locus-tag	class	description
FDP16_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FDP16_RS00025	ENOG4105C3G	gtp-binding protein
FDP16_RS00030	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FDP16_RS00035	ENOG4108JA2	transcriptioN-repair coupling factor
FDP16_RS00040	ENOG41082I2	s4 domain protein
FDP16_RS00055	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FDP16_RS00060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FDP16_RS00065	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FDP16_RS00085	ENOG4108RS6	transposase
FDP16_RS00210	ENOG41068JE	domain protein
FDP16_RS00220	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FDP16_RS00230	ENOG4105KFN	sortase, SrtB family
FDP16_RS00235	ENOG4105CHM	Aminotransferase
FDP16_RS00240	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
FDP16_RS00245	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FDP16_RS00250	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FDP16_RS00255	ENOG4105C8V	SAICAR synthetase
FDP16_RS00260	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FDP16_RS00265	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FDP16_RS00275	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FDP16_RS00280	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FDP16_RS00295	ENOG41068JE	domain protein
FDP16_RS00300	ENOG4105C12	Phosphoribosylglycinamide synthetase
FDP16_RS00305	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FDP16_RS00310	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FDP16_RS00350	ENOG4105C83	adenylosuccinate lyase
FDP16_RS00355	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
FDP16_RS00365	ENOG4105CMT	Dihydroxyacetone kinase
FDP16_RS00370	ENOG4108UTZ	Dihydroxyacetone kinase
FDP16_RS00375	ENOG4105VDH	Dihydroxyacetone kinase
FDP16_RS00380	ENOG4105FDP	GntR family transcriptional regulator
FDP16_RS00390	ENOG4108IQ3	PTS system
FDP16_RS00395	ENOG4105ETZ	PTS System
FDP16_RS00400	ENOG4105F3R	pts system mannose fructose sorbose family iid
FDP16_RS00410	ENOG4105E70	isomerase
FDP16_RS00415	ENOG4105D2M	Aldolase
FDP16_RS00420	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FDP16_RS00425	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FDP16_RS00435	ENOG4107ZCW	Low molecular weight phosphotyrosine protein phosphatase
FDP16_RS00475	ENOG4105C0A	alcohol dehydrogenase
FDP16_RS00485	ENOG4105I82	acetyl xylan esterase
FDP16_RS00490	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
FDP16_RS00495	ENOG4108IJ9	(ABC) transporter
FDP16_RS00505	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
FDP16_RS00510	ENOG4105DRS	transport system, permease
FDP16_RS00525	ENOG4107SCR	N-acetylneuraminate lyase
FDP16_RS00570	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FDP16_RS00580	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
FDP16_RS00585	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
FDP16_RS00590	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FDP16_RS00600	ENOG4105D98	threonine synthase
FDP16_RS00605	ENOG4108IUM	Glycogen debranching enzyme
FDP16_RS00610	ENOG4105FKQ	transcriptional regulator
FDP16_RS00615	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
FDP16_RS00620	ENOG4108IUN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FDP16_RS00630	ENOG4105MTF	NrdI protein
FDP16_RS00635	ENOG4105C75	arginyL-tRNA synthetase
FDP16_RS00640	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FDP16_RS00645	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FDP16_RS00650	ENOG4108RS6	transposase
FDP16_RS00665	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FDP16_RS00675	ENOG41067QW	Transcriptional regulator
FDP16_RS00680	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FDP16_RS00685	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FDP16_RS00705	ENOG4105C19	ABC transporter
FDP16_RS00720	ENOG4105CEV	competence damage-inducible protein
FDP16_RS00725	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FDP16_RS00730	ENOG410888K	transcriptional regulator, Spx
FDP16_RS00745	ENOG4105VBH	UPF0297 protein
FDP16_RS00750	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FDP16_RS00755	ENOG4105VPH	UPF0473 protein
FDP16_RS00760	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FDP16_RS00770	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FDP16_RS00785	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FDP16_RS00805	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FDP16_RS00815	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
FDP16_RS00820	ENOG4105HTX	biosynthesis protein
FDP16_RS00840	ENOG4105CMR	udp-glucose 4-epimerase
FDP16_RS00845	ENOG4108RYC	glycosyltransferase
FDP16_RS00855	ENOG4105KPE	licD family
FDP16_RS00865	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FDP16_RS00885	ENOG4108YBP	pseudouridine synthase
FDP16_RS00890	ENOG4105BZ4	penicillin-binding protein
FDP16_RS00925	ENOG4105CE9	30S ribosomal protein S2
FDP16_RS00930	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FDP16_RS00940	ENOG4105KEX	transcriptional regulator, ctsr
FDP16_RS00965	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FDP16_RS00985	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FDP16_RS00990	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FDP16_RS00995	ENOG41065RQ	ADP-ribosylation crystallin J1
FDP16_RS01010	ENOG4105D9M	gamma-glutamylcysteine synthetase
FDP16_RS01015	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FDP16_RS01030	ENOG4107QYV	phosphohexose isomerase
FDP16_RS01050	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FDP16_RS01055	ENOG4105CH2	amidohydrolase
FDP16_RS01060	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FDP16_RS01070	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FDP16_RS01075	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FDP16_RS01080	ENOG4105BZ1	(ABC) transporter
FDP16_RS01085	ENOG4105BZ1	(ABC) transporter
FDP16_RS01100	ENOG4107Z0P	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FDP16_RS01140	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FDP16_RS01155	ENOG4107BMA	Transglycosylase associated protein
FDP16_RS01185	ENOG4107UWA	esterase
FDP16_RS01190	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FDP16_RS01200	ENOG4105CDH	Citrulline--aspartate ligase
FDP16_RS01205	ENOG4105CH7	arginosuccinase
FDP16_RS01210	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FDP16_RS01230	ENOG41084B3	50S ribosomal protein l34
FDP16_RS01240	ENOG4105VMP	Transcriptional regulator
FDP16_RS01260	ENOG4105F8V	Hydrolase, tatD family
FDP16_RS01270	ENOG4105CHR	reductase
FDP16_RS01275	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FDP16_RS01295	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FDP16_RS01300	ENOG4105DJV	ribulose-phosphate 3-epimerase
FDP16_RS01305	ENOG4105FJ0	thiamine
FDP16_RS01315	ENOG4105EQI	Metal Dependent Phosphohydrolase
FDP16_RS01320	ENOG4105DFT	pur operon repressor
FDP16_RS01330	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FDP16_RS01335	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FDP16_RS01340	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FDP16_RS01345	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FDP16_RS01350	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FDP16_RS01375	ENOG4105DRP	amino acid AbC transporter
FDP16_RS01385	ENOG4105CDA	abc transporter atp-binding protein
FDP16_RS01500	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
FDP16_RS01510	ENOG4106ETB	IIa component
FDP16_RS01520	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
FDP16_RS01540	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FDP16_RS01550	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FDP16_RS01555	ENOG4105KNE	Phosphatidate cytidylyltransferase
FDP16_RS01560	ENOG4105DZP	Membrane-associated zinc metalloprotease
FDP16_RS01565	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FDP16_RS01570	ENOG4105KWG	Pfam:DUF1696
FDP16_RS01585	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FDP16_RS01595	ENOG4105C88	aminopeptidase
FDP16_RS01605	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FDP16_RS01620	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FDP16_RS01625	ENOG4105E5G	Alpha beta hydrolase fold
FDP16_RS01640	ENOG4105K63	Thioredoxin
FDP16_RS01645	ENOG4105DPN	Oligoendopeptidase f
FDP16_RS01650	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FDP16_RS01655	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FDP16_RS01660	ENOG4105D7W	serine acetyltransferase
FDP16_RS01680	ENOG4105C8N	cysteinyl-tRNA synthetase
FDP16_RS01685	ENOG4105KEB	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FDP16_RS01700	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FDP16_RS01705	ENOG4105M0M	Tetracycline resistance protein
FDP16_RS01710	ENOG4105EPR	degv family
FDP16_RS01715	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FDP16_RS01720	ENOG4108UJD	30S ribosomal protein S9
FDP16_RS01775	ENOG4105D7K	pfkb domain protein
FDP16_RS01780	ENOG4108Z5V	transcriptional regulator, merr family
FDP16_RS01785	ENOG4108KR4	dihydrodipicolinate reductase
FDP16_RS01795	ENOG4105VUC	UPF0237 protein
FDP16_RS01800	ENOG4105CAG	UPF0210 protein
FDP16_RS01810	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FDP16_RS01815	ENOG4108UZE	carboxy-peptidase
FDP16_RS01840	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FDP16_RS01845	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDP16_RS01850	ENOG4105CFG	Acts as a chaperone (By similarity)
FDP16_RS01860	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FDP16_RS01865	ENOG4105EEN	pathogenesis
FDP16_RS01870	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FDP16_RS01875	ENOG4105DWF	phosphomethylpyrimidine kinase
FDP16_RS01880	ENOG4105PUK	Membrane
FDP16_RS01885	ENOG4108UIC	UPF0340 protein
FDP16_RS01890	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FDP16_RS01895	ENOG4108Z1Y	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling (By similarity)
FDP16_RS01905	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FDP16_RS01920	ENOG4105D2N	Aldolase
FDP16_RS01960	ENOG4105VB9	50S ribosomal protein l28
FDP16_RS01980	ENOG4108M15	ABC transporter
FDP16_RS01990	ENOG4105BZU	Histidine kinase
FDP16_RS01995	ENOG4108S01	response regulator
FDP16_RS02005	ENOG4108ZP8	Acetolactate synthase small subunit
FDP16_RS02010	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FDP16_RS02015	ENOG4105C7B	Threonine dehydratase
FDP16_RS02030	ENOG4105CDA	abc transporter atp-binding protein
FDP16_RS02035	ENOG4105E5Q	amino acid AbC transporter
FDP16_RS02045	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FDP16_RS02050	ENOG4108SQ7	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FDP16_RS02055	ENOG4105ESV	Glycosyl transferase, family 4
FDP16_RS02065	ENOG4105JRK	feS assembly protein SufD
FDP16_RS02070	ENOG4105C9B	Cysteine desulfurase
FDP16_RS02075	ENOG4108UNV	SUF system FeS assembly protein, NifU family
FDP16_RS02080	ENOG4105DIW	FeS assembly protein SUFB
FDP16_RS02090	ENOG4105DIB	Oligopeptide-binding protein
FDP16_RS02095	ENOG4105DIB	Oligopeptide-binding protein
FDP16_RS02100	ENOG4105DIB	Oligopeptide-binding protein
FDP16_RS02105	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FDP16_RS02110	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FDP16_RS02115	ENOG4105C3U	ABC transporter
FDP16_RS02120	ENOG4108JQ7	(ABC) transporter
FDP16_RS02155	ENOG4105CGU	Enoyl-CoA hydratase
FDP16_RS02160	ENOG4105NTK	Transcriptional repressor Mpra
FDP16_RS02165	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FDP16_RS02180	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FDP16_RS02185	ENOG4105CHR	reductase
FDP16_RS02200	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FDP16_RS02205	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FDP16_RS02210	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FDP16_RS02215	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FDP16_RS02235	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FDP16_RS02260	ENOG4105F3R	pts system mannose fructose sorbose family iid
FDP16_RS02265	ENOG4105ETZ	PTS System
FDP16_RS02280	ENOG4108KP7	hydrolase
FDP16_RS02290	ENOG4105C7N	Xanthine uracil vitamin C permease
FDP16_RS02295	ENOG4105K8N	protein family UPF0079, ATPase
FDP16_RS02300	ENOG4108MK9	spermidine N(1)-acetyltransferase
FDP16_RS02305	ENOG4108KGH	TRANSCRIPTIONal
FDP16_RS02315	ENOG4105K59	histidine triad (HIT) protein
FDP16_RS02335	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FDP16_RS02340	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FDP16_RS02345	ENOG4105CHV	Transcription elongation factor NusA
FDP16_RS02350	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
FDP16_RS02360	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FDP16_RS02365	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FDP16_RS02370	ENOG4105CE4	GlcNAc 6-P deacetylase
FDP16_RS02400	ENOG4105D5G	Transposase
FDP16_RS02425	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FDP16_RS02430	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FDP16_RS02460	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FDP16_RS02470	ENOG4105CJN	penicillin-binding protein
FDP16_RS02475	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FDP16_RS02480	ENOG4105C1J	atp-dependent rna helicase
FDP16_RS02490	ENOG4105CDA	abc transporter atp-binding protein
FDP16_RS02500	ENOG4105C3M	thioredoxin reductase
FDP16_RS02505	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FDP16_RS02510	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FDP16_RS02515	ENOG4108Z9I	-acetyltransferase
FDP16_RS02535	ENOG4105CTZ	aminopeptidase c
FDP16_RS02540	ENOG4105BZ4	penicillin-binding protein
FDP16_RS02545	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
FDP16_RS02550	ENOG4108UKS	UPF0398 protein
FDP16_RS02555	ENOG4105XWG	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation (By similarity)
FDP16_RS02565	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FDP16_RS02570	ENOG41070VT	
FDP16_RS02575	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FDP16_RS02580	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FDP16_RS02585	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FDP16_RS02590	ENOG4105ZAD	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FDP16_RS02595	ENOG4105C25	Primosomal protein n'
FDP16_RS02600	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FDP16_RS02605	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FDP16_RS02610	ENOG4108ZF3	Phosphatase
FDP16_RS02615	ENOG4105D9P	serine threonine protein kinase
FDP16_RS02625	ENOG4105ENE	Histidine kinase
FDP16_RS02640	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FDP16_RS02650	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FDP16_RS02670	ENOG41081UC	Inherit from COG: Competence protein
FDP16_RS02755	ENOG4105EVI	UPF0374 protein
FDP16_RS02760	ENOG410902V	Modulates RecA activity (By similarity)
FDP16_RS02765	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FDP16_RS02770	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FDP16_RS02775	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FDP16_RS02780	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FDP16_RS02805	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FDP16_RS02835	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FDP16_RS02845	ENOG4105CI1	PTS System
FDP16_RS02855	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FDP16_RS02875	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FDP16_RS02890	ENOG4105DFU	Cell wall formation (By similarity)
FDP16_RS02910	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FDP16_RS02920	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FDP16_RS02925	ENOG4105US7	Histidine kinase
FDP16_RS02940	ENOG4108RWN	rrna methyltransferase
FDP16_RS02965	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FDP16_RS02970	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FDP16_RS02985	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
FDP16_RS02990	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FDP16_RS02995	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FDP16_RS03000	ENOG4105FE9	pseudouridine synthase
FDP16_RS03005	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FDP16_RS03010	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FDP16_RS03015	ENOG4105C1A	potassium transporter peripheral membrane
FDP16_RS03025	ENOG4108SAX	Membrane
FDP16_RS03030	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FDP16_RS03040	ENOG4105N5T	Radical SAM Protein
FDP16_RS03060	ENOG4105DKW	ABC transporter
FDP16_RS03065	ENOG4105C02	permease
FDP16_RS03105	ENOG4107414	GntR family transcriptional regulator
FDP16_RS03110	ENOG4105C5Y	PTS System
FDP16_RS03115	ENOG4105CG3	alpha amylase, catalytic region
FDP16_RS03125	ENOG4105F1A	Pyruvate formate-lyase
FDP16_RS03130	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FDP16_RS03155	ENOG41061M1	UPF0337 protein
FDP16_RS03165	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FDP16_RS03190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FDP16_RS03225	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
FDP16_RS03230	ENOG4105C28	cystathionine
FDP16_RS03235	ENOG4105C87	Aminotransferase class I and II
FDP16_RS03240	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FDP16_RS03245	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FDP16_RS03250	ENOG4105WUC	UPF0298 protein
FDP16_RS03255	ENOG4105CP9	extracellular ligand-binding receptor
FDP16_RS03260	ENOG4105C32	Amino acid ABC transporter (Permease)
FDP16_RS03265	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
FDP16_RS03270	ENOG4105C0Z	ABC transporter
FDP16_RS03275	ENOG4108IV0	ABC, transporter
FDP16_RS03280	ENOG41080XP	Cbs domain
FDP16_RS03285	ENOG4108JYZ	YitT family
FDP16_RS03290	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FDP16_RS03295	ENOG4105FA2	dna polymerase iii
FDP16_RS03300	ENOG41063V3	Involved in initiation control of chromosome replication (By similarity)
FDP16_RS03305	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FDP16_RS03310	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FDP16_RS03320	ENOG41080E8	Transcriptional regulator, Spx MgsR family
FDP16_RS03325	ENOG4105CSM	endonuclease III
FDP16_RS03340	ENOG4105CGK	Exodeoxyribonuclease III
FDP16_RS03355	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FDP16_RS03365	ENOG4105E98	transcriptional regulator DeoR family
FDP16_RS03375	ENOG4108YZG	isomerase
FDP16_RS03380	ENOG4105DE4	1-phosphofructokinase
FDP16_RS03385	ENOG4105D2M	Aldolase
FDP16_RS03390	ENOG4105CID	antiterminator
FDP16_RS03410	ENOG4105VMP	Transcriptional regulator
FDP16_RS03440	ENOG4105CJZ	response regulator
FDP16_RS03445	ENOG4105EWM	Histidine kinase
FDP16_RS03475	ENOG4105C19	ABC transporter
FDP16_RS03485	ENOG4105CJ1	ABC, transporter
FDP16_RS03495	ENOG4105DY9	regulatoR
FDP16_RS03520	ENOG4105R8C	Transcriptional regulator
FDP16_RS03565	ENOG4105C19	ABC transporter
FDP16_RS03575	ENOG4105CUB	amino acid
FDP16_RS03605	ENOG4107R3N	Filamentation induced by cAMP protein fic
FDP16_RS03615	ENOG4105CHR	reductase
FDP16_RS03625	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FDP16_RS03640	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FDP16_RS03650	ENOG4105C5H	ABC transporter
FDP16_RS03665	ENOG4108TIT	dATP pyrophosphohydrolase
FDP16_RS03670	ENOG41067S9	phage shock protein C, PspC
FDP16_RS03680	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FDP16_RS03690	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FDP16_RS03695	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FDP16_RS03700	ENOG4105E5D	amino acid
FDP16_RS03705	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FDP16_RS03710	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FDP16_RS03715	ENOG4105QNR	S1 RNA binding domain protein
FDP16_RS03720	ENOG4106E6V	UPF0346 protein
FDP16_RS03725	ENOG4105C9A	Phoh family
FDP16_RS03735	ENOG4105DCF	alanine dehydrogenase
FDP16_RS03740	ENOG41068WN	
FDP16_RS03750	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FDP16_RS03755	ENOG4107YR5	Diacylglycerol kinase
FDP16_RS03760	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FDP16_RS03775	ENOG4108JW7	Maf-like protein
FDP16_RS03780	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FDP16_RS03785	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FDP16_RS03790	ENOG4105C6X	Major Facilitator
FDP16_RS03795	ENOG410861F	50S ribosomal protein L33
FDP16_RS03805	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FDP16_RS03810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FDP16_RS03825	ENOG41088CC	tellurite resistance protein tehB
FDP16_RS03845	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
FDP16_RS03850	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FDP16_RS03865	ENOG4108Z40	Transcriptional regulator
FDP16_RS03870	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
FDP16_RS03875	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FDP16_RS03890	ENOG4105E0A	ABC, transporter
FDP16_RS03895	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
FDP16_RS03900	ENOG4105DC7	peptidase M24
FDP16_RS03905	ENOG4105ETE	Transcriptional regulator (LacI family
FDP16_RS03910	ENOG4105W2C	Glycosyl transferase
FDP16_RS03915	ENOG4105BZF	Glycosyl transferase (Group 1
FDP16_RS03930	ENOG4105C22	threonyL-tRNA synthetase
FDP16_RS03950	ENOG4105DRP	amino acid AbC transporter
FDP16_RS03955	ENOG4105EAD	ABC transporter
FDP16_RS03960	ENOG4107RP9	extracellular solute-binding protein, family 3
FDP16_RS03965	ENOG4105CDA	abc transporter atp-binding protein
FDP16_RS03970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FDP16_RS03975	ENOG4105BZU	Histidine kinase
FDP16_RS03980	ENOG4105Q2H	domain protein
FDP16_RS03985	ENOG4105WD1	Membrane
FDP16_RS03990	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FDP16_RS03995	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FDP16_RS04000	ENOG4108HCJ	Hydrolase
FDP16_RS04005	ENOG410667J	hydrolase
FDP16_RS04010	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FDP16_RS04015	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FDP16_RS04020	ENOG4108NNR	transporter substrate-binding protein
FDP16_RS04025	ENOG4108PJD	permease
FDP16_RS04040	ENOG410906U	SprT-like
FDP16_RS04050	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FDP16_RS04055	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FDP16_RS04060	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FDP16_RS04085	ENOG4105CFP	Peptidase U32
FDP16_RS04100	ENOG4105VEM	Conserved domain protein
FDP16_RS04105	ENOG4105VKD	bioY protein
FDP16_RS04115	ENOG4105DC8	reductase
FDP16_RS04120	ENOG4107X8C	Efflux transporter RND family MFP subunit
FDP16_RS04125	ENOG4105C19	ABC transporter
FDP16_RS04130	ENOG4107RBB	ABC transporter, permease
FDP16_RS04135	ENOG4105CRK	lysyL-tRNA synthetase
FDP16_RS04145	ENOG4108Z66	YbaK ebsC protein
FDP16_RS04165	ENOG4105CNI	cell division protein FtsW
FDP16_RS04170	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FDP16_RS04175	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FDP16_RS04190	ENOG4105X1N	Glycosyl transferase family 8
FDP16_RS04195	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FDP16_RS04230	ENOG4105K64	Glycosyl transferase, family 2
FDP16_RS04240	ENOG4105EY8	ABC transporter
FDP16_RS04250	ENOG4107T7U	Sulfatase
FDP16_RS04270	ENOG4105CAT	Cytidine monophosphate kinase
FDP16_RS04280	ENOG4105VJV	50s ribosomal protein L35
FDP16_RS04285	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FDP16_RS04295	ENOG4108UK2	deaminase
FDP16_RS04305	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FDP16_RS04310	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FDP16_RS04340	ENOG4108U05	Transcriptional regulator
FDP16_RS04350	ENOG4105WH5	Teichoic acid glycosylation protein
FDP16_RS04355	ENOG410807C	QueT transporter
FDP16_RS04360	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FDP16_RS04365	ENOG4105CBD	Diacylglycerol kinase
FDP16_RS04370	ENOG4108IUM	Glycogen debranching enzyme
FDP16_RS04395	ENOG4105DR4	Methyltransferase
FDP16_RS04400	ENOG4105FF2	Type I DHQase
FDP16_RS04405	ENOG4105E2X	shikimate dehydrogenase
FDP16_RS04410	ENOG4105D49	3-dehydroquinate synthase
FDP16_RS04420	ENOG4105EVN	Prephenate dehydrogenase
FDP16_RS04425	ENOG4105WZB	UPF0342 protein
FDP16_RS04430	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FDP16_RS04440	ENOG4105CQC	Prephenate dehydratase
FDP16_RS04445	ENOG4108RCF	TRANSCRIPTIONal
FDP16_RS04450	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FDP16_RS04455	ENOG4105WT3	Transcriptional regulator
FDP16_RS04460	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FDP16_RS04490	ENOG4105BZ1	(ABC) transporter
FDP16_RS04500	ENOG4108V15	phosphotransferase enzyme family
FDP16_RS04505	ENOG4108IUK	alpha amylase, catalytic
FDP16_RS04530	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
FDP16_RS04535	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FDP16_RS04545	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FDP16_RS04550	ENOG4107Z2D	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
FDP16_RS04555	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FDP16_RS04560	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FDP16_RS04565	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FDP16_RS04570	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FDP16_RS04575	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FDP16_RS04580	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FDP16_RS04585	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FDP16_RS04590	ENOG41083RF	phosphoribosyl-ATP pyrophosphatase
FDP16_RS04630	ENOG4108JJA	ABC, transporter
FDP16_RS04680	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FDP16_RS04685	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FDP16_RS04695	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FDP16_RS04700	ENOG4108IXY	short-chain dehydrogenase reductase
FDP16_RS04710	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FDP16_RS04720	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FDP16_RS04730	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FDP16_RS04735	ENOG4105CVG	Homoserine O-transsuccinylase
FDP16_RS04755	ENOG4105EGD	dinuclear metal center protein, YbgI family
FDP16_RS04760	ENOG4107VFR	oxidoreductase
FDP16_RS04765	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FDP16_RS04775	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FDP16_RS04785	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FDP16_RS04795	ENOG4108Z7F	N-acetyltransferase
FDP16_RS04800	ENOG4106N3A	copper homeostasis protein cutc
FDP16_RS04805	ENOG4105UNS	Pfam:DUF419
FDP16_RS04810	ENOG4105BZ1	(ABC) transporter
FDP16_RS04815	ENOG4105BZ1	(ABC) transporter
FDP16_RS04835	ENOG4108UT2	hemolysin iii
FDP16_RS04850	ENOG4105D1Q	UPF0246 protein
FDP16_RS04900	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FDP16_RS04915	ENOG4105CHM	Aminotransferase
FDP16_RS04945	ENOG4105C5S	asparaginyl-tRNA synthetase
FDP16_RS04960	ENOG4105BZ1	(ABC) transporter
FDP16_RS04965	ENOG4105C5H	ABC transporter
FDP16_RS05000	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FDP16_RS05020	ENOG4108Z4K	mutator MutT protein
FDP16_RS05040	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FDP16_RS05055	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FDP16_RS05065	ENOG4105CXT	aspartate transcarbamylase
FDP16_RS05070	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FDP16_RS05075	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FDP16_RS05080	ENOG4105DSE	periplasmic solute binding protein
FDP16_RS05095	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FDP16_RS05130	ENOG410667J	hydrolase
FDP16_RS05135	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FDP16_RS05160	ENOG41086D8	Transcriptional regulator
FDP16_RS05165	ENOG41079CX	
FDP16_RS05175	ENOG4108W2W	
FDP16_RS05185	ENOG4105K5M	30s ribosomal protein S16
FDP16_RS05190	ENOG4105VB6	UPF0109 protein
FDP16_RS05200	ENOG4105CZN	Potassium uptake protein
FDP16_RS05205	ENOG4107ZYR	domain protein
FDP16_RS05230	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FDP16_RS05235	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FDP16_RS05245	ENOG4105EG2	ABC transporter, permease
FDP16_RS05260	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FDP16_RS05290	ENOG4108RG0	uracil-dna glycosylase
FDP16_RS05300	ENOG4105CPQ	Dehydrogenase
FDP16_RS05310	ENOG4108VXD	carboxy-peptidase
FDP16_RS05440	ENOG41082DI	50s ribosomal protein l31
FDP16_RS05445	ENOG4105SFS	phosphoesterase RecJ domain protein
FDP16_RS05470	ENOG4106A8V	Protein CrcB homolog
FDP16_RS05475	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FDP16_RS05500	ENOG4108V16	CRISPR-associated protein
FDP16_RS05505	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FDP16_RS05510	ENOG4105E66	phosphoriboisomerase A
FDP16_RS05515	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
FDP16_RS05520	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
FDP16_RS05525	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FDP16_RS05550	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FDP16_RS05555	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FDP16_RS05560	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FDP16_RS05565	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FDP16_RS05580	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FDP16_RS05585	ENOG4108Z4K	mutator MutT protein
FDP16_RS05595	ENOG4105CGH	5'-nucleotidase
FDP16_RS05600	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FDP16_RS05605	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FDP16_RS05630	ENOG41075D4	Aminoglycoside 6-adenylyltransferase
FDP16_RS05635	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FDP16_RS05640	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FDP16_RS05660	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FDP16_RS05675	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FDP16_RS05680	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FDP16_RS05685	ENOG4108Z6X	(sortase) family
FDP16_RS05700	ENOG4105W5Q	DNA repair protein (RadC
FDP16_RS05725	ENOG4105C3J	Cysteine desulfurase
FDP16_RS05730	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FDP16_RS05750	ENOG4105EMS	pseudouridine synthase
FDP16_RS05755	ENOG4108IJ2	phosphate acetyltransferase
FDP16_RS05760	ENOG4105CEN	a g-specific adenine glycosylase
FDP16_RS05780	ENOG4105FH5	Membrane
FDP16_RS05785	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FDP16_RS05795	ENOG4105CKU	formyltetrahydrofolate synthetase
FDP16_RS05800	ENOG4107Y3V	-acetyltransferase
FDP16_RS05820	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FDP16_RS05825	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FDP16_RS05840	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FDP16_RS05850	ENOG4105DFK	Polyphosphate glucokinase
FDP16_RS05860	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FDP16_RS05865	ENOG4105CID	antiterminator
FDP16_RS05870	ENOG4108UW5	maltose o-acetyltransferase
FDP16_RS05875	ENOG4105C79	DNA protecting protein DprA
FDP16_RS05880	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FDP16_RS05910	ENOG4107RUY	(E1 component), alpha subunit
FDP16_RS05915	ENOG4105CPP	Dehydrogenase, E1 component
FDP16_RS05920	ENOG4107QKR	Dehydrogenase
FDP16_RS05930	ENOG4105DF9	Lipoate-protein, ligase
FDP16_RS05940	ENOG4108XZ3	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division (By similarity)
FDP16_RS05955	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDP16_RS05990	ENOG41065S2	pneumococcal vaccine antigen
FDP16_RS06000	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FDP16_RS06005	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FDP16_RS06010	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FDP16_RS06015	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FDP16_RS06020	ENOG4107104	thymidine kinase
FDP16_RS06025	ENOG41069HH	4-oxalocrotonate tautomerase
FDP16_RS06030	ENOG4107QKR	Dehydrogenase
FDP16_RS06040	ENOG4107RUY	(E1 component), alpha subunit
FDP16_RS06055	ENOG4107QMU	Mate efflux family protein
FDP16_RS06060	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
FDP16_RS06065	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FDP16_RS06070	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FDP16_RS06075	ENOG4107SJW	iron permease, FTR1
FDP16_RS06080	ENOG4105DBE	peroxidase
FDP16_RS06085	ENOG410650H	(LipO)protein
FDP16_RS06090	ENOG4105CMQ	Chloride channel
FDP16_RS06110	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FDP16_RS06120	ENOG4107QIV	Cytochrome c biogenesis protein
FDP16_RS06125	ENOG4105C2F	Histidine kinase
FDP16_RS06130	ENOG4105EQD	regulatoR
FDP16_RS06135	ENOG4105E0X	reductase
FDP16_RS06140	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDP16_RS06150	ENOG4107QIV	Cytochrome c biogenesis protein
FDP16_RS06155	ENOG4108YBA	Histidine kinase
FDP16_RS06160	ENOG4108WZ2	response regulator
FDP16_RS06170	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FDP16_RS06205	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FDP16_RS06210	ENOG4108VZM	50s ribosomal protein L10
FDP16_RS06215	ENOG4105TMB	Formate nitrite transporter
FDP16_RS06220	ENOG4108J5H	Homocysteine s-methyltransferase
FDP16_RS06225	ENOG4108IQI	permease
FDP16_RS06230	ENOG4107X35	defense response to bacterium
FDP16_RS06235	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FDP16_RS06240	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FDP16_RS06245	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FDP16_RS06250	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FDP16_RS06255	ENOG4105DKQ	ROK family
FDP16_RS06265	ENOG4105C5H	ABC transporter
FDP16_RS06270	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FDP16_RS06275	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FDP16_RS06280	ENOG4105EPR	degv family
FDP16_RS06290	ENOG4105DM4	PTS System
FDP16_RS06295	ENOG4105DE4	1-phosphofructokinase
FDP16_RS06300	ENOG4105E98	transcriptional regulator DeoR family
FDP16_RS06305	ENOG4108TYN	CAAX amino terminal protease family protein
FDP16_RS06315	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
FDP16_RS06325	ENOG4105CSA	Coproporphyrinogen iii oxidase
FDP16_RS06340	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FDP16_RS06345	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FDP16_RS06350	ENOG4105CHR	reductase
FDP16_RS06355	ENOG4106611	bacteriocin immunity
FDP16_RS06360	ENOG4105C34	Pseudouridine synthase
FDP16_RS06370	ENOG4105DUM	transcriptional regulator, lysR family
FDP16_RS06375	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FDP16_RS06380	ENOG4105DIB	Oligopeptide-binding protein
FDP16_RS06385	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FDP16_RS06395	ENOG4105K46	50S ribosomal protein l27
FDP16_RS06405	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FDP16_RS06415	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FDP16_RS06420	ENOG4105C3J	Cysteine desulfurase
FDP16_RS06450	ENOG4108HM4	ABC transporter
FDP16_RS06455	ENOG4105D38	putrescine abc transporter
FDP16_RS06460	ENOG4105D56	permease protein
FDP16_RS06465	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FDP16_RS06470	ENOG4105D4A	Cell wall formation (By similarity)
FDP16_RS06475	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FDP16_RS06480	ENOG4105D6E	homoserine dehydrogenase
FDP16_RS06495	ENOG4105UIB	(ABC) transporter
FDP16_RS06500	ENOG4108JQ9	ABC transporter
FDP16_RS06505	ENOG4105DIH	basic membrane
FDP16_RS06510	ENOG4105KG3	cytidine deaminase
FDP16_RS06515	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FDP16_RS06520	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
FDP16_RS06525	ENOG4107Y49	methyltransferase
FDP16_RS06530	ENOG4105CS9	pantothenic acid kinase
FDP16_RS06535	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FDP16_RS06600	ENOG4108IBT	Inherit from COG: transposase
FDP16_RS06640	ENOG4105DER	m42 family
FDP16_RS06665	ENOG4105CMR	udp-glucose 4-epimerase
FDP16_RS06675	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FDP16_RS06680	ENOG4108IJ9	(ABC) transporter
FDP16_RS06685	ENOG4107RK0	Sucrose phosphorylase
FDP16_RS06700	ENOG4107YY3	extracellular solute-binding protein family 1
FDP16_RS06705	ENOG4105DME	alpha-galactosidase
FDP16_RS06710	ENOG4108R6W	Transcriptional regulator, ARAC family
FDP16_RS06715	ENOG4105CQ4	Transcriptional regulator
FDP16_RS06730	ENOG4105C6E	dna polymerase iii
FDP16_RS06745	ENOG4107XNU	peptidase
FDP16_RS06785	ENOG4105E90	ABC transporter
FDP16_RS06810	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FDP16_RS06815	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FDP16_RS06865	ENOG4105DBI	uridine monophosphokinase
FDP16_RS06880	ENOG4108ZJ4	polysaccharide deacetylase
FDP16_RS06895	ENOG4105US7	Histidine kinase
FDP16_RS06900	ENOG4108STX	response regulator
FDP16_RS06940	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FDP16_RS06945	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FDP16_RS06950	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FDP16_RS06955	ENOG4105E2Z	phosphate ABC transporter (Permease
FDP16_RS06960	ENOG4105C8U	phosphate abc transporter
FDP16_RS06970	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FDP16_RS06975	ENOG4105ECY	inositol monophosphatase
FDP16_RS06985	ENOG41090SU	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress (By similarity)
FDP16_RS06990	ENOG4105DTN	riboflavin biosynthesis protein ribF
FDP16_RS06995	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FDP16_RS07030	ENOG4105BZ1	(ABC) transporter
FDP16_RS07050	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FDP16_RS07055	ENOG4105I2S	Part of the ABC transporter complex hrt involved in hemin import. Responsible for the translocation of the substrate across the membrane (By similarity)
FDP16_RS07095	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FDP16_RS07115	ENOG4105CJ1	ABC, transporter
FDP16_RS07145	ENOG4107FQX	Alpha-acetolactate decarboxylase
FDP16_RS07160	ENOG4105BZU	Histidine kinase
FDP16_RS07170	ENOG4107RBB	ABC transporter, permease
FDP16_RS07175	ENOG4105C19	ABC transporter
FDP16_RS07190	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FDP16_RS07200	ENOG4105CJW	magnesium transporter
FDP16_RS07210	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FDP16_RS07225	ENOG4105BZW	Glycerate kinase
FDP16_RS07230	ENOG4105EAC	phosphoserine phosphatase
FDP16_RS07235	ENOG4105DGY	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization (By similarity)
FDP16_RS07250	ENOG4107S0N	DJ-1 family
FDP16_RS07260	ENOG4105HMI	Membrane
FDP16_RS07265	ENOG4105DVT	helicase
FDP16_RS07290	ENOG4105CAK	Cell division ATP-binding protein ftsE
FDP16_RS07320	ENOG4105DCI	Phosphohydrolase
FDP16_RS07330	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
FDP16_RS07355	ENOG4105CP7	Triose-phosphate isomerase
FDP16_RS07360	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FDP16_RS07370	ENOG4105CKK	Glycosyl transferase, family 2
FDP16_RS07385	ENOG4105C4R	Atp-dependent dna helicase
FDP16_RS07425	ENOG4105CA9	Pyruvate kinase
FDP16_RS07430	ENOG4105CTQ	phosphohexokinase
FDP16_RS07435	ENOG4105C0B	DNA polymerase III (alpha subunit)
FDP16_RS07440	ENOG4105CZV	ABC transporter
FDP16_RS07450	ENOG41067MG	lrgb family
FDP16_RS07470	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
FDP16_RS07475	ENOG4108NMT	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon (By similarity)
FDP16_RS07500	ENOG4106YAG	Part of the accessory SecA2 SecY2 system specifically required for export of
FDP16_RS07535	ENOG4105VG1	fes assembly suf system protein
FDP16_RS07540	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FDP16_RS07545	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FDP16_RS07550	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FDP16_RS07555	ENOG4105VCC	30S ribosomal protein S21
FDP16_RS07580	ENOG4105KA3	membrAne
FDP16_RS07585	ENOG4107QN2	dihydrolipoyl dehydrogenase
FDP16_RS07590	ENOG4105CAY	ferredoxin--nadp reductase
FDP16_RS07595	ENOG4105CIE	May be required for sporulation (By similarity)
FDP16_RS07600	ENOG4105CHW	UPF0052 protein
FDP16_RS07605	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FDP16_RS07610	ENOG4105KME	endoribonuclease L-psp
FDP16_RS07620	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDP16_RS07635	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FDP16_RS07645	ENOG4105C8B	TIGR00159 family
FDP16_RS07650	ENOG4105DMS	mur ligase
FDP16_RS07655	ENOG4105F1K	Glutamine amidotransferase
FDP16_RS07710	ENOG4105C5H	ABC transporter
FDP16_RS07725	ENOG4105ZT7	DNA-entry nuclease
FDP16_RS07735	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FDP16_RS07745	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FDP16_RS07750	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FDP16_RS07755	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FDP16_RS07760	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FDP16_RS07765	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FDP16_RS07770	ENOG4107ZFM	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FDP16_RS07775	ENOG4107RFS	it plays a direct role in the translocation of protons across the membrane (By similarity)
FDP16_RS07780	ENOG4105ZA1	atp synthase
FDP16_RS07785	ENOG4105DG6	mannose-6-phosphate isomerase
FDP16_RS07790	ENOG4108TZY	GntR Family Transcriptional Regulator
FDP16_RS07795	ENOG4105CK1	PTS System
FDP16_RS07810	ENOG4105CS2	ec 3.2.1.21
FDP16_RS07815	ENOG41066F8	ROK family
FDP16_RS07830	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FDP16_RS07840	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FDP16_RS07845	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FDP16_RS07850	ENOG4105C26	Dehydrogenase
FDP16_RS07855	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FDP16_RS07860	ENOG4105KRI	phosphocarrier protein (HPr
FDP16_RS07865	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
FDP16_RS07880	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FDP16_RS07905	ENOG4106ZEE	Diacylglycerol kinase
FDP16_RS07930	ENOG4105VZ8	Transcriptional regulator
FDP16_RS07940	ENOG4105C8Y	Acetylornithine aminotransferase
FDP16_RS07945	ENOG4105CAS	nag kinase
FDP16_RS07950	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FDP16_RS07955	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FDP16_RS07960	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FDP16_RS07970	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FDP16_RS07990	ENOG4105CK1	PTS System
FDP16_RS08000	ENOG4105VCP	PTS System
FDP16_RS08005	ENOG4105EMD	TRANSCRIPTIONal
FDP16_RS08015	ENOG4105W3H	MtN3 and saliva related transmembrane protein
FDP16_RS08020	ENOG4105CS2	ec 3.2.1.21
FDP16_RS08040	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FDP16_RS08050	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FDP16_RS08055	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
FDP16_RS08060	ENOG4107QSE	Dipeptidase
FDP16_RS08065	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
FDP16_RS08070	ENOG4105C5B	carbamate kinase
FDP16_RS08075	ENOG4105DBV	ornithine carbamoyltransferase
FDP16_RS08080	ENOG4105CEU	Arginine dihydrolase
FDP16_RS08100	ENOG41090T1	Membrane
FDP16_RS08115	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FDP16_RS08120	ENOG4105TQK	DNA polymerase iii, delta' subunit
FDP16_RS08130	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FDP16_RS08135	ENOG4105KQC	Competence protein
FDP16_RS08145	ENOG4105F6E	Acyl-transferase
FDP16_RS08150	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
FDP16_RS08155	ENOG41060K3	Methyltransferase
FDP16_RS08160	ENOG4105VC4	domain protein
FDP16_RS08165	ENOG4105EDE	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1 (By similarity)
FDP16_RS08170	ENOG4108WWS	isoprenylcysteine carboxyl methyltransferase
FDP16_RS08175	ENOG4105E98	transcriptional regulator DeoR family
FDP16_RS08180	ENOG4105DT3	PTS system, galactitol-specific IIc component
FDP16_RS08200	ENOG4105C1J	atp-dependent rna helicase
FDP16_RS08210	ENOG4108HMX	isocitrate dehydrogenase (NADP)
FDP16_RS08215	ENOG4105BZN	citrate synthase
FDP16_RS08220	ENOG4108I0Z	Aconitate hydratase
FDP16_RS08230	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FDP16_RS08245	ENOG4108U3J	
FDP16_RS08255	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FDP16_RS08260	ENOG4105CPF	Cell wall formation (By similarity)
FDP16_RS08265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FDP16_RS08270	ENOG4107RF6	penicillin-binding protein
FDP16_RS08275	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FDP16_RS08295	ENOG4105G5W	regulator Fur family
FDP16_RS08300	ENOG4105K70	DNA-binding protein
FDP16_RS08305	ENOG4108RCR	degv family
FDP16_RS08315	ENOG4105DQ6	Transposase
FDP16_RS08330	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FDP16_RS08335	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FDP16_RS08345	ENOG4105DX0	Hemolysin A
FDP16_RS08355	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FDP16_RS08365	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FDP16_RS08375	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FDP16_RS08380	ENOG4107IN1	Protein of unknown function (DUF1797)
FDP16_RS08385	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FDP16_RS08395	ENOG4105D29	Helix-turn-helix type 11 domain protein
FDP16_RS08425	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FDP16_RS08430	ENOG4105MMF	Cell division protein DIVIVA
FDP16_RS08445	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
FDP16_RS08450	ENOG4105DFA	alanine racemase domain protein
FDP16_RS08455	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FDP16_RS08465	ENOG4105U2C	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex (By similarity)
FDP16_RS08470	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FDP16_RS08475	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FDP16_RS08485	ENOG4105CI3	gtp-binding protein typa
FDP16_RS08530	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FDP16_RS08540	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FDP16_RS08545	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FDP16_RS08550	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FDP16_RS08555	ENOG4105DDQ	anthranilate synthase
FDP16_RS08560	ENOG4105CRQ	synthase (Component I)
FDP16_RS08565	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FDP16_RS08575	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FDP16_RS08580	ENOG4105MMD	transcriptional regulator
FDP16_RS08585	ENOG41063PX	domain protein
FDP16_RS08590	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FDP16_RS08595	ENOG4106H78	methyltransferase
FDP16_RS08610	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FDP16_RS08630	ENOG4105WT3	Transcriptional regulator
FDP16_RS08645	ENOG4105WT3	Transcriptional regulator
FDP16_RS08650	ENOG4105D0M	Protease HtpX homolog
FDP16_RS08655	ENOG4108V0P	LemA family
FDP16_RS08660	ENOG4105KBX	Transcriptional regulator, TetR family
FDP16_RS08665	ENOG4107Y80	Major Facilitator superfamily
FDP16_RS08675	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FDP16_RS08680	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FDP16_RS08695	ENOG4108JJB	ABC transporter
FDP16_RS08730	ENOG4105C72	UPF0176 protein
FDP16_RS08765	ENOG4108V7D	UPF0397 protein
FDP16_RS08770	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
FDP16_RS08785	ENOG4105EAB	amino acid AbC transporter
FDP16_RS08790	ENOG4105CH2	amidohydrolase
FDP16_RS08800	ENOG4105CDY	transcriptional regulatory protein
FDP16_RS08815	ENOG4105CDE	UPF0348 protein
FDP16_RS08820	ENOG4105DXX	methyltransferase
FDP16_RS08825	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FDP16_RS08830	ENOG4108W2Y	isochorismatase
FDP16_RS08835	ENOG4108WF2	Metal Dependent Phosphohydrolase
FDP16_RS08840	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FDP16_RS08845	ENOG410812S	Rna-binding protein
FDP16_RS08850	ENOG4105CQW	ribosome biogenesis GTPase YqeH
FDP16_RS08855	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
FDP16_RS08900	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FDP16_RS08905	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FDP16_RS08910	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FDP16_RS08925	ENOG4105EUM	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor (By similarity)
FDP16_RS08935	ENOG4105CHM	Aminotransferase
FDP16_RS08945	ENOG4108KP7	hydrolase
FDP16_RS08950	ENOG4107RB3	L-asparaginase
FDP16_RS08960	ENOG4105CB5	ATP-dependent DNA helicase recG
FDP16_RS08965	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FDP16_RS08970	ENOG41082V8	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FDP16_RS08975	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FDP16_RS08980	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FDP16_RS08985	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FDP16_RS08995	ENOG4108RS6	transposase
FDP16_RS09020	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FDP16_RS09025	ENOG4108RS6	transposase
FDP16_RS09040	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
FDP16_RS09045	ENOG4107YDN	peptide deformylase
FDP16_RS09050	ENOG4105EVU	fructokinase
FDP16_RS09055	ENOG4105C5Y	PTS System
FDP16_RS09065	ENOG4105ETE	Transcriptional regulator (LacI family
FDP16_RS09070	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
FDP16_RS09075	ENOG4108IUM	Glycogen debranching enzyme
FDP16_RS09090	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FDP16_RS09095	ENOG4105DC7	peptidase M24
FDP16_RS09100	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FDP16_RS09115	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FDP16_RS09120	ENOG4108UUM	single-stranded DNA-binding protein
FDP16_RS09125	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FDP16_RS09130	ENOG4105CI2	imidazolone-5-propionate hydrolase
FDP16_RS09135	ENOG4105CGP	Urocanate hydratase
FDP16_RS09140	ENOG4105CCS	Glutamate formiminotransferase
FDP16_RS09145	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
FDP16_RS09150	ENOG4105CKU	formyltetrahydrofolate synthetase
FDP16_RS09160	ENOG4105CUB	amino acid
FDP16_RS09165	ENOG4105C84	Histidine ammonia-lyase
FDP16_RS09170	ENOG4105CYW	agmatinase
FDP16_RS09200	ENOG4105CVJ	phosphoglycerate mutase
FDP16_RS09205	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FDP16_RS09220	ENOG4108R6W	Transcriptional regulator, ARAC family
FDP16_RS09225	ENOG4105SYT	Methylenetetrahydrofolate reductase
FDP16_RS09230	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FDP16_RS09255	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FDP16_RS09280	ENOG4105CS2	ec 3.2.1.21
FDP16_RS09290	ENOG4108IJ6	ABC transporter
FDP16_RS09300	ENOG4105C7K	acetolactate synthase
FDP16_RS09305	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FDP16_RS09310	ENOG4108HCJ	Hydrolase
FDP16_RS09315	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FDP16_RS09325	ENOG4108IJ7	Glycine betaine
FDP16_RS09340	ENOG4108W3Q	Transcriptional regulator
FDP16_RS09360	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FDP16_RS09365	ENOG4108UMI	ABC transporter, permease
FDP16_RS09375	ENOG4105D01	(LipO)protein
FDP16_RS09380	ENOG4105E0X	reductase
FDP16_RS09385	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FDP16_RS09390	ENOG4107R37	Glutamate dehydrogenase
FDP16_RS09395	ENOG4108MJ3	acetyltransferase
FDP16_RS09420	ENOG4105D8X	mechanosensitive ion channel
FDP16_RS09430	ENOG4105BZG	amino acid carrier protein
FDP16_RS09435	ENOG4105K63	Thioredoxin
FDP16_RS09450	ENOG4105C98	muts2 protein
FDP16_RS09470	ENOG4105C3F	Signal peptidase i
FDP16_RS09475	ENOG4105C7H	Helicase, RecD TraA family
FDP16_RS09480	ENOG4108RZE	Tetr family transcriptional regulator
FDP16_RS09500	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FDP16_RS09505	ENOG4105C6N	Formate acetyltransferase
FDP16_RS09520	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
FDP16_RS09530	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FDP16_RS09565	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FDP16_RS09570	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
FDP16_RS09575	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FDP16_RS09580	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
FDP16_RS09590	ENOG4105CBX	hi0933 family
FDP16_RS09605	ENOG4107TXC	Transcriptional regulator
FDP16_RS09610	ENOG4105DVA	methyltransferase
FDP16_RS09625	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FDP16_RS09635	ENOG41072GX	Peptidase M22 Glycoprotease
FDP16_RS09640	ENOG4106EHS	UPF0356 protein
FDP16_RS09680	ENOG4105C5F	glutamine synthetase
FDP16_RS09685	ENOG4105KV4	Transcriptional regulator
FDP16_RS09695	ENOG41068JE	domain protein
FDP16_RS09705	ENOG4105BZA	Phosphoglycerate kinase
FDP16_RS09715	ENOG4105C8T	Leucyl-tRNA synthetase
FDP16_RS09750	ENOG4105CXK	mandelate racemase muconate lactonizing
FDP16_RS09755	ENOG4105C5Y	PTS System
FDP16_RS09810	ENOG4107RGM	aldo keto reductase
FDP16_RS09820	ENOG4105CK1	PTS System
FDP16_RS09825	ENOG4105VCP	PTS System
FDP16_RS09830	ENOG4105VZJ	PTS System
FDP16_RS09835	ENOG4108NZE	NAGC-like transcriptional regulator
FDP16_RS09850	ENOG4105C9K	Endothelin-converting enzyme 1
FDP16_RS09855	ENOG4105DIK	(ABC) transporter
FDP16_RS09860	ENOG4105CC5	ABC transporter
FDP16_RS09865	ENOG4105DSE	periplasmic solute binding protein
FDP16_RS09870	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FDP16_RS09895	ENOG4105RV9	Transcriptional regulator
FDP16_RS09900	ENOG4105M5P	UPF0310 protein
FDP16_RS09915	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FDP16_RS09935	ENOG4108MGT	Required for secretion of EsxA and EsxB
FDP16_RS10060	ENOG410646G	Proteins of 100 residues with WXG
FDP16_RS10065	ENOG4105CGH	5'-nucleotidase
FDP16_RS10070	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FDP16_RS10085	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
FDP16_RS10095	ENOG4105D1H	recombination factor protein RarA
FDP16_RS10120	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FDP16_RS10125	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FDP16_RS10135	ENOG4105F3R	pts system mannose fructose sorbose family iid
FDP16_RS10140	ENOG4105ETZ	PTS System
FDP16_RS10160	ENOG4105WH1	Two component transcriptional regulator luxr family
FDP16_RS10165	ENOG4105BZU	Histidine kinase
FDP16_RS10190	ENOG4105RV9	Transcriptional regulator
FDP16_RS10210	ENOG4105CN9	Peptidase m42 family protein
FDP16_RS10265	ENOG4105DA5	(ABC) transporter
FDP16_RS10270	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDP16_RS10275	ENOG4105EUJ	GTP cyclohydrolase i
FDP16_RS10280	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FDP16_RS10285	ENOG4105EEI	dihydropteroate synthase
FDP16_RS10300	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FDP16_RS10350	ENOG4105E2A	Dehydrogenase
FDP16_RS10355	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
FDP16_RS10360	ENOG4107R8N	Glycosyl transferase, family 2
FDP16_RS10370	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FDP16_RS10380	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FDP16_RS10385	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FDP16_RS10405	ENOG4105DHI	Methyltransferase
FDP16_RS10410	ENOG4108IJ9	(ABC) transporter
FDP16_RS10440	ENOG4105C59	p-type ATPase
FDP16_RS10445	ENOG4105NA0	Transcriptional regulator
FDP16_RS10450	ENOG4105DSE	periplasmic solute binding protein
FDP16_RS10460	ENOG4105FDK	ABC transporter
FDP16_RS10465	ENOG41067TZ	transcriptional regulator, MarR family
FDP16_RS10545	ENOG4106BHR	ftsk SpoIIIE family protein
FDP16_RS10610	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
FDP16_RS10635	ENOG4105VTR	Integrase
FDP16_RS10725	ENOG4108ZT0	50S ribosomal protein l17
FDP16_RS10730	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FDP16_RS10735	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FDP16_RS10740	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FDP16_RS10750	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FDP16_RS10760	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FDP16_RS10765	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FDP16_RS10770	ENOG4105VPB	50S ribosomal protein L30
FDP16_RS10775	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FDP16_RS10780	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FDP16_RS10785	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FDP16_RS10790	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FDP16_RS10795	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FDP16_RS10800	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDP16_RS10805	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FDP16_RS10810	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FDP16_RS10815	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FDP16_RS10820	ENOG41082SA	50s ribosomal protein l29
FDP16_RS10825	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FDP16_RS10830	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FDP16_RS10835	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FDP16_RS10840	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FDP16_RS10845	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FDP16_RS10850	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FDP16_RS10855	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FDP16_RS10860	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FDP16_RS10865	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FDP16_RS10875	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FDP16_RS10890	ENOG4105K4P	CoA-binding domain protein
FDP16_RS10895	ENOG4105C2M	dna polymerase I
FDP16_RS10910	ENOG4107XGZ	Hydrolase
FDP16_RS10920	ENOG4107AYK	membrAne
FDP16_RS10940	ENOG4105CUT	histidyl-tRNA synthetase
FDP16_RS10945	ENOG4105VG1	fes assembly suf system protein
FDP16_RS10950	ENOG4105C01	Dihydroxy-acid dehydratase
FDP16_RS10955	ENOG41086FC	50S ribosomal protein l32
FDP16_RS11070	ENOG4105E98	transcriptional regulator DeoR family
FDP16_RS11105	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
FDP16_RS11125	ENOG41063PX	domain protein
FDP16_RS11145	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
FDP16_RS11215	ENOG4105CZX	twitching motility protein
FDP16_RS11220	ENOG4107QHF	type ii secretion system protein e
FDP16_RS11225	ENOG4105PGM	cation diffusion facilitator family transporter
FDP16_RS11235	ENOG4105DJ2	Major Facilitator Superfamily
FDP16_RS11250	ENOG4108M4D	D-alanyl-lipoteichoic acid biosynthesis protein DltD
FDP16_RS11255	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
FDP16_RS11260	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FDP16_RS11305	ENOG4105ECB	domain protein
FDP16_RS11320	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FDP16_RS11335	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
FDP16_RS11340	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FDP16_RS11355	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
FDP16_RS11410	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FDP16_RS11455	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FDP16_RS11460	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FDP16_RS11555	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
FDP16_RS11565	ENOG4105CDU	Replicative dna helicase
FDP16_RS11570	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FDP16_RS11580	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FDP16_RS11585	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FDP16_RS11595	ENOG4105EJQ	L-serine dehydratase
FDP16_RS11610	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
FDP16_RS11615	ENOG4108JJB	ABC transporter
FDP16_RS11620	ENOG4108JJB	ABC transporter
FDP16_RS11625	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FDP16_RS11650	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FDP16_RS11655	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FDP16_RS11660	ENOG4105C31	Tryptophanyl-tRNA synthetase
FDP16_RS11665	ENOG4105C5H	ABC transporter
FDP16_RS11705	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FDP16_RS11710	ENOG4105C0H	protease
FDP16_RS11715	ENOG4105FA0	parb-like partition protein
