479 10 79 6.7E-33 T 21-04-2016 HSISS4_RS08440 e046ad716f2f9d235a1a276ae8f9de49 79 Gene3D G3DSA:4.10.640.10 13 78 5.2E-34 T 21-04-2016 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS07765 cc59f568237d8ecda024fc5f1176f37d 345 Pfam PF05975 Bacterial ABC transporter protein EcsB 158 330 3.3E-41 T 21-04-2016 IPR010288 Bacterial ABC transporter EcsB GO:0016021 HSISS4_RS07765 cc59f568237d8ecda024fc5f1176f37d 345 Pfam PF05975 Bacterial ABC transporter protein EcsB 4 160 1.0E-32 T 21-04-2016 IPR010288 Bacterial ABC transporter EcsB GO:0016021 HSISS4_RS07765 cc59f568237d8ecda024fc5f1176f37d 345 PANTHER PTHR41253 1 345 3.3E-29 T 21-04-2016 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 327 1.2E-133 T 21-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 PIRSF PIRSF000116 2 324 2.4E-51 T 21-04-2016 IPR014359 Ketol-acid reductoisomerase, bacteria GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 184 326 1.3E-63 T 21-04-2016 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 178 3.3E-75 T 21-04-2016 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 Gene3D G3DSA:3.50.50.60 9 38 3.1E-4 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 SUPERFAMILY SSF48179 184 331 5.44E-67 T 21-04-2016 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 Gene3D G3DSA:1.10.1040.10 39 326 4.1E-110 T 21-04-2016 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 Hamap MF_00435 Ketol-acid reductoisomerase [ilvC]. 3 329 43.965 T 21-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 SUPERFAMILY SSF51735 4 183 2.26E-69 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS09105 eb88fafebd74fc7097a5013700ab2d75 340 PANTHER PTHR21371 7 338 2.8E-188 T 21-04-2016 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111|UniPathway: UPA00047|UniPathway: UPA00049 HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 Gene3D G3DSA:1.10.287.130 174 231 2.4E-6 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 PANTHER PTHR40448:SF1 7 391 2.4E-57 T 21-04-2016 HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 Gene3D G3DSA:3.30.565.10 253 379 1.5E-9 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 Pfam PF14501 GHKL domain 284 387 6.6E-15 T 21-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 SUPERFAMILY SSF55874 254 368 4.96E-10 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS07410 d9a83bba6056adb0dac3e611a2fb4c6f 392 PANTHER PTHR40448 7 391 2.4E-57 T 21-04-2016 HSISS4_RS08415 b53dd8d192c7bebd5ff891af719dfff1 80 Pfam PF13061 Protein of unknown function (DUF3923) 4 68 1.6E-18 T 21-04-2016 IPR025037 Protein of unknown function DUF3923 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627 21 133 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627 187 478 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627 497 700 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 SUPERFAMILY SSF56601 336 701 1.11E-55 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 Gene3D G3DSA:3.40.710.10 335 701 9.8E-60 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627:SF2 21 133 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627:SF2 187 478 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 PANTHER PTHR30627:SF2 497 700 1.7E-139 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 SUPERFAMILY SSF56519 73 138 6.67E-30 T 21-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 SUPERFAMILY SSF56519 205 335 6.67E-30 T 21-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 Gene3D G3DSA:3.90.1310.10 219 334 7.9E-26 T 21-04-2016 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 Pfam PF03717 Penicillin-binding Protein dimerisation domain 80 318 3.8E-34 T 21-04-2016 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 HSISS4_RS02890 2a29881a2fc4de2300cabfabc1c625ed 704 Pfam PF00905 Penicillin binding protein transpeptidase domain 367 698 2.4E-73 T 21-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 PANTHER PTHR11751:SF21 5 384 3.3E-121 T 21-04-2016 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 PANTHER PTHR11751 5 384 3.3E-121 T 21-04-2016 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 Pfam PF00155 Aminotransferase class I and II 31 378 2.6E-45 T 21-04-2016 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 Gene3D G3DSA:3.40.640.10 42 250 1.2E-53 T 21-04-2016 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 Gene3D G3DSA:3.90.1150.10 251 386 2.4E-36 T 21-04-2016 IPR015422 Pyridoxal phosphate-dependent transferase, major region, subdomain 2 GO:0003824 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 TIGRFAM TIGR04350 C_S_lyase_PatB: putative C-S lyase 6 383 4.7E-119 T 21-04-2016 IPR027619 Putative C-S lyase KEGG: 00270+4.4.1.8|KEGG: 00450+4.4.1.8|MetaCyc: PWY-6936 HSISS4_RS01600 391462c79b65c9b6146bdbc8d571989a 387 SUPERFAMILY SSF53383 5 385 1.24E-95 T 21-04-2016 IPR015424 Pyridoxal phosphate-dependent transferase HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 SMART SM00954 44 165 1.6E-40 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 PANTHER PTHR21262:SF11 1 203 8.1E-119 T 21-04-2016 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 SUPERFAMILY SSF81301 3 198 2.29E-57 T 21-04-2016 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 Gene3D G3DSA:3.30.460.10 3 145 6.8E-39 T 21-04-2016 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 2.6E-36 T 21-04-2016 IPR007685 RelA/SpoT GO:0015969 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 Gene3D G3DSA:1.10.287.860 148 202 7.2E-25 T 21-04-2016 HSISS4_RS07025 e39657015cf3f6a5515970566a04a337 224 PANTHER PTHR21262 1 203 8.1E-119 T 21-04-2016 HSISS4_RS03170 a5bdf3a043eba406b62e542a1d872ce7 415 Pfam PF15983 Domain of unknown function (DUF4767) 272 412 1.5E-25 T 21-04-2016 IPR031927 Domain of unknown function DUF4767 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 PANTHER PTHR11496:SF57 1 361 1.6E-172 T 21-04-2016 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 SUPERFAMILY SSF56796 1 356 1.96E-88 T 21-04-2016 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 PIRSF PIRSF000112 1 361 1.6E-100 T 21-04-2016 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 Pfam PF00465 Iron-containing alcohol dehydrogenase 7 348 5.7E-64 T 21-04-2016 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 240 260 - T 21-04-2016 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 PANTHER PTHR11496 1 361 1.6E-172 T 21-04-2016 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 Gene3D G3DSA:3.40.50.1970 1 157 3.3E-42 T 21-04-2016 HSISS4_RS06445 fb5c316742b39a1cbd5bfb9e6ba0d1e5 363 Gene3D G3DSA:1.20.1090.10 159 359 1.9E-67 T 21-04-2016 HSISS4_RS06905 4dda157f7e1156ab4752fd978fbb96ce 232 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 115 229 5.2E-32 T 21-04-2016 IPR024425 Cell wall-active antibiotics response 4TMS YvqF HSISS4_RS06905 4dda157f7e1156ab4752fd978fbb96ce 232 PIRSF PIRSF031509 1 232 4.4E-77 T 21-04-2016 IPR016975 Cell wall-active antibiotic response protein GO:0016021 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 SMART SM00530 5 60 2.2E-15 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 PANTHER PTHR10245:SF56 1 66 9.7E-34 T 21-04-2016 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 PANTHER PTHR10245 1 66 9.7E-34 T 21-04-2016 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 Gene3D G3DSA:1.10.260.40 5 65 7.6E-22 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 SUPERFAMILY SSF47413 5 65 4.56E-18 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS00560 5588b97fc81dd8711f2490e91cb7403d 66 Pfam PF01381 Helix-turn-helix 7 60 3.8E-17 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS00840 0506cf68482a2cd3c0c36ee58d5705db 284 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 8 277 17.6 T 21-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HSISS4_RS00840 0506cf68482a2cd3c0c36ee58d5705db 284 PANTHER PTHR30622 6 284 5.2E-131 T 21-04-2016 HSISS4_RS00840 0506cf68482a2cd3c0c36ee58d5705db 284 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 13 270 2.7E-68 T 21-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HSISS4_RS00840 0506cf68482a2cd3c0c36ee58d5705db 284 Pfam PF02673 Bacitracin resistance protein BacA 13 272 3.2E-80 T 21-04-2016 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 HSISS4_RS00840 0506cf68482a2cd3c0c36ee58d5705db 284 PANTHER PTHR30622:SF5 6 284 5.2E-131 T 21-04-2016 HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 SMART SM00382 32 215 2.0E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 Gene3D G3DSA:3.40.50.300 6 231 2.0E-53 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 PANTHER PTHR24220 7 230 5.4E-47 T 21-04-2016 HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 SUPERFAMILY SSF52540 5 228 4.63E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08245 d4452b355b8cc0be83527c4ef4b2462a 261 Pfam PF00005 ABC transporter 24 166 1.7E-24 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01245 30f1267992aa1f17f21a715518be813f 237 PANTHER PTHR33969 1 233 3.1E-63 T 21-04-2016 HSISS4_RS01245 30f1267992aa1f17f21a715518be813f 237 Hamap MF_01805 Segregation and condensation protein A [scpA]. 1 234 25.061 T 21-04-2016 IPR003768 Segregation and condensation protein A HSISS4_RS01245 30f1267992aa1f17f21a715518be813f 237 PANTHER PTHR33969:SF2 1 233 3.1E-63 T 21-04-2016 HSISS4_RS01245 30f1267992aa1f17f21a715518be813f 237 Pfam PF02616 Segregation and condensation protein ScpA 18 228 2.1E-24 T 21-04-2016 IPR003768 Segregation and condensation protein A HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 PANTHER PTHR11776 1 168 2.3E-76 T 21-04-2016 HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 37.785 T 21-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 SUPERFAMILY SSF53271 6 167 5.4E-49 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 Gene3D G3DSA:3.40.50.2020 2 169 1.4E-64 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 Pfam PF00156 Phosphoribosyl transferase domain 36 167 4.3E-17 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 PANTHER PTHR11776:SF0 1 168 2.3E-76 T 21-04-2016 HSISS4_RS04030 7e0752d509b2d1ecfdc1c9f614276dc1 172 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 169 9.9E-67 T 21-04-2016 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|UniPathway: UPA00588 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 3.4E-18 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 PANTHER PTHR30346 1 292 7.6E-44 T 21-04-2016 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 Gene3D G3DSA:1.10.10.10 1 80 5.2E-24 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 SUPERFAMILY SSF53850 98 298 1.99E-15 T 21-04-2016 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 SUPERFAMILY SSF46785 1 85 4.31E-20 T 21-04-2016 IPR011991 Winged helix-turn-helix DNA-binding domain HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.9E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.9E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.9E-7 T 21-04-2016 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 PANTHER PTHR30346:SF0 1 292 7.6E-44 T 21-04-2016 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 Gene3D G3DSA:3.40.190.10 98 203 1.2E-10 T 21-04-2016 HSISS4_RS02435 c3b350c413e20dfdca8049ef764a2a1e 301 Pfam PF03466 LysR substrate binding domain 99 288 8.7E-12 T 21-04-2016 IPR005119 LysR, substrate-binding HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Pfam PF08903 Domain of unknown function (DUF1846) 5 492 9.9E-241 T 21-04-2016 IPR014999 Uncharacterised protein family UPF0371 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Gene3D G3DSA:1.20.1570.10 208 246 1.7E-50 T 21-04-2016 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Gene3D G3DSA:1.20.1570.10 283 340 1.7E-50 T 21-04-2016 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Hamap MF_01567 UPF0371 protein . 2 494 59.524 T 21-04-2016 IPR014999 Uncharacterised protein family UPF0371 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Gene3D G3DSA:3.10.630.10 253 282 8.7E-128 T 21-04-2016 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 Gene3D G3DSA:3.10.630.10 1 207 8.7E-128 T 21-04-2016 HSISS4_RS06435 c83549b7ae7f0a9f156ac8f5cb48013a 494 PIRSF PIRSF033132 2 494 1.1E-259 T 21-04-2016 IPR014999 Uncharacterised protein family UPF0371 HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 SMART SM00854 54 302 8.6E-93 T 21-04-2016 IPR019079 Capsule synthesis protein, CapA HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 PANTHER PTHR33393 11 303 1.3E-45 T 21-04-2016 HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 55 302 7.5E-71 T 21-04-2016 IPR019079 Capsule synthesis protein, CapA HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 Gene3D G3DSA:3.60.21.10 49 399 4.7E-23 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 PANTHER PTHR33393:SF2 11 303 1.3E-45 T 21-04-2016 HSISS4_RS00635 67a115d92cd6d38f493f4ecbab5f80be 405 SUPERFAMILY SSF56300 54 309 8.63E-40 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 Gene3D G3DSA:2.60.200.30 128 246 9.8E-31 T 21-04-2016 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 PANTHER PTHR20275 45 272 4.6E-51 T 21-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 Hamap MF_00361 NAD kinase [nadK]. 11 274 24.933 T 21-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 Pfam PF01513 ATP-NAD kinase 45 237 8.9E-22 T 21-04-2016 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 Gene3D G3DSA:3.40.50.10330 33 127 1.3E-18 T 21-04-2016 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269 HSISS4_RS07020 33f750a579ed9cb1905a9032152a8795 278 SUPERFAMILY SSF111331 38 272 1.13E-60 T 21-04-2016 IPR016064 NAD kinase/diacylglycerol kinase-like domain HSISS4_RS03370 a6a6118d694e39d4398383da5f6cc2cc 179 Pfam PF02632 BioY family 30 168 2.8E-36 T 21-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HSISS4_RS03370 a6a6118d694e39d4398383da5f6cc2cc 179 PIRSF PIRSF016661 1 178 8.1E-49 T 21-04-2016 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 HSISS4_RS03370 a6a6118d694e39d4398383da5f6cc2cc 179 PANTHER PTHR34295:SF1 1 179 1.1E-46 T 21-04-2016 HSISS4_RS03370 a6a6118d694e39d4398383da5f6cc2cc 179 PANTHER PTHR34295 1 179 1.1E-46 T 21-04-2016 HSISS4_RS00600 a46a7cb09066818aa8d595cafb6dc352 59 Gene3D G3DSA:4.10.830.10 3 59 1.5E-23 T 21-04-2016 HSISS4_RS00600 a46a7cb09066818aa8d595cafb6dc352 59 SUPERFAMILY SSF57716 6 59 5.84E-19 T 21-04-2016 HSISS4_RS00600 a46a7cb09066818aa8d595cafb6dc352 59 PANTHER PTHR19836 1 59 2.8E-30 T 21-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00600 a46a7cb09066818aa8d595cafb6dc352 59 Pfam PF00253 Ribosomal protein S14p/S29e 8 58 2.8E-21 T 21-04-2016 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 HSISS4_RS00600 a46a7cb09066818aa8d595cafb6dc352 59 ProSitePatterns PS00527 Ribosomal protein S14 signature. 21 43 - T 21-04-2016 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 869 887 1.9E-4 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 234 244 0.76 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 406 423 0.0051 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 591 608 0.0028 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 788 805 0.071 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Pfam PF01473 Putative cell wall binding repeat 272 289 0.28 T 21-04-2016 IPR018337 Cell wall/choline-binding repeat HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 149 266 7.61E-19 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 593 720 3.53E-21 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 717 753 1.4E-5 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 406 584 7.29E-28 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 852 950 7.59E-22 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 281 342 3.8E-22 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 476 533 6.5E-15 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 536 598 1.4E-18 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 353 413 1.7E-12 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 415 473 2.8E-20 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 600 671 2.5E-14 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 159 215 1.1E-21 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 878 939 3.1E-23 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 TIGRFAM TIGR04035 glucan_65_rpt: glucan-binding repeat 674 733 1.1E-19 T 21-04-2016 IPR027636 Glucan-binding repeat KEGG: 00500+2.4.1.5 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 639 716 5.7E-11 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 541 638 5.6E-11 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 364 447 1.9E-11 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 472 540 1.4E-9 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 157 250 1.2E-13 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 278 330 3.0E-11 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 746 886 4.45E-15 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 754 833 3.0E-12 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.10.270.10 852 950 1.3E-18 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 Gene3D G3DSA:2.20.120.10 331 363 2.9E-4 T 21-04-2016 HSISS4_RS06600 ef5c407186050fcb6a221946f0b71fbc 953 SUPERFAMILY SSF69360 271 453 5.26E-27 T 21-04-2016 HSISS4_RS07795 454caeeffc9a97e88cd82f4200ee99c2 84 SUPERFAMILY SSF143011 1 83 2.88E-25 T 21-04-2016 HSISS4_RS07795 454caeeffc9a97e88cd82f4200ee99c2 84 PANTHER PTHR38039:SF1 1 84 2.2E-34 T 21-04-2016 HSISS4_RS07795 454caeeffc9a97e88cd82f4200ee99c2 84 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 3.8E-34 T 21-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 HSISS4_RS07795 454caeeffc9a97e88cd82f4200ee99c2 84 PANTHER PTHR38039 1 84 2.2E-34 T 21-04-2016 HSISS4_RS07795 454caeeffc9a97e88cd82f4200ee99c2 84 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 9.1E-40 T 21-04-2016 IPR009614 Toxin YoeB GO:0004519|GO:0006401 HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 SUPERFAMILY SSF53927 9 141 3.54E-38 T 21-04-2016 IPR016193 Cytidine deaminase-like GO:0003824 HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 PANTHER PTHR11086 3 151 8.1E-47 T 21-04-2016 IPR015517 Deoxycytidylate deaminase-related HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 116 1.3E-26 T 21-04-2016 IPR002125 Cytidine and deoxycytidylate deaminases, zinc-binding GO:0008270 HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 PIRSF PIRSF006019 1 150 1.0E-53 T 21-04-2016 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210 HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 Gene3D G3DSA:3.40.140.10 6 140 1.0E-40 T 21-04-2016 HSISS4_RS08385 ae09621df09eb02f73f9c0fad70ffd8a 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 71 106 - T 21-04-2016 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 HSISS4_RS00040 1d3d0c2b596eaa55bd92a825f70ef1f7 123 PANTHER PTHR40027:SF1 1 119 6.9E-22 T 21-04-2016 HSISS4_RS00040 1d3d0c2b596eaa55bd92a825f70ef1f7 123 PANTHER PTHR40027 1 119 6.9E-22 T 21-04-2016 HSISS4_RS00040 1d3d0c2b596eaa55bd92a825f70ef1f7 123 Pfam PF04977 Septum formation initiator 44 119 4.2E-19 T 21-04-2016 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 HSISS4_RS01085 9f656e808e359790b516e3a63e33748f 320 PANTHER PTHR30572:SF9 42 320 2.6E-93 T 21-04-2016 HSISS4_RS01085 9f656e808e359790b516e3a63e33748f 320 PANTHER PTHR30572 42 320 2.6E-93 T 21-04-2016 HSISS4_RS01085 9f656e808e359790b516e3a63e33748f 320 Pfam PF02687 FtsX-like permease family 194 313 1.3E-18 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS02450 d1d705c5648ce6d23ad2648606c5b1ae 173 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 171 34.892 T 21-04-2016 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 HSISS4_RS02450 d1d705c5648ce6d23ad2648606c5b1ae 173 PANTHER PTHR11608 1 173 7.1E-84 T 21-04-2016 HSISS4_RS02450 d1d705c5648ce6d23ad2648606c5b1ae 173 Gene3D G3DSA:3.40.50.2020 3 166 2.8E-41 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS02450 d1d705c5648ce6d23ad2648606c5b1ae 173 SUPERFAMILY SSF53271 4 165 7.08E-36 T 21-04-2016 IPR029057 Phosphoribosyltransferase-like HSISS4_RS02450 d1d705c5648ce6d23ad2648606c5b1ae 173 Pfam PF00156 Phosphoribosyl transferase domain 4 146 4.0E-23 T 21-04-2016 IPR000836 Phosphoribosyltransferase domain GO:0009116 HSISS4_RS02215 3a13262044e821a7ebf8829f901d78e1 192 SUPERFAMILY SSF50475 9 170 4.32E-23 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS02215 3a13262044e821a7ebf8829f901d78e1 192 Gene3D G3DSA:2.30.110.10 5 164 4.8E-24 T 21-04-2016 IPR012349 FMN-binding split barrel GO:0010181|GO:0016491|GO:0055114 UniPathway: UPA00647 HSISS4_RS02215 3a13262044e821a7ebf8829f901d78e1 192 Pfam PF01613 Flavin reductase like domain 15 135 1.6E-4 T 21-04-2016 IPR002563 Flavin reductase like domain GO:0010181 HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 Gene3D G3DSA:1.20.1250.20 6 184 1.6E-16 T 21-04-2016 HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 Gene3D G3DSA:1.20.1250.20 200 381 2.5E-19 T 21-04-2016 HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 SUPERFAMILY SSF103473 1 383 5.1E-47 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 PANTHER PTHR23523 1 389 1.3E-115 T 21-04-2016 HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 Pfam PF07690 Major Facilitator Superfamily 14 349 1.8E-30 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS03145 ba816a6ede3e1bd62a908aeca2eb8341 390 PANTHER PTHR23523:SF2 1 389 1.3E-115 T 21-04-2016 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 Gene3D G3DSA:3.30.390.10 4 125 5.1E-56 T 21-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PIRSF PIRSF001400 1 431 1.2E-188 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 340 354 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 317 328 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 161 174 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 37 51 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 369 386 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PRINTS PR00148 Enolase signature 107 123 1.7E-45 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 SUPERFAMILY SSF54826 3 138 1.08E-57 T 21-04-2016 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 431 6.0E-207 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 SMART SM01192 139 431 8.9E-214 T 21-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 Gene3D G3DSA:3.20.20.120 128 430 1.1E-135 T 21-04-2016 IPR029065 Enolase C-terminal domain-like HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 SUPERFAMILY SSF51604 139 432 2.97E-127 T 21-04-2016 IPR029065 Enolase C-terminal domain-like HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 ProSitePatterns PS00164 Enolase signature. 340 353 - T 21-04-2016 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 Hamap MF_00318 Enolase [eno]. 2 417 44.53 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 429 3.4E-128 T 21-04-2016 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 SMART SM01193 4 134 4.9E-95 T 21-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 Pfam PF03952 Enolase, N-terminal domain 4 134 1.4E-60 T 21-04-2016 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|UniPathway: UPA00109 HSISS4_RS02985 45c812cef18dae19bb87bc139bf868b5 434 PANTHER PTHR11902 1 431 1.3E-259 T 21-04-2016 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: REACT_474|UniPathway: UPA00109 HSISS4_RS00015 4e37534e3f90921757a023c901494e48 63 PANTHER PTHR38455:SF1 1 63 8.5E-26 T 21-04-2016 HSISS4_RS00015 4e37534e3f90921757a023c901494e48 63 PIRSF PIRSF037263 1 63 2.0E-31 T 21-04-2016 IPR009296 Protein of unknown function DUF951 HSISS4_RS00015 4e37534e3f90921757a023c901494e48 63 PANTHER PTHR38455 1 63 8.5E-26 T 21-04-2016 HSISS4_RS00015 4e37534e3f90921757a023c901494e48 63 Pfam PF06107 Bacterial protein of unknown function (DUF951) 2 63 2.1E-28 T 21-04-2016 IPR009296 Protein of unknown function DUF951 HSISS4_RS07715 9850063fc34883f59e05f5eda87a8956 880 PANTHER PTHR30287 1 230 2.1E-51 T 21-04-2016 HSISS4_RS07715 9850063fc34883f59e05f5eda87a8956 880 PANTHER PTHR30287 322 880 2.1E-51 T 21-04-2016 HSISS4_RS07715 9850063fc34883f59e05f5eda87a8956 880 Pfam PF02687 FtsX-like permease family 349 464 9.0E-10 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS07715 9850063fc34883f59e05f5eda87a8956 880 Pfam PF02687 FtsX-like permease family 755 870 1.5E-12 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS07715 9850063fc34883f59e05f5eda87a8956 880 Pfam PF12704 MacB-like periplasmic core domain 516 691 8.3E-9 T 21-04-2016 IPR025857 MacB-like periplasmic core domain HSISS4_RS03950 5c7c0079b05d1cf878d15e68625c50a6 340 PANTHER PTHR10859:SF84 1 297 1.8E-63 T 21-04-2016 HSISS4_RS03950 5c7c0079b05d1cf878d15e68625c50a6 340 Gene3D G3DSA:3.90.550.10 3 123 3.9E-6 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS03950 5c7c0079b05d1cf878d15e68625c50a6 340 PANTHER PTHR10859 1 297 1.8E-63 T 21-04-2016 HSISS4_RS03950 5c7c0079b05d1cf878d15e68625c50a6 340 Pfam PF00535 Glycosyl transferase family 2 3 133 7.7E-12 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS03950 5c7c0079b05d1cf878d15e68625c50a6 340 SUPERFAMILY SSF53448 3 213 6.03E-21 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 Pfam PF07693 KAP family P-loop domain 30 321 2.0E-40 T 21-04-2016 IPR011646 KAP family P-loop domain HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 Gene3D G3DSA:3.40.50.300 23 221 3.2E-9 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 Pfam PF14088 Domain of unknown function (DUF4268) 443 579 6.1E-10 T 21-04-2016 IPR025364 Domain of unknown function DUF4268 HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 PANTHER PTHR22674 185 272 1.8E-14 T 21-04-2016 HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 SUPERFAMILY SSF52540 25 99 3.74E-16 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00275 16037b0f4f9150d9a84573ada2d0642b 584 SUPERFAMILY SSF52540 148 332 3.74E-16 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 SUPERFAMILY SSF55979 3 127 2.04E-18 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 SMART SM00480 18 373 5.9E-145 T 21-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 SUPERFAMILY SSF55979 135 251 1.22E-22 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 3 126 4.6E-25 T 21-04-2016 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 PANTHER PTHR30478 3 378 3.7E-109 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 3 377 5.4E-90 T 21-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 PIRSF PIRSF000804 2 378 3.1E-96 T 21-04-2016 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 SUPERFAMILY SSF55979 253 377 1.1E-26 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Gene3D G3DSA:3.10.150.10 137 255 7.3E-32 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Gene3D G3DSA:3.10.150.10 3 129 6.6E-21 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Gene3D G3DSA:3.10.150.10 258 378 3.7E-32 T 21-04-2016 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 375 2.5E-26 T 21-04-2016 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS00010 35a2771320287983c30413be5c75e464 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 138 251 6.7E-29 T 21-04-2016 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 HSISS4_RS01640 fd2fdb7d81edf2bdd9eac16583b03f48 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 278 4.5E-53 T 21-04-2016 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 HSISS4_RS01640 fd2fdb7d81edf2bdd9eac16583b03f48 294 PANTHER PTHR11795:SF371 4 294 6.0E-138 T 21-04-2016 HSISS4_RS01640 fd2fdb7d81edf2bdd9eac16583b03f48 294 Gene3D G3DSA:1.10.3470.10 48 210 5.5E-6 T 21-04-2016 IPR029022 ABC transporter, BtuC-like HSISS4_RS01640 fd2fdb7d81edf2bdd9eac16583b03f48 294 PANTHER PTHR11795 4 294 6.0E-138 T 21-04-2016 HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 SUPERFAMILY SSF53474 4 228 1.71E-41 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 Pfam PF00561 alpha/beta hydrolase fold 21 129 3.8E-18 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 Gene3D G3DSA:3.40.50.1820 4 229 7.9E-38 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 3.7E-5 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 3.7E-5 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 3.7E-5 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS03755 19e60139c192d8e50a9dff19a4f14650 239 PANTHER PTHR10992 7 232 1.1E-32 T 21-04-2016 HSISS4_RS05690 022d0a6b6fab49a93b6692d1d32190ad 190 Pfam PF12822 Protein of unknown function (DUF3816) 11 179 1.6E-14 T 21-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 HSISS4_RS02080 d8f7c4afc05b9e934dca298f6da8a452 645 SUPERFAMILY SSF74914 199 554 1.03E-54 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS02080 d8f7c4afc05b9e934dca298f6da8a452 645 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 610 637 1.8E-4 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS02080 d8f7c4afc05b9e934dca298f6da8a452 645 Pfam PF00746 Gram positive anchor 603 637 2.6E-5 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS02080 d8f7c4afc05b9e934dca298f6da8a452 645 Pfam PF08363 Glucan-binding protein C 245 538 3.6E-53 T 21-04-2016 IPR013574 Glucan-binding protein C/Surface antigen I/II, V-domain HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 PANTHER PTHR31223 2 187 8.8E-70 T 21-04-2016 HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 Pfam PF03641 Possible lysine decarboxylase 45 172 4.6E-32 T 21-04-2016 IPR031100 LOG family HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 2 178 7.0E-45 T 21-04-2016 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 SUPERFAMILY SSF102405 1 178 1.98E-52 T 21-04-2016 HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 Gene3D G3DSA:3.40.50.450 2 175 3.5E-53 T 21-04-2016 HSISS4_RS01570 38f145794eac40036ebcb3b2e9aeb02c 187 PANTHER PTHR31223:SF0 2 187 8.8E-70 T 21-04-2016 HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 PANTHER PTHR33279 5 74 1.2E-33 T 21-04-2016 HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 Pfam PF01206 Sulfurtransferase TusA 5 74 5.0E-17 T 21-04-2016 IPR001455 TusA-like domain HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 Gene3D G3DSA:3.30.110.40 4 75 6.0E-20 T 21-04-2016 IPR001455 TusA-like domain HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 SUPERFAMILY SSF64307 4 74 1.1E-18 T 21-04-2016 IPR001455 TusA-like domain HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 PANTHER PTHR33279:SF4 5 74 1.2E-33 T 21-04-2016 HSISS4_RS08975 a89b63991c32b0eb8f20cbd660986559 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 6 30 - T 21-04-2016 IPR001455 TusA-like domain HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 25 1215 16.352 T 21-04-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070:SF14 765 830 2.9E-267 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070:SF14 555 748 2.9E-267 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070:SF14 29 205 2.9E-267 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070:SF14 336 536 2.9E-267 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070:SF14 873 1209 2.9E-267 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.90.320.10 1034 1197 6.8E-15 T 21-04-2016 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 28 1211 0.0 T 21-04-2016 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Pfam PF00580 UvrD/REP helicase N-terminal domain 28 464 6.6E-77 T 21-04-2016 IPR014016 UvrD-like Helicase, ATP-binding domain GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Pfam PF13361 UvrD-like helicase C-terminal domain 478 894 8.4E-29 T 21-04-2016 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070 765 830 2.9E-267 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070 555 748 2.9E-267 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070 29 205 2.9E-267 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070 336 536 2.9E-267 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 PANTHER PTHR11070 873 1209 2.9E-267 T 21-04-2016 IPR000212 DNA helicase, UvrD/REP type GO:0003677|GO:0004003|GO:0005524 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.40.50.300 371 468 4.8E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.40.50.300 27 91 4.8E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.40.50.300 123 186 4.8E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.40.50.300 775 934 7.4E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:3.40.50.300 482 607 7.4E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1058 1194 1.3E-7 T 21-04-2016 HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 SUPERFAMILY SSF52540 361 822 2.35E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 SUPERFAMILY SSF52540 25 199 2.35E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 SUPERFAMILY SSF52540 874 900 2.35E-112 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 SUPERFAMILY SSF52980 1008 1197 3.81E-24 T 21-04-2016 IPR011335 Restriction endonuclease type II-like HSISS4_RS08210 a2ea242caa6dff73082ab8caf286fc1f 1217 Gene3D G3DSA:1.10.486.10 616 764 3.9E-20 T 21-04-2016 HSISS4_RS03220 7cc50830f0b07f7ca0d35764a1c04e02 67 Pfam PF05532 CsbD-like 3 52 1.2E-15 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS03220 7cc50830f0b07f7ca0d35764a1c04e02 67 SUPERFAMILY SSF69047 4 60 2.75E-11 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS03220 7cc50830f0b07f7ca0d35764a1c04e02 67 Gene3D G3DSA:1.10.1470.10 3 63 4.5E-20 T 21-04-2016 IPR008462 CsbD-like HSISS4_RS03220 7cc50830f0b07f7ca0d35764a1c04e02 67 PANTHER PTHR34977 1 67 1.1E-14 T 21-04-2016 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 Pfam PF04055 Radical SAM superfamily 128 294 2.8E-18 T 21-04-2016 IPR007197 Radical SAM GO:0003824|GO:0051536 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 PANTHER PTHR30544:SF5 1 384 1.3E-175 T 21-04-2016 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 PIRSF PIRSF006004 16 386 3.8E-140 T 21-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 Pfam PF13394 4Fe-4S single cluster domain 133 227 5.6E-7 T 21-04-2016 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 SUPERFAMILY SSF102114 120 329 3.4E-15 T 21-04-2016 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 PANTHER PTHR30544 1 384 1.3E-175 T 21-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 24 373 4.2E-133 T 21-04-2016 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 Gene3D G3DSA:3.20.20.70 119 354 5.8E-17 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS08110 f0c290c83710561cfc44dc48457a991f 389 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 25 372 71.384 T 21-04-2016 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 Pfam PF00343 Carbohydrate phosphorylase 78 751 6.9E-259 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 PANTHER PTHR11468:SF3 45 751 8.6E-285 T 21-04-2016 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 PIRSF PIRSF000460 6 753 7.3E-193 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 Gene3D G3DSA:3.40.50.2000 12 421 5.1E-136 T 21-04-2016 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 SUPERFAMILY SSF53756 8 752 6.83E-250 T 21-04-2016 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 PANTHER PTHR11468 45 751 8.6E-285 T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 21 751 1.2E-266 T 21-04-2016 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 595 607 - T 21-04-2016 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: REACT_474 HSISS4_RS04840 6f7e953ac9c321441319274878ab2b0e 753 Gene3D G3DSA:3.40.50.2000 422 737 2.9E-117 T 21-04-2016 HSISS4_RS07935 89232a5b2468e98081a6fe46e2a20024 246 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 214 245 3.3E-7 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS07935 89232a5b2468e98081a6fe46e2a20024 246 Pfam PF00746 Gram positive anchor 209 244 1.0E-6 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 SMART SM00235 273 422 0.0074 T 21-04-2016 IPR006026 Peptidase, metallopeptidase GO:0006508|GO:0008237|GO:0008270 HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 Gene3D G3DSA:3.40.390.10 253 421 5.7E-20 T 21-04-2016 IPR024079 Metallopeptidase, catalytic domain GO:0008237 HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 SUPERFAMILY SSF55486 272 421 3.08E-21 T 21-04-2016 HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 Pfam PF00413 Matrixin 291 420 8.1E-8 T 21-04-2016 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 PRINTS PR00138 Matrixin signature 297 312 4.97E-5 T 21-04-2016 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 HSISS4_RS07420 463243dc53a85dc6b581313216d69ae8 423 PRINTS PR00138 Matrixin signature 378 403 4.97E-5 T 21-04-2016 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 410 6.4E-105 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 SUPERFAMILY SSF55205 1 421 8.67E-134 T 21-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 PANTHER PTHR21090:SF19 1 422 3.4E-251 T 21-04-2016 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 419 5.2E-161 T 21-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 PANTHER PTHR21090 1 422 3.4E-251 T 21-04-2016 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 420 44.125 T 21-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 Gene3D G3DSA:3.65.10.10 22 223 2.0E-65 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS04320 15db2eb6e6643d9142c958984522e0ea 423 Gene3D G3DSA:3.65.10.10 224 420 1.0E-55 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS01475 7e7848059be6eb60d5e1222b22a0d6a2 303 PANTHER PTHR32502:SF5 1 303 4.3E-160 T 21-04-2016 HSISS4_RS01475 7e7848059be6eb60d5e1222b22a0d6a2 303 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 6 303 5.2E-115 T 21-04-2016 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 HSISS4_RS01475 7e7848059be6eb60d5e1222b22a0d6a2 303 PANTHER PTHR32502 1 303 4.3E-160 T 21-04-2016 HSISS4_RS01630 46cd6ae496c1dfd5ebdfaa665bd53ebc 93 PANTHER PTHR41304:SF1 1 89 1.5E-18 T 21-04-2016 HSISS4_RS01630 46cd6ae496c1dfd5ebdfaa665bd53ebc 93 PIRSF PIRSF031653 1 90 2.4E-31 T 21-04-2016 IPR016979 Protein of unknown function DUF2129 HSISS4_RS01630 46cd6ae496c1dfd5ebdfaa665bd53ebc 93 PANTHER PTHR41304 1 89 1.5E-18 T 21-04-2016 HSISS4_RS01630 46cd6ae496c1dfd5ebdfaa665bd53ebc 93 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 4 73 5.1E-27 T 21-04-2016 IPR016979 Protein of unknown function DUF2129 HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 PANTHER PTHR38448 1 117 1.7E-13 T 21-04-2016 HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 PANTHER PTHR38448:SF1 1 117 1.7E-13 T 21-04-2016 HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 PIRSF PIRSF021287 1 119 5.3E-42 T 21-04-2016 IPR016783 Biofilm formation YmcA HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 SUPERFAMILY SSF158622 6 116 1.06E-24 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 113 5.0E-14 T 21-04-2016 IPR010368 Control of competence regulator ComK, YlbF/YmcA HSISS4_RS00295 67ceff1f7fab83710dff8b12643f036a 119 Gene3D G3DSA:1.20.1500.10 6 118 5.9E-31 T 21-04-2016 IPR023378 YheA/YmcA-like domain HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 Pfam PF09383 NIL domain 278 348 2.1E-17 T 21-04-2016 IPR018449 NIL domain HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 Gene3D G3DSA:3.40.50.300 5 245 1.6E-79 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 SUPERFAMILY SSF52540 5 249 3.75E-77 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 PANTHER PTHR24220:SF549 7 271 1.5E-133 T 21-04-2016 IPR026253 Methionine import ATP-binding protein MetN GO:0005524|GO:0015821|GO:0042626 HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 Pfam PF00005 ABC transporter 25 178 2.8E-33 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 PANTHER PTHR24220 7 271 1.5E-133 T 21-04-2016 HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 SMART SM00382 34 229 3.1E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 SMART SM00930 275 350 1.2E-25 T 21-04-2016 IPR018449 NIL domain HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 SUPERFAMILY SSF55021 268 352 4.12E-19 T 21-04-2016 HSISS4_RS01375 ee0b735d1cec18bd7eba6ecd6cf50328 355 Gene3D G3DSA:3.30.70.260 246 352 1.1E-24 T 21-04-2016 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 SUPERFAMILY SSF75304 423 478 1.16E-105 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 SUPERFAMILY SSF75304 7 390 1.16E-105 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 PANTHER PTHR11895:SF35 420 478 3.5E-110 T 21-04-2016 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 PANTHER PTHR11895:SF35 8 392 3.5E-110 T 21-04-2016 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 ProSitePatterns PS00571 Amidases signature. 148 179 - T 21-04-2016 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 Gene3D G3DSA:3.90.1300.10 5 478 1.2E-99 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 Pfam PF01425 Amidase 25 470 9.3E-73 T 21-04-2016 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 PANTHER PTHR11895 420 478 3.5E-110 T 21-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS04995 b0d4f2c44a653f2ef1926d5f75961838 483 PANTHER PTHR11895 8 392 3.5E-110 T 21-04-2016 IPR000120 Amidase GO:0016884 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 HSISS4_RS08490 57fd5e69f9c1bf72dd45c789ae46bf1d 180 Pfam PF02674 Colicin V production protein 4 163 2.7E-24 T 21-04-2016 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 SUPERFAMILY SSF69593 2 215 1.7E-57 T 21-04-2016 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 SMART SM00563 36 146 1.1E-26 T 21-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 Gene3D G3DSA:3.40.1130.10 3 193 1.3E-19 T 21-04-2016 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 Pfam PF01553 Acyltransferase 24 143 3.7E-19 T 21-04-2016 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 PANTHER PTHR10434:SF21 2 216 1.2E-58 T 21-04-2016 HSISS4_RS07520 150e876f186f718cf8ebb1725ab1ce5b 251 PANTHER PTHR10434 2 216 1.2E-58 T 21-04-2016 HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 Gene3D G3DSA:3.40.630.30 1 188 1.2E-29 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 SUPERFAMILY SSF55729 1 90 7.25E-22 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 SUPERFAMILY SSF55729 117 191 7.25E-22 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 Pfam PF13508 Acetyltransferase (GNAT) domain 59 182 8.5E-10 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 PANTHER PTHR23091 1 81 8.2E-14 T 21-04-2016 HSISS4_RS01995 fb475bf73d06367ec194acfdd589c5dc 207 PANTHER PTHR23091 120 185 8.2E-14 T 21-04-2016 HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 SUPERFAMILY SSF52540 23 199 3.55E-41 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 Gene3D G3DSA:3.40.50.300 12 196 4.8E-47 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 17 199 28.576 T 21-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 Pfam PF01926 50S ribosome-binding GTPase 31 149 4.7E-22 T 21-04-2016 IPR006073 GTP binding domain GO:0005525 HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 31 195 3.1E-12 T 21-04-2016 IPR005225 Small GTP-binding protein domain GO:0005525 HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 13 195 3.9E-73 T 21-04-2016 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0000917|GO:0005525 HSISS4_RS02730 3fbf1110756fcbf722278cb1ab14b199 199 PANTHER PTHR11649 4 199 2.1E-57 T 21-04-2016 HSISS4_RS03995 3b3a01121404c9a68289574a9d4ab5c0 475 Pfam PF01098 Cell cycle protein 17 385 3.5E-77 T 21-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HSISS4_RS03995 3b3a01121404c9a68289574a9d4ab5c0 475 PANTHER PTHR30474:SF1 10 402 2.4E-121 T 21-04-2016 IPR011923 Rod shape-determining protein RodA GO:0008360|GO:0016021 HSISS4_RS03995 3b3a01121404c9a68289574a9d4ab5c0 475 PANTHER PTHR30474 10 402 2.4E-121 T 21-04-2016 IPR001182 Cell cycle protein FtsW/RodA GO:0016021|GO:0051301 HSISS4_RS03995 3b3a01121404c9a68289574a9d4ab5c0 475 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 343 367 - T 21-04-2016 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 6 350 1.4E-127 T 21-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 2 439 28.366 T 21-04-2016 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 PANTHER PTHR30008:SF0 1 441 3.9E-156 T 21-04-2016 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 Pfam PF02601 Exonuclease VII, large subunit 122 436 3.0E-96 T 21-04-2016 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 Pfam PF13742 OB-fold nucleic acid binding domain 5 97 2.9E-24 T 21-04-2016 IPR025824 OB-fold nucleic acid binding domain GO:0003676 HSISS4_RS04055 dbf759a1b543640f528a1efd37a35dbb 442 PANTHER PTHR30008 1 441 3.9E-156 T 21-04-2016 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 408 1.8E-87 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 Gene3D G3DSA:3.65.10.10 21 222 2.1E-59 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 Gene3D G3DSA:3.65.10.10 223 417 1.4E-58 T 21-04-2016 IPR001986 Enolpyruvate transferase domain GO:0016765 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 41.162 T 21-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 PANTHER PTHR21090 1 420 6.6E-170 T 21-04-2016 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 SUPERFAMILY SSF55205 1 419 1.21E-130 T 21-04-2016 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 HSISS4_RS07505 93cd064961f7afdf1f997d5222ddf73d 420 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 1.9E-153 T 21-04-2016 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|UniPathway: UPA00219 HSISS4_RS04655 fc46bff75b4aa89edd9179677772d64f 350 SUPERFAMILY SSF53756 47 319 1.41E-7 T 21-04-2016 HSISS4_RS04655 fc46bff75b4aa89edd9179677772d64f 350 PIRSF PIRSF007023 1 350 2.6E-135 T 21-04-2016 IPR016503 UDP-galactofuranosyltransferase GO:0016757 HSISS4_RS05110 0c175a3d8e26a96f72a399cb28e08595 322 PANTHER PTHR30532 1 319 1.1E-50 T 21-04-2016 HSISS4_RS05110 0c175a3d8e26a96f72a399cb28e08595 322 Gene3D G3DSA:3.40.50.1980 44 172 5.7E-28 T 21-04-2016 HSISS4_RS05110 0c175a3d8e26a96f72a399cb28e08595 322 Gene3D G3DSA:3.40.50.1980 174 317 3.5E-22 T 21-04-2016 HSISS4_RS05110 0c175a3d8e26a96f72a399cb28e08595 322 SUPERFAMILY SSF53807 46 315 6.28E-52 T 21-04-2016 HSISS4_RS05110 0c175a3d8e26a96f72a399cb28e08595 322 Pfam PF01497 Periplasmic binding protein 63 295 1.2E-26 T 21-04-2016 IPR002491 ABC transporter periplasmic binding domain GO:0005488 HSISS4_RS05930 2626e113b3b09ba66efa1640b0dfd5f0 181 Pfam PF11683 Protein of unknown function (DUF3278) 1 123 1.4E-32 T 21-04-2016 IPR021697 Protein of unknown function DUF3278 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 ProSitePatterns PS01244 Aconitase family signature 2. 392 405 - T 21-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 SUPERFAMILY SSF53732 3 458 3.92E-161 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 459 56.54 T 21-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 Pfam PF00330 Aconitase family (aconitate hydratase) 8 450 8.5E-145 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 Gene3D G3DSA:3.40.1060.10 166 281 5.7E-39 T 21-04-2016 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 336 347 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 392 405 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 119 132 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 209 222 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 133 148 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 195 208 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 286 300 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 108 116 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PRINTS PR00415 Aconitase family signature 82 95 1.7E-45 T 21-04-2016 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 ProSitePatterns PS00450 Aconitase family signature 1. 332 348 - T 21-04-2016 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PANTHER PTHR11670 1 463 3.5E-226 T 21-04-2016 IPR015937 Aconitase/isopropylmalate dehydratase GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 PANTHER PTHR11670:SF12 1 463 3.5E-226 T 21-04-2016 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 Gene3D G3DSA:3.30.499.10 9 164 3.5E-21 T 21-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 Gene3D G3DSA:3.30.499.10 320 458 5.3E-58 T 21-04-2016 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS04135 acb9f6b56893815571b55e5530410222 463 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 458 8.7E-206 T 21-04-2016 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33|UniPathway: UPA00048 HSISS4_RS09215 e90a590f2af039aa8f93824c72aa59c4 431 SUPERFAMILY SSF55931 309 427 9.81E-39 T 21-04-2016 HSISS4_RS09215 e90a590f2af039aa8f93824c72aa59c4 431 SUPERFAMILY SSF55931 15 257 9.81E-39 T 21-04-2016 HSISS4_RS09215 e90a590f2af039aa8f93824c72aa59c4 431 PANTHER PTHR34378:SF2 1 424 8.9E-89 T 21-04-2016 HSISS4_RS09215 e90a590f2af039aa8f93824c72aa59c4 431 PANTHER PTHR34378 1 424 8.9E-89 T 21-04-2016 HSISS4_RS04365 dc494e933db8944c215f350fa7077dc1 232 PANTHER PTHR30614 16 223 7.0E-67 T 21-04-2016 HSISS4_RS04365 dc494e933db8944c215f350fa7077dc1 232 SUPERFAMILY SSF161098 25 217 1.57E-40 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04365 dc494e933db8944c215f350fa7077dc1 232 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 219 3.6E-21 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04365 dc494e933db8944c215f350fa7077dc1 232 Gene3D G3DSA:1.10.3720.10 21 224 3.8E-45 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04365 dc494e933db8944c215f350fa7077dc1 232 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 23 122 8.6E-23 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS07180 3c256e03b255a9d67b97444e44be4bc6 154 PANTHER PTHR22769 12 154 1.2E-26 T 21-04-2016 HSISS4_RS07180 3c256e03b255a9d67b97444e44be4bc6 154 PANTHER PTHR22769:SF30 12 154 1.2E-26 T 21-04-2016 HSISS4_RS07180 3c256e03b255a9d67b97444e44be4bc6 154 Gene3D G3DSA:3.90.79.10 2 153 2.0E-28 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS07180 3c256e03b255a9d67b97444e44be4bc6 154 Pfam PF00293 NUDIX domain 13 129 1.1E-17 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS07180 3c256e03b255a9d67b97444e44be4bc6 154 SUPERFAMILY SSF55811 3 141 5.55E-28 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS08170 e250002d15fe6482a442acd8e77aafdf 132 Pfam PF05656 Protein of unknown function (DUF805) 12 119 1.3E-15 T 21-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 HSISS4_RS08170 e250002d15fe6482a442acd8e77aafdf 132 PANTHER PTHR34980 1 116 1.7E-12 T 21-04-2016 HSISS4_RS08170 e250002d15fe6482a442acd8e77aafdf 132 PANTHER PTHR34980:SF2 1 116 1.7E-12 T 21-04-2016 HSISS4_RS02970 2fd0d5fe66abb83095c9f8d96253a778 355 PANTHER PTHR35145 78 234 2.4E-33 T 21-04-2016 HSISS4_RS02970 2fd0d5fe66abb83095c9f8d96253a778 355 Pfam PF04237 YjbR 123 220 4.5E-15 T 21-04-2016 IPR007351 Uncharacterised protein YjbR HSISS4_RS02970 2fd0d5fe66abb83095c9f8d96253a778 355 PANTHER PTHR35145:SF1 78 234 2.4E-33 T 21-04-2016 HSISS4_RS02970 2fd0d5fe66abb83095c9f8d96253a778 355 SUPERFAMILY SSF142906 105 239 5.89E-27 T 21-04-2016 HSISS4_RS03515 dade1d82609ca5ae2094c02652cbb43b 311 PANTHER PTHR41317:SF1 3 311 2.1E-15 T 21-04-2016 HSISS4_RS03515 dade1d82609ca5ae2094c02652cbb43b 311 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 13 307 7.1E-28 T 21-04-2016 IPR010106 Conserved hypothetical protein CHP01784 HSISS4_RS03515 dade1d82609ca5ae2094c02652cbb43b 311 PANTHER PTHR41317 3 311 2.1E-15 T 21-04-2016 HSISS4_RS03515 dade1d82609ca5ae2094c02652cbb43b 311 Pfam PF12784 PD-(D/E)XK nuclease family transposase 14 232 1.9E-21 T 21-04-2016 HSISS4_RS02815 54a45010d27d48d07977a4f15b6c3df8 227 Pfam PF09335 SNARE associated Golgi protein 73 185 1.5E-16 T 21-04-2016 IPR032816 SNARE associated Golgi protein HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 PANTHER PTHR33308:SF3 64 218 2.6E-22 T 21-04-2016 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 Pfam PF01832 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase 81 212 1.4E-20 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 PRINTS PR01002 Flagellar protein FlgJ signature 108 129 6.3E-6 T 21-04-2016 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 PRINTS PR01002 Flagellar protein FlgJ signature 193 211 6.3E-6 T 21-04-2016 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 PRINTS PR01002 Flagellar protein FlgJ signature 151 172 6.3E-6 T 21-04-2016 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 SMART SM00047 61 216 7.3E-37 T 21-04-2016 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain GO:0004040 HSISS4_RS02340 4f7d88223dc03fcf285c465d687fadba 218 PANTHER PTHR33308 64 218 2.6E-22 T 21-04-2016 HSISS4_RS07095 0fc57dea0cdc07e6d38e3ca210393ed9 513 Pfam PF09913 Predicted membrane protein (DUF2142) 81 458 9.2E-67 T 21-04-2016 IPR018674 Protein of unknown function DUF2142, membrane HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 PIRSF PIRSF002144 1 92 3.8E-32 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.494 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.1E-47 T 21-04-2016 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 Gene3D G3DSA:3.30.860.10 1 92 1.1E-41 T 21-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 Pfam PF00203 Ribosomal protein S19 3 83 1.2E-37 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-23 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-23 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-23 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 SUPERFAMILY SSF54570 3 84 6.02E-35 T 21-04-2016 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 21-04-2016 IPR020934 Ribosomal protein S19 conserved site GO:0003723 HSISS4_RS09330 0e626640b55ead65d5a65bcf781031d5 92 PANTHER PTHR11880 1 91 1.8E-54 T 21-04-2016 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 HSISS4_RS01495 ed2569339a30cc966e8ad7e4c17b236e 304 Pfam PF03613 PTS system mannose/fructose/sorbose family IID component 7 304 5.1E-112 T 21-04-2016 IPR004704 Phosphotransferase system, mannose/fructose/sorbose family IID component GO:0009401|GO:0016021 HSISS4_RS01495 ed2569339a30cc966e8ad7e4c17b236e 304 PANTHER PTHR32502:SF5 1 304 3.9E-150 T 21-04-2016 HSISS4_RS01495 ed2569339a30cc966e8ad7e4c17b236e 304 TIGRFAM TIGR00828 EIID-AGA: PTS system, mannose/fructose/sorbose family, IID component 7 219 3.7E-89 T 21-04-2016 IPR018405 Phosphotransferase system, mannose/fructose/sorbose family IID component, subgroup GO:0009401|GO:0016021 HSISS4_RS01495 ed2569339a30cc966e8ad7e4c17b236e 304 PANTHER PTHR32502 1 304 3.9E-150 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 255 2.3E-55 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 PANTHER PTHR30614 29 269 2.5E-64 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 SMART SM00062 38 260 1.2E-53 T 21-04-2016 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 SMART SM00079 38 256 6.9E-4 T 21-04-2016 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 Gene3D G3DSA:3.40.190.10 223 258 3.3E-38 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 Gene3D G3DSA:3.40.190.10 35 118 3.3E-38 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 PANTHER PTHR30614:SF15 29 269 2.5E-64 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 Gene3D G3DSA:3.40.190.10 119 218 1.9E-21 T 21-04-2016 HSISS4_RS07175 dfce6a4d89160f597a1bc79b95f25ba9 270 SUPERFAMILY SSF53850 4 256 7.98E-64 T 21-04-2016 HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 PANTHER PTHR33498 1 414 9.9E-107 T 21-04-2016 HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 92 141 6.8E-13 T 21-04-2016 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 SUPERFAMILY SSF46689 102 142 8.07E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 Gene3D G3DSA:1.10.10.60 106 139 1.3E-6 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 Pfam PF01610 Transposase 157 400 4.7E-47 T 21-04-2016 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 41 85 2.5E-10 T 21-04-2016 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger HSISS4_RS06345 fce3c31268224f8ef617994f488338bd 418 PANTHER PTHR33498:SF1 1 414 9.9E-107 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 SUPERFAMILY SSF82549 10 329 5.23E-122 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 PANTHER PTHR28629 1 329 6.7E-161 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 Gene3D G3DSA:3.30.1180.20 184 329 2.0E-51 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 Pfam PF02733 Dak1 domain 18 327 4.4E-117 T 21-04-2016 IPR004006 DhaK domain GO:0004371|GO:0006071 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 Gene3D G3DSA:3.40.50.10440 11 181 4.5E-73 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 PANTHER PTHR28629:SF2 1 329 6.7E-161 T 21-04-2016 HSISS4_RS06465 f4392740ae513430ff233f5cd95ccb98 329 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 1.1E-150 T 21-04-2016 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 KEGG: 00563+2.7.-.-|UniPathway: UPA00616 HSISS4_RS07625 99400817995fa7dca97a9307575b29a4 67 SUPERFAMILY SSF55008 1 62 1.44E-15 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS07625 99400817995fa7dca97a9307575b29a4 67 Pfam PF00403 Heavy-metal-associated domain 4 61 3.6E-15 T 21-04-2016 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 HSISS4_RS07625 99400817995fa7dca97a9307575b29a4 67 Gene3D G3DSA:3.30.70.100 1 62 1.6E-18 T 21-04-2016 HSISS4_RS07625 99400817995fa7dca97a9307575b29a4 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 21-04-2016 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 HSISS4_RS06710 7a2b04ac57cbc34a9e4a9e9efa2210bc 180 Pfam PF06458 MucBP domain 7 40 0.025 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06710 7a2b04ac57cbc34a9e4a9e9efa2210bc 180 Pfam PF06458 MucBP domain 51 139 3.5E-11 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06710 7a2b04ac57cbc34a9e4a9e9efa2210bc 180 Pfam PF06458 MucBP domain 150 172 0.011 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06710 7a2b04ac57cbc34a9e4a9e9efa2210bc 180 Gene3D G3DSA:3.10.20.320 47 141 6.5E-9 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06710 7a2b04ac57cbc34a9e4a9e9efa2210bc 180 Gene3D G3DSA:3.10.20.320 146 169 7.5E-4 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS03055 7146490f89a7b1d3e6fc92b4b3cd8956 473 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 214 391 2.1E-49 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS03055 7146490f89a7b1d3e6fc92b4b3cd8956 473 PANTHER PTHR33392:SF6 74 469 7.5E-79 T 21-04-2016 HSISS4_RS03055 7146490f89a7b1d3e6fc92b4b3cd8956 473 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 213 390 1.3E-24 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS03055 7146490f89a7b1d3e6fc92b4b3cd8956 473 PANTHER PTHR33392 74 469 7.5E-79 T 21-04-2016 HSISS4_RS09495 7446097bf82bb001771a70534656129d 223 PANTHER PTHR33408 1 157 4.7E-12 T 21-04-2016 HSISS4_RS09495 7446097bf82bb001771a70534656129d 223 Pfam PF05598 Transposase domain (DUF772) 54 128 1.0E-19 T 21-04-2016 IPR008490 Transposase InsH, N-terminal HSISS4_RS09495 7446097bf82bb001771a70534656129d 223 PANTHER PTHR33408:SF2 1 157 4.7E-12 T 21-04-2016 HSISS4_RS04575 7256aeb83c73cc74f4ceed4933a502f0 237 PANTHER PTHR11922 36 197 1.1E-35 T 21-04-2016 HSISS4_RS04575 7256aeb83c73cc74f4ceed4933a502f0 237 PANTHER PTHR11922:SF11 36 197 1.1E-35 T 21-04-2016 HSISS4_RS04575 7256aeb83c73cc74f4ceed4933a502f0 237 Pfam PF00117 Glutamine amidotransferase class-I 31 186 1.1E-13 T 21-04-2016 IPR017926 Glutamine amidotransferase Reactome: REACT_1698 HSISS4_RS04575 7256aeb83c73cc74f4ceed4933a502f0 237 Gene3D G3DSA:3.40.50.880 1 227 3.9E-48 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS04575 7256aeb83c73cc74f4ceed4933a502f0 237 SUPERFAMILY SSF52317 1 197 2.75E-34 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05225 fd3752ae43403c68ecb81edc3fcf216f 264 PANTHER PTHR33514 22 264 1.2E-28 T 21-04-2016 HSISS4_RS05225 fd3752ae43403c68ecb81edc3fcf216f 264 Pfam PF02361 Cobalt transport protein 17 225 4.2E-23 T 21-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HSISS4_RS08515 bcdf39be98f0b7a41b1cbaf618bd762e 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 105 3.1E-23 T 21-04-2016 IPR008407 Branched-chain amino acid transport, AzlD HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 SUPERFAMILY SSF56784 3 277 5.52E-64 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 246 2.3E-23 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 PIRSF PIRSF037492 1 461 1.0E-266 T 21-04-2016 IPR017223 Predicted hydrolase of the HAD superfamily, SPs0319-type HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 PANTHER PTHR10000 4 279 1.6E-88 T 21-04-2016 HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 297 410 5.0E-26 T 21-04-2016 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31|UniPathway: UPA00031 HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 PANTHER PTHR10000:SF25 4 279 1.6E-88 T 21-04-2016 HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 ProSitePatterns PS01229 Hypothetical cof family signature 2. 227 249 - T 21-04-2016 HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 273 6.1E-66 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 Gene3D G3DSA:1.10.3420.10 289 455 2.1E-55 T 21-04-2016 IPR023292 NTP pyrophosphohydrolase-like domain HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 Gene3D G3DSA:3.40.50.1000 3 72 1.1E-54 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 Gene3D G3DSA:3.40.50.1000 182 279 1.1E-54 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS08280 9a37d094274b68591b2b45e9d75f797d 461 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 273 1.7E-52 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 96 21.908 T 21-04-2016 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 PANTHER PTHR21011 1 95 3.5E-26 T 21-04-2016 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 SUPERFAMILY SSF54995 1 95 1.7E-32 T 21-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 Gene3D G3DSA:3.30.70.60 1 95 2.7E-34 T 21-04-2016 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 Pfam PF01250 Ribosomal protein S6 3 93 5.4E-27 T 21-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS08450 57020c872e91ff3cf2cf35be584094f9 96 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 95 7.4E-26 T 21-04-2016 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 SUPERFAMILY SSF48498 78 169 7.11E-11 T 21-04-2016 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 PANTHER PTHR30055:SF90 1 109 1.0E-12 T 21-04-2016 HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 Gene3D G3DSA:1.10.357.10 9 179 1.3E-23 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.9E-7 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 SUPERFAMILY SSF46689 4 76 1.08E-9 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 Pfam PF13305 WHG domain 81 164 5.3E-13 T 21-04-2016 IPR025996 WHG domain HSISS4_RS06260 f1f32dfbfcec2cc74405946c50819d9a 191 PANTHER PTHR30055 1 109 1.0E-12 T 21-04-2016 HSISS4_RS08830 0e1712fcb8c813db4a142c31f79aa15a 435 Gene3D G3DSA:3.30.565.10 308 412 4.7E-6 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS08830 0e1712fcb8c813db4a142c31f79aa15a 435 PANTHER PTHR40448 72 435 2.7E-50 T 21-04-2016 HSISS4_RS08830 0e1712fcb8c813db4a142c31f79aa15a 435 PANTHER PTHR40448:SF1 72 435 2.7E-50 T 21-04-2016 HSISS4_RS08830 0e1712fcb8c813db4a142c31f79aa15a 435 SUPERFAMILY SSF55874 299 412 2.41E-8 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS08830 0e1712fcb8c813db4a142c31f79aa15a 435 Pfam PF14501 GHKL domain 330 431 5.1E-14 T 21-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain HSISS4_RS00035 87d1dedbec61ebea04d9f04fa61cffd9 91 Gene3D G3DSA:3.10.290.10 2 89 5.0E-24 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS00035 87d1dedbec61ebea04d9f04fa61cffd9 91 SUPERFAMILY SSF55174 2 78 4.45E-20 T 21-04-2016 HSISS4_RS00035 87d1dedbec61ebea04d9f04fa61cffd9 91 PIRSF PIRSF038881 1 89 6.7E-39 T 21-04-2016 IPR025490 RNA-binding protein, HP1423 type HSISS4_RS00035 87d1dedbec61ebea04d9f04fa61cffd9 91 SMART SM00363 1 62 4.9E-7 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS00035 87d1dedbec61ebea04d9f04fa61cffd9 91 Pfam PF01479 S4 domain 1 47 7.1E-9 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 SMART SM00382 32 223 1.8E-10 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 PANTHER PTHR24220 4 246 1.4E-94 T 21-04-2016 HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 PANTHER PTHR24220:SF66 4 246 1.4E-94 T 21-04-2016 HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 Gene3D G3DSA:3.40.50.300 3 235 1.2E-65 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 SUPERFAMILY SSF52540 1 236 2.03E-57 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 277 3.6E-120 T 21-04-2016 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 HSISS4_RS09650 577f554eb1c3998d925fe5119202a8ef 280 Pfam PF00005 ABC transporter 25 174 3.7E-31 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04515 ce756396589e4be20cb3a1d258aca54c 157 SUPERFAMILY SSF55729 1 151 3.77E-28 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04515 ce756396589e4be20cb3a1d258aca54c 157 Pfam PF00583 Acetyltransferase (GNAT) family 73 146 7.8E-15 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS04515 ce756396589e4be20cb3a1d258aca54c 157 Gene3D G3DSA:3.40.630.30 1 156 1.4E-35 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS04515 ce756396589e4be20cb3a1d258aca54c 157 PANTHER PTHR23091 1 147 5.5E-22 T 21-04-2016 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 279 2.2E-58 T 21-04-2016 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 PANTHER PTHR11079 40 276 2.0E-55 T 21-04-2016 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 126 140 - T 21-04-2016 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 SUPERFAMILY SSF55120 83 278 5.6E-60 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 Pfam PF00849 RNA pseudouridylate synthase 89 235 2.3E-31 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS01005 f499b84c49b173986581398f4f45ae11 290 PANTHER PTHR11079:SF91 40 276 2.0E-55 T 21-04-2016 HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 SMART SM00382 27 203 4.0E-14 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 PANTHER PTHR24220 242 273 4.7E-80 T 21-04-2016 HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 PANTHER PTHR24220 4 212 4.7E-80 T 21-04-2016 HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 Pfam PF00005 ABC transporter 18 148 6.9E-32 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 SUPERFAMILY SSF52540 2 210 5.82E-64 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 Gene3D G3DSA:3.40.50.300 2 215 5.0E-68 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS01055 a73c6b2e6a031df17d862731574a06c7 288 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Gene3D G3DSA:3.30.930.10 2 205 6.6E-86 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Gene3D G3DSA:3.30.930.10 268 279 6.6E-86 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Gene3D G3DSA:3.30.930.10 436 489 6.6E-86 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 SUPERFAMILY SSF55681 4 224 1.84E-83 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 SUPERFAMILY SSF55681 436 519 1.84E-83 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 611 37.511 T 21-04-2016 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Gene3D G3DSA:3.90.960.10 280 417 1.2E-34 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451:SF3 250 277 1.3E-128 T 21-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451:SF3 1 211 1.3E-128 T 21-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451:SF3 428 609 1.3E-128 T 21-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Pfam PF04073 Aminoacyl-tRNA editing domain 290 407 1.0E-25 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PRINTS PR01046 Prolyl-tRNA synthetase signature 63 81 4.7E-15 T 21-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PRINTS PR01046 Prolyl-tRNA synthetase signature 129 137 4.7E-15 T 21-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PRINTS PR01046 Prolyl-tRNA synthetase signature 139 150 4.7E-15 T 21-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PRINTS PR01046 Prolyl-tRNA synthetase signature 99 110 4.7E-15 T 21-04-2016 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Gene3D G3DSA:3.40.50.800 509 612 1.6E-24 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 SUPERFAMILY SSF52954 506 607 3.44E-25 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 89 488 3.2E-58 T 21-04-2016 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 Reactome: REACT_71 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 Pfam PF03129 Anticodon binding domain 517 606 8.4E-16 T 21-04-2016 IPR004154 Anticodon-binding HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 242 606 4.2E-96 T 21-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 209 1.4E-93 T 21-04-2016 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451 250 277 1.3E-128 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451 1 211 1.3E-128 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 PANTHER PTHR11451 428 609 1.3E-128 T 21-04-2016 HSISS4_RS00970 ea93cae9ba20fbe344eb0a6f52fd4579 615 SUPERFAMILY SSF55826 251 418 7.46E-34 T 21-04-2016 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 SUPERFAMILY SSF53850 33 598 1.72E-78 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290 330 388 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290 1 311 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290 404 628 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 Gene3D G3DSA:3.40.190.10 209 340 4.0E-16 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 521 2.8E-45 T 21-04-2016 IPR000914 Solute-binding protein family 5 domain HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 80 102 - T 21-04-2016 IPR023765 Solute-binding protein family 5, conserved site HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290:SF10 330 388 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290:SF10 1 311 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 PANTHER PTHR30290:SF10 404 628 9.6E-131 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 Gene3D G3DSA:3.10.105.10 341 583 3.0E-32 T 21-04-2016 HSISS4_RS08840 e9dd0935c00f5976464a9afd01690b43 656 Gene3D G3DSA:3.90.76.10 41 208 4.7E-38 T 21-04-2016 HSISS4_RS01340 4dd429cd7c2a3a9afc7971512e9b16f3 279 PANTHER PTHR33643 7 274 1.0E-32 T 21-04-2016 HSISS4_RS01340 4dd429cd7c2a3a9afc7971512e9b16f3 279 Hamap MF_01384 Urease accessory protein UreD [ureD]. 5 261 20.912 T 21-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 HSISS4_RS01340 4dd429cd7c2a3a9afc7971512e9b16f3 279 Pfam PF01774 UreD urease accessory protein 47 250 2.1E-39 T 21-04-2016 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 HSISS4_RS01340 4dd429cd7c2a3a9afc7971512e9b16f3 279 PANTHER PTHR33643:SF1 7 274 1.0E-32 T 21-04-2016 HSISS4_RS07135 323c22e504c68a28ddf5f481af0e6868 111 SUPERFAMILY SSF117916 14 109 5.23E-31 T 21-04-2016 HSISS4_RS07135 323c22e504c68a28ddf5f481af0e6868 111 Pfam PF01883 Domain of unknown function DUF59 15 88 2.0E-22 T 21-04-2016 IPR002744 Domain of unknown function DUF59 HSISS4_RS07135 323c22e504c68a28ddf5f481af0e6868 111 PANTHER PTHR13696:SF62 3 108 4.2E-22 T 21-04-2016 HSISS4_RS07135 323c22e504c68a28ddf5f481af0e6868 111 PANTHER PTHR13696 3 108 4.2E-22 T 21-04-2016 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 PANTHER PTHR15004:SF0 1 96 2.4E-32 T 21-04-2016 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 PANTHER PTHR15004 1 96 2.4E-32 T 21-04-2016 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 3 95 2.3E-29 T 21-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 24.622 T 21-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 19 90 1.6E-18 T 21-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HSISS4_RS07875 217054a46f569eb493d1fbe49fb39d63 100 SUPERFAMILY SSF141000 2 93 8.63E-27 T 21-04-2016 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 SUPERFAMILY SSF55347 130 293 3.76E-35 T 21-04-2016 HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 PANTHER PTHR22604 8 326 1.1E-61 T 21-04-2016 HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 Gene3D G3DSA:3.30.360.10 147 326 7.3E-44 T 21-04-2016 HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 Gene3D G3DSA:3.40.50.720 6 146 6.2E-40 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 SUPERFAMILY SSF51735 7 157 9.09E-42 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 PANTHER PTHR22604:SF105 8 326 1.1E-61 T 21-04-2016 HSISS4_RS06450 9af7775b07d297341685ee42a149e730 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 122 8.6E-20 T 21-04-2016 IPR000683 Oxidoreductase, N-terminal GO:0016491 HSISS4_RS01015 8166a74ed830a9293cf100b06e5bf5f1 58 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 8 54 1.4E-9 T 21-04-2016 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 HSISS4_RS01015 8166a74ed830a9293cf100b06e5bf5f1 58 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 11 54 7.8E-9 T 21-04-2016 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 HSISS4_RS01015 8166a74ed830a9293cf100b06e5bf5f1 58 Gene3D G3DSA:1.20.5.1030 11 55 1.4E-10 T 21-04-2016 HSISS4_RS03345 e8f08dcd18c4ee1cc6b97c43b9b5e95b 146 Pfam PF12732 YtxH-like protein 7 96 1.8E-9 T 21-04-2016 IPR024623 Uncharacterised protein family YtxH HSISS4_RS05975 bfd8c269bb31fdaee9c4dcb8e1b2c1d4 107 PRINTS PR00169 Potassium channel signature 41 63 2.6E-5 T 21-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HSISS4_RS05975 bfd8c269bb31fdaee9c4dcb8e1b2c1d4 107 PRINTS PR00169 Potassium channel signature 70 96 2.6E-5 T 21-04-2016 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 HSISS4_RS05975 bfd8c269bb31fdaee9c4dcb8e1b2c1d4 107 Pfam PF07885 Ion channel 24 97 2.1E-13 T 21-04-2016 IPR013099 Potassium channel domain HSISS4_RS05975 bfd8c269bb31fdaee9c4dcb8e1b2c1d4 107 Gene3D G3DSA:1.10.287.70 19 103 3.3E-18 T 21-04-2016 HSISS4_RS05975 bfd8c269bb31fdaee9c4dcb8e1b2c1d4 107 SUPERFAMILY SSF81324 16 99 2.22E-18 T 21-04-2016 HSISS4_RS07080 c260b5f9a79f86002a6488c406d37ec8 269 PANTHER PTHR30413:SF8 7 269 9.6E-49 T 21-04-2016 HSISS4_RS07080 c260b5f9a79f86002a6488c406d37ec8 269 Pfam PF01061 ABC-2 type transporter 13 219 2.8E-18 T 21-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HSISS4_RS07080 c260b5f9a79f86002a6488c406d37ec8 269 PANTHER PTHR30413 7 269 9.6E-49 T 21-04-2016 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 HSISS4_RS09450 d465664a2e386ccc318a5236d6ac0961 313 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 251 306 1.4E-15 T 21-04-2016 IPR019264 Domain of unknown function DUF2179 HSISS4_RS09450 d465664a2e386ccc318a5236d6ac0961 313 PANTHER PTHR33545:SF5 21 310 1.5E-111 T 21-04-2016 HSISS4_RS09450 d465664a2e386ccc318a5236d6ac0961 313 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 43 245 1.4E-56 T 21-04-2016 IPR003740 Uncharacterised membrane protein YitT HSISS4_RS09450 d465664a2e386ccc318a5236d6ac0961 313 PANTHER PTHR33545 21 310 1.5E-111 T 21-04-2016 HSISS4_RS09450 d465664a2e386ccc318a5236d6ac0961 313 PIRSF PIRSF006483 19 313 3.0E-100 T 21-04-2016 IPR003740 Uncharacterised membrane protein YitT HSISS4_RS06485 4f9ad2353296ae9e56fc72de312890d5 201 Pfam PF07853 Protein of unknown function (DUF1648) 12 60 2.3E-14 T 21-04-2016 IPR012867 Domain of unknown function DUF1648 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 Pfam PF07687 Peptidase dimerisation domain 199 356 1.3E-16 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 PANTHER PTHR11014:SF15 289 456 2.0E-109 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 PANTHER PTHR11014:SF15 1 269 2.0E-109 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 SUPERFAMILY SSF53187 371 456 1.0E-47 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 SUPERFAMILY SSF53187 16 201 1.0E-47 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 Gene3D G3DSA:3.30.70.360 212 369 1.6E-51 T 21-04-2016 IPR011650 Peptidase M20, dimerisation domain HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 PANTHER PTHR11014 289 456 2.0E-109 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 PANTHER PTHR11014 1 269 2.0E-109 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 Pfam PF01546 Peptidase family M20/M25/M40 86 454 8.3E-34 T 21-04-2016 IPR002933 Peptidase M20 GO:0008152|GO:0016787 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 Gene3D G3DSA:3.40.630.10 20 211 3.8E-51 T 21-04-2016 HSISS4_RS01370 29c90217ca2d777c209b1353c820868d 457 Gene3D G3DSA:3.40.630.10 396 456 3.8E-51 T 21-04-2016 HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 PANTHER PTHR40448:SF1 1 439 2.3E-57 T 21-04-2016 HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 Gene3D G3DSA:3.30.565.10 300 415 1.2E-5 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 Pfam PF14501 GHKL domain 333 435 4.4E-14 T 21-04-2016 IPR032834 Sensor histidine kinase NatK, C-terminal domain HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 PANTHER PTHR40448 1 439 2.3E-57 T 21-04-2016 HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 Gene3D G3DSA:1.10.287.130 222 261 7.8E-5 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS02140 e1619b9afd044088b14cd13b1c521f51 439 SUPERFAMILY SSF55874 300 415 1.46E-7 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06195 f15119fe847d4d85298dba77fde36774 442 Pfam PF05525 Branched-chain amino acid transport protein 7 431 8.5E-139 T 21-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HSISS4_RS06195 f15119fe847d4d85298dba77fde36774 442 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 11 419 9.6E-112 T 21-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HSISS4_RS06195 f15119fe847d4d85298dba77fde36774 442 PANTHER PTHR30588 1 442 4.0E-210 T 21-04-2016 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 HSISS4_RS06195 f15119fe847d4d85298dba77fde36774 442 PANTHER PTHR30588:SF2 1 442 4.0E-210 T 21-04-2016 HSISS4_RS05250 6b9c1be330c280d77987f66d2c308d05 887 Pfam PF02687 FtsX-like permease family 761 863 5.1E-15 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS05250 6b9c1be330c280d77987f66d2c308d05 887 Pfam PF02687 FtsX-like permease family 356 471 8.7E-13 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS05250 6b9c1be330c280d77987f66d2c308d05 887 PANTHER PTHR30287 329 887 5.8E-54 T 21-04-2016 HSISS4_RS05250 6b9c1be330c280d77987f66d2c308d05 887 PANTHER PTHR30287 1 229 5.8E-54 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 176 255 2.0E-24 T 21-04-2016 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 296 653 2.0E-113 T 21-04-2016 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 PANTHER PTHR30505:SF0 411 649 1.6E-264 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 PANTHER PTHR30505:SF0 43 391 1.6E-264 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 Pfam PF02378 Phosphotransferase system, EIIC 303 600 2.0E-20 T 21-04-2016 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 PANTHER PTHR30505 411 649 1.6E-264 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 PANTHER PTHR30505 43 391 1.6E-264 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 1.6E-35 T 21-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 Gene3D G3DSA:3.40.930.10 1 152 2.5E-51 T 21-04-2016 IPR002178 PTS EIIA type-2 domain KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 177 266 9.7E-13 T 21-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 SUPERFAMILY SSF55804 1 147 2.62E-42 T 21-04-2016 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: REACT_15518 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 SUPERFAMILY SSF52794 175 274 7.15E-32 T 21-04-2016 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 Gene3D G3DSA:3.40.50.2300 170 275 7.6E-39 T 21-04-2016 HSISS4_RS01865 7997cc575988380711c81be72511ba7b 658 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 7.3E-43 T 21-04-2016 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS02740 282b2b6eae78b6bc724b4caad0d5114d 316 Pfam PF02574 Homocysteine S-methyltransferase 14 312 9.2E-69 T 21-04-2016 IPR003726 Homocysteine-binding domain HSISS4_RS02740 282b2b6eae78b6bc724b4caad0d5114d 316 SUPERFAMILY SSF82282 3 315 2.22E-78 T 21-04-2016 IPR003726 Homocysteine-binding domain HSISS4_RS02740 282b2b6eae78b6bc724b4caad0d5114d 316 PANTHER PTHR21091:SF123 1 310 2.8E-85 T 21-04-2016 HSISS4_RS02740 282b2b6eae78b6bc724b4caad0d5114d 316 Gene3D G3DSA:3.20.20.330 4 314 5.9E-87 T 21-04-2016 IPR003726 Homocysteine-binding domain HSISS4_RS02740 282b2b6eae78b6bc724b4caad0d5114d 316 PANTHER PTHR21091 1 310 2.8E-85 T 21-04-2016 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 Pfam PF00425 chorismate binding enzyme 187 440 3.3E-92 T 21-04-2016 IPR015890 Chorismate-utilising enzyme, C-terminal HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 SUPERFAMILY SSF56322 4 446 1.13E-145 T 21-04-2016 IPR005801 ADC synthase GO:0009058 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PANTHER PTHR11236 1 446 2.4E-206 T 21-04-2016 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 7 447 4.5E-173 T 21-04-2016 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PANTHER PTHR11236:SF9 1 446 2.4E-206 T 21-04-2016 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PRINTS PR00095 Anthranilate synthase component I signature 288 301 9.1E-22 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PRINTS PR00095 Anthranilate synthase component I signature 397 411 9.1E-22 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PRINTS PR00095 Anthranilate synthase component I signature 382 396 9.1E-22 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 PRINTS PR00095 Anthranilate synthase component I signature 302 315 9.1E-22 T 21-04-2016 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 Gene3D G3DSA:3.60.120.10 4 447 2.4E-151 T 21-04-2016 IPR005801 ADC synthase GO:0009058 HSISS4_RS07675 8251e9e04243a4b4f30106973ab36ffe 451 Pfam PF04715 Anthranilate synthase component I, N terminal region 8 138 3.3E-29 T 21-04-2016 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058|GO:0016833 KEGG: 00400+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661|UniPathway: UPA00035 HSISS4_RS06285 e82a8971cd58a0c01651de815a859cd0 200 PANTHER PTHR23026:SF89 1 197 1.2E-67 T 21-04-2016 HSISS4_RS06285 e82a8971cd58a0c01651de815a859cd0 200 Gene3D G3DSA:3.40.109.10 3 197 2.3E-61 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS06285 e82a8971cd58a0c01651de815a859cd0 200 Pfam PF00881 Nitroreductase family 10 177 9.2E-12 T 21-04-2016 IPR029479 Nitroreductase HSISS4_RS06285 e82a8971cd58a0c01651de815a859cd0 200 PANTHER PTHR23026 1 197 1.2E-67 T 21-04-2016 HSISS4_RS06285 e82a8971cd58a0c01651de815a859cd0 200 SUPERFAMILY SSF55469 3 198 2.75E-64 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 24 210 29.849 T 21-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 Gene3D G3DSA:3.40.50.620 23 209 3.0E-62 T 21-04-2016 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 87 1.2E-7 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 28 209 2.5E-50 T 21-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 PANTHER PTHR12039 3 210 1.6E-48 T 21-04-2016 IPR005248 Probable nicotinate-nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|Reactome: REACT_11193|UniPathway: UPA00253 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 Pfam PF01467 Cytidylyltransferase-like 28 183 1.7E-32 T 21-04-2016 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 HSISS4_RS07825 3243b453c04c2280ca5df409d9eb8b89 210 SUPERFAMILY SSF52374 23 209 7.51E-49 T 21-04-2016 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 Gene3D G3DSA:3.40.192.10 2 111 4.7E-41 T 21-04-2016 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 9 275 2.2E-70 T 21-04-2016 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 PANTHER PTHR21089 1 277 2.0E-90 T 21-04-2016 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 SUPERFAMILY SSF51735 107 283 3.13E-34 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 SUPERFAMILY SSF53223 1 106 2.19E-34 T 21-04-2016 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 7 281 33.909 T 21-04-2016 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 12 94 1.6E-27 T 21-04-2016 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163|UniPathway: UPA00053 HSISS4_RS03010 b72e125642b3ec0d4415242003537240 285 Gene3D G3DSA:3.40.50.720 112 283 3.1E-45 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 Gene3D G3DSA:3.30.428.10 3 120 7.7E-43 T 21-04-2016 IPR011146 HIT-like domain GO:0003824 HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 SUPERFAMILY SSF54197 2 128 9.43E-44 T 21-04-2016 IPR011146 HIT-like domain GO:0003824 HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 PANTHER PTHR23089:SF14 1 120 2.5E-69 T 21-04-2016 HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 PANTHER PTHR23089 1 120 2.5E-69 T 21-04-2016 IPR001310 Histidine triad (HIT) protein HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 Pfam PF01230 HIT domain 12 106 4.3E-27 T 21-04-2016 IPR001310 Histidine triad (HIT) protein HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 PRINTS PR00332 Histidine triad family signature 5 21 3.3E-18 T 21-04-2016 IPR001310 Histidine triad (HIT) protein HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 PRINTS PR00332 Histidine triad family signature 93 103 3.3E-18 T 21-04-2016 IPR001310 Histidine triad (HIT) protein HSISS4_RS07775 9dc0e1d10f0e9fe022c68353050d8b12 139 PRINTS PR00332 Histidine triad family signature 26 44 3.3E-18 T 21-04-2016 IPR001310 Histidine triad (HIT) protein HSISS4_RS06630 19e4581a1c9584482d256b5647b9a13c 116 SUPERFAMILY SSF47413 7 72 8.16E-14 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS06630 19e4581a1c9584482d256b5647b9a13c 116 Pfam PF01381 Helix-turn-helix 16 69 1.0E-9 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06630 19e4581a1c9584482d256b5647b9a13c 116 SMART SM00530 14 69 5.2E-9 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS06630 19e4581a1c9584482d256b5647b9a13c 116 Gene3D G3DSA:1.10.260.40 11 110 1.5E-17 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 PANTHER PTHR11119 1 163 9.2E-134 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 PANTHER PTHR11119 193 459 9.2E-134 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 Pfam PF00860 Permease family 170 432 7.3E-26 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 Pfam PF00860 Permease family 17 161 3.3E-14 T 21-04-2016 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 PANTHER PTHR11119:SF9 1 163 9.2E-134 T 21-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 PANTHER PTHR11119:SF9 193 459 9.2E-134 T 21-04-2016 IPR029940 AzgA purine transporter GO:0005345|GO:0006863 HSISS4_RS01520 7a31a27e92599407b3376e4cb54bde38 473 PIRSF PIRSF005353 1 472 1.4E-157 T 21-04-2016 IPR026033 Purine permease PbuG-like HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 SUPERFAMILY SSF53474 7 277 1.34E-53 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 222 236 1.1E-10 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 1.1E-10 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 1.1E-10 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 1.1E-10 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PANTHER PTHR10992 218 278 5.8E-42 T 21-04-2016 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 PANTHER PTHR10992 7 190 5.8E-42 T 21-04-2016 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 Pfam PF00561 alpha/beta hydrolase fold 38 263 2.7E-20 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS05195 c75daa7b2f26cb0ae5d7d9a1a9fd0c25 278 Gene3D G3DSA:3.40.50.1820 7 277 5.8E-50 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS09435 e3d75130bbd2c2ddb82d803ebbf04ac2 166 Pfam PF13302 Acetyltransferase (GNAT) domain 2 148 8.8E-15 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS09435 e3d75130bbd2c2ddb82d803ebbf04ac2 166 PANTHER PTHR39173 1 166 3.1E-51 T 21-04-2016 HSISS4_RS09435 e3d75130bbd2c2ddb82d803ebbf04ac2 166 Gene3D G3DSA:3.40.630.30 1 160 2.4E-22 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS09435 e3d75130bbd2c2ddb82d803ebbf04ac2 166 SUPERFAMILY SSF55729 2 157 7.33E-21 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 109 2.6E-51 T 21-04-2016 IPR004624 PhnA protein HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 Pfam PF08274 PhnA Zinc-Ribbon 2 31 5.7E-16 T 21-04-2016 IPR013987 PhnA protein, N-terminal HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 Pfam PF03831 PhnA domain 43 110 1.3E-33 T 21-04-2016 IPR013988 PhnA protein, C-terminal HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 PANTHER PTHR30305 1 110 5.7E-81 T 21-04-2016 HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 SUPERFAMILY SSF57783 1 37 3.4E-15 T 21-04-2016 HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 Gene3D G3DSA:2.20.25.10 1 39 1.4E-22 T 21-04-2016 HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 Gene3D G3DSA:2.30.30.40 41 110 2.0E-37 T 21-04-2016 HSISS4_RS05480 c84433e0c497c62dc92da61f24f8d438 110 SUPERFAMILY SSF82057 38 110 3.02E-28 T 21-04-2016 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 PANTHER PTHR22769 9 144 2.8E-19 T 21-04-2016 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 PRINTS PR00502 NUDIX hydrolase family signature 42 56 8.71E-5 T 21-04-2016 IPR020476 NUDIX hydrolase HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 PRINTS PR00502 NUDIX hydrolase family signature 56 71 8.71E-5 T 21-04-2016 IPR020476 NUDIX hydrolase HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 Pfam PF00293 NUDIX domain 19 133 2.2E-15 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 Gene3D G3DSA:3.90.79.10 2 144 4.3E-44 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 21-04-2016 IPR020084 NUDIX hydrolase, conserved site GO:0016787 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 PANTHER PTHR22769:SF35 9 144 2.8E-19 T 21-04-2016 HSISS4_RS02835 3c04b543cd8d282a30e015d954dfb521 152 SUPERFAMILY SSF55811 6 144 2.3E-29 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 SUPERFAMILY SSF52540 144 188 5.23E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 SUPERFAMILY SSF52540 26 114 5.23E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 SUPERFAMILY SSF52540 427 558 5.23E-24 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 Gene3D G3DSA:3.40.50.300 502 555 9.4E-5 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 Gene3D G3DSA:3.40.50.300 7 204 1.5E-21 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 Pfam PF04851 Type III restriction enzyme, res subunit 10 186 9.2E-20 T 21-04-2016 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 HSISS4_RS05115 a639909eb3f823f5345e1d61b97902b9 904 SMART SM00487 7 217 3.2E-17 T 21-04-2016 IPR014001 Helicase superfamily 1/2, ATP-binding domain HSISS4_RS05520 2a802ca6ef6337477a38bee48e7dc48a 273 Pfam PF13367 Protease prsW family 69 251 1.2E-25 T 21-04-2016 IPR026898 Protease PrsW GO:0008233 KEGG: 00261+3.4.-.-|KEGG: 00310+3.4.-.-|KEGG: 00550+3.4.-.-|KEGG: 00780+3.4.-.- HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 3 167 1.0E-53 T 21-04-2016 IPR006287 DJ-1 HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 PANTHER PTHR11019:SF4 1 164 4.1E-57 T 21-04-2016 HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 SUPERFAMILY SSF52317 1 173 1.54E-50 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 Gene3D G3DSA:3.40.50.880 1 178 2.7E-58 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 Pfam PF01965 DJ-1/PfpI family 3 162 1.1E-44 T 21-04-2016 IPR002818 DJ-1/PfpI HSISS4_RS05075 ad9b3ab4bc7c7cfbee26ed3fead470c3 182 PANTHER PTHR11019 1 164 4.1E-57 T 21-04-2016 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 71 96 - T 21-04-2016 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 Pfam PF13347 MFS/sugar transport protein 13 453 4.4E-84 T 21-04-2016 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 TIGRFAM TIGR00792 gph: sugar (Glycoside-Pentoside-Hexuronide) transporter 11 467 1.2E-160 T 21-04-2016 IPR001927 Sodium:galactoside symporter GO:0005215|GO:0006814|GO:0016020 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 SUPERFAMILY SSF103473 23 459 2.53E-27 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 483 607 2.2E-44 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 484 604 1.9E-44 T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 Gene3D G3DSA:1.20.1250.20 17 228 4.3E-6 T 21-04-2016 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 Gene3D G3DSA:1.20.1250.20 234 459 6.3E-10 T 21-04-2016 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 PANTHER PTHR11328 8 492 2.6E-47 T 21-04-2016 HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 SUPERFAMILY SSF51261 470 615 1.92E-48 T 21-04-2016 IPR011055 Duplicated hybrid motif HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 546 558 - T 21-04-2016 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 KEGG: 00520+2.7.1.-|KEGG: 00540+2.7.1.-|KEGG: 00680+2.7.1.-|KEGG: 00900+2.7.1.- HSISS4_RS06365 7f909226045a6b90c4215cd024834569 634 Gene3D G3DSA:2.70.70.10 475 629 2.3E-52 T 21-04-2016 HSISS4_RS04985 b25aa929a1c4fcd0d652000ab78db609 217 SUPERFAMILY SSF161098 13 206 2.09E-46 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04985 b25aa929a1c4fcd0d652000ab78db609 217 PANTHER PTHR30614 1 217 6.5E-83 T 21-04-2016 HSISS4_RS04985 b25aa929a1c4fcd0d652000ab78db609 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.0E-31 T 21-04-2016 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 HSISS4_RS04985 b25aa929a1c4fcd0d652000ab78db609 217 Gene3D G3DSA:1.10.3720.10 13 214 7.8E-50 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04985 b25aa929a1c4fcd0d652000ab78db609 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 4.6E-25 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS09640 d6eaf744e7bff5a94906204523c09a8f 190 SMART SM00257 33 77 6.9E-16 T 21-04-2016 IPR018392 LysM domain HSISS4_RS09640 d6eaf744e7bff5a94906204523c09a8f 190 Pfam PF01476 LysM domain 34 76 7.9E-13 T 21-04-2016 IPR018392 LysM domain HSISS4_RS09640 d6eaf744e7bff5a94906204523c09a8f 190 Gene3D G3DSA:3.10.350.10 31 77 8.5E-19 T 21-04-2016 IPR018392 LysM domain HSISS4_RS09640 d6eaf744e7bff5a94906204523c09a8f 190 SUPERFAMILY SSF54106 31 76 5.75E-11 T 21-04-2016 IPR018392 LysM domain HSISS4_RS03940 99928f571141b9bb200f3dba98887121 259 Pfam PF09359 VTC domain 11 237 2.1E-28 T 21-04-2016 IPR018966 VTC domain HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PANTHER PTHR11806:SF0 1 633 0.0 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 153 162 3.506829E-6 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 3.506829E-6 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 9 623 2.8E-274 T 21-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 9.76849E-5 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 9.76849E-5 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 SMART SM01228 549 620 3.9E-41 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 371 394 - T 21-04-2016 IPR020595 MnmG-related, conserved site HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 PANTHER PTHR11806 1 633 0.0 T 21-04-2016 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 Gene3D G3DSA:3.50.50.60 9 232 6.3E-34 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 7 627 41.487 T 21-04-2016 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 Pfam PF01134 Glucose inhibited division protein A 10 402 7.4E-165 T 21-04-2016 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 276 290 - T 21-04-2016 IPR020595 MnmG-related, conserved site HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 SUPERFAMILY SSF51905 8 68 2.5E-44 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 SUPERFAMILY SSF51905 99 264 2.5E-44 T 21-04-2016 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 HSISS4_RS09615 c4a92230b2356b7da932b01a5ae7afac 633 Pfam PF13932 GidA associated domain 404 619 1.5E-68 T 21-04-2016 IPR026904 GidA associated domain 3 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 442 2.3E-156 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PANTHER PTHR30330 1 447 1.2E-213 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 411 431 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 86 108 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 351 373 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 212 231 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 307 325 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PRINTS PR00175 Sodium/alanine symporter signature 184 202 9.1E-57 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 Pfam PF01235 Sodium:alanine symporter family 50 447 3.3E-148 T 21-04-2016 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 HSISS4_RS04965 7c16d98c47d990a77fd26285695ead21 447 PANTHER PTHR30330:SF3 1 447 1.2E-213 T 21-04-2016 HSISS4_RS03155 a5f1e27dc5d6e6a194638344764466f9 189 PANTHER PTHR30328 3 176 7.2E-19 T 21-04-2016 HSISS4_RS03155 a5f1e27dc5d6e6a194638344764466f9 189 PANTHER PTHR30328:SF20 3 176 7.2E-19 T 21-04-2016 HSISS4_RS03155 a5f1e27dc5d6e6a194638344764466f9 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 74 1.9E-10 T 21-04-2016 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 HSISS4_RS03155 a5f1e27dc5d6e6a194638344764466f9 189 Gene3D G3DSA:1.10.357.10 19 176 2.4E-16 T 21-04-2016 IPR015893 Tetracycline transcriptional regulator, TetR-like, C-terminal GO:0003677 HSISS4_RS03155 a5f1e27dc5d6e6a194638344764466f9 189 SUPERFAMILY SSF46689 20 85 1.28E-13 T 21-04-2016 IPR009057 Homeodomain-like GO:0003677 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 Pfam PF00905 Penicillin binding protein transpeptidase domain 425 693 4.8E-36 T 21-04-2016 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 165 706 2.6E-167 T 21-04-2016 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 Gene3D G3DSA:1.10.3810.10 156 325 1.4E-67 T 21-04-2016 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 PANTHER PTHR32282 82 717 2.1E-191 T 21-04-2016 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 SUPERFAMILY SSF53955 144 345 2.81E-66 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 Gene3D G3DSA:3.40.710.10 326 737 1.6E-100 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 PANTHER PTHR32282:SF5 82 717 2.1E-191 T 21-04-2016 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 Pfam PF00912 Transglycosylase 158 324 1.0E-58 T 21-04-2016 IPR001264 Glycosyl transferase, family 51 UniPathway: UPA00219 HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 SUPERFAMILY SSF56601 306 328 1.66E-100 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS01010 a9729a968e2ddd6dc608dcd7440a1332 775 SUPERFAMILY SSF56601 361 715 1.66E-100 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS00250 954b551d04cf4ae6fc894e28ec402eda 279 SUPERFAMILY SSF54001 26 166 7.94E-28 T 21-04-2016 HSISS4_RS00250 954b551d04cf4ae6fc894e28ec402eda 279 Pfam PF05257 CHAP domain 48 135 2.5E-13 T 21-04-2016 IPR007921 CHAP domain HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 265 5.0E-60 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 PANTHER PTHR10000:SF1 1 271 4.8E-77 T 21-04-2016 HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 265 3.9E-64 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 Gene3D G3DSA:3.40.50.1000 184 270 2.5E-53 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 Gene3D G3DSA:3.40.50.1000 1 77 2.5E-53 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 SUPERFAMILY SSF56784 2 270 5.29E-70 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 237 2.8E-27 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 PANTHER PTHR10000 1 271 4.8E-77 T 21-04-2016 HSISS4_RS06955 fbfab6bfea8e151683cba7f77f3dc8d1 272 Gene3D G3DSA:3.30.1240.10 88 183 2.0E-22 T 21-04-2016 HSISS4_RS03750 c7e8ce3ce88086039f39f7087d5cf6f5 86 PANTHER PTHR37290:SF1 5 73 3.2E-17 T 21-04-2016 HSISS4_RS03750 c7e8ce3ce88086039f39f7087d5cf6f5 86 Pfam PF05360 yiaA/B two helix domain 15 67 1.6E-12 T 21-04-2016 IPR008024 YiaAB two helix HSISS4_RS03750 c7e8ce3ce88086039f39f7087d5cf6f5 86 PANTHER PTHR37290 5 73 3.2E-17 T 21-04-2016 HSISS4_RS04325 96beaee6386b6f31ee648a80bc957ecc 62 ProDom PD053619 EPUA PRECURSOR SIGNAL PEPTIDE YFDG EXTRACELLULAR OB2955 BH3736 GBS0884 SMU.1524C 7 59 5.0E-15 T 21-04-2016 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA HSISS4_RS04325 96beaee6386b6f31ee648a80bc957ecc 62 Pfam PF11772 DNA-directed RNA polymerase subunit beta 15 61 2.3E-18 T 21-04-2016 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA HSISS4_RS02910 9a1f818f6ecd704e3eed2aa447bff50b 134 Gene3D G3DSA:1.10.3830.10 9 129 8.1E-43 T 21-04-2016 HSISS4_RS02910 9a1f818f6ecd704e3eed2aa447bff50b 134 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 76 87 - T 21-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 HSISS4_RS02910 9a1f818f6ecd704e3eed2aa447bff50b 134 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 124 1.4E-33 T 21-04-2016 IPR000829 Diacylglycerol kinase, prokaryotic GO:0004143|GO:0008654|GO:0016020 KEGG: 00500+2.7.1.10|KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039 HSISS4_RS02910 9a1f818f6ecd704e3eed2aa447bff50b 134 PANTHER PTHR34299 3 134 4.5E-36 T 21-04-2016 HSISS4_RS02910 9a1f818f6ecd704e3eed2aa447bff50b 134 PANTHER PTHR34299:SF1 3 134 4.5E-36 T 21-04-2016 HSISS4_RS07055 609f04525d37bbd9a492ea18bda5129f 231 Gene3D G3DSA:3.40.50.880 2 230 4.0E-54 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS07055 609f04525d37bbd9a492ea18bda5129f 231 PANTHER PTHR11922:SF18 30 231 3.9E-48 T 21-04-2016 HSISS4_RS07055 609f04525d37bbd9a492ea18bda5129f 231 PANTHER PTHR11922 30 231 3.9E-48 T 21-04-2016 HSISS4_RS07055 609f04525d37bbd9a492ea18bda5129f 231 SUPERFAMILY SSF52317 1 228 1.83E-35 T 21-04-2016 IPR029062 Class I glutamine amidotransferase-like HSISS4_RS07055 609f04525d37bbd9a492ea18bda5129f 231 Pfam PF07722 Peptidase C26 4 211 5.4E-73 T 21-04-2016 IPR011697 Peptidase C26 GO:0006541|GO:0016787 HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 SUPERFAMILY SSF56300 5 171 3.26E-46 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 Gene3D G3DSA:3.60.21.10 4 170 1.4E-44 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 6 139 3.9E-22 T 21-04-2016 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 PANTHER PTHR11124:SF14 1 160 2.3E-47 T 21-04-2016 HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 6 154 2.2E-22 T 21-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HSISS4_RS01230 25dfdf6526d6afcd9e349ba985b3d62f 173 PANTHER PTHR11124 1 160 2.3E-47 T 21-04-2016 IPR000979 Phosphodiesterase MJ0936/Vps29 HSISS4_RS05900 ce08322dbd36968cdda71be60a4daba7 112 Pfam PF03477 ATP cone domain 1 92 2.3E-20 T 21-04-2016 IPR005144 ATP-cone domain HSISS4_RS05900 ce08322dbd36968cdda71be60a4daba7 112 PANTHER PTHR21075 1 96 2.2E-18 T 21-04-2016 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 Gene3D G3DSA:3.30.1240.10 87 182 4.0E-44 T 21-04-2016 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 PANTHER PTHR10000 1 269 5.9E-104 T 21-04-2016 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 ProSitePatterns PS01228 Hypothetical cof family signature 1. 5 16 - T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 Gene3D G3DSA:3.40.50.1000 183 268 9.1E-59 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 Gene3D G3DSA:3.40.50.1000 1 76 9.1E-59 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 PANTHER PTHR10000:SF16 1 269 5.9E-104 T 21-04-2016 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 SUPERFAMILY SSF56784 1 268 9.85E-81 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 263 4.4E-68 T 21-04-2016 IPR000150 Cof protein GO:0016787 HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 263 1.7E-69 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04405 cf05b96cd3422f803bdadabfa3b9acf2 269 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 236 5.7E-32 T 21-04-2016 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: REACT_17015 HSISS4_RS05010 d7f3c472a661d115ac7785d1968b49bc 376 TIGRFAM TIGR02672 cas_csm6: CRISPR type III-A/MTUBE-associated protein Csm6 13 374 3.8E-129 T 21-04-2016 IPR013489 CRISPR-associated protein Csm6 HSISS4_RS05010 d7f3c472a661d115ac7785d1968b49bc 376 Pfam PF09659 CRISPR-associated protein (Cas_Csm6) 20 373 2.3E-38 T 21-04-2016 IPR013489 CRISPR-associated protein Csm6 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 SUPERFAMILY SSF47005 116 160 2.75E-11 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 SUPERFAMILY SSF51230 1 95 1.57E-24 T 21-04-2016 IPR011053 Single hybrid motif HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 185 407 3.1E-70 T 21-04-2016 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Gene3D G3DSA:3.30.559.10 180 408 1.5E-70 T 21-04-2016 IPR023213 Chloramphenicol acetyltransferase-like domain HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Pfam PF00364 Biotin-requiring enzyme 4 72 1.2E-17 T 21-04-2016 IPR000089 Biotin/lipoyl attachment HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Pfam PF02817 e3 binding domain 123 157 1.4E-13 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Gene3D G3DSA:2.40.50.100 1 95 3.4E-26 T 21-04-2016 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 PANTHER PTHR23151 3 409 1.1E-123 T 21-04-2016 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 Gene3D G3DSA:4.10.320.10 113 161 1.7E-17 T 21-04-2016 IPR004167 E3-binding domain GO:0008152|GO:0016746 HSISS4_RS03240 44f06fca0ccee5ee8da6ee3bc43368eb 409 SUPERFAMILY SSF52777 182 408 2.94E-69 T 21-04-2016 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 SUPERFAMILY SSF47648 1 67 4.84E-22 T 21-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 PANTHER PTHR10515:SF0 1 425 1.9E-184 T 21-04-2016 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 SUPERFAMILY SSF52418 69 318 8.37E-84 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 21-04-2016 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 408 6.7E-167 T 21-04-2016 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|UniPathway: UPA00578 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Gene3D G3DSA:3.40.1030.10 70 323 4.4E-108 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Gene3D G3DSA:1.20.970.10 1 67 3.0E-30 T 21-04-2016 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 3.6E-21 T 21-04-2016 IPR017459 Glycosyl transferase family 3, N-terminal domain HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 SMART SM00941 338 411 8.0E-18 T 21-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Gene3D G3DSA:3.90.1170.30 325 413 2.8E-25 T 21-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 PIRSF PIRSF000478 1 425 1.0E-152 T 21-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 SUPERFAMILY SSF54680 325 421 2.35E-20 T 21-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Pfam PF00591 Glycosyl transferase family, a/b domain 78 295 2.8E-37 T 21-04-2016 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 338 408 2.3E-19 T 21-04-2016 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 HSISS4_RS05645 5aec2cddde80bb3a197de02ff84ef581 425 PANTHER PTHR10515 1 425 1.9E-184 T 21-04-2016 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 HSISS4_RS07880 fff57c969dfc604cc7236b8084b227a9 490 SUPERFAMILY SSF53756 232 477 3.61E-34 T 21-04-2016 HSISS4_RS07880 fff57c969dfc604cc7236b8084b227a9 490 PANTHER PTHR12526 299 486 2.0E-26 T 21-04-2016 HSISS4_RS07880 fff57c969dfc604cc7236b8084b227a9 490 Pfam PF00534 Glycosyl transferases group 1 310 435 6.1E-24 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS07880 fff57c969dfc604cc7236b8084b227a9 490 Gene3D G3DSA:3.40.50.2000 301 456 8.3E-15 T 21-04-2016 HSISS4_RS07880 fff57c969dfc604cc7236b8084b227a9 490 Hamap MF_01472 Glycosyltransferase Gtf1 [gtf1]. 2 489 28.602 T 21-04-2016 IPR014267 Glycosyltransferase Gtf1 GO:0016757 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.- HSISS4_RS07955 736b3af0418c496e39e3421769363d5f 688 PANTHER PTHR10110:SF120 5 680 3.4E-144 T 21-04-2016 HSISS4_RS07955 736b3af0418c496e39e3421769363d5f 688 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 1.8E-42 T 21-04-2016 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 HSISS4_RS07955 736b3af0418c496e39e3421769363d5f 688 PANTHER PTHR10110 5 680 3.4E-144 T 21-04-2016 IPR018422 Cation/H+ exchanger, CPA1 family GO:0006812|GO:0015299|GO:0016021 Reactome: REACT_15518 HSISS4_RS07045 49dff1a5eae901f864d5b482431f6c17 115 Gene3D G3DSA:3.30.1820.10 1 112 2.0E-50 T 21-04-2016 IPR014965 Putative amino acid metabolism HSISS4_RS07045 49dff1a5eae901f864d5b482431f6c17 115 Pfam PF08866 Putative amino acid metabolism 1 111 2.2E-46 T 21-04-2016 IPR014965 Putative amino acid metabolism HSISS4_RS07045 49dff1a5eae901f864d5b482431f6c17 115 SUPERFAMILY SSF160800 1 112 1.7E-45 T 21-04-2016 IPR014965 Putative amino acid metabolism HSISS4_RS06335 ab0e8358bab1e95d2d9b10f56e7e5160 210 Pfam PF00881 Nitroreductase family 14 190 1.4E-31 T 21-04-2016 IPR029479 Nitroreductase HSISS4_RS06335 ab0e8358bab1e95d2d9b10f56e7e5160 210 PANTHER PTHR23026 1 209 2.0E-49 T 21-04-2016 HSISS4_RS06335 ab0e8358bab1e95d2d9b10f56e7e5160 210 PANTHER PTHR23026:SF111 1 209 2.0E-49 T 21-04-2016 HSISS4_RS06335 ab0e8358bab1e95d2d9b10f56e7e5160 210 Gene3D G3DSA:3.40.109.10 3 209 3.9E-59 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS06335 ab0e8358bab1e95d2d9b10f56e7e5160 210 SUPERFAMILY SSF55469 7 208 8.11E-56 T 21-04-2016 IPR000415 Nitroreductase-like GO:0016491 HSISS4_RS09560 33d66252a9221629ba00bb4b34ebeed7 194 Pfam PF08006 Protein of unknown function (DUF1700) 1 189 3.7E-19 T 21-04-2016 IPR012963 Protein of unknown function DUF1700 HSISS4_RS02680 0d875072c606ac575306319ee4990aed 312 Gene3D G3DSA:3.40.50.1820 41 309 6.6E-29 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS02680 0d875072c606ac575306319ee4990aed 312 SUPERFAMILY SSF53474 37 307 2.21E-23 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS02680 0d875072c606ac575306319ee4990aed 312 PANTHER PTHR10992 1 309 2.9E-14 T 21-04-2016 HSISS4_RS03630 a348696cb47a40d606f92c2bf2638e94 380 Hamap MF_00912 Cell division protein DivIB [divIB]. 50 313 25.503 T 21-04-2016 IPR026580 Cell division protein DivIB HSISS4_RS03630 a348696cb47a40d606f92c2bf2638e94 380 Pfam PF08478 POTRA domain, FtsQ-type 112 181 6.4E-14 T 21-04-2016 IPR013685 Polypeptide-transport-associated, FtsQ-type HSISS4_RS03630 a348696cb47a40d606f92c2bf2638e94 380 PANTHER PTHR37820 90 352 3.1E-34 T 21-04-2016 HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 SUPERFAMILY SSF52540 3 221 1.25E-54 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 SMART SM00382 30 204 2.7E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 PANTHER PTHR24220 7 223 4.0E-73 T 21-04-2016 HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 Pfam PF00005 ABC transporter 21 156 8.5E-26 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 Gene3D G3DSA:3.40.50.300 2 222 1.6E-58 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS06085 7991b545b7309cd00562838d277c8440 293 PANTHER PTHR24220:SF165 7 223 4.0E-73 T 21-04-2016 HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 Gene3D G3DSA:3.40.630.30 24 148 9.0E-28 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 PANTHER PTHR23091:SF122 14 149 4.8E-23 T 21-04-2016 HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 SUPERFAMILY SSF55729 18 149 4.75E-27 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 PANTHER PTHR23091 14 149 4.8E-23 T 21-04-2016 HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 Pfam PF13508 Acetyltransferase (GNAT) domain 52 127 3.2E-14 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS08530 1ba760f637d150a69241411f8b41b045 151 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 21 146 1.7E-37 T 21-04-2016 IPR006464 Ribosomal-protein-alanine acetyltransferase GO:0006474|GO:0016407 HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 Pfam PF05979 Bacterial protein of unknown function (DUF896) 4 67 1.7E-30 T 21-04-2016 IPR009242 Protein of unknown function DUF896 HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 Gene3D G3DSA:1.10.287.540 1 59 4.4E-29 T 21-04-2016 IPR023218 UPF0291 structural domain HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 PANTHER PTHR37300 1 78 2.4E-39 T 21-04-2016 HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 Hamap MF_01103 UPF0291 protein . 1 59 16.82 T 21-04-2016 IPR009242 Protein of unknown function DUF896 HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 PANTHER PTHR37300:SF1 1 78 2.4E-39 T 21-04-2016 HSISS4_RS02385 86dd67a0142870cabd466132ad8e1987 85 SUPERFAMILY SSF158221 1 41 1.44E-13 T 21-04-2016 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 Gene3D G3DSA:3.30.110.60 1 97 2.4E-30 T 21-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 5.1E-20 T 21-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 PANTHER PTHR31846 1 102 1.2E-28 T 21-04-2016 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 93 1.0E-42 T 21-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 SMART SM01103 3 86 3.0E-35 T 21-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 SUPERFAMILY SSF75471 1 96 3.53E-28 T 21-04-2016 IPR001890 RNA-binding, CRM domain GO:0003723 HSISS4_RS07830 14ff4c72acd8941eeaaa0f5132032f38 105 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 95 1.6E-25 T 21-04-2016 IPR017924 RNA-binding protein YhbY GO:0003723 HSISS4_RS03215 45449e30d8f43ab3ef88a451bed2e854 79 Pfam PF04226 Transglycosylase associated protein 31 75 3.4E-10 T 21-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 HSISS4_RS06825 6a68ba80a6b258891ff3c6d2e0919c93 509 Pfam PF07006 Protein of unknown function (DUF1310) 13 118 4.5E-13 T 21-04-2016 IPR010738 Protein of unknown function DUF1310 HSISS4_RS06825 6a68ba80a6b258891ff3c6d2e0919c93 509 Pfam PF11311 Protein of unknown function (DUF3114) 184 440 2.0E-20 T 21-04-2016 IPR021462 Protein of unknown function DUF3114 HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 SUPERFAMILY SSF55729 163 239 9.53E-30 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 SUPERFAMILY SSF46589 239 303 1.26E-16 T 21-04-2016 IPR010978 tRNA-binding arm GO:0000166 Reactome: REACT_71 HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 Gene3D G3DSA:3.40.630.30 1 161 1.0E-44 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 PANTHER PTHR36174 1 410 6.3E-144 T 21-04-2016 HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 Gene3D G3DSA:3.40.630.30 305 382 3.1E-47 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 Gene3D G3DSA:3.40.630.30 162 238 3.1E-47 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 PANTHER PTHR36174:SF2 1 410 6.3E-144 T 21-04-2016 HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 SUPERFAMILY SSF55729 1 159 1.38E-44 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 Pfam PF02388 FemAB family 7 406 2.2E-150 T 21-04-2016 IPR003447 FemABX peptidyl transferase GO:0009252|GO:0016755 HSISS4_RS02820 3b98586e4953a92419f67d28e30d434d 411 SUPERFAMILY SSF55729 306 402 9.53E-30 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 PANTHER PTHR10344 1 209 2.0E-66 T 21-04-2016 HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 Hamap MF_00165 Thymidylate kinase [tmk]. 5 209 30.527 T 21-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 199 2.0E-58 T 21-04-2016 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 ProSitePatterns PS01331 Thymidylate kinase signature. 95 107 - T 21-04-2016 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 Gene3D G3DSA:3.40.50.300 3 209 4.0E-71 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 Pfam PF02223 Thymidylate kinase 9 200 6.2E-53 T 21-04-2016 HSISS4_RS02305 0ca1d7a8f13a43b54e179e3465e0f733 209 SUPERFAMILY SSF52540 1 208 7.86E-52 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS00995 6cf1982736896cdacdd8d9826bc2d066 234 Pfam PF14373 Superinfection immunity protein 169 201 7.6E-9 T 21-04-2016 IPR016410 Bacteriophage-associated immunity protein HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 SUPERFAMILY SSF52540 34 216 5.17E-41 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 PANTHER PTHR32309 11 232 1.8E-62 T 21-04-2016 HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 Pfam PF13614 AAA domain 35 178 1.0E-18 T 21-04-2016 IPR025669 AAA domain HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 PANTHER PTHR32309:SF13 11 232 1.8E-62 T 21-04-2016 HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 19 222 3.3E-98 T 21-04-2016 IPR005702 Exopolysaccharide synthesis protein GO:0045226 HSISS4_RS04600 f359b98675df1475c283fc465e907f93 246 Gene3D G3DSA:3.40.50.300 35 213 4.5E-40 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 Gene3D G3DSA:3.40.50.300 4 241 3.0E-89 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 Pfam PF00005 ABC transporter 21 169 3.1E-37 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 PANTHER PTHR24220:SF327 7 244 3.5E-142 T 21-04-2016 HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 SUPERFAMILY SSF52540 5 239 4.66E-83 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 PIRSF PIRSF039085 2 244 6.9E-118 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 PANTHER PTHR24220 7 244 3.5E-142 T 21-04-2016 HSISS4_RS02860 42cb330a1a92c5755e133ed277c955a6 244 SMART SM00382 30 217 6.0E-16 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS03435 0b030dd5a9e3e1e3bbf7ce7972ec175d 212 SMART SM00855 2 160 1.3E-18 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS03435 0b030dd5a9e3e1e3bbf7ce7972ec175d 212 PANTHER PTHR23029 1 209 6.8E-42 T 21-04-2016 HSISS4_RS03435 0b030dd5a9e3e1e3bbf7ce7972ec175d 212 Gene3D G3DSA:3.40.50.1240 1 208 3.2E-57 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS03435 0b030dd5a9e3e1e3bbf7ce7972ec175d 212 SUPERFAMILY SSF53254 1 207 1.08E-52 T 21-04-2016 IPR029033 Histidine phosphatase superfamily HSISS4_RS03435 0b030dd5a9e3e1e3bbf7ce7972ec175d 212 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 202 4.7E-49 T 21-04-2016 IPR013078 Histidine phosphatase superfamily, clade-1 HSISS4_RS07965 fd8326a873f0367b46a72d0722e4c77b 182 PANTHER PTHR35276:SF1 2 182 4.2E-45 T 21-04-2016 HSISS4_RS07965 fd8326a873f0367b46a72d0722e4c77b 182 Pfam PF06962 Putative rRNA methylase 44 179 3.4E-50 T 21-04-2016 IPR010719 Putative rRNA methylase KEGG: 00253+2.1.1.-|KEGG: 00270+2.1.1.-|KEGG: 00332+2.1.1.-|KEGG: 00340+2.1.1.-|KEGG: 00350+2.1.1.-|KEGG: 00360+2.1.1.-|KEGG: 00380+2.1.1.-|KEGG: 00450+2.1.1.-|KEGG: 00522+2.1.1.-|KEGG: 00523+2.1.1.-|KEGG: 00624+2.1.1.-|KEGG: 00627+2.1.1.-|KEGG: 00860+2.1.1.-|KEGG: 00940+2.1.1.-|KEGG: 00941+2.1.1.-|KEGG: 00942+2.1.1.-|KEGG: 00945+2.1.1.-|KEGG: 00950+2.1.1.-|KEGG: 00981+2.1.1.- HSISS4_RS07965 fd8326a873f0367b46a72d0722e4c77b 182 PANTHER PTHR35276 2 182 4.2E-45 T 21-04-2016 HSISS4_RS07965 fd8326a873f0367b46a72d0722e4c77b 182 SUPERFAMILY SSF53335 10 142 1.75E-19 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07965 fd8326a873f0367b46a72d0722e4c77b 182 Gene3D G3DSA:3.40.50.150 19 140 3.3E-14 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS07395 4c64ba756d0cbdd1af75cd5410a72106 82 PANTHER PTHR34654 2 82 1.2E-23 T 21-04-2016 HSISS4_RS07395 4c64ba756d0cbdd1af75cd5410a72106 82 Hamap MF_00088 UPF0109 protein . 4 77 16.266 T 21-04-2016 IPR020627 Uncharacterised protein family UPF0109 HSISS4_RS07395 4c64ba756d0cbdd1af75cd5410a72106 82 Gene3D G3DSA:3.30.300.120 12 77 1.8E-8 T 21-04-2016 HSISS4_RS07395 4c64ba756d0cbdd1af75cd5410a72106 82 Pfam PF13083 KH domain 6 76 4.2E-16 T 21-04-2016 HSISS4_RS04305 a6b70e1e880b154cba09e9aafaad8b60 473 SUPERFAMILY SSF51445 77 197 4.02E-9 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS04305 a6b70e1e880b154cba09e9aafaad8b60 473 Gene3D G3DSA:3.20.20.80 76 214 7.2E-11 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS04305 a6b70e1e880b154cba09e9aafaad8b60 473 Pfam PF16116 Domain of unknown function (DUF4832) 247 449 7.4E-23 T 21-04-2016 IPR032267 Domain of unknown function DUF4832 HSISS4_RS04305 a6b70e1e880b154cba09e9aafaad8b60 473 Pfam PF02449 Beta-galactosidase 82 187 3.5E-4 T 21-04-2016 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 HSISS4_RS04610 5355b5dcbf7e1863d97a4fcac9482386 390 SUPERFAMILY SSF53756 61 389 3.98E-37 T 21-04-2016 HSISS4_RS04610 5355b5dcbf7e1863d97a4fcac9482386 390 Pfam PF09314 Domain of unknown function (DUF1972) 3 193 2.4E-89 T 21-04-2016 IPR015393 Domain of unknown function DUF1972 HSISS4_RS00690 914cfa439f8cfceb82a8d7e6d63e05e2 253 Pfam PF08543 Phosphomethylpyrimidine kinase 13 247 1.2E-63 T 21-04-2016 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase UniPathway: UPA00647 HSISS4_RS00690 914cfa439f8cfceb82a8d7e6d63e05e2 253 PANTHER PTHR20858 1 248 7.0E-63 T 21-04-2016 HSISS4_RS00690 914cfa439f8cfceb82a8d7e6d63e05e2 253 SUPERFAMILY SSF53613 5 247 2.65E-56 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS00690 914cfa439f8cfceb82a8d7e6d63e05e2 253 Gene3D G3DSA:3.40.1190.20 6 247 2.0E-66 T 21-04-2016 IPR029056 Ribokinase-like HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 96 1.3E-28 T 21-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 Gene3D G3DSA:3.30.160.100 3 95 4.4E-33 T 21-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 125 178 1.4E-27 T 21-04-2016 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 SUPERFAMILY SSF69754 3 109 3.92E-31 T 21-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 3 103 5.2E-30 T 21-04-2016 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 HSISS4_RS01685 c929da36c76c753a4fb75e0ce5592d14 182 PANTHER PTHR33231 1 182 4.5E-60 T 21-04-2016 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 Gene3D G3DSA:1.10.287.130 82 140 3.3E-8 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 191 279 6.5E-6 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 PANTHER PTHR24423 2 16 1.3E-21 T 21-04-2016 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 PANTHER PTHR24423 34 50 1.3E-21 T 21-04-2016 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 PANTHER PTHR24423 77 281 1.3E-21 T 21-04-2016 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 SMART SM00388 81 144 1.1E-5 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 Pfam PF00512 His Kinase A (phospho-acceptor) domain 86 144 9.3E-7 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 SUPERFAMILY SSF55874 151 282 3.15E-16 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 Gene3D G3DSA:3.30.565.10 146 283 2.7E-16 T 21-04-2016 IPR003594 Histidine kinase-like ATPase, C-terminal domain HSISS4_RS06325 ae2bdb680589809bcb407f0f31c92faa 291 SUPERFAMILY SSF47384 76 144 1.04E-8 T 21-04-2016 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 SUPERFAMILY SSF102645 1 225 6.02E-52 T 21-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 Gene3D G3DSA:3.40.50.10300 1 225 8.9E-55 T 21-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 TIGRFAM TIGR02114 coaB_strep: phosphopantothenate--cysteine ligase 1 224 6.5E-105 T 21-04-2016 IPR011848 Phosphopantothenate--cysteine ligase HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 2 191 2.9E-35 T 21-04-2016 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|UniPathway: UPA00241 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 PANTHER PTHR14359:SF22 1 96 8.2E-72 T 21-04-2016 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 PANTHER PTHR14359:SF22 117 224 8.2E-72 T 21-04-2016 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 PANTHER PTHR14359 1 96 8.2E-72 T 21-04-2016 HSISS4_RS05680 d26e9a6f61044b2d8b0bb9232f5049c5 227 PANTHER PTHR14359 117 224 8.2E-72 T 21-04-2016 HSISS4_RS07535 710cc0eab06b49821153e1ad70114046 89 Pfam PF01541 GIY-YIG catalytic domain 8 78 2.5E-17 T 21-04-2016 IPR000305 GIY-YIG nuclease superfamily HSISS4_RS07535 710cc0eab06b49821153e1ad70114046 89 PANTHER PTHR34477:SF1 1 85 4.0E-38 T 21-04-2016 HSISS4_RS07535 710cc0eab06b49821153e1ad70114046 89 SUPERFAMILY SSF82771 7 79 2.48E-14 T 21-04-2016 IPR000305 GIY-YIG nuclease superfamily HSISS4_RS07535 710cc0eab06b49821153e1ad70114046 89 PANTHER PTHR34477 1 85 4.0E-38 T 21-04-2016 HSISS4_RS02370 85d11d622f23205c95f06d6fcb52b212 414 PANTHER PTHR37814 1 367 9.8E-67 T 21-04-2016 HSISS4_RS02370 85d11d622f23205c95f06d6fcb52b212 414 PANTHER PTHR37814:SF1 1 367 9.8E-67 T 21-04-2016 HSISS4_RS06655 f6770756df5af97721fecbea837c3323 252 Pfam PF02517 CAAX protease self-immunity 153 238 1.7E-7 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS06720 6b697103c266c0c89d4daed9c6d68876 333 SUPERFAMILY SSF53756 88 308 1.07E-5 T 21-04-2016 HSISS4_RS06720 6b697103c266c0c89d4daed9c6d68876 333 PIRSF PIRSF007023 1 333 3.6E-115 T 21-04-2016 IPR016503 UDP-galactofuranosyltransferase GO:0016757 HSISS4_RS06720 6b697103c266c0c89d4daed9c6d68876 333 SUPERFAMILY SSF53756 69 149 5.18E-6 T 21-04-2016 HSISS4_RS08180 5494b0c6279928d5243187e5bf72e460 130 Pfam PF05656 Protein of unknown function (DUF805) 12 117 4.2E-17 T 21-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 HSISS4_RS05525 22bfee7e367ceeb95850a52159b6d332 465 PANTHER PTHR12994:SF17 1 403 1.9E-60 T 21-04-2016 HSISS4_RS05525 22bfee7e367ceeb95850a52159b6d332 465 PANTHER PTHR12994 1 403 1.9E-60 T 21-04-2016 HSISS4_RS05525 22bfee7e367ceeb95850a52159b6d332 465 Pfam PF03577 Peptidase family C69 2 402 2.5E-197 T 21-04-2016 IPR005322 Peptidase C69, dipeptidase A GO:0006508|GO:0016805 HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 PANTHER PTHR10366 6 345 1.6E-193 T 21-04-2016 HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 Gene3D G3DSA:3.40.50.720 3 193 6.5E-59 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 7 330 2.5E-134 T 21-04-2016 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688 HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 PANTHER PTHR10366:SF437 6 345 1.6E-193 T 21-04-2016 HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 SUPERFAMILY SSF51735 5 336 3.82E-94 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 Gene3D G3DSA:3.90.25.10 194 333 2.6E-48 T 21-04-2016 HSISS4_RS03830 36663a99e775c9711be7f0492dfd15aa 348 Pfam PF16363 GDP-mannose 4,6 dehydratase 8 318 3.6E-75 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS01950 08fc679b9d229913196bc8a7978adeea 167 Pfam PF03729 Short repeat of unknown function (DUF308) 65 114 9.8E-4 T 21-04-2016 IPR005325 Protein of unknown function DUF308, membrane HSISS4_RS01950 08fc679b9d229913196bc8a7978adeea 167 Pfam PF03729 Short repeat of unknown function (DUF308) 7 76 4.9E-14 T 21-04-2016 IPR005325 Protein of unknown function DUF308, membrane HSISS4_RS03500 931f337003f41f36645753fe68a9905a 121 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 36 109 7.3E-22 T 21-04-2016 IPR009241 Toxin HigB-like HSISS4_RS00880 4454817a7725fd80aca7a1b9baaf5691 472 Pfam PF01458 Uncharacterized protein family (UPF0051) 218 443 4.1E-75 T 21-04-2016 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 HSISS4_RS00880 4454817a7725fd80aca7a1b9baaf5691 472 SUPERFAMILY SSF101960 39 469 7.59E-138 T 21-04-2016 HSISS4_RS00880 4454817a7725fd80aca7a1b9baaf5691 472 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 17 463 3.4E-218 T 21-04-2016 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 HSISS4_RS00880 4454817a7725fd80aca7a1b9baaf5691 472 PANTHER PTHR30508 17 472 1.6E-230 T 21-04-2016 HSISS4_RS00880 4454817a7725fd80aca7a1b9baaf5691 472 PANTHER PTHR30508:SF1 17 472 1.6E-230 T 21-04-2016 HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 Hamap MF_00238 Cytidylate kinase [cmk]. 4 223 33.422 T 21-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 Pfam PF02224 Cytidylate kinase 6 220 3.0E-73 T 21-04-2016 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 218 8.3E-76 T 21-04-2016 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 MetaCyc: PWY-7205 HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 PANTHER PTHR21299 6 223 2.4E-71 T 21-04-2016 HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 SUPERFAMILY SSF52540 1 222 1.55E-45 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04495 ee6231a46300d0bdbb313ed376bce86a 226 Gene3D G3DSA:3.40.50.300 3 220 4.3E-73 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07890 3a4e45b288828ab435c1ad2570183285 293 PANTHER PTHR22916:SF24 1 218 5.1E-64 T 21-04-2016 HSISS4_RS07890 3a4e45b288828ab435c1ad2570183285 293 Pfam PF00535 Glycosyl transferase family 2 8 131 3.0E-39 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS07890 3a4e45b288828ab435c1ad2570183285 293 PANTHER PTHR22916 1 218 5.1E-64 T 21-04-2016 HSISS4_RS07890 3a4e45b288828ab435c1ad2570183285 293 Gene3D G3DSA:3.90.550.10 2 207 2.0E-60 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07890 3a4e45b288828ab435c1ad2570183285 293 SUPERFAMILY SSF53448 7 229 9.25E-59 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS02505 e4ec23214154032329c9ce72fd30edd7 325 Gene3D G3DSA:3.40.50.300 36 141 1.0E-13 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS02505 e4ec23214154032329c9ce72fd30edd7 325 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 3 142 2.0E-17 T 21-04-2016 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 HSISS4_RS02505 e4ec23214154032329c9ce72fd30edd7 325 Pfam PF05257 CHAP domain 200 299 1.3E-15 T 21-04-2016 IPR007921 CHAP domain HSISS4_RS02505 e4ec23214154032329c9ce72fd30edd7 325 SUPERFAMILY SSF54001 196 306 1.08E-15 T 21-04-2016 HSISS4_RS06010 8c6578a31d80a3e76dc9964146810a04 306 Pfam PF13536 Putative multidrug resistance efflux transporter 44 298 2.1E-92 T 21-04-2016 IPR032713 Putative multidrug resistance efflux transporter HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 Hamap MF_01241 Glucosamine-6-phosphate deaminase [nagB]. 1 233 40.676 T 21-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 SUPERFAMILY SSF100950 1 233 6.8E-81 T 21-04-2016 HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 ProSitePatterns PS01161 Glucosamine/galactosamine-6-phosphate isomerases signature. 112 130 - T 21-04-2016 IPR018321 Glucosamine-6-phosphate isomerase, conserved site GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 Gene3D G3DSA:3.40.50.1360 1 233 1.8E-83 T 21-04-2016 HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 PANTHER PTHR11280 1 233 6.8E-99 T 21-04-2016 IPR004547 Glucosamine-6-phosphate isomerase GO:0004342|GO:0006044 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906|UniPathway: UPA00629 HSISS4_RS02535 e78dbd030cbfd911aa5ab0c1963fea0a 233 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 25 219 7.6E-18 T 21-04-2016 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 HSISS4_RS08060 28f014460c937a7ac76b55bc6ef01c3a 223 Pfam PF02517 CAAX protease self-immunity 125 209 1.0E-14 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 273 6.0E-81 T 21-04-2016 IPR003797 DegV HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 Gene3D G3DSA:3.30.1180.10 153 277 2.1E-38 T 21-04-2016 HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 PANTHER PTHR33434:SF2 1 277 6.6E-62 T 21-04-2016 HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 PANTHER PTHR33434 1 277 6.6E-62 T 21-04-2016 HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 Gene3D G3DSA:3.40.50.10170 1 150 3.1E-36 T 21-04-2016 HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 275 2.7E-78 T 21-04-2016 IPR003797 DegV HSISS4_RS01930 4c361fea438ac6942151dfe26b85f09f 280 SUPERFAMILY SSF82549 1 276 8.63E-78 T 21-04-2016 HSISS4_RS01905 05c5ef444a012632a245e2cf201a2f6c 178 Gene3D G3DSA:3.40.630.30 13 141 1.7E-28 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01905 05c5ef444a012632a245e2cf201a2f6c 178 Pfam PF13508 Acetyltransferase (GNAT) domain 47 134 2.7E-8 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS01905 05c5ef444a012632a245e2cf201a2f6c 178 SUPERFAMILY SSF55729 7 144 1.61E-15 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 Gene3D G3DSA:3.20.20.220 2 280 1.2E-89 T 21-04-2016 IPR029041 FAD-linked oxidoreductase-like HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 Pfam PF02219 Methylenetetrahydrofolate reductase 4 276 1.0E-69 T 21-04-2016 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 8 277 9.2E-100 T 21-04-2016 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|UniPathway: UPA00193 HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 PANTHER PTHR21091:SF31 136 268 4.6E-27 T 21-04-2016 HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 PANTHER PTHR21091 136 268 4.6E-27 T 21-04-2016 HSISS4_RS05700 7068e1487bc147e947c955722f5a0e4a 291 SUPERFAMILY SSF51730 3 279 5.3E-79 T 21-04-2016 IPR029041 FAD-linked oxidoreductase-like HSISS4_RS00750 d5c3af873f6a589d73ec66c724939a50 156 Pfam PF11217 Protein of unknown function (DUF3013) 1 155 1.1E-63 T 21-04-2016 IPR021380 Protein of unknown function DUF3013 HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 SMART SM00382 28 216 3.3E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 PIRSF PIRSF039085 1 245 1.3E-101 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 Pfam PF00005 ABC transporter 19 168 2.7E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 Gene3D G3DSA:3.40.50.300 2 241 1.6E-80 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 PANTHER PTHR24220 5 253 1.6E-135 T 21-04-2016 HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 SUPERFAMILY SSF52540 3 237 3.9E-77 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04350 2f61abecb05e3f1e6ca7384731739fe3 255 PANTHER PTHR24220:SF474 5 253 1.6E-135 T 21-04-2016 HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 SMART SM00382 28 216 3.3E-13 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 PIRSF PIRSF039085 1 245 1.3E-101 T 21-04-2016 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 21-04-2016 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 Pfam PF00005 ABC transporter 19 168 2.7E-36 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 Gene3D G3DSA:3.40.50.300 2 241 1.6E-80 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 PANTHER PTHR24220 5 253 1.6E-135 T 21-04-2016 HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 SUPERFAMILY SSF52540 3 237 3.9E-77 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS04375 2f61abecb05e3f1e6ca7384731739fe3 255 PANTHER PTHR24220:SF474 5 253 1.6E-135 T 21-04-2016 HSISS4_RS04485 8b05a5c1c1a929bbab164b98d28006d6 166 ProDom PD091538 PORE-FORMING FORMING PORE PEPTIDE EBSA PEPTIDE GBS1458 SMU.692 SAG1388 7 135 3.0E-67 T 21-04-2016 IPR020215 Pore-forming protein, EbsA HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 SUPERFAMILY SSF51569 6 341 2.41E-93 T 21-04-2016 HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 14 342 6.4E-77 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 Pfam PF00793 DAHP synthetase I family 35 333 4.5E-49 T 21-04-2016 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674|UniPathway: UPA00030|UniPathway: UPA00357 HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 Gene3D G3DSA:3.20.20.70 4 342 3.4E-105 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 PANTHER PTHR21225 4 341 2.7E-161 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS08330 72921110bda2567c6516f88732a08614 343 PIRSF PIRSF001361 1 343 5.5E-115 T 21-04-2016 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164|UniPathway: UPA00053 HSISS4_RS01195 ec9383a17ae639f4b74c9027f32d86b3 229 PANTHER PTHR23291:SF42 2 229 7.3E-64 T 21-04-2016 HSISS4_RS01195 ec9383a17ae639f4b74c9027f32d86b3 229 PANTHER PTHR23291 2 229 7.3E-64 T 21-04-2016 IPR006214 Bax inhibitor 1-related HSISS4_RS01195 ec9383a17ae639f4b74c9027f32d86b3 229 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 16 225 4.2E-54 T 21-04-2016 HSISS4_RS09595 c74d4781ae55495c892a58b0024c9fbb 100 PANTHER PTHR40026 6 98 3.5E-24 T 21-04-2016 HSISS4_RS09595 c74d4781ae55495c892a58b0024c9fbb 100 Pfam PF06257 Biofilm formation stimulator VEG 10 86 8.2E-25 T 21-04-2016 IPR009366 Protein Veg GO:0042710 HSISS4_RS09595 c74d4781ae55495c892a58b0024c9fbb 100 Gene3D G3DSA:2.30.30.100 1 89 1.7E-29 T 21-04-2016 HSISS4_RS09595 c74d4781ae55495c892a58b0024c9fbb 100 PIRSF PIRSF037257 1 97 5.0E-30 T 21-04-2016 IPR009366 Protein Veg GO:0042710 HSISS4_RS09595 c74d4781ae55495c892a58b0024c9fbb 100 PANTHER PTHR40026:SF1 6 98 3.5E-24 T 21-04-2016 IPR009366 Protein Veg GO:0042710 HSISS4_RS06620 a68e51fd88b23bd7b63d043927c2e11d 315 PANTHER PTHR36838 3 315 5.3E-30 T 21-04-2016 HSISS4_RS06620 a68e51fd88b23bd7b63d043927c2e11d 315 Pfam PF03547 Membrane transport protein 7 157 6.5E-18 T 21-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HSISS4_RS06620 a68e51fd88b23bd7b63d043927c2e11d 315 Pfam PF03547 Membrane transport protein 173 309 6.7E-11 T 21-04-2016 IPR004776 Auxin efflux carrier GO:0016021|GO:0055085 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 133 145 - T 21-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 244 6.5E-70 T 21-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 4 255 18.131 T 21-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 7 249 4.3E-78 T 21-04-2016 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 UniPathway: UPA00664 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 PANTHER PTHR30589:SF0 1 261 1.4E-103 T 21-04-2016 HSISS4_RS03335 80c83b451a122bb19ec3959aa9166d4e 263 PANTHER PTHR30589 1 261 1.4E-103 T 21-04-2016 HSISS4_RS08050 0b35ee1acf4c96e56267a60d9b16a03a 314 PANTHER PTHR22935:SF10 3 298 5.9E-45 T 21-04-2016 HSISS4_RS08050 0b35ee1acf4c96e56267a60d9b16a03a 314 PANTHER PTHR22935 3 298 5.9E-45 T 21-04-2016 HSISS4_RS08050 0b35ee1acf4c96e56267a60d9b16a03a 314 Pfam PF00144 Beta-lactamase 20 299 2.7E-44 T 21-04-2016 IPR001466 Beta-lactamase-related HSISS4_RS08050 0b35ee1acf4c96e56267a60d9b16a03a 314 Gene3D G3DSA:3.40.710.10 6 293 8.7E-54 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS08050 0b35ee1acf4c96e56267a60d9b16a03a 314 SUPERFAMILY SSF56601 5 298 4.69E-61 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS03175 25c50bcb86c2eb7f65a44cfc650b90fc 279 Pfam PF14133 Domain of unknown function (DUF4300) 37 276 8.1E-83 T 21-04-2016 IPR025389 Protein of unknown function DUF4300 HSISS4_RS08995 dcbc8fe5264a3dd8bf1d02c33b148059 104 SUPERFAMILY SSF52833 3 103 9.43E-25 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08995 dcbc8fe5264a3dd8bf1d02c33b148059 104 PANTHER PTHR10438:SF301 7 104 1.6E-39 T 21-04-2016 HSISS4_RS08995 dcbc8fe5264a3dd8bf1d02c33b148059 104 PANTHER PTHR10438 7 104 1.6E-39 T 21-04-2016 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 HSISS4_RS08995 dcbc8fe5264a3dd8bf1d02c33b148059 104 Gene3D G3DSA:3.40.30.10 8 103 1.0E-20 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08995 dcbc8fe5264a3dd8bf1d02c33b148059 104 Pfam PF00085 Thioredoxin 9 102 9.2E-16 T 21-04-2016 IPR013766 Thioredoxin domain GO:0045454 HSISS4_RS09040 00d8a541c171f2c016c64ab37aede8f0 318 SUPERFAMILY SSF53335 49 298 2.84E-33 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS09040 00d8a541c171f2c016c64ab37aede8f0 318 PANTHER PTHR41313 2 317 5.5E-102 T 21-04-2016 HSISS4_RS09040 00d8a541c171f2c016c64ab37aede8f0 318 Gene3D G3DSA:3.40.50.150 89 312 1.3E-19 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS09040 00d8a541c171f2c016c64ab37aede8f0 318 PIRSF PIRSF026567 1 317 7.8E-104 T 21-04-2016 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted HSISS4_RS09040 00d8a541c171f2c016c64ab37aede8f0 318 Pfam PF02384 N-6 DNA Methylase 69 297 1.5E-7 T 21-04-2016 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 HSISS4_RS03790 bda49a11ff9df1ed5e21fc0ab08d4547 146 Pfam PF04138 GtrA-like protein 15 141 2.0E-22 T 21-04-2016 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 HSISS4_RS03790 bda49a11ff9df1ed5e21fc0ab08d4547 146 PANTHER PTHR38459 1 146 8.6E-15 T 21-04-2016 HSISS4_RS05035 4bf5423d9a8a1dfb110edb813f1f1cc6 126 Pfam PF03750 Protein of unknown function (DUF310) 7 125 1.6E-21 T 21-04-2016 IPR010149 CRISPR-associated protein, TM1810 C-terminal HSISS4_RS05035 4bf5423d9a8a1dfb110edb813f1f1cc6 126 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 35 124 1.9E-18 T 21-04-2016 IPR010149 CRISPR-associated protein, TM1810 C-terminal HSISS4_RS04165 be50d89f4c95fb193e80b1d3ee6db1e4 73 Pfam PF15507 Domain of unknown function (DUF4649) 2 69 3.3E-32 T 21-04-2016 IPR027879 Protein of unknown function DUF4649 HSISS4_RS05550 018d89c4b9033f64be714eb8392c5ac6 636 SUPERFAMILY SSF55797 540 635 3.4E-7 T 21-04-2016 IPR014044 CAP domain HSISS4_RS02510 5093fbcdb585a5b8831ff1786209f1a2 197 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 30 97 4.3E-15 T 21-04-2016 IPR025159 Transcriptional regulator, AbiEi antitoxin HSISS4_RS04935 cab35d5e84df26d027443829a4835c41 77 SUPERFAMILY SSF140683 4 76 7.45E-20 T 21-04-2016 HSISS4_RS04935 cab35d5e84df26d027443829a4835c41 77 Gene3D G3DSA:1.10.3910.10 2 76 1.9E-30 T 21-04-2016 IPR015077 Domain of unknown function DUF1858 HSISS4_RS04935 cab35d5e84df26d027443829a4835c41 77 Pfam PF08984 Domain of unknown function (DUF1858) 6 63 2.4E-17 T 21-04-2016 IPR015077 Domain of unknown function DUF1858 HSISS4_RS08650 9c56c4db4208cd6a2e77d2eb5e141c31 143 Pfam PF13380 CoA binding domain 21 138 4.9E-32 T 21-04-2016 IPR003781 CoA-binding GO:0048037 HSISS4_RS08650 9c56c4db4208cd6a2e77d2eb5e141c31 143 SMART SM00881 17 111 1.7E-17 T 21-04-2016 IPR003781 CoA-binding GO:0048037 HSISS4_RS08650 9c56c4db4208cd6a2e77d2eb5e141c31 143 SUPERFAMILY SSF51735 13 141 1.18E-36 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS08650 9c56c4db4208cd6a2e77d2eb5e141c31 143 PANTHER PTHR33303 11 142 4.8E-40 T 21-04-2016 HSISS4_RS08650 9c56c4db4208cd6a2e77d2eb5e141c31 143 Gene3D G3DSA:3.40.50.720 10 142 1.1E-43 T 21-04-2016 IPR016040 NAD(P)-binding domain HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 PANTHER PTHR34184:SF1 1 300 6.2E-114 T 21-04-2016 HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 Pfam PF03773 Predicted permease 13 298 2.8E-68 T 21-04-2016 IPR005524 Predicted permease DUF318 HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 PRINTS PR00173 Glutamate-aspartate symporter signature 50 70 3.4E-6 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 PRINTS PR00173 Glutamate-aspartate symporter signature 278 297 3.4E-6 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 PRINTS PR00173 Glutamate-aspartate symporter signature 120 145 3.4E-6 T 21-04-2016 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 Reactome: REACT_15518|Reactome: REACT_19419 HSISS4_RS03310 25ca09fb792017e07854f5954eec8830 300 PANTHER PTHR34184 1 300 6.2E-114 T 21-04-2016 HSISS4_RS09500 345823b4320f432a10b50d75eed2cf3d 241 Pfam PF13751 Transposase DDE domain 83 201 1.1E-19 T 21-04-2016 IPR025668 Transposase DDE domain HSISS4_RS09500 345823b4320f432a10b50d75eed2cf3d 241 PANTHER PTHR33408 28 240 1.1E-18 T 21-04-2016 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 PANTHER PTHR34296 3 349 3.0E-122 T 21-04-2016 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 Gene3D G3DSA:3.40.50.2300 161 324 5.6E-55 T 21-04-2016 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 PANTHER PTHR34296:SF2 3 349 3.0E-122 T 21-04-2016 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 Pfam PF02608 Basic membrane protein 40 344 1.5E-75 T 21-04-2016 IPR003760 Basic membrane lipoprotein GO:0005886 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 Gene3D G3DSA:3.40.50.2300 34 160 1.7E-48 T 21-04-2016 HSISS4_RS05630 c00c5d1ca79e3d100cce335b6df9f5f3 356 SUPERFAMILY SSF53822 53 264 3.64E-23 T 21-04-2016 IPR028082 Periplasmic binding protein-like I HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 Pfam PF09211 Domain of unknown function (DUF1958) 320 381 7.2E-23 T 21-04-2016 IPR015294 Penicillin-binding protein 4, C-terminal domain HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 Gene3D G3DSA:2.30.140.20 318 383 9.0E-27 T 21-04-2016 IPR015294 Penicillin-binding protein 4, C-terminal domain HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PANTHER PTHR21581:SF11 195 341 9.1E-66 T 21-04-2016 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PANTHER PTHR21581 195 341 9.1E-66 T 21-04-2016 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 SUPERFAMILY SSF56601 2 318 1.77E-63 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 SUPERFAMILY SSF69189 319 383 1.65E-18 T 21-04-2016 IPR015956 Penicillin-binding protein-associated GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471|UniPathway: UPA00219 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PANTHER PTHR21581:SF11 45 179 9.1E-66 T 21-04-2016 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 Gene3D G3DSA:3.40.710.10 10 316 1.8E-70 T 21-04-2016 IPR012338 Beta-lactamase/transpeptidase-like HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 70 81 1.4E-9 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 127 144 1.4E-9 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 155 168 1.4E-9 T 21-04-2016 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 41 291 3.2E-45 T 21-04-2016 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 HSISS4_RS04715 e9fde30f1192c2efe33bae44fbd4838e 448 PANTHER PTHR21581 45 179 9.1E-66 T 21-04-2016 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 ProSitePatterns PS00638 P-II protein C-terminal region signature. 84 97 - T 21-04-2016 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 PANTHER PTHR30115 1 113 1.4E-44 T 21-04-2016 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 SMART SM00938 4 106 5.9E-44 T 21-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 Pfam PF00543 Nitrogen regulatory protein P-II 4 106 4.4E-36 T 21-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 SUPERFAMILY SSF54913 1 113 2.22E-36 T 21-04-2016 IPR011322 Nitrogen regulatory PII-like, alpha/beta HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 PRINTS PR00340 P-II protein signature 84 104 6.3E-25 T 21-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 PRINTS PR00340 P-II protein signature 2 17 6.3E-25 T 21-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 PRINTS PR00340 P-II protein signature 53 76 6.3E-25 T 21-04-2016 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 HSISS4_RS02335 268652de4c143df441b9f9ad49fb9bc6 113 Gene3D G3DSA:3.30.70.120 1 113 7.0E-41 T 21-04-2016 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 SUPERFAMILY SSF55120 60 231 1.12E-38 T 21-04-2016 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 100 114 - T 21-04-2016 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 PANTHER PTHR21600 1 230 1.2E-59 T 21-04-2016 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 Pfam PF01479 S4 domain 1 42 5.8E-9 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 PANTHER PTHR21600:SF19 1 230 1.2E-59 T 21-04-2016 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 SMART SM00363 1 64 8.5E-7 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 Pfam PF00849 RNA pseudouridylate synthase 62 195 2.9E-19 T 21-04-2016 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 SUPERFAMILY SSF55174 1 90 2.65E-14 T 21-04-2016 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 228 6.4E-41 T 21-04-2016 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 HSISS4_RS02555 85cf953a99b520232236e8e43e013b7c 239 Gene3D G3DSA:3.10.290.10 1 64 1.5E-15 T 21-04-2016 IPR002942 RNA-binding S4 domain GO:0003723 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 SUPERFAMILY SSF75217 1 157 7.85E-59 T 21-04-2016 IPR029028 Alpha/beta knot methyltransferases HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 Pfam PF02590 Predicted SPOUT methyltransferase 1 158 6.4E-58 T 21-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 PIRSF PIRSF004505 1 159 1.0E-51 T 21-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 PANTHER PTHR33603:SF1 1 159 3.4E-66 T 21-04-2016 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 Gene3D G3DSA:3.40.1280.10 1 159 1.0E-61 T 21-04-2016 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 159 30.5 T 21-04-2016 IPR003742 SPOUT methyltransferase, predicted GO:0005737|GO:0006364|GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 159 1.3E-57 T 21-04-2016 IPR016051 Ribosomal RNA large subunit methyltransferase H GO:0005737|GO:0008168|GO:0031167 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 HSISS4_RS09740 08c962ac5d15b9b1fa32a12ca302a574 159 PANTHER PTHR33603 1 159 3.4E-66 T 21-04-2016 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 Gene3D G3DSA:1.20.1250.20 219 398 2.2E-29 T 21-04-2016 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 Gene3D G3DSA:1.20.1250.20 12 194 6.1E-36 T 21-04-2016 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 SUPERFAMILY SSF103473 10 396 6.71E-68 T 21-04-2016 IPR020846 Major facilitator superfamily domain HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 PANTHER PTHR23504:SF14 2 398 3.7E-87 T 21-04-2016 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 PANTHER PTHR23504 2 398 3.7E-87 T 21-04-2016 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 Pfam PF07690 Major Facilitator Superfamily 19 243 1.4E-32 T 21-04-2016 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 HSISS4_RS02930 20499435de05a1bd194f89dc0bcd6a1f 407 Pfam PF00083 Sugar (and other) transporter 255 389 6.6E-10 T 21-04-2016 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 HSISS4_RS01530 c97158c825fbb4d80c773c61d8bd173b 173 Gene3D G3DSA:3.40.630.30 4 171 8.0E-40 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01530 c97158c825fbb4d80c773c61d8bd173b 173 SUPERFAMILY SSF55729 5 172 6.75E-31 T 21-04-2016 IPR016181 Acyl-CoA N-acyltransferase HSISS4_RS01530 c97158c825fbb4d80c773c61d8bd173b 173 Pfam PF00583 Acetyltransferase (GNAT) family 66 145 2.6E-16 T 21-04-2016 IPR000182 GNAT domain GO:0008080 HSISS4_RS01530 c97158c825fbb4d80c773c61d8bd173b 173 PANTHER PTHR23091 5 173 5.4E-23 T 21-04-2016 HSISS4_RS08660 9e6d8d6e6657f028a09ae0d3e91b5eb0 260 SMART SM00506 84 224 7.8E-29 T 21-04-2016 IPR002589 Macro domain HSISS4_RS08660 9e6d8d6e6657f028a09ae0d3e91b5eb0 260 SUPERFAMILY SSF52949 78 259 6.39E-56 T 21-04-2016 HSISS4_RS08660 9e6d8d6e6657f028a09ae0d3e91b5eb0 260 Gene3D G3DSA:3.40.220.10 80 259 4.6E-61 T 21-04-2016 HSISS4_RS08660 9e6d8d6e6657f028a09ae0d3e91b5eb0 260 PANTHER PTHR11106 24 260 4.5E-72 T 21-04-2016 HSISS4_RS08660 9e6d8d6e6657f028a09ae0d3e91b5eb0 260 Pfam PF01661 Macro domain 101 224 3.4E-33 T 21-04-2016 IPR002589 Macro domain HSISS4_RS05745 9cc6876c12a3335977139bc7940da0eb 43 Pfam PF12459 D-Ala-teichoic acid biosynthesis protein 1 43 9.1E-21 T 21-04-2016 IPR021008 Protein of unknown function DUF3687 HSISS4_RS03380 752a77039dc63bb70118746713f3bd48 70 Pfam PF02229 Transcriptional Coactivator p15 (PC4) 19 66 6.3E-11 T 21-04-2016 IPR003173 Transcriptional coactivator p15 (PC4) GO:0003677|GO:0003713|GO:0006355 HSISS4_RS03380 752a77039dc63bb70118746713f3bd48 70 PIRSF PIRSF037246 1 70 1.2E-37 T 21-04-2016 IPR017154 Uncharacterised conserved protein UCP037246 HSISS4_RS08990 b9b1c1dfad9037027772bbc0ee26b48f 174 Pfam PF15655 NTF2 fold immunity protein 52 170 1.7E-6 T 21-04-2016 IPR028049 NTF2 fold immunity protein HSISS4_RS03535 bfb1bd1ac51bf2e6da3edcc697aea3be 299 Pfam PF01435 Peptidase family M48 77 299 8.8E-37 T 21-04-2016 IPR001915 Peptidase M48 GO:0004222|GO:0006508 HSISS4_RS03535 bfb1bd1ac51bf2e6da3edcc697aea3be 299 Gene3D G3DSA:3.30.2010.10 70 159 2.3E-33 T 21-04-2016 HSISS4_RS03535 bfb1bd1ac51bf2e6da3edcc697aea3be 299 Hamap MF_00188 Protease HtpX [htpX]. 10 299 27.785 T 21-04-2016 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 HSISS4_RS03535 bfb1bd1ac51bf2e6da3edcc697aea3be 299 PANTHER PTHR10120 16 299 5.2E-97 T 21-04-2016 HSISS4_RS03535 bfb1bd1ac51bf2e6da3edcc697aea3be 299 PANTHER PTHR10120:SF19 16 299 5.2E-97 T 21-04-2016 HSISS4_RS01610 3a3f8ae365c9141c41b2576ef0e7e7ac 971 Pfam PF02435 Levansucrase/Invertase 231 685 1.0E-120 T 21-04-2016 IPR003469 Glycoside hydrolase, family 68 GO:0009758|GO:0050053 HSISS4_RS01610 3a3f8ae365c9141c41b2576ef0e7e7ac 971 Pfam PF04650 YSIRK type signal peptide 20 45 4.7E-5 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS01610 3a3f8ae365c9141c41b2576ef0e7e7ac 971 Gene3D G3DSA:2.115.10.20 226 682 3.6E-145 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS01610 3a3f8ae365c9141c41b2576ef0e7e7ac 971 SUPERFAMILY SSF75005 231 688 1.57E-81 T 21-04-2016 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain HSISS4_RS01610 3a3f8ae365c9141c41b2576ef0e7e7ac 971 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 20 54 1.5E-8 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS02475 ecbd6c7d38ba2e846f1af54519d98b04 251 PANTHER PTHR36112:SF2 1 251 2.0E-40 T 21-04-2016 HSISS4_RS02475 ecbd6c7d38ba2e846f1af54519d98b04 251 PANTHER PTHR36112 1 251 2.0E-40 T 21-04-2016 HSISS4_RS02475 ecbd6c7d38ba2e846f1af54519d98b04 251 Pfam PF04445 Putative SAM-dependent methyltransferase 84 219 3.8E-17 T 21-04-2016 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 HSISS4_RS02475 ecbd6c7d38ba2e846f1af54519d98b04 251 Gene3D G3DSA:3.40.50.150 65 247 3.2E-43 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS02475 ecbd6c7d38ba2e846f1af54519d98b04 251 SUPERFAMILY SSF53335 2 244 1.61E-46 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS02550 b25724630c45933892db9a3d678488b2 227 Pfam PF01988 VIT family 13 220 1.6E-46 T 21-04-2016 IPR008217 Ccc1 family HSISS4_RS02550 b25724630c45933892db9a3d678488b2 227 PANTHER PTHR31851 2 223 8.3E-54 T 21-04-2016 HSISS4_RS01780 cb128e7f1635bc87b8a947f739ba614a 263 PANTHER PTHR11941:SF76 3 260 3.4E-96 T 21-04-2016 HSISS4_RS01780 cb128e7f1635bc87b8a947f739ba614a 263 PANTHER PTHR11941 3 260 3.4E-96 T 21-04-2016 HSISS4_RS01780 cb128e7f1635bc87b8a947f739ba614a 263 SUPERFAMILY SSF52096 1 262 7.76E-76 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS01780 cb128e7f1635bc87b8a947f739ba614a 263 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 262 1.8E-54 T 21-04-2016 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 HSISS4_RS01780 cb128e7f1635bc87b8a947f739ba614a 263 Gene3D G3DSA:3.90.226.10 1 261 1.8E-75 T 21-04-2016 IPR029045 ClpP/crotonase-like domain HSISS4_RS09385 a4185c2c44e52ec03b68ea3119a433c3 168 PANTHER PTHR37816 1 167 4.2E-37 T 21-04-2016 HSISS4_RS09385 a4185c2c44e52ec03b68ea3119a433c3 168 SUPERFAMILY SSF52540 2 167 6.46E-15 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09385 a4185c2c44e52ec03b68ea3119a433c3 168 Gene3D G3DSA:3.40.50.300 2 145 2.2E-12 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS09385 a4185c2c44e52ec03b68ea3119a433c3 168 PANTHER PTHR37816:SF1 1 167 4.2E-37 T 21-04-2016 HSISS4_RS06340 0da5aa1972f7a6f702983439e43ada22 228 Pfam PF06912 Protein of unknown function (DUF1275) 17 212 4.3E-24 T 21-04-2016 IPR010699 Protein of unknown function DUF1275 HSISS4_RS04460 50b56c053bb5e2dcd5e8906a62d8d05d 392 PANTHER PTHR21716 13 29 9.4E-72 T 21-04-2016 IPR002549 Transmembrane protein TqsA-like HSISS4_RS04460 50b56c053bb5e2dcd5e8906a62d8d05d 392 PANTHER PTHR21716 45 372 9.4E-72 T 21-04-2016 IPR002549 Transmembrane protein TqsA-like HSISS4_RS04460 50b56c053bb5e2dcd5e8906a62d8d05d 392 Pfam PF01594 Domain of unknown function DUF20 35 366 3.6E-69 T 21-04-2016 IPR002549 Transmembrane protein TqsA-like HSISS4_RS02700 ee8221f53b246ff091706b31424f6cda 149 PANTHER PTHR40056:SF1 1 125 7.2E-23 T 21-04-2016 HSISS4_RS02700 ee8221f53b246ff091706b31424f6cda 149 PANTHER PTHR40056 1 125 7.2E-23 T 21-04-2016 HSISS4_RS02700 ee8221f53b246ff091706b31424f6cda 149 Pfam PF08876 Domain of unknown function (DUF1836) 8 107 3.0E-33 T 21-04-2016 IPR014975 Protein of unknown function DUF1836 HSISS4_RS03480 9cc29e6c8f4408d998a403499206fa2a 380 Pfam PF14253 Bacteriophage abortive infection AbiH 5 322 1.0E-37 T 21-04-2016 IPR025935 Bacteriophage abortive infection AbiH HSISS4_RS06470 96ac70baf4281ba39e750dfe5510d865 421 Pfam PF06738 Putative threonine/serine exporter 19 258 2.3E-48 T 21-04-2016 IPR010619 Putative threonine/serine exporter HSISS4_RS06470 96ac70baf4281ba39e750dfe5510d865 421 PANTHER PTHR31082 20 410 2.8E-33 T 21-04-2016 HSISS4_RS06470 96ac70baf4281ba39e750dfe5510d865 421 Pfam PF12821 Threonine/Serine exporter, ThrE 282 408 1.5E-22 T 21-04-2016 IPR024528 Threonine/Serine exporter, ThrE HSISS4_RS03305 359629b41f029c0b7f4790d952accdab 271 PANTHER PTHR40047 1 271 2.3E-73 T 21-04-2016 HSISS4_RS03305 359629b41f029c0b7f4790d952accdab 271 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 266 2.3E-54 T 21-04-2016 IPR015402 Protein of unknown function DUF1980 HSISS4_RS03305 359629b41f029c0b7f4790d952accdab 271 Pfam PF09323 Domain of unknown function (DUF1980) 1 178 2.2E-63 T 21-04-2016 IPR015402 Protein of unknown function DUF1980 HSISS4_RS05890 33a6252e11ec399a426a077733bebba0 176 Pfam PF16729 Domain of unknown function (DUF5067) 22 147 1.4E-20 T 21-04-2016 IPR031989 Domain of unknown function DUF5067 HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 SMART SM00382 28 220 4.5E-11 T 21-04-2016 IPR003593 AAA+ ATPase domain HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 Gene3D G3DSA:3.40.50.300 3 233 1.6E-51 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 PANTHER PTHR24220:SF383 5 250 1.5E-87 T 21-04-2016 HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 SUPERFAMILY SSF52540 3 232 2.28E-48 T 21-04-2016 IPR027417 P-loop containing nucleoside triphosphate hydrolase HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 Pfam PF00005 ABC transporter 19 169 2.7E-27 T 21-04-2016 IPR003439 ABC transporter-like GO:0005524|GO:0016887 HSISS4_RS07945 b42223ca3e2e465ac7e95b0f19d8badd 260 PANTHER PTHR24220 5 250 1.5E-87 T 21-04-2016 HSISS4_RS04330 330781e039e8119716d8be1f96b80e48 293 SMART SM00892 116 292 4.7E-28 T 21-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 HSISS4_RS04330 330781e039e8119716d8be1f96b80e48 293 Pfam PF01223 DNA/RNA non-specific endonuclease 99 266 5.6E-17 T 21-04-2016 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 HSISS4_RS04330 330781e039e8119716d8be1f96b80e48 293 ProSitePatterns PS01070 DNA/RNA non-specific endonucleases active site. 178 186 - T 21-04-2016 IPR018524 DNA/RNA non-specific endonuclease, active site GO:0003676|GO:0016787|GO:0046872 HSISS4_RS03970 b8356cdbbf8dffbd3e9e78187419f00c 76 Pfam PF06570 Protein of unknown function (DUF1129) 7 68 1.7E-17 T 21-04-2016 IPR009214 Protein of unknown function DUF1129 HSISS4_RS03565 2e65d140604626aa4584ff60cf289663 131 Pfam PF14478 Domain of unknown function (DUF4430) 63 128 5.7E-19 T 21-04-2016 IPR027954 Domain of unknown function DUF4430 HSISS4_RS04745 a49f49c2d87f0eff8994bc0d838704ec 418 PANTHER PTHR40448 5 412 1.0E-12 T 21-04-2016 HSISS4_RS06695 36c67d54a7698d4922afd6d46440ae14 1700 TIGRFAM TIGR03715 KxYKxGKxW: KxYKxGKxW signal peptide 17 38 8.6E-6 T 21-04-2016 IPR022263 KxYKxGKxW signal peptide HSISS4_RS06695 36c67d54a7698d4922afd6d46440ae14 1700 TIGRFAM TIGR04224 ser_adhes_Nterm: serine-rich repeat adhesion glycoprotein 36 84 1.9E-17 T 21-04-2016 IPR026465 Serine-rich repeat adhesion glycoprotein HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 SUPERFAMILY SSF52833 3 158 1.69E-59 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 21-04-2016 IPR029759 Glutathione peroxidase active site HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 Pfam PF00255 Glutathione peroxidase 4 111 3.2E-39 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 21-04-2016 IPR029760 Glutathione peroxidase conserved site HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 PRINTS PR01011 Glutathione peroxidase family signature 57 73 1.0E-17 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.0E-17 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 PRINTS PR01011 Glutathione peroxidase family signature 22 39 1.0E-17 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 Gene3D G3DSA:3.40.30.10 3 159 5.7E-71 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 PANTHER PTHR11592 1 158 2.7E-82 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS06240 24dba5ea8cfe551c8ddb6654a4311c85 160 PIRSF PIRSF000303 1 160 6.0E-64 T 21-04-2016 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 HSISS4_RS03730 1858fddac592034e51aef0614d578064 387 Pfam PF13535 ATP-grasp domain 168 286 7.5E-7 T 21-04-2016 HSISS4_RS03730 1858fddac592034e51aef0614d578064 387 SUPERFAMILY SSF56059 87 320 2.47E-32 T 21-04-2016 HSISS4_RS03730 1858fddac592034e51aef0614d578064 387 Gene3D G3DSA:3.30.470.20 107 346 2.0E-28 T 21-04-2016 IPR013816 ATP-grasp fold, subdomain 2 GO:0005524 HSISS4_RS04430 72522af19273a3396ea8eabb3a7e7269 285 TIGRFAM TIGR03729 acc_ester: putative phosphoesterase 3 226 1.9E-80 T 21-04-2016 IPR022302 Phosphoesterase, putative HSISS4_RS04430 72522af19273a3396ea8eabb3a7e7269 285 SUPERFAMILY SSF56300 3 109 7.16E-22 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS04430 72522af19273a3396ea8eabb3a7e7269 285 SUPERFAMILY SSF56300 140 231 7.16E-22 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS04430 72522af19273a3396ea8eabb3a7e7269 285 Pfam PF00149 Calcineurin-like phosphoesterase 3 207 1.4E-10 T 21-04-2016 IPR004843 Calcineurin-like phosphoesterase domain, apaH type GO:0016787 HSISS4_RS04430 72522af19273a3396ea8eabb3a7e7269 285 Gene3D G3DSA:3.60.21.10 2 229 4.2E-15 T 21-04-2016 IPR029052 Metallo-dependent phosphatase-like HSISS4_RS07115 cb9175e25c33c76ac19a252d304e5bef 229 Gene3D G3DSA:3.90.550.10 6 163 2.7E-16 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07115 cb9175e25c33c76ac19a252d304e5bef 229 PANTHER PTHR10859:SF84 1 221 3.4E-42 T 21-04-2016 HSISS4_RS07115 cb9175e25c33c76ac19a252d304e5bef 229 PANTHER PTHR10859 1 221 3.4E-42 T 21-04-2016 HSISS4_RS07115 cb9175e25c33c76ac19a252d304e5bef 229 SUPERFAMILY SSF53448 5 220 7.74E-38 T 21-04-2016 IPR029044 Nucleotide-diphospho-sugar transferases HSISS4_RS07115 cb9175e25c33c76ac19a252d304e5bef 229 Pfam PF00535 Glycosyl transferase family 2 6 162 3.6E-24 T 21-04-2016 IPR001173 Glycosyltransferase 2-like HSISS4_RS03450 c17ecf36269bd7fef263f6892810e3a2 129 Gene3D G3DSA:3.30.450.20 2 111 1.0E-6 T 21-04-2016 HSISS4_RS08290 690de17d6a666478f6d6c6191e8b97e5 70 Gene3D G3DSA:1.10.260.40 2 69 2.8E-14 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS08290 690de17d6a666478f6d6c6191e8b97e5 70 PANTHER PTHR37301 1 68 2.3E-34 T 21-04-2016 HSISS4_RS08290 690de17d6a666478f6d6c6191e8b97e5 70 SUPERFAMILY SSF47413 1 68 2.87E-16 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS08290 690de17d6a666478f6d6c6191e8b97e5 70 SMART SM00530 5 61 4.7E-4 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS08290 690de17d6a666478f6d6c6191e8b97e5 70 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 5 65 1.6E-20 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS05980 5f18fe23483f7094ebec97cce98ffcea 93 Pfam PF01446 Replication protein 19 78 2.8E-11 T 21-04-2016 IPR000989 Replication protein GO:0003677|GO:0005727|GO:0006260 HSISS4_RS01275 d1e5237f3d09005d1162bc6d380667d8 185 Pfam PF12822 Protein of unknown function (DUF3816) 5 175 8.9E-23 T 21-04-2016 IPR024529 ECF transporter, substrate-specific component GO:0005215 HSISS4_RS01275 d1e5237f3d09005d1162bc6d380667d8 185 PIRSF PIRSF037778 1 185 2.8E-59 T 21-04-2016 IPR025720 ECF transporter, Riboflavin transporter RibU GO:0005886|GO:0032217|GO:0032218 HSISS4_RS01275 d1e5237f3d09005d1162bc6d380667d8 185 PANTHER PTHR38438 1 182 3.0E-52 T 21-04-2016 HSISS4_RS01275 d1e5237f3d09005d1162bc6d380667d8 185 PANTHER PTHR38438:SF1 1 182 3.0E-52 T 21-04-2016 HSISS4_RS09635 5f44b10bb83bb524cf282079564b421f 232 SUPERFAMILY SSF53955 161 223 4.3E-10 T 21-04-2016 IPR023346 Lysozyme-like domain HSISS4_RS09635 5f44b10bb83bb524cf282079564b421f 232 Gene3D G3DSA:1.10.530.10 162 208 4.7E-8 T 21-04-2016 HSISS4_RS09635 5f44b10bb83bb524cf282079564b421f 232 Pfam PF01464 Transglycosylase SLT domain 163 205 1.8E-5 T 21-04-2016 IPR008258 Transglycosylase SLT domain 1 HSISS4_RS06705 2b515863935ff0b4e60eb304e2bede82 249 Pfam PF06458 MucBP domain 2 66 2.3E-4 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06705 2b515863935ff0b4e60eb304e2bede82 249 Pfam PF06458 MucBP domain 77 166 5.6E-10 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06705 2b515863935ff0b4e60eb304e2bede82 249 Pfam PF00746 Gram positive anchor 207 244 8.4E-9 T 21-04-2016 IPR019948 Gram-positive anchor HSISS4_RS06705 2b515863935ff0b4e60eb304e2bede82 249 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 213 246 7.9E-7 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06705 2b515863935ff0b4e60eb304e2bede82 249 Gene3D G3DSA:3.10.20.320 73 172 5.1E-9 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS03295 3c6371b58bf7ae2abbbcf6359dfa2e2d 204 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 2 156 1.6E-5 T 21-04-2016 IPR018672 Protein of unknown function DUF2140 HSISS4_RS06675 e071df6becafe9418182446687b6934c 249 SUPERFAMILY SSF56281 3 240 5.32E-17 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS06675 e071df6becafe9418182446687b6934c 249 PANTHER PTHR15032 56 249 2.5E-19 T 21-04-2016 HSISS4_RS06675 e071df6becafe9418182446687b6934c 249 Gene3D G3DSA:3.60.15.10 3 248 4.3E-28 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS06675 e071df6becafe9418182446687b6934c 249 Pfam PF12706 Beta-lactamase superfamily domain 55 220 1.1E-12 T 21-04-2016 IPR001279 Metallo-beta-lactamase HSISS4_RS04130 4172276f42b3682d7699ca4be1d9b8d5 93 PANTHER PTHR41336 1 92 1.0E-15 T 21-04-2016 HSISS4_RS04130 4172276f42b3682d7699ca4be1d9b8d5 93 Pfam PF06961 Protein of unknown function (DUF1294) 15 69 8.5E-21 T 21-04-2016 IPR010718 Protein of unknown function DUF1294 HSISS4_RS05080 6d40bbec79f270594c49714ad6a9591f 266 Pfam PF05857 TraX protein 12 262 5.1E-24 T 21-04-2016 IPR008875 TraX HSISS4_RS08015 bbf0edaf878603a6d5b0e61776529160 296 Gene3D G3DSA:3.30.70.80 78 118 2.0E-4 T 21-04-2016 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 HSISS4_RS08165 ed19679938940f66a6a14d0493903a50 153 Pfam PF02706 Chain length determinant protein 2 73 1.8E-7 T 21-04-2016 IPR003856 Lipopolysaccharide biosynthesis GO:0009103|GO:0016020 HSISS4_RS09420 52a4cc0ef3eac683580585b669ae9d8e 101 PANTHER PTHR40066:SF1 1 100 9.1E-27 T 21-04-2016 HSISS4_RS09420 52a4cc0ef3eac683580585b669ae9d8e 101 Hamap MF_01448 UPF0473 protein . 10 100 22.888 T 21-04-2016 IPR009711 Uncharacterised protein family UPF0473 HSISS4_RS09420 52a4cc0ef3eac683580585b669ae9d8e 101 PANTHER PTHR40066 1 100 9.1E-27 T 21-04-2016 HSISS4_RS09420 52a4cc0ef3eac683580585b669ae9d8e 101 Pfam PF06949 Protein of unknown function (DUF1292) 19 99 3.0E-15 T 21-04-2016 IPR009711 Uncharacterised protein family UPF0473 HSISS4_RS06780 8634cc572d92001ec9a134f87bdcb229 1214 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 1179 1212 3.4E-4 T 21-04-2016 IPR019931 LPXTG cell wall anchor domain HSISS4_RS06780 8634cc572d92001ec9a134f87bdcb229 1214 Pfam PF04650 YSIRK type signal peptide 6 30 3.8E-10 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS06780 8634cc572d92001ec9a134f87bdcb229 1214 TIGRFAM TIGR01168 YSIRK_signal: gram-positive signal peptide, YSIRK family 1 40 2.1E-12 T 21-04-2016 IPR005877 YSIRK Gram-positive signal peptide GO:0016020 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 TIGRFAM TIGR02113 coaC_strep: phosphopantothenoylcysteine decarboxylase 3 178 1.7E-92 T 21-04-2016 IPR011847 Phosphopantothenoylcysteine decarboxylase KEGG: 00770+4.1.1.36|UniPathway: UPA00241 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 PANTHER PTHR14359 3 179 1.2E-76 T 21-04-2016 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 SUPERFAMILY SSF52507 2 178 1.31E-59 T 21-04-2016 IPR003382 Flavoprotein GO:0003824 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 PANTHER PTHR14359:SF20 3 179 1.2E-76 T 21-04-2016 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 Pfam PF02441 Flavoprotein 3 133 7.8E-40 T 21-04-2016 IPR003382 Flavoprotein GO:0003824 HSISS4_RS05685 1791977485bf822008de47eafbaefd2c 181 Gene3D G3DSA:3.40.50.1950 3 179 3.3E-66 T 21-04-2016 IPR003382 Flavoprotein GO:0003824 HSISS4_RS02105 57b00b0115119f62975b3fb1117e3a5d 380 SUPERFAMILY SSF109998 110 235 2.98E-13 T 21-04-2016 IPR027304 Trigger factor/SurA domain HSISS4_RS02105 57b00b0115119f62975b3fb1117e3a5d 380 Hamap MF_01145 Foldase protein PrsA [prsA]. 75 365 15.839 T 21-04-2016 IPR023059 Foldase protein PrsA GO:0003755 HSISS4_RS02105 57b00b0115119f62975b3fb1117e3a5d 380 Pfam PF13145 PPIC-type PPIASE domain 203 320 8.8E-11 T 21-04-2016 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0016853 HSISS4_RS02810 278a0f323835d7ff443b8bbc5ea9677a 206 Pfam PF12978 Domain of Unknown Function with PDB structure (DUF3862) 45 203 6.2E-51 T 21-04-2016 IPR024418 Protein of unknown function DUF3862 HSISS4_RS01260 fe5106778b2dc39efdad3e5175ca5e09 479 Pfam PF02386 Cation transport protein 45 472 3.0E-48 T 21-04-2016 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 HSISS4_RS01260 fe5106778b2dc39efdad3e5175ca5e09 479 PANTHER PTHR32024:SF2 1 478 1.5E-184 T 21-04-2016 HSISS4_RS01260 fe5106778b2dc39efdad3e5175ca5e09 479 PANTHER PTHR32024 1 478 1.5E-184 T 21-04-2016 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 SUPERFAMILY SSF47413 3 63 4.56E-11 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 TIGRFAM TIGR01716 RGG_Cterm: transcriptional activator, Rgg/GadR/MutR family, C-terminal domain 63 284 3.0E-50 T 21-04-2016 IPR010057 Transcription activator MutR, C-terminal HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 Gene3D G3DSA:1.10.260.40 1 67 2.1E-12 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 Pfam PF12844 Helix-turn-helix domain 5 63 8.4E-9 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 SMART SM00530 7 61 9.2E-10 T 21-04-2016 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 PANTHER PTHR37038:SF1 2 286 4.3E-59 T 21-04-2016 HSISS4_RS07560 ce367136aad4f3d02328e596d35163c1 287 PANTHER PTHR37038 2 286 4.3E-59 T 21-04-2016 HSISS4_RS02745 455c53a37baa7c15bb04321d87236ae5 84 SUPERFAMILY SSF140121 1 77 9.15E-40 T 21-04-2016 HSISS4_RS02745 455c53a37baa7c15bb04321d87236ae5 84 Pfam PF08930 Domain of unknown function (DUF1912) 1 84 2.2E-47 T 21-04-2016 IPR015026 Protein of unknown function DUF1912 HSISS4_RS02745 455c53a37baa7c15bb04321d87236ae5 84 Gene3D G3DSA:1.20.58.90 1 84 2.7E-46 T 21-04-2016 HSISS4_RS05780 9761ed2f2bc2683df92ce4d33624eea7 325 Pfam PF04245 37-kD nucleoid-associated bacterial protein 10 321 2.3E-34 T 21-04-2016 IPR007358 Nucleoid-associated protein NdpA GO:0009295 HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 PANTHER PTHR12526 270 501 1.4E-23 T 21-04-2016 HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 Hamap MF_01472 Glycosyltransferase Gtf1 [gtf1]. 2 499 36.415 T 21-04-2016 IPR014267 Glycosyltransferase Gtf1 GO:0016757 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.- HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 TIGRFAM TIGR02918 TIGR02918: accessory Sec system glycosylation protein GtfA 1 499 1.1E-258 T 21-04-2016 IPR014267 Glycosyltransferase Gtf1 GO:0016757 KEGG: 00051+2.4.1.-|KEGG: 00512+2.4.1.-|KEGG: 00513+2.4.1.-|KEGG: 00514+2.4.1.-|KEGG: 00522+2.4.1.-|KEGG: 00533+2.4.1.-|KEGG: 00540+2.4.1.-|KEGG: 00550+2.4.1.-|KEGG: 00561+2.4.1.-|KEGG: 00563+2.4.1.-|KEGG: 00600+2.4.1.-|KEGG: 00601+2.4.1.-|KEGG: 00603+2.4.1.-|KEGG: 00604+2.4.1.-|KEGG: 00906+2.4.1.-|KEGG: 00908+2.4.1.-|KEGG: 00941+2.4.1.-|KEGG: 00942+2.4.1.-|KEGG: 00944+2.4.1.-|KEGG: 00945+2.4.1.-|KEGG: 00965+2.4.1.- HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 SUPERFAMILY SSF53756 186 499 8.37E-34 T 21-04-2016 HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 Gene3D G3DSA:3.40.50.2000 316 463 1.2E-12 T 21-04-2016 HSISS4_RS01895 cf949c46844a2999234270a631b1825c 503 Pfam PF00534 Glycosyl transferases group 1 309 446 3.3E-22 T 21-04-2016 IPR001296 Glycosyl transferase, family 1 HSISS4_RS03135 390dc6c236f4815555018db2803264f9 258 Pfam PF12697 Alpha/beta hydrolase family 14 116 1.5E-9 T 21-04-2016 IPR000073 Alpha/beta hydrolase fold-1 HSISS4_RS03135 390dc6c236f4815555018db2803264f9 258 SUPERFAMILY SSF53474 3 255 4.9E-31 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03135 390dc6c236f4815555018db2803264f9 258 Gene3D G3DSA:3.40.50.1820 2 256 3.3E-29 T 21-04-2016 IPR029058 Alpha/Beta hydrolase fold HSISS4_RS03135 390dc6c236f4815555018db2803264f9 258 PANTHER PTHR10992 141 256 9.5E-24 T 21-04-2016 HSISS4_RS03135 390dc6c236f4815555018db2803264f9 258 PANTHER PTHR10992 3 119 9.5E-24 T 21-04-2016 HSISS4_RS04785 9025e2e712d2d5c78d5933be0c95c604 290 Pfam PF09375 Imelysin 48 283 4.6E-42 T 21-04-2016 HSISS4_RS04785 9025e2e712d2d5c78d5933be0c95c604 290 PANTHER PTHR39192 44 290 2.5E-93 T 21-04-2016 HSISS4_RS01300 68d990c7b4baa1f6a20fc7e0061c50bb 463 Pfam PF13777 Domain of unknown function (DUF4173) 312 457 1.5E-13 T 21-04-2016 IPR025231 Domain of unknown function DUF4173 HSISS4_RS00725 884d1c4e02a954898b57c4efe7554835 165 Pfam PF04542 Sigma-70 region 2 10 79 5.4E-5 T 21-04-2016 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS00725 884d1c4e02a954898b57c4efe7554835 165 SUPERFAMILY SSF88946 3 84 1.84E-7 T 21-04-2016 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 HSISS4_RS00725 884d1c4e02a954898b57c4efe7554835 165 Gene3D G3DSA:1.10.1740.10 3 85 5.2E-6 T 21-04-2016 HSISS4_RS01285 208d6a42ebf07182a4510d9ab79af45f 299 Gene3D G3DSA:1.10.260.40 7 94 7.6E-11 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS01285 208d6a42ebf07182a4510d9ab79af45f 299 SUPERFAMILY SSF47413 4 71 5.93E-9 T 21-04-2016 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 HSISS4_RS05025 9f682c751fc2ddab769d63e740f825c8 299 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 13 295 3.5E-37 T 21-04-2016 IPR005510 Protein of unknown function DUF314 HSISS4_RS03780 a3af56c8e797741117a8a795f5b5c2ae 321 PANTHER PTHR37804 5 318 1.7E-42 T 21-04-2016 HSISS4_RS03780 a3af56c8e797741117a8a795f5b5c2ae 321 Pfam PF07949 YbbR-like protein 240 316 2.0E-9 T 21-04-2016 IPR012505 YbbR-like HSISS4_RS03780 a3af56c8e797741117a8a795f5b5c2ae 321 Pfam PF07949 YbbR-like protein 153 231 1.6E-9 T 21-04-2016 IPR012505 YbbR-like HSISS4_RS03780 a3af56c8e797741117a8a795f5b5c2ae 321 Pfam PF07949 YbbR-like protein 55 138 3.1E-9 T 21-04-2016 IPR012505 YbbR-like HSISS4_RS02750 822a5f06b267ba092304a16e75ac3cfb 125 Pfam PF14520 Helix-hairpin-helix domain 66 118 5.5E-7 T 21-04-2016 HSISS4_RS02750 822a5f06b267ba092304a16e75ac3cfb 125 Gene3D G3DSA:1.10.150.20 68 118 2.4E-7 T 21-04-2016 HSISS4_RS02750 822a5f06b267ba092304a16e75ac3cfb 125 SUPERFAMILY SSF47794 68 119 3.14E-7 T 21-04-2016 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 HSISS4_RS06745 6f30253a976cdaacd794ff5ad7012bc0 148 TIGRFAM TIGR03711 acc_sec_asp3: accessory Sec system protein Asp3 8 140 3.2E-47 T 21-04-2016 IPR022259 Accessory Sec system protein Asp3 GO:0015031 HSISS4_RS06745 6f30253a976cdaacd794ff5ad7012bc0 148 Pfam PF15432 Accessory Sec secretory system ASP3 18 142 2.7E-42 T 21-04-2016 IPR022259 Accessory Sec system protein Asp3 GO:0015031 HSISS4_RS08880 2648c9ebbb6eee939bec4f7a67443312 148 PANTHER PTHR11241 19 148 2.1E-28 T 21-04-2016 HSISS4_RS08880 2648c9ebbb6eee939bec4f7a67443312 148 SUPERFAMILY SSF51283 10 147 6.94E-38 T 21-04-2016 IPR029054 dUTPase-like HSISS4_RS08880 2648c9ebbb6eee939bec4f7a67443312 148 Gene3D G3DSA:2.70.40.10 11 147 2.4E-40 T 21-04-2016 IPR029054 dUTPase-like HSISS4_RS08880 2648c9ebbb6eee939bec4f7a67443312 148 Pfam PF00692 dUTPase 19 146 6.2E-17 T 21-04-2016 IPR008180 Deoxyuridine triphosphate nucleotidohydrolase/Deoxycytidine triphosphate deaminase GO:0016787|GO:0046080 HSISS4_RS04795 3e887bf3b43ffe7f9c74526738d7de58 561 PANTHER PTHR31632:SF4 296 552 1.5E-53 T 21-04-2016 HSISS4_RS04795 3e887bf3b43ffe7f9c74526738d7de58 561 Pfam PF03239 Iron permease FTR1 family 300 420 2.0E-12 T 21-04-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 HSISS4_RS04795 3e887bf3b43ffe7f9c74526738d7de58 561 Pfam PF03239 Iron permease FTR1 family 424 520 8.9E-6 T 21-04-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 HSISS4_RS04795 3e887bf3b43ffe7f9c74526738d7de58 561 PANTHER PTHR31632 296 552 1.5E-53 T 21-04-2016 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 HSISS4_RS05840 4a7079a1e47b4cf3ddbfe4327d3c2ce9 322 Pfam PF06207 Protein of unknown function (DUF1002) 47 273 6.7E-61 T 21-04-2016 IPR009343 Protein of unknown function DUF1002 HSISS4_RS02980 625225b00b716128b84c44ae16e7ae9c 151 Pfam PF07997 Protein of unknown function (DUF1694) 1 119 3.8E-32 T 21-04-2016 IPR012543 Protein of unknown function DUF1694 HSISS4_RS02980 625225b00b716128b84c44ae16e7ae9c 151 SUPERFAMILY SSF160515 1 129 3.79E-33 T 21-04-2016 HSISS4_RS02980 625225b00b716128b84c44ae16e7ae9c 151 PIRSF PIRSF034303 1 150 7.9E-35 T 21-04-2016 IPR012543 Protein of unknown function DUF1694 HSISS4_RS02980 625225b00b716128b84c44ae16e7ae9c 151 Gene3D G3DSA:3.30.1330.30 1 130 6.4E-36 T 21-04-2016 IPR029064 50S ribosomal protein L30e-like HSISS4_RS04950 68cf95eddf521992b073d26d70ec2fba 251 Pfam PF08282 haloacid dehalogenase-like hydrolase 3 235 2.7E-28 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04950 68cf95eddf521992b073d26d70ec2fba 251 SUPERFAMILY SSF56784 3 233 1.53E-29 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04950 68cf95eddf521992b073d26d70ec2fba 251 PANTHER PTHR10000 3 250 1.5E-16 T 21-04-2016 HSISS4_RS04950 68cf95eddf521992b073d26d70ec2fba 251 Gene3D G3DSA:3.40.50.1000 170 235 5.3E-17 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04950 68cf95eddf521992b073d26d70ec2fba 251 Gene3D G3DSA:3.40.50.1000 3 81 5.3E-17 T 21-04-2016 IPR023214 HAD-like domain HSISS4_RS04315 6605ca7716daf267433b37234f8d569d 78 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 8 73 8.3E-21 T 21-04-2016 IPR009526 Protein of unknown function DUF1146 HSISS4_RS04315 6605ca7716daf267433b37234f8d569d 78 Pfam PF06612 Protein of unknown function (DUF1146) 14 64 2.9E-16 T 21-04-2016 IPR009526 Protein of unknown function DUF1146 HSISS4_RS04395 05a43c5c6f1fbbb4748a925f05344441 119 Pfam PF04304 Protein of unknown function (DUF454) 2 114 9.3E-39 T 21-04-2016 IPR007401 Protein of unknown function DUF454 HSISS4_RS04395 05a43c5c6f1fbbb4748a925f05344441 119 PANTHER PTHR35813 1 114 1.4E-44 T 21-04-2016 HSISS4_RS04395 05a43c5c6f1fbbb4748a925f05344441 119 PANTHER PTHR35813:SF1 1 114 1.4E-44 T 21-04-2016 HSISS4_RS04395 05a43c5c6f1fbbb4748a925f05344441 119 PIRSF PIRSF016789 1 119 1.8E-44 T 21-04-2016 IPR007401 Protein of unknown function DUF454 HSISS4_RS02685 f6b1e84df9211b918fdba6f745b6ba66 352 Pfam PF11311 Protein of unknown function (DUF3114) 3 256 4.5E-95 T 21-04-2016 IPR021462 Protein of unknown function DUF3114 HSISS4_RS06500 ca5e1afd31e9c5b656c0603ab17dffc6 108 Pfam PF08951 Enterocin A Immunity 10 81 3.5E-11 T 21-04-2016 IPR015046 Enterocin A Immunity HSISS4_RS01745 10696f465b1b21d2940a677972be90fc 219 Pfam PF08820 Domain of unknown function (DUF1803) 4 92 2.7E-27 T 21-04-2016 IPR014924 Protein of unknown function DUF1803 HSISS4_RS05045 25b83bf42e2e7777fcad2cce115100c2 243 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 45 237 9.4E-30 T 21-04-2016 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 HSISS4_RS05045 25b83bf42e2e7777fcad2cce115100c2 243 Pfam PF10040 Uncharacterized conserved protein (DUF2276) 122 235 2.1E-15 T 21-04-2016 IPR019267 CRISPR-associated protein Cas6, C-terminal HSISS4_RS09565 0641c1685fe6cc96a9a2a0b48a926898 290 Pfam PF13349 Putative adhesin 62 289 2.3E-25 T 21-04-2016 IPR025164 Putative adhesin HSISS4_RS03320 39ac6b425d9bf6d01ed71a86ec1364dd 146 PANTHER PTHR41243 1 145 9.9E-63 T 21-04-2016 HSISS4_RS03320 39ac6b425d9bf6d01ed71a86ec1364dd 146 Pfam PF10263 SprT-like family 18 141 2.7E-19 T 21-04-2016 IPR006640 SprT-like HSISS4_RS03320 39ac6b425d9bf6d01ed71a86ec1364dd 146 SMART SM00731 1 143 1.7E-48 T 21-04-2016 IPR006640 SprT-like HSISS4_RS03320 39ac6b425d9bf6d01ed71a86ec1364dd 146 Hamap MF_00745 Protein SprT-like. 1 143 38.955 T 21-04-2016 IPR023524 Uncharacterised protein family SprT-like HSISS4_RS03320 39ac6b425d9bf6d01ed71a86ec1364dd 146 PANTHER PTHR41243:SF1 1 145 9.9E-63 T 21-04-2016 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 Gene3D G3DSA:3.20.20.70 1 308 9.0E-79 T 21-04-2016 IPR013785 Aldolase-type TIM barrel GO:0003824 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 307 28.554 T 21-04-2016 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 305 2.5E-54 T 21-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 244 264 - T 21-04-2016 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 SUPERFAMILY SSF51395 1 308 4.28E-68 T 21-04-2016 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 PIRSF PIRSF000164 1 309 2.2E-66 T 21-04-2016 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 Reactome: REACT_1698 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 PANTHER PTHR11938:SF106 29 311 8.3E-170 T 21-04-2016 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 Pfam PF01180 Dihydroorotate dehydrogenase 5 292 4.7E-82 T 21-04-2016 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 HSISS4_RS04110 0c598bfff327b12368747437c6c3aaf4 311 PANTHER PTHR11938 29 311 8.3E-170 T 21-04-2016 HSISS4_RS03250 51d1eae9c0f589afcb71fa932eaad44b 249 Pfam PF02517 CAAX protease self-immunity 116 215 7.3E-10 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS08670 696ae38cb97ed2f9c1ecf7b891690da5 111 Pfam PF13728 F plasmid transfer operon protein 24 108 1.9E-7 T 21-04-2016 HSISS4_RS08670 696ae38cb97ed2f9c1ecf7b891690da5 111 SUPERFAMILY SSF52833 3 110 1.51E-23 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08670 696ae38cb97ed2f9c1ecf7b891690da5 111 Gene3D G3DSA:3.40.30.10 6 110 1.6E-31 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08115 849f04df9046b1fdd32685a2a32c9328 242 PANTHER PTHR41319 2 177 1.0E-42 T 21-04-2016 HSISS4_RS08115 849f04df9046b1fdd32685a2a32c9328 242 PANTHER PTHR41319:SF1 2 177 1.0E-42 T 21-04-2016 HSISS4_RS08115 849f04df9046b1fdd32685a2a32c9328 242 Pfam PF06265 Protein of unknown function (DUF1027) 30 112 3.3E-34 T 21-04-2016 IPR009370 Protein of unknown function DUF1027 HSISS4_RS08115 849f04df9046b1fdd32685a2a32c9328 242 PIRSF PIRSF012565 1 242 1.6E-70 T 21-04-2016 IPR009370 Protein of unknown function DUF1027 HSISS4_RS04300 eb7ee55c2f53801a21a54e82623e12ed 223 SUPERFAMILY SSF161098 23 138 7.33E-5 T 21-04-2016 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 HSISS4_RS04300 eb7ee55c2f53801a21a54e82623e12ed 223 Pfam PF16316 Domain of unknown function (DUF4956) 53 156 3.7E-10 T 21-04-2016 IPR032531 Protein of unknown function DUF4956 HSISS4_RS03655 6080a1c18fae6458739b4f973abd709c 85 Pfam PF02325 YGGT family 12 78 8.6E-15 T 21-04-2016 IPR003425 CCB3/YggT GO:0016020 HSISS4_RS07735 ed3e160131497bd88b2f2913fd417a9c 119 Pfam PF01883 Domain of unknown function DUF59 21 91 9.3E-11 T 21-04-2016 IPR002744 Domain of unknown function DUF59 HSISS4_RS07735 ed3e160131497bd88b2f2913fd417a9c 119 SUPERFAMILY SSF117916 19 112 7.85E-26 T 21-04-2016 HSISS4_RS00270 242f2c141b79cc2d1a79b628b0275812 299 Pfam PF01936 NYN domain 5 140 2.3E-11 T 21-04-2016 IPR021139 NYN domain, limkain-b1-type HSISS4_RS00270 242f2c141b79cc2d1a79b628b0275812 299 Gene3D G3DSA:3.40.50.1010 4 137 2.1E-12 T 21-04-2016 IPR029060 PIN domain-like HSISS4_RS03490 5d0d870e2c1319c5bf5b01bdadbdcf0a 384 Pfam PF01420 Type I restriction modification DNA specificity domain 18 157 1.6E-9 T 21-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HSISS4_RS03490 5d0d870e2c1319c5bf5b01bdadbdcf0a 384 Pfam PF01420 Type I restriction modification DNA specificity domain 198 372 7.0E-9 T 21-04-2016 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 HSISS4_RS03490 5d0d870e2c1319c5bf5b01bdadbdcf0a 384 SUPERFAMILY SSF116734 13 182 9.16E-29 T 21-04-2016 HSISS4_RS03490 5d0d870e2c1319c5bf5b01bdadbdcf0a 384 SUPERFAMILY SSF116734 186 383 4.91E-28 T 21-04-2016 HSISS4_RS08405 f928c2c55df34fe9881382fc0a9407aa 286 SUPERFAMILY SSF52833 99 210 2.88E-17 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08405 f928c2c55df34fe9881382fc0a9407aa 286 Gene3D G3DSA:3.40.30.10 95 210 4.3E-25 T 21-04-2016 IPR012336 Thioredoxin-like fold HSISS4_RS08375 a8d6a65704ad37e7b599ec26abfa06b7 129 PANTHER PTHR34297:SF1 4 129 7.4E-29 T 21-04-2016 HSISS4_RS08375 a8d6a65704ad37e7b599ec26abfa06b7 129 Pfam PF03780 Asp23 family, cell envelope-related function 7 108 8.3E-28 T 21-04-2016 IPR005531 Alkaline shock protein Asp23 HSISS4_RS08375 a8d6a65704ad37e7b599ec26abfa06b7 129 PANTHER PTHR34297 4 129 7.4E-29 T 21-04-2016 HSISS4_RS00305 1d05d025d2c1b01aa544edcdc60b1f66 151 Pfam PF11457 Protein of unknown function (DUF3021) 3 148 4.9E-32 T 21-04-2016 IPR021560 Protein of unknown function DUF3021 HSISS4_RS00445 140857f7c38d156aca782f21c54903ac 76 Pfam PF04226 Transglycosylase associated protein 33 70 5.7E-8 T 21-04-2016 IPR007341 Transglycosylase-associated protein GO:0016021 HSISS4_RS05415 91e255f9c542badfb321ed5630ade018 175 Pfam PF07155 ECF-type riboflavin transporter, S component 6 173 2.4E-10 T 21-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 HSISS4_RS04735 75d4e66fde086ee492d31a593ad60d70 655 Pfam PF09972 Predicted membrane protein (DUF2207) 36 582 2.1E-69 T 21-04-2016 IPR018702 Protein of unknown function DUF2207, membrane HSISS4_RS02100 29447829902bfd05af5b18143854afd0 235 PANTHER PTHR10509 13 231 1.0E-64 T 21-04-2016 HSISS4_RS02100 29447829902bfd05af5b18143854afd0 235 Pfam PF01596 O-methyltransferase 37 226 2.2E-28 T 21-04-2016 IPR002935 O-methyltransferase, family 3 GO:0008171 HSISS4_RS02100 29447829902bfd05af5b18143854afd0 235 SUPERFAMILY SSF53335 2 223 2.63E-45 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS02100 29447829902bfd05af5b18143854afd0 235 Gene3D G3DSA:3.40.50.150 8 226 1.1E-59 T 21-04-2016 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase HSISS4_RS02100 29447829902bfd05af5b18143854afd0 235 PANTHER PTHR10509:SF14 13 231 1.0E-64 T 21-04-2016 HSISS4_RS01535 818d4cb60527f180847c6b2cc7b8cc44 417 PANTHER PTHR33392 5 328 1.5E-105 T 21-04-2016 HSISS4_RS01535 818d4cb60527f180847c6b2cc7b8cc44 417 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 80 230 1.0E-41 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS01535 818d4cb60527f180847c6b2cc7b8cc44 417 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 81 230 4.2E-48 T 21-04-2016 IPR004474 Cell envelope-related transcriptional attenuator domain HSISS4_RS01535 818d4cb60527f180847c6b2cc7b8cc44 417 PANTHER PTHR33392:SF5 5 328 1.5E-105 T 21-04-2016 HSISS4_RS06755 0c95d81766353a8311ff9006cfc6712f 523 Pfam PF16993 Accessory Sec system protein Asp1 1 517 2.1E-176 T 21-04-2016 IPR022372 Accessory secretory system protein Asp1 GO:0015031 HSISS4_RS06755 0c95d81766353a8311ff9006cfc6712f 523 TIGRFAM TIGR03713 acc_sec_asp1: accessory Sec system protein Asp1 1 515 2.5E-150 T 21-04-2016 IPR022372 Accessory secretory system protein Asp1 GO:0015031 HSISS4_RS09000 54650b8bd6b5e1fee14dfe4831d44f0c 94 Pfam PF15513 Domain of unknown function (DUF4651) 32 92 7.5E-26 T 21-04-2016 IPR028105 Protein of unknown function DUF4651 HSISS4_RS02205 f8a8ba896bf07021c62a58a236627333 205 Pfam PF03413 Peptidase propeptide and YPEB domain 129 191 5.1E-4 T 21-04-2016 IPR025711 PepSY domain HSISS4_RS02205 f8a8ba896bf07021c62a58a236627333 205 Pfam PF03413 Peptidase propeptide and YPEB domain 34 95 2.9E-5 T 21-04-2016 IPR025711 PepSY domain HSISS4_RS09025 37f076ea5ba11f8c600b73e97d56cc51 218 PANTHER PTHR36435 1 218 9.2E-15 T 21-04-2016 HSISS4_RS09025 37f076ea5ba11f8c600b73e97d56cc51 218 Pfam PF02517 CAAX protease self-immunity 124 209 3.7E-12 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS09025 37f076ea5ba11f8c600b73e97d56cc51 218 PANTHER PTHR36435:SF1 1 218 9.2E-15 T 21-04-2016 HSISS4_RS00790 6eef5c6b16152c31d90754bba0350332 1195 Gene3D G3DSA:3.20.20.80 334 481 7.4E-5 T 21-04-2016 IPR013781 Glycoside hydrolase, catalytic domain GO:0005975 HSISS4_RS00790 6eef5c6b16152c31d90754bba0350332 1195 Pfam PF13199 Glycosyl hydrolase family 66 157 779 5.7E-121 T 21-04-2016 IPR025092 Glycosyl hydrolase family 66 HSISS4_RS00790 6eef5c6b16152c31d90754bba0350332 1195 SUPERFAMILY SSF51445 280 475 5.72E-9 T 21-04-2016 IPR017853 Glycoside hydrolase superfamily HSISS4_RS05885 ebc7cb6ef75547a251b3e5de051a5d1b 169 Pfam PF07155 ECF-type riboflavin transporter, S component 2 153 7.0E-18 T 21-04-2016 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 HSISS4_RS00515 6644eb5621eafb2504a51bb63399d4f9 256 Pfam PF07179 SseB protein N-terminal domain 150 242 5.1E-5 T 21-04-2016 IPR009839 SseB protein N-terminal domain HSISS4_RS00485 b5284594e8198e20e29e2bb03052d8ba 156 PANTHER PTHR36007:SF2 2 149 1.3E-61 T 21-04-2016 HSISS4_RS00485 b5284594e8198e20e29e2bb03052d8ba 156 PANTHER PTHR36007 2 149 1.3E-61 T 21-04-2016 HSISS4_RS00485 b5284594e8198e20e29e2bb03052d8ba 156 Pfam PF06695 Putative small multi-drug export protein 16 141 6.1E-43 T 21-04-2016 IPR009577 Putative small multi-drug export HSISS4_RS06245 2acf8045cb84e9029e5348f9564a3f02 86 Pfam PF03083 Sugar efflux transporter for intercellular exchange 8 80 6.1E-9 T 21-04-2016 IPR004316 SWEET sugar transporter GO:0016021 HSISS4_RS08430 80963dbf8047bfe29d983d2764de568f 223 Pfam PF06570 Protein of unknown function (DUF1129) 5 218 2.4E-77 T 21-04-2016 IPR009214 Protein of unknown function DUF1129 HSISS4_RS08430 80963dbf8047bfe29d983d2764de568f 223 PIRSF PIRSF033111 1 223 3.3E-77 T 21-04-2016 IPR009214 Protein of unknown function DUF1129 HSISS4_RS09425 0b938f8f708c3d087eaa1f7069b8a176 548 PIRSF PIRSF031639 10 548 2.4E-224 T 21-04-2016 IPR016978 Putative competence-induced protein Ccs4 HSISS4_RS04295 11b7370fcf54b3ebea5760cd538cb1af 242 Pfam PF09359 VTC domain 9 225 3.1E-15 T 21-04-2016 IPR018966 VTC domain HSISS4_RS03975 2bb17322b55ee4f5d2994cd91e19acac 87 Pfam PF03083 Sugar efflux transporter for intercellular exchange 9 81 2.6E-7 T 21-04-2016 IPR004316 SWEET sugar transporter GO:0016021 HSISS4_RS00655 aaff0eda465c3f15ded99b6c4c300c89 265 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 106 240 5.8E-38 T 21-04-2016 IPR003709 Peptidase M15B GO:0006508|GO:0008233 HSISS4_RS00655 aaff0eda465c3f15ded99b6c4c300c89 265 PANTHER PTHR34385 16 265 5.1E-40 T 21-04-2016 HSISS4_RS00655 aaff0eda465c3f15ded99b6c4c300c89 265 PANTHER PTHR34385:SF1 16 265 5.1E-40 T 21-04-2016 HSISS4_RS00655 aaff0eda465c3f15ded99b6c4c300c89 265 SUPERFAMILY SSF55166 100 248 9.16E-27 T 21-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HSISS4_RS00655 aaff0eda465c3f15ded99b6c4c300c89 265 Gene3D G3DSA:3.30.1380.10 112 196 1.3E-7 T 21-04-2016 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain HSISS4_RS08240 abf7ba60426878b8f8989596d259eb6c 271 Pfam PF01061 ABC-2 type transporter 33 202 4.6E-10 T 21-04-2016 IPR013525 ABC-2 type transporter GO:0016020 HSISS4_RS07230 4a3d423f9bfc12eac21158396fad5cc8 324 SUPERFAMILY SSF55136 246 322 9.94E-11 T 21-04-2016 IPR011256 Regulatory factor, effector binding domain HSISS4_RS07230 4a3d423f9bfc12eac21158396fad5cc8 324 Gene3D G3DSA:3.20.80.10 253 321 3.4E-7 T 21-04-2016 IPR011256 Regulatory factor, effector binding domain HSISS4_RS07065 c27bb1aa334ea41a37201fb8132ffaca 594 Pfam PF05045 Rhamnan synthesis protein F 34 518 5.1E-185 T 21-04-2016 IPR007739 Rhamnan synthesis F HSISS4_RS08085 195c571c2e58a1f47b863b2b55be3b02 76 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 6 65 2.7E-12 T 21-04-2016 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 HSISS4_RS00820 d6678d186dd650c986faad770265d3d1 196 Pfam PF04892 VanZ like family 81 181 5.2E-12 T 21-04-2016 IPR006976 VanZ-like HSISS4_RS01100 f9a7eb3c49565c52e2379e9e5a7776fe 147 Pfam PF05656 Protein of unknown function (DUF805) 13 135 1.8E-16 T 21-04-2016 IPR008523 Protein of unknown function DUF805 GO:0016021 HSISS4_RS03180 0b94b1d4815e2b900d0d72ecc148de2b 248 Pfam PF02517 CAAX protease self-immunity 114 212 2.0E-12 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS09055 799c694b35479f47952e11a4751c368a 76 Pfam PF11773 Type II secretory pathway pseudopilin 1 74 5.9E-28 T 21-04-2016 IPR021749 Type II secretory pathway pseudopilin HSISS4_RS03265 b8821c8186fb3bb90187b07ce3dafece 130 Pfam PF08349 Protein of unknown function (DUF1722) 18 126 4.5E-27 T 21-04-2016 IPR013560 Domain of unknown function DUF1722 HSISS4_RS00245 e3059a17fcacc4c88361992888498f03 595 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 173 316 1.6E-8 T 21-04-2016 IPR000477 Reverse transcriptase domain HSISS4_RS08105 e9f4bc09ca7ee1cb43c35215f2c384d8 175 PANTHER PTHR36834 24 169 8.2E-22 T 21-04-2016 HSISS4_RS08105 e9f4bc09ca7ee1cb43c35215f2c384d8 175 Pfam PF04892 VanZ like family 28 165 2.3E-18 T 21-04-2016 IPR006976 VanZ-like HSISS4_RS02640 c44e38825bce892831e2eb4bc1004439 182 PANTHER PTHR11839 6 181 3.7E-55 T 21-04-2016 HSISS4_RS02640 c44e38825bce892831e2eb4bc1004439 182 Pfam PF00293 NUDIX domain 43 154 2.4E-11 T 21-04-2016 IPR000086 NUDIX hydrolase domain GO:0016787 HSISS4_RS02640 c44e38825bce892831e2eb4bc1004439 182 PANTHER PTHR11839:SF9 6 181 3.7E-55 T 21-04-2016 HSISS4_RS02640 c44e38825bce892831e2eb4bc1004439 182 Gene3D G3DSA:3.90.79.10 4 178 4.7E-50 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS02640 c44e38825bce892831e2eb4bc1004439 182 SUPERFAMILY SSF55811 6 178 1.76E-42 T 21-04-2016 IPR015797 NUDIX hydrolase domain-like GO:0016787 HSISS4_RS01350 9be53886f0c9b0343885f7994116c6f4 259 Pfam PF02361 Cobalt transport protein 28 227 3.5E-10 T 21-04-2016 IPR003339 ABC/ECF transporter, transmembrane component HSISS4_RS08565 e781ddf5f5dc6c2e173dd497c1535d2e 167 Pfam PF06081 Aromatic acid exporter family member 1 11 156 1.5E-14 T 21-04-2016 IPR010343 Aromatic acid exporter family member 1 HSISS4_RS06130 6026313108c0224ea38c3b1f87d68d40 164 Pfam PF03692 Putative zinc- or iron-chelating domain 52 140 7.4E-15 T 21-04-2016 IPR005358 Putative zinc- or iron-chelating domain containing protein HSISS4_RS06725 99be6434455b340b9a0fa94f44a537d3 59 Pfam PF16996 Accessory secretory protein Sec Asp4 3 57 2.7E-28 T 21-04-2016 IPR031551 Accessory secretory protein Asp4 HSISS4_RS02625 a1c45b5aa4d8a414ac103f4b6590fa13 239 Pfam PF12698 ABC-2 family transporter protein 51 227 1.3E-11 T 21-04-2016 HSISS4_RS05015 250bdfb3c54fc383999f0b4688c01095 386 TIGRFAM TIGR02672 cas_csm6: CRISPR type III-A/MTUBE-associated protein Csm6 53 288 8.1E-89 T 21-04-2016 IPR013489 CRISPR-associated protein Csm6 HSISS4_RS05015 250bdfb3c54fc383999f0b4688c01095 386 Pfam PF09659 CRISPR-associated protein (Cas_Csm6) 74 296 6.3E-36 T 21-04-2016 IPR013489 CRISPR-associated protein Csm6 HSISS4_RS08520 bad05475a8765df459e0b304338a842b 230 Pfam PF03591 AzlC protein 13 153 2.6E-35 T 21-04-2016 IPR011606 Branched-chain amino acid transport, permease HSISS4_RS08520 bad05475a8765df459e0b304338a842b 230 PANTHER PTHR34979 4 225 1.9E-49 T 21-04-2016 HSISS4_RS08075 2b324a29ce851069d6d7c866cde9a85c 98 Pfam PF08951 Enterocin A Immunity 14 86 2.6E-9 T 21-04-2016 IPR015046 Enterocin A Immunity HSISS4_RS00845 3dc8657185c5f9ee1ef63932e7e1839c 123 Pfam PF11457 Protein of unknown function (DUF3021) 13 121 1.2E-12 T 21-04-2016 IPR021560 Protein of unknown function DUF3021 HSISS4_RS06030 51672062b1a3580bfcbb09dfefa140f3 239 Pfam PF12698 ABC-2 family transporter protein 52 227 1.6E-8 T 21-04-2016 HSISS4_RS02780 48dff3a7196a86e4b5905cef7513654d 76 Pfam PF11184 Protein of unknown function (DUF2969) 1 75 1.7E-23 T 21-04-2016 IPR021351 Protein of unknown function DUF2969 HSISS4_RS06205 cecea74fa108ef8072499493e61dedc5 150 Pfam PF11694 Protein of unknown function (DUF3290) 2 144 6.7E-44 T 21-04-2016 IPR021707 Protein of unknown function DUF3290 HSISS4_RS06420 dcdb83d8033f14005c08f7e8cc906319 458 Pfam PF02687 FtsX-like permease family 304 450 2.4E-22 T 21-04-2016 IPR003838 ABC transporter permease protein domain GO:0016020 HSISS4_RS06715 6d1cf8cbef7684f8a07accdd28473324 237 Gene3D G3DSA:3.10.20.320 112 229 1.1E-8 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06715 6d1cf8cbef7684f8a07accdd28473324 237 Pfam PF06458 MucBP domain 213 233 0.049 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06715 6d1cf8cbef7684f8a07accdd28473324 237 Pfam PF06458 MucBP domain 115 202 1.4E-6 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS06715 6d1cf8cbef7684f8a07accdd28473324 237 Pfam PF06458 MucBP domain 19 109 7.2E-4 T 21-04-2016 IPR009459 MucBP domain HSISS4_RS05100 77f7ae098d74550b42c4759cc0003905 232 Pfam PF12698 ABC-2 family transporter protein 53 219 2.1E-8 T 21-04-2016 HSISS4_RS03935 e71703b76ac5d6ee143e448abf97032f 227 Pfam PF16316 Domain of unknown function (DUF4956) 33 148 6.3E-13 T 21-04-2016 IPR032531 Protein of unknown function DUF4956 HSISS4_RS06320 6024074991f875c71c8f712090bd4abd 103 Pfam PF11611 Domain of unknown function (DUF4352) 2 96 6.0E-22 T 21-04-2016 IPR029051 Domain of unknown function DUF4352 HSISS4_RS06320 6024074991f875c71c8f712090bd4abd 103 Gene3D G3DSA:2.60.40.1240 2 102 2.7E-20 T 21-04-2016 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain HSISS4_RS03350 34305885be239f0fe856848dd907b4f9 98 Pfam PF11674 Protein of unknown function (DUF3270) 6 89 1.1E-31 T 21-04-2016 IPR021688 Protein of unknown function DUF3270 HSISS4_RS01445 e4cc58c05d95967e2d414eec12816af4 391 Pfam PF07261 Replication initiation and membrane attachment 268 329 1.7E-6 T 21-04-2016 IPR006343 Replication protein, DnaD/DnaB domain HSISS4_RS04660 0f20a1806e8a6154bc0b63be2ce8705e 325 Pfam PF09992 Phosphodiester glycosidase 156 251 1.0E-6 T 21-04-2016 IPR018711 Phosphodiester glycosidase HSISS4_RS01200 1ef7f258ffe9ac74e23d2ae28b23b907 378 Pfam PF17118 Domain of unknown function (DUF5105) 162 352 1.3E-11 T 21-04-2016 IPR031343 Domain of unknown function DUF5105 HSISS4_RS07995 8ceab01c58021809de830fbf2bd41383 74 Pfam PF13268 Protein of unknown function (DUF4059) 1 72 3.8E-31 T 21-04-2016 IPR025134 Protein of unknown function DUF4059 HSISS4_RS04285 2d55b8c466fbf36fb02f42c35c70d804 483 Pfam PF16933 Putative exopolysaccharide Exporter (EPS-E) 1 451 1.3E-120 T 21-04-2016 IPR031617 Putative exopolysaccharide exporter HSISS4_RS08950 f3a5c0fdc833e9bbd95d19f85f5a25a7 52 TIGRFAM TIGR03949 bact_IIb_cerein: class IIb bacteriocin, lactobin A/cerein 7B family 3 47 4.2E-13 T 21-04-2016 IPR023991 Bacteriocin, class IIb, lactobin A/cerein 7B family HSISS4_RS06270 2d408ebcb3c7d7cceb504cd70e2bf82b 265 SUPERFAMILY SSF81321 8 180 1.1E-5 T 21-04-2016 HSISS4_RS06270 2d408ebcb3c7d7cceb504cd70e2bf82b 265 Pfam PF11368 Protein of unknown function (DUF3169) 12 257 2.4E-49 T 21-04-2016 IPR021509 Protein of unknown function DUF3169 HSISS4_RS07460 e4dbd7bd59ec66f827e488cc0487d1ec 328 Pfam PF13280 WYL domain 149 318 5.0E-14 T 21-04-2016 IPR026881 WYL domain HSISS4_RS02355 e2e55c3ba310ac3e45e6f6f7c8b3bde4 358 Pfam PF08460 Bacterial SH3 domain 295 357 1.4E-18 T 21-04-2016 IPR003646 SH3-like domain, bacterial-type HSISS4_RS01070 876b0058897ca6ac4107e2fa46854dcf 143 Pfam PF11457 Protein of unknown function (DUF3021) 1 130 4.2E-17 T 21-04-2016 IPR021560 Protein of unknown function DUF3021 HSISS4_RS03285 fb0ba8f49d0b8cf34c77bd01f9c98c09 203 Pfam PF02517 CAAX protease self-immunity 95 193 3.2E-12 T 21-04-2016 IPR003675 CAAX amino terminal protease GO:0016020 HSISS4_RS02430 96b66d620600a47261681b221f03d138 412 Pfam PF04103 CD20-like family 123 214 4.8E-6 T 21-04-2016 IPR007237 CD20-like family GO:0016021