locus-tag	class	description
FHI56_RS00080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHI56_RS00145	COG4974	Belongs to the 'phage' integrase family
FHI56_RS00260	COG1131	(ABC) transporter
FHI56_RS00335	COG1401	restriction endodeoxyribonuclease activity
FHI56_RS00435	COG0542	response to heat
FHI56_RS00525	COG1725	Transcriptional regulator
FHI56_RS00530	COG0494	nUDIX hydrolase
FHI56_RS00550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FHI56_RS00560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FHI56_RS00600	COG2826	transposase and inactivated derivatives, IS30 family
FHI56_RS00610	COG4555	ABC transporter
FHI56_RS00700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHI56_RS00720	COG4974	Belongs to the 'phage' integrase family
FHI56_RS00785	COG0542	response to heat
FHI56_RS00790	COG1396	sequence-specific DNA binding
FHI56_RS00830	COG2197	response regulator
FHI56_RS00845	COG1136	(ABC) transporter
FHI56_RS00960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHI56_RS00975	COG0494	nUDIX hydrolase
FHI56_RS00985	COG0504	CTP synthase activity
FHI56_RS01000	COG0668	transmembrane transport
FHI56_RS01110	COG0351	phosphomethylpyrimidine kinase
FHI56_RS01130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FHI56_RS01145	COG1876	peptidase activity
FHI56_RS01150	COG0588	phosphoglycerate mutase activity
FHI56_RS01160	COG3830	Belongs to the UPF0237 family
FHI56_RS01170	COG4509	Sortase family
FHI56_RS01210	COG1674	ftsk spoiiie
FHI56_RS01245	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FHI56_RS01250	COG1476	TRANSCRIPTIONal
FHI56_RS01265	COG3688	RNA-binding protein containing a PIN domain
FHI56_RS01270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHI56_RS01280	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FHI56_RS01290	COG1045	serine acetyltransferase
FHI56_RS01305	COG1686	Belongs to the peptidase S11 family
FHI56_RS01310	COG1686	Belongs to the peptidase S11 family
FHI56_RS01320	COG0542	response to heat
FHI56_RS01325	COG4463	regulation of RNA biosynthetic process
FHI56_RS01345	COG0450	alkyl hydroperoxide reductase
FHI56_RS01350	COG3634	alkyl hydroperoxide reductase activity
FHI56_RS01385	COG1846	Transcriptional regulator
FHI56_RS01395	COG2309	aminopeptidase activity
FHI56_RS01435	COG0582	viral genome integration into host DNA
FHI56_RS01520	COG1393	Belongs to the ArsC family
FHI56_RS01530	COG1546	Belongs to the CinA family
FHI56_RS01530	COG1058	Belongs to the CinA family
FHI56_RS01535	COG0519	Catalyzes the synthesis of GMP from XMP
FHI56_RS01575	COG4550	Control of competence regulator ComK, YlbF/YmcA
FHI56_RS01600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FHI56_RS01630	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FHI56_RS01640	COG0151	Belongs to the GarS family
FHI56_RS01660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FHI56_RS01665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FHI56_RS01675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FHI56_RS01685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FHI56_RS01700	COG0436	Aminotransferase
FHI56_RS01830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FHI56_RS01860	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FHI56_RS01865	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FHI56_RS01875	COG0012	GTP binding
FHI56_RS01885	COG0592	DNA-directed DNA polymerase activity
FHI56_RS01895	COG1475	DNA binding
FHI56_RS01900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FHI56_RS01935	COG0488	(ABC) transporter
FHI56_RS01940	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHI56_RS01965	COG0612	Peptidase, M16
FHI56_RS01970	COG0612	Peptidase, M16
FHI56_RS01980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FHI56_RS01995	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHI56_RS02000	COG3584	3D domain protein
FHI56_RS02000	COG1388	LysM domain
FHI56_RS02005	COG0741	lytic transglycosylase activity
FHI56_RS02020	COG2095	MarC family integral membrane protein
FHI56_RS02025	COG0494	nUDIX hydrolase
FHI56_RS02045	COG0305	Participates in initiation and elongation during chromosome replication
FHI56_RS02065	COG3759	membrane
FHI56_RS02075	COG1511	domain protein
FHI56_RS02075	COG1511	domain protein
FHI56_RS02090	COG1695	Transcriptional regulator
FHI56_RS02095	COG0494	nUDIX hydrolase
FHI56_RS02115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FHI56_RS02125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FHI56_RS02135	COG1263	PTS System
FHI56_RS02135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHI56_RS02135	COG2190	(PTS) system
FHI56_RS02165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FHI56_RS02175	COG0602	queuosine metabolic process
FHI56_RS02215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FHI56_RS02220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FHI56_RS02245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FHI56_RS02270	COG0051	transcription antitermination factor activity, RNA binding
FHI56_RS02340	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FHI56_RS02375	COG0201	protein transport
FHI56_RS02445	COG4475	Protein of unknown function (DUF436)
FHI56_RS02450	COG2188	Transcriptional regulator
FHI56_RS02460	COG0366	Alpha amylase catalytic
FHI56_RS02465	COG3590	peptidase
FHI56_RS02470	COG1454	alcohol dehydrogenase
FHI56_RS02470	COG1012	belongs to the aldehyde dehydrogenase family
FHI56_RS02490	COG0534	Mate efflux family protein
FHI56_RS02500	COG1461	Dihydroxyacetone kinase
FHI56_RS02505	COG0129	dihydroxy-acid dehydratase activity
FHI56_RS02510	COG0028	Belongs to the TPP enzyme family
FHI56_RS02515	COG0440	acetolactate synthase activity
FHI56_RS02520	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FHI56_RS02550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FHI56_RS02555	COG1459	type II secretion system
FHI56_RS02610	COG1266	CAAX protease self-immunity
FHI56_RS02615	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FHI56_RS02620	COG1363	Peptidase, m42
FHI56_RS02630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FHI56_RS02640	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHI56_RS02680	COG2226	methyltransferase
FHI56_RS02700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FHI56_RS02705	COG0705	Rhomboid family
FHI56_RS02705	COG0457	Tetratricopeptide repeat
FHI56_RS02710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FHI56_RS02730	COG1053	succinate dehydrogenase
FHI56_RS02730	COG3976	FMN-binding domain protein
FHI56_RS02730	COG0431	NADPH-dependent FMN reductase
FHI56_RS02740	COG0756	dUTP diphosphatase activity
FHI56_RS02780	COG4166	transmembrane transport
FHI56_RS02835	COG0706	membrane insertase activity
FHI56_RS02850	COG2249	NAD(P)H dehydrogenase (quinone) activity
FHI56_RS02910	COG3118	belongs to the thioredoxin family
FHI56_RS02915	COG1832	CoA-binding protein
FHI56_RS02960	COG3481	metal-dependent phosphohydrolase, HD sub domain
FHI56_RS02965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FHI56_RS02995	COG0126	phosphoglycerate kinase activity
FHI56_RS03005	COG0789	Transcriptional regulator
FHI56_RS03010	COG0174	glutamine synthetase
FHI56_RS03015	COG3942	CHAP domain
FHI56_RS03030	COG1214	PFAM Peptidase M22, glycoprotease
FHI56_RS03035	COG0456	acetyltransferase
FHI56_RS03045	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FHI56_RS03055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FHI56_RS03060	COG0681	Belongs to the peptidase S26 family
FHI56_RS03085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHI56_RS03085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FHI56_RS03115	COG1674	ftsk spoiiie
FHI56_RS03125	COG2946	Replication initiation factor
FHI56_RS03155	COG0741	lytic transglycosylase activity
FHI56_RS03155	COG0791	NLP P60 protein
FHI56_RS03170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FHI56_RS03315	COG2003	Belongs to the UPF0758 family
FHI56_RS03350	COG3843	relaxase mobilization nuclease domain protein
FHI56_RS03360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FHI56_RS03455	COG0006	proline dipeptidase activity
FHI56_RS03460	COG2131	deaminase
FHI56_RS03465	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FHI56_RS03480	COG1609	Transcriptional regulator
FHI56_RS03485	COG1621	beta-fructofuranosidase activity
FHI56_RS03490	COG2190	(PTS) system
FHI56_RS03490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHI56_RS03490	COG1263	PTS System
FHI56_RS03495	COG1940	carbohydrate kinase activity
FHI56_RS03500	COG1482	cell wall glycoprotein biosynthetic process
FHI56_RS03510	COG0653	protein targeting
FHI56_RS03515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FHI56_RS03520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FHI56_RS03535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FHI56_RS03555	COG3655	Transcriptional regulator
FHI56_RS03560	COG0252	asparaginase activity
FHI56_RS03565	COG0561	phosphatase activity
FHI56_RS03590	COG0443	Heat shock 70 kDa protein
FHI56_RS03600	COG1116	anion transmembrane transporter activity
FHI56_RS03640	COG1811	Na channel or pump
FHI56_RS03645	COG4152	abc transporter atp-binding protein
FHI56_RS03655	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FHI56_RS03660	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FHI56_RS03665	COG3152	Membrane
FHI56_RS03670	COG3152	Membrane
FHI56_RS03700	COG0768	penicillin binding
FHI56_RS03710	COG0513	Belongs to the DEAD box helicase family
FHI56_RS03725	COG4470	Protein conserved in bacteria
FHI56_RS03745	COG1132	(ABC) transporter
FHI56_RS03750	COG1132	(ABC) transporter
FHI56_RS03765	COG3290	protein histidine kinase activity
FHI56_RS03810	COG2826	transposase and inactivated derivatives, IS30 family
FHI56_RS03825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FHI56_RS03845	COG1882	Formate acetyltransferase
FHI56_RS03860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS03865	COG0765	amino acid transport
FHI56_RS03870	COG1126	abc transporter atp-binding protein
FHI56_RS03885	COG0742	ribosomal rna small subunit methyltransferase
FHI56_RS03890	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FHI56_RS03895	COG3480	Lon protease (S16) C-terminal proteolytic domain
FHI56_RS03900	COG1242	4 iron, 4 sulfur cluster binding
FHI56_RS03905	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
FHI56_RS03920	COG1119	ATPase activity
FHI56_RS03925	COG1253	flavin adenine dinucleotide binding
FHI56_RS03935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FHI56_RS03945	COG0589	response to stress
FHI56_RS03950	COG0436	Aminotransferase
FHI56_RS03960	COG1335	isochorismatase
FHI56_RS03965	COG2723	6-phospho-beta-galactosidase activity
FHI56_RS04000	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
FHI56_RS04005	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHI56_RS04010	COG1534	Rna-binding protein
FHI56_RS04015	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FHI56_RS04020	COG1713	HD superfamily hydrolase involved in NAD metabolism
FHI56_RS04025	COG0799	negative regulation of ribosome biogenesis
FHI56_RS04030	COG2226	methyltransferase
FHI56_RS04070	COG0537	adenosine 5'-monophosphoramidase activity
FHI56_RS04075	COG1131	(ABC) transporter
FHI56_RS04100	COG2081	HI0933 family
FHI56_RS04110	COG2151	metal-sulfur cluster biosynthetic enzyme
FHI56_RS04120	COG2176	DNA-directed DNA polymerase activity
FHI56_RS04125	COG0789	Transcriptional regulator
FHI56_RS04135	COG1136	(ABC) transporter
FHI56_RS04135	COG4591	ABC-type transport system involved in lipoprotein release permease component
FHI56_RS04155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHI56_RS04175	COG0577	efflux transmembrane transporter activity
FHI56_RS04175	COG1136	(ABC) transporter
FHI56_RS04180	COG0287	Prephenate dehydrogenase
FHI56_RS04180	COG1605	Chorismate mutase
FHI56_RS04185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FHI56_RS04190	COG0512	Glutamine amidotransferase of anthranilate synthase
FHI56_RS04205	COG0135	phosphoribosylanthranilate isomerase activity
FHI56_RS04210	COG0133	tryptophan synthase activity
FHI56_RS04215	COG0159	tryptophan synthase activity
FHI56_RS04235	COG2217	Heavy metal translocating P-type atpase
FHI56_RS04245	COG1181	Belongs to the D-alanine--D-alanine ligase family
FHI56_RS04250	COG0765	amino acid transport
FHI56_RS04255	COG0765	amino acid transport
FHI56_RS04260	COG1126	abc transporter atp-binding protein
FHI56_RS04265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS04285	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHI56_RS04315	COG0513	Belongs to the DEAD box helicase family
FHI56_RS04325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FHI56_RS04335	COG0204	Acyl-transferase
FHI56_RS04340	COG1596	polysaccharide export
FHI56_RS04340	COG1555	photosystem II stabilization
FHI56_RS04345	COG2333	competence protein COMEC
FHI56_RS04345	COG0658	competence protein
FHI56_RS04350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FHI56_RS04355	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHI56_RS04360	COG4109	DRTGG domain
FHI56_RS04365	COG0024	Methionine aminopeptidase
FHI56_RS04375	COG4708	membrane
FHI56_RS04385	COG1597	lipid kinase activity
FHI56_RS04410	COG0708	Exodeoxyribonuclease III
FHI56_RS04430	COG3615	Tellurite resistance protein tehB
FHI56_RS04430	COG0500	methyltransferase
FHI56_RS04465	COG0285	dihydrofolate synthase activity
FHI56_RS04470	COG0531	amino acid
FHI56_RS04510	COG1176	ABC-type spermidine putrescine transport system, permease component I
FHI56_RS04515	COG1177	transmembrane transport
FHI56_RS04530	COG0346	lactoylglutathione lyase activity
FHI56_RS04535	COG1940	carbohydrate kinase activity
FHI56_RS04550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FHI56_RS04555	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FHI56_RS04560	COG1393	Belongs to the ArsC family
FHI56_RS04580	COG0356	it plays a direct role in the translocation of protons across the membrane
FHI56_RS04615	COG0772	Belongs to the SEDS family
FHI56_RS04630	COG0149	triose-phosphate isomerase activity
FHI56_RS04655	COG0470	DNA polymerase III
FHI56_RS04660	COG1774	PSP1 C-terminal conserved region
FHI56_RS04665	COG4467	Involved in initiation control of chromosome replication
FHI56_RS04675	COG0004	ammonium transporteR
FHI56_RS04680	COG0347	Belongs to the P(II) protein family
FHI56_RS04685	COG1388	LysM domain
FHI56_RS04685	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHI56_RS04705	COG1283	sodium-dependent phosphate transmembrane transporter activity
FHI56_RS04735	COG1113	amino acid transport
FHI56_RS04745	COG2190	(PTS) system
FHI56_RS04745	COG1263	PTS System
FHI56_RS04745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHI56_RS04785	COG0564	pseudouridine synthase activity
FHI56_RS04805	COG0505	Belongs to the CarA family
FHI56_RS04825	COG1136	(ABC) transporter
FHI56_RS04830	COG0577	efflux transmembrane transporter activity
FHI56_RS04880	COG1132	(ABC) transporter
FHI56_RS04920	COG1187	pseudouridine synthase activity
FHI56_RS04925	COG1473	amidohydrolase
FHI56_RS04930	COG0686	Belongs to the AlaDH PNT family
FHI56_RS04940	COG2267	carboxylic ester hydrolase activity
FHI56_RS04945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHI56_RS04975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHI56_RS05010	COG0438	transferase activity, transferring glycosyl groups
FHI56_RS05020	COG0596	Alpha beta hydrolase
FHI56_RS05035	COG1272	protein, Hemolysin III
FHI56_RS05050	COG3425	synthase
FHI56_RS05060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FHI56_RS05080	COG0833	amino acid
FHI56_RS05085	COG2040	homocysteine
FHI56_RS05105	COG0187	DNA topoisomerase II activity
FHI56_RS05125	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FHI56_RS05145	COG0539	negative regulation of cytoplasmic translation
FHI56_RS05180	COG0494	nUDIX hydrolase
FHI56_RS05185	COG0542	response to heat
FHI56_RS05190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FHI56_RS05195	COG4703	Protein of unknown function (DUF1797)
FHI56_RS05200	COG0765	amino acid transport
FHI56_RS05205	COG1126	abc transporter atp-binding protein
FHI56_RS05235	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FHI56_RS05240	COG0768	penicillin binding
FHI56_RS05245	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FHI56_RS05260	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FHI56_RS05265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FHI56_RS05270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FHI56_RS05275	COG0237	dephospho-CoA kinase activity
FHI56_RS05280	COG2814	Major facilitator Superfamily
FHI56_RS05295	COG0557	exoribonuclease II activity
FHI56_RS05310	COG1185	polyribonucleotide nucleotidyltransferase activity
FHI56_RS05315	COG0006	proline dipeptidase activity
FHI56_RS05320	COG1609	Transcriptional regulator
FHI56_RS05350	COG1368	sulfuric ester hydrolase activity
FHI56_RS05355	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FHI56_RS05380	COG0287	Prephenate dehydrogenase
FHI56_RS05395	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FHI56_RS05405	COG0077	Prephenate dehydratase
FHI56_RS05445	COG0488	(ABC) transporter
FHI56_RS05490	COG0640	Transcriptional regulator
FHI56_RS05495	COG2217	Heavy metal translocating P-type atpase
FHI56_RS05515	COG2807	transmembrane transport
FHI56_RS05520	COG1307	EDD domain protein, DegV family
FHI56_RS05530	COG1418	mRNA catabolic process
FHI56_RS05545	COG1442	glycosyl transferase family 8
FHI56_RS05545	COG1216	Glycosyl transferase, family 2
FHI56_RS05560	COG0477	Major facilitator Superfamily
FHI56_RS05585	COG1120	ATPase activity
FHI56_RS05595	COG2819	hydrolase of the alpha beta superfamily
FHI56_RS05600	COG2226	methyltransferase
FHI56_RS05665	COG0659	secondary active sulfate transmembrane transporter activity
FHI56_RS05675	COG1518	maintenance of DNA repeat elements
FHI56_RS05680	COG3512	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FHI56_RS05690	COG3689	TIGRFAM TIGR03943 family protein
FHI56_RS05695	COG0701	Predicted permease
FHI56_RS05700	COG2183	response to ionizing radiation
FHI56_RS05745	COG0826	peptidase U32
FHI56_RS05755	COG1268	BioY protein
FHI56_RS05765	COG4443	Transcriptional Coactivator p15 (PC4)
FHI56_RS05770	COG1914	H( )-stimulated, divalent metal cation uptake system
FHI56_RS05790	COG1388	LysM domain
FHI56_RS05790	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHI56_RS05805	COG0588	phosphoglycerate mutase activity
FHI56_RS05810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FHI56_RS05825	COG0561	phosphatase activity
FHI56_RS05840	COG4221	oxidoreductase activity
FHI56_RS05845	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FHI56_RS05850	COG3620	sequence-specific DNA binding
FHI56_RS05855	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FHI56_RS05905	COG1704	LemA family
FHI56_RS05910	COG0501	Belongs to the peptidase M48B family
FHI56_RS05945	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FHI56_RS05955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FHI56_RS05965	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FHI56_RS05970	COG0783	Belongs to the Dps family
FHI56_RS05975	COG0735	belongs to the Fur family
FHI56_RS05985	COG1940	carbohydrate kinase activity
FHI56_RS05990	COG1217	gtp-binding protein TYPA
FHI56_RS06015	COG0849	cell division
FHI56_RS06025	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FHI56_RS06035	COG0762	integral membrane protein
FHI56_RS06045	COG3599	regulation of cell shape
FHI56_RS06055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHI56_RS06060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FHI56_RS06065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FHI56_RS06070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FHI56_RS06075	COG0372	Belongs to the citrate synthase family
FHI56_RS06115	COG0513	Belongs to the DEAD box helicase family
FHI56_RS06125	COG0488	(ABC) transporter
FHI56_RS06140	COG0392	lysyltransferase activity
FHI56_RS06140	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHI56_RS06145	COG3442	glutamine amidotransferase
FHI56_RS06150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FHI56_RS06175	COG2384	SAM-dependent methyltransferase
FHI56_RS06190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FHI56_RS06200	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FHI56_RS06210	COG1088	dTDP-glucose 4,6-dehydratase activity
FHI56_RS06225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FHI56_RS06235	COG0647	UMP catabolic process
FHI56_RS06275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FHI56_RS06285	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FHI56_RS06295	COG0107	imidazoleglycerol-phosphate synthase activity
FHI56_RS06335	COG0366	Alpha amylase catalytic
FHI56_RS06335	COG5263	repeat protein
FHI56_RS06340	COG0366	Alpha amylase catalytic
FHI56_RS06340	COG5263	repeat protein
FHI56_RS06345	COG5263	repeat protein
FHI56_RS06345	COG0366	Alpha amylase catalytic
FHI56_RS06350	COG0772	Belongs to the SEDS family
FHI56_RS06355	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FHI56_RS06370	COG0300	oxidoreductase activity
FHI56_RS06385	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
FHI56_RS06385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FHI56_RS06405	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FHI56_RS06430	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
FHI56_RS06435	COG1438	arginine binding
FHI56_RS06440	COG0497	DNA recombination
FHI56_RS06450	COG2755	lipolytic protein G-D-S-L family
FHI56_RS06460	COG0776	regulation of translation
FHI56_RS06470	COG0167	dihydroorotate dehydrogenase activity
FHI56_RS06475	COG0588	phosphoglycerate mutase activity
FHI56_RS06495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FHI56_RS06500	COG0066	3-isopropylmalate dehydratase activity
FHI56_RS06515	COG0469	pyruvate kinase activity
FHI56_RS06545	COG3842	ATPase activity
FHI56_RS06570	COG0716	FMN binding
FHI56_RS06585	COG0038	chloride channel
FHI56_RS06590	COG0335	large ribosomal subunit rRNA binding
FHI56_RS06630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FHI56_RS06635	COG1956	GAF domain-containing protein
FHI56_RS06640	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FHI56_RS06650	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FHI56_RS06650	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FHI56_RS06655	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FHI56_RS06675	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FHI56_RS06685	COG1215	transferase activity, transferring glycosyl groups
FHI56_RS06690	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FHI56_RS06715	COG0765	amino acid transport
FHI56_RS06720	COG0765	amino acid transport
FHI56_RS06725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS06730	COG1126	abc transporter atp-binding protein
FHI56_RS06735	COG0765	amino acid transport
FHI56_RS06740	COG0765	amino acid transport
FHI56_RS06745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS06750	COG1126	abc transporter atp-binding protein
FHI56_RS06755	COG0745	RESPONSE REGULATOR receiver
FHI56_RS06760	COG5002	protein histidine kinase activity
FHI56_RS06765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FHI56_RS06770	COG2832	Protein of unknown function (DUF454)
FHI56_RS06785	COG2348	transferase activity, transferring amino-acyl groups
FHI56_RS06815	COG0778	Nitroreductase
FHI56_RS06825	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FHI56_RS06835	COG2884	Cell division ATP-binding protein ftsE
FHI56_RS06840	COG2177	Part of the ABC transporter FtsEX involved in
FHI56_RS06850	COG1051	belongs to the nudix hydrolase family
FHI56_RS06855	COG0628	permease
FHI56_RS06870	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHI56_RS06900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FHI56_RS06905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FHI56_RS06935	COG1573	uracil-dna glycosylase
FHI56_RS06965	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
FHI56_RS06970	COG3475	LICD family
FHI56_RS06995	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FHI56_RS07010	COG0561	phosphatase activity
FHI56_RS07025	COG0588	phosphoglycerate mutase activity
FHI56_RS07030	COG0628	permease
FHI56_RS07055	COG4667	esterase of the alpha-beta hydrolase superfamily
FHI56_RS07070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FHI56_RS07100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FHI56_RS07105	COG0022	dehydrogenase e1 component
FHI56_RS07105	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHI56_RS07110	COG0508	dehydrogenase complex catalyzes the overall conversion of
FHI56_RS07120	COG0860	N-Acetylmuramoyl-L-alanine amidase
FHI56_RS07130	COG1523	belongs to the glycosyl hydrolase 13 family
FHI56_RS07135	COG2822	iron ion transport
FHI56_RS07140	COG2837	iron assimilation
FHI56_RS07145	COG0672	)-iron permease
FHI56_RS07150	COG0805	protein transport
FHI56_RS07155	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FHI56_RS07170	COG3842	ATPase activity
FHI56_RS07175	COG3833	ABC-type maltose transport systems, permease component
FHI56_RS07180	COG1175	transmembrane transport
FHI56_RS07190	COG1609	Transcriptional regulator
FHI56_RS07195	COG1640	4-alpha-glucanotransferase
FHI56_RS07210	COG0095	Lipoate-protein ligase
FHI56_RS07225	COG0704	Plays a role in the regulation of phosphate uptake
FHI56_RS07240	COG0581	inorganic phosphate transmembrane transporter activity
FHI56_RS07245	COG0573	inorganic phosphate transmembrane transporter activity
FHI56_RS07255	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FHI56_RS07255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHI56_RS07260	COG0483	inositol monophosphate 1-phosphatase activity
FHI56_RS07270	COG1393	Belongs to the ArsC family
FHI56_RS07275	COG0196	riboflavin kinase activity
FHI56_RS07280	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FHI56_RS07315	COG2873	o-acetylhomoserine
FHI56_RS07320	COG0210	DNA helicase
FHI56_RS07325	COG1115	amino acid carrier protein
FHI56_RS07335	COG2207	Transcriptional regulator
FHI56_RS07335	COG1917	Cupin 2, conserved barrel domain protein
FHI56_RS07340	COG0737	Belongs to the 5'-nucleotidase family
FHI56_RS07345	COG0765	amino acid transport
FHI56_RS07350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS07365	COG0284	orotidine-5'-phosphate decarboxylase activity
FHI56_RS07370	COG0167	dihydroorotate dehydrogenase activity
FHI56_RS07400	COG1293	RNA-binding protein homologous to eukaryotic snRNP
FHI56_RS07410	COG0534	Mate efflux family protein
FHI56_RS07415	COG4607	ABC-type enterochelin transport system periplasmic component
FHI56_RS07435	COG0583	DNA-binding transcription factor activity
FHI56_RS07495	COG1063	alcohol dehydrogenase
FHI56_RS07505	COG1230	cation diffusion facilitator family transporter
FHI56_RS07535	COG1122	ATPase activity
FHI56_RS07545	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHI56_RS07565	COG1136	(ABC) transporter
FHI56_RS07565	COG0577	efflux transmembrane transporter activity
FHI56_RS07585	COG1174	glycine betaine transport
FHI56_RS07605	COG1846	Transcriptional regulator
FHI56_RS07625	COG3527	Alpha-acetolactate decarboxylase
FHI56_RS07630	COG0028	Belongs to the TPP enzyme family
FHI56_RS07655	COG0813	purine-nucleoside phosphorylase activity
FHI56_RS07670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FHI56_RS07680	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FHI56_RS07735	COG1131	(ABC) transporter
FHI56_RS07740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FHI56_RS07745	COG0758	DNA mediated transformation
FHI56_RS07760	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FHI56_RS07770	COG1827	regulation of RNA biosynthetic process
FHI56_RS07780	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FHI56_RS07790	COG2188	Transcriptional regulator
FHI56_RS07795	COG0519	Catalyzes the synthesis of GMP from XMP
FHI56_RS07795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FHI56_RS07805	COG1064	alcohol dehydrogenase
FHI56_RS07820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FHI56_RS07825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS07830	COG1126	abc transporter atp-binding protein
FHI56_RS07835	COG0765	amino acid transport
FHI56_RS07840	COG2824	Alkylphosphonate utilization operon protein PhnA
FHI56_RS07845	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHI56_RS07850	COG0583	DNA-binding transcription factor activity
FHI56_RS07855	COG1388	LysM domain
FHI56_RS07855	COG1705	Flagellar rod assembly protein muramidase FlgJ
FHI56_RS07875	COG0803	Belongs to the bacterial solute-binding protein 9 family
FHI56_RS07875	COG3443	Belongs to the bacterial solute-binding protein 9 family
FHI56_RS07925	COG0720	synthase
FHI56_RS07935	COG0251	oxidation-reduction process
FHI56_RS07950	COG0017	Asparaginyl-tRNA synthetase
FHI56_RS07955	COG0436	Aminotransferase
FHI56_RS07965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FHI56_RS07965	COG1199	ATP-dependent helicase activity
FHI56_RS07975	COG1079	Belongs to the binding-protein-dependent transport system permease family
FHI56_RS07980	COG4603	Belongs to the binding-protein-dependent transport system permease family
FHI56_RS07985	COG3845	ABC transporter
FHI56_RS07990	COG1744	ABC transporter substrate-binding protein PnrA-like
FHI56_RS07995	COG0295	cytidine deaminase activity
FHI56_RS08000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FHI56_RS08005	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FHI56_RS08010	COG2813	Specifically methylates the guanine in position
FHI56_RS08025	COG5002	protein histidine kinase activity
FHI56_RS08030	COG0745	RESPONSE REGULATOR receiver
FHI56_RS08045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FHI56_RS08050	COG4684	Psort location CytoplasmicMembrane, score
FHI56_RS08055	COG4684	Psort location CytoplasmicMembrane, score
FHI56_RS08060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FHI56_RS08090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHI56_RS08095	COG3966	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FHI56_RS08105	COG1696	Membrane protein involved in D-alanine export
FHI56_RS08120	COG1132	(ABC) transporter
FHI56_RS08145	COG0009	L-threonylcarbamoyladenylate synthase
FHI56_RS08150	COG2890	protein-(glutamine-N5) methyltransferase activity
FHI56_RS08160	COG1435	thymidine kinase activity
FHI56_RS08165	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FHI56_RS08170	COG0625	glutathione transferase activity
FHI56_RS08175	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FHI56_RS08200	COG0346	lactoylglutathione lyase activity
FHI56_RS08205	COG3764	Sortase (surface protein transpeptidase)
FHI56_RS08225	COG0488	(ABC) transporter
FHI56_RS08250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FHI56_RS08255	COG1328	CTP reductase activity
FHI56_RS08255	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FHI56_RS08295	COG1196	nuclear chromosome segregation
FHI56_RS08310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FHI56_RS08320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHI56_RS08330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FHI56_RS08350	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHI56_RS08370	COG1011	Hydrolase
FHI56_RS08375	COG1760	l-serine dehydratase
FHI56_RS08380	COG1760	l-serine dehydratase
FHI56_RS08385	COG5492	domain, Protein
FHI56_RS08385	COG3583	domain protein
FHI56_RS08385	COG1621	beta-fructofuranosidase activity
FHI56_RS08445	COG2197	response regulator
FHI56_RS08450	COG4585	Histidine kinase
FHI56_RS08460	COG1131	(ABC) transporter
FHI56_RS08485	COG0443	Heat shock 70 kDa protein
FHI56_RS08490	COG0385	Bile acid
FHI56_RS08500	COG0842	Transport permease protein
FHI56_RS08505	COG1131	(ABC) transporter
FHI56_RS08525	COG0577	efflux transmembrane transporter activity
FHI56_RS08530	COG1136	(ABC) transporter
FHI56_RS08540	COG0745	RESPONSE REGULATOR receiver
FHI56_RS08550	COG2233	PERMEase
FHI56_RS08555	COG3842	ATPase activity
FHI56_RS08565	COG0534	Mate efflux family protein
FHI56_RS08575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHI56_RS08575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FHI56_RS08580	COG1114	Component of the transport system for branched-chain amino acids
FHI56_RS08585	COG1482	cell wall glycoprotein biosynthetic process
FHI56_RS08600	COG3237	CsbD-like
FHI56_RS08615	COG0531	amino acid
FHI56_RS08625	COG1126	abc transporter atp-binding protein
FHI56_RS08630	COG0765	amino acid transport
FHI56_RS08635	COG0765	amino acid transport
FHI56_RS08640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS08645	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FHI56_RS08650	COG0386	Belongs to the glutathione peroxidase family
FHI56_RS08675	COG4989	oxidoreductase activity
FHI56_RS08680	COG1668	transmembrane transport
FHI56_RS08685	COG4152	abc transporter atp-binding protein
FHI56_RS08695	COG2826	transposase and inactivated derivatives, IS30 family
FHI56_RS08705	COG1476	TRANSCRIPTIONal
FHI56_RS08720	COG2514	catechol 2,3-dioxygenase activity
FHI56_RS08725	COG1959	2 iron, 2 sulfur cluster binding
FHI56_RS08735	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FHI56_RS08740	COG0778	Nitroreductase
FHI56_RS08750	COG0656	L-ascorbic acid biosynthetic process
FHI56_RS08760	COG3250	beta-galactosidase activity
FHI56_RS08765	COG2190	(PTS) system
FHI56_RS08765	COG2211	Major facilitator Superfamily
FHI56_RS08770	COG2017	converts alpha-aldose to the beta-anomer
FHI56_RS08775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FHI56_RS08790	COG1609	Transcriptional regulator
FHI56_RS08795	COG0366	Alpha amylase catalytic
FHI56_RS08805	COG5002	protein histidine kinase activity
FHI56_RS08810	COG0745	RESPONSE REGULATOR receiver
FHI56_RS08815	COG0577	efflux transmembrane transporter activity
FHI56_RS08820	COG1136	(ABC) transporter
FHI56_RS08870	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FHI56_RS08875	COG1461	Dihydroxyacetone kinase
FHI56_RS08880	COG2376	Dihydroxyacetone kinase
FHI56_RS08905	COG3590	peptidase
FHI56_RS08925	COG0640	Transcriptional regulator
FHI56_RS08935	COG5263	repeat protein
FHI56_RS08935	COG0366	Alpha amylase catalytic
FHI56_RS08945	COG5263	repeat protein
FHI56_RS08945	COG0366	Alpha amylase catalytic
FHI56_RS08950	COG5263	repeat protein
FHI56_RS08950	COG0366	Alpha amylase catalytic
FHI56_RS08965	COG5263	repeat protein
FHI56_RS08965	COG0366	Alpha amylase catalytic
FHI56_RS08965	COG5263	repeat protein
FHI56_RS08965	COG0366	Alpha amylase catalytic
FHI56_RS08970	COG0366	Alpha amylase catalytic
FHI56_RS08970	COG5263	repeat protein
FHI56_RS08970	COG5263	repeat protein
FHI56_RS08970	COG0366	Alpha amylase catalytic
FHI56_RS08985	COG5263	repeat protein
FHI56_RS08985	COG0366	Alpha amylase catalytic
FHI56_RS09025	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FHI56_RS09025	COG0392	lysyltransferase activity
FHI56_RS09030	COG0679	Auxin Efflux Carrier
FHI56_RS09035	COG0281	malic enzyme
FHI56_RS09045	COG0583	DNA-binding transcription factor activity
FHI56_RS09055	COG0477	Major facilitator Superfamily
FHI56_RS09065	COG0110	maltose O-acetyltransferase activity
FHI56_RS09075	COG5263	repeat protein
FHI56_RS09075	COG0366	Alpha amylase catalytic
FHI56_RS09120	COG0653	protein targeting
FHI56_RS09145	COG1442	glycosyl transferase family 8
FHI56_RS09150	COG1442	glycosyl transferase family 8
FHI56_RS09155	COG1216	Glycosyl transferase, family 2
FHI56_RS09155	COG1442	glycosyl transferase family 8
FHI56_RS09160	COG1442	glycosyl transferase family 8
FHI56_RS09165	COG0438	transferase activity, transferring glycosyl groups
FHI56_RS09180	COG1442	glycosyl transferase family 8
FHI56_RS09185	COG1442	glycosyl transferase family 8
FHI56_RS09190	COG1216	Glycosyl transferase, family 2
FHI56_RS09190	COG1442	glycosyl transferase family 8
FHI56_RS09195	COG0110	maltose O-acetyltransferase activity
FHI56_RS09215	COG0419	ATPase involved in DNA repair
FHI56_RS09220	COG0420	3'-5' exonuclease activity
FHI56_RS09230	COG3064	Membrane
FHI56_RS09245	COG0488	(ABC) transporter
FHI56_RS09250	COG1132	(ABC) transporter
FHI56_RS09255	COG1132	(ABC) transporter
FHI56_RS09280	COG0058	SHG alpha-glucan phosphorylase activity
FHI56_RS09285	COG0297	glycogen (starch) synthase activity
FHI56_RS09290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FHI56_RS09295	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FHI56_RS09300	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FHI56_RS09305	COG1523	belongs to the glycosyl hydrolase 13 family
FHI56_RS09340	COG2197	response regulator
FHI56_RS09345	COG4585	Histidine kinase
FHI56_RS09355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FHI56_RS09360	COG0515	serine threonine protein kinase
FHI56_RS09360	COG2815	serine threonine protein kinase
FHI56_RS09370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FHI56_RS09370	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FHI56_RS09380	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FHI56_RS09395	COG0552	protein localization to endoplasmic reticulum
FHI56_RS09400	COG0561	phosphatase activity
FHI56_RS09405	COG0561	phosphatase activity
FHI56_RS09410	COG1725	Transcriptional regulator
FHI56_RS09415	COG1131	(ABC) transporter
FHI56_RS09425	COG4608	Belongs to the ABC transporter superfamily
FHI56_RS09430	COG0444	Belongs to the ABC transporter superfamily
FHI56_RS09435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHI56_RS09440	COG0601	transmembrane transport
FHI56_RS09445	COG4166	transmembrane transport
FHI56_RS09450	COG4166	transmembrane transport
FHI56_RS09455	COG0280	phosphate acetyltransferase
FHI56_RS09460	COG0564	pseudouridine synthase activity
FHI56_RS09470	COG2357	RelA SpoT domain protein
FHI56_RS09500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FHI56_RS09525	COG0463	Glycosyl transferase, family 2
FHI56_RS09550	COG1442	glycosyl transferase family 8
FHI56_RS09550	COG1216	Glycosyl transferase, family 2
FHI56_RS09575	COG1442	glycosyl transferase family 8
FHI56_RS09575	COG1216	Glycosyl transferase, family 2
FHI56_RS09600	COG1091	dTDP-4-dehydrorhamnose reductase activity
FHI56_RS09610	COG0463	Glycosyl transferase, family 2
FHI56_RS09615	COG2151	metal-sulfur cluster biosynthetic enzyme
FHI56_RS09620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FHI56_RS09625	COG0358	DNA primase activity
FHI56_RS09630	COG1970	mechanosensitive ion channel activity
FHI56_RS09635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FHI56_RS09640	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS09645	COG0436	Aminotransferase
FHI56_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS09655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS09680	COG0765	amino acid transport
FHI56_RS09685	COG1126	abc transporter atp-binding protein
FHI56_RS09705	COG1187	pseudouridine synthase activity
FHI56_RS09745	COG0560	Phosphoserine phosphatase
FHI56_RS09755	COG0187	DNA topoisomerase II activity
FHI56_RS09765	COG1346	cytolysis
FHI56_RS09770	COG1380	Effector of murein hydrolase LrgA
FHI56_RS09775	COG0419	ATPase involved in DNA repair
FHI56_RS09795	COG0519	Catalyzes the synthesis of GMP from XMP
FHI56_RS09835	COG0726	polysaccharide deacetylase
FHI56_RS09840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FHI56_RS09845	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FHI56_RS09860	COG0436	Aminotransferase
FHI56_RS09865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FHI56_RS09935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FHI56_RS09940	COG4122	O-methyltransferase activity
FHI56_RS09945	COG2223	nitrite transmembrane transporter activity
FHI56_RS09965	COG1388	LysM domain
FHI56_RS09965	COG3942	CHAP domain
FHI56_RS09980	COG0583	DNA-binding transcription factor activity
FHI56_RS09985	COG0656	L-ascorbic acid biosynthetic process
FHI56_RS09990	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHI56_RS09990	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FHI56_RS10010	COG1702	phosphate starvation-inducible protein PhoH
FHI56_RS10045	COG0745	RESPONSE REGULATOR receiver
FHI56_RS10075	COG0242	peptide deformylase activity
FHI56_RS10085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FHI56_RS10105	COG0488	(ABC) transporter
FHI56_RS10165	COG0301	tRNA thio-modification
FHI56_RS10170	COG1104	cysteine desulfurase activity
FHI56_RS10180	COG0285	dihydrofolate synthase activity
FHI56_RS10185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FHI56_RS10190	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHI56_RS10190	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FHI56_RS10190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHI56_RS10195	COG1105	Belongs to the carbohydrate kinase PfkB family
FHI56_RS10200	COG1349	DNA-binding transcription factor activity
FHI56_RS10225	COG0439	Biotin carboxylase
FHI56_RS10240	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FHI56_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
FHI56_RS10250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FHI56_RS10270	COG1846	Transcriptional regulator
FHI56_RS10275	COG1024	Enoyl-CoA hydratase
FHI56_RS10280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FHI56_RS10285	COG0527	aspartate kinase activity
FHI56_RS10385	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
FHI56_RS10390	COG1739	Uncharacterized protein family UPF0029
FHI56_RS10400	COG0517	IMP dehydrogenase activity
FHI56_RS10430	COG4471	UPF0298 protein
FHI56_RS10465	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FHI56_RS10470	COG0626	cystathionine gamma-synthase activity
FHI56_RS10475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FHI56_RS10480	COG2244	polysaccharide biosynthetic process
FHI56_RS10500	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FHI56_RS10510	COG2740	Nucleic-acid-binding protein implicated in transcription termination
FHI56_RS10515	COG0195	Participates in both transcription termination and antitermination
FHI56_RS10525	COG1316	TRANSCRIPTIONal
FHI56_RS10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FHI56_RS10535	COG0802	atpase or kinase
FHI56_RS10540	COG2252	PERMEase
FHI56_RS10545	COG0561	phosphatase activity
FHI56_RS10550	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FHI56_RS10560	COG3715	PTS system
FHI56_RS10565	COG3716	PTS system mannose fructose sorbose family IID component
FHI56_RS10580	COG3715	PTS system
FHI56_RS10585	COG3716	PTS system mannose fructose sorbose family IID component
FHI56_RS10610	COG1484	DNA-dependent DNA replication
FHI56_RS10625	COG5002	protein histidine kinase activity
FHI56_RS10630	COG0745	RESPONSE REGULATOR receiver
FHI56_RS10645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHI56_RS10660	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FHI56_RS10670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FHI56_RS10680	COG1464	Belongs to the NlpA lipoprotein family
FHI56_RS10685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FHI56_RS10690	COG1122	ATPase activity
FHI56_RS10695	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FHI56_RS10700	COG0310	cobalt ion transport
FHI56_RS10705	COG0829	nickel cation binding
FHI56_RS10715	COG0830	nickel cation binding
FHI56_RS10725	COG0804	urea catabolic process
FHI56_RS10755	COG2274	protein secretion by the type I secretion system
FHI56_RS10765	COG0671	phosphoesterase, PA-phosphatase related
FHI56_RS10770	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FHI56_RS10780	COG0569	domain protein
FHI56_RS10785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FHI56_RS10795	COG1187	pseudouridine synthase activity
FHI56_RS10800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FHI56_RS10805	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FHI56_RS10825	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FHI56_RS10840	COG1309	transcriptional regulator
FHI56_RS10865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FHI56_RS10870	COG1254	Belongs to the acylphosphatase family
FHI56_RS10885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FHI56_RS10905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FHI56_RS10915	COG0116	Belongs to the methyltransferase superfamily
FHI56_RS10940	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHI56_RS10945	COG3579	cysteine-type endopeptidase activity
FHI56_RS10960	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FHI56_RS10965	COG0577	efflux transmembrane transporter activity
FHI56_RS10975	COG0789	Transcriptional regulator
FHI56_RS10985	COG3279	Response regulator of the LytR AlgR family
FHI56_RS11030	COG1349	DNA-binding transcription factor activity
FHI56_RS11035	COG0561	phosphatase activity
FHI56_RS11060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FHI56_RS11065	COG0564	pseudouridine synthase activity
FHI56_RS11095	COG1116	anion transmembrane transporter activity
FHI56_RS11095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FHI56_RS11100	COG4120	Belongs to the binding-protein-dependent transport system permease family
FHI56_RS11115	COG4589	Belongs to the CDS family
FHI56_RS11135	COG1132	(ABC) transporter
FHI56_RS11140	COG1396	sequence-specific DNA binding
FHI56_RS11150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FHI56_RS11170	COG3732	PTS system glucitol sorbitol-specific
FHI56_RS11175	COG3730	PTS system glucitol sorbitol-specific
FHI56_RS11185	COG3711	transcriptional antiterminator
FHI56_RS11185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FHI56_RS11195	COG0166	Belongs to the GPI family
FHI56_RS11205	COG2190	(PTS) system
FHI56_RS11205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FHI56_RS11205	COG1263	PTS System
FHI56_RS11215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FHI56_RS11220	COG1121	(ABC) transporter
FHI56_RS11230	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FHI56_RS11245	COG4608	Belongs to the ABC transporter superfamily
FHI56_RS11250	COG0444	Belongs to the ABC transporter superfamily
FHI56_RS11255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FHI56_RS11260	COG0601	transmembrane transport
FHI56_RS11265	COG4166	transmembrane transport
FHI56_RS11280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FHI56_RS11285	COG0719	Fe-S assembly protein
FHI56_RS11295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FHI56_RS11315	COG0765	amino acid transport
FHI56_RS11320	COG1126	abc transporter atp-binding protein
FHI56_RS11360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FHI56_RS11385	COG0737	Belongs to the 5'-nucleotidase family
FHI56_RS11390	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FHI56_RS11405	COG0494	nUDIX hydrolase
FHI56_RS11415	COG0504	CTP synthase activity
FHI56_RS11430	COG0668	transmembrane transport
FHI56_RS11510	COG0351	phosphomethylpyrimidine kinase